| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 1.688e-47 | -107.70 | intracellular part | cellular component | GO:0044424 | 13357 | 1954 | 17570 | 2233 |
PTP4A1,ARHGAP26,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,HMOX2,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,UPP1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,MCM2,ZNF197,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,RUNX1,TPM1,VASH2,SLC25A26,ZNF532,BANP,EPM2AIP1,TRIO,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,CHN1,RBM20,CNST,UBE3A,DHX37,APLF,MED24,TNPO3,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,ANGPT2,MYB,NOM1,RABEPK,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,SUGCT,C16orf45,VTI1A,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,RPGRIP1L,NDUFB3,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,LRRC75A-AS1,ZNF480,EIF3J,CCNDBP1,MEF2D,GSTCD,SLC35D1,DSP,NUDT15,VPS53,MAT2A,FBXL5,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,PTGS1,ZNF710,FBXL19,ACTR3B,SAMD4A,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,UQCC1,MTMR1,CYP24A1,CUL7,TRIM16,AAMDC,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,HNRNPLL,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,DBN1,DSC3,FMNL3,RBCK1,AEBP2,ATF4,MIOS,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,KRTCAP2,KCNH2,ODC1,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,NKD2,MAPK8IP3,FAN1,SMAD7,LAMTOR3,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,WNT16,PNPLA3,LRSAM1,NIPSNAP1,WARS2,USP49,IFT43,HAUS6,SETD2,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,SNX24,CASS4,SIL1,DTD1,PTP4A2,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,NTSR1,RPS29,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,RADIL,PPP1R9A,ZNF121,URB1,FDX1,ANKRD13A,NRF1,IDI1,NUP133,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,ARHGAP17,AKAP8L,SSFA2,TEX19,RAB7A,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,HSPB8,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,NIFK,ESCO1,MINK1,KIZ,MCM10,AUH,HM13,RFX1,AGO2,ESRG,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,CPNE7,POLR1B,C12orf4,SNAPC5,PCSK6,TRNP1,AP4S1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,DKK1,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,VSNL1,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,SPOP,OSBPL1A,DOT1L,GZF1,GNAI1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,HSPBAP1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,XPNPEP1,NRP1,BMI1,BLMH,RFXAP,ZMAT3,NMD3,PRPF38B,C9orf78,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,CENPB,DPM3,CRACR2A,SSR4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,PRIM2,RREB1,PCCA,RDH10,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,NELFA,EHBP1,SLC26A11,MTR,ZNF850,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,PLEK2,CORO6,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,RMDN3,TTC3,CMPK1,ARL14EP,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,TRAF3,TBXA2R,XRCC4,SETD6,MID1,VWA8,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,INPP1,PHLDA2,SFR1,ABL1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,LYRM4,EIF3C,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DEAF1,DTNB,TNK2,SESN2,FBXW4,ZNF195,SKAP2,SIRT6,ITPA,TFPI,ARRDC3,MINA,TMEM216,KSR2,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,MPC1,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,ZNF354A,WDR27,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,HSD17B14,ZNF629,MSI2,HBG2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,EIF2A,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,APBB3,SYCP2L,BICD1,FSCN1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,AGO3,N4BP2L2,NR2C2AP,DMXL2,TCF12,SNX27,CHMP2A,PSTPIP2,CEMIP,PIGH,SMARCA4,PBX1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,CBR4,SNTG2,FHIT,ADCK4,VCL,TMEM120B,UTP4,GNG5,C6orf89,AUP1,MAML3,NARS2,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,DUS3L,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,WDR73,DUSP19,FKBP5,NFRKB,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,IGF2BP2,WDR26,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,DCTN4,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,SULT4A1,METTL23,ASAP3,ZNF324B,SCMH1,PDE2A,PEAK1,TMEM187,EIF5B,CTIF,ZNF221,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,ASCC1,WDR74,CSPP1,CHAC1,HLTF,NT5C3A,COA1,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RASSF3,RABGAP1L,FAAH2,PDS5B,WIZ,FNIP2,ZNF148,HRG,LYRM5,FXN,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,MCL1,DCUN1D5,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,FIS1,FIP1L1,RBP1,MEF2C,LPP,CARS,TNNC1,HERC2,EP400,TRIP6,SLK,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,CLINT1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,MAP3K12,AGL,COQ3,FMNL2,TOMM34,SERBP1,EMC10,HMGCR,FADS1,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,CPT1A,MBNL2,ONECUT2,ABCF1,ZNF655,NCDN,ZNF783,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,GPN1,SENP3,CNOT6,WDR33,COG5,SPRED2,FAM208B,DNM3,ABCA3,MAP2K5,ZNF516,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,TMEM150C,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,NT5C,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ARHGEF10,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,NOL4L,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,GATC,TMSB10,ARHGAP1,SOX6,HNRNPM,LYPLA2,DIS3L2,ULBP1,NUDC,DDHD1,FAM98A,FGF9,FBXO17,CEP83,CLYBL,POLK,CEP295,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,ZNF467,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,ETFDH,RARS,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLC25A19,PTPN4,GPAM,PSAP,IGBP1,DOCK6,NUDT22,ANAPC4,CORO2B,KDM4C,SRM,BCAS4,GPBP1L1,PPARGC1B,TFIP11,POLR1A,HECTD3,NREP,CSNK2A1,RNF43,TMEM132A,TTI1,COX10,SEC16A,BIRC2,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,TMPO,SF3A1,CDC37,FLNC,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,HARS,ZNF414,BAZ2A,KATNAL1,GDPD1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,MSRA,ZNF622,TP53BP1,PER1,EEFSEC,FAM206A,CCDC146,TNFRSF1A,RAD51B,SGSM2,DLX2,C2CD5,CHMP4C,XYLB,SARS,TTN,AOC3,OXNAD1,MCM6,PGPEP1,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,RLF,DNAH1,RNF40,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NT5E,NAA38,TRAPPC9,CAMKK2,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,PELP1,RPAIN,KDM1A,METTL16,CAD,ZBTB21,DUS4L,TMEM94,UBR1,DNAJB6,FSIP2,ARMC5,IKBKB,ZDHHC6,HIRIP3,RNF2,ETF1,ZFP37,HIBCH,CORO1A,AKNAD1,PRMT3,CASP10,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,TUBA1A,DDX41,NARS,GLTSCR2,C1QTNF1,CPOX,AKAP13,ENC1,NUP214,PUM3,TMEM186,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,TIMM17A,ZNF333,ZNF436,PUS1,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,PKIB,UNC13D,MIF4GD,MAP3K13,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,PRICKLE2,HIST2H3D,DDX31,FBXO31,CD44,PCK2,HSD17B12,FAM71E1,GINS3,ZNF654,ZMYM5,TPM4,DHX34,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,NEU1,ARMC3,ZRANB3,MKX,POLR3G,CENPP,TPD52L2,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,POLB,CGN,PRDX6,PRKAB2,DDX19A,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,VPS52,ME1,CEP135,MEIS3,TRMT10A,FUT11,SEH1L,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,TCEB3,CUX1,DESI1,HSH2D,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,ZNF81,DNAH2,CCNB1IP1,TXN2,SYNPO,PTPN14,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,AK6,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,ENTPD5,ASAP1,COPS3,ATIC,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,EPRS,KIDINS220,SERF2,NSF,PMEPA1,UBAP1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,CCDC58,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,KLHL18,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,PDE3A,PAIP2,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,PLEKHA4,NAA35,RFC4,CFAP221,RFC3,PDK1,MTIF2,SFXN4,WDPCP,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,CPED1,VDR,TAMM41,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,CEP126,LIAS,MON2,IKBKAP,NOL3,GDPD5,FOXO3,MAD2L2,TMCO6,NEDD4,DCTPP1,ZNF239,ZNF483,RGS17,COMMD9,PTRF,LRP2BP,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,MAP3K14,LARP4B,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,PTK2,APTX,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,FBXO21,KLHL22,ZDHHC11,COL26A1,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,CERS5,FANCD2,RCHY1,PLOD1,ZNF107,BCOR,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ANAPC1,RAP1A,YLPM1,ATG3,ZNHIT6,ANAPC10,RELB,HYAL1,IPP,JOSD1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TRIM14,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,CMIP,ZNF680,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,SERGEF,CHAF1A,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,UBE3D,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,BBIP1,GALNT10,COPS6,ZNF397,NOCT,DMTF1,EMSY,TNRC6A,LDAH,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,GLTP,NRIP1,N4BP2,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,BLOC1S4,C19orf70,DNAH14,ISG15,MYBBP1A,ATAD5,INTS5,SDCCAG8,RRAGA,HK2,EXOC4,PTRH2,ZFP90,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,SLC5A5,MYO7A,FAM210A,SLC9B2,CSTA,UBTD2,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,ECHDC1,KLHL24,TNIK,DNAJA4,SULT1C2,OXLD1,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,PPP1R1C,MFSD10,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,IL17RE,GART,CTNNBL1,HAS3,TANK,KDELC1,SHMT2,TTC17,UTS2,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,PREPL,ZAK,MMP16,ARHGAP27,HRH1 |
| 1.989e-47 | -107.53 | nuclear part | cellular component | GO:0044428 | 3794 | 757 | 17570 | 2233 |
ASCC1,THOC5,WDR74,MRPL10,NAT10,HLTF,CCNL2,NUP160,CIAPIN1,NOS1AP,SKI,NEK6,FAM222B,SREBF2,ZFHX3,IKZF5,NSRP1,MAD1L1,PDS5B,ZNF148,FNIP2,KDM5C,SRRM2,ZNRD1,FTSJ3,CDK6,HMBOX1,RNMT,GNL3,EHMT1,NFIA,WDHD1,MCL1,SHISA5,MCM2,RBM28,STOML2,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,FIP1L1,RBP1,MEF2C,BANP,HERC2,TNNC1,EP400,KHDRBS1,SIRT7,PIK3R4,RSF1,PDCD7,CLINT1,PARN,CDC73,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,TNPO3,ANP32B,GEMIN4,NOC3L,PRMT5,PABPC1,TOMM34,MYB,NOM1,GATAD2B,GTF2H3,WDR61,STAG1,MYO10,RB1CC1,ARID5B,IDH3G,USP10,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,TSR1,KPNA1,GTF2A1,EHMT2,TRAP1,LEMD3,CDK9,GPN1,SENP3,WDR33,COG5,FAM208B,DDX18,GTF2H2C,PAFAH1B1,NPAS2,MYH9,ISG20L2,NUP43,SAFB2,ZMAT2,HSPA1A,RPP30,PRKD3,BCAS2,ACD,ERI1,WAC,ATRIP,INTS12,MSH4,MGLL,ZC3H3,LSM10,PMS1,KMT2D,GARS,STAMBP,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,CCNDBP1,PES1,TAF2,CDC16,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,CEP170,MAPT,HMGA2,NOL4L,SHQ1,XPC,SF3A3,ID2,JMJD6,AKT1S1,IP6K2,TRIM22,BHLHE40,ZNF691,RSRC1,PSMF1,MBNL1,POM121,KRI1,TADA3,SNW1,POLR3D,SUV39H2,TAF3,NOP16,PTGS1,PNMA1,SOX6,HNRNPM,DIS3L2,NUDC,VPS37A,DDX24,POLK,ZC3H18,CCDC113,FOXC1,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,POLE2,ARID3B,ACOX1,AEN,NUDT22,ANAPC4,KDM4C,CYP24A1,CUL7,TRIM16,PPARGC1B,TFIP11,WDR13,POLR1A,CSNK2A1,RNF43,NLE1,GIT2,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,DHX33,TRMU,NCKIPSD,XRCC2,ANKRD11,UBAP2L,RAN,POLE3,ZMYM2,TMPO,SF3A1,METTL1,CHD9,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,HSPA5,MED27,NOL6,COL4A3BP,PSMG1,SUMO3,BRCA1,KCNH2,LSG1,CXADR,MLLT10,MSRA,ZNF622,TCF7L1,TP53BP1,CHD3,FAM206A,ARL4A,E2F4,RAD51B,PRPF4,TSEN2,MAGI1,TTN,MCM6,FOXO1,SMAD7,FAN1,ARID1B,RNF40,SUB1,MBD2,VPS72,PPIL2,GTF2H1,CTR9,TIMELESS,ICE2,TLE3,HOMER2,HAUS6,SETD2,UTP15,RNH1,SUPT5H,TCF7L2,NR2F1,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,SNAP23,TBPL1,PPP1R12B,BCCIP,USP7,SART1,ID1,PAPD4,ARID2,RBFOX2,PPP2R2A,RSL1D1,TNKS1BP1,PELP1,RPAIN,URB1,KDM1A,CAD,NRF1,TMEM94,NUP133,DNAJB6,HIRIP3,RNF2,SPIDR,IPO11,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,AKAP8L,DDX41,GLTSCR2,ENC1,NUP214,PUM3,USP36,EXO1,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,KLF4,ZNF436,INTS9,HSPB8,PUS1,MED20,FAHD1,PPIL3,MUTYH,NIFK,ESCO1,MCM10,MIF4GD,RFX1,AGO2,MAP1S,APRT,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,PTPN2,FAM50A,SURF2,ANXA7,ZNF561,CWC27,PRICKLE2,HIST2H3D,DDX31,POLR1B,SNAPC5,TRNP1,GINS3,SMARCAD1,TOP3A,FERMT2,C11orf49,RANGAP1,YIPF3,HIST1H4J,PIK3CB,POLR3A,ZRANB3,CENPP,POLR3G,NOL10,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,RBPJ,TAF12,XPO6,POLB,CUL4A,PRKAB2,DDX19A,PLRG1,TMEM109,PRKCA,UBR5,LPIN1,MGA,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,SEH1L,DPF3,SNU13,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,SUPT20H,HIST1H2BL,SON,MAK16,SAP30BP,CLNS1A,OSBPL1A,SPOP,GZF1,DOT1L,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,CCNB1IP1,TXN2,BMI1,ZMAT3,NMD3,PTPN14,PRPF38B,WDR75,C9orf78,DROSHA,EGR1,JUP,CELSR1,ZHX3,PRPF31,AK6,GTF2IRD1,PID1,CRACR2A,PRPF39,CHD5,HR,ZNF586,USPL1,COPS3,MYC,GTF3C3,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,ANAPC13,SIGMAR1,POLA1,RAP1GAP2,ARID1A,NELFA,PLCB1,SLC26A11,PHF6,ASCC3,ALKBH3,HIF1A,PMEPA1,SRP68,SPEN,MED15,PURB,NCOR1,CNDP2,DHCR7,SMYD3,AMOTL1,LIN28B,URB2,UROD,NDUFB5,OLA1,SPATS2L,POP5,FOSL2,HNRNPA3,RING1,TRIM66,NOP56,TERF2IP,PHC2,CHD7,DECR1,SLX4,KDM2A,PPID,UCHL5,GLYR1,TTC3,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,ZBTB25,SNCA,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,H2AFX,MDN1,PDCD11,NOLC1,XRCC4,NCOR2,UTP14A,MRI1,TCF3,NFX1,RTN4,MLH1,OPA1,NOL3,IKBKAP,RPS6KA5,FOXO3,MAD2L2,SFR1,ABL1,PTRF,COPS7B,UPF2,CELF1,EXOSC4,S100A14,LARP4B,NAV3,CLK2,PXN,APEX1,WDFY3,WDR18,BMS1,APTX,OASL,NOP58,POLR2A,RETSAT,DDX50,HNRNPH3,ORC5,ATM,ADK,IPO4,DDIT3,KAT6A,FEM1C,UBN1,ATRX,NF1,KMT2E,CERS5,FANCD2,RCHY1,PPIL1,BCOR,SIRT2,SNAPC4,CUTC,SMARCB1,DST,ANAPC1,KANSL1,YLPM1,JAZF1,SLC39A7,ANAPC11,ANAPC10,RELB,ZEB1,GPATCH1,POLR3B,HCFC2,OGG1,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,DEAF1,TXLNG,SKAP2,SIRT6,MINA,HDAC8,COTL1,ZSCAN2,SOX4,KMT2C,CHAF1A,TAF9B,GEMIN5,UBTF,PAF1,EPN2,EIF4ENIF1,SUFU,GATA6,HLCS,DNAJC1,CC2D1B,PQBP1,CRCP,EME1,COPS6,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,ZCCHC8,TAF1,PAX2,DPF2,MED13L,XPO7,CMTM3,NAMPT,TOX4,CEP164,ELL,WDR27,ATXN2,BANF1,BUD31,NRIP1,ZCCHC7,POLR1E,CPSF3L,RANBP6,TRA2A,XPO5,JMJD1C,ELP3,WBSCR22,LIG4,PSMA1,ISG15,UBE2E1,POP1,SYCP2L,MYBBP1A,INTS5,FDPS,PFDN2,TBL1X,NR2C2AP,TCF12,SNX27,ASH1L,SMARCA4,PBX1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,BRE,NVL,CPSF3,TMEM120B,UTP4,C6orf89,MAML3,HN1,ACSL5,PTBP2,PARP2,GRHL3,POU2F1,ATXN1,TOR1AIP2,DKC1,UBR4,S100A16,ARMC4,ZC3H12A,IKZF4,KPNA3,HNRNPR,COPS5,ARNTL,FKBP5,HEATR1,NFRKB,TMEM33,DNAJC2,TNIK,CMTM8,H2AFJ,DBF4,PPHLN1,MED18,ATF7IP,WDR26,CTNNBL1,ERI3,FBL,AMOT,MICAL3,TOP1,RPS6KB2,KDM6B,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,SCMH1,MEN1,PEAK1,SYMPK,HSPA1B,RERE,GADD45A,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,POLR1C,TATDN1,ARHGAP27,HRH1 |
| 1.366e-46 | -105.61 | intracellular | cellular component | GO:0005622 | 13688 | 1985 | 17570 | 2233 |
PTP4A1,ARHGAP26,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,HMOX2,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,UPP1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,KRBOX4,WDHD1,C5AR1,SHISA5,MCM2,ZNF197,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,DIRAS1,RUNX1,TPM1,VASH2,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TRIO,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,CHN1,RBM20,CNST,UBE3A,DHX37,APLF,MED24,TNPO3,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,ANGPT2,MYB,NOM1,RABEPK,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,SUGCT,C16orf45,VTI1A,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,RPGRIP1L,NDUFB3,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,LRRC75A-AS1,PI4KAP2,ZNF480,EIF3J,CCNDBP1,KCNH3,MEF2D,GSTCD,SLC35D1,DSP,NUDT15,VPS53,MAT2A,FBXL5,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,RAPGEFL1,PTGS1,ZNF710,FBXL19,ACTR3B,SAMD4A,PNMA1,RPL22L1,SPTAN1,TTPAL,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,UQCC1,MTMR1,CYP24A1,CUL7,TRIM16,AAMDC,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,HNRNPLL,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,DBN1,DSC3,FMNL3,RBCK1,AEBP2,ATF4,MIOS,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,KRTCAP2,KCNH2,ODC1,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,NKD2,MAPK8IP3,FAN1,SMAD7,LAMTOR3,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,WNT16,PNPLA3,LRSAM1,NIPSNAP1,WARS2,USP49,IFT43,HAUS6,SETD2,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,SNX24,CASS4,SIL1,DTD1,PTP4A2,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,NTSR1,RPS29,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PAG1,PPP1R9A,ZNF121,URB1,PLXNB1,FDX1,ANKRD13A,NRF1,IDI1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,ARHGAP17,AKAP8L,SSFA2,TEX19,RAB7A,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,HSPB8,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,NIFK,ESCO1,MINK1,KIZ,MCM10,AUH,HM13,RFX1,AGO2,ESRG,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,CPNE7,POLR1B,C12orf4,SNAPC5,PCSK6,TRNP1,AP4S1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,DKK1,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,NBEAL1,PRKCA,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,VSNL1,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,SPOP,OSBPL1A,DOT1L,GZF1,GNAI1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,HSPBAP1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,XPNPEP1,NRP1,BMI1,BLMH,RFXAP,ZMAT3,NMD3,PRPF38B,C9orf78,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,CENPB,DPM3,CRACR2A,SSR4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,PRIM2,RREB1,PCCA,RDH10,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,NELFA,EHBP1,SLC26A11,MTR,ZNF850,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,PLEK2,CORO6,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,RMDN3,TTC3,CMPK1,ARL14EP,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,TRAF3,TBXA2R,XRCC4,SETD6,MID1,VWA8,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,INPP1,PHLDA2,SFR1,ABL1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,LYRM4,EIF3C,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DEAF1,DTNB,TNK2,SESN2,FBXW4,ZNF195,SKAP2,SIRT6,ITPA,TFPI,ARRDC3,MINA,TMEM216,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,MPC1,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,ZNF354A,WDR27,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,HSD17B14,ZNF629,MSI2,HBG2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,EIF2A,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,APBB3,SYCP2L,BICD1,FSCN1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,AGO3,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,PSTPIP2,CEMIP,TNXB,PIGH,SMARCA4,PBX1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,CBR4,SNTG2,FHIT,ADCK4,VCL,TMEM120B,UTP4,GNG5,C6orf89,AUP1,MAML3,NARS2,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,DUS3L,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,WDR73,DUSP19,FKBP5,NFRKB,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,IGF2BP2,WDR26,PIP4K2A,BMP6,FAM49A,MFHAS1,GFM2,PEX7,SEC24C,DCTN4,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,SLC6A16,PPP1R9B,DNMBP,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,SULT4A1,METTL23,ASAP3,ZNF324B,SCMH1,PDE2A,PEAK1,TMEM187,EIF5B,CTIF,ZNF221,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,ASCC1,WDR74,CSPP1,CHAC1,HLTF,NT5C3A,COA1,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RASSF3,RABGAP1L,FAAH2,PDS5B,WIZ,FNIP2,ZNF148,HRG,LYRM5,FXN,AVEN,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,MCL1,PLEKHM3,DCUN1D5,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,FIS1,FIP1L1,RBP1,MEF2C,LPP,CARS,TNNC1,HERC2,EP400,TRIP6,SLK,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,CLINT1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,MAP3K12,AGL,COQ3,FMNL2,TOMM34,SERBP1,EMC10,HMGCR,FADS1,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,CPT1A,MBNL2,ONECUT2,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,GPN1,SENP3,CNOT6,WDR33,COG5,SPRED2,FAM208B,DNM3,ABCA3,MAP2K5,ZNF516,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,TMEM150C,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,NT5C,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ARHGEF10,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,NOL4L,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,GATC,TMSB10,ARHGAP1,SOX6,HNRNPM,LYPLA2,DIS3L2,ULBP1,NUDC,DDHD1,FAM98A,FGF9,FBXO17,CEP83,CLYBL,POLK,CEP295,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,ETFDH,RARS,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLC25A19,PTPN4,GPAM,PSAP,IGBP1,DOCK6,NUDT22,ANAPC4,CORO2B,KDM4C,SRM,BCAS4,GPBP1L1,PPARGC1B,TFIP11,POLR1A,HECTD3,NREP,CSNK2A1,RNF43,TMEM132A,TTI1,COX10,SEC16A,BIRC2,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,TMPO,SF3A1,CDC37,FLNC,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,HARS,ZNF414,BAZ2A,KATNAL1,GDPD1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,FAM206A,EEFSEC,CCDC146,TNFRSF1A,RAD51B,SGSM2,DLX2,C2CD5,CHMP4C,XYLB,SARS,TTN,AOC3,OXNAD1,PGPEP1,MCM6,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,RNF40,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NT5E,NAA38,TRAPPC9,CAMKK2,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,RBFOX2,LPCAT2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,PELP1,RPAIN,KDM1A,METTL16,CAD,ZBTB21,DUS4L,TMEM94,UBR1,DNAJB6,FSIP2,ARMC5,IKBKB,ZDHHC6,HIRIP3,ANO8,RNF2,ETF1,ZFP37,HIBCH,CORO1A,AKNAD1,PRMT3,CASP10,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,TUBA1A,DDX41,NARS,GLTSCR2,C1QTNF1,CPOX,AKAP13,ENC1,ARL5B,NUP214,PUM3,TMEM186,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,TIMM17A,ZNF333,ZNF436,PUS1,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,PKIB,UNC13D,MIF4GD,MAP3K13,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,PRICKLE2,HIST2H3D,DDX31,FBXO31,CD44,PCK2,HSD17B12,FAM71E1,GINS3,ZNF654,ZMYM5,TPM4,DHX34,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,NEU1,ARMC3,ZRANB3,MKX,POLR3G,CENPP,TPD52L2,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,MIPOL1,GCSH,POLB,MYCBP2,CGN,PRDX6,PRKAB2,DDX19A,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,VPS52,ME1,CEP135,MEIS3,TRMT10A,FUT11,SEH1L,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,TCEB3,CUX1,DESI1,HSH2D,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,ZNF81,VPS13D,DNAH2,CCNB1IP1,TXN2,SYNPO,PTPN14,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,AK6,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,ENTPD5,ASAP1,COPS3,ATIC,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,EPRS,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,CCDC58,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,KLHL18,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,PDE3A,PAIP2,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,PLEKHA4,NAA35,RFC4,CFAP221,RFC3,PDK1,MTIF2,SFXN4,WDPCP,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,CPED1,TAMM41,VDR,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,CEP126,LIAS,MON2,IKBKAP,NOL3,GDPD5,FOXO3,MAD2L2,TMCO6,NEDD4,DCTPP1,ZNF239,ZNF483,RGS17,COMMD9,PTRF,LRP2BP,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,MAP3K14,LARP4B,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,PTK2,APTX,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,FBXO21,KLHL22,ZDHHC11,COL26A1,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,CERS5,FANCD2,RCHY1,PLOD1,ZNF107,BCOR,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ANAPC1,RAP1A,YLPM1,ATG3,ZNHIT6,ANAPC10,RELB,HYAL1,IPP,JOSD1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TRIM14,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,CMIP,ZNF680,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,SERGEF,CHAF1A,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,UBE3D,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,BBIP1,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,TNRC6A,LDAH,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,GLTP,NRIP1,N4BP2,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,BLOC1S4,C19orf70,DNAH14,ISG15,MYBBP1A,ATAD5,INTS5,SDCCAG8,RRAGA,HK2,EXOC4,PTRH2,ZFP90,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,SLC5A5,MYO7A,FAM210A,SLC9B2,CSTA,UBTD2,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,ECHDC1,KLHL24,TNIK,DNAJA4,SH2D3A,SULT1C2,OXLD1,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,PPP1R1C,MFSD10,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,IL17RE,GART,CTNNBL1,HAS3,TANK,KDELC1,SHMT2,TTC17,UTS2,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,PREPL,ZAK,MMP16,ARHGAP27,HRH1 |
| 4.037e-44 | -99.92 | intracellular organelle | cellular component | GO:0043229 | 11578 | 1753 | 17570 | 2233 |
PTP4A1,ARHGAP26,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,HMOX2,ABHD6,CIAPIN1,SKI,ZNF37A,PDZD2,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,RNMT,LIMA1,EHMT1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,MCM2,ZNF197,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,RUNX1,TPM1,SLC25A26,ZNF532,BANP,EPM2AIP1,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,RBM20,CNST,UBE3A,DHX37,APLF,MED24,TNPO3,GEMIN4,MRPL21,PABPC1,ANGPT2,MYB,NOM1,RABEPK,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,NME7,PDLIM1,RPL28,EHMT2,TRAP1,CCDC85B,KIAA0196,PDLIM5,SRP14,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,SUGCT,C16orf45,VTI1A,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,RPGRIP1L,NDUFB3,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,LRRC75A-AS1,ZNF480,CCNDBP1,MEF2D,SLC35D1,DSP,VPS53,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,ANXA5,PTGS1,ZNF710,ACTR3B,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,UBC,ANXA1,MRPL36,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,UQCC1,CYP24A1,CUL7,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,HNRNPLL,MAP2K3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,DBN1,AEBP2,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,PSMG1,SUMO3,KRTCAP2,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,NKD2,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,PNPLA3,NIPSNAP1,WARS2,IFT43,USP49,HAUS6,SETD2,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,SNX24,CASS4,SIL1,DTD1,PTP4A2,SH3PXD2A,BCCIP,USP7,SART1,ID1,OLFM2,SUCLG1,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,RADIL,PPP1R9A,URB1,ZNF121,FDX1,ANKRD13A,NRF1,IDI1,NUP133,MYH15,BCAP29,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,RAB7A,VIM,CA5B,ZNF251,TJAP1,EXO1,IFT81,KLF4,INTS9,HSPB8,MED20,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,NIFK,ESCO1,MINK1,KIZ,MCM10,HM13,AUH,RFX1,AGO2,ESRG,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,YIPF3,EXOG,PALLD,POLR3A,DKK1,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,NRP1,BLMH,BMI1,RFXAP,ZMAT3,NMD3,PRPF38B,C9orf78,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,CENPB,DPM3,CRACR2A,SSR4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAP1GAP2,RAP1B,ARID1A,NELFA,SLC26A11,ZNF850,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,PLEK2,CORO6,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,PPID,LPIN2,MRPS27,DTNBP1,TTC3,RMDN3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,IFT140,TRAF3,TBXA2R,SETD6,XRCC4,MID1,VWA8,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,SFR1,ABL1,NEBL,ELP5,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,LYRM4,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DEAF1,TNK2,SESN2,ZNF195,SKAP2,SIRT6,TFPI,ARRDC3,MINA,TMEM216,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,MPC1,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,ZCCHC8,VTA1,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,ZNF354A,WDR27,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,ZNF629,ZNF234,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,SYT1,HERPUD1,UBE2E1,MGAT2,POP1,APBB3,SYCP2L,BICD1,FSCN1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,AGO3,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,PSTPIP2,CEMIP,PIGH,SMARCA4,PBX1,TBCCD1,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,CBR4,SNTG2,FHIT,ADCK4,VCL,TMEM120B,UTP4,C6orf89,AUP1,MAML3,NARS2,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,WDR73,FKBP5,NFRKB,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,IGF2BP2,WDR26,PIP4K2A,GFM2,PEX7,SEC24C,DCTN4,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,ZNF324B,SCMH1,PDE2A,PEAK1,TMEM187,EIF5B,ZNF221,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,ASCC1,WDR74,CSPP1,HLTF,CHAC1,NT5C3A,COA1,NUP160,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RABGAP1L,RASSF3,FAAH2,PDS5B,WIZ,FNIP2,ZNF148,HRG,LYRM5,FXN,CDK6,WLS,GNL3,RFX2,MSRB3,AKAP12,MCL1,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,LPP,MEF2C,TNNC1,HERC2,EP400,TRIP6,KHDRBS1,SIRT7,PRAF2,PLA2G12A,RSF1,CLINT1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,COQ3,AGL,TOMM34,SERBP1,EMC10,HMGCR,FADS1,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,NCDN,ZNF783,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,GPN1,SENP3,CNOT6,WDR33,COG5,SPRED2,FAM208B,DNM3,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,BTBD2,NPAS2,ATP6V1A,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,TMEM150C,PRKD3,BCAS2,ABCA12,ZKSCAN1,ERI1,FMNL1,ATRIP,NT5C,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ARHGEF10,ATP6V0A1,TTC28,FKBP3,FGFR1,PES1,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,NOL4L,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,GATC,TMSB10,SOX6,HNRNPM,DIS3L2,ULBP1,NUDC,CEP83,CLYBL,POLK,CEP295,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,ZNF467,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,RARS,ETFDH,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,ANAPC4,KDM4C,CORO2B,GPBP1L1,PPARGC1B,TFIP11,POLR1A,NREP,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,GIT2,BIRC2,ABL2,DHX33,MARVELD2,TRMU,XRCC2,UBAP2L,ZNF85,POLE3,RAN,ETV1,MPST,SF3A1,TMPO,FLNC,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,ZNF414,BAZ2A,HARS,KATNAL1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,MSRA,ZNF622,TP53BP1,PER1,EEFSEC,FAM206A,CCDC146,TNFRSF1A,RAD51B,DLX2,C2CD5,CHMP4C,AOC3,OXNAD1,TTN,SARS,MCM6,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,RLF,DNAH1,RNF40,ABCA5,SAMD11,PPIL2,GTF2H1,TIMELESS,ALDH18A1,NAA38,TRAPPC9,CAMKK2,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,PPP1R12B,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,NDUFA5,CYLD,RBFOX2,LPCAT2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,METTL16,CAD,ZBTB21,TMEM94,DNAJB6,FSIP2,ZDHHC6,IKBKB,HIRIP3,RNF2,ETF1,ZFP37,HIBCH,CORO1A,PRMT3,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,TUBA1A,DDX41,NARS,GLTSCR2,CPOX,AKAP13,ENC1,NUP214,USP36,TMEM186,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,RBBP8,SIX5,TIMM17A,ZNF333,CLEC16A,ZNF436,PUS1,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,PKIB,UNC13D,MIF4GD,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,HIST2H3D,PRICKLE2,DDX31,FBXO31,CD44,PCK2,HSD17B12,FAM71E1,GINS3,ZNF654,ZMYM5,TPM4,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,NEU1,ZRANB3,MKX,POLR3G,CENPP,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,POLB,CGN,PRDX6,PRKAB2,DDX19A,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,RPS16,PAK1IP1,RNF111,VPS52,ME1,CEP135,MEIS3,TRMT10A,FUT11,SEH1L,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,DESI1,HSH2D,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,ZNF81,DNAH2,CCNB1IP1,TXN2,SYNPO,PTPN14,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,AK6,OPHN1,GTF2IRD1,PID1,CCDC47,CHD5,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,ENTPD5,COPS3,ATIC,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIGMAR1,POLA1,KIAA0586,PTPN12,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,CCDC58,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,RFC4,CFAP221,RFC3,PDK1,MTIF2,SFXN4,WDPCP,DLG4,MED16,PNN,POLG2,DHX57,CPED1,TAMM41,VDR,YIPF2,DNAJA3,ZNF236,H2AFX,ALKBH1,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,CEP126,LIAS,MON2,IKBKAP,NOL3,GDPD5,FOXO3,MAD2L2,TMCO6,NEDD4,ZNF239,ZNF483,RGS17,COMMD9,PTRF,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,LARP4B,NT5M,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,PTK2,APTX,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,KLHL22,ZDHHC11,COL26A1,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,STK4,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,CERS5,FANCD2,RCHY1,PLOD1,ZNF107,BCOR,SIRT2,SNAPC4,CUTC,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ANAPC1,RAP1A,YLPM1,ANAPC10,RELB,HYAL1,IPP,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,CMIP,ZNF680,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,SERGEF,CHAF1A,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,TNRC6A,LDAH,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,XPO7,C11orf54,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,NRIP1,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,C19orf70,DNAH14,ISG15,MYBBP1A,ATAD5,INTS5,SDCCAG8,RRAGA,HK2,PTRH2,ZFP90,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,SLC5A5,MYO7A,FAM210A,SLC9B2,CSTA,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,BRE,CAMTA2,RPS6KL1,ZNF142,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,WARS,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,TNIK,OXLD1,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,MFSD10,HDDC2,SFI1,MAN1A1,MRPS11,CTNNBL1,KDELC1,SHMT2,TTC17,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,PREPL,ZAK,MMP16,ARHGAP27,HRH1 |
| 5.157e-43 | -97.37 | nuclear lumen | cellular component | GO:0031981 | 3428 | 688 | 17570 | 2233 |
ASCC1,THOC5,WDR74,MRPL10,NAT10,HLTF,CCNL2,CIAPIN1,SKI,NEK6,FAM222B,SREBF2,ZFHX3,IKZF5,NSRP1,PDS5B,ZNF148,FNIP2,KDM5C,SRRM2,ZNRD1,FTSJ3,CDK6,HMBOX1,RNMT,GNL3,EHMT1,NFIA,WDHD1,MCL1,MCM2,RBM28,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,FIP1L1,RBP1,MEF2C,BANP,HERC2,TNNC1,EP400,KHDRBS1,SIRT7,RSF1,PDCD7,CLINT1,PARN,CDC73,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,ANP32B,GEMIN4,NOC3L,PRMT5,TOMM34,MYB,NOM1,GATAD2B,GTF2H3,WDR61,STAG1,MYO10,ARID5B,IDH3G,USP10,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,TSR1,KPNA1,GTF2A1,EHMT2,TRAP1,CDK9,GPN1,SENP3,WDR33,COG5,FAM208B,DDX18,NPAS2,ISG20L2,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ACD,ERI1,WAC,ATRIP,INTS12,MSH4,MGLL,ZC3H3,LSM10,KMT2D,GARS,STAMBP,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,CCNDBP1,PES1,TAF2,CDC16,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,ANKS1A,YEATS2,MAPT,HMGA2,NOL4L,SHQ1,XPC,SF3A3,ID2,JMJD6,AKT1S1,IP6K2,TRIM22,BHLHE40,ZNF691,RSRC1,PSMF1,MBNL1,KRI1,TADA3,SNW1,POLR3D,SUV39H2,TAF3,NOP16,PNMA1,SOX6,HNRNPM,DIS3L2,NUDC,VPS37A,DDX24,POLK,ZC3H18,CCDC113,FOXC1,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,POLE2,ARID3B,ACOX1,AEN,NUDT22,ANAPC4,KDM4C,CYP24A1,CUL7,TRIM16,PPARGC1B,TFIP11,WDR13,POLR1A,CSNK2A1,NLE1,GIT2,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,ANKRD11,UBAP2L,RAN,POLE3,ZMYM2,SF3A1,METTL1,CHD9,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,MED27,NOL6,COL4A3BP,PSMG1,SUMO3,BRCA1,LSG1,CXADR,MLLT10,MSRA,ZNF622,TCF7L1,TP53BP1,CHD3,FAM206A,ARL4A,E2F4,RAD51B,PRPF4,TSEN2,MAGI1,TTN,MCM6,FOXO1,SMAD7,FAN1,ARID1B,RNF40,SUB1,MBD2,VPS72,PPIL2,GTF2H1,CTR9,TIMELESS,ICE2,TLE3,HOMER2,SETD2,HAUS6,UTP15,RNH1,SUPT5H,TCF7L2,NR2F1,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,SNAP23,TBPL1,PPP1R12B,USP7,SART1,ID1,ARID2,RBFOX2,PPP2R2A,RSL1D1,TNKS1BP1,PELP1,URB1,RPAIN,KDM1A,CAD,NRF1,TMEM94,DNAJB6,HIRIP3,RNF2,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,AKAP8L,GLTSCR2,ENC1,NUP214,PUM3,USP36,EXO1,SMAD3,RBBP8,SIX5,TIMM17A,KLF4,ZNF436,INTS9,HSPB8,PUS1,MED20,FAHD1,MUTYH,NIFK,ESCO1,MCM10,MIF4GD,RFX1,AGO2,MAP1S,APRT,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,PTPN2,FAM50A,SURF2,ZNF561,HIST2H3D,DDX31,POLR1B,SNAPC5,TRNP1,GINS3,SMARCAD1,TOP3A,FERMT2,C11orf49,YIPF3,HIST1H4J,PIK3CB,POLR3A,ZRANB3,POLR3G,CENPP,NOL10,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,RBPJ,TAF12,XPO6,POLB,CUL4A,PRKAB2,PLRG1,PRKCA,UBR5,LPIN1,MGA,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,SNU13,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,SUPT20H,HIST1H2BL,SON,MAK16,SAP30BP,CLNS1A,OSBPL1A,SPOP,GZF1,DOT1L,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,CCNB1IP1,TXN2,BMI1,ZMAT3,NMD3,PTPN14,C9orf78,WDR75,DROSHA,CELSR1,EGR1,ZHX3,PRPF31,AK6,PID1,GTF2IRD1,CRACR2A,CHD5,HR,ZNF586,USPL1,COPS3,MYC,GTF3C3,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,POLA1,ARID1A,NELFA,PLCB1,SLC26A11,PHF6,ASCC3,ALKBH3,HIF1A,PMEPA1,SRP68,SPEN,MED15,PURB,NCOR1,CNDP2,SMYD3,LIN28B,URB2,UROD,NDUFB5,OLA1,SPATS2L,POP5,FOSL2,HNRNPA3,RING1,TRIM66,NOP56,PHC2,TERF2IP,CHD7,DECR1,SLX4,KDM2A,PPID,UCHL5,GLYR1,TTC3,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,ZBTB25,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,H2AFX,MDN1,PDCD11,XRCC4,NOLC1,NCOR2,UTP14A,MRI1,TCF3,NFX1,MLH1,OPA1,NOL3,IKBKAP,RPS6KA5,FOXO3,MAD2L2,SFR1,ABL1,PTRF,COPS7B,CELF1,EXOSC4,S100A14,LARP4B,CLK2,PXN,APEX1,WDFY3,WDR18,BMS1,APTX,OASL,NOP58,POLR2A,DDX50,HNRNPH3,ORC5,ATM,ADK,IPO4,DDIT3,KAT6A,FEM1C,UBN1,NF1,ATRX,KMT2E,FANCD2,RCHY1,SIRT2,SNAPC4,CUTC,SMARCB1,ANAPC1,KANSL1,YLPM1,JAZF1,ANAPC11,SLC39A7,ANAPC10,ZEB1,RELB,POLR3B,HCFC2,OGG1,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,DEAF1,SKAP2,SIRT6,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,TAF9B,CHAF1A,UBTF,GEMIN5,PAF1,EPN2,EIF4ENIF1,SUFU,GATA6,HLCS,CC2D1B,PQBP1,CRCP,EME1,COPS6,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,TAF1,ZCCHC8,PAX2,DPF2,MED13L,NAMPT,TOX4,CEP164,ELL,WDR27,ATXN2,BANF1,BUD31,NRIP1,ZCCHC7,POLR1E,CPSF3L,RANBP6,TRA2A,XPO5,JMJD1C,ELP3,WBSCR22,PSMA1,LIG4,ISG15,UBE2E1,POP1,SYCP2L,MYBBP1A,INTS5,FDPS,PFDN2,TBL1X,NR2C2AP,TCF12,SNX27,ASH1L,SMARCA4,PBX1,SBDS,ZC3H13,RRN3,MPHOSPH10,BRE,NVL,CPSF3,UTP4,C6orf89,MAML3,HN1,ACSL5,PARP2,GRHL3,POU2F1,ATXN1,DKC1,UBR4,S100A16,ZC3H12A,ARMC4,KPNA3,IKZF4,HNRNPR,COPS5,ARNTL,FKBP5,HEATR1,NFRKB,DNAJC2,TNIK,CMTM8,H2AFJ,DBF4,PPHLN1,ATF7IP,WDR26,MED18,CTNNBL1,ERI3,FBL,MICAL3,RPS6KB2,TOP1,ARNTL2,KDM6B,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,SCMH1,MEN1,PEAK1,SYMPK,HSPA1B,RERE,GADD45A,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,POLR1C,TATDN1,ARHGAP27,HRH1 |
| 8.616e-41 | -92.25 | organelle | cellular component | GO:0043226 | 12606 | 1856 | 17570 | 2233 |
PTP4A1,ARHGAP26,GGT1,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,HMOX2,ABHD6,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,RNMT,LIMA1,EHMT1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,MCM2,ZNF197,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,RUNX1,TPM1,SLC25A26,ZNF532,BANP,EPM2AIP1,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,RBM20,CNST,UBE3A,DHX37,APLF,WDR60,MED24,TNPO3,GEMIN4,MRPL21,PABPC1,PPA1,ANGPT2,MYB,NOM1,RABEPK,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,SRP14,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,SUGCT,C16orf45,VTI1A,DDR2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,RPGRIP1L,NDUFB3,ESAM,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,LRRC75A-AS1,ZNF480,CCNDBP1,MEF2D,GSTCD,SLC35D1,DSP,VPS53,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CATSPERG,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,ACOT11,ANXA5,PTGS1,ZNF710,ACTR3B,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,UQCC1,CYP24A1,CUL7,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,HNRNPLL,MAP2K3,ECM1,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,DBN1,AEBP2,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,LAMA2,KRTCAP2,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,MAPK8IP3,FAN1,SMAD7,LAMTOR3,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,PNPLA3,SNX29,NIPSNAP1,WARS2,USP49,IFT43,HAUS6,SETD2,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,UPK3B,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,NTSR1,RPS29,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,RADIL,PPP1R9A,ZNF121,URB1,FDX1,ANKRD13A,NRF1,IDI1,NUP133,CCDC40,MYH15,BCAP29,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,RAB7A,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,HSPB8,MED20,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,NIFK,ESCO1,MINK1,KIZ,MCM10,AUH,HM13,RFX1,AGO2,ESRG,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,SMPDL3B,DKK1,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,S100A10,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,XPNPEP1,NRP1,BLMH,BMI1,RFXAP,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,CENPB,DPM3,CRACR2A,SSR4,PRPF39,PDCD5,NDUFS7,MTUS1,TECTA,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAP1GAP2,RAP1B,ARID1A,NELFA,SLC26A11,ZNF850,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,PPID,LPIN2,MRPS27,DTNBP1,RMDN3,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,IFT140,SLC4A7,TRAF3,TBXA2R,XRCC4,SETD6,MID1,VWA8,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,SFR1,ABL1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,LYRM4,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DEAF1,TNK2,SESN2,ZNF195,SKAP2,SIRT6,TFPI,ARRDC3,MINA,TMEM216,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,MPC1,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,ZCCHC8,VTA1,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,ZNF354A,WDR27,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,ZNF629,ZNF234,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,SYT1,HERPUD1,UBE2E1,MGAT2,POP1,APBB3,SYCP2L,BICD1,FSCN1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,AGO3,N4BP2L2,NR2C2AP,DMXL2,TCF12,SNX27,CHMP2A,PSTPIP2,CEMIP,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,CBR4,SNTG2,FHIT,ADCK4,VCL,TMEM120B,UTP4,GNG5,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,WDR73,FKBP5,NFRKB,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,IGF2BP2,WDR26,SOGA1,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,DCTN4,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,GPHN,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,ZNF324B,SCMH1,PDE2A,PEAK1,TMEM187,EIF5B,ZNF221,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,GNB3,ASCC1,WDR74,CSPP1,HLTF,CHAC1,NT5C3A,COA1,NUP160,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RABGAP1L,RASSF3,FAAH2,PDS5B,WIZ,FNIP2,ZNF148,HRG,LYRM5,FXN,CDK6,WLS,GNL3,RFX2,MSRB3,AKAP12,MCL1,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,LPP,MEF2C,TNNC1,HERC2,EP400,TRIP6,SLK,KHDRBS1,SIRT7,PRAF2,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,AGL,COQ3,TOMM34,SERBP1,EMC10,HMGCR,FADS1,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,CPT1A,MBNL2,ONECUT2,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,GPN1,ADGRE5,SENP3,CNOT6,WDR33,COG5,SPRED2,FAM208B,DNM3,ABCA3,MAP2K5,ZNF516,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,TMEM150C,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,NT5C,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ARHGEF10,ATP6V0A1,TTC28,FKBP3,FGFR1,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,NOL4L,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,GATC,TMSB10,ARHGAP1,SOX6,HNRNPM,LYPLA2,DIS3L2,ULBP1,NUDC,FGF9,CEP83,CLYBL,POLK,CEP295,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,ZNF467,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,ETFDH,RARS,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLC25A19,PTPN4,GPAM,PSAP,IGBP1,NUDT22,ANAPC4,CORO2B,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,MFGE8,NREP,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,BIRC2,GIT2,ABL2,DHX33,MARVELD2,TRMU,XRCC2,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,TMPO,PTPRK,SF3A1,CDC37,FLNC,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,HARS,ZNF414,BAZ2A,KATNAL1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,FAM206A,EEFSEC,CCDC146,TNFRSF1A,RAD51B,DLX2,C2CD5,CHMP4C,XYLB,SARS,TTN,AOC3,OXNAD1,MCM6,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,RLF,DNAH1,RNF40,ABCA5,SAMD11,PPIL2,GTF2H1,TIMELESS,ALDH18A1,GMDS,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,PPP1R12B,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,PELP1,RPAIN,KDM1A,METTL16,CAD,ZBTB21,TMEM94,DNAJB6,FSIP2,IKBKB,ZDHHC6,HIRIP3,RNF2,ETF1,ZFP37,HIBCH,CORO1A,PRMT3,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,TUBA1A,DDX41,NARS,GLTSCR2,THSD4,CPOX,AKAP13,ENC1,NUP214,PUM3,TMEM186,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,TIMM17A,ZNF333,ZNF436,PUS1,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,PKIB,UNC13D,MIF4GD,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,PRICKLE2,HIST2H3D,GREB1,DDX31,FBXO31,CD44,PCK2,HSD17B12,FAM71E1,GINS3,ZNF654,ZMYM5,TPM4,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,NEU1,ARMC3,ZRANB3,MKX,POLR3G,CENPP,TMEM237,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,POLB,CGN,PRDX6,PRKAB2,DDX19A,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,RPS16,PAK1IP1,RNF111,VPS52,ME1,CEP135,MEIS3,PRADC1,TRMT10A,FUT11,SEH1L,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,TCEB3,CUX1,DESI1,HSH2D,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,ZNF81,VPS13D,DNAH2,SEMA3C,CCNB1IP1,TXN2,SYNPO,PTPN14,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,AK6,OPHN1,GTF2IRD1,PID1,CCDC47,CHD5,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,ENTPD5,COPS3,ATIC,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIGMAR1,POLA1,KIAA0586,PTPN12,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,DAGLA,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,CCDC58,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,RFC4,MPP6,CFAP221,RFC3,PDK1,MTIF2,SFXN4,WDPCP,DLG4,MED16,PNN,POLG2,STK10,DHX57,CPED1,VDR,TAMM41,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,CEP126,LIAS,MON2,IKBKAP,NOL3,GDPD5,REEP5,FOXO3,MAD2L2,TMCO6,NEDD4,ZNF239,ZNF483,RGS17,COMMD9,PTRF,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,LARP4B,NT5M,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,PTK2,APTX,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,KLHL22,ZDHHC11,COL26A1,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,STK4,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,CERS5,FANCD2,RCHY1,PLOD1,ZNF107,BCOR,SIRT2,SNAPC4,CUTC,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ANAPC1,RAP1A,YLPM1,ZNHIT6,ANAPC10,RELB,HYAL1,IPP,POLR3B,PCOLCE2,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,LAMA4,ZBTB17,TRIM13,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,SERGEF,CHAF1A,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,BBIP1,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,TNRC6A,LDAH,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,GLTP,NRIP1,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,C19orf70,DNAH14,ISG15,MYBBP1A,ATAD5,INTS5,SDCCAG8,RRAGA,HK2,PTRH2,ZFP90,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,MMRN2,SLC5A5,MYO7A,FAM210A,SLC9B2,CSTA,PUDP,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,BRE,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,WARS,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,ECHDC1,TNIK,SULT1C2,C17orf80,OXLD1,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,MFSD10,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,DSG2,KDELC1,SHMT2,TTC17,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,ANKMY2,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,PREPL,ZAK,MMP16,ARHGAP27,HRH1 |
| 5.723e-40 | -90.36 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 10597 | 1626 | 17570 | 2233 |
PTP4A1,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,SBF2,CCNL2,ZNF44,HMOX2,ABHD6,CIAPIN1,SKI,ZNF37A,PDZD2,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,RNMT,EHMT1,AP4B1,NFIA,WDHD1,C5AR1,SHISA5,MCM2,ZNF197,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,RUNX1,SLC25A26,ZNF532,BANP,EPM2AIP1,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,RBM20,CNST,UBE3A,DHX37,APLF,MED24,TNPO3,GEMIN4,MRPL21,PABPC1,ANGPT2,MYB,NOM1,RABEPK,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,TSR1,KPNA1,EHMT2,TRAP1,CCDC85B,KIAA0196,SRP14,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,SUGCT,VTI1A,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,LRRC75A-AS1,ZNF480,CCNDBP1,MEF2D,SLC35D1,DSP,VPS53,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,GAS6,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,SNW1,POLR3D,TAF3,NOP16,ANXA5,PTGS1,ZNF710,PNMA1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,UBC,ANXA1,MRPL36,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,UQCC1,CYP24A1,CUL7,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,HNRNPLL,MAP2K3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,AEBP2,ATF4,MIOS,PPARG,CDK4,HSPA5,TSN,PSMG1,SUMO3,KRTCAP2,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,NKD2,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,PNPLA3,NIPSNAP1,WARS2,USP49,HAUS6,SETD2,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,SNX24,SIL1,DTD1,PTP4A2,BCCIP,USP7,SART1,ID1,OLFM2,SUCLG1,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,URB1,ZNF121,FDX1,ANKRD13A,NRF1,IDI1,NUP133,BCAP29,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,RAB7A,VIM,CA5B,ZNF251,TJAP1,EXO1,KLF4,INTS9,HSPB8,MED20,FAHD1,MUTYH,ZNF507,DMGDH,NIFK,ESCO1,MINK1,MCM10,HM13,AUH,RFX1,AGO2,ESRG,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,YIPF3,EXOG,PALLD,POLR3A,DKK1,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,NRP1,BLMH,BMI1,RFXAP,ZMAT3,NMD3,PRPF38B,C9orf78,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,CENPB,DPM3,CRACR2A,SSR4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAP1GAP2,ARID1A,NELFA,SLC26A11,ZNF850,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,HNRNPA3,RING1,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,PPID,LPIN2,MRPS27,DTNBP1,TTC3,RMDN3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,TRAF3,TBXA2R,SETD6,XRCC4,VWA8,NOSTRIN,BRAF,B4GALT5,FARS2,RCAN1,OPA1,RPS6KA5,SFR1,ABL1,ELP5,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,LYRM4,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,ZNF195,SKAP2,SIRT6,TFPI,ARRDC3,MINA,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,MPC1,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,DCAF5,MTCH1,ZCCHC8,VTA1,UBXN1,PCSK7,SMG7,TIMM10,NAMPT,ELL,P3H1,ZNF354A,WDR27,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,ZNF629,ZNF234,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,SYT1,HERPUD1,UBE2E1,MGAT2,POP1,APBB3,SYCP2L,BICD1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,CEMIP,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,CBR4,FHIT,ADCK4,TMEM120B,UTP4,C6orf89,AUP1,MAML3,NARS2,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,FKBP5,NFRKB,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,CMTM8,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,IGF2BP2,WDR26,PIP4K2A,GFM2,PEX7,SEC24C,DCTN4,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,FGF2,ZNF821,KDM5A,PSPC1,SCMH1,ZNF324B,PDE2A,PEAK1,EIF5B,TMEM187,ZNF221,SERINC1,DAGLB,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,ASCC1,WDR74,HLTF,CHAC1,NT5C3A,COA1,NUP160,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RABGAP1L,PDS5B,WIZ,FNIP2,ZNF148,HRG,LYRM5,FXN,CDK6,WLS,GNL3,RFX2,MSRB3,MCL1,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,LPP,MEF2C,TNNC1,HERC2,EP400,TRIP6,KHDRBS1,SIRT7,PRAF2,PLA2G12A,RSF1,CLINT1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,COQ3,AGL,TOMM34,SERBP1,EMC10,HMGCR,FADS1,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,NCDN,ZNF783,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,GPN1,SENP3,CNOT6,WDR33,COG5,SPRED2,FAM208B,DNM3,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,NPAS2,ATP6V1A,PDK4,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,TMEM150C,PRKD3,BCAS2,ABCA12,ZKSCAN1,ERI1,FMNL1,ATRIP,NT5C,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ATP6V0A1,FKBP3,FGFR1,PES1,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,NOL4L,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,GATC,SOX6,HNRNPM,DIS3L2,ULBP1,NUDC,CEP83,CLYBL,POLK,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,ZNF467,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,RARS,ETFDH,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLC25A19,PSAP,GPAM,NUDT22,ANAPC4,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,NREP,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,GIT2,BIRC2,DHX33,TRMU,XRCC2,UBAP2L,ZNF85,POLE3,RAN,ETV1,MPST,SF3A1,TMPO,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,ZNF414,BAZ2A,HARS,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,KIF16B,PEX1,GLS,MSRA,ZNF622,TP53BP1,PER1,EEFSEC,FAM206A,TNFRSF1A,RAD51B,DLX2,C2CD5,CHMP4C,AOC3,OXNAD1,TTN,SARS,MCM6,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,RLF,RNF40,ABCA5,SAMD11,PPIL2,GTF2H1,TIMELESS,ALDH18A1,NAA38,TRAPPC9,CAMKK2,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,TBPL1,ZNF430,PPP1R12B,HMBS,BRSK2,NAPA,TESC,RNF114,NDUFA5,LPCAT2,RBFOX2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,METTL16,CAD,ZBTB21,TMEM94,DNAJB6,FSIP2,ZDHHC6,IKBKB,HIRIP3,RNF2,ETF1,ZFP37,HIBCH,CORO1A,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,TUBA1A,DDX41,NARS,GLTSCR2,CPOX,AKAP13,ENC1,NUP214,USP36,TMEM186,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,RBBP8,SIX5,TIMM17A,ZNF333,CLEC16A,ZNF436,PUS1,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,PKIB,UNC13D,MIF4GD,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,HIST2H3D,PRICKLE2,DDX31,CD44,PCK2,HSD17B12,FAM71E1,GINS3,ZNF654,ZMYM5,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,CHCHD6,TMEM175,NEU1,ZRANB3,POLR3G,CENPP,MKX,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,MIPOL1,GCSH,POLB,MYCBP2,PRDX6,PRKAB2,DDX19A,PLRG1,TMEM109,IKBIP,AARS,UBR5,MGA,PAK1IP1,RNF111,VPS52,ME1,MEIS3,TRMT10A,FUT11,SEH1L,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,DESI1,HSH2D,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,ZNF81,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,EGR1,CELSR1,ZHX3,ANKRD17,CCDC53,AK6,GTF2IRD1,PID1,CCDC47,CHD5,ANXA10,IGF2BP3,PRKCE,FKBP1A,PI4KB,ENTPD5,ZNF586,COPS3,ATIC,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIGMAR1,POLA1,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,D2HGDH,ZBTB12,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,PTCD2,AMOTL1,CCDC58,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,PHC2,TERF2IP,FLAD1,CHD7,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,RFC4,RFC3,PDK1,MTIF2,SFXN4,DLG4,MED16,PNN,POLG2,DHX57,CPED1,VDR,TAMM41,YIPF2,DNAJA3,ZNF236,H2AFX,ALKBH1,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,LIAS,MON2,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,TMCO6,NEDD4,ZNF239,ZNF483,RGS17,COMMD9,PTRF,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,COPS7B,UPF2,NLGN3,EXOSC4,YBX3,LARP4B,NT5M,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,APTX,PTK2,OASL,NOP58,MMAA,POLR2A,ECH1,YIF1A,COL26A1,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,STK4,PHF3,MVK,FEM1C,UBN1,NF1,CERS5,FANCD2,RCHY1,ZNF107,PLOD1,BCOR,SIRT2,SNAPC4,CUTC,AHCYL2,SMARCB1,MRPS30,SRPRB,RTN1,ANAPC1,RAP1A,YLPM1,ANAPC10,RELB,HYAL1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,CMIP,HDAC8,CAV1,ZSCAN2,SOX4,SERGEF,CHAF1A,TAF9B,GEMIN5,RHOU,UBTF,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,MKL2,PQBP1,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,TNRC6A,LDAH,PIGN,CHST11,AK2,FN1,TAF1,SEC24D,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,C11orf54,XPO7,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,NRIP1,POLR1E,CPSF3L,VOPP1,RANBP6,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,C19orf70,ISG15,MYBBP1A,ATAD5,INTS5,HK2,RRAGA,PTRH2,ZFP90,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,SLC5A5,MYO7A,FAM210A,SLC9B2,CSTA,GBF1,SLC39A1,MIEF1,ZSCAN5A,VPS18,BRE,CAMTA2,RPS6KL1,ZNF142,CPSF3,ZNF460,TMEM14C,HTRA2,HN1,TMLHE,MOSPD1,MCEE,ACSL5,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAB10,WARS,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,TNIK,OXLD1,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,MFSD10,HDDC2,MAN1A1,MRPS11,CTNNBL1,KDELC1,SHMT2,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,HSPA1B,RERE,MFN2,ZNF708,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,PREPL,TATDN1,ZAK,MMP16,ARHGAP27,HRH1 |
| 5.113e-39 | -88.17 | membrane-enclosed lumen | cellular component | GO:0031974 | 4223 | 792 | 17570 | 2233 |
ASCC1,THOC5,WDR74,MRPL10,NAT10,HLTF,CCNL2,CIAPIN1,SKI,NEK6,FAM222B,SREBF2,ZFHX3,IKZF5,NSRP1,PDS5B,ZNF148,FNIP2,KDM5C,HRG,SRRM2,ZNRD1,FXN,FTSJ3,CDK6,PPM1K,HMBOX1,RNMT,GNL3,EHMT1,AP4B1,NFIA,WDHD1,MCL1,MCM2,RBM28,TMSB4X,STOML2,PYCR1,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,FIP1L1,RBP1,MEF2C,BANP,HERC2,TNNC1,EP400,KHDRBS1,SIRT7,RSF1,PDCD7,CLINT1,PARN,CDC73,YARS2,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,ANP32B,GEMIN4,NOC3L,MRPL21,PRMT5,COQ3,TOMM34,MYB,NOM1,GATAD2B,GTF2H3,TIMM8B,COL17A1,WDR61,STAG1,MYO10,ARID5B,IDH3G,USP10,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,TSR1,KPNA1,GTF2A1,EHMT2,TRAP1,CDK9,GPN1,SENP3,WDR33,COG5,FAM208B,DDX18,NPAS2,PDK4,ISG20L2,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ACD,ERI1,WAC,MMP14,ATRIP,INTS12,MSH4,MGLL,MTHFD2L,ZC3H3,LSM10,KMT2D,GARS,STAMBP,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,CCNDBP1,PES1,TAF2,CDC16,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,MAPT,HMGA2,NOL4L,SHQ1,XPC,SF3A3,ID2,JMJD6,GAS6,AKT1S1,TRIM22,IP6K2,BHLHE40,TGFB2,ZNF691,RSRC1,PSMF1,MBNL1,KRI1,TADA3,SNW1,POLR3D,SUV39H2,TAF3,NOP16,PNMA1,SOX6,HNRNPM,DIS3L2,NUDC,VPS37A,DDX24,POLK,ZC3H18,CCDC113,FOXC1,UBC,MRPL36,ANXA1,RPA1,TRIB3,TOE1,ETFDH,NSD1,RARS,POLE2,ARID3B,ACOX1,AEN,PSAP,NUDT22,ANAPC4,KDM4C,CYP24A1,CUL7,TRIM16,PPARGC1B,TFIP11,WDR13,POLR1A,CSNK2A1,NLE1,GIT2,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,ANKRD11,UBAP2L,RAN,POLE3,ZMYM2,SF3A1,METTL1,CHD9,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,HSPA5,MED27,COL4A3BP,NOL6,PSMG1,SUMO3,BRCA1,DLST,LSG1,CXADR,MLLT10,GLS,MSRA,ZNF622,TCF7L1,TP53BP1,CHD3,FAM206A,ARL4A,E2F4,RAD51B,PRPF4,TSEN2,MAGI1,UQCC2,TTN,MCM6,FOXO1,HSD17B10,SMAD7,FAN1,ARID1B,RNF40,SUB1,MBD2,VPS72,PPIL2,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,TLE3,HOMER2,HAUS6,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PWP1,PRPF40B,ATXN7,PALB2,SYNCRIP,SNAP23,TBPL1,SIL1,PPP1R12B,USP7,SART1,ID1,SUCLG1,ARID2,RBFOX2,PPP2R2A,RSL1D1,TNKS1BP1,PELP1,RPAIN,URB1,FDX1,KDM1A,CAD,NRF1,TMEM94,DNAJB6,HIRIP3,HIBCH,RNF2,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,AKAP8L,GLTSCR2,CPOX,CA5B,ENC1,NUP214,PUM3,USP36,ATP5D,EXO1,SMAD3,RBBP8,SIX5,TIMM17A,KLF4,ZNF436,INTS9,HSPB8,PUS1,MED20,FAHD1,MUTYH,DMGDH,NIFK,ESCO1,MCM10,MIF4GD,AUH,RFX1,AGO2,MAP1S,APRT,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,PTPN2,FAM50A,SURF2,ZNF561,HIST2H3D,DDX31,POLR1B,PCK2,SNAPC5,PCSK6,TRNP1,GINS3,AP4S1,SMARCAD1,TOP3A,FERMT2,C11orf49,YIPF3,HIST1H4J,PIK3CB,NEU1,POLR3A,ZRANB3,CENPP,POLR3G,NOL10,GPC2,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,RBPJ,TAF12,XPO6,GCSH,POLB,CUL4A,PRKCSH,PRKAB2,PLRG1,GYG1,PRKCA,UBR5,LPIN1,MGA,SUCLG2,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,ACADS,SNU13,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,SUPT20H,HIST1H2BL,SON,MAK16,SAP30BP,CLNS1A,SPOP,OSBPL1A,GZF1,DOT1L,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,CFD,CCNB1IP1,TXN2,BMI1,ZMAT3,NMD3,PTPN14,WDR75,C9orf78,DROSHA,EGR1,CELSR1,PRPF31,LARS2,ZHX3,AK6,GTF2IRD1,PID1,CRACR2A,CHD5,NDUFS7,HR,ZNF586,USPL1,COPS3,MYC,GTF3C3,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,PCCA,POLA1,ARID1A,NELFA,PLCB1,SLC26A11,LYRM7,PHF6,CAT,ASCC3,ALKBH3,HIF1A,PMEPA1,VCAN,SPEN,SRP68,MED15,D2HGDH,PURB,NCOR1,CNDP2,SMYD3,LIN28B,URB2,UROD,NDUFB5,OLA1,SPATS2L,POP5,FOSL2,HNRNPA3,RING1,TRIM66,NOP56,TERF2IP,PHC2,FLAD1,CHD7,DECR1,SLX4,SHC1,KDM2A,PPID,UCHL5,GLYR1,TTC3,SSBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,PDK1,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,ZBTB25,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,H2AFX,MDN1,PDCD11,NOLC1,XRCC4,NCOR2,UTP14A,C10orf2,TCF3,MRI1,NFX1,FARS2,MLH1,OPA1,NOL3,IKBKAP,RPS6KA5,FOXO3,MAD2L2,SFR1,ABL1,PTRF,TRIAP1,PMPCA,PHYKPL,HARS2,COPS7B,CELF1,EXOSC4,S100A14,LARP4B,NT5M,CLK2,PXN,APEX1,WDFY3,WDR18,BMS1,APTX,OASL,NOP58,MMAA,POLR2A,DDX50,COL26A1,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,IPO4,KAT6A,LYRM4,FEM1C,UBN1,ATRX,NF1,KMT2E,RARS2,FANCD2,RCHY1,SIRT2,SNAPC4,CUTC,SMARCB1,ANAPC1,KANSL1,YLPM1,JAZF1,SLC39A7,ANAPC11,ANAPC10,RELB,ZEB1,HYAL1,POLR3B,HCFC2,OGG1,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,DEAF1,SKAP2,SIRT6,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,CHAF1A,TIMM44,TAF9B,GEMIN5,UBTF,PAF1,EPN2,EIF4ENIF1,SUFU,GATA6,HLCS,TRMT5,CC2D1B,PQBP1,CRCP,CLU,EME1,ZC3H8,COPS6,NOCT,DMTF1,EMSY,TNRC6A,AK2,FN1,ZCCHC8,TAF1,PAX2,DPF2,MED13L,TIMM10,ETFB,NAMPT,TOX4,CEP164,ELL,P3H1,WDR27,ATXN2,BANF1,BUD31,NRIP1,PRF1,ZCCHC7,POLR1E,CPSF3L,RANBP6,TRA2A,XPO5,JMJD1C,ELP3,WBSCR22,LIG4,PSMA1,ISG15,UBE2E1,POP1,SYCP2L,MYBBP1A,INTS5,FDPS,PFDN2,TBL1X,PDSS2,NR2C2AP,TCF12,SNX27,ASH1L,SMARCA4,PBX1,ARSJ,GBF1,SBDS,ZC3H13,RRN3,MPHOSPH10,BRE,NVL,CBR4,CPSF3,UTP4,C6orf89,HTRA2,MAML3,TMLHE,HN1,MCEE,NARS2,ACSL5,COL5A2,PARP2,GRHL3,MRRF,NLN,POU2F1,ATXN1,DKC1,EDEM2,UBR4,S100A16,ARMC4,ZC3H12A,IKZF4,KPNA3,HNRNPR,COPS5,ARNTL,FKBP5,HEATR1,NFRKB,DNAJC2,BCKDK,TNIK,CMTM8,H2AFJ,DBF4,PPHLN1,MED18,WDR26,ATF7IP,CHCHD10,GFM2,MRPS11,PEX7,CTNNBL1,KDELC1,SHMT2,ERI3,FBL,MICAL3,TOP1,RPS6KB2,KDM6B,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,SCMH1,PDE2A,MEN1,PEAK1,SYMPK,HSPA1B,RERE,GADD45A,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,POLR1C,TATDN1,MMP16,ARHGAP27,HRH1 |
| 6.994e-39 | -87.86 | intracellular organelle lumen | cellular component | GO:0070013 | 4116 | 776 | 17570 | 2233 |
ASCC1,THOC5,WDR74,MRPL10,NAT10,HLTF,CCNL2,CIAPIN1,SKI,NEK6,FAM222B,SREBF2,ZFHX3,IKZF5,NSRP1,PDS5B,ZNF148,FNIP2,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,CDK6,PPM1K,HMBOX1,RNMT,GNL3,EHMT1,AP4B1,NFIA,WDHD1,MCL1,MCM2,RBM28,PYCR1,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,FIP1L1,RBP1,MEF2C,BANP,HERC2,TNNC1,EP400,KHDRBS1,SIRT7,RSF1,PDCD7,CLINT1,PARN,CDC73,YARS2,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,ANP32B,GEMIN4,NOC3L,MRPL21,PRMT5,COQ3,TOMM34,MYB,NOM1,GATAD2B,GTF2H3,COL17A1,WDR61,STAG1,MYO10,ARID5B,IDH3G,USP10,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,TSR1,KPNA1,GTF2A1,EHMT2,TRAP1,CDK9,GPN1,SENP3,WDR33,COG5,FAM208B,DDX18,NPAS2,PDK4,ISG20L2,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ACD,ERI1,WAC,MMP14,ATRIP,INTS12,MSH4,MGLL,MTHFD2L,ZC3H3,LSM10,KMT2D,GARS,STAMBP,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,CCNDBP1,PES1,TAF2,CDC16,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,MAPT,HMGA2,NOL4L,SHQ1,XPC,SF3A3,ID2,JMJD6,GAS6,AKT1S1,TRIM22,IP6K2,BHLHE40,ZNF691,RSRC1,PSMF1,MBNL1,KRI1,TADA3,SNW1,POLR3D,SUV39H2,TAF3,NOP16,PNMA1,SOX6,HNRNPM,DIS3L2,NUDC,VPS37A,DDX24,POLK,ZC3H18,CCDC113,FOXC1,UBC,MRPL36,ANXA1,RPA1,TRIB3,TOE1,ETFDH,NSD1,RARS,POLE2,ARID3B,ACOX1,AEN,PSAP,NUDT22,ANAPC4,KDM4C,CYP24A1,CUL7,TRIM16,PPARGC1B,TFIP11,WDR13,POLR1A,CSNK2A1,NLE1,GIT2,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,ANKRD11,UBAP2L,RAN,POLE3,ZMYM2,SF3A1,METTL1,CHD9,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,HSPA5,MED27,COL4A3BP,NOL6,PSMG1,SUMO3,BRCA1,DLST,LSG1,CXADR,MLLT10,GLS,MSRA,ZNF622,TCF7L1,TP53BP1,CHD3,FAM206A,ARL4A,E2F4,RAD51B,PRPF4,TSEN2,MAGI1,UQCC2,TTN,MCM6,FOXO1,HSD17B10,SMAD7,FAN1,ARID1B,RNF40,SUB1,MBD2,VPS72,PPIL2,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,TLE3,HOMER2,HAUS6,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PWP1,PRPF40B,ATXN7,PALB2,SYNCRIP,SNAP23,TBPL1,SIL1,PPP1R12B,USP7,SART1,ID1,SUCLG1,ARID2,RBFOX2,PPP2R2A,RSL1D1,TNKS1BP1,PELP1,RPAIN,URB1,FDX1,KDM1A,CAD,NRF1,TMEM94,DNAJB6,HIRIP3,HIBCH,RNF2,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,AKAP8L,GLTSCR2,CA5B,ENC1,NUP214,PUM3,USP36,ATP5D,EXO1,SMAD3,RBBP8,SIX5,TIMM17A,KLF4,ZNF436,INTS9,HSPB8,PUS1,MED20,FAHD1,MUTYH,DMGDH,NIFK,ESCO1,MCM10,MIF4GD,AUH,RFX1,AGO2,MAP1S,APRT,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,PTPN2,FAM50A,SURF2,ZNF561,HIST2H3D,DDX31,POLR1B,PCK2,SNAPC5,PCSK6,TRNP1,GINS3,AP4S1,SMARCAD1,TOP3A,FERMT2,C11orf49,YIPF3,HIST1H4J,PIK3CB,NEU1,POLR3A,ZRANB3,CENPP,POLR3G,NOL10,GPC2,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,RBPJ,TAF12,XPO6,GCSH,POLB,CUL4A,PRKCSH,PRKAB2,PLRG1,GYG1,PRKCA,UBR5,LPIN1,MGA,SUCLG2,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,ACADS,SNU13,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,SUPT20H,HIST1H2BL,SON,MAK16,SAP30BP,CLNS1A,SPOP,OSBPL1A,GZF1,DOT1L,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,CCNB1IP1,TXN2,BMI1,ZMAT3,NMD3,PTPN14,WDR75,C9orf78,DROSHA,EGR1,CELSR1,PRPF31,LARS2,ZHX3,AK6,GTF2IRD1,PID1,CRACR2A,CHD5,NDUFS7,HR,ZNF586,USPL1,COPS3,MYC,GTF3C3,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,PCCA,POLA1,ARID1A,NELFA,PLCB1,SLC26A11,LYRM7,PHF6,CAT,ASCC3,ALKBH3,HIF1A,PMEPA1,VCAN,SPEN,SRP68,MED15,D2HGDH,PURB,NCOR1,CNDP2,SMYD3,LIN28B,URB2,UROD,NDUFB5,OLA1,SPATS2L,POP5,FOSL2,HNRNPA3,RING1,TRIM66,NOP56,TERF2IP,PHC2,FLAD1,CHD7,DECR1,SLX4,SHC1,KDM2A,PPID,UCHL5,GLYR1,TTC3,SSBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,PDK1,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,ZBTB25,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,H2AFX,MDN1,PDCD11,NOLC1,XRCC4,NCOR2,UTP14A,C10orf2,TCF3,MRI1,NFX1,FARS2,MLH1,OPA1,NOL3,IKBKAP,RPS6KA5,FOXO3,MAD2L2,SFR1,ABL1,PTRF,PMPCA,PHYKPL,HARS2,COPS7B,CELF1,EXOSC4,S100A14,LARP4B,NT5M,CLK2,PXN,APEX1,WDFY3,WDR18,BMS1,APTX,OASL,NOP58,MMAA,POLR2A,DDX50,COL26A1,HNRNPH3,ORC5,ATM,ADK,DDIT3,IPO4,KAT6A,LYRM4,FEM1C,UBN1,ATRX,NF1,KMT2E,RARS2,FANCD2,RCHY1,SIRT2,SNAPC4,CUTC,SMARCB1,ANAPC1,KANSL1,YLPM1,JAZF1,SLC39A7,ANAPC11,ANAPC10,RELB,ZEB1,HYAL1,POLR3B,HCFC2,OGG1,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,DEAF1,SKAP2,SIRT6,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,CHAF1A,TIMM44,TAF9B,GEMIN5,UBTF,PAF1,EPN2,EIF4ENIF1,SUFU,GATA6,HLCS,TRMT5,CC2D1B,PQBP1,CRCP,EME1,ZC3H8,COPS6,NOCT,DMTF1,EMSY,TNRC6A,ZCCHC8,TAF1,PAX2,DPF2,MED13L,ETFB,NAMPT,TOX4,CEP164,ELL,P3H1,WDR27,ATXN2,BANF1,BUD31,NRIP1,PRF1,ZCCHC7,POLR1E,CPSF3L,RANBP6,TRA2A,XPO5,JMJD1C,ELP3,WBSCR22,LIG4,PSMA1,ISG15,UBE2E1,POP1,SYCP2L,MYBBP1A,INTS5,FDPS,PFDN2,TBL1X,PDSS2,NR2C2AP,TCF12,SNX27,ASH1L,SMARCA4,PBX1,ARSJ,GBF1,SBDS,ZC3H13,RRN3,MPHOSPH10,BRE,NVL,CBR4,CPSF3,UTP4,C6orf89,MAML3,TMLHE,HN1,MCEE,NARS2,ACSL5,COL5A2,PARP2,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,UBR4,S100A16,ARMC4,ZC3H12A,IKZF4,KPNA3,HNRNPR,COPS5,ARNTL,FKBP5,HEATR1,NFRKB,DNAJC2,BCKDK,TNIK,CMTM8,H2AFJ,DBF4,PPHLN1,MED18,WDR26,ATF7IP,GFM2,MRPS11,PEX7,CTNNBL1,KDELC1,SHMT2,ERI3,FBL,MICAL3,TOP1,RPS6KB2,KDM6B,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,SCMH1,PDE2A,MEN1,PEAK1,SYMPK,HSPA1B,RERE,GADD45A,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,POLR1C,TATDN1,MMP16,ARHGAP27,HRH1 |
| 2.095e-38 | -86.76 | organelle lumen | cellular component | GO:0043233 | 4169 | 782 | 17570 | 2233 |
ASCC1,THOC5,WDR74,MRPL10,NAT10,HLTF,CCNL2,CIAPIN1,SKI,NEK6,FAM222B,SREBF2,ZFHX3,IKZF5,NSRP1,PDS5B,ZNF148,FNIP2,KDM5C,HRG,SRRM2,ZNRD1,FXN,FTSJ3,CDK6,PPM1K,HMBOX1,RNMT,GNL3,EHMT1,AP4B1,NFIA,WDHD1,MCL1,MCM2,RBM28,TMSB4X,PYCR1,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,FIP1L1,RBP1,MEF2C,BANP,HERC2,TNNC1,EP400,KHDRBS1,SIRT7,RSF1,PDCD7,CLINT1,PARN,CDC73,YARS2,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,ANP32B,GEMIN4,NOC3L,MRPL21,PRMT5,COQ3,TOMM34,MYB,NOM1,GATAD2B,GTF2H3,COL17A1,WDR61,STAG1,MYO10,ARID5B,IDH3G,USP10,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,TSR1,KPNA1,GTF2A1,EHMT2,TRAP1,CDK9,GPN1,SENP3,WDR33,COG5,FAM208B,DDX18,NPAS2,PDK4,ISG20L2,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ACD,ERI1,WAC,MMP14,ATRIP,INTS12,MSH4,MGLL,MTHFD2L,ZC3H3,LSM10,KMT2D,GARS,STAMBP,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,CCNDBP1,PES1,TAF2,CDC16,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,MAPT,HMGA2,NOL4L,SHQ1,XPC,SF3A3,ID2,JMJD6,GAS6,AKT1S1,TRIM22,IP6K2,BHLHE40,TGFB2,ZNF691,RSRC1,PSMF1,MBNL1,KRI1,TADA3,SNW1,POLR3D,SUV39H2,TAF3,NOP16,PNMA1,SOX6,HNRNPM,DIS3L2,NUDC,VPS37A,DDX24,POLK,ZC3H18,CCDC113,FOXC1,UBC,ANXA1,MRPL36,RPA1,TRIB3,TOE1,ETFDH,NSD1,RARS,POLE2,ARID3B,ACOX1,AEN,PSAP,NUDT22,ANAPC4,KDM4C,CYP24A1,CUL7,TRIM16,PPARGC1B,TFIP11,WDR13,POLR1A,CSNK2A1,NLE1,GIT2,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,ANKRD11,UBAP2L,RAN,POLE3,ZMYM2,SF3A1,METTL1,CHD9,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,HSPA5,MED27,COL4A3BP,NOL6,PSMG1,SUMO3,BRCA1,DLST,LSG1,CXADR,MLLT10,GLS,MSRA,ZNF622,TCF7L1,TP53BP1,CHD3,FAM206A,ARL4A,E2F4,RAD51B,PRPF4,TSEN2,MAGI1,UQCC2,TTN,MCM6,FOXO1,HSD17B10,SMAD7,FAN1,ARID1B,RNF40,SUB1,MBD2,VPS72,PPIL2,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,TLE3,HOMER2,HAUS6,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,SNAP23,TBPL1,SIL1,PPP1R12B,USP7,SART1,ID1,SUCLG1,ARID2,RBFOX2,PPP2R2A,RSL1D1,TNKS1BP1,PELP1,RPAIN,URB1,FDX1,KDM1A,CAD,NRF1,TMEM94,DNAJB6,HIRIP3,HIBCH,RNF2,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,AKAP8L,GLTSCR2,CA5B,ENC1,NUP214,PUM3,USP36,ATP5D,EXO1,SMAD3,RBBP8,SIX5,TIMM17A,KLF4,ZNF436,INTS9,HSPB8,PUS1,MED20,FAHD1,MUTYH,DMGDH,NIFK,ESCO1,MCM10,MIF4GD,AUH,RFX1,AGO2,MAP1S,APRT,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,PTPN2,FAM50A,SURF2,ZNF561,HIST2H3D,DDX31,POLR1B,PCK2,SNAPC5,PCSK6,TRNP1,GINS3,AP4S1,SMARCAD1,TOP3A,FERMT2,C11orf49,YIPF3,HIST1H4J,PIK3CB,NEU1,POLR3A,ZRANB3,CENPP,POLR3G,NOL10,GPC2,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,RBPJ,TAF12,XPO6,GCSH,POLB,CUL4A,PRKCSH,PRKAB2,PLRG1,GYG1,PRKCA,UBR5,LPIN1,MGA,SUCLG2,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,ACADS,SNU13,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,SUPT20H,HIST1H2BL,SON,MAK16,SAP30BP,CLNS1A,SPOP,OSBPL1A,GZF1,DOT1L,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,CFD,CCNB1IP1,TXN2,BMI1,ZMAT3,NMD3,PTPN14,WDR75,C9orf78,DROSHA,EGR1,CELSR1,PRPF31,LARS2,ZHX3,AK6,GTF2IRD1,PID1,CRACR2A,CHD5,NDUFS7,HR,ZNF586,USPL1,COPS3,MYC,GTF3C3,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,PCCA,POLA1,ARID1A,NELFA,PLCB1,SLC26A11,LYRM7,PHF6,CAT,ASCC3,ALKBH3,HIF1A,PMEPA1,VCAN,SPEN,SRP68,MED15,D2HGDH,PURB,NCOR1,CNDP2,SMYD3,LIN28B,URB2,UROD,NDUFB5,OLA1,SPATS2L,POP5,FOSL2,HNRNPA3,RING1,TRIM66,NOP56,TERF2IP,PHC2,FLAD1,CHD7,DECR1,SLX4,SHC1,KDM2A,PPID,UCHL5,GLYR1,TTC3,SSBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,PDK1,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,ZBTB25,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,H2AFX,MDN1,PDCD11,NOLC1,XRCC4,NCOR2,UTP14A,C10orf2,MRI1,TCF3,NFX1,FARS2,MLH1,OPA1,NOL3,IKBKAP,RPS6KA5,FOXO3,MAD2L2,SFR1,ABL1,PTRF,PMPCA,PHYKPL,HARS2,COPS7B,CELF1,EXOSC4,S100A14,LARP4B,NT5M,CLK2,PXN,APEX1,WDFY3,WDR18,BMS1,APTX,OASL,NOP58,MMAA,POLR2A,DDX50,COL26A1,HNRNPH3,ORC5,ATM,ADK,DDIT3,IPO4,KAT6A,LYRM4,FEM1C,UBN1,ATRX,NF1,KMT2E,RARS2,FANCD2,RCHY1,SIRT2,SNAPC4,CUTC,SMARCB1,ANAPC1,KANSL1,YLPM1,JAZF1,SLC39A7,ANAPC11,ANAPC10,RELB,ZEB1,HYAL1,POLR3B,HCFC2,OGG1,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,DEAF1,SKAP2,SIRT6,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,CHAF1A,TIMM44,TAF9B,GEMIN5,UBTF,PAF1,EPN2,EIF4ENIF1,SUFU,GATA6,HLCS,TRMT5,CC2D1B,PQBP1,CRCP,CLU,EME1,ZC3H8,COPS6,NOCT,DMTF1,EMSY,TNRC6A,FN1,ZCCHC8,TAF1,PAX2,DPF2,MED13L,ETFB,NAMPT,TOX4,CEP164,ELL,P3H1,WDR27,ATXN2,BANF1,BUD31,NRIP1,PRF1,ZCCHC7,POLR1E,CPSF3L,RANBP6,TRA2A,XPO5,JMJD1C,ELP3,WBSCR22,LIG4,PSMA1,ISG15,UBE2E1,POP1,SYCP2L,MYBBP1A,INTS5,FDPS,PFDN2,TBL1X,PDSS2,NR2C2AP,TCF12,SNX27,ASH1L,SMARCA4,PBX1,ARSJ,GBF1,SBDS,ZC3H13,RRN3,MPHOSPH10,BRE,NVL,CBR4,CPSF3,UTP4,C6orf89,MAML3,TMLHE,HN1,MCEE,NARS2,ACSL5,COL5A2,PARP2,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,UBR4,S100A16,ARMC4,ZC3H12A,IKZF4,KPNA3,HNRNPR,COPS5,ARNTL,FKBP5,HEATR1,NFRKB,DNAJC2,BCKDK,TNIK,CMTM8,H2AFJ,DBF4,PPHLN1,MED18,WDR26,ATF7IP,GFM2,MRPS11,PEX7,CTNNBL1,KDELC1,SHMT2,ERI3,FBL,MICAL3,TOP1,RPS6KB2,KDM6B,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,SCMH1,PDE2A,MEN1,PEAK1,SYMPK,HSPA1B,RERE,GADD45A,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,POLR1C,TATDN1,MMP16,ARHGAP27,HRH1 |
| 8.646e-38 | -85.34 | intracellular organelle part | cellular component | GO:0044446 | 7812 | 1275 | 17570 | 2233 |
PTP4A1,THOC5,ACTG1,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,CIAPIN1,SKI,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,RNMT,LIMA1,EHMT1,AP4B1,NFIA,KIF15,WDHD1,SHISA5,MCM2,PYCR1,AHNAK,RBSN,RAD18,SYNGR2,MPV17,RUNX1,TPM1,SLC25A26,BANP,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,CNST,DHX37,APLF,MED24,TNPO3,GEMIN4,MRPL21,PABPC1,MYB,NOM1,RABEPK,GATAD2B,ALG6,WDR61,STAG1,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,CCDC85B,RAB11FIP4,GTF2H2C,PAFAH1B1,VTI1A,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,RPGRIP1L,NDUFB3,SPG21,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PXK,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,ZNF480,CCNDBP1,MEF2D,SLC35D1,DSP,VPS53,ARHGAP21,KDM4B,ELP2,NSMCE2,POLR3E,HOXA3,RPS6KB1,CEP170,RAB30,MAPT,HMGA2,SHQ1,GAS6,TRIM22,IP6K2,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,PTGS1,ACTR3B,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,ZC3H18,CCDC113,UBC,ANXA1,MRPL36,NSD1,ACOX1,SRD5A3,AEN,UQCC1,CYP24A1,CUL7,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,ZMYM2,SLC25A23,DBN1,AEBP2,ATF4,MIOS,PPARG,CDK4,HSPA5,PSMG1,SUMO3,KRTCAP2,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,LSS,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,PRPF4,TSEN2,MAGI1,UQCC2,FOXO1,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ARID1B,SPIRE1,SUB1,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,PNPLA3,NIPSNAP1,WARS2,IFT43,SETD2,HAUS6,CYB5B,TCF7L2,PRPF40B,SNX24,SIL1,SH3PXD2A,BCCIP,USP7,SART1,ID1,SUCLG1,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,SLC2A1,RPS29,TNKS1BP1,RADIL,PPP1R9A,URB1,FDX1,NRF1,NUP133,MYH15,BCAP29,SPIDR,IPO11,PRPF19,KDM3B,AKAP8L,RAB7A,VIM,CA5B,TJAP1,EXO1,IFT81,KLF4,INTS9,HSPB8,MED20,FAHD1,MUTYH,PARD3,DMGDH,NIFK,ESCO1,KIZ,MCM10,HM13,AUH,RFX1,AGO2,APRT,RBM19,FOXP1,POGZ,HIST2H2AB,SLC25A20,TTC1,SURF2,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,YIPF3,EXOG,PALLD,POLR3A,DKK1,NOL10,TAF4,BCAS3,FNTB,USP20,RBPJ,TAF12,XPO6,KIF1B,CUL4A,PRKCSH,GYG1,PRKCA,LPIN1,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ACADS,GDAP1,EFHC1,CAMSAP2,SUPT20H,HIST1H2BL,SON,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,NSMCE1,ARL6IP5,LUC7L3,CFD,NRP1,BMI1,ZMAT3,NMD3,PRPF38B,C9orf78,JUP,PRPF31,LARS2,ST6GAL1,CENPB,DPM3,CRACR2A,SSR4,PRPF39,NDUFS7,MTUS1,HR,USPL1,MYC,PIGG,CAV2,FDFT1,EXOSC2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAP1GAP2,ARID1A,NELFA,SLC26A11,PHF6,ATP9B,CAT,SEC31A,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,POP5,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,DECR1,SLX4,PPID,LPIN2,DTNBP1,MRPS27,TTC3,RMDN3,CDK12,CASP8AP2,SAP30,BRD4,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,LARGE,IFT140,XRCC4,MID1,NOSTRIN,B4GALT5,FARS2,KIF5C,OPA1,RPS6KA5,SFR1,ABL1,NEBL,CELF1,S100A14,DYNC2H1,NAV3,CLK2,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,PACS1,BMS1,GUF1,RETSAT,DDX50,COQ9,ORC5,SVIL,ATM,NDUFS5,ADK,DDIT3,IPO4,KAT6A,IMMP2L,PIGM,LETM1,LYRM4,ATRX,KMT2E,RARS2,PPIL1,PCYOX1L,DST,CNIH3,KANSL1,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,HCFC2,CARM1,CEP128,SRPK2,DEAF1,TNK2,SKAP2,SIRT6,MINA,MTHFD1L,PITPNB,COTL1,KMT2C,ST3GAL5,MPC1,ARPC3,TIMM44,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,MTCH1,DCTN3,ZCCHC8,VTA1,UBXN1,PCSK7,TIMM10,NAMPT,ELL,P3H1,WDR27,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,LIG4,SYT1,HERPUD1,UBE2E1,MGAT2,POP1,SYCP2L,BICD1,FSCN1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,CEMIP,PIGH,SMARCA4,PBX1,TBCCD1,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,NVL,CBR4,ADCK4,VCL,TMEM120B,UTP4,C6orf89,AUP1,MAML3,NARS2,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,ARMC4,IKZF4,KPNA3,HNRNPR,ARNTL,WDR73,FKBP5,NFRKB,TMCC1,TMEM33,DNAJC2,BCKDK,KLC4,CMTM8,PDE4B,VPS45,MED18,WDR26,ATF7IP,CHCHD10,GFM2,PEX7,SEC24C,DCTN4,FBL,ERI3,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,ZNF821,KDM5A,PSPC1,SCMH1,PDE2A,PEAK1,SERINC1,DAGLB,GADD45A,WDR35,VPS37B,POLR1C,ASCC1,WDR74,CSPP1,HLTF,CHAC1,COA1,NUP160,NOS1AP,AMBRA1,TOM1L1,SREBF2,NEK6,PMAIP1,NSRP1,SYN2,RASSF3,PDS5B,FNIP2,ZNF148,HRG,FXN,CDK6,GNL3,WLS,MCL1,RBM28,TMSB4X,SLC50A1,STOML2,DDX3X,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,MEF2C,TNNC1,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,RSF1,CLINT1,YARS2,ABCA7,DDX56,INTS7,MCM5,ALKBH8,ZNF326,NOC3L,ANP32B,CALN1,PRMT5,COQ3,TOMM34,EMC10,HMGCR,FADS1,PEA15,BDNF,TIMM8B,GTF2H3,COL17A1,MYO10,RB1CC1,SMARCD3,RYR2,IMPDH2,EVI5,ONECUT2,CPT1A,ABCF1,ZNF655,GTF2A1,LEMD3,CDK9,SURF1,GPN1,SENP3,WDR33,COG5,SPRED2,DNM3,FAM208B,ABCA3,MAP2K5,DDX18,NPAS2,ATP6V1A,ACTR3,PDK4,MYH9,NECAP1,TUBB6,SAFB2,STAM,HSPA1A,EEA1,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ATRIP,CEP63,MTHFD2L,LSM10,MALL,GARS,KRT7,STAMBP,NPM3,ATF7IP2,ARHGEF10,ATP6V0A1,TTC28,FKBP3,PES1,HLA-DMA,TAF2,CDC16,HIPK2,PEMT,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,NOL4L,SERINC5,INSIG2,XPC,SF3A3,ID2,JMJD6,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,SOX6,HNRNPM,DIS3L2,NUDC,CEP83,POLK,CEP295,MRPS10,FOXC1,RPA1,TRIB3,RARS,ETFDH,TOE1,POLE2,STX1A,ARID3B,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,ANAPC4,KDM4C,PPARGC1B,POLR1A,TFIP11,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,GIT2,BIRC2,DHX33,TRMU,XRCC2,UBAP2L,POLE3,RAN,MPST,SF3A1,TMPO,METTL1,CHD9,GCNT2,ABCC4,SKIV2L2,BAZ2A,KATNAL1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,MGST1,KIF16B,PEX1,CCDC28B,GLS,ZNF622,MSRA,TP53BP1,FAM206A,CCDC146,RAD51B,TNFRSF1A,C2CD5,CHMP4C,TTN,MCM6,STX8,HSD17B10,DNAH1,RNF40,ABCA5,PPIL2,GTF2H1,TIMELESS,ALDH18A1,TRAPPC9,TLE3,HOMER2,UTP15,BCS1L,RNH1,TRAPPC6B,SUPT5H,NR2F1,VAC14,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,PPP1R12B,BRSK2,NAPA,PRKAR2A,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,KDM1A,CAD,TMEM94,DNAJB6,ZDHHC6,HIRIP3,RNF2,HIBCH,CORO1A,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,GLTSCR2,CPOX,ENC1,NUP214,USP36,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,RBBP8,SIX5,TIMM17A,CLEC16A,ZNF436,PUS1,AP2S1,PPIL3,MIF4GD,ARFIP2,MAP1S,ZNF346,CSNK1A1,RMI1,IQGAP2,PTPN2,FAM50A,NDUFV1,ZNF561,ANXA7,CWC27,HIST2H3D,PRICKLE2,DDX31,FBXO31,PCK2,HSD17B12,GINS3,TPM4,TEX14,C11orf49,HIST1H4J,RHOT2,PIK3CB,CHCHD6,TMEM175,NEU1,ZRANB3,CENPP,POLR3G,GPC2,ZBTB8OS,ADAT2,SET,GLG1,MSH3,NDUFAF5,MYRF,GCSH,CGN,POLB,PRKAB2,DDX19A,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,MGA,RPS16,PAK1IP1,RNF111,VPS52,TRMT10A,CEP135,FUT11,SEH1L,DDN,SNU13,DPF3,SETD1B,ATG9A,NR6A1,NOL8,EYA3,CUX1,TCEB3,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,DNAH2,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,CELSR1,EGR1,ZHX3,ANKRD17,AK6,PID1,GTF2IRD1,CHD5,FKBP1A,NAV1,PI4KB,ZNF586,COPS3,GTF3C3,LPCAT1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIGMAR1,POLA1,KIAA0586,PTPN12,PLCB1,LYRM7,NSF,UBAP1,PMEPA1,D2HGDH,PURB,PEX13,IQSEC2,RTTN,AMOTL1,LIN28B,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,TERF2IP,PHC2,FLAD1,CHD7,TMEM184A,KDM2A,SHC1,UCHL5,GLYR1,NBEA,SSBP1,SERPINH1,KMT2A,RFC4,RFC3,PDK1,MTIF2,SFXN4,DLG4,MED16,PNN,POLG2,VDR,TAMM41,DNAJA3,H2AFX,ANXA2,MDN1,PDCD11,NOLC1,NCOR2,SCAMP3,UTP14A,C10orf2,TCF3,MRI1,NFX1,SLC25A12,RTN4,MLH1,CEP126,MON2,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,NEDD4,PTRF,TRIAP1,PMPCA,PHYKPL,COPS7B,RDX,UPF2,HARS2,EXOSC4,LARP4B,NT5M,MBTPS2,WDFY3,WDR18,APTX,PTK2,OASL,NOP58,MMAA,POLR2A,YIF1A,KLHL22,COL26A1,HNRNPH3,STX18,MYOM2,PGAM5,FEM1C,UBN1,NF1,KIF5A,CERS5,FANCD2,RCHY1,PLOD1,BCOR,SIRT2,SNAPC4,CUTC,SMARCB1,MRPS30,SRPRB,RTN1,ANAPC1,YLPM1,ANAPC10,HYAL1,RELB,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,PRKACB,TIMM50,ZBTB17,TRIM13,TXLNG,HDAC8,CAV1,ZSCAN2,SOX4,TAF9B,CHAF1A,UBTF,GEMIN5,RHOU,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,PQBP1,GALNT10,COPS6,NOCT,DMTF1,EMSY,TNRC6A,PIGN,CHST11,AK2,FN1,TAF1,SEC24D,PAX2,GPAT3,DPF2,ALG8,MED13L,XPO7,CMTM3,RHBDD1,ETFB,TOX4,CEP164,ATXN2,BANF1,BUD31,NRIP1,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,TBXAS1,WBSCR22,PSMA1,C19orf70,ISG15,DNAH14,MYBBP1A,INTS5,SDCCAG8,HK2,RRAGA,PDSS2,ASH1L,PCNT,MYO7A,SLC9B2,GBF1,SLC39A1,MIEF1,VPS18,BRE,CPSF3,TMEM14C,HTRA2,TMLHE,HN1,MCEE,ACSL5,COL5A2,PTBP2,PARP2,NLN,TOR1AIP2,RAB10,ZC3H12A,COPS5,SLC25A11,HEATR1,SCARB1,TNIK,H2AFJ,DBF4,LETMD1,PPHLN1,CLSTN2,MFSD10,SFI1,MAN1A1,MRPS11,CTNNBL1,KDELC1,SHMT2,AMOT,SLC25A1,MSX1,TEAD1,ARHGAP32,MEN1,SYMPK,HSPA1B,MFN2,RERE,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,MMP16,ARHGAP27,HRH1 |
| 3.159e-37 | -84.05 | heterocycle metabolic process | biological process | GO:0046483 | 4581 | 849 | 16441 | 2138 |
ASCC1,THOC5,WDR74,DCP1B,AARS2,HLTF,CCNL2,NT5C3A,ZNF44,HMOX2,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ATP5G2,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,HMBOX1,RNMT,UPP1,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,BDH2,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,BTBD9,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,PRMT5,ZNF518B,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,SMARCD3,IMPDH2,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,KPNA1,GTF2A1,NME7,CLASRP,RPL28,EHMT2,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,BPNT1,WDR33,ZNF516,TRERF1,DDX18,GTF2H2C,ATP6V1A,NPAS2,ISG20L2,NUP43,SAFB2,ZMAT2,MCM9,UBL5,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,PYCRL,WAC,ATRIP,INTS12,NT5C,MSH4,MTHFD2L,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,PES1,TAF2,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,RSRC1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,SOX6,HNRNPM,DIS3L2,DDX24,POLK,LDHA,ZNF467,PDE3B,FOXC1,DDX49,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,COX10,BIRC2,SCAF8,HNRNPLL,AMPD3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,PPCDC,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,SUMO3,BRCA1,ZNF91,DLST,MLLT10,GLS,HPRT1,TCF7L1,TP53BP1,CHD3,PER1,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,MCM6,FOXO1,PRSS3,HSD17B10,LAMTOR3,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,PDE10A,GTF2H1,CTR9,TIMELESS,ICE2,ALDH18A1,GMDS,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PGD,PWP1,PRPF40B,ATXN7,PALB2,SYNCRIP,TBPL1,ZNF430,DTD1,HMBS,DDX10,BCCIP,USP7,SART1,MPI,NDUFA5,ID1,PAPD4,SUCLG1,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,ZNF709,TNKS1BP1,PELP1,RPAIN,ZNF121,KDM1A,METTL16,CAD,ZBTB21,NRF1,DUS4L,NUP133,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,CPOX,NUP214,ZNF251,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,INTS9,PUS1,ZNF18,MED20,PPIL3,MUTYH,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,POLR1B,SNAPC5,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,TOP3A,HIST1H4J,EXOG,POLR3A,ZRANB3,POLR3G,SRBD1,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,AARS,UBR5,LPIN1,MGA,RPS16,RNF111,ME1,CHD2,MEIS3,TRMT10A,SEH1L,ZNF646,DPF3,SNU13,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,SON,DENND4A,SAP30BP,CLNS1A,GZF1,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,CCNB1IP1,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,PRPF31,LARS2,ZHX3,AK6,TATDN3,GTF2IRD1,PRPF39,CHD5,NDUFS7,HR,ZNF586,ENTPD5,SCAF1,COPS3,ATIC,MYC,SLC16A9,GTF3C3,CNOT4,PRPS1,TERF2,SCAF11,ADARB1,DDX28,EXOSC2,RREB1,PRIM2,PCCA,POLA1,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,HIF1A,SPEN,MED15,ZBTB12,ZCCHC6,PURB,DPEP1,UMPS,NCOR1,MACROD1,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,UROD,NDUFB5,OLA1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,PDE3A,NOP56,TERF2IP,CHD7,FLAD1,ZNF827,SLX4,PUS3,KDM2A,UCHL5,LPIN2,SSBP1,CMPK1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,DLG4,SATB2,MED16,PNN,SETD7,POLG2,DHX57,SNCA,ZBTB25,VDR,BAZ1A,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,FTSJ1,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,LIAS,IKBKAP,NOL3,FOXO3,MAD2L2,SFR1,DCTPP1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,HARS2,UPF2,COPS7B,CELF1,EXOSC4,YBX3,NT5M,PFKFB4,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,ADSL,APTX,KLF6,MMAA,NOP58,POLR2A,SLC23A2,ZFP62,DDX50,ZNF155,COQ9,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,ZNF76,PHF3,ATRX,KMT2E,RARS2,SLC52A3,FANCD2,RCHY1,ZNF107,PPIL1,BCOR,SLC29A1,SIRT2,SNAPC4,AHCYL2,EDC3,SMARCB1,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,POLR3B,NDUFA6,YARS,OGG1,LONP1,TRIP13,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,ITPA,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,CHAF1A,TAF9B,PAF1,GEMIN5,UBTF,GATA6,HLCS,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,EME1,ZC3H8,COPS6,ZNF397,NOCT,DMTF1,EMSY,AK2,ZCCHC8,TAF1,PAX2,DPF2,MED13L,SMG7,NAMPT,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,NRIP1,N4BP2,POLR1E,CPSF3L,MTHFD1,ZNF629,VOPP1,ZNF234,PDE4A,TSTA3,PPAT,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,ISG15,POP1,BICD1,MYBBP1A,INTS5,RRAGA,HK2,CDKAL1,ZFP90,TBL1X,PDE9A,AGO3,ZBTB24,NR2C2AP,TCF12,ASH1L,SMARCA4,PBX1,PUDP,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,MAML3,MCEE,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,METTL2A,GRHL3,METTL15,POU2F1,ATXN1,DKC1,PUSL1,BATF3,WARS,TPK1,RAD54B,ZC3H12A,ALAD,IKZF4,DUS3L,ADNP,HNRNPR,COPS5,ZNF557,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SULT1C2,SUPT6H,PDE4B,DBF4,PPHLN1,MED18,ATF7IP,CHCHD10,MRPS11,GART,CTNNBL1,SHMT2,ERI3,FBL,DMRT1,PKNOX1,TOP1,ARNTL2,PPP1R9B,MSX1,GPHN,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SULT4A1,SCMH1,ZNF324B,MARS,PDE2A,MEN1,ZNF407,SYMPK,TARS,RERE,ZNF221,CTIF,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1 |
| 3.329e-37 | -83.99 | nucleobase-containing compound metabolic process | biological process | GO:0006139 | 4395 | 822 | 16441 | 2138 |
ASCC1,THOC5,WDR74,DCP1B,AARS2,HLTF,CCNL2,NT5C3A,ZNF44,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ATP5G2,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,HMBOX1,RNMT,UPP1,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,PRMT5,ZNF518B,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,SMARCD3,IMPDH2,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,KPNA1,GTF2A1,NME7,CLASRP,RPL28,EHMT2,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,BPNT1,WDR33,ZNF516,TRERF1,DDX18,GTF2H2C,ATP6V1A,NPAS2,ISG20L2,NUP43,SAFB2,ZMAT2,MCM9,UBL5,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,WAC,ATRIP,INTS12,NT5C,MSH4,MTHFD2L,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,PES1,TAF2,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,RSRC1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,SOX6,HNRNPM,DIS3L2,DDX24,POLK,LDHA,ZNF467,PDE3B,FOXC1,DDX49,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,COX10,BIRC2,SCAF8,HNRNPLL,AMPD3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,PPCDC,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,SUMO3,BRCA1,ZNF91,DLST,MLLT10,GLS,HPRT1,TCF7L1,TP53BP1,CHD3,PER1,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,MCM6,FOXO1,HSD17B10,LAMTOR3,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,PDE10A,GTF2H1,CTR9,TIMELESS,ICE2,GMDS,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PGD,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,TBPL1,ZNF430,DTD1,DDX10,BCCIP,USP7,SART1,MPI,NDUFA5,ID1,PAPD4,SUCLG1,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,ZNF709,TNKS1BP1,PELP1,RPAIN,ZNF121,KDM1A,METTL16,CAD,ZBTB21,NRF1,DUS4L,NUP133,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,NUP214,ZNF251,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,INTS9,PUS1,ZNF18,MED20,PPIL3,MUTYH,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,POLR1B,SNAPC5,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,TOP3A,HIST1H4J,EXOG,POLR3A,ZRANB3,POLR3G,SRBD1,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,UBR5,AARS,LPIN1,MGA,RPS16,RNF111,CHD2,ME1,MEIS3,TRMT10A,SEH1L,ZNF646,DPF3,SNU13,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,SON,DENND4A,SAP30BP,CLNS1A,GZF1,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,CCNB1IP1,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,PRPF31,LARS2,ZHX3,AK6,TATDN3,GTF2IRD1,PRPF39,CHD5,NDUFS7,HR,ENTPD5,ZNF586,SCAF1,COPS3,ATIC,MYC,GTF3C3,CNOT4,PRPS1,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,ALKBH3,HIF1A,SPEN,MED15,ZBTB12,ZCCHC6,PURB,UMPS,NCOR1,MACROD1,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,NDUFB5,OLA1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,PDE3A,NOP56,TERF2IP,FLAD1,CHD7,ZNF827,SLX4,PUS3,KDM2A,UCHL5,LPIN2,SSBP1,CMPK1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,DLG4,SATB2,MED16,PNN,SETD7,POLG2,DHX57,SNCA,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,H2AFX,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,SFR1,DCTPP1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,HARS2,COPS7B,UPF2,CELF1,EXOSC4,YBX3,NT5M,PFKFB4,FAM120B,TSHZ1,TTLL5,APEX1,ADSL,APTX,KLF6,NOP58,POLR2A,SLC23A2,ZFP62,DDX50,ZNF155,COQ9,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,ZNF76,PHF3,ATRX,KMT2E,RARS2,FANCD2,RCHY1,ZNF107,PPIL1,BCOR,SLC29A1,SIRT2,SNAPC4,AHCYL2,EDC3,SMARCB1,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,POLR3B,NDUFA6,YARS,OGG1,LONP1,TRIP13,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,ITPA,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,CHAF1A,TAF9B,PAF1,GEMIN5,UBTF,GATA6,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,EME1,ZC3H8,COPS6,ZNF397,NOCT,DMTF1,EMSY,AK2,ZCCHC8,TAF1,PAX2,DPF2,MED13L,SMG7,NAMPT,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,NRIP1,N4BP2,POLR1E,CPSF3L,MTHFD1,ZNF629,VOPP1,ZNF234,PDE4A,TSTA3,PPAT,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,ISG15,POP1,BICD1,MYBBP1A,INTS5,RRAGA,HK2,CDKAL1,ZFP90,TBL1X,PDE9A,AGO3,ZBTB24,NR2C2AP,TCF12,ASH1L,SMARCA4,PBX1,PUDP,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,MAML3,MCEE,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,METTL2A,GRHL3,METTL15,POU2F1,ATXN1,DKC1,PUSL1,BATF3,WARS,RAD54B,ZC3H12A,IKZF4,DUS3L,ADNP,HNRNPR,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SULT1C2,SUPT6H,PDE4B,DBF4,PPHLN1,MED18,ATF7IP,CHCHD10,MRPS11,GART,CTNNBL1,ERI3,FBL,DMRT1,PKNOX1,TOP1,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SULT4A1,ZNF324B,SCMH1,MARS,PDE2A,MEN1,ZNF407,SYMPK,TARS,RERE,CTIF,ZNF221,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1 |
| 4.964e-37 | -83.59 | nucleoplasm | cellular component | GO:0005654 | 2802 | 573 | 17570 | 2233 |
ASCC1,THOC5,MRPL10,HLTF,CCNL2,CIAPIN1,SKI,NEK6,FAM222B,SREBF2,IKZF5,ZFHX3,NSRP1,PDS5B,ZNF148,FNIP2,KDM5C,SRRM2,ZNRD1,CDK6,RNMT,GNL3,EHMT1,NFIA,WDHD1,MCL1,MCM2,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,FIP1L1,RBP1,MEF2C,BANP,HERC2,TNNC1,EP400,KHDRBS1,RSF1,PDCD7,CLINT1,CDC73,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,NOC3L,PRMT5,TOMM34,GATAD2B,GTF2H3,WDR61,STAG1,ARID5B,IDH3G,USP10,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,KPNA1,GTF2A1,EHMT2,TRAP1,CDK9,GPN1,SENP3,WDR33,COG5,FAM208B,NPAS2,ISG20L2,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ACD,WAC,ATRIP,INTS12,MGLL,ZC3H3,LSM10,KMT2D,GARS,STAMBP,ZNF480,ATP6V0A1,MEF2D,CCNDBP1,PES1,TAF2,CDC16,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,HMGA2,NOL4L,SHQ1,XPC,SF3A3,ID2,JMJD6,AKT1S1,TRIM22,IP6K2,ZNF691,RSRC1,PSMF1,MBNL1,TADA3,SNW1,POLR3D,SUV39H2,TAF3,SOX6,HNRNPM,NUDC,VPS37A,POLK,ZC3H18,CCDC113,FOXC1,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,POLE2,ARID3B,ACOX1,AEN,NUDT22,ANAPC4,KDM4C,CYP24A1,CUL7,TRIM16,PPARGC1B,TFIP11,WDR13,POLR1A,CSNK2A1,GIT2,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,ANKRD11,UBAP2L,RAN,POLE3,ZMYM2,SF3A1,METTL1,CHD9,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,MED27,COL4A3BP,PSMG1,SUMO3,BRCA1,LSG1,CXADR,MLLT10,MSRA,TCF7L1,TP53BP1,CHD3,FAM206A,E2F4,ARL4A,RAD51B,PRPF4,TSEN2,MAGI1,MCM6,FOXO1,SMAD7,FAN1,ARID1B,RNF40,MBD2,VPS72,PPIL2,GTF2H1,CTR9,TIMELESS,ICE2,TLE3,SETD2,HAUS6,RNH1,SUPT5H,TCF7L2,NR2F1,PRPF40B,ATXN7,PALB2,SYNCRIP,SNAP23,TBPL1,PPP1R12B,USP7,SART1,ID1,ARID2,RBFOX2,PPP2R2A,TNKS1BP1,PELP1,RPAIN,KDM1A,CAD,NRF1,TMEM94,DNAJB6,RNF2,SPIDR,PRPF19,SKIV2L,KAT8,KDM3B,AKAP8L,ENC1,NUP214,EXO1,SMAD3,RBBP8,SIX5,TIMM17A,KLF4,ZNF436,INTS9,HSPB8,MED20,FAHD1,MUTYH,NIFK,ESCO1,MCM10,RFX1,AGO2,APRT,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,PTPN2,FAM50A,ZNF561,HIST2H3D,POLR1B,SNAPC5,GINS3,SMARCAD1,TOP3A,FERMT2,C11orf49,YIPF3,HIST1H4J,POLR3A,POLR3G,CENPP,ZBTB8OS,ADAT2,TAF4,SET,MSH3,RBPJ,TAF12,POLB,CUL4A,PRKAB2,PLRG1,PRKCA,UBR5,MGA,LPIN1,RNF111,PAK1IP1,CHD2,SNU13,SETD1B,NR6A1,EYA3,CUX1,TCEB3,HIST1H2BL,SUPT20H,SON,SAP30BP,CLNS1A,GZF1,DOT1L,OSBPL1A,SPOP,SKIL,TRRAP,CCNT1,LUC7L3,NSMCE1,BMI1,NMD3,PTPN14,C9orf78,WDR75,CELSR1,EGR1,DROSHA,ZHX3,PRPF31,AK6,PID1,GTF2IRD1,CHD5,HR,ZNF586,USPL1,MYC,COPS3,GTF3C3,TERF2,ADARB1,SCAF11,RREB1,PRIM2,POLA1,ARID1A,NELFA,PLCB1,SLC26A11,PHF6,ASCC3,ALKBH3,HIF1A,PMEPA1,SPEN,MED15,NCOR1,CNDP2,SMYD3,UROD,NDUFB5,POP5,FOSL2,HNRNPA3,RING1,TRIM66,NOP56,TERF2IP,PHC2,DECR1,SLX4,KDM2A,PPID,GLYR1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,ZBTB25,VDR,DNTTIP1,CAMK2D,SMARCC1,H2AFX,XRCC4,NOLC1,NCOR2,TCF3,MLH1,OPA1,IKBKAP,RPS6KA5,FOXO3,MAD2L2,ABL1,PTRF,COPS7B,CELF1,S100A14,CLK2,PXN,APEX1,WDFY3,WDR18,APTX,NOP58,POLR2A,HNRNPH3,ORC5,ATM,ADK,DDIT3,KAT6A,FEM1C,KMT2E,ATRX,UBN1,FANCD2,RCHY1,SNAPC4,SMARCB1,ANAPC1,KANSL1,YLPM1,SLC39A7,ANAPC11,ANAPC10,ZEB1,RELB,POLR3B,HCFC2,OGG1,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,DEAF1,SKAP2,SIRT6,HDAC8,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,GEMIN5,PAF1,EPN2,EIF4ENIF1,SUFU,GATA6,CC2D1B,PQBP1,CRCP,EME1,COPS6,ZC3H8,NOCT,DMTF1,TNRC6A,EMSY,TAF1,ZCCHC8,DPF2,MED13L,NAMPT,TOX4,CEP164,ELL,WDR27,ATXN2,BANF1,NRIP1,POLR1E,CPSF3L,XPO5,JMJD1C,ELP3,PSMA1,LIG4,UBE2E1,ISG15,POP1,SYCP2L,INTS5,FDPS,TBL1X,PFDN2,NR2C2AP,SNX27,ASH1L,PBX1,SMARCA4,SBDS,ZC3H13,RRN3,BRE,NVL,CPSF3,MAML3,PARP2,GRHL3,POU2F1,ATXN1,DKC1,UBR4,ZC3H12A,ARMC4,KPNA3,IKZF4,HNRNPR,COPS5,ARNTL,FKBP5,NFRKB,DNAJC2,TNIK,CMTM8,DBF4,PPHLN1,WDR26,ATF7IP,MED18,CTNNBL1,FBL,MICAL3,RPS6KB2,TOP1,KDM6B,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,KDM5A,PSPC1,SCMH1,MEN1,PEAK1,SYMPK,HSPA1B,RERE,GADD45A,CUL2,ZRANB2,NCBP2,MBD6,POLR1C,TATDN1,ARHGAP27,HRH1 |
| 1.413e-36 | -82.55 | nucleus | cellular component | GO:0005634 | 6737 | 1130 | 17570 | 2233 |
PTP4A1,THOC5,DPH1,ACTG1,DCP1B,MRPL10,NAT10,CCNL2,ZNF44,CIAPIN1,SKI,ZNF37A,PDZD2,FAM222B,IKZF5,ZFHX3,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,HMBOX1,RNMT,EHMT1,NFIA,WDHD1,SHISA5,MCM2,ZNF197,AHNAK,SSU72,RAD18,RUNX1,ZNF532,BANP,EPM2AIP1,PIK3R4,PDCD7,PARN,CDC73,RBM20,UBE3A,DHX37,APLF,MED24,TNPO3,GEMIN4,PABPC1,ANGPT2,MYB,NOM1,ZNF675,GATAD2B,IFRD1,WDR61,STAG1,ZNF587,ARID5B,IDH3G,USP10,TRIM37,SRA1,IRS1,TSR1,KPNA1,EHMT2,TRAP1,CCDC85B,SRP14,GTF2H2C,PAFAH1B1,ISG20L2,NUP43,ZMAT2,MCM9,UBL5,ZSWIM7,ACD,WAC,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,PMS1,KMT2D,ZNF480,CCNDBP1,MEF2D,DSP,KDM4B,ELP2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,IP6K2,TRIM22,RNASEH2B,ZNF691,PSMF1,SNW1,POLR3D,TAF3,NOP16,ANXA5,PTGS1,ZNF710,PNMA1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,UBC,ANXA1,NSD1,SRCAP,ACOX1,AEN,CYP24A1,CUL7,TRIM16,WDR13,NLE1,SCAF8,HNRNPLL,MAP2K3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,AEBP2,ATF4,MIOS,PPARG,CDK4,HSPA5,TSN,PSMG1,SUMO3,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,TCF7L1,CHD3,ARL4A,E2F4,AHNAK2,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,FOXO1,CLK1,FAN1,SMAD7,ZIC2,C1orf52,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,CTR9,ICE2,USP49,SETD2,HAUS6,METTL22,TCF7L2,PRPF40B,DTD1,PTP4A2,BCCIP,USP7,SART1,ID1,OLFM2,PAPD4,ARID2,SLC2A1,LAGE3,SSBP2,TIGD1,TNKS1BP1,URB1,ZNF121,NRF1,NUP133,SPIDR,IPO11,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,ZNF251,EXO1,KLF4,INTS9,HSPB8,MED20,FAHD1,MUTYH,ZNF507,NIFK,ESCO1,MCM10,RFX1,AGO2,ESRG,APRT,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SURF2,CPNE7,POLR1B,SNAPC5,TRNP1,FOXN3,SMARCAD1,TOP3A,FERMT2,RANGAP1,YIPF3,PALLD,POLR3A,NOL10,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,ZNF32,RBPJ,TAF12,NR2F2,XPO6,ZNF292,CUL4A,LUZP1,PRKCA,GABPB2,LPIN1,SUCLG2,DPH6,CHD2,SPAG6,ZNF646,ACADS,GDAP1,SUPT20H,HIST1H2BL,DENND4A,SON,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,TRRAP,CCNT1,NSMCE1,LUC7L3,HIC2,BLMH,BMI1,RFXAP,ZMAT3,NMD3,PRPF38B,C9orf78,JUP,PRPF31,CENPB,TATDN3,CRACR2A,PRPF39,PDCD5,MTUS1,FAM192A,HR,USPL1,NOVA2,SCAF1,MYC,PLEKHA2,CNOT4,CAV2,EXOSC2,ANAPC13,RREB1,PRIM2,RDH10,RAP1GAP2,ARID1A,NELFA,SLC26A11,ZNF850,PHF6,ASCC3,ALKBH3,HIF1A,SPEN,SRP68,MED15,BIVM,NCOR1,CNDP2,DHCR7,SMYD3,ZNF254,UROD,POP5,HNRNPA3,RING1,NOP56,BLOC1S2,DECR1,SLX4,PPID,LPIN2,DTNBP1,TTC3,RMDN3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,GNL1,SATB2,SETD7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,OPA1,RPS6KA5,SFR1,ABL1,ELP5,CELF1,S100A14,ERRFI1,NAV3,CLK2,PXN,TTLL5,APEX1,BMS1,KLF6,ZFP62,RETSAT,DDX50,ZNF155,ORC5,SVIL,ATM,APAF1,ADK,DDIT3,IPO4,KAT6A,ZNF76,LYRM4,ATRX,KMT2E,PPIL1,DST,KANSL1,JAZF1,ANAPC11,SLC39A7,GPATCH1,ZEB1,HCFC2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,ZNF195,SKAP2,SIRT6,MINA,COTL1,SGK2,KMT2C,EIF4ENIF1,HLCS,CC2D1B,CRCP,CLU,EME1,ZC3H8,ZCCHC8,SMG7,NAMPT,ELL,P3H1,ZNF354A,WDR27,ZCCHC7,ZNF629,ZNF234,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,UBE2E1,POP1,SYCP2L,APBB3,FAT1,FDPS,PFDN2,TBL1X,N4BP2L2,NR2C2AP,TCF12,SNX27,CEMIP,SMARCA4,PBX1,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,FHIT,TMEM120B,UTP4,C6orf89,MAML3,PRAME,GRHL3,ATXN1,POU2F1,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,IKZF4,KPNA3,HNRNPR,ZNF557,ARNTL,CEBPZ,FKBP5,NFRKB,RNF130,SMG1,TMEM33,DNAJC2,SUPT6H,CAMK1,CMTM8,MED18,IGF2BP2,WDR26,ATF7IP,PIP4K2A,DCTN4,ERI3,FBL,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,KDM6B,ARNTL2,PPP1R9B,KDM5B,FGF2,ZNF821,PSPC1,KDM5A,SCMH1,ZNF324B,PDE2A,PEAK1,EIF5B,ZNF221,GADD45A,AGTPBP1,POLR1C,NFKBIB,NIT1,ASCC1,WDR74,HLTF,NUP160,NOS1AP,PABPC4,SREBF2,NEK6,PMAIP1,NSRP1,RABGAP1L,PDS5B,WIZ,FNIP2,ZNF148,CDK6,GNL3,RFX2,MCL1,RBM28,SLC50A1,STOML2,DDX3X,SUPT4H1,BRCA2,ZNF266,FIP1L1,RBP1,LPP,MEF2C,TNNC1,HERC2,EP400,TRIP6,KHDRBS1,SIRT7,RSF1,CLINT1,SLC39A11,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,AGL,ZNF518B,TOMM34,SERBP1,GTF2H3,RB1CC1,TSPYL4,MYO10,PRDM16,STPG1,EPS15L1,ZNF512B,SMARCD3,IMPDH2,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,CLASRP,GTF2A1,CDK9,LEMD3,ZNF160,GPN1,CNOT6,SENP3,WDR33,COG5,FAM208B,ZNF516,MAP2K5,TRERF1,DDX18,NPAS2,MYH9,TUBB6,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ZKSCAN1,ERI1,ATRIP,NT5C,LSM10,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ATP6V0A1,FKBP3,FGFR1,PES1,TAF2,CDC16,HIPK2,FUS,BRCC3,ZBTB11,LAMA5,ANKS1A,YEATS2,NOL4L,ZNF786,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,MBNL1,RSRC1,POM121,KRI1,TADA3,SUV39H2,SOX6,HNRNPM,DIS3L2,NUDC,POLK,ARHGAP39,FRA10AC1,R3HDM2,ZNF467,UBE2K,FOXC1,RPA1,TRIB3,RARS,TOE1,BAZ2B,POLE2,ARID3B,SLC25A19,NUDT22,ANAPC4,KDM4C,GPBP1L1,POLR1A,TFIP11,PPARGC1B,NREP,CSNK2A1,RNF43,GIT2,BIRC2,DHX33,TRMU,XRCC2,UBAP2L,POLE3,RAN,ZNF85,ETV1,SF3A1,TMPO,METTL1,CHD9,SLC3A2,ZNF124,ZNF414,BAZ2A,SKIV2L2,MED27,NOL6,COL4A3BP,BRCA1,ZNF91,MGST1,ZNF622,MSRA,TP53BP1,FAM206A,EEFSEC,PER1,RAD51B,DLX2,TTN,MCM6,MEX3A,HES6,BARX2,ZFP36L1,RLF,RNF40,SAMD11,PPIL2,TIMELESS,GTF2H1,NAA38,CAMKK2,CRADD,PAXBP1,TLE3,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SYNCRIP,PALB2,SNAP23,IRAK2,TBPL1,PPP1R12B,ZNF430,HMBS,TESC,RNF114,RBFOX2,PPP2R2A,RSL1D1,ZNF83,ZNF709,RPAIN,PELP1,KDM1A,CAD,METTL16,ZBTB21,TMEM94,DNAJB6,IKBKB,HIRIP3,ZFP37,ETF1,RNF2,CORO1A,CTC1,SKIV2L,KAT8,WDR36,PCGF3,TUBA1A,DDX41,GLTSCR2,AKAP13,ENC1,NUP214,USP36,PUM3,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ZNF436,PUS1,ZNF18,ZNF589,PPIL3,PKIB,MIF4GD,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,FAM50A,SACS,ZNF561,ANXA7,CWC27,HIST2H3D,PRICKLE2,DDX31,FAM71E1,GINS3,ZNF654,ZMYM5,C11orf49,HIST1H4J,PIK3CB,CENPP,POLR3G,MKX,ZRANB3,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,MYRF,ITGB4,MIPOL1,POLB,MYCBP2,PRKAB2,DDX19A,PLRG1,TMEM109,UBR5,MGA,PAK1IP1,RNF111,TRMT10A,MEIS3,SEH1L,DDN,SNU13,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,DESI1,HSH2D,MAK16,SAP30BP,SKIL,ZNF81,CCNB1IP1,TXN2,PTPN14,WDR75,CELSR1,EGR1,DROSHA,ZHX3,ANKRD17,AK6,PID1,GTF2IRD1,CHD5,IGF2BP3,PRKCE,ZNF586,COPS3,GTF3C3,IGF2BP1,TERF2,SCAF11,ADARB1,DDX28,SIGMAR1,POLA1,PLCB1,ARIH2,ZNF425,SERF2,PMEPA1,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,AMOTL1,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,TRIM66,TERF2IP,PHC2,CHD7,ZNF827,PUS3,KDM2A,SHC1,UCHL5,GLYR1,SSBP1,KMT2A,RFC4,RFC3,MTIF2,MED16,PNN,VDR,DNAJA3,ZNF236,H2AFX,ALKBH1,ANXA2,MDN1,NOLC1,PDCD11,TROVE2,NCOR2,UTP14A,TCF3,MRI1,ZNF280C,NFX1,MYNN,RTN4,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,TMCO6,ZNF239,ZNF483,RGS17,COMMD9,PTRF,COPS7B,UPF2,EXOSC4,LARP4B,YBX3,FAM120B,TSHZ1,WDFY3,WDR18,APTX,PTK2,OASL,NOP58,POLR2A,HELZ,HNRNPH3,RNF138,BRWD3,LRRC41,STK4,PHF3,FEM1C,NF1,UBN1,CERS5,FANCD2,RCHY1,ZNF107,SIRT2,BCOR,CUTC,SNAPC4,SMARCB1,ANAPC1,YLPM1,ANAPC10,RELB,POLR3B,OGG1,LONP1,PRKACB,TRIP13,TIMM50,ELOF1,ZBTB17,TXLNG,ZNF680,CMIP,HDAC8,ZSCAN2,SOX4,SERGEF,TAF9B,CHAF1A,UBTF,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,MKL2,PQBP1,ZNF397,COPS6,NOCT,DMTF1,TNRC6A,EMSY,TAF1,PAX2,DPF2,CDIP1,MED13L,C11orf54,XPO7,CMTM3,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,NRIP1,POLR1E,CPSF3L,RANBP6,WBSCR22,PSMA1,WWC1,PRDM1,ISG15,MYBBP1A,ATAD5,INTS5,RRAGA,ZFP90,ZBTB24,ZNF706,ASH1L,SLC5A5,CSTA,ZSCAN5A,BRE,CAMTA2,ZNF142,CPSF3,ZNF460,HTRA2,HN1,MOSPD1,ACSL5,PTBP2,TFCP2,PARP2,SFSWAP,TOR1AIP2,C1orf174,WARS,RAD54B,ZC3H12A,PLIN2,ADNP,COPS5,SLC25A11,SRFBP1,HEATR1,USP11,TNIK,H2AFJ,DBF4,TKFC,PPHLN1,CTNNBL1,SHMT2,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MEN1,ZNF407,SYMPK,HSPA1B,RERE,ZNF708,ZNF330,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,ZAK,ARHGAP27,HRH1 |
| 1.817e-36 | -82.30 | cellular nitrogen compound metabolic process | biological process | GO:0034641 | 5148 | 927 | 16441 | 2138 |
GGT1,ASCC1,THOC5,WDR74,DCP1B,AARS2,MRPL10,HLTF,CCNL2,NT5C3A,ZNF44,HMOX2,SLC6A8,NUP160,PABPC4,SKI,ZNF37A,MMP7,SREBF2,IKZF5,ZFHX3,NSRP1,ATP5G2,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,PPM1K,HMBOX1,EIF4E3,RNMT,UPP1,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,BDH2,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,PLA2G12A,BTBD9,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,EIF2S2,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,MRPL21,PRMT5,ZNF518B,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,SMARCD3,ST6GALNAC3,IMPDH2,CPT1A,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,KPNA1,GTF2A1,GSTO2,NME7,CLASRP,RPL28,EHMT2,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,BPNT1,WDR33,SRP14,ZNF516,TRERF1,DDX18,GTF2H2C,PAFAH1B1,NPAS2,ATP6V1A,ISG20L2,NUP43,ST3GAL6,SAFB2,ZMAT2,MCM9,UBL5,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,PYCRL,WAC,ATRIP,INTS12,GSTA4,NT5C,MSH4,MTHFD2L,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,PES1,TAF2,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,PAM,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,RSRC1,PSMF1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,UNC13A,ZNF710,RPL22L1,SOX6,HNRNPM,DIS3L2,DDX24,POLK,LDHA,MRPS10,ZNF467,PDE3B,FOXC1,DDX49,UBC,ANXA1,MRPL36,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,KDM4C,SRM,GPBP1L1,PPARGC1B,TFIP11,POLR1A,SLC25A21,CSNK2A1,COX10,BIRC2,SCAF8,HNRNPLL,AMPD3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,PPCDC,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,MPST,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,COL4A3BP,NOL6,SUMO3,BRCA1,ODC1,ZNF91,DLST,MGST1,MLLT10,GLS,HPRT1,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,MCM6,FOXO1,HSD17B10,LAMTOR3,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,PDE10A,GTF2H1,CTR9,TIMELESS,ICE2,ALDH18A1,GMDS,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PGD,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,TBPL1,ZNF430,DTD1,HMBS,GGT7,DDX10,BCCIP,USP7,SART1,MPI,NDUFA5,ID1,PAPD4,SUCLG1,ARID2,LPCAT2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,LPCAT3,ZNF709,TNKS1BP1,PELP1,RPAIN,ZNF121,KDM1A,DENR,METTL16,CAD,ZBTB21,NRF1,DUS4L,NUP133,HIBCH,RNF2,ETF1,ZFP37,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,CPOX,NUP214,ZNF251,EIF3H,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ABHD3,ATG7,ZNF436,INTS9,PUS1,ZNF18,MED20,EIF2B3,PPIL3,MUTYH,ZNF507,DMGDH,NIFK,MCM10,AUH,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,SELT,POLR1B,SNAPC5,PCSK6,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,TOP3A,HIST1H4J,EXOG,NEU1,POLR3A,SMPDL3B,ZRANB3,POLR3G,SRBD1,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,EIF2S1,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,GCSH,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,AARS,UBR5,LPIN1,MGA,RPS16,RNF111,ME1,CHD2,MEIS3,TRMT10A,SEH1L,ZNF646,DPF3,SNU13,GDAP1,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,SON,DENND4A,SAP30BP,CLNS1A,GZF1,SKIL,DDAH2,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,XPNPEP1,CCNB1IP1,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,PRPF31,LARS2,ZHX3,AK6,TATDN3,GTF2IRD1,PRPF39,SSR4,CHD5,NDUFS7,IGF2BP3,HR,ZNF586,ENTPD5,SCAF1,COPS3,ATIC,MYC,SLC16A9,GTF3C3,CNOT4,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,DDX28,EXOSC2,RREB1,PRIM2,PCCA,POLA1,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,HIF1A,SPEN,SRP68,MED15,ZBTB12,ZCCHC6,PURB,DPEP1,UMPS,NCOR1,CNDP2,MACROD1,ZFHX2,CPT1C,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,UROD,NDUFB5,OLA1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,PDE3A,NOP56,TERF2IP,CHD7,FLAD1,ZNF827,SLX4,PUS3,ASNS,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,CMPK1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,DLG4,SATB2,MED16,PNN,SETD7,POLG2,DHX57,SNCA,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,FTSJ1,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,IKBKAP,NOL3,FOXO3,MAD2L2,SFR1,DCTPP1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,PHYKPL,HARS2,UPF2,COPS7B,CELF1,EXOSC4,YBX3,NT5M,FAM120B,PFKFB4,TSHZ1,TTLL5,APEX1,PSAT1,ADSL,APTX,KLF6,GUF1,MMAA,NOP58,POLR2A,SLC23A2,ZFP62,DDX50,ZNF155,COQ9,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,IMMP2L,ZNF76,PHF3,EIF3C,ATRX,KMT2E,RARS2,SLC52A3,CERS5,FANCD2,RCHY1,ZNF107,PPIL1,BCOR,SLC29A1,SIRT2,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,SRPRB,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,POLR3B,NDUFA6,YARS,OGG1,LONP1,TRIP13,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,ITPA,MINA,HDAC8,MTHFD1L,KMT2C,ZSCAN2,SOX4,ST3GAL5,CHAF1A,TAF9B,PAF1,GEMIN5,UBTF,GATA6,HLCS,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,EME1,ZC3H8,COPS6,ZNF397,NOCT,DMTF1,EMSY,AK2,ZCCHC8,TAF1,PAX2,DPF2,PCSK7,MED13L,SMG7,PHGDH,NAMPT,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,NRIP1,N4BP2,POLR1E,CPSF3L,MTHFD1,ZNF629,VOPP1,ZNF234,PDE4A,TSTA3,PPAT,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,LIG4,PSMA1,WWC1,PRDM1,EIF2A,CORIN,ISG15,POP1,BICD1,MYBBP1A,INTS5,RRAGA,HK2,CDKAL1,ZFP90,TBL1X,PDE9A,AGO3,ZBTB24,NR2C2AP,TCF12,ASH1L,SLC5A5,SMARCA4,PBX1,PUDP,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,HTRA2,MAML3,TMLHE,MCEE,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,METTL2A,GRHL3,MRRF,NLN,METTL15,ATXN1,POU2F1,DKC1,PUSL1,BATF3,WARS,TPK1,RAD54B,ZC3H12A,ALAD,DUS3L,IKZF4,ADNP,HNRNPR,COPS5,ZNF557,ARNTL,CEBPZ,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,BCKDK,SULT1C2,SUPT6H,PDE4B,DBF4,PPHLN1,MED18,ATF7IP,CHCHD10,GFM2,MRPS11,GART,CTNNBL1,SHMT2,ERI3,FBL,DMRT1,PKNOX1,TOP1,RPS6KB2,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SULT4A1,SCMH1,ZNF324B,MARS,PDE2A,MEN1,EIF5B,ZNF407,SYMPK,TARS,RERE,ZNF221,CTIF,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1 |
| 1.972e-36 | -82.21 | organelle part | cellular component | GO:0044422 | 8026 | 1297 | 17570 | 2233 |
PTP4A1,THOC5,ACTG1,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,CIAPIN1,SKI,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,RNMT,LIMA1,EHMT1,AP4B1,NFIA,KIF15,WDHD1,SHISA5,MCM2,PYCR1,AHNAK,RBSN,RAD18,SYNGR2,MPV17,RUNX1,TPM1,SLC25A26,BANP,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,CNST,DHX37,APLF,WDR60,MED24,TNPO3,GEMIN4,MRPL21,PABPC1,MYB,NOM1,RABEPK,GATAD2B,ALG6,WDR61,STAG1,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,CCDC85B,PDLIM5,RAB11FIP4,GTF2H2C,PAFAH1B1,VTI1A,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,RPGRIP1L,NDUFB3,SPG21,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PXK,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,ZNF480,CCNDBP1,MEF2D,SLC35D1,DSP,VPS53,ARHGAP21,KDM4B,ELP2,NSMCE2,ARL13B,POLR3E,HOXA3,RPS6KB1,CATSPERG,CEP170,RAB30,MAPT,HMGA2,SHQ1,ATG2B,GAS6,TRIM22,IP6K2,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,ANXA5,PTGS1,ACTR3B,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,ZC3H18,LDHA,CCDC113,UBC,MRPL36,ANXA1,NSD1,ACOX1,SRD5A3,AEN,UQCC1,CYP24A1,CUL7,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,ZMYM2,SLC25A23,DBN1,AEBP2,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,PSMG1,SUMO3,KRTCAP2,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,LSS,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,PRPF4,TSEN2,MAGI1,UQCC2,FOXO1,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ARID1B,SPIRE1,SUB1,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,PNPLA3,NIPSNAP1,WARS2,IFT43,SETD2,HAUS6,OBSCN,CYB5B,TCF7L2,PRPF40B,SNX24,SIL1,SH3PXD2A,BCCIP,USP7,SART1,ID1,SUCLG1,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,SLC2A1,RPS29,TNKS1BP1,RADIL,PPP1R9A,URB1,FDX1,NRF1,NUP133,CCDC40,MYH15,BCAP29,SPIDR,IPO11,PRPF19,KDM3B,AKAP8L,RAB7A,VIM,CA5B,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,HSPB8,MED20,FAHD1,MUTYH,PARD3,DMGDH,NIFK,ESCO1,KIZ,MCM10,HM13,AUH,RFX1,AGO2,APRT,RBM19,FOXP1,POGZ,HIST2H2AB,SLC25A20,TTC1,SURF2,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,YIPF3,EXOG,PALLD,POLR3A,DKK1,NOL10,TAF4,BCAS3,FNTB,USP20,RBPJ,TAF12,XPO6,KIF1B,CUL4A,PRKCSH,GYG1,PRKCA,LPIN1,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ACADS,GDAP1,EFHC1,CAMSAP2,SUPT20H,HIST1H2BL,SON,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,NSMCE1,ARL6IP5,LUC7L3,CFD,NRP1,BMI1,ZMAT3,NMD3,PRPF38B,C9orf78,JUP,PRPF31,LARS2,ST6GAL1,CENPB,DPM3,CRACR2A,SSR4,PRPF39,NDUFS7,MTUS1,HR,USPL1,MYC,PIGG,CAV2,FDFT1,EXOSC2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAP1GAP2,ARID1A,NELFA,SLC26A11,PHF6,ATP9B,CAT,SEC31A,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,POP5,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,DECR1,SLX4,PPID,LPIN2,DTNBP1,MRPS27,TTC3,RMDN3,CDK12,CASP8AP2,SAP30,BRD4,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,LARGE,IFT140,SLC4A7,XRCC4,MID1,NOSTRIN,B4GALT5,FARS2,KIF5C,OPA1,RPS6KA5,SFR1,ABL1,NEBL,CELF1,DYNC2H1,S100A14,CLK2,NAV3,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,PACS1,BMS1,GUF1,RETSAT,DDX50,COQ9,ORC5,SVIL,ATM,NDUFS5,ADK,DDIT3,IPO4,KAT6A,IMMP2L,PIGM,LETM1,LYRM4,KMT2E,ATRX,RARS2,PPIL1,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,SLC35C2,HCFC2,CARM1,CEP128,SRPK2,DEAF1,TNK2,SKAP2,SIRT6,TFPI,MINA,TMEM216,MTHFD1L,COTL1,PITPNB,KMT2C,ST3GAL5,MPC1,ARPC3,TIMM44,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,MTCH1,DCTN3,ZCCHC8,VTA1,UBXN1,PCSK7,TIMM10,NAMPT,ELL,P3H1,WDR27,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,LIG4,SYT1,HERPUD1,UBE2E1,MGAT2,POP1,SYCP2L,BICD1,FSCN1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,CEMIP,PIGH,SMARCA4,PBX1,TBCCD1,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,NVL,CBR4,ADCK4,VCL,TMEM120B,UTP4,C6orf89,AUP1,MAML3,NARS2,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,ARMC4,IKZF4,KPNA3,HNRNPR,ARNTL,WDR73,FKBP5,NFRKB,TMCC1,TMEM33,DNAJC2,BCKDK,KLC4,CMTM8,PDE4B,VPS45,MED18,WDR26,ATF7IP,CHCHD10,GFM2,PEX7,SEC24C,DCTN4,FBL,ERI3,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,ZNF821,KDM5A,PSPC1,SCMH1,PDE2A,PEAK1,SERINC1,DAGLB,GADD45A,WDR35,VPS37B,POLR1C,ASCC1,WDR74,CSPP1,HLTF,CHAC1,COA1,NUP160,NOS1AP,AMBRA1,TOM1L1,SREBF2,NEK6,PMAIP1,NSRP1,SYN2,RASSF3,PDS5B,FNIP2,ZNF148,HRG,FXN,CDK6,GNL3,WLS,MCL1,RBM28,TMSB4X,SLC50A1,STOML2,DDX3X,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,MEF2C,TNNC1,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,RSF1,CLINT1,YARS2,ABCA7,DDX56,INTS7,MCM5,ALKBH8,ZNF326,NOC3L,ANP32B,CALN1,PRMT5,COQ3,TOMM34,EMC10,HMGCR,FADS1,PEA15,BDNF,TIMM8B,GTF2H3,COL17A1,MYO10,RB1CC1,SMARCD3,RYR2,IMPDH2,EVI5,ONECUT2,CPT1A,ABCF1,ZNF655,GTF2A1,LEMD3,CDK9,SURF1,GPN1,SENP3,WDR33,COG5,SPRED2,DNM3,FAM208B,ABCA3,MAP2K5,DDX18,ATP6V1A,NPAS2,ACTR3,PDK4,MYH9,NECAP1,TUBB6,SAFB2,STAM,HSPA1A,EEA1,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ATRIP,CEP63,MTHFD2L,LSM10,MALL,GARS,KRT7,STAMBP,NPM3,ATF7IP2,ARHGEF10,ATP6V0A1,TTC28,FKBP3,PES1,HLA-DMA,TAF2,CDC16,HIPK2,PEMT,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,NOL4L,SERINC5,INSIG2,XPC,SF3A3,ID2,JMJD6,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,SOX6,HNRNPM,DIS3L2,NUDC,CEP83,POLK,CEP295,MRPS10,FOXC1,RPA1,TRIB3,RARS,ETFDH,TOE1,POLE2,STX1A,ARID3B,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,ANAPC4,KDM4C,PPARGC1B,POLR1A,TFIP11,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,GIT2,BIRC2,DHX33,TRMU,XRCC2,UBAP2L,POLE3,RAN,MPST,SF3A1,TMPO,FLNC,METTL1,CHD9,GCNT2,ABCC4,SKIV2L2,BAZ2A,KATNAL1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,MGST1,KIF16B,PEX1,CCDC28B,GLS,ZNF622,MSRA,TP53BP1,FAM206A,CCDC146,RAD51B,TNFRSF1A,C2CD5,CHMP4C,TTN,MCM6,STX8,HSD17B10,DNAH1,RNF40,ABCA5,PPIL2,GTF2H1,TIMELESS,ALDH18A1,TRAPPC9,TLE3,HOMER2,UTP15,BCS1L,RNH1,TRAPPC6B,SUPT5H,NR2F1,VAC14,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,PPP1R12B,BRSK2,NAPA,PRKAR2A,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,KDM1A,CAD,TMEM94,DNAJB6,ZDHHC6,HIRIP3,RNF2,HIBCH,CORO1A,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,GLTSCR2,CPOX,ENC1,NUP214,USP36,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,RBBP8,SIX5,TIMM17A,CLEC16A,ZNF436,PUS1,AP2S1,PPIL3,MIF4GD,ARFIP2,MAP1S,ZNF346,CSNK1A1,RMI1,IQGAP2,PTPN2,FAM50A,NDUFV1,ZNF561,ANXA7,CWC27,HIST2H3D,PRICKLE2,DDX31,FBXO31,PCK2,HSD17B12,GINS3,TPM4,TEX14,C11orf49,HIST1H4J,RHOT2,PIK3CB,CHCHD6,TMEM175,NEU1,ZRANB3,CENPP,POLR3G,TMEM237,GPC2,ZBTB8OS,ADAT2,SET,GLG1,MSH3,NDUFAF5,MYRF,GCSH,CGN,POLB,PRKAB2,DDX19A,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,MGA,RPS16,PAK1IP1,RNF111,VPS52,TRMT10A,CEP135,FUT11,SEH1L,DDN,SNU13,DPF3,SETD1B,ATG9A,NR6A1,NOL8,EYA3,CUX1,TCEB3,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,DNAH2,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,CELSR1,EGR1,ZHX3,ANKRD17,AK6,PID1,GTF2IRD1,CHD5,FKBP1A,NAV1,PI4KB,ZNF586,COPS3,GTF3C3,LPCAT1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIGMAR1,POLA1,KIAA0586,PTPN12,PLCB1,LYRM7,DAGLA,NSF,PMEPA1,UBAP1,D2HGDH,PURB,PEX13,IQSEC2,RTTN,AMOTL1,LIN28B,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,TERF2IP,PHC2,FLAD1,CHD7,TMEM184A,KDM2A,SHC1,UCHL5,GLYR1,NBEA,SSBP1,SERPINH1,KMT2A,RFC4,RFC3,CFAP221,PDK1,MTIF2,SFXN4,WDPCP,DLG4,MED16,PNN,POLG2,TAMM41,VDR,DNAJA3,H2AFX,ANXA2,MDN1,PDCD11,NOLC1,NCOR2,SCAMP3,UTP14A,C10orf2,MRI1,TCF3,NFX1,SLC25A12,RTN4,MLH1,CEP126,MON2,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,NEDD4,PTRF,TRIAP1,PMPCA,PHYKPL,COPS7B,RDX,UPF2,HARS2,EXOSC4,LARP4B,NT5M,MBTPS2,WDFY3,WDR18,APTX,PTK2,OASL,NOP58,MMAA,POLR2A,YIF1A,KLHL22,COL26A1,HNRNPH3,STX18,MYOM2,PGAM5,FEM1C,UBN1,NF1,KIF5A,CERS5,FANCD2,RCHY1,PLOD1,BCOR,SIRT2,SNAPC4,CUTC,SMARCB1,MRPS30,SRPRB,RTN1,ANAPC1,YLPM1,ANAPC10,HYAL1,RELB,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,PRKACB,TIMM50,ZBTB17,TRIM13,TXLNG,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,TAF9B,CHAF1A,UBTF,GEMIN5,RHOU,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,PQBP1,GALNT10,COPS6,NOCT,DMTF1,EMSY,TNRC6A,CHST11,PIGN,AK2,FN1,TAF1,SEC24D,PAX2,GPAT3,DPF2,ALG8,MED13L,XPO7,CMTM3,RHBDD1,ETFB,TOX4,CEP164,ATXN2,BANF1,BUD31,NRIP1,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,TBXAS1,WBSCR22,PSMA1,C19orf70,ISG15,DNAH14,MYBBP1A,INTS5,SDCCAG8,HK2,RRAGA,PDSS2,ASH1L,PCNT,MYO7A,SLC9B2,GBF1,SLC39A1,MIEF1,VPS18,BRE,CPSF3,TMEM14C,HTRA2,HN1,TMLHE,MCEE,ACSL5,COL5A2,PTBP2,PARP2,NLN,TOR1AIP2,RAB10,ZC3H12A,COPS5,SLC25A11,HEATR1,SCARB1,TNIK,H2AFJ,DBF4,LETMD1,PPHLN1,CLSTN2,MFSD10,SFI1,MAN1A1,MRPS11,CTNNBL1,KDELC1,SHMT2,AMOT,SLC25A1,MSX1,TEAD1,ARHGAP32,MEN1,SYMPK,NAPEPLD,HSPA1B,MFN2,RERE,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,MMP16,ARHGAP27,HRH1 |
| 2.462e-36 | -81.99 | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | 827 | 239 | 17758 | 2279 |
ZNF292,MYCBP2,PHF3,ATRX,PTPRA,CSNK2A1,HLTF,PRKCA,NUP160,UBR5,SCAF8,ZNF804A,DST,RAP1A,ZFHX3,RABGAP1L,ANAPC10,PDS5B,MAD1L1,ZEB1,ZNF148,KIAA0922,CEP135,ZMYM2,PRKACB,PTPRK,SRPK2,VPS13B,CHD9,SKAP2,SKIV2L2,PTPRM,TFPI,CUX1,WDHD1,CAMSAP2,BRCA1,SON,ST3GAL5,CRYBG3,GNAI1,SPOP,SLC7A1,BRCA2,TRRAP,TP53BP1,CTAGE5,SEMA3C,RUNX1,USP15,SEC24D,ANKRD17,ZHX3,LARS2,SLK,TRIO,PIK3R4,SMAD7,MED13L,TGFBR2,RLF,CLINT1,PARN,IGF2BP3,NAMPT,UBE3A,ATXN2,MBD2,MYC,SYNJ2,NRIP1,CNOT4,AKAP11,CAV2,ADARB1,SIK3,BDNF,IFRD1,LAMC1,CRADD,STAG1,PRIM2,RB1CC1,MYO10,PCCA,ARID5B,SETD2,WWC1,PTPN12,EVI5,AGAP1,EHBP1,TRIM37,MTR,UBE2E1,TCF7L2,IRS1,ASCC3,SPAG9,BICD1,KIDINS220,KIAA0355,HIF1A,ZZEF1,FAT1,SPEN,ARHGAP12,TBL1X,FNBP1L,PDLIM5,DDX10,MAP2K4,N4BP2L2,COG5,USP7,DMXL2,TCF12,SPRED2,ID1,PCNT,PAFAH1B1,RBFOX2,C16orf45,DDR2,PPP2R2A,SSBP2,PIBF1,GBF1,STAM,FLNB,NUP133,NVL,DNAJB6,SOCS6,RNF2,MGLL,VCL,PRMT3,SEC24A,KDM3B,PMS1,MPP6,FAM172A,COL5A2,MTIF2,ARHGEF10,PCMT1,R3HDM1,ATXN1,SATB2,GALK2,AKAP13,MARCH6,ENC1,TTC28,STK10,ERC1,SMAD3,BAZ1A,RANBP2,CDC16,KPNA3,ADNP,CLEC16A,WDR7,SLC4A7,MDN1,ZBTB11,XRCC4,TSPAN5,ANKS1A,CEP170,MID1,PARD3,TMCC1,NCOR2,DNAJC2,AUH,DBF4,TRAK1,SLC25A12,KIF5C,FARS2,WDR37,BHLHE40,TGFB2,OPA1,CSNK1A1,FOXO3,MBNL1,GIGYF2,PIP4K2A,NEDD4,PTPN2,SNW1,SACS,PVRL3,TANK,LTN1,UPF2,RDX,MAP3K14,LARP4B,SAMD4A,MICAL3,NAV3,TOP1,DNMBP,KDM5B,WDFY3,FGF2,CRIM1,TEAD1,FOXN3,KDM5A,ANKMY2,FERMT2,RSBN1,PTK2,R3HDM2,PPIP5K2,KLF6,DKK1,SLC23A2,CTIF,OXSR1,BAZ2B,HELZ,HNRNPH3,CUL2,TAF4,ORC5,MSH3,PTPN4,RBPJ,NR2F2,XPO6,KDM4C,KAT6A |
| 2.464e-36 | -81.99 | membrane-bounded organelle | cellular component | GO:0043227 | 11730 | 1744 | 17570 | 2233 |
PTP4A1,GGT1,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,SBF2,CCNL2,ZNF44,HMOX2,ABHD6,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,RNMT,EHMT1,AP4B1,NFIA,WDHD1,C5AR1,SHISA5,MCM2,ZNF197,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,RUNX1,SLC25A26,ZNF532,BANP,EPM2AIP1,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,RBM20,CNST,UBE3A,DHX37,APLF,WDR60,MED24,TNPO3,GEMIN4,MRPL21,PABPC1,PPA1,ANGPT2,MYB,NOM1,RABEPK,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,ATAT1,USP10,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,RPL28,EHMT2,TRAP1,CCDC85B,KIAA0196,BPNT1,SRP14,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,SUGCT,VTI1A,DDR2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,ESAM,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,LRRC75A-AS1,ZNF480,CCNDBP1,MEF2D,GSTCD,SLC35D1,DSP,VPS53,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,SNW1,POLR3D,TAF3,NOP16,ACOT11,ANXA5,PTGS1,ZNF710,ACTR3B,PNMA1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,UQCC1,CYP24A1,CUL7,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,HNRNPLL,MAP2K3,ECM1,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,AEBP2,ATF4,MIOS,PPARG,CDK4,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,LAMA2,KRTCAP2,KCNH2,DLST,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,PNPLA3,SNX29,NIPSNAP1,WARS2,USP49,HAUS6,SETD2,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,TTC38,SNX24,SIL1,DTD1,PTP4A2,BCCIP,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,UPK3B,PAPD4,ARID2,SLC48A1,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,URB1,ZNF121,FDX1,ANKRD13A,NRF1,IDI1,NUP133,BCAP29,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,RAB7A,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,KLF4,INTS9,HSPB8,MED20,FAHD1,MUTYH,ZNF507,DMGDH,NIFK,ESCO1,MINK1,MCM10,HM13,AUH,RFX1,AGO2,ESRG,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,SMPDL3B,DKK1,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,S100A10,ZFYVE28,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,CLNS1A,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,XPNPEP1,NRP1,BLMH,BMI1,RFXAP,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,CENPB,DPM3,CRACR2A,SSR4,PRPF39,PDCD5,NDUFS7,MTUS1,TECTA,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAP1GAP2,RAP1B,ARID1A,NELFA,SLC26A11,ZNF850,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,PPID,LPIN2,MRPS27,DTNBP1,TTC3,RMDN3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,TRAF3,TBXA2R,SETD6,XRCC4,VWA8,NOSTRIN,BRAF,B4GALT5,FARS2,RCAN1,OPA1,RPS6KA5,SFR1,ABL1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,LYRM4,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,ZNF195,SKAP2,SIRT6,TFPI,ARRDC3,MINA,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,MPC1,ARPC3,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CLU,EME1,ZC3H8,DCAF5,MTCH1,ZCCHC8,VTA1,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,ZNF354A,WDR27,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,ZNF629,ZNF234,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,SYT1,HERPUD1,UBE2E1,MGAT2,POP1,APBB3,SYCP2L,BICD1,FSCN1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,CEMIP,TNXB,PIGH,SMARCA4,PBX1,COBLL1,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,CBR4,FHIT,ADCK4,VCL,TMEM120B,UTP4,GNG5,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,FKBP5,NFRKB,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,CMTM8,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,IGF2BP2,WDR26,SOGA1,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,DCTN4,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,ZNF324B,SCMH1,PDE2A,PEAK1,TMEM187,EIF5B,ZNF221,SERINC1,DAGLB,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,GNB3,ASCC1,WDR74,HLTF,CHAC1,NT5C3A,COA1,NUP160,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RABGAP1L,PDS5B,WIZ,FNIP2,ZNF148,HRG,LYRM5,FXN,CDK6,WLS,GNL3,RFX2,MSRB3,MCL1,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,LPP,MEF2C,TNNC1,HERC2,EP400,TRIP6,KHDRBS1,SLK,SIRT7,PRAF2,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,COQ3,AGL,TOMM34,SERBP1,EMC10,HMGCR,FADS1,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,GPN1,ADGRE5,SENP3,CNOT6,WDR33,COG5,SPRED2,FAM208B,DNM3,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,NPAS2,ATP6V1A,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,TMEM150C,PRKD3,BCAS2,ABCA12,ZKSCAN1,ERI1,FMNL1,ATRIP,NT5C,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ATP6V0A1,FKBP3,FGFR1,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,NOL4L,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,SUV39H2,GATC,ARHGAP1,SOX6,HNRNPM,LYPLA2,DIS3L2,ULBP1,NUDC,FGF9,CEP83,CLYBL,POLK,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,ZNF467,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,RARS,ETFDH,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLC25A19,PSAP,GPAM,NUDT22,ANAPC4,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,MFGE8,NREP,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,GIT2,BIRC2,DHX33,TRMU,XRCC2,UBAP2L,ZNF85,POLE3,RAN,ETV1,MPST,SF3A1,CDC37,TMPO,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,ZNF414,BAZ2A,HARS,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,KIF16B,PEX1,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,EEFSEC,FAM206A,TNFRSF1A,RAD51B,DLX2,C2CD5,CHMP4C,XYLB,AOC3,OXNAD1,TTN,SARS,MCM6,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,RLF,RNF40,ABCA5,SAMD11,PPIL2,GTF2H1,TIMELESS,ALDH18A1,GMDS,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,TBPL1,ZNF430,PPP1R12B,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,NDUFA5,RBFOX2,LPCAT2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,METTL16,CAD,ZBTB21,TMEM94,DNAJB6,FSIP2,ZDHHC6,IKBKB,HIRIP3,RNF2,ETF1,ZFP37,HIBCH,CORO1A,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,TUBA1A,DDX41,NARS,GLTSCR2,THSD4,CPOX,AKAP13,ENC1,NUP214,USP36,TMEM186,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,RBBP8,SIX5,TIMM17A,ZNF333,CLEC16A,ZNF436,PUS1,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,PKIB,UNC13D,MIF4GD,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,HIST2H3D,PRICKLE2,GREB1,DDX31,CD44,PCK2,HSD17B12,FAM71E1,GINS3,ZNF654,ZMYM5,TPM4,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,CHCHD6,TMEM175,NEU1,ARMC3,ZRANB3,POLR3G,CENPP,MKX,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,POLB,PRDX6,PRKAB2,DDX19A,PLRG1,TMEM109,IKBIP,RAC3,AARS,UBR5,MGA,RPS16,PAK1IP1,RNF111,VPS52,ME1,MEIS3,PRADC1,TRMT10A,FUT11,SEH1L,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,TCEB3,CUX1,DESI1,HSH2D,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,ZNF81,VPS13D,SEMA3C,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,AK6,GTF2IRD1,PID1,CCDC47,CHD5,ANXA10,IGF2BP3,PRKCE,FKBP1A,PI4KB,ZNF586,ENTPD5,COPS3,ATIC,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIGMAR1,POLA1,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,DAGLA,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,PTCD2,AMOTL1,CCDC58,LIN28B,ZBTB37,RIBC2,URB2,NDUFB5,OLA1,SPATS2L,FOSL2,SLC25A44,AP1B1,TRIM66,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,RFC4,MPP6,RFC3,PDK1,MTIF2,SFXN4,DLG4,MED16,PNN,POLG2,STK10,DHX57,CPED1,TAMM41,VDR,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,LIAS,MON2,IKBKAP,NOL3,GDPD5,REEP5,FOXO3,MAD2L2,TMCO6,NEDD4,ZNF239,ZNF483,RGS17,COMMD9,PTRF,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,LARP4B,NT5M,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,PTK2,APTX,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,ZDHHC11,COL26A1,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,STK4,MVK,PHF3,FEM1C,UBN1,NF1,PTPRA,CERS5,FANCD2,RCHY1,PLOD1,ZNF107,BCOR,SIRT2,SNAPC4,CUTC,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ANAPC1,RAP1A,YLPM1,ZNHIT6,ANAPC10,RELB,HYAL1,POLR3B,PCOLCE2,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,LAMA4,ZBTB17,TRIM13,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,HDAC8,CAV1,ZSCAN2,SOX4,SERGEF,CHAF1A,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,SUFU,GATA6,TRMT5,DNAJC1,MKL2,PQBP1,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,TNRC6A,LDAH,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,MCAM,ATXN2,BANF1,BUD31,GLTP,NRIP1,POLR1E,CPSF3L,VOPP1,RANBP6,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,C19orf70,ISG15,MYBBP1A,ATAD5,INTS5,RRAGA,HK2,PTRH2,ZFP90,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,MMRN2,SLC5A5,MYO7A,FAM210A,SLC9B2,CSTA,PUDP,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,BRE,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,WARS,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,ECHDC1,TNIK,SULT1C2,C17orf80,OXLD1,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,MFSD10,HDDC2,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,DSG2,KDELC1,SHMT2,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,PREPL,ZAK,MMP16,ARHGAP27,HRH1 |
| 2.877e-35 | -79.53 | cellular aromatic compound metabolic process | biological process | GO:0006725 | 4597 | 844 | 16441 | 2138 |
ASCC1,THOC5,WDR74,DCP1B,AARS2,HLTF,CCNL2,NT5C3A,ZNF44,HMOX2,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ATP5G2,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,HMBOX1,RNMT,UPP1,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,BDH2,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,BTBD9,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,PRMT5,ZNF518B,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,SMARCD3,IMPDH2,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,KPNA1,GTF2A1,NME7,CLASRP,RPL28,EHMT2,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,BPNT1,WDR33,ZNF516,TRERF1,DDX18,GTF2H2C,NPAS2,ATP6V1A,ISG20L2,NUP43,SAFB2,ZMAT2,MCM9,UBL5,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,WAC,ATRIP,INTS12,NT5C,MSH4,MTHFD2L,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,PES1,TAF2,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,TGFB2,RSRC1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,SOX6,HNRNPM,DIS3L2,DDX24,POLK,LDHA,ZNF467,PDE3B,FOXC1,DDX49,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,COX10,BIRC2,SCAF8,HNRNPLL,AMPD3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,PPCDC,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,SUMO3,BRCA1,ZNF91,DLST,MLLT10,GLS,HPRT1,TCF7L1,TP53BP1,CHD3,PER1,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,MCM6,FOXO1,PRSS3,HSD17B10,LAMTOR3,SMAD7,FAN1,HES6,BARX2,ZFP36L1,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,PDE10A,GTF2H1,CTR9,TIMELESS,ICE2,GMDS,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PGD,PWP1,PRPF40B,ATXN7,PALB2,SYNCRIP,TBPL1,ZNF430,DTD1,HMBS,DDX10,BCCIP,USP7,SART1,MPI,NDUFA5,ID1,PAPD4,SUCLG1,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,ZNF709,TNKS1BP1,PELP1,RPAIN,ZNF121,KDM1A,METTL16,CAD,ZBTB21,NRF1,DUS4L,NUP133,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,CPOX,NUP214,ZNF251,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,INTS9,PUS1,ZNF18,MED20,PPIL3,MUTYH,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,POLR1B,SNAPC5,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,TOP3A,HIST1H4J,EXOG,POLR3A,ZRANB3,POLR3G,SRBD1,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,POLB,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,AARS,UBR5,LPIN1,MGA,RPS16,RNF111,ME1,CHD2,MEIS3,TRMT10A,SEH1L,ZNF646,DPF3,SNU13,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,DENND4A,SON,SAP30BP,CLNS1A,GZF1,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,CCNB1IP1,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,PRPF31,LARS2,ZHX3,AK6,TATDN3,GTF2IRD1,PRPF39,CHD5,NDUFS7,HR,ZNF586,ENTPD5,SCAF1,COPS3,ATIC,MYC,SLC16A9,GTF3C3,CNOT4,PRPS1,TERF2,SCAF11,ADARB1,DDX28,EXOSC2,RREB1,PRIM2,AOC2,POLA1,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,HIF1A,SPEN,MED15,ZBTB12,ZCCHC6,PURB,SQLE,UMPS,NCOR1,MACROD1,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,UROD,NDUFB5,OLA1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,PDE3A,NOP56,TERF2IP,CHD7,FLAD1,ZNF827,SLX4,PUS3,KDM2A,UCHL5,LPIN2,SSBP1,CMPK1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,DLG4,SATB2,MED16,PNN,SETD7,POLG2,DHX57,SNCA,ZBTB25,VDR,BAZ1A,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,FTSJ1,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,MRI1,ZNF280C,NFX1,FARS2,MYNN,MLH1,IKBKAP,NOL3,FOXO3,MAD2L2,SFR1,DCTPP1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,HARS2,UPF2,COPS7B,CELF1,EXOSC4,YBX3,NT5M,PFKFB4,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,ADSL,APTX,KLF6,MMAA,NOP58,POLR2A,SLC23A2,ZFP62,DDX50,ZNF155,COQ9,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,ZNF76,PHF3,ATRX,KMT2E,RARS2,FANCD2,RCHY1,ZNF107,PPIL1,BCOR,SLC29A1,SIRT2,SNAPC4,AHCYL2,EDC3,SMARCB1,YLPM1,JAZF1,MYH3,RELB,ZEB1,GPATCH1,POLR3B,NDUFA6,YARS,OGG1,LONP1,TRIP13,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,ITPA,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,CHAF1A,TAF9B,PAF1,GEMIN5,UBTF,GATA6,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,EME1,ZC3H8,ZNF397,COPS6,NOCT,DMTF1,EMSY,AK2,ZCCHC8,TAF1,PAX2,DPF2,MED13L,SMG7,NAMPT,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,NRIP1,N4BP2,POLR1E,CPSF3L,MTHFD1,ZNF629,VOPP1,ZNF234,PDE4A,TSTA3,PPAT,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,ISG15,POP1,BICD1,MYBBP1A,INTS5,RRAGA,HK2,CDKAL1,ZFP90,TBL1X,PDE9A,AGO3,ZBTB24,NR2C2AP,TCF12,ASH1L,SLC5A5,SMARCA4,PBX1,PUDP,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,MAML3,MCEE,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,GRHL3,METTL2A,METTL15,POU2F1,ATXN1,DKC1,PUSL1,BATF3,WARS,TPK1,RAD54B,ZC3H12A,ALAD,IKZF4,DUS3L,ADNP,HNRNPR,COPS5,ZNF557,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SULT1C2,SUPT6H,PDE4B,DBF4,PPHLN1,MED18,ATF7IP,CHCHD10,MRPS11,GART,CTNNBL1,SHMT2,ERI3,FBL,DMRT1,PKNOX1,TOP1,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SULT4A1,SCMH1,ZNF324B,MARS,PDE2A,MEN1,ZNF407,SYMPK,TARS,RERE,ZNF221,CTIF,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1 |
| 3.884e-34 | -76.93 | organic cyclic compound metabolic process | biological process | GO:1901360 | 4823 | 872 | 16441 | 2138 |
ASCC1,THOC5,WDR74,DCP1B,AARS2,CACNA1H,HLTF,CCNL2,NT5C3A,ZNF44,HMOX2,NUP160,PABPC4,SKI,ZNF37A,SREBF2,IKZF5,ZFHX3,NSRP1,ATP5G2,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,HMBOX1,RNMT,UPP1,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,BDH2,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,BTBD9,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,PRMT5,ZNF518B,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,SMARCD3,IMPDH2,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,KPNA1,GTF2A1,NME7,CLASRP,RPL28,EHMT2,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,BPNT1,WDR33,ZNF516,TRERF1,DDX18,GTF2H2C,NPAS2,ATP6V1A,ISG20L2,NUP43,SAFB2,ZMAT2,MCM9,UBL5,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,PYCRL,WAC,ATRIP,INTS12,NT5C,MSH4,MTHFD2L,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,PES1,TAF2,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,INSIG2,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,TGFB2,RSRC1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,SOX6,HNRNPM,DIS3L2,DDX24,POLK,LDHA,ZNF467,PDE3B,FOXC1,DDX49,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,SRD5A3,AEN,KDM4C,CYP24A1,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,COX10,BIRC2,SCAF8,HNRNPLL,AMPD3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,PPCDC,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,SUMO3,BRCA1,ZNF91,DLST,MLLT10,GLS,LSS,HPRT1,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,MCM6,FOXO1,PRSS3,HSD17B10,LAMTOR3,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,PDE10A,GTF2H1,CTR9,TIMELESS,ICE2,ALDH18A1,GMDS,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PGD,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,TBPL1,ZNF430,DTD1,HMBS,DDX10,BCCIP,USP7,SART1,MPI,NDUFA5,ID1,PAPD4,SUCLG1,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,ZNF709,TNKS1BP1,PELP1,RPAIN,ZNF121,FDX1,KDM1A,METTL16,CAD,ZBTB21,NRF1,IDI1,DUS4L,NUP133,RNF2,ETF1,ZFP37,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,CPOX,NUP214,ZNF251,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,INTS9,PUS1,ZNF18,MED20,PPIL3,MUTYH,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,POLR1B,HSD17B12,SNAPC5,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,TOP3A,HIST1H4J,EXOG,POLR3A,ZRANB3,POLR3G,SRBD1,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,UBR5,AARS,LPIN1,MGA,RPS16,RNF111,ME1,CHD2,MEIS3,TRMT10A,SEH1L,ZNF646,DPF3,SNU13,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,SON,DENND4A,SAP30BP,CLNS1A,OSBPL1A,GZF1,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,CCNB1IP1,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,PRPF31,LARS2,ZHX3,AK6,TATDN3,GTF2IRD1,PRPF39,CHD5,NDUFS7,HR,ZNF586,ENTPD5,SCAF1,COPS3,ATIC,MYC,SLC16A9,GTF3C3,CNOT4,PRPS1,TERF2,FDFT1,SCAF11,ADARB1,DDX28,EXOSC2,RREB1,PRIM2,PCCA,AOC2,POLA1,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,HIF1A,SPEN,MED15,ZBTB12,ZCCHC6,PURB,SQLE,UMPS,NCOR1,MACROD1,DHCR7,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,UROD,NDUFB5,OLA1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,PDE3A,NOP56,TERF2IP,CHD7,FLAD1,ZNF827,SLX4,PUS3,KDM2A,UCHL5,LPIN2,SSBP1,CMPK1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,DLG4,SATB2,MED16,PNN,SETD7,POLG2,HSD3B7,DHX57,SNCA,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,FTSJ1,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,LIAS,IKBKAP,NOL3,FOXO3,MAD2L2,SFR1,DCTPP1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,HARS2,UPF2,COPS7B,CELF1,EXOSC4,YBX3,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,TTLL5,APEX1,PSAT1,ADSL,APTX,KLF6,MMAA,NOP58,POLR2A,SLC23A2,ZFP62,DDX50,ZNF155,COQ9,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,ZNF76,MVK,PHF3,ATRX,KMT2E,RARS2,SLC52A3,FANCD2,RCHY1,ZNF107,PPIL1,BCOR,SLC29A1,SIRT2,SNAPC4,AHCYL2,EDC3,SMARCB1,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,POLR3B,NDUFA6,SLC27A5,YARS,OGG1,LONP1,TRIP13,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,ITPA,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,CHAF1A,TAF9B,PAF1,GEMIN5,UBTF,GATA6,HLCS,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,ABCC3,EME1,ZC3H8,COPS6,ZNF397,NOCT,DMTF1,EMSY,AK2,ZCCHC8,TAF1,PAX2,DPF2,MED13L,SMG7,NAMPT,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,NRIP1,N4BP2,POLR1E,CPSF3L,MTHFD1,HSD17B14,ZNF629,VOPP1,ZNF234,PDE4A,TSTA3,PPAT,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,ISG15,POP1,BICD1,MYBBP1A,INTS5,FDPS,RRAGA,HK2,CDKAL1,ZFP90,TBL1X,PDE9A,AGO3,ZBTB24,NR2C2AP,TCF12,ASH1L,SLC5A5,SMARCA4,PBX1,PUDP,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,HTRA2,MAML3,MCEE,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,METTL2A,GRHL3,METTL15,POU2F1,ATXN1,DKC1,PUSL1,BATF3,WARS,TPK1,RAD54B,ZC3H12A,ALAD,IKZF4,DUS3L,ADNP,HNRNPR,COPS5,ZNF557,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SULT1C2,SUPT6H,PDE4B,DBF4,PPHLN1,MED18,ATF7IP,CHCHD10,MRPS11,GART,CTNNBL1,SHMT2,ERI3,FBL,DMRT1,PKNOX1,TOP1,ARNTL2,PPP1R9B,MSX1,GPHN,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SULT4A1,SCMH1,ZNF324B,MARS,PDE2A,MEN1,ZNF407,SYMPK,TARS,RERE,ZNF221,CTIF,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1 |
| 2.723e-33 | -74.98 | nitrogen compound metabolic process | biological process | GO:0006807 | 5501 | 964 | 16441 | 2138 |
GGT1,ASCC1,THOC5,WDR74,DCP1B,AARS2,MRPL10,HLTF,CCNL2,NT5C3A,ZNF44,HMOX2,SLC6A8,NUP160,PABPC4,SKI,ZNF37A,MMP7,SREBF2,IKZF5,ZFHX3,NSRP1,ATP5G2,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,PPM1K,HMBOX1,EIF4E3,RNMT,UPP1,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,BDH2,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,PLA2G12A,BTBD9,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,EIF2S2,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,MRPL21,PRMT5,ZNF518B,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,SMARCD3,ST6GALNAC3,IMPDH2,CPT1A,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,KPNA1,GTF2A1,GSTO2,NME7,CLASRP,RPL28,EHMT2,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,BPNT1,WDR33,SRP14,SDSL,ZNF516,TRERF1,DDX18,GTF2H2C,PAFAH1B1,NPAS2,ATP6V1A,ISG20L2,NUP43,ST3GAL6,SAFB2,ZMAT2,MCM9,UBL5,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,PYCRL,WAC,ATRIP,INTS12,GSTA4,NT5C,MSH4,MTHFD2L,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,PES1,TAF2,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,PAM,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,SERINC5,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,TGFB2,RSRC1,PSMF1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,UNC13A,ZNF710,RPL22L1,SOX6,HNRNPM,DIS3L2,DDX24,POLK,LDHA,MRPS10,ZNF467,PDE3B,FOXC1,DDX49,UBC,MRPL36,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,PSAP,KDM4C,SRM,GPBP1L1,PPARGC1B,TFIP11,POLR1A,SLC25A21,CSNK2A1,COX10,BIRC2,SCAF8,HNRNPLL,AMPD3,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,PPCDC,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,MPST,SF3A1,METTL1,CHD9,ZNF124,GCNT2,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,COL4A3BP,NOL6,SUMO3,BRCA1,ODC1,ZNF91,DLST,MGST1,MLLT10,GLS,HPRT1,MSRA,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,SEPHS2,CTU2,SARS,AOC3,MCM6,FOXO1,PRSS3,HSD17B10,FAN1,LAMTOR3,SMAD7,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,PDE10A,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,ALDH18A1,GMDS,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,NR2F1,TCF7L2,PGD,PWP1,PRPF40B,ATXN7,SYNCRIP,PALB2,TBPL1,ZNF430,DTD1,HMBS,GGT7,DDX10,BCCIP,USP7,SART1,NDUFA5,MPI,ID1,SUCLG1,PAPD4,ARID2,LPCAT2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,LPCAT3,ZNF709,TNKS1BP1,PELP1,RPAIN,ZNF121,KDM1A,DENR,METTL16,CAD,ZBTB21,NRF1,DUS4L,NUP133,HIBCH,RNF2,ETF1,ZFP37,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,CPOX,NUP214,ZNF251,EIF3H,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ABHD3,ATG7,ZNF436,INTS9,PUS1,ZNF18,MED20,EIF2B3,PPIL3,MUTYH,ZNF507,DMGDH,NIFK,MCM10,AUH,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,NDUFV1,ZNF561,CWC27,HIST2H3D,SELT,DDX31,POLR1B,CD44,SNAPC5,PCSK6,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,TOP3A,DHX34,HIST1H4J,EXOG,NEU1,POLR3A,SMPDL3B,ZRANB3,POLR3G,GPC2,SRBD1,L3MBTL3,ZBTB8OS,ADAT2,TAF4,TBX3,SET,CSRNP1,MSH3,BCAS3,EIF2S1,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,GCSH,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,AARS,UBR5,LPIN1,MGA,RPS16,RNF111,ME1,CHD2,MEIS3,TRMT10A,CSGALNACT2,SEH1L,ZNF646,DPF3,SNU13,GDAP1,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,DENND4A,SON,SAP30BP,CLNS1A,GZF1,SKIL,DDAH2,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,XPNPEP1,CCNB1IP1,BMI1,SPOCK2,SPOCK3,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,PRPF31,LARS2,ZHX3,AK6,TATDN3,GTF2IRD1,SSR4,PRPF39,CHD5,NDUFS7,IGF2BP3,HR,ZNF586,ENTPD5,SCAF1,COPS3,MYC,ATIC,SLC16A9,GTF3C3,CNOT4,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,DDX28,EXOSC2,RREB1,PRIM2,PCCA,AOC2,POLA1,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZBTB12,ZCCHC6,PURB,DPEP1,UMPS,NCOR1,CNDP2,MACROD1,ZFHX2,CPT1C,HS2ST1,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,UROD,NDUFB5,OLA1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,PDE3A,NOP56,TERF2IP,CHD7,FLAD1,ZNF827,SLX4,ASNS,PUS3,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,CMPK1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,DLG4,SATB2,MED16,PNN,SETD7,POLG2,DHX57,SNCA,ZBTB25,VDR,BAZ1A,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,LARGE,H2AFX,FTSJ1,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NOSTRIN,NCOR2,UTP14A,B4GALT5,C10orf2,MRI1,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,IKBKAP,NOL3,FOXO3,MAD2L2,SFR1,DCTPP1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,PHYKPL,HARS2,UPF2,COPS7B,NLGN3,CELF1,EXOSC4,YBX3,NT5M,FAM120B,PFKFB4,TSHZ1,TTLL5,APEX1,PSAT1,ADSL,APTX,KLF6,GUF1,MMAA,NOP58,POLR2A,SLC23A2,ZFP62,DDX50,ZNF155,COQ9,HNRNPH3,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,IMMP2L,ZNF76,PHF3,EIF3C,ATRX,KMT2E,RARS2,SLC52A3,CERS5,FANCD2,RCHY1,PLOD1,ZNF107,PPIL1,BCOR,SLC29A1,SIRT2,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,PCYOX1L,SRPRB,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,HYAL1,POLR3B,NDUFA6,YARS,OGG1,LONP1,TRIP13,CARM1,SRPK2,ELOF1,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ITPA,ZNF680,MINA,HDAC8,MTHFD1L,CAV1,KMT2C,ZSCAN2,SOX4,ST3GAL5,CHAF1A,TAF9B,PAF1,GEMIN5,UBTF,GATA6,HLCS,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,EME1,ZC3H8,COPS6,ZNF397,NOCT,DMTF1,EMSY,AK2,CHST11,ZCCHC8,TAF1,PAX2,DPF2,PCSK7,MED13L,SMG7,PHGDH,NAMPT,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,GLTP,NRIP1,N4BP2,POLR1E,CPSF3L,MTHFD1,ZNF629,VOPP1,ZNF234,PDE4A,TSTA3,PPAT,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,LIG4,PSMA1,WWC1,PRDM1,EIF2A,CORIN,ISG15,POP1,BICD1,MYBBP1A,INTS5,RRAGA,HK2,CDKAL1,ZFP90,TBL1X,PDE9A,AGO3,ZBTB24,NR2C2AP,TCF12,ASH1L,SLC5A5,CEMIP,SMARCA4,PBX1,ARSJ,PUDP,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,CBR4,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,HTRA2,MAML3,TMLHE,MCEE,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,GRHL3,METTL2A,MRRF,NLN,METTL15,ATXN1,POU2F1,DKC1,PUSL1,BATF3,WARS,TPK1,RAD54B,ZC3H12A,HYAL3,ALAD,DUS3L,IKZF4,ADNP,HNRNPR,COPS5,ZNF557,ARNTL,CEBPZ,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,BCKDK,SULT1C2,SUPT6H,PDE4B,DBF4,PPHLN1,MED18,ATF7IP,CHCHD10,GFM2,MRPS11,GART,CTNNBL1,HAS3,SHMT2,ERI3,FBL,DMRT1,PKNOX1,TOP1,RPS6KB2,ARNTL2,PPP1R9B,MSX1,KDM5B,GPHN,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SULT4A1,SCMH1,ZNF324B,MARS,PDE2A,MEN1,EIF5B,ZNF407,SYMPK,TARS,RERE,ZNF221,CTIF,HSPA1B,ZNF708,SERINC1,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1,NIT1 |
| 1.442e-32 | -73.32 | nucleic acid metabolic process | biological process | GO:0090304 | 3911 | 734 | 16441 | 2138 |
ASCC1,THOC5,WDR74,DCP1B,AARS2,HLTF,CCNL2,ZNF44,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ZNF148,KDM5C,SRRM2,ZNRD1,FTSJ3,HMBOX1,RNMT,EHMT1,NFIA,RFX2,WDHD1,C5AR1,MCM2,RBM28,ZNF197,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,HERC2,TRIP6,KHDRBS1,SIRT7,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ZNF326,MED24,GEMIN4,PRMT5,ZNF518B,PABPC1,PPA1,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,TYW1,ZNF512B,USP10,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,KPNA1,GTF2A1,CLASRP,RPL28,EHMT2,CDK9,CCDC85B,ZNF160,CNOT6,WDR33,ZNF516,TRERF1,DDX18,GTF2H2C,NPAS2,ISG20L2,NUP43,SAFB2,ZMAT2,MCM9,UBL5,RPP30,BCAS2,ZSWIM7,ACD,ERI1,ZKSCAN1,WAC,ATRIP,INTS12,MSH4,TRMT12,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,MEF2D,FGFR1,PES1,TAF2,KDM4B,ELP2,NSMCE2,HIPK2,POLR3E,HOXA3,FUS,BRCC3,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,XPC,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,RSRC1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,SOX6,HNRNPM,DIS3L2,DDX24,POLK,ZNF467,FOXC1,DDX49,UBC,ANXA1,RPA1,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,BIRC2,SCAF8,HNRNPLL,SRSF2,PHF5A,COPS4,DHX33,TRMU,XRCC2,HKR1,ZNF85,RAN,POLE3,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,SUMO3,BRCA1,ZNF91,MLLT10,GLS,TCF7L1,TP53BP1,CHD3,PER1,E2F4,RAD51B,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,MCM6,FOXO1,HSD17B10,LAMTOR3,SMAD7,FAN1,HES6,BARX2,ZFP36L1,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,NT5E,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,TCF7L2,NR2F1,PWP1,PRPF40B,ATXN7,PALB2,SYNCRIP,TBPL1,ZNF430,DTD1,DDX10,BCCIP,USP7,SART1,ID1,PAPD4,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,ZNF709,TNKS1BP1,PELP1,ZNF121,RPAIN,KDM1A,METTL16,NRF1,ZBTB21,DUS4L,NUP133,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,CTC1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,NUP214,ZNF251,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,INTS9,PUS1,MED20,ZNF18,PPIL3,MUTYH,ZNF507,NIFK,MCM10,RFX1,AGO2,VARS,FOXP1,RMI1,ZNF594,ZNF561,CWC27,HIST2H3D,DDX31,POLR1B,SNAPC5,TRNP1,GINS3,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,TOP3A,HIST1H4J,EXOG,POLR3A,ZRANB3,POLR3G,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,POLB,CUL4A,PRKAB2,DDX19A,PLRG1,GABPB2,AARS,UBR5,LPIN1,MGA,RPS16,RNF111,CHD2,MEIS3,TRMT10A,SEH1L,ZNF646,DPF3,SNU13,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,SON,DENND4A,SAP30BP,CLNS1A,GZF1,SKIL,TRRAP,CCNT1,NSMCE1,LUC7L3,ZNF81,HIC2,CCNB1IP1,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,LARS2,ZHX3,PRPF31,TATDN3,GTF2IRD1,PRPF39,CHD5,HR,ZNF586,SCAF1,COPS3,MYC,GTF3C3,CNOT4,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,ZNF425,ASCC3,EPRS,ALKBH3,HIF1A,SPEN,MED15,ZBTB12,ZCCHC6,PURB,NCOR1,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,NOP56,TERF2IP,CHD7,ZNF827,SLX4,PUS3,KDM2A,UCHL5,LPIN2,SSBP1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,BRD4,RFC3,SATB2,MED16,PNN,SETD7,POLG2,DHX57,ZBTB25,VDR,BAZ1A,DNTTIP1,MSX2,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,H2AFX,ALKBH1,TRMT2A,PDCD11,NOLC1,XRCC4,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,HARS2,COPS7B,UPF2,CELF1,EXOSC4,YBX3,NT5M,FAM120B,TSHZ1,TTLL5,APEX1,APTX,KLF6,NOP58,POLR2A,ZFP62,DDX50,ZNF155,HNRNPH3,ORC5,ATM,DDIT3,KAT6A,ZNF76,PHF3,ATRX,KMT2E,RARS2,FANCD2,RCHY1,ZNF107,PPIL1,BCOR,SIRT2,SNAPC4,EDC3,SMARCB1,YLPM1,JAZF1,RELB,GPATCH1,ZEB1,POLR3B,YARS,OGG1,LONP1,TRIP13,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,CHAF1A,TAF9B,GEMIN5,UBTF,PAF1,GATA6,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,EME1,COPS6,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,ZCCHC8,PAX2,DPF2,MED13L,SMG7,DDIT4,CEP164,ELL,ZNF354A,ATXN2,BANF1,BUD31,NRIP1,POLR1E,N4BP2,CPSF3L,ZNF629,VOPP1,ZNF234,TRA2A,JMJD1C,ELP3,WBSCR22,ZFP14,WWC1,LIG4,PRDM1,ISG15,POP1,BICD1,MYBBP1A,INTS5,RRAGA,CDKAL1,ZFP90,TBL1X,AGO3,NR2C2AP,ZBTB24,TCF12,ASH1L,SMARCA4,PBX1,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,BRE,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,MAML3,NARS2,PRAME,PTBP2,TFCP2,PARP2,SFSWAP,METTL2A,GRHL3,METTL15,POU2F1,ATXN1,DKC1,PUSL1,BATF3,WARS,RAD54B,ZC3H12A,IKZF4,DUS3L,ADNP,HNRNPR,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SUPT6H,DBF4,PPHLN1,ATF7IP,MED18,MRPS11,CTNNBL1,ERI3,FBL,DMRT1,PKNOX1,TOP1,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MARS,MEN1,ZNF407,SYMPK,TARS,CTIF,ZNF221,RERE,ZNF708,GADD45A,ZRANB2,NCBP2,POLR1C,NFKBIB,TATDN1 |
| 1.598e-31 | -70.91 | NTRK1 (neurotrophic tyrosine kinase, receptor, type 1) | protein interactions | 4914 | 1951 | 455 | 16036 | 2270 |
PRDX6,PRKCSH,DDX19A,PLRG1,AARS2,NAT10,SBF2,ENAH,HLTF,PRKCA,NUP160,AARS,PABPC4,LPIN1,EXOC1,AP1M1,PDS5B,MAD1L1,VPS52,SRRM2,CDK6,FTSJ3,GDAP1,RNMT,LIMA1,GNL3,EXOC6B,TCEB3,CUX1,KIF15,WDHD1,CAMSAP2,HIST1H2BL,MCM2,RBM28,SAP30BP,CLNS1A,STOML2,PYCR1,DDX3X,LSM14A,CCNT1,LUC7L3,LRRC40,XPNPEP1,RIOK1,FIP1L1,ZNF598,CARS,EPM2AIP1,JUP,PRPF31,LARS2,ANKRD17,KHDRBS1,SLK,TRIO,PIK3R4,CCDC47,CLINT1,CDC73,IGF2BP3,DDX56,EIF2S2,UBE3A,ASAP1,MCM5,COPS3,ATIC,MYC,TNPO3,GTF3C3,ANP32B,NOC3L,GEMIN4,PRMT5,LPCAT1,AGL,PRPS1,FMNL2,PABPC1,PPA1,SERBP1,NOM1,GATAD2B,DDX28,PRIM2,POLA1,EPS15L1,PTPN12,USP10,MAP7D1,IMPDH2,NELFA,CPT1A,ABCF1,MTR,ARIH2,PHF6,RDH11,SEC31A,CAT,IRS1,DYNC1H1,ASCC3,EPRS,TSR1,KPNA1,KIDINS220,NSF,TRAP1,LEMD3,SRP68,SENP3,C7orf50,KIAA0196,PDLIM5,SGSM3,COG5,DDX18,ATP6V1A,PAFAH1B1,ACTR3,DDR2,OLA1,MYH9,AP1B1,STAM,HSPA1A,HNRNPA3,DECR1,ASNS,SHC1,ZKSCAN1,PPID,UCHL5,VGF,MRPS27,SERPINH1,NAA35,RFC4,PMS1,MPP6,GARS,RFC3,EIF3J,PCMT1,ATP6V0A1,LRRC8A,GNL1,PNN,MED16,DSP,TTC28,FKBP3,DHX57,MAT2A,PES1,SMARCC1,ELP2,G6PD,DNAJA3,WDR7,SLC4A7,FUS,ANXA2,PDCD11,TROVE2,CEP170,VWA8,LRCH1,MORC2,SCAMP3,TTC27,MRI1,SF3A3,KIF5C,RTN4,ATG2B,MON2,MLH1,OPA1,IKBKAP,RSRC1,GIGYF2,NEDD4,ABL1,SNW1,LTN1,ANXA5,RDX,UPF2,EXOSC4,LARP4B,HNRNPM,NUDC,DIS3L2,SPTAN1,FAM98A,PSAT1,APEX1,DDX24,ZC3H18,LDHA,TBRG4,ADSL,PACS1,PTK2,PPIP5K2,NOP58,UBC,POLR2A,ECH1,RPA1,OXSR1,KLHL22,RARS,PXDN,HNRNPH3,PGAM5,RABEP1,GPATCH4,IPO4,LRRC41,SRM,LETM1,EIF3C,TFIP11,RARS2,HECTD3,FANCD2,CSNK2A1,PLOD1,TTI1,TMEM132A,SEC16A,HNRNPLL,SCAF8,EDC3,ABL2,SRPRB,ANAPC1,RAP1A,SRSF2,COPS4,THADA,UBAP2L,RAN,POLR3B,YARS,LONP1,TRIP13,CARM1,PRKACB,SRPK2,SF3A1,CDC37,TMPO,DBN1,TNK2,FMNL3,SLC3A2,MIOS,TXLNG,SKIV2L2,HARS,CDK4,ANK2,HSPA5,MARCKSL1,CAV1,PITPNB,MTHFD1L,KCNH2,LSG1,TIMM44,YTHDF2,GEMIN5,PAF1,UBTF,LSS,PRPF4,COPS6,RNF214,C2CD5,USP15,SARS,TTN,MCM6,AK2,ZCCHC8,SEC24D,VTA1,MEX3A,HSD17B10,MAPK8IP3,XPO7,PHGDH,ETFB,NAMPT,RNF40,P3H1,ATXN2,PPIL2,TIMELESS,CTR9,VAPB,CCDC124,ALDH18A1,CWF19L2,NIPSNAP1,MTHFD1,ZNF629,MSI2,RANBP6,TRAPPC9,PPAT,TLE3,TRA2A,XPO5,HAUS6,ELP3,PSMA1,RNH1,EIF2A,SUPT5H,SYT1,VAC14,EXOC6,POP1,BICD1,SPAG9,MYBBP1A,UBAP2,SYNCRIP,FSCN1,INTS5,FDPS,EXOC4,HK2,SLC16A1,SH3PXD2A,DDX10,BCCIP,TCF12,USP7,SNX27,SART1,LPCAT2,RBFOX2,OSBPL9,PPP2R2A,SMARCA4,RSL1D1,TNKS1BP1,PIBF1,PELP1,GBF1,KDM1A,METTL16,CAD,VPS18,FARSA,ANKRD13A,NUP133,UBR1,DNAJB6,PPFIBP1,CPSF3,VCL,PRMT3,AUP1,IPO11,PRPF19,SKIV2L,SEC24A,KDM3B,WDR36,ARHGAP17,TUBA1A,DDX41,AKAP8L,NARS,SFSWAP,VIM,DKC1,NUP214,EIF3H,PUM3,WARS,IFT81,KPNA3,HNRNPR,ADNP,COPS5,CEBPZ,ATG7,SLC25A11,FKBP5,HEATR1,USP11,TMEM33,DNAJC2,MCM10,AGO2,KLC4,PDE4B,VPS45,MAP1S,WDR26,VARS,SOGA1,CSNK1A1,BZW2,GART,SEC24C,DCTN4,SHMT2,DDX31,POLR1B,PCK2,FBL,HSD17B12,SLC25A1,TOP1,GPHN,PSPC1,SMARCAD1,ABCF2,TPM4,TOP3A,FERMT2,RAP1GDS1,RANGAP1,ARHGEF12,MARS,ARHGAP32,PALLD,EIF5B,RHOT2,SYMPK,PIK3CB,TARS,POLR3A,MFN2,SRBD1,WDR35,SET,CUL2,MSH3,GLG1,EIF2S1,RBM26,POLR1C,TRAPPC12 |
| 2.683e-31 | -70.39 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | 1705 | 383 | 17758 | 2279 |
ZNF292,POLB,TMEM109,SBF2,NUP160,UBR5,MGA,AMBRA1,TOM1L1,SKI,C1orf159,SREBF2,ZFHX3,ATP5G2,RABGAP1L,RNF111,SUCLG2,ZNF148,FXN,ZNRD1,SEH1L,HMBOX1,NRAS,LIMA1,C2orf76,AKAP12,MCM2,SON,STOML2,SPOP,DDX3X,BRCA2,RAD18,SH3RF1,NSMCE1,ARL6IP5,RUNX1,FAM118A,LPP,WDR75,PRPF38B,PRPF31,ANKRD17,KHDRBS1,SLK,TRIO,OPHN1,GTF2IRD1,PRPF39,PARN,CDC73,NDUFS7,SLC39A11,EIF2S2,UBE3A,TSPAN2,ASAP1,INTS7,MYC,TNPO3,ANP32B,CNOT4,LPCAT1,COQ3,CAV2,FDFT1,MYB,SCAF11,USE1,FADS1,GATAD2B,EXOSC2,STAG1,PRIM2,RREB1,MYO10,POLA1,PCCA,EIF4A2,PTPN12,TTYH2,CAT,MTHFD2,KPNA1,HIF1A,SPEN,ZBTB12,D2HGDH,SQLE,CNOT6,BPNT1,NCOR1,WDR33,DHCR7,RTTN,PPDPF,PTCD2,SPRED2,BIRC6,PAFAH1B1,DDR2,OLA1,VTI1A,FOSL2,LCLAT1,EEA1,NOP56,CHD7,PRKD3,PUS3,WAC,SOCS6,DTNBP1,NBEA,C16orf58,TTC3,NT5C,SSBP1,DENND1A,LYST,ZCCHC14,MPP6,BRD4,PDK1,SFXN4,ARHGEF10,ATP6V0A1,GNL1,PNN,MED16,TTC28,ERC1,FGFR1,HSD3B7,ZFAND3,ARHGAP21,CAMK2D,KDM4B,ELP2,NSMCE2,HIPK2,LARGE,MDN1,BRCC3,NOLC1,XRCC4,MAPT,HMGA2,INSIG2,BRAF,TCF3,TRAK1,ZNF280C,FARS2,MYNN,TGFB2,RSRC1,MAD2L2,NEDD4,SFR1,DCTPP1,KRI1,TADA3,PSMG4,NISCH,RDX,RPL22L1,SOX6,SPTAN1,APEX1,CLYBL,WDFY3,TMEM126A,TBRG4,ZNF467,UBE2K,KLF6,NOP58,FOXC1,SLC23A2,TRIB3,TOE1,FBXO21,BAZ2B,POLE2,RNF138,SVIL,ATM,GPAM,ADK,ANAPC4,CYP24A1,PHF3,MVK,TRIM16,ATRX,NF1,POLR1A,PPARGC1B,PTPRA,CSNK2A1,SCAF8,FRRS1,SMARCB1,DST,SRPRB,ANAPC1,SRSF2,PHKA1,ANAPC11,UBAP2L,IPP,OGG1,TRIP13,CARM1,PRKACB,SRPK2,PTPRK,TMPO,DBN1,METTL1,ATF4,MIOS,CDK4,GDPD1,TMEM216,GMFB,COL4A3BP,PSMG1,MARCKSL1,CAV1,PITPNB,KRTCAP2,SERGEF,ST3GAL5,CRYBG3,MLLT10,TIMM44,CXADR,RHOU,MSRA,EPN2,LSS,RAD51B,PQBP1,PPP3CC,MAGI1,DCAF5,RNF214,TNRC6A,OXNAD1,AOC3,STX8,ZCCHC8,SEC24D,NKD2,XPO7,TIMM10,LYRM2,RHBDD1,RNF141,MBD2,ATXN2,VPS72,TIMELESS,ALDH18A1,NRIP1,NT5E,CRADD,LAMC1,PPAT,ELOVL6,ELP3,HOMER2,BCS1L,METTL22,CYB5B,AGAP1,TCF7L2,EXOC6,ATXN7,BICD1,MYBBP1A,SYNCRIP,FDPS,EXOC4,CDKAL1,PTRH2,SIL1,ZFP90,HMBS,TBL1X,DDX10,NR2C2AP,TCF12,BCCIP,ZNF706,ASH1L,FEZ2,PAPD4,RBFOX2,OSBPL9,PBX1,RIPK1,ST7L,SPATS2,NRF1,MPHOSPH10,BRE,LYPLAL1,CCDC50,NUP133,UBR1,ZDHHC6,C15orf40,IKBKB,ZNF142,ETF1,HIBCH,GNG5,IPO11,TMLHE,TLCD1,PHLDB2,PTBP2,TUBA1A,COL5A2,PARP2,R3HDM1,POU2F1,MRRF,ENC1,USP36,TMEM186,TPK1,KPNA3,HNRNPR,ADNP,DUSP19,HSPB8,RNF130,ZNF18,HEATR1,MUTYH,TSPAN5,PARD3,KLHL24,BCKDK,DYM,DBF4,LETMD1,IGF2BP2,FOXP1,PEX7,GART,TMEM161A,DSG2,DCTN4,POLR1B,PCK2,ERI3,CD44,GPHN,SMARCAD1,RAP1GDS1,FERMT2,ARHGEF12,EIF5B,PEAK1,RHOT2,TMEM175,TARS,POLR3A,POLR3G,TPD52L2,DAGLB,ADAT2,CUL2,MSH3,GLG1,RBM26,KIF1B,GCSH |
| 8.853e-31 | -69.20 | cellular metabolic process | biological process | GO:0044237 | 8503 | 1352 | 16441 | 2138 |
PTP4A1,GGT1,THOC5,DPH1,DCP1B,AARS2,MRPL10,CCNL2,ZNF44,HMOX2,SLC6A8,ABHD6,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,ATP5G2,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,UPP1,EHMT1,NFIA,WDHD1,C5AR1,MCM2,ZNF197,PYCR1,SSU72,RAD18,BDH2,MPV17,RIOK1,RUNX1,ZNF532,BANP,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,RBM20,UBE3A,DHX37,APLF,MED24,GEMIN4,MRPL21,PABPC1,PPA1,MYB,ZNF675,GATAD2B,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,ST6GALNAC3,SNAP25,TRIM37,SRA1,USP46,RDH11,IRS1,KPNA1,GSTO2,NME7,RPL28,EHMT2,CCDC85B,BPNT1,SRP14,C18orf25,SDSL,GTF2H2C,PAFAH1B1,DDR2,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,ZSWIM7,ACD,WAC,INTS12,MSH4,PXK,MGLL,TRMT12,ZC3H3,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,KCNH3,MEF2D,SLC35D1,DSP,NUDT15,MAT2A,FBXL5,KDM4B,ELP2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,MORC2,COMMD10,HMGA2,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,TAF3,UNC13A,ACOT11,LTN1,PTGS1,ZNF710,FBXL19,RPL22L1,SPTAN1,VPS37A,DDX24,USP42,LDHA,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,MTMR1,CYP24A1,CUL7,TRIM16,SLC25A21,SCAF8,HNRNPLL,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,HKR1,TRIML2,ZNF3,ZMYM2,RBCK1,AEBP2,ATF4,PPARG,CDK4,HSPA5,TSN,SUMO3,KCNH2,ODC1,DLST,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,CHD3,E2F4,PPP3CC,PRPF4,TSEN2,BEND6,USP15,CTU2,FOXO1,CLK1,PRSS3,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,VAPB,CTR9,ICE2,PNPLA3,LRSAM1,WARS2,USP49,SETD2,OBSCN,ACOXL,TCF7L2,PRPF40B,CASS4,DTD1,GGT7,PTP4A2,DDX10,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,SUCLG1,PAPD4,ARID2,NDUFAF2,NTSR1,SLC2A1,RPS29,LAGE3,RIPK1,DENND3,TNKS1BP1,ZNF121,FDX1,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,AHCYL1,SPIDR,PRPF19,KDM3B,RAB7A,CA5B,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,ZNF507,DMGDH,NIFK,ESCO1,MINK1,MCM10,AUH,RFX1,AGO2,APRT,VARS,FOXP1,SLC25A20,ADH5,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,TOP3A,EXOG,POLR3A,SMPDL3B,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,SUCLG2,DPH6,CHD2,CSGALNACT2,ZNF646,ACADS,GDAP1,ZDHHC14,SON,DENND4A,CLNS1A,SPOP,DOT1L,GZF1,DDAH2,TRRAP,CCNT1,SH3RF1,NSMCE1,LUC7L3,HIC2,XPNPEP1,BLMH,BMI1,SPOCK2,SPOCK3,PRPF38B,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,NDUFS7,HR,USPL1,SCAF1,MYC,PIGG,CNOT4,FDFT1,EXOSC2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAPGEF4,ARID1A,NELFA,MTR,ZNF850,ANGPTL4,PHF6,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,SMYD3,CPT1C,HS2ST1,ZNF254,BIRC6,UROD,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,NOP56,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,PREX1,PCMT1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,TRAF3,SETD6,XRCC4,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,RPS6KA5,INPP1,GIGYF2,SFR1,ABL1,ELP5,CELF1,CLK2,PXN,TTLL5,APEX1,PSAT1,AGPAT4,ADSL,GUF1,KLF6,SLC23A2,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,ATM,NDUFS5,ADK,DDIT3,KAT6A,IMMP2L,ZNF76,PIGM,EIF3C,KMT2E,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,KANSL1,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,SLC35C2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,FBXW4,ZNF195,SIRT6,ITPA,MINA,KSR2,MTHFD1L,PITPNB,SGK2,KMT2C,ST3GAL5,MPC1,TIMM44,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,EME1,ZC3H8,DCAF5,FBXO45,ZCCHC8,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,RNF141,ELL,P3H1,ZNF354A,ISPD,ATP6V0D1,MTHFD1,ZNF629,ZNF234,PPAT,ELOVL6,TRA2A,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,CORIN,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,TBCK,PDE9A,AGO3,NR2C2AP,TCF12,DLL4,TNXB,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,CBR4,FHIT,ADCK4,UTP4,GNG5,AUP1,MAML3,NARS2,PRAME,METTL2A,GRHL3,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,ALAD,DUS3L,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,PDE4B,MED18,ATF7IP,CHCHD10,PIP4K2A,GFM2,PEX7,SEC24C,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,SULT4A1,SCMH1,ZNF324B,PDE2A,PEAK1,EIF5B,ZNF221,CTIF,SERINC1,DAGLB,GADD45A,AGTPBP1,POLR1C,NFKBIB,GNB3,ASCC1,WDR74,CACNA1H,HLTF,NT5C3A,NUP160,SYNJ1,PABPC4,TOM1L1,SREBF2,NEK6,PMAIP1,NSRP1,FAAH2,FNIP2,ZNF148,FXN,CDK6,PTPRM,RFX2,MSRB3,DCUN1D5,RBM28,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIP1L1,RBP1,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,SLK,SIRT7,PLA2G12A,RSF1,YARS2,ABCA7,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,PRMT5,ZNF518B,COQ3,AGL,MAP3K12,HMGCR,FADS1,PEA15,BDNF,GTF2H3,TIMM8B,RB1CC1,PRDM16,EIF4A2,ZNF512B,SMARCD3,IMPDH2,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,ZNF783,CLASRP,GTF2A1,CDK9,SURF1,ZNF160,CNOT6,SENP3,WDR33,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,ATP6V1A,NPAS2,PDK4,TUBB6,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ZKSCAN1,ERI1,PYCRL,ATRIP,GSTA4,NT5C,MTHFD2L,LSM10,GARS,STAMBP,NPM3,ATF7IP2,ATP6V0A1,FKBP3,FGFR1,PDE8B,PES1,TAF2,GNG2,CDC16,HIPK2,PEMT,PAM,FUS,BRCC3,ZBTB11,YEATS2,TRIM36,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,TADA3,NPRL2,SUV39H2,GATC,SOX6,HNRNPM,LYPLA2,DIS3L2,FGF9,POLK,MRPS10,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,RPA1,TRIB3,RARS,ETFDH,TOE1,BAZ2B,PXDN,POLE2,PLPPR2,STX1A,ARID3B,PTPN4,PSAP,GPAM,ANAPC4,KDM4C,SRM,GPBP1L1,PPARGC1B,POLR1A,TFIP11,MFGE8,HECTD3,CSNK2A1,RNF43,COX10,SEC16A,BIRC2,ABL2,DHX33,PHKA1,TRMU,XRCC2,PPCDC,POLE3,RAN,ZNF85,ETV1,MPST,PTPRK,SF3A1,METTL1,CHD9,GCNT2,ZNF124,SKIV2L2,ZNF414,BAZ2A,HARS,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,ZNF91,MGST1,KIF16B,GLS,MSRA,TP53BP1,PER1,EEFSEC,SOCS4,RAD51B,TNFRSF1A,DLX2,CHMP4C,SEPHS2,XYLB,AOC3,TTN,SARS,MCM6,HSD17B10,HES6,ZFP36L1,BARX2,RLF,RNF40,TRMT13,PDE10A,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,CAMKK2,TRAPPC9,PAXBP1,TLE3,UTP15,RNH1,MEX3B,TRAPPC6B,SUPT5H,NR2F1,VAC14,PGD,PWP1,ATXN7,FAM135A,SPAG9,SYNCRIP,PALB2,IRAK2,TBPL1,ZNF430,HMBS,BRSK2,NAPA,PRKAR2A,RNF114,NDUFA5,CYLD,RBFOX2,LPCAT2,PPP2R2A,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,ZBTB21,DUS4L,UBR1,ZDHHC6,IKBKB,RNF2,ETF1,ZFP37,HIBCH,PRMT3,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,NARS,CPOX,AKAP13,ENC1,NUP214,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ABHD3,ZNF436,PUS1,ZNF18,PPIL3,MAP3K13,CSNK1A1,RMI1,ZNF594,PTPN2,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,SELT,FBXO31,HSD17B12,GINS3,ZNF654,ZMYM5,DHX34,TEX14,HIST1H4J,PIK3CB,NEU1,ZRANB3,POLR3G,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,NDUFAF5,MYRF,RPS6KC1,GCSH,MYCBP2,POLB,PRDX6,TNFRSF21,PRKAB2,DDX19A,PLRG1,AARS,UBR5,MGA,GIPR,RPS16,RNF111,ME1,TRMT10A,MEIS3,FUT11,SEH1L,SNU13,DPF3,SETD1B,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,CUX1,TCEB3,SAP30BP,SKIL,ZNF81,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,EGR1,ZHX3,AK6,PID1,GTF2IRD1,CCDC47,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,PI4KB,ENTPD5,ZNF586,COPS3,ATIC,SLC16A9,GTF3C3,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,SIK3,DDX28,SYNGAP1,AOC2,POLA1,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,NSF,UBAP1,D2HGDH,ZBTB12,RIOK3,PURB,UMPS,PEX13,MACROD1,MAP2K4,ZFHX2,PTCD2,LIN28B,ZBTB37,HFM1,NDUFB5,OLA1,KLHL18,FOSL2,PDE3A,PHC2,TERF2IP,FLAD1,CHD7,ZNF827,PUS3,KDM2A,SHC1,UCHL5,VGF,SSBP1,KMT2A,RFC4,RFC3,PDK1,MTIF2,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,VDR,TAMM41,DNAJA3,ZNF236,H2AFX,ACP1,TRMT2A,ALKBH1,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,LIAS,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,NEDD4,ZNF239,ZNF483,DCTPP1,COMMD9,PTRF,PMPCA,PHYKPL,COPS7B,UPF2,HARS2,NLGN3,EXOSC4,YBX3,MAP3K14,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,TBRG4,APTX,PTK2,NOP58,MMAA,POLR2A,ECH1,YIF1A,FBXO21,KLHL22,ZDHHC11,HNRNPH3,RNF138,PGAM5,LRRC41,STK4,PHF3,MVK,FEM1C,NF1,PTPRA,CERS5,FANCD2,TRPM6,RCHY1,ZNF107,PLOD1,BCOR,SIRT2,SLC29A1,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,MRPS30,SRPRB,ANAPC1,RAP1A,YLPM1,ATG3,ANAPC10,HYAL1,IPP,RELB,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,PRKACB,TRIP13,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,TAF9B,CHAF1A,UBTF,GEMIN5,PAF1,UBE3D,GATA6,TRMT5,MKL2,PQBP1,ABCC3,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,PIGN,CHST11,AK2,FN1,TAF1,SEC24D,PAX2,GPAT3,DPF2,ALG8,MED13L,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,ATXN2,BANF1,BUD31,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,ISG15,MYBBP1A,INTS5,HK2,EXOC4,RRAGA,ZFP90,PDSS2,ZBTB24,ASH1L,SLC5A5,CSTA,PUDP,GBF1,ZSCAN5A,FARSA,BRE,LYPLAL1,CAMTA2,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,TMLHE,MCEE,ACSL5,PTBP2,TFCP2,PARP2,SFSWAP,NLN,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,ADNP,COPS5,SRFBP1,HEATR1,USP11,KLHL24,TNIK,SULT1C2,SH2D3A,DBF4,TKFC,PPHLN1,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,HAS3,KDELC1,SHMT2,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,HSPA1B,RERE,ZNF708,ALG5,CUL2,ZRANB2,NCBP2,TATDN1,ZAK |
| 4.262e-29 | -65.33 | primary metabolic process | biological process | GO:0044238 | 8686 | 1368 | 16441 | 2138 |
PTP4A1,GGT1,ADAM19,THOC5,DPH1,DCP1B,AARS2,MRPL10,CCNL2,ZNF44,SLC6A8,ABHD6,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,ATP5G2,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,UPP1,EHMT1,NFIA,WDHD1,C5AR1,MCM2,ZNF197,PYCR1,SSU72,RAD18,BDH2,RIOK1,RUNX1,ZNF532,BANP,TRIO,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,GEMIN4,MRPL21,PABPC1,PPA1,MYB,ZNF675,GATAD2B,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,ST6GALNAC3,TRIM37,SRA1,USP46,RDH11,IRS1,KPNA1,GSTO2,NME7,RPL28,EHMT2,CCDC85B,BPNT1,SRP14,C18orf25,GALE,SDSL,GTF2H2C,PAFAH1B1,DDR2,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,ZSWIM7,ACD,WAC,MMP14,INTS12,MSH4,PXK,MGLL,TRMT12,ZC3H3,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,KCNH3,MEF2D,SLC35D1,DSP,NUDT15,MAT2A,FBXL5,KDM4B,ELP2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,MORC2,COMMD10,HMGA2,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,TAF3,ACOT11,LTN1,PTGS1,ZNF710,FBXL19,RPL22L1,SPTAN1,VPS37A,DDX24,USP42,LDHA,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,MTMR1,CYP24A1,CUL7,TRIM16,SLC25A21,SCAF8,HNRNPLL,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,HKR1,TRIML2,ZNF3,ZMYM2,RBCK1,AEBP2,ATF4,PPARG,CDK4,HSPA5,TSN,SUMO3,KCNH2,ODC1,DLST,MLLT10,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,E2F4,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,BEND6,USP15,CTU2,FOXO1,CLK1,PRSS3,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,VAPB,CTR9,ICE2,PNPLA3,LRSAM1,WARS2,USP49,SETD2,OBSCN,ACOXL,TCF7L2,PRPF40B,CASS4,DTD1,GGT7,PTP4A2,DDX10,BCCIP,USP7,SART1,MPI,ID1,SUCLG1,PAPD4,ARID2,SLC2A1,RPS29,LAGE3,RIPK1,DENND3,TNKS1BP1,ZNF121,FDX1,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,AHCYL1,SPIDR,PRPF19,KDM3B,RAB7A,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,ZNF507,DMGDH,NIFK,ESCO1,MINK1,MCM10,HM13,AUH,RFX1,AGO2,APRT,VARS,FOXP1,SLC25A20,ADH5,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,TOP3A,EXOG,POLR3A,SMPDL3B,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,SUCLG2,DPH6,CHD2,CSGALNACT2,ZNF646,ACADS,ZDHHC14,SON,DENND4A,CLNS1A,PLCXD2,SPOP,OSBPL1A,DOT1L,GZF1,DDAH2,TRRAP,CCNT1,SH3RF1,NSMCE1,LUC7L3,CFD,HIC2,XPNPEP1,BLMH,BMI1,SPOCK2,SPOCK3,PRPF38B,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,NDUFS7,HR,USPL1,SCAF1,MYC,PIGG,CNOT4,FDFT1,EXOSC2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,ARID1A,NELFA,TPRA1,MTR,ZNF850,ANGPTL4,PHF6,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,ZNF254,BIRC6,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,NOP56,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,PCMT1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,TRAF3,SETD6,XRCC4,SSH2,BRAF,B4GALT5,FARS2,RPS6KA5,INPP1,GIGYF2,SFR1,ABL1,ELP5,CELF1,DYNC2H1,CLK2,PXN,TTLL5,APEX1,PSAT1,AGPAT4,ADSL,GUF1,KLF6,SLC23A2,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,ATM,NDUFS5,APAF1,ADK,DDIT3,KAT6A,IMMP2L,ZNF76,PIGM,EIF3C,KMT2E,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,KANSL1,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,SLC35C2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,FBXW4,ZNF195,SIRT6,ITPA,TFPI,MINA,KSR2,MTHFD1L,PITPNB,SGK2,KMT2C,ST3GAL5,TIMM44,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,ZCCHC8,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,RNF141,ELL,P3H1,ZNF354A,ISPD,TENM3,ATP6V0D1,MTHFD1,HSD17B14,ZNF629,ZNF234,PPAT,ELOVL6,TRA2A,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,CORIN,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,TBCK,PDE9A,AGO3,NR2C2AP,TCF12,DLL4,CEMIP,TNXB,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,CBR4,FHIT,ADCK4,UTP4,AUP1,MAML3,NARS2,PRAME,METTL2A,GRHL3,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,DUS3L,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,PDE4B,MED18,ATF7IP,CHCHD10,PIP4K2A,GFM2,PEX7,SEC24C,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,SULT4A1,SCMH1,ZNF324B,PDE2A,PEAK1,EIF5B,ZNF221,CTIF,SERINC1,DAGLB,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,ASCC1,WDR74,CACNA1H,HLTF,NT5C3A,NUP160,SYNJ1,PABPC4,TOM1L1,SREBF2,NEK6,PMAIP1,NSRP1,FAAH2,FNIP2,ZNF148,FXN,CDK6,PTPRM,RFX2,MSRB3,DCUN1D5,RBM28,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIP1L1,RBP1,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,SLK,SIRT7,PLA2G12A,RSF1,YARS2,ABCA7,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,PRMT5,ZNF518B,COQ3,AGL,MAP3K12,HMGCR,FADS1,PEA15,BDNF,GTF2H3,TIMM8B,RB1CC1,PRDM16,EIF4A2,ZNF512B,SMARCD3,IMPDH2,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,ZNF783,TASP1,CLASRP,GTF2A1,CDK9,SURF1,ZNF160,CNOT6,SENP3,WDR33,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,NPAS2,ATP6V1A,PDK4,MYH9,TUBB6,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ZKSCAN1,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,LSM10,PERP,GARS,STAMBP,NPM3,ATF7IP2,ADAM32,ATP6V0A1,FKBP3,FGFR1,PDE8B,PES1,TAF2,CDC16,HIPK2,PEMT,FUS,BRCC3,ZBTB11,YEATS2,TRIM36,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,TADA3,NPRL2,SUV39H2,GATC,SOX6,HNRNPM,LYPLA2,DIS3L2,DDHD1,FGF9,POLK,MRPS10,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,RPA1,TRIB3,RARS,ETFDH,TOE1,BAZ2B,POLE2,STX1A,ARID3B,PTPN4,PSAP,GPAM,ANAPC4,KDM4C,GPBP1L1,PPARGC1B,POLR1A,TFIP11,MFGE8,HECTD3,CSNK2A1,RNF43,COX10,SEC16A,BIRC2,ABL2,DHX33,PHKA1,TRMU,XRCC2,PPCDC,POLE3,RAN,ZNF85,ETV1,MPST,PTPRK,SF3A1,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,SKIV2L2,ZNF414,BAZ2A,HARS,GDPD1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,ZNF91,GLS,MSRA,TP53BP1,PER1,EEFSEC,SOCS4,RAD51B,TNFRSF1A,DLX2,CHMP4C,SEPHS2,XYLB,TTN,SARS,MCM6,PGPEP1,HSD17B10,HES6,ZFP36L1,BARX2,RLF,RNF40,TRMT13,PDE10A,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,CAMKK2,TRAPPC9,CRADD,PAXBP1,TLE3,UTP15,RNH1,MEX3B,TRAPPC6B,SUPT5H,NR2F1,VAC14,PGD,PWP1,ATXN7,FAM135A,SPAG9,SYNCRIP,PALB2,IRAK2,TBPL1,ZNF430,HMBS,BRSK2,NAPA,TESC,RNF114,NDUFA5,CYLD,LPCAT2,RBFOX2,PPP2R2A,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,ZBTB21,DUS4L,UBR1,ZDHHC6,IKBKB,RNF2,ETF1,ZFP37,HIBCH,PRMT3,CASP10,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,NARS,THSD4,AKAP13,ENC1,NUP214,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ABHD3,ZNF436,PUS1,ZNF18,PPIL3,MAP3K13,CSNK1A1,RMI1,ZNF594,PTPN2,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,SELT,FBXO31,CD44,PCK2,HSD17B12,ADAMTSL3,GINS3,ZNF654,ZMYM5,DHX34,TEX14,HIST1H4J,PIK3CB,NEU1,ZRANB3,POLR3G,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,MYRF,RPS6KC1,GCSH,POLB,MYCBP2,PRDX6,TNFRSF21,PRKAB2,DDX19A,PLRG1,ADAMTS6,AARS,UBR5,MGA,RPS16,RNF111,ME1,TRMT10A,MEIS3,FUT11,SEH1L,SNU13,DPF3,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,DESI1,SAP30BP,SKIL,ZNF81,CCNB1IP1,PTPN14,WDR75,IFT57,DROSHA,EGR1,ZHX3,AK6,GTF2IRD1,CCDC47,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,PI4KB,ENTPD5,ZNF586,COPS3,ATIC,GTF3C3,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,POLA1,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,NSF,UBAP1,D2HGDH,ZBTB12,RIOK3,PURB,UMPS,PEX13,MACROD1,MAP2K4,ZFHX2,PTCD2,LIN28B,ZBTB37,HFM1,NDUFB5,OLA1,KLHL18,FOSL2,PDE3A,PHC2,TERF2IP,FLAD1,CHD7,ZNF827,PUS3,KDM2A,SHC1,UCHL5,SSBP1,PNPLA4,SERPINH1,KMT2A,RFC4,RFC3,PDK1,MTIF2,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,TAMM41,VDR,DNAJA3,ZNF236,H2AFX,ACP1,TRMT2A,ALKBH1,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,LIAS,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,NEDD4,ZNF239,ZNF483,DCTPP1,COMMD9,PTRF,NISCH,PMPCA,PHYKPL,COPS7B,UPF2,HARS2,EXOSC4,YBX3,MAP3K14,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,TBRG4,APTX,PTK2,NOP58,MMAA,POLR2A,ECH1,YIF1A,FBXO21,KLHL22,ZDHHC11,HNRNPH3,RNF138,PGAM5,LRRC41,STK4,PHF3,MVK,FEM1C,NF1,PTPRA,CERS5,FANCD2,TRPM6,RCHY1,ZNF107,PLOD1,BCOR,SIRT2,SLC29A1,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,MRPS30,SRPRB,ANAPC1,YLPM1,LONRF2,ATG3,ANAPC10,HYAL1,IPP,RELB,JOSD1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,PRKACB,TRIP13,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,LVRN,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,TAF9B,CHAF1A,UBTF,GEMIN5,PAF1,UBE3D,SUFU,GATA6,TRMT5,MKL2,PQBP1,ABCC3,GALNT10,COPS6,ZNF397,NOCT,DMTF1,EMSY,LDAH,PIGN,CHST11,AK2,FN1,TAF1,SEC24D,PAX2,GPAT3,DPF2,ALG8,MED13L,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,ATXN2,BANF1,BUD31,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,ISG15,MYBBP1A,INTS5,HK2,EXOC4,RRAGA,ZFP90,PDSS2,ZBTB24,ASH1L,CSTA,PUDP,ZSCAN5A,FARSA,BRE,LYPLAL1,CAMTA2,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TSPAN14,HTRA2,TMLHE,MCEE,ACSL5,PTBP2,TFCP2,PARP2,SFSWAP,NLN,PUSL1,WARS,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,DISP1,USP11,TSPAN5,YDJC,KLHL24,TNIK,SULT1C2,SH2D3A,DBF4,TKFC,PPHLN1,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,HAS3,KDELC1,SHMT2,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,HSPA1B,RERE,ZNF708,ALG5,CUL2,ZRANB2,NCBP2,PREPL,TATDN1,MMP16,ZAK |
| 8.176e-28 | -62.37 | RNA metabolic process | biological process | GO:0016070 | 3387 | 638 | 16441 | 2138 |
ASCC1,THOC5,WDR74,DCP1B,AARS2,HLTF,CCNL2,ZNF44,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ZNF148,KDM5C,SRRM2,ZNRD1,FTSJ3,HMBOX1,RNMT,NFIA,RFX2,WDHD1,C5AR1,RBM28,ZNF197,DDX3X,ZNF266,SUPT4H1,SSU72,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,DHX37,INTS7,ALKBH8,ZNF326,MED24,GEMIN4,PRMT5,ZNF518B,PABPC1,PPA1,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,TYW1,ZNF512B,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,GTF2A1,CLASRP,RPL28,CDK9,CCDC85B,ZNF160,CNOT6,WDR33,ZNF516,TRERF1,DDX18,GTF2H2C,NPAS2,NUP43,SAFB2,ZMAT2,UBL5,RPP30,BCAS2,ERI1,ZKSCAN1,WAC,INTS12,TRMT12,ZC3H3,LSM10,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,MEF2D,FGFR1,PES1,TAF2,KDM4B,ELP2,HIPK2,POLR3E,HOXA3,FUS,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RNASEH2B,RSRC1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,SOX6,HNRNPM,DIS3L2,DDX24,ZNF467,FOXC1,DDX49,UBC,TRIB3,TOE1,NSD1,RARS,SRCAP,BAZ2B,ARID3B,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,BIRC2,HNRNPLL,SCAF8,SRSF2,PHF5A,DHX33,TRMU,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,BRCA1,ZNF91,MLLT10,GLS,TCF7L1,TP53BP1,CHD3,PER1,E2F4,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,FOXO1,HSD17B10,LAMTOR3,SMAD7,HES6,BARX2,ZFP36L1,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,PAXBP1,USP49,TLE3,SETD2,UTP15,RNH1,SUPT5H,TCF7L2,NR2F1,PWP1,PRPF40B,ATXN7,SYNCRIP,TBPL1,ZNF430,DTD1,DDX10,SART1,ID1,PAPD4,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,ZNF83,ZNF709,TNKS1BP1,PELP1,ZNF121,KDM1A,METTL16,NRF1,ZBTB21,DUS4L,NUP133,RNF2,ZFP37,ETF1,AHCYL1,PRPF19,SKIV2L,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,NUP214,ZNF251,EXO1,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ATG7,ZNF436,INTS9,PUS1,MED20,ZNF18,PPIL3,ZNF507,NIFK,RFX1,AGO2,VARS,FOXP1,ZNF594,ZNF561,CWC27,DDX31,POLR1B,SNAPC5,TRNP1,FOXN3,ZNF654,ZMYM5,DHX34,POLR3A,POLR3G,L3MBTL3,ZBTB8OS,ADAT2,TAF4,TBX3,CSRNP1,BCAS3,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,PRKAB2,DDX19A,PLRG1,GABPB2,AARS,MGA,LPIN1,RPS16,RNF111,CHD2,TRMT10A,MEIS3,SEH1L,ZNF646,SNU13,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,DENND4A,SON,SAP30BP,CLNS1A,GZF1,SKIL,TRRAP,CCNT1,LUC7L3,ZNF81,HIC2,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,LARS2,ZHX3,PRPF31,GTF2IRD1,PRPF39,CHD5,HR,ZNF586,SCAF1,MYC,GTF3C3,CNOT4,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,ZNF425,ASCC3,EPRS,HIF1A,SPEN,ZBTB12,MED15,ZCCHC6,PURB,NCOR1,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,NOP56,TERF2IP,CHD7,ZNF827,PUS3,KDM2A,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,SATB2,MED16,PNN,SETD7,DHX57,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,SMARCC1,G6PD,ZNF236,MBTD1,FTSJ1,TRMT2A,ALKBH1,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,FARS2,MYNN,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,UPF2,HARS2,CELF1,EXOSC4,YBX3,FAM120B,TSHZ1,TTLL5,APEX1,KLF6,NOP58,POLR2A,ZFP62,ZNF155,DDX50,HNRNPH3,ATM,DDIT3,KAT6A,ZNF76,PHF3,ATRX,KMT2E,RARS2,ZNF107,PPIL1,BCOR,SIRT2,SNAPC4,EDC3,SMARCB1,YLPM1,JAZF1,GPATCH1,ZEB1,RELB,POLR3B,YARS,CARM1,TRIP13,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,ZNF680,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,GEMIN5,PAF1,GATA6,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,ZCCHC8,PAX2,DPF2,MED13L,SMG7,DDIT4,ELL,ZNF354A,ATXN2,BUD31,NRIP1,POLR1E,CPSF3L,ZNF629,VOPP1,ZNF234,TRA2A,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,LIG4,PRDM1,POP1,MYBBP1A,BICD1,INTS5,RRAGA,CDKAL1,ZFP90,TBL1X,AGO3,NR2C2AP,ZBTB24,TCF12,ASH1L,PBX1,SMARCA4,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,MAML3,NARS2,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,METTL2A,POU2F1,ATXN1,METTL15,DKC1,PUSL1,WARS,BATF3,IKZF4,DUS3L,ADNP,HNRNPR,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SUPT6H,PPHLN1,ATF7IP,MED18,MRPS11,CTNNBL1,ERI3,FBL,DMRT1,PKNOX1,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,ZNF324B,SCMH1,MARS,MEN1,ZNF407,SYMPK,TARS,CTIF,ZNF221,RERE,ZNF708,ZRANB2,NCBP2,POLR1C,NFKBIB |
| 3.794e-27 | -60.84 | organic substance metabolic process | biological process | GO:0071704 | 8992 | 1398 | 16441 | 2138 |
PTP4A1,GGT1,ADAM19,THOC5,DPH1,DCP1B,AARS2,MRPL10,CCNL2,ZNF44,HMOX2,SLC6A8,ABHD6,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,ATP5G2,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,UPP1,EHMT1,NFIA,WDHD1,C5AR1,MCM2,ZNF197,PYCR1,SSU72,RAD18,BDH2,RIOK1,RUNX1,ZNF532,BANP,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,GEMIN4,MRPL21,PABPC1,PPA1,MYB,ZNF675,GATAD2B,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,ST6GALNAC3,TRIM37,SRA1,USP46,RDH11,IRS1,KPNA1,GSTO2,NME7,RPL28,EHMT2,CCDC85B,BPNT1,SRP14,C18orf25,GALE,SDSL,GTF2H2C,PAFAH1B1,DDR2,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,ZSWIM7,ACD,WAC,MMP14,INTS12,MSH4,PXK,MGLL,TRMT12,ZC3H3,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,KCNH3,MEF2D,SLC35D1,DSP,NUDT15,MAT2A,FBXL5,KDM4B,ELP2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,MORC2,COMMD10,HMGA2,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,TAF3,UNC13A,ACOT11,LTN1,PTGS1,ZNF710,FBXL19,RPL22L1,SPTAN1,VPS37A,DDX24,USP42,LDHA,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,MTMR1,CYP24A1,CUL7,TRIM16,SLC25A21,SCAF8,HNRNPLL,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,HKR1,TRIML2,ZNF3,ZMYM2,RBCK1,AEBP2,ATF4,PPARG,CDK4,HSPA5,TSN,SUMO3,KCNH2,ODC1,DLST,MLLT10,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,E2F4,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,BEND6,USP15,CTU2,FOXO1,CLK1,PRSS3,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,VAPB,CTR9,ICE2,PNPLA3,LRSAM1,WARS2,USP49,SETD2,OBSCN,ACOXL,TCF7L2,PRPF40B,CASS4,DTD1,GGT7,PTP4A2,DDX10,BCCIP,USP7,SART1,MPI,ID1,SUCLG1,PAPD4,ARID2,NTSR1,SLC2A1,RPS29,LAGE3,RIPK1,DENND3,TNKS1BP1,ZNF121,FDX1,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,AHCYL1,SPIDR,PRPF19,KDM3B,RAB7A,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,ZNF507,DMGDH,NIFK,ESCO1,MINK1,MCM10,HM13,AUH,RFX1,AGO2,APRT,VARS,FOXP1,SLC25A20,ADH5,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,TOP3A,EXOG,POLR3A,SMPDL3B,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,SUCLG2,DPH6,CHD2,CSGALNACT2,ZNF646,ACADS,GDAP1,ZDHHC14,SON,DENND4A,CLNS1A,PLCXD2,SPOP,OSBPL1A,DOT1L,GZF1,DDAH2,TRRAP,CCNT1,SH3RF1,NSMCE1,LUC7L3,CFD,HIC2,XPNPEP1,BLMH,BMI1,SPOCK2,SPOCK3,PRPF38B,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,NDUFS7,HR,USPL1,SCAF1,MYC,PIGG,CNOT4,FDFT1,EXOSC2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,ARID1A,NELFA,TPRA1,MTR,ZNF850,ANGPTL4,PHF6,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,ZNF254,BIRC6,UROD,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,NOP56,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,PCMT1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,TRAF3,SETD6,XRCC4,SSH2,BRAF,B4GALT5,FARS2,RPS6KA5,INPP1,GIGYF2,SFR1,ABL1,ELP5,CELF1,DYNC2H1,CLK2,PXN,TTLL5,APEX1,PSAT1,AGPAT4,ADSL,GUF1,KLF6,SLC23A2,ZFP62,RETSAT,DDX50,ZNF155,COQ9,ORC5,ATM,NDUFS5,APAF1,ADK,DDIT3,KAT6A,IMMP2L,ZNF76,PIGM,EIF3C,KMT2E,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,KANSL1,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,SLC35C2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,FBXW4,ZNF195,SIRT6,ITPA,TFPI,MINA,KSR2,MTHFD1L,PITPNB,SGK2,KMT2C,ST3GAL5,MPC1,TIMM44,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,ZCCHC8,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,RNF141,ELL,P3H1,ZNF354A,ISPD,TENM3,ATP6V0D1,MTHFD1,HSD17B14,ZNF629,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,CORIN,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,TBCK,PDE9A,AGO3,NR2C2AP,TCF12,DLL4,CEMIP,TNXB,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,CBR4,FHIT,ADCK4,UTP4,AUP1,MAML3,NARS2,PRAME,METTL2A,GRHL3,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,ALAD,DUS3L,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,PDE4B,MED18,IGF2BP2,ATF7IP,CHCHD10,PIP4K2A,GFM2,PEX7,SEC24C,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,SULT4A1,SCMH1,ZNF324B,PDE2A,PEAK1,EIF5B,ZNF221,CTIF,SERINC1,DAGLB,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,ASCC1,WDR74,CACNA1H,HLTF,NT5C3A,NUP160,SYNJ1,PABPC4,TOM1L1,SREBF2,NEK6,PMAIP1,NSRP1,FAAH2,FNIP2,ZNF148,FXN,CDK6,PTPRM,RFX2,MSRB3,DCUN1D5,RBM28,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIP1L1,RBP1,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,SLK,SIRT7,PLA2G12A,RSF1,YARS2,ABCA7,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,PRMT5,ZNF518B,COQ3,AGL,MAP3K12,HMGCR,FADS1,PEA15,BDNF,GTF2H3,TIMM8B,COL17A1,RB1CC1,PRDM16,EIF4A2,ZNF512B,SMARCD3,IMPDH2,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,ZNF783,TASP1,CLASRP,GTF2A1,CDK9,SURF1,ZNF160,CNOT6,SENP3,WDR33,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,NPAS2,ATP6V1A,PDK4,MYH9,TUBB6,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ZKSCAN1,ERI1,PYCRL,ATRIP,GSTA4,NT5C,MTHFD2L,LSM10,PERP,GARS,STAMBP,NPM3,ATF7IP2,ADAM32,ATP6V0A1,FKBP3,FGFR1,PDE8B,PES1,TAF2,CDC16,HIPK2,PEMT,PAM,FUS,BRCC3,ZBTB11,YEATS2,TRIM36,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,TADA3,NPRL2,SUV39H2,GATC,SOX6,HNRNPM,LYPLA2,DIS3L2,DDHD1,FGF9,POLK,MRPS10,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,RPA1,TRIB3,RARS,ETFDH,TOE1,BAZ2B,POLE2,STX1A,ARID3B,PTPN4,PSAP,GPAM,ANAPC4,KDM4C,SRM,GPBP1L1,PPARGC1B,POLR1A,TFIP11,MFGE8,HECTD3,CSNK2A1,RNF43,COX10,SEC16A,BIRC2,ABL2,DHX33,PHKA1,TRMU,XRCC2,PPCDC,POLE3,RAN,ZNF85,ETV1,MPST,PTPRK,SF3A1,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,SKIV2L2,ZNF414,BAZ2A,HARS,GDPD1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,ZNF91,MGST1,KIF16B,GLS,MSRA,TP53BP1,PER1,EEFSEC,SOCS4,RAD51B,TNFRSF1A,DLX2,CHMP4C,SEPHS2,XYLB,AOC3,TTN,SARS,MCM6,PGPEP1,HSD17B10,HES6,ZFP36L1,BARX2,RLF,RNF40,TRMT13,PDE10A,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,CAMKK2,TRAPPC9,CRADD,PAXBP1,TLE3,UTP15,RNH1,MEX3B,TRAPPC6B,SUPT5H,NR2F1,VAC14,PGD,PWP1,ATXN7,FAM135A,SPAG9,SYNCRIP,PALB2,IRAK2,TBPL1,ZNF430,HMBS,BRSK2,NAPA,TESC,RNF114,NDUFA5,CYLD,LPCAT2,RBFOX2,PPP2R2A,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,ZBTB21,DUS4L,UBR1,ZDHHC6,IKBKB,RNF2,ETF1,ZFP37,HIBCH,PRMT3,CASP10,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,NARS,THSD4,CPOX,AKAP13,ENC1,NUP214,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ABHD3,ZNF436,PUS1,ZNF18,PPIL3,MAP3K13,CSNK1A1,RMI1,ZNF594,PTPN2,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,SELT,FBXO31,CD44,PCK2,HSD17B12,ADAMTSL3,GINS3,ZNF654,ZMYM5,DHX34,TEX14,HIST1H4J,PIK3CB,NEU1,ZRANB3,POLR3G,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,MYRF,RPS6KC1,GCSH,POLB,MYCBP2,PRDX6,TNFRSF21,PRKAB2,DDX19A,PLRG1,ADAMTS6,AARS,UBR5,MGA,RPS16,RNF111,ME1,TRMT10A,MEIS3,FUT11,SEH1L,SNU13,DPF3,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,DESI1,SAP30BP,SKIL,ZNF81,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,EGR1,ZHX3,AK6,GTF2IRD1,CCDC47,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,PI4KB,ENTPD5,ZNF586,COPS3,ATIC,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,AOC2,POLA1,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,NSF,UBAP1,D2HGDH,ZBTB12,RIOK3,PURB,UMPS,PEX13,MACROD1,MAP2K4,ZFHX2,PTCD2,LIN28B,ZBTB37,HFM1,NDUFB5,OLA1,KLHL18,FOSL2,PDE3A,PHC2,TERF2IP,FLAD1,CHD7,ZNF827,PUS3,KDM2A,SHC1,UCHL5,SSBP1,PNPLA4,SERPINH1,KMT2A,RFC4,RFC3,PDK1,MTIF2,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,VDR,TAMM41,DNAJA3,ZNF236,H2AFX,ACP1,TRMT2A,ALKBH1,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,LIAS,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,NEDD4,DCTPP1,ZNF239,ZNF483,COMMD9,PTRF,NISCH,PMPCA,PHYKPL,HARS2,COPS7B,UPF2,NLGN3,EXOSC4,YBX3,MAP3K14,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,TBRG4,APTX,PTK2,NOP58,MMAA,POLR2A,ECH1,YIF1A,FBXO21,KLHL22,COL26A1,ZDHHC11,HNRNPH3,RNF138,PGAM5,LRRC41,STK4,PHF3,MVK,FEM1C,NF1,PTPRA,CERS5,FANCD2,TRPM6,RCHY1,ZNF107,PLOD1,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,MRPS30,SRPRB,ANAPC1,LONRF2,YLPM1,ATG3,ANAPC10,RELB,HYAL1,IPP,JOSD1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,LVRN,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,CHAF1A,TAF9B,UBTF,GEMIN5,PAF1,UBE3D,SUFU,GATA6,TRMT5,MKL2,PQBP1,ABCC3,GALNT10,COPS6,ZNF397,NOCT,DMTF1,EMSY,TNRC6A,LDAH,PIGN,CHST11,AK2,FN1,TAF1,SEC24D,PAX2,DPF2,GPAT3,ALG8,MED13L,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,ATXN2,BANF1,BUD31,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,ISG15,MYBBP1A,INTS5,HK2,EXOC4,RRAGA,ZFP90,PDSS2,ZBTB24,ASH1L,SLC5A5,CSTA,PUDP,ZSCAN5A,FARSA,BRE,LYPLAL1,CAMTA2,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TSPAN14,TMEM14C,HTRA2,TMLHE,MCEE,ACSL5,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,NLN,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,DISP1,USP11,TSPAN5,YDJC,KLHL24,TNIK,SH2D3A,SULT1C2,DBF4,TKFC,PPHLN1,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,HAS3,KDELC1,SHMT2,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,HSPA1B,RERE,ZNF708,ALG5,CUL2,ZRANB2,NCBP2,PREPL,TATDN1,MMP16,ZAK |
| 5.377e-27 | -60.49 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | 7542 | 1204 | 17775 | 2278 |
ARHGAP26,GGT1,CDCP1,DCP1B,AARS2,SBF2,ABHD6,LPAR3,CIAPIN1,SKI,PDZD2,ZFHX3,AP1M1,MAD1L1,KDM5C,HMBOX1,NRAS,RNMT,LIMA1,UPP1,EHMT1,NFIA,KIF15,C11orf80,WDHD1,C5AR1,ABCC2,ZNF197,SLC7A1,AHNAK,RAD18,LRRC40,RUNX1,VASH2,ZNF532,SLC25A26,TMEM63C,TRIO,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,CHN1,RBM20,APLF,WDR60,CCDC88C,SAMD3,MYB,NOM1,RABEPK,LRRC20,GATAD2B,ZNF675,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,USP10,ST6GALNAC3,SNAP25,TRIM37,USP46,DYNC1H1,KPNA1,NME7,PDLIM1,EHMT2,TRAP1,KIAA0196,PDLIM5,ARHGAP10,RAB11FIP4,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,CD99L2,FAM122B,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,NDUFB3,ZBED2,CD96,SPG21,ACD,TBC1D22A,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,PCNXL2,KCNH3,GSTCD,SLC35D1,DSP,MAT2A,ZFAND3,FBXL5,ARHGAP21,KDM4B,ASTN2,NSMCE2,POLR3E,CAMKMT,MORC2,COMMD10,HMGA2,SHQ1,IP6K2,PSMF1,TTLL11,TAF3,CFDP1,UNC13A,ACOT11,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,SAMD4A,TTPAL,ZC4H2,ZC3H18,NXN,CCDC150,NSD1,ACOX1,SORCS2,MTMR1,CYP24A1,RBM33,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,AMPD3,ECM1,PHF5A,COPS4,NCKIPSD,ANKRD11,METTL8,ZMYM2,FAM184A,VPS13B,DSC3,MIOS,PPARG,ANK2,SUMO3,LAMA2,KCNH2,KRTCAP2,CRYBG3,LSG1,CXADR,BSN,DYRK1B,HPRT1,TCF7L1,CHD3,E2F4,DPP4,ADAM9,PPP3CC,TSEN2,USP15,ITFG1,NKD2,MAPK8IP3,ARID1B,SUB1,RNFT2,CEP290,MBD2,NDRG4,VAPB,CTR9,PNPLA3,LRSAM1,SNX29,IFT43,SETD2,HAUS6,OBSCN,ACOXL,TCF7L2,TBC1D2,GRIK4,SNX24,CASS4,SIL1,DTD1,DDX10,SH3PXD2A,BCCIP,OLFM2,PAPD4,UPK3B,ARID2,NDUFAF2,NTSR1,SLC2A1,RIPK1,SSBP2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PAG1,DDX60L,URB1,ZNF608,NRF1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,AHCYL1,KDM3B,SOBP,ARHGAP17,AKAP8L,TEX19,KIRREL2,NHSL1,EIF3H,EXO1,KLF4,ATG7,EIF2B3,MUTYH,PARD3,DMGDH,AUH,VARS,RBM19,FOXP1,POGZ,ADH5,TMEM161A,SNAPC5,MON1A,FOXN3,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,POLR3A,CDH24,CACNB1,SAMD5,NOL10,L3MBTL3,TAF4,BCAS3,FNTB,RBM26,KIF1B,C6orf223,GYG1,PRKCA,LRP5L,LPIN1,EXOC1,ZFYVE28,SPAG6,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,SON,DENND4A,DDX60,PLCXD2,DOT1L,OSBPL1A,TRRAP,LSM14A,SH3RF1,HSPBAP1,NRP1,WDR66,BLMH,SPOCK3,SPOCK2,ZMAT3,NMD3,PRPF38B,JUP,LARS2,DLGAP4,TATDN3,SSR4,MTUS1,FAM192A,TECTA,HR,SLC7A11,LDOC1L,SCAF1,PIGG,CAV2,FDFT1,PRIM2,KIAA1143,PCCA,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,SLC26A11,MTR,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,MED15,BIVM,ZCCHC6,C7orf50,NCOR1,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,PABPC1L,FLNB,RING1,SLX4,LPIN2,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,GON4L,C1orf228,PREX1,LRRC8A,SATB2,MARCH6,SETD7,ERC1,HSD3B7,SNCA,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,LARGE,IFT140,SLC4A7,TRAF3,TBXA2R,MID1,SSH2,BRAF,B4GALT5,FARS2,RCAN1,DNAJC22,OPA1,GIGYF2,PHLDA2,ABL1,NEBL,DYNC2H1,CELF1,NAV3,TMC7,TTLL5,PSAT1,ZFYVE1,AGPAT4,PACS1,BMS1,SLC23A2,IREB2,DDX50,COQ9,ORC5,ATM,SVIL,APAF1,ADK,IPO4,IMMP2L,LETM1,LYRM4,ATRX,RARS2,SLC30A7,DST,CNIH3,JAZF1,MYH3,ZEB1,GPATCH1,B3GNTL1,CARM1,CEP128,DTNB,TNK2,DEAF1,FBXW4,SESN2,SKAP2,SIRT6,TFPI,MINA,KSR2,COTL1,MTHFD1L,SGK2,KMT2C,CCDC3,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,CSMD3,ASB3,DCAF5,ZCCHC8,VTA1,STXBP6,QSER1,EVPL,ELL,HVCN1,ISPD,CCDC124,ZCCHC7,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,PPAT,ELOVL6,ELP3,JMJD1C,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,SYCP2L,BICD1,KIAA0355,FSCN1,FAT1,KIAA0754,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,PDE9A,DMXL2,TCF12,FEZ2,PSTPIP2,TMEM183A,SMARCA4,COBLL1,ARSJ,PIBF1,DHX35,RIOK2,ZC3H13,RRN3,MPHOSPH10,NVL,PPFIBP1,SNTG2,FHIT,ITGAX,VCL,TMEM120B,AUP1,MAML3,NARS2,RTN4RL2,ANTXR2,PRAME,GRHL3,ATXN1,MRRF,UBR4,ARMC4,KPNA3,ARNTL,FKBP5,TMEM101,RNF130,NFRKB,SMG1,TMCC1,SUPT6H,ARL15,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,SEMA3E,MFHAS1,FAM49A,BMP6,PIP4K2A,PEX7,SEC24C,DCTN4,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,KDM5A,SCFD2,ASAP3,PDE2A,NAALADL2,CTIF,ZNF221,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,NFKBIB,ZSWIM6,CACNA1H,CSPP1,HLTF,NUP160,NOS1AP,AMBRA1,PABPC4,PCDH7,TOM1L1,NSRP1,FAAH2,RASSF3,RABGAP1L,PDS5B,WIZ,AVEN,CNTNAP3B,CDK6,PTPRM,WLS,RFX2,AKAP12,PLEKHM3,DCUN1D5,C10orf76,RBM28,SLC50A1,DDX3X,BRCA2,FIS1,HERC2,CARS,EP400,CLDN15,TRIP6,SIRT7,NHS,RSF1,SLC1A1,SLC39A11,SH2B3,KIAA1671,SLC38A5,MCM5,CACNB2,ALKBH8,ZNF326,CALN1,FMNL2,SERBP1,GTF2H3,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,MBNL2,EVI5,CPT1A,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,LEMD3,CNOT6,WDR33,MB21D2,COG5,SPRED2,ZNF516,DNM3,ABCA3,TRERF1,DDX18,NPAS2,ACTR3,MYH9,TUBB6,EEA1,RPP30,PRKD3,ABCA12,ERI1,ATRIP,CEP63,PERP,MALL,GARS,STAMBP,ARHGEF10,ADAM32,TTC28,FGFR1,PDE8B,PES1,IQCH,PEMT,HIPK2,WDR7,BRCC3,ANKS1A,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,SESTD1,TRAK1,WDR37,BHLHE40,RSRC1,MBNL1,KRI1,PVRL3,ACAP3,SOX6,DIS3L2,C21orf58,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,R3HDM2,ZNF467,UBE2K,PDE3B,CASC1,RPA1,RARS,BAZ2B,PXDN,POLE2,ARID3B,PTPN4,SLC25A19,SLCO5A1,GPAM,PSAP,IGBP1,DOCK6,KDM4C,ANAPC4,CORO2B,BCAS4,GPBP1L1,POLR1A,PPARGC1B,HECTD3,CSNK2A1,RNF43,COX10,SEC16A,GIT2,ARHGAP18,PHKA1,MARVELD2,XRCC2,UBAP2L,MPST,PTPRK,TMPO,FLNC,CHD9,GCNT2,SLC3A2,ABCC4,SKIV2L2,KATNAL1,GDPD1,MED27,NOL6,BRCA1,PEX1,KIF16B,GLS,MSRA,ZNF622,TP53BP1,PER1,EEFSEC,TECPR2,CCDC146,SOCS4,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,AOC3,SARS,MCM6,STX8,LRRC28,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,PPIL2,GTF2H1,SYNJ2,ALDH18A1,GMDS,NT5E,NAA38,TRAPPC9,LAMC1,CRADD,WDR25,ZNFX1,TRAPPC6B,VAC14,PGD,FAM135A,PALB2,DNAH17,ZNF430,PPP1R12B,ARHGAP12,HMBS,TESC,PRKAR2A,NDUFA5,CYLD,LPCAT2,GPR143,LPCAT3,PELP1,KDM1A,CAD,UBR1,FSIP2,DNAJB6,HIBCH,ETF1,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,KAT8,SEC24A,WDR36,NARS,GLTSCR2,THSD4,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,USP36,BTBD11,SMAD3,RBBP8,CLEC16A,ZNF333,ABHD3,ITGA2,ZNF436,TSSC1,NFASC,AP2S1,PKIB,UNC13D,C14orf159,MAP1S,ZNF346,RMI1,BZW2,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,CWC27,PRICKLE2,GREB1,DDX31,CD44,HSD17B12,ADAMTSL3,DHX34,RAP1GDS1,C11orf49,GPNMB,PIK3CB,CHCHD6,ARMC3,CENPP,ZRANB3,POLR3G,MKX,TPD52L2,C20orf196,TMEM237,SRBD1,ZBTB8OS,ADAT2,GLG1,RWDD2B,ITGB4,RPS6KC1,MIPOL1,CGN,TNFRSF21,TMEM109,ENAH,UBR5,AARS,MGA,RPS16,VPS52,ME1,CEP135,SEH1L,SLC38A6,NR6A1,ALDH1L2,GNG7,EYA3,CUX1,SEMA3F,MAK16,SAP30BP,VPS13D,GREB1L,DNAH2,SEMA3C,ZNF598,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,ANKRD17,OPHN1,GTF2IRD1,PID1,CD226,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ASAP1,COPS3,SAMD13,GTF3C3,LPCAT1,ADARB1,SCAF11,SIK3,DDX28,TTYH2,PTPN12,RABAC1,PLCB1,ZNF425,EPRS,KIDINS220,SRRD,NSF,PMEPA1,D2HGDH,IQSEC2,MACROD1,MAP2K4,RTTN,PTCD2,AMOTL1,TRPM2,LIN28B,HFM1,OLA1,C1QTNF7,SPATS2L,FOSL2,PDE3A,TRIM66,PHC2,CHD7,ZNF827,KDM2A,UCHL5,GLYR1,PNPLA4,KMT2A,NAA35,ATP6AP1L,ZCCHC14,MPP6,SFXN4,WDPCP,MED16,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,ZNF236,ANXA2,MDN1,TROVE2,NCOR2,UTP14A,TTC27,C10orf2,TCF3,NFX1,SLC25A12,RTN4,MON2,IKBKAP,FOXO3,NEDD4,ZNF483,RGS17,PTRF,NISCH,RDX,UPF2,NLGN3,PLEKHG4,FAM120B,PFKFB4,WDFY3,OASL,ECH1,FBXO21,ZDHHC11,HELZ,STX18,RNF138,MYOM2,PGAM5,BRWD3,STK4,SLC43A1,SLC37A3,PHF3,MVK,FEM1C,NF1,KIF5A,FANCD2,TRPM6,PLOD1,ZNF107,ANKRD18A,BCOR,STK33,SNAPC4,CUTC,AHCYL2,SMARCB1,WNT2B,MRPS30,ZNF804A,RTN1,ANAPC1,LONRF2,THADA,ZNHIT6,ANAPC10,RELB,IPP,POLR3B,SLC27A5,TRIM14,LAMA4,GPM6A,TXLNG,CMIP,SLC38A1,GPCPD1,HDAC8,CAV1,TCTN1,SERGEF,CHAF1A,CDHR3,PAF1,RHOU,TMEM132B,UBTF,EPN2,GATA6,SUFU,MKL2,PQBP1,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,VIPR1,CHST11,PIGN,FN1,TAF1,SEC24D,DPF2,MED13L,XPO7,RHBDD1,ETFB,CEP164,SIPA1L3,ATXN2,SEMA3D,N4BP2,POLR1E,VOPP1,RANBP6,PDE4A,TBXAS1,WWC1,C11orf65,ZSCAN16-AS1,ANKRD20A4,DNAH14,UBAP2,ATAD5,SDCCAG8,HK2,EXOC4,KIAA1328,TMEM182,PDSS2,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,MYO7A,ST7L,UBTD2,GBF1,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,CPSF3,MET,HN1,MOSPD1,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,PARP2,SFSWAP,NLN,R3HDM1,RAB10,RAD54B,WARS,TPK1,HYAL3,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,TSPAN5,KLHL24,TNIK,SULT1C2,DBF4,NSUN6,H2AFJ,CLSTN2,LETMD1,CCDC7,PPP1R1C,SFI1,MAN1A1,IL17RE,PRKCH,CTNNBL1,DSG2,TANK,KDELC1,CLDND1,TTC17,UTS2,DMRT1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,ZNF407,SYMPK,RERE,MFN2,ALG5,MPP7,CUL2,ZRANB2,TATDN1,ZAK,MMP16,ARHGAP27,SLC16A10 |
| 2.934e-26 | -58.79 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | 941 | 237 | 17758 | 2279 |
SRM,WDR74,PPARGC1B,DDX19A,TMEM109,ENAH,ANKRD18A,SLC29A1,IKBIP,STK33,HMOX2,NUP160,CUTC,MAP2K3,CIAPIN1,IKZF5,THADA,DHX33,THAP4,ATG3,TRMU,UBAP2L,METTL8,PAK1IP1,PCOLCE2,PRADC1,FXN,CDK6,TRIP13,TRIM14,PRKACB,SEH1L,TIMM50,ELOF1,DEAF1,ABCC4,TXLNG,KLHL23,GNL3,ATOX1,AP4B1,PACRGL,NOL6,MINA,DCUN1D5,SOX4,FLVCR1,RBM28,GEMIN5,LSS,RAD18,INSIG1,TRMT5,LUC7L3,ARL4A,SYNGR2,RIOK1,FAM118A,WDR75,C9orf78,IFT57,EGR1,PRPF31,HES6,TIMM10,PDCD5,LYRM2,FKBP1A,MCAM,DHX37,SLC38A5,MYC,GTF2H1,MED24,CCDC124,GEMIN4,NOC3L,ALDH18A1,MRPL21,GMDS,PRMT5,LPCAT1,COQ3,LRP3,PRPS1,FMNL2,SERBP1,MYB,RABEPK,SCAF11,MSI2,TIMM8B,PDE4A,WDR61,MYO10,XPO5,RDH10,UTP15,C19orf70,POP1,PWP1,TSR1,TASP1,MYBBP1A,SYNCRIP,TRAP1,FSCN1,CCDC85B,SLC16A1,SQLE,SENP3,UMPS,C7orf50,IFITM2,DHCR7,DDX10,C12orf45,C18orf25,ZBTB24,BCCIP,USP7,MPI,DDX18,LPCAT2,SLC2A1,KLHL18,TMEM177,ISG20L2,URB1,UBL5,RPAIN,RPGRIP1L,NOP56,ZSCAN5A,METTL16,FARSA,TMEM150C,CYB5D1,GLYR1,MGLL,TMEM120B,MTHFD2L,PRMT3,LYST,SAP30,HN1,ACSL5,WDR36,MPP6,SFXN4,NPM3,NLN,DKC1,DHX57,ATP5D,DCBLD2,PES1,SLC39A14,ELP2,DUS3L,DCXR,TIMM17A,PEMT,FTSJ1,ATG7,SRFBP1,HEATR1,SCARB1,NOLC1,PDCD11,FGFBP3,BAG1,DNAJA4,B4GALT5,C10orf2,MRI1,TCF3,SLC25A12,VARS,IKBKAP,BZW2,HDDC2,DCTPP1,NPRL2,SACS,GART,PSMG4,NOP16,CFDP1,TRIAP1,PMPCA,DDX31,COPS7B,POLR1B,EXOSC4,ERI3,FBL,LDLRAD3,ACTR3B,RPL22L1,NUDC,FAM98A,SLC40A1,TRNP1,ERICH1,DDX24,MON1A,FOXN3,ABCF2,SCFD2,SLC35G1,LDHA,RANGAP1,CCDC113,IL6R,APTX,EIF5B,C8orf33,RHOT2,MRPL36,POLR3G,INF2,NOL10,ZDHHC11,WDR35,ZNF330,ADAT2,SLC25A19,DNAJC12,RBM26,NCBP2,PGAM5,POLR1C,NR2F2,GCSH,IPO4,GPATCH4 |
| 5.941e-26 | -58.09 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 16161 | 2193 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.520e-25 | -57.15 | metabolic process | biological process | GO:0008152 | 9879 | 1501 | 16441 | 2138 |
PTP4A1,GGT1,ADAM19,THOC5,DPH1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,CCNL2,ZNF44,HMOX2,SLC6A8,ABHD6,CIAPIN1,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,ATP5G2,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,UPP1,EHMT1,NFIA,KIF15,WDHD1,C5AR1,ABCC2,MCM2,ZNF197,PYCR1,SSU72,RAD18,BDH2,MPV17,RIOK1,RUNX1,ZNF532,BANP,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,GEMIN4,MRPL21,PABPC1,PPA1,MYB,ZNF675,GATAD2B,ALG6,WDR61,STAG1,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,ST6GALNAC3,SNAP25,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,KPNA1,GSTO2,NME7,RPL28,EHMT2,FGFBP1,CCDC85B,BPNT1,SRP14,C18orf25,GALE,SDSL,GTF2H2C,PAFAH1B1,SUGCT,DDR2,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,ZSWIM7,ACD,WAC,MMP14,INTS12,MSH4,PXK,MGLL,TRMT12,ZC3H3,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,KCNH3,MEF2D,SLC35D1,DSP,NUDT15,MAT2A,FBXL5,KDM4B,ELP2,METTL6,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,MORC2,COMMD10,HMGA2,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,TAF3,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,ZNF710,FBXL19,RPL22L1,SPTAN1,VPS37A,DDX24,USP42,LDHA,NXN,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,MTMR1,CYP24A1,CUL7,TRIM16,SLC25A21,SCAF8,HNRNPLL,FRRS1,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,RBCK1,AEBP2,ATF4,PPARG,CDK4,HSPA5,TSN,SUMO3,KCNH2,ODC1,DLST,LSG1,MLLT10,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,E2F4,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,BEND6,USP15,CTU2,FOXO1,CLK1,PRSS3,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,VAPB,CTR9,ICE2,PNPLA3,LRSAM1,CWF19L2,WARS2,USP49,SETD2,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,PRPF40B,CASS4,DTD1,GGT7,PTP4A2,DDX10,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,SUCLG1,PAPD4,ARID2,NDUFAF2,NTSR1,SLC2A1,RPS29,LAGE3,RIPK1,DENND3,TNKS1BP1,DDX60L,ZNF121,FDX1,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,MYH15,AHCYL1,SPIDR,PRPF19,KDM3B,RAB7A,CA5B,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,FAHD1,MUTYH,ZNF507,DMGDH,NIFK,ESCO1,MINK1,MCM10,HM13,AUH,RFX1,AGO2,APRT,VARS,FOXP1,SLC25A20,ADH5,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,ABCF2,TOP3A,EXOG,POLR3A,SMPDL3B,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,KIF1B,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,SUCLG2,DPH6,CHD2,CSGALNACT2,ZNF646,ACADS,GDAP1,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,PLCXD2,SPOP,OSBPL1A,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,SH3RF1,NSMCE1,LUC7L3,CFD,HIC2,XPNPEP1,BLMH,BMI1,SPOCK2,SPOCK3,PRPF38B,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,NDUFS7,HR,USPL1,SCAF1,MYC,PIGG,CNOT4,FDFT1,EXOSC2,ANAPC13,RREB1,PRIM2,PCCA,RDH10,RAPGEF4,ARID1A,NELFA,TPRA1,MTR,ZNF850,ANGPTL4,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,ZNF254,BIRC6,UROD,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,NOP56,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,PREX1,PCMT1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,TRAF3,SETD6,XRCC4,MID1,VWA8,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,OPA1,RPS6KA5,INPP1,GIGYF2,SFR1,ABL1,ELP5,CELF1,DYNC2H1,CLK2,PXN,TTLL5,APEX1,PSAT1,AGPAT4,ADSL,GUF1,KLF6,SLC23A2,ZFP62,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,NDUFS5,APAF1,ADK,DDIT3,KAT6A,IMMP2L,ZNF76,PIGM,LYRM4,EIF3C,KMT2E,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,KANSL1,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,B3GNTL1,SLC35C2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,FBXW4,ZNF195,SIRT6,ITPA,TFPI,MINA,KSR2,MTHFD1L,PITPNB,SGK2,KMT2C,ST3GAL5,MPC1,TIMM44,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,ZCCHC8,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,RNF141,ELL,P3H1,ZNF354A,ISPD,TENM3,ATP6V0D1,MTHFD1,HSD17B14,ZNF629,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,CORIN,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,TBCK,PDE9A,AGO3,NR2C2AP,TCF12,DLL4,CEMIP,TNXB,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,CBR4,FHIT,ADCK4,UTP4,GNG5,AUP1,MAML3,NARS2,PRAME,METTL2A,GRHL3,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,ALAD,DUS3L,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,KLC4,PDE4B,MED18,CHCHD10,ATF7IP,IGF2BP2,ENOX1,PIP4K2A,GFM2,PEX7,SEC24C,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,KDM5B,GPHN,FGF2,ZNF821,KDM5A,PSPC1,SULT4A1,METTL23,SCMH1,ZNF324B,PDE2A,PEAK1,EIF5B,ZNF221,CTIF,SERINC1,DAGLB,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,GNB3,ASCC1,WDR74,CACNA1H,HLTF,CHAC1,NT5C3A,NUP160,SYNJ1,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,FAAH2,FNIP2,ZNF148,FXN,CDK6,PTPRM,RFX2,MSRB3,DCUN1D5,RBM28,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,FIS1,FIP1L1,RBP1,MEF2C,CARS,HERC2,EP400,TRIP6,KHDRBS1,SLK,SIRT7,PLA2G12A,RSF1,YARS2,ABCA7,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,PRMT5,ZNF518B,MAP3K12,COQ3,AGL,HMGCR,FADS1,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,PRDM16,EIF4A2,ZNF512B,SMARCD3,IMPDH2,ONECUT2,MBNL2,CPT1A,ABCF1,ZNF655,ZNF783,TASP1,GTF2A1,CLASRP,CDK9,SURF1,ZNF160,GPN1,SENP3,CNOT6,WDR33,PLPP6,DNM3,ZNF516,MAP2K5,ABCA3,TRERF1,DDX18,ATP6V1A,NPAS2,PDK4,MYH9,TUBB6,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,ERI1,PYCRL,ATRIP,GSTA4,NT5C,MTHFD2L,LSM10,PERP,GARS,STAMBP,NPM3,ATF7IP2,ADAM32,ATP6V0A1,FKBP3,FGFR1,PDE8B,PES1,GNG2,TAF2,CDC16,HIPK2,PEMT,PAM,FUS,BRCC3,ZBTB11,YEATS2,TRIM36,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,TADA3,NPRL2,SUV39H2,GATC,SOX6,HNRNPM,LYPLA2,DIS3L2,DDHD1,FGF9,CLYBL,POLK,MRPS10,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,RPA1,TRIB3,TOE1,RARS,ETFDH,BAZ2B,PXDN,POLE2,PLPPR2,STX1A,ARID3B,PTPN4,PSAP,GPAM,NUDT22,ANAPC4,KDM4C,SRM,GPBP1L1,PPARGC1B,TFIP11,POLR1A,MFGE8,HECTD3,CSNK2A1,RNF43,COX10,SEC16A,BIRC2,ABL2,DHX33,PHKA1,TRMU,XRCC2,PPCDC,ZNF85,POLE3,RAN,ETV1,MPST,PTPRK,SF3A1,CDC37,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,ZNF414,BAZ2A,HARS,KATNAL1,GDPD1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,ZNF91,MGST1,KIF16B,PEX1,GLS,MSRA,TP53BP1,PER1,EEFSEC,SOCS4,TNFRSF1A,RAD51B,DLX2,CHMP4C,SEPHS2,XYLB,AOC3,OXNAD1,TTN,SARS,PGPEP1,MCM6,HSD17B10,HES6,BARX2,ZFP36L1,RLF,DNAH1,RNF40,ABCA5,TRMT13,PDE10A,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NT5E,TRAPPC9,CAMKK2,CRADD,PAXBP1,TLE3,UTP15,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,PWP1,ATXN7,FAM135A,SPAG9,SYNCRIP,PALB2,IRAK2,DNAH17,TBPL1,ZNF430,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,ZNF83,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,KDM1A,DENR,METTL16,CAD,ZBTB21,DUS4L,UBR1,ZDHHC6,IKBKB,RNF2,ETF1,ZFP37,HIBCH,PRMT3,CASP10,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,TUBA1A,DDX41,NARS,THSD4,CPOX,AKAP13,ENC1,NUP214,USP36,ATP5D,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ABHD3,ZNF436,PUS1,ZNF18,PPIL3,MAP3K13,CSNK1A1,RMI1,ZNF594,PTPN2,NDUFV1,ZNF561,CWC27,HIST2H3D,DDX31,SELT,FBXO31,CD44,PCK2,HSD17B12,ADAMTSL3,GINS3,ZNF654,ZMYM5,DHX34,TEX14,HIST1H4J,RHOT2,PIK3CB,NEU1,ZRANB3,POLR3G,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,NDUFAF5,MYRF,RPS6KC1,GCSH,CGN,MYCBP2,POLB,PRDX6,PRKAB2,TNFRSF21,DDX19A,PLRG1,ADAMTS6,AARS,UBR5,MGA,GIPR,RPS16,RNF111,ME1,MEIS3,TRMT10A,FUT11,SEH1L,DPF3,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,TCEB3,CUX1,DESI1,FOXRED1,SAP30BP,SKIL,HSDL2,ZNF81,DNAH2,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,DROSHA,EGR1,ZHX3,AK6,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,PI4KB,ENTPD5,ZNF586,COPS3,ATIC,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,AOC2,POLA1,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,NSF,UBAP1,D2HGDH,ZBTB12,RIOK3,PURB,PEX13,UMPS,MACROD1,MAP2K4,ZFHX2,PTCD2,TRPM2,LIN28B,ZBTB37,HFM1,NDUFB5,OLA1,KLHL18,FOSL2,PDE3A,PHC2,TERF2IP,FLAD1,CHD7,ZNF827,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,SSBP1,SERPINH1,PNPLA4,KMT2A,RFC4,RFC3,PDK1,MTIF2,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,TAMM41,VDR,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,LIAS,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,NEDD4,DCTPP1,ZNF239,ZNF483,COMMD9,FTCDNL1,PTRF,NISCH,PMPCA,PHYKPL,HARS2,COPS7B,UPF2,NLGN3,EXOSC4,YBX3,MAP3K14,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,TBRG4,APTX,PTK2,OASL,NOP58,MMAA,POLR2A,ECH1,YIF1A,FBXO21,KLHL22,COL26A1,ZDHHC11,HELZ,HNRNPH3,RNF138,PGAM5,LRRC41,STK4,PHF3,MVK,FEM1C,NF1,PTPRA,KIF5A,CERS5,FANCD2,TRPM6,RCHY1,ZNF107,PLOD1,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,MRPS30,SRPRB,ANAPC1,RAP1A,LONRF2,YLPM1,ATG3,ANAPC10,RELB,HYAL1,IPP,JOSD1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,LVRN,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,CHAF1A,TAF9B,GEMIN5,RHOU,UBTF,PAF1,UBE3D,SUFU,GATA6,TRMT5,MKL2,PQBP1,ABCC3,GALNT10,COPS6,ZNF397,NOCT,DMTF1,EMSY,TNRC6A,LDAH,PIGN,CHST11,AK2,FN1,TAF1,SEC24D,PAX2,DPF2,GPAT3,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,ATXN2,BANF1,BUD31,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,ISG15,DNAH14,MYBBP1A,INTS5,HK2,EXOC4,RRAGA,PTRH2,TRMT10B,ZFP90,PDSS2,ZBTB24,ASH1L,SLC5A5,MYO7A,CSTA,PUDP,GBF1,ZSCAN5A,FARSA,BRE,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,MET,ZNF460,TSPAN14,TMEM14C,HTRA2,TMLHE,MCEE,ACSL5,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,NLN,ATP8B2,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,DISP1,USP11,ECHDC1,TSPAN5,YDJC,KLHL24,TNIK,SH2D3A,SULT1C2,NSUN6,DBF4,TKFC,PPHLN1,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,HAS3,KDELC1,SHMT2,DMRT1,SLC25A1,MSX1,TEAD1,PSMC3IP,MARS,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,HSPA1B,RERE,MFN2,ZNF708,ALG5,CUL2,ZRANB2,NCBP2,PREPL,TATDN1,ZAK,MMP16 |
| 1.659e-24 | -54.76 | cellular macromolecule metabolic process | biological process | GO:0044260 | 6741 | 1094 | 16441 | 2138 |
PTP4A1,THOC5,DPH1,DCP1B,AARS2,MRPL10,CCNL2,ZNF44,SKI,ZNF37A,IKZF5,ZFHX3,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,EHMT1,NFIA,WDHD1,C5AR1,MCM2,ZNF197,SSU72,RAD18,RIOK1,RUNX1,ZNF532,BANP,TRIO,PIK3R4,PDCD7,PARN,CDC73,RBM20,UBE3A,DHX37,APLF,MED24,GEMIN4,MRPL21,PABPC1,PPA1,MYB,ZNF675,GATAD2B,ALG6,WDR61,STAG1,ZNF587,ARID5B,TYW1,ATAT1,USP10,ST6GALNAC3,TRIM37,SRA1,USP46,IRS1,KPNA1,RPL28,EHMT2,CCDC85B,SRP14,C18orf25,GTF2H2C,DDR2,NUP43,ST3GAL6,ZMAT2,MCM9,UBL5,ZSWIM7,ACD,WAC,INTS12,MSH4,PXK,TRMT12,ZC3H3,PMS1,KMT2D,ZNF480,EIF3J,KCNH3,MEF2D,SLC35D1,DSP,FBXL5,KDM4B,ELP2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,COMMD10,HMGA2,GAS6,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,TAF3,LTN1,ZNF710,FBXL19,RPL22L1,SPTAN1,VPS37A,DDX24,USP42,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,SRD5A3,BMP4,MTMR1,CUL7,TRIM16,SCAF8,HNRNPLL,MAP2K3,SRSF2,PHF5A,COPS4,HKR1,TRIML2,ZNF3,ZMYM2,RBCK1,AEBP2,ATF4,PPARG,CDK4,HSPA5,TSN,SUMO3,KCNH2,MLLT10,DYRK1B,TCF7L1,CHD3,E2F4,PRPF4,PPP3CC,TSEN2,BEND6,USP15,CTU2,FOXO1,CLK1,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,CTR9,ICE2,LRSAM1,WARS2,USP49,SETD2,OBSCN,TCF7L2,PRPF40B,CASS4,DTD1,PTP4A2,DDX10,BCCIP,USP7,SART1,MPI,ID1,PAPD4,ARID2,RPS29,LAGE3,RIPK1,DENND3,TNKS1BP1,ZNF121,NRF1,JAG1,NUP133,GRIN2C,AHCYL1,SPIDR,PRPF19,KDM3B,RAB7A,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,ZNF507,NIFK,ESCO1,MINK1,MCM10,RFX1,AGO2,VARS,FOXP1,ADH5,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,TOP3A,EXOG,POLR3A,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,DPH6,CHD2,CSGALNACT2,ZNF646,ZDHHC14,SON,DENND4A,CLNS1A,SPOP,DOT1L,GZF1,TRRAP,CCNT1,SH3RF1,NSMCE1,LUC7L3,HIC2,BLMH,BMI1,SPOCK2,SPOCK3,PRPF38B,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,HR,USPL1,SCAF1,MYC,PIGG,CNOT4,EXOSC2,ANAPC13,RREB1,PRIM2,ARID1A,NELFA,ZNF850,PHF6,CAT,SEC31A,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,NCOR1,SMYD3,HS2ST1,ZNF254,BIRC6,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,NOP56,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,TTC3,CDK12,CASP8AP2,SAP30,BRD4,PCMT1,SATB2,MARCH6,SETD7,ERC1,SERP1,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,G6PD,MBTD1,LARGE,FTSJ1,TRAF3,SETD6,XRCC4,SSH2,BRAF,B4GALT5,FARS2,RPS6KA5,GIGYF2,SFR1,ABL1,ELP5,CELF1,CLK2,PXN,TTLL5,APEX1,KLF6,GUF1,ZFP62,DDX50,ZNF155,ORC5,ATM,DDIT3,KAT6A,IMMP2L,ZNF76,PIGM,EIF3C,ATRX,KMT2E,RARS2,PPIL1,SLC30A7,PCYOX1L,CNIH3,KANSL1,JAZF1,ANAPC11,GPATCH1,ZEB1,SLC35C2,YARS,CARM1,SRPK2,DEAF1,TNK2,FBXW4,SESN2,ZNF195,SIRT6,MINA,KSR2,SGK2,KMT2C,ST3GAL5,TIMM44,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,EME1,ZC3H8,DCAF5,FBXO45,ZCCHC8,UBXN1,SMG7,EVPL,TIMM10,RNF141,ELL,P3H1,ZNF354A,ISPD,ATP6V0D1,ZNF629,ZNF234,TRA2A,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,CDKAL1,PFDN2,TBL1X,TBCK,AGO3,NR2C2AP,TCF12,DLL4,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,FHIT,ADCK4,UTP4,AUP1,MAML3,NARS2,PRAME,METTL2A,GRHL3,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,DUS3L,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,MED18,ATF7IP,GFM2,SEC24C,ERI3,FBL,PKNOX1,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,KDM5B,GPHN,FGF2,ZNF821,PSPC1,KDM5A,SCMH1,ZNF324B,PEAK1,EIF5B,ZNF221,CTIF,GADD45A,AGTPBP1,POLR1C,NFKBIB,ASCC1,WDR74,HLTF,NUP160,PABPC4,TOM1L1,SREBF2,NEK6,NSRP1,PMAIP1,FNIP2,ZNF148,FXN,CDK6,PTPRM,RFX2,MSRB3,DCUN1D5,RBM28,STOML2,DDX3X,SUPT4H1,BRCA2,ZNF266,FIP1L1,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,SLK,SIRT7,RSF1,YARS2,ABCA7,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,PRMT5,AGL,MAP3K12,ZNF518B,PEA15,TIMM8B,GTF2H3,RB1CC1,PRDM16,EIF4A2,ZNF512B,SMARCD3,ONECUT2,MBNL2,ABCF1,ZNF655,ZNF783,CLASRP,GTF2A1,CDK9,ZNF160,CNOT6,SENP3,WDR33,ZNF516,ABCA3,MAP2K5,TRERF1,NPAS2,DDX18,PDK4,TUBB6,SAFB2,RPP30,PRKD3,BCAS2,ZKSCAN1,ERI1,ATRIP,LSM10,GARS,STAMBP,NPM3,ATF7IP2,FKBP3,FGFR1,TAF2,PES1,CDC16,HIPK2,FUS,BRCC3,ZBTB11,YEATS2,TRIM36,ZNF786,XPC,TRAK1,SF3A3,ID2,JMJD6,TGFB2,BHLHE40,MBNL1,RSRC1,POM121,TADA3,NPRL2,SUV39H2,GATC,SOX6,LYPLA2,HNRNPM,DIS3L2,FGF9,POLK,MRPS10,ZNF467,UBE2K,DDX49,FOXC1,RPA1,TRIB3,RARS,TOE1,BAZ2B,POLE2,STX1A,ARID3B,PTPN4,ANAPC4,KDM4C,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,SEC16A,BIRC2,ABL2,DHX33,PHKA1,TRMU,XRCC2,POLE3,RAN,ZNF85,ETV1,SF3A1,PTPRK,METTL1,CHD9,GCNT2,ZNF124,ZNF414,BAZ2A,HARS,SKIV2L2,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,ZNF91,KIF16B,GLS,MSRA,TP53BP1,EEFSEC,PER1,SOCS4,RAD51B,DLX2,CHMP4C,TTN,SARS,MCM6,HSD17B10,HES6,BARX2,ZFP36L1,RLF,RNF40,TRMT13,PPIL2,TIMELESS,GTF2H1,SYNJ2,NT5E,CAMKK2,TRAPPC9,PAXBP1,TLE3,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,IRAK2,TBPL1,ZNF430,HMBS,BRSK2,NAPA,RNF114,CYLD,RBFOX2,PPP2R2A,ZNF83,RNF24,ZNF709,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,ZBTB21,DUS4L,UBR1,ZDHHC6,IKBKB,ZFP37,ETF1,RNF2,PRMT3,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,NARS,AKAP13,ENC1,NUP214,USP36,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ZNF436,PUS1,ZNF18,PPIL3,MAP3K13,CSNK1A1,RMI1,ZNF594,PTPN2,ZNF561,CWC27,HIST2H3D,DDX31,SELT,FBXO31,GINS3,ZNF654,ZMYM5,DHX34,TEX14,HIST1H4J,NEU1,POLR3G,ZRANB3,GPC2,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,MYRF,RPS6KC1,MYCBP2,POLB,PRKAB2,DDX19A,PLRG1,AARS,UBR5,MGA,RPS16,RNF111,TRMT10A,MEIS3,FUT11,SEH1L,SNU13,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,SAP30BP,SKIL,ZNF81,CCNB1IP1,PTPN14,WDR75,IFT57,EGR1,DROSHA,ZHX3,GTF2IRD1,CCDC47,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,ENTPD5,ZNF586,COPS3,GTF3C3,TERF2,SCAF11,ADARB1,DDX28,SIK3,SYNGAP1,POLA1,PTPN12,ARIH2,ZNF425,EPRS,NSF,UBAP1,D2HGDH,ZBTB12,RIOK3,PURB,MACROD1,MAP2K4,ZFHX2,PTCD2,LIN28B,ZBTB37,HFM1,KLHL18,FOSL2,TERF2IP,PHC2,CHD7,ZNF827,PUS3,KDM2A,SHC1,UCHL5,SSBP1,KMT2A,RFC4,RFC3,PDK1,MTIF2,DLG4,MED16,PNN,POLG2,STK10,DHX57,VDR,DNAJA3,ZNF236,H2AFX,TRMT2A,ALKBH1,ACP1,NOLC1,PDCD11,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,MYNN,LIAS,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,NEDD4,ZNF239,ZNF483,COMMD9,PTRF,PMPCA,COPS7B,UPF2,HARS2,EXOSC4,MAP3K14,YBX3,NT5M,MBTPS2,FAM120B,TSHZ1,TBRG4,APTX,PTK2,NOP58,POLR2A,YIF1A,FBXO21,KLHL22,ZDHHC11,HNRNPH3,RNF138,PGAM5,LRRC41,STK4,PHF3,FEM1C,NF1,PTPRA,TRPM6,FANCD2,RCHY1,ZNF107,PLOD1,SIRT2,BCOR,STK33,SNAPC4,EDC3,SMARCB1,MRPS30,SRPRB,ANAPC1,YLPM1,ATG3,ANAPC10,HYAL1,IPP,RELB,POLR3B,GALNT18,OGG1,LONP1,PRKACB,TRIP13,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,HDAC8,CAV1,SOX4,ZSCAN2,TAF9B,CHAF1A,UBTF,GEMIN5,PAF1,UBE3D,GATA6,TRMT5,MKL2,PQBP1,GALNT10,COPS6,ZNF397,NOCT,DMTF1,EMSY,CHST11,PIGN,FN1,TAF1,SEC24D,PAX2,DPF2,ALG8,MED13L,RHBDD1,DDIT4,CEP164,ATXN2,BANF1,BUD31,NRIP1,POLR1E,CPSF3L,VOPP1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,ISG15,MYBBP1A,INTS5,EXOC4,RRAGA,ZFP90,ZBTB24,ASH1L,CSTA,ZSCAN5A,FARSA,BRE,LYPLAL1,CAMTA2,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,PTBP2,TFCP2,PARP2,SFSWAP,PUSL1,WARS,RAD54B,ADNP,COPS5,SRFBP1,HEATR1,USP11,KLHL24,TNIK,SH2D3A,DBF4,PPHLN1,MRPS11,MAN1A1,PRKCH,CTNNBL1,HAS3,DMRT1,MSX1,TEAD1,PSMC3IP,MARS,MEN1,ZNF407,SYMPK,TARS,RERE,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,TATDN1,ZAK |
| 4.657e-24 | -53.72 | intracellular non-membrane-bounded organelle | cellular component | GO:0043232 | 3658 | 652 | 17570 | 2233 |
PTP4A1,ARHGAP26,THOC5,ACTG1,WDR74,DCP1B,MRPL10,NAT10,MKS1,TUBE1,CSPP1,HLTF,NUP160,CIAPIN1,PABPC4,NOS1AP,SKI,NEK6,ZFHX3,FAAH2,RASSF3,MAD1L1,PDS5B,FNIP2,ZNRD1,FTSJ3,CDK6,HMBOX1,RNMT,LIMA1,GNL3,EHMT1,KIF15,AKAP12,WDHD1,MCM2,RBM28,TMSB4X,STOML2,DDX3X,AHNAK,BRCA2,RAD18,TPM1,HERC2,TNNC1,EP400,TRIP6,SIRT7,PARN,CDC73,PITPNM1,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ANP32B,GEMIN4,NOC3L,MRPL21,PABPC1,NOM1,PEA15,GATAD2B,WDR61,STAG1,MYO10,IDH3G,RYR2,ATAT1,SMARCD3,MAP7D1,EVI5,SRA1,ONECUT2,ABCF1,ZNF655,IRS1,DYNC1H1,TSR1,NME7,PDLIM1,RPL28,EHMT2,TRAP1,CCDC85B,SENP3,WDR33,PDLIM5,DNM3,RAB11FIP4,MAP2K5,DDX18,PAFAH1B1,BTBD2,C16orf45,ACTR3,MYH9,ISG20L2,TUBB6,NUP43,HSPA1A,RPGRIP1L,RPP30,BCAS2,ACD,ERI1,CEP63,MSH4,PXK,LYST,KRT7,NPM3,ATF7IP2,ARHGEF10,DSP,TTC28,PES1,ARHGAP21,CDC16,MISP,NSMCE2,YEATS2,CEP170,MAPT,TRIM36,HMGA2,SHQ1,XPC,ID2,JMJD6,ATG2B,IP6K2,BHLHE40,MBNL1,KRI1,TTLL11,TADA3,SNW1,POLR3D,SUV39H2,TMSB10,NOP16,CFDP1,ANXA5,ACTR3B,RPL22L1,PNMA1,HNRNPM,DIS3L2,SPTAN1,NUDC,CEP83,VPS37A,DDX24,CEP295,ARHGAP39,MRPS10,CCDC113,FOXC1,MRPL36,RPA1,TOE1,NSD1,POLE2,STX1A,ACOX1,PTPN4,AEN,IGBP1,CORO2B,KDM4C,CUL7,POLR1A,CSNK2A1,NLE1,BIRC2,ABL2,DHX33,NCKIPSD,XRCC2,RAN,POLE3,TMPO,FLNC,DBN1,METTL1,ATF4,SKIV2L2,BAZ2A,CDK4,KATNAL1,ANK2,MED27,NOL6,SUMO3,BRCA1,CCDC28B,KIF16B,BSN,LSS,MSRA,ZNF622,TP53BP1,CHD3,E2F4,ARL4A,CCDC146,RAD51B,AHNAK2,TSEN2,UQCC2,C2CD5,TTN,MCM6,MEX3A,HSD17B10,SMAD7,DNAH1,SPIRE1,RNF40,SUB1,CEP290,MBD2,CTR9,TIMELESS,ICE2,IFT43,HOMER2,SETD2,HAUS6,UTP15,OBSCN,MEX3B,TCF7L2,PWP1,ATXN7,SPAG9,DNAH17,CASS4,PPP1R12B,HMBS,BRSK2,SH3PXD2A,PRKAR2A,ID1,CYLD,LPCAT2,RPS29,SLC2A1,RSL1D1,RADIL,TNKS1BP1,PPP1R9A,PELP1,URB1,RPAIN,KDM1A,NUP133,DNAJB6,HIRIP3,MYH15,RNF2,CORO1A,SPIDR,PRMT3,CTC1,PRPF19,KAT8,WDR36,EVL,TUBA1A,GLTSCR2,RAB7A,VIM,ENC1,PUM3,USP36,SMAD3,IFT81,RBBP8,KLF4,PUS1,SEPT5,PARD3,NIFK,ESCO1,KIZ,MCM10,MIF4GD,AGO2,MAP1S,ZNF346,RBM19,CSNK1A1,POGZ,HIST2H2AB,IQGAP2,SURF2,IFIT5,HIST2H3D,DDX31,POLR1B,FBXO31,SNAPC5,TRNP1,SMARCAD1,TPM4,TEX14,TOP3A,FERMT2,RANGAP1,HIST1H4J,PALLD,PIK3CB,ZRANB3,POLR3G,CENPP,NOL10,MSH3,BCAS3,EIF2S1,FNTB,USP20,RBPJ,XPO6,KIF1B,CGN,MYCBP2,POLB,PLRG1,ENAH,RAC3,RPS16,SUCLG2,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,CEP135,SEH1L,SPAG6,SNU13,SETD1B,NOL8,EYA3,EFHC1,CAMSAP2,HIST1H2BL,DDX60,MAK16,SAP30BP,CLNS1A,SH3GL1,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,NSMCE1,DNAH2,NRP1,CCNB1IP1,TXN2,SYNPO,ZMAT3,NMD3,PTPN14,WDR75,IFT57,DROSHA,JUP,CDC42EP2,ANKRD17,CCDC53,AK6,OPHN1,CENPB,CRACR2A,CHD5,MTUS1,FKBP1A,PRKCE,NAV1,SLC7A11,MYC,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,SIGMAR1,POLA1,RAP1GAP2,KIAA0586,RAP1B,PTPN12,ARID1A,PLCB1,PHF6,SRP68,PURB,NCOR1,RTTN,LIN28B,BIRC6,URB2,OLA1,SPATS2L,PLEK2,POP5,CORO6,HNRNPA3,RING1,FLNB,BLOC1S2,NOP56,TERF2IP,PHC2,CHD7,SLX4,KDM2A,PPID,UCHL5,MRPS27,TTC3,RMDN3,SSBP1,CDK12,RFC4,CFAP221,BRD4,RFC3,WDPCP,DLG4,PNN,SETD7,POLG2,SERP1,SNCA,BAZ1A,DNTTIP1,SMARCC1,DCXR,G6PD,DNAJA3,H2AFX,IFT140,MDN1,ANXA2,PDCD11,XRCC4,NOLC1,MID1,SSH2,NOSTRIN,UTP14A,C10orf2,TCF3,MRI1,NFX1,KIF5C,MLH1,CEP126,NOL3,IKBKAP,MAD2L2,NEDD4,SFR1,ABL1,NEBL,RDX,EXOSC4,S100A14,DYNC2H1,LARP4B,PXN,TTLL5,APEX1,BMS1,APTX,PTK2,OASL,NOP58,POLR2A,YIF1A,KLHL22,DDX50,ORC5,ATM,SVIL,MYOM2,IPO4,KAT6A,NF1,ATRX,KIF5A,FANCD2,SIRT2,CUTC,EDC3,SMARCB1,MRPS30,DST,SRPRB,KANSL1,JAZF1,MYH3,IPP,RELB,LONP1,PRKACB,SRPK2,CEP128,DEAF1,SIRT6,MINA,TMEM216,HDAC8,CAV1,COTL1,TCTN1,ARPC3,YTHDF2,CHAF1A,UBTF,RHOU,EIF4ENIF1,HLCS,RLTPR,PQBP1,EME1,ZC3H8,NOCT,TNRC6A,LDAH,DCTN3,PAX2,DPF2,SMG7,EVPL,TOX4,CEP164,ELL,ATXN2,BANF1,BUD31,CCDC124,NRIP1,ZCCHC7,AKAP11,POLR1E,ATP6V0D1,KRT20,TRA2A,ELP3,WBSCR22,PSMA1,LIG4,DNAH14,POP1,APBB3,MYBBP1A,BICD1,FSCN1,SDCCAG8,SLC16A1,PFDN2,TBL1X,FNBP1L,AGO3,TCF12,ASH1L,PCNT,PSTPIP2,MYO7A,SMARCA4,TBCCD1,PIBF1,GBF1,SBDS,VPS18,RRN3,MPHOSPH10,NVL,RPS6KL1,SNTG2,VCL,UTP4,C6orf89,HTRA2,HN1,ACSL5,PHLDB2,PARP2,DKC1,UBR4,S100A16,PLIN2,ARMC4,IKZF4,HNRNPR,WDR73,ARNTL,HEATR1,ARC,NFRKB,TNIK,KLC4,H2AFJ,PDE4B,PPHLN1,IGF2BP2,SFI1,MRPS11,DCTN4,SHMT2,ERI3,FBL,TTC17,AMOT,MICAL3,TOP1,ARNTL2,PPP1R9B,DNMBP,GPHN,PSPC1,KDM5A,SCMH1,ARHGAP32,MEN1,PEAK1,SYMPK,TARS,HSPA1B,MFN2,WDR35,ZNF330,CUL2,MBD6,POLR1C,PREPL |
| 4.657e-24 | -53.72 | non-membrane-bounded organelle | cellular component | GO:0043228 | 3658 | 652 | 17570 | 2233 |
PTP4A1,ARHGAP26,THOC5,ACTG1,WDR74,DCP1B,MRPL10,NAT10,MKS1,TUBE1,CSPP1,HLTF,NUP160,CIAPIN1,PABPC4,NOS1AP,SKI,NEK6,ZFHX3,RASSF3,FAAH2,MAD1L1,PDS5B,FNIP2,ZNRD1,FTSJ3,CDK6,HMBOX1,RNMT,LIMA1,GNL3,EHMT1,KIF15,AKAP12,WDHD1,MCM2,RBM28,TMSB4X,STOML2,DDX3X,AHNAK,BRCA2,RAD18,TPM1,HERC2,TNNC1,EP400,TRIP6,SIRT7,PARN,CDC73,PITPNM1,DDX56,DHX37,INTS7,APLF,MCM5,ALKBH8,ANP32B,GEMIN4,NOC3L,MRPL21,PABPC1,NOM1,PEA15,GATAD2B,WDR61,STAG1,MYO10,IDH3G,RYR2,ATAT1,SMARCD3,MAP7D1,EVI5,SRA1,ONECUT2,ABCF1,ZNF655,IRS1,DYNC1H1,TSR1,NME7,PDLIM1,RPL28,EHMT2,TRAP1,CCDC85B,SENP3,WDR33,PDLIM5,DNM3,RAB11FIP4,MAP2K5,DDX18,PAFAH1B1,BTBD2,C16orf45,ACTR3,MYH9,ISG20L2,TUBB6,NUP43,HSPA1A,RPGRIP1L,RPP30,BCAS2,ACD,ERI1,CEP63,MSH4,PXK,LYST,KRT7,NPM3,ATF7IP2,ARHGEF10,DSP,TTC28,PES1,ARHGAP21,CDC16,MISP,NSMCE2,YEATS2,CEP170,MAPT,TRIM36,HMGA2,SHQ1,XPC,ID2,JMJD6,ATG2B,IP6K2,BHLHE40,MBNL1,KRI1,TTLL11,TADA3,SNW1,POLR3D,SUV39H2,TMSB10,NOP16,CFDP1,ANXA5,ACTR3B,RPL22L1,PNMA1,HNRNPM,DIS3L2,SPTAN1,NUDC,CEP83,VPS37A,DDX24,CEP295,ARHGAP39,MRPS10,CCDC113,FOXC1,MRPL36,RPA1,TOE1,NSD1,POLE2,STX1A,ACOX1,PTPN4,AEN,IGBP1,CORO2B,KDM4C,CUL7,POLR1A,CSNK2A1,NLE1,BIRC2,ABL2,DHX33,NCKIPSD,XRCC2,RAN,POLE3,TMPO,FLNC,DBN1,METTL1,ATF4,SKIV2L2,BAZ2A,CDK4,KATNAL1,ANK2,MED27,NOL6,SUMO3,BRCA1,CCDC28B,KIF16B,BSN,LSS,MSRA,ZNF622,TP53BP1,CHD3,E2F4,ARL4A,CCDC146,RAD51B,AHNAK2,TSEN2,UQCC2,C2CD5,TTN,MCM6,MEX3A,HSD17B10,SMAD7,DNAH1,SPIRE1,RNF40,SUB1,CEP290,MBD2,CTR9,TIMELESS,ICE2,IFT43,HOMER2,SETD2,HAUS6,UTP15,OBSCN,MEX3B,TCF7L2,PWP1,ATXN7,SPAG9,DNAH17,CASS4,PPP1R12B,HMBS,BRSK2,SH3PXD2A,PRKAR2A,ID1,CYLD,LPCAT2,RPS29,SLC2A1,RSL1D1,RADIL,TNKS1BP1,PPP1R9A,PELP1,URB1,RPAIN,KDM1A,NUP133,DNAJB6,HIRIP3,MYH15,RNF2,CORO1A,SPIDR,PRMT3,CTC1,PRPF19,KAT8,WDR36,EVL,TUBA1A,GLTSCR2,RAB7A,VIM,ENC1,PUM3,USP36,SMAD3,IFT81,RBBP8,KLF4,PUS1,SEPT5,PARD3,NIFK,ESCO1,KIZ,MCM10,MIF4GD,AGO2,MAP1S,ZNF346,RBM19,CSNK1A1,POGZ,HIST2H2AB,IQGAP2,SURF2,IFIT5,HIST2H3D,DDX31,POLR1B,FBXO31,SNAPC5,TRNP1,SMARCAD1,TPM4,TEX14,TOP3A,FERMT2,RANGAP1,HIST1H4J,PALLD,PIK3CB,ZRANB3,POLR3G,CENPP,NOL10,MSH3,BCAS3,EIF2S1,FNTB,USP20,RBPJ,XPO6,KIF1B,CGN,POLB,MYCBP2,PLRG1,ENAH,RAC3,RPS16,SUCLG2,RNF111,PAK1IP1,CHD2,DPH6,TRMT10A,CEP135,SEH1L,SPAG6,SNU13,SETD1B,NOL8,EYA3,EFHC1,CAMSAP2,HIST1H2BL,DDX60,MAK16,SAP30BP,CLNS1A,SH3GL1,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,NSMCE1,DNAH2,NRP1,CCNB1IP1,TXN2,SYNPO,ZMAT3,NMD3,PTPN14,WDR75,IFT57,DROSHA,JUP,CDC42EP2,ANKRD17,CCDC53,AK6,OPHN1,CENPB,CRACR2A,CHD5,MTUS1,PRKCE,FKBP1A,NAV1,SLC7A11,MYC,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,SIGMAR1,POLA1,RAP1GAP2,KIAA0586,RAP1B,PTPN12,ARID1A,PLCB1,PHF6,SRP68,PURB,NCOR1,RTTN,LIN28B,BIRC6,URB2,OLA1,SPATS2L,PLEK2,POP5,CORO6,HNRNPA3,RING1,FLNB,BLOC1S2,NOP56,TERF2IP,PHC2,CHD7,SLX4,KDM2A,PPID,UCHL5,MRPS27,TTC3,RMDN3,SSBP1,CDK12,RFC4,CFAP221,BRD4,RFC3,WDPCP,DLG4,PNN,SETD7,POLG2,SERP1,SNCA,BAZ1A,DNTTIP1,SMARCC1,DCXR,G6PD,DNAJA3,H2AFX,IFT140,MDN1,ANXA2,PDCD11,XRCC4,NOLC1,MID1,SSH2,NOSTRIN,UTP14A,C10orf2,MRI1,TCF3,NFX1,KIF5C,MLH1,CEP126,NOL3,IKBKAP,MAD2L2,NEDD4,SFR1,ABL1,NEBL,RDX,EXOSC4,S100A14,DYNC2H1,LARP4B,PXN,TTLL5,APEX1,BMS1,APTX,PTK2,OASL,NOP58,POLR2A,YIF1A,KLHL22,DDX50,ORC5,ATM,SVIL,MYOM2,IPO4,KAT6A,NF1,ATRX,KIF5A,FANCD2,SIRT2,CUTC,EDC3,SMARCB1,MRPS30,DST,SRPRB,KANSL1,JAZF1,MYH3,IPP,RELB,LONP1,PRKACB,SRPK2,CEP128,DEAF1,SIRT6,MINA,TMEM216,HDAC8,CAV1,COTL1,TCTN1,ARPC3,YTHDF2,CHAF1A,UBTF,RHOU,EIF4ENIF1,HLCS,RLTPR,PQBP1,EME1,ZC3H8,NOCT,TNRC6A,LDAH,DCTN3,PAX2,DPF2,SMG7,EVPL,TOX4,CEP164,ELL,ATXN2,BANF1,BUD31,CCDC124,NRIP1,ZCCHC7,AKAP11,POLR1E,ATP6V0D1,KRT20,TRA2A,ELP3,WBSCR22,PSMA1,LIG4,DNAH14,POP1,APBB3,MYBBP1A,BICD1,FSCN1,SDCCAG8,SLC16A1,PFDN2,TBL1X,FNBP1L,AGO3,TCF12,ASH1L,PCNT,PSTPIP2,MYO7A,SMARCA4,TBCCD1,PIBF1,GBF1,SBDS,VPS18,RRN3,MPHOSPH10,NVL,RPS6KL1,SNTG2,VCL,UTP4,C6orf89,HTRA2,HN1,ACSL5,PHLDB2,PARP2,DKC1,UBR4,S100A16,PLIN2,ARMC4,IKZF4,HNRNPR,WDR73,ARNTL,HEATR1,ARC,NFRKB,TNIK,KLC4,H2AFJ,PDE4B,PPHLN1,IGF2BP2,SFI1,MRPS11,DCTN4,SHMT2,ERI3,FBL,TTC17,AMOT,MICAL3,TOP1,ARNTL2,PPP1R9B,DNMBP,GPHN,PSPC1,KDM5A,SCMH1,ARHGAP32,MEN1,PEAK1,SYMPK,TARS,HSPA1B,MFN2,WDR35,ZNF330,CUL2,MBD6,POLR1C,PREPL |
| 7.337e-24 | -53.27 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7606 | 1197 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,CNTNAP3,DCP1B,MRPL10,NAT10,TUBE1,SBF2,CCNL2,LPAR3,SKI,PDZD2,ZFHX3,THAP4,AP1M1,MAD1L1,SRRM2,CCDC57,HMBOX1,NRAS,LIMA1,AP4B1,KIF15,WDHD1,SHISA5,ABCC2,SLC9A5,SSU72,RAD18,LRRC40,SYNGR2,MPV17,RIOK1,RUNX1,ZNF532,SLC25A26,TMEM63C,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,WDR60,CCDC88C,PPA1,SAMD3,MYB,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,STAG1,ALG6,KCNQ3,ARID5B,TYW1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,DYNC1H1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,KIAA0196,PDLIM5,ARHGAP10,SDSL,RAB11FIP4,C16orf45,VTI1A,DDR2,CD99L2,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,CD96,SPG21,TBC1D22A,SETD5,WAC,MSH4,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,FAM171A2,PCNXL2,DSP,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,CAMKMT,RPS6KB1,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,RNASEH2B,SNW1,TAF3,CFDP1,UNC13A,ANXA5,LTN1,ACTR3B,C15orf41,SAMD4A,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,OXSR1,NSD1,HERC1,ACOX1,SRD5A3,MTMR1,RBM33,WDR13,SLC25A21,FAM13A,SCAF8,MAP2K3,SRSF2,METTL8,TRIML2,SLC25A23,FAM184A,VPS13B,DSC3,PPARG,ANK2,LAMA2,KCNH2,DLST,LSG1,CXADR,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,DPP4,ADAM9,PPP3CC,TSEN2,BEND6,USP15,CLK1,ITFG1,NKD2,MAPK8IP3,FAN1,RNFT2,CEP290,MBD2,NDRG4,VAPB,CCDC167,CTR9,WNT16,PNPLA3,LRSAM1,SNX29,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,CYB5B,TCF7L2,TBC1D2,GRIK4,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,NTSR1,RIPK1,SSBP2,RADIL,SEMA6A,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,JAG1,CCDC40,MYH15,AHCYL1,KDM3B,SOBP,AKAP8L,ANKRD33B,NHSL1,EIF3H,EXO1,ATG7,INTS9,EIF2B3,PARD3,DMGDH,ESCO1,AUH,RFX1,RBM19,FOXP1,POGZ,ANKRD54,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,PALLD,EXOG,SMPDL3B,CDH24,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,RBM26,TAF12,XPO6,KIF1B,LMBRD2,ZNF292,GYG1,PRKCA,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,CHD2,SPAG6,ACADS,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,DDX60,CLNS1A,TMEM206,PLCXD2,GNAI1,OSBPL1A,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,NRP1,TNFRSF10D,WDR66,BLMH,SPOCK3,SPOCK2,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,ST6GAL1,DLGAP4,TATDN3,MTUS1,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,PIGG,FDFT1,EXOSC2,PRIM2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CPT1C,HS2ST1,VMA21,SYT17,KIAA0232,TMEM104,PLEK2,PTPRG,PABPC1L,DECR1,PPID,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,C1orf228,PREX1,LRRC8A,SATB2,MARCH6,MEGF11,SETD7,ERC1,SNCA,BAZ1A,CAMK2D,SMARCC1,LARGE,IFT140,SLC4A7,TRAF3,MID1,SSH2,BRAF,B4GALT5,FARS2,RCAN1,OPA1,INPP1,NEBL,DYNC2H1,CELF1,CLK2,TMC7,FER1L5,TTLL5,PSAT1,ZFYVE1,AGPAT4,PACS1,SLC23A2,RETSAT,DDX50,ORC5,ATM,SVIL,APAF1,ADK,IMMP2L,LETM1,LYRM4,ATRX,RARS2,SLC52A3,SLC30A7,CNIH3,JAZF1,MYH3,ZEB1,GPATCH1,B3GNTL1,SLC35C2,HCFC2,YARS,CARM1,CEP128,DTNB,TNK2,FBXW4,SESN2,SKAP2,ARRDC3,TFPI,VWCE,MINA,KSR2,COTL1,MTHFD1L,SGK2,KMT2C,TIMM44,CCDC3,EIF4ENIF1,HLCS,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,DCAF5,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,QSER1,EVPL,NAMPT,ELL,HVCN1,ZNF354A,ISPD,ZCCHC7,LRP3,ATP6V0D1,AKAP11,HSD17B14,MTHFD1,PPAT,ELOVL6,XPO5,ELP3,ZFP14,EIF2A,CORIN,SYT1,AGAP1,UBE2E1,EXOC6,POP1,SYCP2L,BICD1,KIAA0355,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,PDE9A,DMXL2,FEZ2,PSTPIP2,TNXB,SMARCA4,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,ZC3H13,RRN3,NVL,SNTG2,FHIT,ITGAX,VCL,TMEM120B,MAML3,NARS2,ANTXR2,MRRF,DKC1,UBR4,ARMC4,KPNA3,CEBPZ,ARNTL,DUSP19,FKBP5,TMEM101,RNF130,SMG1,TMCC1,DNAJC2,DYM,CMTM8,PDE4B,VPS45,IGF2BP2,SEMA3E,SOGA1,ENOX1,FAM49A,MFHAS1,GFM2,BMP6,PIP4K2A,PEX7,STC2,DCTN4,LDLRAD3,ERI3,TOP1,SLC6A16,ARNTL2,DNMBP,FGF2,ZNF821,CRIM1,PSPC1,SULT4A1,SCFD2,ASAP3,PDE2A,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,ZSWIM6,ASCC1,CACNA1H,CSPP1,HLTF,NUP160,NOS1AP,AMBRA1,PCDH7,TOM1L1,SREBF2,NSRP1,SYN2,RABGAP1L,FAAH2,RASSF3,PDS5B,ZNF148,HRG,AVEN,CNTNAP3B,CDK6,GNL3,PTPRM,AKAP12,PLEKHM3,C10orf76,RBM28,ZNF266,HERC2,EP400,NHS,RSF1,SLC1A1,YARS2,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,INTS7,ZNF326,ANP32B,AGL,FMNL2,GTF2H3,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,ONECUT2,MBNL2,EVI5,CPT1A,ABCF1,VPS13C,LRP1B,TASP1,CLASRP,GTF2A1,LEMD3,CNOT6,WDR33,MB21D2,COG5,SPRED2,ZNF516,DNM3,ABCA3,TRERF1,DDX18,BTBD2,NPAS2,ATP6V1A,PDK4,ACTR3,MYH9,NECAP1,SAFB2,STAM,EEA1,PRKD3,BCAS2,ABCA12,FMNL1,MALL,GARS,FAM111B,ADAM32,TTC28,FGFR1,PDE8B,CDC16,IQCH,PEMT,HIPK2,WDR7,BRCC3,ANKS1A,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,XPC,SESTD1,TRAK1,WDR37,JMJD6,AKT1S1,BHLHE40,RSRC1,MBNL1,TADA3,PVRL3,SOX6,DIS3L2,NUDC,C21orf58,FBXO17,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FAM126B,UBE2K,PDE3B,CASC1,RPA1,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,PTPN4,SLCO5A1,GPAM,PSAP,DOCK6,ANAPC4,CORO2B,POLR1A,TFIP11,PPARGC1B,HECTD3,CSNK2A1,RNF43,TTI1,COX10,SEC16A,GIT2,ARHGAP18,PHKA1,DHX33,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,CDC37,SF3A1,TMPO,FLNC,METTL1,CHD9,SLC3A2,ABCC4,SKIV2L2,HARS,KATNAL1,GDPD1,MED27,GMFB,FLVCR1,MGST1,KIF16B,PEX1,GLS,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,STX8,LRRC28,ZFP36L1,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,GTF2H1,ALDH18A1,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,UTP15,WDR25,SUPT5H,VAC14,NR2F1,PWP1,SYNCRIP,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,TESC,PRKAR2A,KCTD7,LPCAT2,UBR1,FSIP2,DNAJB6,CYB5D1,ZDHHC6,HIBCH,CORO1A,AKNAD1,PRMT3,SEC24A,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,TMEM123,SLC35F2,AKAP13,NUP214,BTBD11,SMAD3,RANBP2,RBBP8,TIMM17A,CLEC16A,ZNF333,ABHD3,ITGA2,TSSC1,ZNF18,PPIL3,PKIB,UNC13D,MIF4GD,MAP3K13,FAM46B,C14orf159,ZNF346,BZW2,IQGAP2,PTPN2,NDUFV1,ANXA7,CWC27,PRICKLE2,DDX31,CD44,HSD17B12,ADAMTSL3,ZMYM5,TEX14,RAP1GDS1,PEAR1,C11orf49,GPNMB,RHOT2,TMEM175,PIK3CB,CHCHD6,ARMC3,CENPP,MKX,TPD52L2,C20orf196,SRBD1,GPC2,GLG1,EIF2S1,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,PRKAB2,TNFRSF21,ENAH,IKBIP,AARS,UBR5,MGA,RNF111,ME1,CEP135,DPF3,SLC38A6,NR6A1,ALDH1L2,NOL8,CUX1,SEMA3F,SAP30BP,SKIL,HSDL2,VPS13D,GREB1L,DNAH2,SEMA3C,ZNF598,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,CCDC53,ZHX3,ANKRD17,OPHN1,GTF2IRD1,PID1,CD226,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,ZNF586,TSPAN2,ASAP1,COPS3,SLC16A9,SAMD13,GTF3C3,IGF2BP1,LPCAT1,ADARB1,SCAF11,SIK3,AOC2,KIAA0586,TTYH2,PTPN12,PLCB1,ARIH2,LYRM7,EPRS,KIDINS220,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,TBKBP1,TRPM2,LIN28B,RWDD1,RIBC2,URB2,HFM1,SPRYD7,NDUFB5,OLA1,SPATS2L,FOSL2,PDE3A,PHC2,CHD7,ZNF827,SHC1,KDM2A,UCHL5,GLYR1,NAA35,ATP6AP1L,ZCCHC14,MPP6,PDK1,MTIF2,WDPCP,KIAA1586,GALK2,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,YIPF2,ZNF236,ALKBH1,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,TMEM212,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,SLC25A12,MON2,LIAS,MLH1,IKBKAP,REEP5,FOXO3,NEDD4,ZNF483,RGS17,PTRF,LRP2BP,NISCH,PMPCA,COPS7B,RDX,UPF2,NT5M,PLEKHG4,MBTPS2,FAM120B,WDFY3,FZD3,APTX,NOP58,FBXO21,KLHL22,ZDHHC11,HELZ,STX18,MYOM2,BRWD3,STK4,LRRC41,SLC43A1,SLC37A3,PHF3,UBN1,PTPRA,KIF5A,FANCD2,TRPM6,PLOD1,ANKRD18A,SLC29A1,BCOR,STK33,AHCYL2,EDC3,SMARCB1,ZNF804A,RTN1,ANAPC1,THADA,ZNHIT6,ATG3,ANAPC10,RELB,POLR3B,PCOLCE2,OGG1,TRIM14,ZBTB17,LAMA4,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,GPCPD1,HDAC8,ZSCAN2,SERGEF,RHOU,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,SUFU,DNAJC1,MKL2,BBIP1,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,VIPR1,CHST11,PIGN,SEC24D,ALG8,MED13L,PHGDH,CMTM3,RHBDD1,CEP164,SIPA1L3,ATXN2,SEMA3D,GLTP,NRIP1,POLR1E,CPSF3L,VOPP1,WWC1,C11orf65,PRDM1,C19orf70,DNAH14,UBAP2,ATAD5,MYBBP1A,SDCCAG8,HK2,EXOC4,KIAA1328,PDSS2,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,MYO7A,CSTA,UBTD2,GBF1,BRE,CCDC50,LYPLAL1,CPSF3,MET,HN1,TMLHE,ACSL5,COL5A2,PTBP2,FAM172A,TFCP2,SFSWAP,NLN,R3HDM1,ATP8B2,RAD54B,WARS,TPK1,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,TSPAN5,SULT1C2,C17orf80,NSUN6,CLSTN2,CCDC7,PPP1R1C,SFI1,HDDC2,MAN1A1,PRKCH,CTNNBL1,DSG2,TTC17,UTS2,DMRT1,MARS,PHACTR2,LENG8,MEN1,ZNF407,NAPEPLD,SYMPK,RERE,MFN2,ALG5,MPP7,CUL2,PREPL,ZAK,MMP16,ARHGAP27,SLC16A10 |
| 7.656e-24 | -53.23 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 3776 | 673 | 17775 | 2278 |
ADAM19,CDCP1,THOC5,CACNA1H,SBF2,HLTF,NUP160,NOS1AP,TOM1L1,PCDH7,PDZD2,MMP7,ZFHX3,NSRP1,SYN2,FAAH2,RABGAP1L,C12orf76,MAD1L1,PDS5B,WIZ,HRG,FXN,AVEN,SRRM2,NRAS,PTPRM,KIF15,MCL1,PLEKHM3,SLC9A5,BRCA2,RAD18,RUNX1,SLC25A26,ZNF532,MEF2C,CARS,HERC2,EP400,TRIO,NHS,PIK3R4,RSF1,CDC73,ABCA7,SLC39A11,CHN1,DDX56,UBE3A,CNST,INTS7,CCDC88C,AGL,PABPC1,FMNL2,PPA1,SAMD3,RABEPK,LRRC20,BDNF,STAG1,ALG6,KCNQ3,MYO10,RB1CC1,PRDM16,ARID5B,RYR2,USP10,ST6GALNAC3,CPT1A,TRIM37,EVI5,MBNL2,ONECUT2,USP46,NCDN,DYNC1H1,VPS13C,LRP1B,TASP1,NME7,LEMD3,CNOT6,PDLIM5,MB21D2,ARHGAP10,COG5,ABCA3,DNM3,ZNF516,ATP6V1A,NPAS2,PAFAH1B1,BTBD2,VTI1A,DDR2,MYH9,LCLAT1,STAM,RPGRIP1L,PRKD3,CD96,ABCA12,TBC1D22A,WAC,MMP14,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,EIF3J,ARHGEF10,ADAM32,PCNXL2,TTC28,DSP,MAT2A,FGFR1,ZFAND3,FBXL5,ARHGAP21,IQCH,CDC16,ASTN2,NSMCE2,HIPK2,PEMT,CAMKMT,WDR7,ANKS1A,YEATS2,TRIM36,LRCH1,MORC2,COMMD10,HMGA2,SHQ1,SESTD1,XRRA1,ATG2B,TRIM22,RSRC1,MBNL1,PSMF1,KRI1,TAF3,CFDP1,UNC13A,ZNF710,SOX6,HNRNPM,VPS37A,CLYBL,POLK,ZC4H2,ARHGAP39,ZC3H18,FRA10AC1,NXN,RSBN1,CCDC113,PPIP5K2,PDE3B,CASC1,DDX49,OXSR1,ETFDH,NSD1,BAZ2B,PXDN,NME1-NME2,HERC1,SLCO5A1,SLC25A19,PSAP,SORCS2,MTMR1,CORO2B,KDM4C,CYP24A1,MFGE8,SLC25A21,FAM13A,TTI1,TMEM132A,SCAF8,PHKA1,ANKRD11,METTL8,UBAP2L,VPS13B,FLNC,DSC3,DBN1,CHD9,ATF4,ABCC4,MIOS,PPARG,ANK2,MED27,PSMG1,LAMA2,FLVCR1,ZNF91,HPRT1,TCF7L1,MSRA,TP53BP1,CHD3,EEFSEC,TECPR2,RAD51B,ADAM9,PRPF4,MAGI1,BEND6,USP15,SARS,FOXO1,STX8,ITFG1,LRRC28,FAN1,MAPK8IP3,ZFP36L1,BARX2,DNAH1,DOPEY1,CEP290,VAPB,SYNJ2,GMDS,LRSAM1,SNX29,TRAPPC9,CRADD,IFT43,SETD2,WDR25,CYB5B,VAC14,PGD,PWP1,PRPF40B,GRIK4,SNX24,ZNF430,SIL1,DTD1,ARHGAP12,GGT7,DDX10,SH3PXD2A,USP7,NDUFA5,SART1,OLFM2,ARID2,LPCAT2,NTSR1,RSL1D1,LPCAT3,SSBP2,DENND3,RADIL,URB1,DDX60L,PLXNB1,CAD,ANKRD13A,ZNF608,JAG1,NUP133,UBR1,DNAJB6,IKBKB,CCDC40,MYH15,HIBCH,ETF1,CTC1,SKIV2L,SOBP,TLCD1,SEC24A,PCGF3,EVL,NARS,THSD4,ANKRD33B,MANBAL,TMEM123,AKAP13,NUP214,ARL5B,BTBD11,SMAD3,RBBP8,SIX5,KLF4,TIMM17A,CLEC16A,ITGA2,ATG7,TSSC1,INTS9,PARD3,PKIB,DMGDH,AUH,RBM19,ZNF346,FOXP1,ADH5,CWC27,TMEM161A,PRICKLE2,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,ARHGEF12,C11orf49,PALLD,CHCHD6,PIK3CB,ARMC3,SMPDL3B,CENPP,TPD52L2,NOL10,SRBD1,DSC2,BCAS3,FNTB,RBM26,RPS6KC1,KIF1B,MIPOL1,LUZP1,PRDX6,ENAH,PRKCA,UBR5,MGA,EXOC1,ZFYVE28,ME1,PRADC1,SPAG6,NR6A1,ALDH1L2,EYA3,CUX1,VSNL1,PLCXD2,OSBPL1A,GNAI1,TRRAP,HSDL2,SH3RF1,ARL6IP5,LUC7L3,HSPBAP1,VPS13D,GREB1L,DNAH2,SEMA3C,WDR66,TNFRSF10D,NRP1,ZMAT3,NMD3,PTPN14,EFNB2,WDR75,DROSHA,CELSR1,ANKRD17,LARS2,OPHN1,PID1,CD226,MTUS1,ANXA10,PRKCE,NAV1,ZNF586,ASAP1,MYC,PIGG,SLC16A9,SAMD13,PRIM2,IFNGR2,PCCA,RAP1GAP2,PTPN12,ARID1A,PLCB1,EHBP1,MTR,ARIH2,ATP9B,ASCC3,HIF1A,VCAN,SPEN,ZZEF1,MED15,ZCCHC6,SQLE,PEX13,C7orf50,NCOR1,MACROD1,MAP2K4,HS2ST1,RTTN,TRPM2,BIRC6,SPATA2L,OLA1,TMEM104,PTPRG,PABPC1L,FLNB,PDE3A,PHC2,CHD7,KDM2A,VGF,DTNBP1,SHF,CMPK1,ATP6AP1L,CDK12,NAA35,BRD4,WDPCP,SATB2,SETD7,TBC1D16,STK10,ERC1,SNCA,VDR,BAZ1A,CAMK2D,SMARCC1,ZNF236,LARGE,ALKBH1,TRAF3,MDN1,PDCD11,MID1,SSH2,BRAF,TTC27,NFX1,FARS2,RCAN1,MON2,IKBKAP,NEDD4,ABL1,NEBL,RDX,DYNC2H1,MBTPS2,NAV3,TSHZ1,TTLL5,ZFYVE1,WDFY3,AGPAT4,FZD3,PACS1,SLC23A2,ZDHHC11,STX18,RNF138,SVIL,ATM,MYOM2,APAF1,BRWD3,ADK,STK4,IMMP2L,LETM1,FEM1C,NF1,ATRX,FANCD2,PLOD1,AHCYL2,SLC30A7,RTN1,DST,ZNF804A,CNIH3,JAZF1,JOSD1,SLC27A5,CEP128,TIMM50,LAMA4,DTNB,GPM6A,FBXW4,SKAP2,CMIP,ZNF680,VWCE,TMEM216,KSR2,HDAC8,MTHFD1L,PITPNB,KMT2C,SERGEF,CHAF1A,TMEM132B,CCDC3,EPN2,HLCS,DNAJC1,CSMD3,ASB3,CLU,GALNT10,DMTF1,MTCH1,SLC12A7,DCTN3,CHST11,PIGN,RHOBTB1,SEC24D,ZCCHC8,TAF1,STXBP6,MED13L,SMG7,RHBDD1,ELL,HVCN1,SIPA1L3,ZNF354A,ATXN2,ISPD,SEMA3D,ZCCHC7,LRP3,KRT20,ELOVL6,ELP3,EIF2A,PRDM1,CORIN,SYT1,AGAP1,HERPUD1,DNAH14,UBE2E1,EXOC6,POP1,SYCP2L,UBAP2,BICD1,KIAA0355,FAT1,EXOC4,CDKAL1,TMEM117,KIAA1328,PDE9A,PDSS2,DMXL2,PCNT,MMRN2,COBLL1,ST7L,SLC9B2,PIBF1,UBTD2,GBF1,DHX35,BRE,SOCS1,CCDC50,NVL,PPFIBP1,SNTG2,ZNF142,FHIT,ADCK4,MET,VCL,TMEM120B,C6orf89,NARS2,COL5A2,FAM172A,TFCP2,PARP2,NLN,R3HDM1,BATF3,TPK1,ARMC4,ZC3H12A,KPNA3,HNRNPR,SRFBP1,RNF130,TSPAN5,SMG1,TMCC1,TNIK,DYM,CMTM8,PDE4B,DBF4,NSUN6,CLSTN2,IGF2BP2,SEMA3E,CCDC7,BMP6,PIP4K2A,SFI1,HDDC2,MAN1A1,PRKCH,DCTN4,DSG2,TANK,STC2,SHMT2,TTC17,LDLRAD3,SLC25A1,TOP1,KDM6B,DNMBP,FGF2,CRIM1,PSPC1,ASAP3,SCFD2,METTL23,PHACTR2,ZNF407,NAALADL2,TARS,RERE,CTIF,ZNF708,DAGLB,WDR35,MPP7,AGTPBP1,ZAK,MMP16,ZSWIM6 |
| 2.493e-23 | -52.05 | large_cell | COSMIC cancer mutations | large_cell | 15622 | 2136 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,SLC48A1,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,FLNB,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 3.070e-23 | -51.84 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | 471 | 141 | 17758 | 2279 |
ZNF292,MYCBP2,PHF3,ATRX,PTPRA,PRKCA,UBR5,SCAF8,ZNF804A,DST,ZEB1,ZNF148,CEP135,ZMYM2,PRKACB,PTPRK,SRPK2,CHD9,SKIV2L2,CUX1,CAMSAP2,BRCA1,SPOP,SLC7A1,TRRAP,SEMA3C,RUNX1,ANKRD17,ZHX3,LARS2,SLK,TRIO,MED13L,TGFBR2,PARN,IGF2BP3,UBE3A,ATXN2,MBD2,MYC,NRIP1,CNOT4,ADARB1,SIK3,BDNF,IFRD1,LAMC1,CRADD,STAG1,PRIM2,MYO10,SETD2,ARID5B,WWC1,PTPN12,EVI5,TRIM37,EHBP1,AGAP1,TCF7L2,IRS1,ASCC3,FAT1,SPEN,ARHGAP12,TBL1X,FNBP1L,MAP2K4,SGSM3,TCF12,ID1,PAFAH1B1,RBFOX2,C16orf45,PPP2R2A,PIBF1,STAM,FLNB,NVL,SSBP1,MGLL,PRMT3,SEC24A,PMS1,MPP6,COL5A2,PCMT1,R3HDM1,SATB2,MARCH6,ENC1,BAZ1A,SMAD3,KPNA3,G6PD,CLEC16A,WDR7,SLC4A7,MDN1,XRCC4,TSPAN5,CEP170,MID1,ANKS1A,PARD3,NCOR2,AUH,TRAK1,FARS2,KIF5C,OPA1,BHLHE40,TGFB2,GIGYF2,PIP4K2A,MBNL1,FOXO3,NEDD4,PTPN2,UPF2,LARP4B,SAMD4A,MICAL3,DNMBP,FGF2,CRIM1,FOXN3,KDM5A,ANKMY2,FERMT2,R3HDM2,PTK2,KLF6,OXSR1,BAZ2B,HELZ,ORC5,TAF4,RBPJ,NR2F2,KAT6A |
| 3.447e-23 | -51.72 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7663 | 1201 | 17775 | 2278 |
ARHGAP26,ADAM19,CDCP1,DCP1B,SBF2,HMOX2,ABHD6,LPAR3,SKI,PDZD2,ZFHX3,MAD1L1,KDM5C,CCDC57,HMBOX1,NRAS,RNMT,LIMA1,EHMT1,KIF15,C11orf80,WDHD1,SHISA5,ABCC2,PYCR1,SLC7A1,AHNAK,RAD18,LRRC40,SYNGR2,RIOK1,RUNX1,VASH2,ZNF532,SLC25A26,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,PARN,CDC73,RSPRY1,CHN1,RBM20,UBE3A,CNST,APLF,MED24,WDR60,CCDC88C,PABPC1,PPA1,SAMD3,MYB,NOM1,LRRC20,ZNF675,IFRD1,STAG1,WDR61,KCNQ3,ARID5B,TYW1,IDH3G,USP10,ST6GALNAC3,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,KPNA1,GSTO2,NME7,PDLIM1,TRAP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,RAB11FIP4,PAFAH1B1,C16orf45,VTI1A,CD99L2,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,CD96,TBC1D22A,SETD5,WAC,CLCN6,C16orf58,INTS12,MSH4,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,PCNXL2,KCNH3,SLC35D1,DSP,VPS53,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,POLR3E,CAMKMT,RPS6KB1,METTL2B,RAB30,COMMD10,HMGA2,SHQ1,XRRA1,TRIM22,SNW1,TAF3,CFDP1,UNC13A,LTN1,ACTR3B,C15orf41,SAMD4A,DDX24,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SORCS2,MTMR1,CYP24A1,RBM33,SLC25A21,FAM13A,SCAF8,FRRS1,SRSF2,PHF5A,COPS4,TRIML2,SLC25A23,FAM184A,VPS13B,DSC3,MIOS,PPARG,ANK2,PSMG1,LAMA2,KCNH2,DLST,CRYBG3,CXADR,BSN,HPRT1,TCF7L1,LSS,INSIG1,DPP4,ADAM9,C3orf35,PPP3CC,BEND6,USP15,FOXO1,ITFG1,SMAD7,MAPK8IP3,FAN1,RNFT2,MLX,MBD2,VPS72,NDRG4,VAPB,LRSAM1,SNX29,NIPSNAP1,IFT43,OBSCN,METTL22,CYB5B,GRIK4,TTC38,SNX24,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,OLFM2,PAPD4,ARID2,NDUFAF2,NTSR1,SLC2A1,SSBP2,TIGD1,DENND3,RADIL,SEMA6A,DDX60L,URB1,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,JAG1,NUP133,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,PRPF19,KDM3B,SOBP,TLCD1,ANKRD33B,CA5B,NHSL1,EIF3H,EXO1,ATG7,INTS9,MED20,EIF2B3,PARD3,DMGDH,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,CPNE7,C12orf4,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,SMPDL3B,POLR3A,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,BCAS3,FNTB,TMEM219,KIF1B,LMBRD2,PRR4,PRKCA,LPIN1,EXOC1,ZFYVE28,CSGALNACT2,SPAG6,ACADS,OSBP2,C2orf76,VSNL1,EFHC1,ZDHHC14,SON,DDX60,TMEM206,PLCXD2,GNAI1,OSBPL1A,SPOP,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,ARL6IP5,LUC7L3,HSPBAP1,NRP1,WDR66,SPOCK2,NMD3,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,TATDN3,NDUFS7,MTUS1,TECTA,HR,SLC7A11,NOVA2,SCAF1,MYC,RTFDC1,FDFT1,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,ARID1A,EHBP1,SLC26A11,MTR,PHF6,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,SMYD3,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,DECR1,SLX4,PPID,LPIN2,MRPS27,DTNBP1,TTC3,CMPK1,CDK12,SAP30,C1orf228,PREX1,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,SNCA,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,LARGE,IFT140,SLC4A7,MID1,SSH2,BRAF,B4GALT5,FARS2,RCAN1,OPA1,NEBL,DYNC2H1,MS4A15,NAV3,TMC7,FER1L5,TTLL5,AGPAT4,TMEM126A,PACS1,KLF6,GUF1,SLC23A2,ZNF155,DDX50,ORC5,ATM,SVIL,APAF1,ADK,IMMP2L,LETM1,LYRM4,ATRX,RARS2,SLC30A7,PCYOX1L,CNIH3,JAZF1,MYH3,ZEB1,GPATCH1,B3GNTL1,HCFC2,CARM1,CEP128,DTNB,DEAF1,FBXW4,SESN2,SKAP2,ITPA,TFPI,VWCE,MINA,KSR2,COTL1,MTHFD1L,SGK2,KMT2C,ST3GAL5,YTHDF2,ARPC3,CCDC3,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CSMD3,CLU,DCAF5,FBXO45,RHOBTB1,SCART1,ZCCHC8,STXBP6,QSER1,NAMPT,HVCN1,ZNF354A,ISPD,ZCCHC7,LRP3,HSD17B14,MTHFD1,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZFP14,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FAT1,TMEM117,CDKAL1,TBL1X,TBCK,PDE9A,DMXL2,CHMP2A,SMARCA4,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,ZC3H13,RAET1E,SOCS1,NVL,SNTG2,FHIT,ITGAX,VCL,TMEM120B,C6orf89,GNG5,NARS2,NPW,PRAME,ATXN1,MRRF,DKC1,BATF3,ARMC4,KPNA3,HNRNPR,WDR73,ARNTL,DUSP19,FKBP5,RNF130,SMG1,TMEM33,TMCC1,DNAJC2,SUPT6H,CAMK1,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,SEMA3E,PIP4K2A,MFHAS1,FAM49A,GFM2,BMP6,PEX7,SEC24C,STC2,DCTN4,LDLRAD3,ERI3,RPS6KB2,TOP1,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,PSPC1,SULT4A1,SCFD2,ASAP3,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ZSWIM6,WDR74,CSPP1,CHAC1,HLTF,NUP160,NOS1AP,AMBRA1,PCDH7,TOM1L1,C1orf159,SREBF2,SYN2,RASSF3,RABGAP1L,FAAH2,PDS5B,ZNF148,AVEN,FXN,CDK6,GNL3,PTPRM,RFX2,AKAP12,PLEKHM3,MCL1,DCUN1D5,C10orf76,RBM28,TMSB4X,SUPT4H1,HERC2,EP400,KHDRBS1,NHS,RSF1,KCNJ14,SLC1A1,SLC39A11,ABCA7,SH2B3,EIF2S2,KIAA1671,INTS7,CACNB2,NOC3L,CALN1,AGL,FMNL2,HMGCR,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,SMARCD3,RYR2,MBNL2,EVI5,CPT1A,ABCF1,NCDN,ZNF783,VPS13C,LRP1B,TASP1,CLASRP,GTF2A1,LEMD3,CNOT6,WDR33,MB21D2,COG5,SPRED2,ZNF516,DNM3,ABCA3,TRERF1,BTBD2,ATP6V1A,NPAS2,PDK4,ACTR3,MYH9,TUBB6,STAM,EEA1,PRKD3,BCAS2,ABCA12,ATRIP,MALL,FAM111B,LGALS1,ARHGEF10,ADAM32,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,IQCH,PEMT,HIPK2,WDR7,BRCC3,ANKS1A,YEATS2,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,RSRC1,MBNL1,KRI1,TADA3,PVRL3,HNRNPM,SOX6,ULBP1,DIS3L2,NUDC,C21orf58,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,UBE2K,PDE3B,CASC1,RPA1,KISS1R,RARS,BAZ2B,PXDN,ARID3B,STX1A,PTPN4,SLCO5A1,GPAM,IGBP1,DOCK6,CORO2B,POLR1A,PPARGC1B,COX10,BIRC2,GIT2,ARHGAP18,PHKA1,DHX33,MARVELD2,UBAP2L,ZNF85,ETV1,CDC37,TMPO,FLNC,CHD9,ZNF124,SLC3A2,ABCC4,SKIV2L2,KATNAL1,MED27,MGST1,KIF16B,PEX1,GLS,MSRA,TP53BP1,PER1,EEFSEC,CCDC146,TECPR2,RAD51B,TNFRSF1A,SGSM2,RNF214,CHMP4C,XYLB,OXNAD1,MCM6,STX8,LRRC28,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,TRAPPC9,CAMKK2,LAMC1,CRADD,WDR25,SUPT5H,TRAPPC6B,VAC14,PGD,DNAH17,PPP1R12B,ARHGAP12,NAPA,TESC,PRKAR2A,RNF114,CYLD,LPCAT2,GPR143,UBR1,FSIP2,ZDHHC6,HIBCH,ETF1,RNF2,ANO8,ZFP37,CORO1A,AKNAD1,PRMT3,TMEM200A,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,TMEM123,SLC35F2,AKAP13,ARL5B,NUP214,BTBD11,ATP5D,SMAD3,RANBP2,SLC30A3,RBBP8,CLEC16A,ZNF333,ABHD3,ITGA2,ZNF436,TSSC1,MIF4GD,MAP3K13,C14orf159,MAP1S,BZW2,IQGAP2,PTPN2,CWC27,PRICKLE2,DDX31,CD44,FBXO31,HSD17B12,ADAMTSL3,RAP1GDS1,C11orf49,HIST1H4J,PIK3CB,CHCHD6,ARMC3,CENPP,ZRANB3,MKX,TPD52L2,C20orf196,TMEM237,SRBD1,GPC2,ADAT2,GLG1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,CGN,PRDX6,TNFRSF21,ENAH,IKBIP,UBR5,AARS,MGA,RNF111,ME1,CEP135,MEIS3,SEH1L,DPF3,SLC38A6,NR6A1,ALDH1L2,EYA3,CUX1,SEMA3F,SAP30BP,SH3GL1,HSDL2,VPS13D,GREB1L,DNAH2,SEMA3C,TXN2,PTPN14,EFNB2,WDR75,DROSHA,CELSR1,ZHX3,ANKRD17,OPHN1,GTF2IRD1,PID1,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,ENTPD5,TSPAN2,ASAP1,COPS3,SLC16A9,SAMD13,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,KIAA0586,TTYH2,PTPN12,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,KIDINS220,NSF,PMEPA1,ZZEF1,RIOK3,PEX13,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,TRPM2,LIN28B,RIBC2,HFM1,OLA1,KLHL18,SPATS2L,PDE3A,PHC2,FLAD1,CHD7,ZNF827,SHC1,KDM2A,UCHL5,VGF,NBEA,KMT2A,PLEKHA4,NAA35,ZCCHC14,RFC3,MPP6,PDK1,SFXN4,WDPCP,MED16,GALK2,PNN,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,ZNF236,ALKBH1,ANXA2,KLHDC4,MDN1,PDCD11,NOLC1,TMEM212,UTP14A,TTC27,TCF3,MRI1,ZNF280C,SLC25A12,MYNN,RTN4,MLH1,IKBKAP,GDPD5,REEP5,FOXO3,NEDD4,RGS17,COMMD9,LRP2BP,UPF2,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,WDFY3,FZD3,TBRG4,ECH1,FBXO21,KLHL22,HELZ,STX18,RNF138,MYOM2,BRWD3,STK4,LRRC41,SLC37A3,PHF3,PTPRA,FANCD2,PLOD1,ZNF107,ANKRD18A,SIRT2,SNAPC4,AHCYL2,EDC3,SMARCB1,ZNF804A,RTN1,LONRF2,THADA,ZNHIT6,ATG3,ANAPC10,RELB,IPP,HYAL1,POLR3B,PCOLCE2,TRIP13,PRKACB,LONP1,TRIM14,LAMA4,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,GPCPD1,HDAC8,CAV1,ZSCAN2,TCTN1,SERGEF,CDHR3,GEMIN5,TMEM132B,EPN2,GATA6,SUFU,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,VIPR1,CHST11,PIGN,FN1,TAF1,SEC24D,ALG8,MED13L,PHGDH,RHBDD1,TOX4,CEP164,SIPA1L3,ATXN2,CCDC112,SEMA3D,GLTP,N4BP2,CPSF3L,VOPP1,KRT20,TBXAS1,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,DNAH14,UBAP2,ATAD5,MYBBP1A,SDCCAG8,HK2,EXOC4,KIAA1328,ZFP90,TMEM182,PDSS2,ASH1L,PCNT,CELSR3,MMRN2,MYO7A,ST7L,GBF1,BRE,CCDC50,LYPLAL1,CPSF3,MET,TSPAN14,ZNF460,TMLHE,MOSPD1,ACSL5,COL5A2,PTBP2,FAM172A,TFCP2,SFSWAP,NLN,R3HDM1,ATP8B2,PUSL1,RAB10,RAD54B,WARS,TPK1,ZC3H12A,PLIN2,ADNP,SRFBP1,SLC25A11,SCARB1,DISP1,TSPAN5,KLHL24,TNIK,SULT1C2,DBF4,NSUN6,CLSTN2,CCDC7,PPP1R1C,MFSD10,SFI1,HDDC2,MAN1A1,PRKCH,GART,CTNNBL1,KDELC1,TTC17,DMRT1,PPP1R21,ANKMY2,MARS,PHACTR2,MEN1,ZNF407,NAPEPLD,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,MBD6,TATDN1,ZAK,MMP16,SLC16A10 |
| 5.212e-23 | -51.31 | heterocyclic compound binding | molecular function | GO:1901363 | 5760 | 962 | 16491 | 2164 |
ASCC1,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,HLTF,NT5C3A,ZNF44,SYNJ1,PABPC4,ZNF37A,NEK6,SREBF2,IKZF5,ZFHX3,NSRP1,SYN2,THAP4,PDS5B,ZNF148,KDM5C,HRG,SRRM2,ZNRD1,FTSJ3,CDK6,HMBOX1,EIF4E3,NRAS,RNMT,GNL3,NFIA,KIF15,KRBOX4,RFX2,WDHD1,ABCC2,MCM2,RBM28,TMSB4X,ZNF197,DDX3X,AHNAK,ZNF266,BRCA2,RAD18,BDH2,RIOK1,DIRAS1,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,EP400,TRIP6,SLK,KHDRBS1,TRIO,SIRT7,PIK3R4,PARN,YARS2,ABCA7,RBM20,DDX56,EIF2S2,DHX37,APLF,MCM5,ALKBH8,ZNF326,NOC3L,MRPL21,PRMT5,ZNF518B,MAP3K12,PABPC1,SERBP1,MYB,NOM1,HMGCR,ZNF675,GATAD2B,GTF2H3,MYO10,ZNF587,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,USP10,IMPDH2,MBNL2,ONECUT2,ABCF1,ZNF655,ZNF783,DYNC1H1,TSR1,GTF2A1,NME7,RPL28,TRAP1,LEMD3,CDK9,ZNF160,GPN1,CNOT6,WDR33,SRP14,SDSL,DNM3,MAP2K5,ABCA3,ZNF516,TRERF1,DDX18,NPAS2,ATP6V1A,PDK4,ACTR3,DDR2,MYH9,ISG20L2,TUBB6,SAFB2,ZMAT2,CBWD5,MCM9,HSPA1A,RPP30,ZBED2,PRKD3,ABCA12,ACD,ERI1,ZKSCAN1,CLCN6,NT5C,MSH4,PEG10,PXK,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,EIF3J,NPM3,LGALS1,MEF2D,DSP,FKBP3,MAT2A,FGFR1,PES1,TAF2,ZFAND3,HIPK2,ARL13B,HOXA3,RPS6KB1,CENPBD1,FUS,ZBTB11,RAB30,HMGA2,ZNF786,XPC,SF3A3,JMJD6,IP6K2,BHLHE40,ZNF691,MBNL1,KRI1,TTLL11,SNW1,POLR3D,CBWD6,GATC,SUV39H2,NOP16,PTGS1,ZNF710,FBXL19,ACTR3B,SAMD4A,RPL22L1,SOX6,HNRNPM,DIS3L2,FAM98A,DDX24,POLK,ZC3H18,LDHA,R3HDM2,PPIP5K2,ZNF467,UBE2K,FOXC1,DDX49,UBC,ANXA1,RPA1,OXSR1,TRIB3,TOE1,ETFDH,NSD1,RARS,SRCAP,BAZ2B,PXDN,POLE2,ARID3B,ACOX1,AEN,GPATCH11,GPATCH4,CYP24A1,RBM33,TRIM16,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,SCAF8,HNRNPLL,MAP2K3,ABL2,SRSF2,PHF5A,DHX33,TRMU,XRCC2,HKR1,UBAP2L,ZNF85,RAN,POLE3,ZNF3,ETV1,TMPO,SF3A1,METTL1,CHD9,ZNF124,SLC3A2,ATF4,AEBP2,ABCC4,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,CDK4,KATNAL1,HSPA5,TSN,NOL6,BRCA1,ZNF91,LSG1,MLLT10,KIF16B,PEX1,DYRK1B,HPRT1,ZNF622,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,ARL4A,E2F4,RAD51B,PRPF4,DLX2,TSEN2,MAGI1,SEPHS2,XYLB,CTU2,SARS,TTN,MCM6,FOXO1,CLK1,MEX3A,HSD17B10,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,C1orf52,RLF,DNAH1,ARID1B,RNF40,SUB1,MLX,ZNF358,ABCA5,MBD2,VPS72,PDE10A,SYNJ2,ALDH18A1,GMDS,NT5E,WARS2,CAMKK2,PAXBP1,BCS1L,UTP15,OBSCN,MEX3B,ZNFX1,SUPT5H,CYB5B,ACOXL,NR2F1,TCF7L2,PGD,PRPF40B,SYNCRIP,PALB2,DNAH17,IRAK2,TBPL1,SIL1,ZNF430,DTD1,DDX10,BRSK2,PRKAR2A,BCCIP,SART1,PAPD4,SUCLG1,ARID2,RBFOX2,RIPK1,RSL1D1,ZNF83,SSBP2,ZNF709,TIGD1,PELP1,DDX60L,URB1,ZNF121,KDM1A,DENR,METTL16,CAD,ZBTB21,NRF1,DUS4L,DNAJB6,IKBKB,MYH15,ETF1,ZFP37,CORO1A,AHCYL1,CTC1,SKIV2L,WDR36,TUBA1A,AKAP8L,DDX41,NARS,GLTSCR2,RAB7A,VIM,ARL5B,ZNF251,PUM3,EIF3H,USP36,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,ZNF18,SEPT5,EIF2B3,ZNF589,ZNF507,DMGDH,NIFK,MINK1,MCM10,MIF4GD,AUH,MAP3K13,RFX1,AGO2,ARFIP2,MAP1S,APRT,VARS,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,ZNF594,FAM50A,NDUFV1,ANXA7,ZNF561,IFIT5,HIST2H3D,DDX31,POLR1B,PCK2,TRNP1,SMARCAD1,FOXN3,ZNF654,ABCF2,TEX14,DHX34,TOP3A,HIST1H4J,EXOG,RHOT2,PIK3CB,POLR3A,ZRANB3,MKX,TPD52L2,NOL10,SRBD1,TAF4,SET,TBX3,CSRNP1,MSH3,EIF2S1,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,RPS6KC1,KIF1B,ZNF292,POLB,DDX19A,PRKCA,RAC3,GABPB2,AARS,UBR5,MGA,RPS16,SUCLG2,ME1,CHD2,DPH6,MEIS3,TRMT10A,ZNF646,DDN,ACADS,SNU13,SETD1B,NR6A1,NOL8,TCEB3,CUX1,HIST1H2BL,SON,DENND4A,DDX60,MAK16,CLNS1A,GNAI1,GZF1,DOT1L,SKIL,CCNT1,LSM14A,LUC7L3,ZNF81,HIC2,DNAH2,RFXAP,ZNF598,ZMAT3,NMD3,PRPF38B,WDR75,IFT57,DROSHA,EGR1,PRPF31,ANKRD17,LARS2,ZHX3,AK6,CENPB,GTF2IRD1,CCDC47,PRPF39,TGFBR2,PDCD5,CHD5,IGF2BP3,FKBP1A,PRKCE,HR,PI4KB,ZNF586,NOVA2,SCAF1,MYC,GTF3C3,IGF2BP1,CNOT4,PRPS1,TERF2,SCAF11,ADARB1,SIK3,DDX28,EXOSC2,RREB1,PRIM2,PCCA,POLA1,RAPGEF4,RAP1B,ARID1A,MTR,ZNF850,ARIH2,PHF6,ATP9B,ZNF425,CAT,ASCC3,EPRS,NSF,HIF1A,SPEN,SRP68,ZBTB12,D2HGDH,RIOK3,ZCCHC6,PURB,SQLE,C7orf50,NCOR1,SMYD3,MAP2K4,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,KIAA0232,OLA1,SPATS2L,FOSL2,PABPC1L,LTB4R,HNRNPA3,FLNB,PDE3A,PAIP2,NOP56,TERF2IP,PHC2,CHD7,NUBPL,FLAD1,DECR1,ZNF827,PUS3,ASNS,KDM2A,UCHL5,GLYR1,SSBP1,CMPK1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,ZCCHC14,BRD4,RFC3,GON4L,PDK1,MTIF2,KIAA1586,GNL1,SATB2,GALK2,PNN,POLG2,STK10,DHX57,SNCA,ZBTB25,VDR,DNTTIP1,MSX2,CAMK2D,SMARCC1,G6PD,DNAJA3,ZNF236,H2AFX,TRMT2A,CBWD1,MDN1,ANXA2,PDCD11,NOLC1,XRCC4,TROVE2,VWA8,SSH2,NOSTRIN,NCOR2,BRAF,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,FARS2,KIF5C,RCAN1,MYNN,RTN4,MLH1,OPA1,NOL3,RPS6KA5,GIGYF2,FOXO3,DCTPP1,ZNF239,ABL1,ZNF483,FTCDNL1,PTRF,PHYKPL,HARS2,UPF2,RDX,CELF1,EXOSC4,DYNC2H1,YBX3,LARP4B,MAP3K14,NT5M,NAV3,CLK2,PFKFB4,TSHZ1,TTLL5,APEX1,TBRG4,BMS1,PTK2,APTX,OASL,KLF6,GUF1,MMAA,NOP58,POLR2A,ZFP62,FBXO21,DDX50,ZNF155,IREB2,HELZ,HNRNPH3,ORC5,ATM,APAF1,ADK,DDIT3,KAT6A,STK4,ZNF76,MVK,EIF3C,UBN1,ATRX,RARS2,KIF5A,CERS5,TRPM6,ZNF107,BCOR,SIRT2,STK33,SNAPC4,EDC3,MRPS30,SMARCB1,SRPRB,RAP1A,CMSS1,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,POLR3B,SLC27A5,YARS,OGG1,LONP1,TRIP13,PRKACB,CARM1,TIMM50,SRPK2,ZBTB17,DEAF1,TNK2,ZNF195,SIRT6,ZNF680,ITPA,KSR2,MTHFD1L,SGK2,ZSCAN2,SOX4,KMT2C,TIMM44,YTHDF2,GEMIN5,RHOU,UBTF,EIF4ENIF1,GATA6,HLCS,DNAJC1,CC2D1B,FAM114A2,PQBP1,CRCP,ABCC3,EME1,ZC3H8,ZNF397,NOCT,DMTF1,TNRC6A,AK2,ZCCHC8,RHOBTB1,TAF1,PAX2,DPF2,PHGDH,TOX4,RNF141,ZNF354A,ATXN2,BANF1,CCDC124,NRIP1,ZCCHC7,N4BP2,POLR1E,MTHFD1,ZNF629,MSI2,ZNF234,HBG2,PDE4A,TRA2A,XPO5,ZBED4,TBXAS1,WBSCR22,ZFP14,LIG4,PSMA1,PRDM1,EIF2A,AGAP1,DNAH14,UBE2E1,POP1,UBAP2,MYBBP1A,ATAD5,FSCN1,FDPS,RRAGA,HK2,ZFP90,TBL1X,TBCK,AGO3,ZBTB24,TCF12,ASH1L,MYO7A,SMARCA4,PBX1,SPATS2,DHX35,SBDS,ZSCAN5A,RIOK2,MIEF1,ZC3H13,FARSA,RRN3,MPHOSPH10,CAMTA2,NVL,CBR4,RPS6KL1,ZNF142,FHIT,CPSF3,MET,ZNF460,UTP4,NARS2,ACSL5,PTBP2,TFCP2,PARP2,SFSWAP,GRHL3,R3HDM1,ATXN1,POU2F1,ATP8B2,DKC1,PUSL1,RAB10,S100A16,BATF3,WARS,TPK1,RAD54B,DUS3L,IKZF4,ADNP,HNRNPR,COPS5,ZNF557,ARNTL,CEBPZ,SLC25A11,FKBP5,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,BCKDK,TNIK,DNAJA4,SUPT6H,ARL15,CAMK1,PDE4B,NSUN6,H2AFJ,DBF4,TKFC,PPHLN1,IGF2BP2,ENOX1,PIP4K2A,GFM2,MFHAS1,MRPS11,PRKCH,GART,STC2,SHMT2,ERI3,FBL,DMRT1,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,KDM6B,ARNTL2,MSX1,KDM5B,GPHN,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SCMH1,ZNF324B,MARS,PDE2A,MEN1,PEAK1,EIF5B,ZNF407,TARS,RERE,MFN2,ZNF221,CTIF,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,MBD6,POLR1C,ZAK,HRH1 |
| 6.531e-23 | -51.08 | nucleic acid binding | molecular function | GO:0003676 | 3900 | 698 | 16491 | 2164 |
ASCC1,THOC5,DCP1B,AARS2,MRPL10,NAT10,HLTF,ZNF44,SYNJ1,PABPC4,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,THAP4,PDS5B,ZNF148,KDM5C,SRRM2,ZNRD1,FTSJ3,HMBOX1,EIF4E3,RNMT,GNL3,NFIA,KIF15,KRBOX4,RFX2,WDHD1,MCM2,RBM28,TMSB4X,ZNF197,DDX3X,AHNAK,ZNF266,BRCA2,RAD18,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,EP400,TRIP6,KHDRBS1,PARN,YARS2,RBM20,DDX56,EIF2S2,DHX37,MCM5,ALKBH8,ZNF326,NOC3L,MRPL21,PRMT5,ZNF518B,PABPC1,SERBP1,MYB,NOM1,ZNF675,GATAD2B,GTF2H3,ZNF587,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,IMPDH2,MBNL2,ONECUT2,ABCF1,ZNF655,ZNF783,DYNC1H1,TSR1,GTF2A1,RPL28,TRAP1,LEMD3,CDK9,ZNF160,CNOT6,WDR33,SRP14,ZNF516,TRERF1,DDX18,NPAS2,MYH9,ISG20L2,SAFB2,ZMAT2,MCM9,RPP30,ZBED2,ACD,ERI1,ZKSCAN1,MSH4,PEG10,ZC3H3,LSM10,PMS1,KMT2D,ZNF480,EIF3J,NPM3,LGALS1,MEF2D,DSP,FKBP3,PES1,TAF2,ZFAND3,HOXA3,CENPBD1,FUS,ZBTB11,HMGA2,ZNF786,XPC,SF3A3,JMJD6,BHLHE40,ZNF691,MBNL1,KRI1,SNW1,POLR3D,SUV39H2,NOP16,ZNF710,FBXL19,SAMD4A,RPL22L1,SOX6,HNRNPM,DIS3L2,FAM98A,DDX24,POLK,ZC3H18,R3HDM2,ZNF467,FOXC1,DDX49,UBC,ANXA1,RPA1,TOE1,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,AEN,GPATCH11,GPATCH4,RBM33,TRIM16,GPBP1L1,PPARGC1B,TFIP11,POLR1A,SCAF8,HNRNPLL,SRSF2,PHF5A,DHX33,TRMU,XRCC2,HKR1,UBAP2L,ZNF85,RAN,POLE3,ZNF3,ETV1,TMPO,SF3A1,METTL1,CHD9,ZNF124,SLC3A2,ATF4,AEBP2,SKIV2L2,PPARG,BAZ2A,ZNF414,TSN,NOL6,BRCA1,ZNF91,MLLT10,ZNF622,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,RAD51B,PRPF4,DLX2,TSEN2,CTU2,SARS,MCM6,FOXO1,MEX3A,HSD17B10,SMAD7,FAN1,HES6,BARX2,ZFP36L1,ZIC2,C1orf52,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,MBD2,VPS72,SYNJ2,ALDH18A1,PAXBP1,UTP15,MEX3B,ZNFX1,SUPT5H,TCF7L2,NR2F1,PRPF40B,PALB2,SYNCRIP,TBPL1,ZNF430,DTD1,DDX10,BCCIP,SART1,SUCLG1,ARID2,RBFOX2,RSL1D1,ZNF83,SSBP2,ZNF709,TIGD1,PELP1,DDX60L,URB1,ZNF121,KDM1A,DENR,METTL16,NRF1,ZBTB21,DNAJB6,ZFP37,ETF1,CORO1A,AHCYL1,CTC1,SKIV2L,WDR36,AKAP8L,DDX41,NARS,GLTSCR2,VIM,ZNF251,PUM3,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,ZNF18,EIF2B3,ZNF589,ZNF507,DMGDH,NIFK,MCM10,MIF4GD,AUH,RFX1,AGO2,MAP1S,ZNF346,RBM19,FOXP1,POGZ,HIST2H2AB,ZNF594,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,DDX31,POLR1B,TRNP1,SMARCAD1,FOXN3,ZNF654,DHX34,TOP3A,HIST1H4J,EXOG,POLR3A,ZRANB3,MKX,TPD52L2,NOL10,SRBD1,TAF4,SET,TBX3,CSRNP1,MSH3,EIF2S1,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,DDX19A,GABPB2,AARS,UBR5,MGA,RPS16,CHD2,TRMT10A,MEIS3,ZNF646,DDN,SNU13,SETD1B,NR6A1,NOL8,CUX1,TCEB3,HIST1H2BL,DENND4A,SON,DDX60,MAK16,CLNS1A,GZF1,DOT1L,SKIL,CCNT1,LSM14A,LUC7L3,ZNF81,HIC2,RFXAP,ZMAT3,NMD3,ZNF598,PRPF38B,WDR75,IFT57,DROSHA,EGR1,ZHX3,ANKRD17,PRPF31,CENPB,GTF2IRD1,CCDC47,PRPF39,PDCD5,CHD5,IGF2BP3,HR,ZNF586,NOVA2,SCAF1,MYC,GTF3C3,IGF2BP1,CNOT4,TERF2,SCAF11,ADARB1,EXOSC2,DDX28,RREB1,PRIM2,POLA1,ARID1A,ZNF850,ARIH2,PHF6,ZNF425,ASCC3,EPRS,HIF1A,SRP68,SPEN,ZBTB12,ZCCHC6,PURB,C7orf50,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,SPATS2L,FOSL2,PABPC1L,HNRNPA3,FLNB,NOP56,PAIP2,TERF2IP,PHC2,CHD7,ZNF827,PUS3,KDM2A,UCHL5,GLYR1,SSBP1,SERPINH1,KMT2A,CASP8AP2,SAP30,RFC4,ZCCHC14,BRD4,RFC3,GON4L,MTIF2,KIAA1586,SATB2,PNN,POLG2,DHX57,ZBTB25,SNCA,VDR,MSX2,DNTTIP1,SMARCC1,ZNF236,H2AFX,TRMT2A,ANXA2,PDCD11,XRCC4,NOLC1,TROVE2,SSH2,NOSTRIN,NCOR2,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,FARS2,RCAN1,MYNN,RTN4,MLH1,NOL3,GIGYF2,FOXO3,ZNF239,ABL1,ZNF483,PTRF,HARS2,RDX,UPF2,CELF1,EXOSC4,YBX3,LARP4B,TSHZ1,APEX1,TBRG4,BMS1,APTX,OASL,KLF6,NOP58,POLR2A,ZFP62,FBXO21,DDX50,ZNF155,IREB2,HELZ,HNRNPH3,ORC5,ATM,ADK,DDIT3,KAT6A,ZNF76,EIF3C,UBN1,ATRX,RARS2,CERS5,ZNF107,BCOR,SNAPC4,EDC3,SMARCB1,MRPS30,CMSS1,YLPM1,JAZF1,RELB,ZEB1,GPATCH1,POLR3B,YARS,OGG1,LONP1,CARM1,TIMM50,SRPK2,ZBTB17,DEAF1,ZNF195,ZNF680,ZSCAN2,SOX4,KMT2C,YTHDF2,GEMIN5,UBTF,EIF4ENIF1,GATA6,DNAJC1,CC2D1B,PQBP1,EME1,ZNF397,ZC3H8,NOCT,DMTF1,TNRC6A,TAF1,ZCCHC8,PAX2,DPF2,TOX4,RNF141,ZNF354A,ATXN2,BANF1,CCDC124,NRIP1,ZCCHC7,POLR1E,ZNF629,MSI2,ZNF234,TRA2A,XPO5,ZBED4,WBSCR22,ZFP14,PSMA1,LIG4,PRDM1,EIF2A,POP1,UBAP2,MYBBP1A,FSCN1,FDPS,ZFP90,TBL1X,AGO3,ZBTB24,TCF12,ASH1L,SMARCA4,PBX1,SPATS2,DHX35,SBDS,ZC3H13,ZSCAN5A,FARSA,RRN3,MPHOSPH10,CAMTA2,NVL,ZNF142,CPSF3,ZNF460,UTP4,NARS2,PTBP2,TFCP2,PARP2,SFSWAP,GRHL3,R3HDM1,POU2F1,ATXN1,DKC1,S100A16,PUSL1,BATF3,RAD54B,IKZF4,DUS3L,ADNP,HNRNPR,ZNF557,COPS5,CEBPZ,ARNTL,SLC25A11,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,SUPT6H,NSUN6,H2AFJ,DBF4,PPHLN1,IGF2BP2,ENOX1,GFM2,MRPS11,ERI3,FBL,DMRT1,PKNOX1,CRAMP1,TOP1,ARNTL2,KDM6B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MARS,MEN1,ZNF407,EIF5B,CTIF,ZNF221,RERE,ZNF708,GADD45A,ZRANB2,NCBP2,MBD6,POLR1C,ZAK |
| 1.566e-22 | -50.21 | desmoplastic | COSMIC cancer mutations | desmoplastic | 15554 | 2127 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,AMBRA1,NOS1AP,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,SLC48A1,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,WDR26,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.789e-22 | -50.08 | gene expression | biological process | GO:0010467 | 3868 | 686 | 16441 | 2138 |
GGT1,ASCC1,THOC5,DCP1B,AARS2,MRPL10,HLTF,CCNL2,ZNF44,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,PMAIP1,NSRP1,ZNF148,KDM5C,SRRM2,ZNRD1,FXN,FTSJ3,HMBOX1,EIF4E3,RNMT,NFIA,RFX2,WDHD1,C5AR1,RBM28,ZNF197,STOML2,DDX3X,ZNF266,SUPT4H1,SSU72,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,PDCD7,PARN,CDC73,YARS2,RBM20,DDX56,EIF2S2,DHX37,INTS7,ALKBH8,ZNF326,MED24,ANP32B,GEMIN4,MRPL21,PRMT5,ZNF518B,PABPC1,PPA1,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,TYW1,ZNF512B,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,CLASRP,RPL28,CDK9,CCDC85B,ZNF160,CNOT6,WDR33,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,SAFB2,ZMAT2,UBL5,HSPA1A,RPP30,BCAS2,ERI1,ZKSCAN1,WAC,MMP14,INTS12,TRMT12,ZC3H3,LSM10,PERP,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,MEF2D,FGFR1,PES1,TAF2,KDM4B,ELP2,HIPK2,POLR3E,HOXA3,FUS,ZBTB11,METTL2B,COMMD10,HMGA2,ZNF786,SF3A3,ID2,JMJD6,TRIM22,BHLHE40,RSRC1,PSMF1,MBNL1,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,RPL22L1,SOX6,HNRNPM,DIS3L2,VPS37A,MRPS10,ZNF467,FOXC1,UBC,MRPL36,TRIB3,NSD1,RARS,SRCAP,BAZ2B,ARID3B,KDM4C,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,BIRC2,SCAF8,HNRNPLL,SRSF2,PHF5A,DHX33,TRMU,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SF3A1,METTL1,CHD9,ZNF124,ATF4,AEBP2,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,TSN,MED27,NOL6,BRCA1,ZNF91,MLLT10,GLS,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,PRPF4,DLX2,TSEN2,BEND6,CTU2,SARS,FOXO1,PRSS3,HSD17B10,LAMTOR3,SMAD7,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,TRMT13,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,PAXBP1,CRADD,USP49,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,PWP1,PRPF40B,ATXN7,SYNCRIP,TBPL1,ZNF430,TESC,SART1,ID1,PAPD4,ARID2,RBFOX2,RPS29,LAGE3,PPP2R2A,RIPK1,ZNF83,ZNF709,TNKS1BP1,PELP1,ZNF121,KDM1A,DENR,METTL16,NRF1,ZBTB21,DUS4L,NUP133,RNF2,ZFP37,ETF1,AHCYL1,CASP10,PRPF19,KAT8,KDM3B,WDR36,PCGF3,DDX41,NARS,NUP214,ZNF251,EIF3H,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ZNF436,INTS9,PUS1,MED20,ZNF18,EIF2B3,PPIL3,ZNF507,NIFK,RFX1,AGO2,VARS,FOXP1,ZNF594,ZNF561,CWC27,HIST2H3D,SELT,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,ZNF654,ZMYM5,DHX34,HIST1H4J,POLR3A,POLR3G,L3MBTL3,ZBTB8OS,ADAT2,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,PRKAB2,DDX19A,PLRG1,PRKCA,GABPB2,AARS,LPIN1,MGA,RPS16,RNF111,CHD2,TRMT10A,MEIS3,SEH1L,ZNF646,SNU13,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,DENND4A,SON,SAP30BP,CLNS1A,GZF1,SKIL,TRRAP,CCNT1,LUC7L3,ZNF81,HIC2,BMI1,PTPN14,PRPF38B,IFT57,DROSHA,EGR1,LARS2,ZHX3,PRPF31,GTF2IRD1,PRPF39,SSR4,CHD5,IGF2BP3,FKBP1A,HR,ZNF586,SCAF1,MYC,GTF3C3,IGF2BP1,CNOT4,SCAF11,ADARB1,EXOSC2,RREB1,ARID1A,NELFA,ZNF850,PHF6,ZNF425,ASCC3,EPRS,HIF1A,SRP68,SPEN,MED15,ZBTB12,ZCCHC6,PURB,NCOR1,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,POP5,FOSL2,PABPC1L,HNRNPA3,RING1,NOP56,TERF2IP,CHD7,ZNF827,PUS3,KDM2A,UCHL5,LPIN2,MRPS27,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,MTIF2,SATB2,MED16,PNN,SETD7,DHX57,ZBTB25,SNCA,VDR,BAZ1A,MSX2,DNTTIP1,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,TRMT2A,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,FARS2,MYNN,NOL3,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,PMPCA,UPF2,HARS2,CELF1,EXOSC4,DYNC2H1,YBX3,FAM120B,TSHZ1,TTLL5,APEX1,KLF6,GUF1,NOP58,POLR2A,ZFP62,ZNF155,HNRNPH3,APAF1,DDIT3,KAT6A,IMMP2L,ZNF76,PHF3,EIF3C,ATRX,KMT2E,RARS2,ZNF107,PPIL1,BCOR,SIRT2,SNAPC4,EDC3,SMARCB1,MRPS30,SRPRB,YLPM1,JAZF1,GPATCH1,ZEB1,RELB,POLR3B,YARS,CARM1,TRIP13,ELOF1,SRPK2,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,ZNF680,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,GEMIN5,PAF1,GATA6,TRMT5,CC2D1B,MKL2,PQBP1,CRCP,ZNF397,ZC3H8,NOCT,DMTF1,MTCH1,EMSY,TNRC6A,TAF1,ZCCHC8,PAX2,DPF2,MED13L,SMG7,PCSK7,DDIT4,ELL,ZNF354A,BUD31,NRIP1,POLR1E,CPSF3L,ZNF629,VOPP1,ZNF234,TRA2A,XPO5,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,CORIN,POP1,MYBBP1A,BICD1,INTS5,RRAGA,CDKAL1,ZFP90,TBL1X,AGO3,NR2C2AP,ZBTB24,TCF12,ASH1L,SMARCA4,PBX1,DHX35,SBDS,ZSCAN5A,FARSA,RRN3,MPHOSPH10,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,TSPAN14,UTP4,HTRA2,MAML3,NARS2,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,METTL2A,MRRF,METTL15,POU2F1,ATXN1,DKC1,PUSL1,WARS,BATF3,IKZF4,DUS3L,ADNP,HNRNPR,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,DISP1,NFRKB,BRD9,TSPAN5,SMG1,DNAJC2,SUPT6H,PPHLN1,ATF7IP,IGF2BP2,MED18,GFM2,MRPS11,CTNNBL1,ERI3,FBL,DMRT1,PKNOX1,RPS6KB2,ARNTL2,PPP1R9B,MSX1,KDM5B,ZNF821,TEAD1,PSPC1,KDM5A,ZNF324B,SCMH1,MARS,MEN1,EIF5B,ZNF407,SYMPK,TARS,ZNF221,RERE,ZNF708,VPS37B,ZRANB2,NCBP2,POLR1C,NFKBIB |
| 2.146e-22 | -49.89 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 15548 | 2126 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,SLC48A1,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.146e-22 | -49.89 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 15548 | 2126 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,AMBRA1,NOS1AP,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,SLC48A1,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,WDR26,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.146e-22 | -49.89 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 15548 | 2126 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,SLC48A1,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.146e-22 | -49.89 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 15548 | 2126 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,NDUFAF2,SLC48A1,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.317e-22 | -49.82 | classic | COSMIC cancer mutations | classic | 15549 | 2126 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,SLC48A1,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 3.149e-22 | -49.51 | medulla | COSMIC cancer mutations | medulla | 15553 | 2126 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,EIF4A2,CPT1A,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,NDUFAF2,SLC48A1,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 4.377e-22 | -49.18 | organic cyclic compound binding | molecular function | GO:0097159 | 5837 | 968 | 16491 | 2164 |
ASCC1,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,HLTF,NT5C3A,ZNF44,SYNJ1,PABPC4,ZNF37A,NEK6,SREBF2,IKZF5,ZFHX3,NSRP1,SYN2,THAP4,PDS5B,ZNF148,KDM5C,HRG,SRRM2,ZNRD1,FTSJ3,CDK6,HMBOX1,EIF4E3,NRAS,RNMT,GNL3,NFIA,KIF15,KRBOX4,RFX2,WDHD1,ABCC2,MCM2,RBM28,TMSB4X,ZNF197,DDX3X,AHNAK,ZNF266,BRCA2,RAD18,BDH2,RIOK1,DIRAS1,RUNX1,FIP1L1,ZNF532,MEF2C,CARS,BANP,EP400,TRIP6,SLK,KHDRBS1,TRIO,SIRT7,PIK3R4,PARN,YARS2,ABCA7,RBM20,DDX56,EIF2S2,DHX37,APLF,MCM5,ALKBH8,ZNF326,NOC3L,MRPL21,PRMT5,ZNF518B,MAP3K12,PABPC1,SERBP1,MYB,NOM1,HMGCR,ZNF675,GATAD2B,GTF2H3,MYO10,ZNF587,PRDM16,ARID5B,EIF4A2,IDH3G,TYW1,ZNF512B,RYR2,USP10,IMPDH2,MBNL2,ONECUT2,ABCF1,ZNF655,ZNF783,DYNC1H1,TSR1,GTF2A1,NME7,RPL28,TRAP1,LEMD3,CDK9,ZNF160,GPN1,CNOT6,WDR33,SRP14,SDSL,DNM3,MAP2K5,ABCA3,ZNF516,TRERF1,DDX18,NPAS2,ATP6V1A,PDK4,ACTR3,DDR2,MYH9,ISG20L2,TUBB6,SAFB2,ZMAT2,CBWD5,MCM9,HSPA1A,RPP30,ZBED2,PRKD3,ABCA12,ACD,ERI1,ZKSCAN1,CLCN6,NT5C,MSH4,PEG10,PXK,ZC3H3,LSM10,PMS1,KMT2D,GARS,ZNF480,EIF3J,NPM3,LGALS1,MEF2D,DSP,FKBP3,MAT2A,FGFR1,PES1,TAF2,ZFAND3,HIPK2,ARL13B,HOXA3,RPS6KB1,CENPBD1,FUS,ZBTB11,RAB30,HMGA2,ZNF786,XPC,SF3A3,JMJD6,IP6K2,BHLHE40,ZNF691,MBNL1,KRI1,TTLL11,SNW1,POLR3D,CBWD6,GATC,SUV39H2,NOP16,PTGS1,ZNF710,FBXL19,ACTR3B,SAMD4A,RPL22L1,SOX6,HNRNPM,DIS3L2,FAM98A,DDX24,POLK,ZC3H18,LDHA,R3HDM2,PPIP5K2,ZNF467,UBE2K,FOXC1,DDX49,UBC,ANXA1,RPA1,OXSR1,TRIB3,TOE1,ETFDH,NSD1,RARS,SRCAP,BAZ2B,PXDN,POLE2,ARID3B,ACOX1,AEN,GPATCH11,GPATCH4,CYP24A1,RBM33,TRIM16,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,SCAF8,HNRNPLL,MAP2K3,ABL2,SRSF2,PHF5A,DHX33,TRMU,XRCC2,HKR1,UBAP2L,ZNF85,RAN,POLE3,ZNF3,ETV1,TMPO,SF3A1,METTL1,CHD9,ZNF124,SLC3A2,ATF4,AEBP2,ABCC4,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,CDK4,KATNAL1,HSPA5,TSN,NOL6,BRCA1,ZNF91,LSG1,MLLT10,KIF16B,PEX1,DYRK1B,HPRT1,ZNF622,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,ARL4A,E2F4,RAD51B,PRPF4,DLX2,TSEN2,MAGI1,SEPHS2,XYLB,CTU2,SARS,TTN,MCM6,FOXO1,CLK1,MEX3A,HSD17B10,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,C1orf52,RLF,DNAH1,ARID1B,RNF40,SUB1,MLX,ZNF358,ABCA5,MBD2,VPS72,PDE10A,SYNJ2,ALDH18A1,GMDS,NT5E,WARS2,CAMKK2,PAXBP1,BCS1L,UTP15,OBSCN,MEX3B,ZNFX1,SUPT5H,CYB5B,ACOXL,NR2F1,TCF7L2,PGD,PRPF40B,SYNCRIP,PALB2,DNAH17,IRAK2,TBPL1,SIL1,ZNF430,DTD1,DDX10,BRSK2,PRKAR2A,BCCIP,SART1,PAPD4,SUCLG1,ARID2,RBFOX2,GPR143,RIPK1,RSL1D1,ZNF83,SSBP2,ZNF709,TIGD1,PELP1,DDX60L,URB1,ZNF121,KDM1A,DENR,METTL16,CAD,ZBTB21,NRF1,DUS4L,DNAJB6,IKBKB,MYH15,ETF1,ZFP37,CORO1A,AHCYL1,CTC1,SKIV2L,WDR36,TUBA1A,AKAP8L,DDX41,NARS,GLTSCR2,RAB7A,VIM,ARL5B,ZNF251,PUM3,EIF3H,USP36,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,ZNF18,SEPT5,EIF2B3,ZNF589,ZNF507,DMGDH,NIFK,MINK1,MCM10,MIF4GD,AUH,MAP3K13,RFX1,AGO2,ARFIP2,MAP1S,APRT,VARS,ZNF346,RBM19,CSNK1A1,FOXP1,RMI1,POGZ,HIST2H2AB,ZNF594,FAM50A,NDUFV1,ANXA7,ZNF561,IFIT5,HIST2H3D,DDX31,POLR1B,PCK2,TRNP1,SMARCAD1,FOXN3,ZNF654,ABCF2,TEX14,DHX34,TOP3A,HIST1H4J,EXOG,RHOT2,PIK3CB,POLR3A,ZRANB3,MKX,TPD52L2,NOL10,SRBD1,TAF4,SET,TBX3,CSRNP1,MSH3,EIF2S1,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,RPS6KC1,KIF1B,ZNF292,POLB,DDX19A,PRKCA,RAC3,GABPB2,AARS,UBR5,MGA,RPS16,SUCLG2,ME1,CHD2,DPH6,MEIS3,TRMT10A,ZNF646,DDN,ACADS,SNU13,SETD1B,OSBP2,NR6A1,NOL8,TCEB3,CUX1,HIST1H2BL,SON,DENND4A,DDX60,MAK16,CLNS1A,OSBPL1A,GNAI1,GZF1,DOT1L,SKIL,CCNT1,LSM14A,LUC7L3,ZNF81,HIC2,DNAH2,RFXAP,ZNF598,ZMAT3,NMD3,PRPF38B,WDR75,IFT57,DROSHA,EGR1,PRPF31,ANKRD17,LARS2,ZHX3,AK6,CENPB,GTF2IRD1,CCDC47,PRPF39,TGFBR2,PDCD5,CHD5,IGF2BP3,FKBP1A,PRKCE,HR,PI4KB,ZNF586,NOVA2,SCAF1,MYC,GTF3C3,IGF2BP1,CNOT4,PRPS1,TERF2,SCAF11,ADARB1,SIK3,DDX28,EXOSC2,RREB1,PRIM2,PCCA,POLA1,RAPGEF4,RAP1B,ARID1A,MTR,ZNF850,ARIH2,PHF6,ATP9B,ZNF425,CAT,ASCC3,EPRS,NSF,HIF1A,SPEN,SRP68,ZBTB12,D2HGDH,RIOK3,ZCCHC6,PURB,SQLE,C7orf50,NCOR1,SMYD3,MAP2K4,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,HFM1,KIAA0232,OLA1,SPATS2L,FOSL2,PABPC1L,LTB4R,HNRNPA3,FLNB,PDE3A,PAIP2,NOP56,TERF2IP,PHC2,CHD7,NUBPL,FLAD1,DECR1,ZNF827,PUS3,ASNS,KDM2A,UCHL5,GLYR1,SSBP1,CMPK1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,RFC4,ZCCHC14,BRD4,RFC3,GON4L,PDK1,MTIF2,KIAA1586,GNL1,SATB2,GALK2,PNN,POLG2,STK10,DHX57,SNCA,ZBTB25,VDR,DNTTIP1,MSX2,CAMK2D,SMARCC1,G6PD,DNAJA3,ZNF236,H2AFX,TRMT2A,CBWD1,MDN1,ANXA2,PDCD11,NOLC1,XRCC4,TROVE2,VWA8,SSH2,NOSTRIN,NCOR2,BRAF,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,FARS2,KIF5C,RCAN1,MYNN,RTN4,MLH1,OPA1,NOL3,RPS6KA5,GIGYF2,FOXO3,DCTPP1,ZNF239,ABL1,ZNF483,FTCDNL1,PTRF,PHYKPL,HARS2,UPF2,RDX,CELF1,EXOSC4,DYNC2H1,YBX3,LARP4B,MAP3K14,NT5M,NAV3,CLK2,PFKFB4,TSHZ1,TTLL5,APEX1,TBRG4,BMS1,PTK2,APTX,OASL,KLF6,GUF1,MMAA,NOP58,POLR2A,ZFP62,FBXO21,DDX50,ZNF155,IREB2,HELZ,HNRNPH3,ORC5,ATM,APAF1,ADK,DDIT3,KAT6A,STK4,ZNF76,MVK,EIF3C,UBN1,ATRX,RARS2,KIF5A,CERS5,TRPM6,ZNF107,BCOR,SIRT2,STK33,SNAPC4,EDC3,MRPS30,SMARCB1,SRPRB,RAP1A,CMSS1,YLPM1,JAZF1,MYH3,RELB,GPATCH1,ZEB1,POLR3B,SLC27A5,YARS,OGG1,LONP1,TRIP13,PRKACB,CARM1,TIMM50,SRPK2,ZBTB17,DEAF1,TNK2,ZNF195,SIRT6,ZNF680,ITPA,KSR2,CAV1,MTHFD1L,SGK2,ZSCAN2,SOX4,KMT2C,TIMM44,YTHDF2,GEMIN5,RHOU,UBTF,EIF4ENIF1,GATA6,HLCS,DNAJC1,CC2D1B,FAM114A2,PQBP1,CRCP,ABCC3,EME1,ZC3H8,ZNF397,NOCT,DMTF1,TNRC6A,AK2,ZCCHC8,RHOBTB1,TAF1,PAX2,DPF2,PHGDH,TOX4,RNF141,ZNF354A,ATXN2,BANF1,CCDC124,NRIP1,ZCCHC7,N4BP2,POLR1E,MTHFD1,ZNF629,MSI2,HBG2,ZNF234,PDE4A,TRA2A,XPO5,ZBED4,TBXAS1,WBSCR22,ZFP14,LIG4,PSMA1,PRDM1,EIF2A,AGAP1,DNAH14,UBE2E1,POP1,UBAP2,MYBBP1A,ATAD5,FSCN1,FDPS,RRAGA,HK2,SLC16A1,ZFP90,TBL1X,TBCK,AGO3,ZBTB24,TCF12,ASH1L,MYO7A,SMARCA4,PBX1,SPATS2,DHX35,SBDS,ZSCAN5A,RIOK2,MIEF1,ZC3H13,FARSA,RRN3,MPHOSPH10,CAMTA2,NVL,CBR4,RPS6KL1,ZNF142,FHIT,CPSF3,MET,ZNF460,UTP4,NARS2,ACSL5,PTBP2,TFCP2,PARP2,SFSWAP,GRHL3,R3HDM1,ATXN1,POU2F1,ATP8B2,DKC1,PUSL1,RAB10,S100A16,BATF3,WARS,TPK1,RAD54B,DUS3L,IKZF4,ADNP,HNRNPR,COPS5,ZNF557,ARNTL,CEBPZ,SLC25A11,FKBP5,SRFBP1,HEATR1,NFRKB,BRD9,SMG1,DNAJC2,BCKDK,TNIK,DNAJA4,SUPT6H,ARL15,CAMK1,PDE4B,NSUN6,H2AFJ,DBF4,TKFC,PPHLN1,IGF2BP2,ENOX1,PIP4K2A,GFM2,MFHAS1,MRPS11,PRKCH,GART,STC2,SHMT2,ERI3,FBL,DMRT1,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,KDM6B,ARNTL2,MSX1,KDM5B,GPHN,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,SCMH1,ZNF324B,MARS,PDE2A,MEN1,PEAK1,EIF5B,ZNF407,TARS,RERE,MFN2,ZNF221,CTIF,HSPA1B,ZNF708,GADD45A,ZRANB2,NCBP2,MBD6,POLR1C,ZAK,HRH1 |
| 5.777e-22 | -48.90 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 8129 | 1255 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,CNTNAP3,DCP1B,MRPL10,NAT10,TUBE1,SBF2,CCNL2,SLC6A8,LPAR3,SKI,PDZD2,ZFHX3,THAP4,AP1M1,MAD1L1,SRRM2,CCDC57,HMBOX1,NRAS,LIMA1,AP4B1,KIF15,WDHD1,SHISA5,ABCC2,SLC9A5,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,MPV17,RIOK1,RUNX1,ZNF532,SLC25A26,TMEM63C,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,WDR60,CCDC88C,PPA1,SAMD3,MYB,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,STAG1,ALG6,KCNQ3,ARID5B,TYW1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,IRS1,DYNC1H1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,KIAA0196,PDLIM5,ARHGAP10,SDSL,RAB11FIP4,C16orf45,VTI1A,DDR2,CD99L2,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,CD96,SPG21,TBC1D22A,SETD5,WAC,MSH4,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,FAM171A2,PCNXL2,DSP,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,CAMKMT,RPS6KB1,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,RNASEH2B,SNW1,TAF3,CFDP1,UNC13A,ANXA5,LTN1,FBXL19,ACTR3B,C15orf41,SAMD4A,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,MTMR1,RBM33,WDR13,SLC25A21,FAM13A,SCAF8,MAP2K3,SRSF2,METTL8,TRIML2,SLC25A23,FAM184A,VPS13B,DSC3,PPARG,CDK4,ANK2,LAMA2,KCNH2,DLST,LSG1,CXADR,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CLK1,ITFG1,NKD2,MAPK8IP3,FAN1,ARID1B,RNFT2,CEP290,MBD2,NDRG4,VAPB,CCDC167,CTR9,WNT16,PNPLA3,LRSAM1,SNX29,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,CYB5B,TCF7L2,TBC1D2,GRIK4,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,NTSR1,RIPK1,SSBP2,RADIL,SEMA6A,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,JAG1,NUP133,CCDC40,MYH15,AHCYL1,KDM3B,SOBP,AKAP8L,ANKRD33B,NHSL1,EIF3H,EXO1,ATG7,INTS9,EIF2B3,PARD3,DMGDH,ESCO1,AUH,RFX1,RBM19,FOXP1,POGZ,ANKRD54,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,PALLD,EXOG,SMPDL3B,CDH24,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,RBM26,TAF12,XPO6,KIF1B,LMBRD2,ZNF292,GYG1,PRKCA,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,CHD2,SPAG6,ACADS,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,SON,DDX60,CLNS1A,TMEM206,PLCXD2,GNAI1,OSBPL1A,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,NRP1,TNFRSF10D,WDR66,BLMH,SPOCK3,SPOCK2,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,ST6GAL1,DLGAP4,TATDN3,MTUS1,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,FDFT1,EXOSC2,PRIM2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CPT1C,HS2ST1,VMA21,SYT17,KIAA0232,TMEM104,PLEK2,PTPRG,PABPC1L,DECR1,PPID,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,C1orf228,PREX1,LRRC8A,SATB2,MARCH6,MEGF11,SETD7,ERC1,SNCA,BAZ1A,CAMK2D,SMARCC1,LARGE,IFT140,SLC4A7,TRAF3,MID1,SSH2,BRAF,B4GALT5,FARS2,RCAN1,OPA1,INPP1,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,CLK2,TMC7,FER1L5,TTLL5,PSAT1,ZFYVE1,AGPAT4,PACS1,SLC23A2,RETSAT,DDX50,ORC5,ATM,SVIL,APAF1,ADK,IMMP2L,LETM1,LYRM4,ATRX,RARS2,SLC52A3,SLC30A7,DST,CNIH3,JAZF1,MYH3,ZEB1,GPATCH1,B3GNTL1,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,FBXW4,SESN2,SKAP2,ARRDC3,TFPI,VWCE,MINA,KSR2,COTL1,MTHFD1L,SGK2,KMT2C,TIMM44,CCDC3,EIF4ENIF1,HLCS,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,DCAF5,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,QSER1,EVPL,NAMPT,ELL,HVCN1,ZNF354A,ISPD,ZCCHC7,LRP3,ATP6V0D1,AKAP11,HSD17B14,MTHFD1,PPAT,ELOVL6,XPO5,ELP3,JMJD1C,ZFP14,EIF2A,CORIN,SYT1,AGAP1,UBE2E1,EXOC6,POP1,SYCP2L,BICD1,KIAA0355,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,PDE9A,DMXL2,FEZ2,PSTPIP2,TNXB,SMARCA4,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,RIOK2,ZC3H13,RRN3,NVL,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,MAML3,NARS2,ANTXR2,MRRF,DKC1,UBR4,ARMC4,KPNA3,HNRNPR,ZNF557,CEBPZ,ARNTL,DUSP19,FKBP5,TMEM101,RNF130,SMG1,TMCC1,DNAJC2,BCKDK,CAMK1,DYM,CMTM8,PDE4B,VPS45,WDR26,IGF2BP2,SEMA3E,SOGA1,ENOX1,PIP4K2A,FAM49A,MFHAS1,GFM2,BMP6,PEX7,STC2,DCTN4,LDLRAD3,ERI3,RPS6KB2,TOP1,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,SULT4A1,SCFD2,ASAP3,PDE2A,TMEM187,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,ZSWIM6,ASCC1,CACNA1H,CSPP1,HLTF,NUP160,NOS1AP,AMBRA1,PCDH7,TOM1L1,NEK6,SREBF2,NSRP1,SYN2,RABGAP1L,FAAH2,RASSF3,PDS5B,ZNF148,HRG,AVEN,CNTNAP3B,CDK6,PTPRM,GNL3,AKAP12,PLEKHM3,C10orf76,RBM28,ZNF266,HERC2,EP400,NHS,RSF1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,INTS7,ZNF326,ANP32B,AGL,MAP3K12,FMNL2,GTF2H3,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,SMARCD3,ONECUT2,MBNL2,EVI5,CPT1A,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,CNOT6,WDR33,MB21D2,COG5,SPRED2,ZNF516,DNM3,ABCA3,TRERF1,DDX18,BTBD2,NPAS2,ATP6V1A,PDK4,ACTR3,MYH9,NECAP1,SAFB2,EEA1,STAM,PRKD3,BCAS2,ABCA12,FMNL1,MALL,GARS,FAM111B,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,CDC16,IQCH,PEMT,HIPK2,WDR7,BRCC3,ANKS1A,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,XPC,SESTD1,TRAK1,WDR37,JMJD6,AKT1S1,BHLHE40,RSRC1,MBNL1,KRI1,TADA3,PVRL3,SOX6,DIS3L2,NUDC,C21orf58,DDHD1,FBXO17,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FAM126B,UBE2K,PDE3B,CASC1,RPA1,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,PTPN4,SLCO5A1,GPAM,PSAP,IGBP1,DOCK6,ANAPC4,CORO2B,POLR1A,TFIP11,PPARGC1B,HECTD3,CSNK2A1,RNF43,TTI1,COX10,SEC16A,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,CDC37,SF3A1,TMPO,FLNC,METTL1,CHD9,SLC3A2,ABCC4,SKIV2L2,HARS,KATNAL1,GDPD1,MED27,GMFB,FLVCR1,MGST1,KIF16B,PEX1,GLS,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,STX8,LRRC28,ZFP36L1,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,GTF2H1,ALDH18A1,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,UTP15,WDR25,SUPT5H,VAC14,NR2F1,PWP1,SYNCRIP,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,TESC,PRKAR2A,KCTD7,LPCAT2,UBR1,FSIP2,DNAJB6,ARMC5,CYB5D1,ZDHHC6,IKBKB,HIBCH,CORO1A,AKNAD1,PRMT3,SEC24A,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,TMEM123,SLC35F2,AKAP13,NUP214,BTBD11,SMAD3,RANBP2,RBBP8,TIMM17A,CLEC16A,ZNF333,ABHD3,ITGA2,TSSC1,ZNF18,PPIL3,PKIB,UNC13D,MIF4GD,MAP3K13,FAM46B,C14orf159,ZNF346,CSNK1A1,BZW2,IQGAP2,PTPN2,NDUFV1,ANXA7,CWC27,PRICKLE2,DDX31,CD44,HSD17B12,ADAMTSL3,ZMYM5,TEX14,RAP1GDS1,PEAR1,C11orf49,GPNMB,RHOT2,TMEM175,PIK3CB,CHCHD6,ARMC3,CENPP,MKX,TPD52L2,C20orf196,SRBD1,GPC2,GLG1,EIF2S1,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,PRKAB2,TNFRSF21,ENAH,IKBIP,AARS,UBR5,MGA,VPS52,RNF111,ME1,CEP135,TBC1D8,DPF3,SLC38A6,SETD1B,NR6A1,ALDH1L2,NOL8,CUX1,SEMA3F,SAP30BP,SKIL,HSDL2,FAM122C,VPS13D,GREB1L,DNAH2,SEMA3C,ZNF598,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,CCDC53,ZHX3,ANKRD17,OPHN1,GTF2IRD1,PID1,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,ZNF586,TSPAN2,ASAP1,COPS3,SLC16A9,SAMD13,GTF3C3,IGF2BP1,LPCAT1,ADARB1,SCAF11,SIK3,SYNGAP1,AOC2,KIAA0586,TTYH2,PTPN12,PLCB1,ARIH2,LYRM7,EPRS,KIDINS220,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,TBKBP1,TRPM2,LIN28B,RWDD1,RIBC2,URB2,HFM1,SPRYD7,NDUFB5,OLA1,SPATS2L,FOSL2,PDE3A,PHC2,CHD7,ZNF827,SHC1,KDM2A,UCHL5,GLYR1,KMT2A,NAA35,ATP6AP1L,ZCCHC14,MPP6,PDK1,MTIF2,WDPCP,KIAA1586,GALK2,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,YIPF2,ZNF236,ALKBH1,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MON2,LIAS,MLH1,IKBKAP,REEP5,FOXO3,NEDD4,ZNF483,RGS17,PTRF,LRP2BP,NISCH,PMPCA,COPS7B,RDX,UPF2,NT5M,PLEKHG4,MBTPS2,FAM120B,WDFY3,FZD3,APTX,NOP58,FBXO21,KLHL22,ZDHHC11,HELZ,STX18,MYOM2,BRWD3,STK4,LRRC41,SLC43A1,SLC37A3,PHF3,UBN1,NF1,PTPRA,KIF5A,FANCD2,TRPM6,PLOD1,ANKRD18A,SLC29A1,BCOR,STK33,AHCYL2,EDC3,SMARCB1,ZNF804A,RTN1,ANAPC1,THADA,ZNHIT6,ATG3,ANAPC10,RELB,POLR3B,PCOLCE2,OGG1,PRKACB,TRIM14,ZBTB17,LAMA4,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,GPCPD1,HDAC8,ZSCAN2,SERGEF,PAF1,RHOU,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,SUFU,DNAJC1,MKL2,BBIP1,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,VIPR1,CHST11,PIGN,FN1,TAF1,SEC24D,ALG8,MED13L,PHGDH,CMTM3,RHBDD1,DDIT4,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,GLTP,NRIP1,POLR1E,CPSF3L,VOPP1,WWC1,C11orf65,PRDM1,C19orf70,DNAH14,UBAP2,ATAD5,MYBBP1A,SDCCAG8,HK2,EXOC4,KIAA1328,PDSS2,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,MYO7A,CSTA,UBTD2,GBF1,BRE,CCDC50,LYPLAL1,RPS6KL1,CPSF3,MET,HN1,TMLHE,ACSL5,COL5A2,PTBP2,FAM172A,TFCP2,SFSWAP,NLN,R3HDM1,ATP8B2,C1orf174,RAD54B,WARS,TPK1,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,TSPAN5,TNIK,SULT1C2,C17orf80,NSUN6,CLSTN2,CCDC7,PPP1R1C,SFI1,HDDC2,MAN1A1,PRKCH,CTNNBL1,DSG2,TTC17,UTS2,DMRT1,MARS,PHACTR2,LENG8,MEN1,ZNF407,NAPEPLD,SYMPK,MFN2,RERE,ALG5,MPP7,CUL2,PREPL,ZAK,MMP16,ARHGAP27,SLC16A10 |
| 1.170e-21 | -48.20 | RNA binding | molecular function | GO:0003723 | 1575 | 336 | 16491 | 2164 |
ASCC1,THOC5,DCP1B,DDX19A,AARS2,MRPL10,NAT10,HLTF,SYNJ1,UBR5,AARS,PABPC4,RPS16,NSRP1,CHD2,TRMT10A,SRRM2,FTSJ3,SNU13,EIF4E3,SETD1B,RNMT,GNL3,NOL8,WDHD1,SON,DDX60,RBM28,TMSB4X,MAK16,CLNS1A,DDX3X,AHNAK,CCNT1,LSM14A,LUC7L3,FIP1L1,ZNF598,NMD3,ZMAT3,MEF2C,CARS,PRPF38B,WDR75,DROSHA,TRIP6,PRPF31,ANKRD17,KHDRBS1,CCDC47,PRPF39,PARN,YARS2,IGF2BP3,RBM20,DDX56,EIF2S2,DHX37,NOVA2,SCAF1,ALKBH8,ZNF326,NOC3L,IGF2BP1,MRPL21,CNOT4,PABPC1,SERBP1,NOM1,ADARB1,SCAF11,GTF2H3,DDX28,EXOSC2,EIF4A2,USP10,IMPDH2,MBNL2,ABCF1,PHF6,DYNC1H1,ASCC3,EPRS,TSR1,RPL28,TRAP1,CDK9,SPEN,SRP68,ZCCHC6,PURB,CNOT6,C7orf50,WDR33,SRP14,PTCD2,LIN28B,DDX18,MYH9,ISG20L2,SPATS2L,PABPC1L,SAFB2,ZMAT2,HNRNPA3,FLNB,PAIP2,NOP56,RPP30,PUS3,ERI1,UCHL5,SSBP1,PEG10,SERPINH1,LSM10,EIF3J,NPM3,MTIF2,LGALS1,PNN,DSP,FKBP3,DHX57,PES1,TRMT2A,FUS,ANXA2,PDCD11,NOLC1,TROVE2,UTP14A,NFX1,SF3A3,FARS2,JMJD6,RTN4,NOL3,GIGYF2,MBNL1,KRI1,ZNF239,SNW1,PTRF,NOP16,HARS2,UPF2,RDX,CELF1,EXOSC4,YBX3,LARP4B,SAMD4A,RPL22L1,HNRNPM,DIS3L2,FAM98A,APEX1,DDX24,ZC3H18,TBRG4,BMS1,R3HDM2,APTX,OASL,DDX49,NOP58,UBC,POLR2A,ANXA1,RARS,DDX50,IREB2,HELZ,HNRNPH3,ADK,GPATCH4,RBM33,EIF3C,RARS2,PPARGC1B,HNRNPLL,SCAF8,EDC3,MRPS30,CMSS1,SRSF2,PHF5A,YLPM1,DHX33,TRMU,UBAP2L,RAN,YARS,LONP1,TIMM50,SF3A1,SRPK2,METTL1,SLC3A2,SKIV2L2,BAZ2A,TSN,NOL6,BRCA1,KMT2C,YTHDF2,GEMIN5,UBTF,ZNF622,EIF4ENIF1,CHD3,EEFSEC,PRPF4,DLX2,ZC3H8,NOCT,TNRC6A,CTU2,SARS,ZCCHC8,HSD17B10,MEX3A,ZFP36L1,C1orf52,RNF40,SUB1,ATXN2,MBD2,CCDC124,SYNJ2,ALDH18A1,ZCCHC7,MSI2,TRA2A,XPO5,WBSCR22,UTP15,PSMA1,ZNFX1,MEX3B,EIF2A,SUPT5H,POP1,PRPF40B,UBAP2,MYBBP1A,SYNCRIP,FSCN1,FDPS,DDX10,AGO3,BCCIP,SART1,SUCLG1,RBFOX2,RSL1D1,SPATS2,DHX35,URB1,DDX60L,PELP1,SBDS,ZC3H13,DENR,METTL16,FARSA,MPHOSPH10,NVL,ETF1,CORO1A,AHCYL1,CPSF3,UTP4,SKIV2L,WDR36,DDX41,PTBP2,AKAP8L,GLTSCR2,SFSWAP,ATXN1,R3HDM1,VIM,DKC1,S100A16,USP36,EIF3H,PUM3,PUSL1,RANBP2,DUS3L,HNRNPR,COPS5,CEBPZ,SLC25A11,SRFBP1,PUS1,HEATR1,EIF2B3,SMG1,DMGDH,DNAJC2,NIFK,AUH,MIF4GD,SUPT6H,AGO2,NSUN6,PPHLN1,IGF2BP2,RBM19,ZNF346,GFM2,MRPS11,FAM50A,ANXA7,IFIT5,DDX31,ERI3,FBL,TOP1,PSPC1,DHX34,MARS,HIST1H4J,EIF5B,CTIF,TPD52L2,NOL10,SRBD1,EIF2S1,NCBP2,ZRANB2,RBM26,ZAK |
| 6.758e-21 | -46.44 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 11169 | 1629 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,ZNF44,ABHD6,LPAR3,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,LIMA1,UPP1,EHMT1,AP4B1,KIF15,C11orf80,WDHD1,C5AR1,SHISA5,ABCC2,SLC9A5,ZNF197,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,BDH2,MPV17,RIOK1,RUNX1,VASH2,ZNF532,SLC25A26,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,PDCD7,PARN,CDC73,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,MYB,NOM1,RABEPK,LRRC20,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ARID5B,TYW1,USP10,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,USP46,RDH11,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,SDSL,RAB11FIP4,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,FAM122B,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,UBL5,RPGRIP1L,CD96,SPG21,ZSWIM7,ACD,TBC1D22A,WAC,CLCN6,C16orf58,INTS12,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,PI4KAP2,EIF3J,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,SLC35D1,NUDT15,DSP,VPS53,MAT2A,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,CEP170,METTL2B,CATSPERG,BAG1,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,TRIM22,RNASEH2B,PSMF1,SNW1,PSMG4,TAF3,NOP16,CFDP1,UNC13A,ANXA5,LTN1,ZNF710,ACTR3B,C15orf41,SAMD4A,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,BMP4,SORCS2,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,AMPD3,ECM1,PHF5A,COPS4,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DSC3,MIOS,PPARG,ANK2,HSPA5,TSN,SUMO3,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,BSN,HPRT1,TCF7L1,LSS,INSIG1,CHD3,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,BEND6,USP15,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,IFT43,SETD2,HAUS6,OBSCN,METTL22,CYB5B,ACOXL,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,NTSR1,SLC2A1,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,SEMA6A,PAG1,DDX60L,URB1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,AKAP8L,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,EXO1,LMBR1L,ATG7,INTS9,MED20,EIF2B3,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,POGZ,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,FOXN3,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,POLR3A,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,TMEM219,RBM26,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCSH,GYG1,PRKCA,LRP5L,GABPB2,LPIN1,EXOC1,S100A10,ZFYVE28,SPAG6,CSGALNACT2,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,ZDHHC14,DENND4A,SON,TMEM206,PLCXD2,GNAI1,OSBPL1A,SPOP,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,NRP1,TNFRSF10D,WDR66,BLMH,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,C9orf78,JUP,LARS2,ST6GAL1,DLGAP4,TATDN3,C1orf50,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,PIGG,CNOT4,FDFT1,EXOSC2,IFNGR2,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,SLC26A11,MTR,PHF6,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,FLNB,IGSF1,DECR1,SLX4,PPID,LPIN2,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,SETD7,ERC1,SNCA,ZBTB25,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,LARGE,IFT140,SLC4A7,CBWD1,TRAF3,SETD6,MID1,SSH2,BRAF,B4GALT5,FARS2,RCAN1,DNAJC22,OPA1,INPP1,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,FER1L5,TTLL5,PSAT1,ZFYVE1,AGPAT4,TMEM126A,PACS1,BMS1,KLF6,GUF1,SLC23A2,DDX50,ZNF155,IREB2,COQ9,ORC5,ATM,SVIL,APAF1,ADK,IPO4,IMMP2L,ZNF76,LETM1,LYRM4,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,MYH3,ZEB1,GPATCH1,B3GNTL1,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,FBXW4,SESN2,SKAP2,ITPA,ARRDC3,TFPI,VWCE,MINA,KSR2,COTL1,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,CCDC3,EIF4ENIF1,HLCS,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,ZC3H8,DCAF5,FBXO45,RHOBTB1,VTA1,STXBP6,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,ISPD,CCDC124,ZCCHC7,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZFP14,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,PFDN2,TBL1X,FNBP1L,TBCK,PDE9A,N4BP2L2,DMXL2,TCF12,FEZ2,PSTPIP2,TMEM183A,PIGH,SMARCA4,TBCCD1,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,KCTD11,MPHOSPH10,NVL,CBR4,SNTG2,FHIT,ITGAX,VCL,TMEM120B,GNG5,AUP1,NARS2,ANTXR2,PRAME,ATXN1,POU2F1,MRRF,EDEM2,UBR4,BATF3,ARMC4,KPNA3,HNRNPR,ZNF557,WDR73,ARNTL,DUSP19,FKBP5,RNF130,NFRKB,SMG1,TMEM33,TMCC1,DNAJC2,SUPT6H,DYM,CMTM8,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,STC2,DCTN4,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,WDR74,CACNA1H,CSPP1,HLTF,NUP160,NOS1AP,AMBRA1,PABPC4,TOM1L1,PCDH7,C1orf159,SREBF2,NSRP1,SYN2,RABGAP1L,FAAH2,RASSF3,C12orf76,PDS5B,ZNF148,HRG,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,GNL3,RFX2,AKAP12,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,SUPT4H1,FIS1,HERC2,TNNC1,EP400,TRIP6,KHDRBS1,NHS,PLA2G12A,RSF1,SLC1A1,ABCA7,SLC39A11,SH2B3,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,ZNF326,NOC3L,ANP32B,COQ3,AGL,MAP3K12,TOMM34,FMNL2,SERBP1,BDNF,GTF2H3,COL17A1,RB1CC1,PRDM16,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,EEA1,STAM,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,GSTA4,CEP63,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,LGALS1,ADAM32,TTC28,PDE8B,HLA-DMA,GNG2,PES1,IQCH,CDC16,PEMT,HIPK2,WDR7,BRCC3,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,XPC,SESTD1,TRAK1,ID2,SF3A3,WDR37,AKT1S1,RSRC1,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,ARHGAP1,HNRNPM,SOX6,ULBP1,DIS3L2,DDHD1,FAM98A,FBXO17,FGF9,ERICH1,CLYBL,ARHGAP39,FRA10AC1,MRPS10,FAM126B,UBE2K,PDE3B,CASC1,RPA1,KISS1R,ETFDH,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,ARID3B,SLCO5A1,PTPN4,SLC25A19,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,ANAPC4,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,PPCDC,UBAP2L,ZNF85,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,FLNC,METTL1,CHD9,ZNF124,SLC3A2,HARS,SKIV2L2,KATNAL1,GDPD1,MED27,GMFB,NOL6,ATG12,ZNF91,FLVCR1,MGST1,CCDC28B,PEX1,KIF16B,GLS,MSRA,ZNF622,TP53BP1,EEFSEC,TECPR2,CCDC146,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,C16orf52,MEX3A,TRIM15,BARX2,RLF,DOPEY1,RNF40,KIAA1958,ABCA5,SAMD11,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,UTP15,WDR25,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,ITPRIPL1,SYNCRIP,PALB2,SNAP23,DNAH17,ZNF430,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,PRKAR2A,RNF114,CYLD,LPCAT2,GPR143,RSL1D1,LPCAT3,DENR,CAD,DUS4L,UBR1,FSIP2,DNAJB6,ZDHHC6,C15orf40,ETF1,HIBCH,ANO8,ZFP37,AKNAD1,PRMT3,CTC1,CASP10,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,MANBAL,TMEM123,SLC35F2,AKAP13,NUP214,BTBD11,SMAD3,RANBP2,RBBP8,ZNF333,CLEC16A,ABHD3,ITGA2,TSSC1,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,UNC13D,MAP3K13,FAM46B,C14orf159,MAP1S,ZNF346,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,CWC27,PRICKLE2,DDX31,SELT,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,ADAT2,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,POLB,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,ENAH,IKBIP,UBR5,AARS,MGA,GIPR,RPS16,VPS52,PAK1IP1,RNF111,ME1,PRADC1,MEIS3,CEP135,FUT11,SEH1L,DPF3,SLC38A6,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,TXN2,FAM118A,ZNF598,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ENTPD5,ASAP1,COPS3,SLC16A9,SAMD13,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,SYNGAP1,AOC2,KIAA0586,TTYH2,PTPN12,RABAC1,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,SRRD,NSF,PMEPA1,ZZEF1,D2HGDH,RIOK3,PEX13,UMPS,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,TRPM2,CCDC58,LIN28B,RWDD1,URB2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,FOSL2,SLC25A44,TRIM66,PDE3A,PAIP2,PHC2,CHD7,TERF2IP,ZNF827,PUS3,KDM2A,UCHL5,GLYR1,SSBP1,PNPLA4,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,RFC4,MPP6,PDK1,SFXN4,MTIF2,WDPCP,DLG4,PNN,MED16,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,HTR7,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,CA11,UTP14A,TTC27,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,ZNF483,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,RDX,NLGN3,LARP4B,NT5M,MBTPS2,FAM120B,PFKFB4,WDFY3,C19orf43,FZD3,APTX,MMAA,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,STX18,RNF138,MYOM2,BRWD3,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,SNAPC4,AHCYL2,EDC3,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,ANAPC10,RELB,IPP,JOSD1,POLR3B,PCOLCE2,NDUFA6,TRIM14,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,ZSCAN2,TCTN1,SERGEF,CDHR3,CHAF1A,TMEM132B,GEMIN5,PAF1,EPN2,SUFU,GATA6,DNAJC1,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,RELL2,CHST11,PIGN,SEC24D,TAF1,DPF2,ALG8,MED13L,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,GLTP,NRIP1,N4BP2,CPSF3L,VOPP1,KRT20,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,SDCCAG8,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,TMEM14C,TMLHE,HN1,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,RAB10,TPK1,RAD54B,WARS,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SLC25A11,DISP1,SCARB1,HEATR1,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,H2AFJ,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,DSG2,TANK,KDELC1,TTC17,UTS2,DMRT1,MSX1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,ZNF330,CUL2,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10 |
| 8.566e-21 | -46.21 | diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | diffuse_large_B_cell_lymphoma | 4353 | 741 | 17775 | 2278 |
ADAM19,CDCP1,THOC5,CACNA1H,SBF2,HLTF,NUP160,NOS1AP,TOM1L1,PCDH7,PDZD2,MMP7,ZFHX3,NSRP1,SYN2,RABGAP1L,FAAH2,C12orf76,MAD1L1,PDS5B,WIZ,HRG,FXN,AVEN,SRRM2,NRAS,WLS,PTPRM,EXOC6B,KIF15,AKAP12,MCL1,PLEKHM3,SLC9A5,STOML2,BRCA2,RAD18,RUNX1,SLC25A26,ZNF532,MEF2C,CARS,HERC2,EP400,TRIO,NHS,PIK3R4,RSF1,CDC73,ABCA7,SLC39A11,CHN1,DDX56,UBE3A,CNST,INTS7,CCDC88C,AGL,PABPC1,FMNL2,PPA1,SAMD3,RABEPK,LRRC20,FADS1,BDNF,STAG1,ALG6,KCNQ3,MYO10,RB1CC1,PRDM16,ARID5B,EIF4A2,RYR2,USP10,ST6GALNAC3,CPT1A,TRIM37,EVI5,MBNL2,ONECUT2,USP46,NCDN,DYNC1H1,VPS13C,LRP1B,TASP1,NME7,LEMD3,CCDC85B,CNOT6,PDLIM5,MB21D2,ARHGAP10,COG5,ABCA3,DNM3,ZNF516,ATP6V1A,NPAS2,PAFAH1B1,BTBD2,VTI1A,DDR2,MYH9,ST3GAL6,LCLAT1,STAM,RPGRIP1L,PRKD3,CD96,ABCA12,TBC1D22A,WAC,MMP14,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,EIF3J,ARHGEF10,ADAM32,PCNXL2,KCNH3,TTC28,DSP,MAT2A,FGFR1,ZFAND3,FBXL5,ARHGAP21,IQCH,CDC16,ASTN2,NSMCE2,HIPK2,PEMT,CAMKMT,WDR7,ZBTB11,ANKS1A,YEATS2,TRIM36,LRCH1,MORC2,COMMD10,HMGA2,SHQ1,SESTD1,XRRA1,ID2,ATG2B,TRIM22,RSRC1,MBNL1,PSMF1,KRI1,TAF3,CFDP1,UNC13A,ZNF710,SOX6,HNRNPM,SPTAN1,VPS37A,CLYBL,POLK,ZC4H2,ARHGAP39,ZC3H18,FRA10AC1,NXN,RSBN1,CCDC113,ZNF467,PPIP5K2,PDE3B,CASC1,DDX49,OXSR1,ETFDH,NSD1,BAZ2B,PXDN,NME1-NME2,HERC1,SLCO5A1,SLC25A19,PSAP,SORCS2,MTMR1,CORO2B,KDM4C,CYP24A1,MFGE8,SLC25A21,FAM13A,TTI1,TMEM132A,SCAF8,PHKA1,ANKRD11,METTL8,UBAP2L,PTPRK,VPS13B,FLNC,DSC3,DBN1,CHD9,ATF4,ABCC4,MIOS,PPARG,KATNAL1,ANK2,MED27,PSMG1,LAMA2,FLVCR1,ZNF91,HPRT1,TCF7L1,MSRA,TP53BP1,CHD3,EEFSEC,TECPR2,TNFRSF1A,RAD51B,ADAM9,PRPF4,MAGI1,BEND6,USP15,SARS,FOXO1,STX8,ITFG1,LRRC28,FAN1,HSD17B10,MAPK8IP3,BARX2,ZFP36L1,ARID1B,DNAH1,DOPEY1,CEP290,VAPB,TIMELESS,SYNJ2,GMDS,LRSAM1,SNX29,TRAPPC9,CRADD,IFT43,SETD2,WDR25,SUPT5H,CYB5B,VAC14,PGD,PWP1,PRPF40B,GRIK4,SNX24,ZNF430,SIL1,DTD1,ARHGAP12,GGT7,DDX10,SH3PXD2A,USP7,NDUFA5,SART1,OLFM2,ARID2,LPCAT2,NTSR1,RSL1D1,LPCAT3,SSBP2,DENND3,RADIL,PPP1R9A,SEMA6A,URB1,DDX60L,PLXNB1,CAD,ZNF608,ANKRD13A,JAG1,NUP133,UBR1,DNAJB6,FGGY,IKBKB,ANKRD24,CCDC40,MYH15,ETF1,HIBCH,AKNAD1,CTC1,KDM3B,SKIV2L,SOBP,SEC24A,TLCD1,PCGF3,EVL,SSFA2,NARS,THSD4,ANKRD33B,MANBAL,TMEM123,AKAP13,NUP214,ARL5B,BTBD11,SMAD3,RBBP8,SIX5,KLF4,TIMM17A,CLEC16A,ITGA2,ATG7,TSSC1,INTS9,PRRT3,MED20,PARD3,PKIB,DMGDH,AUH,RBM19,ZNF346,FOXP1,ADH5,CWC27,TMEM161A,PRICKLE2,CPNE7,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,PEAR1,ARHGEF12,C11orf49,PALLD,CHCHD6,PIK3CB,ARMC3,SMPDL3B,CENPP,TPD52L2,NOL10,SRBD1,DSC2,BCAS3,FNTB,RBM26,RPS6KC1,KIF1B,MIPOL1,CGN,LUZP1,PRDX6,ENAH,PRKCA,UBR5,MGA,EXOC1,ZFYVE28,ME1,PRADC1,SPAG6,NR6A1,ALDH1L2,EYA3,CUX1,VSNL1,PLCXD2,OSBPL1A,GNAI1,TRRAP,HSDL2,SH3RF1,ARL6IP5,LUC7L3,HSPBAP1,VPS13D,SEMA3C,GREB1L,DNAH2,WDR66,TNFRSF10D,NRP1,RFXAP,ZMAT3,NMD3,PTPN14,EFNB2,WDR75,DROSHA,CELSR1,ANKRD17,LARS2,CENPB,OPHN1,GTF2IRD1,PID1,CD226,MTUS1,ANXA10,PRKCE,NAV1,ZNF586,ASAP1,MYC,PIGG,SLC16A9,SAMD13,SIK3,PRIM2,IFNGR2,PCCA,RAP1GAP2,PTPN12,ARID1A,PLCB1,EHBP1,MTR,ARIH2,ATP9B,ZNF425,ASCC3,HIF1A,VCAN,SPEN,ZZEF1,MED15,ZCCHC6,SQLE,PEX13,C7orf50,NCOR1,MACROD1,MAP2K4,HS2ST1,RTTN,TRPM2,BIRC6,SPATA2L,URB2,HFM1,KIAA0232,OLA1,TMEM104,PTPRG,PABPC1L,FLNB,PDE3A,IGSF1,PHC2,CHD7,KDM2A,PPID,VGF,DTNBP1,SHF,CMPK1,KMT2A,ATP6AP1L,CDK12,NAA35,BRD4,WDPCP,SATB2,SETD7,TBC1D16,STK10,ERC1,SNCA,VDR,BAZ1A,CAMK2D,SMARCC1,ZNF236,LARGE,ALKBH1,TRAF3,MDN1,PDCD11,NOLC1,MID1,SSH2,BRAF,TTC27,NFX1,FARS2,RCAN1,MON2,IKBKAP,NEDD4,ABL1,NEBL,RDX,CELF1,DYNC2H1,MBTPS2,NAV3,TSHZ1,TTLL5,ZFYVE1,WDFY3,AGPAT4,FZD3,KCNMA1,PACS1,SLC23A2,ZDHHC11,STX18,RNF138,ATM,SVIL,MYOM2,APAF1,BRWD3,ADK,STK4,IMMP2L,LETM1,FEM1C,NF1,ATRX,FANCD2,PLOD1,AHCYL2,SLC30A7,SMARCB1,RTN1,ZNF804A,DST,CNIH3,JAZF1,JOSD1,SLC27A5,CEP128,TIMM50,LAMA4,DTNB,GPM6A,FBXW4,SKAP2,ZNF680,CMIP,VWCE,TMEM216,KSR2,HDAC8,MTHFD1L,PITPNB,KMT2C,TCTN1,SERGEF,YTHDF2,CHAF1A,CCDC3,TMEM132B,EPN2,HLCS,DNAJC1,RLTPR,CSMD3,ASB3,CLU,GALNT10,DMTF1,MTCH1,SLC12A7,DCTN3,CHST11,PIGN,FN1,RHOBTB1,SEC24D,ZCCHC8,TAF1,STXBP6,DPF2,MED13L,SMG7,EVPL,RHBDD1,ELL,SIPA1L3,HVCN1,ZNF354A,ATXN2,ISPD,SEMA3D,ZCCHC7,NRIP1,LRP3,KRT20,ELOVL6,ELP3,ZBED4,EIF2A,PRDM1,CORIN,SYT1,AGAP1,HERPUD1,DNAH14,UBE2E1,EXOC6,POP1,SYCP2L,UBAP2,BICD1,KIAA0355,FAT1,EXOC4,CDKAL1,TMEM117,KIAA1328,PDSS2,PDE9A,DMXL2,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,COBLL1,ST7L,SLC9B2,PIBF1,UBTD2,GBF1,DHX35,BRE,SOCS1,CCDC50,NVL,PPFIBP1,SNTG2,ZNF142,FHIT,ADCK4,MET,VCL,TMEM120B,C6orf89,NARS2,COL5A2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,DKC1,TPK1,BATF3,ARMC4,ZC3H12A,KPNA3,HNRNPR,SRFBP1,RNF130,HEATR1,TSPAN5,SMG1,TMCC1,TNIK,DYM,CMTM8,PDE4B,DBF4,NSUN6,CLSTN2,IGF2BP2,SEMA3E,CCDC7,SOGA1,MFHAS1,BMP6,PIP4K2A,HDDC2,SFI1,MAN1A1,PRKCH,DCTN4,DSG2,TANK,STC2,SHMT2,TTC17,LDLRAD3,SLC25A1,TOP1,KDM6B,DNMBP,FGF2,CRIM1,PSPC1,METTL23,SCFD2,ASAP3,ZNF324B,PHACTR2,ZNF407,NAALADL2,TARS,RERE,CTIF,ZNF708,DAGLB,WDR35,MPP7,AGTPBP1,ZRANB2,ZAK,MMP16,ZSWIM6,CTXN1 |
| 1.852e-20 | -45.44 | macromolecule metabolic process | biological process | GO:0043170 | 7395 | 1160 | 16441 | 2138 |
PTP4A1,GGT1,ADAM19,THOC5,DPH1,DCP1B,AARS2,MRPL10,CCNL2,ZNF44,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,EHMT1,NFIA,WDHD1,C5AR1,MCM2,ZNF197,SSU72,RAD18,RIOK1,RUNX1,ZNF532,BANP,TRIO,PIK3R4,PDCD7,PARN,CDC73,RBM20,UBE3A,DHX37,APLF,MED24,GEMIN4,MRPL21,PABPC1,PPA1,MYB,ZNF675,GATAD2B,ALG6,WDR61,STAG1,ZNF587,ARID5B,TYW1,ATAT1,USP10,ST6GALNAC3,TRIM37,SRA1,USP46,IRS1,KPNA1,RPL28,EHMT2,CCDC85B,SRP14,C18orf25,GTF2H2C,DDR2,ISG20L2,NUP43,ST3GAL6,ZMAT2,MCM9,UBL5,ZSWIM7,ACD,WAC,MMP14,INTS12,MSH4,PXK,TRMT12,ZC3H3,PMS1,KMT2D,ZNF480,EIF3J,KCNH3,MEF2D,SLC35D1,DSP,FBXL5,KDM4B,ELP2,NSMCE2,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,COMMD10,HMGA2,GAS6,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,TAF3,LTN1,ZNF710,FBXL19,RPL22L1,SPTAN1,VPS37A,DDX24,USP42,UBC,MRPL36,ANXA1,OXSR1,NSD1,SRCAP,HERC1,SRD5A3,AEN,BMP4,MTMR1,CUL7,TRIM16,SCAF8,HNRNPLL,MAP2K3,SRSF2,PHF5A,COPS4,HKR1,TRIML2,ZNF3,ZMYM2,RBCK1,AEBP2,ATF4,PPARG,CDK4,HSPA5,TSN,SUMO3,KCNH2,MLLT10,DYRK1B,TCF7L1,CHD3,E2F4,DPP4,ADAM9,PRPF4,PPP3CC,TSEN2,BEND6,USP15,CTU2,FOXO1,CLK1,PRSS3,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,CTR9,ICE2,LRSAM1,WARS2,USP49,SETD2,OBSCN,TCF7L2,PRPF40B,CASS4,DTD1,GGT7,PTP4A2,DDX10,BCCIP,USP7,SART1,MPI,ID1,PAPD4,ARID2,RPS29,LAGE3,RIPK1,DENND3,TNKS1BP1,ZNF121,NRF1,JAG1,NUP133,GRIN2C,AHCYL1,SPIDR,PRPF19,KDM3B,RAB7A,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,ZNF507,NIFK,ESCO1,MINK1,MCM10,HM13,RFX1,AGO2,VARS,FOXP1,ADH5,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,TOP3A,EXOG,POLR3A,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,GABPB2,LPIN1,EXOC1,DPH6,CHD2,CSGALNACT2,ZNF646,ZDHHC14,DENND4A,SON,CLNS1A,SPOP,DOT1L,GZF1,TRRAP,CCNT1,SH3RF1,NSMCE1,LUC7L3,CFD,HIC2,XPNPEP1,BLMH,BMI1,SPOCK2,SPOCK3,PRPF38B,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,HR,USPL1,SCAF1,MYC,PIGG,CNOT4,EXOSC2,ANAPC13,RREB1,PRIM2,ARID1A,NELFA,ZNF850,PHF6,SEC31A,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,DPEP1,NCOR1,CNDP2,SMYD3,HS2ST1,ZNF254,BIRC6,POP5,PTPRG,PABPC1L,HNRNPA3,RING1,NOP56,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,TTC3,CDK12,CASP8AP2,SAP30,BRD4,PCMT1,SATB2,MARCH6,SETD7,ERC1,SERP1,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,G6PD,MBTD1,LARGE,FTSJ1,TRAF3,SETD6,XRCC4,SSH2,BRAF,B4GALT5,FARS2,RPS6KA5,GIGYF2,SFR1,ABL1,ELP5,CELF1,DYNC2H1,CLK2,PXN,TTLL5,APEX1,KLF6,GUF1,ZFP62,DDX50,ZNF155,ORC5,ATM,APAF1,DDIT3,KAT6A,IMMP2L,ZNF76,PIGM,EIF3C,ATRX,KMT2E,RARS2,PPIL1,SLC30A7,PCYOX1L,CNIH3,KANSL1,JAZF1,ANAPC11,GPATCH1,ZEB1,SLC35C2,YARS,CARM1,SRPK2,DEAF1,TNK2,FBXW4,SESN2,ZNF195,SIRT6,TFPI,MINA,KSR2,SGK2,KMT2C,ST3GAL5,TIMM44,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,ZCCHC8,UBXN1,PCSK7,SMG7,EVPL,TIMM10,RNF141,ELL,P3H1,ZNF354A,ISPD,TENM3,ATP6V0D1,ZNF629,ZNF234,TRA2A,XPO5,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,CORIN,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,CDKAL1,PFDN2,TBL1X,TBCK,AGO3,NR2C2AP,TCF12,DLL4,CEMIP,TNXB,PIGH,SMARCA4,PBX1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,FHIT,ADCK4,UTP4,AUP1,MAML3,NARS2,PRAME,GRHL3,METTL2A,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,DUS3L,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,MED18,IGF2BP2,ATF7IP,GFM2,SEC24C,ERI3,FBL,PKNOX1,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,KDM5B,GPHN,FGF2,ZNF821,PSPC1,KDM5A,SCMH1,ZNF324B,PEAK1,EIF5B,ZNF221,CTIF,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,ASCC1,WDR74,HLTF,NUP160,PABPC4,TOM1L1,SREBF2,NEK6,PMAIP1,NSRP1,FNIP2,ZNF148,FXN,CDK6,PTPRM,RFX2,MSRB3,DCUN1D5,RBM28,STOML2,DDX3X,SUPT4H1,BRCA2,ZNF266,FIP1L1,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,SLK,SIRT7,RSF1,YARS2,ABCA7,DDX56,EIF2S2,INTS7,MCM5,ALKBH8,ZNF326,ANP32B,PRMT5,AGL,MAP3K12,ZNF518B,PEA15,TIMM8B,GTF2H3,COL17A1,RB1CC1,PRDM16,EIF4A2,ZNF512B,SMARCD3,ONECUT2,MBNL2,ABCF1,ZNF655,ZNF783,TASP1,CLASRP,GTF2A1,CDK9,ZNF160,CNOT6,SENP3,WDR33,ZNF516,ABCA3,MAP2K5,TRERF1,DDX18,NPAS2,PDK4,MYH9,TUBB6,SAFB2,HSPA1A,RPP30,PRKD3,BCAS2,ZKSCAN1,ERI1,ATRIP,LSM10,PERP,GARS,STAMBP,NPM3,ATF7IP2,ADAM32,FKBP3,FGFR1,PES1,TAF2,CDC16,HIPK2,FUS,BRCC3,ZBTB11,YEATS2,TRIM36,ZNF786,XPC,TRAK1,SF3A3,ID2,JMJD6,TGFB2,BHLHE40,MBNL1,RSRC1,POM121,TADA3,NPRL2,SUV39H2,GATC,SOX6,LYPLA2,HNRNPM,DIS3L2,FGF9,POLK,MRPS10,ZNF467,UBE2K,DDX49,FOXC1,RPA1,TRIB3,RARS,TOE1,BAZ2B,POLE2,STX1A,ARID3B,PTPN4,ANAPC4,KDM4C,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,SEC16A,BIRC2,ABL2,DHX33,PHKA1,TRMU,XRCC2,POLE3,RAN,ZNF85,ETV1,SF3A1,PTPRK,METTL1,CHD9,GCNT2,ZNF124,ZNF414,BAZ2A,HARS,SKIV2L2,MED27,NOL6,GMFB,COL4A3BP,ATG12,BRCA1,ZNF91,KIF16B,GLS,MSRA,TP53BP1,EEFSEC,PER1,SOCS4,RAD51B,DLX2,CHMP4C,TTN,SARS,PGPEP1,MCM6,HSD17B10,HES6,BARX2,ZFP36L1,RLF,RNF40,TRMT13,PPIL2,TIMELESS,GTF2H1,SYNJ2,NT5E,CAMKK2,TRAPPC9,CRADD,PAXBP1,TLE3,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PWP1,ATXN7,SPAG9,SYNCRIP,PALB2,IRAK2,TBPL1,ZNF430,HMBS,BRSK2,NAPA,TESC,RNF114,CYLD,RBFOX2,PPP2R2A,ZNF83,RNF24,ZNF709,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,ZBTB21,DUS4L,UBR1,ZDHHC6,IKBKB,ZFP37,ETF1,RNF2,PRMT3,CASP10,CTC1,SKIV2L,KAT8,SEC24A,WDR36,PCGF3,TUBA1A,DDX41,NARS,THSD4,AKAP13,ENC1,NUP214,USP36,SMAD3,RANBP2,RBBP8,SIX5,TIMM17A,ZNF333,ZNF436,PUS1,ZNF18,PPIL3,MAP3K13,CSNK1A1,RMI1,ZNF594,PTPN2,ZNF561,CWC27,HIST2H3D,DDX31,SELT,FBXO31,CD44,ADAMTSL3,GINS3,ZNF654,ZMYM5,DHX34,TEX14,HIST1H4J,NEU1,POLR3G,ZRANB3,GPC2,ZBTB8OS,ADAT2,SET,MSH3,EIF2S1,MYRF,RPS6KC1,POLB,MYCBP2,PRKAB2,DDX19A,PLRG1,ADAMTS6,AARS,UBR5,MGA,RPS16,RNF111,TRMT10A,MEIS3,FUT11,SEH1L,SNU13,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,DESI1,SAP30BP,SKIL,ZNF81,CCNB1IP1,PTPN14,WDR75,IFT57,EGR1,DROSHA,ZHX3,GTF2IRD1,CCDC47,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,ENTPD5,ZNF586,COPS3,GTF3C3,IGF2BP1,TERF2,SCAF11,ADARB1,USE1,DDX28,SIK3,SYNGAP1,POLA1,PTPN12,ARIH2,ZNF425,EPRS,NSF,UBAP1,D2HGDH,ZBTB12,RIOK3,PURB,MACROD1,MAP2K4,ZFHX2,PTCD2,LIN28B,ZBTB37,HFM1,KLHL18,FOSL2,TERF2IP,PHC2,CHD7,ZNF827,PUS3,KDM2A,SHC1,UCHL5,SSBP1,SERPINH1,KMT2A,RFC4,RFC3,PDK1,MTIF2,DLG4,MED16,PNN,POLG2,STK10,DHX57,VDR,DNAJA3,ZNF236,H2AFX,TRMT2A,ALKBH1,ACP1,NOLC1,PDCD11,TROVE2,NCOR2,UTP14A,C10orf2,TCF3,ZNF280C,NFX1,MYNN,LIAS,MLH1,NOL3,IKBKAP,FOXO3,MAD2L2,NEDD4,ZNF239,ZNF483,COMMD9,PTRF,PMPCA,COPS7B,UPF2,HARS2,PHYKPL,EXOSC4,MAP3K14,YBX3,NT5M,MBTPS2,FAM120B,TSHZ1,TBRG4,APTX,PTK2,NOP58,POLR2A,YIF1A,FBXO21,KLHL22,COL26A1,ZDHHC11,HNRNPH3,RNF138,PGAM5,LRRC41,STK4,PHF3,FEM1C,NF1,PTPRA,TRPM6,FANCD2,RCHY1,ZNF107,PLOD1,SIRT2,BCOR,STK33,SNAPC4,EDC3,SMARCB1,MRPS30,SRPRB,ANAPC1,YLPM1,LONRF2,ATG3,ANAPC10,HYAL1,IPP,RELB,JOSD1,POLR3B,GALNT18,OGG1,LONP1,PRKACB,TRIP13,TIMM50,ELOF1,ZBTB17,TRIM13,TXLNG,ZNF680,LVRN,HDAC8,CAV1,ZSCAN2,SOX4,TAF9B,CHAF1A,UBTF,GEMIN5,PAF1,UBE3D,SUFU,GATA6,TRMT5,MKL2,PQBP1,GALNT10,COPS6,ZNF397,NOCT,DMTF1,TNRC6A,EMSY,PIGN,CHST11,FN1,TAF1,SEC24D,PAX2,DPF2,ALG8,MED13L,RHBDD1,DDIT4,CEP164,ATXN2,BANF1,BUD31,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,ISG15,MYBBP1A,INTS5,EXOC4,RRAGA,ZFP90,ZBTB24,ASH1L,CSTA,ZSCAN5A,FARSA,BRE,LYPLAL1,CAMTA2,RPS6KL1,ZNF142,MET,CPSF3,TSPAN14,ZNF460,HTRA2,PTBP2,COL5A2,TFCP2,PARP2,SFSWAP,NLN,PUSL1,WARS,RAD54B,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,SH2D3A,DBF4,PPHLN1,MRPS11,MAN1A1,PRKCH,CTNNBL1,HAS3,DMRT1,MSX1,TEAD1,PSMC3IP,MARS,MEN1,ZNF407,SYMPK,TARS,RERE,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,PREPL,TATDN1,MMP16,ZAK |
| 1.358e-19 | -43.44 | nucleolus | cellular component | GO:0005730 | 836 | 199 | 17570 | 2233 |
WDR74,NF1,POLR1A,PLRG1,FANCD2,NAT10,HLTF,NLE1,CUTC,CIAPIN1,SMARCB1,ZFHX3,DHX33,JAZF1,PAK1IP1,RNF111,DPH6,CHD2,RAN,TRMT10A,ZNRD1,FTSJ3,SRPK2,METTL1,DEAF1,SNU13,RNMT,SKIV2L2,SIRT6,BAZ2A,CDK4,GNL3,NOL8,MED27,MINA,NOL6,RBM28,MAK16,CHAF1A,GZF1,UBTF,ZNF622,CCNT1,CHD3,ARL4A,EME1,TSEN2,TXN2,ZMAT3,NMD3,WDR75,DROSHA,PAX2,SIRT7,AK6,SMAD7,CRACR2A,PARN,DDX56,SUB1,DHX37,MYC,TIMELESS,GTF3C3,ANP32B,GEMIN4,NOC3L,NRIP1,ZCCHC7,POLR1E,NOM1,ADARB1,SCAF11,DDX28,EXOSC2,RREB1,MYO10,TRA2A,POLA1,HOMER2,ELP3,IDH3G,WBSCR22,UTP15,ZNF655,PHF6,PWP1,POP1,TSR1,ATXN7,MYBBP1A,SRP68,SENP3,PFDN2,WDR33,LIN28B,DDX18,URB2,OLA1,SMARCA4,RSL1D1,ISG20L2,SPATS2L,POP5,URB1,RPAIN,PELP1,SBDS,NOP56,RPP30,CHD7,RRN3,MPHOSPH10,BCAS2,KDM2A,PPID,NVL,ERI1,HIRIP3,TTC3,UTP4,C6orf89,CDK12,HN1,ACSL5,WDR36,GLTSCR2,PARP2,NPM3,ATF7IP2,SETD7,ENC1,DKC1,USP36,S100A16,PUM3,PES1,DNTTIP1,RBBP8,HNRNPR,PUS1,HEATR1,MDN1,PDCD11,NOLC1,NIFK,SHQ1,MIF4GD,MCM10,UTP14A,XPC,MRI1,NFX1,MAP1S,JMJD6,BHLHE40,IKBKAP,RBM19,NOL3,ZNF346,KRI1,ABL1,SURF2,NOP16,DDX31,EXOSC4,POLR1B,ERI3,LARP4B,FBL,PNMA1,HNRNPM,SNAPC5,TOP1,ARNTL2,DDX24,APEX1,PSPC1,KDM5A,BMS1,APTX,OASL,PIK3CB,NOP58,POLR2A,CENPP,TOE1,DDX50,NOL10,ACOX1,ZNF330,CUL2,BCAS3,AEN,RBPJ,MBD6,POLR1C,XPO6,KAT6A |
| 3.323e-19 | -42.55 | RNA processing | biological process | GO:0006396 | 758 | 187 | 16441 | 2138 |
THOC5,TFIP11,AARS2,PLRG1,PPIL1,NUP160,SCAF8,HNRNPLL,AARS,PABPC4,RPS16,SRSF2,PHF5A,NSRP1,DHX33,TRMU,GPATCH1,RAN,TRMT10A,SRRM2,FTSJ3,SEH1L,SRPK2,SF3A1,METTL1,SNU13,RNMT,SKIV2L2,NOL8,NOL6,WDHD1,SON,RBM28,CLNS1A,PAF1,GEMIN5,SSU72,TRMT5,LUC7L3,PQBP1,PRPF4,FIP1L1,TSEN2,NOCT,CTU2,PRPF38B,SARS,DROSHA,ZCCHC8,PRPF31,KHDRBS1,HSD17B10,PDCD7,PRPF39,CDC73,RBM20,DDX56,DHX37,INTS7,SCAF1,TRMT13,ALKBH8,BUD31,ZNF326,GTF2H1,GEMIN4,PRMT5,PABPC1,CPSF3L,SCAF11,ADARB1,GTF2H3,EXOSC2,USP49,TRA2A,ELP3,TYW1,WBSCR22,UTP15,SUPT5H,MBNL2,PRPF40B,POP1,EPRS,BICD1,SYNCRIP,CLASRP,SPEN,INTS5,ZCCHC6,CDKAL1,WDR33,AGO3,PTCD2,SART1,PAPD4,LIN28B,RBFOX2,LAGE3,NUP43,POP5,PABPC1L,ZMAT2,DHX35,UBL5,HNRNPA3,SBDS,NOP56,RPP30,METTL16,CHD7,MPHOSPH10,PUS3,BCAS2,DUS4L,NUP133,ERI1,INTS12,CPSF3,AHCYL1,TRMT12,UTP4,ZC3H3,LSM10,CDK12,PRPF19,WDR36,PTBP2,DDX41,SFSWAP,NPM3,METTL2A,METTL15,ATXN1,PNN,DKC1,NUP214,DHX57,PUSL1,PES1,SMAD3,RANBP2,DUS3L,HNRNPR,FTSJ1,INTS9,TRMT2A,SRFBP1,PUS1,HEATR1,FUS,PDCD11,NOLC1,PPIL3,METTL2B,UTP14A,SUPT6H,AGO2,SF3A3,FARS2,JMJD6,NOL3,RSRC1,MBNL1,POM121,MRPS11,SNW1,CTNNBL1,CWC27,CELF1,EXOSC4,ERI3,FBL,HNRNPM,DIS3L2,PPP1R9B,PSPC1,DHX34,SYMPK,NOP58,POLR2A,ZBTB8OS,ADAT2,HNRNPH3,ZRANB2,NCBP2,RBM26 |
| 9.058e-19 | -41.55 | NXF1 (nuclear RNA export factor 1) | protein interactions | 10482 | 1111 | 263 | 16036 | 2270 |
THOC5,DPH1,DDX19A,PRKCA,AARS,RABGAP1L,EMC8,KDM5C,AVEN,GDAP1,OSBP2,LIMA1,WLS,NOL8,DESI1,MSRB3,SEMA3F,MCL1,C10orf76,SON,FOXRED1,SAP30BP,SUPT4H1,AHNAK,LUC7L3,XPNPEP1,GREB1L,BMI1,SYNPO,DROSHA,SIRT7,DLGAP4,OPHN1,PIK3R4,FAM192A,LDOC1L,USPL1,TNPO3,SLC16A9,IGF2BP1,AGL,TOMM34,EXOSC2,ANAPC13,SIGMAR1,POLA1,EPS15L1,ARID1A,NELFA,MBNL2,CPT1A,MTR,DAGLA,SEC31A,ASCC3,EPRS,PDLIM1,EHMT2,SRRD,UBAP1,TRAP1,SURF1,SENP3,UMPS,SGSM3,PTCD2,MAP2K5,AMOTL1,TRERF1,ACTR3,UROD,TUBB6,RPGRIP1L,PAIP2,NOP56,FLAD1,DECR1,ZBED2,SHC1,BCAS2,SETD5,MRPS27,CMPK1,LSM10,ZC3H3,FAM111B,SFXN4,SNHG1,MEF2D,TBC1D16,STK10,PES1,CDC16,SMARCC1,ELP2,CAMKMT,KLHDC4,NOLC1,ZBTB11,YEATS2,BAG1,TMEM141,XRRA1,NFX1,FARS2,JMJD6,WDR37,MAD2L2,DCTPP1,COMMD9,SNW1,NPRL2,HARS2,FIRRE,HNRNPM,NUDC,PFKFB4,FAM98A,PXN,APEX1,DDX24,WDFY3,ZC3H18,MRPS10,ADSL,BMS1,UBE2K,UBC,POLR2A,ANXA1,INF2,ETFDH,FBXO21,HELZ,POLE2,HNRNPH3,SLC25A19,IPO4,KDM4C,LRRC41,SRM,ZNF76,MVK,TRIM16,GPBP1L1,NF1,POLR1A,TFIP11,CSNK2A1,SCAF8,PCYOX1L,ANAPC1,SRSF2,COPS4,MARVELD2,UBAP2L,POLE3,RAN,POLR3B,YARS,CDC37,SF3A1,CEP128,ATF4,TXLNG,ITPA,HARS,HSPA5,MINA,NOL6,SUMO3,NR2F1-AS1,CAV1,PITPNB,LSG1,GEMIN5,CHD3,TP53BP1,E2F4,EEFSEC,CRCP,GALNT10,MAGI1,USP15,EMSY,SEPHS2,PIGN,TAF1,UBXN1,ALG8,XPO7,NAMPT,RNF40,MLX,ATXN2,CTR9,ALDH18A1,NIPSNAP1,TRAPPC9,PAXBP1,TRA2A,XPO5,WWC1,OBSCN,ZNFX1,EIF2A,SUPT5H,CYB5B,PGD,KIAA0754,FDPS,FNBP1L,TCF12,TBCCD1,FAM210A,PUDP,PIBF1,URB1,SLC39A1,UBR1,PPFIBP1,ZDHHC6,ZNF142,CPSF3,AHCYL1,ZNF460,IPO11,PRPF19,ARHGAP17,DDX41,ANKRD33B,CA5B,DKC1,NUP214,UBR4,PUM3,S100A16,RANBP2,COPS5,USP11,ATXN7L2,SH2D3A,PDE4B,PPHLN1,LETMD1,RBM19,POGZ,FAM50A,ANXA7,SEC24C,LDLRAD3,FBL,RPS6KB2,ABCF2,RANGAP1,ARHGAP32,PDE2A,C8orf33,MFN2,TPD52L2,CDH24,SRBD1,CUL2 |
| 1.112e-18 | -41.34 | poly(A) RNA binding | molecular function | GO:0044822 | 1179 | 260 | 16491 | 2164 |
DCP1B,MRPL10,NAT10,HLTF,PABPC4,RPS16,NSRP1,CHD2,TRMT10A,SRRM2,FTSJ3,SNU13,GNL3,NOL8,SON,RBM28,TMSB4X,MAK16,CLNS1A,DDX3X,AHNAK,LSM14A,LUC7L3,FIP1L1,ZNF598,ZMAT3,NMD3,PRPF38B,WDR75,DROSHA,TRIP6,PRPF31,ANKRD17,KHDRBS1,CCDC47,PARN,YARS2,IGF2BP3,DDX56,EIF2S2,DHX37,NOVA2,ZNF326,NOC3L,IGF2BP1,MRPL21,CNOT4,PABPC1,SERBP1,NOM1,SCAF11,ADARB1,DDX28,EIF4A2,USP10,MBNL2,ABCF1,PHF6,DYNC1H1,ASCC3,TSR1,RPL28,TRAP1,SPEN,SRP68,ZCCHC6,PURB,C7orf50,WDR33,SRP14,PTCD2,LIN28B,DDX18,MYH9,ISG20L2,SPATS2L,SAFB2,HNRNPA3,FLNB,PAIP2,NOP56,RPP30,UCHL5,SSBP1,PEG10,SERPINH1,MTIF2,NPM3,LGALS1,PNN,DSP,FKBP3,DHX57,PES1,TRMT2A,ANXA2,FUS,PDCD11,NOLC1,UTP14A,NFX1,SF3A3,RTN4,GIGYF2,MBNL1,KRI1,SNW1,PTRF,NOP16,HARS2,RDX,CELF1,YBX3,LARP4B,SAMD4A,RPL22L1,HNRNPM,FAM98A,DDX24,APEX1,ZC3H18,TBRG4,BMS1,R3HDM2,OASL,NOP58,DDX49,UBC,POLR2A,DDX50,IREB2,HELZ,HNRNPH3,ADK,GPATCH4,EIF3C,RBM33,RARS2,HNRNPLL,EDC3,MRPS30,CMSS1,SRSF2,PHF5A,YLPM1,DHX33,UBAP2L,RAN,YARS,SF3A1,SRPK2,SLC3A2,SKIV2L2,TSN,NOL6,KMT2C,YTHDF2,GEMIN5,UBTF,ZNF622,EIF4ENIF1,CHD3,EEFSEC,ZC3H8,NOCT,TNRC6A,ZCCHC8,HSD17B10,MEX3A,ZFP36L1,C1orf52,RNF40,SUB1,ATXN2,MBD2,CCDC124,ALDH18A1,ZCCHC7,MSI2,TRA2A,XPO5,UTP15,WBSCR22,ZNFX1,MEX3B,SUPT5H,POP1,MYBBP1A,UBAP2,SYNCRIP,FSCN1,FDPS,DDX10,AGO3,BCCIP,SART1,SUCLG1,RBFOX2,RSL1D1,SPATS2,URB1,PELP1,DHX35,SBDS,ZC3H13,METTL16,FARSA,MPHOSPH10,NVL,ETF1,CORO1A,UTP4,WDR36,DDX41,PTBP2,AKAP8L,GLTSCR2,R3HDM1,DKC1,EIF3H,S100A16,USP36,PUM3,DUS3L,HNRNPR,CEBPZ,SLC25A11,SRFBP1,HEATR1,PUS1,SMG1,DMGDH,NIFK,DNAJC2,AUH,SUPT6H,AGO2,PPHLN1,IGF2BP2,ZNF346,RBM19,MRPS11,FAM50A,ANXA7,IFIT5,DDX31,FBL,ERI3,TOP1,PSPC1,DHX34,HIST1H4J,EIF5B,TPD52L2,NOL10,EIF2S1,RBM26,NCBP2,ZRANB2,ZAK |
| 4.319e-18 | -39.98 | SIRT7 (sirtuin 7) | protein interactions | 51547 | 659 | 176 | 16036 | 2270 |
CGN,MYCBP2,CUL7,PHF3,NF1,POLR1A,NAT10,PLOD1,CSNK2A1,SEC16A,NLE1,NUP160,UBR5,AARS,PABPC4,DST,ANAPC1,SRSF2,RPS16,YLPM1,UBAP2L,PDS5B,CHD2,SRRM2,FTSJ3,LONP1,SF3A1,FLNC,BAZ2A,SKIV2L2,GNL3,NOL6,HIST1H2BL,MTHFD1L,SON,RBM28,MAK16,STOML2,GEMIN5,UBTF,TRRAP,AHNAK,TP53BP1,HERC2,WDR75,MCM6,FN1,ZCCHC8,ANKRD17,RSF1,XPO7,PARN,IGF2BP3,DDX56,DHX37,MCM5,ATIC,GTF3C3,GEMIN4,NOC3L,ALDH18A1,PRMT5,PABPC1,SERBP1,SCAF11,POLA1,XPO5,UTP15,RNH1,IMPDH2,ARID1A,SUPT5H,ABCF1,POP1,DYNC1H1,PWP1,ASCC3,TSR1,MYBBP1A,SPAG9,SYNCRIP,FSCN1,SPEN,SRP68,ZCCHC6,DDX10,USP7,SART1,FAM208B,PCNT,BIRC6,DDX18,URB2,ACTR3,MYH9,SMARCA4,RSL1D1,AP1B1,TNKS1BP1,HNRNPA3,PELP1,URB1,KDM1A,FLNB,ZC3H13,CAD,CHD7,ASNS,MPHOSPH10,NUP133,NVL,GLYR1,SERPINH1,CPSF3,KMT2A,VCL,UTP4,SKIV2L,WDR36,NARS,GLTSCR2,PNN,NUP214,DSP,UBR4,PUM3,DHX57,WARS,PES1,RANBP2,SMARCC1,ADNP,CEBPZ,H2AFX,FUS,MDN1,HEATR1,USP11,NOLC1,ZBTB11,PDCD11,CEP170,NIFK,UTP14A,SUPT6H,IGF2BP2,SOGA1,IKBKAP,GIGYF2,POGZ,KRI1,SNW1,GART,SEC24C,DDX31,LARP4B,FBL,SPTAN1,TOP1,DDX24,ZC3H18,WDR18,BMS1,RANGAP1,OASL,EIF5B,SYMPK,NOP58,POLR2A,ANXA1,NSD1,NOL10,HELZ,ATM,PGAM5,IPO4 |
| 4.470e-18 | -39.95 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 853 | 199 | 17758 | 2279 |
WDR74,TUBE1,ENAH,SLC29A1,CHAC1,PRKCA,NUP160,SYNJ1,AARS,SLC30A7,IKZF5,PMAIP1,METTL8,ME1,CHD2,ZMYM2,OGG1,CDK6,PRKACB,SEH1L,CSGALNACT2,TIMM50,DBN1,SLC3A2,SESN2,RBCK1,ABCC4,ALDH1L2,GPCPD1,ARRDC3,ATOX1,PACRGL,MINA,MCL1,EFHC1,PEX1,SLC7A1,LSS,DNAJC1,TRMT5,ARL4A,CTAGE5,RIOK1,ZNF397,CCNB1IP1,NRP1,TNFRSF10D,FAM118A,DCAF5,LPP,CARS,WDR75,SARS,IFT57,CELSR1,EGR1,SEC24D,ITPRIP,C16orf52,FAN1,TATDN3,PHGDH,TIMM10,PDCD5,RHBDD1,DDIT4,NAMPT,SH2B3,C6orf48,SLC38A5,SLC7A11,GTF2H1,NOC3L,GMDS,FMNL2,RABEPK,SCAF11,IFRD1,WDR61,TRA2A,UTP15,TRAPPC6B,ARRDC4,MBNL2,PGD,TSR1,MTHFD2,KIAA0355,TRAP1,RIOK3,ZCCHC6,UMPS,TBL1X,WDR33,SH3PXD2A,C18orf25,N4BP2L2,USP7,TCF12,PPDPF,CYLD,MAP2K5,ST7L,SSBP2,FOSL2,CSTA,RPAIN,URB1,PAG1,NOP56,FARSA,JAG1,ASNS,CCDC50,LPIN2,SLC38A2,RNF2,MTHFD2L,PRMT3,SAP30,MAML3,SEC24A,GARS,TUBA1A,SFXN4,NPM3,PREX1,LGALS1,NLN,ATXN1,GNL1,AKAP13,NHSL1,SETD7,WARS,TPK1,ATP5D,BATF3,PLIN2,SLC39A14,KLF4,G6PD,HIPK2,ZNF436,FTSJ1,SCARB1,ZNF18,CENPBD1,NOLC1,PDCD11,MUTYH,KLHL24,VPS45,LETMD1,ID2,VARS,ZNF691,CSNK1A1,RPS6KA5,INPP1,NEDD4,TANK,STC2,SHMT2,DDX31,PCK2,ERRFI1,ERI3,FBL,ACTR3B,RPL22L1,KDM6B,PSAT1,ERICH1,WDFY3,FOXN3,ZMYM5,TPM4,FRA10AC1,MARS,PHACTR2,RANGAP1,APTX,C8orf33,EIF5B,TRIB3,NOL10,BAZ2B,GADD45A,ZNF330,SRD5A3,DNAJC12,MBD6,PGAM5,RPS6KC1,KIF1B,LMBRD2,STK4,ZSWIM6 |
| 4.523e-18 | -39.94 | cell part | cellular component | GO:0044464 | 15692 | 2104 | 17570 | 2233 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,WDR60,MED24,TNPO3,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,ZNF675,GATAD2B,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,CD96,SPG21,ACD,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,LRRC75A-AS1,KCNH3,MEF2D,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,RAPGEFL1,PTGS1,ZNF710,ACTR3B,PNMA1,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,MTMR1,TRIM16,FAM13A,HNRNPLL,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,FAN1,LAMTOR3,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,WNT16,LRSAM1,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,CASS4,GGT7,PTP4A2,USP7,ID1,SUCLG1,UPK3B,PAPD4,ARID2,NTSR1,SLC2A1,RADIL,PAG1,PPP1R9A,NUP133,CCDC40,MYH15,BCAP29,SPIDR,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,KIRREL2,TEX19,RAB7A,EIF3H,TJAP1,EXO1,IFT81,HSPB8,EIF2B3,MUTYH,PARD3,DMGDH,NIFK,MINK1,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,POLR1B,FOXN3,SMARCAD1,SLC35G1,TOP3A,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,NBEAL1,PRKCA,LPIN1,S100A10,SUCLG2,DPH6,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,SPOP,OSBPL1A,DOT1L,GZF1,DDAH2,CCNT1,LSM14A,SH3RF1,HSPBAP1,NSMCE1,ARL6IP5,CFD,HIC2,TNFRSF10D,BMI1,BLMH,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,CRACR2A,SSR4,TECTA,MYC,PIGG,EXOSC2,ANAPC13,PRIM2,RREB1,RDH10,RAPGEF4,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,NCOR1,BIRC6,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,RMDN3,CMPK1,ARL14EP,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,MBTD1,SLC4A7,TRAF3,TBXA2R,XRCC4,SETD6,VWA8,NOSTRIN,BRAF,RCAN1,INPP1,PHLDA2,SFR1,ABL1,NEBL,ELP5,SDCBP2,S100A14,NAV3,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,MINA,TMEM216,KSR2,MTHFD1L,SGK2,KMT2C,MPC1,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,EVPL,NAMPT,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,ZNF629,MSI2,HBG2,ZNF234,PPAT,TRA2A,JMJD1C,ELP3,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,CEMIP,PIGH,SMARCA4,ARSJ,PIBF1,SBDS,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,EDEM2,S100A16,ALAD,DUS3L,KPNA3,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,CRAMP1,RPS6KB2,MARCH9,ARNTL2,SLC6A16,DNMBP,KDM5B,GPHN,CRIM1,SULT4A1,ZNF324B,SCMH1,PEAK1,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,TRAPPC12,ASCC1,CACNA1H,CHAC1,NT5C3A,COA1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,HRG,LYRM5,AVEN,MSRB3,PLEKHM3,DCUN1D5,RBM28,TMSB4X,DDX3X,ZNF266,BRCA2,FIP1L1,MEF2C,LPP,ADGRE2,TNNC1,CLDN15,TRIP6,SLK,NHS,RSF1,CLINT1,DDX56,EIF2S2,SLC38A5,ALKBH8,NOC3L,CALN1,PRMT5,ZNF518B,AGL,COQ3,FMNL2,SERBP1,HMGCR,FADS1,MYO10,RB1CC1,EIF4A2,EVI5,CPT1A,MBNL2,ONECUT2,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,ADGRE5,CNOT6,WDR33,SPRED2,ABCA3,MAP2K5,NPAS2,ATP6V1A,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,YEATS2,ANKS1A,TRIM36,NOL4L,TGFB2,RSRC1,SUV39H2,TMSB10,ARHGAP1,HNRNPM,LYPLA2,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,GPAM,PSAP,IGBP1,DOCK6,NUDT22,CORO2B,KDM4C,BCAS4,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,RNF43,TMEM132A,COX10,BIRC2,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,TMPO,PTPRK,SF3A1,CDC37,FLNC,METTL1,CHD9,GCNT2,SKIV2L2,HARS,ZNF414,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,C2CD5,XYLB,SARS,TTN,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,TRAPPC6B,SUPT5H,NR2F1,PGD,PWP1,SPAG9,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,BRSK2,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,PELP1,RPAIN,CAD,ZBTB21,DUS4L,UBR1,FSIP2,ARMC5,IKBKB,ANO8,RNF2,HIBCH,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,AKAP13,ENC1,ARL5B,NUP214,PUM3,TMEM186,USP36,RBBP8,SLC30A3,CLEC16A,ITGA2,ZNF436,NFASC,ZNF18,SEPT5,PPIL3,ZNF589,MAP3K13,ARFIP2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,PRICKLE2,HIST2H3D,CD44,HSD17B12,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,NEU1,ARMC3,ZRANB3,MKX,POLR3G,CENPP,TPD52L2,ADAT2,GLG1,NDUFAF5,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,GIPR,RPS16,RNF111,ME1,TRMT10A,SEH1L,DDN,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,HSH2D,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,CCDC53,ANKRD17,OPHN1,PID1,TGFBR2,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,LYRM7,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,PTCD2,AMOTL1,TRPM2,CCDC58,LIN28B,OLA1,SPATS2L,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,RFC4,CFAP221,RFC3,WDPCP,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,TAMM41,DNAJA3,H2AFX,ACP1,MDN1,ANXA2,PDCD11,NCOR2,SCAMP3,CA11,C10orf2,ZNF280C,SLC25A12,MLH1,CEP126,LIAS,IKBKAP,NOL3,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,PHYKPL,UPF2,COPS7B,EXOSC4,YBX3,LARP4B,NT5M,TSHZ1,WDFY3,WDR18,PTK2,APTX,MMAA,ECH1,POLR2A,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,POLR3B,SLC27A5,GALNT18,OGG1,PRKACB,TRIM14,ELOF1,ZBTB17,TXLNG,CMIP,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,PAF1,RHOU,UBTF,EPN2,UBE3D,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,EMSY,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,CDIP1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,N4BP2,POLR1E,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,ZBTB24,ZNF706,MYO7A,FAM210A,SLC9B2,GBF1,ZSCAN5A,MIEF1,VPS18,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,MET,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,OXLD1,H2AFJ,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,ARHGAP26,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,EMC8,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,KRBOX4,NFIA,SLC9A5,ZNF197,RBSN,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RUNX1,TPM1,P2RY11,EPM2AIP1,PDCD7,CHN1,CNST,CCDC88C,MRPL21,RABEPK,NOM1,MYB,KCNQ3,STAG1,ALG6,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,SUGCT,GTF2H2C,DDR2,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZSWIM7,CLCN6,INTS12,MSH4,PXK,PEG10,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,CCNDBP1,NUDT15,DSP,SLC39A14,ARHGAP21,MISP,ELP2,KDM4B,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,UQCC1,CYP24A1,CUL7,AAMDC,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,PHF5A,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KCNH2,KRTCAP2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,DPP4,PRPF4,PPP3CC,BEND6,UQCC2,CLK1,SMAD7,MAPK8IP3,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,ICE2,PNPLA3,NIPSNAP1,IFT43,USP49,SETD2,HAUS6,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SLC52A2,BCCIP,MPI,SART1,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,KIZ,ESCO1,RFX1,AGO2,ESRG,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,PCSK6,TRNP1,AP4S1,ABCF2,FERMT2,RANGAP1,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBPJ,KIF1B,XPO6,LUZP1,GYG1,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,VSNL1,CAMSAP2,SUPT20H,DDX60,DENND4A,SON,GNAI1,TRRAP,LUC7L3,XPNPEP1,NRP1,NMD3,RFXAP,CADM4,JUP,CDC42EP2,LARS2,PRPF31,TATDN3,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,NOVA2,USPL1,CNOT4,PLEKHA2,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,NELFA,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,ZNF254,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,FLNB,RING1,NOP56,DECR1,PPID,LPIN2,MRPS27,SOCS6,TTC3,CASP8AP2,PCMT1,PREX1,SATB2,GNL1,MARCH6,MEGF11,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,RPS6KA5,DYNC2H1,CELF1,ERRFI1,CLK2,FER1L5,PSAT1,APEX1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,KAT6A,ZNF76,EIF3C,KMT2E,RARS2,DST,CNIH3,KANSL1,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,ARRDC3,TFPI,COTL1,PITPNB,ST3GAL5,CC2D1B,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,RHOBTB1,ZCCHC8,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,P3H1,ZNF354A,TENM3,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,TMEM117,SLC16A1,PFDN2,TBL1X,FNBP1L,N4BP2L2,AGO3,NR2C2AP,CHMP2A,SNX27,DLL4,PSTPIP2,TNXB,TBCCD1,PBX1,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,UTP4,AUP1,PRAME,GRHL3,POU2F1,MRRF,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,ARC,RNF130,SMG1,TMEM33,TMCC1,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,WDR26,IGF2BP2,ATF7IP,MED18,ENOX1,GFM2,BMP6,SCN1B,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,PPP1R9B,ZNF821,FGF2,PSPC1,KDM5A,ASAP3,METTL23,PDE2A,EIF5B,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,WIZ,ZNF148,FNIP2,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,HERC2,CARS,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,EMC10,PEA15,BDNF,GTF2H3,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,GTF2A1,CDK9,ZNF160,SENP3,COG5,ZNF516,DNM3,FAM208B,TRERF1,BTBD2,DDX18,ACTR3,PDK4,MYH9,NECAP1,TUBB6,SAFB2,EEA1,STAM,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,NPM3,ASUN,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,WDR7,FUS,BRCC3,LAMA5,ZNF786,SERINC5,INSIG2,XPC,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,NUDC,ULBP1,DIS3L2,FAM98A,FBXO17,CEP83,CLYBL,CEP295,MRPS10,R3HDM2,UBE2K,RPA1,RARS,TOE1,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,NREP,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,FAM206A,EEFSEC,PER1,TNFRSF1A,DLX2,CHMP4C,PGPEP1,MCM6,STX8,ITPRIP,HSD17B10,MEX3A,HES6,TRIM15,ZFP36L1,BARX2,RLF,DNAH1,PPIL2,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,PAXBP1,CRADD,TLE3,BCS1L,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,TMEM94,DNAJB6,ZDHHC6,HIRIP3,ZFP37,ETF1,AKNAD1,CORO1A,PRMT3,CASP10,SEC24A,SKIV2L,WDR36,DDX41,TUBA1A,NARS,CPOX,TMEM123,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,TIMM17A,ABHD3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,NDUFV1,SACS,CWC27,DDX31,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,TPM4,PEAR1,C11orf49,CHCHD6,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,MYRF,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,DDX19A,TMEM109,ENAH,IKBIP,UBR5,AARS,RAC3,MGA,VPS52,PAK1IP1,MEIS3,CEP135,FUT11,SLC38A6,DPF3,EYA3,GNG7,NOL8,CUX1,TCEB3,DESI1,SAP30BP,MAK16,SH3GL1,HSDL2,ZNF81,DNAH2,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,CELSR1,EGR1,ZHX3,AK6,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,SERF2,KIDINS220,UBAP1,PMEPA1,NSF,PEX13,RTTN,ZBTB37,URB2,RIBC2,NDUFB5,KLHL18,AP1B1,SLC25A44,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,KMT2A,NAA35,MPP6,PDK1,SFXN4,MTIF2,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,RTN4,MYNN,MON2,FOXO3,MAD2L2,ZNF483,DCTPP1,COMMD9,RGS17,LRP2BP,NISCH,RDX,HARS2,NLGN3,MAP3K14,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,COL26A1,HELZ,RNF138,PGAM5,BRWD3,RABEP1,LRRC41,STK4,CERS5,TRPM6,RCHY1,ZNF107,SIRT2,SLC29A1,CUTC,EDC3,ANAPC1,RAP1A,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,LONP1,TRIP13,TIMM50,TRIM13,GPM6A,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,NOCT,TNRC6A,LDAH,SLC12A7,RELL2,PAX2,GPAT3,DPF2,ALG8,MED13L,C11orf54,PHGDH,ADGRG6,RHBDD1,TOX4,MCAM,BANF1,BUD31,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,PRDM1,BLOC1S4,ATAD5,INTS5,SDCCAG8,EXOC4,PDSS2,ASH1L,PCNT,CELSR3,SLC5A5,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SULT1C2,SH2D3A,DBF4,TKFC,PPHLN1,CLSTN2,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,SYMPK,NAPEPLD,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 5.170e-18 | -39.80 | DODD_NASOPHARYNGEAL_CARCINOMA_DN | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_DN | 1265 | 268 | 17758 | 2279 |
IKBIP,NUP160,ZNF37A,PMAIP1,CEP135,FXN,SEH1L,NRAS,KLHL23,NOL8,KIF15,WDHD1,MCM2,RBM28,DDX60,OSBPL1A,BRCA2,RAD18,CCNT1,LUC7L3,LRRC40,HIC2,VASH2,BLMH,LRRC37A,NMD3,ZNF532,PTPN14,EFNB2,WDR75,TRIP6,FAM189B,PDCD5,YARS2,FKBP1A,SH2B3,CHN1,NAV1,EIF2S2,UBE3A,ASAP1,INTS7,ATIC,MYC,GTF3C3,NOC3L,FMNL2,PPA1,ANGPT2,NOM1,IFRD1,PRIM2,ALG6,POLA1,MTR,EPRS,ASCC3,TSR1,MTHFD2,C6orf141,TRAP1,VCAN,UMPS,MAP2K4,CPT1C,AMOTL1,DDX18,URB2,OLA1,ISG20L2,NUP43,NOP56,FLAD1,SPG21,ASNS,ERI1,UCHL5,INTS12,SSBP1,MTHFD2L,DENND1A,CDK12,CASP8AP2,C18orf21,RFC4,PMS1,RFC3,GARS,STAMBP,EIF3J,ARHGEF10,LGALS1,PNN,POLG2,MAT2A,SLC39A14,DNAJA3,MBTD1,HOXA3,RPS6KB1,NOLC1,XRCC4,TROVE2,YEATS2,CEP170,UTP14A,C10orf2,TCF3,ZNF280C,ID2,SF3A3,MYNN,RSRC1,NEDD4,SUV39H2,NOP16,TRIAP1,NT5M,SOX6,HNRNPM,MBTPS2,NAV3,DDHD1,ERICH1,PSAT1,LSM12,KCNMA1,LDHA,ADSL,NOP58,CCDC150,DDX50,POLE2,ORC5,SLCO5A1,AEN,PIGM,NF1,RCHY1,TTI1,SLC30A7,ANAPC1,SRSF2,PHF5A,DHX33,METTL8,UBAP2L,RAN,PCOLCE2,YARS,TMPO,METTL1,LAMA4,ATF4,ZNF124,ZNF195,CDK4,PSMG1,MARCKSL1,MTHFD1L,PITPNB,BRCA1,CAV1,SOX4,FLVCR1,CCDC28B,CHAF1A,GLS,HPRT1,GATA6,EME1,ZC3H8,MCM6,AK2,FN1,ZIC2,QSER1,TIMM10,PHGDH,SUB1,MCAM,TIMELESS,PRF1,NIPSNAP1,ZNF234,NAA38,CAMKK2,LAMC1,PPAT,HAUS6,XPO5,ELP3,PSMA1,POP1,PWP1,PALB2,FSCN1,SDCCAG8,SLC16A1,PTRH2,PFDN2,C12orf45,ZBTB24,TCF12,FEZ2,ARID2,RBFOX2,SMARCA4,RSL1D1,SPATS2,DDX60L,SEMA6A,DENR,CAD,RRN3,SOCS1,NUP133,DNAJB6,CPSF3,PRMT3,PTBP2,COL5A2,TFCP2,CPOX,NLN,R3HDM1,SLC35F2,TOR1AIP2,DKC1,RAD54B,EXO1,RANBP2,RBBP8,ADNP,ZNF557,FKBP5,PUS1,HEATR1,SMG1,TMEM33,DNAJC2,MCM10,DBF4,BZW2,ADH5,GART,SACS,TANK,DSG2,KDELC1,SHMT2,POLR1B,FBL,PCSK6,GINS3,FGF2,SMARCAD1,PSMC3IP,ABCF2,MARS,C8orf33,NAPEPLD,TARS,NCBP2,RBPJ,RWDD2B,ZAK,KIF1B |
| 1.334e-17 | -38.86 | binding | molecular function | GO:0005488 | 13878 | 1949 | 16491 | 2164 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,HMOX2,LPAR3,CIAPIN1,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,AP1M1,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,EHMT1,AP4B1,NFIA,KIF15,KRBOX4,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,ZNF197,PYCR1,SLC7A1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,RIOK1,DIRAS1,RUNX1,TPM1,ZNF532,BANP,EPM2AIP1,FAM189B,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,CNST,UBE3A,DHX37,APLF,MED24,TNPO3,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,LRRC20,KLRD1,ZNF675,GATAD2B,WDR61,STAG1,KCNQ3,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,SNAP25,TRIM37,SRA1,USP46,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,LCLAT1,ZMAT2,CBWD5,MCM9,UBL5,RPGRIP1L,ZBED2,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,LRRC75A-AS1,ZNF480,EIF3J,CCNDBP1,KCNH3,MEF2D,GSTCD,DSP,NUDT15,VPS53,MAT2A,FBXL5,ZFAND3,ARHGAP21,KDM4B,ELP2,MISP,NSMCE2,ARL13B,HOXA3,RPS6KB1,CENPBD1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,GAS6,TRIM22,IP6K2,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,CBWD6,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,ZNF710,FBXL19,ACTR3B,SAMD4A,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,USP42,LDHA,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,ACOX1,AEN,BMP4,UQCC1,GPATCH11,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,AAMDC,SCAF8,HNRNPLL,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,PHF5A,COPS4,NCKIPSD,HKR1,ZNF3,ZMYM2,SLC25A23,FAM184A,DBN1,DSC3,FMNL3,RBCK1,AEBP2,ATF4,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,LAMA2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,PRSS3,NKD2,MAPK8IP3,FAN1,SMAD7,LAMTOR3,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,RNFT2,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,WNT16,LRSAM1,SNX29,NIPSNAP1,WARS2,USP49,IFT43,SETD2,OBSCN,MAPK1IP1L,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,SNX24,SIL1,DTD1,GGT7,DDX10,SLC52A2,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,PAPD4,ARID2,SLC48A1,OSBPL9,NTSR1,RPS29,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,RADIL,PAG1,PPP1R9A,DDX60L,SEMA6A,ZNF121,URB1,FDX1,PLXNB1,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,MYH15,AHCYL1,SPIDR,IPO11,PRPF19,SOBP,KDM3B,ARHGAP17,AKAP8L,SSFA2,KIRREL2,RAB7A,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,HSPB8,MED20,EIF2B3,FAHD1,MUTYH,PARD3,FAM214A,ZNF507,DMGDH,NIFK,ESCO1,MINK1,KIZ,MCM10,AUH,HM13,RFX1,AGO2,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,TTC1,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,FOXN3,SMARCAD1,ABCF2,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,C8orf33,POLR3A,DKK1,CDH24,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,CUL4A,PRKCSH,GYG1,NBEAL1,PRKCA,LRP5L,GABPB2,EXOC1,S100A10,ZFYVE28,SUCLG2,DPH6,CHD2,CSGALNACT2,ZNF646,ACADS,FAM127A,OSBP2,VSNL1,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,SPOP,OSBPL1A,DOT1L,GZF1,GNAI1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,HSPBAP1,NSMCE1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,BMI1,BLMH,SPOCK2,RFXAP,ZMAT3,SPOCK3,NMD3,CADM4,PRPF38B,C9orf78,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,DLGAP4,TATDN3,CENPB,DPM3,CRACR2A,PRPF39,C1orf50,PDCD5,NDUFS7,FAM192A,HR,SLC7A11,USPL1,NOVA2,SCAF1,MYC,MFAP2,PLEKHA2,CNOT4,CAV2,EXOSC2,KIAA1143,PRIM2,RREB1,PCCA,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,NELFA,MTR,ZNF850,ANGPTL4,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,SMYD3,CPT1C,ZNF254,SYT17,BIRC6,KIAA0232,UROD,POP5,PTPRG,CORO6,PABPC1L,HNRNPA3,RING1,FLNB,IGSF1,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,PPID,SOCS6,MRPS27,DTNBP1,RMDN3,TTC3,CMPK1,ARL14EP,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,PCMT1,LRRC8A,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,G6PD,MBTD1,LARGE,CBWD1,TRAF3,TBXA2R,XRCC4,SETD6,MID1,VWA8,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,INPP1,GIGYF2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,NAV3,SLC40A1,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126B,PACS1,BMS1,GUF1,KLF6,ZFP62,INF2,DDX50,IREB2,ZNF155,COQ9,ORC5,SVIL,ATM,APAF1,ADK,DDIT3,IPO4,KAT6A,ZNF76,LETM1,EIF3C,KMT2E,ATRX,RARS2,PPIL1,DST,KANSL1,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,YARS,CARM1,SRPK2,DEAF1,DTNB,TNK2,SESN2,ZNF195,SKAP2,SIRT6,ITPA,ARRDC3,VWCE,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,EIF4ENIF1,ZGRF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,MTCH1,DCTN3,FBXO45,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,SMG7,EVPL,TIMM10,NAMPT,RNF141,ELL,P3H1,ZNF354A,WDR27,TENM3,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,HSD17B14,ZNF629,MSI2,HBG2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,EIF2A,SYT1,AGAP1,HERPUD1,UBE2E1,MGAT2,POP1,APBB3,BICD1,FSCN1,FAT1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,TBCK,FNBP1L,PDE9A,AGO3,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,CEMIP,TMEM183A,TNXB,SMARCA4,PBX1,COBLL1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,SOCS1,NVL,CBR4,SNTG2,FHIT,ITGAX,VCL,TMEM120B,UTP4,GNG5,AUP1,NARS2,NPW,PRAME,ANTXR2,GRHL3,MRRF,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ALAD,DUS3L,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,ATF7IP,IGF2BP2,SEMA3E,ENOX1,PIP4K2A,BMP6,MFHAS1,GFM2,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,CRAMP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,GPHN,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,SULT4A1,ASAP3,ZNF324B,SCMH1,PDE2A,PEAK1,EIF5B,NAALADL2,CTIF,ZNF221,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,ZSWIM6,ASCC1,GNB3,WDR74,CACNA1H,CSPP1,CHAC1,HLTF,NT5C3A,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RASSF3,RABGAP1L,PDS5B,WIZ,FNIP2,ZNF148,HRG,FXN,AVEN,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,MSRB3,AKAP12,MCL1,PLEKHM3,DCUN1D5,RBM28,TMSB4X,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,TMEM139,FIS1,FIP1L1,RBP1,MEF2C,LPP,CARS,ADGRE2,TNNC1,HERC2,EP400,CLDN15,TRIP6,SLK,KHDRBS1,SIRT7,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SH2B3,DDX56,EIF2S2,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,MAP3K12,AGL,FMNL2,TOMM34,SERBP1,HMGCR,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,CPT1A,MBNL2,ONECUT2,ABCF1,ZNF655,NCDN,ZNF783,LRP1B,GTF2A1,LEMD3,CDK9,SURF1,ZNF160,GPN1,ADGRE5,SENP3,CNOT6,WDR33,MB21D2,COG5,SPRED2,FAM208B,DNM3,ABCA3,MAP2K5,ZNF516,TRERF1,EVA1C,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,AGAP6,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,NT5C,CEP63,LSM10,MALL,GARS,KRT7,FAM111B,STAMBP,NPM3,ASUN,LGALS1,ARHGEF10,DRICH1,ADAM32,ATP6V0A1,FKBP3,FGFR1,PDE8B,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,PAM,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,LRCH1,TRIM36,NOL4L,ZNF786,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,TMSB10,PVRL3,ACAP3,ARHGAP1,SOX6,HNRNPM,DIS3L2,ULBP1,NUDC,DDHD1,FAM98A,FGF9,FBXO17,CEP83,CLYBL,POLK,FRA10AC1,R3HDM2,FAM126B,IL6R,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,KISS1R,RPA1,TRIB3,TOE1,ETFDH,RARS,BAZ2B,PXDN,POLE2,STX1A,ARID3B,PTPN4,PSAP,IGBP1,NUDT22,ANAPC4,CORO2B,KDM4C,SRM,GPBP1L1,PPARGC1B,TFIP11,POLR1A,MFGE8,HECTD3,NREP,CSNK2A1,RNF43,TTI1,SEC16A,BIRC2,GIT2,ABL2,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,TMPO,PTPRK,SF3A1,CDC37,FLNC,METTL1,CHD9,ZNF124,SLC3A2,ABCC4,SKIV2L2,HARS,ZNF414,BAZ2A,KATNAL1,GDPD1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,TOM1L2,TP53BP1,PER1,FAM206A,EEFSEC,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,C2CD5,TMEM158,CHMP4C,SEPHS2,XYLB,NOMO3,SARS,TTN,AOC3,MCM6,STX8,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,RNF40,KIAA1958,ABCA5,TRMT13,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NT5E,NAA38,CAMKK2,LAMC1,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,ATXN7,ITPRIPL1,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,PPP1R12B,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,CYLD,FAM207A,LPCAT2,RBFOX2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,ZNF709,PELP1,RPAIN,KDM1A,DENR,METTL16,CAD,ZBTB21,DUS4L,UBR1,DNAJB6,IKBKB,CYB5D1,ZDHHC6,HIRIP3,RNF2,ETF1,ZFP37,CORO1A,PRMT3,CASP10,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,TUBA1A,DDX41,NARS,GLTSCR2,C1QTNF1,CPOX,MANBAL,TMEM123,AKAP13,ENC1,ARL5B,NUP214,PUM3,USP36,ATP5D,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,ITGA2,ZNF436,PUS1,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,UNC13D,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,C15orf57,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ANXA7,ZNF561,IFIT5,PRICKLE2,HIST2H3D,DDX31,SELT,FBXO31,CD44,PCK2,HSD17B12,ADAMTSL3,ZNF654,ZMYM5,TPM4,DHX34,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,CHCHD6,ZRANB3,MKX,CENPP,TPD52L2,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,MYRF,RWDD2B,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRDX6,PRKAB2,TNFRSF21,DDX19A,PLRG1,ENAH,ADAMTS6,IKBIP,RAC3,AARS,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,VPS52,ME1,CEP135,MEIS3,PRADC1,TRMT10A,FUT11,DDN,DPF3,SNU13,SETD1B,ATG9A,NR6A1,NOL8,EYA3,TCEB3,CUX1,DESI1,HSH2D,SEMA3F,MAK16,SAP30BP,SH3GL1,SKIL,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,SYNPO,ZNF598,PTPN14,EFNB2,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,AK6,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,CD226,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,PTPN12,TTYH2,RABAC1,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,NSF,UBAP1,PMEPA1,ZZEF1,ZBTB12,D2HGDH,RIOK3,PURB,PEX13,MACROD1,MAP2K4,ZFHX2,PTCD2,TBKBP1,AMOTL1,RWDD1,LIN28B,ZBTB37,RIBC2,HFM1,SPRYD7,OLA1,KLHL18,SPATS2L,FOSL2,AP1B1,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,PLEKHA4,NAA35,RFC4,ZCCHC14,MPP6,CFAP221,RFC3,PDK1,MTIF2,DLG4,KIAA1586,MED16,GALK2,PNN,POLG2,TBC1D16,STK10,DHX57,DCBLD2,VDR,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,MDN1,KLHDC4,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,CEP126,LIAS,MON2,IKBKAP,NOL3,GDPD5,REEP5,FOXO3,MAD2L2,TMCO6,NEDD4,DCTPP1,ZNF239,ZNF483,RGS17,COMMD9,FTCDNL1,PTRF,LRP2BP,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,MAP3K14,LARP4B,NT5M,PLEKHG4,MBTPS2,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,PTK2,APTX,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,FBXO21,KLHL22,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,RABEP1,BORCS5,LRRC41,STK4,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,CERS5,FANCD2,TRPM6,RCHY1,PLOD1,ZNF107,BCOR,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,WNT2B,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ZNF804A,RAP1A,CMSS1,LONRF2,YLPM1,THADA,ATG3,ZNHIT6,RELB,HYAL1,IPP,JOSD1,POLR3B,PCOLCE2,SLC27A5,CCDC121,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TRIM14,TIMM50,ELOF1,LAMA4,ZBTB17,TRIM13,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,LVRN,GPCPD1,HDAC8,PCED1B,CAV1,ZSCAN2,SOX4,SERGEF,CHAF1A,CDHR3,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,SUFU,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,ABCC3,GALNT10,COPS6,ZNF397,NOCT,DMTF1,EMSY,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,FN1,SEC24D,TAF1,PAX2,DPF2,CDIP1,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,DDIT4,TOX4,CEP164,ATXN2,BANF1,BUD31,CCDC112,SEMA3D,GLTP,NRIP1,N4BP2,POLR1E,CPSF3L,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,C11orf65,PRDM1,BLOC1S4,DNAH14,ISG15,UBAP2,MYBBP1A,ATAD5,INTS5,SDCCAG8,RRAGA,HK2,EXOC4,PTRH2,KIAA1328,ZFP90,TMEM182,PDSS2,ZBTB24,ZNF706,ASH1L,EXOC3-AS1,PCNT,MMRN2,CELSR3,MYO7A,CSTA,PUDP,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,FARSA,BRE,CCDC50,CAMTA2,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,TSPAN14,TMEM14C,HTRA2,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,DISP1,USP11,TSPAN5,YDJC,TNIK,DNAJA4,SH2D3A,SULT1C2,NSUN6,H2AFJ,DBF4,TKFC,CLSTN2,LETMD1,PPHLN1,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,IL17RE,GART,CTNNBL1,TANK,DSG2,SHMT2,TTC17,UTS2,AMOT,DMRT1,MSX1,TEAD1,PPP1R21,PSMC3IP,ANKMY2,MARS,PHACTR2,ARHGAP32,LENG8,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,MPP7,ZNF330,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,ZAK,MMP16,ARHGAP27,HRH1 |
| 1.366e-17 | -38.83 | NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | MSigDB lists | NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | 1225 | 260 | 17758 | 2279 |
POLB,AARS,GABPB2,PABPC4,SREBF2,ZFHX3,ME1,ZNF148,CHD2,NR6A1,RNMT,UPP1,NOL8,TCEB3,CUX1,MCM2,SPOP,SKIL,SUPT4H1,BRCA2,CCNT1,LUC7L3,RUNX1,EGR1,ZHX3,PRPF31,KHDRBS1,RSF1,PARN,IGF2BP3,INTS7,ATIC,MCM5,MYC,MED24,GEMIN4,PRPS1,PABPC1,TERF2,SCAF11,EXOSC2,PRIM2,RREB1,POLA1,ARID5B,SMARCD3,ARID1A,KPNA1,HIF1A,CDK9,UMPS,BPNT1,NCOR1,ZNF254,TRERF1,NPAS2,OLA1,FOSL2,HSPA1A,IGSF1,NOP56,TERF2IP,BCAS2,ACD,INTS12,NT5C,MSH4,CMPK1,RFC4,PMS1,RFC3,KRT7,MED16,POLG2,ERC1,VDR,TAF2,ELP2,SMARCC1,ALKBH1,NOLC1,XRCC4,TROVE2,HMGA2,XPC,TCF3,TRAK1,NFX1,ID2,SF3A3,FARS2,MLH1,TRIM22,IKBKAP,NOL3,RPS6KA5,FOXO3,TADA3,ABL1,SNW1,PTRF,PSMG4,UPF2,CELF1,NT5M,APEX1,POLK,APTX,NOP58,RPA1,SLC23A2,RARS,SRCAP,NSD1,POLE2,HNRNPH3,ORC5,ATM,ADK,DDIT3,KAT6A,ZNF76,ATRX,UBN1,PPARGC1B,SLC29A1,BCOR,SIRT2,SNAPC4,MAP2K3,SMARCB1,AMPD3,SRSF2,PHF5A,JAZF1,XRCC2,ZEB1,RAN,POLE3,YARS,HCFC2,ETV1,OGG1,CARM1,TRIP13,SRPK2,SF3A1,METTL1,DEAF1,ATF4,PPARG,TSN,MED27,HDAC8,BRCA1,DYRK1B,UBTF,GEMIN5,HPRT1,SUFU,GATA6,CHD3,PER1,MKL2,TNFRSF1A,RAD51B,PQBP1,SARS,FOXO1,PAX2,SMG7,SUB1,ELL,ZNF354A,VPS72,BUD31,TIMELESS,GTF2H1,GMDS,NRIP1,POLR1E,CPSF3L,NT5E,CAMKK2,PPAT,TSTA3,TRA2A,ELP3,JMJD1C,LIG4,PRDM1,SUPT5H,TCF7L2,PGD,POP1,PWP1,BICD1,MYBBP1A,SYNCRIP,INTS5,TCF12,ID1,ASH1L,RBFOX2,PBX1,RPAIN,RRN3,NRF1,IKBKB,FHIT,CPSF3,MAML3,KAT8,TFCP2,SFSWAP,POU2F1,ATXN1,DKC1,BATF3,WARS,RAD54B,EXO1,SMAD3,RBBP8,HNRNPR,KLF4,COPS5,CEBPZ,ARNTL,INTS9,NFRKB,MED20,MUTYH,SMG1,AUH,MAP3K13,DBF4,ATF7IP,ZNF346,BMP6,FBL,SNAPC5,KDM5B,KDM5A,SMARCAD1,FOXN3,SCMH1,MEN1,HSPA1B,POLR3G,GADD45A,TBX3,SET,MSH3,ZRANB2,NCBP2,RBPJ,NFKBIB,POLR1C,NR2F2 |
| 1.372e-17 | -38.83 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | 844 | 196 | 17758 | 2279 |
SRM,WDR74,PPARGC1B,DDX19A,TMEM109,ANKRD18A,ENAH,SLC29A1,STK33,IKBIP,HMOX2,CUTC,MAP2K3,CIAPIN1,THADA,DHX33,THAP4,ATG3,TRMU,UBAP2L,METTL8,PAK1IP1,PCOLCE2,PRADC1,FXN,TRIM14,TRIP13,SEH1L,ELOF1,DEAF1,TXLNG,BAZ2A,KLHL23,GNL3,AP4B1,NOL6,PACRGL,MINA,DCUN1D5,SOX4,FLVCR1,RBM28,GEMIN5,RAD18,INSIG1,LUC7L3,SYNGR2,C9orf78,IFT57,PRPF31,HES6,TIMM10,LYRM2,PDCD5,FKBP1A,MCAM,DHX37,MYC,MED24,CCDC124,GEMIN4,ALDH18A1,PRMT5,MRPL21,LPCAT1,COQ3,PRPS1,LRP3,SERBP1,MYB,MSI2,TIMM8B,PDE4A,MYO10,XPO5,RDH10,C19orf70,PWP1,POP1,TSR1,MYBBP1A,TASP1,SYNCRIP,FSCN1,CCDC85B,SLC16A1,SQLE,UMPS,SENP3,C7orf50,IFITM2,DDX10,DHCR7,C12orf45,ZBTB24,BCCIP,USP7,MPI,DDX18,LPCAT2,SLC2A1,KLHL18,ISG20L2,TMEM177,UBL5,RPGRIP1L,ZSCAN5A,METTL16,FARSA,TMEM150C,GLYR1,CYB5D1,MGLL,TMEM120B,MTHFD2L,LYST,HN1,ACSL5,ANTXR2,WDR36,MPP6,SFXN4,NLN,DKC1,NUP214,DHX57,DCBLD2,PES1,ELP2,DUS3L,DCXR,PEMT,TIMM17A,ATG7,SRFBP1,HEATR1,SCARB1,NOLC1,PDCD11,BAG1,FGFBP3,DNAJA4,C10orf2,B4GALT5,MRI1,TCF3,SLC25A12,VARS,IKBKAP,PHLDA2,BZW2,HDDC2,DCTPP1,NPRL2,GART,SACS,PSMG4,NOP16,CFDP1,TRIAP1,PMPCA,COPS7B,DDX31,EXOSC4,POLR1B,LDLRAD3,NUDC,FAM98A,SLC40A1,TRNP1,DDX24,MON1A,ABCF2,SLC35G1,LDHA,SCFD2,RANGAP1,CCDC113,IL6R,RHOT2,EIF5B,POLR3G,MRPL36,INF2,ZDHHC11,NOL10,WDR35,ADAT2,SLC25A19,NCBP2,RBM26,NR2F2,POLR1C,GCSH,GPATCH4,IPO4 |
| 1.424e-17 | -38.79 | cell | cellular component | GO:0005623 | 15728 | 2106 | 17570 | 2233 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,FAM222B,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,WDR60,MED24,TNPO3,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,ZNF675,GATAD2B,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,NDUFB3,CD96,SPG21,ACD,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,LRRC75A-AS1,KCNH3,MEF2D,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,RAPGEFL1,PTGS1,ZNF710,ACTR3B,PNMA1,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,MTMR1,TRIM16,FAM13A,HNRNPLL,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,FAN1,LAMTOR3,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,WNT16,LRSAM1,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,CASS4,GGT7,PTP4A2,USP7,ID1,SUCLG1,UPK3B,PAPD4,ARID2,NTSR1,SLC2A1,RADIL,PAG1,PPP1R9A,NUP133,CCDC40,MYH15,BCAP29,SPIDR,PRPF19,SOBP,KDM3B,AKAP8L,SSFA2,KIRREL2,TEX19,RAB7A,EIF3H,TJAP1,EXO1,IFT81,HSPB8,EIF2B3,MUTYH,PARD3,DMGDH,NIFK,MINK1,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,POLR1B,MON1A,FOXN3,SMARCAD1,SLC35G1,TOP3A,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,NBEAL1,PRKCA,LPIN1,S100A10,SUCLG2,DPH6,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,SPOP,OSBPL1A,DOT1L,GZF1,DDAH2,CCNT1,LSM14A,SH3RF1,HSPBAP1,NSMCE1,ARL6IP5,CFD,HIC2,TNFRSF10D,BMI1,BLMH,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,CRACR2A,SSR4,TECTA,MYC,PIGG,EXOSC2,ANAPC13,PRIM2,RREB1,RDH10,RAPGEF4,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,NCOR1,BIRC6,PLEK2,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,RMDN3,CMPK1,ARL14EP,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,MBTD1,SLC4A7,TRAF3,TBXA2R,XRCC4,SETD6,VWA8,NOSTRIN,BRAF,RCAN1,INPP1,PHLDA2,SFR1,ABL1,NEBL,ELP5,SDCBP2,S100A14,NAV3,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,MINA,TMEM216,KSR2,MTHFD1L,SGK2,KMT2C,MPC1,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,EVPL,NAMPT,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,ZNF629,MSI2,HBG2,ZNF234,PPAT,TRA2A,JMJD1C,ELP3,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,CEMIP,PIGH,SMARCA4,ARSJ,PIBF1,SBDS,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,EDEM2,S100A16,ALAD,DUS3L,KPNA3,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,CRAMP1,RPS6KB2,MARCH9,ARNTL2,SLC6A16,DNMBP,KDM5B,GPHN,CRIM1,SULT4A1,ZNF324B,SCMH1,PEAK1,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,TRAPPC12,ASCC1,CACNA1H,CHAC1,NT5C3A,COA1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,HRG,LYRM5,AVEN,MSRB3,PLEKHM3,DCUN1D5,RBM28,TMSB4X,DDX3X,ZNF266,BRCA2,FIP1L1,MEF2C,LPP,ADGRE2,TNNC1,CLDN15,TRIP6,SLK,NHS,RSF1,CLINT1,DDX56,EIF2S2,SLC38A5,ALKBH8,NOC3L,CALN1,PRMT5,ZNF518B,AGL,COQ3,FMNL2,SERBP1,HMGCR,FADS1,MYO10,RB1CC1,EIF4A2,EVI5,CPT1A,MBNL2,ONECUT2,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,ADGRE5,CNOT6,WDR33,SPRED2,ABCA3,MAP2K5,ATP6V1A,NPAS2,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,YEATS2,ANKS1A,TRIM36,NOL4L,TGFB2,RSRC1,SUV39H2,TMSB10,ARHGAP1,HNRNPM,LYPLA2,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,GPAM,PSAP,IGBP1,DOCK6,NUDT22,CORO2B,KDM4C,BCAS4,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,RNF43,TMEM132A,COX10,BIRC2,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,TMPO,PTPRK,SF3A1,CDC37,FLNC,METTL1,CHD9,GCNT2,SKIV2L2,HARS,ZNF414,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,C2CD5,XYLB,SARS,TTN,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,TRAPPC6B,SUPT5H,NR2F1,PGD,PWP1,SPAG9,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,BRSK2,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,PELP1,RPAIN,CAD,ZBTB21,DUS4L,UBR1,FSIP2,ARMC5,IKBKB,ANO8,RNF2,HIBCH,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,AKAP13,ENC1,ARL5B,NUP214,PUM3,TMEM186,USP36,RBBP8,SLC30A3,CLEC16A,ITGA2,ZNF436,NFASC,ZNF18,SEPT5,PPIL3,ZNF589,MAP3K13,ARFIP2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,PRICKLE2,HIST2H3D,CD44,HSD17B12,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,NEU1,ARMC3,ZRANB3,MKX,POLR3G,CENPP,TPD52L2,ADAT2,GLG1,NDUFAF5,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,GIPR,RPS16,RNF111,ME1,TRMT10A,SEH1L,DDN,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,HSH2D,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,CCDC53,ANKRD17,OPHN1,PID1,TGFBR2,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,LYRM7,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,PTCD2,AMOTL1,TRPM2,CCDC58,LIN28B,OLA1,SPATS2L,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,RFC4,CFAP221,RFC3,WDPCP,POLG2,STK10,DHX57,CPED1,DCBLD2,TAMM41,VDR,DNAJA3,H2AFX,ACP1,MDN1,ANXA2,PDCD11,NCOR2,SCAMP3,CA11,C10orf2,ZNF280C,SLC25A12,MLH1,CEP126,LIAS,IKBKAP,NOL3,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,PHYKPL,UPF2,COPS7B,EXOSC4,YBX3,LARP4B,NT5M,TSHZ1,WDFY3,WDR18,PTK2,APTX,MMAA,ECH1,POLR2A,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,POLR3B,SLC27A5,GALNT18,OGG1,PRKACB,TRIM14,ELOF1,ZBTB17,TXLNG,CMIP,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,PAF1,RHOU,UBTF,EPN2,UBE3D,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,EMSY,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,CDIP1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,N4BP2,POLR1E,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,C19orf70,DNAH14,ISG15,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,ZBTB24,ZNF706,MYO7A,FAM210A,SLC9B2,GBF1,ZSCAN5A,MIEF1,VPS18,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,MET,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,OXLD1,H2AFJ,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,ZRANB2,NCBP2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,ARHGAP26,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,EMC8,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,KRBOX4,NFIA,SLC9A5,ZNF197,RBSN,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RUNX1,TPM1,P2RY11,EPM2AIP1,PDCD7,CHN1,CNST,CCDC88C,MRPL21,RABEPK,NOM1,MYB,KCNQ3,STAG1,ALG6,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,SUGCT,GTF2H2C,DDR2,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZSWIM7,CLCN6,INTS12,MSH4,PXK,PEG10,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,CCNDBP1,NUDT15,DSP,SLC39A14,ARHGAP21,MISP,ELP2,KDM4B,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,UQCC1,CYP24A1,CUL7,AAMDC,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,PHF5A,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KCNH2,KRTCAP2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,DPP4,PRPF4,PPP3CC,BEND6,UQCC2,CLK1,SMAD7,MAPK8IP3,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,ICE2,PNPLA3,NIPSNAP1,IFT43,USP49,SETD2,HAUS6,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SLC52A2,BCCIP,MPI,SART1,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,KIZ,ESCO1,RFX1,AGO2,ESRG,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,PCSK6,TRNP1,AP4S1,ABCF2,FERMT2,RANGAP1,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBPJ,KIF1B,XPO6,LUZP1,GYG1,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,VSNL1,CAMSAP2,SUPT20H,DDX60,DENND4A,SON,GNAI1,TRRAP,LUC7L3,XPNPEP1,NRP1,NMD3,RFXAP,CADM4,JUP,CDC42EP2,LARS2,PRPF31,TATDN3,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,NOVA2,USPL1,CNOT4,PLEKHA2,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,NELFA,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,ZNF254,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,FLNB,RING1,NOP56,DECR1,PPID,LPIN2,MRPS27,SOCS6,TTC3,CASP8AP2,PCMT1,PREX1,SATB2,GNL1,MARCH6,MEGF11,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,RPS6KA5,DYNC2H1,CELF1,ERRFI1,CLK2,FER1L5,PSAT1,APEX1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,KAT6A,ZNF76,EIF3C,KMT2E,RARS2,DST,CNIH3,KANSL1,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,ARRDC3,TFPI,PITPNB,COTL1,ST3GAL5,CC2D1B,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,RHOBTB1,ZCCHC8,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,P3H1,ZNF354A,TENM3,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,TMEM117,SLC16A1,PFDN2,TBL1X,FNBP1L,N4BP2L2,AGO3,NR2C2AP,CHMP2A,SNX27,DLL4,PSTPIP2,TNXB,TBCCD1,PBX1,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,UTP4,AUP1,PRAME,GRHL3,POU2F1,MRRF,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,ARC,RNF130,SMG1,TMEM33,TMCC1,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,WDR26,IGF2BP2,ATF7IP,MED18,ENOX1,GFM2,BMP6,SCN1B,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,PPP1R9B,ZNF821,FGF2,PSPC1,KDM5A,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RASSF3,RABGAP1L,WIZ,ZNF148,FNIP2,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,HERC2,CARS,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,EMC10,PEA15,BDNF,GTF2H3,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,GTF2A1,CDK9,ZNF160,SENP3,COG5,ZNF516,DNM3,FAM208B,TRERF1,BTBD2,DDX18,ACTR3,PDK4,MYH9,NECAP1,TUBB6,SAFB2,EEA1,STAM,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,NPM3,ASUN,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,WDR7,FUS,BRCC3,LAMA5,ZNF786,SERINC5,INSIG2,XPC,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,NUDC,ULBP1,DIS3L2,FAM98A,FBXO17,CEP83,CLYBL,CEP295,MRPS10,R3HDM2,UBE2K,RPA1,RARS,TOE1,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,NREP,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,EEFSEC,FAM206A,PER1,TNFRSF1A,DLX2,CHMP4C,MCM6,PGPEP1,STX8,ITPRIP,HSD17B10,MEX3A,HES6,TRIM15,ZFP36L1,BARX2,RLF,DNAH1,PPIL2,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,PAXBP1,CRADD,TLE3,BCS1L,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,TMEM94,DNAJB6,ZDHHC6,HIRIP3,ZFP37,ETF1,AKNAD1,CORO1A,PRMT3,CASP10,SEC24A,SKIV2L,WDR36,DDX41,TUBA1A,NARS,CPOX,TMEM123,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,TIMM17A,ABHD3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,NDUFV1,SACS,CWC27,DDX31,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,TPM4,PEAR1,C11orf49,CHCHD6,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,MYRF,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,DDX19A,TMEM109,ENAH,IKBIP,UBR5,AARS,RAC3,MGA,VPS52,PAK1IP1,MEIS3,CEP135,FUT11,SLC38A6,DPF3,EYA3,GNG7,NOL8,CUX1,TCEB3,DESI1,SAP30BP,MAK16,SH3GL1,HSDL2,ZNF81,DNAH2,CCNB1IP1,TXN2,PTPN14,WDR75,IFT57,CELSR1,EGR1,ZHX3,AK6,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,NSF,PMEPA1,UBAP1,PEX13,RTTN,ZBTB37,URB2,RIBC2,NDUFB5,KLHL18,AP1B1,SLC25A44,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,KMT2A,NAA35,MPP6,PDK1,SFXN4,MTIF2,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,RTN4,MYNN,MON2,FOXO3,MAD2L2,ZNF483,DCTPP1,COMMD9,RGS17,LRP2BP,NISCH,RDX,HARS2,NLGN3,MAP3K14,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,COL26A1,HELZ,RNF138,PGAM5,BRWD3,RABEP1,LRRC41,STK4,CERS5,TRPM6,RCHY1,ZNF107,SIRT2,SLC29A1,CUTC,EDC3,ANAPC1,RAP1A,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,LONP1,TRIP13,TIMM50,TRIM13,GPM6A,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,NOCT,TNRC6A,SLC12A7,LDAH,RELL2,PAX2,GPAT3,DPF2,ALG8,MED13L,C11orf54,PHGDH,ADGRG6,RHBDD1,TOX4,MCAM,BANF1,BUD31,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,PRDM1,BLOC1S4,ATAD5,INTS5,SDCCAG8,EXOC4,PDSS2,ASH1L,PCNT,CELSR3,SLC5A5,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SULT1C2,SH2D3A,DBF4,TKFC,PPHLN1,CLSTN2,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,SYMPK,NAPEPLD,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.768e-17 | -38.13 | prostate-carcinoma | COSMIC cancer mutations | prostate-carcinoma | 9403 | 1391 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,SBF2,CCNL2,HMOX2,ABHD6,LPAR3,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,HMBOX1,NRAS,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,ABCC2,PYCR1,AHNAK,SSU72,RAD18,LRRC40,DIRAS1,RUNX1,VASH2,ZNF532,SLC25A26,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,MRPL21,PABPC1,SAMD3,MYB,NOM1,RABEPK,GATAD2B,ZNF675,STAG1,ALG6,KCNQ3,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,IRS1,DYNC1H1,TSR1,NME7,EHMT2,TRAP1,FGFBP1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,SDSL,RAB11FIP4,C16orf45,MAB21L3,VTI1A,DDR2,NUP43,LCLAT1,RPGRIP1L,CD96,TBC1D22A,SETD5,CLCN6,MMP14,C16orf58,MSH4,PEG10,TRMT12,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,PCNXL2,MEF2D,KCNH3,DSP,MAT2A,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,POLR3E,CAMKMT,RPS6KB1,CEP170,CATSPERG,MAPT,RAB30,HMGA2,SHQ1,XRRA1,ATG2B,TRIM22,ZNF691,TTLL11,SNW1,POLR3D,TAF3,UNC13A,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,C15orf41,SAMD4A,PNMA1,SPTAN1,LSM12,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,TRIM16,SLC25A21,FAM13A,NLE1,SCAF8,MAP2K3,AMPD3,ECM1,COPS4,NCKIPSD,ANKRD11,TRIML2,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,MIOS,PPARG,CDK4,ANK2,HSPA5,SUMO3,LAMA2,KCNH2,ODC1,CRYBG3,LSG1,CXADR,MLLT10,C1orf122,BSN,TCF7L1,LSS,INSIG1,CHD3,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,MAGI1,USP15,FOXO1,ITFG1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ARID1B,SUB1,RNFT2,MBD2,VAPB,CTR9,WNT16,PNPLA3,SNX29,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,SNX24,CASS4,SIL1,DTD1,DDX10,SH3PXD2A,BCCIP,USP7,OLFM2,SUCLG1,ARID2,NDUFAF2,OSBPL9,NTSR1,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,FDX1,PLXNB1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,CCDC40,MYH15,AHCYL1,PRPF19,KDM3B,SOBP,SSFA2,RAB7A,ANKRD33B,CA5B,NHSL1,EIF3H,EXO1,LMBR1L,KLF4,ATG7,INTS9,EIF2B3,MUTYH,PARD3,DMGDH,HM13,ESCO1,AUH,RBM19,FOXP1,POGZ,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,LRRIQ1,MON1A,FOXN3,SMARCAD1,PLAC8L1,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,SAMD5,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBPJ,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,PRKCSH,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,CHD2,CSGALNACT2,SPAG6,ZNF646,ACADS,OSBP2,C2orf76,VSNL1,CAMSAP2,ZDHHC14,DENND4A,SON,DDX60,TMEM206,PLCXD2,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,TRRAP,SH3RF1,CCNT1,NSMCE1,ARL6IP5,LUC7L3,NRP1,TNFRSF10D,WDR66,SPOCK3,SPOCK2,ZMAT3,CADM4,C9orf78,LARS2,PRPF31,DLGAP4,MTUS1,FAM192A,TECTA,HR,SLC7A11,USPL1,LDOC1L,SCAF1,MYC,PIGG,CAV2,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,EHBP1,ANGPTL4,SLC26A11,MTR,ATP9B,CAT,ASCC3,C6orf141,MTHFD2,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,NCOR1,CNDP2,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,FLNB,RING1,NUBPL,DECR1,SLX4,ARMC6,LPIN2,SOCS6,MRPS27,SHF,TTC3,CDK12,CASP8AP2,BRD4,GON4L,PREX1,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,LARGE,IFT140,SLC4A7,CBWD1,TRAF3,XRCC4,FGFBP3,SSH2,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,DYNC2H1,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,AGPAT4,ADSL,PACS1,BMS1,KLF6,GUF1,RETSAT,DDX50,IREB2,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IMMP2L,ZNF76,LETM1,LYRM4,ATRX,RARS2,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,CEP128,DTNB,TNK2,DEAF1,SKAP2,VWCE,MINA,KSR2,COTL1,MTHFD1L,SGK2,KMT2C,ST3GAL5,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,CRCP,CSMD3,CLU,DCAF5,MTCH1,FBXO45,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ISPD,PRF1,ZCCHC7,ATP6V0D1,ZNF629,MTHFD1,MSI2,ZNF234,ELOVL6,TRA2A,ELP3,JMJD1C,ZFP14,LIG4,CORIN,SYT1,AGAP1,EXOC6,SYCP2L,BICD1,KIAA0355,FAT1,FDPS,TMEM117,CDKAL1,TBCK,PDE9A,TCF12,DMXL2,DLL4,FEZ2,TNXB,COBLL1,PBX1,SPATS2,ARSJ,PIBF1,SBDS,RIOK2,ZC3H13,RRN3,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,GNG5,MAML3,NARS2,RTN4RL2,PRAME,GRHL3,ATXN1,POU2F1,MRRF,EDEM2,UBR4,S100A16,BATF3,ARMC4,ALAD,IKZF4,HNRNPR,RNF130,NFRKB,BRD9,SMG1,TMCC1,DNAJC2,BCKDK,SUPT6H,ARL15,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,SEMA3E,MFHAS1,PEX7,STC2,LDLRAD3,ERI3,PKNOX1,MICAL3,RPS6KB2,TOP1,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,PSPC1,KDM5A,SULT4A1,SCFD2,SCMH1,PDE2A,TMEM187,EIF5B,NAALADL2,CTIF,DAGLB,WDR35,AGTPBP1,POLR1C,NFKBIB,ZSWIM6,NIT1,ASCC1,CSPP1,HLTF,NUP160,NOS1AP,AMBRA1,PCDH7,NEK6,SREBF2,NSRP1,SYN2,PMAIP1,RASSF3,RABGAP1L,PDS5B,FNIP2,ZNF148,FXN,AVEN,CDK6,PTPRM,WLS,RFX2,AKAP12,MSRB3,PLEKHM3,C10orf76,STOML2,DDX3X,BRCA2,SUPT4H1,TMEM139,FIP1L1,RBP1,MEF2C,LPP,HERC2,CARS,EP400,NHS,RSF1,SLC1A1,YARS2,ABCA7,SLC39A11,EIF2S2,KIAA1671,INTS7,CACNB2,NOC3L,PRMT5,CALN1,AGL,MAP3K12,FMNL2,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,CPT1A,MBNL2,EVI5,VPS13C,LRP1B,TASP1,CLASRP,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,DDX18,NPAS2,ACTR3,MYH9,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,ABCA12,ERI1,ZKSCAN1,CEP63,MTHFD2L,PERP,GARS,KRT7,STAMBP,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,GNG2,PES1,CDC16,IQCH,PEMT,HIPK2,WDR7,PAM,FUS,BRCC3,ANKS1A,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,XPC,SESTD1,ID2,SF3A3,WDR37,TGFB2,RSRC1,MBNL1,KRI1,NPRL2,GATC,HNRNPM,SOX6,DIS3L2,DDHD1,FAM98A,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,MRPS10,R3HDM2,FAM126B,UBE2K,PDE3B,DDX49,CASC1,ETFDH,RARS,TOE1,BAZ2B,PXDN,POLE2,ARID3B,PLPPR2,SLCO5A1,PSAP,GPAM,DOCK6,CORO2B,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TMEM132A,TTI1,BIRC2,ABL2,ARHGAP18,PHKA1,XRCC2,UBAP2L,ZNF85,RAN,ETV1,MPST,CDC37,PTPRK,FLNC,CHD9,SLC3A2,ABCC4,HARS,SKIV2L2,KATNAL1,GDPD1,MED27,COL4A3BP,NOL6,BRCA1,FLVCR1,KIF16B,PEX1,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,EEFSEC,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,MCM6,STX8,LRRC28,TRIM15,ZFP36L1,RLF,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,TLE3,BCS1L,WDR25,RNH1,ZNFX1,SUPT5H,TRAPPC6B,VAC14,ATXN7,SPAG9,FAM135A,ITPRIPL1,PALB2,DNAH17,ZNF430,HMBS,TESC,PRKAR2A,CYLD,LPCAT2,RBFOX2,PPP2R2A,RSL1D1,RNF24,RPAIN,PELP1,KDM1A,CAD,DUS4L,UBR1,ARMC5,IKBKB,ZDHHC6,HIBCH,ETF1,RNF2,ANO8,ZFP37,CORO1A,AKNAD1,PRMT3,CASP10,TMEM200A,SEC24A,WDR36,PCGF3,EVL,THSD4,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,TMEM186,USP36,BTBD11,SMAD3,RANBP2,RBBP8,TIMM17A,CLEC16A,ZNF333,ABHD3,ITGA2,TSSC1,ZNF18,NFASC,SEPT5,ATXN7L2,UNC13D,MAP3K13,ARFIP2,ZNF346,CSNK1A1,C15orf57,IQGAP2,PTPN2,SACS,ANXA7,ZNF561,CWC27,PRICKLE2,GREB1,DDX31,PCK2,FBXO31,HSD17B12,ADAMTSL3,ZNF654,DHX34,TEX14,RAP1GDS1,PEAR1,C11orf49,GPNMB,RHOT2,PIK3CB,CHCHD6,ARMC3,NEU1,CENPP,ZRANB3,POLR3G,C20orf196,SRBD1,SET,MSH3,GLG1,DNAJC12,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRKAB2,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,UBR5,AARS,MGA,GIPR,PAK1IP1,RNF111,ME1,MEIS3,CEP135,DDN,SLC38A6,SETD1B,ATG9A,NR6A1,ALDH1L2,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,SH3GL1,SKIL,HSDL2,VPS13D,GREB1L,DNAH2,SEMA3C,CCNB1IP1,ZNF598,SYNPO,PTPN14,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,ENTPD5,ASAP1,ATIC,VWDE,SLC16A9,IGF2BP1,SIK3,PTPN12,TTYH2,PLCB1,EPRS,KIDINS220,PMEPA1,ZZEF1,D2HGDH,ZBTB12,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,RTTN,PTCD2,AMOTL1,TRPM2,LIN28B,RWDD1,ZBTB37,URB2,HFM1,OLA1,KLHL18,SPATS2L,AP1B1,FOSL2,SLC25A44,LTB4R,PDE3A,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,C18orf21,RFC4,ZCCHC14,PDK1,MTIF2,WDPCP,MED16,TBC1D16,STK10,DHX57,VDR,HTR7,ZNF236,ACP1,ALKBH1,ANXA2,MDN1,KLHDC4,PDCD11,TROVE2,NCOR2,UTP14A,TTC27,TCF3,NFX1,RTN4,MON2,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,RGS17,PTRF,NISCH,PMPCA,UPF2,NLGN3,LARP4B,PLEKHG4,FAM120B,WDFY3,FZD3,KCNMA1,TBRG4,APTX,YIF1A,ZDHHC11,HELZ,HNRNPH3,MYOM2,BRWD3,RABEP1,STK4,SLC37A3,MVK,PHF3,UBN1,NF1,KIF5A,TRPM6,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,CUTC,AHCYL2,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,THADA,YLPM1,LONRF2,ZNHIT6,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,OGG1,PRKACB,TIMM50,ZBTB17,LAMA4,GPM6A,TXLNG,CMIP,SLC38A1,CAV1,SOX4,SERGEF,CDHR3,PAF1,RHOU,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,SUFU,DNAJC1,MKL2,ABCC3,GALNT10,COPS6,SLC12A7,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,MED13L,XPO7,RHBDD1,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,BANF1,SEMA3D,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,PDE4A,WBSCR22,WWC1,C11orf65,ANKRD20A4,UBAP2,MYBBP1A,SDCCAG8,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C7orf26,ASH1L,PCNT,CELSR3,MMRN2,MYO7A,ST7L,GBF1,VPS18,FARSA,BRE,CCDC50,CAMTA2,RPS6KL1,ZNF142,CPSF3,MET,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,RAB10,TPK1,RAD54B,PLIN2,HYAL3,ADNP,COPS5,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,DBF4,NSUN6,CLSTN2,PPHLN1,SFI1,MAN1A1,MRPS11,IL17RE,PRKCH,GART,DSG2,TANK,KDELC1,SHMT2,TTC17,DMRT1,MSX1,TEAD1,ANKMY2,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ALG5,MPP7,ZNF330,CUL2,MBD6,TATDN1,PREPL,ZAK,MMP16,SLC16A10 |
| 3.658e-17 | -37.85 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 14582 | 2006 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,RAD18,LRRC40,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,TPM1,VASH2,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,SAMD3,ANGPT2,MYB,NOM1,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,USP10,MAP7D1,ST6GALNAC3,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,FAM122B,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,UBL5,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,MGLL,TRMT12,ZC3H3,KIAA1549,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,POLR3E,CAMKMT,RPS6KB1,CEP170,CATSPERG,BAG1,MAPT,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,RPL22L1,PNMA1,SPTAN1,VPS37A,DDX24,LSM12,ZC3H18,LDHA,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,CXADR,MLLT10,C1orf122,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,RNFT2,MLX,ZNF358,CEP290,MBD2,NDRG4,VAPB,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,WARS2,USP49,SETD2,HAUS6,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RPS29,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,LMBR1L,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,ZNF32,RBPJ,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,S100A10,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,PRPF39,SSR4,PDCD5,C1orf50,MTUS1,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,FDFT1,EXOSC2,IFNGR2,KIAA1143,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,MTR,SLC26A11,PHF6,ATP9B,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,UROD,KIAA0232,TMEM104,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,DCXR,G6PD,MBTD1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,GUF1,SLC23A2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,IFITM2,FNBP1L,TBCK,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,CHMP2A,SNX27,DLL4,FEZ2,PSTPIP2,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,FHIT,ADCK4,ITGAX,VCL,GNG5,C6orf89,AUP1,MAML3,NARS2,NPW,ANTXR2,PRAME,GRHL3,METTL2A,ATXN1,POU2F1,MRRF,DKC1,EDEM2,UBR4,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,WDR26,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,SERINC1,WDR35,AGTPBP1,ANKRD30BL,POLR1C,NFKBIB,ZSWIM6,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,FXN,AVEN,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,ZNF266,FIS1,FIP1L1,LPP,MEF2C,HERC2,CARS,EP400,CLDN15,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,KIAA1671,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,HMGCR,PEA15,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,CEP63,LSM10,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,ARHGEF10,ATF7IP2,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,WDR37,JMJD6,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,PVRL3,ACAP3,ARHGAP1,HNRNPM,SOX6,NUDC,DIS3L2,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,R3HDM2,FAM126B,IL6R,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,POLE2,STX1A,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,XRCC2,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,FLNC,CHD9,ZNF124,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,PEX1,KIF16B,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,PGPEP1,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,PPP1R12B,ZNF430,ARHGAP12,HMBS,PRKAR2A,TESC,RNF114,KCTD7,CYLD,RBFOX2,LPCAT2,GPR143,RSL1D1,PPP2R2A,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,C15orf40,HIRIP3,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,GLTSCR2,THSD4,CPOX,MANBAL,TMEM123,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,UNC13D,MAP3K13,FAM46B,MAP1S,C14orf159,ARFIP2,ZNF346,CSNK1A1,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,ZNF561,ANXA7,CWC27,PRICKLE2,GREB1,DDX31,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,GINS3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,CHCHD6,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,ADAT2,SET,GLG1,MSH3,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,FAM122C,VPS13D,SEMA3C,DNAH2,GREB1L,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,IGF2BP1,GTF3C3,SAMD13,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,AOC2,POLA1,KIAA0586,TTYH2,PTPN12,RABAC1,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,NSF,SRRD,ZZEF1,D2HGDH,ZBTB12,RIOK3,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,PPDPF,PTCD2,AMOTL1,TRPM2,CCDC58,LIN28B,ZBTB37,URB2,RIBC2,HFM1,SPRYD7,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,CHD7,TERF2IP,FLAD1,ZNF827,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,GALK2,MED16,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,HTR7,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,ANXA2,KLHDC4,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,CA11,UTP14A,TTC27,C10orf2,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,MAD2L2,NEDD4,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,OASL,MMAA,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,SLC43A1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,RCHY1,PLOD1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,NDUFA6,OGG1,TRIM14,LONP1,PRKACB,TRIP13,TIMM50,LAMA4,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,ZNF397,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,ATXN2,SEMA3D,CCDC112,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TBXAS1,WWC1,PRDM1,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZNF706,ASH1L,PCNT,MMRN2,CELSR3,SLC5A5,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,ZNF460,TMEM14C,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,ATP8B2,C1orf174,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,H2AFJ,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,PPP1R1C,MFSD10,SFI1,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,CLDND1,TTC17,UTS2,AMOT,DMRT1,IL11RA,TEAD1,ANKMY2,PPP1R21,MARS,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,ZNF708,ALG5,MPP7,ZNF330,CUL2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10,HRH1 |
| 3.658e-17 | -37.85 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 14582 | 2006 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,RAD18,LRRC40,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,TPM1,VASH2,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,SAMD3,ANGPT2,MYB,NOM1,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,USP10,MAP7D1,ST6GALNAC3,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,FAM122B,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,UBL5,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,MGLL,TRMT12,ZC3H3,KIAA1549,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,POLR3E,CAMKMT,RPS6KB1,CEP170,CATSPERG,BAG1,MAPT,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,RPL22L1,PNMA1,SPTAN1,VPS37A,DDX24,LSM12,ZC3H18,LDHA,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,CXADR,MLLT10,C1orf122,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,LYRM2,ARID1B,SPIRE1,SUB1,RNFT2,MLX,ZNF358,CEP290,MBD2,NDRG4,VAPB,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,WARS2,USP49,SETD2,HAUS6,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RPS29,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,LMBR1L,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,ZNF32,RBPJ,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,S100A10,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,PRPF39,SSR4,PDCD5,C1orf50,MTUS1,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,FDFT1,EXOSC2,IFNGR2,KIAA1143,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,MTR,SLC26A11,PHF6,ATP9B,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,UROD,KIAA0232,TMEM104,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,DCXR,G6PD,MBTD1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,GUF1,SLC23A2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,IFITM2,FNBP1L,TBCK,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,CHMP2A,SNX27,DLL4,FEZ2,PSTPIP2,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,FHIT,ADCK4,ITGAX,VCL,GNG5,C6orf89,AUP1,MAML3,NARS2,NPW,ANTXR2,PRAME,GRHL3,METTL2A,ATXN1,POU2F1,MRRF,DKC1,EDEM2,UBR4,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,WDR26,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,SERINC1,WDR35,AGTPBP1,ANKRD30BL,POLR1C,NFKBIB,ZSWIM6,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,FXN,AVEN,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,ZNF266,FIS1,FIP1L1,LPP,MEF2C,HERC2,CARS,EP400,CLDN15,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,KIAA1671,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,HMGCR,PEA15,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,CEP63,LSM10,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,ARHGEF10,ATF7IP2,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,WDR37,JMJD6,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,PVRL3,ACAP3,ARHGAP1,HNRNPM,SOX6,NUDC,DIS3L2,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,R3HDM2,FAM126B,IL6R,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,POLE2,STX1A,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,XRCC2,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,FLNC,CHD9,ZNF124,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,PEX1,KIF16B,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,PGPEP1,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,PPP1R12B,ZNF430,ARHGAP12,HMBS,PRKAR2A,TESC,RNF114,KCTD7,CYLD,RBFOX2,LPCAT2,GPR143,RSL1D1,PPP2R2A,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,C15orf40,HIRIP3,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,GLTSCR2,THSD4,CPOX,MANBAL,TMEM123,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,UNC13D,MAP3K13,FAM46B,MAP1S,C14orf159,ARFIP2,ZNF346,CSNK1A1,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,ZNF561,ANXA7,CWC27,PRICKLE2,GREB1,DDX31,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,GINS3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,CHCHD6,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,ADAT2,SET,GLG1,MSH3,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,FAM122C,VPS13D,SEMA3C,DNAH2,GREB1L,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,IGF2BP1,GTF3C3,SAMD13,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,AOC2,POLA1,KIAA0586,TTYH2,PTPN12,RABAC1,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,NSF,SRRD,ZZEF1,D2HGDH,ZBTB12,RIOK3,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,PPDPF,PTCD2,AMOTL1,TRPM2,CCDC58,LIN28B,ZBTB37,URB2,RIBC2,HFM1,SPRYD7,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,CHD7,TERF2IP,FLAD1,ZNF827,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,GALK2,MED16,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,HTR7,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,ANXA2,KLHDC4,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,CA11,UTP14A,TTC27,C10orf2,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,MAD2L2,NEDD4,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,OASL,MMAA,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,SLC43A1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,RCHY1,PLOD1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,NDUFA6,OGG1,TRIM14,LONP1,PRKACB,TRIP13,TIMM50,LAMA4,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,ZNF397,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,ATXN2,SEMA3D,CCDC112,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TBXAS1,WWC1,PRDM1,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZNF706,ASH1L,PCNT,MMRN2,CELSR3,SLC5A5,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,ZNF460,TMEM14C,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,ATP8B2,C1orf174,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,H2AFJ,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,PPP1R1C,MFSD10,SFI1,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,CLDND1,TTC17,UTS2,AMOT,DMRT1,IL11RA,TEAD1,ANKMY2,PPP1R21,MARS,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,ZNF708,ALG5,MPP7,ZNF330,CUL2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10,HRH1 |
| 3.733e-17 | -37.83 | nucleoplasm part | cellular component | GO:0044451 | 698 | 168 | 17570 | 2233 |
THOC5,TRIM16,UBN1,KMT2E,ATRX,PPARGC1B,TFIP11,PLRG1,RCHY1,CSNK2A1,CCNL2,MGA,SKI,SRSF2,NEK6,PHF5A,ZFHX3,NSRP1,YLPM1,KANSL1,UBAP2L,POLR3B,POLE3,SRRM2,ZMYM2,OGG1,TIMM50,AEBP2,SETD1B,MED27,TCEB3,SUMO3,HDAC8,SUPT20H,KMT2C,SON,LSG1,SPOP,TAF9B,DDX3X,PAF1,GEMIN5,SKIL,TRRAP,EIF4ENIF1,SUPT4H1,CCNT1,CHD3,FAM206A,LUC7L3,PQBP1,CRCP,PRPF4,FIP1L1,ZC3H8,MEF2C,WDR75,EP400,PRPF31,TAF1,AK6,MED13L,CDC73,CHD5,ELL,HR,USPL1,INTS7,MBD2,GTF2H1,MED24,CTR9,ICE2,GEMIN4,NOC3L,PRMT5,NRIP1,CPSF3L,GATAD2B,GTF2H3,WDR61,RREB1,ELP3,NELFA,SUPT5H,PLCB1,TRIM37,TCF7L2,PRPF40B,ATXN7,GTF2A1,HIF1A,CDK9,INTS5,MED15,TBPL1,SENP3,TBL1X,NCOR1,WDR33,USP7,SART1,RPAIN,PELP1,RING1,ZC3H13,WAC,INTS12,RNF2,CPSF3,KMT2A,ZC3H3,CDK12,LSM10,CASP8AP2,MAML3,SAP30,PRPF19,KAT8,KMT2D,BRD4,ATXN1,SATB2,MED16,PNN,DKC1,TAF2,DNTTIP1,ELP2,HIPK2,NSMCE2,POLR3E,ARNTL,INTS9,MED20,NOLC1,YEATS2,NCOR2,SHQ1,SF3A3,MED18,TRIM22,IKBKAP,CSNK1A1,RSRC1,TADA3,SNW1,POLR3D,TAF3,FBL,HNRNPM,CLK2,APEX1,WDFY3,PSPC1,TOP3A,MEN1,NOP58,POLR3A,POLR2A,POLR3G,RPA1,RERE,TOE1,TAF4,TAF12,POLR1C,KAT6A |
| 5.461e-17 | -37.45 | PILON_KLF1_TARGETS_DN | MSigDB lists | PILON_KLF1_TARGETS_DN | 1896 | 364 | 17758 | 2279 |
PTP4A1,MYCBP2,TMEM109,GYG1,SYNJ1,EXOC1,S100A10,THAP4,RABGAP1L,AP1M1,RNF111,FNIP2,FUT11,CDK6,CSGALNACT2,TBC1D8,EIF4E3,NRAS,RNMT,C2orf76,EHMT1,TCEB3,AKAP12,WDHD1,MCL1,SON,RBM28,SPOP,SKIL,AHNAK,HSDL2,RAD18,LSM14A,LRRC40,SYNGR2,RIOK1,BMI1,MEF2C,EP400,CLDN15,ANKRD17,CCDC53,KHDRBS1,PITPNM1,MTUS1,IGF2BP3,SH2B3,RSPRY1,FKBP1A,C6orf48,INTS7,USPL1,ATIC,MYC,NOC3L,CCDC88C,PLEKHA2,LPCAT1,AGL,SERBP1,MYB,SIK3,IFRD1,STAG1,PRIM2,RREB1,RAP1GAP2,RAP1B,PTPN12,ARID1A,ABCF1,SEC31A,KIDINS220,GTF2A1,ZZEF1,CDK9,LEMD3,RIOK3,PURB,GPN1,PEX13,UMPS,NCOR1,HS2ST1,VMA21,SPRED2,RWDD1,ACTR3,NECAP1,ISG20L2,SAFB2,STAM,NOP56,RPP30,CHD7,PRKD3,UCHL5,SETD5,PYCRL,GLYR1,SOCS6,DTNBP1,INTS12,SSBP1,CMPK1,PXK,NAA35,PERP,SAP30,MPP6,PDK1,MTIF2,LGALS1,PCMT1,PREX1,MARCH6,MEF2D,SETD7,FKBP3,ZBTB25,GNG2,FBXL5,BAZ1A,ARHGAP21,SMARCC1,ZNF236,POLR3E,ALKBH1,IFT140,TRMT2A,SLC4A7,TRAF3,NOLC1,METTL2B,ANKS1A,HMGA2,SSH2,NCOR2,TTC27,ZNF280C,ID2,SF3A3,ATG2B,IKBKAP,RNASEH2B,INPP1,SFR1,ATXN7L1,SNW1,LTN1,RDX,PTGS1,CELF1,HNRNPM,TSHZ1,APEX1,PSAT1,USP42,ZC3H18,TMEM126A,NXN,IL6R,KLF6,PDE3B,ANXA1,YIF1A,TOE1,POLE2,ORC5,RNF138,SVIL,NDUFS5,APAF1,PGAM5,MTMR1,ANAPC4,GPATCH4,STK4,KAT6A,FEM1C,EIF3C,PPARGC1B,POLR1A,CERS5,TTI1,COX10,GIT2,SCAF8,FRRS1,SLC30A7,SMARCB1,ANAPC1,RAP1A,DHX33,ATG3,ZNHIT6,NCKIPSD,METTL8,RAN,TRIP13,VPS13B,SRPK2,TMPO,ELOF1,TRIM13,AEBP2,ABCC4,SKAP2,SLC38A1,CDK4,HSPA5,MINA,COL4A3BP,SUMO3,ATG12,PSMG1,MARCKSL1,PITPNB,COTL1,SOX4,CRYBG3,MGST1,MLLT10,YTHDF2,HPRT1,TMCO1,EIF4ENIF1,SUFU,TP53BP1,FAM206A,ADAM9,TNRC6A,SEPHS2,CTU2,FBXO45,MCM6,AK2,FOXO1,ZCCHC8,ALG8,HSD17B10,MED13L,SMG7,XPO7,PHGDH,ARID1B,TOX4,RNF141,CEP164,SUB1,SIPA1L3,TIMELESS,GTF2H1,POLR1E,NAA38,CAMKK2,PPAT,TLE3,TRA2A,XPO5,UTP15,WBSCR22,MAPK1IP1L,EIF2A,UBE2E1,PGD,MGAT2,PWP1,KIAA0355,INTS5,TBL1X,PTP4A2,ZBTB24,USP7,NDUFA5,ZNF706,CYLD,ARID2,FAM207A,OSBPL9,MYO7A,PPP2R2A,RIPK1,PAG1,CAD,ANKRD13A,ZNF608,CCDC50,DNAJB6,ZDHHC6,IKBKB,SLC38A2,RNF2,CORO1A,CPSF3,TSPAN14,PRMT3,C6orf89,PRPF19,ACSL5,WDR36,ANTXR2,ARHGAP17,FAM172A,PARP2,TMEM123,VIM,AKAP13,KPNA3,HNRNPR,ARNTL,RNF130,MED20,BRD9,TSPAN5,TMCC1,YDJC,ARL15,DBF4,PPHLN1,ATF7IP,FOXP1,PIP4K2A,BZW2,POGZ,IQGAP2,PTPN2,ADH5,PEX7,GART,KDELC1,SELT,CLDND1,POLR1B,TTC17,LDLRAD3,CD44,C12orf4,KDM6B,GPHN,GINS3,FOXN3,PPP1R21,PSMC3IP,TPM4,TOP3A,RAP1GDS1,PDE2A,ZNF407,TMEM175,POLR3A,RERE,ALG5,ZNF330,AGTPBP1,SET,TAF4,EIF2S1,RWDD2B,MBD6,RBPJ,ZAK,XPO6,ZSWIM6 |
| 8.074e-17 | -37.06 | LEE_BMP2_TARGETS_DN | MSigDB lists | LEE_BMP2_TARGETS_DN | 840 | 193 | 17758 | 2279 |
SRM,WDR74,PRKAB2,POLR1A,NAT10,ENAH,NLE1,COX10,NUP160,CIAPIN1,PHF5A,DHX33,ZNF148,ME1,RAN,TRIP13,SEH1L,SKIV2L2,GNL3,NOL8,HSPA5,GMFB,WDHD1,BRCA1,MTHFD1L,MCM2,FOXRED1,FLVCR1,ODC1,MAK16,CLNS1A,DOT1L,GEMIN5,SLC7A1,RUNX1,ZC3H8,NMD3,WDR75,OXNAD1,MCM6,AK2,MEX3A,SMAD7,PHGDH,TIMM10,CDC73,YARS2,NAMPT,CHN1,DDX56,EIF2S2,MCM5,ATIC,GEMIN4,NOC3L,POLR1E,PRPS1,PPA1,CPSF3L,MTHFD1,HMGCR,NT5E,NAA38,IFRD1,PPAT,TRA2A,XPO5,HAUS6,UTP15,USP10,USP46,PGD,POP1,PWP1,MGAT2,TSR1,ATAD5,MTHFD2,MYBBP1A,KPNA1,SYNCRIP,FSCN1,HK2,SLC16A1,SQLE,PTRH2,PURB,UMPS,MB21D2,BCCIP,VMA21,MPI,ID1,DDX18,URB2,SPRYD7,NECAP1,ISG20L2,NUP43,PTPRG,URB1,NOP56,METTL16,RPP30,CAD,RRN3,PUS3,MPHOSPH10,ASNS,IDI1,DUS4L,NVL,UCHL5,ETF1,PRMT3,CASP8AP2,HTRA2,NARS2,WDR36,NARS,EIF3J,PCMT1,NLN,PNN,DKC1,GSTCD,SLC35D1,ENC1,FKBP3,MAT2A,TAF2,BAZ1A,EXO1,TIMM17A,DNAJA3,ACP1,FKBP5,SRFBP1,RPS6KB1,MDN1,HEATR1,EIF2B3,NOLC1,PDCD11,TMEM33,YDJC,DNAJC2,MCM10,DNAJA4,SHQ1,B4GALT5,DBF4,JMJD6,OPA1,RBM19,PHLDA2,DCTPP1,SACS,GART,CTNNBL1,SUV39H2,NOP16,PVRL3,TANK,ACOT11,PMPCA,SHMT2,POLR1B,PLEKHG4,SAMD4A,NAV3,FAM98A,APEX1,PSAT1,LSM12,PSPC1,WDR18,PSMC3IP,FRA10AC1,LDHA,MARS,PDE3B,NOP58,RPA1,RETSAT,NOL10,POLE2,TBX3,RNF138,CSRNP1,EIF2S1,AEN,PGAM5 |
| 1.102e-16 | -36.74 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 13367 | 1867 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,SLC6A8,ZNF44,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,MSANTD2,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,UPP1,AP4B1,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,SLC25A26,ZNF532,BANP,TMEM63C,TRIO,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,SDSL,RAB11FIP4,GTF2H2C,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,FAM122B,NUP43,ST3GAL6,LCLAT1,CBWD5,RPGRIP1L,NDUFB3,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,EIF3J,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,DSP,VPS53,MAT2A,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,POLR3E,CAMKMT,HOXA3,RPS6KB1,CEP170,METTL2B,BAG1,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,RNASEH2B,PSMF1,SNW1,PSMG4,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,TTPAL,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,SRD5A3,AEN,BMP4,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,MIOS,PPARG,CDK4,ANK2,HSPA5,SUMO3,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,BSN,HPRT1,TCF7L1,LSS,INSIG1,CHD3,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,FOXO1,CLK1,ITFG1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,LYRM2,SUB1,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,WNT16,PNPLA3,LRSAM1,SNX29,NIPSNAP1,WARS2,IFT43,USP49,HAUS6,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,PAG1,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,TJAP1,EXO1,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,HM13,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,POGZ,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,SMARCAD1,C22orf34,ABCF2,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,S100A10,ZFYVE28,CHD2,SPAG6,CSGALNACT2,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,LARS2,PRPF31,ST6GAL1,DLGAP4,TATDN3,SSR4,PDCD5,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,RREB1,PRIM2,ANAPC13,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ZNF850,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,CPT1C,HS2ST1,SYT17,BIRC6,UROD,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,SNCA,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,MID1,SSH2,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,DYNC2H1,CELF1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,PACS1,BMS1,KLF6,SLC23A2,RETSAT,DDX50,IREB2,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,LYRM4,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,SIRT6,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,TIMM44,YTHDF2,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,PCSK7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,ISPD,CCDC124,ZCCHC7,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,BICD1,FSCN1,KIAA0355,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,TBCK,PDE9A,TCF12,DMXL2,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,PRAME,GRHL3,ATXN1,MRRF,DKC1,EDEM2,UBR4,BATF3,ARMC4,ALAD,KPNA3,DUS3L,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,ARC,RNF130,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,MED18,SEMA3E,ENOX1,PIP4K2A,BMP6,GFM2,MFHAS1,FAM49A,PEX7,SCN1B,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,NFKBIB,ZSWIM6,GNB3,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,AMBRA1,TOM1L1,PCDH7,C1orf159,SREBF2,NSRP1,SYN2,PMAIP1,RABGAP1L,RASSF3,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,SUPT4H1,ZNF266,FIS1,FIP1L1,LPP,MEF2C,HERC2,CARS,EP400,CLDN15,KHDRBS1,NHS,RSF1,KCNJ14,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,C6orf48,EIF2S2,KIAA1671,INTS7,MCM5,CACNB2,ZNF326,NOC3L,ANP32B,COQ3,AGL,MAP3K12,TOMM34,FMNL2,SERBP1,HMGCR,PEA15,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,CEP63,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,LGALS1,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,SF3A3,WDR37,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,GATC,PVRL3,ARHGAP1,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,ETFDH,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,ZNF124,SLC3A2,ABCC4,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,KIF16B,PEX1,GLS,MSRA,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,MEX3A,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,WDR25,RNH1,SUPT5H,TRAPPC6B,VAC14,PGD,PWP1,NAP1L5,ITPRIPL1,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,HMBS,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,GPR143,RSL1D1,PPP2R2A,LPCAT3,RPAIN,DENR,CAD,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,MANBAL,TMEM123,SLC35F2,AKAP13,NUP214,ARL5B,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,ZNF18,PUS1,SEPT5,ZNF589,PPIL3,AP2S1,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,MAP1S,C14orf159,ARFIP2,ZNF346,CSNK1A1,RMI1,BZW2,IQGAP2,PTPN2,FAM50A,SACS,ZNF561,ANXA7,CWC27,PRICKLE2,DDX31,SELT,CD44,PCK2,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,SRBD1,ZBTB8OS,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,POLB,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,IKBIP,AARS,UBR5,MGA,GIPR,RPS16,RNF111,VPS52,PAK1IP1,ME1,PRADC1,CEP135,MEIS3,SEH1L,TBC1D8,SLC38A6,DPF3,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,ASAP1,COPS3,ATIC,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,SYNGAP1,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,SERF2,PMEPA1,SRRD,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,ZBTB37,URB2,RIBC2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,AP1B1,SLC25A44,FOSL2,LTB4R,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,GALK2,MED16,TBC1D16,POLG2,STK10,DHX57,CPED1,VDR,HTR7,YIPF2,ZNF236,ACP1,ALKBH1,ANXA2,KLHDC4,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,SCAMP3,UTP14A,TTC27,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,FZD3,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,ECH1,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,MKL2,PQBP1,BBIP1,ABCC3,GALNT10,ZNF397,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,PIGN,CHST11,FN1,SEC24D,TAF1,ALG8,MED13L,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BUD31,CCDC112,SEMA3D,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,KRT20,PDE4A,TSTA3,WBSCR22,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,C19orf70,DNAH14,UBAP2,ATAD5,MYBBP1A,SDCCAG8,RRAGA,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,VPS18,FARSA,BRE,LYPLAL1,CCDC50,RPS6KL1,SLC38A2,MET,CPSF3,TSPAN14,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,ADNP,COPS5,SRFBP1,SLC25A11,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,TTC17,UTS2,DMRT1,SLC25A1,PAQR6,MSX1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,ZNF708,ALG5,MPP7,ZNF330,CUL2,NCBP2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10 |
| 1.202e-16 | -36.66 | prostate-carcinoma-adenocarcinoma | COSMIC cancer mutations | prostate-carcinoma-adenocarcinoma | 13006 | 1825 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,SRRM2,PPM1K,CCDC57,HMBOX1,NRAS,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,SLC25A26,ZNF532,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,USP46,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,UBL5,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,PEG10,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,FAM171A2,PCNXL2,MEF2D,SLC35D1,DSP,VPS53,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,RPS6KB1,CEP170,METTL2B,CATSPERG,MAPT,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,SAMD4A,RPL22L1,SPTAN1,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,LAMA2,KCNH2,KRTCAP2,DLST,CRYBG3,LSG1,CXADR,BSN,TCF7L1,LSS,INSIG1,CHD3,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,ARID1B,SPIRE1,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,OBSCN,MAPK1IP1L,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,SART1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,NTSR1,SLC2A1,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,TLCD1,AKAP8L,RAB7A,ANKRD33B,CA5B,NHSL1,EIF3H,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,HM13,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,POGZ,SLC25A20,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,LRRIQ1,MON1A,FOXN3,SMARCAD1,C22orf34,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,USP20,RBM26,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,TMEM206,PLCXD2,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,LUC7L3,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,RFXAP,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,ST6GAL1,DLGAP4,CENPB,TATDN3,PDCD5,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,CNOT4,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,SLC26A11,MTR,PHF6,ATP9B,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ASNS,PPID,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,C1orf228,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,ERC1,SNCA,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,LARGE,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,GIGYF2,FAM8A1,SFR1,ABL1,NEBL,ELP5,SDCBP2,DYNC2H1,CELF1,S100A14,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,ZFYVE1,AGPAT4,ADSL,PACS1,BMS1,GUF1,SLC23A2,RETSAT,DDX50,IREB2,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,IMMP2L,LETM1,LYRM4,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,ISPD,CCDC124,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,FNBP1L,TBCK,PDE9A,NR2C2AP,DMXL2,TCF12,CHMP2A,FEZ2,TMEM183A,TNXB,PIGH,SMARCA4,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,PRAME,GRHL3,ATXN1,POU2F1,MRRF,DKC1,EDEM2,UBR4,BATF3,ARMC4,ALAD,KPNA3,DUS3L,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,SCMH1,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NFKBIB,ZSWIM6,NIT1,GNB3,ASCC1,CSPP1,HLTF,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,RABGAP1L,FAAH2,RASSF3,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,AKAP12,PLEKHM3,MCL1,DCUN1D5,C10orf76,SLC50A1,STOML2,DLEU1,DDX3X,BRCA2,SUPT4H1,ZNF266,TMEM139,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,INTS7,MCM5,CACNB2,ZNF326,NOC3L,ANP32B,PRMT5,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,SMARCD3,CPT1A,ONECUT2,MBNL2,EVI5,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,HSPA1A,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,GSTA4,CEP63,TMEM136,PERP,GARS,KRT7,STAMBP,ARHGEF10,LGALS1,ADAM32,TTC28,FKBP3,FGFR1,PDE8B,GNG2,PES1,IQCH,CDC16,PEMT,HIPK2,WDR7,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,SF3A3,WDR37,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,ARHGAP1,HNRNPM,SOX6,NUDC,DIS3L2,DDHD1,C21orf58,FAM98A,FBXO17,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,MRPS10,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,ETFDH,RARS,TOE1,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,PLPPR2,SLCO5A1,PTPN4,PSAP,GPAM,IGBP1,DOCK6,CORO2B,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,FLNC,CHD9,ZNF124,SLC3A2,ABCC4,HARS,BAZ2A,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,PEX1,KIF16B,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,ITPRIP,MEX3A,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,ATXN7,FAM135A,ITPRIPL1,SPAG9,SYNCRIP,PALB2,DNAH17,PPP1R12B,ZNF430,ARHGAP12,HMBS,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,GPR143,RSL1D1,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,UBR1,ARMC5,FSIP2,DNAJB6,C15orf40,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,SMAD3,RANBP2,RBBP8,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,PRRT3,NFASC,ZNF589,PPIL3,PKIB,UNC13D,MIF4GD,MAP3K13,MAP1S,C14orf159,ZNF346,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,NDUFV1,SACS,ZNF561,ANXA7,CWC27,IFIT5,PRICKLE2,GREB1,DDX31,SELT,CD44,PCK2,HSD17B12,FAM71E1,ADAMTSL3,GINS3,ZMYM5,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,TPD52L2,C20orf196,SRBD1,ADAT2,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRDX6,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,AARS,UBR5,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,SAP30BP,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ENTPD5,ASAP1,COPS3,VWDE,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,AOC2,KIAA0586,PTPN12,TTYH2,RABAC1,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,PMEPA1,SRRD,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,PEX13,UMPS,MACROD1,MAP2K4,ZFHX2,RTTN,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,ZBTB37,URB2,RIBC2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,TRIM66,PDE3A,PAIP2,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,PNPLA4,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,GALK2,MED16,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,HTR7,YIPF2,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,TROVE2,NCOR2,CA11,UTP14A,TTC27,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,EXOSC4,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,PFKFB4,WDFY3,C19orf43,FZD3,KCNMA1,TBRG4,APTX,OASL,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,TRIP13,TIMM50,LAMA4,ZBTB17,GPM6A,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,ZSCAN2,TCTN1,SERGEF,CDHR3,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,DNAJC1,RLTPR,MKL2,BBIP1,ABCC3,GALNT10,COPS6,ZNF397,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,ATXN2,BUD31,CCDC112,SEMA3D,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,TSTA3,WBSCR22,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,EP400NL,SDCCAG8,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,CSTA,UBTD2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,DBF4,H2AFJ,NSUN6,CLSTN2,PPHLN1,CCDC7,PPP1R1C,SFI1,HDDC2,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,SHMT2,TTC17,DMRT1,TEAD1,ANKMY2,PPP1R21,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,MPP7,CUL2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10 |
| 2.052e-16 | -36.12 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | 2204 | 408 | 17775 | 2278 |
ARHGAP26,CDCP1,NAT10,SBF2,NOS1AP,PCDH7,PDZD2,ZFHX3,ZFYVE28,SYN2,RABGAP1L,ME1,AVEN,CDK6,HMBOX1,NRAS,PTPRM,AP4B1,CUX1,DCUN1D5,SON,FOXRED1,DDX60,GNAI1,OSBPL1A,DDX3X,BRCA2,HSDL2,BDH2,VPS13D,SEMA3C,GREB1L,ZNF532,SPOCK2,ZMAT3,PTPN14,EFNB2,DROSHA,ST6GAL1,TRIO,NHS,OPHN1,PID1,PARN,ANXA10,PRKCE,RBM20,UBE3A,TSPAN2,SLC7A11,NOVA2,USPL1,INTS7,ASAP1,MYC,LPCAT1,AGL,FMNL2,SAMD3,HMGCR,FDFT1,SIK3,STAG1,KCNQ3,PRIM2,MYO10,RB1CC1,PRDM16,PCCA,ARID5B,RAPGEF4,TYW1,RAP1GAP2,RYR2,TTYH2,PTPN12,USP10,ST6GALNAC3,ARID1A,PLCB1,MTR,ATP9B,LRP1B,NME7,PMEPA1,VCAN,SPEN,ZNF160,NCOR1,MACROD1,DHCR7,PDLIM5,MB21D2,ARHGAP10,COG5,HS2ST1,RTTN,SPRED2,RAB11FIP4,SYT17,DNM3,TRPM2,LIN28B,DDX18,NPAS2,C16orf45,ACTR3,PDK4,VTI1A,OLA1,MYH9,SPATS2L,PTPRG,AP1B1,SAFB2,PDE3A,CHD7,CD96,ABCA12,TBC1D22A,WAC,DTNBP1,NBEA,TTC3,PLEKHA4,ZC3H3,DENND1A,LYST,MALL,PDK1,MTIF2,WDPCP,SLCO6A1,PCNXL2,SATB2,TTC28,TBC1D16,ERC1,PDE8B,SNCA,ZFAND3,ARHGAP21,KDM4B,ASTN2,NSMCE2,PEMT,CAMKMT,WDR7,LARGE,IFT140,KLHDC4,PDCD11,LAMA5,TROVE2,MORC2,SSH2,BRAF,B4GALT5,TCF3,FARS2,MYNN,MON2,RSRC1,FOXO3,REEP5,MBNL1,NEDD4,TAF3,PVRL3,RDX,DYNC2H1,C15orf41,SAMD4A,SOX6,DIS3L2,SLC40A1,TTLL5,CLYBL,WDFY3,POLK,ARHGAP39,NXN,PPIP5K2,PDE3B,CASC1,CCDC150,TOE1,PXDN,HELZ,ORC5,ATM,SORCS2,ADK,IMMP2L,SLC37A3,LETM1,RBM33,PPARGC1B,SLC25A21,FAM13A,COX10,SNAPC4,CUTC,AHCYL2,SMARCB1,RTN1,ZNF804A,SRSF2,ARHGAP18,CNIH3,THADA,LONRF2,JAZF1,TRIML2,B3GNTL1,POLR3B,ZMYM2,CEP128,CDC37,VPS13B,FAM184A,DSC3,LAMA4,DTNB,CHD9,GPM6A,SKAP2,ABCC4,ZNF680,CMIP,PPARG,KATNAL1,ANK2,TFPI,KSR2,PSMG1,LAMA2,ZNF91,SERGEF,CXADR,KIF16B,GLS,TMEM132B,TCF7L1,EPN2,MSRA,HLCS,SUFU,DNAJC1,EEFSEC,TECPR2,RAD51B,CTAGE5,SGSM2,CSMD3,ABCC3,PPP3CC,MAGI1,RNF214,DCAF5,USP15,SLC12A7,CHST11,FOXO1,STX8,FN1,ZCCHC8,ITFG1,STXBP6,MAPK8IP3,MED13L,RNF141,KIAA1958,PDE10A,ISPD,SEMA3D,GMDS,ZCCHC7,MTHFD1,TRAPPC9,CRADD,CORIN,SYT1,AGAP1,DNAH14,NR2F1,VAC14,GRIK4,KIAA0355,FAT1,SDCCAG8,EXOC4,SNX24,TMEM117,SIL1,CDKAL1,DTD1,KIAA1328,ARHGAP12,DDX10,SH3PXD2A,TBCK,PAPD4,SLC5A5,SMARCA4,COBLL1,SSBP2,PIBF1,RADIL,DDX60L,URB1,BRE,SOCS1,CCDC50,NUP133,DNAJB6,SNTG2,HIBCH,FHIT,MET,VCL,PRMT3,CASP10,NARS2,PCGF3,COL5A2,FAM172A,THSD4,SLC35F2,AKAP13,NHSL1,UBR4,EIF3H,TPK1,SMAD3,ARMC4,ADNP,CLEC16A,INTS9,TSSC1,NFASC,RNF130,AP2S1,SMG1,PARD3,TMCC1,ESCO1,MAP3K13,DYM,PDE4B,NSUN6,CLSTN2,IGF2BP2,SEMA3E,PPP1R1C,CSNK1A1,FOXP1,BMP6,PIP4K2A,IQGAP2,IL17RE,PRKCH,PTPN2,GART,CTNNBL1,TANK,PRICKLE2,DDX31,LDLRAD3,DMRT1,ADAMTSL3,FGF2,CRIM1,ZMYM5,SULT4A1,SCFD2,ASAP3,RAP1GDS1,FERMT2,ARHGEF12,PALLD,ZNF407,NAALADL2,CHCHD6,RERE,MKX,CENPP,CTIF,ZRANB3,ZNF708,SAMD5,C20orf196,DSC2,MPP7,AGTPBP1,TAF4,TBX3,GLG1,BCAS3,MSH3,USP20,ITGB4,RPS6KC1,KIF1B,MMP16,MIPOL1,LMBRD2,ZSWIM6 |
| 2.052e-16 | -36.12 | Burkitt_lymphoma | COSMIC cancer mutations | Burkitt_lymphoma | 2204 | 408 | 17775 | 2278 |
ARHGAP26,CDCP1,NAT10,SBF2,NOS1AP,PCDH7,PDZD2,ZFHX3,ZFYVE28,SYN2,RABGAP1L,ME1,AVEN,CDK6,HMBOX1,NRAS,PTPRM,AP4B1,CUX1,DCUN1D5,SON,FOXRED1,DDX60,GNAI1,OSBPL1A,DDX3X,BRCA2,HSDL2,BDH2,VPS13D,SEMA3C,GREB1L,ZNF532,SPOCK2,ZMAT3,PTPN14,EFNB2,DROSHA,ST6GAL1,TRIO,NHS,OPHN1,PID1,PARN,ANXA10,PRKCE,RBM20,UBE3A,TSPAN2,SLC7A11,NOVA2,USPL1,INTS7,ASAP1,MYC,LPCAT1,AGL,FMNL2,SAMD3,HMGCR,FDFT1,SIK3,STAG1,KCNQ3,PRIM2,MYO10,RB1CC1,PRDM16,PCCA,ARID5B,RAPGEF4,TYW1,RAP1GAP2,RYR2,TTYH2,PTPN12,USP10,ST6GALNAC3,ARID1A,PLCB1,MTR,ATP9B,LRP1B,NME7,PMEPA1,VCAN,SPEN,ZNF160,NCOR1,MACROD1,DHCR7,PDLIM5,MB21D2,ARHGAP10,COG5,HS2ST1,RTTN,SPRED2,RAB11FIP4,SYT17,DNM3,TRPM2,LIN28B,DDX18,NPAS2,C16orf45,ACTR3,PDK4,VTI1A,OLA1,MYH9,SPATS2L,PTPRG,AP1B1,SAFB2,PDE3A,CHD7,CD96,ABCA12,TBC1D22A,WAC,DTNBP1,NBEA,TTC3,PLEKHA4,ZC3H3,DENND1A,LYST,MALL,PDK1,MTIF2,WDPCP,SLCO6A1,PCNXL2,SATB2,TTC28,TBC1D16,ERC1,PDE8B,SNCA,ZFAND3,ARHGAP21,KDM4B,ASTN2,NSMCE2,PEMT,CAMKMT,WDR7,LARGE,IFT140,KLHDC4,PDCD11,LAMA5,TROVE2,MORC2,SSH2,BRAF,B4GALT5,TCF3,FARS2,MYNN,MON2,RSRC1,FOXO3,REEP5,MBNL1,NEDD4,TAF3,PVRL3,RDX,DYNC2H1,C15orf41,SAMD4A,SOX6,DIS3L2,SLC40A1,TTLL5,CLYBL,WDFY3,POLK,ARHGAP39,NXN,PPIP5K2,PDE3B,CASC1,CCDC150,TOE1,PXDN,HELZ,ORC5,ATM,SORCS2,ADK,IMMP2L,SLC37A3,LETM1,RBM33,PPARGC1B,SLC25A21,FAM13A,COX10,SNAPC4,CUTC,AHCYL2,SMARCB1,RTN1,ZNF804A,SRSF2,ARHGAP18,CNIH3,THADA,LONRF2,JAZF1,TRIML2,B3GNTL1,POLR3B,ZMYM2,CEP128,CDC37,VPS13B,FAM184A,DSC3,LAMA4,DTNB,CHD9,GPM6A,SKAP2,ABCC4,ZNF680,CMIP,PPARG,KATNAL1,ANK2,TFPI,KSR2,PSMG1,LAMA2,ZNF91,SERGEF,CXADR,KIF16B,GLS,TMEM132B,TCF7L1,EPN2,MSRA,HLCS,SUFU,DNAJC1,EEFSEC,TECPR2,RAD51B,CTAGE5,SGSM2,CSMD3,ABCC3,PPP3CC,MAGI1,RNF214,DCAF5,USP15,SLC12A7,CHST11,FOXO1,STX8,FN1,ZCCHC8,ITFG1,STXBP6,MAPK8IP3,MED13L,RNF141,KIAA1958,PDE10A,ISPD,SEMA3D,GMDS,ZCCHC7,MTHFD1,TRAPPC9,CRADD,CORIN,SYT1,AGAP1,DNAH14,NR2F1,VAC14,GRIK4,KIAA0355,FAT1,SDCCAG8,EXOC4,SNX24,TMEM117,SIL1,CDKAL1,DTD1,KIAA1328,ARHGAP12,DDX10,SH3PXD2A,TBCK,PAPD4,SLC5A5,SMARCA4,COBLL1,SSBP2,PIBF1,RADIL,DDX60L,URB1,BRE,SOCS1,CCDC50,NUP133,DNAJB6,SNTG2,HIBCH,FHIT,MET,VCL,PRMT3,CASP10,NARS2,PCGF3,COL5A2,FAM172A,THSD4,SLC35F2,AKAP13,NHSL1,UBR4,EIF3H,TPK1,SMAD3,ARMC4,ADNP,CLEC16A,INTS9,TSSC1,NFASC,RNF130,AP2S1,SMG1,PARD3,TMCC1,ESCO1,MAP3K13,DYM,PDE4B,NSUN6,CLSTN2,IGF2BP2,SEMA3E,PPP1R1C,CSNK1A1,FOXP1,BMP6,PIP4K2A,IQGAP2,IL17RE,PRKCH,PTPN2,GART,CTNNBL1,TANK,PRICKLE2,DDX31,LDLRAD3,DMRT1,ADAMTSL3,FGF2,CRIM1,ZMYM5,SULT4A1,SCFD2,ASAP3,RAP1GDS1,FERMT2,ARHGEF12,PALLD,ZNF407,NAALADL2,CHCHD6,RERE,MKX,CENPP,CTIF,ZRANB3,ZNF708,SAMD5,C20orf196,DSC2,MPP7,AGTPBP1,TAF4,TBX3,GLG1,BCAS3,MSH3,USP20,ITGB4,RPS6KC1,KIF1B,MMP16,MIPOL1,LMBRD2,ZSWIM6 |
| 2.093e-16 | -36.10 | lymphoid_neoplasm | COSMIC cancer mutations | lymphoid_neoplasm | 12854 | 1806 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,NAT10,MKS1,SBF2,HMOX2,ABHD6,LPAR3,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,UPP1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,RAD18,LRRC40,SYNGR2,BDH2,MPV17,RIOK1,RUNX1,TPM1,VASH2,ZNF532,SLC25A26,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,RSPRY1,CHN1,RBM20,CNST,UBE3A,DHX37,APLF,WDR60,MED24,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,ZNF675,IFRD1,ALG6,WDR61,STAG1,KCNQ3,ARID5B,IDH3G,TYW1,USP10,ST6GALNAC3,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,ARHGAP10,RAB11FIP4,PAFAH1B1,C16orf45,VTI1A,DDR2,CD99L2,NUP43,ST3GAL6,LCLAT1,MCM9,UBL5,RPGRIP1L,CD96,ESAM,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,PCNXL2,KCNH3,MEF2D,SLC35D1,DSP,VPS53,MAT2A,FBXL5,SLC39A14,ZFAND3,ARHGAP21,KDM4B,ELP2,ASTN2,METTL6,NSMCE2,POLR3E,CAMKMT,RPS6KB1,METTL2B,CEP170,RAB30,BAG1,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,TRIM22,RNASEH2B,PSMF1,SNW1,TAF3,CFDP1,UNC13A,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,C15orf41,ACTR3B,SAMD4A,SPTAN1,TTPAL,VPS37A,DDX24,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,MRPL36,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,PHF5A,COPS4,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,PPARG,CDK4,ANK2,MARCKSL1,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,BSN,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,E2F4,DPP4,C3orf35,ADAM9,PRPF4,PPP3CC,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,PNPLA3,LRSAM1,SNX29,NIPSNAP1,IFT43,USP49,SETD2,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,SART1,OLFM2,SUCLG1,UPK3B,PAPD4,ARID2,NDUFAF2,NTSR1,SLC2A1,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PAG1,PPP1R9A,DDX60L,SEMA6A,URB1,ZNF121,FDX1,PLXNB1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,SOBP,TLCD1,KDM3B,AKAP8L,SSFA2,KIRREL2,RAB7A,ANKRD33B,CA5B,NHSL1,ZNF251,EIF3H,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,CPNE7,POLR1B,C12orf4,LRRIQ1,MON1A,SMARCAD1,PLAC8L1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,SMPDL3B,CDH24,NOL10,SAMD5,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,USP20,TMEM219,RBM26,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,CAMSAP2,EFHC1,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,TMEM206,PLCXD2,OSBPL1A,SPOP,GNAI1,GZF1,TRRAP,CCNT1,SH3RF1,LSM14A,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,CFD,HIC2,NRP1,WDR66,TNFRSF10D,BLMH,RFXAP,SPOCK2,SPOCK3,ZMAT3,NMD3,PRPF38B,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,DLGAP4,TATDN3,CENPB,DPM3,SSR4,PDCD5,NDUFS7,MTUS1,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,CNOT4,RTFDC1,FDFT1,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,ARID1A,TPRA1,EHBP1,SLC26A11,MTR,PHF6,ATP9B,SEC31A,CAT,ASCC3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,NOP56,DECR1,SLX4,ASNS,PPID,LPIN2,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,C1orf228,GON4L,PREX1,LRRC8A,GNL1,SATB2,MEGF11,MARCH6,SETD7,ERC1,SNCA,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,G6PD,LARGE,CBWD1,IFT140,SLC4A7,TRAF3,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,NEBL,SDCBP2,CELF1,DYNC2H1,ERRFI1,MS4A15,CLK2,NAV3,FER1L5,TMC7,SLC40A1,TTLL5,ZFYVE1,AGPAT4,TMEM126A,PACS1,BMS1,GUF1,KLF6,SLC23A2,RETSAT,DDX50,IREB2,ZNF155,ORC5,SVIL,ATM,APAF1,ADK,DDIT3,IPO4,IMMP2L,LETM1,LYRM4,ATRX,RARS2,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,CARM1,CEP128,SRPK2,DEAF1,DTNB,TNK2,SESN2,FBXW4,SKAP2,ITPA,TFPI,ARRDC3,VWCE,MINA,TMEM216,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,EME1,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,ZCCHC8,SCART1,STXBP6,UBXN1,SMG7,EVPL,QSER1,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,CCDC124,ZCCHC7,LRP3,AKAP11,MTHFD1,HSD17B14,ZNF629,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,APBB3,SYCP2L,BICD1,FSCN1,KIAA0355,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,TBL1X,FNBP1L,TBCK,PDE9A,N4BP2L2,TCF12,DMXL2,CHMP2A,FEZ2,SMARCA4,COBLL1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,AUP1,MAML3,NARS2,NPW,PRAME,ANTXR2,GRHL3,MRRF,ATXN1,EDEM2,DKC1,UBR4,BATF3,ARMC4,ALAD,DUS3L,KPNA3,HNRNPR,ARNTL,CEBPZ,WDR73,DUSP19,FKBP5,NFRKB,RNF130,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,IGF2BP2,ATF7IP,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,MFHAS1,FAM49A,GFM2,PEX7,SCN1B,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,SULT4A1,METTL23,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,CTIF,SERINC1,DAGLB,WDR35,AGTPBP1,VPS37B,POLR1C,ZSWIM6,GNB3,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,PCDH7,TOM1L1,C1orf159,NEK6,SREBF2,NSRP1,SYN2,RABGAP1L,RASSF3,FAAH2,C12orf76,PDS5B,WIZ,FNIP2,ZNF148,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,MCL1,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,STOML2,DDX3X,DLEU1,SUPT4H1,BRCA2,TMEM139,FIS1,RBP1,MEF2C,CARS,HERC2,EP400,CLDN15,KHDRBS1,SIRT7,NHS,RSF1,KCNJ14,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ZNF326,NOC3L,CALN1,PRMT5,MAP3K12,AGL,FMNL2,HMGCR,FADS1,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,PRDM16,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,ONECUT2,CPT1A,MBNL2,ABCF1,NCDN,ZNF655,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,DNM3,ZNF516,ABCA3,TRERF1,DDX18,BTBD2,NPAS2,ATP6V1A,PDK4,ACTR3,MYH9,AGAP6,TUBB6,SAFB2,STAM,EEA1,RPP30,PRKD3,BCAS2,ABCA12,ERI1,FMNL1,ATRIP,GSTA4,CEP63,MTHFD2L,MALL,FAM111B,STAMBP,NPM3,LGALS1,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,PES1,TAF2,GNG2,HLA-DMA,IQCH,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,LRCH1,TRIM36,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,PVRL3,ACAP3,SOX6,HNRNPM,DIS3L2,ULBP1,NUDC,C21orf58,FAM98A,DDHD1,FGF9,ERICH1,CLYBL,POLK,ARHGAP39,FRA10AC1,R3HDM2,ZNF467,UBE2K,PDE3B,CASC1,DDX49,FOXC1,KISS1R,RPA1,TRIB3,TOE1,RARS,ETFDH,BAZ2B,PXDN,NME1-NME2,PLPPR2,STX1A,ARID3B,SLC25A19,SLCO5A1,PTPN4,GPAM,PSAP,IGBP1,DOCK6,ANAPC4,KDM4C,CORO2B,PPARGC1B,TFIP11,POLR1A,MFGE8,HECTD3,CSNK2A1,RNF43,TMEM132A,TTI1,COX10,SEC16A,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,PPCDC,UBAP2L,ZNF85,ETV1,MPST,TMPO,PTPRK,SF3A1,CDC37,FLNC,METTL1,CHD9,SLC3A2,ZNF124,ABCC4,SKIV2L2,HARS,BAZ2A,KATNAL1,GDPD1,MED27,NOL6,GMFB,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,KIF16B,PEX1,GLS,MSRA,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,SARS,OXNAD1,AOC3,MCM6,STX8,LRRC28,HSD17B10,BARX2,ZFP36L1,RLF,DNAH1,RNF40,DOPEY1,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,BCS1L,WDR25,MEX3B,ZNFX1,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,PWP1,ATXN7,ITPRIPL1,SPAG9,FAM135A,SYNCRIP,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,HMBS,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,RBFOX2,LPCAT2,GPR143,RSL1D1,RNF24,LPCAT3,KDM1A,METTL16,CAD,UBR1,DNAJB6,ARMC5,FSIP2,IKBKB,ZDHHC6,HIRIP3,ANO8,RNF2,ETF1,ZFP37,HIBCH,CORO1A,AKNAD1,PRMT3,CASP10,CTC1,TMEM200A,SKIV2L,SEC24A,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,C1QTNF1,CPOX,MANBAL,SLC35F2,TMEM123,AKAP13,ENC1,ARL5B,NUP214,USP36,ATP5D,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,ZNF333,TIMM17A,ABHD3,ITGA2,ZNF436,TSSC1,PRRT3,NFASC,AP2S1,ZNF589,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,CWC27,PRICKLE2,HIST2H3D,GREB1,DDX31,FBXO31,CD44,PCK2,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,TPM4,DHX34,TEX14,PEAR1,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,ARMC3,ZRANB3,MKX,CENPP,TPD52L2,C20orf196,TMEM237,SRBD1,GPC2,ADAT2,SET,MSH3,GLG1,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,CGN,PRDX6,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,RAC3,AARS,UBR5,MGA,GIPR,RPS16,RNF111,VPS52,ME1,MEIS3,CEP135,PRADC1,FUT11,SEH1L,TBC1D8,DDN,DPF3,SLC38A6,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,SEMA3F,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,VPS13D,DNAH2,GREB1L,SEMA3C,TXN2,FAM118A,ZNF598,PTPN14,EFNB2,WDR75,DROSHA,EGR1,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,ANXA10,IGF2BP3,PRKCE,NAV1,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,SLC16A9,GTF3C3,SAMD13,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,AOC2,POLA1,KIAA0586,TTYH2,PTPN12,PLCB1,LYRM7,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,NSF,UBAP1,PMEPA1,ZZEF1,D2HGDH,RIOK3,PEX13,UMPS,MACROD1,MAP2K4,ZFHX2,RTTN,TBKBP1,PTCD2,AMOTL1,TRPM2,LIN28B,SPATA2L,RIBC2,URB2,HFM1,SPRYD7,C1QTNF7,OLA1,KLHL18,SPATS2L,AP1B1,TRIM66,PDE3A,TERF2IP,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SERPINH1,KMT2A,PLEKHA4,NAA35,ATP6AP1L,C18orf21,ZCCHC14,MPP6,RFC3,PDK1,MTIF2,SFXN4,WDPCP,KIAA1586,MED16,GALK2,PNN,POLG2,TBC1D16,STK10,DHX57,DCBLD2,VDR,HTR7,ZNF236,ALKBH1,MDN1,KLHDC4,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,SCAMP3,TTC27,CA11,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,MON2,IKBKAP,GDPD5,REEP5,FOXO3,MAD2L2,NEDD4,ZNF239,RGS17,COMMD9,PTRF,LRP2BP,NISCH,PMPCA,UPF2,RDX,COPS7B,NLGN3,NT5M,PLEKHG4,MBTPS2,PFKFB4,FAM120B,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,MMAA,ECH1,YIF1A,FBXO21,KLHL22,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,BRWD3,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,ZNF107,ANKRD18A,BCOR,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,EDC3,SMARCB1,RTN1,ZNF804A,RAP1A,LONRF2,THADA,YLPM1,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,SLC27A5,LONP1,TRIP13,PRKACB,TRIM14,TIMM50,LAMA4,ZBTB17,TRIM13,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,SERGEF,CHAF1A,CDHR3,PAF1,GEMIN5,TMEM132B,UBTF,EPN2,SUFU,GATA6,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,COPS6,ZNF397,DMTF1,TNRC6A,VIPR1,SLC12A7,CHST11,PIGN,FN1,SEC24D,TAF1,PAX2,DPF2,ALG8,MED13L,PHGDH,RHBDD1,ETFB,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,KRT20,RANBP6,TBXAS1,WWC1,PRDM1,C11orf65,ZSCAN16-AS1,ANKRD20A4,DNAH14,UBAP2,MYBBP1A,ATAD5,INTS5,SDCCAG8,HK2,EXOC4,KIAA1328,ZFP90,TMEM182,PDSS2,ZBTB24,ASH1L,PCNT,MMRN2,SLC5A5,CELSR3,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,ZSCAN5A,VPS18,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,MET,ZNF460,TSPAN14,TMEM14C,MOSPD1,TMLHE,HN1,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,PUSL1,RAB10,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,SLC25A11,SRFBP1,DISP1,HEATR1,SCARB1,USP11,TSPAN5,KLHL24,TNIK,SULT1C2,NSUN6,DBF4,CLSTN2,LETMD1,PPHLN1,CCDC7,PPP1R1C,MFSD10,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,IL17RE,GART,CTNNBL1,HAS3,TANK,DSG2,KDELC1,SHMT2,TTC17,AMOT,DMRT1,SLC25A1,TEAD1,PPP1R21,PSMC3IP,ANKMY2,MARS,PHACTR2,ARHGAP32,LENG8,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,PREPL,ZAK,MMP16,SLC16A10,CTXN1,HRH1 |
| 2.422e-16 | -35.96 | serous_carcinoma | COSMIC cancer mutations | serous_carcinoma | 11513 | 1646 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ZNF44,ABHD6,LPAR3,SKI,PDZD2,MMP7,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,CCDC57,HMBOX1,NRAS,LIMA1,UPP1,EHMT1,AP4B1,KIF15,C11orf80,C5AR1,WDHD1,ABCC2,MCM2,SLC9A5,ZNF197,AHNAK,RAD18,LRRC40,DIRAS1,RIOK1,RUNX1,ZNF532,P2RY11,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,CCDC88C,PABPC1,SAMD3,MYB,NOM1,RABEPK,LRRC20,GATAD2B,ZNF675,STAG1,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,ATAT1,MAP7D1,ST6GALNAC3,TRIM37,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,PDLIM1,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,GALE,SDSL,C16orf45,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,RPGRIP1L,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,GSTCD,DSP,VPS53,MAT2A,ZFAND3,FBXL5,ARHGAP21,KDM4B,ASTN2,NSMCE2,ARL13B,POLR3E,RPS6KB1,CEP170,CATSPERG,BAG1,MAPT,MORC2,COMMD10,SHQ1,XRRA1,ATG2B,GAS6,IP6K2,TRIM22,RNASEH2B,ZNF691,PSMF1,SNW1,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,SPTAN1,TTPAL,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,OXSR1,NSD1,SRCAP,HERC1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,COPS4,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DSC3,FMNL3,AEBP2,PPARG,CDK4,ANK2,HSPA5,SUMO3,MARCKSL1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,CXADR,BSN,DYRK1B,TCF7L1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,BEND6,USP15,FOXO1,CLK1,ITFG1,PRSS3,SMAD7,MAPK8IP3,FAN1,C1orf52,ARID1B,SPIRE1,SUB1,RNFT2,MLX,CEP290,NDRG4,CTR9,WNT16,LRSAM1,CWF19L2,SNX29,NIPSNAP1,USP49,SETD2,HAUS6,OBSCN,METTL22,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,CASS4,DTD1,GGT7,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,NTSR1,RPS29,SLC2A1,RIPK1,DENND3,TNKS1BP1,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,ZNF608,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,KIRREL2,VIM,NHSL1,ZNF251,TJAP1,EXO1,IFT81,ATG7,INTS9,MED20,EIF2B3,FAHD1,PARD3,ZNF507,DMGDH,MCM10,RFX1,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,TOP3A,FERMT2,ARHGEF12,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LPIN1,EXOC1,S100A10,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,OSBPL1A,SPOP,DOT1L,TRRAP,LSM14A,CCNT1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,DPM3,PRPF39,PDCD5,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,NOVA2,USPL1,LDOC1L,SCAF1,MYC,PIGG,MFAP2,EXOSC2,IFNGR2,RREB1,PCCA,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,DECR1,SLX4,ASNS,ARMC6,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,SETD7,ERC1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,SETD6,MID1,SSH2,BRAF,B4GALT5,FARS2,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,ABL1,NEBL,SDCBP2,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,GUF1,SLC23A2,RETSAT,DDX50,ZNF155,IREB2,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,PIGM,ZNF76,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,TIMM44,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CSMD3,ASB3,CLU,EME1,DCAF5,RHOBTB1,ZCCHC8,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ZNF354A,ISPD,PRF1,ZCCHC7,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,PDE9A,NR2C2AP,TCF12,DMXL2,CHMP2A,SNX27,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,TBCCD1,COBLL1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,MPHOSPH10,NVL,PPFIBP1,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,AUP1,MAML3,NARS2,ANTXR2,PRAME,GRHL3,METTL2A,POU2F1,MRRF,METTL15,UBR4,ARMC4,KPNA3,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,DUSP19,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,KLC4,PDE4B,WDR26,ATF7IP,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,FAM49A,MFHAS1,SCN1B,SEC24C,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,CTIF,DAGLB,GADD45A,SERINC1,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,WDR74,CSPP1,HLTF,NUP160,SYNJ1,AMBRA1,PABPC4,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,FAAH2,RABGAP1L,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,CNTNAP3B,CDK6,WLS,PTPRM,RFX2,AKAP12,PLEKHM3,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,HERC2,CARS,TNNC1,EP400,CLDN15,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,CLINT1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,SLC38A5,MCM5,ALKBH8,ZNF326,NOC3L,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,FMNL2,SERBP1,HMGCR,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,EVI5,ABCF1,ZNF655,VPS13C,LRP1B,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,MYH9,AGAP6,NECAP1,SAFB2,EEA1,STAM,HSPA1A,TMEM150C,PRKD3,ABCA12,ERI1,ZKSCAN1,PYCRL,ATRIP,GSTA4,CEP63,TMEM136,MTHFD2L,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,ARHGEF10,LGALS1,ADAM32,TTC28,FGFR1,PDE8B,TAF2,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,SERINC5,INSIG2,XPC,SESTD1,TRAK1,C1orf226,WDR37,JMJD6,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,KRI1,SUV39H2,GATC,ARHGAP1,LYPLA2,HNRNPM,SOX6,NUDC,DDHD1,FAM98A,C21orf58,FGF9,POLK,ARHGAP39,R3HDM2,FAM126B,IL6R,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,ARID3B,PLPPR2,SLCO5A1,PTPN4,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,UBAP2L,ZNF85,POLE3,ETV1,SF3A1,PTPRK,CDC37,TMPO,FLNC,CHD9,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,SKIV2L2,NOL6,ATG12,BRCA1,ZNF91,FLVCR1,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,NOMO3,SARS,AOC3,MCM6,STX8,LRRC28,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,TIMELESS,SYNJ2,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,ZNFX1,SUPT5H,NR2F1,VAC14,PGD,PWP1,ATXN7,SPAG9,FAM135A,ITPRIPL1,PALB2,SYNCRIP,SNAP23,DNAH17,PPP1R12B,ARHGAP12,HMBS,PRKAR2A,RNF114,KCTD7,RBFOX2,LPCAT2,GPR143,RSL1D1,PPP2R2A,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,DUS4L,FSIP2,DNAJB6,ARMC5,IKBKB,ETF1,ANO8,ZFP37,CORO1A,AKNAD1,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,GLTSCR2,THSD4,CPOX,C1QTNF1,AKAP13,ENC1,NUP214,ARL5B,TMEM186,USP36,BTBD11,RANBP2,RBBP8,SIX5,ZNF333,CLEC16A,ABHD3,ITGA2,PRRT3,ZNF18,NFASC,PUS1,ZNF589,PPIL3,ATXN7L2,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,C14orf159,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,FAM50A,NDUFV1,SACS,ZNF561,ANXA7,IFIT5,PRICKLE2,GREB1,DDX31,PCK2,ADAMTSL3,ZNF654,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,ARMC3,NEU1,MKX,CENPP,TPD52L2,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,UBR5,AARS,MGA,GIPR,VPS52,PAK1IP1,RNF111,ME1,PRADC1,CEP135,MEIS3,TBC1D8,DPF3,NR6A1,NOL8,EYA3,CUX1,TCEB3,SEMA3F,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,DNAH2,CCNB1IP1,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,CCDC53,OPHN1,GTF2IRD1,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,ZNF586,ENTPD5,ASAP1,ATIC,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,ADARB1,SCAF11,SIK3,SYNGAP1,AOC2,POLA1,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,NSF,ZZEF1,ZBTB12,RIOK3,UMPS,IQSEC2,MAP2K4,RTTN,PPDPF,PTCD2,AMOTL1,TRPM2,LIN28B,RWDD1,ZBTB37,URB2,RIBC2,HFM1,NDUFB5,OLA1,KLHL18,SPATS2L,AP1B1,SLC25A44,FOSL2,PDE3A,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,RFC4,PDK1,SFXN4,MTIF2,WDPCP,DLG4,PNN,GALK2,MED16,TBC1D16,STK10,DHX57,DCBLD2,VDR,HTR7,YIPF2,DNAJA3,ZNF236,ALKBH1,TRMT2A,ANXA2,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,ZNF280C,NFX1,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,NOL3,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,ZNF483,ZNF239,COMMD9,PTRF,LRP2BP,NISCH,PMPCA,UPF2,COPS7B,NLGN3,EXOSC4,LARP4B,PLEKHG4,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,ECH1,KLHL22,HELZ,HNRNPH3,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,NF1,KIF5A,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SLC29A1,BCOR,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,YLPM1,LONRF2,ATG3,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,SLC27A5,PRKACB,TRIP13,LONP1,TIMM50,LAMA4,ZBTB17,TRIM13,ZNF680,SLC38A1,GPCPD1,HDAC8,ZSCAN2,CDHR3,CHAF1A,UBTF,TMEM132B,GEMIN5,SUFU,GATA6,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,NRIP1,POLR1E,N4BP2,VOPP1,RANBP6,PDE4A,TBXAS1,WWC1,C11orf65,PRDM1,ANKRD20A4,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,ZFP90,TMEM182,PDSS2,C7orf26,ZBTB24,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,UBTD2,GBF1,ZSCAN5A,VPS18,FARSA,CAMTA2,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,HTRA2,MOSPD1,TMLHE,HN1,MCEE,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,TOR1AIP2,ATP8B2,C1orf174,RAB10,TPK1,RAD54B,WARS,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,DBF4,NSUN6,H2AFJ,CLSTN2,PPHLN1,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,KDELC1,SHMT2,CLDND1,TTC17,UTS2,AMOT,DMRT1,SLC25A1,PAQR6,MSX1,IL11RA,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,HSPA1B,ZNF708,MPP7,CUL2,ZRANB2,MBD6,PREPL,MMP16,ZAK,SLC16A10,CTXN1,HRH1 |
| 3.603e-16 | -35.56 | cytoplasm | cellular component | GO:0005737 | 10396 | 1495 | 17570 | 2233 |
PTP4A1,ARHGAP26,ADAM19,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,MKS1,TUBE1,SBF2,HMOX2,ABHD6,LPAR3,CIAPIN1,SKI,PDZD2,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,PPM1K,HMBOX1,EIF4E3,NRAS,LIMA1,UPP1,EXOC6B,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,MCM2,PYCR1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,BDH2,MPV17,RUNX1,TPM1,VASH2,SLC25A26,EPM2AIP1,TRIO,PIK3R4,PARN,CDC73,PITPNM1,CHN1,CNST,UBE3A,DHX37,APLF,TNPO3,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,MYB,RABEPK,ZNF675,IFRD1,ALG6,WDR61,STAG1,IDH3G,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,KPNA1,GSTO2,PDLIM1,RPL28,TRAP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,SGSM3,GALE,SDSL,RAB11FIP4,PAFAH1B1,SUGCT,VTI1A,GRINA,NUP43,ST3GAL6,LCLAT1,UBL5,RPGRIP1L,NDUFB3,SPG21,ACD,CLCN6,MMP14,PEG10,PXK,MGLL,DENND1A,LYST,LRRC75A-AS1,ZNF480,EIF3J,CCNDBP1,MEF2D,GSTCD,SLC35D1,DSP,NUDT15,VPS53,MAT2A,FBXL5,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,ASTN2,ARL13B,POLR3E,CAMKMT,RPS6KB1,CEP170,RAB30,BAG1,MAPT,MORC2,COMMD10,SHQ1,XRRA1,ATG2B,GAS6,TRIM22,PSMF1,TTLL11,POLR3D,UNC13A,ACOT11,ANXA5,PTGS1,FBXL19,ACTR3B,SAMD4A,PNMA1,RPL22L1,SPTAN1,VPS37A,ZC4H2,LDHA,NXN,CCDC113,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,SRCAP,HERC1,ACOX1,SRD5A3,BMP4,UQCC1,MTMR1,CYP24A1,CUL7,TRIM16,AAMDC,WDR13,SLC25A21,FAM13A,MAP2K3,AMPD3,COPS4,NCKIPSD,ANKRD11,METTL8,ZMYM2,SLC25A23,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,KRTCAP2,KCNH2,ODC1,DLST,LSG1,CXADR,MLLT10,BSN,LSS,HPRT1,INSIG1,CHD3,ARL4A,AHNAK2,DPP4,ADAM9,PPP3CC,TSEN2,MAGI1,UQCC2,USP15,CTU2,FOXO1,CLK1,NKD2,MAPK8IP3,FAN1,LAMTOR3,SMAD7,ZIC2,LYRM2,ARID1B,SPIRE1,MLX,CEP290,MBD2,NDRG4,VAPB,WNT16,PNPLA3,LRSAM1,NIPSNAP1,WARS2,IFT43,HAUS6,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,SNX24,CASS4,SIL1,DTD1,PTP4A2,SH3PXD2A,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,PAPD4,SLC48A1,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RPS29,RIPK1,SSBP2,TNKS1BP1,PPP1R9A,FDX1,ANKRD13A,IDI1,NUP133,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,ARHGAP17,AKAP8L,SSFA2,TEX19,RAB7A,VIM,CA5B,EIF3H,TJAP1,EXO1,ATG7,INTS9,HSPB8,EIF2B3,FAHD1,MUTYH,PARD3,DMGDH,NIFK,MINK1,KIZ,MCM10,HM13,AUH,AGO2,APRT,VARS,RBM19,POGZ,ANKRD54,SLC25A20,ADH5,TTC1,CPNE7,POLR1B,C12orf4,PCSK6,AP4S1,ABCF2,SLC35G1,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,DKK1,CACNB1,DSC2,TAF4,BCAS3,FNTB,USP20,RBPJ,XPO6,KIF1B,PRKCSH,GYG1,PRKCA,LPIN1,EXOC1,ZFYVE28,SUCLG2,DPH6,SPAG6,CSGALNACT2,ACADS,GDAP1,VSNL1,CAMSAP2,EFHC1,HIST1H2BL,ZDHHC14,DDX60,CLNS1A,OSBPL1A,GNAI1,GZF1,DDAH2,TRRAP,LSM14A,SH3RF1,HSPBAP1,ARL6IP5,CFD,XPNPEP1,NRP1,BLMH,BMI1,NMD3,C9orf78,CDC42EP2,JUP,LARS2,ST6GAL1,TATDN3,DPM3,CRACR2A,SSR4,PDCD5,NDUFS7,MTUS1,SLC7A11,MYC,PIGG,PLEKHA2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,RREB1,PCCA,RDH10,RAPGEF4,RAP1GAP2,RAP1B,NELFA,EHBP1,SLC26A11,MTR,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SRP68,MED15,BIVM,ZCCHC6,SQLE,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,PLEK2,HNRNPA3,RING1,FLNB,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,TTC3,RMDN3,CMPK1,ARL14EP,CASP8AP2,BRD4,PREX1,PCMT1,SATB2,MARCH6,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,CAMK2D,DCXR,G6PD,LARGE,FTSJ1,IFT140,TRAF3,TBXA2R,SETD6,XRCC4,MID1,VWA8,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,INPP1,PHLDA2,ABL1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,SLC40A1,PXN,TTLL5,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,GUF1,SLC23A2,INF2,RETSAT,IREB2,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,PIGM,LETM1,LYRM4,EIF3C,KMT2E,RARS2,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DEAF1,DTNB,TNK2,SESN2,SKAP2,SIRT6,ITPA,TFPI,ARRDC3,MINA,TMEM216,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,ST3GAL5,MPC1,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,CRCP,CLU,EME1,DCAF5,MTCH1,DCTN3,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,CCDC124,ZCCHC7,PRF1,ATP6V0D1,AKAP11,MTHFD1,HSD17B14,MSI2,HBG2,PPAT,ELOVL6,XPO5,ELP3,ZBED4,LIG4,EIF2A,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,APBB3,BICD1,FSCN1,FAT1,FDPS,SLC16A1,TMEM117,CDKAL1,PFDN2,FNBP1L,PDE9A,AGO3,DMXL2,TCF12,SNX27,CHMP2A,PSTPIP2,CEMIP,PIGH,PBX1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,KCTD11,SOCS1,NVL,CBR4,SNTG2,FHIT,ADCK4,VCL,C6orf89,AUP1,NARS2,ANTXR2,GRHL3,MRRF,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,ARMC4,ALAD,DUS3L,KPNA3,HNRNPR,ARNTL,WDR73,DUSP19,FKBP5,RNF130,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,CHCHD10,ATF7IP,IGF2BP2,WDR26,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,DCTN4,STC2,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,ARNTL2,PPP1R9B,DNMBP,KDM5B,GPHN,KDM5A,PSPC1,SULT4A1,METTL23,ASAP3,PDE2A,PEAK1,EIF5B,TMEM187,CTIF,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,TRAPPC12,NIT1,ASCC1,CSPP1,HLTF,CHAC1,NT5C3A,COA1,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,TOM1L1,SREBF2,NEK6,PMAIP1,SYN2,RASSF3,RABGAP1L,PDS5B,FNIP2,ZNF148,HRG,LYRM5,FXN,CDK6,PTPRM,WLS,MSRB3,AKAP12,MCL1,TMSB4X,SLC50A1,STOML2,DDX3X,BRCA2,FIS1,RBP1,LPP,MEF2C,CARS,TNNC1,HERC2,TRIP6,KHDRBS1,SLK,SIRT7,PRAF2,NHS,PLA2G12A,CLINT1,YARS2,ABCA7,SLC39A11,SH2B3,EIF2S2,ALKBH8,ANP32B,CALN1,PRMT5,MAP3K12,COQ3,AGL,FMNL2,TOMM34,SERBP1,EMC10,HMGCR,FADS1,PEA15,TIMM8B,BDNF,COL17A1,MYO10,RB1CC1,PRDM16,STPG1,EPS15L1,EIF4A2,RYR2,SMARCD3,IMPDH2,EVI5,MBNL2,CPT1A,ABCF1,ZNF655,NCDN,GTF2A1,CDK9,SURF1,GPN1,SENP3,CNOT6,COG5,SPRED2,FAM208B,DNM3,MAP2K5,ABCA3,BTBD2,ATP6V1A,NPAS2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,TMEM150C,PRKD3,ABCA12,ERI1,FMNL1,PYCRL,GSTA4,NT5C,CEP63,MTHFD2L,PERP,MALL,GARS,KRT7,STAMBP,ASUN,ATF7IP2,LGALS1,ARHGEF10,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,PES1,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,FUS,ANKS1A,TRIM36,NOL4L,SERINC5,INSIG2,XPC,TRAK1,ID2,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,GATC,TMSB10,ARHGAP1,LYPLA2,DIS3L2,ULBP1,NUDC,DDHD1,FGF9,CEP83,CLYBL,CEP295,ARHGAP39,MRPS10,UBE2K,PDE3B,FOXC1,TRIB3,TOE1,RARS,ETFDH,PXDN,STX1A,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,DOCK6,ANAPC4,CORO2B,SRM,BCAS4,PPARGC1B,TFIP11,POLR1A,HECTD3,NREP,CSNK2A1,RNF43,TMEM132A,TTI1,COX10,SEC16A,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,XRCC2,PPCDC,RAN,MPST,CDC37,TMPO,FLNC,METTL1,CHD9,GCNT2,SLC3A2,ABCC4,BAZ2A,HARS,KATNAL1,GDPD1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,MGST1,CCDC28B,KIF16B,PEX1,GLS,MSRA,ZNF622,TP53BP1,PER1,EEFSEC,CCDC146,TNFRSF1A,SGSM2,C2CD5,CHMP4C,XYLB,AOC3,OXNAD1,TTN,SARS,PGPEP1,STX8,MEX3A,HSD17B10,ZFP36L1,DNAH1,RNF40,ABCA5,PDE10A,PPIL2,SYNJ2,ALDH18A1,GMDS,NT5E,NAA38,TRAPPC9,CAMKK2,CRADD,PAXBP1,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,VAC14,PGD,PWP1,ATXN7,SPAG9,SYNCRIP,SNAP23,IRAK2,DNAH17,TBPL1,PPP1R12B,ARHGAP12,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,RBFOX2,LPCAT2,GPR143,PPP2R2A,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,DNAJB6,FSIP2,ARMC5,ZDHHC6,IKBKB,ETF1,HIBCH,CORO1A,AKNAD1,PRMT3,CASP10,SKIV2L,SEC24A,EVL,TUBA1A,DDX41,NARS,C1QTNF1,CPOX,AKAP13,ENC1,NUP214,TMEM186,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,SIX5,TIMM17A,CLEC16A,ZNF436,PUS1,SEPT5,AP2S1,PKIB,UNC13D,MIF4GD,MAP3K13,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,IQGAP2,PTPN2,SACS,NDUFV1,ANXA7,IFIT5,PRICKLE2,DDX31,CD44,PCK2,HSD17B12,TPM4,DHX34,TEX14,RAP1GDS1,GPNMB,RHOT2,PIK3CB,CHCHD6,TMEM175,NEU1,ARMC3,POLR3G,CENPP,TPD52L2,GPC2,SET,GLG1,EIF2S1,NDUFAF5,MYRF,RPS6KC1,GCSH,POLB,PRDX6,PRKAB2,DDX19A,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,GIPR,RPS16,RNF111,VPS52,ME1,CEP135,FUT11,SEH1L,DDN,SETD1B,ATG9A,ALDH1L2,NOL8,EYA3,CUX1,DESI1,HSH2D,FOXRED1,SH3GL1,SKIL,HSDL2,DNAH2,TXN2,SYNPO,PTPN14,IFT57,EGR1,ANKRD17,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ENTPD5,ASAP1,COPS3,ATIC,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,RABAC1,PLCB1,LYRM7,ARIH2,ZNF425,EPRS,KIDINS220,SERF2,NSF,PMEPA1,UBAP1,D2HGDH,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,PTCD2,AMOTL1,LIN28B,CCDC58,NDUFB5,OLA1,SPATS2L,SLC25A44,AP1B1,PDE3A,PAIP2,TERF2IP,FLAD1,TMEM184A,SHC1,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,PLEKHA4,NAA35,CFAP221,PDK1,MTIF2,SFXN4,WDPCP,DLG4,GALK2,POLG2,STK10,DHX57,CPED1,TAMM41,YIPF2,DNAJA3,ACP1,ALKBH1,ANXA2,MDN1,PDCD11,NOLC1,TROVE2,SCAMP3,C10orf2,TCF3,MRI1,NFX1,SLC25A12,RTN4,LIAS,CEP126,MON2,NOL3,IKBKAP,GDPD5,FOXO3,MAD2L2,TMCO6,NEDD4,DCTPP1,RGS17,COMMD9,PTRF,LRP2BP,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,COPS7B,RDX,UPF2,NLGN3,EXOSC4,YBX3,MAP3K14,LARP4B,NT5M,MBTPS2,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,APTX,PTK2,OASL,NOP58,MMAA,ECH1,YIF1A,KLHL22,COL26A1,ZDHHC11,STX18,MYOM2,PGAM5,RABEP1,LRRC41,STK4,SLC37A3,MVK,FEM1C,NF1,KIF5A,CERS5,FANCD2,RCHY1,PLOD1,BCOR,SIRT2,STK33,CUTC,AHCYL2,EDC3,MRPS30,SRPRB,RTN1,ANAPC1,RAP1A,YLPM1,ATG3,ANAPC10,RELB,HYAL1,IPP,JOSD1,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIM14,PRKACB,TIMM50,TRIM13,TXLNG,CMIP,GPCPD1,HDAC8,CAV1,SOX4,TCTN1,SERGEF,GEMIN5,RHOU,PAF1,UBE3D,EPN2,SUFU,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,BBIP1,GALNT10,COPS6,ZNF397,NOCT,DMTF1,TNRC6A,LDAH,PIGN,CHST11,AK2,FN1,SEC24D,PAX2,DPF2,GPAT3,ALG8,XPO7,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,CEP164,ATXN2,BANF1,GLTP,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,BLOC1S4,C19orf70,ISG15,DNAH14,MYBBP1A,SDCCAG8,HK2,EXOC4,RRAGA,PTRH2,PDSS2,ZNF706,ASH1L,PCNT,MYO7A,FAM210A,SLC9B2,CSTA,UBTD2,GBF1,SLC39A1,MIEF1,VPS18,FARSA,BRE,CCDC50,LYPLAL1,RPS6KL1,TMEM14C,HTRA2,TMLHE,MOSPD1,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,NLN,TOR1AIP2,ATP8B2,RAB10,WARS,TPK1,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,USP11,ECHDC1,KLHL24,TNIK,DNAJA4,SULT1C2,OXLD1,TKFC,CLSTN2,LETMD1,PPHLN1,PPP1R1C,MFSD10,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,IL17RE,GART,CTNNBL1,HAS3,TANK,KDELC1,SHMT2,TTC17,UTS2,AMOT,DMRT1,SLC25A1,MSX1,MARS,ARHGAP32,MEN1,SYMPK,NAPEPLD,TARS,HSPA1B,MFN2,ALG5,CUL2,NCBP2,PREPL,ZAK,MMP16,ARHGAP27,HRH1 |
| 4.822e-16 | -35.27 | NUCLEUS | MSigDB lists | NUCLEUS | 1396 | 282 | 17758 | 2279 |
PLRG1,HLTF,NUP160,UBR5,GABPB2,LPIN1,PDZD2,NEK6,ZFHX3,NSRP1,PDS5B,ZNF148,CDK6,NR6A1,RNMT,GNL3,NOL8,NFIA,WDHD1,MCM2,SAP30BP,SPOP,DDX3X,BRCA2,SUPT4H1,TRRAP,CCNT1,HIC2,BLMH,BMI1,EGR1,ZHX3,PRPF31,KHDRBS1,RSF1,PDCD7,PARN,DDX56,INTS7,MCM5,MYC,MED24,GTF3C3,GEMIN4,TERF2,NOM1,SCAF11,ZNF675,EXOSC2,RREB1,STAG1,POLA1,SMARCD3,ARID1A,SRA1,ARIH2,IRS1,KPNA1,HIF1A,CDK9,LEMD3,SRP68,PURB,WDR33,DHCR7,TRERF1,NPAS2,MYH9,FOSL2,HSPA1A,RING1,NOP56,TERF2IP,PHC2,RPP30,BCAS2,ACD,DTNBP1,INTS12,NT5C,MSH4,CMPK1,CDK12,CASP8AP2,SAP30,PMS1,STAMBP,MED16,CCNDBP1,TAF2,ELP2,SMARCC1,HIPK2,H2AFX,PAM,BRCC3,NOLC1,PDCD11,XRCC4,NCOR2,XRRA1,TRAK1,SF3A3,RTN4,JMJD6,RCAN1,TRIM22,IP6K2,IKBKAP,NOL3,RPS6KA5,FOXO3,MBNL1,TADA3,ABL1,SNW1,PTRF,TAF3,UPF2,PTGS1,PNMA1,HNRNPM,DDX24,APEX1,APTX,OASL,KLF6,NOP58,FOXC1,POLR2A,RPA1,TRIB3,RETSAT,HNRNPH3,ORC5,SVIL,ANAPC4,KAT6A,ATRX,NF1,UBN1,TFIP11,PPARGC1B,CSNK2A1,BCOR,GIT2,SNAPC4,SMARCB1,SRSF2,PHF5A,JAZF1,ANAPC11,ZNF85,POLE3,HCFC2,OGG1,CARM1,TRIP13,SRPK2,TMPO,SF3A1,TIMM50,DEAF1,ATF4,SIRT6,CDK4,TSN,MED27,NOL6,HDAC8,BRCA1,SERGEF,CHAF1A,BSN,UBTF,GEMIN5,DYRK1B,EIF4ENIF1,SUFU,TP53BP1,ARL4A,PQBP1,RAD51B,PRPF4,TTN,FOXO1,TAF1,SMG7,HES6,XPO7,ARID1B,SUB1,MLX,CEP290,VPS72,PPIL2,BUD31,GTF2H1,TIMELESS,NRIP1,POLR1E,CPSF3L,TRA2A,TLE3,ELP3,PSMA1,LIG4,SUPT5H,POP1,PWP1,ATXN7,MYBBP1A,SYNCRIP,INTS5,RRAGA,TESC,BCCIP,USP7,ASH1L,RBFOX2,SMARCA4,PBX1,RPAIN,BRE,MPHOSPH10,NVL,NUP133,DNAJB6,HIRIP3,CPSF3,HTRA2,MAML3,KAT8,AKAP8L,POU2F1,ATXN1,DKC1,ENC1,NUP214,BATF3,EXO1,RANBP2,RBBP8,IKZF4,KPNA3,HNRNPR,CEBPZ,ARNTL,INTS9,MUTYH,SMG1,MCM10,MAP1S,MED18,ATF7IP,ZNF346,FAM50A,DCTN4,SNAPC5,TOP1,PPP1R9B,KDM5B,KDM5A,TOP3A,RANGAP1,MEN1,PALLD,SYMPK,HSPA1B,POLR3G,GADD45A,ZNF330,TBX3,TAF4,SET,MSH3,NCBP2,ZRANB2,RBPJ,TAF12,NR2F2,POLR1C |
| 3.702e-15 | -33.23 | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN | 730 | 169 | 17758 | 2279 |
ZNF292,POLB,TRIM16,POLR1A,WDR13,CSNK2A1,MGA,TOM1L1,SRPRB,SRSF2,PHKA1,UBAP2L,IPP,FXN,ZNRD1,TRIP13,SEH1L,TMPO,METTL1,DBN1,HMBOX1,NRAS,ATF4,GDPD1,GMFB,TMEM216,AKAP12,PSMG1,MARCKSL1,MCM2,TIMM44,SPOP,MLLT10,RHOU,EPN2,SH3RF1,ARL6IP5,NSMCE1,PQBP1,RUNX1,FAM118A,RNF214,WDR75,STX8,SEC24D,ZCCHC8,PRPF31,KHDRBS1,OPHN1,NKD2,GTF2IRD1,PRPF39,TIMM10,CDC73,RHBDD1,SLC39A11,EIF2S2,TSPAN2,INTS7,MBD2,VPS72,MYC,TIMELESS,ALDH18A1,LPCAT1,COQ3,NT5E,USE1,EXOSC2,PPAT,EIF4A2,BCS1L,METTL22,CYB5B,TCF7L2,EXOC6,CAT,MYBBP1A,MTHFD2,SYNCRIP,SPEN,D2HGDH,ZBTB12,PTRH2,CDKAL1,CNOT6,HMBS,BPNT1,DDX10,BCCIP,PPDPF,OSBPL9,VTI1A,RIPK1,FOSL2,PELP1,NOP56,PRKD3,PUS3,MPHOSPH10,LYPLAL1,NUP133,WAC,ZDHHC6,IKBKB,SOCS6,DTNBP1,ZNF142,C16orf58,ETF1,HIBCH,SSBP1,TMLHE,PARP2,ARHGEF10,POU2F1,MRRF,GNL1,PNN,MED16,ENC1,ERC1,USP36,TMEM186,TPK1,ZFAND3,ELP2,KPNA3,HEATR1,MDN1,NOLC1,MUTYH,HMGA2,TCF3,ZNF280C,MYNN,FOXP1,MAD2L2,SFR1,DCTPP1,KRI1,GART,PSMG4,TMEM161A,DSG2,NISCH,DCTN4,POLR1B,CD44,SOX6,SPTAN1,APEX1,WDFY3,TMEM126A,TBRG4,FERMT2,KLF6,PEAK1,NOP58,TARS,POLR3A,SLC23A2,TRIB3,TOE1,ADAT2,MSH3,GPAM,ANAPC4,GCSH |
| 4.120e-15 | -33.12 | ovary-carcinoma-serous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-serous_carcinoma | 11219 | 1603 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ZNF44,ABHD6,LPAR3,SKI,PDZD2,MMP7,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,CCDC57,HMBOX1,NRAS,LIMA1,UPP1,EHMT1,AP4B1,KIF15,C11orf80,C5AR1,WDHD1,ABCC2,MCM2,SLC9A5,ZNF197,AHNAK,RAD18,LRRC40,DIRAS1,RIOK1,RUNX1,ZNF532,P2RY11,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,CCDC88C,PABPC1,SAMD3,MYB,NOM1,RABEPK,LRRC20,GATAD2B,ZNF675,STAG1,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,ATAT1,MAP7D1,ST6GALNAC3,TRIM37,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,PDLIM1,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,C16orf45,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,RPGRIP1L,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,C16orf58,INTS12,MSH4,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,GSTCD,DSP,VPS53,MAT2A,ZFAND3,FBXL5,ARHGAP21,KDM4B,ASTN2,NSMCE2,ARL13B,POLR3E,RPS6KB1,CEP170,CATSPERG,BAG1,MAPT,MORC2,COMMD10,SHQ1,XRRA1,ATG2B,GAS6,IP6K2,TRIM22,RNASEH2B,ZNF691,PSMF1,SNW1,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,SPTAN1,TTPAL,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,OXSR1,NSD1,SRCAP,HERC1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,COPS4,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DSC3,FMNL3,AEBP2,PPARG,CDK4,ANK2,HSPA5,SUMO3,MARCKSL1,LAMA2,KCNH2,ODC1,DLST,CXADR,BSN,DYRK1B,TCF7L1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,BEND6,USP15,FOXO1,CLK1,ITFG1,PRSS3,SMAD7,MAPK8IP3,C1orf52,ARID1B,SPIRE1,SUB1,RNFT2,MLX,CEP290,NDRG4,CTR9,WNT16,LRSAM1,SNX29,NIPSNAP1,USP49,SETD2,HAUS6,OBSCN,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,CASS4,DTD1,GGT7,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,RPS29,SLC2A1,RIPK1,DENND3,TNKS1BP1,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,PLXNB1,ZNF608,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,KIRREL2,VIM,NHSL1,ZNF251,TJAP1,EXO1,IFT81,ATG7,INTS9,MED20,EIF2B3,FAHD1,PARD3,ZNF507,DMGDH,MCM10,RFX1,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,TOP3A,FERMT2,ARHGEF12,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LPIN1,EXOC1,S100A10,ZFYVE28,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,SPOP,OSBPL1A,DOT1L,TRRAP,CCNT1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,DPM3,PRPF39,PDCD5,C1orf50,NDUFS7,MTUS1,TECTA,HR,NOVA2,USPL1,LDOC1L,SCAF1,MYC,PIGG,MFAP2,EXOSC2,IFNGR2,RREB1,PCCA,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,ALKBH3,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,DECR1,SLX4,ASNS,ARMC6,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,SETD7,ERC1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,SETD6,MID1,SSH2,BRAF,B4GALT5,FARS2,DNAJC22,OPA1,INPP1,GIGYF2,ABL1,NEBL,SDCBP2,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,GUF1,SLC23A2,RETSAT,DDX50,ZNF155,IREB2,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,PIGM,ZNF76,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CSMD3,ASB3,CLU,EME1,DCAF5,RHOBTB1,ZCCHC8,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,ZNF354A,ISPD,PRF1,ZCCHC7,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,PDE9A,NR2C2AP,TCF12,DMXL2,CHMP2A,SNX27,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,TBCCD1,COBLL1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,MPHOSPH10,NVL,PPFIBP1,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,AUP1,MAML3,NARS2,ANTXR2,PRAME,GRHL3,METTL2A,POU2F1,MRRF,METTL15,UBR4,ARMC4,KPNA3,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,DUSP19,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,KLC4,PDE4B,WDR26,ATF7IP,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,FAM49A,MFHAS1,SCN1B,SEC24C,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,KDM5A,SULT4A1,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,CTIF,DAGLB,GADD45A,SERINC1,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,WDR74,CSPP1,HLTF,NUP160,SYNJ1,AMBRA1,PABPC4,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,FAAH2,RABGAP1L,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,CNTNAP3B,CDK6,WLS,PTPRM,RFX2,AKAP12,PLEKHM3,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,HERC2,CARS,TNNC1,EP400,CLDN15,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,CLINT1,YARS2,ABCA7,SLC39A11,SH2B3,EIF2S2,SLC38A5,MCM5,ALKBH8,ZNF326,NOC3L,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,FMNL2,SERBP1,HMGCR,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,EVI5,ABCF1,ZNF655,VPS13C,LRP1B,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,MYH9,AGAP6,NECAP1,SAFB2,EEA1,STAM,HSPA1A,TMEM150C,PRKD3,ABCA12,ERI1,ZKSCAN1,PYCRL,ATRIP,GSTA4,CEP63,TMEM136,MTHFD2L,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,ARHGEF10,ADAM32,FGFR1,PDE8B,TAF2,IQCH,CDC16,HIPK2,WDR7,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,SERINC5,INSIG2,XPC,SESTD1,TRAK1,C1orf226,WDR37,JMJD6,BHLHE40,TGFB2,MBNL1,POM121,KRI1,SUV39H2,GATC,ARHGAP1,LYPLA2,HNRNPM,SOX6,NUDC,DDHD1,FAM98A,C21orf58,FGF9,POLK,ARHGAP39,R3HDM2,FAM126B,IL6R,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,ARID3B,PLPPR2,SLCO5A1,PTPN4,SLC25A19,PSAP,GPAM,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,UBAP2L,ZNF85,ETV1,SF3A1,PTPRK,CDC37,TMPO,FLNC,CHD9,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,SKIV2L2,NOL6,ATG12,BRCA1,ZNF91,FLVCR1,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,NOMO3,SARS,AOC3,MCM6,STX8,LRRC28,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,TIMELESS,SYNJ2,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,ZNFX1,SUPT5H,NR2F1,VAC14,PGD,ATXN7,SPAG9,FAM135A,ITPRIPL1,PALB2,SYNCRIP,SNAP23,DNAH17,PPP1R12B,ARHGAP12,HMBS,PRKAR2A,RNF114,KCTD7,LPCAT2,GPR143,RSL1D1,PPP2R2A,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,DUS4L,FSIP2,DNAJB6,ARMC5,IKBKB,ETF1,ANO8,ZFP37,CORO1A,AKNAD1,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,GLTSCR2,THSD4,CPOX,C1QTNF1,AKAP13,ENC1,NUP214,ARL5B,TMEM186,USP36,BTBD11,RANBP2,RBBP8,SIX5,ZNF333,CLEC16A,ITGA2,PRRT3,ZNF18,NFASC,PUS1,ZNF589,ATXN7L2,MIF4GD,MAP3K13,FAM46B,MAP1S,C14orf159,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,FAM50A,NDUFV1,SACS,ZNF561,ANXA7,PRICKLE2,GREB1,DDX31,PCK2,ADAMTSL3,ZNF654,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,ARMC3,NEU1,MKX,CENPP,TPD52L2,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRKAB2,TNFRSF21,TMEM109,ENAH,ADAMTS6,UBR5,AARS,MGA,GIPR,VPS52,PAK1IP1,RNF111,ME1,PRADC1,CEP135,MEIS3,TBC1D8,DPF3,NR6A1,NOL8,EYA3,CUX1,TCEB3,SEMA3F,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,DNAH2,CCNB1IP1,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,CCDC53,OPHN1,GTF2IRD1,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,ZNF586,ENTPD5,ASAP1,ATIC,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,ADARB1,SCAF11,SIK3,SYNGAP1,AOC2,POLA1,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,NSF,ZZEF1,ZBTB12,RIOK3,UMPS,IQSEC2,MAP2K4,RTTN,PPDPF,PTCD2,AMOTL1,TRPM2,LIN28B,RWDD1,ZBTB37,URB2,HFM1,NDUFB5,OLA1,KLHL18,SPATS2L,AP1B1,FOSL2,SLC25A44,PDE3A,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,KDM2A,UCHL5,GLYR1,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,NAA35,ZCCHC14,RFC4,PDK1,SFXN4,MTIF2,WDPCP,DLG4,GALK2,MED16,PNN,TBC1D16,STK10,DHX57,DCBLD2,VDR,HTR7,YIPF2,DNAJA3,ZNF236,ALKBH1,TRMT2A,ANXA2,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,ZNF280C,NFX1,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,NOL3,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,ZNF483,ZNF239,COMMD9,PTRF,LRP2BP,NISCH,PMPCA,UPF2,COPS7B,NLGN3,EXOSC4,LARP4B,PLEKHG4,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,ECH1,KLHL22,HELZ,HNRNPH3,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,NF1,KIF5A,FANCD2,TRPM6,PLOD1,RCHY1,ZNF107,SLC29A1,BCOR,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,YLPM1,LONRF2,ATG3,RELB,IPP,JOSD1,POLR3B,PCOLCE2,SLC27A5,PRKACB,TRIP13,LONP1,TIMM50,ZBTB17,LAMA4,TRIM13,ZNF680,SLC38A1,GPCPD1,HDAC8,ZSCAN2,CDHR3,CHAF1A,UBTF,GEMIN5,TMEM132B,GATA6,SUFU,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,CHST11,PIGN,FN1,TAF1,DPF2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,NRIP1,POLR1E,N4BP2,VOPP1,RANBP6,PDE4A,TBXAS1,WWC1,C11orf65,PRDM1,ANKRD20A4,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,ZFP90,TMEM182,PDSS2,C7orf26,ZBTB24,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,UBTD2,GBF1,ZSCAN5A,VPS18,FARSA,CAMTA2,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,HTRA2,MOSPD1,TMLHE,HN1,MCEE,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,TOR1AIP2,ATP8B2,C1orf174,RAB10,TPK1,RAD54B,WARS,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,DBF4,NSUN6,H2AFJ,CLSTN2,PPHLN1,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,KDELC1,SHMT2,CLDND1,TTC17,UTS2,AMOT,DMRT1,SLC25A1,PAQR6,MSX1,IL11RA,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,HSPA1B,ZNF708,MPP7,CUL2,ZRANB2,MBD6,PREPL,MMP16,ZAK,SLC16A10,CTXN1,HRH1 |
| 1.522e-14 | -31.82 | ncRNA metabolic process | biological process | GO:0034660 | 449 | 118 | 16441 | 2138 |
SART1,LIN28B,RARS2,AARS2,LAGE3,POP5,NUP43,NUP160,SNAPC4,AARS,SBDS,NOP56,RPP30,METTL16,CHD7,FARSA,RPS16,PUS3,MPHOSPH10,DUS4L,ERI1,NUP133,TRMU,INTS12,RAN,TRMT10A,YARS,TRMT12,UTP4,FTSJ3,SEH1L,NARS2,METTL1,WDR36,GARS,NARS,SKIV2L2,HARS,NPM3,NOL8,METTL2A,NOL6,METTL15,DKC1,NUP214,CLNS1A,PUSL1,WARS,PES1,SMAD3,GEMIN5,RANBP2,DUS3L,TRMT5,INTS9,FTSJ1,SRFBP1,PUS1,HEATR1,TSEN2,ZC3H8,PDCD11,NOLC1,METTL2B,CARS,CTU2,NIFK,SARS,DROSHA,UTP14A,LARS2,SIRT7,AGO2,HSD17B10,FARS2,VARS,YARS2,POM121,MRPS11,ELL,DDX56,GATC,INTS7,TRMT13,ALKBH8,HARS2,ICE2,GTF3C3,EXOSC4,GEMIN4,POLR1B,ERI3,PRMT5,FBL,POLR1E,PPA1,CPSF3L,DIS3L2,EXOSC2,WARS2,ELP3,TYW1,WBSCR22,UTP15,MARS,NOP58,POLR2A,TARS,POP1,RARS,EPRS,ZBTB8OS,INTS5,ADAT2,CDKAL1,DTD1,NCBP2,AGO3 |
| 2.843e-14 | -31.19 | cellular nitrogen compound biosynthetic process | biological process | GO:0044271 | 3389 | 576 | 16441 | 2138 |
GGT1,ASCC1,AARS2,MRPL10,HLTF,CCNL2,ZNF44,NUP160,PABPC4,SKI,ZNF37A,MMP7,SREBF2,ZFHX3,IKZF5,ATP5G2,ZNF148,KDM5C,ZNRD1,FXN,HMBOX1,EIF4E3,RNMT,UPP1,NFIA,RFX2,C5AR1,ZNF197,STOML2,DDX3X,ZNF266,SUPT4H1,RAD18,BDH2,RUNX1,ZNF532,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,YARS2,EIF2S2,ZNF326,MED24,MRPL21,PRMT5,ZNF518B,PABPC1,PPA1,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,SMARCD3,ST6GALNAC3,IMPDH2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,NME7,RPL28,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,ST3GAL6,SAFB2,ZKSCAN1,WAC,MTHFD2L,LSM10,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,MAT2A,FGFR1,TAF2,KDM4B,ELP2,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,ID2,JMJD6,TRIM22,BHLHE40,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,RPL22L1,SOX6,POLK,MRPS10,ZNF467,FOXC1,UBC,MRPL36,RPA1,TRIB3,NSD1,SRCAP,RARS,BAZ2B,POLE2,ARID3B,KDM4C,SRM,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,COX10,BIRC2,AMPD3,SRSF2,PHF5A,HKR1,PPCDC,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,CHD9,ZNF124,ATF4,AEBP2,PPARG,HARS,BAZ2A,ZNF414,MED27,BRCA1,ODC1,ZNF91,MLLT10,GLS,HPRT1,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,DLX2,BEND6,SARS,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,GMDS,NT5E,WARS2,PAXBP1,TLE3,SETD2,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,TBPL1,ZNF430,HMBS,GGT7,MPI,ID1,SUCLG1,ARID2,RPS29,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,DENR,CAD,NRF1,ZBTB21,NUP133,ETF1,ZFP37,RNF2,KAT8,KDM3B,PCGF3,NARS,CPOX,NUP214,ZNF251,EIF3H,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ATG7,ZNF436,MED20,ZNF18,EIF2B3,ZNF507,NIFK,RFX1,AGO2,APRT,VARS,FOXP1,ZNF594,ZNF561,SELT,POLR1B,SNAPC5,TRNP1,FOXN3,ZNF654,ZMYM5,POLR3A,POLR3G,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,GABPB2,AARS,MGA,LPIN1,RPS16,RNF111,CHD2,ME1,MEIS3,SEH1L,ZNF646,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,DENND4A,SAP30BP,GZF1,SKIL,DDAH2,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,LARS2,ZHX3,GTF2IRD1,SSR4,CHD5,IGF2BP3,HR,ZNF586,SCAF1,ATIC,MYC,GTF3C3,PRPS1,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,ZNF425,ASCC3,EPRS,MTHFD2,HIF1A,SRP68,SPEN,ZBTB12,MED15,PURB,UMPS,NCOR1,CNDP2,ZFHX2,ZNF254,ZBTB37,UROD,FOSL2,RING1,TERF2IP,FLAD1,CHD7,ZNF827,ASNS,KDM2A,UCHL5,LPIN2,MRPS27,CMPK1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,ZBTB25,BAZ1A,VDR,MSX2,DNTTIP1,SMARCC1,G6PD,ZNF236,MBTD1,FTSJ1,TROVE2,NCOR2,C10orf2,TCF3,ZNF280C,NFX1,FARS2,MYNN,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,HARS2,YBX3,FAM120B,TSHZ1,TTLL5,APEX1,PSAT1,ADSL,KLF6,GUF1,MMAA,POLR2A,ZFP62,ZNF155,ADK,DDIT3,KAT6A,ZNF76,PHF3,EIF3C,KMT2E,ATRX,RARS2,CERS5,RCHY1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,MRPS30,SRPRB,YLPM1,JAZF1,ZEB1,RELB,POLR3B,YARS,CARM1,TRIP13,ELOF1,ZBTB17,DEAF1,SESN2,ZNF195,TXLNG,ZNF680,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,ST3GAL5,TAF9B,UBTF,PAF1,GATA6,CC2D1B,MKL2,PQBP1,CRCP,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,AK2,TAF1,PAX2,DPF2,MED13L,DDIT4,NAMPT,ELL,ZNF354A,NRIP1,POLR1E,ZNF629,MTHFD1,VOPP1,ZNF234,TSTA3,PPAT,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,LIG4,PRDM1,EIF2A,ISG15,MYBBP1A,RRAGA,CDKAL1,ZFP90,TBL1X,NR2C2AP,ZBTB24,TCF12,ASH1L,PBX1,SMARCA4,ZSCAN5A,FARSA,RRN3,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,TMLHE,MAML3,NARS2,PRAME,TFCP2,SFSWAP,GRHL3,MRRF,POU2F1,ATXN1,WARS,BATF3,TPK1,IKZF4,ALAD,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,PPHLN1,CHCHD10,ATF7IP,MED18,GFM2,MRPS11,GART,DMRT1,PKNOX1,RPS6KB2,ARNTL2,MSX1,KDM5B,ZNF821,TEAD1,KDM5A,PSPC1,ZNF324B,SCMH1,MARS,MEN1,ZNF407,EIF5B,TARS,ZNF221,RERE,ZNF708,NCBP2,POLR1C,NFKBIB |
| 3.238e-14 | -31.06 | MANALO_HYPOXIA_DN | MSigDB lists | MANALO_HYPOXIA_DN | 272 | 82 | 17758 | 2279 |
SRM,LETM1,ID1,DDX18,WDR74,URB2,DDX19A,NAT10,POP5,NUP43,NUP160,NLE1,CUTC,DHX35,URB1,MAP2K3,NOP56,CAD,RPP30,SRSF2,ARMC6,NVL,UCHL5,PAK1IP1,FXN,YARS,TRIP13,SEH1L,NARS2,RFC3,PARP2,PSMG1,BRCA1,DKC1,MCM2,RBM28,ODC1,CHAF1A,MLLT10,EXO1,H2AFX,HEATR1,PUS1,TSEN2,EIF2B3,NOLC1,METTL2B,MCM10,MCM6,C17orf80,UTP14A,DBF4,VARS,GART,SACS,NOP16,MCM5,ATIC,PRMT5,PRPS1,SNAPC5,MTHFD1,EXOSC2,GINS3,PPAT,ELOVL6,PSMC3IP,ABCF2,WBSCR22,TOP3A,BCS1L,MFN2,POLR3G,TSR1,TOE1,POLE2,EIF2S1,UMPS,HMBS,DHCR7,IPO4,GCSH |
| 5.119e-14 | -30.60 | acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | acute_myeloid_leukaemia_therapy_related | 1584 | 303 | 17775 | 2278 |
ARHGAP26,MYCBP2,ADAM19,PLRG1,ENAH,IKBIP,UBR5,AMBRA1,PCDH7,ZFHX3,MAD1L1,RNF111,SRRM2,CCDC57,NRAS,OSBP2,NR6A1,LIMA1,PTPRM,VSNL1,CUX1,SEMA3F,PLCXD2,GREB1L,RUNX1,ZMAT3,EP400,TMEM63C,DROSHA,CELSR1,NHS,OPHN1,PID1,SLC1A1,SLC39A11,IGF2BP3,CHN1,TECTA,RBM20,NAV1,SLC7A11,USPL1,ASAP1,MED24,LPCAT1,CAV2,FMNL2,GATAD2B,BDNF,KCNQ3,PRIM2,RB1CC1,PRDM16,RAPGEF4,ZNF512B,RYR2,ST6GALNAC3,PLCB1,EHBP1,ARIH2,PHF6,ATP9B,LRP1B,TASP1,KIDINS220,TRAP1,NSF,CNDP2,PDLIM5,ARHGAP10,MAP2K4,ZFHX2,COG5,RAB11FIP4,DNM3,TRERF1,C16orf95,NPAS2,DDR2,VTI1A,CD99L2,TMEM104,SPATS2L,PTPRG,PABPC1L,PDE3A,ZNF827,CD96,ASNS,SPG21,ABCA12,TBC1D22A,WAC,MRPS27,DTNBP1,C16orf58,TTC3,MGLL,DENND1A,LYST,WDPCP,PREX1,PCNXL2,SATB2,MEGF11,TTC28,ERC1,HTR7,CAMK2D,IQCH,CDC16,ELP2,KDM4B,ASTN2,CAMKMT,WDR7,LARGE,KLHDC4,MDN1,ANKS1A,LAMA5,CEP170,TRIM36,COMMD10,SHQ1,BRAF,TTC27,TRAK1,ATG2B,OPA1,REEP5,POM121,ABL1,NEBL,C15orf41,SOX6,DIS3L2,DDHD1,FAM98A,FGF9,TTLL5,CLYBL,ARHGAP39,NXN,BMS1,RSBN1,PPIP5K2,UBE2K,CCDC150,HERC1,STX18,ATM,PTPN4,SVIL,APAF1,SORCS2,DOCK6,CORO2B,IMMP2L,LYRM4,NF1,PPARGC1B,SLC25A21,BCOR,FAM13A,COX10,RTN1,THADA,ZNHIT6,JAZF1,ZEB1,POLR3B,TRIP13,CEP128,DSC3,LAMA4,TXLNG,CMIP,KATNAL1,ANK2,GPCPD1,KSR2,LAMA2,DLST,BSN,TMEM132B,MSRA,GATA6,HLCS,DNAJC1,EEFSEC,CCDC146,MKL2,RAD51B,PQBP1,DPP4,CSMD3,PRPF4,GALNT10,ZC3H8,TNRC6A,XYLB,CHST11,FOXO1,STX8,BARX2,QSER1,ELL,SEMA3D,SNX29,VOPP1,TRAPPC9,LAMC1,ELOVL6,PRDM1,AGAP1,CYB5B,SYT1,VAC14,GRIK4,UBAP2,BICD1,FAT1,HK2,EXOC4,SIL1,CDKAL1,TMEM117,DDX10,TBCK,NAPA,PAPD4,OLFM2,ARID2,NDUFAF2,SLC2A1,PPP1R9A,DHX35,ANKRD13A,BRE,CCDC50,NVL,DNAJB6,SLC38A2,MYH15,ETF1,FHIT,AHCYL1,COL5A2,FAM172A,KIRREL2,PARP2,THSD4,AKAP13,RAB10,WARS,TPK1,SMAD3,CLEC16A,TSSC1,SCARB1,RNF130,EIF2B3,ZNF589,SMG1,PARD3,TMCC1,DNAJA4,SULT1C2,PDE4B,CLSTN2,ATF7IP,SEMA3E,SOGA1,FOXP1,BMP6,MAN1A1,PTPN2,CTNNBL1,DCTN4,STC2,LDLRAD3,AMOT,ADAMTSL3,CRIM1,SULT4A1,DHX34,ARHGEF12,PHACTR2,PALLD,PDE2A,ZNF407,NAALADL2,CHCHD6,CDH24,C20orf196,DAGLB,L3MBTL3,VPS37B,BCAS3,RPS6KC1,MIPOL1,ZAK |
| 5.119e-14 | -30.60 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | 1584 | 303 | 17775 | 2278 |
ARHGAP26,MYCBP2,ADAM19,PLRG1,ENAH,IKBIP,UBR5,AMBRA1,PCDH7,ZFHX3,MAD1L1,RNF111,SRRM2,CCDC57,NRAS,OSBP2,NR6A1,LIMA1,PTPRM,VSNL1,CUX1,SEMA3F,PLCXD2,GREB1L,RUNX1,ZMAT3,EP400,TMEM63C,DROSHA,CELSR1,NHS,OPHN1,PID1,SLC1A1,SLC39A11,IGF2BP3,CHN1,TECTA,RBM20,NAV1,SLC7A11,USPL1,ASAP1,MED24,LPCAT1,CAV2,FMNL2,GATAD2B,BDNF,KCNQ3,PRIM2,RB1CC1,PRDM16,RAPGEF4,ZNF512B,RYR2,ST6GALNAC3,PLCB1,EHBP1,ARIH2,PHF6,ATP9B,LRP1B,TASP1,KIDINS220,TRAP1,NSF,CNDP2,PDLIM5,ARHGAP10,MAP2K4,ZFHX2,COG5,RAB11FIP4,DNM3,TRERF1,C16orf95,NPAS2,DDR2,VTI1A,CD99L2,TMEM104,SPATS2L,PTPRG,PABPC1L,PDE3A,ZNF827,CD96,ASNS,SPG21,ABCA12,TBC1D22A,WAC,MRPS27,DTNBP1,C16orf58,TTC3,MGLL,DENND1A,LYST,WDPCP,PREX1,PCNXL2,SATB2,MEGF11,TTC28,ERC1,HTR7,CAMK2D,IQCH,CDC16,ELP2,KDM4B,ASTN2,CAMKMT,WDR7,LARGE,KLHDC4,MDN1,ANKS1A,LAMA5,CEP170,TRIM36,COMMD10,SHQ1,BRAF,TTC27,TRAK1,ATG2B,OPA1,REEP5,POM121,ABL1,NEBL,C15orf41,SOX6,DIS3L2,DDHD1,FAM98A,FGF9,TTLL5,CLYBL,ARHGAP39,NXN,BMS1,RSBN1,PPIP5K2,UBE2K,CCDC150,HERC1,STX18,ATM,PTPN4,SVIL,APAF1,SORCS2,DOCK6,CORO2B,IMMP2L,LYRM4,NF1,PPARGC1B,SLC25A21,BCOR,FAM13A,COX10,RTN1,THADA,ZNHIT6,JAZF1,ZEB1,POLR3B,TRIP13,CEP128,DSC3,LAMA4,TXLNG,CMIP,KATNAL1,ANK2,GPCPD1,KSR2,LAMA2,DLST,BSN,TMEM132B,MSRA,GATA6,HLCS,DNAJC1,EEFSEC,CCDC146,MKL2,RAD51B,PQBP1,DPP4,CSMD3,PRPF4,GALNT10,ZC3H8,TNRC6A,XYLB,CHST11,FOXO1,STX8,BARX2,QSER1,ELL,SEMA3D,SNX29,VOPP1,TRAPPC9,LAMC1,ELOVL6,PRDM1,AGAP1,CYB5B,SYT1,VAC14,GRIK4,UBAP2,BICD1,FAT1,HK2,EXOC4,SIL1,CDKAL1,TMEM117,DDX10,TBCK,NAPA,PAPD4,OLFM2,ARID2,NDUFAF2,SLC2A1,PPP1R9A,DHX35,ANKRD13A,BRE,CCDC50,NVL,DNAJB6,SLC38A2,MYH15,ETF1,FHIT,AHCYL1,COL5A2,FAM172A,KIRREL2,PARP2,THSD4,AKAP13,RAB10,WARS,TPK1,SMAD3,CLEC16A,TSSC1,SCARB1,RNF130,EIF2B3,ZNF589,SMG1,PARD3,TMCC1,DNAJA4,SULT1C2,PDE4B,CLSTN2,ATF7IP,SEMA3E,SOGA1,FOXP1,BMP6,MAN1A1,PTPN2,CTNNBL1,DCTN4,STC2,LDLRAD3,AMOT,ADAMTSL3,CRIM1,SULT4A1,DHX34,ARHGEF12,PHACTR2,PALLD,PDE2A,ZNF407,NAALADL2,CHCHD6,CDH24,C20orf196,DAGLB,L3MBTL3,VPS37B,BCAS3,RPS6KC1,MIPOL1,ZAK |
| 8.312e-14 | -30.12 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | 778 | 173 | 17758 | 2279 |
PTP4A1,CUL7,PHF3,FEM1C,TRIM16,GPBP1L1,CSNK2A1,CHAC1,FAM13A,SLC6A8,AARS,DST,ABL2,AMPD3,PDZD2,IKZF5,PMAIP1,CNIH3,RELB,CSGALNACT2,HMBOX1,TRIM13,SLC3A2,NRAS,ATF4,BAZ2A,PPARG,RNMT,UPP1,TFPI,CUX1,GMFB,GNAI1,SKIL,LSS,TCF7L1,DDAH2,PER1,HSPBAP1,AHNAK2,HIC2,CLU,DMTF1,SLC12A7,CLK1,SEC24D,KHDRBS1,SLK,SIRT7,DLGAP4,LAMTOR3,MED13L,GTF2IRD1,RSF1,RLF,MTUS1,DDIT4,ANXA10,NAMPT,ELL,ZNF354A,SLC7A11,USPL1,PDE10A,GTF2H1,CNOT4,SIK3,RB1CC1,SETD2,HAUS6,JMJD1C,CPT1A,MBNL2,TCF7L2,HERPUD1,MTHFD2,SPAG9,UBAP1,KIAA0355,SNAP23,RIOK3,ARHGAP12,N4BP2L2,ZNF254,PAFAH1B1,PPP2R2A,RSL1D1,ST3GAL6,FOSL2,STAM,ZSCAN5A,NRF1,SOCS1,KDM2A,CAMTA2,DNAJB6,SETD5,WAC,SLC38A2,CLCN6,SERPINH1,LYST,SEC24A,ZCCHC14,BRD4,PTBP2,GON4L,AKAP8L,RAB7A,SFSWAP,POU2F1,MEF2D,MARCH6,SERP1,STK10,FGFR1,USP36,RAD54B,TJAP1,PLIN2,ZC3H12A,SLC39A14,KDM4B,LMBR1L,ZNF557,KLF4,ABHD3,ITGA2,SLC4A7,TRIM36,TMCC1,KLHL24,MAP1S,JMJD6,RCAN1,ATF7IP,IP6K2,BHLHE40,RPS6KA5,MFHAS1,RGS17,DCTN4,STC2,TANK,PTGS1,UPF2,CELF1,TTC17,MAP3K14,PKNOX1,KDM6B,MSX1,KDM5B,FGF2,WDFY3,ZMYM5,DHX34,IL6R,OASL,PALLD,KLF6,NEU1,TRIB3,BAZ2B,SERINC1,GADD45A,ARID3B,STX1A,VPS37B,RPS6KC1,RABEP1,DDIT3,HRH1 |
| 8.414e-14 | -30.11 | organelle organization | biological process | GO:0006996 | 3164 | 541 | 16441 | 2138 |
ARHGAP26,ACTG1,AARS2,MRPL10,MKS1,TUBE1,HLTF,COA1,NUP160,AMBRA1,NEK6,PMAIP1,AP1M1,MAD1L1,PDS5B,KDM5C,FXN,LIMA1,EHMT1,KIF15,WDHD1,MCL1,MCM2,TMSB4X,STOML2,DDX3X,RBSN,BRCA2,SUPT4H1,MPV17,FIS1,TPM1,BANP,EP400,SIRT7,PIK3R4,RSF1,CDC73,YARS2,MCM5,WDR60,MED24,ANP32B,MRPL21,PRMT5,MAP3K12,TOMM34,FMNL2,MYB,GATAD2B,TIMM8B,WDR61,STAG1,TSPYL4,RB1CC1,PRDM16,ARID5B,ATAT1,SMARCD3,MAP7D1,SNAP25,TRIM37,ONECUT2,DYNC1H1,TSR1,NME7,EHMT2,FGFBP1,LEMD3,KIAA0196,ARHGAP10,PAFAH1B1,ATP6V1A,ACTR3,VTI1A,MYH9,NUP43,EEA1,RPGRIP1L,ACD,FMNL1,WAC,MSH4,CEP63,LYST,KMT2D,ASUN,ARHGEF10,ATP6V0A1,DSP,TTC28,PES1,ARHGAP21,CDC16,KDM4B,ELP2,MISP,NSMCE2,HIPK2,ARL13B,BRCC3,YEATS2,LAMA5,RAB30,MAPT,HMGA2,XPC,JMJD6,ATG2B,POM121,TADA3,GATC,SUV39H2,TMSB10,UNC13A,ANXA5,ACTR3B,DIS3L2,NUDC,DDHD1,CEP83,MRPS10,CCDC113,UBC,MRPL36,ANXA1,RPA1,SRCAP,NSD1,POLE2,ACOX1,UQCC1,ANAPC4,CORO2B,KDM4C,CUL7,TRIM16,PPARGC1B,COX10,SEC16A,BIRC2,ABL2,COPS4,NCKIPSD,XRCC2,RAN,POLE3,CDC37,DBN1,CHD9,FMNL3,AEBP2,HARS,BAZ2A,CDK4,KATNAL1,COL4A3BP,ATG12,BRCA1,CXADR,CCDC28B,PEX1,TCF7L1,CHD3,E2F4,PER1,RAD51B,UQCC2,USP15,CHMP4C,TTN,MCM6,STX8,NKD2,ZIC2,RLF,DNAH1,ARID1B,SPIRE1,RNF40,CEP290,MBD2,VPS72,VAPB,CTR9,TIMELESS,LRSAM1,TRAPPC9,IFT43,USP49,SETD2,HAUS6,BCS1L,OBSCN,TRAPPC6B,SUPT5H,TCF7L2,NAP1L5,ATXN7,PALB2,SNAP23,TBPL1,BRSK2,NAPA,USP7,ARID2,GPR143,PPP2R2A,TNKS1BP1,PPP1R9A,SEMA6A,KDM1A,DENR,NRF1,NUP133,DNAJB6,IKBKB,CCDC40,HIRIP3,RNF2,CORO1A,PRMT3,CTC1,SEC24A,KAT8,KDM3B,EVL,TUBA1A,RAB7A,VIM,NUP214,TJAP1,RANBP2,IFT81,RBBP8,TIMM17A,ATG7,AP2S1,PARD3,ESCO1,MINK1,KIZ,MAP1S,ARFIP2,CSNK1A1,POGZ,HIST2H2AB,IQGAP2,HIST2H3D,POLR1B,SMARCAD1,TOP3A,TEX14,HIST1H4J,PALLD,RHOT2,CHCHD6,ZRANB3,CENPP,TMEM237,L3MBTL3,SET,MSH3,BCAS3,EIF2S1,NDUFAF5,TAF12,CGN,CUL4A,PRKAB2,ENAH,PRKCA,RAC3,LPIN1,EXOC1,S100A10,CHD2,CEP135,SEH1L,GDAP1,DPF3,SETD1B,ATG9A,EYA3,CAMSAP2,HIST1H2BL,SUPT20H,FOXRED1,SON,DOT1L,TRRAP,LSM14A,CCNB1IP1,BMI1,WDR75,IFT57,JUP,CDC42EP2,OPHN1,PID1,CCDC47,CHD5,NDUFS7,NAV1,ASAP1,USPL1,MYC,COPS3,CAV2,TERF2,USE1,DDX28,PRIM2,ANAPC13,POLA1,KIAA0586,ARID1A,SEC31A,ASCC3,NSF,PEX13,NCOR1,IQSEC2,SMYD3,RTTN,PTCD2,SYT17,BIRC6,HFM1,PLEK2,CORO6,FLNB,RING1,BLOC1S2,TERF2IP,NUBPL,CHD7,SLX4,KDM2A,SHC1,PPID,DTNBP1,MRPS27,SSBP1,KMT2A,SAP30,RFC4,BRD4,RFC3,PDK1,MTIF2,WDPCP,PREX1,DLG4,SATB2,SETD7,POLG2,SNCA,BAZ1A,SMARCC1,DNAJA3,MBTD1,H2AFX,IFT140,MDN1,ANXA2,SETD6,NOLC1,MID1,NCOR2,SSH2,C10orf2,TCF3,KIF5C,RTN4,CEP126,MLH1,MON2,OPA1,NOL3,IKBKAP,RPS6KA5,MAD2L2,ABL1,NEBL,ELP5,NISCH,PMPCA,COPS7B,HARS2,DYNC2H1,TTLL5,PXN,APEX1,BMS1,PTK2,KLHL22,INF2,STX18,ATM,SVIL,NDUFS5,BRWD3,IPO4,KAT6A,IMMP2L,LETM1,KMT2E,NF1,ATRX,UBN1,RARS2,FANCD2,SIRT2,BCOR,EDC3,SMARCB1,MRPS30,DST,ANAPC1,KANSL1,CNIH3,ATG3,ANAPC11,ANAPC10,MYH3,LONP1,CARM1,TRIP13,TIMM50,SRPK2,SESN2,ITPA,SIRT6,TMEM216,HDAC8,CAV1,KMT2C,TCTN1,TIMM44,CHAF1A,ARPC3,UBTF,RHOU,PAF1,HLCS,BBIP1,CLU,COPS6,NOCT,EMSY,DCTN3,TAF1,SEC24D,VTA1,TIMM10,TOX4,CEP164,ATXN2,BANF1,ATP6V0D1,KRT20,ELP3,JMJD1C,WBSCR22,LIG4,EIF2A,SYT1,BLOC1S4,C19orf70,UBE2E1,EXOC6,BICD1,FSCN1,FAT1,SDCCAG8,EXOC4,HK2,SLC16A1,TBL1X,FNBP1L,CHMP2A,ASH1L,PCNT,CELSR3,PSTPIP2,TNXB,MYO7A,TBCCD1,COBLL1,SMARCA4,PIBF1,GBF1,SBDS,MIEF1,VPS18,RRN3,BRE,HTRA2,PHLDB2,MRRF,TOR1AIP2,DKC1,ATP8B2,RAB10,RAD54B,ARMC4,COPS5,ARC,BRD9,TMEM33,TNIK,DNAJC2,SUPT6H,DYM,H2AFJ,CHCHD10,ATF7IP,GFM2,SFI1,MRPS11,PEX7,SEC24C,FBL,TTC17,AMOT,MICAL3,TOP1,KDM6B,PPP1R9B,KDM5B,KDM5A,SCMH1,MEN1,PDE2A,RERE,MFN2,GADD45A,WDR35,AGTPBP1,ZAK |
| 8.978e-14 | -30.04 | MOV10 (Mov10 RISC complex RNA helicase) | protein interactions | 4343 | 985 | 223 | 16036 | 2270 |
SRM,ZNF76,MVK,TRIM16,DPH1,TFIP11,TNFRSF21,POLR1A,TMEM132A,PRKCA,AARS,SCAF8,GIT2,PCYOX1L,ANAPC1,COPS4,MARVELD2,EMC8,POLR3B,POLE3,YARS,AVEN,SF3A1,CDC37,DBN1,ATF4,TXLNG,OSBP2,HARS,ITPA,LIMA1,WLS,NOL8,HSPA5,NOL6,DESI1,MSRB3,SUMO3,SEMA3F,CAV1,PITPNB,C10orf76,FOXRED1,SAP30BP,LSG1,GEMIN5,SUPT4H1,TP53BP1,CHD3,LUC7L3,E2F4,MPV17,CRCP,XPNPEP1,GREB1L,GALNT10,MAGI1,TXN2,SYNPO,EMSY,SEPHS2,PIGN,TRIP6,TAF1,SIRT7,DLGAP4,PIK3R4,LAMTOR3,XPO7,IGF2BP3,FAM192A,CEP164,USPL1,ATXN2,IGF2BP1,ALDH18A1,AGL,TOMM34,EMC10,NIPSNAP1,TRAPPC9,PAXBP1,PRIM2,ANAPC13,SIGMAR1,POLA1,AOC2,TRA2A,EPS15L1,XPO5,RAP1B,OBSCN,WWC1,ZNFX1,ARID1A,SUPT5H,CYB5B,CPT1A,MTR,PGD,DAGLA,POP1,CAT,SEC31A,APBB3,ASCC3,PALB2,EHMT2,SRRD,UBAP1,KIAA0754,FDPS,RIOK3,SURF1,SENP3,UMPS,CNDP2,TCF12,PTCD2,AMOTL1,UROD,TBCCD1,TUBB6,SAFB2,PUDP,SLC39A1,NOP56,FLAD1,SPG21,TMEM184A,SHC1,NVL,PPFIBP1,ZDHHC6,MRPS27,CLCN6,RNF2,CMPK1,AHCYL1,ZNF460,LSM10,UTP4,ZC3H3,PRPF19,KDM3B,PRAME,PMS1,DDX41,AKAP8L,FAM111B,SFXN4,SNHG1,MEF2D,DKC1,TBC1D16,UBR4,STK10,HSD3B7,S100A16,PUM3,PES1,CDC16,SMARCC1,ELP2,COPS5,TRMT2A,KLHDC4,USP11,NOLC1,ZBTB11,TMEM141,YDJC,PDE4B,TKFC,PPHLN1,NFX1,ARFIP2,LETMD1,JMJD6,WDR37,POGZ,MAD2L2,TTLL11,COMMD9,NPRL2,FAM50A,ANXA7,ZNF561,SEC24C,UNC13A,HARS2,FIRRE,S100A14,FBL,PKNOX1,HNRNPM,NUDC,RPS6KB2,PXN,DDX24,WDFY3,ABCF2,ZC3H18,WDR18,TBRG4,MRPS10,RAP1GDS1,PDE2A,C8orf33,POLR2A,UBC,RPA1,ANXA1,ETFDH,INF2,CDH24,TPD52L2,COQ9,HNRNPH3,CUL2,SLC25A19,KDM4C,IPO4 |
| 9.061e-14 | -30.03 | chromosome organization | biological process | GO:0051276 | 966 | 206 | 16441 | 2138 |
CUL4A,TRIM16,UBN1,KMT2E,ATRX,FANCD2,BCOR,HLTF,SIRT2,PRKCA,SMARCB1,COPS4,KANSL1,PDS5B,CHD2,KDM5C,POLE3,TRIP13,SEH1L,CARM1,DPF3,CHD9,AEBP2,SETD1B,SIRT6,ITPA,BAZ2A,CDK4,EHMT1,EYA3,WDHD1,HDAC8,SUPT20H,HIST1H2BL,BRCA1,KMT2C,MCM2,CHAF1A,DOT1L,DDX3X,PAF1,UBTF,TCF7L1,BRCA2,TRRAP,SUPT4H1,HLCS,CHD3,PER1,CCNB1IP1,COPS6,BMI1,EMSY,USP15,CHMP4C,BANP,WDR75,EP400,TTN,MCM6,TAF1,SIRT7,RSF1,RLF,CDC73,CHD5,ARID1B,TOX4,RNF40,MCM5,COPS3,MBD2,MYC,VPS72,MED24,CTR9,ANP32B,PRMT5,MAP3K12,TERF2,MYB,GATAD2B,WDR61,PRIM2,USP49,TSPYL4,PRDM16,POLA1,JMJD1C,ELP3,ARID5B,SETD2,WBSCR22,LIG4,SMARCD3,ARID1A,SUPT5H,TRIM37,UBE2E1,TCF7L2,NAP1L5,ASCC3,ATXN7,PALB2,EHMT2,TBL1X,NCOR1,SMYD3,USP7,CHMP2A,ASH1L,ARID2,SMARCA4,TNKS1BP1,PIBF1,RING1,KDM1A,TERF2IP,CHD7,SLX4,BRE,KDM2A,ACD,NUP133,WAC,HIRIP3,RNF2,MSH4,KMT2A,PRMT3,CTC1,SAP30,KAT8,KDM3B,RFC4,KMT2D,BRD4,RFC3,SATB2,SETD7,DKC1,RAD54B,BAZ1A,SMARCC1,KDM4B,ELP2,COPS5,NSMCE2,MBTD1,H2AFX,BRCC3,BRD9,SETD6,YEATS2,HMGA2,DNAJC2,NCOR2,ESCO1,SUPT6H,XPC,C10orf2,TCF3,H2AFJ,JMJD6,ATF7IP,MLH1,IKBKAP,RPS6KA5,POGZ,HIST2H2AB,TADA3,SUV39H2,ELP5,HIST2H3D,COPS7B,FBL,DIS3L2,TOP1,KDM6B,APEX1,KDM5B,SMARCAD1,KDM5A,TOP3A,TEX14,SCMH1,HIST1H4J,MEN1,UBC,ZRANB3,ANXA1,RERE,RPA1,CENPP,NSD1,SRCAP,KLHL22,POLE2,L3MBTL3,SET,MSH3,ATM,TAF12,IPO4,KDM4C,KAT6A |
| 1.009e-13 | -29.93 | brainstem | COSMIC cancer mutations | brainstem | 3233 | 545 | 17775 | 2278 |
ARHGAP26,ADAM19,CACNA1H,ABHD6,LPAR3,SKI,PDZD2,ZFHX3,SYN2,RABGAP1L,MAD1L1,KDM5C,FXN,AVEN,FTSJ3,CNTNAP3B,NRAS,PTPRM,EHMT1,KIF15,AKAP12,ABCC2,PLEKHM3,C10orf76,STOML2,DLEU1,DDX3X,AHNAK,BRCA2,RAD18,RUNX1,ZNF532,CARS,HERC2,EP400,TRIO,NHS,CDC73,RBM20,CNST,KIAA1671,APLF,ZNF326,GEMIN4,COQ3,MAP3K12,PABPC1,FMNL2,ZNF675,STAG1,KCNQ3,RB1CC1,PRDM16,EPS15L1,RYR2,ST6GALNAC3,SNAP25,EVI5,MBNL2,VPS13C,LRP1B,NME7,TRAP1,PDLIM5,ARHGAP10,SGSM3,COG5,DNM3,ZNF516,TRERF1,BTBD2,VTI1A,CD99L2,ST3GAL6,SAFB2,EEA1,CD96,ABCA12,ERI1,TBC1D22A,SETD5,CLCN6,CEP63,MGLL,ZC3H3,KIAA1549,DENND1A,LYST,FAM111B,FAM171A2,PCNXL2,MEF2D,TTC28,DSP,VPS53,FGFR1,PDE8B,ZFAND3,FBXL5,ARHGAP21,IQCH,CDC16,KDM4B,ASTN2,NSMCE2,HIPK2,CAMKMT,WDR7,ANKS1A,METTL2B,LRCH1,MORC2,HMGA2,WDR37,TGFB2,RSRC1,MBNL1,TAF3,CFDP1,UNC13A,C15orf41,SOX6,DIS3L2,CLYBL,NXN,CCDC113,DDX49,PXDN,SLCO5A1,PTPN4,MTMR1,DOCK6,CORO2B,BCAS4,RBM33,TFIP11,PPARGC1B,SLC25A21,FAM13A,COX10,GIT2,SCAF8,ARHGAP18,PHKA1,ANKRD11,PTPRK,VPS13B,TMPO,FAM184A,FLNC,ABCC4,PPARG,ANK2,MED27,GDPD1,NOL6,LAMA2,BRCA1,FLVCR1,CRYBG3,KIF16B,TCF7L1,MSRA,CHD3,EEFSEC,CCDC146,DPP4,DLX2,MAGI1,CHMP4C,XYLB,ITFG1,PRSS3,MEX3A,DNAH1,DOPEY1,RNF40,ABCA5,SAMD11,PPIL2,VAPB,CCDC167,SYNJ2,GMDS,PNPLA3,SNX29,TRAPPC9,CRADD,HAUS6,UTP15,WDR25,OBSCN,TCF7L2,PRPF40B,GRIK4,SYNCRIP,CASS4,DDX10,SH3PXD2A,USP7,SART1,OLFM2,ARID2,NDUFAF2,GPR143,ZNF608,NRF1,NUP133,ARMC5,ZDHHC6,ANO8,MYH15,CTC1,PRPF19,KDM3B,PCGF3,AKAP8L,THSD4,ANKRD33B,VIM,AKAP13,ENC1,NUP214,BTBD11,LMBR1L,CLEC16A,ABHD3,ATG7,TSSC1,PRRT3,PARD3,ZNF507,ATXN7L2,AUH,MAP3K13,FAM46B,ARFIP2,RBM19,RMI1,IQGAP2,PTPN2,SACS,CWC27,PRICKLE2,GREB1,SELT,HSD17B12,ADAMTSL3,LRRIQ1,FERMT2,ARHGEF12,PALLD,CHCHD6,PIK3CB,POLR3A,MKX,POLR3G,CENPP,SAMD5,NOL10,SRBD1,L3MBTL3,TAF4,TBX3,BCAS3,RPS6KC1,KIF1B,CGN,PRDX6,ADAMTS6,PRKCA,UBR5,MGA,CHD2,ALDH1L2,C2orf76,GNG7,CUX1,ZDHHC14,SON,DDX60,OSBPL1A,GNAI1,TRRAP,SH3RF1,VPS13D,SEMA3C,WDR66,NRP1,BLMH,SPOCK3,PTPN14,EFNB2,WDR75,C9orf78,CELSR1,DROSHA,CCDC53,LARS2,ANKRD17,OPHN1,PID1,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,ASAP1,SCAF1,SAMD13,LPCAT1,EXOSC2,SIK3,PRIM2,SYNGAP1,POLA1,RAPGEF4,PLCB1,MTR,ATP9B,ASCC3,ALKBH3,ZZEF1,SPEN,VCAN,D2HGDH,MED15,ZCCHC6,PURB,PEX13,MACROD1,MAP2K4,RTTN,SYT17,UROD,OLA1,SPATS2L,PLEK2,PTPRG,PDE3A,CHD7,ZNF827,DECR1,TMEM184A,KDM2A,DTNBP1,MRPS27,NBEA,TTC3,CMPK1,ATP6AP1L,RFC4,WDPCP,PREX1,SATB2,MED16,STK10,ERC1,DHX57,HSD3B7,BAZ1A,HTR7,CAMK2D,ZNF236,LARGE,SLC4A7,ANXA2,MDN1,PDCD11,MID1,BRAF,SCAMP3,TTC27,TCF3,ZNF280C,NFX1,FARS2,RCAN1,MLH1,MON2,OPA1,FAM8A1,ZNF483,RGS17,COPS7B,CLK2,TSHZ1,FER1L5,TMC7,TTLL5,WDFY3,TMEM126B,TBRG4,GUF1,SLC23A2,IREB2,HELZ,STX18,SVIL,ATM,MYOM2,ADK,BRWD3,IMMP2L,LYRM4,NF1,ATRX,ANKRD18A,BCOR,STK33,AHCYL2,ZNF804A,RTN1,THADA,JAZF1,GPATCH1,POLR3B,B3GNTL1,CEP128,GPM6A,FBXW4,ZNF195,CMIP,KSR2,MTHFD1L,COTL1,ZSCAN2,SGK2,SERGEF,CHAF1A,YTHDF2,TAF9B,GEMIN5,TMEM132B,CCDC3,DNAJC1,CC2D1B,FAM114A2,MKL2,CSMD3,ABCC3,GALNT10,DMTF1,MTCH1,TNRC6A,SLC12A7,FN1,STXBP6,SMG7,EVPL,RHBDD1,SIPA1L3,ATXN2,MTHFD1,ZNF629,VOPP1,KRT20,TSTA3,PPAT,XPO5,C11orf65,CORIN,ANKRD20A4,AGAP1,SYT1,DNAH14,HERPUD1,KIAA0355,FAT1,SDCCAG8,EXOC4,SLC16A1,CDKAL1,TMEM117,KIAA1328,TCF12,DMXL2,CHMP2A,PCNT,SLC5A5,COBLL1,SMARCA4,ST7L,ARSJ,GBF1,DHX35,RIOK2,BRE,SNTG2,FHIT,ADCK4,ITGAX,MET,MAML3,MCEE,ACSL5,COL5A2,FAM172A,PARP2,NLN,EDEM2,DKC1,UBR4,TPK1,ARMC4,IKZF4,ZNF557,SRFBP1,RNF130,SMG1,TMCC1,TNIK,SULT1C2,DYM,ARL15,NSUN6,CLSTN2,ATF7IP,SEMA3E,PPP1R1C,ENOX1,BMP6,PRKCH,IL17RE,SEC24C,ERI3,FBL,DMRT1,MICAL3,MARCH9,CRIM1,ANKMY2,ARHGAP32,PDE2A,ZNF407,NAALADL2,CTIF,RERE,ZNF708,MPP7,AGTPBP1,ANKRD30BL,PREPL,MMP16,ARHGAP27 |
| 1.198e-13 | -29.75 | DAZARD_RESPONSE_TO_UV_NHEK_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_DN | 303 | 87 | 17758 | 2279 |
PHF3,ID1,NPAS2,ATRX,PAFAH1B1,KIAA0232,RCHY1,SSBP2,SLC25A44,ZNF44,UBR5,BIRC2,PHC2,DST,MPHOSPH10,RABGAP1L,ZNF148,KIAA0922,TBC1D8,VPS13B,ZCCHC14,CHD9,PMS1,TRIM13,SKAP2,MTIF2,WDHD1,MARCH6,SPOP,SMAD3,BAZ1A,SLC7A1,INSIG1,ADNP,LSM14A,DMTF1,CEP170,LPP,TMCC1,EFNB2,HMGA2,INSIG2,FOXO1,PIK3R4,SMAD7,MED13L,WDR37,TGFBR2,FOXO3,POGZ,DDIT4,IGF2BP3,MTUS1,ABL1,SH2B3,DOPEY1,SACS,MBD2,MYC,NRIP1,LPCAT1,CNOT4,NAV3,SCAF11,WDFY3,KDM5A,ARID5B,ZBED4,WWC1,FERMT2,RSBN1,PTK2,PPIP5K2,DKK1,IRS1,BAZ2B,HELZ,POLE2,SPEN,FAT1,RBPJ,NR2F2,FNBP1L,SGSM3,N4BP2L2,ZBTB24,KAT6A |
| 1.483e-13 | -29.54 | macromolecular complex | cellular component | GO:0032991 | 4883 | 768 | 17570 | 2233 |
ASCC1,THOC5,ACTG1,DCP1B,MRPL10,NAT10,MKS1,CACNA1H,TUBE1,CSPP1,CCNL2,NUP160,ABHD6,SYNJ1,PABPC4,NOS1AP,SKI,NEK6,SREBF2,ZFHX3,NSRP1,ATP5G2,RASSF3,AP1M1,EMC8,MAD1L1,PDS5B,SRRM2,ZNRD1,FTSJ3,CDK6,EIF4E3,KLHL23,RNMT,EXOC6B,AP4B1,KIF15,MCL1,DCUN1D5,MCM2,RBM28,STOML2,DDX3X,BRCA2,SUPT4H1,RAD18,FIS1,FIP1L1,MEF2C,TNNC1,EP400,TRIP6,KHDRBS1,SIRT7,PIK3R4,RSF1,PDCD7,KCNJ14,CDC73,ABCA7,CNST,UBE3A,EIF2S2,INTS7,MCM5,CACNB2,ZNF326,MED24,GEMIN4,MRPL21,PRMT5,AGL,PABPC1,EMC10,KLRD1,PEA15,GATAD2B,GTF2H3,TIMM8B,COL17A1,WDR61,STAG1,KCNQ3,MYO10,RB1CC1,PRDM16,EPS15L1,EIF4A2,RYR2,ATAT1,SMARCD3,SNAP25,TRIM37,SRA1,ABCF1,IRS1,DYNC1H1,LRP1B,GTF2A1,PDLIM1,RPL28,EHMT2,CDK9,SENP3,CNOT6,KIAA0196,WDR33,SRP14,COG5,DNM3,GTF2H2C,PAFAH1B1,ATP6V1A,NPAS2,BTBD2,ACTR3,VTI1A,MYH9,NECAP1,TUBB6,NUP43,ZMAT2,EEA1,MCM9,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,ACD,ERI1,WAC,INTS12,MSH4,PXK,ZC3H3,LSM10,PMS1,KMT2D,KRT7,EIF3J,ATP6V0A1,DSP,VPS53,MAT2A,FGFR1,PES1,TAF2,GNG2,FBXL5,HLA-DMA,CDC16,ELP2,NSMCE2,HIPK2,POLR3E,FUS,BRCC3,YEATS2,LAMA5,CATSPERG,CEP170,MAPT,HMGA2,INSIG2,XPC,SESTD1,SF3A3,ID2,AKT1S1,RNASEH2B,PSMF1,MBNL1,TTLL11,TADA3,SNW1,NPRL2,POLR3D,GATC,SUV39H2,TAF3,CFDP1,FBXL19,ACTR3B,RPL22L1,HNRNPM,DIS3L2,NUDC,FAM98A,FBXO17,CEP83,VPS37A,MRPS10,CCDC113,IL6R,PDE3B,FOXC1,ANXA1,MRPL36,RPA1,RARS,SRCAP,POLE2,STX1A,IGBP1,ANAPC4,KDM4C,CUL7,BCAS4,PPARGC1B,TFIP11,POLR1A,CSNK2A1,TTI1,COX10,BIRC2,SCAF8,HNRNPLL,SRSF2,PHF5A,COPS4,PHKA1,NCKIPSD,XRCC2,UBAP2L,RAN,POLE3,TMPO,SF3A1,CDC37,METTL1,RBCK1,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,KATNAL1,HSPA5,MED27,NOL6,ATG12,SUMO3,BRCA1,KRTCAP2,KCNH2,DLST,CXADR,KIF16B,ZNF622,TCF7L1,INSIG1,TP53BP1,CHD3,EEFSEC,E2F4,TNFRSF1A,RAD51B,PRPF4,TSEN2,CTU2,TTN,MCM6,STX8,MEX3A,LAMTOR3,SMAD7,HES6,BARX2,DNAH1,ARID1B,RNF40,SUB1,CEP290,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,NAA38,LAMC1,IFT43,HAUS6,BCS1L,UTP15,RNH1,MEX3B,SUPT5H,VAC14,TCF7L2,PRPF40B,GRIK4,ATXN7,SYNCRIP,SNAP23,DNAH17,TBPL1,NAPA,SH3PXD2A,PRKAR2A,BCCIP,SART1,NDUFA5,CYLD,OLFM2,PAPD4,SUCLG1,ARID2,RPS29,PPP2R2A,RIPK1,TNKS1BP1,RADIL,PELP1,PLXNB1,KDM1A,CAD,NUP133,GRIN2C,UBR1,IKBKB,MYH15,RNF2,ETF1,CORO1A,PRMT3,CASP10,CTC1,PRPF19,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,TUBA1A,DDX41,RAB7A,C1QTNF1,VIM,ENC1,EIF3H,ATP5D,SMAD3,RANBP2,IFT81,RBBP8,TIMM17A,KLF4,ITGA2,INTS9,PUS1,MED20,EIF2B3,AP2S1,PPIL3,PARD3,ESCO1,MCM10,HM13,MAP3K13,AGO2,MAP1S,CSNK1A1,POGZ,HIST2H2AB,IQGAP2,NDUFV1,CWC27,HIST2H3D,POLR1B,FBXO31,CD44,TRNP1,SMARCAD1,ABCF2,TPM4,TEX14,FERMT2,RANGAP1,HIST1H4J,EXOG,PALLD,PIK3CB,CHCHD6,POLR3A,POLR3G,CACNB1,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,EIF2S1,FNTB,RBPJ,TAF12,ITGB4,KIF1B,GCSH,CGN,POLB,CUL4A,PRKAB2,PLRG1,RAC3,MGA,EXOC1,RPS16,RNF111,VPS52,SEH1L,SPAG6,DPF3,SNU13,SETD1B,NR6A1,EYA3,GNG7,TCEB3,CAMSAP2,SUPT20H,HIST1H2BL,FOXRED1,CLNS1A,SH3GL1,SPOP,GNAI1,SKIL,TRRAP,CCNT1,LSM14A,NSMCE1,LUC7L3,DNAH2,NRP1,BMI1,PRPF38B,WDR75,IFT57,DROSHA,JUP,ANKRD17,CCDC53,PRPF31,DPM3,PRPF39,SSR4,TGFBR2,CHD5,NDUFS7,MTUS1,NAV1,HR,COPS3,MYC,GTF3C3,IGF2BP1,PLEKHA2,CNOT4,PRPS1,CAV2,TERF2,EXOSC2,DDX28,PRIM2,ANAPC13,POLA1,TTYH2,PTPN12,ARID1A,NELFA,PLCB1,ARIH2,PHF6,SEC31A,EPRS,KIDINS220,HIF1A,UBAP1,SRP68,SPEN,MED15,PURB,NCOR1,CPT1C,VMA21,AMOTL1,NDUFB5,C1QTNF7,KLHL18,SPATS2L,POP5,AP1B1,HNRNPA3,RING1,BLOC1S2,NOP56,TERF2IP,PHC2,SLX4,SHC1,KDM2A,UCHL5,DTNBP1,MRPS27,RMDN3,KMT2A,NAA35,CDK12,ATP6AP1L,SAP30,RFC4,BRD4,RFC3,PDK1,DLG4,LRRC8A,SATB2,MED16,PNN,MARCH6,SERP1,ERC1,SNCA,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,DNAJA3,H2AFX,IFT140,TRAF3,ANXA2,PDCD11,XRCC4,TROVE2,MID1,NCOR2,UTP14A,TCF3,KIF5C,MLH1,IKBKAP,MAD2L2,NEDD4,SFR1,PTRF,ELP5,TRIAP1,COPS7B,UPF2,CELF1,EXOSC4,DYNC2H1,YBX3,LARP4B,PXN,TTLL5,APEX1,WDFY3,KCNMA1,APTX,NOP58,POLR2A,FBXO21,KLHL22,COL26A1,HNRNPH3,STX18,ORC5,ATM,SVIL,MYOM2,NDUFS5,APAF1,IPO4,DDIT3,STK4,KAT6A,IMMP2L,EIF3C,ATRX,KMT2E,PTPRA,KIF5A,RCHY1,PPIL1,BCOR,SIRT2,SNAPC4,EDC3,SMARCB1,MRPS30,DST,SRPRB,ANAPC1,RAP1A,CNIH3,KANSL1,JAZF1,ATG3,ZNHIT6,ANAPC11,ANAPC10,MYH3,RELB,IPP,ZEB1,GPATCH1,POLR3B,NDUFA6,SLC27A5,OGG1,CARM1,PRKACB,TIMM50,TNK2,DEAF1,FBXW4,SIRT6,MINA,TMEM216,HDAC8,CAV1,SOX4,KMT2C,TCTN1,ARPC3,CHAF1A,TAF9B,YTHDF2,GEMIN5,RHOU,PAF1,EPN2,EIF4ENIF1,GATA6,HLCS,RLTPR,PQBP1,CRCP,BBIP1,CLU,EME1,ZC3H8,COPS6,NOCT,DCAF5,TNRC6A,DCTN3,VIPR1,FN1,ZCCHC8,TAF1,SEC24D,STXBP6,PAX2,DPF2,UBXN1,MED13L,TIMM10,TOX4,CEP164,ELL,P3H1,ATXN2,BUD31,NRIP1,ATP6V0D1,AKAP11,POLR1E,CPSF3L,MSI2,KRT20,HBG2,XPO5,ELP3,LIG4,PSMA1,WWC1,EIF2A,BLOC1S4,C19orf70,HERPUD1,UBE2E1,DNAH14,EXOC6,POP1,MYBBP1A,BICD1,FSCN1,INTS5,EXOC4,RRAGA,PFDN2,TBL1X,PDSS2,AGO3,N4BP2L2,TCF12,SNX27,CHMP2A,PCNT,MYO7A,TNXB,PIGH,SMARCA4,PBX1,DHX35,VPS18,FARSA,BRE,MPHOSPH10,NVL,RPS6KL1,SNTG2,ITGAX,CPSF3,VCL,UTP4,GNG5,HTRA2,AUP1,COL5A2,PTBP2,ATXN1,DKC1,RAB10,HNRNPR,COPS5,ARNTL,SRFBP1,HEATR1,NFRKB,KLHL24,BCKDK,KLC4,PDE4B,H2AFJ,MED18,ATF7IP,MRPS11,CTNNBL1,SCN1B,SEC24C,DCTN4,FBL,AMOT,PKNOX1,TOP1,ARNTL2,PPP1R9B,KDM5A,MEN1,HSPA1B,RERE,WDR35,MPP7,VPS37B,CUL2,NCBP2,POLR1C |
| 1.569e-13 | -29.48 | CAIRO_HEPATOBLASTOMA_CLASSES_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_CLASSES_UP | 580 | 138 | 17758 | 2279 |
THOC5,LYRM4,PRDX6,PTPRA,NAT10,CSNK2A1,NLE1,AARS,PABPC4,CIAPIN1,SMARCB1,RPS16,SRSF2,ATP5G2,THAP4,METTL8,MAD1L1,RAN,FXN,TRIP13,SF3A1,TMPO,GNL3,CDK4,KIF15,PSMG1,MCM2,ODC1,DLST,CLNS1A,CHAF1A,STOML2,SUPT4H1,BRCA2,TRRAP,PQBP1,HIC2,CCNB1IP1,BLMH,MCM6,CCDC47,XPO7,C6orf48,DDX56,EIF2S2,ATIC,TIMELESS,GTF3C3,ALDH18A1,PRMT5,TOMM34,PPA1,SERBP1,EXOSC2,WARS2,RB1CC1,PPAT,USP10,IMPDH2,EPRS,TSR1,UBAP2,MYBBP1A,TASP1,RPL28,TRAP1,RIOK3,GPN1,SQLE,CDKAL1,CNOT6,DDX10,COG5,HS2ST1,BCCIP,DDX18,OLA1,SMARCA4,RSL1D1,IGSF1,KDM1A,NOP56,CAD,CHD7,FARSA,MRPS27,PRMT3,HTRA2,HN1,PMS1,RFC4,DDX41,NPM3,R3HDM1,DKC1,EIF3H,SMARCC1,HNRNPR,COPS5,POLR3E,ACP1,RPS6KB1,HEATR1,PUS1,MDN1,NOLC1,PDCD11,YEATS2,HMGA2,MCM10,SULT1C2,UTP14A,C10orf2,DBF4,APRT,VARS,PSMF1,BZW2,SFI1,POLR3D,GART,NOP16,EXOSC4,FBL,ACTR3B,APEX1,ABCF2,ADSL,TBRG4,PTK2,EIF5B,C8orf33,TPD52L2,NCBP2,TAF12,POLR1C,IPO4,GCSH |
| 1.928e-13 | -29.28 | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | MSigDB lists | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | 791 | 174 | 17758 | 2279 |
PTP4A1,CGN,ADAM19,CNTNAP3,PRKAB2,ENAH,ADAMTS6,MAP2K3,SLC30A7,DST,S100A10,THADA,GPR87,ZNF148,YARS,PTPRK,CHD9,DEAF1,MIOS,CMIP,LIMA1,UPP1,AP4B1,HSPA5,ATG12,MCL1,CAV1,COTL1,DENND4A,PLCXD2,OSBPL1A,SKIL,GLS,SLC7A1,EPN2,AHNAK,HSDL2,SH3RF1,CHD3,ARL4A,TNFRSF1A,HIC2,CLU,RUNX1,DMTF1,C9orf78,JUP,ITPRIP,NHS,SMAD7,GTF2IRD1,SMG7,ZFP36L1,FKBP1A,RSPRY1,ABCA5,INTS7,USPL1,MYC,PPA1,NT5E,FADS1,IFRD1,COL17A1,LAMC1,MYO10,EIF4A2,JMJD1C,TYW1,WBSCR22,WWC1,RNH1,ARID1A,MBNL2,RDH11,TBC1D2,VPS13C,SPAG9,KPNA1,NME7,PDLIM1,PMEPA1,SNAP23,FAT1,RIOK3,PURB,GPN1,PEX13,SH3PXD2A,RTTN,SPRED2,AMOTL1,ID1,ARID2,SLC48A1,COBLL1,MYH9,SPATS2L,PLEK2,TUBB6,FOSL2,RING1,BLOC1S2,DENR,ZBED2,BRE,SLC38A2,MET,VCL,GNG5,LSM10,PERP,PHLDB2,ANTXR2,KRT7,GRHL3,ATXN1,VIM,SLC35F2,AKAP13,SLC35D1,ENC1,DSP,STK10,ZC3H12A,SMAD3,ARHGAP21,MBTD1,ITGA2,HOXA3,ANXA2,DNAJC2,INSIG2,SESTD1,KLC4,NFX1,RTN4,FOXO3,PHLDA2,POGZ,MBNL1,RMI1,NEDD4,SFR1,PRKCH,ABL1,DSG2,MAP3K14,CD44,PNMA1,ACTR3B,WDFY3,ABCF2,RANGAP1,ARHGAP32,PTK2,GPNMB,KLF6,ECH1,UBC,MFN2,HELZ,DSC2,GADD45A,ARID3B,HNRNPH3,ACOX1,TBX3,CSRNP1,EIF2S1,AEN,SVIL,RBPJ,ADK |
| 3.171e-13 | -28.78 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | 1359 | 265 | 17758 | 2279 |
CUL4A,PRDX6,HLTF,SREBF2,S100A10,FXN,GNL3,CLNS1A,STOML2,SPOP,LUC7L3,ARL6IP5,MPV17,XPNPEP1,TPM1,TXN2,BLMH,BMI1,NMD3,KHDRBS1,PLA2G12A,EIF2S2,ATIC,COPS3,MYC,TNPO3,GTF3C3,GEMIN4,PRMT5,AGL,PRPS1,ANGPT2,FDFT1,HMGCR,SCAF11,FADS1,IFRD1,WDR61,RREB1,SIGMAR1,PCCA,PTPN12,MBNL2,MTR,ARIH2,SEC31A,MTHFD2,NME7,SQLE,NCOR1,PDLIM5,HS2ST1,BTBD2,ATP6V1A,ACTR3,UROD,NDUFB5,STAM,TERF2IP,DECR1,PRKD3,PPID,UCHL5,NT5C,SSBP1,CMPK1,CASP8AP2,PMS1,RFC4,GARS,RFC3,MTIF2,NPM3,EIF3J,PCMT1,PNN,MARCH6,FKBP3,SNCA,TAF2,BAZ1A,CDC16,SMARCC1,DNAJA3,ALKBH1,ACP1,NOLC1,TROVE2,XPC,SF3A3,FARS2,RTN4,MLH1,IKBKAP,INPP1,FOXO3,FAM8A1,PSMF1,TADA3,ABL1,SNW1,CFDP1,PTGS1,PNMA1,NUDC,TBRG4,UBE2K,RPA1,ANXA1,OXSR1,ETFDH,POLE2,ORC5,ADK,SLC43A1,TRIM16,ATRX,PTPRA,WDR13,CSNK2A1,SLC29A1,BIRC2,MRPS30,AMPD3,ANAPC1,SRSF2,RAP1A,COPS4,ANAPC10,POLE3,YARS,MPST,PRKACB,SRPK2,SF3A1,CDC37,DEAF1,TRIM13,ABCC4,ITPA,GMFB,ATG12,MARCKSL1,PSMG1,PITPNB,BRCA1,KCNH2,ODC1,MLLT10,ARPC3,YTHDF2,PEX1,UBTF,HPRT1,LSS,EIF4ENIF1,SEPHS2,SARS,AK2,PIGN,LAMTOR3,ZFP36L1,NAMPT,SUB1,VPS72,GTF2H1,GMDS,ALDH18A1,MTHFD1,NIPSNAP1,NAA38,CRADD,PPAT,TRA2A,WBSCR22,TBXAS1,PSMA1,UBE2E1,PGD,PWP1,UBAP2,FSCN1,SNAP23,FDPS,TBPL1,HK2,RRAGA,SLC16A1,TBL1X,HMBS,IFITM2,PTP4A2,DDX10,NAPA,TCF12,NDUFA5,FEZ2,SUCLG1,PSTPIP2,SLC2A1,LPCAT3,CAD,SLC38A2,HIBCH,BCAP29,ETF1,AHCYL1,VCL,HTRA2,AUP1,CASP10,PRPF19,ACSL5,KDM3B,AKAP8L,SSFA2,DDX41,TFCP2,CPOX,ATXN1,DKC1,PLIN2,RANBP2,RBBP8,KPNA3,ALAD,HNRNPR,COPS5,TIMM17A,SLC25A11,FKBP5,RNF130,PUS1,USP11,DBF4,VARS,CSNK1A1,IQGAP2,ADH5,GART,CTNNBL1,ANXA7,DCTN4,SHMT2,CLDND1,PCK2,HSD17B12,TOP1,ARNTL2,KDM5B,FOXN3,ABCF2,RAP1GDS1,RANGAP1,MEN1,PIK3CB,TARS,ALG5,DNAJC12,NCBP2,RBM26,RBPJ,POLR1C,RPS6KC1,GCSH |
| 3.818e-13 | -28.59 | cellular biosynthetic process | biological process | GO:0044249 | 4514 | 728 | 16441 | 2138 |
GGT1,ASCC1,DPH1,AARS2,MRPL10,CACNA1H,HLTF,CCNL2,ZNF44,NUP160,SYNJ1,PABPC4,SKI,ZNF37A,MMP7,SREBF2,IKZF5,ZFHX3,ATP5G2,ZNF148,KDM5C,ZNRD1,FXN,HMBOX1,EIF4E3,RNMT,UPP1,NFIA,RFX2,C5AR1,MCM2,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,RAD18,BDH2,RUNX1,ZNF532,RBP1,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,PIK3R4,PLA2G12A,RSF1,CDC73,YARS2,EIF2S2,MCM5,ZNF326,MED24,MRPL21,PRMT5,ZNF518B,AGL,COQ3,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,FADS1,GTF2H3,ALG6,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,SMARCD3,ST6GALNAC3,IMPDH2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,GSTO2,NME7,RPL28,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,ST3GAL6,SAFB2,LCLAT1,MCM9,ZKSCAN1,PYCRL,WAC,ATRIP,GSTA4,MGLL,MTHFD2L,LSM10,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,MAT2A,FGFR1,TAF2,KDM4B,ELP2,PEMT,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,SERINC5,TRAK1,ID2,JMJD6,TRIM22,BHLHE40,TGFB2,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ACOT11,PTGS1,ZNF710,RPL22L1,SOX6,POLK,MRPS10,ZNF467,FOXC1,UBC,MRPL36,RPA1,TRIB3,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,SRD5A3,GPAM,MTMR1,KDM4C,SRM,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,SEC16A,COX10,BIRC2,AMPD3,SRSF2,PHF5A,HKR1,PPCDC,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,MPST,CHD9,ZNF124,ATF4,AEBP2,GCNT2,PPARG,HARS,BAZ2A,ZNF414,MED27,COL4A3BP,ATG12,BRCA1,ODC1,ZNF91,MGST1,MLLT10,GLS,HPRT1,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,DLX2,BEND6,SEPHS2,SARS,MCM6,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,SYNJ2,ALDH18A1,GMDS,PNPLA3,NT5E,WARS2,TRAPPC9,PAXBP1,TLE3,SETD2,TRAPPC6B,SUPT5H,VAC14,TCF7L2,NR2F1,PWP1,ATXN7,TBPL1,ZNF430,DTD1,HMBS,GGT7,NAPA,MPI,ID1,SUCLG1,ARID2,LPCAT2,RPS29,SLC2A1,ZNF83,LPCAT3,ZNF709,TNKS1BP1,PELP1,ZNF121,RPAIN,FDX1,KDM1A,DENR,CAD,NRF1,ZBTB21,IDI1,NUP133,ZDHHC6,RNF2,ETF1,ZFP37,SEC24A,KAT8,KDM3B,PCGF3,NARS,CPOX,NUP214,ZNF251,EIF3H,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ABHD3,ATG7,ZNF436,MED20,ZNF18,EIF2B3,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,ZNF561,SELT,CPNE7,POLR1B,HSD17B12,SNAPC5,TRNP1,GINS3,FOXN3,ZNF654,ZMYM5,PIK3CB,NEU1,POLR3A,ZRANB3,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,POLB,CUL4A,PRKCSH,PRKAB2,GYG1,GABPB2,AARS,LPIN1,MGA,RPS16,RNF111,CHD2,DPH6,ME1,MEIS3,FUT11,SEH1L,CSGALNACT2,ZNF646,DPF3,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,ZDHHC14,DENND4A,SAP30BP,GZF1,SKIL,DDAH2,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,LARS2,ZHX3,ST6GAL1,GTF2IRD1,DPM3,SSR4,CHD5,IGF2BP3,HR,PI4KB,ENTPD5,ZNF586,SCAF1,ATIC,MYC,PIGG,GTF3C3,LPCAT1,PRPS1,TERF2,FDFT1,RREB1,PRIM2,POLA1,RDH10,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,DAGLA,SEC31A,ASCC3,EPRS,MTHFD2,NSF,HIF1A,VCAN,SRP68,SPEN,MED15,ZBTB12,PURB,UMPS,NCOR1,CNDP2,ZFHX2,HS2ST1,ZNF254,ZBTB37,UROD,FOSL2,RING1,TERF2IP,FLAD1,CHD7,ZNF827,SLX4,ASNS,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,CMPK1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,SERP1,HSD3B7,ZBTB25,SNCA,TAMM41,VDR,BAZ1A,DNTTIP1,MSX2,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,LARGE,TROVE2,NCOR2,C10orf2,B4GALT5,MRI1,TCF3,ZNF280C,NFX1,FARS2,MYNN,LIAS,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,HARS2,YBX3,NT5M,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,AGPAT4,ADSL,KLF6,GUF1,MMAA,POLR2A,ZFP62,ZNF155,ZDHHC11,COQ9,ORC5,ATM,ADK,DDIT3,KAT6A,ZNF76,PIGM,PHF3,MVK,EIF3C,ATRX,KMT2E,RARS2,CERS5,RCHY1,ZNF107,PLOD1,BCOR,SIRT2,SNAPC4,SMARCB1,MRPS30,SRPRB,CNIH3,YLPM1,JAZF1,RELB,ZEB1,POLR3B,SLC35C2,SLC27A5,GALNT18,YARS,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,GPCPD1,MINA,HDAC8,PITPNB,MTHFD1L,ZSCAN2,SOX4,KMT2C,ST3GAL5,CHAF1A,TAF9B,UBTF,PAF1,GATA6,CC2D1B,MKL2,CTAGE5,PQBP1,CRCP,GALNT10,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,CHST11,PIGN,AK2,TAF1,SEC24D,PAX2,DPF2,GPAT3,ALG8,MED13L,PHGDH,DDIT4,NAMPT,ELL,ZNF354A,ISPD,NRIP1,POLR1E,MTHFD1,ZNF629,VOPP1,ZNF234,TSTA3,PPAT,ELOVL6,JMJD1C,ELP3,TBXAS1,WBSCR22,ZFP14,WWC1,LIG4,PRDM1,EIF2A,TMEM241,ISG15,MGAT2,MYBBP1A,FDPS,RRAGA,CDKAL1,ZFP90,TBL1X,PDSS2,NR2C2AP,ZBTB24,TCF12,ASH1L,PIGH,SMARCA4,PBX1,ZSCAN5A,FARSA,RRN3,CAMTA2,CBR4,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,TMLHE,MAML3,NARS2,ACSL5,PRAME,TFCP2,PARP2,SFSWAP,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,WARS,BATF3,TPK1,ALAD,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,DBF4,PPHLN1,CHCHD10,ATF7IP,MED18,PIP4K2A,GFM2,MAN1A1,MRPS11,PEX7,GART,HAS3,SEC24C,SHMT2,DMRT1,PKNOX1,SLC25A1,RPS6KB2,TOP1,ARNTL2,MSX1,GPHN,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,ZNF324B,SCMH1,MARS,MEN1,ZNF407,EIF5B,TARS,ZNF221,RERE,ZNF708,ALG5,SERINC1,DAGLB,NCBP2,POLR1C,NFKBIB |
| 1.073e-12 | -27.56 | organic substance biosynthetic process | biological process | GO:1901576 | 4614 | 739 | 16441 | 2138 |
GGT1,ASCC1,AARS2,MRPL10,CACNA1H,HLTF,CCNL2,ZNF44,NUP160,SYNJ1,PABPC4,SKI,ZNF37A,MMP7,SREBF2,IKZF5,ZFHX3,ATP5G2,ZNF148,KDM5C,ZNRD1,FXN,HMBOX1,EIF4E3,RNMT,UPP1,NFIA,RFX2,C5AR1,MCM2,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,RAD18,BDH2,RUNX1,ZNF532,RBP1,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,PIK3R4,PLA2G12A,RSF1,CDC73,YARS2,EIF2S2,MCM5,ZNF326,MED24,MRPL21,PRMT5,ZNF518B,AGL,COQ3,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,FADS1,GTF2H3,ALG6,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,SMARCD3,ST6GALNAC3,IMPDH2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,GSTO2,NME7,RPL28,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,ST3GAL6,SAFB2,LCLAT1,MCM9,ZKSCAN1,PYCRL,WAC,ATRIP,GSTA4,MGLL,MTHFD2L,LSM10,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,MAT2A,FGFR1,TAF2,KDM4B,ELP2,PEMT,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,SERINC5,INSIG2,TRAK1,ID2,JMJD6,TRIM22,BHLHE40,TGFB2,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ACOT11,PTGS1,ZNF710,RPL22L1,SOX6,POLK,MRPS10,ZNF467,FOXC1,UBC,MRPL36,RPA1,TRIB3,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,SRD5A3,GPAM,MTMR1,KDM4C,SRM,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,SEC16A,COX10,BIRC2,AMPD3,SRSF2,PHF5A,HKR1,PPCDC,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,CHD9,ZNF124,ATF4,AEBP2,GCNT2,PPARG,HARS,BAZ2A,ZNF414,MED27,COL4A3BP,ATG12,BRCA1,ODC1,ZNF91,MGST1,MLLT10,GLS,LSS,HPRT1,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,DLX2,BEND6,SEPHS2,XYLB,SARS,MCM6,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,SYNJ2,ALDH18A1,GMDS,PNPLA3,NT5E,WARS2,TRAPPC9,PAXBP1,TLE3,SETD2,TRAPPC6B,SUPT5H,VAC14,TCF7L2,NR2F1,PGD,PWP1,ATXN7,TBPL1,ZNF430,DTD1,HMBS,GGT7,NAPA,MPI,ID1,SUCLG1,ARID2,LPCAT2,RPS29,SLC2A1,ZNF83,LPCAT3,ZNF709,TNKS1BP1,PELP1,ZNF121,RPAIN,FDX1,KDM1A,DENR,CAD,NRF1,ZBTB21,IDI1,NUP133,ZDHHC6,RNF2,ETF1,ZFP37,PRPF19,SEC24A,KAT8,KDM3B,PCGF3,NARS,CPOX,NUP214,ZNF251,EIF3H,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ABHD3,ATG7,ZNF436,MED20,ZNF18,EIF2B3,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,ZNF561,SELT,CPNE7,POLR1B,PCK2,HSD17B12,SNAPC5,TRNP1,GINS3,FOXN3,ZNF654,ZMYM5,PIK3CB,NEU1,POLR3A,ZRANB3,POLR3G,GPC2,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,MYCBP2,CUL4A,PRKCSH,PRKAB2,GYG1,GABPB2,AARS,LPIN1,MGA,RPS16,RNF111,CHD2,ME1,MEIS3,FUT11,SEH1L,CSGALNACT2,ZNF646,DPF3,SETD1B,NR6A1,NOL8,EYA3,TCEB3,CUX1,ZDHHC14,DENND4A,SAP30BP,GZF1,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,LARS2,ZHX3,ST6GAL1,GTF2IRD1,DPM3,SSR4,CHD5,IGF2BP3,HR,PI4KB,ENTPD5,ZNF586,SCAF1,ATIC,MYC,PIGG,GTF3C3,LPCAT1,PRPS1,TERF2,FDFT1,RREB1,PRIM2,POLA1,RDH10,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,SEC31A,ASCC3,EPRS,MTHFD2,NSF,HIF1A,VCAN,SRP68,SPEN,MED15,ZBTB12,PURB,SQLE,UMPS,NCOR1,CNDP2,DHCR7,ZFHX2,HS2ST1,ZNF254,ZBTB37,UROD,FOSL2,RING1,TERF2IP,FLAD1,CHD7,ZNF827,SLX4,ASNS,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,CMPK1,SERPINH1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,SERP1,HSD3B7,ZBTB25,SNCA,TAMM41,VDR,BAZ1A,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,LARGE,TROVE2,NCOR2,C10orf2,B4GALT5,MRI1,TCF3,ZNF280C,NFX1,FARS2,SLC25A12,MYNN,LIAS,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,HARS2,YBX3,NT5M,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,AGPAT4,ADSL,KLF6,GUF1,MMAA,POLR2A,ZFP62,ZNF155,ZDHHC11,COQ9,ORC5,ATM,ADK,DDIT3,KAT6A,ZNF76,PIGM,PHF3,MVK,EIF3C,ATRX,KMT2E,RARS2,CERS5,RCHY1,ZNF107,PLOD1,BCOR,SIRT2,SNAPC4,SMARCB1,MRPS30,SRPRB,CNIH3,YLPM1,JAZF1,RELB,HYAL1,ZEB1,POLR3B,SLC35C2,SLC27A5,GALNT18,YARS,TRIP13,CARM1,PRKACB,ELOF1,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,GPCPD1,MINA,HDAC8,PITPNB,MTHFD1L,ZSCAN2,SOX4,KMT2C,ST3GAL5,CHAF1A,TAF9B,UBTF,PAF1,GATA6,CC2D1B,MKL2,CTAGE5,PQBP1,CRCP,GALNT10,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,CHST11,PIGN,AK2,TAF1,SEC24D,PAX2,DPF2,GPAT3,ALG8,MED13L,PHGDH,DDIT4,NAMPT,ELL,ZNF354A,ISPD,NRIP1,POLR1E,MTHFD1,ZNF629,VOPP1,ZNF234,TSTA3,PPAT,ELOVL6,JMJD1C,ELP3,TBXAS1,WBSCR22,ZFP14,WWC1,LIG4,PRDM1,EIF2A,TMEM241,ISG15,MGAT2,MYBBP1A,FDPS,RRAGA,CDKAL1,ZFP90,TBL1X,PDSS2,NR2C2AP,ZBTB24,TCF12,ASH1L,CEMIP,PIGH,SMARCA4,PBX1,ZSCAN5A,FARSA,RRN3,CAMTA2,CBR4,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,MAML3,TMLHE,NARS2,ACSL5,PRAME,TFCP2,PARP2,SFSWAP,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,WARS,BATF3,TPK1,ALAD,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SLC25A11,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,DBF4,PPHLN1,MED18,CHCHD10,ATF7IP,PIP4K2A,GFM2,MAN1A1,MRPS11,PEX7,GART,HAS3,SEC24C,SHMT2,DMRT1,PKNOX1,SLC25A1,TOP1,RPS6KB2,ARNTL2,MSX1,GPHN,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,ZNF324B,SCMH1,MARS,MEN1,ZNF407,EIF5B,TARS,ZNF221,RERE,ZNF708,ALG5,SERINC1,NCBP2,POLR1C,NFKBIB |
| 1.104e-12 | -27.53 | ovary | COSMIC cancer mutations | ovary | 15550 | 2092 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,MIOS,CDK4,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,BRAF,RCAN1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,SDCBP2,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,BCKDK,ARL15,KLC4,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,ZNF324B,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,CACNA1H,NUP160,SYNJ1,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,ATG12,FLVCR1,GLS,ZNF622,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,PRICKLE2,CD44,HSD17B12,ADAMTSL3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,ZFAND3,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,GAS6,PSMF1,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,RPS29,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,NR2C2AP,SNX27,CHMP2A,FEZ2,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,FAAH2,RASSF3,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,LRRC28,MEX3A,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.390e-12 | -27.30 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | 2630 | 452 | 17775 | 2278 |
ARHGAP26,CGN,ADAM19,PRDX6,PRKCA,ABHD6,LPAR3,UBR5,MGA,SKI,PDZD2,ZFHX3,SYN2,RABGAP1L,MAD1L1,CHD2,KDM5C,FXN,AVEN,FTSJ3,CNTNAP3B,NRAS,PTPRM,C2orf76,ALDH1L2,EHMT1,CUX1,AKAP12,ABCC2,PLEKHM3,C10orf76,ZDHHC14,SON,GNAI1,OSBPL1A,STOML2,DLEU1,AHNAK,BRCA2,TRRAP,RAD18,SH3RF1,VPS13D,SEMA3C,RUNX1,NRP1,WDR66,BLMH,ZNF532,PTPN14,EFNB2,HERC2,EP400,C9orf78,WDR75,DROSHA,CELSR1,ANKRD17,LARS2,CCDC53,TRIO,NHS,OPHN1,PID1,TGFBR2,CD226,ANXA10,IGF2BP3,RBM20,PRKCE,CNST,KIAA1671,APLF,ASAP1,ZNF326,SAMD13,GEMIN4,MAP3K12,PABPC1,FMNL2,ZNF675,SIK3,EXOSC2,STAG1,SYNGAP1,PRIM2,KCNQ3,RB1CC1,PRDM16,POLA1,RAPGEF4,EPS15L1,RYR2,ST6GALNAC3,PLCB1,EVI5,MBNL2,MTR,ASCC3,VPS13C,LRP1B,NME7,VCAN,SPEN,ZZEF1,MED15,PURB,MACROD1,PDLIM5,ARHGAP10,SGSM3,RTTN,SYT17,DNM3,ZNF516,TRERF1,VTI1A,OLA1,CD99L2,SPATS2L,PLEK2,PTPRG,SAFB2,EEA1,PDE3A,CHD7,DECR1,CD96,ZNF827,ABCA12,ERI1,TBC1D22A,SETD5,MRPS27,DTNBP1,CLCN6,NBEA,CMPK1,CEP63,MGLL,ZC3H3,ATP6AP1L,DENND1A,LYST,WDPCP,FAM171A2,PREX1,TTC28,DSP,STK10,ERC1,HSD3B7,DHX57,PDE8B,HTR7,ZFAND3,BAZ1A,FBXL5,CAMK2D,ARHGAP21,IQCH,CDC16,KDM4B,ASTN2,NSMCE2,CAMKMT,WDR7,LARGE,SLC4A7,ANXA2,PDCD11,ANKS1A,METTL2B,MID1,LRCH1,HMGA2,BRAF,SCAMP3,TTC27,ZNF280C,NFX1,FARS2,WDR37,RCAN1,MLH1,RSRC1,MBNL1,ZNF483,TAF3,CFDP1,UNC13A,COPS7B,C15orf41,SOX6,DIS3L2,CLK2,FER1L5,TTLL5,CLYBL,WDFY3,TMEM126B,NXN,TBRG4,CCDC113,GUF1,SLC23A2,PXDN,IREB2,HELZ,STX18,ATM,SLCO5A1,SVIL,PTPN4,MYOM2,BRWD3,ADK,MTMR1,DOCK6,CORO2B,IMMP2L,BCAS4,LYRM4,RBM33,ATRX,NF1,TFIP11,PPARGC1B,SLC25A21,ANKRD18A,BCOR,FAM13A,STK33,COX10,SCAF8,AHCYL2,RTN1,ZNF804A,ARHGAP18,PHKA1,THADA,JAZF1,B3GNTL1,POLR3B,CEP128,PTPRK,VPS13B,TMPO,FAM184A,GPM6A,FBXW4,ABCC4,ZNF195,CMIP,ANK2,MED27,GDPD1,NOL6,KSR2,LAMA2,COTL1,MTHFD1L,SGK2,ZSCAN2,FLVCR1,CRYBG3,SERGEF,KIF16B,TAF9B,YTHDF2,CHAF1A,CCDC3,TMEM132B,GEMIN5,TCF7L1,MSRA,DNAJC1,CC2D1B,CHD3,EEFSEC,FAM114A2,CCDC146,MKL2,CSMD3,DPP4,ABCC3,GALNT10,DLX2,MTCH1,CHMP4C,SLC12A7,XYLB,FN1,ITFG1,STXBP6,PRSS3,SMG7,RHBDD1,DOPEY1,RNF40,SIPA1L3,ATXN2,SAMD11,PPIL2,VAPB,CCDC167,SYNJ2,GMDS,PNPLA3,SNX29,ZNF629,MTHFD1,VOPP1,TRAPPC9,CRADD,TSTA3,PPAT,XPO5,UTP15,WDR25,OBSCN,C11orf65,CORIN,SYT1,AGAP1,HERPUD1,TCF7L2,GRIK4,SYNCRIP,KIAA0355,FAT1,SDCCAG8,EXOC4,TMEM117,SLC16A1,CASS4,CDKAL1,DDX10,SH3PXD2A,DMXL2,TCF12,USP7,CHMP2A,PCNT,ARID2,NDUFAF2,GPR143,COBLL1,ST7L,ARSJ,GBF1,DHX35,RIOK2,ZNF608,BRE,NUP133,ARMC5,ZDHHC6,SNTG2,ANO8,MYH15,FHIT,ADCK4,ITGAX,CTC1,MCEE,ACSL5,KDM3B,PCGF3,COL5A2,AKAP8L,FAM172A,THSD4,ANKRD33B,PARP2,NLN,VIM,AKAP13,DKC1,ENC1,EDEM2,UBR4,TPK1,BTBD11,LMBR1L,ZNF557,CLEC16A,ABHD3,ATG7,TSSC1,SRFBP1,PRRT3,SMG1,PARD3,ZNF507,TMCC1,ATXN7L2,TNIK,AUH,SULT1C2,MAP3K13,FAM46B,DYM,ARL15,NSUN6,CLSTN2,ARFIP2,SEMA3E,PPP1R1C,RBM19,BMP6,IQGAP2,PTPN2,SACS,CWC27,SEC24C,PRICKLE2,SELT,FBL,ERI3,DMRT1,HSD17B12,MARCH9,LRRIQ1,CRIM1,ANKMY2,FERMT2,ARHGEF12,PDE2A,PALLD,ZNF407,NAALADL2,CHCHD6,PIK3CB,POLR3A,RERE,MKX,POLR3G,CENPP,CTIF,ZNF708,SAMD5,NOL10,MPP7,AGTPBP1,TAF4,TBX3,BCAS3,PREPL,RPS6KC1,KIF1B,MMP16 |
| 1.446e-12 | -27.26 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 16720 | 2211 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RASSF3,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.493e-12 | -27.23 | RNA_METABOLIC_PROCESS | MSigDB lists | RNA_METABOLIC_PROCESS | 827 | 177 | 17758 | 2279 |
ZNF76,UBN1,ATRX,PPARGC1B,BCOR,SNAPC4,AARS,GABPB2,PABPC4,MAP2K3,SMARCB1,SRSF2,SREBF2,PHF5A,ZFHX3,JAZF1,ZEB1,ZNF148,CHD2,ETV1,HCFC2,YARS,TRIP13,CARM1,SF3A1,SRPK2,METTL1,DEAF1,ATF4,NR6A1,RNMT,PPARG,MED27,CUX1,TCEB3,HDAC8,BRCA1,SPOP,UBTF,GEMIN5,SKIL,DYRK1B,SUPT4H1,GATA6,SUFU,CCNT1,CHD3,LUC7L3,MKL2,PQBP1,TNFRSF1A,RUNX1,SARS,FOXO1,ZHX3,PRPF31,KHDRBS1,PAX2,SMG7,RSF1,PARN,IGF2BP3,ELL,SUB1,ZNF354A,INTS7,VPS72,MYC,BUD31,GTF2H1,MED24,GEMIN4,NRIP1,POLR1E,PABPC1,CPSF3L,SCAF11,EXOSC2,PRIM2,RREB1,TRA2A,JMJD1C,ELP3,ARID5B,SMARCD3,PRDM1,ARID1A,SUPT5H,TCF7L2,POP1,MYBBP1A,BICD1,SYNCRIP,HIF1A,INTS5,CDK9,NCOR1,ZNF254,TCF12,ASH1L,TRERF1,NPAS2,RBFOX2,PBX1,FOSL2,HSPA1A,NOP56,NRF1,RRN3,BCAS2,INTS12,CPSF3,MAML3,TFCP2,SFSWAP,MED16,DKC1,WARS,BATF3,TAF2,SMAD3,RBBP8,ELP2,SMARCC1,HNRNPR,COPS5,KLF4,ARNTL,CEBPZ,INTS9,MED20,NFRKB,NOLC1,TROVE2,SMG1,HMGA2,AUH,TCF3,TRAK1,NFX1,FARS2,SF3A3,ATF7IP,TRIM22,IKBKAP,NOL3,ZNF346,RPS6KA5,FOXO3,BMP6,ABL1,TADA3,SNW1,PTRF,UPF2,CELF1,FBL,SNAPC5,APEX1,KDM5B,FOXN3,KDM5A,MEN1,NOP58,HSPA1B,POLR3G,NSD1,SRCAP,RARS,HNRNPH3,TBX3,NCBP2,ZRANB2,RBPJ,NR2F2,POLR1C,DDIT3 |
| 1.562e-12 | -27.19 | biosynthetic process | biological process | GO:0009058 | 4694 | 749 | 16441 | 2138 |
GGT1,ASCC1,DPH1,AARS2,MRPL10,CACNA1H,HLTF,CCNL2,ZNF44,NUP160,SYNJ1,CIAPIN1,PABPC4,SKI,ZNF37A,MMP7,SREBF2,IKZF5,ZFHX3,ATP5G2,ZNF148,KDM5C,ZNRD1,FXN,HMBOX1,EIF4E3,RNMT,UPP1,NFIA,RFX2,C5AR1,MCM2,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,BRCA2,SUPT4H1,RAD18,BDH2,RUNX1,ZNF532,RBP1,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,PIK3R4,PLA2G12A,RSF1,CDC73,YARS2,EIF2S2,MCM5,ZNF326,MED24,MRPL21,PRMT5,ZNF518B,AGL,COQ3,PABPC1,PPA1,MYB,HMGCR,ZNF675,GATAD2B,FADS1,GTF2H3,ALG6,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,SMARCD3,ST6GALNAC3,IMPDH2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,GSTO2,NME7,RPL28,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,ST3GAL6,SAFB2,LCLAT1,MCM9,ZKSCAN1,PYCRL,WAC,ATRIP,GSTA4,MGLL,MTHFD2L,LSM10,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,MAT2A,FGFR1,TAF2,KDM4B,ELP2,PEMT,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,SERINC5,INSIG2,TRAK1,ID2,JMJD6,TRIM22,BHLHE40,TGFB2,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ACOT11,PTGS1,ZNF710,RPL22L1,SOX6,POLK,MRPS10,ZNF467,FOXC1,UBC,MRPL36,RPA1,TRIB3,NSD1,RARS,SRCAP,BAZ2B,POLE2,ARID3B,SRD5A3,GPAM,MTMR1,KDM4C,SRM,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,SEC16A,COX10,BIRC2,AMPD3,SRSF2,PHF5A,HKR1,PPCDC,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,MPST,CHD9,ZNF124,ATF4,AEBP2,GCNT2,PPARG,HARS,BAZ2A,ZNF414,MED27,COL4A3BP,ATG12,BRCA1,ODC1,ZNF91,MGST1,MLLT10,GLS,LSS,HPRT1,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,DLX2,BEND6,SEPHS2,XYLB,SARS,MCM6,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,SYNJ2,ALDH18A1,GMDS,PNPLA3,NT5E,WARS2,TRAPPC9,PAXBP1,TLE3,SETD2,TRAPPC6B,SUPT5H,VAC14,TCF7L2,NR2F1,PGD,PWP1,ATXN7,TBPL1,ZNF430,DTD1,HMBS,GGT7,NAPA,MPI,ID1,SUCLG1,ARID2,LPCAT2,RPS29,SLC2A1,GPR143,ZNF83,LPCAT3,ZNF709,TNKS1BP1,PELP1,ZNF121,RPAIN,FDX1,KDM1A,DENR,CAD,NRF1,ZBTB21,IDI1,NUP133,ZDHHC6,RNF2,ETF1,ZFP37,PRPF19,SEC24A,KAT8,KDM3B,PCGF3,NARS,CPOX,NUP214,ZNF251,EIF3H,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ABHD3,ATG7,ZNF436,MED20,ZNF18,EIF2B3,ZNF507,NIFK,MCM10,RFX1,AGO2,APRT,VARS,FOXP1,RMI1,ZNF594,ZNF561,SELT,CPNE7,POLR1B,PCK2,HSD17B12,SNAPC5,TRNP1,GINS3,FOXN3,ZNF654,ZMYM5,PIK3CB,NEU1,POLR3A,ZRANB3,POLR3G,GPC2,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,POLB,CUL4A,PRKCSH,PRKAB2,GYG1,GABPB2,AARS,LPIN1,MGA,RPS16,RNF111,CHD2,DPH6,ME1,MEIS3,FUT11,SEH1L,CSGALNACT2,ZNF646,DPF3,SETD1B,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,ZDHHC14,DENND4A,SAP30BP,GZF1,SKIL,DDAH2,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,LARS2,ZHX3,ST6GAL1,GTF2IRD1,DPM3,SSR4,CHD5,IGF2BP3,HR,PI4KB,ENTPD5,ZNF586,SCAF1,ATIC,MYC,PIGG,GTF3C3,LPCAT1,PRPS1,TERF2,FDFT1,RREB1,PRIM2,POLA1,RDH10,ARID1A,NELFA,MTR,ZNF850,PHF6,ZNF425,DAGLA,SEC31A,ASCC3,EPRS,MTHFD2,NSF,HIF1A,VCAN,SRP68,SPEN,MED15,ZBTB12,PURB,SQLE,UMPS,NCOR1,CNDP2,DHCR7,ZFHX2,HS2ST1,ZNF254,ZBTB37,UROD,FOSL2,RING1,TERF2IP,FLAD1,CHD7,ZNF827,SLX4,ASNS,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,CMPK1,SERPINH1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,SERP1,HSD3B7,ZBTB25,SNCA,VDR,TAMM41,BAZ1A,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,LARGE,TROVE2,NCOR2,C10orf2,B4GALT5,MRI1,TCF3,ZNF280C,NFX1,FARS2,SLC25A12,MYNN,LIAS,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,HARS2,YBX3,NT5M,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,AGPAT4,ADSL,KLF6,GUF1,MMAA,POLR2A,ZFP62,ZNF155,ZDHHC11,COQ9,ORC5,ATM,ADK,DDIT3,KAT6A,ZNF76,PIGM,PHF3,MVK,EIF3C,ATRX,KMT2E,RARS2,CERS5,RCHY1,ZNF107,PLOD1,BCOR,SIRT2,SNAPC4,SMARCB1,MRPS30,SRPRB,CNIH3,YLPM1,JAZF1,RELB,ZEB1,HYAL1,POLR3B,SLC35C2,SLC27A5,GALNT18,YARS,TRIP13,CARM1,PRKACB,ELOF1,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,GPCPD1,MINA,HDAC8,PITPNB,MTHFD1L,ZSCAN2,SOX4,KMT2C,ST3GAL5,CHAF1A,TAF9B,UBTF,PAF1,GATA6,CC2D1B,MKL2,CTAGE5,PQBP1,CRCP,GALNT10,ZC3H8,ZNF397,NOCT,DMTF1,EMSY,PIGN,CHST11,AK2,TAF1,SEC24D,PAX2,DPF2,GPAT3,ALG8,MED13L,PHGDH,DDIT4,NAMPT,ELL,ZNF354A,ISPD,NRIP1,POLR1E,MTHFD1,ZNF629,VOPP1,ZNF234,TSTA3,PPAT,ELOVL6,JMJD1C,ELP3,TBXAS1,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,EIF2A,TMEM241,ISG15,MGAT2,MYBBP1A,FDPS,RRAGA,CDKAL1,ZFP90,TBL1X,PDSS2,NR2C2AP,ZBTB24,TCF12,ASH1L,CEMIP,PIGH,SMARCA4,PBX1,GBF1,ZSCAN5A,FARSA,RRN3,CAMTA2,CBR4,ZNF142,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,MAML3,TMLHE,NARS2,ACSL5,PRAME,TFCP2,PARP2,SFSWAP,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,WARS,BATF3,TPK1,ALAD,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SLC25A11,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,DBF4,PPHLN1,MED18,CHCHD10,ATF7IP,PIP4K2A,GFM2,MAN1A1,MRPS11,PEX7,GART,HAS3,SEC24C,SHMT2,DMRT1,PKNOX1,SLC25A1,TOP1,RPS6KB2,ARNTL2,MSX1,GPHN,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,ZNF324B,SCMH1,MARS,MEN1,EIF5B,ZNF407,TARS,ZNF221,RERE,ZNF708,ALG5,SERINC1,DAGLB,NCBP2,POLR1C,NFKBIB |
| 1.736e-12 | -27.08 | BMI1 (BMI1 proto-oncogene, polycomb ring finger) | protein interactions | 648 | 357 | 101 | 16036 | 2270 |
USP7,PHF3,ACTG1,RBFOX2,TFIP11,PLRG1,AARS2,NAT10,SMARCA4,PPIL1,SAFB2,EEA1,HSPA1A,UBL5,PABPC4,RING1,ZC3H13,PHC2,PHF5A,YLPM1,SLC39A7,UBAP2L,RNF2,KMT2A,TIMM50,SRPK2,DBN1,SNU13,PCGF3,AKAP8L,LIMA1,SKIV2L2,EHMT1,NOL6,DKC1,SON,PYCR1,SPOP,YTHDF2,GEMIN5,RANBP2,SMARCC1,CHD3,ADNP,LUC7L3,H2AFX,SLC25A11,FUS,HEATR1,USP11,PDCD11,BMI1,DROSHA,SUPT6H,ZCCHC8,KHDRBS1,C10orf2,DPF2,AGO2,PPHLN1,NFX1,CEP126,SSR4,PHGDH,ENOX1,GIGYF2,RSRC1,YARS2,SNW1,ATXN2,BUD31,ZNF326,GEMIN4,CELF1,FBL,YBX3,TERF2,DIS3L2,SCAF11,ADARB1,MSI2,PAXBP1,PSPC1,TRA2A,SCMH1,LENG8,MBNL2,NOP58,PHF6,DYNC1H1,MYBBP1A,HELZ,SPEN,ATM,PURB,NCBP2,PGAM5,WDR33,PDLIM5,SRP14,RNF114 |
| 1.852e-12 | -27.01 | kidney | COSMIC cancer mutations | kidney | 16177 | 2157 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,ELP5,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,ANTXR2,ATXN1,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,KLC4,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,ATRIP,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,ZNF430,PRKAR2A,KCTD7,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WWC1,ANKRD20A4,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,LAMA2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,PLAC8L1,FERMT2,RANGAP1,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,C16orf52,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,UNC13D,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TBXAS1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 3.101e-12 | -26.50 | PUJANA_BRCA1_PCC_NETWORK | MSigDB lists | PUJANA_BRCA1_PCC_NETWORK | 1581 | 295 | 17758 | 2279 |
POLB,GNB3,ADAM19,CUL4A,DDX19A,HLTF,PRKCA,NUP160,UBR5,PABPC4,CIAPIN1,ZNF37A,PMAIP1,RABGAP1L,PDS5B,SUCLG2,ME1,CEP135,FXN,NRAS,WDHD1,MCM2,MAK16,CLNS1A,STOML2,PYCR1,SLC7A1,ZNF266,BRCA2,LSM14A,XPNPEP1,RUNX1,BLMH,P2RY11,EP400,LARS2,PRPF31,KHDRBS1,CLINT1,PARN,IGF2BP3,EIF2S2,ATIC,COPS3,MCM5,MYC,MED24,TNPO3,ANP32B,GEMIN4,PRPS1,TOMM34,PABPC1,SERBP1,HMGCR,FDFT1,MYB,FADS1,GTF2H3,RREB1,RB1CC1,POLA1,AOC2,RAP1B,TTYH2,USP10,IMPDH2,ARID1A,CPT1A,MTR,ARIH2,EPRS,TSR1,MTHFD2,GTF2A1,TRAP1,GPN1,SQLE,SENP3,KIAA0196,HS2ST1,DDX18,RIBC2,URB2,ACTR3,KLHL18,ISG20L2,POP5,NDUFB3,NOP56,CD96,ASNS,BCAS2,MRPS27,SSBP1,SAP30,RFC4,PMS1,RFC3,GARS,PDK1,MTIF2,NPM3,PCMT1,PNN,MAT2A,HTR7,TAF2,PES1,BAZ1A,CDC16,SMARCC1,ASTN2,H2AFX,FTSJ1,ALKBH1,RPS6KB1,MDN1,NOLC1,BAG1,RAB30,BRAF,XPC,TCF3,NFX1,SF3A3,LIAS,RNASEH2B,MBNL1,POM121,POLR3D,SNW1,NOP16,TRIAP1,PMPCA,UPF2,LARP4B,HNRNPM,ERICH1,APEX1,LDHA,ADSL,BMS1,UBE2K,DDX49,RPA1,OXSR1,RARS,TOE1,POLE2,ORC5,ATM,IGBP1,ADK,RABEP1,SRM,MVK,CSNK2A1,TTI1,GIT2,SMARCB1,ZNF804A,SRSF2,XRCC2,ANAPC10,UBAP2L,RELB,KIAA0922,B3GNTL1,RAN,POLE3,YARS,OGG1,TRIP13,TRIM14,CARM1,TMPO,ATF4,RBCK1,ZNF195,SKIV2L2,CDK4,PSMG1,ATG12,PITPNB,BRCA1,ODC1,DLST,CHAF1A,MLLT10,ARPC3,TIMM44,UBTF,HPRT1,INSIG1,E2F4,CRCP,PPP3CC,PRPF4,AK2,MCM6,PAX2,ALG8,SMG7,RNFT2,SUB1,MBD2,PPIL2,BUD31,SEMA3D,CTR9,GTF2H1,TIMELESS,KRT20,TRA2A,ZBED4,PSMA1,CYB5B,UBE2E1,MGAT2,PWP1,SYNCRIP,FDPS,HK2,TBPL1,SLC16A1,PTP4A2,DDX10,ZBTB24,RNF114,SMARCA4,RSL1D1,SSBP2,PIBF1,PELP1,CAD,FARSA,RRN3,MPHOSPH10,IDI1,NUP133,RNF2,ETF1,CORO1A,PRMT3,HTRA2,PRPF19,PARP2,R3HDM1,TMEM123,DKC1,NUP214,EIF3H,WARS,EXO1,RBBP8,ADNP,HNRNPR,COPS5,TIMM17A,CEBPZ,INTS9,ARC,MED20,DNAJC2,DBF4,VARS,SFI1,HDDC2,PTPN2,GART,SHMT2,FBL,SNAPC5,RPS6KB2,TOP1,PSMC3IP,ABCF2,SULT4A1,MARS,MEN1,EXOG,EIF5B,PIK3CB,TARS,POLR3G,ZNF330,CUL2,TAF4,SET,EIF2S1,NCBP2,TAF12,POLR1C,GCSH |
| 3.608e-12 | -26.35 | tRNA metabolic process | biological process | GO:0006399 | 193 | 62 | 16441 | 2138 |
CARS,CTU2,SARS,LARS2,RARS2,AARS2,LAGE3,HSD17B10,FARS2,VARS,POP5,NUP43,NUP160,AARS,YARS2,POM121,RPP30,FARSA,PUS3,GATC,DUS4L,NUP133,TRMT13,TRMU,ALKBH8,HARS2,RAN,FBL,TRMT10A,YARS,TRMT12,PPA1,SEH1L,NARS2,METTL1,EXOSC2,WARS2,GARS,NARS,HARS,ELP3,TYW1,METTL2A,MARS,NUP214,PUSL1,TARS,WARS,POP1,RANBP2,RARS,EPRS,DUS3L,TRMT5,ZBTB8OS,ADAT2,FTSJ1,CDKAL1,DTD1,PUS1,TSEN2,METTL2B |
| 4.668e-12 | -26.09 | protein binding | molecular function | GO:0005515 | 10510 | 1520 | 16491 | 2164 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,DCP1B,MRPL10,NAT10,MKS1,SBF2,CCNL2,HMOX2,LPAR3,CIAPIN1,SKI,ZFHX3,AP1M1,MAD1L1,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,RNMT,KLHL23,LIMA1,EHMT1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,AHNAK,RBSN,SSU72,RAD18,SYNGR2,DIRAS1,RUNX1,TPM1,BANP,EPM2AIP1,FAM189B,TRIO,PIK3R4,PARN,CDC73,PITPNM1,CHN1,CNST,UBE3A,APLF,MED24,TNPO3,GEMIN4,CCDC88C,PABPC1,SAMD3,ANGPT2,MYB,NOM1,LRRC20,KLRD1,ZNF675,GATAD2B,WDR61,STAG1,KCNQ3,ZNF587,ARID5B,USP10,SNAP25,TRIM37,SRA1,USP46,IRS1,DYNC1H1,KPNA1,GSTO2,NME7,RPL28,EHMT2,TRAP1,FGFBP1,CCDC85B,KIAA0196,PDLIM5,ARHGAP10,SRP14,SGSM3,GALE,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,LCLAT1,ZMAT2,UBL5,RPGRIP1L,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,TRMT12,ZC3H3,DENND1A,LYST,KMT2D,LRRC75A-AS1,EIF3J,CCNDBP1,KCNH3,MEF2D,GSTCD,DSP,VPS53,MAT2A,FBXL5,ARHGAP21,ELP2,MISP,NSMCE2,ARL13B,HOXA3,RPS6KB1,CEP170,BAG1,MAPT,COMMD10,HMGA2,SHQ1,GAS6,IP6K2,TRIM22,PSMF1,SNW1,TAF3,UNC13A,ANXA5,LTN1,FBXL19,ACTR3B,SAMD4A,PNMA1,SPTAN1,VPS37A,ZC4H2,ZC3H18,USP42,LDHA,CCDC113,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,ACOX1,AEN,BMP4,UQCC1,GPATCH11,GPATCH4,CUL7,TRIM16,AAMDC,SCAF8,HNRNPLL,MAP2K3,ECM1,SRSF2,COPS4,NCKIPSD,ZNF3,ZMYM2,SLC25A23,FAM184A,DBN1,DSC3,FMNL3,RBCK1,AEBP2,ATF4,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,LAMA2,KCNH2,ODC1,DLST,CXADR,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,UQCC2,USP15,CTU2,FOXO1,CLK1,PRSS3,NKD2,MAPK8IP3,FAN1,LAMTOR3,SMAD7,LYRM2,ARID1B,SPIRE1,SUB1,MLX,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,WNT16,LRSAM1,NIPSNAP1,USP49,IFT43,SETD2,OBSCN,MAPK1IP1L,TCF7L2,TBC1D2,SIL1,GGT7,SLC52A2,SH3PXD2A,BCCIP,USP7,SART1,ID1,OLFM2,SUCLG1,PAPD4,ARID2,SLC48A1,NTSR1,SLC2A1,LAGE3,RIPK1,TNKS1BP1,RADIL,PAG1,PPP1R9A,SEMA6A,PLXNB1,NRF1,JAG1,NUP133,GRIN2C,MYH15,AHCYL1,SPIDR,IPO11,PRPF19,ARHGAP17,AKAP8L,SSFA2,KIRREL2,RAB7A,VIM,EIF3H,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,HSPB8,MED20,EIF2B3,MUTYH,PARD3,FAM214A,NIFK,MINK1,KIZ,MCM10,HM13,RFX1,AGO2,VARS,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,TTC1,CPNE7,POLR1B,SNAPC5,PCSK6,FOXN3,SMARCAD1,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,PALLD,C8orf33,DKK1,CDH24,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,CUL4A,PRKCSH,GYG1,PRKCA,LRP5L,GABPB2,EXOC1,S100A10,ZFYVE28,CHD2,CSGALNACT2,ZNF646,FAM127A,OSBP2,VSNL1,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,SON,DDX60,CLNS1A,OSBPL1A,SPOP,DOT1L,GNAI1,DDAH2,TRRAP,CCNT1,SH3RF1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,BLMH,BMI1,ZMAT3,NMD3,CADM4,C9orf78,CDC42EP2,JUP,PRPF31,ST6GAL1,DLGAP4,DPM3,CRACR2A,C1orf50,PDCD5,NDUFS7,FAM192A,HR,SLC7A11,USPL1,SCAF1,MYC,MFAP2,PLEKHA2,CNOT4,CAV2,EXOSC2,KIAA1143,PCCA,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,NELFA,MTR,ANGPTL4,PHF6,SEC31A,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,MED15,DPEP1,C7orf50,NCOR1,SMYD3,CPT1C,SYT17,BIRC6,UROD,POP5,PTPRG,CORO6,HNRNPA3,FLNB,RING1,IGSF1,NOP56,BLOC1S2,SLX4,ASNS,PPID,SOCS6,MRPS27,DTNBP1,TTC3,RMDN3,ARL14EP,CDK12,CASP8AP2,SAP30,BRD4,PREX1,PCMT1,LRRC8A,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,G6PD,TRAF3,TBXA2R,SETD6,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,SFR1,ATXN7L1,ABL1,NEBL,ELP5,SDCBP2,CELF1,S100A14,ERRFI1,CLK2,SLC40A1,PXN,APEX1,ZFYVE1,AGPAT4,TMEM126B,PACS1,KLF6,INF2,IREB2,ZNF155,COQ9,ORC5,SVIL,ATM,APAF1,DDIT3,IPO4,KAT6A,LETM1,EIF3C,KMT2E,ATRX,PPIL1,DST,KANSL1,ANAPC11,SLC39A7,MYH3,ZEB1,YARS,CARM1,SRPK2,DEAF1,DTNB,TNK2,SESN2,SKAP2,SIRT6,ARRDC3,MTHFD1L,COTL1,KMT2C,ARPC3,TIMM44,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,MTCH1,FBXO45,DCTN3,ZCCHC8,VTA1,STXBP6,UBXN1,SMG7,EVPL,TIMM10,NAMPT,ELL,P3H1,WDR27,TENM3,ZCCHC7,PRF1,ATP6V0D1,AKAP11,HSD17B14,MSI2,ELOVL6,XPO5,ELP3,JMJD1C,ZBED4,LIG4,EIF2A,SYT1,HERPUD1,UBE2E1,POP1,APBB3,BICD1,FSCN1,FAT1,SLC16A1,CDKAL1,TBL1X,PFDN2,FNBP1L,PDE9A,AGO3,N4BP2L2,NR2C2AP,DMXL2,TCF12,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,CEMIP,TMEM183A,TNXB,SMARCA4,PBX1,COBLL1,TBCCD1,PIBF1,SBDS,ZC3H13,RAET1E,RRN3,MPHOSPH10,SOCS1,NVL,CBR4,SNTG2,FHIT,ITGAX,VCL,TMEM120B,UTP4,GNG5,AUP1,NPW,PRAME,ANTXR2,GRHL3,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,S100A16,BATF3,ALAD,KPNA3,IKZF4,HNRNPR,ARNTL,DUSP19,FKBP5,NFRKB,BRD9,SMG1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,MED18,ATF7IP,IGF2BP2,SEMA3E,ENOX1,BMP6,GFM2,MFHAS1,PEX7,SEC24C,DCTN4,STC2,FBL,PKNOX1,MICAL3,TOP1,KDM6B,ARNTL2,PPP1R9B,DNMBP,KDM5B,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,SULT4A1,ASAP3,SCMH1,PDE2A,PEAK1,EIF5B,NAALADL2,CTIF,SERINC1,GADD45A,AGTPBP1,VPS37B,POLR1C,NFKBIB,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,NOS1AP,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,RASSF3,RABGAP1L,PDS5B,WIZ,FNIP2,ZNF148,HRG,FXN,AVEN,CDK6,PTPRM,WLS,GNL3,PACRGL,MSRB3,AKAP12,MCL1,DCUN1D5,TMSB4X,STOML2,DDX3X,ZNF266,SUPT4H1,BRCA2,TMEM139,FIS1,FIP1L1,LPP,MEF2C,CARS,TNNC1,HERC2,EP400,CLDN15,TRIP6,KHDRBS1,SLK,SIRT7,RSF1,CLINT1,SLC1A1,YARS2,SH2B3,EIF2S2,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,ANP32B,PRMT5,MAP3K12,AGL,FMNL2,TOMM34,SERBP1,HMGCR,PEA15,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,CPT1A,ABCF1,ZNF655,NCDN,ZNF783,GTF2A1,LEMD3,CDK9,SURF1,GPN1,ADGRE5,SENP3,CNOT6,MB21D2,COG5,SPRED2,FAM208B,DNM3,ZNF516,MAP2K5,TRERF1,DDX18,BTBD2,NPAS2,ACTR3,MYH9,SAFB2,STAM,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,FMNL1,PYCRL,ATRIP,GSTA4,CEP63,LSM10,MALL,GARS,KRT7,FAM111B,STAMBP,NPM3,ASUN,LGALS1,DRICH1,ARHGEF10,ATP6V0A1,FKBP3,FGFR1,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PAM,FUS,BRCC3,YEATS2,ANKS1A,LAMA5,LRCH1,TRIM36,NOL4L,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,TADA3,NPRL2,SUV39H2,GATC,TMSB10,PVRL3,ARHGAP1,SOX6,HNRNPM,DIS3L2,ULBP1,NUDC,FAM98A,FGF9,FBXO17,CEP83,FRA10AC1,R3HDM2,IL6R,FAM126B,UBE2K,PDE3B,FOXC1,KISS1R,RPA1,TRIB3,TOE1,RARS,BAZ2B,PXDN,POLE2,STX1A,ARID3B,PTPN4,PSAP,IGBP1,NUDT22,ANAPC4,KDM4C,CORO2B,SRM,PPARGC1B,TFIP11,POLR1A,MFGE8,HECTD3,NREP,CSNK2A1,RNF43,TTI1,SEC16A,GIT2,BIRC2,ABL2,PHKA1,DHX33,MARVELD2,XRCC2,PPCDC,UBAP2L,ZNF85,POLE3,RAN,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,FLNC,METTL1,CHD9,SLC3A2,ZNF124,SKIV2L2,ZNF414,BAZ2A,KATNAL1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,TOM1L2,TP53BP1,FAM206A,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,CHMP4C,AOC3,TTN,MCM6,STX8,HSD17B10,HES6,ZFP36L1,TRIM15,RLF,RNF40,KIAA1958,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NAA38,CAMKK2,CRADD,PAXBP1,TLE3,HOMER2,BCS1L,WDR25,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,ATXN7,ITPRIPL1,SPAG9,PALB2,SYNCRIP,SNAP23,IRAK2,TBPL1,PPP1R12B,BRSK2,NAPA,PRKAR2A,TESC,CYLD,FAM207A,RBFOX2,GPR143,PPP2R2A,ZNF83,RNF24,RPAIN,PELP1,KDM1A,DENR,CAD,ZBTB21,DNAJB6,IKBKB,HIRIP3,RNF2,ETF1,CORO1A,PRMT3,CASP10,CTC1,SEC24A,KAT8,PCGF3,EVL,TUBA1A,DDX41,C1QTNF1,CPOX,MANBAL,TMEM123,AKAP13,ENC1,NUP214,BTBD11,SMAD3,RANBP2,SLC30A3,RBBP8,SIX5,ITGA2,ZNF436,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,UNC13D,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,C15orf57,IQGAP2,PTPN2,SACS,ANXA7,HIST2H3D,DDX31,FBXO31,CD44,PCK2,HSD17B12,ADAMTSL3,ZMYM5,TPM4,TEX14,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,PIK3CB,CHCHD6,ZRANB3,CENPP,MKX,TPD52L2,GPC2,ADAT2,SET,MSH3,GLG1,EIF2S1,RWDD2B,ITGB4,RPS6KC1,MIPOL1,CGN,POLB,MYCBP2,PRDX6,PRKAB2,TNFRSF21,DDX19A,PLRG1,ENAH,IKBIP,RAC3,UBR5,MGA,RPS16,PAK1IP1,RNF111,VPS52,CEP135,PRADC1,FUT11,DDN,SNU13,SETD1B,ATG9A,NR6A1,NOL8,EYA3,TCEB3,CUX1,DESI1,HSH2D,SEMA3F,SAP30BP,SH3GL1,SKIL,SEMA3C,CCNB1IP1,TXN2,FAM118A,SYNPO,PTPN14,EFNB2,IFT57,DROSHA,EGR1,CELSR1,ZHX3,CCDC53,ANKRD17,AK6,OPHN1,PID1,CCDC47,TGFBR2,CHD5,CD226,ANXA10,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ENTPD5,TSPAN2,ASAP1,COPS3,ATIC,SLC16A9,GTF3C3,IGF2BP1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,PLCB1,ARIH2,ZNF425,EPRS,KIDINS220,NSF,UBAP1,PMEPA1,RIOK3,PURB,PEX13,MACROD1,MAP2K4,TBKBP1,AMOTL1,LIN28B,RWDD1,RIBC2,SPRYD7,OLA1,KLHL18,FOSL2,AP1B1,PAIP2,TERF2IP,PHC2,FLAD1,CHD7,SHC1,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,NAA35,RFC4,RFC3,MPP6,CFAP221,PDK1,DLG4,MED16,POLG2,TBC1D16,STK10,DHX57,DCBLD2,VDR,YIPF2,DNAJA3,H2AFX,ACP1,KLHDC4,MDN1,ANXA2,PDCD11,NOLC1,NCOR2,SCAMP3,UTP14A,C10orf2,MRI1,TCF3,RTN4,MLH1,CEP126,MON2,NOL3,IKBKAP,GDPD5,REEP5,FOXO3,MAD2L2,TMCO6,NEDD4,DCTPP1,ZNF239,RGS17,COMMD9,PTRF,LRP2BP,NISCH,TRIAP1,PHYKPL,HARS2,RDX,COPS7B,UPF2,NLGN3,EXOSC4,YBX3,MAP3K14,LARP4B,PLEKHG4,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,APTX,PTK2,OASL,NOP58,POLR2A,ECH1,YIF1A,KLHL22,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,RABEP1,BORCS5,LRRC41,STK4,MVK,FEM1C,UBN1,NF1,PTPRA,KIF5A,FANCD2,TRPM6,RCHY1,PLOD1,BCOR,SIRT2,CUTC,AHCYL2,EDC3,WNT2B,SMARCB1,RTN1,RAP1A,YLPM1,THADA,ATG3,ZNHIT6,RELB,HYAL1,IPP,JOSD1,PCOLCE2,SLC27A5,CCDC121,OGG1,LONP1,TRIP13,PRKACB,TIMM50,LAMA4,ZBTB17,GPM6A,TRIM13,TXLNG,SLC38A1,CMIP,PCED1B,HDAC8,CAV1,SOX4,SERGEF,CHAF1A,TAF9B,GEMIN5,RHOU,UBTF,PAF1,EPN2,SUFU,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,ZNF397,COPS6,EMSY,TNRC6A,SLC12A7,VIPR1,RELL2,FN1,TAF1,SEC24D,PAX2,DPF2,CDIP1,C11orf54,XPO7,CMTM3,RHBDD1,DDIT4,TOX4,CEP164,ATXN2,BANF1,BUD31,CCDC112,SEMA3D,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,RANBP6,KRT20,PDE4A,PSMA1,WWC1,PRDM1,C11orf65,BLOC1S4,ISG15,MYBBP1A,INTS5,SDCCAG8,HK2,EXOC4,RRAGA,PTRH2,KIAA1328,TMEM182,PDSS2,ZBTB24,EXOC3-AS1,PCNT,MMRN2,CELSR3,MYO7A,CSTA,GBF1,SLC39A1,MIEF1,VPS18,FARSA,BRE,CCDC50,CAMTA2,SLC38A2,CPSF3,MET,ZNF460,TSPAN14,TMEM14C,HTRA2,MCEE,PHLDB2,COL5A2,TFCP2,PARP2,SFSWAP,TOR1AIP2,C1orf174,RAB10,WARS,ZC3H12A,HYAL3,ADNP,COPS5,HEATR1,DISP1,SCARB1,USP11,TSPAN5,TNIK,DNAJA4,SH2D3A,SULT1C2,H2AFJ,TKFC,LETMD1,PPHLN1,SFI1,HDDC2,PRKCH,IL17RE,CTNNBL1,TANK,DSG2,SHMT2,TTC17,UTS2,AMOT,DMRT1,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,ARHGAP32,LENG8,MEN1,SYMPK,TARS,HSPA1B,MFN2,RERE,MPP7,CUL2,NCBP2,ZRANB2,TATDN1,ZAK,ARHGAP27 |
| 5.034e-12 | -26.01 | HAMAI_APOPTOSIS_VIA_TRAIL_UP | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_UP | 554 | 129 | 17758 | 2279 |
MYCBP2,PHF3,ZNF107,ENAH,CSPP1,HLTF,ZNF44,BIRC2,EXOC1,NSRP1,ATG3,PDS5B,ZNF148,ZNF85,CSGALNACT2,SKAP2,ZNF195,RNMT,SKIV2L2,LIMA1,KIF15,WDHD1,BRCA1,SON,OSBPL1A,RAD18,DNAJC1,LUC7L3,LRRC40,DPP4,ADAM9,SEMA3C,ZNF397,PRPF38B,ITFG1,SLK,CCDC47,RSF1,PRPF39,PHGDH,RLF,FKBP1A,UBE3A,EIF2S2,CEP290,ABCA5,WDR60,NOC3L,NRIP1,AKAP11,SCAF11,MYO10,RB1CC1,PCCA,HAUS6,LIG4,EIF2A,SNAP25,MTR,VPS13C,EPRS,KIDINS220,ZCCHC6,ZNF430,KIAA0196,DDX10,ARHGAP10,BCCIP,FAM208B,RWDD1,PIBF1,EEA1,RIOK2,JAG1,IDI1,MPHOSPH10,BCAS2,UCHL5,SLC38A2,BCAP29,NT5C,CEP63,MGLL,CASP8AP2,NARS,EIF3J,PNN,RAD54B,BAZ1A,IFT81,RBBP8,HIPK2,CEBPZ,BRCC3,XRCC4,ZBTB11,CEP170,MID1,PKIB,DNAJA4,SULT1C2,DBF4,ATF7IP,OPA1,RMI1,IQGAP2,TTC1,SACS,CWC27,RDX,ACTR3B,C12orf4,POLK,SMARCAD1,ZNF654,PALLD,PPIP5K2,ZNF407,EIF5B,ZDHHC11,BAZ2B,AGTPBP1,CUL2,MSH3,ATM,RBM26,TATDN1,RPS6KC1,RABEP1 |
| 5.567e-12 | -25.91 | urinary_tract-bladder-carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma | 14745 | 2000 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,LIMA1,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,DIRAS1,RIOK1,RUNX1,TPM1,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,MAB21L3,DDR2,CD99L2,FAM122B,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,MCM9,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,PI4KAP2,EIF3J,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,KCNH3,SLC35D1,NUDT15,DSP,VPS53,MAT2A,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,RAB30,MORC2,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,C15orf41,SAMD4A,PNMA1,RPL22L1,SPTAN1,TTPAL,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,METTL8,TRIML2,ZMYM2,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,PSMG1,MARCKSL1,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,SNX24,CASS4,SIL1,PTP4A2,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,TLCD1,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,EIF3H,ZNF251,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,TMEM161A,POLR1B,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,FAM127A,OSBP2,VSNL1,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,DENND4A,SON,DDX60,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,CDC42EP2,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,SSR4,PDCD5,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ZNF850,PHF6,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,KIAA0232,TMEM104,POP5,PTPRG,CORO6,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,LRRC8A,GNL1,SATB2,MARCH6,ERC1,HSD3B7,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,TRAF3,SETD6,XRCC4,MID1,SSH2,NOSTRIN,BRAF,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,PHLDA2,ABL1,NEBL,SDCBP2,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,KLF6,GUF1,SLC23A2,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,ZNF354A,WDR27,ISPD,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,CHMP2A,SNX27,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,PRAME,METTL2A,GRHL3,ATXN1,POU2F1,METTL15,DKC1,EDEM2,UBR4,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,WDR26,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NFKBIB,NIT1,GNB3,ASCC1,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RASSF3,FAAH2,RABGAP1L,PDS5B,WIZ,ZNF148,HRG,FXN,AVEN,CDK6,PTPRM,WLS,GNL3,PACRGL,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,ZNF266,TMEM139,FIP1L1,RBP1,LPP,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,PEA15,TIMM8B,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,FMNL1,ATRIP,NT5C,GSTA4,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,NPM3,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,HLA-DMA,TAF2,GNG2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,JMJD6,AKT1S1,TGFB2,BHLHE40,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,IL6R,ZNF467,PDE3B,DDX49,FOXC1,CASC1,RPA1,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,BCAS4,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,ZNF124,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,ZNF91,CCDC28B,PEX1,KIF16B,GLS,ZNF622,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,NOMO3,SARS,AOC3,PGPEP1,MCM6,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,TRIM15,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,LPCAT2,RBFOX2,GPR143,RSL1D1,PPP2R2A,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,CYB5D1,HIRIP3,ZFP37,ETF1,RNF2,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,C1QTNF1,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,ZNF436,PRRT3,ZNF18,NFASC,PUS1,SEPT5,ZNF589,PPIL3,AP2S1,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,C14orf159,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,CWC27,HIST2H3D,PRICKLE2,GREB1,DDX31,CD44,PCK2,FBXO31,FAM71E1,ADAMTSL3,GINS3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,RAP1GDS1,C11orf49,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,MKX,POLR3G,ZRANB3,TPD52L2,TMEM237,GPC2,SRBD1,ZBTB8OS,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RPS16,RNF111,VPS52,PAK1IP1,ME1,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,CCDC47,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ASAP1,COPS3,ATIC,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMA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|
| 9.154e-12 | -25.42 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 16661 | 2203 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RASSF3,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.000e-11 | -25.33 | bladder | COSMIC cancer mutations | bladder | 14810 | 2006 | 17775 | 2278 |
PTP4A1,ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,ATP5G2,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,LIMA1,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,RIOK1,DIRAS1,RUNX1,TPM1,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,CNST,UBE3A,DHX37,APLF,WDR60,MED24,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,ALG6,STAG1,KCNQ3,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,MAB21L3,DDR2,CD99L2,ISG20L2,GRINA,FAM122B,NUP43,ST3GAL6,LCLAT1,MCM9,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,PI4KAP2,EIF3J,SLCO6A1,PCNXL2,CCNDBP1,KCNH3,MEF2D,SLC35D1,NUDT15,DSP,VPS53,MAT2A,FBXL5,ARHGAP21,KDM4B,ELP2,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CATSPERG,METTL2B,CEP170,RAB30,BAG1,MAPT,MORC2,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,PTGS1,ZNF710,FBXL19,C15orf41,SAMD4A,RPL22L1,PNMA1,SPTAN1,TTPAL,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,METTL8,TRIML2,ZMYM2,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,PSMG1,MARCKSL1,SUMO3,LAMA2,KRTCAP2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,BSN,DYRK1B,LSS,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PRPF4,PPP3CC,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,MAPK8IP3,FAN1,SMAD7,LAMTOR3,ZIC2,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,CCDC167,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,IFT43,USP49,HAUS6,SETD2,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,SNX24,CASS4,SIL1,GGT7,PTP4A2,DDX10,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,OLFM2,UPK3B,SUCLG1,PAPD4,ARID2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PAG1,PPP1R9A,DDX60L,SEMA6A,ZNF121,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,TLCD1,KDM3B,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,MCM10,AUH,HM13,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,TMEM161A,POLR1B,C12orf4,AP4S1,LRRIQ1,MON1A,SMARCAD1,FOXN3,ABCF2,KRTCAP3,PLAC8L1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,C8orf33,POLR3A,SMPDL3B,DKK1,CDH24,CACNB1,NOL10,SAMD5,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,FAM127A,OSBP2,VSNL1,CAMSAP2,EFHC1,HIST1H2BL,ZDHHC14,DENND4A,SON,DDX60,TMEM206,PLCXD2,SPOP,OSBPL1A,DOT1L,GZF1,GNAI1,DDAH2,TRRAP,CCNT1,SH3RF1,LSM14A,HSPBAP1,NSMCE1,ARL6IP5,HIC2,XPNPEP1,WDR66,NRP1,TNFRSF10D,BMI1,BLMH,SPOCK2,RFXAP,ZMAT3,SPOCK3,NMD3,CADM4,PRPF38B,C9orf78,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,DLGAP4,TATDN3,CENPB,DPM3,SSR4,PDCD5,NDUFS7,MTUS1,TECTA,FAM192A,HR,SLC7A11,LDOC1L,NOVA2,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,EXOSC2,IFNGR2,ANAPC13,PRIM2,RREB1,PCCA,RDH10,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,SLC26A11,MTR,ZNF850,ANGPTL4,PHF6,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,KIAA0232,UROD,TMEM104,POP5,PTPRG,CORO6,HNRNPA3,RING1,FLNB,IGSF1,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,LRRC8A,GNL1,SATB2,MARCH6,ERC1,HSD3B7,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,MID1,SSH2,NOSTRIN,BRAF,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,PHLDA2,FAM8A1,ABL1,NEBL,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,MS4A15,CLK2,NAV3,FER1L5,TMC7,SLC40A1,PXN,TTLL5,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,GUF1,KLF6,SLC23A2,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,SVIL,ATM,APAF1,ADK,DDIT3,IPO4,IMMP2L,ZNF76,PIGM,LETM1,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,SESN2,FBXW4,ZNF195,SKAP2,SIRT6,ITPA,ARRDC3,VWCE,MINA,TMEM216,KSR2,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,TIMM44,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,FBXO45,ZCCHC8,RHOBTB1,VTA1,STXBP6,PCSK7,SMG7,EVPL,QSER1,NAMPT,RNF141,ELL,ZNF354A,WDR27,ISPD,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,MTHFD1,HSD17B14,ZNF629,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZBED4,ZFP14,LIG4,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,APBB3,SYCP2L,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,SLC16A1,CDKAL1,TBL1X,PFDN2,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,CBR4,PPFIBP1,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,PRAME,METTL2A,GRHL3,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,RNF130,ARC,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,MFHAS1,FAM49A,GFM2,PEX7,SCN1B,SEC24C,DCTN4,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,SULT4A1,METTL23,SCFD2,ASAP3,ZNF324B,SCMH1,PDE2A,TMEM187,EIF5B,NAALADL2,CTIF,ZNF221,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NFKBIB,NIT1,ASCC1,GNB3,CACNA1H,CSPP1,CHAC1,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,TOM1L1,NEK6,SREBF2,NSRP1,PMAIP1,SYN2,RASSF3,FAAH2,RABGAP1L,PDS5B,WIZ,ZNF148,HRG,FXN,AVEN,CDK6,PTPRM,WLS,GNL3,PACRGL,RFX2,MSRB3,AKAP12,MCL1,PLEKHM3,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,TMEM139,FIP1L1,RBP1,MEF2C,LPP,CARS,HERC2,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ANP32B,NOC3L,CALN1,PRMT5,ZNF518B,MAP3K12,AGL,COQ3,FMNL2,TOMM34,SERBP1,HMGCR,FADS1,PEA15,GTF2H3,TIMM8B,BDNF,COL17A1,MYO10,RB1CC1,PRDM16,STPG1,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,MBNL2,CPT1A,ONECUT2,ABCF1,ZNF655,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,DNM3,ABCA3,ZNF516,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,FMNL1,ATRIP,GSTA4,NT5C,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,FAM111B,STAMBP,NPM3,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PES1,GNG2,TAF2,HLA-DMA,CDC16,IQCH,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,YEATS2,LAMA5,LRCH1,TRIM36,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,SOX6,HNRNPM,LYPLA2,DIS3L2,ULBP1,NUDC,DDHD1,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,POLK,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,IL6R,ZNF467,PDE3B,CASC1,DDX49,FOXC1,RPA1,TRIB3,TOE1,ETFDH,RARS,BAZ2B,PXDN,POLE2,ARID3B,STX1A,SLC25A19,PTPN4,SLCO5A1,PSAP,GPAM,IGBP1,DOCK6,NUDT22,ANAPC4,CORO2B,KDM4C,SRM,BCAS4,PPARGC1B,TFIP11,POLR1A,MFGE8,HECTD3,CSNK2A1,RNF43,TMEM132A,TTI1,COX10,SEC16A,BIRC2,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,TMPO,SF3A1,PTPRK,CDC37,FLNC,METTL1,CHD9,GCNT2,ZNF124,ABCC4,SKIV2L2,HARS,ZNF414,BAZ2A,KATNAL1,GDPD1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,ZNF91,CCDC28B,KIF16B,PEX1,GLS,ZNF622,TOM1L2,TP53BP1,PER1,EEFSEC,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,NOMO3,SARS,AOC3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,RNF40,DOPEY1,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,RNH1,MEX3B,ZNFX1,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SNAP23,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,RBFOX2,LPCAT2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,PELP1,RPAIN,KDM1A,DENR,METTL16,CAD,UBR1,DNAJB6,FSIP2,ARMC5,IKBKB,CYB5D1,ZDHHC6,HIRIP3,ANO8,RNF2,ETF1,ZFP37,CORO1A,AKNAD1,PRMT3,CASP10,CTC1,TMEM200A,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,C1QTNF1,MANBAL,SLC35F2,TMEM123,AKAP13,ENC1,ARL5B,NUP214,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,ZNF333,TIMM17A,ABHD3,ITGA2,ZNF436,PRRT3,PUS1,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,ZNF589,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,SACS,NDUFV1,ZNF561,CWC27,PRICKLE2,HIST2H3D,GREB1,DDX31,FBXO31,CD44,PCK2,FAM71E1,GINS3,ADAMTSL3,ZNF654,ZMYM5,TPM4,DHX34,TEX14,RAP1GDS1,C11orf49,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,ARMC3,ZRANB3,MKX,POLR3G,TPD52L2,TMEM237,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,ADAMTS6,IKBIP,RAC3,AARS,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,VPS52,ME1,CEP135,MEIS3,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,EYA3,GNG7,TCEB3,CUX1,SEMA3F,FOXRED1,MAK16,SAP30BP,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,DNAH2,GREB1L,SEMA3C,CCNB1IP1,TXN2,FAM118A,SYNPO,ZNF598,PTPN14,EFNB2,WDR75,IFT57,DROSHA,EGR1,CELSR1,CCDC53,ANKRD17,ZHX3,OPHN1,GTF2IRD1,CCDC47,TGFBR2,CHD5,CD226,ANXA10,IGF2BP3,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ASAP1,COPS3,ATIC,GTF3C3,SAMD13,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,NSF,UBAP1,PMEPA1,ZZEF1,D2HGDH,ZBTB12,RIOK3,PURB,UMPS,IQSEC2,MACROD1,MAP2K4,RTTN,PPDPF,PTCD2,TBKBP1,AMOTL1,TRPM2,RWDD1,SPATA2L,ZBTB37,RIBC2,URB2,HFM1,NDUFB5,C1QTNF7,OLA1,KLHL18,SPATS2L,FOSL2,TM4SF19,SLC25A44,AP1B1,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,TMEM184A,PUS3,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SERPINH1,PNPLA4,KMT2A,PLEKHA4,NAA35,ATP6AP1L,RFC4,ZCCHC14,MPP6,RFC3,PDK1,MTIF2,SFXN4,WDPCP,DLG4,KIAA1586,GALK2,MED16,PNN,POLG2,TBC1D16,STK10,DHX57,DCBLD2,CPED1,VDR,HTR7,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,KLHDC4,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,TTC27,CA11,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,MON2,IKBKAP,NOL3,GDPD5,REEP5,FOXO3,MAD2L2,TMCO6,NEDD4,DCTPP1,ZNF239,ZNF483,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,UPF2,RDX,COPS7B,NLGN3,EXOSC4,LARP4B,PLEKHG4,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,TBRG4,APTX,OASL,NOP58,YIF1A,FBXO21,KLHL22,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,LRRC41,SLC43A1,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,RCHY1,PLOD1,ZNF107,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,WNT2B,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,NDUFA6,SLC27A5,CCDC121,OGG1,LONP1,TRIM14,PRKACB,TIMM50,LAMA4,ZBTB17,TRIM13,GPM6A,TXLNG,CMIP,SLC38A1,ZNF680,GPCPD1,HDAC8,CAV1,SOX4,TCTN1,SERGEF,CHAF1A,CDHR3,TAF9B,PAF1,TMEM132B,GEMIN5,RHOU,UBTF,EPN2,SUFU,GATA6,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,XPO7,PHGDH,RHBDD1,ETFB,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,GLTP,NRIP1,N4BP2,POLR1E,CPSF3L,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,TMEM241,ANKRD20A4,DNAH14,UBAP2,MYBBP1A,ATAD5,EP400NL,INTS5,SDCCAG8,RRAGA,HK2,EXOC4,PTRH2,KIAA1328,ZFP90,TMEM182,C12orf45,PDSS2,C7orf26,ZBTB24,ZNF706,ASH1L,PCNT,MMRN2,SLC5A5,CELSR3,MYO7A,ST7L,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,TSPAN14,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,ATP8B2,C1orf174,PUSL1,RAB10,WARS,RAD54B,TPK1,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,DISP1,HEATR1,USP11,ECHDC1,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SH2D3A,SULT1C2,C17orf80,NSUN6,H2AFJ,DBF4,CLSTN2,LETMD1,CCDC7,PPP1R1C,MFSD10,SFI1,HDDC2,MAN1A1,PRKCH,IL17RE,GART,CTNNBL1,HAS3,TANK,DSG2,KDELC1,CLDND1,TTC17,UTS2,AMOT,DMRT1,SLC25A1,MSX1,IL11RA,TEAD1,PPP1R21,ANKMY2,MARS,PHACTR2,ARHGAP32,LENG8,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,RERE,MFN2,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,ZRANB2,MBD6,TATDN1,PREPL,ZAK,MMP16,HRH1 |
| 1.000e-11 | -25.33 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14810 | 2006 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,LIMA1,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,DIRAS1,RIOK1,RUNX1,TPM1,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,MAB21L3,DDR2,CD99L2,FAM122B,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,MCM9,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,PI4KAP2,EIF3J,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,KCNH3,SLC35D1,NUDT15,DSP,VPS53,MAT2A,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,RAB30,MORC2,HMGA2,SHQ1,XRRA1,ATG2B,GAS6,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,C15orf41,SAMD4A,PNMA1,RPL22L1,SPTAN1,TTPAL,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,METTL8,TRIML2,ZMYM2,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,PSMG1,MARCKSL1,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,SNX24,CASS4,SIL1,PTP4A2,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,TLCD1,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,EIF3H,ZNF251,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,TMEM161A,POLR1B,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,FAM127A,OSBP2,VSNL1,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,DENND4A,SON,DDX60,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,CDC42EP2,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,SSR4,PDCD5,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ZNF850,PHF6,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,KIAA0232,TMEM104,POP5,PTPRG,CORO6,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PREX1,LRRC8A,GNL1,SATB2,MARCH6,ERC1,HSD3B7,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,MID1,SSH2,NOSTRIN,BRAF,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,PHLDA2,ABL1,NEBL,SDCBP2,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,KLF6,GUF1,SLC23A2,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,ZNF354A,WDR27,ISPD,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,CHMP2A,SNX27,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,PRAME,METTL2A,GRHL3,ATXN1,POU2F1,METTL15,DKC1,EDEM2,UBR4,ARMC4,ALAD,KPNA3,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,WDR26,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NFKBIB,NIT1,GNB3,ASCC1,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RASSF3,FAAH2,RABGAP1L,PDS5B,WIZ,ZNF148,HRG,FXN,AVEN,CDK6,PTPRM,WLS,GNL3,PACRGL,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,ZNF266,TMEM139,FIP1L1,RBP1,LPP,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,EIF2S2,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,PEA15,TIMM8B,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,FMNL1,ATRIP,NT5C,GSTA4,CEP63,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,NPM3,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,HLA-DMA,TAF2,GNG2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,JMJD6,AKT1S1,TGFB2,BHLHE40,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,IL6R,ZNF467,PDE3B,DDX49,FOXC1,CASC1,RPA1,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,POLE2,STX1A,ARID3B,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,BCAS4,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,ZNF124,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,ZNF91,CCDC28B,PEX1,KIF16B,GLS,ZNF622,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,NOMO3,SARS,AOC3,PGPEP1,MCM6,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,TRIM15,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,LPCAT2,RBFOX2,GPR143,RSL1D1,PPP2R2A,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,DENR,CAD,METTL16,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,CYB5D1,HIRIP3,ZFP37,ETF1,RNF2,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,C1QTNF1,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,ZNF436,PRRT3,ZNF18,NFASC,PUS1,SEPT5,ZNF589,PPIL3,AP2S1,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,C14orf159,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,CWC27,HIST2H3D,PRICKLE2,GREB1,DDX31,CD44,PCK2,FBXO31,FAM71E1,ADAMTSL3,GINS3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,RAP1GDS1,C11orf49,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,MKX,POLR3G,ZRANB3,TPD52L2,TMEM237,GPC2,SRBD1,ZBTB8OS,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RPS16,RNF111,VPS52,PAK1IP1,ME1,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,CCDC47,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ASAP1,COPS3,ATIC,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,TTYH2,PTPN12,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,NSF,ZZEF1,ZBTB12,D2HGDH,RIOK3,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,PPDPF,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,SPATA2L,ZBTB37,URB2,RIBC2,HFM1,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,HTR7,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,CA11,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,MAD2L2,NEDD4,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,UPF2,COPS7B,RDX,NLGN3,EXOSC4,LARP4B,PLEKHG4,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,TBRG4,APTX,OASL,NOP58,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,SLC43A1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,RCHY1,PLOD1,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,WNT2B,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,NDUFA6,CCDC121,OGG1,TRIM14,LONP1,PRKACB,TIMM50,LAMA4,ZBTB17,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,SOX4,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,XPO7,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,TMEM241,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,PTRH2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ZNF706,ASH1L,PCNT,MMRN2,CELSR3,SLC5A5,MYO7A,ST7L,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,ATP8B2,C1orf174,PUSL1,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,DISP1,HEATR1,USP11,ECHDC1,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,H2AFJ,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,MFSD10,HDDC2,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,CLDND1,TTC17,UTS2,AMOT,DMRT1,SLC25A1,MSX1,IL11RA,TEAD1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,NAPEPLD,TARS,RERE,MFN2,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,HRH1 |
| 1.145e-11 | -25.19 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3789 | 611 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,HLTF,NUP160,SYNJ1,NOS1AP,SKI,PCDH7,MMP7,NEK6,PMAIP1,RABGAP1L,RASSF3,MAD1L1,KDM5C,FXN,AVEN,CDK6,NRAS,PTPRM,AKAP12,MCL1,MCM2,ZNF197,DDX3X,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,KHDRBS1,SIRT7,TRIO,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,DHX37,MCM5,MED24,ANP32B,GEMIN4,MAP3K12,MYB,HMGCR,ZNF675,PEA15,GTF2H3,IFRD1,STAG1,PRDM16,EIF4A2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,IRS1,KPNA1,TRAP1,SURF1,GPN1,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,MYH9,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,MMP14,MSH4,TRMT12,PMS1,KMT2D,ARHGEF10,ATF7IP2,ADAM32,MEF2D,FKBP3,FGFR1,TAF2,GNG2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,HIPK2,RPS6KB1,FUS,BRCC3,BAG1,RAB30,TRIM36,HMGA2,XPC,SESTD1,ID2,AKT1S1,GAS6,IP6K2,POM121,TADA3,SNW1,SUV39H2,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,LDHA,IL6R,DDX49,FOXC1,ANXA1,RPA1,OXSR1,TRIB3,NSD1,POLE2,HERC1,PTPN4,AEN,BMP4,IGBP1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,PPARGC1B,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,DHX33,XRCC2,NCKIPSD,RAN,POLE3,ZMYM2,ETV1,PTPRK,VPS13B,FMNL3,CHD9,PPARG,CDK4,TSN,HSPA5,COL4A3BP,GMFB,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,ARL4A,E2F4,PER1,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,MEX3A,HES6,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,LAMC1,CRADD,SETD2,OBSCN,MEX3B,NR2F1,VAC14,SPAG9,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,USP7,SART1,ID1,PPP2R2A,RIPK1,RNF24,PPP1R9A,FDX1,PLXNB1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,CORO1A,IPO11,CASP10,KDM3B,SKIV2L,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,AUH,MAP3K13,APRT,FOXP1,CSNK1A1,PTPN2,ADH5,SACS,SURF2,DDX31,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,POLB,MYCBP2,CUL4A,PRDX6,PRKAB2,TNFRSF21,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,MGA,SUCLG2,CHD2,NR6A1,GNG7,ZDHHC14,DENND4A,PLCXD2,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,CCNT1,HSPBAP1,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,IFT57,DROSHA,JUP,EGR1,ANKRD17,ST6GAL1,CENPB,TGFBR2,PDCD5,CHD5,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,SAMD13,IGF2BP1,PRPS1,TERF2,SIK3,DDX28,PRIM2,ANAPC13,IFNGR2,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,CAT,HIF1A,PMEPA1,VCAN,SPEN,RIOK3,UMPS,NCOR1,DHCR7,MAP2K4,SMYD3,BIRC6,PTPRG,RING1,PHC2,NUBPL,TERF2IP,SHC1,KDM2A,PPID,UCHL5,LPIN2,SOCS6,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,RFC3,BRD4,PDK1,PREX1,MED16,POLG2,STK10,ERC1,DHX57,VDR,BAZ1A,CAMK2D,SMARCC1,DNAJA3,H2AFX,ALKBH1,TRAF3,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,TCF3,MLH1,NOL3,IKBKAP,DNAJC22,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,COPS7B,S100A14,CLK2,NAV3,PXN,APEX1,FZD3,ADSL,FBXO21,ORC5,RNF138,ATM,APAF1,ADK,RABEP1,IPO4,DDIT3,STK4,PIGM,PHF3,NF1,ATRX,PTPRA,FANCD2,TRPM6,RCHY1,SIRT2,BCOR,STK33,SMARCB1,MRPS30,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,ANAPC10,RELB,OGG1,PRKACB,TRIM14,SRPK2,TNK2,SESN2,TRIM13,FBXW4,SIRT6,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,SOX4,KMT2C,SERGEF,GEMIN5,RHOU,HLCS,DNAJC1,CSMD3,ASB3,EME1,COPS6,ZC3H8,MTCH1,FBXO45,PIGN,AK2,TAF1,RHOBTB1,MED13L,PCSK7,XPO7,DDIT4,RNF141,ELL,NRIP1,N4BP2,AKAP11,MSI2,KRT20,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,SYT1,UBE2E1,HK2,TBCK,FNBP1L,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,PBX1,DHX35,RIOK2,BRE,SOCS1,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,ITGAX,MET,GNG5,PARP2,METTL2A,DKC1,UBR4,RAB10,RAD54B,TPK1,IKZF4,KPNA3,COPS5,DUSP19,FKBP5,SCARB1,RNF130,USP11,SMG1,DNAJC2,BCKDK,TNIK,DNAJA4,SH2D3A,DYM,CAMK1,DBF4,MED18,ATF7IP,IGF2BP2,PPP1R1C,FAM49A,PIP4K2A,PRKCH,CTNNBL1,TANK,TOP1,RPS6KB2,KDM6B,DNMBP,IL11RA,GPHN,FGF2,KDM5A,MARS,ARHGAP32,NAPEPLD,GADD45A,CUL2,NFKBIB,ZAK,MMP16 |
| 1.155e-11 | -25.18 | cellular component organization or biogenesis | biological process | GO:0071840 | 5468 | 849 | 16441 | 2138 |
ARHGAP26,ACTG1,AARS2,MRPL10,MKS1,CACNA1H,TUBE1,SBF2,HLTF,COA1,NUP160,SYNJ1,LPAR3,CIAPIN1,AMBRA1,SKI,MMP7,NEK6,PMAIP1,AP1M1,MAD1L1,PDS5B,WIZ,KDM5C,FXN,FTSJ3,NRAS,LIMA1,PTPRM,GNL3,EHMT1,AP4B1,NFIA,KIF15,WDHD1,MCL1,MCM2,TMSB4X,STOML2,DDX3X,AHNAK,RBSN,BRCA2,SUPT4H1,MPV17,FIS1,TPM1,MEF2C,BANP,EP400,CLDN15,TRIP6,TRIO,SIRT7,PIK3R4,RSF1,CLINT1,CDC73,SLC1A1,YARS2,ABCA7,CHN1,DDX56,MCM5,CACNB2,WDR60,MED24,ANP32B,GEMIN4,MRPL21,CCDC88C,PRMT5,MAP3K12,TOMM34,FMNL2,MYB,NOM1,HMGCR,PEA15,GATAD2B,TIMM8B,BDNF,IFRD1,COL17A1,WDR61,STAG1,KCNQ3,MYO10,TSPYL4,RB1CC1,PRDM16,ARID5B,ATAT1,SMARCD3,MAP7D1,SNAP25,IMPDH2,CPT1A,TRIM37,ONECUT2,ABCF1,NCDN,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,FGFBP1,LEMD3,SURF1,KIAA0196,ARHGAP10,SRP14,DNM3,PAFAH1B1,ATP6V1A,ACTR3,VTI1A,DDR2,MYH9,ISG20L2,NUP43,STAM,EEA1,RPGRIP1L,ABCA12,ACD,ERI1,FMNL1,WAC,CLCN6,MMP14,CEP63,MSH4,PERP,LYST,KMT2D,EIF3J,NPM3,ASUN,ARHGEF10,ATP6V0A1,DSP,TTC28,FGFR1,PES1,TAF2,HLA-DMA,ARHGAP21,CDC16,KDM4B,ELP2,MISP,NSMCE2,HIPK2,ARL13B,BRCC3,YEATS2,LAMA5,RAB30,MAPT,HMGA2,SHQ1,XPC,SF3A3,JMJD6,ATG2B,GAS6,AKT1S1,TRIM22,TGFB2,PSMF1,MBNL1,POM121,TADA3,PSMG4,GATC,SUV39H2,TMSB10,NOP16,PVRL3,UNC13A,ANXA5,ACTR3B,SOX6,DIS3L2,SPTAN1,NUDC,DDHD1,FGF9,CEP83,VPS37A,ZC4H2,ARHGAP39,MRPS10,CCDC113,UBE2K,FOXC1,UBC,ANXA1,MRPL36,RPA1,NSD1,SRCAP,PXDN,POLE2,HERC1,ACOX1,BMP4,UQCC1,ANAPC4,CORO2B,KDM4C,CUL7,TRIM16,PPARGC1B,TFIP11,MFGE8,NREP,CSNK2A1,NLE1,SEC16A,COX10,BIRC2,ABL2,COPS4,ARHGAP18,MARVELD2,NCKIPSD,XRCC2,RAN,POLE3,ETV1,PTPRK,SF3A1,CDC37,FLNC,DBN1,CHD9,FMNL3,AEBP2,SKIV2L2,HARS,BAZ2A,CDK4,ANK2,KATNAL1,COL4A3BP,NOL6,PSMG1,ATG12,LAMA2,BRCA1,LSG1,MGST1,CXADR,CCDC28B,PEX1,BSN,GLS,HPRT1,ZNF622,TCF7L1,CHD3,PER1,E2F4,TNFRSF1A,RAD51B,AHNAK2,ADAM9,MAGI1,UQCC2,C2CD5,USP15,CHMP4C,TTN,MCM6,STX8,NKD2,MAPK8IP3,HSD17B10,LAMTOR3,SMAD7,ZIC2,RLF,DNAH1,ARID1B,SPIRE1,RNF40,ABCA5,CEP290,MBD2,VPS72,PPIL2,VAPB,CTR9,TIMELESS,WNT16,LRSAM1,TRAPPC9,LAMC1,USP49,IFT43,SETD2,HAUS6,BCS1L,UTP15,OBSCN,TRAPPC6B,SUPT5H,TCF7L2,NAP1L5,ATXN7,SPAG9,PALB2,SNAP23,TBPL1,NAPA,BRSK2,TESC,USP7,KCTD7,SART1,CYLD,ARID2,LPCAT2,RBFOX2,RPS29,SLC2A1,GPR143,PPP2R2A,RIPK1,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,PLXNB1,KDM1A,DENR,METTL16,NRF1,NUP133,GRIN2C,DNAJB6,IKBKB,ZDHHC6,HIRIP3,CCDC40,RNF2,ETF1,CORO1A,PRMT3,CTC1,PRPF19,SEC24A,KAT8,KDM3B,WDR36,EVL,TUBA1A,RAB7A,THSD4,C1QTNF1,VIM,TMEM123,NUP214,EIF3H,TJAP1,SMAD3,RANBP2,IFT81,RBBP8,TIMM17A,ITGA2,ATG7,NFASC,AP2S1,PARD3,NIFK,ESCO1,MINK1,KIZ,HM13,AGO2,ARFIP2,MAP1S,CSNK1A1,POGZ,HIST2H2AB,IQGAP2,ANXA7,PRICKLE2,HIST2H3D,DDX31,POLR1B,CD44,HSD17B12,AP4S1,SMARCAD1,TEX14,TOP3A,FERMT2,ARHGEF12,HIST1H4J,PALLD,RHOT2,CHCHD6,ZRANB3,MKX,DKK1,CENPP,CDH24,CACNB1,TMEM237,L3MBTL3,SET,MSH3,BCAS3,EIF2S1,NDUFAF5,MYRF,RBPJ,TAF12,ITGB4,CGN,MYCBP2,CUL4A,PRKAB2,ENAH,PRKCA,RAC3,LPIN1,EXOC1,RPS16,S100A10,CHD2,ME1,CEP135,SPAG6,SEH1L,ACADS,DPF3,SNU13,GDAP1,SETD1B,ATG9A,NOL8,EYA3,SEMA3F,CAMSAP2,SUPT20H,HIST1H2BL,ZDHHC14,SON,FOXRED1,CLNS1A,DOT1L,SKIL,TRRAP,LSM14A,LUC7L3,SEMA3C,CCNB1IP1,NRP1,BMI1,SPOCK2,NMD3,EFNB2,WDR75,IFT57,DROSHA,JUP,CDC42EP2,PRPF31,OPHN1,PID1,CCDC47,PRPF39,SSR4,CHD5,NDUFS7,FKBP1A,PRKCE,NAV1,HR,TSPAN2,USPL1,ASAP1,COPS3,MYC,MFAP2,CAV2,TERF2,SCAF11,USE1,EXOSC2,DDX28,SYNGAP1,PRIM2,ANAPC13,POLA1,RAP1GAP2,KIAA0586,RAP1B,ARID1A,MTR,ANGPTL4,ATP9B,SEC31A,CAT,ASCC3,EPRS,KIDINS220,NSF,HIF1A,VCAN,SRP68,PEX13,NCOR1,IQSEC2,SMYD3,VMA21,RTTN,PTCD2,SYT17,BIRC6,HFM1,C1QTNF7,PLEK2,CORO6,AP1B1,RING1,FLNB,NOP56,BLOC1S2,TERF2IP,NUBPL,CHD7,DECR1,SLX4,SHC1,KDM2A,PPID,DTNBP1,MRPS27,SSBP1,SERPINH1,KMT2A,SAP30,RFC4,CFAP221,MPP6,BRD4,RFC3,PDK1,MTIF2,WDPCP,PREX1,DLG4,LRRC8A,GNL1,SATB2,SETD7,POLG2,SERP1,SNCA,VDR,BAZ1A,MSX2,CAMK2D,SMARCC1,DCXR,DNAJA3,MBTD1,H2AFX,IFT140,MDN1,ANXA2,PDCD11,NOLC1,SETD6,TROVE2,MID1,SSH2,NCOR2,BRAF,UTP14A,C10orf2,TCF3,KIF5C,RTN4,MLH1,CEP126,MON2,OPA1,NOL3,IKBKAP,GDPD5,RPS6KA5,MAD2L2,NEDD4,DCTPP1,ABL1,NEBL,ELP5,TRIAP1,NISCH,PMPCA,PHYKPL,HARS2,RDX,COPS7B,NLGN3,CELF1,EXOSC4,DYNC2H1,PXN,TTLL5,APEX1,FZD3,KCNMA1,ADSL,BMS1,PACS1,PTK2,NOP58,INF2,KLHL22,COL26A1,ZDHHC11,STX18,SVIL,ATM,NDUFS5,APAF1,BRWD3,RABEP1,IPO4,KAT6A,STK4,IMMP2L,LETM1,EIF3C,UBN1,ATRX,NF1,KMT2E,RARS2,PTPRA,KIF5A,FANCD2,TRPM6,PLOD1,BCOR,SIRT2,CUTC,EDC3,SMARCB1,MRPS30,DST,SRPRB,ANAPC1,RAP1A,CNIH3,KANSL1,ATG3,ZNHIT6,ANAPC11,ANAPC10,MYH3,LONP1,TRIP13,CARM1,TIMM50,SRPK2,LAMA4,GPM6A,SESN2,SKAP2,SIRT6,ITPA,MINA,TMEM216,HDAC8,CAV1,KMT2C,TCTN1,ARPC3,CHAF1A,TIMM44,GEMIN5,RHOU,UBTF,PAF1,HLCS,CTAGE5,PQBP1,BBIP1,CLU,COPS6,NOCT,MTCH1,EMSY,SLC12A7,DCTN3,FBXO45,FN1,TAF1,SEC24D,VTA1,PAX2,PHGDH,TIMM10,DDIT4,TOX4,CEP164,P3H1,ATXN2,BANF1,ISPD,SEMA3D,PRF1,ATP6V0D1,POLR1E,RANBP6,KRT20,PPAT,JMJD1C,ELP3,WBSCR22,LIG4,PSMA1,EIF2A,SYT1,BLOC1S4,C19orf70,UBE2E1,EXOC6,BICD1,FSCN1,FAT1,SDCCAG8,HK2,EXOC4,SLC16A1,TBL1X,FNBP1L,PDSS2,AGO3,CHMP2A,ASH1L,FEZ2,PCNT,CELSR3,PSTPIP2,MYO7A,TNXB,SMARCA4,TBCCD1,COBLL1,PIBF1,GBF1,SBDS,MIEF1,VPS18,RRN3,KCTD11,MPHOSPH10,BRE,NVL,CBR4,ITGAX,MET,VCL,TMEM120B,TSPAN14,UTP4,HTRA2,RTN4RL2,PHLDB2,COL5A2,PTBP2,MRRF,METTL15,TOR1AIP2,ATP8B2,DKC1,RAB10,RAD54B,ARMC4,ALAD,KPNA3,ADNP,COPS5,SRFBP1,HEATR1,SCARB1,ARC,BRD9,TSPAN5,TMEM33,DNAJC2,TNIK,SUPT6H,DYM,H2AFJ,ATF7IP,CHCHD10,SEMA3E,GFM2,SFI1,MRPS11,PEX7,SCN1B,HAS3,SEC24C,DSG2,SHMT2,TTC17,ERI3,FBL,AMOT,DMRT1,MICAL3,TOP1,KDM6B,PPP1R9B,MSX1,GPHN,KDM5B,FGF2,KDM5A,SCMH1,PDE2A,MEN1,PEAK1,RERE,MFN2,GADD45A,WDR35,MPP7,AGTPBP1,VPS37B,NCBP2,ZAK,MMP16,ZSWIM6 |
| 1.411e-11 | -24.98 | organic cyclic compound biosynthetic process | biological process | GO:1901362 | 3149 | 526 | 16441 | 2138 |
ASCC1,CACNA1H,HLTF,CCNL2,ZNF44,NUP160,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,ATP5G2,ZNF148,KDM5C,ZNRD1,FXN,HMBOX1,RNMT,UPP1,NFIA,RFX2,C5AR1,ZNF197,STOML2,PYCR1,DDX3X,ZNF266,SUPT4H1,RAD18,RUNX1,ZNF532,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ZNF326,MED24,PRMT5,ZNF518B,MYB,HMGCR,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,ZNF512B,USP10,SMARCD3,IMPDH2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,GTF2A1,NME7,RPL28,CDK9,SURF1,CCDC85B,ZNF160,CNOT6,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,SAFB2,ZKSCAN1,PYCRL,WAC,MTHFD2L,LSM10,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,MEF2D,SLC35D1,MAT2A,FGFR1,TAF2,KDM4B,ELP2,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,INSIG2,ID2,JMJD6,TRIM22,BHLHE40,TGFB2,POM121,TADA3,SNW1,POLR3D,SUV39H2,TAF3,ZNF710,SOX6,POLK,ZNF467,FOXC1,UBC,RPA1,TRIB3,NSD1,SRCAP,BAZ2B,POLE2,ARID3B,SRD5A3,KDM4C,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,COX10,BIRC2,AMPD3,SRSF2,PHF5A,HKR1,PPCDC,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,CHD9,ATF4,AEBP2,ZNF124,PPARG,ZNF414,BAZ2A,MED27,BRCA1,ZNF91,MLLT10,GLS,LSS,HPRT1,TCF7L1,INSIG1,TP53BP1,CHD3,E2F4,PER1,DLX2,BEND6,SARS,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,ALDH18A1,GMDS,NT5E,PAXBP1,TLE3,SETD2,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,TBPL1,ZNF430,HMBS,MPI,ID1,SUCLG1,ARID2,RPS29,ZNF83,ZNF709,PELP1,ZNF121,FDX1,KDM1A,CAD,NRF1,ZBTB21,IDI1,NUP133,ZFP37,RNF2,KAT8,KDM3B,PCGF3,CPOX,NUP214,ZNF251,ATP5D,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ATG7,ZNF436,MED20,ZNF18,ZNF507,NIFK,RFX1,AGO2,APRT,FOXP1,ZNF594,ZNF561,POLR1B,HSD17B12,SNAPC5,TRNP1,ZNF654,FOXN3,ZMYM5,POLR3A,POLR3G,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,POLB,MYCBP2,CUL4A,PRKAB2,GABPB2,MGA,LPIN1,RPS16,RNF111,CHD2,ME1,MEIS3,SEH1L,ZNF646,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,DENND4A,SAP30BP,GZF1,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,ZHX3,GTF2IRD1,CHD5,HR,ZNF586,SCAF1,ATIC,MYC,GTF3C3,PRPS1,FDFT1,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,ZNF425,ASCC3,MTHFD2,HIF1A,SPEN,ZBTB12,MED15,SQLE,PURB,UMPS,NCOR1,DHCR7,ZFHX2,ZNF254,ZBTB37,UROD,FOSL2,RING1,TERF2IP,FLAD1,CHD7,ZNF827,KDM2A,UCHL5,LPIN2,CMPK1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,SATB2,MED16,PNN,SETD7,POLG2,HSD3B7,ZBTB25,SNCA,BAZ1A,VDR,DNTTIP1,MSX2,SMARCC1,G6PD,ZNF236,MBTD1,TROVE2,NCOR2,C10orf2,TCF3,ZNF280C,NFX1,MYNN,LIAS,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,YBX3,FAM120B,TSHZ1,TTLL5,APEX1,PSAT1,ADSL,KLF6,MMAA,POLR2A,ZFP62,ZNF155,ADK,DDIT3,KAT6A,ZNF76,PHF3,MVK,KMT2E,ATRX,RCHY1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,POLR3B,SLC27A5,CARM1,TRIP13,ELOF1,ZBTB17,DEAF1,SESN2,ZNF195,TXLNG,ZNF680,MINA,HDAC8,MTHFD1L,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,GATA6,CC2D1B,MKL2,PQBP1,CRCP,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,AK2,TAF1,PAX2,DPF2,MED13L,DDIT4,NAMPT,ELL,ZNF354A,NRIP1,POLR1E,ZNF629,MTHFD1,VOPP1,ZNF234,TSTA3,PPAT,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,LIG4,PRDM1,ISG15,MYBBP1A,FDPS,RRAGA,ZFP90,TBL1X,NR2C2AP,ZBTB24,TCF12,ASH1L,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,TMEM14C,UTP4,MAML3,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,BATF3,TPK1,IKZF4,ALAD,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,PPHLN1,CHCHD10,ATF7IP,MED18,GART,DMRT1,PKNOX1,ARNTL2,MSX1,GPHN,KDM5B,ZNF821,TEAD1,KDM5A,PSPC1,ZNF324B,SCMH1,MEN1,ZNF407,ZNF221,RERE,ZNF708,NCBP2,NFKBIB,POLR1C |
| 1.453e-11 | -24.95 | heterocycle biosynthetic process | biological process | GO:0018130 | 3024 | 508 | 16441 | 2138 |
ZNF292,POLB,MYCBP2,ASCC1,CUL4A,PRKAB2,HLTF,CCNL2,ZNF44,NUP160,GABPB2,LPIN1,MGA,SKI,ZNF37A,RPS16,SREBF2,IKZF5,ZFHX3,ATP5G2,RNF111,ME1,ZNF148,CHD2,KDM5C,MEIS3,ZNRD1,FXN,SEH1L,ZNF646,DPF3,HMBOX1,SETD1B,RNMT,NR6A1,UPP1,EYA3,NFIA,TCEB3,CUX1,RFX2,C5AR1,DENND4A,SAP30BP,ZNF197,STOML2,GZF1,PYCR1,DDX3X,SKIL,ZNF266,TRRAP,SUPT4H1,RAD18,CCNT1,ZNF81,HIC2,RUNX1,BMI1,ZNF532,PTPN14,MEF2C,BANP,IFT57,EGR1,TRIP6,ZHX3,KHDRBS1,SIRT7,GTF2IRD1,RSF1,CDC73,CHD5,HR,ZNF586,SCAF1,MYC,ATIC,ZNF326,MED24,GTF3C3,PRMT5,ZNF518B,PRPS1,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,PRIM2,RREB1,ZNF587,RB1CC1,PRDM16,POLA1,ARID5B,ZNF512B,USP10,SMARCD3,IMPDH2,ARID1A,NELFA,TRIM37,ONECUT2,SRA1,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,ASCC3,MTHFD2,GTF2A1,NME7,RPL28,HIF1A,CDK9,SPEN,MED15,ZBTB12,SURF1,CCDC85B,ZNF160,PURB,UMPS,CNOT6,NCOR1,ZFHX2,ZNF254,ZNF516,TRERF1,GTF2H2C,NPAS2,ZBTB37,UROD,NUP43,FOSL2,SAFB2,RING1,TERF2IP,CHD7,FLAD1,ZNF827,KDM2A,ZKSCAN1,PYCRL,UCHL5,WAC,LPIN2,CMPK1,KMT2A,MTHFD2L,LSM10,CASP8AP2,SAP30,RFC4,RFC3,BRD4,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,SATB2,MED16,MEF2D,PNN,SETD7,SLC35D1,POLG2,MAT2A,FGFR1,ZBTB25,VDR,TAF2,BAZ1A,DNTTIP1,MSX2,SMARCC1,KDM4B,ELP2,HIPK2,G6PD,ZNF236,MBTD1,POLR3E,HOXA3,ZBTB11,TROVE2,COMMD10,HMGA2,NCOR2,ZNF786,C10orf2,TCF3,ZNF280C,NFX1,ID2,JMJD6,MYNN,LIAS,TRIM22,BHLHE40,IKBKAP,FOXO3,MAD2L2,POM121,SFR1,ZNF483,TADA3,ZNF239,SNW1,POLR3D,COMMD9,PTRF,SUV39H2,ELP5,TAF3,YBX3,ZNF710,SOX6,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,POLK,ADSL,ZNF467,KLF6,MMAA,FOXC1,UBC,POLR2A,RPA1,ZFP62,TRIB3,NSD1,SRCAP,BAZ2B,ZNF155,POLE2,ARID3B,ADK,DDIT3,KDM4C,KAT6A,ZNF76,PHF3,GPBP1L1,ATRX,KMT2E,PPARGC1B,POLR1A,RCHY1,CSNK2A1,ZNF107,BCOR,SIRT2,COX10,SNAPC4,BIRC2,SMARCB1,AMPD3,SRSF2,PHF5A,YLPM1,JAZF1,HKR1,PPCDC,RELB,ZEB1,POLR3B,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,SESN2,ZNF124,TXLNG,ZNF195,PPARG,ZNF680,ZNF414,BAZ2A,MED27,MINA,HDAC8,MTHFD1L,BRCA1,KMT2C,SOX4,ZSCAN2,ZNF91,MLLT10,TAF9B,PAF1,GLS,UBTF,HPRT1,TCF7L1,GATA6,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,PQBP1,CRCP,DLX2,ZC3H8,ZNF397,BEND6,NOCT,DMTF1,EMSY,SARS,AK2,FOXO1,TAF1,PAX2,DPF2,LAMTOR3,SMAD7,HES6,MED13L,BARX2,ZIC2,RLF,ARID1B,NAMPT,DDIT4,ELL,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,ALDH18A1,GMDS,NRIP1,POLR1E,NT5E,MTHFD1,ZNF629,VOPP1,ZNF234,PAXBP1,TSTA3,PPAT,TLE3,JMJD1C,ELP3,SETD2,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,SUPT5H,ISG15,TCF7L2,NR2F1,PWP1,ATXN7,MYBBP1A,RRAGA,TBPL1,ZNF430,ZFP90,HMBS,TBL1X,ZBTB24,NR2C2AP,TCF12,MPI,ID1,ASH1L,SUCLG1,ARID2,RPS29,SMARCA4,PBX1,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,ZSCAN5A,CAD,RRN3,NRF1,ZBTB21,CAMTA2,NUP133,ZNF142,ZFP37,RNF2,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,MAML3,KAT8,KDM3B,PCGF3,PRAME,TFCP2,SFSWAP,CPOX,GRHL3,ATXN1,POU2F1,NUP214,ZNF251,ATP5D,TPK1,BATF3,SMAD3,RANBP2,ALAD,IKZF4,ADNP,SIX5,COPS5,ZNF557,KLF4,ZNF333,ARNTL,CEBPZ,ATG7,ZNF436,SRFBP1,NFRKB,MED20,ZNF18,BRD9,ZNF507,DNAJC2,NIFK,SUPT6H,RFX1,AGO2,PPHLN1,APRT,MED18,ATF7IP,CHCHD10,FOXP1,ZNF594,GART,ZNF561,POLR1B,DMRT1,PKNOX1,SNAPC5,ARNTL2,MSX1,TRNP1,KDM5B,GPHN,ZNF821,TEAD1,ZNF654,PSPC1,FOXN3,KDM5A,ZMYM5,SCMH1,ZNF324B,MEN1,ZNF407,POLR3A,RERE,ZNF221,POLR3G,ZNF708,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,NCBP2,ZNF32,MYRF,RBPJ,TAF12,POLR1C,NFKBIB,NR2F2 |
| 2.004e-11 | -24.63 | catalytic complex | cellular component | GO:1902494 | 1048 | 207 | 17570 | 2233 |
CUL7,CUL4A,KMT2E,PRKAB2,POLR1A,PLRG1,RCHY1,CSNK2A1,CCNL2,MGA,ANAPC1,PHKA1,KANSL1,ATG3,ANAPC11,ANAPC10,UBAP2L,IPP,POLR3B,POLE3,NDUFA6,ZNRD1,CDK6,PRKACB,METTL1,RBCK1,AEBP2,FBXW4,SETD1B,KLHL23,CDK4,GNG7,MED27,HDAC8,SUPT20H,DCUN1D5,BRCA1,KRTCAP2,KMT2C,FOXRED1,DLST,CLNS1A,SPOP,TAF9B,GNAI1,PAF1,TRRAP,RAD18,CCNT1,CHD3,CRCP,DNAH2,TSEN2,BMI1,DCAF5,WDR75,EP400,DROSHA,PRPF31,TAF1,PIK3R4,DPM3,TGFBR2,DNAH1,CDC73,CHD5,NDUFS7,ABCA7,TOX4,RNF40,HR,INTS7,MBD2,GTF2H1,MED24,CTR9,PRMT5,NRIP1,AGL,POLR1E,PRPS1,CPSF3L,GATAD2B,NAA38,GTF2H3,ANAPC13,WDR61,RB1CC1,POLA1,ELP3,BCS1L,TRIM37,VAC14,DNAH14,ARIH2,UBE2E1,IRS1,POP1,DYNC1H1,ATXN7,GTF2A1,CDK9,INTS5,DNAH17,TBPL1,SENP3,TBL1X,NCOR1,PDSS2,PRKAR2A,AGO3,BCCIP,NDUFA5,PAPD4,SUCLG1,NDUFB5,KLHL18,PPP2R2A,RIPK1,POP5,EEA1,HSPA1A,PELP1,RING1,NDUFB3,PHC2,RPP30,FARSA,BRE,UBR1,UCHL5,IKBKB,INTS12,RNF2,KMT2A,NAA35,CDK12,GNG5,CASP10,AUP1,SAP30,KAT8,KMT2D,BRD4,PDK1,SATB2,MARCH6,ENC1,ERC1,MAT2A,SNCA,TAF2,GNG2,FBXL5,DNTTIP1,CDC16,ELP2,DNAJA3,POLR3E,INTS9,MED20,NFRKB,BRCC3,YEATS2,KLHL24,BCKDK,NCOR2,MAP3K13,AGO2,MED18,IKBKAP,MAD2L2,NEDD4,TADA3,SNW1,POLR3D,NDUFV1,TAF3,DCTN4,DYNC2H1,POLR1B,FBXO31,FBXL19,FBXO17,PPP1R9B,KDM5A,ABCF2,MEN1,PIK3CB,POLR3A,POLR2A,POLR3G,HSPA1B,RERE,FBXO21,KLHL22,POLE2,ADAT2,CUL2,TAF4,FNTB,NDUFS5,TAF12,POLR1C,ANAPC4,GCSH,KAT6A |
| 2.223e-11 | -24.53 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 719 | 155 | 17758 | 2279 |
IMMP2L,TMEM109,ADAMTS6,PPIL1,TMEM132A,BIRC2,GABPB2,MRPS30,ZNF37A,MMP7,DHX33,ATP5G2,MARVELD2,RABGAP1L,JAZF1,GPR87,PCOLCE2,SLC27A5,LYRM5,OGG1,PPM1K,SEH1L,VPS13B,AEBP2,LIMA1,KATNAL1,PTPRM,GDPD1,GMFB,MINA,NFIA,DCUN1D5,PITPNB,HIST1H2BL,DDX60,OSBPL1A,GLS,GATA6,SH3RF1,FAM206A,LUC7L3,LRRC40,PPP3CC,WDR66,DMTF1,TMEM158,OXNAD1,EGR1,SEC24D,CCDC53,LAMTOR3,TATDN3,DPM3,ANXA10,TSPAN2,CEP290,SEMA3D,CCDC167,SAMD13,NOC3L,PRIM2,PTPN12,ZNFX1,ONECUT2,USP46,DNAH14,ISG15,ZNF783,PWP1,FAM135A,SYNCRIP,PMEPA1,HK2,TBPL1,PEX13,ARHGAP12,PTP4A2,N4BP2L2,HS2ST1,TCF12,PAPD4,CCDC58,PAFAH1B1,NDUFB5,SPATS2L,ST3GAL6,DDX60L,FDX1,CHD7,UBR1,CBR4,PPFIBP1,HIBCH,ATP6AP1L,PRMT3,PLEKHA4,HN1,PRAME,PDK1,ZNF480,SATB2,SLC35F2,PNN,ATP8B2,POLG2,ARL5B,USP36,ZBTB25,COPS5,TIMM17A,DUSP19,XRCC4,METTL2B,CEP170,YEATS2,ZNF507,TNIK,ESCO1,INSIG2,B4GALT5,SLC25A12,ID2,TRIM22,ENOX1,HIST2H2AB,GFM2,PVRL3,IFIT5,TANK,CELF1,CD44,SAMD4A,TMC7,ZC4H2,PPP1R21,USP42,FERMT2,OASL,GPNMB,KLF6,TMEM187,MMAA,ETFDH,DDX50,GADD45A,MPP7,WDR35,ADAT2,EIF2S1,RBM26,RBPJ,TATDN1,RPS6KC1,KDM4C,ANAPC4 |
| 3.174e-11 | -24.17 | GCM_MAP4K4 | MSigDB lists | GCM_MAP4K4 | 166 | 54 | 17758 | 2279 |
HERC2,SNX27,TNIK,ANKRD17,MAPK8IP3,FAN1,RTN4,SIRT2,ABHD6,POGZ,SPIRE1,MTUS1,RNF141,PDZD2,RASSF3,VPS52,RDX,GLTP,CLDND1,RAN,AHCYL1,ZNF710,FMNL2,KDM3B,FADS1,HMBOX1,SIK3,PSAT1,TSPYL4,MYO10,AGPAT4,PREX1,ZFP14,TTYH2,LRRC8A,PTK2,UBE2K,TRIM37,PEAK1,USP46,TJAP1,GZF1,DYNC1H1,ZFAND3,FBXO21,ARHGAP21,EIF4ENIF1,SPAG9,KIDINS220,HIPK2,CLEC16A,PREPL,TBCK,KIF1B |
| 3.349e-11 | -24.12 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | 488 | 115 | 17758 | 2279 |
SRM,ZNF516,PRDX6,ARID2,C16orf45,NAT10,PBX1,SLC29A1,TUBB6,PTPRG,PABPC1L,CSTA,AARS,SEMA6A,PABPC4,IGSF1,FLNB,DST,CAD,ASNS,ABCA12,DHX33,VGF,SLC38A2,HIRIP3,ZNRD1,PPM1K,EVL,SLC38A1,GLTSCR2,THSD4,CDK4,LGALS1,NLN,ATXN1,CAV1,ATP8B2,DSP,ERC1,FKBP3,SLC7A1,HPRT1,RBBP8,ELP2,ARL4A,ITGA2,LARGE,AHNAK2,BDH2,BBIP1,FKBP5,CCNB1IP1,PKIB,MAPT,YDJC,SARS,UTP14A,C1orf226,H2AFJ,ZIC2,QSER1,PPP1R1C,PIP4K2A,RSRC1,BZW2,HDDC2,DCTPP1,C6orf48,TAF3,VPS72,MYC,ATIC,STC2,CCDC112,SHMT2,GREB1,ANP32B,PCK2,FBL,LDLRAD3,PRMT5,NRIP1,LPCAT1,RPL22L1,CLK2,MTHFD1,MSI2,APEX1,GINS3,EPS15L1,BCS1L,ADSL,IMPDH2,HIST1H4J,PALLD,SYT1,PLCB1,NOP58,DKK1,IRS1,UBAP2,SNX24,CCDC85B,EIF2S1,SVIL,DNAJC12,DTD1,RWDD2B,TBL1X,NR2F2,MB21D2,ADK,SMYD3,GPATCH4,NR2C2AP |
| 3.749e-11 | -24.01 | acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_B_cell_leukaemia | 3979 | 634 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,CNTNAP3,NAT10,CACNA1H,SBF2,CSPP1,HLTF,HMOX2,NUP160,AMBRA1,SKI,TOM1L1,PCDH7,C1orf159,PDZD2,SYN2,RASSF3,RABGAP1L,AP1M1,MAD1L1,ZNF148,KDM5C,HRG,CDK6,CNTNAP3B,NRAS,PTPRM,UPP1,NFIA,KIF15,SHISA5,ABCC2,RBM28,RUNX1,VASH2,ZNF532,SLC25A26,MEF2C,HERC2,TMEM63C,TRIO,NHS,PIK3R4,RSF1,CDC73,ABCA7,SLC39A11,RSPRY1,SH2B3,RBM20,CNST,SLC38A5,KIAA1671,APLF,MCM5,CCDC88C,CALN1,MAP3K12,PABPC1,FMNL2,MYB,LRRC20,STAG1,MYO10,RB1CC1,PRDM16,TYW1,EIF4A2,RYR2,ST6GALNAC3,SNAP25,CPT1A,EVI5,MBNL2,DYNC1H1,VPS13C,LRP1B,TASP1,GTF2A1,CNOT6,BPNT1,WDR33,PDLIM5,ARHGAP10,COG5,SPRED2,ABCA3,DNM3,NPAS2,PDK4,LCLAT1,STAM,RPGRIP1L,CD96,ABCA12,TBC1D22A,FMNL1,WAC,CEP63,PEG10,ZC3H3,KMT2D,ZNF480,ADAM32,SLC35D1,TTC28,DSP,VPS53,FGFR1,ZFAND3,GNG2,IQCH,ELP2,KDM4B,ASTN2,NSMCE2,CAMKMT,WDR7,FUS,ZBTB11,LAMA5,METTL2B,LRCH1,SHQ1,XRRA1,ATG2B,AKT1S1,RSRC1,MBNL1,TAF3,CFDP1,PVRL3,ACAP3,UNC13A,ANXA5,FBXL19,C15orf41,SAMD4A,SOX6,HNRNPM,DIS3L2,ULBP1,DDHD1,C21orf58,FAM98A,ERICH1,ZC3H18,FRA10AC1,NXN,RSBN1,R3HDM2,PPIP5K2,ANXA1,RPA1,PXDN,HERC1,PTPN4,SORCS2,MTMR1,WDR13,MFGE8,SLC25A21,GIT2,SCAF8,AMPD3,ECM1,SRSF2,DHX33,MARVELD2,ANKRD11,UBAP2L,SLC25A23,ZMYM2,ETV1,MPST,VPS13B,FAM184A,FLNC,DSC3,DBN1,FMNL3,ABCC4,MIOS,SKIV2L2,KATNAL1,ANK2,GDPD1,LAMA2,DLST,PEX1,BSN,HPRT1,INSIG1,TP53BP1,CHD3,EEFSEC,E2F4,ADAM9,DPP4,PPP3CC,TSEN2,MAGI1,USP15,XYLB,FOXO1,STX8,ITFG1,PRSS3,NKD2,MAPK8IP3,BARX2,RLF,ARID1B,DOPEY1,ABCA5,CEP290,MBD2,SAMD11,NDRG4,TIMELESS,GMDS,SNX29,NIPSNAP1,TRAPPC9,CAMKK2,SETD2,OBSCN,ACOXL,VAC14,GRIK4,TTC38,DNAH17,SNX24,SIL1,DTD1,SH3PXD2A,USP7,CYLD,OLFM2,UPK3B,NDUFAF2,RBFOX2,SSBP2,RADIL,PPP1R9A,ZNF121,URB1,PAG1,KDM1A,CAD,METTL16,ZNF608,NUP133,FGGY,ANKRD24,CCDC40,BCAP29,AHCYL1,CASP10,CTC1,KDM3B,TLCD1,SOBP,WDR36,PCGF3,THSD4,RAB7A,AKAP13,EIF3H,USP36,BTBD11,RANBP2,TIMM17A,CLEC16A,ATG7,TSSC1,INTS9,ZNF589,PARD3,MAP3K13,FOXP1,POGZ,BZW2,IQGAP2,SACS,CWC27,PRICKLE2,DDX31,POLR1B,ADAMTSL3,DHX34,FERMT2,PALLD,EXOG,RHOT2,CHCHD6,PIK3CB,ARMC3,POLR3A,NOL10,DSC2,L3MBTL3,BCAS3,MSH3,RBM26,ITGB4,RPS6KC1,XPO6,MIPOL1,LMBRD2,CGN,PRKCSH,TNFRSF21,PLRG1,GYG1,LPIN1,ZFYVE28,RNF111,ME1,CHD2,CEP135,MEIS3,TBC1D8,GDAP1,OSBP2,NR6A1,CUX1,CAMSAP2,ZDHHC14,DDX60,CLNS1A,SPOP,GNAI1,GZF1,SKIL,TRRAP,SH3RF1,CFD,HIC2,VPS13D,GREB1L,NRP1,ZNF598,PTPN14,DROSHA,CELSR1,ZHX3,ANKRD17,TATDN3,OPHN1,PID1,CD226,IGF2BP3,ANXA10,PRKCE,TECTA,NAV1,ASAP1,PIGG,SAMD13,CNOT4,LPCAT1,PRPS1,FDFT1,PRIM2,PCCA,POLA1,RAPGEF4,EHBP1,PLCB1,ARIH2,PHF6,ATP9B,CAT,ASCC3,UBAP1,VCAN,SPEN,SQLE,C7orf50,UMPS,NCOR1,MACROD1,MAP2K4,ZFHX2,HS2ST1,RTTN,AMOTL1,TRPM2,SYT17,HFM1,PTPRG,PDE3A,TRIM66,CHD7,ZNF827,LPIN2,VGF,DTNBP1,NBEA,CMPK1,PLEKHA4,NAA35,CASP8AP2,RFC3,MPP6,PDK1,MTIF2,WDPCP,SATB2,MARCH6,SETD7,POLG2,STK10,DHX57,MSX2,ZNF236,LARGE,CBWD1,IFT140,MDN1,MID1,NCOR2,BRAF,SCAMP3,TTC27,CA11,B4GALT5,TCF3,ZNF280C,FARS2,RCAN1,MLH1,MON2,GIGYF2,ABL1,NEBL,LRP2BP,PMPCA,DYNC2H1,NAV3,TSHZ1,FER1L5,TMC7,SLC40A1,WDFY3,AGPAT4,PACS1,GUF1,YIF1A,FBXO21,RETSAT,IREB2,DDX50,ZDHHC11,HELZ,SVIL,ATM,MYOM2,APAF1,BRWD3,IMMP2L,LETM1,PHF3,LYRM4,NF1,ATRX,RARS2,ANKRD18A,STK33,SMARCB1,DST,ZNF804A,RTN1,YLPM1,CNIH3,JAZF1,ANAPC11,RELB,ZEB1,KIAA0922,POLR3B,PCOLCE2,SLC35C2,CEP128,LAMA4,DTNB,GPM6A,FBXW4,SKAP2,SLC38A1,ARRDC3,TFPI,KSR2,HDAC8,CAV1,SOX4,KMT2C,ST3GAL5,SERGEF,CDHR3,PAF1,GEMIN5,TMEM132B,UBTF,HLCS,DNAJC1,MKL2,CSMD3,ABCC3,GALNT10,ZNF397,COPS6,SLC12A7,FN1,RHOBTB1,STXBP6,DPF2,MED13L,EVPL,QSER1,PHGDH,ETFB,ZNF354A,ISPD,CCDC112,SEMA3D,CCDC124,CPSF3L,MTHFD1,ELP3,JMJD1C,WWC1,PRDM1,CORIN,SYT1,AGAP1,EXOC6,MYBBP1A,FAT1,SDCCAG8,HK2,EXOC4,CDKAL1,TMEM117,KIAA1328,TMEM182,FNBP1L,PDE9A,PDSS2,TCF12,DMXL2,ASH1L,PCNT,SLC5A5,MMRN2,SMARCA4,ARSJ,PIBF1,DHX35,RRN3,FARSA,BRE,SOCS1,CCDC50,LYPLAL1,SNTG2,FHIT,MET,VCL,TMEM120B,TMEM14C,AUP1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,EDEM2,UBR4,TPK1,ARMC4,KPNA3,ADNP,CEBPZ,SRFBP1,NFRKB,USP11,TSPAN5,SMG1,TNIK,SUPT6H,DYM,PDE4B,CLSTN2,ATF7IP,SEMA3E,PPP1R1C,ENOX1,BMP6,MAN1A1,PRKCH,DSG2,TTC17,ERI3,FBL,LDLRAD3,AMOT,DMRT1,KDM6B,DNMBP,FGF2,ZNF821,PPP1R21,SCFD2,MARS,PHACTR2,PDE2A,LENG8,EIF5B,ZNF407,NAALADL2,SYMPK,RERE,WDR35,AGTPBP1,CUL2,MBD6,MMP16,SLC16A10,ZSWIM6 |
| 3.749e-11 | -24.01 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | 3979 | 634 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,CNTNAP3,NAT10,CACNA1H,SBF2,CSPP1,HLTF,HMOX2,NUP160,AMBRA1,SKI,TOM1L1,PCDH7,C1orf159,PDZD2,SYN2,RASSF3,RABGAP1L,AP1M1,MAD1L1,ZNF148,KDM5C,HRG,CDK6,CNTNAP3B,NRAS,PTPRM,UPP1,NFIA,KIF15,SHISA5,ABCC2,RBM28,RUNX1,VASH2,ZNF532,SLC25A26,MEF2C,HERC2,TMEM63C,TRIO,NHS,PIK3R4,RSF1,CDC73,ABCA7,SLC39A11,RSPRY1,SH2B3,RBM20,CNST,SLC38A5,KIAA1671,APLF,MCM5,CCDC88C,CALN1,MAP3K12,PABPC1,FMNL2,MYB,LRRC20,STAG1,MYO10,RB1CC1,PRDM16,TYW1,EIF4A2,RYR2,ST6GALNAC3,SNAP25,CPT1A,EVI5,MBNL2,DYNC1H1,VPS13C,LRP1B,TASP1,GTF2A1,CNOT6,BPNT1,WDR33,PDLIM5,ARHGAP10,COG5,SPRED2,ABCA3,DNM3,NPAS2,PDK4,LCLAT1,STAM,RPGRIP1L,CD96,ABCA12,TBC1D22A,FMNL1,WAC,CEP63,PEG10,ZC3H3,KMT2D,ZNF480,ADAM32,SLC35D1,TTC28,DSP,VPS53,FGFR1,ZFAND3,GNG2,IQCH,ELP2,KDM4B,ASTN2,NSMCE2,CAMKMT,WDR7,FUS,ZBTB11,LAMA5,METTL2B,LRCH1,SHQ1,XRRA1,ATG2B,AKT1S1,RSRC1,MBNL1,TAF3,CFDP1,PVRL3,ACAP3,UNC13A,ANXA5,FBXL19,C15orf41,SAMD4A,SOX6,HNRNPM,DIS3L2,ULBP1,DDHD1,C21orf58,FAM98A,ERICH1,ZC3H18,FRA10AC1,NXN,RSBN1,R3HDM2,PPIP5K2,ANXA1,RPA1,PXDN,HERC1,PTPN4,SORCS2,MTMR1,WDR13,MFGE8,SLC25A21,GIT2,SCAF8,AMPD3,ECM1,SRSF2,DHX33,MARVELD2,ANKRD11,UBAP2L,SLC25A23,ZMYM2,ETV1,MPST,VPS13B,FAM184A,FLNC,DSC3,DBN1,FMNL3,ABCC4,MIOS,SKIV2L2,KATNAL1,ANK2,GDPD1,LAMA2,DLST,PEX1,BSN,HPRT1,INSIG1,TP53BP1,CHD3,EEFSEC,E2F4,ADAM9,DPP4,PPP3CC,TSEN2,MAGI1,USP15,XYLB,FOXO1,STX8,ITFG1,PRSS3,NKD2,MAPK8IP3,BARX2,RLF,ARID1B,DOPEY1,ABCA5,CEP290,MBD2,SAMD11,NDRG4,TIMELESS,GMDS,SNX29,NIPSNAP1,TRAPPC9,CAMKK2,SETD2,OBSCN,ACOXL,VAC14,GRIK4,TTC38,DNAH17,SNX24,SIL1,DTD1,SH3PXD2A,USP7,CYLD,OLFM2,UPK3B,NDUFAF2,RBFOX2,SSBP2,RADIL,PPP1R9A,ZNF121,URB1,PAG1,KDM1A,CAD,METTL16,ZNF608,NUP133,FGGY,ANKRD24,CCDC40,BCAP29,AHCYL1,CASP10,CTC1,KDM3B,TLCD1,SOBP,WDR36,PCGF3,THSD4,RAB7A,AKAP13,EIF3H,USP36,BTBD11,RANBP2,TIMM17A,CLEC16A,ATG7,TSSC1,INTS9,ZNF589,PARD3,MAP3K13,FOXP1,POGZ,BZW2,IQGAP2,SACS,CWC27,PRICKLE2,DDX31,POLR1B,ADAMTSL3,DHX34,FERMT2,PALLD,EXOG,RHOT2,CHCHD6,PIK3CB,ARMC3,POLR3A,NOL10,DSC2,L3MBTL3,BCAS3,MSH3,RBM26,ITGB4,RPS6KC1,XPO6,MIPOL1,LMBRD2,CGN,PRKCSH,TNFRSF21,PLRG1,GYG1,LPIN1,ZFYVE28,RNF111,ME1,CHD2,CEP135,MEIS3,TBC1D8,GDAP1,OSBP2,NR6A1,CUX1,CAMSAP2,ZDHHC14,DDX60,CLNS1A,SPOP,GNAI1,GZF1,SKIL,TRRAP,SH3RF1,CFD,HIC2,VPS13D,GREB1L,NRP1,ZNF598,PTPN14,DROSHA,CELSR1,ZHX3,ANKRD17,TATDN3,OPHN1,PID1,CD226,IGF2BP3,ANXA10,PRKCE,TECTA,NAV1,ASAP1,PIGG,SAMD13,CNOT4,LPCAT1,PRPS1,FDFT1,PRIM2,PCCA,POLA1,RAPGEF4,EHBP1,PLCB1,ARIH2,PHF6,ATP9B,CAT,ASCC3,UBAP1,VCAN,SPEN,SQLE,C7orf50,UMPS,NCOR1,MACROD1,MAP2K4,ZFHX2,HS2ST1,RTTN,AMOTL1,TRPM2,SYT17,HFM1,PTPRG,PDE3A,TRIM66,CHD7,ZNF827,LPIN2,VGF,DTNBP1,NBEA,CMPK1,PLEKHA4,NAA35,CASP8AP2,RFC3,MPP6,PDK1,MTIF2,WDPCP,SATB2,MARCH6,SETD7,POLG2,STK10,DHX57,MSX2,ZNF236,LARGE,CBWD1,IFT140,MDN1,MID1,NCOR2,BRAF,SCAMP3,TTC27,CA11,B4GALT5,TCF3,ZNF280C,FARS2,RCAN1,MLH1,MON2,GIGYF2,ABL1,NEBL,LRP2BP,PMPCA,DYNC2H1,NAV3,TSHZ1,FER1L5,TMC7,SLC40A1,WDFY3,AGPAT4,PACS1,GUF1,YIF1A,FBXO21,RETSAT,IREB2,DDX50,ZDHHC11,HELZ,SVIL,ATM,MYOM2,APAF1,BRWD3,IMMP2L,LETM1,PHF3,LYRM4,NF1,ATRX,RARS2,ANKRD18A,STK33,SMARCB1,DST,ZNF804A,RTN1,YLPM1,CNIH3,JAZF1,ANAPC11,RELB,ZEB1,KIAA0922,POLR3B,PCOLCE2,SLC35C2,CEP128,LAMA4,DTNB,GPM6A,FBXW4,SKAP2,SLC38A1,ARRDC3,TFPI,KSR2,HDAC8,CAV1,SOX4,KMT2C,ST3GAL5,SERGEF,CDHR3,PAF1,GEMIN5,TMEM132B,UBTF,HLCS,DNAJC1,MKL2,CSMD3,ABCC3,GALNT10,ZNF397,COPS6,SLC12A7,FN1,RHOBTB1,STXBP6,DPF2,MED13L,EVPL,QSER1,PHGDH,ETFB,ZNF354A,ISPD,CCDC112,SEMA3D,CCDC124,CPSF3L,MTHFD1,ELP3,JMJD1C,WWC1,PRDM1,CORIN,SYT1,AGAP1,EXOC6,MYBBP1A,FAT1,SDCCAG8,HK2,EXOC4,CDKAL1,TMEM117,KIAA1328,TMEM182,FNBP1L,PDE9A,PDSS2,TCF12,DMXL2,ASH1L,PCNT,SLC5A5,MMRN2,SMARCA4,ARSJ,PIBF1,DHX35,RRN3,FARSA,BRE,SOCS1,CCDC50,LYPLAL1,SNTG2,FHIT,MET,VCL,TMEM120B,TMEM14C,AUP1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,EDEM2,UBR4,TPK1,ARMC4,KPNA3,ADNP,CEBPZ,SRFBP1,NFRKB,USP11,TSPAN5,SMG1,TNIK,SUPT6H,DYM,PDE4B,CLSTN2,ATF7IP,SEMA3E,PPP1R1C,ENOX1,BMP6,MAN1A1,PRKCH,DSG2,TTC17,ERI3,FBL,LDLRAD3,AMOT,DMRT1,KDM6B,DNMBP,FGF2,ZNF821,PPP1R21,SCFD2,MARS,PHACTR2,PDE2A,LENG8,EIF5B,ZNF407,NAALADL2,SYMPK,RERE,WDR35,AGTPBP1,CUL2,MBD6,MMP16,SLC16A10,ZSWIM6 |
| 3.895e-11 | -23.97 | chromatin organization | biological process | GO:0006325 | 686 | 150 | 16441 | 2138 |
TRIM16,UBN1,KMT2E,ATRX,BCOR,HLTF,SIRT2,PRKCA,SMARCB1,KANSL1,CHD2,KDM5C,POLE3,CARM1,DPF3,CHD9,AEBP2,SETD1B,SIRT6,BAZ2A,CDK4,EHMT1,EYA3,WDHD1,HDAC8,SUPT20H,HIST1H2BL,KMT2C,MCM2,CHAF1A,DOT1L,PAF1,UBTF,TCF7L1,BRCA2,TRRAP,SUPT4H1,HLCS,CHD3,PER1,BMI1,EMSY,USP15,BANP,WDR75,EP400,TAF1,SIRT7,RSF1,CDC73,CHD5,ARID1B,TOX4,RNF40,MBD2,MYC,VPS72,MED24,CTR9,ANP32B,PRMT5,MAP3K12,MYB,GATAD2B,WDR61,TSPYL4,USP49,PRDM16,JMJD1C,ELP3,ARID5B,SETD2,WBSCR22,SMARCD3,ARID1A,SUPT5H,TRIM37,UBE2E1,NAP1L5,ATXN7,EHMT2,TBL1X,NCOR1,SMYD3,USP7,ASH1L,ARID2,SMARCA4,RING1,KDM1A,CHD7,BRE,KDM2A,WAC,HIRIP3,RNF2,KMT2A,PRMT3,SAP30,KAT8,KDM3B,KMT2D,BRD4,SATB2,SETD7,BAZ1A,SMARCC1,KDM4B,ELP2,MBTD1,H2AFX,BRCC3,BRD9,SETD6,YEATS2,HMGA2,DNAJC2,NCOR2,SUPT6H,TCF3,H2AFJ,JMJD6,ATF7IP,IKBKAP,RPS6KA5,HIST2H2AB,TADA3,SUV39H2,ELP5,HIST2H3D,FBL,TOP1,KDM6B,KDM5B,SMARCAD1,KDM5A,SCMH1,HIST1H4J,MEN1,CENPP,RERE,NSD1,SRCAP,L3MBTL3,SET,ATM,TAF12,KDM4C,IPO4,KAT6A |
| 4.291e-11 | -23.87 | nuclear body | cellular component | GO:0016604 | 343 | 88 | 17570 | 2233 |
USP7,SART1,THOC5,TRIM16,UBN1,KMT2E,ATRX,TFIP11,PLRG1,RCHY1,CCNL2,RPAIN,RING1,SKI,ZC3H13,SRSF2,NEK6,PHF5A,ZFHX3,NSRP1,YLPM1,WAC,RNF2,SRRM2,ZMYM2,LSM10,OGG1,CDK12,CASP8AP2,TIMM50,PRPF19,MAML3,SETD1B,SUMO3,PNN,DKC1,SON,LSG1,SPOP,DDX3X,SKIL,GEMIN5,EIF4ENIF1,NSMCE2,FAM206A,LUC7L3,HIPK2,ARNTL,PQBP1,PRPF4,ZC3H8,NOLC1,MEF2C,NCOR2,EP400,SHQ1,PRPF31,AK6,SF3A3,TRIM22,CSNK1A1,RSRC1,ELL,HR,USPL1,CTR9,ICE2,NOC3L,GEMIN4,FBL,NRIP1,HNRNPM,CLK2,GATAD2B,APEX1,RREB1,WDFY3,PSPC1,TOP3A,PLCB1,NOP58,TCF7L2,RPA1,PRPF40B,TOE1,HIF1A,CDK9,KAT6A |
| 4.761e-11 | -23.77 | ONKEN_UVEAL_MELANOMA_UP | MSigDB lists | ONKEN_UVEAL_MELANOMA_UP | 738 | 157 | 17758 | 2279 |
LETM1,NF1,PTPRA,NAT10,CSPP1,BCOR,PRKCA,UBR5,MAP2K3,PCDH7,RABGAP1L,MAD1L1,ME1,NDUFA6,VPS13B,FLNC,SLC38A6,WLS,PTPRM,ANK2,CUX1,EFHC1,CAMSAP2,COTL1,RBM28,DDX60,DLST,TMCO1,TRRAP,LSM14A,CHD3,LUC7L3,BDH2,AHNAK2,SYNPO,HERC2,CELSR1,EGR1,SEC24D,ZHX3,TRIO,CLINT1,SLC1A1,FKBP1A,UBE3A,ASAP1,PDE10A,MBD2,MAP3K12,CNOT4,NT5E,VOPP1,FADS1,PEA15,PDE4A,LAMC1,TSTA3,RB1CC1,POLA1,TRA2A,ELOVL6,RAPGEF4,JMJD1C,AGAP1,MTR,ISG15,RDH11,MGAT2,SYNCRIP,PDLIM1,HK2,PTRH2,SQLE,KIAA0196,NCOR1,MACROD1,IFITM2,TCF12,ZNF706,NPAS2,RBFOX2,C16orf45,KIAA0232,ACTR3,GPR143,SMARCA4,GRINA,SAFB2,URB1,STAM,CHD7,DECR1,RRN3,SHC1,TTC3,MET,CASP8AP2,AUP1,SAP30,PCGF3,PCMT1,LGALS1,AKAP13,TBC1D16,NUDT15,TTC28,RAD54B,WARS,BAZ1A,TAF2,HLA-DMA,SMAD3,CDC16,ASTN2,COPS5,ABHD3,H2AFX,HSPB8,PAM,TRAF3,LAMA5,MORC2,DNAJC2,SERINC5,MINK1,AUH,RCAN1,TRIM22,PHLDA2,SFI1,MFSD10,PTPN2,SNW1,SACS,RDX,PTGS1,ARHGAP1,GREB1,EXOSC4,SAMD4A,HSD17B12,SPTAN1,FGF9,PSPC1,NXN,RAP1GDS1,PTK2,PPIP5K2,C8orf33,UBE2K,SLC23A2,ALG5,ZDHHC11,PXDN,BAZ2B,ATM,PSAP |
| 5.238e-11 | -23.67 | stomach-carcinoma-adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-adenocarcinoma | 15944 | 2127 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SGSM3,PAFAH1B1,C16orf45,VTI1A,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,SREBF2,SYN2,PDS5B,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,HARS,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,ZNF589,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RNF111,ME1,SEH1L,TBC1D8,DDN,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,LRRIQ1,ABCF2,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,RASSF3,RABGAP1L,FAAH2,WIZ,FNIP2,ZNF148,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,SF3A3,JMJD6,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PRDM1,ZSCAN16-AS1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 5.316e-11 | -23.66 | ncRNA processing | biological process | GO:0034470 | 316 | 84 | 16441 | 2138 |
SART1,LIN28B,AARS2,LAGE3,POP5,NUP43,NUP160,AARS,SBDS,NOP56,RPP30,METTL16,CHD7,RPS16,PUS3,MPHOSPH10,DUS4L,ERI1,NUP133,TRMU,INTS12,RAN,TRMT10A,TRMT12,UTP4,FTSJ3,SEH1L,METTL1,WDR36,SKIV2L2,NPM3,NOL8,METTL2A,NOL6,METTL15,DKC1,NUP214,PUSL1,PES1,SMAD3,RANBP2,DUS3L,TRMT5,INTS9,FTSJ1,SRFBP1,PUS1,HEATR1,TSEN2,PDCD11,NOLC1,METTL2B,CTU2,SARS,DROSHA,UTP14A,AGO2,HSD17B10,FARS2,POM121,MRPS11,DDX56,TRMT13,INTS7,ALKBH8,EXOSC4,GEMIN4,ERI3,FBL,CPSF3L,DIS3L2,EXOSC2,ELP3,TYW1,WBSCR22,UTP15,NOP58,POP1,EPRS,ZBTB8OS,INTS5,ADAT2,CDKAL1,AGO3 |
| 5.483e-11 | -23.63 | macromolecule biosynthetic process | biological process | GO:0009059 | 3697 | 600 | 16441 | 2138 |
ASCC1,AARS2,MRPL10,HLTF,CCNL2,ZNF44,NUP160,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,ZNF148,KDM5C,ZNRD1,HMBOX1,EIF4E3,RNMT,NFIA,RFX2,C5AR1,MCM2,ZNF197,DDX3X,ZNF266,BRCA2,SUPT4H1,RAD18,RUNX1,ZNF532,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,YARS2,EIF2S2,MCM5,ZNF326,MED24,MRPL21,PRMT5,ZNF518B,AGL,PABPC1,PPA1,MYB,ZNF675,GATAD2B,GTF2H3,ALG6,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,SMARCD3,ST6GALNAC3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,RPL28,CDK9,CCDC85B,ZNF160,CNOT6,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,NUP43,ST3GAL6,SAFB2,MCM9,ZKSCAN1,WAC,ATRIP,LSM10,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,MEF2D,SLC35D1,FGFR1,TAF2,KDM4B,ELP2,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,TRAK1,ID2,JMJD6,TRIM22,BHLHE40,POM121,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,RPL22L1,SOX6,POLK,MRPS10,ZNF467,FOXC1,UBC,MRPL36,RPA1,TRIB3,NSD1,SRCAP,RARS,BAZ2B,POLE2,ARID3B,SRD5A3,KDM4C,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,SEC16A,BIRC2,SRSF2,PHF5A,HKR1,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,CHD9,ZNF124,ATF4,AEBP2,GCNT2,PPARG,HARS,BAZ2A,ZNF414,MED27,ATG12,BRCA1,ZNF91,MLLT10,GLS,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,DLX2,BEND6,SARS,MCM6,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,TRAPPC9,PAXBP1,TLE3,SETD2,TRAPPC6B,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,TBPL1,ZNF430,DTD1,NAPA,MPI,ID1,ARID2,RPS29,ZNF83,ZNF709,TNKS1BP1,PELP1,ZNF121,RPAIN,KDM1A,DENR,NRF1,ZBTB21,NUP133,ZDHHC6,ETF1,ZFP37,RNF2,SEC24A,KAT8,KDM3B,PCGF3,NARS,NUP214,ZNF251,EIF3H,SMAD3,RANBP2,SIX5,ZNF333,KLF4,ATG7,ZNF436,MED20,ZNF18,EIF2B3,ZNF507,NIFK,MCM10,RFX1,AGO2,VARS,FOXP1,RMI1,ZNF594,ZNF561,SELT,POLR1B,SNAPC5,TRNP1,GINS3,FOXN3,ZNF654,ZMYM5,NEU1,POLR3A,ZRANB3,POLR3G,GPC2,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,POLB,CUL4A,PRKCSH,PRKAB2,GYG1,GABPB2,AARS,MGA,LPIN1,RPS16,RNF111,CHD2,MEIS3,FUT11,SEH1L,CSGALNACT2,ZNF646,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,ZDHHC14,DENND4A,SAP30BP,GZF1,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,LARS2,ZHX3,ST6GAL1,GTF2IRD1,DPM3,SSR4,CHD5,IGF2BP3,HR,ENTPD5,ZNF586,SCAF1,MYC,PIGG,GTF3C3,TERF2,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,SEC31A,ZNF425,ASCC3,EPRS,NSF,HIF1A,SRP68,SPEN,VCAN,ZBTB12,MED15,PURB,NCOR1,ZFHX2,HS2ST1,ZNF254,ZBTB37,FOSL2,RING1,TERF2IP,CHD7,ZNF827,SLX4,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,SERPINH1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,SERP1,ZBTB25,BAZ1A,VDR,DNTTIP1,MSX2,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,LARGE,TROVE2,NCOR2,C10orf2,B4GALT5,TCF3,ZNF280C,NFX1,FARS2,MYNN,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,HARS2,YBX3,NT5M,FAM120B,TSHZ1,TTLL5,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,ZDHHC11,ORC5,DDIT3,KAT6A,ZNF76,PIGM,PHF3,EIF3C,KMT2E,ATRX,RARS2,RCHY1,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,MRPS30,SRPRB,CNIH3,YLPM1,JAZF1,HYAL1,ZEB1,RELB,POLR3B,SLC35C2,YARS,GALNT18,CARM1,TRIP13,ELOF1,ZBTB17,DEAF1,SESN2,TXLNG,ZNF195,ZNF680,SIRT6,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,ST3GAL5,TAF9B,CHAF1A,UBTF,PAF1,GATA6,CC2D1B,MKL2,CTAGE5,PQBP1,CRCP,GALNT10,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,CHST11,PIGN,TAF1,SEC24D,PAX2,DPF2,ALG8,MED13L,DDIT4,ELL,ZNF354A,ISPD,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,LIG4,PRDM1,EIF2A,TMEM241,ISG15,MGAT2,MYBBP1A,RRAGA,CDKAL1,ZFP90,TBL1X,NR2C2AP,ZBTB24,TCF12,ASH1L,CEMIP,PIGH,PBX1,SMARCA4,ZSCAN5A,FARSA,RRN3,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,MAML3,NARS2,PRAME,TFCP2,PARP2,SFSWAP,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,WARS,BATF3,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,DBF4,PPHLN1,ATF7IP,MED18,GFM2,MAN1A1,MRPS11,HAS3,SEC24C,DMRT1,PKNOX1,RPS6KB2,TOP1,ARNTL2,MSX1,KDM5B,ZNF821,TEAD1,KDM5A,PSPC1,ZNF324B,SCMH1,MARS,MEN1,ZNF407,EIF5B,TARS,ZNF221,RERE,ZNF708,ALG5,NCBP2,POLR1C,NFKBIB |
| 5.525e-11 | -23.62 | cellular macromolecule biosynthetic process | biological process | GO:0034645 | 3619 | 589 | 16441 | 2138 |
ASCC1,AARS2,MRPL10,HLTF,CCNL2,ZNF44,PABPC4,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,ZNF148,KDM5C,ZNRD1,HMBOX1,EIF4E3,RNMT,NFIA,RFX2,C5AR1,MCM2,ZNF197,DDX3X,ZNF266,BRCA2,SUPT4H1,RAD18,RUNX1,ZNF532,MEF2C,CARS,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,YARS2,EIF2S2,MCM5,ZNF326,MED24,MRPL21,PRMT5,ZNF518B,AGL,PABPC1,PPA1,MYB,ZNF675,GATAD2B,GTF2H3,ALG6,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,USP10,SMARCD3,ST6GALNAC3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,GTF2A1,RPL28,CDK9,CCDC85B,ZNF160,CNOT6,SRP14,ZNF516,TRERF1,GTF2H2C,NPAS2,ST3GAL6,SAFB2,MCM9,ZKSCAN1,WAC,ATRIP,LSM10,KMT2D,GARS,ZNF480,EIF3J,NPM3,ATF7IP2,MEF2D,SLC35D1,FGFR1,TAF2,KDM4B,ELP2,HIPK2,POLR3E,HOXA3,ZBTB11,COMMD10,HMGA2,ZNF786,TRAK1,ID2,JMJD6,TRIM22,BHLHE40,TADA3,SNW1,POLR3D,GATC,SUV39H2,TAF3,ZNF710,RPL22L1,SOX6,POLK,MRPS10,ZNF467,FOXC1,UBC,MRPL36,RPA1,TRIB3,NSD1,SRCAP,RARS,BAZ2B,POLE2,ARID3B,SRD5A3,KDM4C,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,SEC16A,BIRC2,SRSF2,PHF5A,HKR1,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,CHD9,ZNF124,ATF4,AEBP2,GCNT2,PPARG,HARS,BAZ2A,ZNF414,MED27,ATG12,BRCA1,ZNF91,MLLT10,GLS,TCF7L1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,DLX2,BEND6,SARS,MCM6,FOXO1,LAMTOR3,SMAD7,HES6,BARX2,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,WARS2,TRAPPC9,PAXBP1,TLE3,SETD2,TRAPPC6B,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,TBPL1,ZNF430,DTD1,NAPA,MPI,ID1,ARID2,RPS29,ZNF83,ZNF709,TNKS1BP1,PELP1,ZNF121,RPAIN,KDM1A,DENR,NRF1,ZBTB21,ZDHHC6,ETF1,ZFP37,RNF2,SEC24A,KAT8,KDM3B,PCGF3,NARS,ZNF251,EIF3H,SMAD3,SIX5,ZNF333,KLF4,ATG7,ZNF436,MED20,ZNF18,EIF2B3,ZNF507,NIFK,MCM10,RFX1,AGO2,VARS,FOXP1,RMI1,ZNF594,ZNF561,SELT,POLR1B,SNAPC5,TRNP1,GINS3,ZNF654,FOXN3,ZMYM5,NEU1,POLR3A,ZRANB3,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,POLB,CUL4A,PRKCSH,PRKAB2,GYG1,GABPB2,AARS,MGA,LPIN1,RPS16,RNF111,CHD2,MEIS3,FUT11,CSGALNACT2,ZNF646,DPF3,SETD1B,NR6A1,NOL8,EYA3,CUX1,TCEB3,ZDHHC14,DENND4A,SAP30BP,GZF1,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,PTPN14,IFT57,EGR1,LARS2,ZHX3,ST6GAL1,GTF2IRD1,DPM3,SSR4,CHD5,IGF2BP3,HR,ENTPD5,ZNF586,SCAF1,MYC,PIGG,GTF3C3,TERF2,RREB1,PRIM2,POLA1,ARID1A,NELFA,ZNF850,PHF6,SEC31A,ZNF425,ASCC3,EPRS,NSF,HIF1A,SRP68,SPEN,VCAN,ZBTB12,MED15,PURB,NCOR1,ZFHX2,HS2ST1,ZNF254,ZBTB37,FOSL2,RING1,TERF2IP,CHD7,ZNF827,SLX4,KDM2A,UCHL5,LPIN2,MRPS27,SSBP1,KMT2A,CASP8AP2,SAP30,RFC4,BRD4,RFC3,MTIF2,SATB2,MED16,PNN,SETD7,POLG2,SERP1,ZBTB25,BAZ1A,VDR,DNTTIP1,MSX2,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,FTSJ1,LARGE,TROVE2,NCOR2,C10orf2,B4GALT5,TCF3,ZNF280C,NFX1,FARS2,MYNN,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF239,ZNF483,COMMD9,PTRF,ELP5,HARS2,YBX3,NT5M,FAM120B,TSHZ1,TTLL5,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,ZDHHC11,ORC5,DDIT3,KAT6A,ZNF76,PIGM,PHF3,EIF3C,KMT2E,ATRX,RARS2,RCHY1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,MRPS30,SRPRB,CNIH3,YLPM1,JAZF1,ZEB1,RELB,POLR3B,SLC35C2,YARS,GALNT18,CARM1,TRIP13,ELOF1,ZBTB17,DEAF1,SESN2,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,ZSCAN2,SOX4,KMT2C,ST3GAL5,TAF9B,CHAF1A,UBTF,PAF1,GATA6,CC2D1B,MKL2,CTAGE5,PQBP1,CRCP,GALNT10,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,CHST11,PIGN,TAF1,SEC24D,PAX2,DPF2,ALG8,MED13L,DDIT4,ELL,ZNF354A,ISPD,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,LIG4,PRDM1,EIF2A,TMEM241,ISG15,MGAT2,MYBBP1A,RRAGA,CDKAL1,ZFP90,TBL1X,NR2C2AP,ZBTB24,TCF12,ASH1L,PIGH,PBX1,SMARCA4,ZSCAN5A,FARSA,RRN3,CAMTA2,ZNF142,FHIT,CPSF3,ZNF460,UTP4,MAML3,NARS2,PRAME,TFCP2,PARP2,SFSWAP,GRHL3,MRRF,POU2F1,ATXN1,DKC1,EDEM2,WARS,BATF3,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,BRD9,DNAJC2,SUPT6H,DBF4,PPHLN1,ATF7IP,MED18,GFM2,MAN1A1,MRPS11,HAS3,SEC24C,DMRT1,PKNOX1,RPS6KB2,TOP1,ARNTL2,MSX1,KDM5B,ZNF821,TEAD1,KDM5A,PSPC1,ZNF324B,SCMH1,MARS,MEN1,ZNF407,EIF5B,TARS,ZNF221,RERE,ZNF708,ALG5,NCBP2,POLR1C,NFKBIB |
| 5.542e-11 | -23.62 | chromatin modification | biological process | GO:0016568 | 543 | 125 | 16441 | 2138 |
USP7,ASH1L,TRIM16,UBN1,ARID2,KMT2E,ATRX,SMARCA4,BCOR,HLTF,SIRT2,PRKCA,RING1,KDM1A,SMARCB1,CHD7,BRE,KDM2A,KANSL1,WAC,CHD2,RNF2,KDM5C,POLE3,KMT2A,PRMT3,CARM1,KDM3B,KAT8,DPF3,CHD9,BRD4,AEBP2,KMT2D,SETD1B,SIRT6,BAZ2A,EHMT1,EYA3,HDAC8,SATB2,SETD7,KMT2C,DOT1L,PAF1,BAZ1A,UBTF,BRCA2,TRRAP,SUPT4H1,SMARCC1,KDM4B,HLCS,CHD3,PER1,MBTD1,BRCC3,SETD6,BMI1,BRD9,YEATS2,EMSY,USP15,BANP,HMGA2,DNAJC2,WDR75,EP400,TAF1,SUPT6H,TCF3,SIRT7,JMJD6,RSF1,RPS6KA5,CDC73,CHD5,ARID1B,TOX4,RNF40,TADA3,SUV39H2,MBD2,MYC,VPS72,MED24,CTR9,PRMT5,FBL,MAP3K12,MYB,TOP1,KDM6B,GATAD2B,KDM5B,WDR61,USP49,SMARCAD1,KDM5A,JMJD1C,ELP3,SETD2,WBSCR22,SMARCD3,SCMH1,ARID1A,HIST1H4J,MEN1,SUPT5H,TRIM37,UBE2E1,RERE,CENPP,NSD1,ATXN7,SRCAP,EHMT2,L3MBTL3,ATM,TAF12,NCOR1,TBL1X,SMYD3,KDM4C,KAT6A |
| 5.620e-11 | -23.60 | BIOPOLYMER_METABOLIC_PROCESS | MSigDB lists | BIOPOLYMER_METABOLIC_PROCESS | 1660 | 301 | 17758 | 2279 |
POLB,UBR5,AARS,GABPB2,PABPC4,NEK6,SREBF2,ZFHX3,ZNF148,CHD2,CSGALNACT2,NR6A1,RNMT,PTPRM,NOL8,EHMT1,TCEB3,CUX1,MCM2,SPOP,SKIL,BRCA2,SUPT4H1,CCNT1,LUC7L3,RUNX1,PTPN14,ZHX3,PRPF31,KHDRBS1,DPM3,RSF1,PARN,IGF2BP3,PRKCE,UBE3A,INTS7,MCM5,MYC,PIGG,MED24,GEMIN4,PRMT5,CCDC88C,MAP3K12,PABPC1,TERF2,USE1,SCAF11,SIK3,EXOSC2,PRIM2,RREB1,ALG6,POLA1,ARID5B,PTPN12,SMARCD3,ARID1A,KPNA1,HIF1A,CDK9,NCOR1,ZNF254,TRERF1,NPAS2,FOSL2,ST3GAL6,HSPA1A,NOP56,TERF2IP,PRKD3,BCAS2,ACD,INTS12,MSH4,PXK,CDK12,RFC4,PMS1,RFC3,KRT7,PCMT1,MED16,POLG2,DSP,STK10,ERC1,SERP1,TAF2,ELP2,SMARCC1,PAM,LARGE,ALKBH1,NOLC1,XRCC4,TROVE2,HMGA2,SSH2,BRAF,XPC,TCF3,TRAK1,NFX1,SF3A3,FARS2,MLH1,TRIM22,IKBKAP,NOL3,RPS6KA5,FOXO3,TADA3,ABL1,SNW1,PTRF,UPF2,CELF1,NT5M,APEX1,POLK,APTX,UBE2K,NOP58,RPA1,ANXA1,OXSR1,RARS,SRCAP,NSD1,POLE2,HNRNPH3,ORC5,PTPN4,ATM,BMP4,ANAPC4,DDIT3,STK4,KAT6A,ZNF76,ATRX,UBN1,PPARGC1B,CSNK2A1,BCOR,SIRT2,SNAPC4,MAP2K3,SMARCB1,ABL2,SRSF2,PHF5A,ATG3,JAZF1,ANAPC11,XRCC2,ANAPC10,ZEB1,RAN,POLE3,HCFC2,YARS,ETV1,OGG1,PRKACB,TRIP13,CARM1,TIMM50,SRPK2,SF3A1,METTL1,TNK2,DEAF1,ATF4,PPARG,SIRT6,TSN,MED27,GMFB,COL4A3BP,ATG12,HDAC8,BRCA1,UBTF,GEMIN5,DYRK1B,MSRA,GATA6,SUFU,CHD3,MKL2,PQBP1,TNFRSF1A,RAD51B,SARS,TTN,FOXO1,TAF1,PAX2,PRSS3,ALG8,SMG7,EVPL,SUB1,ELL,ZNF354A,VPS72,BUD31,GTF2H1,NRIP1,POLR1E,CPSF3L,NT5E,CAMKK2,TRA2A,ELP3,JMJD1C,LIG4,MEX3B,PRDM1,SUPT5H,ISG15,TCF7L2,UBE2E1,POP1,MYBBP1A,BICD1,SYNCRIP,INTS5,IRAK2,BRSK2,TCF12,USP7,ASH1L,RBFOX2,PIGH,PBX1,PPP2R2A,CSTA,RPAIN,RRN3,NRF1,SOCS1,CPSF3,MAML3,KAT8,TFCP2,PARP2,SFSWAP,DKC1,WARS,RAD54B,BATF3,EXO1,SMAD3,RBBP8,HNRNPR,COPS5,KLF4,ARNTL,CEBPZ,ATG7,INTS9,MED20,NFRKB,MUTYH,SMG1,MINK1,AUH,MAP3K13,CAMK1,DBF4,ATF7IP,ZNF346,CSNK1A1,BMP6,PRKCH,PTPN2,FBL,SNAPC5,KDM5B,SMARCAD1,FOXN3,KDM5A,MEN1,HSPA1B,POLR3G,ALG5,GADD45A,TBX3,SET,MSH3,FNTB,NCBP2,ZRANB2,RBPJ,NR2F2,POLR1C,ZAK |
| 5.929e-11 | -23.55 | glioma | COSMIC cancer mutations | glioma | 16917 | 2225 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RASSF3,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 6.287e-11 | -23.49 | aromatic compound biosynthetic process | biological process | GO:0019438 | 3030 | 505 | 16441 | 2138 |
ZNF292,POLB,MYCBP2,ASCC1,CUL4A,PRKAB2,HLTF,CCNL2,ZNF44,NUP160,GABPB2,LPIN1,MGA,SKI,ZNF37A,RPS16,SREBF2,IKZF5,ZFHX3,ATP5G2,RNF111,ME1,ZNF148,CHD2,KDM5C,MEIS3,ZNRD1,FXN,SEH1L,ZNF646,DPF3,HMBOX1,SETD1B,RNMT,NR6A1,UPP1,EYA3,NFIA,TCEB3,CUX1,RFX2,C5AR1,DENND4A,SAP30BP,ZNF197,STOML2,GZF1,DDX3X,SKIL,ZNF266,TRRAP,SUPT4H1,RAD18,CCNT1,ZNF81,HIC2,RUNX1,BMI1,ZNF532,PTPN14,MEF2C,BANP,IFT57,EGR1,TRIP6,ZHX3,KHDRBS1,SIRT7,GTF2IRD1,RSF1,CDC73,CHD5,HR,ZNF586,SCAF1,MYC,ATIC,ZNF326,MED24,GTF3C3,PRMT5,ZNF518B,PRPS1,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,PRIM2,RREB1,ZNF587,RB1CC1,PRDM16,POLA1,ARID5B,ZNF512B,USP10,SMARCD3,IMPDH2,ARID1A,NELFA,TRIM37,ONECUT2,SRA1,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,ASCC3,MTHFD2,GTF2A1,NME7,RPL28,HIF1A,CDK9,SPEN,MED15,ZBTB12,SURF1,CCDC85B,ZNF160,PURB,UMPS,CNOT6,NCOR1,ZFHX2,ZNF254,ZNF516,TRERF1,GTF2H2C,NPAS2,ZBTB37,UROD,NUP43,FOSL2,SAFB2,RING1,TERF2IP,CHD7,FLAD1,ZNF827,KDM2A,ZKSCAN1,UCHL5,WAC,LPIN2,CMPK1,KMT2A,MTHFD2L,LSM10,CASP8AP2,SAP30,RFC4,RFC3,BRD4,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,SATB2,MED16,MEF2D,PNN,SETD7,SLC35D1,POLG2,MAT2A,FGFR1,SNCA,ZBTB25,VDR,TAF2,BAZ1A,DNTTIP1,MSX2,SMARCC1,KDM4B,ELP2,HIPK2,G6PD,ZNF236,MBTD1,POLR3E,HOXA3,ZBTB11,TROVE2,COMMD10,HMGA2,NCOR2,ZNF786,C10orf2,TCF3,ZNF280C,NFX1,ID2,JMJD6,MYNN,TRIM22,BHLHE40,IKBKAP,TGFB2,FOXO3,MAD2L2,POM121,SFR1,ZNF483,TADA3,ZNF239,SNW1,POLR3D,COMMD9,PTRF,SUV39H2,ELP5,TAF3,YBX3,ZNF710,SOX6,FAM120B,TSHZ1,TTLL5,PSAT1,APEX1,POLK,ADSL,ZNF467,KLF6,MMAA,FOXC1,UBC,POLR2A,RPA1,ZFP62,TRIB3,NSD1,SRCAP,BAZ2B,ZNF155,POLE2,ARID3B,ADK,DDIT3,KDM4C,KAT6A,ZNF76,PHF3,GPBP1L1,ATRX,KMT2E,PPARGC1B,POLR1A,RCHY1,CSNK2A1,ZNF107,BCOR,SIRT2,COX10,SNAPC4,BIRC2,SMARCB1,AMPD3,SRSF2,PHF5A,YLPM1,JAZF1,HKR1,PPCDC,RELB,ZEB1,POLR3B,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,SESN2,ZNF124,TXLNG,ZNF195,PPARG,ZNF680,ZNF414,BAZ2A,MED27,MINA,HDAC8,MTHFD1L,BRCA1,KMT2C,SOX4,ZSCAN2,ZNF91,MLLT10,TAF9B,PAF1,GLS,UBTF,HPRT1,TCF7L1,GATA6,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,PQBP1,CRCP,DLX2,ZC3H8,ZNF397,BEND6,NOCT,DMTF1,EMSY,SARS,AK2,FOXO1,TAF1,PAX2,DPF2,LAMTOR3,SMAD7,HES6,MED13L,BARX2,ZIC2,RLF,ARID1B,NAMPT,DDIT4,ELL,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,GMDS,NRIP1,POLR1E,NT5E,MTHFD1,ZNF629,VOPP1,ZNF234,PAXBP1,TSTA3,PPAT,TLE3,JMJD1C,ELP3,SETD2,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,SUPT5H,ISG15,TCF7L2,NR2F1,PWP1,ATXN7,MYBBP1A,RRAGA,TBPL1,ZNF430,ZFP90,HMBS,TBL1X,ZBTB24,NR2C2AP,TCF12,MPI,ID1,ASH1L,SUCLG1,ARID2,RPS29,SMARCA4,PBX1,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,ZSCAN5A,CAD,RRN3,NRF1,ZBTB21,CAMTA2,NUP133,ZNF142,ZFP37,RNF2,FHIT,CPSF3,ZNF460,UTP4,TMEM14C,MAML3,KAT8,KDM3B,PCGF3,PRAME,TFCP2,SFSWAP,CPOX,GRHL3,ATXN1,POU2F1,NUP214,ZNF251,ATP5D,TPK1,BATF3,SMAD3,RANBP2,ALAD,IKZF4,ADNP,SIX5,COPS5,ZNF557,KLF4,ZNF333,ARNTL,CEBPZ,ATG7,ZNF436,SRFBP1,NFRKB,MED20,ZNF18,BRD9,ZNF507,DNAJC2,NIFK,SUPT6H,RFX1,AGO2,PPHLN1,APRT,MED18,ATF7IP,CHCHD10,FOXP1,ZNF594,GART,ZNF561,POLR1B,DMRT1,PKNOX1,SNAPC5,ARNTL2,MSX1,TRNP1,KDM5B,ZNF821,TEAD1,ZNF654,PSPC1,FOXN3,KDM5A,ZMYM5,SCMH1,ZNF324B,MEN1,ZNF407,POLR3A,RERE,ZNF221,POLR3G,ZNF708,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,NCBP2,ZNF32,MYRF,RBPJ,TAF12,POLR1C,NFKBIB,NR2F2 |
| 6.571e-11 | -23.45 | prostate | COSMIC cancer mutations | prostate | 14584 | 1976 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,SLC25A26,ZNF532,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,UBL5,RPGRIP1L,CD96,ESAM,SPG21,ZSWIM7,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,FAM171A2,PCNXL2,MEF2D,KCNH3,SLC35D1,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,RPS6KB1,CEP170,METTL2B,CATSPERG,MAPT,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,SPTAN1,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,SUMO3,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,C1orf122,BSN,TCF7L1,LSS,INSIG1,CHD3,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,ARID1B,SPIRE1,SUB1,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,SART1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,RAB7A,ANKRD33B,CA5B,NHSL1,EIF3H,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,HM13,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,POGZ,SLC25A20,ADH5,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,LRRIQ1,MON1A,FOXN3,SMARCAD1,C22orf34,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,RBPJ,TAF12,NR2F2,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,PDCD5,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,PHF6,ATP9B,CAT,ASCC3,C6orf141,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,SNCA,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,AGPAT4,ADSL,PACS1,BMS1,KLF6,GUF1,SLC23A2,RETSAT,DDX50,IREB2,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IMMP2L,ZNF76,LETM1,LYRM4,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,ISPD,CCDC124,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,FNBP1L,TBCK,PDE9A,NR2C2AP,TCF12,DMXL2,CHMP2A,DLL4,FEZ2,TMEM183A,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,PRAME,GRHL3,ATXN1,POU2F1,MRRF,DKC1,EDEM2,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,KLC4,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,SCMH1,PDE2A,EIF5B,TMEM187,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NFKBIB,ZSWIM6,NIT1,GNB3,ASCC1,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,FAAH2,RASSF3,RABGAP1L,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,DCUN1D5,C10orf76,SLC50A1,STOML2,DLEU1,DDX3X,BRCA2,SUPT4H1,ZNF266,TMEM139,FIP1L1,RBP1,LPP,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,INTS7,MCM5,CACNB2,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,PEA15,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,SMARCD3,CPT1A,ONECUT2,MBNL2,EVI5,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,GSTA4,CEP63,TMEM136,MTHFD2L,PERP,GARS,KRT7,STAMBP,NPM3,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,WDR37,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,GATC,PVRL3,ARHGAP1,HNRNPM,SOX6,NUDC,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,MRPS10,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,ETFDH,RARS,TOE1,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,PLPPR2,SLCO5A1,PTPN4,PSAP,GPAM,IGBP1,DOCK6,CORO2B,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,FLNC,CHD9,ZNF124,SLC3A2,ABCC4,HARS,BAZ2A,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,PEX1,KIF16B,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,ITPRIP,MEX3A,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,ATXN7,ITPRIPL1,FAM135A,SPAG9,SYNCRIP,PALB2,DNAH17,PPP1R12B,ZNF430,ARHGAP12,HMBS,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,RSL1D1,PPP2R2A,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,C15orf40,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,SMAD3,RANBP2,RBBP8,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,PRRT3,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,MAP1S,C14orf159,ARFIP2,ZNF346,CSNK1A1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,NDUFV1,SACS,ZNF561,ANXA7,CWC27,IFIT5,PRICKLE2,GREB1,DDX31,SELT,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,GINS3,ZNF654,ZMYM5,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,GPC2,SRBD1,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,AARS,UBR5,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,CEP135,MEIS3,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,AOC2,KIAA0586,TTYH2,PTPN12,RABAC1,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,PMEPA1,SRRD,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,PURB,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,RTTN,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,ZBTB37,URB2,RIBC2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,GALK2,MED16,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,HTR7,YIPF2,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,TROVE2,NCOR2,CA11,UTP14A,TTC27,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,NEDD4,MAD2L2,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,PFKFB4,WDFY3,C19orf43,FZD3,KCNMA1,TBRG4,APTX,OASL,NOP58,ECH1,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,TRIP13,TIMM50,LAMA4,ZBTB17,GPM6A,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,DNAJC1,RLTPR,MKL2,BBIP1,ABCC3,GALNT10,ZNF397,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BANF1,BUD31,CCDC112,SEMA3D,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,PDE4A,TSTA3,WBSCR22,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,EP400NL,SDCCAG8,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C7orf26,ZBTB24,ASH1L,PCNT,MMRN2,CELSR3,SLC5A5,MYO7A,ST7L,CSTA,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,DBF4,H2AFJ,NSUN6,CLSTN2,PPHLN1,CCDC7,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,TTC17,DMRT1,MSX1,TEAD1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10 |
| 7.245e-11 | -23.35 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 17176 | 2248 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,IGF2BP2,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 8.691e-11 | -23.17 | INTRACELLULAR_ORGANELLE_PART | MSigDB lists | INTRACELLULAR_ORGANELLE_PART | 1169 | 225 | 17758 | 2279 |
POLB,ATRX,TFIP11,KIF5A,PPARGC1B,MRPL10,TUBE1,SIRT2,NUP160,SNAPC4,GIT2,SMARCB1,RTN1,SRSF2,PHF5A,NSRP1,ATP5G2,JAZF1,ANAPC11,ZNF148,RAN,NDUFA6,OGG1,SPAG6,TIMM50,SF3A1,TMPO,ABCC4,NR6A1,LIMA1,GNL3,NOL8,AP4B1,NOL6,KIF15,WDHD1,SUMO3,MCL1,HDAC8,EFHC1,CAV1,BRCA1,KRTCAP2,MCM2,CHAF1A,PEX1,ARPC3,TIMM44,GEMIN5,UBTF,TRRAP,BRCA2,TP53BP1,CCNT1,MPV17,FIS1,TPM1,DCTN3,TNNC1,TTN,PRPF31,TAF1,HES6,PCSK7,DPM3,RSF1,PDCD7,XPO7,TIMM10,ARID1B,NDUFS7,ETFB,DOPEY1,SUB1,DDX56,INTS7,CEP290,ATXN2,TIMELESS,GTF2H1,VAPB,GTF3C3,GEMIN4,TOMM34,POLR1E,CPSF3L,TERF2,NOM1,HMGCR,SCAF11,TIMM8B,POLA1,ELP3,BCS1L,SMARCD3,LIG4,ARID1A,HERPUD1,POP1,MYBBP1A,KPNA1,HIF1A,INTS5,CDK9,SRP68,LEMD3,SURF1,PURB,PEX13,DHCR7,COG5,PAFAH1B1,NPAS2,ACTR3,MYO7A,MYH9,SMARCA4,RPAIN,RPGRIP1L,NOP56,TERF2IP,RPP30,MPHOSPH10,SPG21,BRE,BCAS2,ACD,NUP133,NBEA,INTS12,CORO1A,CEP63,CPSF3,HTRA2,SAP30,MALL,RFC4,RFC3,ATXN1,VIM,MED16,PNN,DKC1,NUP214,POLG2,ATP5D,TAF2,TAMM41,RANBP2,CDC16,SMARCC1,KPNA3,ELP2,HNRNPR,TIMM17A,HIPK2,DNAJA3,ARNTL,LARGE,PAM,INTS9,SLC25A11,BRCC3,NOLC1,XRCC4,AP2S1,MID1,MAPT,RAB30,BCKDK,VPS45,MAP1S,SF3A3,KIF5C,RTN4,MED18,ZNF346,OPA1,NOL3,IKBKAP,MRPS11,ABL1,SNW1,NDUFV1,SUV39H2,DCTN4,PMPCA,AMOT,PNMA1,HNRNPM,SLC25A1,TOP1,SPTAN1,PPP1R9B,PXN,DDX24,ZFYVE1,KDM5A,ABCF2,TPM4,MRPS10,RANGAP1,APTX,OASL,PALLD,MEN1,RHOT2,SYMPK,NOP58,FOXC1,POLR2A,RPA1,POLR3G,MFN2,RETSAT,SERINC1,ZNF330,TAF4,MSH3,GLG1,TAF12,RBPJ,POLR1C,KIF1B,ANAPC4 |
| 9.079e-11 | -23.12 | NUCLEAR_PART | MSigDB lists | NUCLEAR_PART | 565 | 127 | 17758 | 2279 |
NPAS2,ATRX,TFIP11,PPARGC1B,SMARCA4,NUP160,SNAPC4,RPAIN,GIT2,NOP56,SMARCB1,TERF2IP,RPP30,MPHOSPH10,SRSF2,BRE,BCAS2,PHF5A,ACD,NSRP1,NUP133,JAZF1,ANAPC11,INTS12,ZNF148,CPSF3,OGG1,TIMM50,SF3A1,TMPO,SAP30,NR6A1,GNL3,NOL8,NOL6,WDHD1,ATXN1,HDAC8,MED16,BRCA1,DKC1,NUP214,CHAF1A,GEMIN5,TAF2,UBTF,RANBP2,TRRAP,SMARCC1,ELP2,KPNA3,TP53BP1,HNRNPR,CCNT1,HIPK2,ARNTL,INTS9,PAM,BRCC3,NOLC1,XRCC4,TTN,PRPF31,TAF1,HES6,SF3A3,RTN4,MED18,RSF1,ZNF346,NOL3,IKBKAP,XPO7,PDCD7,ARID1B,ABL1,SNW1,SUB1,DDX56,INTS7,TIMELESS,GTF2H1,GTF3C3,GEMIN4,PNMA1,POLR1E,HNRNPM,CPSF3L,TOP1,NOM1,SCAF11,PPP1R9B,DDX24,POLA1,KDM5A,ELP3,SMARCD3,LIG4,RANGAP1,ARID1A,APTX,OASL,MEN1,SYMPK,NOP58,FOXC1,POLR2A,RPA1,POLR3G,POP1,RETSAT,KPNA1,MYBBP1A,HIF1A,ZNF330,INTS5,CDK9,LEMD3,SRP68,TAF4,MSH3,PURB,RBPJ,TAF12,POLR1C,DHCR7,ANAPC4 |
| 9.495e-11 | -23.08 | cellular response to stress | biological process | GO:0033554 | 1642 | 300 | 16441 | 2138 |
POLB,ASCC1,CUL4A,TMEM109,CHAC1,HLTF,NUP160,UBR5,AARS,AMBRA1,NEK6,SREBF2,PMAIP1,RNF111,FNIP2,CHD2,FXN,SEH1L,DPF3,UPP1,EYA3,MCL1,SHISA5,STOML2,PYCR1,DDX3X,BRCA2,TRRAP,RAD18,NSMCE1,ARL6IP5,MPV17,TPM1,TXN2,ZMAT3,MEF2C,HERC2,EGR1,SLK,PIK3R4,CCDC47,PRKCE,INTS7,APLF,COPS3,MYC,ALKBH8,IGF2BP1,CCDC88C,MAP3K12,TERF2,FADS1,PEA15,GTF2H3,RB1CC1,POLA1,USP10,MTR,SEC31A,ASCC3,ALKBH3,FGFBP1,HIF1A,CDK9,DPEP1,PEX13,MACROD1,WDR33,MAP2K4,MAP2K5,GTF2H2C,NPAS2,PDK4,NUP43,MCM9,HSPA1A,TERF2IP,SLX4,ASNS,SHC1,ZSWIM7,KDM2A,ACD,UCHL5,WAC,ATRIP,MSH4,CEP63,PMS1,RFC4,BRD4,RFC3,PDK1,GNL1,MARCH6,SETD7,POLG2,STK10,SERP1,SNCA,CAMK2D,KDM4B,NSMCE2,HIPK2,G6PD,H2AFX,ALKBH1,BRCC3,XRCC4,BAG1,MAPT,HMGA2,INSIG2,XPC,ID2,ATG2B,GAS6,AKT1S1,MLH1,OPA1,RPS6KA5,GIGYF2,FOXO3,PSMF1,MAD2L2,NEDD4,POM121,SFR1,ABL1,SNW1,NPRL2,SUV39H2,TRIAP1,ANXA5,COPS7B,YBX3,ERRFI1,MAP3K14,MBTPS2,PXN,APEX1,POLK,MRPS10,APTX,UBE2K,KLF6,UBC,POLR2A,ANXA1,RPA1,YIF1A,OXSR1,TRIB3,POLE2,ATM,AEN,APAF1,BMP4,DDIT3,KAT6A,STK4,IMMP2L,CUL7,ATRX,NF1,PPARGC1B,FANCD2,RCHY1,NREP,SIRT2,SLC29A1,MAP2K3,WNT2B,SMARCB1,SRPRB,COPS4,XRCC2,RELB,OGG1,LONP1,TRIP13,PTPRK,CDC37,ZBTB17,TRIM13,ATF4,MIOS,PPARG,SIRT6,HSPA5,COL4A3BP,SUMO3,ATG12,BRCA1,CAV1,SOX4,MGST1,CHAF1A,ZNF622,GATA6,INSIG1,TP53BP1,RAD51B,TNFRSF1A,EME1,COPS6,EMSY,TNRC6A,FBXO45,FOXO1,TAF1,PAX2,CDIP1,FAN1,MAPK8IP3,RHBDD1,DDIT4,CEP164,TIMELESS,VAPB,GTF2H1,WNT16,ATP6V0D1,KRT20,CRADD,SETD2,OBSCN,PSMA1,LIG4,EIF2A,ISG15,TCF7L2,HERPUD1,SPAG9,MYBBP1A,ATAD5,PALB2,IRAK2,HK2,RRAGA,BRSK2,BCCIP,USP7,SLC2A1,RIPK1,RPAIN,BRE,NUP133,DNAJB6,IKBKB,SPIDR,HTRA2,AUP1,CTC1,PRPF19,RTN4RL2,PARP2,EDEM2,NUP214,RAD54B,EXO1,RANBP2,RBBP8,KLF4,COPS5,ARNTL,ATG7,DUSP19,NFRKB,EIF2B3,MUTYH,SMG1,DNAJC2,TNIK,HM13,MCM10,MINK1,SH2D3A,MAP3K13,RMI1,MRPS11,TMEM161A,STC2,FBXO31,KDM6B,SMARCAD1,FOXN3,TOP3A,HIST1H4J,MEN1,CHCHD6,HSPA1B,ZRANB3,GADD45A,CUL2,TBX3,MSH3,EIF2S1,RBPJ,ZAK |
| 1.067e-10 | -22.96 | macromolecular complex subunit organization | biological process | GO:0043933 | 2199 | 383 | 16441 | 2138 |
AARS2,MRPL10,SBF2,ENAH,HLTF,PRKCA,COA1,SYNJ1,SKI,RPS16,NEK6,S100A10,WIZ,ME1,CHD2,KDM5C,SEH1L,ACADS,DPF3,SETD1B,LIMA1,EHMT1,EYA3,WDHD1,SUPT20H,HIST1H2BL,MCM2,FOXRED1,TMSB4X,CLNS1A,STOML2,DOT1L,DDX3X,SKIL,AHNAK,BRCA2,TRRAP,SUPT4H1,LSM14A,LUC7L3,FIS1,BMI1,BANP,WDR75,EP400,CDC42EP2,PRPF31,SIRT7,RSF1,PRPF39,CDC73,CHD5,SLC1A1,NDUFS7,ABCA7,FKBP1A,HR,MYC,MED24,ANP32B,GEMIN4,MRPL21,CCDC88C,PRMT5,MAP3K12,CAV2,MYB,HMGCR,SCAF11,GATAD2B,DDX28,WDR61,TSPYL4,PRDM16,ARID5B,SMARCD3,SNAP25,IMPDH2,ARID1A,CPT1A,TRIM37,ANGPTL4,CAT,SEC31A,DYNC1H1,EPRS,TSR1,EHMT2,RPL28,NSF,SURF1,KIAA0196,NCOR1,SMYD3,VMA21,PAFAH1B1,ACTR3,C1QTNF7,DDR2,MYH9,RING1,BLOC1S2,CHD7,NUBPL,DECR1,KDM2A,PPID,WAC,MRPS27,CEP63,SERPINH1,KMT2A,SAP30,MPP6,KMT2D,BRD4,EIF3J,MTIF2,ASUN,ARHGEF10,PREX1,DLG4,ATP6V0A1,SATB2,SETD7,DSP,TAF2,BAZ1A,HLA-DMA,CAMK2D,SMARCC1,KDM4B,ELP2,DCXR,MBTD1,H2AFX,ANXA2,MDN1,BRCC3,SETD6,YEATS2,HMGA2,NCOR2,SHQ1,BRAF,C10orf2,TCF3,SF3A3,JMJD6,TRIM22,CEP126,MLH1,IKBKAP,NOL3,TGFB2,RPS6KA5,MBNL1,MAD2L2,DCTPP1,TADA3,PSMG4,NEBL,SUV39H2,TMSB10,ELP5,ANXA5,CELF1,ACTR3B,PXN,KCNMA1,MRPS10,ADSL,BMS1,PTK2,UBE2K,FOXC1,MRPL36,SRCAP,NSD1,ATM,NDUFS5,APAF1,UQCC1,IPO4,KDM4C,KAT6A,IMMP2L,TRIM16,EIF3C,UBN1,ATRX,NF1,KMT2E,PPARGC1B,TFIP11,TRPM6,BCOR,SIRT2,COX10,SEC16A,CUTC,BIRC2,EDC3,SMARCB1,MRPS30,ABL2,CNIH3,KANSL1,ZNHIT6,XRCC2,POLE3,RAN,LONP1,CARM1,SF3A1,SRPK2,DBN1,CHD9,AEBP2,SKAP2,SIRT6,BAZ2A,KATNAL1,CDK4,PSMG1,HDAC8,CAV1,KMT2C,MGST1,ARPC3,CHAF1A,GLS,GEMIN5,UBTF,PAF1,HPRT1,TCF7L1,HLCS,CHD3,PER1,TNFRSF1A,RAD51B,CLU,MAGI1,UQCC2,NOCT,EMSY,USP15,TTN,FN1,TAF1,SEC24D,HSD17B10,DNAH1,ARID1B,SPIRE1,DDIT4,TOX4,RNF40,P3H1,ABCA5,MBD2,ATXN2,VPS72,CTR9,PRF1,POLR1E,RANBP6,KRT20,TRAPPC9,LAMC1,USP49,PPAT,ELP3,JMJD1C,SETD2,HAUS6,WBSCR22,BCS1L,EIF2A,TRAPPC6B,SUPT5H,SYT1,UBE2E1,NAP1L5,ATXN7,SPAG9,BICD1,FSCN1,FAT1,SNAP23,TBL1X,NAPA,PDSS2,AGO3,USP7,KCTD7,CHMP2A,SART1,ASH1L,CYLD,PCNT,ARID2,RPS29,SLC2A1,TNXB,SMARCA4,COBLL1,RIPK1,PIBF1,PPP1R9A,SBDS,KDM1A,DENR,KCTD11,BRE,NUP133,DNAJB6,CBR4,CCDC40,HIRIP3,ETF1,RNF2,CORO1A,TMEM120B,PRMT3,PRPF19,SEC24A,KAT8,KDM3B,EVL,COL5A2,PTBP2,C1QTNF1,MRRF,VIM,EIF3H,ARMC4,SMAD3,ALAD,KPNA3,SCARB1,BRD9,AP2S1,PARD3,TMEM33,DNAJC2,NIFK,HM13,KIZ,SUPT6H,AGO2,H2AFJ,ATF7IP,GFM2,HIST2H2AB,POGZ,IQGAP2,MRPS11,SEC24C,HIST2H3D,SHMT2,TTC17,FBL,MICAL3,TOP1,KDM6B,PPP1R9B,KDM5B,SMARCAD1,KDM5A,FERMT2,SCMH1,HIST1H4J,MEN1,CENPP,MKX,RERE,L3MBTL3,SET,NCBP2,NDUFAF5,TAF12 |
| 1.070e-10 | -22.96 | REACTOME_TRNA_AMINOACYLATION | MSigDB lists | REACTOME_TRNA_AMINOACYLATION | 42 | 23 | 17758 | 2279 |
CARS,NARS2,SARS,GARS,WARS2,NARS,HARS,LARS2,RARS2,AARS2,FARS2,MARS,VARS,AARS,TARS,YARS2,WARS,FARSA,EPRS,RARS,HARS2,YARS,PPA1 |
| 1.156e-10 | -22.88 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 16676 | 2201 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,ATF7IP,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.176e-10 | -22.86 | regulation of gene expression | biological process | GO:0010468 | 4171 | 664 | 16441 | 2138 |
ASCC1,THOC5,CHAC1,HLTF,CCNL2,ZNF44,NUP160,NOS1AP,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ZNF148,FNIP2,KDM5C,HRG,ZNRD1,CDK6,HMBOX1,EIF4E3,NRAS,GNL3,EHMT1,NFIA,KRBOX4,RFX2,SLC50A1,ZNF197,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,PARN,CDC73,RBM20,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,SERBP1,MYB,ZNF675,GATAD2B,FADS1,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,MYH9,NUP43,SAFB2,HSPA1A,ERI1,ZKSCAN1,WAC,ZC3H3,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,RPS6KB1,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,RNASEH2B,TGFB2,ZNF691,PSMF1,MBNL1,POM121,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,UQCC1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,BIRC2,HNRNPLL,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CDC37,CHD9,RBCK1,ZNF124,ATF4,AEBP2,GCNT2,PPARG,BAZ2A,ZNF414,CDK4,ANK2,HSPA5,TSN,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,CLK1,NKD2,MAPK8IP3,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,WNT16,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,USP7,ID1,CYLD,UPK3B,ARID2,RBFOX2,RIPK1,ZNF83,SSBP2,ZNF709,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,RNF2,ZFP37,ETF1,AHCYL1,PRMT3,PRPF19,KAT8,KDM3B,PCGF3,DDX41,C1QTNF1,VIM,ENC1,NUP214,ZNF251,PUM3,EIF3H,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,EIF2B3,ZNF589,ZNF507,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ZNF594,ZNF561,ANXA7,HIST2H3D,SELT,POLR1B,CD44,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,HIST1H4J,PIK3CB,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,GLG1,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,PRKCA,GABPB2,AARS,LPIN1,MGA,RNF111,CHD2,MEIS3,SEH1L,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,SON,DENND4A,SAP30BP,SPOP,GZF1,DOT1L,SKIL,TRRAP,CCNT1,LSM14A,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,DROSHA,JUP,EGR1,LARS2,ZHX3,CENPB,PID1,GTF2IRD1,PDCD5,CHD5,IGF2BP3,HR,ZNF586,MYC,IGF2BP1,TERF2,EXOSC2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,ALKBH3,HIF1A,SPEN,MED15,ZBTB12,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,PAIP2,TERF2IP,CHD7,ZNF827,KDM2A,PPID,UCHL5,LPIN2,DTNBP1,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,MTIF2,SATB2,MED16,PNN,SETD7,SERP1,ERC1,ZBTB25,SNCA,VDR,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,ALKBH1,TRAF3,SETD6,NOSTRIN,NCOR2,BRAF,TCF3,ZNF280C,NFX1,RCAN1,MYNN,NOL3,IKBKAP,RPS6KA5,GIGYF2,PHLDA2,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,RDX,CELF1,EXOSC4,YBX3,LARP4B,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,IREB2,ATM,BRWD3,DDIT3,KAT6A,ZNF76,EIF3C,UBN1,NF1,ATRX,KMT2E,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,SLC35C2,HCFC2,OGG1,CARM1,TRIM14,PRKACB,ELOF1,SRPK2,ZBTB17,DEAF1,TRIM13,TXLNG,ZNF195,SIRT6,ZNF680,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,YTHDF2,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,FN1,TAF1,PAX2,DPF2,MED13L,PHGDH,RHBDD1,NAMPT,TOX4,RNF141,ELL,ZNF354A,ATXN2,BUD31,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,XPO5,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,PTRH2,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,SMARCA4,PBX1,ZSCAN5A,RRN3,CAMTA2,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,IGF2BP2,MED18,BMP6,PRKCH,HAS3,STC2,LDLRAD3,DMRT1,PKNOX1,RPS6KB2,TOP1,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,EIF5B,CTIF,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,POLR1C,NFKBIB |
| 1.305e-10 | -22.76 | BRUINS_UVC_RESPONSE_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_LATE | 1078 | 210 | 17758 | 2279 |
IMMP2L,ACTG1,DDX19A,CSNK2A1,GYG1,CCNL2,IKBIP,PRKCA,HMOX2,ABHD6,GIT2,SRPRB,COPS4,PPCDC,IPP,PTPRK,LAMA4,METTL1,FBXW4,CMIP,PTPRM,ATOX1,CUX1,PACRGL,PSMG1,MCL1,CAV1,MCM2,MGST1,CLNS1A,CHAF1A,STOML2,TIMM44,SPOP,PYCR1,CXADR,MLLT10,MSRA,HPRT1,AHNAK,HSDL2,SSU72,PER1,FAM114A2,NSMCE1,TPM1,MTCH1,CHMP4C,TTN,PGPEP1,FN1,STX8,CCDC53,LRRC28,SLK,VTA1,ST6GAL1,TRIM15,CCDC47,TGFBR2,CMTM3,YARS2,FKBP1A,UBE3A,ATIC,MCM5,PPIL2,ZNF326,ANP32B,CCDC88C,TOMM34,ATP6V0D1,ANGPT2,USE1,MSI2,KRT20,SIK3,WARS2,PPAT,POLA1,BCS1L,PSMA1,TRAPPC6B,MBNL2,ANGPTL4,VAC14,ATXN7,UBAP2,MTHFD2,GTF2A1,GSTO2,SRRD,CDK9,RIOK3,SIL1,DPEP1,WDR33,PTP4A2,PRKAR2A,SGSM3,SNX27,RWDD1,CELSR3,SLC48A1,OSBPL9,NTSR1,TMEM183A,PDK4,MYO7A,NUP43,PLEK2,TUBB6,ST3GAL6,PTPRG,LTB4R,RPAIN,FDX1,BLOC1S2,NUBPL,RPP30,IDI1,SHC1,BCAS2,UCHL5,CBR4,C15orf40,SSBP1,AHCYL1,HTRA2,RFC4,ARHGAP17,RFC3,COL5A2,TUBA1A,AKAP8L,PCMT1,TMEM123,CCNDBP1,RAB10,HSD3B7,DCBLD2,BTBD11,DNTTIP1,IQCH,METTL6,G6PD,CAMKMT,ARNTL,H2AFX,ATG7,DUSP19,SLC4A7,DISP1,BRCC3,SETD6,TSPAN5,ECHDC1,PPIL3,COMMD10,HMGA2,DNAJA4,MIF4GD,SHQ1,PDE4B,LIAS,SEMA3E,RSRC1,MAD2L2,NEDD4,MAN1A1,SLC25A20,ADH5,TADA3,COMMD9,RGS17,PEX7,SURF2,CFDP1,PVRL3,TANK,SDCBP2,TTC17,RPL22L1,DNMBP,PSAT1,TMEM126B,TMEM126A,SULT4A1,ADSL,C11orf49,UBE2K,TMEM175,ANXA1,RPA1,RETSAT,PXDN,POLE2,ADAT2,STX18,SRD5A3,RNF138,BCAS3,RBPJ,ITGB4,SORCS2,RABEP1,ARHGAP27,GCSH,STK4,NIT1 |
| 1.313e-10 | -22.75 | ORGANELLE_PART | MSigDB lists | ORGANELLE_PART | 1174 | 225 | 17758 | 2279 |
POLB,ATRX,TFIP11,KIF5A,PPARGC1B,MRPL10,TUBE1,SIRT2,NUP160,SNAPC4,GIT2,SMARCB1,RTN1,SRSF2,PHF5A,NSRP1,ATP5G2,JAZF1,ANAPC11,ZNF148,RAN,NDUFA6,OGG1,SPAG6,TIMM50,SF3A1,TMPO,ABCC4,NR6A1,LIMA1,GNL3,NOL8,AP4B1,NOL6,KIF15,WDHD1,SUMO3,MCL1,HDAC8,EFHC1,CAV1,BRCA1,KRTCAP2,MCM2,CHAF1A,PEX1,ARPC3,TIMM44,GEMIN5,UBTF,TRRAP,BRCA2,TP53BP1,CCNT1,MPV17,FIS1,TPM1,DCTN3,TNNC1,TTN,PRPF31,TAF1,HES6,PCSK7,DPM3,RSF1,PDCD7,XPO7,TIMM10,ARID1B,NDUFS7,ETFB,DOPEY1,SUB1,DDX56,INTS7,CEP290,ATXN2,TIMELESS,GTF2H1,VAPB,GTF3C3,GEMIN4,TOMM34,POLR1E,CPSF3L,TERF2,NOM1,HMGCR,SCAF11,TIMM8B,POLA1,ELP3,BCS1L,SMARCD3,LIG4,ARID1A,HERPUD1,POP1,MYBBP1A,KPNA1,HIF1A,INTS5,CDK9,SRP68,LEMD3,SURF1,PURB,PEX13,DHCR7,COG5,PAFAH1B1,NPAS2,ACTR3,MYO7A,MYH9,SMARCA4,RPAIN,RPGRIP1L,NOP56,TERF2IP,RPP30,MPHOSPH10,SPG21,BRE,BCAS2,ACD,NUP133,NBEA,INTS12,CORO1A,CEP63,CPSF3,HTRA2,SAP30,MALL,RFC4,RFC3,ATXN1,VIM,MED16,PNN,DKC1,NUP214,POLG2,ATP5D,TAF2,TAMM41,RANBP2,CDC16,SMARCC1,KPNA3,ELP2,HNRNPR,TIMM17A,HIPK2,DNAJA3,ARNTL,LARGE,PAM,INTS9,SLC25A11,BRCC3,NOLC1,XRCC4,AP2S1,MID1,MAPT,RAB30,BCKDK,VPS45,MAP1S,SF3A3,KIF5C,RTN4,MED18,ZNF346,OPA1,NOL3,IKBKAP,MRPS11,ABL1,SNW1,NDUFV1,SUV39H2,DCTN4,PMPCA,AMOT,PNMA1,HNRNPM,SLC25A1,TOP1,SPTAN1,PPP1R9B,PXN,DDX24,ZFYVE1,KDM5A,ABCF2,TPM4,MRPS10,RANGAP1,APTX,OASL,PALLD,MEN1,RHOT2,SYMPK,NOP58,FOXC1,POLR2A,RPA1,POLR3G,MFN2,RETSAT,SERINC1,ZNF330,TAF4,MSH3,GLG1,TAF12,RBPJ,POLR1C,KIF1B,ANAPC4 |
| 1.425e-10 | -22.67 | rectum | COSMIC cancer mutations | rectum | 16679 | 2201 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,ATF7IP,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.523e-10 | -22.61 | RNF2 (ring finger protein 2) | protein interactions | 6045 | 699 | 160 | 16036 | 2270 |
THOC5,ACTG1,POLR1A,AARS2,NAT10,RCHY1,CSNK2A1,ADAMTS6,BCOR,SEC16A,MGA,PABPC4,AMBRA1,PHF5A,DHX33,PDS5B,WIZ,KDM5C,RAN,FTSJ3,TRIM14,TIMM50,SF3A1,SNU13,LIMA1,GNL3,NOL6,SON,RBM28,PYCR1,YTHDF2,UBTF,DDX3X,CHD3,LUC7L3,ADAM9,FIP1L1,BMI1,LPP,TTN,ZCCHC8,KHDRBS1,DPF2,CENPB,PHGDH,CLINT1,DDX56,UBE3A,EIF2S2,MCM5,ZNF326,NOC3L,POLR1E,NOM1,MTHFD1,GATAD2B,MSI2,TRA2A,UTP15,SUPT5H,CPT1A,ABCF1,UBE2E1,DYNC1H1,PWP1,EPRS,MYBBP1A,SYNCRIP,RPL28,EHMT2,NSF,SRP68,PURB,SENP3,C7orf50,NAPA,PDLIM5,RNF114,USP7,SART1,DDX18,SMARCA4,RSL1D1,LCLAT1,HNRNPA3,PELP1,EEA1,KDM1A,RING1,FLNB,PHC2,NUBPL,MPHOSPH10,BCAS2,NUP133,VGF,GLYR1,RNF2,PEG10,KMT2A,UTP4,PRPF19,KAT8,WDR36,PCGF3,RFC4,AKAP8L,TFCP2,VIM,DKC1,PUM3,RAB10,PES1,RANBP2,SMARCC1,ADNP,HNRNPR,CEBPZ,H2AFX,SLC25A11,HEATR1,USP11,NOLC1,PDCD11,LRCH1,NIFK,DNAJC2,SF3A3,ZNF346,HIST2H2AB,POGZ,SNW1,RDX,DDX31,YBX3,FBL,HSD17B12,TOP1,PPP1R9B,DDX24,LDHA,SCMH1,BMS1,MARS,RANGAP1,UBE2K,RHOT2,NOP58,TARS,UBC,HSPA1B,RPA1,RARS,DDX50,HNRNPH3,GLG1,EIF2S1,PGAM5,GPATCH4,IPO4 |
| 1.572e-10 | -22.57 | stomach | COSMIC cancer mutations | stomach | 16373 | 2170 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,GRINA,ST3GAL6,LCLAT1,ZMAT2,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RNF111,ME1,SEH1L,TBC1D8,DDN,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,LRRIQ1,ABCF2,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,IGF2BP2,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,RASSF3,RABGAP1L,FAAH2,WIZ,FNIP2,ZNF148,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,SF3A3,JMJD6,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,KTN1-AS1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.716e-10 | -22.49 | GGGCGGR_V$SP1_Q6 | MSigDB lists | GGGCGGR_V$SP1_Q6 | 2787 | 463 | 17758 | 2279 |
ARHGAP26,CGN,POLB,CDCP1,DPH1,PRKAB2,TNFRSF21,SBF2,ENAH,HMOX2,SYNJ1,PABPC4,SREBF2,IKZF5,NSRP1,PDS5B,PRADC1,FUT11,FXN,FTSJ3,PPM1K,ZNF646,DPF3,NRAS,ENHO,EYA3,RFX2,AKAP12,DENND4A,SLC50A1,SLC9A5,SLC7A1,DDAH2,TRRAP,AHNAK,LUC7L3,ARL6IP5,FIS1,BLMH,MEF2C,IFT57,CLDN15,JUP,CDC42EP2,KHDRBS1,DLGAP4,NHS,RSF1,SSR4,KCNJ14,C1orf50,PITPNM1,SLC39A11,IGF2BP3,PRKCE,HR,CNST,EIF2S2,UBE3A,PI4KB,INTS7,MYC,IGF2BP1,CNOT4,PABPC1,SERBP1,ANGPT2,FDFT1,MYB,USE1,BDNF,ALG6,STAG1,ANAPC13,POLA1,PRDM16,EPS15L1,EIF4A2,RAPGEF4,IDH3G,PTPN12,ARRDC4,EHBP1,PLCB1,CPT1A,MTR,DAGLA,DYNC1H1,ASCC3,GTF2A1,NME7,UBAP1,PMEPA1,ZZEF1,SRP68,VCAN,ZBTB12,CCDC85B,PURB,PEX13,MACROD1,SRP14,HS2ST1,SPRED2,TRERF1,SPATA2L,PAFAH1B1,ZBTB37,PDK4,AP1B1,PAIP2,BLOC1S2,ZNF827,ESAM,ASNS,SHC1,KDM2A,UCHL5,VGF,WAC,MMP14,CEP63,CASP8AP2,SAP30,KRT7,NPM3,LGALS1,GNL1,MARCH6,MEF2D,SLC35D1,DSP,ERC1,FKBP3,FGFR1,MAT2A,SNCA,HTR7,ZFAND3,CAMK2D,POLR3E,HOXA3,TRMT2A,RPS6KB1,NOLC1,ZBTB11,TROVE2,LAMA5,ANKS1A,YEATS2,MAPT,BAG1,TMEM141,SSH2,BRAF,XPC,C10orf2,MRI1,RTN4,JMJD6,RCAN1,AKT1S1,IP6K2,BHLHE40,FOXO3,PHLDA2,SFR1,DCTPP1,TADA3,ABL1,RGS17,PTRF,ACOT11,HARS2,UPF2,ARHGAP1,RAPGEFL1,CELF1,ZNF710,FBXL19,SAMD4A,SPTAN1,PFKFB4,TTPAL,SLC40A1,VPS37A,DDX24,C19orf43,KCNMA1,ZC3H18,NXN,ZNF467,UBE2K,ECH1,POLR2A,RPA1,TOE1,ETFDH,DDX50,IREB2,POLE2,STX1A,HERC1,SRD5A3,RNF138,SLCO5A1,BMP4,BRWD3,ADK,STK4,SLC43A1,CYP24A1,IMMP2L,FEM1C,WDR13,PPARGC1B,PTPRA,MFGE8,CSNK2A1,SIRT2,BCOR,MAP2K3,WNT2B,SLC30A7,RTN1,SRSF2,PHF5A,COPS4,PHKA1,ATG3,NCKIPSD,SLC39A7,RELB,JOSD1,KIAA0922,YARS,HCFC2,ZMYM2,SLC25A23,ETV1,OGG1,PRKACB,TRIM14,CDC37,TMPO,SF3A1,ZBTB17,FMNL3,DTNB,SESN2,SKAP2,MIOS,BAZ2A,SIRT6,ZNF414,SLC38A1,HSPA5,VWCE,NOL6,SUMO3,ATG12,BRCA1,MTHFD1L,ZSCAN2,KRTCAP2,KCNH2,SOX4,DLST,ST3GAL5,KIF16B,C1orf122,TIMM44,YTHDF2,GEMIN5,DYRK1B,GLS,PAF1,UBTF,EPN2,GATA6,TP53BP1,PER1,EEFSEC,ARL4A,MKL2,PQBP1,ABCC3,COPS6,MAGI1,DMTF1,USP15,RELL2,AK2,CHST11,ZCCHC8,TAF1,PAX2,DPF2,UBXN1,ZFP36L1,EVPL,ETFB,DOPEY1,RNF40,MLX,VPS72,TIMELESS,CTR9,VAPB,LRSAM1,ZCCHC7,MSI2,WARS2,ELOVL6,TRA2A,XPO5,ELP3,BCS1L,PSMA1,OBSCN,WWC1,AGAP1,VAC14,TCF7L2,MGAT2,ATAD5,ITPRIPL1,SPAG9,SYNCRIP,SDCCAG8,TBPL1,SLC16A1,PTRH2,ARHGAP12,HMBS,DDX10,BRSK2,TCF12,SNX27,SART1,NDUFA5,DLL4,FEZ2,CYLD,PCNT,CELSR3,SLC2A1,LAGE3,PPP2R2A,RNF24,LPCAT3,TNKS1BP1,SEMA6A,GBF1,FDX1,DENR,CAD,VPS18,NRF1,JAG1,BRE,SOCS1,ARMC5,RNF2,CORO1A,FHIT,ADCK4,VCL,AUP1,HTRA2,TMLHE,MOSPD1,HN1,NARS2,TUBA1A,GLTSCR2,TFCP2,R3HDM1,POU2F1,MRRF,ATXN1,VIM,ATP8B2,RAB10,BATF3,TJAP1,SMAD3,EXO1,RBBP8,SLC30A3,HYAL3,IKZF4,LMBR1L,ALAD,KPNA3,SIX5,HNRNPR,KLF4,COPS5,ARNTL,TSSC1,ZNF436,PRRT3,FKBP5,MUTYH,PPIL3,SMG1,ATXN7L2,DMGDH,KLHL24,MINK1,DNAJA4,SUPT6H,FAM46B,RFX1,KLC4,CLSTN2,PPHLN1,ARFIP2,ATF7IP,APRT,POGZ,PIP4K2A,BZW2,C15orf57,ANKRD54,SLC25A20,PTPN2,SEC24C,DSG2,STC2,CLDND1,TTC17,PCK2,FBL,LDLRAD3,AMOT,SLC25A1,TOP1,AP4S1,GPHN,ADAMTSL3,IL11RA,MON1A,ANKMY2,PPP1R21,RAP1GDS1,SYMPK,POLR3G,CDH24,TPD52L2,GPC2,DSC2,ZBTB8OS,ZNF330,SET,TBX3,MSH3,MBD6,NFKBIB,NR2F2,KIF1B,ARHGAP27 |
| 1.720e-10 | -22.48 | brain | COSMIC cancer mutations | brain | 17017 | 2233 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RASSF3,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 2.140e-10 | -22.26 | SCGGAAGY_V$ELK1_02 | MSigDB lists | SCGGAAGY_V$ELK1_02 | 1135 | 218 | 17758 | 2279 |
CUL7,NF1,WDR74,FANCD2,PPIL1,SIRT2,SYNJ1,CUTC,GIT2,PABPC4,SLC30A7,PHF5A,ATG3,SLC39A7,AP1M1,VPS52,PRADC1,SLC35C2,YARS,OGG1,PRKACB,CSGALNACT2,SF3A1,CDC37,ZNF646,VPS13B,TNK2,NRAS,RBCK1,HARS,SIRT6,ITPA,RNMT,SEMA3F,MCL1,KRTCAP2,FOXRED1,SON,DLST,STOML2,YTHDF2,C1orf122,TMCO1,SSU72,DNAJC1,CCNT1,PER1,EEFSEC,E2F4,GALNT10,EME1,TNRC6A,CARS,EGR1,ANKRD17,LRRC28,ITFG1,UBXN1,MAPK8IP3,CLINT1,TIMM10,CEP164,RSPRY1,FAM192A,CNST,DHX37,COPS3,BANF1,PPIL2,TNPO3,CTR9,AGL,ZCCHC7,PABPC1,USE1,STAG1,TSTA3,RB1CC1,POLA1,XPO5,SUPT5H,VAC14,ZNF655,DAGLA,MGAT2,SEC31A,PALB2,GTF2A1,PDLIM1,NME7,ZZEF1,CCDC85B,PTRH2,PURB,GGT7,PDLIM5,SRP14,SART1,CHMP2A,SPRED2,PAPD4,KLHL18,NECAP1,AP1B1,UBL5,RING1,PAIP2,VPS18,SPG21,JAG1,SHC1,UBR1,ERI1,HIRIP3,RNF2,SSBP1,ADCK4,CPSF3,C6orf89,PRPF19,KDM3B,RFC4,GON4L,TFCP2,NARS,GLTSCR2,SFSWAP,MTIF2,RAB7A,R3HDM1,CCNDBP1,ARL5B,UBR4,DHX57,TMEM186,VPS53,EIF3H,WARS,ZFAND3,DNTTIP1,IQCH,ELP2,ALAD,ADNP,METTL6,WDR73,ALKBH1,PUS1,TMEM101,BRCC3,XRCC4,ZBTB11,AP2S1,PPIL3,YEATS2,ANKS1A,TMEM33,UNC13D,ESCO1,SHQ1,INSIG2,C17orf80,SUPT6H,C10orf2,PPHLN1,ARFIP2,SF3A3,AKT1S1,RBM19,BZW2,POGZ,PIP4K2A,SLC25A20,PTPN2,TADA3,POLR3D,NPRL2,GART,CTNNBL1,SEC24C,LTN1,COPS7B,HARS2,ARHGAP1,CELF1,LYPLA2,SLC25A1,NUDC,TTPAL,DDHD1,SMARCAD1,KDM5A,PPP1R21,ANKMY2,SCFD2,MRPS10,MARS,APTX,DDX49,C20orf196,DDX50,SRBD1,ZBTB8OS,WDR35,EIF2S1,ATM,ZRANB2,PGAM5,POLR1C,NFKBIB,BRWD3,RPS6KC1,NUDT22,ANAPC4,IPO4,DDIT3,LRRC41,STK4 |
| 2.334e-10 | -22.18 | nucleobase-containing compound biosynthetic process | biological process | GO:0034654 | 2957 | 491 | 16441 | 2138 |
ZNF292,MYCBP2,POLB,ASCC1,CUL4A,PRKAB2,HLTF,CCNL2,ZNF44,NUP160,GABPB2,LPIN1,MGA,SKI,ZNF37A,RPS16,SREBF2,ZFHX3,IKZF5,ATP5G2,RNF111,ME1,ZNF148,CHD2,KDM5C,MEIS3,ZNRD1,SEH1L,ZNF646,DPF3,HMBOX1,SETD1B,RNMT,NR6A1,UPP1,EYA3,NFIA,TCEB3,CUX1,RFX2,C5AR1,DENND4A,SAP30BP,ZNF197,STOML2,GZF1,DDX3X,SKIL,ZNF266,TRRAP,SUPT4H1,RAD18,CCNT1,ZNF81,HIC2,RUNX1,BMI1,ZNF532,PTPN14,MEF2C,BANP,IFT57,EGR1,TRIP6,ZHX3,KHDRBS1,SIRT7,GTF2IRD1,RSF1,CDC73,CHD5,HR,ZNF586,SCAF1,MYC,ATIC,ZNF326,MED24,GTF3C3,PRMT5,ZNF518B,PRPS1,MYB,GATAD2B,ZNF675,GTF2H3,WDR61,STAG1,PRIM2,RREB1,ZNF587,RB1CC1,PRDM16,POLA1,ARID5B,ZNF512B,USP10,SMARCD3,IMPDH2,ARID1A,NELFA,TRIM37,ONECUT2,SRA1,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,ASCC3,GTF2A1,NME7,RPL28,HIF1A,CDK9,SPEN,MED15,ZBTB12,SURF1,CCDC85B,ZNF160,PURB,UMPS,CNOT6,NCOR1,ZFHX2,ZNF254,ZNF516,TRERF1,GTF2H2C,NPAS2,ZBTB37,NUP43,FOSL2,SAFB2,RING1,TERF2IP,CHD7,FLAD1,ZNF827,KDM2A,ZKSCAN1,UCHL5,WAC,LPIN2,CMPK1,KMT2A,MTHFD2L,LSM10,CASP8AP2,SAP30,RFC4,RFC3,BRD4,KMT2D,GARS,ZNF480,NPM3,ATF7IP2,ATP6V0A1,SATB2,MED16,MEF2D,PNN,SETD7,SLC35D1,POLG2,MAT2A,FGFR1,ZBTB25,VDR,TAF2,BAZ1A,MSX2,DNTTIP1,SMARCC1,KDM4B,ELP2,HIPK2,G6PD,ZNF236,MBTD1,POLR3E,HOXA3,ZBTB11,TROVE2,COMMD10,HMGA2,NCOR2,ZNF786,C10orf2,TCF3,ZNF280C,NFX1,ID2,JMJD6,MYNN,TRIM22,BHLHE40,IKBKAP,FOXO3,MAD2L2,POM121,SFR1,ZNF483,TADA3,ZNF239,SNW1,POLR3D,COMMD9,PTRF,SUV39H2,ELP5,TAF3,YBX3,ZNF710,SOX6,FAM120B,TSHZ1,TTLL5,APEX1,POLK,ADSL,ZNF467,KLF6,FOXC1,UBC,POLR2A,RPA1,ZFP62,TRIB3,NSD1,SRCAP,BAZ2B,ZNF155,POLE2,ARID3B,ADK,DDIT3,KDM4C,KAT6A,ZNF76,PHF3,GPBP1L1,ATRX,KMT2E,PPARGC1B,POLR1A,RCHY1,CSNK2A1,ZNF107,BCOR,SIRT2,SNAPC4,BIRC2,SMARCB1,AMPD3,SRSF2,PHF5A,YLPM1,JAZF1,HKR1,PPCDC,RELB,ZEB1,POLR3B,ZNF85,POLE3,ZNF3,ETV1,ZMYM2,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,SESN2,ZNF124,TXLNG,ZNF195,PPARG,ZNF414,BAZ2A,ZNF680,MED27,MINA,HDAC8,BRCA1,KMT2C,SOX4,ZSCAN2,ZNF91,MLLT10,TAF9B,PAF1,GLS,UBTF,HPRT1,TCF7L1,GATA6,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,PQBP1,CRCP,DLX2,ZC3H8,ZNF397,BEND6,NOCT,DMTF1,EMSY,SARS,AK2,FOXO1,TAF1,PAX2,DPF2,LAMTOR3,SMAD7,HES6,MED13L,BARX2,ZIC2,RLF,ARID1B,NAMPT,DDIT4,ELL,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,GMDS,NRIP1,POLR1E,NT5E,MTHFD1,ZNF629,VOPP1,ZNF234,PAXBP1,TSTA3,PPAT,TLE3,ELP3,JMJD1C,SETD2,WBSCR22,ZFP14,LIG4,WWC1,PRDM1,SUPT5H,ISG15,TCF7L2,NR2F1,PWP1,ATXN7,MYBBP1A,RRAGA,TBPL1,ZNF430,ZFP90,TBL1X,ZBTB24,NR2C2AP,TCF12,MPI,ID1,ASH1L,SUCLG1,ARID2,RPS29,SMARCA4,PBX1,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,ZSCAN5A,CAD,RRN3,NRF1,ZBTB21,CAMTA2,NUP133,ZNF142,ZFP37,RNF2,FHIT,CPSF3,ZNF460,UTP4,MAML3,KAT8,KDM3B,PCGF3,PRAME,TFCP2,SFSWAP,GRHL3,ATXN1,POU2F1,NUP214,ZNF251,ATP5D,BATF3,SMAD3,RANBP2,IKZF4,ADNP,SIX5,COPS5,ZNF557,KLF4,ZNF333,ARNTL,CEBPZ,ATG7,ZNF436,SRFBP1,NFRKB,MED20,ZNF18,BRD9,ZNF507,DNAJC2,NIFK,SUPT6H,RFX1,AGO2,PPHLN1,APRT,MED18,ATF7IP,CHCHD10,FOXP1,ZNF594,GART,ZNF561,POLR1B,DMRT1,PKNOX1,SNAPC5,ARNTL2,TRNP1,MSX1,KDM5B,ZNF821,TEAD1,ZNF654,PSPC1,FOXN3,KDM5A,ZMYM5,SCMH1,ZNF324B,MEN1,ZNF407,POLR3A,RERE,ZNF221,POLR3G,ZNF708,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,NCBP2,ZNF32,MYRF,RBPJ,TAF12,POLR1C,NFKBIB,NR2F2 |
| 2.419e-10 | -22.14 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6650 | 988 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,WDR74,CNTNAP3,DCP1B,AARS2,MRPL10,CACNA1H,SBF2,CSPP1,HMOX2,SLC6A8,NUP160,ABHD6,LPAR3,CIAPIN1,PABPC4,AMBRA1,ZNF37A,PDZD2,SREBF2,IKZF5,NEK6,ZFHX3,NSRP1,SYN2,AP1M1,MAD1L1,FNIP2,KDM5C,HRG,SRRM2,CDK6,CNTNAP3B,CCDC57,NRAS,LIMA1,PTPRM,EHMT1,NFIA,C11orf80,C5AR1,AKAP12,MCL1,SHISA5,PLEKHM3,ABCC2,C10orf76,STOML2,SLC7A1,DDX3X,AHNAK,BRCA2,ZNF266,SSU72,LRRC40,TMEM139,RIOK1,ZNF532,RBP1,HERC2,EP400,EPM2AIP1,TRIP6,KHDRBS1,SIRT7,TRIO,PIK3R4,PARN,CDC73,PITPNM1,SLC1A1,ABCA7,RSPRY1,SH2B3,RBM20,DDX56,UBE3A,MCM5,ZNF326,MED24,GEMIN4,NOC3L,PRMT5,COQ3,MAP3K12,AGL,FMNL2,ANGPT2,FADS1,GATAD2B,PEA15,COL17A1,STAG1,MYO10,RB1CC1,PRDM16,ARID5B,TYW1,EPS15L1,EIF4A2,ZNF512B,RYR2,TRIM37,EVI5,USP46,ABCF1,ZNF655,ZNF783,RDH11,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,TASP1,GTF2A1,NME7,PDLIM1,CLASRP,EHMT2,TRAP1,ZNF160,GPN1,KIAA0196,WDR33,PDLIM5,MB21D2,SRP14,SGSM3,GALE,ABCA3,DNM3,ZNF516,BTBD2,PDK4,DDR2,MYH9,GRINA,STAM,MCM9,RPGRIP1L,PRKD3,CD96,ESAM,ABCA12,ZKSCAN1,SETD5,MSH4,ZC3H3,LYST,MALL,KMT2D,SLCO6A1,ADAM32,PCNXL2,KCNH3,SLC35D1,TTC28,DSP,MAT2A,FGFR1,TAF2,FBXL5,ARHGAP21,CDC16,KDM4B,ASTN2,HIPK2,PAM,HOXA3,RPS6KB1,BRCC3,ZBTB11,ANKS1A,LAMA5,METTL2B,YEATS2,CATSPERG,MAPT,TRIM36,LRCH1,MORC2,ZNF786,XPC,SESTD1,TRAK1,ATG2B,TRIM22,IP6K2,BHLHE40,ZNF691,MBNL1,POM121,NPRL2,SUV39H2,GATC,TAF3,UNC13A,ARHGAP1,C15orf41,SAMD4A,HNRNPM,SPTAN1,NUDC,DIS3L2,ULBP1,C21orf58,TTPAL,FAM98A,POLK,LSM12,ARHGAP39,ZC3H18,MRPS10,RSBN1,CCDC113,R3HDM2,PPIP5K2,UBE2K,PDE3B,CASC1,OXSR1,TRIB3,TOE1,NSD1,SRCAP,RARS,BAZ2B,HERC1,ACOX1,SLC25A19,GPAM,DOCK6,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,FAM227A,RBM33,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,FAM13A,TTI1,TMEM132A,SEC16A,COX10,NLE1,SCAF8,FRRS1,MAP2K3,ABL2,DHX33,PHKA1,XRCC2,ANKRD11,METTL8,ZNF85,RAN,ETV1,TMPO,VPS13B,SF3A1,CDC37,METTL1,FLNC,DBN1,CHD9,FMNL3,ABCC4,BAZ2A,SKIV2L2,PPARG,CDK4,ANK2,MED27,LAMA2,BRCA1,CRYBG3,LSG1,CCDC28B,KIF16B,PEX1,BSN,DYRK1B,GLS,TCF7L1,ZNF622,LSS,MSRA,TP53BP1,CHD3,EEFSEC,PER1,TECPR2,AHNAK2,C3orf35,MAGI1,USP15,SEPHS2,XYLB,AOC3,MCM6,CLK1,PRSS3,NKD2,SMAD7,MAPK8IP3,FAN1,BARX2,ZIC2,C1orf52,RLF,ARID1B,DNAH1,RNF40,DOPEY1,MLX,ZNF358,ABCA5,CEP290,NDRG4,TIMELESS,SYNJ2,GMDS,PNPLA3,SNX29,TRAPPC9,CAMKK2,TLE3,SETD2,UTP15,OBSCN,METTL22,SUPT5H,NR2F1,TCF7L2,GRIK4,ATXN7,FAM135A,SPAG9,PALB2,TTC38,DNAH17,CASS4,ZNF430,NAPA,PRKAR2A,ID1,PAPD4,SUCLG1,ARID2,RBFOX2,NTSR1,RIPK1,LPCAT3,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PELP1,DDX60L,URB1,PLXNB1,KDM1A,CAD,ZNF608,ANKRD13A,JAG1,DUS4L,NUP133,UBR1,ARMC5,DNAJB6,FGGY,FSIP2,IKBKB,CYB5D1,CCDC40,MYH15,RNF2,HIBCH,AHCYL1,KDM3B,SKIV2L,SOBP,SEC24A,TLCD1,WDR36,SSFA2,TEX19,THSD4,VIM,SLC35F2,AKAP13,NUP214,EIF3H,ZNF251,TMEM186,TJAP1,BTBD11,SMAD3,IFT81,RANBP2,RBBP8,SLC30A3,CLEC16A,ITGA2,ATG7,ZNF436,NFASC,FAHD1,PARD3,ATXN7L2,ZNF507,UNC13D,HM13,MAP3K13,RFX1,FAM46B,C14orf159,VARS,RBM19,ZNF346,CSNK1A1,RMI1,POGZ,BZW2,ZNF594,IQGAP2,NDUFV1,SACS,ZNF561,SURF2,IFIT5,PRICKLE2,GREB1,DDX31,CPNE7,PCK2,FAM71E1,ADAMTSL3,LRRIQ1,SMARCAD1,TEX14,TOP3A,DHX34,PEAR1,FERMT2,ARHGEF12,C11orf49,YIPF3,PALLD,GPNMB,PIK3CB,TMEM175,POLR3A,ZRANB3,CDH24,CACNB1,SAMD5,SRBD1,DSC2,ZBTB8OS,TBX3,GLG1,MSH3,EIF2S1,FNTB,USP20,TMEM219,RBM26,ITGB4,NR2F2,RPS6KC1,XPO6,KIF1B,C6orf223,ZNF292,MYCBP2,CGN,CUL4A,PRDX6,TNFRSF21,PLRG1,PRKCA,NBEAL1,AARS,UBR5,LPIN1,MGA,GIPR,EXOC1,RNF111,CHD2,CEP135,FUT11,CSGALNACT2,SPAG6,ZNF646,TBC1D8,DDN,SLC38A6,GDAP1,DPF3,ATG9A,ALDH1L2,CUX1,TCEB3,SEMA3F,SON,DENND4A,FOXRED1,DDX60,SAP30BP,TMEM206,PLCXD2,GNAI1,DOT1L,OSBPL1A,SKIL,DDAH2,TRRAP,HSDL2,FAM122C,SH3RF1,LSM14A,CCNT1,LUC7L3,HSPBAP1,CFD,VPS13D,XPNPEP1,GREB1L,DNAH2,WDR66,TXN2,BLMH,BMI1,ZNF598,SPOCK3,ZMAT3,NMD3,PTPN14,EFNB2,C9orf78,WDR75,IFT57,DROSHA,JUP,CELSR1,ANKRD17,GTF2IRD1,TGFBR2,NDUFS7,MTUS1,PRKCE,NAV1,HR,TSPAN2,NOVA2,SCAF1,USPL1,VWDE,SLC16A9,SAMD13,GTF3C3,LPCAT1,TERF2,ADARB1,SCAF11,SIK3,PRIM2,IFNGR2,SYNGAP1,SIGMAR1,AOC2,RAPGEF4,RABAC1,ARID1A,TPRA1,PLCB1,ZNF425,EPRS,ASCC3,MTHFD2,KIDINS220,ALKBH3,PMEPA1,NSF,VCAN,SPEN,ZZEF1,BIVM,ZCCHC6,RIOK3,NCOR1,IQSEC2,CNDP2,MAP2K4,HS2ST1,CPT1C,AMOTL1,TRPM2,CCDC58,LIN28B,BIRC6,ZBTB37,URB2,HFM1,UROD,KIAA0232,NDUFB5,KLHL18,TMEM104,PTPRG,CORO6,SLC25A44,FLNB,TRIM66,CHD7,FLAD1,TMEM184A,SHC1,GLYR1,VGF,LPIN2,DTNBP1,SHF,NBEA,TTC3,PNPLA4,KMT2A,CDK12,CASP8AP2,C18orf21,ZCCHC14,RFC4,BRD4,C1orf228,PDK1,MTIF2,PREX1,SATB2,MARCH6,MEGF11,POLG2,STK10,ERC1,DHX57,CPED1,DCBLD2,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,ZNF236,LARGE,IFT140,MDN1,KLHDC4,SETD6,XRCC4,NOLC1,NCOR2,SSH2,BRAF,UTP14A,TTC27,C10orf2,MRI1,KIF5C,SLC25A12,RTN4,MYNN,MLH1,MON2,DNAJC22,GIGYF2,FOXO3,REEP5,TMCO6,ABL1,DCTPP1,RGS17,PTRF,ELP5,NISCH,RDX,COPS7B,DYNC2H1,EXOSC4,LARP4B,PLEKHG4,NAV3,CLK2,TMC7,PFKFB4,FER1L5,SLC40A1,WDFY3,KCNMA1,WDR18,ADSL,PACS1,BMS1,APTX,OASL,C9orf153,KLF6,GUF1,NOP58,SLC23A2,KLHL22,RETSAT,ZDHHC11,ZNF155,IREB2,DDX50,HELZ,STX18,RNF138,ATM,SVIL,MYOM2,APAF1,BRWD3,ADK,IPO4,SLC43A1,LRRC41,STK4,IMMP2L,ZNF76,PHF3,UBN1,NF1,RARS2,KIF5A,PTPRA,FANCD2,TRPM6,RCHY1,PLOD1,PPIL1,ANKRD18A,SLC29A1,BCOR,STK33,CUTC,SNAPC4,SLC30A7,SMARCB1,PCYOX1L,ZNF804A,DST,ANAPC1,THADA,LONRF2,ZNHIT6,SLC39A7,GPR87,MYH3,ANAPC10,HYAL1,IPP,ZEB1,GPATCH1,KIAA0922,POLR3B,CCDC121,CARM1,PRKACB,TRIP13,SRPK2,TIMM50,LAMA4,TNK2,SKAP2,ZNF680,SLC38A1,ARRDC3,KSR2,CAV1,SGK2,KMT2C,TCTN1,CHAF1A,CCDC3,UBTF,GEMIN5,PAF1,SUFU,HLCS,CC2D1B,RLTPR,MKL2,CSMD3,ABCC3,GALNT10,EME1,CLU,DCAF5,MTCH1,TNRC6A,VIPR1,SLC12A7,FBXO45,FN1,RHOBTB1,TAF1,DPF2,PCSK7,MED13L,QSER1,EVPL,NAMPT,ELL,SIPA1L3,MCAM,ATXN2,ISPD,SEMA3D,NRIP1,ATP6V0D1,N4BP2,CPSF3L,ZNF629,MTHFD1,PPAT,TRA2A,ELOVL6,XPO5,ELP3,ZBED4,JMJD1C,ZFP14,WWC1,C11orf65,HERPUD1,DNAH14,POP1,SYCP2L,ATAD5,MYBBP1A,EP400NL,KIAA0355,FSCN1,INTS5,FAT1,KIAA0754,SDCCAG8,EXOC4,CDKAL1,SLC16A1,KIAA1328,TBL1X,TBCK,FNBP1L,PDE9A,C7orf26,N4BP2L2,DMXL2,ZNF706,ASH1L,PCNT,MMRN2,CELSR3,MYO7A,SMARCA4,TMEM177,SPATS2,ST7L,ARSJ,UBTD2,GBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,FARSA,KCTD11,MPHOSPH10,CAMTA2,PPFIBP1,RPS6KL1,CBR4,SNTG2,ZNF142,ADCK4,MET,ITGAX,TMEM120B,AUP1,MAML3,TFCP2,ATXN1,R3HDM1,TOR1AIP2,UBR4,TPK1,PLIN2,ZC3H12A,ARMC4,ALAD,ADNP,ZNF557,CEBPZ,TMEM101,NFRKB,HEATR1,SMG1,KLHL24,TNIK,BCKDK,SULT1C2,SH2D3A,C17orf80,SUPT6H,CAMK1,DYM,KLC4,H2AFJ,LETMD1,IGF2BP2,ATF7IP,CCDC7,SOGA1,FAM49A,MFHAS1,GFM2,BMP6,PIP4K2A,MFSD10,SFI1,HDDC2,PRKCH,GART,HAS3,DSG2,SHMT2,TTC17,FBL,ERI3,AMOT,MICAL3,SLC25A1,RPS6KB2,KDM6B,SLC6A16,DNMBP,PSPC1,KDM5A,ANKMY2,PSMC3IP,METTL23,ASAP3,SCMH1,ZNF324B,MARS,ARHGAP32,PDE2A,ZNF407,EIF5B,NAPEPLD,RERE,ZNF221,ZNF708,ALG5,SERINC1,WDR35,AGTPBP1,CUL2,ANKRD30BL,VPS37B,MBD6,PREPL,ZAK,SLC16A10,ZSWIM6,NIT1 |
| 2.419e-10 | -22.14 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6650 | 988 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,WDR74,CNTNAP3,DCP1B,AARS2,MRPL10,CACNA1H,SBF2,CSPP1,HMOX2,SLC6A8,NUP160,ABHD6,LPAR3,CIAPIN1,PABPC4,AMBRA1,ZNF37A,PDZD2,SREBF2,IKZF5,NEK6,ZFHX3,NSRP1,SYN2,AP1M1,MAD1L1,FNIP2,KDM5C,HRG,SRRM2,CDK6,CNTNAP3B,CCDC57,NRAS,LIMA1,PTPRM,EHMT1,NFIA,C11orf80,C5AR1,AKAP12,MCL1,SHISA5,PLEKHM3,ABCC2,C10orf76,STOML2,SLC7A1,DDX3X,AHNAK,BRCA2,ZNF266,SSU72,LRRC40,TMEM139,RIOK1,ZNF532,RBP1,HERC2,EP400,EPM2AIP1,TRIP6,KHDRBS1,SIRT7,TRIO,PIK3R4,PARN,CDC73,PITPNM1,SLC1A1,ABCA7,RSPRY1,SH2B3,RBM20,DDX56,UBE3A,MCM5,ZNF326,MED24,GEMIN4,NOC3L,PRMT5,COQ3,MAP3K12,AGL,FMNL2,ANGPT2,FADS1,GATAD2B,PEA15,COL17A1,STAG1,MYO10,RB1CC1,PRDM16,ARID5B,TYW1,EPS15L1,EIF4A2,ZNF512B,RYR2,TRIM37,EVI5,USP46,ABCF1,ZNF655,ZNF783,RDH11,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,TASP1,GTF2A1,NME7,PDLIM1,CLASRP,EHMT2,TRAP1,ZNF160,GPN1,KIAA0196,WDR33,PDLIM5,MB21D2,SRP14,SGSM3,GALE,ABCA3,DNM3,ZNF516,BTBD2,PDK4,DDR2,MYH9,GRINA,STAM,MCM9,RPGRIP1L,PRKD3,CD96,ESAM,ABCA12,ZKSCAN1,SETD5,MSH4,ZC3H3,LYST,MALL,KMT2D,SLCO6A1,ADAM32,PCNXL2,KCNH3,SLC35D1,TTC28,DSP,MAT2A,FGFR1,TAF2,FBXL5,ARHGAP21,CDC16,KDM4B,ASTN2,HIPK2,PAM,HOXA3,RPS6KB1,BRCC3,ZBTB11,ANKS1A,LAMA5,METTL2B,YEATS2,CATSPERG,MAPT,TRIM36,LRCH1,MORC2,ZNF786,XPC,SESTD1,TRAK1,ATG2B,TRIM22,IP6K2,BHLHE40,ZNF691,MBNL1,POM121,NPRL2,SUV39H2,GATC,TAF3,UNC13A,ARHGAP1,C15orf41,SAMD4A,HNRNPM,SPTAN1,NUDC,DIS3L2,ULBP1,C21orf58,TTPAL,FAM98A,POLK,LSM12,ARHGAP39,ZC3H18,MRPS10,RSBN1,CCDC113,R3HDM2,PPIP5K2,UBE2K,PDE3B,CASC1,OXSR1,TRIB3,TOE1,NSD1,SRCAP,RARS,BAZ2B,HERC1,ACOX1,SLC25A19,GPAM,DOCK6,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,FAM227A,RBM33,GPBP1L1,PPARGC1B,POLR1A,CSNK2A1,FAM13A,TTI1,TMEM132A,SEC16A,COX10,NLE1,SCAF8,FRRS1,MAP2K3,ABL2,DHX33,PHKA1,XRCC2,ANKRD11,METTL8,ZNF85,RAN,ETV1,TMPO,VPS13B,SF3A1,CDC37,METTL1,FLNC,DBN1,CHD9,FMNL3,ABCC4,BAZ2A,SKIV2L2,PPARG,CDK4,ANK2,MED27,LAMA2,BRCA1,CRYBG3,LSG1,CCDC28B,KIF16B,PEX1,BSN,DYRK1B,GLS,TCF7L1,ZNF622,LSS,MSRA,TP53BP1,CHD3,EEFSEC,PER1,TECPR2,AHNAK2,C3orf35,MAGI1,USP15,SEPHS2,XYLB,AOC3,MCM6,CLK1,PRSS3,NKD2,SMAD7,MAPK8IP3,FAN1,BARX2,ZIC2,C1orf52,RLF,ARID1B,DNAH1,RNF40,DOPEY1,MLX,ZNF358,ABCA5,CEP290,NDRG4,TIMELESS,SYNJ2,GMDS,PNPLA3,SNX29,TRAPPC9,CAMKK2,TLE3,SETD2,UTP15,OBSCN,METTL22,SUPT5H,NR2F1,TCF7L2,GRIK4,ATXN7,FAM135A,SPAG9,PALB2,TTC38,DNAH17,CASS4,ZNF430,NAPA,PRKAR2A,ID1,PAPD4,SUCLG1,ARID2,RBFOX2,NTSR1,RIPK1,LPCAT3,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PELP1,DDX60L,URB1,PLXNB1,KDM1A,CAD,ZNF608,ANKRD13A,JAG1,DUS4L,NUP133,UBR1,ARMC5,DNAJB6,FGGY,FSIP2,IKBKB,CYB5D1,CCDC40,MYH15,RNF2,HIBCH,AHCYL1,KDM3B,SKIV2L,SOBP,SEC24A,TLCD1,WDR36,SSFA2,TEX19,THSD4,VIM,SLC35F2,AKAP13,NUP214,EIF3H,ZNF251,TMEM186,TJAP1,BTBD11,SMAD3,IFT81,RANBP2,RBBP8,SLC30A3,CLEC16A,ITGA2,ATG7,ZNF436,NFASC,FAHD1,PARD3,ATXN7L2,ZNF507,UNC13D,HM13,MAP3K13,RFX1,FAM46B,C14orf159,VARS,RBM19,ZNF346,CSNK1A1,RMI1,POGZ,BZW2,ZNF594,IQGAP2,NDUFV1,SACS,ZNF561,SURF2,IFIT5,PRICKLE2,GREB1,DDX31,CPNE7,PCK2,FAM71E1,ADAMTSL3,LRRIQ1,SMARCAD1,TEX14,TOP3A,DHX34,PEAR1,FERMT2,ARHGEF12,C11orf49,YIPF3,PALLD,GPNMB,PIK3CB,TMEM175,POLR3A,ZRANB3,CDH24,CACNB1,SAMD5,SRBD1,DSC2,ZBTB8OS,TBX3,GLG1,MSH3,EIF2S1,FNTB,USP20,TMEM219,RBM26,ITGB4,NR2F2,RPS6KC1,XPO6,KIF1B,C6orf223,ZNF292,MYCBP2,CGN,CUL4A,PRDX6,TNFRSF21,PLRG1,PRKCA,NBEAL1,AARS,UBR5,LPIN1,MGA,GIPR,EXOC1,RNF111,CHD2,CEP135,FUT11,CSGALNACT2,SPAG6,ZNF646,TBC1D8,DDN,SLC38A6,GDAP1,DPF3,ATG9A,ALDH1L2,CUX1,TCEB3,SEMA3F,SON,DENND4A,FOXRED1,DDX60,SAP30BP,TMEM206,PLCXD2,GNAI1,DOT1L,OSBPL1A,SKIL,DDAH2,TRRAP,HSDL2,FAM122C,SH3RF1,LSM14A,CCNT1,LUC7L3,HSPBAP1,CFD,VPS13D,XPNPEP1,GREB1L,DNAH2,WDR66,TXN2,BLMH,BMI1,ZNF598,SPOCK3,ZMAT3,NMD3,PTPN14,EFNB2,C9orf78,WDR75,IFT57,DROSHA,JUP,CELSR1,ANKRD17,GTF2IRD1,TGFBR2,NDUFS7,MTUS1,PRKCE,NAV1,HR,TSPAN2,NOVA2,SCAF1,USPL1,VWDE,SLC16A9,SAMD13,GTF3C3,LPCAT1,TERF2,ADARB1,SCAF11,SIK3,PRIM2,IFNGR2,SYNGAP1,SIGMAR1,AOC2,RAPGEF4,RABAC1,ARID1A,TPRA1,PLCB1,ZNF425,EPRS,ASCC3,MTHFD2,KIDINS220,ALKBH3,PMEPA1,NSF,VCAN,SPEN,ZZEF1,BIVM,ZCCHC6,RIOK3,NCOR1,IQSEC2,CNDP2,MAP2K4,HS2ST1,CPT1C,AMOTL1,TRPM2,CCDC58,LIN28B,BIRC6,ZBTB37,URB2,HFM1,UROD,KIAA0232,NDUFB5,KLHL18,TMEM104,PTPRG,CORO6,SLC25A44,FLNB,TRIM66,CHD7,FLAD1,TMEM184A,SHC1,GLYR1,VGF,LPIN2,DTNBP1,SHF,NBEA,TTC3,PNPLA4,KMT2A,CDK12,CASP8AP2,C18orf21,ZCCHC14,RFC4,BRD4,C1orf228,PDK1,MTIF2,PREX1,SATB2,MARCH6,MEGF11,POLG2,STK10,ERC1,DHX57,CPED1,DCBLD2,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,ZNF236,LARGE,IFT140,MDN1,KLHDC4,SETD6,XRCC4,NOLC1,NCOR2,SSH2,BRAF,UTP14A,TTC27,C10orf2,MRI1,KIF5C,SLC25A12,RTN4,MYNN,MLH1,MON2,DNAJC22,GIGYF2,FOXO3,REEP5,TMCO6,ABL1,DCTPP1,RGS17,PTRF,ELP5,NISCH,RDX,COPS7B,DYNC2H1,EXOSC4,LARP4B,PLEKHG4,NAV3,CLK2,TMC7,PFKFB4,FER1L5,SLC40A1,WDFY3,KCNMA1,WDR18,ADSL,PACS1,BMS1,APTX,OASL,C9orf153,KLF6,GUF1,NOP58,SLC23A2,KLHL22,RETSAT,ZDHHC11,ZNF155,IREB2,DDX50,HELZ,STX18,RNF138,ATM,SVIL,MYOM2,APAF1,BRWD3,ADK,IPO4,SLC43A1,LRRC41,STK4,IMMP2L,ZNF76,PHF3,UBN1,NF1,RARS2,KIF5A,PTPRA,FANCD2,TRPM6,RCHY1,PLOD1,PPIL1,ANKRD18A,SLC29A1,BCOR,STK33,CUTC,SNAPC4,SLC30A7,SMARCB1,PCYOX1L,ZNF804A,DST,ANAPC1,THADA,LONRF2,ZNHIT6,SLC39A7,GPR87,MYH3,ANAPC10,HYAL1,IPP,ZEB1,GPATCH1,KIAA0922,POLR3B,CCDC121,CARM1,PRKACB,TRIP13,SRPK2,TIMM50,LAMA4,TNK2,SKAP2,ZNF680,SLC38A1,ARRDC3,KSR2,CAV1,SGK2,KMT2C,TCTN1,CHAF1A,CCDC3,UBTF,GEMIN5,PAF1,SUFU,HLCS,CC2D1B,RLTPR,MKL2,CSMD3,ABCC3,GALNT10,EME1,CLU,DCAF5,MTCH1,TNRC6A,VIPR1,SLC12A7,FBXO45,FN1,RHOBTB1,TAF1,DPF2,PCSK7,MED13L,QSER1,EVPL,NAMPT,ELL,SIPA1L3,MCAM,ATXN2,ISPD,SEMA3D,NRIP1,ATP6V0D1,N4BP2,CPSF3L,ZNF629,MTHFD1,PPAT,TRA2A,ELOVL6,XPO5,ELP3,ZBED4,JMJD1C,ZFP14,WWC1,C11orf65,HERPUD1,DNAH14,POP1,SYCP2L,ATAD5,MYBBP1A,EP400NL,KIAA0355,FSCN1,INTS5,FAT1,KIAA0754,SDCCAG8,EXOC4,CDKAL1,SLC16A1,KIAA1328,TBL1X,TBCK,FNBP1L,PDE9A,C7orf26,N4BP2L2,DMXL2,ZNF706,ASH1L,PCNT,MMRN2,CELSR3,MYO7A,SMARCA4,TMEM177,SPATS2,ST7L,ARSJ,UBTD2,GBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,FARSA,KCTD11,MPHOSPH10,CAMTA2,PPFIBP1,RPS6KL1,CBR4,SNTG2,ZNF142,ADCK4,MET,ITGAX,TMEM120B,AUP1,MAML3,TFCP2,ATXN1,R3HDM1,TOR1AIP2,UBR4,TPK1,PLIN2,ZC3H12A,ARMC4,ALAD,ADNP,ZNF557,CEBPZ,TMEM101,NFRKB,HEATR1,SMG1,KLHL24,TNIK,BCKDK,SULT1C2,SH2D3A,C17orf80,SUPT6H,CAMK1,DYM,KLC4,H2AFJ,LETMD1,IGF2BP2,ATF7IP,CCDC7,SOGA1,FAM49A,MFHAS1,GFM2,BMP6,PIP4K2A,MFSD10,SFI1,HDDC2,PRKCH,GART,HAS3,DSG2,SHMT2,TTC17,FBL,ERI3,AMOT,MICAL3,SLC25A1,RPS6KB2,KDM6B,SLC6A16,DNMBP,PSPC1,KDM5A,ANKMY2,PSMC3IP,METTL23,ASAP3,SCMH1,ZNF324B,MARS,ARHGAP32,PDE2A,ZNF407,EIF5B,NAPEPLD,RERE,ZNF221,ZNF708,ALG5,SERINC1,WDR35,AGTPBP1,CUL2,ANKRD30BL,VPS37B,MBD6,PREPL,ZAK,SLC16A10,ZSWIM6,NIT1 |
| 2.509e-10 | -22.11 | protein complex | cellular component | GO:0043234 | 4232 | 658 | 17570 | 2233 |
ASCC1,THOC5,ACTG1,MKS1,CACNA1H,TUBE1,CSPP1,CCNL2,NUP160,ABHD6,SYNJ1,NOS1AP,SKI,NEK6,SREBF2,ZFHX3,ATP5G2,RASSF3,AP1M1,EMC8,MAD1L1,ZNRD1,CDK6,EIF4E3,KLHL23,RNMT,EXOC6B,AP4B1,KIF15,MCL1,DCUN1D5,MCM2,STOML2,DDX3X,BRCA2,SUPT4H1,RAD18,FIS1,FIP1L1,MEF2C,TNNC1,EP400,TRIP6,KHDRBS1,SIRT7,PIK3R4,RSF1,KCNJ14,CDC73,ABCA7,CNST,UBE3A,EIF2S2,INTS7,MCM5,CACNB2,ZNF326,MED24,GEMIN4,PRMT5,AGL,EMC10,KLRD1,PEA15,GATAD2B,GTF2H3,TIMM8B,COL17A1,WDR61,KCNQ3,MYO10,RB1CC1,PRDM16,EPS15L1,EIF4A2,RYR2,ATAT1,SMARCD3,SNAP25,TRIM37,IRS1,DYNC1H1,LRP1B,GTF2A1,PDLIM1,CDK9,SENP3,CNOT6,KIAA0196,WDR33,COG5,DNM3,GTF2H2C,PAFAH1B1,NPAS2,ATP6V1A,ACTR3,VTI1A,MYH9,NECAP1,TUBB6,NUP43,EEA1,MCM9,HSPA1A,NDUFB3,RPP30,BCAS2,ZSWIM7,INTS12,MSH4,PXK,ZC3H3,PMS1,KMT2D,KRT7,EIF3J,ATP6V0A1,DSP,VPS53,MAT2A,FGFR1,PES1,GNG2,TAF2,FBXL5,HLA-DMA,CDC16,ELP2,NSMCE2,HIPK2,POLR3E,BRCC3,YEATS2,LAMA5,CATSPERG,CEP170,MAPT,HMGA2,INSIG2,XPC,SESTD1,ID2,AKT1S1,RNASEH2B,PSMF1,TTLL11,TADA3,SNW1,NPRL2,POLR3D,GATC,TAF3,CFDP1,FBXL19,ACTR3B,DIS3L2,NUDC,FAM98A,FBXO17,CEP83,VPS37A,CCDC113,IL6R,PDE3B,ANXA1,RPA1,SRCAP,RARS,POLE2,STX1A,IGBP1,ANAPC4,CUL7,BCAS4,PPARGC1B,POLR1A,CSNK2A1,TTI1,COX10,BIRC2,COPS4,PHKA1,NCKIPSD,XRCC2,UBAP2L,RAN,POLE3,CDC37,METTL1,RBCK1,ATF4,AEBP2,MIOS,SKIV2L2,PPARG,BAZ2A,CDK4,KATNAL1,HSPA5,MED27,NOL6,ATG12,SUMO3,BRCA1,KRTCAP2,KCNH2,DLST,CXADR,KIF16B,TCF7L1,INSIG1,TP53BP1,CHD3,E2F4,TNFRSF1A,RAD51B,TSEN2,CTU2,TTN,MCM6,STX8,LAMTOR3,SMAD7,HES6,BARX2,DNAH1,ARID1B,RNF40,SUB1,CEP290,MBD2,VPS72,GTF2H1,CTR9,ICE2,NAA38,LAMC1,IFT43,HAUS6,BCS1L,UTP15,RNH1,SUPT5H,VAC14,TCF7L2,ATXN7,GRIK4,SYNCRIP,SNAP23,DNAH17,TBPL1,NAPA,SH3PXD2A,PRKAR2A,BCCIP,NDUFA5,CYLD,OLFM2,PAPD4,SUCLG1,ARID2,PPP2R2A,RIPK1,RADIL,TNKS1BP1,PELP1,PLXNB1,KDM1A,CAD,NUP133,GRIN2C,UBR1,IKBKB,MYH15,ETF1,RNF2,CORO1A,CASP10,PRPF19,SKIV2L,SEC24A,KAT8,PCGF3,TUBA1A,RAB7A,C1QTNF1,VIM,ENC1,EIF3H,ATP5D,SMAD3,RANBP2,IFT81,RBBP8,TIMM17A,KLF4,ITGA2,INTS9,PUS1,MED20,EIF2B3,AP2S1,PARD3,MCM10,HM13,MAP3K13,AGO2,MAP1S,CSNK1A1,HIST2H2AB,IQGAP2,NDUFV1,HIST2H3D,POLR1B,FBXO31,CD44,ABCF2,TPM4,TEX14,FERMT2,RANGAP1,HIST1H4J,EXOG,PALLD,PIK3CB,CHCHD6,POLR3A,POLR3G,CACNB1,ZBTB8OS,ADAT2,TAF4,SET,MSH3,BCAS3,EIF2S1,FNTB,RBPJ,TAF12,ITGB4,KIF1B,GCSH,CGN,POLB,CUL4A,PRKAB2,PLRG1,RAC3,MGA,EXOC1,RNF111,VPS52,SEH1L,SPAG6,SNU13,DPF3,SETD1B,NR6A1,EYA3,GNG7,TCEB3,CAMSAP2,SUPT20H,HIST1H2BL,FOXRED1,CLNS1A,SH3GL1,SPOP,GNAI1,SKIL,TRRAP,CCNT1,NSMCE1,DNAH2,NRP1,BMI1,WDR75,IFT57,DROSHA,JUP,CCDC53,PRPF31,DPM3,SSR4,TGFBR2,CHD5,NDUFS7,MTUS1,NAV1,HR,COPS3,MYC,GTF3C3,IGF2BP1,PLEKHA2,CNOT4,PRPS1,CAV2,TERF2,EXOSC2,PRIM2,ANAPC13,POLA1,TTYH2,PTPN12,ARID1A,NELFA,ARIH2,PHF6,SEC31A,EPRS,KIDINS220,HIF1A,UBAP1,SPEN,MED15,PURB,NCOR1,CPT1C,VMA21,AMOTL1,NDUFB5,C1QTNF7,KLHL18,SPATS2L,POP5,AP1B1,RING1,BLOC1S2,TERF2IP,PHC2,SLX4,SHC1,UCHL5,DTNBP1,RMDN3,KMT2A,CDK12,ATP6AP1L,NAA35,SAP30,RFC4,BRD4,RFC3,PDK1,DLG4,LRRC8A,SATB2,MED16,PNN,MARCH6,SERP1,ERC1,SNCA,VDR,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,DCXR,DNAJA3,H2AFX,IFT140,TRAF3,ANXA2,XRCC4,MID1,NCOR2,TCF3,KIF5C,MLH1,IKBKAP,MAD2L2,NEDD4,SFR1,PTRF,ELP5,TRIAP1,COPS7B,UPF2,EXOSC4,DYNC2H1,PXN,TTLL5,WDFY3,KCNMA1,POLR2A,FBXO21,KLHL22,COL26A1,STX18,ORC5,ATM,SVIL,MYOM2,NDUFS5,APAF1,IPO4,DDIT3,STK4,KAT6A,IMMP2L,EIF3C,KMT2E,ATRX,PTPRA,KIF5A,RCHY1,BCOR,SIRT2,SNAPC4,SMARCB1,DST,SRPRB,ANAPC1,RAP1A,KANSL1,CNIH3,JAZF1,ATG3,ANAPC11,ANAPC10,MYH3,IPP,ZEB1,RELB,POLR3B,NDUFA6,SLC27A5,OGG1,CARM1,PRKACB,TIMM50,TNK2,DEAF1,FBXW4,MINA,TMEM216,HDAC8,CAV1,SOX4,KMT2C,TCTN1,ARPC3,TAF9B,CHAF1A,GEMIN5,RHOU,PAF1,EPN2,GATA6,RLTPR,CRCP,BBIP1,CLU,COPS6,ZC3H8,DCAF5,DCTN3,VIPR1,FN1,TAF1,SEC24D,STXBP6,PAX2,UBXN1,DPF2,MED13L,TIMM10,TOX4,CEP164,ELL,NRIP1,AKAP11,POLR1E,ATP6V0D1,CPSF3L,KRT20,HBG2,XPO5,ELP3,PSMA1,WWC1,LIG4,EIF2A,BLOC1S4,C19orf70,HERPUD1,UBE2E1,DNAH14,EXOC6,POP1,MYBBP1A,BICD1,FSCN1,INTS5,EXOC4,RRAGA,TBL1X,PFDN2,PDSS2,AGO3,N4BP2L2,TCF12,CHMP2A,SNX27,PCNT,MYO7A,PIGH,TNXB,SMARCA4,PBX1,VPS18,FARSA,BRE,MPHOSPH10,SNTG2,ITGAX,CPSF3,VCL,UTP4,GNG5,HTRA2,AUP1,COL5A2,ATXN1,RAB10,COPS5,ARNTL,HEATR1,NFRKB,KLHL24,BCKDK,KLC4,H2AFJ,PDE4B,ATF7IP,MED18,CTNNBL1,SCN1B,SEC24C,DCTN4,AMOT,PKNOX1,TOP1,ARNTL2,PPP1R9B,KDM5A,MEN1,HSPA1B,RERE,WDR35,MPP7,CUL2,VPS37B,NCBP2,POLR1C |
| 2.696e-10 | -22.03 | GARY_CD5_TARGETS_DN | MSigDB lists | GARY_CD5_TARGETS_DN | 418 | 100 | 17758 | 2279 |
BCCIP,CUL4A,DDX18,PAFAH1B1,PPIL1,IKBIP,TTI1,NUP160,SLC30A7,NOP56,FLAD1,FARSA,SRSF2,IKZF5,THADA,NUP133,UCHL5,DNAJB6,UBAP2L,PAK1IP1,ETF1,RAN,POLE3,MET,LSM10,CDK12,IPO11,WDR36,GDAP1,RFC3,EIF3J,AP4B1,TSN,HSPA5,TCEB3,GMFB,NLN,KIAA1586,PNN,ARL5B,TAF9B,HLA-DMA,SSU72,TRMT5,CEBPZ,PQBP1,SRFBP1,HEATR1,NOLC1,TMEM33,USP15,PRPF38B,CHST11,FOXO1,LARS2,C10orf2,IKBKAP,PDCD5,PSMF1,MRPS11,DCTPP1,TANK,PMPCA,GTF2H1,GEMIN4,CNOT4,SERBP1,HNRNPM,RABEPK,NUDC,FAM98A,RANBP6,AP4S1,STAG1,ABCF2,UTP15,ADSL,APTX,PALLD,ZNF407,CYB5B,UBE2K,NOP58,POLR3G,MRPL36,MGAT2,ASCC3,RARS,POLE2,SYNCRIP,INTS5,CUL2,RNF138,EIF2S1,SLC25A19,UMPS,CNDP2,POLR1C,GPATCH4,ZBTB24 |
| 2.805e-10 | -21.99 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 17034 | 2234 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,IGF2BP2,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,TMEM241,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 2.916e-10 | -21.96 | Aminoacyl-tRNA biosynthesis | KEGG pathways | hsa00970 | 44 | 23 | 6908 | 881 |
NARS2,CARS,SARS,WARS2,GARS,NARS,HARS,LARS2,RARS2,AARS2,FARS2,MARS,VARS,AARS,TARS,YARS2,WARS,FARSA,EPRS,RARS,GATC,HARS2,YARS |
| 2.916e-10 | -21.96 | Aminoacyl-tRNA biosynthesis | KEGG pathways | ko00970 | 44 | 23 | 6908 | 881 |
NARS2,CARS,SARS,GARS,WARS2,NARS,LARS2,HARS,RARS2,AARS2,FARS2,MARS,VARS,AARS,TARS,YARS2,WARS,RARS,EPRS,FARSA,GATC,HARS2,YARS |
| 3.205e-10 | -21.86 | CSNK2A1 (casein kinase 2, alpha 1 polypeptide) | protein interactions | 1457 | 466 | 116 | 16036 | 2270 |
THOC5,CUL7,EIF3C,RBM33,BIRC6,PAFAH1B1,MYH9,RSL1D1,CSNK2A1,SPATS2L,HMOX2,TNKS1BP1,KDM1A,RING1,ZC3H13,NOP56,RIOK2,NRF1,MPHOSPH10,SRSF2,COPS4,HIRIP3,RNF111,RNF2,SRRM2,FTSJ3,PRKACB,CDC37,TMPO,SF3A1,PCGF3,EIF3J,GMFB,CAV1,PNN,BRCA1,DKC1,MCM2,MAK16,SAP30BP,FKBP3,EIF3H,CLNS1A,SNCA,PAF1,UBTF,VDR,DDX3X,SUPT4H1,CHD3,LSM14A,COPS5,H2AFX,HSPB8,RPS6KB1,ZC3H8,FIP1L1,NOLC1,XRCC4,NMD3,MAPT,MEF2C,HMGA2,EGR1,FN1,UTP14A,SUPT6H,TAF1,SIRT7,HES6,KIF5C,RSF1,NOL3,PIP4K2A,RSRC1,SUB1,EIF2S2,CFDP1,MYC,COPS3,CTR9,ANP32B,CAV2,SERBP1,TOP1,MYB,IFRD1,APEX1,DDX24,FGF2,SMARCAD1,RANGAP1,BMS1,PACS1,SUPT5H,EIF5B,NOP58,UBC,TCF7L2,POLR2A,ISG15,POP1,IRS1,INF2,GTF2A1,STX1A,HIF1A,EIF2S1,GPN1,PURB,DTD1,ZRANB2,NCOR1,NFKBIB,BRWD3,DDIT3 |
| 3.306e-10 | -21.83 | tRNA Aminoacylation | REACTOME pathways | R-HSA-379724 | 42 | 23 | 8202 | 1117 |
CARS,NARS2,SARS,GARS,WARS2,NARS,LARS2,HARS,RARS2,AARS2,FARS2,VARS,MARS,AARS,TARS,YARS2,WARS,FARSA,RARS,EPRS,HARS2,YARS,PPA1 |
| 3.322e-10 | -21.83 | DNA metabolic process | biological process | GO:0006259 | 766 | 160 | 16441 | 2138 |
POLB,ASCC1,CUL4A,KMT2E,ATRX,FANCD2,RCHY1,HLTF,UBR5,SMARCB1,COPS4,XRCC2,RNF111,RAN,POLE3,OGG1,LONP1,TRIP13,SESN2,SIRT6,BAZ2A,NOL8,EHMT1,TSN,EYA3,NFIA,SUMO3,BRCA1,MCM2,CHAF1A,BRCA2,TRRAP,RAD18,TP53BP1,NSMCE1,RAD51B,EME1,CCNB1IP1,COPS6,EMSY,HERC2,MCM6,TATDN3,FAN1,RLF,CHD5,CEP164,APLF,MCM5,COPS3,BANF1,GTF2H1,TIMELESS,TERF2,NT5E,GATAD2B,GTF2H3,PRIM2,POLA1,SETD2,LIG4,USP10,SUPT5H,ISG15,TCF7L2,ASCC3,KPNA1,MYBBP1A,PALB2,EHMT2,ALKBH3,CDK9,DTD1,WDR33,BCCIP,USP7,GTF2H2C,HFM1,TNKS1BP1,RPAIN,MCM9,TERF2IP,BRE,SLX4,ACD,KDM2A,ZSWIM7,ERI1,UCHL5,ATRIP,SSBP1,FHIT,MSH4,KMT2A,SPIDR,CTC1,PRPF19,RFC4,PMS1,RFC3,PARP2,DKC1,POLG2,RAD54B,BAZ1A,EXO1,RBBP8,KDM4B,COPS5,DNAJA3,NSMCE2,H2AFX,ALKBH1,NFRKB,BRCC3,XRCC4,MUTYH,SMG1,HMGA2,DNAJC2,MCM10,XPC,C10orf2,TCF3,DBF4,ATF7IP,MLH1,RMI1,MAD2L2,SFR1,ABL1,HIST2H3D,COPS7B,EXOSC4,ERI3,NT5M,TOP1,APEX1,GINS3,POLK,SMARCAD1,PSMC3IP,TOP3A,APTX,HIST1H4J,MEN1,EXOG,POLR2A,UBC,ZRANB3,RPA1,ANXA1,POLE2,GADD45A,ORC5,SET,MSH3,ATM,RBPJ,TATDN1 |
| 3.761e-10 | -21.70 | CACGTG_V$MYC_Q2 | MSigDB lists | CACGTG_V$MYC_Q2 | 976 | 192 | 17758 | 2279 |
CGN,TNFRSF21,PPARGC1B,NAT10,RNF43,GYG1,BCOR,UBR5,PABPC4,NEK6,ATG3,ZNHIT6,SLC39A7,RELB,SUCLG2,JOSD1,ETV1,LONP1,TIMM50,NRAS,ATF4,ABCC4,TXLNG,NR6A1,NOL8,ARRDC3,NOL6,GMFB,AKAP12,SEMA3F,KRTCAP2,MCM2,ODC1,SLC9A5,DDX3X,DYRK1B,TOM1L2,PER1,HSPBAP1,CTAGE5,MPV17,DLX2,EME1,USP15,CHST11,AK2,ANKRD17,ST6GAL1,UBXN1,RLF,TIMM10,SLC39A11,MTUS1,IGF2BP3,DOPEY1,FAM192A,RSPRY1,PRKCE,CNST,SLC38A5,ATIC,GTF2H1,IGF2BP1,GEMIN4,ALDH18A1,CNOT4,ZCCHC7,PRPS1,PABPC1,ANGPT2,SERBP1,MYB,MTHFD1,BDNF,CAMKK2,ANAPC13,SIGMAR1,PPAT,POLA1,TLE3,XPO5,KIAA0586,ARRDC4,TRIM37,CPT1A,C19orf70,HERPUD1,POP1,SYNCRIP,GTF2A1,HIF1A,ARHGAP12,PFDN2,TBL1X,MACROD1,NAPA,OLFM2,CELSR3,DDX18,ATP6V1A,SPATA2L,TNXB,LCLAT1,DHX35,NOP56,CAD,SPG21,ARMC6,VGF,GLYR1,SLC38A2,CEP63,RTN4RL2,ARHGAP17,EIF3J,NLN,SATB2,GNL1,UBR4,MAT2A,USP36,BATF3,PES1,CAMK2D,ADNP,POLR3E,HOXA3,TRMT2A,FKBP5,SRFBP1,PUS1,MDN1,ZBTB11,YEATS2,SMG1,RAB30,ATXN7L2,MINK1,SCAMP3,UTP14A,DYM,CMTM8,NFX1,RTN4,ATF7IP,BHLHE40,TGFB2,RBM19,RPS6KA5,FOXO3,MBNL1,BMP6,MFHAS1,GIGYF2,IQGAP2,DCTPP1,PRKCH,POLR3D,ACAP3,DCTN4,STC2,SHMT2,CELF1,FBL,FBXL19,HNRNPM,NUDC,TOP1,PPP1R9B,APEX1,MON1A,SCFD2,LDHA,NOP58,POLR3A,RPA1,CTIF,ZBTB8OS,HNRNPH3,SET,VPS37B,BCAS3,SLCO5A1,AEN,BMP4,ADK,GCSH,KDM4C,IPO4,NIT1,SLC43A1,KAT6A |
| 3.906e-10 | -21.66 | transferase complex | cellular component | GO:1990234 | 710 | 148 | 17570 | 2233 |
CUL7,CUL4A,KMT2E,PRKAB2,POLR1A,PLRG1,RCHY1,CCNL2,MGA,ANAPC1,PHKA1,KANSL1,ATG3,ANAPC11,ANAPC10,UBAP2L,IPP,POLR3B,POLE3,ZNRD1,CDK6,PRKACB,METTL1,RBCK1,FBXW4,AEBP2,SETD1B,KLHL23,CDK4,MED27,SUPT20H,DCUN1D5,BRCA1,KRTCAP2,KMT2C,DLST,CLNS1A,SPOP,TAF9B,PAF1,TRRAP,RAD18,CCNT1,CRCP,BMI1,DCAF5,WDR75,EP400,PRPF31,TAF1,PIK3R4,DPM3,TGFBR2,CDC73,RNF40,INTS7,GTF2H1,MED24,CTR9,PRMT5,POLR1E,PRPS1,CPSF3L,NAA38,GTF2H3,ANAPC13,WDR61,RB1CC1,POLA1,ELP3,TRIM37,VAC14,ARIH2,UBE2E1,IRS1,ATXN7,GTF2A1,CDK9,INTS5,TBPL1,SENP3,PRKAR2A,PDSS2,BCCIP,PAPD4,KLHL18,HSPA1A,PELP1,EEA1,RING1,PHC2,BRE,UBR1,IKBKB,INTS12,RNF2,KMT2A,CDK12,NAA35,AUP1,KAT8,KMT2D,BRD4,MARCH6,ENC1,ERC1,MAT2A,FBXL5,TAF2,CDC16,ELP2,DNAJA3,POLR3E,INTS9,MED20,BRCC3,YEATS2,KLHL24,MAP3K13,MED18,IKBKAP,MAD2L2,NEDD4,TADA3,SNW1,POLR3D,TAF3,POLR1B,FBXO31,FBXL19,FBXO17,KDM5A,MEN1,PIK3CB,POLR2A,POLR3A,POLR3G,HSPA1B,KLHL22,FBXO21,POLE2,CUL2,TAF4,FNTB,TAF12,POLR1C,ANAPC4,KAT6A |
| 3.929e-10 | -21.66 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | 673 | 143 | 17758 | 2279 |
ATRX,RARS2,MRPS30,ANAPC1,S100A10,PMAIP1,YARS,CDK6,TMPO,SESN2,NRAS,MIOS,SLC38A1,NOL8,GMFB,ATG12,WDHD1,MTHFD1L,MCM2,DDX3X,SLC7A1,BRCA2,AHNAK,TRMT5,AHNAK2,SEMA3C,RUNX1,TMEM158,NMD3,LPP,USP15,CARS,FBXO45,WDR75,FN1,VTA1,TRIO,RSF1,QSER1,RLF,SPIRE1,IGF2BP3,NAMPT,EIF2S2,SLC7A11,ASAP1,ZCCHC7,ZNF675,IFRD1,PRIM2,STAG1,ELOVL6,EIF4A2,HAUS6,UTP15,PTPN12,USP10,LIG4,SNAP25,PLCB1,MBNL2,ONECUT2,ZNF655,EPRS,ASCC3,MTHFD2,NME7,VCAN,IRAK2,HK2,ZNF160,SLC16A1,GALE,VMA21,CELSR3,SLC2A1,NOP56,RIOK2,DENR,ASNS,MPHOSPH10,SLC38A2,TTC3,CEP63,CPSF3,PEG10,SERPINH1,MTHFD2L,HN1,MOSPD1,PMS1,WDR36,SSFA2,NLN,TOR1AIP2,PNN,ENC1,WARS,DCBLD2,DNTTIP1,RBBP8,CEBPZ,ACP1,RPS6KB1,ANXA2,BRCC3,XRCC4,ZBTB11,TRIM36,HMGA2,SUPT6H,B4GALT5,DBF4,IGF2BP2,CSNK1A1,GFM2,RSRC1,MBNL1,GART,DSG2,TANK,STC2,SHMT2,DYNC2H1,TOP1,TTPAL,ARNTL2,PSAT1,KCNMA1,TPM4,EIF5B,TARS,MKX,TRIB3,RARS,ORC5,EIF2S1,NCBP2,ADK,MTMR1,MIPOL1,HRH1,STK4 |
| 4.020e-10 | -21.63 | angiosarcoma | COSMIC cancer mutations | angiosarcoma | 2284 | 388 | 17775 | 2278 |
ARHGAP26,ADAM19,CNTNAP3,CACNA1H,SBF2,ENAH,CSPP1,LPIN1,SKI,TOM1L1,PCDH7,PDZD2,ZFHX3,ATP5G2,FAAH2,RABGAP1L,MAD1L1,ZNF148,ME1,AVEN,CNTNAP3B,SEH1L,NRAS,PTPRM,UPP1,KIF15,CUX1,RFX2,WDHD1,ABCC2,OSBPL1A,DOT1L,TRRAP,HSDL2,VPS13D,SEMA3C,GREB1L,RUNX1,NMD3,HERC2,IFT57,NHS,OPHN1,PIK3R4,PID1,CCDC47,PARN,ABCA7,SLC39A11,ANXA10,IGF2BP3,RBM20,PRKCE,UBE3A,DHX37,ASAP1,COPS3,VWDE,PIGG,MED24,IGF2BP1,MFAP2,FMNL2,SAMD3,SIK3,EXOSC2,STAG1,KCNQ3,PRIM2,PRDM16,RAPGEF4,RAP1GAP2,RYR2,ATAT1,PTPN12,USP10,PLCB1,ONECUT2,DYNC1H1,ZNF425,ASCC3,VPS13C,LRP1B,TASP1,KIDINS220,NME7,PDLIM1,TRAP1,PMEPA1,VCAN,ZZEF1,MED15,ZNF160,UMPS,NCOR1,MB21D2,ARHGAP10,COG5,RTTN,TBKBP1,ZNF516,LIN28B,PAFAH1B1,HFM1,VTI1A,MYH9,PTPRG,ST3GAL6,SLC25A44,RPGRIP1L,PAIP2,ZNF827,ABCA12,TBC1D22A,WAC,DTNBP1,SHF,NBEA,PNPLA4,DENND1A,ZCCHC14,MPP6,KMT2D,C1orf228,FAM111B,WDPCP,SLCO6A1,PCNXL2,SATB2,TTC28,TBC1D16,STK10,ERC1,FGFR1,PDE8B,HTR7,CAMK2D,CDC16,KDM4B,ASTN2,NSMCE2,ZNF236,WDR7,LARGE,ACP1,IFT140,CBWD1,MDN1,ANXA2,ANKS1A,MID1,COMMD10,BRAF,TTC27,TCF3,FARS2,RCAN1,RTN4,ATG2B,OPA1,RSRC1,REEP5,MBNL1,FAM8A1,NPRL2,NEBL,CFDP1,RDX,ACTR3B,SOX6,PFKFB4,VPS37A,TTLL5,CLYBL,LDHA,PACS1,OASL,UBE2K,PDE3B,CASC1,RPA1,KLHL22,SRCAP,PXDN,ACOX1,SLCO5A1,PTPN4,MYOM2,NDUFS5,SORCS2,BRWD3,CORO2B,IMMP2L,NF1,RARS2,KIF5A,TFIP11,SLC25A21,ZNF107,SIRT2,FAM13A,COX10,EDC3,RTN1,ZNF804A,ANAPC1,THADA,JAZF1,MYH3,GPATCH1,POLR3B,PCOLCE2,CCDC121,CARM1,CEP128,VPS13B,DSC3,FLNC,DTNB,DEAF1,GPM6A,SKAP2,ITPA,CMIP,ANK2,COL4A3BP,KSR2,HDAC8,LAMA2,MTHFD1L,SERGEF,CHAF1A,TMEM132B,EPN2,HLCS,TP53BP1,DNAJC1,FAM114A2,CCDC146,CSMD3,ADAM9,ASB3,VIPR1,XYLB,CHST11,ITFG1,MED13L,EVPL,ARID1B,RHBDD1,KIAA1958,ISPD,VAPB,CCDC124,ZCCHC7,SNX29,TRAPPC9,CRADD,SETD2,HAUS6,C11orf65,CORIN,AGAP1,CYB5B,DNAH14,VAC14,TBC1D2,GRIK4,ATXN7,BICD1,FAT1,SDCCAG8,EXOC4,SNX24,TMEM117,SIL1,CASS4,CDKAL1,PPP1R12B,KIAA1328,ARHGAP12,ZFP90,DDX10,TBCK,PDSS2,PRKAR2A,DMXL2,TCF12,USP7,CHMP2A,ASH1L,PCNT,SUCLG1,PAPD4,NTSR1,SSBP2,RADIL,URB1,GBF1,FDX1,ANKRD13A,JAG1,MPHOSPH10,NUP133,UBR1,SNTG2,MYH15,ZFP37,FHIT,ADCK4,MET,VCL,AUP1,SOBP,NARS2,RTN4RL2,PCGF3,AKAP8L,FAM172A,THSD4,MANBAL,MRRF,AKAP13,TPK1,BTBD11,SMAD3,ARMC4,RANBP2,CLEC16A,ITGA2,ATG7,SRFBP1,PUS1,SMG1,PARD3,TMCC1,DMGDH,SH2D3A,DYM,CMTM8,DBF4,CLSTN2,C14orf159,SEMA3E,CCDC7,PPP1R1C,RBM19,GFM2,ZNF594,PTPN2,SACS,CWC27,TMEM161A,SEC24C,DSG2,CD44,TTC17,LDLRAD3,DMRT1,HSD17B12,KDM6B,SLC6A16,ARNTL2,CRIM1,SCFD2,RAP1GDS1,FERMT2,C11orf49,PALLD,ZNF407,EIF5B,NAALADL2,PIK3CB,ARMC3,RERE,POLR3G,NOL10,SRBD1,SET,BCAS3,GLG1,PREPL,RPS6KC1,MMP16,MIPOL1,ZAK,SLC16A10,ZSWIM6 |
| 4.020e-10 | -21.63 | soft_tissue-blood_vessel-angiosarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-angiosarcoma | 2284 | 388 | 17775 | 2278 |
ARHGAP26,ADAM19,CNTNAP3,CACNA1H,SBF2,ENAH,CSPP1,LPIN1,SKI,TOM1L1,PCDH7,PDZD2,ZFHX3,ATP5G2,FAAH2,RABGAP1L,MAD1L1,ZNF148,ME1,AVEN,CNTNAP3B,SEH1L,NRAS,PTPRM,UPP1,KIF15,CUX1,RFX2,WDHD1,ABCC2,OSBPL1A,DOT1L,TRRAP,HSDL2,VPS13D,SEMA3C,GREB1L,RUNX1,NMD3,HERC2,IFT57,NHS,OPHN1,PIK3R4,PID1,CCDC47,PARN,ABCA7,SLC39A11,ANXA10,IGF2BP3,RBM20,PRKCE,UBE3A,DHX37,ASAP1,COPS3,VWDE,PIGG,MED24,IGF2BP1,MFAP2,FMNL2,SAMD3,SIK3,EXOSC2,STAG1,KCNQ3,PRIM2,PRDM16,RAPGEF4,RAP1GAP2,RYR2,ATAT1,PTPN12,USP10,PLCB1,ONECUT2,DYNC1H1,ZNF425,ASCC3,VPS13C,LRP1B,TASP1,KIDINS220,NME7,PDLIM1,TRAP1,PMEPA1,VCAN,ZZEF1,MED15,ZNF160,UMPS,NCOR1,MB21D2,ARHGAP10,COG5,RTTN,TBKBP1,ZNF516,LIN28B,PAFAH1B1,HFM1,VTI1A,MYH9,PTPRG,ST3GAL6,SLC25A44,RPGRIP1L,PAIP2,ZNF827,ABCA12,TBC1D22A,WAC,DTNBP1,SHF,NBEA,PNPLA4,DENND1A,ZCCHC14,MPP6,KMT2D,C1orf228,FAM111B,WDPCP,SLCO6A1,PCNXL2,SATB2,TTC28,TBC1D16,STK10,ERC1,FGFR1,PDE8B,HTR7,CAMK2D,CDC16,KDM4B,ASTN2,NSMCE2,ZNF236,WDR7,LARGE,ACP1,IFT140,CBWD1,MDN1,ANXA2,ANKS1A,MID1,COMMD10,BRAF,TTC27,TCF3,FARS2,RCAN1,RTN4,ATG2B,OPA1,RSRC1,REEP5,MBNL1,FAM8A1,NPRL2,NEBL,CFDP1,RDX,ACTR3B,SOX6,PFKFB4,VPS37A,TTLL5,CLYBL,LDHA,PACS1,OASL,UBE2K,PDE3B,CASC1,RPA1,KLHL22,SRCAP,PXDN,ACOX1,SLCO5A1,PTPN4,MYOM2,NDUFS5,SORCS2,BRWD3,CORO2B,IMMP2L,NF1,RARS2,KIF5A,TFIP11,SLC25A21,ZNF107,SIRT2,FAM13A,COX10,EDC3,RTN1,ZNF804A,ANAPC1,THADA,JAZF1,MYH3,GPATCH1,POLR3B,PCOLCE2,CCDC121,CARM1,CEP128,VPS13B,DSC3,FLNC,DTNB,DEAF1,GPM6A,SKAP2,ITPA,CMIP,ANK2,COL4A3BP,KSR2,HDAC8,LAMA2,MTHFD1L,SERGEF,CHAF1A,TMEM132B,EPN2,HLCS,TP53BP1,DNAJC1,FAM114A2,CCDC146,CSMD3,ADAM9,ASB3,VIPR1,XYLB,CHST11,ITFG1,MED13L,EVPL,ARID1B,RHBDD1,KIAA1958,ISPD,VAPB,CCDC124,ZCCHC7,SNX29,TRAPPC9,CRADD,SETD2,HAUS6,C11orf65,CORIN,AGAP1,CYB5B,DNAH14,VAC14,TBC1D2,GRIK4,ATXN7,BICD1,FAT1,SDCCAG8,EXOC4,SNX24,TMEM117,SIL1,CASS4,CDKAL1,PPP1R12B,KIAA1328,ARHGAP12,ZFP90,DDX10,TBCK,PDSS2,PRKAR2A,DMXL2,TCF12,USP7,CHMP2A,ASH1L,PCNT,SUCLG1,PAPD4,NTSR1,SSBP2,RADIL,URB1,GBF1,FDX1,ANKRD13A,JAG1,MPHOSPH10,NUP133,UBR1,SNTG2,MYH15,ZFP37,FHIT,ADCK4,MET,VCL,AUP1,SOBP,NARS2,RTN4RL2,PCGF3,AKAP8L,FAM172A,THSD4,MANBAL,MRRF,AKAP13,TPK1,BTBD11,SMAD3,ARMC4,RANBP2,CLEC16A,ITGA2,ATG7,SRFBP1,PUS1,SMG1,PARD3,TMCC1,DMGDH,SH2D3A,DYM,CMTM8,DBF4,CLSTN2,C14orf159,SEMA3E,CCDC7,PPP1R1C,RBM19,GFM2,ZNF594,PTPN2,SACS,CWC27,TMEM161A,SEC24C,DSG2,CD44,TTC17,LDLRAD3,DMRT1,HSD17B12,KDM6B,SLC6A16,ARNTL2,CRIM1,SCFD2,RAP1GDS1,FERMT2,C11orf49,PALLD,ZNF407,EIF5B,NAALADL2,PIK3CB,ARMC3,RERE,POLR3G,NOL10,SRBD1,SET,BCAS3,GLG1,PREPL,RPS6KC1,MMP16,MIPOL1,ZAK,SLC16A10,ZSWIM6 |
| 4.625e-10 | -21.49 | KEGG_AMINOACYL_TRNA_BIOSYNTHESIS | MSigDB lists | KEGG_AMINOACYL_TRNA_BIOSYNTHESIS | 41 | 22 | 17758 | 2279 |
CARS,NARS2,SARS,GARS,WARS2,NARS,LARS2,HARS,RARS2,AARS2,FARS2,VARS,MARS,AARS,TARS,YARS2,WARS,FARSA,RARS,EPRS,HARS2,YARS |
| 5.081e-10 | -21.40 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 16286 | 2159 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,C19orf70,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,NIT1,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 5.099e-10 | -21.40 | blood_vessel | COSMIC cancer mutations | blood_vessel | 2302 | 390 | 17775 | 2278 |
ARHGAP26,ADAM19,CNTNAP3,CACNA1H,SBF2,ENAH,CSPP1,LPIN1,SKI,TOM1L1,PCDH7,PDZD2,ZFHX3,ATP5G2,FAAH2,RABGAP1L,MAD1L1,ZNF148,ME1,AVEN,CNTNAP3B,SEH1L,NRAS,PTPRM,UPP1,KIF15,CUX1,RFX2,WDHD1,ABCC2,OSBPL1A,DOT1L,TRRAP,HSDL2,VPS13D,SEMA3C,GREB1L,RUNX1,NMD3,HERC2,IFT57,NHS,OPHN1,PIK3R4,PID1,CCDC47,PARN,ABCA7,SLC39A11,ANXA10,IGF2BP3,RBM20,PRKCE,UBE3A,DHX37,ASAP1,COPS3,VWDE,PIGG,MED24,IGF2BP1,MFAP2,FMNL2,SAMD3,SIK3,EXOSC2,STAG1,KCNQ3,PRIM2,PRDM16,RAPGEF4,RAP1GAP2,RYR2,ATAT1,PTPN12,USP10,PLCB1,ONECUT2,DYNC1H1,ZNF425,ASCC3,VPS13C,LRP1B,TASP1,KIDINS220,NME7,PDLIM1,TRAP1,PMEPA1,VCAN,ZZEF1,MED15,ZNF160,UMPS,NCOR1,MB21D2,ARHGAP10,COG5,RTTN,TBKBP1,ZNF516,LIN28B,PAFAH1B1,HFM1,VTI1A,MYH9,PTPRG,ST3GAL6,SLC25A44,RPGRIP1L,PAIP2,ZNF827,ABCA12,TBC1D22A,WAC,DTNBP1,SHF,NBEA,PNPLA4,DENND1A,ZCCHC14,MPP6,KMT2D,C1orf228,FAM111B,WDPCP,SLCO6A1,PCNXL2,SATB2,TTC28,TBC1D16,STK10,ERC1,FGFR1,PDE8B,HTR7,CAMK2D,CDC16,KDM4B,ASTN2,NSMCE2,ZNF236,WDR7,LARGE,ACP1,IFT140,CBWD1,FUS,MDN1,ANXA2,ANKS1A,MID1,COMMD10,BRAF,TTC27,TCF3,FARS2,RCAN1,RTN4,ATG2B,OPA1,RSRC1,REEP5,MBNL1,FAM8A1,ABL1,NPRL2,NEBL,CFDP1,RDX,ACTR3B,SOX6,PFKFB4,VPS37A,TTLL5,CLYBL,LDHA,PACS1,OASL,UBE2K,PDE3B,CASC1,RPA1,KLHL22,SRCAP,PXDN,ACOX1,SLCO5A1,PTPN4,MYOM2,NDUFS5,SORCS2,BRWD3,CORO2B,IMMP2L,NF1,RARS2,KIF5A,TFIP11,SLC25A21,ZNF107,SIRT2,FAM13A,COX10,EDC3,RTN1,ZNF804A,ANAPC1,THADA,JAZF1,MYH3,GPATCH1,POLR3B,PCOLCE2,CCDC121,CARM1,CEP128,VPS13B,DSC3,FLNC,DTNB,DEAF1,GPM6A,SKAP2,ITPA,CMIP,ANK2,COL4A3BP,KSR2,HDAC8,LAMA2,MTHFD1L,SERGEF,CHAF1A,TMEM132B,EPN2,HLCS,TP53BP1,DNAJC1,FAM114A2,CCDC146,CSMD3,ADAM9,ASB3,VIPR1,XYLB,CHST11,ITFG1,MED13L,EVPL,ARID1B,RHBDD1,KIAA1958,ISPD,VAPB,CCDC124,ZCCHC7,SNX29,TRAPPC9,CRADD,SETD2,HAUS6,C11orf65,CORIN,AGAP1,CYB5B,DNAH14,VAC14,TBC1D2,GRIK4,ATXN7,BICD1,FAT1,SDCCAG8,EXOC4,SNX24,TMEM117,SIL1,CASS4,CDKAL1,PPP1R12B,KIAA1328,ARHGAP12,ZFP90,DDX10,TBCK,PDSS2,PRKAR2A,DMXL2,TCF12,USP7,CHMP2A,ASH1L,PCNT,SUCLG1,PAPD4,NTSR1,SSBP2,RADIL,URB1,GBF1,FDX1,ANKRD13A,JAG1,MPHOSPH10,NUP133,UBR1,SNTG2,MYH15,ZFP37,FHIT,ADCK4,MET,VCL,AUP1,SOBP,NARS2,RTN4RL2,PCGF3,AKAP8L,FAM172A,THSD4,MANBAL,MRRF,AKAP13,TPK1,BTBD11,SMAD3,ARMC4,RANBP2,CLEC16A,ITGA2,ATG7,SRFBP1,PUS1,SMG1,PARD3,TMCC1,DMGDH,SH2D3A,DYM,CMTM8,DBF4,CLSTN2,C14orf159,SEMA3E,CCDC7,PPP1R1C,RBM19,GFM2,ZNF594,PTPN2,SACS,CWC27,TMEM161A,SEC24C,DSG2,CD44,TTC17,LDLRAD3,DMRT1,HSD17B12,KDM6B,SLC6A16,ARNTL2,CRIM1,SCFD2,RAP1GDS1,FERMT2,C11orf49,PALLD,ZNF407,EIF5B,NAALADL2,PIK3CB,ARMC3,RERE,POLR3G,NOL10,SRBD1,SET,BCAS3,GLG1,PREPL,RPS6KC1,MMP16,MIPOL1,ZAK,SLC16A10,ZSWIM6 |
| 5.379e-10 | -21.34 | WEI_MYCN_TARGETS_WITH_E_BOX | MSigDB lists | WEI_MYCN_TARGETS_WITH_E_BOX | 743 | 154 | 17758 | 2279 |
SRM,CUTC,MAP2K3,WNT2B,MRPS30,SRPRB,PHF5A,LONRF2,DHX33,UBAP2L,ME1,POLR3B,POLE3,TRIP13,SEH1L,TIMM50,ABCC4,ZNF680,C2orf76,TSN,TCEB3,PSMG1,HDAC8,ODC1,LSG1,MGST1,DOT1L,GEMIN5,GLS,HPRT1,HLCS,RIOK1,FBXO45,WDR75,C9orf78,OXNAD1,QSER1,TIMM10,YARS2,NAMPT,TOX4,DHX37,COPS3,TNPO3,COQ3,LPCAT1,TOMM34,PRPS1,SERBP1,RABEPK,EXOSC2,PRIM2,PPAT,SIGMAR1,HAUS6,MAP7D1,PLCB1,POP1,PWP1,ASCC3,SYNCRIP,VCAN,HK2,SLC16A1,UMPS,DDX10,HS2ST1,BCCIP,VMA21,SUCLG1,LIN28B,CCDC58,DDX18,URB2,KLHL18,SMARCA4,TMEM177,NUP43,TUBB6,FOSL2,HSPA1A,NDUFB3,RIOK2,FLAD1,RPP30,IDI1,MPHOSPH10,PPID,UCHL5,ETF1,LSM10,PRMT3,IPO11,SAP30,HN1,RFC3,SFXN4,PCMT1,NLN,DKC1,NUDT15,RAD54B,DCBLD2,BAZ1A,VDR,SLC39A14,DUS3L,TIMM17A,SRFBP1,ANXA2,SCARB1,PUS1,EIF2B3,NOLC1,XRCC4,FAHD1,YDJC,MCM10,TTC27,OPA1,PHLDA2,NEDD4,SLC25A20,DCTPP1,NOP16,TRIAP1,SELT,UPF2,POLR1B,LDLRAD3,SAMD4A,HNRNPM,PKNOX1,TOP1,MSX1,TMEM126B,KCNMA1,ZC3H18,ABCF2,ASAP3,SCFD2,APTX,EIF5B,SYMPK,NOP58,HSPA1B,MRPL36,NME1-NME2,POLE2,ZNF330,RNF138,EIF2S1,NFKBIB,XPO6 |
| 7.700e-10 | -20.98 | BILD_MYC_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_MYC_ONCOGENIC_SIGNATURE | 189 | 56 | 17758 | 2279 |
SRM,CGN,UTP14A,DDX18,WDR74,C10orf2,SESTD1,SLC6A8,NLE1,PCYOX1L,NOP56,FLAD1,ABL2,FARSA,ANAPC1,ZBED2,NOP16,ATIC,MYC,PCOLCE2,SPTAN1,RABEPK,METTL1,ARNTL2,DDX28,TUBA1A,OSBP2,MON1A,SFXN4,CDK4,GNL3,XPO5,BCS1L,NOL6,SCFD2,AKAP12,DKC1,LSG1,GEMIN5,PES1,DDAH2,MYBBP1A,AHNAK,FGFBP1,ERVMER34-1,ARNTL,HK2,PTRH2,ABCC3,RUNX1,NRP1,NOLC1,DDX10,GPATCH4,IPO4,NIT1 |
| 8.000e-10 | -20.95 | chromosome | cellular component | GO:0005694 | 848 | 169 | 17570 | 2233 |
THOC5,ATRX,PLRG1,FANCD2,NAT10,CSNK2A1,SIRT2,NUP160,BIRC2,SMARCB1,KANSL1,XRCC2,MAD1L1,PDS5B,RAN,POLE3,SEH1L,TMPO,HMBOX1,SETD1B,SIRT6,BAZ2A,CDK4,EHMT1,NOL6,SUMO3,WDHD1,HDAC8,HIST1H2BL,BRCA1,MCM2,CHAF1A,TRRAP,RAD18,HLCS,TP53BP1,NSMCE1,E2F4,RAD51B,EME1,CCNB1IP1,ZC3H8,DCTN3,EP400,TTN,MCM6,ANKRD17,DPF2,SIRT7,CENPB,CDC73,CHD5,TOX4,RNF40,ELL,INTS7,APLF,MCM5,MBD2,BANF1,BUD31,CTR9,TIMELESS,ICE2,NRIP1,TERF2,GATAD2B,WDR61,STAG1,PRIM2,POLA1,SETD2,LIG4,SMARCD3,ARID1A,PLCB1,TCF7L2,PHF6,EHMT2,PURB,HMBS,NCOR1,TCF12,ASH1L,PAFAH1B1,SMARCA4,NUP43,TNKS1BP1,PELP1,RING1,KDM1A,PHC2,TERF2IP,SLX4,MPHOSPH10,BCAS2,ACD,KDM2A,NUP133,UCHL5,RNF2,MSH4,SPIDR,HTRA2,CTC1,PRPF19,KAT8,RFC4,BRD4,RFC3,SETD7,ENC1,POLG2,PES1,SMAD3,BAZ1A,SMARCC1,KLF4,NSMCE2,H2AFX,PUS1,NFRKB,XRCC4,HMGA2,NIFK,ESCO1,MCM10,TCF3,H2AFJ,PPHLN1,MLH1,RBM19,CSNK1A1,HIST2H2AB,POGZ,NEDD4,SFR1,SNW1,POLR3D,SUV39H2,CFDP1,HIST2H3D,EXOSC4,TOP1,TRNP1,SMARCAD1,TOP3A,TEX14,SCMH1,RANGAP1,APTX,HIST1H4J,MEN1,FOXC1,ZRANB3,CENPP,POLR3G,RPA1,NSD1,POLE2,ZNF330,ORC5,MSH3,BCAS3,ATM,MBD6,KDM4C,IPO4,KAT6A |
| 8.384e-10 | -20.90 | bile_duct | COSMIC cancer mutations | bile_duct | 15891 | 2116 | 17775 | 2278 |
CDCP1,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,NARS2,RTN4RL2,NPW,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,PDS5B,LYRM5,HRG,AVEN,MSRB3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,CAD,DUS4L,UBR1,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,INTS12,C16orf58,MSH4,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERIN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|
| 8.384e-10 | -20.90 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15891 | 2116 | 17775 | 2278 |
CDCP1,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,NARS2,RTN4RL2,NPW,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,PDS5B,LYRM5,HRG,AVEN,MSRB3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,CAD,DUS4L,UBR1,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,INTS12,C16orf58,MSH4,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 9.200e-10 | -20.81 | cytosol | cellular component | GO:0005829 | 3220 | 515 | 17570 | 2233 |
ARHGAP26,DPH1,ACTG1,DCP1B,AARS2,MKS1,CHAC1,NT5C3A,NUP160,SYNJ1,LPAR3,NOS1AP,AMBRA1,TOM1L1,NEK6,SREBF2,PMAIP1,AP1M1,MAD1L1,PDS5B,FXN,CDK6,EIF4E3,UPP1,KIF15,C5AR1,MCL1,DDX3X,AHNAK,BDH2,FIS1,TPM1,RBP1,CARS,TNNC1,TRIO,PIK3R4,CLINT1,PARN,YARS2,SH2B3,CHN1,EIF2S2,APLF,ALKBH8,GEMIN4,PRMT5,MAP3K12,AGL,PABPC1,FMNL2,PPA1,MYB,PEA15,STAG1,MYO10,RB1CC1,PRDM16,EIF4A2,RYR2,ATAT1,SNAP25,IMPDH2,EVI5,TRIM37,ABCF1,NCDN,IRS1,DYNC1H1,KPNA1,GSTO2,RPL28,CNOT6,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,SGSM3,COG5,GALE,MAP2K5,PAFAH1B1,NPAS2,ATP6V1A,ACTR3,MYH9,NUP43,STAM,EEA1,HSPA1A,RPGRIP1L,SPG21,ABCA12,PYCRL,FMNL1,GSTA4,NT5C,CEP63,MGLL,MTHFD2L,LYST,GARS,EIF3J,ARHGEF10,NUDT15,MAT2A,FGFR1,PDE8B,CDC16,POLR3E,RPS6KB1,BAG1,MAPT,MORC2,SHQ1,ID2,AKT1S1,TRIM22,PSMF1,POLR3D,ACOT11,ARHGAP1,RPL22L1,SPTAN1,NUDC,CEP83,ARHGAP39,LDHA,NXN,PPIP5K2,PDE3B,UBC,TRIB3,RARS,STX1A,HERC1,IGBP1,MTMR1,DOCK6,ANAPC4,SRM,CUL7,BCAS4,CSNK2A1,FAM13A,SEC16A,BIRC2,MAP2K3,ABL2,AMPD3,COPS4,ARHGAP18,PHKA1,NCKIPSD,PPCDC,RAN,ZMYM2,MPST,CDC37,FLNC,FMNL3,RBCK1,PPARG,HARS,ANK2,CDK4,ATOX1,TSN,COL4A3BP,ATG12,ODC1,LSG1,PEX1,GLS,HPRT1,ZNF622,PPP3CC,CHMP4C,XYLB,CTU2,TTN,SARS,PGPEP1,FOXO1,SMAD7,ZFP36L1,RNF40,CEP290,PDE10A,NDRG4,SYNJ2,TRAPPC9,PAXBP1,OBSCN,TRAPPC6B,PGD,SPAG9,IRAK2,PPP1R12B,ARHGAP12,HMBS,NAPA,PRKAR2A,USP7,KCTD7,SART1,MPI,CYLD,PAPD4,SUCLG1,RPS29,SLC2A1,PPP2R2A,RIPK1,TNKS1BP1,CAD,IDI1,DUS4L,UBR1,NUP133,DNAJB6,IKBKB,ETF1,AHCYL1,PRMT3,CASP10,IPO11,SEC24A,ARHGAP17,EVL,TUBA1A,DDX41,NARS,C1QTNF1,VIM,AKAP13,NUP214,EIF3H,SMAD3,RANBP2,ATG7,EIF2B3,FAHD1,AP2S1,PARD3,MINK1,MAP3K13,AGO2,MAP1S,APRT,VARS,CSNK1A1,IQGAP2,ADH5,ANXA7,IFIT5,TPM4,SLC35G1,FERMT2,RAP1GDS1,ARHGEF12,RANGAP1,RHOT2,PIK3CB,POLR3A,CENPP,POLR3G,SET,EIF2S1,FNTB,PRDX6,PRKAB2,ENAH,GYG1,PRKCA,AARS,RAC3,LPIN1,GIPR,EXOC1,RPS16,ZFYVE28,DPH6,ME1,CEP135,SEH1L,CUX1,VSNL1,HSH2D,CLNS1A,DDAH2,SH3RF1,NRP1,BLMH,JUP,CDC42EP2,LARS2,OPHN1,TGFBR2,IGF2BP3,FKBP1A,PRKCE,PI4KB,ASAP1,ATIC,MYC,IGF2BP1,CNOT4,PRPS1,EXOSC2,SYNGAP1,PCCA,RAP1GAP2,RAPGEF4,RAP1B,PTPN12,PLCB1,MTR,CAT,SEC31A,EPRS,MTHFD2,SERF2,KIDINS220,HIF1A,UBAP1,NSF,SRP68,UMPS,CNDP2,MAP2K4,AMOTL1,UROD,AP1B1,PDE3A,FLNB,BLOC1S2,FLAD1,ASNS,SHC1,UCHL5,LPIN2,DTNBP1,NBEA,CMPK1,PREX1,DLG4,SERP1,ERC1,SNCA,CAMK2D,G6PD,DNAJA3,TRAF3,ANXA2,TBXA2R,XRCC4,PDCD11,MID1,BRAF,MRI1,NOL3,INPP1,FOXO3,NEDD4,ABL1,DCTPP1,PTRF,NISCH,UPF2,EXOSC4,DYNC2H1,MAP3K14,ERRFI1,LARP4B,PFKFB4,PXN,PSAT1,ADSL,PACS1,PTK2,OASL,APAF1,ADK,DDIT3,STK4,MVK,EIF3C,NF1,KIF5A,SIRT2,AHCYL2,EDC3,DST,ANAPC1,RAP1A,ATG3,ANAPC11,MYH3,ANAPC10,RELB,POLR3B,YARS,CARM1,PRKACB,SESN2,SKAP2,TXLNG,ITPA,GPCPD1,TMEM216,MINA,HDAC8,CAV1,MTHFD1L,SGK2,TCTN1,ARPC3,GEMIN5,RHOU,EIF4ENIF1,SUFU,HLCS,BBIP1,CRCP,CLU,TNRC6A,DCTN3,SEC24D,RHOBTB1,VTA1,UBXN1,SMG7,PHGDH,DDIT4,NAMPT,CEP164,BANF1,GLTP,HSD17B14,MTHFD1,HBG2,PDE4A,PPAT,XPO5,PSMA1,WWC1,BLOC1S4,UBE2E1,ISG15,EXOC6,BICD1,FSCN1,FDPS,SDCCAG8,EXOC4,HK2,RRAGA,PTRH2,PDE9A,AGO3,CHMP2A,SNX27,PCNT,PSTPIP2,MYO7A,FARSA,LYPLAL1,SOCS1,ADCK4,FHIT,VCL,HTRA2,S100A16,TPK1,WARS,PLIN2,KPNA3,DUS3L,ALAD,WDR73,ECHDC1,SMG1,DNAJC2,DNAJA4,SULT1C2,PDE4B,TKFC,IGF2BP2,PIP4K2A,SFI1,PRKCH,PEX7,GART,SEC24C,TANK,DCTN4,UTS2,AMOT,SULT4A1,MARS,ARHGAP32,MEN1,PDE2A,EIF5B,TARS,HSPA1B,MFN2,AGTPBP1,CUL2,NCBP2,PREPL,NFKBIB,POLR1C |
| 9.248e-10 | -20.80 | BENPORATH_NANOG_TARGETS | MSigDB lists | BENPORATH_NANOG_TARGETS | 942 | 185 | 17758 | 2279 |
FEM1C,TRIM16,CNTNAP3,POLR1A,TMEM109,HLTF,UBR5,SLC30A7,RAP1A,MARVELD2,METTL8,TRIML2,VPS52,JOSD1,CHD2,CDK6,LAMA4,HMBOX1,ATF4,HSPA5,NOL6,KIF15,WDHD1,CAV1,DCUN1D5,COTL1,SON,PEX1,OSBPL1A,GNAI1,MLLT10,CXADR,SKIL,TCF7L1,SUPT4H1,EIF4ENIF1,GATA6,SUFU,HSPBAP1,SEMA3C,RBP1,TNRC6A,EPM2AIP1,FOXO1,JUP,PRPF31,KHDRBS1,ZFP36L1,ZIC2,PRPF39,PHGDH,SLC1A1,ARID1B,IGF2BP3,RSPRY1,FAM192A,SLC7A11,SCAF1,VAPB,ANP32B,NOC3L,MAP3K12,LRP3,VOPP1,PEA15,KIAA1143,TLE3,EPS15L1,ARID5B,PSMA1,USP10,EIF2A,CPT1A,CYB5B,EHBP1,TCF7L2,PWP1,UBAP2,SPAG9,PALB2,NME7,FAT1,VCAN,FDPS,EXOC4,GPN1,TBL1X,NCOR1,DHCR7,USP7,AMOTL1,ID1,ZNF516,CYLD,ATP6V1A,DDX18,NPAS2,RBFOX2,KLHL18,RIPK1,PBX1,RNF24,SSBP2,GBF1,NDUFB3,FARSA,RRN3,KDM2A,ARMC6,NVL,PPFIBP1,INTS12,RNF2,ANO8,FHIT,SERPINH1,PERP,HN1,PRPF19,TLCD1,SEC24A,WDR36,MPP6,DDX41,R3HDM1,POU2F1,TMEM123,VIM,GALK2,GSTCD,SERP1,FGFR1,WARS,RAD54B,PLIN2,SMAD3,CDC16,KPNA3,CEBPZ,H2AFX,TSSC1,LARGE,ALKBH1,NOLC1,PPIL3,PKIB,DNAJC2,UTP14A,RFX1,DYM,H2AFJ,ID2,MLH1,TRIM22,FOXO3,BZW2,SFI1,PTPN2,POLR3D,GART,NEBL,NOP16,ARHGAP1,FBXO31,PNMA1,HSD17B12,SLC40A1,FGF2,SMARCAD1,FOXN3,ANKMY2,ABCF2,RANGAP1,DDX49,UBC,POLR3G,DKK1,ANXA1,INF2,SET,GLG1,TAF12,PREPL,MTMR1,KAT6A |
| 1.317e-09 | -20.45 | ribonucleoprotein complex biogenesis | biological process | GO:0022613 | 363 | 89 | 16441 | 2138 |
SART1,EIF3C,MRPL10,ISG20L2,NLE1,SBDS,EDC3,DENR,NOP56,METTL16,CHD7,RRN3,RPS16,MPHOSPH10,ERI1,NVL,ZNHIT6,RAN,UTP4,FTSJ3,SRPK2,PRPF19,SF3A1,WDR36,SNU13,PTBP2,SKIV2L2,EIF3J,NPM3,GNL3,NOL8,MINA,NOL6,METTL15,GNL1,DKC1,LSG1,CLNS1A,EIF3H,PES1,DDX3X,GEMIN5,ZNF622,LSM14A,LUC7L3,SRFBP1,HEATR1,MDN1,PDCD11,NOCT,NOLC1,NMD3,SHQ1,DROSHA,UTP14A,PRPF31,AGO2,SF3A3,PRPF39,NOL3,MBNL1,MRPS11,DDX56,NOP16,ATXN2,DDX31,CELF1,EXOSC4,GEMIN4,ERI3,PRMT5,FBL,DIS3L2,NOM1,SCAF11,EXOSC2,DDX28,WBSCR22,UTP15,BMS1,EIF2A,NOP58,ABCF1,MRPL36,DYNC1H1,TSR1,BICD1,NCBP2,AGO3 |
| 1.455e-09 | -20.35 | nucleotide binding | molecular function | GO:0000166 | 2291 | 393 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,NT5C3A,PRKCA,SYNJ1,RAC3,AARS,PABPC4,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,ACADS,NRAS,SETD1B,GNL3,NOL8,KIF15,ABCC2,MCM2,DDX60,RBM28,GNAI1,DDX3X,BDH2,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,SIRT7,AK6,PIK3R4,TGFBR2,PARN,CHD5,YARS2,ABCA7,IGF2BP3,RBM20,PRKCE,DDX56,PI4KB,DHX37,APLF,MCM5,IGF2BP1,CNOT4,MAP3K12,PRPS1,PABPC1,HMGCR,SIK3,DDX28,MYO10,POLA1,PCCA,EIF4A2,RAPGEF4,IDH3G,TYW1,RAP1B,IMPDH2,ABCF1,ATP9B,CAT,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,LEMD3,CDK9,SPEN,D2HGDH,RIOK3,GPN1,SQLE,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,PABPC1L,SAFB2,LTB4R,CBWD5,HNRNPA3,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,DECR1,PRKD3,ASNS,ABCA12,GLYR1,CLCN6,NT5C,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,FGFR1,DHX57,CAMK2D,HIPK2,G6PD,DNAJA3,ARL13B,CBWD1,TRMT2A,RPS6KB1,FUS,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,DCTPP1,TTLL11,ABL1,CBWD6,GATC,HARS2,CELF1,DYNC2H1,MAP3K14,NT5M,ACTR3B,HNRNPM,CLK2,NAV3,PFKFB4,TTLL5,DDX24,LDHA,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,ETFDH,SRCAP,RARS,DDX50,HELZ,ACOX1,HNRNPH3,ORC5,ATM,APAF1,ADK,STK4,MVK,RBM33,ATRX,RARS2,PPARGC1B,KIF5A,TRPM6,CSNK2A1,SIRT2,STK33,HNRNPLL,SCAF8,MAP2K3,SRPRB,ABL2,RAP1A,SRSF2,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,TRIP13,PRKACB,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,SIRT6,ITPA,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HPRT1,HLCS,CHD3,FAM114A2,ARL4A,EEFSEC,RAD51B,CRCP,ABCC3,MAGI1,TNRC6A,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,RHOBTB1,TAF1,HSD17B10,PHGDH,DNAH1,ABCA5,MBD2,PDE10A,SYNJ2,ALDH18A1,GMDS,N4BP2,NT5E,MTHFD1,MSI2,WARS2,CAMKK2,PDE4A,TRA2A,BCS1L,LIG4,OBSCN,AGAP1,ACOXL,UBE2E1,DNAH14,PGD,ATAD5,SYNCRIP,DNAH17,IRAK2,HK2,RRAGA,SIL1,DDX10,TBCK,BRSK2,PRKAR2A,SUCLG1,PAPD4,RBFOX2,MYO7A,SMARCA4,RIPK1,DHX35,DDX60L,KDM1A,MIEF1,RIOK2,CAD,FARSA,ZBTB21,DUS4L,NVL,CBR4,RPS6KL1,IKBKB,MYH15,FHIT,MET,SKIV2L,NARS2,ACSL5,TUBA1A,PTBP2,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,ATP5D,WARS,TPK1,RAD54B,DUS3L,HNRNPR,SEPT5,SMG1,TNIK,BCKDK,NIFK,MINK1,DNAJA4,MAP3K13,ARL15,CAMK1,PDE4B,TKFC,ARFIP2,APRT,IGF2BP2,VARS,RBM19,CSNK1A1,ENOX1,RMI1,PIP4K2A,MFHAS1,GFM2,PRKCH,NDUFV1,GART,DDX31,PCK2,MICAL3,RPS6KB2,GPHN,PSPC1,SMARCAD1,ABCF2,DHX34,TEX14,MARS,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,NCBP2,RBM26,RPS6KC1,ZAK,KIF1B |
| 1.539e-09 | -20.29 | nucleoside phosphate binding | molecular function | GO:1901265 | 2292 | 393 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,NT5C3A,PRKCA,SYNJ1,RAC3,AARS,PABPC4,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,ACADS,NRAS,SETD1B,GNL3,NOL8,KIF15,ABCC2,MCM2,DDX60,RBM28,GNAI1,DDX3X,BDH2,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,SIRT7,AK6,PIK3R4,TGFBR2,PARN,CHD5,YARS2,ABCA7,IGF2BP3,RBM20,PRKCE,DDX56,PI4KB,DHX37,APLF,MCM5,IGF2BP1,CNOT4,MAP3K12,PRPS1,PABPC1,HMGCR,SIK3,DDX28,MYO10,POLA1,PCCA,EIF4A2,RAPGEF4,IDH3G,TYW1,RAP1B,IMPDH2,ABCF1,ATP9B,CAT,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,LEMD3,CDK9,SPEN,D2HGDH,RIOK3,GPN1,SQLE,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,PABPC1L,SAFB2,LTB4R,CBWD5,HNRNPA3,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,DECR1,PRKD3,ASNS,ABCA12,GLYR1,CLCN6,NT5C,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,FGFR1,DHX57,CAMK2D,HIPK2,G6PD,DNAJA3,ARL13B,CBWD1,TRMT2A,RPS6KB1,FUS,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,DCTPP1,TTLL11,ABL1,CBWD6,GATC,HARS2,CELF1,DYNC2H1,MAP3K14,NT5M,ACTR3B,HNRNPM,CLK2,NAV3,PFKFB4,TTLL5,DDX24,LDHA,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,ETFDH,SRCAP,RARS,DDX50,HELZ,ACOX1,HNRNPH3,ORC5,ATM,APAF1,ADK,STK4,MVK,RBM33,ATRX,RARS2,PPARGC1B,KIF5A,TRPM6,CSNK2A1,SIRT2,STK33,HNRNPLL,SCAF8,MAP2K3,SRPRB,ABL2,RAP1A,SRSF2,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,TRIP13,PRKACB,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,SIRT6,ITPA,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HPRT1,HLCS,CHD3,FAM114A2,ARL4A,EEFSEC,RAD51B,CRCP,ABCC3,MAGI1,TNRC6A,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,RHOBTB1,TAF1,HSD17B10,PHGDH,DNAH1,ABCA5,MBD2,PDE10A,SYNJ2,ALDH18A1,GMDS,N4BP2,NT5E,MTHFD1,MSI2,WARS2,CAMKK2,PDE4A,TRA2A,BCS1L,LIG4,OBSCN,AGAP1,ACOXL,UBE2E1,DNAH14,PGD,ATAD5,SYNCRIP,DNAH17,IRAK2,HK2,RRAGA,SIL1,DDX10,TBCK,BRSK2,PRKAR2A,SUCLG1,PAPD4,RBFOX2,MYO7A,SMARCA4,RIPK1,DHX35,DDX60L,KDM1A,MIEF1,RIOK2,CAD,FARSA,ZBTB21,DUS4L,NVL,CBR4,RPS6KL1,IKBKB,MYH15,FHIT,MET,SKIV2L,NARS2,ACSL5,TUBA1A,PTBP2,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,ATP5D,WARS,TPK1,RAD54B,DUS3L,HNRNPR,SEPT5,SMG1,TNIK,BCKDK,NIFK,MINK1,DNAJA4,MAP3K13,ARL15,CAMK1,PDE4B,TKFC,ARFIP2,APRT,IGF2BP2,VARS,RBM19,CSNK1A1,ENOX1,RMI1,PIP4K2A,MFHAS1,GFM2,PRKCH,NDUFV1,GART,DDX31,PCK2,MICAL3,RPS6KB2,GPHN,PSPC1,SMARCAD1,ABCF2,DHX34,TEX14,MARS,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,NCBP2,RBM26,RPS6KC1,ZAK,KIF1B |
| 1.569e-09 | -20.27 | Ribosome biogenesis in eukaryotes | KEGG pathways | hsa03008 | 78 | 31 | 6908 | 881 |
WDR75,SNU13,WDR36,DROSHA,UTP14A,GNL3,AK6,UTP15,NOL6,NAT10,CSNK2A1,BMS1,POP5,DKC1,RBM28,NOP58,LSG1,SBDS,RIOK2,NOP56,RPP30,POP1,MPHOSPH10,NVL,RIOK1,HEATR1,MDN1,RAN,FBL,NMD3,UTP4 |
| 1.569e-09 | -20.27 | Ribosome biogenesis in eukaryotes | KEGG pathways | ko03008 | 78 | 31 | 6908 | 881 |
WDR75,SNU13,WDR36,DROSHA,UTP14A,GNL3,AK6,UTP15,NOL6,NAT10,CSNK2A1,BMS1,POP5,DKC1,RBM28,NOP58,LSG1,SBDS,RIOK2,NOP56,RPP30,POP1,MPHOSPH10,NVL,RIOK1,HEATR1,MDN1,RAN,FBL,NMD3,UTP4 |
| 1.667e-09 | -20.21 | FBL (fibrillarin) | protein interactions | 2091 | 223 | 66 | 16036 | 2270 |
CUL7,LIN28B,DDX18,RSL1D1,PABPC4,NOP56,TERF2IP,MPHOSPH10,GLYR1,RNF2,PXK,SRRM2,PRMT3,UTP4,FTSJ3,WDR36,SNU13,GNL3,NOL8,NOL6,DKC1,PUM3,PES1,HNRNPR,COPS5,SRFBP1,RIOK1,NOLC1,BMI1,PDCD11,NIFK,WDR75,FN1,PRPF31,SIRT7,TCF3,RBM19,RSPRY1,DDX56,EIF2S2,MYC,BANF1,NOC3L,GEMIN4,GTF3C3,PRMT5,MAP3K14,ZNF629,NOM1,TOP1,TERF2,RANBP6,DDX24,UTP15,KLF6,NOP58,PHF6,UBC,RPA1,PWP1,POP1,KPNA1,RIOK3,ZNF430,GPATCH4,LRRC41 |
| 1.692e-09 | -20.20 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5361 | 810 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,CSPP1,HLTF,SLC6A8,NUP160,SYNJ1,NOS1AP,SKI,ZNF37A,PCDH7,MMP7,NEK6,ZFHX3,PMAIP1,RASSF3,FAAH2,RABGAP1L,MAD1L1,KDM5C,FXN,AVEN,SRRM2,CDK6,PPM1K,CCDC57,NRAS,PTPRM,UPP1,MSRB3,AKAP12,MCL1,PLEKHM3,C10orf76,MCM2,ZNF197,DDX3X,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,EP400,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,DHX37,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,WDR60,ANP32B,GEMIN4,ZNF518B,MAP3K12,MYB,HMGCR,KLRD1,PEA15,ZNF675,GTF2H3,IFRD1,STAG1,PRDM16,ARID5B,EPS15L1,EIF4A2,RYR2,USP10,SMARCD3,IMPDH2,SNAP25,TRIM37,USP46,ABCF1,IRS1,VPS13C,LRP1B,KPNA1,TRAP1,SURF1,GPN1,WDR33,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,SAFB2,EEA1,HSPA1A,MCM9,RPP30,PRKD3,BCAS2,ACD,FMNL1,MMP14,MSH4,TRMT12,PMS1,GARS,KMT2D,STAMBP,NPM3,ARHGEF10,SLCO6A1,FAM171A2,ADAM32,PCNXL2,MEF2D,KCNH3,FKBP3,FGFR1,PES1,TAF2,GNG2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,ASTN2,HIPK2,PEMT,WDR7,RPS6KB1,FUS,BRCC3,LAMA5,BAG1,RAB30,TRIM36,HMGA2,XPC,SESTD1,TRAK1,ID2,GAS6,IP6K2,POM121,TADA3,SUV39H2,GATC,TAF3,NOP16,UNC13A,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,LDHA,IL6R,FOXC1,DDX49,ANXA1,RPA1,OXSR1,TRIB3,NSD1,PXDN,POLE2,HERC1,SLCO5A1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,RBM33,TRIM16,WDR13,PPARGC1B,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,DHX33,PHKA1,XRCC2,NCKIPSD,ANKRD11,RAN,POLE3,ETV1,ZMYM2,PTPRK,VPS13B,CHD9,FMNL3,MIOS,CDK4,HSPA5,TSN,COL4A3BP,GMFB,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,EEFSEC,ARL4A,E2F4,PER1,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,AOC3,MCM6,PGPEP1,FOXO1,CLK1,ITFG1,NKD2,SMAD7,LAMTOR3,MEX3A,MAPK8IP3,HSD17B10,HES6,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,CRADD,USP49,SETD2,UTP15,OBSCN,MEX3B,ZNFX1,NR2F1,VAC14,GRIK4,SPAG9,SYNCRIP,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,BCCIP,USP7,SART1,ID1,SUCLG1,ARID2,NTSR1,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,RADIL,PPP1R9A,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,HIBCH,CORO1A,AHCYL1,IPO11,CASP10,KDM3B,SKIV2L,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,SIX5,KLF4,ABHD3,ITGA2,PUS1,MED20,SEPT5,MUTYH,PARD3,ZNF507,MCM10,AUH,MAP3K13,APRT,VARS,RBM19,FOXP1,CSNK1A1,IQGAP2,PTPN2,ADH5,FAM50A,SACS,ANXA7,SURF2,DDX31,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,ABCF2,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ARMC3,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,KIF1B,MYCBP2,POLB,CUL4A,PRKAB2,TNFRSF21,ENAH,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,MGA,SUCLG2,ME1,CHD2,SPAG6,FAM127A,SETD1B,GNG7,TCEB3,ZDHHC14,DENND4A,PLCXD2,GZF1,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,IFT57,DROSHA,JUP,EGR1,ANKRD17,LARS2,ST6GAL1,CENPB,OPHN1,GTF2IRD1,SSR4,TGFBR2,PDCD5,CHD5,ANXA10,PRKCE,FKBP1A,NAV1,HR,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,SLC16A9,SAMD13,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,SIK3,DDX28,PRIM2,ANAPC13,IFNGR2,SYNGAP1,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,EHBP1,PHF6,DAGLA,CAT,HIF1A,PMEPA1,VCAN,SPEN,BIVM,RIOK3,PEX13,UMPS,C7orf50,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,BIRC6,URB2,C1QTNF7,PTPRG,FLNB,IGSF1,RING1,PHC2,NUBPL,FLAD1,TERF2IP,ASNS,SLX4,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,BRD4,RFC3,PDK1,PREX1,LRRC8A,SATB2,POLG2,STK10,ERC1,HSD3B7,DHX57,BAZ1A,HTR7,CAMK2D,SMARCC1,DNAJA3,G6PD,FTSJ1,H2AFX,ALKBH1,TRMT2A,TRAF3,MDN1,ANXA2,PDCD11,XRCC4,NOLC1,MID1,NCOR2,SSH2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,DNAJC22,NOL3,IKBKAP,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,COPS7B,NLGN3,S100A14,PLEKHG4,NAV3,CLK2,TMC7,PXN,APEX1,FZD3,KCNMA1,ADSL,FBXO21,ORC5,STX18,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,LRRC41,PIGM,PHF3,NF1,ATRX,RARS2,PTPRA,FANCD2,TRPM6,PLOD1,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,RTN1,ZNF804A,ANAPC1,RAP1A,THADA,LONRF2,JAZF1,ANAPC11,ANAPC10,RELB,KIAA0922,SLC27A5,OGG1,TRIM14,PRKACB,CEP128,SRPK2,TNK2,SESN2,TRIM13,FBXW4,TXLNG,ITPA,SIRT6,ARRDC3,GPCPD1,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,SOX4,SERGEF,TAF9B,UBTF,GEMIN5,RHOU,PAF1,DNAJC1,FAM114A2,PQBP1,CSMD3,ASB3,EME1,CLU,ZC3H8,COPS6,MTCH1,SLC12A7,FBXO45,AK2,PIGN,RHOBTB1,TAF1,PCSK7,MED13L,SMG7,QSER1,XPO7,ETFB,DDIT4,RNF141,ELL,SIPA1L3,ATXN2,GLTP,AKAP11,N4BP2,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,SYT1,DNAH14,UBE2E1,ISG15,KIAA0355,FAT1,HK2,SLC16A1,KIAA1328,TBL1X,TBCK,FNBP1L,ZBTB24,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,COBLL1,PBX1,GBF1,DHX35,RIOK2,BRE,SOCS1,CCDC50,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,MET,ITGAX,GNG5,MOSPD1,TMLHE,NARS2,PARP2,METTL2A,DKC1,UBR4,RAB10,RAD54B,WARS,ARMC4,ALAD,DUS3L,IKZF4,KPNA3,HNRNPR,COPS5,DUSP19,FKBP5,SCARB1,TMEM101,RNF130,HEATR1,USP11,SMG1,DNAJC2,TNIK,BCKDK,DNAJA4,SH2D3A,C17orf80,SUPT6H,CAMK1,DYM,PDE4B,DBF4,CLSTN2,LETMD1,MED18,IGF2BP2,ATF7IP,PPP1R1C,FAM49A,PIP4K2A,IL17RE,PRKCH,CTNNBL1,TANK,KDELC1,SHMT2,ERI3,AMOT,RPS6KB2,TOP1,KDM6B,MSX1,DNMBP,IL11RA,GPHN,FGF2,CRIM1,KDM5A,TEAD1,MARS,ARHGAP32,MEN1,TMEM187,NAPEPLD,ZNF708,ALG5,DAGLB,GADD45A,AGTPBP1,CUL2,PREPL,NFKBIB,MMP16,ZAK |
| 1.692e-09 | -20.20 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5361 | 810 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,CSPP1,HLTF,SLC6A8,NUP160,SYNJ1,NOS1AP,SKI,ZNF37A,PCDH7,MMP7,NEK6,ZFHX3,PMAIP1,RASSF3,FAAH2,RABGAP1L,MAD1L1,KDM5C,FXN,AVEN,SRRM2,CDK6,PPM1K,CCDC57,NRAS,PTPRM,UPP1,MSRB3,AKAP12,MCL1,PLEKHM3,C10orf76,MCM2,ZNF197,DDX3X,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,EP400,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,DHX37,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,WDR60,ANP32B,GEMIN4,ZNF518B,MAP3K12,MYB,HMGCR,KLRD1,PEA15,ZNF675,GTF2H3,IFRD1,STAG1,PRDM16,ARID5B,EPS15L1,EIF4A2,RYR2,USP10,SMARCD3,IMPDH2,SNAP25,TRIM37,USP46,ABCF1,IRS1,VPS13C,LRP1B,KPNA1,TRAP1,SURF1,GPN1,WDR33,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,SAFB2,EEA1,HSPA1A,MCM9,RPP30,PRKD3,BCAS2,ACD,FMNL1,MMP14,MSH4,TRMT12,PMS1,GARS,KMT2D,STAMBP,NPM3,ARHGEF10,SLCO6A1,FAM171A2,ADAM32,PCNXL2,MEF2D,KCNH3,FKBP3,FGFR1,PES1,TAF2,GNG2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,ASTN2,HIPK2,PEMT,WDR7,RPS6KB1,FUS,BRCC3,LAMA5,BAG1,RAB30,TRIM36,HMGA2,XPC,SESTD1,TRAK1,ID2,GAS6,IP6K2,POM121,TADA3,SUV39H2,GATC,TAF3,NOP16,UNC13A,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,LDHA,IL6R,FOXC1,DDX49,ANXA1,RPA1,OXSR1,TRIB3,NSD1,PXDN,POLE2,HERC1,SLCO5A1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,RBM33,TRIM16,WDR13,PPARGC1B,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,DHX33,PHKA1,XRCC2,NCKIPSD,ANKRD11,RAN,POLE3,ETV1,ZMYM2,PTPRK,VPS13B,CHD9,FMNL3,MIOS,CDK4,HSPA5,TSN,COL4A3BP,GMFB,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,EEFSEC,ARL4A,E2F4,PER1,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,AOC3,MCM6,PGPEP1,FOXO1,CLK1,ITFG1,NKD2,SMAD7,LAMTOR3,MEX3A,MAPK8IP3,HSD17B10,HES6,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,CRADD,USP49,SETD2,UTP15,OBSCN,MEX3B,ZNFX1,NR2F1,VAC14,GRIK4,SPAG9,SYNCRIP,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,BCCIP,USP7,SART1,ID1,SUCLG1,ARID2,NTSR1,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,RADIL,PPP1R9A,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,HIBCH,CORO1A,AHCYL1,IPO11,CASP10,KDM3B,SKIV2L,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,SIX5,KLF4,ABHD3,ITGA2,PUS1,MED20,SEPT5,MUTYH,PARD3,ZNF507,MCM10,AUH,MAP3K13,APRT,VARS,RBM19,FOXP1,CSNK1A1,IQGAP2,PTPN2,ADH5,FAM50A,SACS,ANXA7,SURF2,DDX31,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,ABCF2,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ARMC3,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,KIF1B,MYCBP2,POLB,CUL4A,PRKAB2,TNFRSF21,ENAH,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,MGA,SUCLG2,ME1,CHD2,SPAG6,FAM127A,SETD1B,GNG7,TCEB3,ZDHHC14,DENND4A,PLCXD2,GZF1,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,IFT57,DROSHA,JUP,EGR1,ANKRD17,LARS2,ST6GAL1,CENPB,OPHN1,GTF2IRD1,SSR4,TGFBR2,PDCD5,CHD5,ANXA10,PRKCE,FKBP1A,NAV1,HR,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,SLC16A9,SAMD13,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,SIK3,DDX28,PRIM2,ANAPC13,IFNGR2,SYNGAP1,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,EHBP1,PHF6,DAGLA,CAT,HIF1A,PMEPA1,VCAN,SPEN,BIVM,RIOK3,PEX13,UMPS,C7orf50,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,BIRC6,URB2,C1QTNF7,PTPRG,FLNB,IGSF1,RING1,PHC2,NUBPL,FLAD1,TERF2IP,ASNS,SLX4,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,BRD4,RFC3,PDK1,PREX1,LRRC8A,SATB2,POLG2,STK10,ERC1,HSD3B7,DHX57,BAZ1A,HTR7,CAMK2D,SMARCC1,DNAJA3,G6PD,FTSJ1,H2AFX,ALKBH1,TRMT2A,TRAF3,MDN1,ANXA2,PDCD11,XRCC4,NOLC1,MID1,NCOR2,SSH2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,DNAJC22,NOL3,IKBKAP,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,COPS7B,NLGN3,S100A14,PLEKHG4,NAV3,CLK2,TMC7,PXN,APEX1,FZD3,KCNMA1,ADSL,FBXO21,ORC5,STX18,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,LRRC41,PIGM,PHF3,NF1,ATRX,RARS2,PTPRA,FANCD2,TRPM6,PLOD1,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,RTN1,ZNF804A,ANAPC1,RAP1A,THADA,LONRF2,JAZF1,ANAPC11,ANAPC10,RELB,KIAA0922,SLC27A5,OGG1,TRIM14,PRKACB,CEP128,SRPK2,TNK2,SESN2,TRIM13,FBXW4,TXLNG,ITPA,SIRT6,ARRDC3,GPCPD1,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,SOX4,SERGEF,TAF9B,UBTF,GEMIN5,RHOU,PAF1,DNAJC1,FAM114A2,PQBP1,CSMD3,ASB3,EME1,CLU,ZC3H8,COPS6,MTCH1,SLC12A7,FBXO45,AK2,PIGN,RHOBTB1,TAF1,PCSK7,MED13L,SMG7,QSER1,XPO7,ETFB,DDIT4,RNF141,ELL,SIPA1L3,ATXN2,GLTP,AKAP11,N4BP2,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,SYT1,DNAH14,UBE2E1,ISG15,KIAA0355,FAT1,HK2,SLC16A1,KIAA1328,TBL1X,TBCK,FNBP1L,ZBTB24,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,COBLL1,PBX1,GBF1,DHX35,RIOK2,BRE,SOCS1,CCDC50,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,MET,ITGAX,GNG5,MOSPD1,TMLHE,NARS2,PARP2,METTL2A,DKC1,UBR4,RAB10,RAD54B,WARS,ARMC4,ALAD,DUS3L,IKZF4,KPNA3,HNRNPR,COPS5,DUSP19,FKBP5,SCARB1,TMEM101,RNF130,HEATR1,USP11,SMG1,DNAJC2,TNIK,BCKDK,DNAJA4,SH2D3A,C17orf80,SUPT6H,CAMK1,DYM,PDE4B,DBF4,CLSTN2,LETMD1,MED18,IGF2BP2,ATF7IP,PPP1R1C,FAM49A,PIP4K2A,IL17RE,PRKCH,CTNNBL1,TANK,KDELC1,SHMT2,ERI3,AMOT,RPS6KB2,TOP1,KDM6B,MSX1,DNMBP,IL11RA,GPHN,FGF2,CRIM1,KDM5A,TEAD1,MARS,ARHGAP32,MEN1,TMEM187,NAPEPLD,ZNF708,ALG5,DAGLB,GADD45A,AGTPBP1,CUL2,PREPL,NFKBIB,MMP16,ZAK |
| 1.938e-09 | -20.06 | tRNA aminoacylation | biological process | GO:0043039 | 50 | 24 | 16441 | 2138 |
CARS,NARS2,SARS,WARS2,GARS,NARS,LARS2,HARS,RARS2,AARS2,FARS2,VARS,MARS,AARS,TARS,YARS2,WARS,FARSA,RARS,EPRS,GATC,HARS2,YARS,PPA1 |
| 1.938e-09 | -20.06 | amino acid activation | biological process | GO:0043038 | 50 | 24 | 16441 | 2138 |
CARS,NARS2,SARS,WARS2,GARS,NARS,LARS2,HARS,RARS2,AARS2,FARS2,VARS,MARS,AARS,TARS,YARS2,WARS,FARSA,RARS,EPRS,GATC,HARS2,YARS,PPA1 |
| 2.026e-09 | -20.02 | oesophagus-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-carcinoma-adenocarcinoma | 13776 | 1873 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,MPV17,RIOK1,RUNX1,VASH2,ZNF532,SLC25A26,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,ZNF675,IFRD1,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,FAM122B,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,RPGRIP1L,NDUFB3,CD96,ESAM,ZSWIM7,TBC1D22A,SETD5,WAC,CLCN6,C16orf58,INTS12,MSH4,PEG10,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,EIF3J,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,KCNH3,SLC35D1,DSP,VPS53,MAT2A,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,RPS6KB1,CEP170,METTL2B,CATSPERG,MAPT,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,RNASEH2B,PSMF1,SNW1,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,RPL22L1,SPTAN1,TTPAL,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,SORCS2,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,AMPD3,ECM1,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,LAMA2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,C1orf122,BSN,DYRK1B,TCF7L1,LSS,CHD3,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,FOXO1,CLK1,ITFG1,NKD2,SMAD7,MAPK8IP3,FAN1,ZIC2,LYRM2,ARID1B,SUB1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CCDC167,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,NDUFAF2,NTSR1,SLC2A1,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,KIRREL2,RAB7A,ANKRD33B,VIM,NHSL1,EIF3H,EXO1,LMBR1L,KLF4,ATG7,INTS9,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,HM13,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,POGZ,ANKRD54,SLC25A20,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,SMARCAD1,ABCF2,KRTCAP3,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,LUC7L3,CFD,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,C9orf78,JUP,LARS2,ST6GAL1,DLGAP4,CENPB,TATDN3,PDCD5,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,MFAP2,CAV2,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,ARID1A,TPRA1,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,CPT1C,HS2ST1,SYT17,BIRC6,UROD,KIAA0232,TMEM104,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,MBTD1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,PHLDA2,ABL1,NEBL,DYNC2H1,CELF1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,TTLL5,PSAT1,ZFYVE1,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,GUF1,SLC23A2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,IPO4,IMMP2L,PIGM,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,MINA,KSR2,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,ELL,HVCN1,ZNF354A,ISPD,CCDC124,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,HBG2,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,CORIN,SYT1,AGAP1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,TBCK,PDE9A,N4BP2L2,DMXL2,TCF12,CHMP2A,FEZ2,TNXB,SMARCA4,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,MPHOSPH10,NVL,SNTG2,FHIT,ITGAX,VCL,TMEM120B,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,ANTXR2,PRAME,GRHL3,ATXN1,MRRF,METTL15,EDEM2,UBR4,S100A16,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,DYM,KLC4,CMTM8,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,TMEM99,LDLRAD3,ERI3,PKNOX1,MICAL3,TOP1,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,NAALADL2,ZNF221,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,ANKRD30BL,VPS37B,POLR1C,NFKBIB,ZSWIM6,GNB3,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,AKAP12,PLEKHM3,MCL1,DCUN1D5,C10orf76,RBM28,DLEU1,BRCA2,SUPT4H1,ZNF266,TMEM139,MEF2C,TNNC1,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,ACTR3,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,GSTA4,CEP63,PERP,MALL,GARS,KRT7,STAMBP,FAM111B,NPM3,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,FUS,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,SF3A3,WDR37,AKT1S1,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,GATC,PVRL3,ACAP3,ARHGAP1,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,ETFDH,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,STX1A,ARID3B,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,NUDT22,DOCK6,CORO2B,ANAPC4,SRM,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,UBAP2L,ZNF85,ETV1,MPST,PTPRK,SF3A1,TMPO,METTL1,FLNC,CHD9,ZNF124,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,MSRA,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,ITPRIP,MEX3A,HES6,TRIM15,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,SYNCRIP,PALB2,SNAP23,DNAH17,PPP1R12B,ZNF430,ARHGAP12,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,GPR143,RSL1D1,LPCAT3,ZNF83,DENR,CAD,UBR1,ARMC5,FSIP2,DNAJB6,ZDHHC6,C15orf40,HIRIP3,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,MANBAL,TMEM123,SLC35F2,AKAP13,NUP214,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,NFASC,ZNF18,PUS1,ZNF589,PPIL3,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,MAP1S,C14orf159,ARFIP2,ZNF346,CSNK1A1,BZW2,ZNF594,IQGAP2,PTPN2,SACS,ANXA7,CWC27,IFIT5,PRICKLE2,DDX31,SELT,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,GINS3,ZMYM5,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,CHCHD6,TMEM175,PIK3CB,ARMC3,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,GPC2,SRBD1,ZBTB8OS,ADAT2,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,POLB,CGN,PRDX6,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,MEIS3,CEP135,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,CUX1,SEMA3F,FOXRED1,SAP30BP,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,ASAP1,COPS3,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,KIAA0586,PTPN12,TTYH2,RABAC1,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,PMEPA1,SRRD,NSF,ZZEF1,D2HGDH,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,URB2,RIBC2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,AP1B1,SLC25A44,FOSL2,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,HTR7,DNAJA3,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,NEDD4,MAD2L2,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,C19orf43,FZD3,KCNMA1,TBRG4,APTX,OASL,MMAA,NOP58,ECH1,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,STX18,RNF138,MYOM2,PGAM5,BRWD3,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,NDUFA6,CCDC121,TRIM14,TRIP13,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,TRIM13,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,MKL2,BBIP1,ABCC3,GALNT10,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,CEP164,TOX4,SIPA1L3,ATXN2,BUD31,SEMA3D,CCDC112,GLTP,NRIP1,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,PTRH2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMEM14C,HTRA2,TMLHE,HN1,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,PUSL1,RAB10,TPK1,WARS,RAD54B,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SH2D3A,C17orf80,DBF4,NSUN6,CLSTN2,PPHLN1,CCDC7,PPP1R1C,MFSD10,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,TTC17,AMOT,DMRT1,PAQR6,MSX1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,ZNF330,CUL2,NCBP2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10 |
| 2.340e-09 | -19.87 | aminoacyl-tRNA ligase activity | molecular function | GO:0004812 | 43 | 22 | 16491 | 2164 |
CARS,NARS2,SARS,GARS,WARS2,NARS,HARS,LARS2,RARS2,AARS2,FARS2,MARS,VARS,AARS,TARS,YARS2,WARS,FARSA,EPRS,RARS,HARS2,YARS |
| 2.340e-09 | -19.87 | ligase activity, forming aminoacyl-tRNA and related compounds | molecular function | GO:0016876 | 43 | 22 | 16491 | 2164 |
CARS,NARS2,SARS,GARS,WARS2,NARS,HARS,LARS2,RARS2,AARS2,FARS2,MARS,VARS,AARS,TARS,YARS2,WARS,FARSA,EPRS,RARS,HARS2,YARS |
| 2.340e-09 | -19.87 | ligase activity, forming carbon-oxygen bonds | molecular function | GO:0016875 | 43 | 22 | 16491 | 2164 |
CARS,NARS2,SARS,GARS,WARS2,NARS,HARS,LARS2,RARS2,AARS2,FARS2,MARS,VARS,AARS,TARS,YARS2,WARS,FARSA,EPRS,RARS,HARS2,YARS |
| 2.556e-09 | -19.78 | TGACAGNY_V$MEIS1_01 | MSigDB lists | TGACAGNY_V$MEIS1_01 | 790 | 159 | 17758 | 2279 |
TMEM109,BCOR,UBR5,GIPR,ABL2,SREBF2,IKZF5,METTL8,CHD2,PRADC1,HCFC2,YARS,ETV1,SRPK2,ZBTB17,DPF3,GPM6A,SESN2,TXLNG,BAZ2A,ZNF414,ATG12,PITPNB,KCNH2,SOX4,SGK2,DENND4A,DLST,ST3GAL5,C1orf122,EIF4ENIF1,SUFU,GATA6,DNAJC1,HIC2,GREB1L,RUNX1,SPOCK2,DMTF1,TNRC6A,USP15,SEPHS2,TNNC1,TTN,AK2,JUP,RHOBTB1,PAX2,C16orf52,HES6,BARX2,XPO7,DOPEY1,FAM192A,RSPRY1,HR,UBE3A,MCAM,SLC7A11,DHX37,MYC,COPS3,BANF1,SAMD11,GTF2H1,IGF2BP1,CNOT4,ATP6V0D1,SERBP1,MYB,MSI2,CAMKK2,OBSCN,WWC1,PRDM1,ONECUT2,TCF7L2,NCDN,EXOC6,IRS1,ASCC3,ITPRIPL1,SPAG9,PDLIM1,NME7,HIF1A,ZZEF1,RIOK3,TBPL1,ASH1L,ID1,MAP2K5,DLL4,DNM3,PCNT,TRERF1,PAFAH1B1,HFM1,RNF24,LPCAT3,TNKS1BP1,GBF1,NOP56,PHC2,VPS18,ANKRD13A,NRF1,MGLL,RAB7A,R3HDM1,GNL1,SLC35D1,FKBP3,TJAP1,WARS,BAZ1A,SIX5,HOXA3,TRAF3,RPS6KB1,NFRKB,ZBTB11,ATXN7L2,SSH2,BRAF,DNAJA4,MAP3K13,CLSTN2,SLC25A12,BHLHE40,FOXO3,MBNL1,FAM49A,NEDD4,STC2,ARHGAP1,LDLRAD3,ERRFI1,C15orf41,C12orf4,NAV3,TOP1,GPHN,IL11RA,AP4S1,MON1A,ZNF821,ZC3H18,SCFD2,ARHGEF12,R3HDM2,ANXA1,DDX50,USP20,MBD6,KIF1B,KDM4C,DDIT3,KAT6A |
| 2.609e-09 | -19.76 | tRNA aminoacylation for protein translation | biological process | GO:0006418 | 47 | 23 | 16441 | 2138 |
CARS,NARS2,SARS,WARS2,GARS,NARS,LARS2,HARS,RARS2,AARS2,FARS2,VARS,MARS,AARS,TARS,YARS2,WARS,FARSA,RARS,EPRS,HARS2,YARS,PPA1 |
| 2.681e-09 | -19.74 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6320 | 936 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,THOC5,ACTG1,CNTNAP3,AARS2,NAT10,SBF2,CSPP1,HLTF,SLC6A8,NUP160,PABPC4,AMBRA1,SKI,TOM1L1,PDZD2,MMP7,SREBF2,IKZF5,ZFHX3,RABGAP1L,MAD1L1,PDS5B,ZNF148,KDM5C,AVEN,SRRM2,FTSJ3,HMBOX1,NRAS,LIMA1,PTPRM,UPP1,GNL3,EHMT1,AP4B1,NFIA,KIF15,RFX2,MSRB3,C5AR1,PLEKHM3,C10orf76,RBM28,SLC9A5,ZNF197,SLC7A1,DDX3X,AHNAK,BRCA2,RAD18,BDH2,RUNX1,TPM1,ZNF532,HERC2,EP400,CLDN15,TRIP6,TRIO,NHS,PIK3R4,RSF1,CDC73,YARS2,ABCA7,SLC39A11,RSPRY1,DDX56,CNST,DHX37,CACNB2,MED24,PRMT5,MAP3K12,AGL,PABPC1,MYB,NOM1,HMGCR,KLRD1,GATAD2B,TIMM8B,BDNF,COL17A1,STAG1,ALG6,RB1CC1,PRDM16,ARID5B,EPS15L1,IDH3G,ZNF512B,IMPDH2,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,KPNA1,GTF2A1,CLASRP,TRAP1,SURF1,WDR33,MB21D2,ARHGAP10,SGSM3,SPRED2,SDSL,RAB11FIP4,ABCA3,ZNF516,TRERF1,DDX18,ATP6V1A,PAFAH1B1,BTBD2,ACTR3,DDR2,MYH9,ISG20L2,GRINA,ST3GAL6,EEA1,STAM,MCM9,PRKD3,CD96,ESAM,SPG21,ABCA12,ACD,TBC1D22A,ZKSCAN1,FMNL1,WAC,MMP14,ATRIP,NT5C,GSTA4,CEP63,MSH4,MTHFD2L,ZC3H3,DENND1A,LYST,PERP,KMT2D,KRT7,FAM111B,EIF3J,ARHGEF10,ATP6V0A1,CCNDBP1,MEF2D,NUDT15,DSP,FGFR1,TAF2,ARHGAP21,IQCH,KDM4B,NSMCE2,POLR3E,CAMKMT,WDR7,HOXA3,RPS6KB1,ZBTB11,LAMA5,YEATS2,CATSPERG,BAG1,MORC2,SHQ1,INSIG2,TRAK1,SF3A3,ATG2B,JMJD6,TGFB2,BHLHE40,MBNL1,POM121,KRI1,TADA3,SNW1,NPRL2,GATC,PVRL3,ACOT11,LTN1,SOX6,LYPLA2,SPTAN1,NUDC,DIS3L2,DDHD1,C21orf58,DDX24,ARHGAP39,ZC3H18,NXN,RSBN1,CCDC113,R3HDM2,ZNF467,PPIP5K2,PDE3B,ANXA1,RPA1,ETFDH,TRIB3,SRCAP,NSD1,BAZ2B,STX1A,ACOX1,GPAM,MTMR1,CORO2B,ANAPC4,KDM4C,CYP24A1,CUL7,WDR13,PPARGC1B,TFIP11,POLR1A,MFGE8,CSNK2A1,RNF43,TMEM132A,NLE1,GIT2,BIRC2,SCAF8,FRRS1,MAP2K3,ABL2,ECM1,ARHGAP18,COPS4,PHKA1,ANKRD11,TRIML2,UBAP2L,FAM184A,PTPRK,VPS13B,METTL1,FLNC,DSC3,DBN1,ZNF124,ATF4,ABCC4,MIOS,HARS,SKIV2L2,PPARG,KATNAL1,ANK2,CDK4,NOL6,GMFB,MARCKSL1,LAMA2,BRCA1,KCNH2,DLST,FLVCR1,ZNF91,CRYBG3,LSG1,PEX1,KIF16B,BSN,GLS,LSS,INSIG1,TP53BP1,ARL4A,E2F4,TECPR2,CCDC146,TNFRSF1A,SGSM2,ADAM9,MAGI1,USP15,CHMP4C,CTU2,XYLB,SARS,AOC3,FOXO1,STX8,MAPK8IP3,FAN1,BARX2,ZFP36L1,RLF,RNF40,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,CCDC167,CTR9,SYNJ2,PNPLA3,LRSAM1,NIPSNAP1,TRAPPC9,CAMKK2,LAMC1,CRADD,USP49,SETD2,HAUS6,RNH1,ZNFX1,METTL22,TRAPPC6B,TCF7L2,NAP1L5,ATXN7,SPAG9,DNAH17,SIL1,CASS4,SH3PXD2A,PRKAR2A,TESC,KCTD7,ID1,OLFM2,PAPD4,ARID2,LPCAT2,SLC2A1,RSL1D1,RIPK1,ZNF83,LPCAT3,RADIL,PPP1R9A,PAG1,PLXNB1,CAD,METTL16,ZNF608,IDI1,JAG1,NUP133,UBR1,ARMC5,FGGY,FSIP2,ZDHHC6,CYB5D1,HIRIP3,CCDC40,MYH15,ANO8,BCAP29,AKNAD1,AHCYL1,PRMT3,IPO11,CTC1,TMEM200A,KDM3B,SEC24A,WDR36,EVL,SSFA2,TEX19,KIRREL2,GLTSCR2,AKAP13,NUP214,USP36,TJAP1,IFT81,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,ATG7,ZNF436,INTS9,NFASC,PUS1,FAHD1,ZNF589,PPIL3,PARD3,UNC13D,MAP3K13,RFX1,FAM46B,C14orf159,ARFIP2,RBM19,FOXP1,RMI1,C15orf57,POGZ,BZW2,IQGAP2,FAM50A,NDUFV1,SACS,ZNF561,CWC27,CD44,FBXO31,C12orf4,AP4S1,ADAMTSL3,MON1A,SMARCAD1,ZMYM5,ABCF2,PLAC8L1,TEX14,TOP3A,DHX34,ARHGEF12,C11orf49,RANGAP1,YIPF3,PALLD,EXOG,TMEM175,SMPDL3B,MKX,POLR3G,CDH24,CACNB1,SAMD5,SRBD1,ZBTB8OS,ADAT2,TBX3,SET,MSH3,EIF2S1,FNTB,DNAJC12,RBM26,ZNF32,ITGB4,NR2F2,XPO6,KIF1B,MYCBP2,CGN,CUL4A,PRKCSH,PRKAB2,PLRG1,ADAMTS6,UBR5,AARS,LPIN1,GIPR,RNF111,SUCLG2,CHD2,CEP135,FUT11,SPAG6,ZNF646,DDN,GDAP1,OSBP2,NR6A1,ATG9A,ALDH1L2,EYA3,CUX1,SEMA3F,SON,FOXRED1,DDX60,PLCXD2,GZF1,DOT1L,OSBPL1A,SPOP,SH3GL1,SKIL,TRRAP,HSDL2,SH3RF1,CCNT1,ARL6IP5,HIC2,VPS13D,DNAH2,NRP1,WDR66,RFXAP,NMD3,SYNPO,SPOCK2,SPOCK3,PTPN14,PRPF38B,WDR75,IFT57,CDC42EP2,CELSR1,ANKRD17,ZHX3,LARS2,ST6GAL1,DLGAP4,TATDN3,OPHN1,GTF2IRD1,CCDC47,NDUFS7,ANXA10,FAM192A,TECTA,NAV1,HR,SLC7A11,NOVA2,SCAF1,USPL1,COPS3,PIGG,IGF2BP1,GTF3C3,CNOT4,SCAF11,SIK3,RREB1,PRIM2,SYNGAP1,AOC2,RDH10,TTYH2,PTPN12,ARID1A,PLCB1,EHBP1,MTR,ARIH2,PHF6,ATP9B,ZNF425,ASCC3,MTHFD2,KIDINS220,NSF,VCAN,SPEN,SRP68,ZZEF1,MED15,RIOK3,DPEP1,NCOR1,MACROD1,IQSEC2,HS2ST1,CPT1C,RTTN,PPDPF,PTCD2,SYT17,TRPM2,BIRC6,URB2,HFM1,UROD,KIAA0232,OLA1,TMEM104,AP1B1,CORO6,LTB4R,FLNB,IGSF1,PDE3A,NOP56,PHC2,TERF2IP,ASNS,TMEM184A,SLX4,SHC1,UCHL5,GLYR1,VGF,LPIN2,TTC3,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,CDK12,SAP30,ZCCHC14,GON4L,PREX1,KIAA1586,SATB2,MARCH6,PNN,MED16,GALK2,TBC1D16,STK10,ERC1,DHX57,BAZ1A,MSX2,YIPF2,SMARCC1,ZNF236,H2AFX,IFT140,TRMT2A,SLC4A7,TRAF3,KLHDC4,MDN1,ANXA2,TBXA2R,PDCD11,NOLC1,MID1,BRAF,UTP14A,TTC27,C10orf2,NFX1,SLC25A12,RTN4,DNAJC22,IKBKAP,GDPD5,INPP1,GIGYF2,REEP5,FAM8A1,PHLDA2,TMCO6,ABL1,ZNF483,NEBL,PMPCA,RDX,COPS7B,LARP4B,PLEKHG4,NAV3,FAM120B,TMC7,PFKFB4,SLC40A1,ZFYVE1,WDFY3,AGPAT4,KCNMA1,BMS1,KLF6,GUF1,RETSAT,FBXO21,ZNF155,IREB2,HELZ,ATM,MYOM2,DDIT3,SLC43A1,STK4,SLC37A3,MVK,PHF3,UBN1,NF1,RARS2,KIF5A,TRPM6,PLOD1,BCOR,SNAPC4,EDC3,SLC30A7,WNT2B,ZNF804A,DST,ANAPC1,LONRF2,ZNHIT6,MYH3,HYAL1,GPATCH1,B3GNTL1,POLR3B,SLC27A5,HCFC2,CCDC121,TRIM14,PRKACB,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,ZNF680,SLC38A1,SIRT6,ARRDC3,VWCE,GPCPD1,MINA,MTHFD1L,PITPNB,KMT2C,SOX4,ST3GAL5,YTHDF2,UBTF,TMEM132B,PAF1,EIF4ENIF1,SUFU,GATA6,CC2D1B,FAM114A2,CTAGE5,CSMD3,ABCC3,EME1,CLU,DMTF1,MTCH1,TNRC6A,SLC12A7,DCTN3,RELL2,CHST11,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,SMG7,EVPL,QSER1,PHGDH,ETFB,DDIT4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,ZCCHC7,PRF1,NRIP1,LRP3,POLR1E,AKAP11,HSD17B14,MTHFD1,KRT20,PDE4A,TSTA3,PPAT,TRA2A,ELOVL6,JMJD1C,PRDM1,CORIN,SYT1,AGAP1,HERPUD1,POP1,MGAT2,APBB3,SYCP2L,UBAP2,ATAD5,MYBBP1A,KIAA0355,FSCN1,INTS5,FDPS,SDCCAG8,RRAGA,EXOC4,HK2,PTRH2,SLC16A1,TBCK,C7orf26,N4BP2L2,DMXL2,TCF12,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,TMEM183A,SMARCA4,COBLL1,TMEM177,ST7L,ARSJ,PIBF1,UBTD2,GBF1,DHX35,ZSCAN5A,RIOK2,ZC3H13,VPS18,FARSA,MPHOSPH10,CAMTA2,SOCS1,NVL,RPS6KL1,PPFIBP1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,HTRA2,AUP1,MOSPD1,HN1,ACSL5,NARS2,PHLDB2,COL5A2,SFSWAP,PARP2,NLN,ATXN1,DKC1,ATP8B2,EDEM2,UBR4,C1orf174,PUSL1,RAB10,WARS,RAD54B,PLIN2,ARMC4,COPS5,ARNTL,SLC25A11,FKBP5,DISP1,TMEM101,ARC,NFRKB,HEATR1,USP11,ECHDC1,TSPAN5,YDJC,BCKDK,SH2D3A,C17orf80,SUPT6H,CAMK1,DYM,KLC4,PDE4B,CLSTN2,LETMD1,ATF7IP,CCDC7,BMP6,MFSD10,SFI1,HDDC2,PRKCH,PEX7,GART,HAS3,SEC24C,DSG2,TANK,KDELC1,TTC17,FBL,DMRT1,RPS6KB2,TOP1,KDM6B,SLC6A16,DNMBP,ZNF821,CRIM1,KDM5A,TEAD1,ANKMY2,PPP1R21,ZNF324B,MARS,PHACTR2,PDE2A,NAPEPLD,SYMPK,RERE,ZNF708,DAGLB,WDR35,ZNF330,MBD6,POLR1C,MMP16,NIT1 |
| 2.696e-09 | -19.73 | biliary_tract | COSMIC cancer mutations | biliary_tract | 16126 | 2139 | 17775 | 2278 |
CDCP1,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,MSRB3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,CAD,DUS4L,UBR1,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,INTS12,C16orf58,MSH4,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,C16orf52,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 2.818e-09 | -19.69 | large_intestine-colon-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma-adenocarcinoma | 17299 | 2255 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,METTL23,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,TMEM241,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 2.884e-09 | -19.66 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6322 | 936 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,THOC5,ACTG1,CNTNAP3,AARS2,NAT10,SBF2,CSPP1,HLTF,SLC6A8,NUP160,PABPC4,AMBRA1,SKI,TOM1L1,PDZD2,MMP7,SREBF2,IKZF5,ZFHX3,RABGAP1L,MAD1L1,PDS5B,ZNF148,KDM5C,AVEN,SRRM2,FTSJ3,HMBOX1,NRAS,LIMA1,PTPRM,UPP1,GNL3,EHMT1,AP4B1,NFIA,KIF15,RFX2,MSRB3,C5AR1,PLEKHM3,C10orf76,RBM28,SLC9A5,ZNF197,SLC7A1,DDX3X,AHNAK,BRCA2,RAD18,BDH2,RUNX1,TPM1,ZNF532,HERC2,EP400,CLDN15,TRIP6,TRIO,NHS,PIK3R4,RSF1,CDC73,YARS2,ABCA7,SLC39A11,RSPRY1,DDX56,CNST,DHX37,CACNB2,MED24,PRMT5,MAP3K12,AGL,PABPC1,MYB,NOM1,HMGCR,KLRD1,GATAD2B,TIMM8B,BDNF,COL17A1,STAG1,ALG6,RB1CC1,PRDM16,ARID5B,EPS15L1,IDH3G,ZNF512B,IMPDH2,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,KPNA1,GTF2A1,CLASRP,TRAP1,SURF1,WDR33,MB21D2,ARHGAP10,SGSM3,SPRED2,SDSL,RAB11FIP4,ABCA3,ZNF516,TRERF1,DDX18,ATP6V1A,PAFAH1B1,BTBD2,ACTR3,DDR2,MYH9,ISG20L2,GRINA,ST3GAL6,EEA1,STAM,MCM9,PRKD3,CD96,ESAM,SPG21,ABCA12,ACD,TBC1D22A,ZKSCAN1,FMNL1,WAC,MMP14,ATRIP,NT5C,GSTA4,CEP63,MSH4,MTHFD2L,ZC3H3,DENND1A,LYST,PERP,KMT2D,KRT7,FAM111B,EIF3J,ARHGEF10,ATP6V0A1,CCNDBP1,MEF2D,NUDT15,DSP,FGFR1,TAF2,ARHGAP21,IQCH,KDM4B,NSMCE2,POLR3E,CAMKMT,WDR7,HOXA3,RPS6KB1,ZBTB11,LAMA5,YEATS2,CATSPERG,BAG1,MORC2,SHQ1,INSIG2,TRAK1,SF3A3,ATG2B,JMJD6,TGFB2,BHLHE40,MBNL1,POM121,KRI1,TADA3,SNW1,NPRL2,GATC,PVRL3,ACOT11,LTN1,SOX6,LYPLA2,SPTAN1,NUDC,DIS3L2,DDHD1,C21orf58,DDX24,ARHGAP39,ZC3H18,NXN,RSBN1,CCDC113,R3HDM2,ZNF467,PPIP5K2,PDE3B,ANXA1,RPA1,ETFDH,TRIB3,SRCAP,NSD1,BAZ2B,STX1A,ACOX1,GPAM,MTMR1,CORO2B,ANAPC4,KDM4C,CYP24A1,CUL7,WDR13,PPARGC1B,TFIP11,POLR1A,MFGE8,CSNK2A1,RNF43,TMEM132A,NLE1,GIT2,BIRC2,SCAF8,FRRS1,MAP2K3,ABL2,ECM1,ARHGAP18,COPS4,PHKA1,ANKRD11,TRIML2,UBAP2L,FAM184A,PTPRK,VPS13B,METTL1,FLNC,DSC3,DBN1,ZNF124,ATF4,ABCC4,MIOS,HARS,SKIV2L2,PPARG,KATNAL1,ANK2,CDK4,NOL6,GMFB,MARCKSL1,LAMA2,BRCA1,KCNH2,DLST,FLVCR1,ZNF91,CRYBG3,LSG1,PEX1,KIF16B,BSN,GLS,LSS,INSIG1,TP53BP1,ARL4A,E2F4,TECPR2,CCDC146,TNFRSF1A,SGSM2,ADAM9,MAGI1,USP15,CHMP4C,CTU2,XYLB,SARS,AOC3,FOXO1,STX8,MAPK8IP3,FAN1,BARX2,ZFP36L1,RLF,RNF40,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,CCDC167,CTR9,SYNJ2,PNPLA3,LRSAM1,NIPSNAP1,TRAPPC9,CAMKK2,LAMC1,CRADD,USP49,SETD2,HAUS6,RNH1,ZNFX1,METTL22,TRAPPC6B,TCF7L2,NAP1L5,ATXN7,SPAG9,DNAH17,SIL1,CASS4,SH3PXD2A,PRKAR2A,TESC,KCTD7,ID1,OLFM2,PAPD4,ARID2,LPCAT2,SLC2A1,RSL1D1,RIPK1,ZNF83,LPCAT3,RADIL,PPP1R9A,PAG1,PLXNB1,CAD,METTL16,ZNF608,IDI1,JAG1,NUP133,UBR1,ARMC5,FGGY,FSIP2,ZDHHC6,CYB5D1,HIRIP3,CCDC40,MYH15,ANO8,BCAP29,AKNAD1,AHCYL1,PRMT3,IPO11,CTC1,TMEM200A,KDM3B,SEC24A,WDR36,EVL,SSFA2,TEX19,KIRREL2,GLTSCR2,AKAP13,NUP214,USP36,TJAP1,IFT81,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,ATG7,ZNF436,INTS9,NFASC,PUS1,FAHD1,ZNF589,PPIL3,PARD3,UNC13D,MAP3K13,RFX1,FAM46B,C14orf159,ARFIP2,RBM19,FOXP1,RMI1,C15orf57,POGZ,BZW2,IQGAP2,FAM50A,NDUFV1,SACS,ZNF561,CWC27,CD44,FBXO31,C12orf4,AP4S1,ADAMTSL3,MON1A,SMARCAD1,ZMYM5,ABCF2,PLAC8L1,TEX14,TOP3A,DHX34,ARHGEF12,C11orf49,RANGAP1,YIPF3,PALLD,EXOG,TMEM175,SMPDL3B,MKX,POLR3G,CDH24,CACNB1,SAMD5,SRBD1,ZBTB8OS,ADAT2,TBX3,SET,MSH3,EIF2S1,FNTB,DNAJC12,RBM26,ZNF32,ITGB4,NR2F2,XPO6,KIF1B,MYCBP2,CGN,CUL4A,PRKCSH,PRKAB2,PLRG1,ADAMTS6,UBR5,AARS,LPIN1,GIPR,RNF111,SUCLG2,CHD2,CEP135,FUT11,SPAG6,ZNF646,DDN,GDAP1,OSBP2,NR6A1,ATG9A,ALDH1L2,EYA3,CUX1,SEMA3F,SON,FOXRED1,DDX60,PLCXD2,GZF1,DOT1L,OSBPL1A,SPOP,SH3GL1,SKIL,TRRAP,HSDL2,SH3RF1,CCNT1,ARL6IP5,HIC2,VPS13D,DNAH2,NRP1,WDR66,RFXAP,NMD3,SYNPO,SPOCK2,SPOCK3,PTPN14,PRPF38B,WDR75,IFT57,CDC42EP2,CELSR1,ANKRD17,ZHX3,LARS2,ST6GAL1,DLGAP4,TATDN3,OPHN1,GTF2IRD1,CCDC47,NDUFS7,ANXA10,FAM192A,TECTA,NAV1,HR,SLC7A11,NOVA2,SCAF1,USPL1,COPS3,PIGG,IGF2BP1,GTF3C3,CNOT4,SCAF11,SIK3,RREB1,PRIM2,SYNGAP1,AOC2,RDH10,TTYH2,PTPN12,ARID1A,PLCB1,EHBP1,MTR,ARIH2,PHF6,ATP9B,ZNF425,ASCC3,MTHFD2,KIDINS220,NSF,VCAN,SPEN,SRP68,ZZEF1,MED15,RIOK3,DPEP1,NCOR1,MACROD1,IQSEC2,HS2ST1,CPT1C,RTTN,PPDPF,PTCD2,SYT17,TRPM2,BIRC6,URB2,HFM1,UROD,KIAA0232,OLA1,TMEM104,AP1B1,CORO6,LTB4R,FLNB,IGSF1,PDE3A,NOP56,PHC2,TERF2IP,ASNS,TMEM184A,SLX4,SHC1,UCHL5,GLYR1,VGF,LPIN2,TTC3,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,CDK12,SAP30,ZCCHC14,GON4L,PREX1,KIAA1586,SATB2,MARCH6,PNN,MED16,GALK2,TBC1D16,STK10,ERC1,DHX57,BAZ1A,MSX2,YIPF2,SMARCC1,ZNF236,H2AFX,IFT140,TRMT2A,SLC4A7,TRAF3,KLHDC4,MDN1,ANXA2,TBXA2R,PDCD11,NOLC1,MID1,BRAF,UTP14A,TTC27,C10orf2,NFX1,SLC25A12,RTN4,DNAJC22,IKBKAP,GDPD5,INPP1,GIGYF2,REEP5,FAM8A1,PHLDA2,TMCO6,ABL1,ZNF483,NEBL,PMPCA,RDX,COPS7B,LARP4B,PLEKHG4,NAV3,FAM120B,TMC7,PFKFB4,SLC40A1,ZFYVE1,WDFY3,AGPAT4,KCNMA1,BMS1,KLF6,GUF1,RETSAT,FBXO21,ZNF155,IREB2,HELZ,ATM,MYOM2,DDIT3,SLC43A1,STK4,SLC37A3,MVK,PHF3,UBN1,NF1,RARS2,KIF5A,TRPM6,PLOD1,BCOR,SNAPC4,EDC3,SLC30A7,WNT2B,ZNF804A,DST,ANAPC1,LONRF2,ZNHIT6,MYH3,HYAL1,GPATCH1,B3GNTL1,POLR3B,SLC27A5,HCFC2,CCDC121,TRIM14,PRKACB,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,ZNF680,SLC38A1,SIRT6,ARRDC3,VWCE,GPCPD1,MINA,MTHFD1L,PITPNB,KMT2C,SOX4,ST3GAL5,YTHDF2,UBTF,TMEM132B,PAF1,EIF4ENIF1,SUFU,GATA6,CC2D1B,FAM114A2,CTAGE5,CSMD3,ABCC3,EME1,CLU,DMTF1,MTCH1,TNRC6A,SLC12A7,DCTN3,RELL2,CHST11,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,SMG7,EVPL,QSER1,PHGDH,ETFB,DDIT4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,ZCCHC7,PRF1,NRIP1,LRP3,POLR1E,AKAP11,HSD17B14,MTHFD1,KRT20,PDE4A,TSTA3,PPAT,TRA2A,ELOVL6,JMJD1C,PRDM1,CORIN,SYT1,AGAP1,HERPUD1,POP1,MGAT2,APBB3,SYCP2L,UBAP2,ATAD5,MYBBP1A,KIAA0355,FSCN1,INTS5,FDPS,SDCCAG8,RRAGA,EXOC4,HK2,PTRH2,SLC16A1,TBCK,C7orf26,N4BP2L2,DMXL2,TCF12,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,TMEM183A,SMARCA4,COBLL1,TMEM177,ST7L,ARSJ,PIBF1,UBTD2,GBF1,DHX35,ZSCAN5A,RIOK2,ZC3H13,VPS18,FARSA,MPHOSPH10,CAMTA2,SOCS1,NVL,RPS6KL1,PPFIBP1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,HTRA2,AUP1,MOSPD1,HN1,ACSL5,NARS2,PHLDB2,COL5A2,SFSWAP,PARP2,NLN,ATXN1,DKC1,ATP8B2,EDEM2,UBR4,C1orf174,PUSL1,RAB10,WARS,RAD54B,PLIN2,ARMC4,COPS5,ARNTL,SLC25A11,FKBP5,DISP1,TMEM101,ARC,NFRKB,HEATR1,USP11,ECHDC1,TSPAN5,YDJC,BCKDK,SH2D3A,C17orf80,SUPT6H,CAMK1,DYM,KLC4,PDE4B,CLSTN2,LETMD1,ATF7IP,CCDC7,BMP6,MFSD10,SFI1,HDDC2,PRKCH,PEX7,GART,HAS3,SEC24C,DSG2,TANK,KDELC1,TTC17,FBL,DMRT1,RPS6KB2,TOP1,KDM6B,SLC6A16,DNMBP,ZNF821,CRIM1,KDM5A,TEAD1,ANKMY2,PPP1R21,ZNF324B,MARS,PHACTR2,PDE2A,NAPEPLD,SYMPK,RERE,ZNF708,DAGLB,WDR35,ZNF330,MBD6,POLR1C,MMP16,NIT1 |
| 2.967e-09 | -19.64 | transcription, DNA-templated | biological process | GO:0006351 | 2560 | 427 | 16441 | 2138 |
ZNF292,MYCBP2,ASCC1,PRKAB2,HLTF,CCNL2,ZNF44,GABPB2,LPIN1,MGA,SKI,ZNF37A,SREBF2,IKZF5,ZFHX3,RNF111,ZNF148,CHD2,KDM5C,MEIS3,ZNRD1,ZNF646,DPF3,HMBOX1,SETD1B,RNMT,NR6A1,EYA3,NFIA,TCEB3,CUX1,RFX2,C5AR1,DENND4A,SAP30BP,ZNF197,GZF1,DDX3X,SKIL,ZNF266,TRRAP,SUPT4H1,CCNT1,ZNF81,HIC2,RUNX1,BMI1,ZNF532,PTPN14,MEF2C,BANP,IFT57,EGR1,TRIP6,ZHX3,KHDRBS1,SIRT7,GTF2IRD1,RSF1,CDC73,CHD5,HR,ZNF586,SCAF1,MYC,ZNF326,MED24,GTF3C3,PRMT5,ZNF518B,MYB,GATAD2B,ZNF675,GTF2H3,WDR61,STAG1,RREB1,ZNF587,RB1CC1,PRDM16,ARID5B,ZNF512B,SMARCD3,ARID1A,NELFA,TRIM37,ONECUT2,SRA1,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,ASCC3,GTF2A1,HIF1A,CDK9,SPEN,MED15,ZBTB12,CCDC85B,ZNF160,PURB,CNOT6,NCOR1,ZFHX2,ZNF254,ZNF516,TRERF1,GTF2H2C,NPAS2,ZBTB37,FOSL2,SAFB2,RING1,TERF2IP,CHD7,ZNF827,KDM2A,ZKSCAN1,UCHL5,WAC,LPIN2,KMT2A,LSM10,CASP8AP2,SAP30,BRD4,KMT2D,ZNF480,NPM3,ATF7IP2,SATB2,MED16,MEF2D,PNN,SETD7,FGFR1,ZBTB25,VDR,TAF2,BAZ1A,DNTTIP1,MSX2,SMARCC1,KDM4B,ELP2,HIPK2,G6PD,ZNF236,MBTD1,POLR3E,HOXA3,ZBTB11,TROVE2,COMMD10,HMGA2,NCOR2,ZNF786,C10orf2,TCF3,ZNF280C,NFX1,ID2,JMJD6,MYNN,TRIM22,BHLHE40,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF483,TADA3,ZNF239,SNW1,POLR3D,COMMD9,PTRF,SUV39H2,ELP5,TAF3,YBX3,ZNF710,SOX6,FAM120B,TSHZ1,TTLL5,APEX1,ZNF467,KLF6,FOXC1,UBC,POLR2A,ZFP62,TRIB3,SRCAP,NSD1,BAZ2B,ZNF155,ARID3B,DDIT3,KDM4C,KAT6A,ZNF76,PHF3,GPBP1L1,ATRX,KMT2E,PPARGC1B,POLR1A,CSNK2A1,ZNF107,BCOR,SIRT2,SNAPC4,BIRC2,SMARCB1,SRSF2,PHF5A,YLPM1,JAZF1,HKR1,RELB,ZEB1,POLR3B,ZNF85,ZNF3,ETV1,ZMYM2,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,SESN2,ZNF124,TXLNG,ZNF195,PPARG,ZNF414,BAZ2A,ZNF680,MED27,MINA,HDAC8,BRCA1,SOX4,ZSCAN2,KMT2C,ZNF91,TAF9B,MLLT10,PAF1,GLS,UBTF,TCF7L1,GATA6,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,PQBP1,CRCP,DLX2,ZC3H8,ZNF397,BEND6,NOCT,DMTF1,EMSY,FOXO1,TAF1,PAX2,DPF2,SMAD7,LAMTOR3,HES6,MED13L,BARX2,ZIC2,RLF,ARID1B,DDIT4,ELL,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,PAXBP1,TLE3,JMJD1C,ELP3,SETD2,WBSCR22,ZFP14,WWC1,PRDM1,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,MYBBP1A,RRAGA,TBPL1,ZNF430,ZFP90,TBL1X,ZBTB24,NR2C2AP,TCF12,ID1,ASH1L,ARID2,SMARCA4,PBX1,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,ZSCAN5A,RRN3,NRF1,ZBTB21,CAMTA2,ZNF142,ZFP37,RNF2,FHIT,CPSF3,ZNF460,UTP4,MAML3,KDM3B,KAT8,PCGF3,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,ZNF251,BATF3,SMAD3,IKZF4,ADNP,SIX5,COPS5,ZNF557,KLF4,ZNF333,CEBPZ,ARNTL,ZNF436,SRFBP1,MED20,ZNF18,NFRKB,BRD9,ZNF507,DNAJC2,NIFK,SUPT6H,RFX1,AGO2,PPHLN1,MED18,ATF7IP,FOXP1,ZNF594,ZNF561,POLR1B,DMRT1,PKNOX1,SNAPC5,ARNTL2,TRNP1,MSX1,KDM5B,ZNF821,TEAD1,ZNF654,PSPC1,FOXN3,KDM5A,ZMYM5,SCMH1,ZNF324B,MEN1,ZNF407,POLR3A,RERE,ZNF221,POLR3G,ZNF708,L3MBTL3,TBX3,TAF4,CSRNP1,BCAS3,NCBP2,ZNF32,MYRF,RBPJ,TAF12,POLR1C,NFKBIB,NR2F2 |
| 3.087e-09 | -19.60 | colon | COSMIC cancer mutations | colon | 17300 | 2255 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,METTL23,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,TMEM241,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 3.125e-09 | -19.58 | nucleic acid-templated transcription | biological process | GO:0097659 | 2561 | 427 | 16441 | 2138 |
ZNF292,MYCBP2,ASCC1,PRKAB2,HLTF,CCNL2,ZNF44,GABPB2,LPIN1,MGA,SKI,ZNF37A,SREBF2,IKZF5,ZFHX3,RNF111,ZNF148,CHD2,KDM5C,MEIS3,ZNRD1,ZNF646,DPF3,HMBOX1,SETD1B,RNMT,NR6A1,EYA3,NFIA,TCEB3,CUX1,RFX2,C5AR1,DENND4A,SAP30BP,ZNF197,GZF1,DDX3X,SKIL,ZNF266,TRRAP,SUPT4H1,CCNT1,ZNF81,HIC2,RUNX1,BMI1,ZNF532,PTPN14,MEF2C,BANP,IFT57,EGR1,TRIP6,ZHX3,KHDRBS1,SIRT7,GTF2IRD1,RSF1,CDC73,CHD5,HR,ZNF586,SCAF1,MYC,ZNF326,MED24,GTF3C3,PRMT5,ZNF518B,MYB,GATAD2B,ZNF675,GTF2H3,WDR61,STAG1,RREB1,ZNF587,RB1CC1,PRDM16,ARID5B,ZNF512B,SMARCD3,ARID1A,NELFA,TRIM37,ONECUT2,SRA1,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,ASCC3,GTF2A1,HIF1A,CDK9,SPEN,MED15,ZBTB12,CCDC85B,ZNF160,PURB,CNOT6,NCOR1,ZFHX2,ZNF254,ZNF516,TRERF1,GTF2H2C,NPAS2,ZBTB37,FOSL2,SAFB2,RING1,TERF2IP,CHD7,ZNF827,KDM2A,ZKSCAN1,UCHL5,WAC,LPIN2,KMT2A,LSM10,CASP8AP2,SAP30,BRD4,KMT2D,ZNF480,NPM3,ATF7IP2,SATB2,MED16,MEF2D,PNN,SETD7,FGFR1,ZBTB25,VDR,TAF2,BAZ1A,MSX2,DNTTIP1,SMARCC1,KDM4B,ELP2,HIPK2,G6PD,ZNF236,MBTD1,POLR3E,HOXA3,ZBTB11,TROVE2,COMMD10,HMGA2,NCOR2,ZNF786,C10orf2,TCF3,ZNF280C,NFX1,ID2,JMJD6,MYNN,TRIM22,BHLHE40,IKBKAP,FOXO3,MAD2L2,SFR1,ZNF483,TADA3,ZNF239,SNW1,POLR3D,COMMD9,PTRF,SUV39H2,ELP5,TAF3,YBX3,ZNF710,SOX6,FAM120B,TSHZ1,TTLL5,APEX1,ZNF467,KLF6,FOXC1,UBC,POLR2A,ZFP62,TRIB3,SRCAP,NSD1,BAZ2B,ZNF155,ARID3B,DDIT3,KDM4C,KAT6A,ZNF76,PHF3,GPBP1L1,ATRX,KMT2E,PPARGC1B,POLR1A,CSNK2A1,ZNF107,BCOR,SIRT2,SNAPC4,BIRC2,SMARCB1,SRSF2,PHF5A,YLPM1,JAZF1,HKR1,RELB,ZEB1,POLR3B,ZNF85,ZNF3,ETV1,ZMYM2,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,SESN2,ZNF124,TXLNG,ZNF195,PPARG,ZNF414,BAZ2A,ZNF680,MED27,MINA,HDAC8,BRCA1,SOX4,ZSCAN2,KMT2C,ZNF91,TAF9B,MLLT10,PAF1,GLS,UBTF,TCF7L1,GATA6,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,PQBP1,CRCP,DLX2,ZC3H8,ZNF397,BEND6,NOCT,DMTF1,EMSY,FOXO1,TAF1,PAX2,DPF2,SMAD7,LAMTOR3,HES6,MED13L,BARX2,ZIC2,RLF,ARID1B,DDIT4,ELL,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,PAXBP1,TLE3,ELP3,JMJD1C,SETD2,WBSCR22,ZFP14,WWC1,PRDM1,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,MYBBP1A,RRAGA,TBPL1,ZNF430,ZFP90,TBL1X,ZBTB24,NR2C2AP,TCF12,ID1,ASH1L,ARID2,SMARCA4,PBX1,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,ZSCAN5A,RRN3,NRF1,ZBTB21,CAMTA2,ZNF142,ZFP37,RNF2,FHIT,CPSF3,ZNF460,UTP4,MAML3,KDM3B,KAT8,PCGF3,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,ZNF251,BATF3,SMAD3,IKZF4,ADNP,SIX5,COPS5,ZNF557,KLF4,ZNF333,CEBPZ,ARNTL,ZNF436,SRFBP1,MED20,ZNF18,NFRKB,BRD9,ZNF507,DNAJC2,NIFK,SUPT6H,RFX1,AGO2,PPHLN1,MED18,ATF7IP,FOXP1,ZNF594,ZNF561,POLR1B,DMRT1,PKNOX1,SNAPC5,ARNTL2,TRNP1,MSX1,KDM5B,ZNF821,TEAD1,ZNF654,PSPC1,FOXN3,KDM5A,ZMYM5,SCMH1,ZNF324B,MEN1,ZNF407,POLR3A,RERE,ZNF221,POLR3G,ZNF708,L3MBTL3,TBX3,TAF4,CSRNP1,BCAS3,NCBP2,ZNF32,MYRF,RBPJ,TAF12,POLR1C,NFKBIB,NR2F2 |
| 3.127e-09 | -19.58 | cellular component organization | biological process | GO:0016043 | 5336 | 813 | 16441 | 2138 |
ARHGAP26,ACTG1,AARS2,MRPL10,MKS1,CACNA1H,TUBE1,SBF2,HLTF,COA1,NUP160,SYNJ1,LPAR3,CIAPIN1,AMBRA1,SKI,MMP7,NEK6,PMAIP1,AP1M1,MAD1L1,PDS5B,WIZ,KDM5C,FXN,NRAS,LIMA1,PTPRM,EHMT1,AP4B1,NFIA,KIF15,WDHD1,MCL1,MCM2,TMSB4X,STOML2,DDX3X,AHNAK,RBSN,BRCA2,SUPT4H1,MPV17,FIS1,TPM1,MEF2C,BANP,EP400,CLDN15,TRIP6,TRIO,SIRT7,PIK3R4,RSF1,CLINT1,CDC73,SLC1A1,YARS2,ABCA7,CHN1,MCM5,CACNB2,WDR60,MED24,ANP32B,GEMIN4,MRPL21,CCDC88C,PRMT5,MAP3K12,TOMM34,FMNL2,MYB,HMGCR,PEA15,GATAD2B,TIMM8B,BDNF,IFRD1,COL17A1,WDR61,STAG1,KCNQ3,MYO10,TSPYL4,RB1CC1,PRDM16,ARID5B,ATAT1,SMARCD3,MAP7D1,SNAP25,IMPDH2,CPT1A,TRIM37,ONECUT2,NCDN,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,FGFBP1,LEMD3,SURF1,KIAA0196,ARHGAP10,SRP14,DNM3,PAFAH1B1,ATP6V1A,ACTR3,VTI1A,DDR2,MYH9,NUP43,STAM,EEA1,RPGRIP1L,ABCA12,ACD,FMNL1,WAC,CLCN6,MMP14,CEP63,MSH4,PERP,LYST,KMT2D,EIF3J,ASUN,ARHGEF10,ATP6V0A1,DSP,TTC28,FGFR1,PES1,TAF2,HLA-DMA,ARHGAP21,CDC16,KDM4B,ELP2,MISP,NSMCE2,HIPK2,ARL13B,BRCC3,YEATS2,LAMA5,RAB30,MAPT,HMGA2,SHQ1,XPC,SF3A3,JMJD6,ATG2B,GAS6,AKT1S1,TRIM22,TGFB2,PSMF1,MBNL1,POM121,TADA3,PSMG4,GATC,SUV39H2,TMSB10,PVRL3,UNC13A,ANXA5,ACTR3B,SOX6,DIS3L2,SPTAN1,NUDC,DDHD1,FGF9,CEP83,VPS37A,ZC4H2,ARHGAP39,MRPS10,CCDC113,UBE2K,FOXC1,UBC,ANXA1,MRPL36,RPA1,NSD1,SRCAP,PXDN,POLE2,HERC1,ACOX1,BMP4,UQCC1,ANAPC4,CORO2B,KDM4C,CUL7,TRIM16,PPARGC1B,TFIP11,MFGE8,NREP,CSNK2A1,SEC16A,COX10,BIRC2,ABL2,COPS4,ARHGAP18,MARVELD2,NCKIPSD,XRCC2,RAN,POLE3,ETV1,SF3A1,PTPRK,CDC37,FLNC,DBN1,CHD9,FMNL3,AEBP2,HARS,BAZ2A,CDK4,ANK2,KATNAL1,COL4A3BP,PSMG1,ATG12,LAMA2,BRCA1,MGST1,CXADR,CCDC28B,PEX1,BSN,GLS,HPRT1,TCF7L1,CHD3,PER1,E2F4,TNFRSF1A,RAD51B,AHNAK2,ADAM9,MAGI1,UQCC2,C2CD5,USP15,CHMP4C,TTN,MCM6,STX8,NKD2,MAPK8IP3,HSD17B10,LAMTOR3,SMAD7,ZIC2,RLF,DNAH1,ARID1B,SPIRE1,RNF40,ABCA5,CEP290,MBD2,VPS72,PPIL2,VAPB,CTR9,TIMELESS,WNT16,LRSAM1,TRAPPC9,LAMC1,IFT43,USP49,HAUS6,SETD2,BCS1L,OBSCN,TRAPPC6B,SUPT5H,TCF7L2,NAP1L5,ATXN7,SPAG9,PALB2,SNAP23,TBPL1,NAPA,BRSK2,TESC,USP7,KCTD7,SART1,CYLD,ARID2,LPCAT2,RBFOX2,RPS29,SLC2A1,GPR143,PPP2R2A,RIPK1,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,PLXNB1,KDM1A,DENR,NRF1,NUP133,GRIN2C,DNAJB6,IKBKB,ZDHHC6,HIRIP3,CCDC40,RNF2,ETF1,CORO1A,PRMT3,CTC1,PRPF19,SEC24A,KAT8,KDM3B,WDR36,EVL,TUBA1A,RAB7A,THSD4,C1QTNF1,VIM,TMEM123,NUP214,EIF3H,TJAP1,SMAD3,RANBP2,IFT81,RBBP8,TIMM17A,ITGA2,ATG7,NFASC,AP2S1,PARD3,NIFK,ESCO1,MINK1,KIZ,HM13,AGO2,ARFIP2,MAP1S,CSNK1A1,POGZ,HIST2H2AB,IQGAP2,ANXA7,PRICKLE2,HIST2H3D,POLR1B,CD44,HSD17B12,AP4S1,SMARCAD1,TEX14,TOP3A,FERMT2,ARHGEF12,HIST1H4J,PALLD,RHOT2,CHCHD6,ZRANB3,MKX,DKK1,CENPP,CDH24,CACNB1,TMEM237,L3MBTL3,SET,MSH3,BCAS3,EIF2S1,NDUFAF5,MYRF,RBPJ,TAF12,ITGB4,CGN,MYCBP2,CUL4A,PRKAB2,ENAH,PRKCA,RAC3,LPIN1,EXOC1,RPS16,S100A10,CHD2,ME1,CEP135,SEH1L,SPAG6,ACADS,DPF3,GDAP1,SETD1B,ATG9A,EYA3,SEMA3F,CAMSAP2,SUPT20H,HIST1H2BL,ZDHHC14,SON,FOXRED1,CLNS1A,DOT1L,SKIL,TRRAP,LSM14A,LUC7L3,SEMA3C,CCNB1IP1,NRP1,BMI1,SPOCK2,EFNB2,WDR75,IFT57,JUP,CDC42EP2,PRPF31,OPHN1,PID1,CCDC47,PRPF39,SSR4,CHD5,NDUFS7,FKBP1A,PRKCE,NAV1,HR,TSPAN2,USPL1,ASAP1,COPS3,MYC,MFAP2,CAV2,TERF2,SCAF11,USE1,DDX28,SYNGAP1,PRIM2,ANAPC13,POLA1,RAP1GAP2,KIAA0586,RAP1B,ARID1A,MTR,ANGPTL4,ATP9B,CAT,SEC31A,ASCC3,EPRS,KIDINS220,NSF,HIF1A,VCAN,SRP68,PEX13,NCOR1,IQSEC2,SMYD3,VMA21,RTTN,PTCD2,SYT17,BIRC6,HFM1,C1QTNF7,PLEK2,CORO6,AP1B1,RING1,FLNB,BLOC1S2,TERF2IP,NUBPL,CHD7,DECR1,SLX4,SHC1,KDM2A,PPID,DTNBP1,MRPS27,SSBP1,SERPINH1,KMT2A,SAP30,RFC4,CFAP221,MPP6,BRD4,RFC3,PDK1,MTIF2,WDPCP,PREX1,DLG4,LRRC8A,SATB2,SETD7,POLG2,SERP1,SNCA,VDR,BAZ1A,MSX2,CAMK2D,SMARCC1,DCXR,DNAJA3,MBTD1,H2AFX,IFT140,MDN1,ANXA2,NOLC1,SETD6,TROVE2,MID1,SSH2,NCOR2,BRAF,C10orf2,TCF3,KIF5C,RTN4,MLH1,CEP126,MON2,OPA1,NOL3,IKBKAP,GDPD5,RPS6KA5,MAD2L2,NEDD4,DCTPP1,ABL1,NEBL,ELP5,TRIAP1,NISCH,PMPCA,PHYKPL,HARS2,RDX,COPS7B,NLGN3,CELF1,DYNC2H1,PXN,TTLL5,APEX1,FZD3,KCNMA1,ADSL,BMS1,PACS1,PTK2,INF2,KLHL22,COL26A1,ZDHHC11,STX18,SVIL,ATM,NDUFS5,APAF1,BRWD3,RABEP1,IPO4,KAT6A,STK4,IMMP2L,LETM1,EIF3C,UBN1,ATRX,NF1,KMT2E,RARS2,PTPRA,KIF5A,FANCD2,TRPM6,PLOD1,BCOR,SIRT2,CUTC,EDC3,SMARCB1,MRPS30,DST,SRPRB,ANAPC1,RAP1A,CNIH3,KANSL1,ATG3,ZNHIT6,ANAPC11,ANAPC10,MYH3,LONP1,TRIP13,CARM1,TIMM50,SRPK2,LAMA4,GPM6A,SESN2,SKAP2,SIRT6,ITPA,TMEM216,HDAC8,CAV1,KMT2C,TCTN1,ARPC3,CHAF1A,TIMM44,GEMIN5,RHOU,UBTF,PAF1,HLCS,CTAGE5,PQBP1,BBIP1,CLU,COPS6,NOCT,MTCH1,EMSY,SLC12A7,DCTN3,FBXO45,FN1,TAF1,SEC24D,VTA1,PAX2,PHGDH,TIMM10,DDIT4,TOX4,CEP164,P3H1,ATXN2,BANF1,ISPD,SEMA3D,PRF1,ATP6V0D1,POLR1E,RANBP6,KRT20,PPAT,JMJD1C,ELP3,WBSCR22,LIG4,PSMA1,EIF2A,SYT1,BLOC1S4,C19orf70,UBE2E1,EXOC6,BICD1,FSCN1,FAT1,SDCCAG8,HK2,EXOC4,SLC16A1,TBL1X,FNBP1L,PDSS2,AGO3,CHMP2A,ASH1L,FEZ2,PCNT,CELSR3,PSTPIP2,MYO7A,TNXB,SMARCA4,TBCCD1,COBLL1,PIBF1,GBF1,SBDS,MIEF1,VPS18,RRN3,KCTD11,BRE,CBR4,ITGAX,MET,VCL,TMEM120B,TSPAN14,HTRA2,RTN4RL2,PHLDB2,COL5A2,PTBP2,MRRF,TOR1AIP2,ATP8B2,DKC1,RAB10,RAD54B,ARMC4,ALAD,KPNA3,ADNP,COPS5,SCARB1,ARC,BRD9,TSPAN5,TMEM33,DNAJC2,TNIK,SUPT6H,DYM,H2AFJ,ATF7IP,CHCHD10,SEMA3E,GFM2,SFI1,MRPS11,PEX7,SCN1B,HAS3,SEC24C,DSG2,SHMT2,TTC17,FBL,AMOT,DMRT1,MICAL3,TOP1,KDM6B,PPP1R9B,MSX1,GPHN,KDM5B,FGF2,KDM5A,SCMH1,PDE2A,MEN1,PEAK1,RERE,MFN2,GADD45A,WDR35,MPP7,AGTPBP1,VPS37B,NCBP2,ZAK,MMP16,ZSWIM6 |
| 3.128e-09 | -19.58 | mRNA processing | biological process | GO:0006397 | 414 | 97 | 16441 | 2138 |
SART1,PTCD2,THOC5,PAPD4,RBFOX2,TFIP11,PLRG1,PPIL1,PABPC1L,ZMAT2,DHX35,HNRNPA3,SCAF8,HNRNPLL,UBL5,SRSF2,BCAS2,PHF5A,NSRP1,GPATCH1,AHCYL1,CPSF3,SRRM2,ZC3H3,LSM10,CDK12,SRPK2,PRPF19,SF3A1,SNU13,PTBP2,DDX41,RNMT,SKIV2L2,SFSWAP,PNN,SON,RBM28,CLNS1A,PAF1,GEMIN5,SSU72,HNRNPR,LUC7L3,PQBP1,PRPF4,FUS,FIP1L1,TSEN2,PDCD11,NOCT,PPIL3,PRPF38B,SUPT6H,PRPF31,ZCCHC8,KHDRBS1,SF3A3,JMJD6,PRPF39,NOL3,PDCD7,RSRC1,CDC73,MBNL1,RBM20,SNW1,CTNNBL1,SCAF1,CWC27,ZNF326,BUD31,GTF2H1,CELF1,GEMIN4,PRMT5,PABPC1,HNRNPM,ADARB1,SCAF11,GTF2H3,USP49,TRA2A,PSPC1,SUPT5H,MBNL2,SYMPK,POLR2A,PRPF40B,SYNCRIP,CLASRP,HNRNPH3,SPEN,ZRANB2,NCBP2,RBM26,WDR33 |
| 3.899e-09 | -19.36 | PASINI_SUZ12_TARGETS_DN | MSigDB lists | PASINI_SUZ12_TARGETS_DN | 308 | 77 | 17758 | 2279 |
TCF12,CGN,AMOTL1,TUBB6,FOSL2,PHC2,JAG1,IDI1,S100A10,MARVELD2,SOCS6,MMP14,SERPINH1,VCL,CDK6,PERP,FLNC,DBN1,PHLDB2,TUBA1A,NR6A1,WLS,GMFB,LGALS1,TMEM123,VIM,CAV1,SOX4,SETD7,DSP,CXADR,PLIN2,SKIL,GNG2,BAZ1A,ZNF266,AHNAK,SEMA3C,ANXA2,TPM1,TROVE2,RBP1,LPP,HMGA2,FN1,KIF5C,ID2,SEMA3E,BHLHE40,TGFB2,FOXP1,CMTM3,PTRF,TSPAN2,MYC,KDELC1,ANXA5,ERRFI1,SAMD4A,CAV2,NT5E,PEA15,BDNF,RDH10,TPM4,PTPN12,PALLD,KLF6,UBE2E1,ANXA1,IRS1,PXDN,VCAN,BMP4,ADK,PDLIM5,CTXN1 |
| 3.936e-09 | -19.35 | NUCLEAR_LUMEN | MSigDB lists | NUCLEAR_LUMEN | 375 | 89 | 17758 | 2279 |
NPAS2,TFIP11,PPARGC1B,SMARCA4,SNAPC4,RPAIN,GIT2,NOP56,SMARCB1,RPP30,MPHOSPH10,SRSF2,NSRP1,JAZF1,INTS12,ZNF148,CPSF3,OGG1,TIMM50,SAP30,NR6A1,GNL3,NOL8,NOL6,WDHD1,ATXN1,HDAC8,MED16,DKC1,CHAF1A,GEMIN5,TAF2,UBTF,TRRAP,SMARCC1,ELP2,TP53BP1,CCNT1,HIPK2,ARNTL,INTS9,NOLC1,TAF1,PRPF31,HES6,MED18,RSF1,ZNF346,NOL3,IKBKAP,ARID1B,ABL1,SUB1,DDX56,INTS7,GTF2H1,GTF3C3,GEMIN4,PNMA1,POLR1E,CPSF3L,NOM1,TOP1,SCAF11,PPP1R9B,DDX24,POLA1,ELP3,SMARCD3,APTX,ARID1A,OASL,MEN1,SYMPK,NOP58,POLR2A,RPA1,POLR3G,POP1,MYBBP1A,HIF1A,ZNF330,INTS5,CDK9,SRP68,TAF4,TAF12,RBPJ,POLR1C |
| 3.967e-09 | -19.35 | MORF_ATRX | MSigDB lists | MORF_ATRX | 207 | 58 | 17758 | 2279 |
TCF12,ZNF292,EP400,SPRED2,INSIG2,ATRX,PAFAH1B1,SLC2A1,NFX1,KLHL18,TTI1,PARN,FAM8A1,PSMF1,MGA,ADH5,RAP1A,TBC1D22A,CACNB2,PPIL2,NCKIPSD,LTN1,SYNJ2,CEP135,MICAL3,RPS6KB2,KDM3B,KAT8,CHD9,SIK3,MSX1,TTLL5,POLA1,KIAA0586,BRCA1,MARCH6,EIF5B,ERC1,PIK3CB,RERE,HTR7,TAF2,SEC31A,SLC30A3,RBBP8,CHD3,MSH3,CTAGE5,FNTB,SLC25A11,ARHGAP12,ZNF32,NFRKB,RUNX1,IGBP1,MUTYH,SMG1,TMCC1 |
| 4.010e-09 | -19.33 | mRNA metabolic process | biological process | GO:0016071 | 591 | 127 | 16441 | 2138 |
SART1,PTCD2,THOC5,PAPD4,RBFOX2,DCP1B,TFIP11,PLRG1,RPS29,PPP2R2A,PPIL1,PABPC1L,TNKS1BP1,ZMAT2,DHX35,HNRNPA3,SCAF8,HNRNPLL,UBL5,EDC3,RPS16,SRSF2,BCAS2,PHF5A,NSRP1,ERI1,GPATCH1,ETF1,AHCYL1,CPSF3,SRRM2,ZC3H3,LSM10,CDK12,SRPK2,PRPF19,SF3A1,SNU13,PTBP2,DDX41,RNMT,SKIV2L2,SFSWAP,PNN,DKC1,SON,RBM28,CLNS1A,PAF1,GEMIN5,SSU72,HNRNPR,LUC7L3,PQBP1,PRPF4,FUS,FIP1L1,TSEN2,PDCD11,NOCT,PPIL3,SMG1,PRPF38B,ZCCHC8,PRPF31,SUPT6H,KHDRBS1,AGO2,SF3A3,SMG7,JMJD6,ZFP36L1,MLH1,PRPF39,NOL3,PDCD7,PARN,RSRC1,CDC73,MBNL1,RBM20,SNW1,CTNNBL1,CWC27,SCAF1,ZNF326,BUD31,GTF2H1,UPF2,CELF1,EXOSC4,GEMIN4,PRMT5,CNOT4,PABPC1,HNRNPM,DIS3L2,SCAF11,ADARB1,GTF2H3,EXOSC2,WDR61,USP49,TRA2A,PSPC1,EIF4A2,DHX34,RNH1,SUPT5H,MBNL2,SYMPK,POLR2A,CTIF,PRPF40B,SYNCRIP,RPL28,CLASRP,SPEN,HNRNPH3,ZCCHC6,ATM,NCBP2,ZRANB2,RBM26,CNOT6,WDR33,AGO3 |
| 4.039e-09 | -19.33 | liver-carcinoma | COSMIC cancer mutations | liver-carcinoma | 16152 | 2141 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,CAD,DUS4L,UBR1,ARMC5,FSIP2,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,ACP1,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,UBAP2,MYBBP1A,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,LYST,EIF3J,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,PSMG4,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,SEMA6A,FDX1,PLXNB1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,PACRGL,RFX2,AKAP12,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FAM71E1,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,MSX1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 4.455e-09 | -19.23 | transferase complex, transferring phosphorus-containing groups | cellular component | GO:0061695 | 241 | 64 | 17570 | 2233 |
BCCIP,PAPD4,PRKAB2,POLR1A,CCNL2,PHKA1,IKBKB,INTS12,POLR3B,POLE3,ZNRD1,CDK6,CDK12,PRKACB,BRD4,CDK4,ERC1,TAF9B,TAF2,PAF1,TRRAP,CCNT1,DNAJA3,POLR3E,INTS9,CRCP,MAP3K13,TAF1,PIK3R4,MED18,TGFBR2,CDC73,MAD2L2,TADA3,POLR3D,SNW1,TAF3,INTS7,CTR9,GTF2H1,POLR1B,PRPS1,POLR1E,CPSF3L,GTF2H3,WDR61,RB1CC1,POLA1,KDM5A,PIK3CB,POLR2A,VAC14,POLR3A,POLR3G,IRS1,POLE2,GTF2A1,INTS5,CDK9,TAF4,TBPL1,TAF12,POLR1C,PRKAR2A |
| 4.789e-09 | -19.16 | GARY_CD5_TARGETS_UP | MSigDB lists | GARY_CD5_TARGETS_UP | 457 | 103 | 17758 | 2279 |
ASCC1,NF1,PRKCSH,RBFOX2,CD99L2,TUBE1,GRINA,ABHD6,AARS,MAP2K3,LPIN1,ASNS,SREBF2,PMAIP1,THAP4,WAC,SLC38A2,ANKRD11,RELB,SUCLG2,TTC3,AHCYL1,ZMYM2,MPST,KAT8,SLC3A2,GARS,SESN2,ATF4,PDK1,GNG7,MARCH6,AKAP13,ATP5D,WARS,SPOP,ZFAND3,SLC7A1,LSS,CAMK2D,KDM4B,INSIG1,RLTPR,SCARB1,CCNB1IP1,CARS,KLHL24,BCKDK,SARS,MIF4GD,MINK1,BRAF,AUH,LRRC28,TAF1,SESTD1,CMTM8,TRIO,TRAK1,OPHN1,MAP1S,LETMD1,ZFP36L1,PHGDH,MFHAS1,RSRC1,DDIT4,GART,PI4KB,SLC7A11,ASAP1,LTN1,SHMT2,PCK2,LRSAM1,SLC25A1,HMGCR,FDFT1,KDM6B,MARCH9,PPP1R9B,IFRD1,PSAT1,FOXN3,TPM4,PACS1,MARS,R3HDM2,ARID1A,LENG8,TPRA1,TARS,ZRANB3,KPNA1,SET,SQLE,TBL1X,WDR33,MACROD1,DHCR7,LRRC41,STK4,SLC43A1 |
| 5.334e-09 | -19.05 | LIAO_METASTASIS | MSigDB lists | LIAO_METASTASIS | 499 | 110 | 17758 | 2279 |
ZNF292,BCAS4,LUZP1,NPAS2,URB2,SLC2A1,OLA1,ENAH,GYG1,SSBP2,NUP43,SLC6A8,SNAPC4,PPP1R9A,DENR,CHD7,ZNF827,ASNS,SHC1,PYCRL,UBAP2L,DTNBP1,CHD2,SERPINH1,YARS,ZC3H3,DENND1A,TRIP13,DBN1,DEAF1,PDK1,PTPRM,NLN,SEMA3F,MTHFD1L,KCNH2,SOX4,PUSL1,RAD54B,PES1,GLS,IKZF4,G6PD,HSPBAP1,ITGA2,HIC2,PAM,SEMA3C,ANXA2,NRP1,BRD9,LAMA5,ZNF532,PTPN14,PKIB,TMCC1,MORC2,DNAJA4,SULT1C2,RHOBTB1,PRPF31,SESTD1,TCF3,DLGAP4,IGF2BP2,ZIC2,TGFB2,NOL3,MBNL1,MFSD10,IGF2BP3,DDIT4,ZNF239,CEP164,FAM50A,MCAM,SLC7A11,SURF2,ASAP1,TAF3,ATIC,PPIL2,ALDH18A1,ZCCHC7,NAV3,PFKFB4,DDHD1,ARNTL2,ZNF234,IFRD1,TSTA3,USP42,PSMC3IP,ADSL,C11orf49,MARS,SNAP25,PLCB1,DKK1,VPS13C,TPD52L2,MTHFD2,UBAP2,TMEM237,SYNCRIP,VCAN,SLC25A19,PURB,NFKBIB,N4BP2L2 |
| 5.521e-09 | -19.01 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | 595 | 126 | 17758 | 2279 |
BCCIP,SLC2A1,DDR2,FANCD2,HLTF,IKBIP,STAM,PAG1,MPHOSPH10,ASNS,PMAIP1,UCHL5,ZEB1,SSBP1,RAN,SERPINH1,CPSF3,AVEN,LONP1,SEH1L,HN1,TMPO,SRPK2,RFC4,PMS1,GARS,SESN2,NRAS,SKIV2L2,MTIF2,NPM3,UPP1,TSN,GMFB,PSMG1,NLN,WDHD1,BRCA1,MTHFD1L,ENC1,MCM2,ARL5B,TMEM206,SNCA,GNAI1,SLC39A14,DDX3X,RBBP8,RAD18,TIMM17A,CEBPZ,SOCS4,BBIP1,ACP1,SLC4A7,ADAM9,HEATR1,NOLC1,XRCC4,AP2S1,NMD3,PTPN14,CARS,WDR75,DNAJC2,MCM6,DBF4,PHGDH,CSNK1A1,PDCD5,MBNL1,GFM2,PHLDA2,PIP4K2A,RSRC1,MAD2L2,SPIRE1,NEDD4,NAMPT,IGF2BP3,SUB1,EIF2S2,GART,SLC7A11,SUV39H2,INTS7,NOP16,ATIC,STC2,TANK,DYNC2H1,PSAT1,PPAT,ELOVL6,ABCF2,HAUS6,PSMC3IP,TPM4,UTP15,KIAA0586,PTPN12,FERMT2,ADSL,RAP1GDS1,BMS1,GPNMB,EIF5B,GUF1,EVI5,NOP58,TARS,KISS1R,ANXA1,RARS,EPRS,MTHFD2,PXDN,ZBTB8OS,ORC5,EIF2S1,SLC16A1,CDKAL1,NCBP2,MIPOL1,KIF1B,GALE |
| 6.436e-09 | -18.86 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 15558 | 2075 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,ST3GAL6,LCLAT1,MCM9,NDUFB3,CD96,SPG21,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,KIRREL2,RAB7A,ANKRD33B,EIF3H,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,APRT,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,ABL1,NEBL,S100A14,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RRN3,SOCS1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,PRKD3,ERI1,PYCRL,ATRIP,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,ACAP3,ARHGAP1,HNRNPM,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,DHX34,RAP1GDS1,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,SIGMAR1,AOC2,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,PIGN,CHST11,FN1,SEC24D,TAF1,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,TMEM63C,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,TRIM22,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RIPK1,SSBP2,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DDX60,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,HS2ST1,CPT1C,SYT17,UROD,CORO6,PTPRG,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,SATB2,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,CHMP2A,FEZ2,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,SPATS2,DHX35,ZC3H13,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CMTM8,VPS45,PDE4B,IGF2BP2,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,NIT1,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PCDH7,NEK6,PMAIP1,NSRP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,PACRGL,AKAP12,MCL1,SLC50A1,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,PRDM16,STPG1,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,PPP2R2A,ZNF83,KDM1A,DENR,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,C14orf159,MAP1S,ZNF346,CSNK1A1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,GNG7,EYA3,NOL8,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,TXN2,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,PTPN12,TTYH2,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,TNRC6A,SLC12A7,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,DSG2,SHMT2,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 7.010e-09 | -18.78 | cellular response to DNA damage stimulus | biological process | GO:0006974 | 736 | 150 | 16441 | 2138 |
IMMP2L,POLB,ASCC1,CUL4A,ATRX,TMEM109,FANCD2,RCHY1,HLTF,UBR5,SMARCB1,NEK6,COPS4,PMAIP1,XRCC2,RNF111,FNIP2,CHD2,OGG1,TRIP13,SIRT6,EYA3,SUMO3,MCL1,SHISA5,BRCA1,SOX4,CHAF1A,BRCA2,TRRAP,RAD18,TP53BP1,NSMCE1,TNFRSF1A,RAD51B,EME1,COPS6,ZMAT3,EMSY,HERC2,FBXO45,FOXO1,TAF1,CDIP1,FAN1,DDIT4,CEP164,INTS7,APLF,COPS3,MYC,ALKBH8,GTF2H1,TIMELESS,TERF2,PEA15,GTF2H3,CRADD,POLA1,SETD2,LIG4,PSMA1,USP10,ISG15,ASCC3,ATAD5,PALB2,ALKBH3,CDK9,WDR33,MACROD1,BCCIP,USP7,GTF2H2C,NPAS2,RPAIN,MCM9,TERF2IP,BRE,SLX4,ACD,KDM2A,ZSWIM7,UCHL5,WAC,ATRIP,MSH4,CEP63,SPIDR,HTRA2,CTC1,PRPF19,RFC4,PMS1,BRD4,RFC3,PARP2,GNL1,SETD7,POLG2,RAD54B,EXO1,RBBP8,KDM4B,COPS5,HIPK2,NSMCE2,H2AFX,ALKBH1,NFRKB,BRCC3,XRCC4,MUTYH,SMG1,HMGA2,MCM10,XPC,MLH1,RMI1,PSMF1,FOXO3,GIGYF2,MAD2L2,MRPS11,SFR1,ABL1,SNW1,TRIAP1,COPS7B,FBXO31,APEX1,POLK,SMARCAD1,FOXN3,TOP3A,APTX,HIST1H4J,MEN1,CHCHD6,POLR2A,UBC,RPA1,ZRANB3,POLE2,GADD45A,MSH3,AEN,ATM,ZAK,DDIT3 |
| 7.036e-09 | -18.77 | SOX2 (SRY box 2) | protein interactions | 6657 | 346 | 89 | 16036 | 2270 |
TCF12,USP7,CUL7,TRERF1,PAPD4,OLA1,SEC16A,UBR5,PELP1,SMARCB1,PHC2,RPP30,CHD7,ANAPC1,DNAJB6,ZEB1,AHCYL1,ZMYM2,LONP1,CHD9,TUBA1A,SKIV2L2,CUX1,POU2F1,SETD7,NUP214,UBR4,TAF2,PAF1,SMARCC1,CHD3,CCNT1,INTS9,PRPF4,RUNX1,MDN1,BMI1,RBP1,USP15,EP400,NCOR2,UTP14A,ZCCHC8,RFX1,TCF3,HSD17B10,WDR26,QSER1,CDC73,INTS7,MBD2,COPS3,TNPO3,CTR9,ARHGAP1,ANP32B,AKAP11,SOX6,CPSF3L,NOM1,MSI2,GATAD2B,TEAD1,ARID5B,SETD2,XPO5,RNH1,FERMT2,RANGAP1,IMPDH2,ARID1A,SUPT5H,FOXC1,ANXA1,PWP1,POP1,ASCC3,BAZ2B,EHMT2,ARID3B,SRP68,SPEN,SET,TBX3,GPN1,SENP3,NCOR1,ANAPC4,IPO4 |
| 8.258e-09 | -18.61 | BLUM_RESPONSE_TO_SALIRASIB_UP | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_UP | 237 | 63 | 17758 | 2279 |
SEPHS2,CARS,SARS,EGR1,XPC,UBXN1,CSTA,PHGDH,CSNK1A1,COX10,INPP1,FOXO3,AARS,BIRC2,TOM1L1,NAMPT,C6orf48,EIF2S2,ASNS,ANXA7,DUS4L,STC2,BUD31,RELB,SHMT2,AVEN,ULBP1,SKIV2L,PEA15,IFRD1,ATF4,GARS,PSAT1,NARS,GLTSCR2,MTIF2,ANK2,MARS,VIM,SERP1,TARS,ECH1,EIF3H,WARS,TIMM44,YIF1A,EPRS,TRIB3,MTHFD2,GADD45A,DNAJC1,DNAJA3,RIOK3,GLG1,SURF1,TBL1X,PFDN2,CCNB1IP1,PTP4A2,DDX10,GALE,NIT1,COG5 |
| 9.285e-09 | -18.49 | RNA biosynthetic process | biological process | GO:0032774 | 2680 | 441 | 16441 | 2138 |
ZNF292,MYCBP2,ASCC1,PRKAB2,HLTF,CCNL2,ZNF44,NUP160,GABPB2,LPIN1,MGA,SKI,ZNF37A,RPS16,SREBF2,IKZF5,ZFHX3,RNF111,ZNF148,CHD2,KDM5C,MEIS3,ZNRD1,SEH1L,ZNF646,DPF3,HMBOX1,SETD1B,RNMT,NR6A1,EYA3,NFIA,TCEB3,CUX1,RFX2,C5AR1,DENND4A,SAP30BP,ZNF197,GZF1,DDX3X,SKIL,ZNF266,TRRAP,SUPT4H1,CCNT1,ZNF81,HIC2,RUNX1,BMI1,ZNF532,PTPN14,MEF2C,BANP,IFT57,EGR1,TRIP6,ZHX3,KHDRBS1,SIRT7,GTF2IRD1,RSF1,CDC73,CHD5,HR,ZNF586,SCAF1,MYC,ZNF326,MED24,GTF3C3,PRMT5,ZNF518B,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,PRIM2,RREB1,ZNF587,RB1CC1,PRDM16,POLA1,ARID5B,ZNF512B,SMARCD3,ARID1A,NELFA,TRIM37,ONECUT2,SRA1,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,ASCC3,GTF2A1,RPL28,HIF1A,CDK9,SPEN,MED15,ZBTB12,CCDC85B,ZNF160,PURB,CNOT6,NCOR1,ZFHX2,ZNF254,ZNF516,TRERF1,GTF2H2C,NPAS2,ZBTB37,NUP43,FOSL2,SAFB2,RING1,TERF2IP,CHD7,ZNF827,KDM2A,ZKSCAN1,UCHL5,WAC,LPIN2,KMT2A,LSM10,CASP8AP2,SAP30,BRD4,KMT2D,ZNF480,NPM3,ATF7IP2,SATB2,MED16,MEF2D,PNN,SETD7,FGFR1,ZBTB25,VDR,TAF2,BAZ1A,DNTTIP1,MSX2,SMARCC1,KDM4B,ELP2,HIPK2,G6PD,ZNF236,MBTD1,POLR3E,HOXA3,ZBTB11,TROVE2,COMMD10,HMGA2,NCOR2,ZNF786,C10orf2,TCF3,ZNF280C,NFX1,ID2,JMJD6,MYNN,TRIM22,BHLHE40,IKBKAP,FOXO3,MAD2L2,POM121,SFR1,ZNF483,TADA3,ZNF239,SNW1,POLR3D,COMMD9,PTRF,SUV39H2,ELP5,TAF3,YBX3,ZNF710,SOX6,FAM120B,TSHZ1,TTLL5,APEX1,ZNF467,KLF6,FOXC1,UBC,POLR2A,ZFP62,TRIB3,SRCAP,NSD1,BAZ2B,ZNF155,ARID3B,DDIT3,KDM4C,KAT6A,ZNF76,PHF3,GPBP1L1,ATRX,KMT2E,PPARGC1B,POLR1A,CSNK2A1,ZNF107,BCOR,SIRT2,SNAPC4,BIRC2,SMARCB1,SRSF2,PHF5A,YLPM1,JAZF1,HKR1,RELB,ZEB1,POLR3B,ZNF85,ZNF3,ETV1,ZMYM2,TRIP13,CARM1,ELOF1,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,SESN2,ZNF124,TXLNG,ZNF195,PPARG,ZNF414,BAZ2A,ZNF680,MED27,MINA,HDAC8,BRCA1,SOX4,ZSCAN2,KMT2C,ZNF91,TAF9B,MLLT10,PAF1,GLS,UBTF,TCF7L1,GATA6,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,PQBP1,CRCP,DLX2,ZC3H8,ZNF397,BEND6,NOCT,DMTF1,EMSY,SARS,FOXO1,TAF1,PAX2,DPF2,SMAD7,LAMTOR3,HES6,MED13L,BARX2,ZIC2,RLF,ARID1B,DDIT4,ELL,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,GTF2H1,CTR9,TIMELESS,ICE2,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,PAXBP1,TLE3,JMJD1C,ELP3,SETD2,WBSCR22,ZFP14,WWC1,PRDM1,SUPT5H,TCF7L2,NR2F1,PWP1,ATXN7,MYBBP1A,RRAGA,TBPL1,ZNF430,ZFP90,TBL1X,ZBTB24,NR2C2AP,TCF12,ID1,ASH1L,ARID2,RPS29,SMARCA4,PBX1,ZNF83,ZNF709,PELP1,ZNF121,KDM1A,ZSCAN5A,RRN3,NRF1,ZBTB21,CAMTA2,NUP133,ZNF142,ZFP37,RNF2,FHIT,CPSF3,ZNF460,UTP4,MAML3,KDM3B,KAT8,PCGF3,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,NUP214,ZNF251,BATF3,SMAD3,RANBP2,IKZF4,ADNP,SIX5,COPS5,ZNF557,KLF4,ZNF333,CEBPZ,ARNTL,ATG7,ZNF436,SRFBP1,NFRKB,MED20,ZNF18,BRD9,ZNF507,DNAJC2,NIFK,SUPT6H,RFX1,AGO2,PPHLN1,MED18,ATF7IP,FOXP1,ZNF594,ZNF561,POLR1B,DMRT1,PKNOX1,SNAPC5,ARNTL2,TRNP1,MSX1,KDM5B,ZNF821,TEAD1,ZNF654,PSPC1,FOXN3,KDM5A,ZMYM5,SCMH1,ZNF324B,MEN1,ZNF407,POLR3A,RERE,ZNF221,POLR3G,ZNF708,L3MBTL3,TBX3,TAF4,CSRNP1,BCAS3,NCBP2,ZNF32,MYRF,RBPJ,TAF12,POLR1C,NFKBIB,NR2F2 |
| 9.359e-09 | -18.49 | pancreas | COSMIC cancer mutations | pancreas | 17360 | 2259 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,WDR26,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 9.442e-09 | -18.48 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 16643 | 2191 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,CAD,DUS4L,UBR1,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,WDR26,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 1.022e-08 | -18.40 | GCCATNTTG_V$YY1_Q6 | MSigDB lists | GCCATNTTG_V$YY1_Q6 | 405 | 93 | 17758 | 2279 |
MAP2K5,PCNT,CELSR3,ATRX,PRKCSH,PAFAH1B1,WDR13,PPP2R2A,TTI1,GBF1,GIT2,DHX35,SCAF8,METTL16,SRSF2,KDM2A,ATP5G2,SLC39A7,PDS5B,NBEA,ZFP37,CHD2,ETV1,FTSJ3,HN1,SF3A1,ZNF646,HMBOX1,AEBP2,ATF4,MIOS,AKAP8L,LIMA1,KIF15,R3HDM1,POU2F1,DENND4A,RAB10,MAT2A,TJAP1,DDX3X,DYRK1B,ADNP,TP53BP1,LUC7L3,HIC2,INTS9,CCNB1IP1,ZBTB11,PRPF38B,RFX1,MYNN,JMJD6,SSR4,CSNK1A1,FOXP1,ENOX1,GIGYF2,UBE3A,CACNB2,ALKBH8,MED24,CELF1,TTC17,SERBP1,LYPLA2,AP4S1,KIAA1143,FOXN3,TRA2A,PSPC1,PPP1R21,KCNMA1,IDH3G,RAPGEF4,TOP3A,UBE2K,NAPEPLD,POLR2A,UBC,NCDN,EXOC6,DYNC1H1,UBAP1,NSF,HIF1A,HNRNPH3,ADK,PDSS2,KIF1B,N4BP2L2,ANAPC4,LRRC41 |
| 1.068e-08 | -18.35 | JOHNSTONE_PARVB_TARGETS_3_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_DN | 850 | 166 | 17758 | 2279 |
FANCD2,RCHY1,CSPP1,PRR4,NBEAL1,NUP160,COPS4,ATG3,RABGAP1L,PDS5B,IPP,CHD2,NDUFA6,YARS,ZNRD1,CDK6,SEH1L,CSGALNACT2,TMPO,CEP128,TRIM13,SLC3A2,AEBP2,KLHL23,MED27,TCEB3,PACRGL,MINA,KIF15,WDHD1,MCL1,FLVCR1,ODC1,TAF9B,YTHDF2,C1orf122,MLLT10,GLS,SLC7A1,TRMT5,LSM14A,TECPR2,EME1,TPM1,BEND6,BMI1,RFXAP,SARS,MCM6,PRPF31,SLK,C16orf52,ZIC2,QSER1,DOPEY1,C6orf48,SUB1,SLC7A11,ABCA5,COPS3,MBD2,GTF3C3,ALDH18A1,ZCCHC7,N4BP2,NT5E,NAA38,BDNF,ZNF234,IFRD1,EXOSC2,RREB1,POLA1,TRA2A,HAUS6,SETD2,UTP15,ARID1A,TCF7L2,PHF6,ATP9B,UBAP2,MTHFD2,SYNCRIP,FSCN1,BIVM,WDR33,PRKAR2A,N4BP2L2,VMA21,TCF12,ID1,FAM208B,FAM122B,FOSL2,RPAIN,RIOK2,DENR,PRKD3,ASNS,WAC,SOCS6,CPSF3,PXK,LSM10,RFC4,PTBP2,PCMT1,TOR1AIP2,KIAA1586,PNN,SLC35D1,DKC1,NUDT15,SERP1,C1orf174,FBXL5,KPNA3,HNRNPR,TIMM17A,POLR3E,SRFBP1,FKBP5,ANXA2,XRCC4,ECHDC1,MID1,MAP3K13,DBF4,PPHLN1,OPA1,CSNK1A1,MBNL1,RSRC1,RMI1,TMCO6,SACS,SUV39H2,CWC27,DCTN4,EXOSC4,CELF1,HNRNPM,TSHZ1,FAM98A,PSAT1,GINS3,CRIM1,ZMYM5,FERMT2,ARHGEF12,PTK2,EIF5B,NAPEPLD,NOP58,PIK3CB,RPA1,POLE2,TMEM237,ZNF330,SET,RNF138,RBM26,ADK,ZAK,KAT6A |
| 1.228e-08 | -18.22 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 51 | 17758 | 2279 |
ZNF292,ASCC1,AK2,ESCO1,CA11,B4GALT5,SBF2,MYNN,JMJD6,GRINA,FAM13A,RLF,MAP2K3,VPS18,PHC2,TERF2IP,KCTD11,AMPD3,TBC1D22A,CFDP1,EXOSC4,TSPAN14,FUT11,LONP1,SAP30,FAM127A,SLC3A2,PDK1,DDX41,IFNGR2,ATG9A,RNMT,LSM12,ZNF654,MAPK1IP1L,HIST1H2BL,PIK3CB,TBC1D2,GZF1,ZBTB25,ZC3H12A,OXSR1,DDX50,KDM4B,PER1,HK2,CSRNP1,SLC25A26,YEATS2,DDIT3,KDM4C |
| 1.317e-08 | -18.15 | DNA-templated transcription, elongation | biological process | GO:0006354 | 104 | 36 | 16441 | 2138 |
TAF1,POLR1A,IKBKAP,CDC73,ELL,POLR3D,TAF3,GTF2H1,POLR3B,POLR1B,ZNRD1,POLR1E,GTF2H3,SETD2,ELP3,TCEB3,SUPT5H,NELFA,POLR2A,POLR3A,TAF9B,POLR3G,UBTF,PAF1,TAF2,SUPT4H1,ELP2,GTF2A1,CCNT1,CDK9,TAF4,POLR3E,CRCP,NCBP2,TAF12,POLR1C |
| 1.396e-08 | -18.09 | other | COSMIC cancer mutations | other | 15619 | 2080 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,S100A10,CSGALNACT2,ACADS,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,TNFRSF10D,BLMH,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,ELP5,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SCART1,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,CACNA1H,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,NOC3L,COQ3,AGL,FMNL2,SERBP1,HMGCR,RB1CC1,MYO10,CPT1A,ONECUT2,MBNL2,EVI5,NCDN,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,ATG12,FLVCR1,GLS,ZNF622,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,MANBAL,SLC35F2,AKAP13,NUP214,ARL5B,USP36,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,NEDD4,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,MBD6,TATDN1,MMP16,SLC16A10,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SART1,MPI,OLFM2,NDUFAF2,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,VIM,NHSL1,CA5B,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,CHMP2A,FEZ2,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,PMAIP1,NSRP1,RASSF3,RABGAP1L,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SUPT4H1,FIS1,CARS,HERC2,EP400,KHDRBS1,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,DNM3,ZNF516,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,PERP,MALL,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,PES1,TAF2,GNG2,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,DIS3L2,ULBP1,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TRIB3,TOE1,RARS,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,LRRC28,C16orf52,MEX3A,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,PPP2R2A,ZNF83,DENR,DNAJB6,ZDHHC6,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.398e-08 | -18.09 | HDAC11 (histone deacetylase 11) | protein interactions | 79885 | 131 | 44 | 16036 | 2270 |
MYCBP2,UTP14A,WDR74,TTC27,TFIP11,ATG2B,SEC16A,UBR5,KDM1A,NOP56,IGF2BP3,CAD,SNW1,YLPM1,NUP133,DNAJB6,ZNF326,GEMIN4,YBX3,SRRM2,ZMYM2,UTP4,HSD17B12,TMPO,SF3A1,WDR36,PAXBP1,AKAP8L,STAG1,PNN,DKC1,CPT1A,RBM28,SON,POLR2A,PES1,ADNP,DNAJA3,CEBPZ,MDN1,HEATR1,RUNX1,WDR33,PDCD11 |
| 1.467e-08 | -18.04 | single-organism metabolic process | biological process | GO:0044710 | 4618 | 710 | 16441 | 2138 |
GGT1,ASCC1,GNB3,DPH1,AARS2,MRPL10,CACNA1H,HLTF,NT5C3A,HMOX2,SLC6A8,NUP160,ABHD6,SYNJ1,CIAPIN1,AMBRA1,MMP7,SREBF2,ATP5G2,FAAH2,KDM5C,FXN,PPM1K,NRAS,UPP1,EHMT1,MSRB3,STOML2,PYCR1,BRCA2,RAD18,BDH2,FIS1,RBP1,MEF2C,CARS,HERC2,EP400,SLK,SIRT7,PIK3R4,PLA2G12A,CDC73,PITPNM1,YARS2,APLF,ALKBH8,MED24,MRPL21,PRMT5,MAP3K12,AGL,COQ3,PPA1,HMGCR,PEA15,FADS1,GTF2H3,BDNF,COL17A1,ALG6,WDR61,RB1CC1,IDH3G,TYW1,USP10,SMARCD3,ST6GALNAC3,SNAP25,IMPDH2,CPT1A,TRIM37,RDH11,IRS1,GSTO2,NME7,EHMT2,FGFBP1,CDK9,SURF1,BPNT1,WDR33,GALE,SDSL,MAP2K5,TRERF1,GTF2H2C,PAFAH1B1,ATP6V1A,NPAS2,PDK4,NUP43,ST3GAL6,LCLAT1,MCM9,HSPA1A,NDUFB3,ZSWIM7,ACD,PYCRL,WAC,MMP14,ATRIP,GSTA4,NT5C,MSH4,MGLL,MTHFD2L,LYST,PMS1,KMT2D,GARS,PI4KAP2,ATP6V0A1,KCNH3,SLC35D1,NUDT15,MAT2A,FGFR1,PDE8B,GNG2,KDM4B,NSMCE2,PEMT,PAM,BRCC3,YEATS2,MORC2,HMGA2,SERINC5,INSIG2,XPC,TRAK1,JMJD6,ATG2B,IP6K2,RNASEH2B,TGFB2,PSMF1,POM121,TADA3,GATC,SUV39H2,ACOT11,ANXA5,PTGS1,LYPLA2,SPTAN1,DDHD1,FGF9,POLK,LDHA,MRPS10,NXN,PPIP5K2,PDE3B,UBC,MRPL36,RPA1,OXSR1,TRIB3,ETFDH,NSD1,RARS,SRCAP,PXDN,POLE2,STX1A,ACOX1,SRD5A3,GPAM,PSAP,MTMR1,KDM4C,SRM,CYP24A1,TRIM16,PPARGC1B,SLC25A21,SEC16A,COX10,FRRS1,MAP2K3,AMPD3,COPS4,PHKA1,XRCC2,PPCDC,RAN,POLE3,MPST,CDC37,CHD9,ATF4,GCNT2,ABCC4,PPARG,HARS,BAZ2A,HSPA5,GDPD1,COL4A3BP,ATG12,SUMO3,BRCA1,KCNH2,ODC1,DLST,MGST1,GLS,LSS,HPRT1,MSRA,INSIG1,TP53BP1,PER1,TNFRSF1A,RAD51B,ADAM9,USP15,SEPHS2,XYLB,SARS,AOC3,OXNAD1,PRSS3,MAPK8IP3,HSD17B10,LAMTOR3,FAN1,RNF40,MLX,PDE10A,GTF2H1,VAPB,CTR9,TIMELESS,SYNJ2,ALDH18A1,PNPLA3,NT5E,WARS2,TRAPPC9,CAMKK2,USP49,SETD2,OBSCN,TRAPPC6B,CYB5B,ACOXL,VAC14,TCF7L2,PGD,ATXN7,FAM135A,SPAG9,PALB2,IRAK2,TBPL1,CASS4,DTD1,HMBS,GGT7,NAPA,BRSK2,PRKAR2A,BCCIP,USP7,MPI,NDUFA5,SUCLG1,NDUFAF2,LPCAT2,NTSR1,SLC2A1,GPR143,RIPK1,LPCAT3,TNKS1BP1,RPAIN,FDX1,KDM1A,CAD,IDI1,DUS4L,NUP133,GRIN2C,IKBKB,RNF2,HIBCH,AHCYL1,SPIDR,PRMT3,CTC1,PRPF19,SEC24A,KAT8,KDM3B,NARS,RAB7A,CPOX,CA5B,NUP214,ATP5D,EXO1,SMAD3,RANBP2,RBBP8,ABHD3,ATG7,MUTYH,DMGDH,MINK1,AUH,HM13,MAP3K13,AGO2,APRT,VARS,RMI1,SLC25A20,ADH5,NDUFV1,CPNE7,CD44,PCK2,HSD17B12,SMARCAD1,TOP3A,HIST1H4J,PIK3CB,NEU1,SMPDL3B,ZRANB3,GPC2,MSH3,EIF2S1,NDUFAF5,TAF12,NR2F2,GCSH,POLB,CUL4A,PRDX6,PRKCSH,PRKAB2,TNFRSF21,GYG1,PRKCA,AARS,UBR5,LPIN1,SUCLG2,RNF111,DPH6,ME1,FUT11,SEH1L,CSGALNACT2,ACADS,DPF3,SETD1B,ATG9A,ALDH1L2,EYA3,GNG7,FOXRED1,PLCXD2,OSBPL1A,DOT1L,DDAH2,TRRAP,HSDL2,NSMCE1,CFD,CCNB1IP1,TXN2,SPOCK2,SPOCK3,WDR75,DROSHA,LARS2,ST6GAL1,AK6,PID1,DPM3,CCDC47,TGFBR2,CHD5,NDUFS7,FKBP1A,HR,PI4KB,ENTPD5,COPS3,ATIC,MYC,PIGG,SLC16A9,LPCAT1,PRPS1,TERF2,FDFT1,SYNGAP1,PRIM2,PCCA,AOC2,POLA1,RAPGEF4,RDH10,TPRA1,PLCB1,MTR,ANGPTL4,DAGLA,SEC31A,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,NSF,HIF1A,VCAN,D2HGDH,SQLE,DPEP1,PEX13,UMPS,NCOR1,MACROD1,CNDP2,DHCR7,MAP2K4,SMYD3,CPT1C,HS2ST1,LIN28B,HFM1,UROD,NDUFB5,OLA1,RING1,PDE3A,TERF2IP,FLAD1,DECR1,SLX4,ASNS,SHC1,KDM2A,UCHL5,GLYR1,LPIN2,MRPS27,CMPK1,SERPINH1,PNPLA4,KMT2A,RFC4,BRD4,RFC3,PDK1,MTIF2,DLG4,GALK2,MARCH6,SETD7,POLG2,STK10,SERP1,HSD3B7,SNCA,TAMM41,CAMK2D,DCXR,G6PD,H2AFX,LARGE,ALKBH1,SETD6,XRCC4,NOSTRIN,NCOR2,BRAF,C10orf2,B4GALT5,MRI1,TCF3,FARS2,SLC25A12,MLH1,LIAS,GDPD5,INPP1,RPS6KA5,MAD2L2,NEDD4,SFR1,DCTPP1,ABL1,NISCH,PHYKPL,HARS2,COPS7B,NLGN3,MAP3K14,NT5M,MBTPS2,PFKFB4,PSAT1,APEX1,AGPAT4,TBRG4,ADSL,APTX,PTK2,MMAA,POLR2A,ECH1,SLC23A2,RETSAT,COL26A1,COQ9,ATM,NDUFS5,ADK,STK4,KAT6A,IMMP2L,PIGM,LYRM4,MVK,NF1,ATRX,KMT2E,RARS2,SLC52A3,PTPRA,CERS5,FANCD2,RCHY1,PLOD1,BCOR,SIRT2,AHCYL2,SMARCB1,PCYOX1L,MRPS30,RAP1A,CNIH3,KANSL1,JAZF1,ATG3,MYH3,HYAL1,NDUFA6,SLC35C2,SLC27A5,GALNT18,YARS,OGG1,TRIP13,CARM1,PRKACB,TRIM13,SESN2,SIRT6,ITPA,TFPI,GPCPD1,MINA,HDAC8,CAV1,PITPNB,MTHFD1L,KMT2C,ST3GAL5,MPC1,CHAF1A,PAF1,GATA6,HLCS,CTAGE5,ABCC3,GALNT10,EME1,CLU,COPS6,EMSY,LDAH,PIGN,CHST11,AK2,TAF1,SEC24D,PAX2,GPAT3,ALG8,PHGDH,RHBDD1,ETFB,NAMPT,CEP164,P3H1,ISPD,GLTP,MTHFD1,HSD17B14,PDE4A,TSTA3,PPAT,ELOVL6,JMJD1C,ELP3,TBXAS1,PSMA1,LIG4,TMEM241,HERPUD1,ISG15,UBE2E1,MGAT2,MYBBP1A,FDPS,HK2,SLC16A1,TBL1X,PDE9A,PDSS2,AGO3,ASH1L,SLC5A5,CEMIP,PIGH,TNXB,PBX1,ARSJ,PUDP,FARSA,BRE,CBR4,FHIT,TMEM14C,GNG5,HTRA2,AUP1,TMLHE,MCEE,NARS2,ACSL5,COL5A2,PARP2,MRRF,DKC1,EDEM2,WARS,TPK1,RAD54B,PLIN2,HYAL3,ALAD,DUS3L,COPS5,DUSP19,SLC25A11,DISP1,SCARB1,NFRKB,SMG1,BCKDK,TNIK,SH2D3A,SULT1C2,PDE4B,TKFC,CHCHD10,ENOX1,PIP4K2A,GFM2,MAN1A1,MRPS11,PEX7,GART,HAS3,SEC24C,KDELC1,SHMT2,FBL,MICAL3,SLC25A1,KDM6B,GPHN,KDM5B,FGF2,KDM5A,SULT4A1,MARS,MEN1,PDE2A,NAPEPLD,TARS,HSPA1B,MFN2,ALG5,SERINC1,DAGLB,GADD45A,ZAK,MMP16 |
| 1.473e-08 | -18.03 | BLALOCK_ALZHEIMERS_DISEASE_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_UP | 1631 | 284 | 17758 | 2279 |
ARHGAP26,GGT1,CUL4A,PRDX6,ENAH,SLC6A8,NUP160,LPIN1,SREBF2,ZFHX3,ZNF148,CHD2,AVEN,SRRM2,SPAG6,ACADS,DPF3,CUX1,SEMA3F,MCL1,SAP30BP,SPOP,LSM14A,LUC7L3,HSPBAP1,SEMA3C,LPP,BANP,EP400,ZHX3,SLK,KHDRBS1,SIRT7,OPHN1,CENPB,RSF1,KCNJ14,MTUS1,TSPAN2,PI4KB,USPL1,TNPO3,MED24,ANP32B,PABPC1,FDFT1,FADS1,GTF2H3,EXOSC2,IFRD1,RREB1,STAG1,MYO10,AOC2,USP10,ARID1A,TPRA1,ARIH2,EPRS,KPNA1,RPL28,VCAN,SPEN,RIOK3,ZNF160,SENP3,MACROD1,HS2ST1,ZNF254,PPDPF,DDX18,UROD,DDR2,NUP43,POP5,AP1B1,PDE3A,NOP56,PHC2,KDM2A,SHC1,NT5C,SSBP1,MSH4,CDK12,LYST,SAP30,BRD4,MTIF2,ARHGEF10,MARCH6,DSP,STK10,FGFR1,MAT2A,DCBLD2,ZFAND3,FBXL5,BAZ1A,CDC16,SMARCC1,HIPK2,G6PD,ZNF236,H2AFX,LARGE,SLC4A7,ANXA2,TBXA2R,NOLC1,TROVE2,MID1,BAG1,NCOR2,SCAMP3,TCF3,NFX1,SF3A3,JMJD6,TGFB2,RPS6KA5,INPP1,FOXO3,PSMF1,PHLDA2,ABL1,PTRF,SUV39H2,NEBL,ARHGAP1,PTGS1,MAP3K14,HNRNPM,NUDC,PXN,APTX,IL6R,OASL,ANXA1,TRIB3,SRCAP,ZDHHC11,BAZ2B,HELZ,HNRNPH3,RABEP1,KAT6A,MVK,UBN1,SLC25A21,PLOD1,SIRT2,BIRC2,MAP2K3,DST,AMPD3,ATG3,IPP,ZMYM2,OGG1,LONP1,TRIM14,CARM1,MPST,SRPK2,PTPRK,LAMA4,ZBTB17,DSC3,FLNC,RBCK1,FBXW4,ZNF195,SLC38A1,SIRT6,BAZ2A,GMFB,SUMO3,LAMA2,COTL1,BRCA1,SGK2,ODC1,TIMM44,LSS,TCF7L1,INSIG1,HLCS,PER1,TNFRSF1A,GALNT10,CLU,SLC12A7,TTN,AK2,FOXO1,UBXN1,ZFP36L1,NAMPT,ZNF358,TIMELESS,GTF2H1,CRADD,LAMC1,ELOVL6,TLE3,SETD2,TCF7L2,NR2F1,TBC1D2,UBAP2,SPAG9,FDPS,TBL1X,HMBS,PTP4A2,IFITM2,PDSS2,PRKAR2A,USP7,SART1,FEZ2,SLC2A1,RNF24,PIBF1,PPP1R9A,PELP1,MET,HTRA2,SEC24A,PRAME,ARHGAP17,AKAP8L,SSFA2,TUBA1A,GLTSCR2,SFSWAP,R3HDM1,SLC35F2,AKAP13,NUP214,TJAP1,LMBR1L,IKZF4,TIMM17A,HSPB8,SCARB1,RNF130,NFASC,TSPAN5,MUTYH,PARD3,DBF4,H2AFJ,CSNK1A1,POGZ,PIP4K2A,IQGAP2,FAM50A,CTNNBL1,SEC24C,IFIT5,SHMT2,POLR1B,CD44,C12orf4,SLC25A1,MSX1,FOXN3,KDM5A,PSMC3IP,ZMYM5,TOP3A,ASAP3,RANGAP1,PALLD,EIF5B,TPD52L2,SET,ZNF32,RBPJ,POLR1C,ITGB4,MMP16 |
| 1.506e-08 | -18.01 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 443 | 99 | 17758 | 2279 |
FEZ2,LUZP1,ACTG1,PAFAH1B1,MFGE8,SPATS2L,TUBB6,FOSL2,IKBIP,ARSJ,PTPRG,PRKCA,PABPC4,PRKD3,JAG1,CCDC50,DHX33,ZEB1,MET,VCL,CDK6,FLNC,PHLDB2,ANTXR2,ABCC4,SSFA2,KATNAL1,PTPRM,WLS,UPP1,ANKRD33B,TFPI,AKAP12,MSRB3,VIM,CAV1,STK10,DCBLD2,GNAI1,SMAD3,GLS,GNG2,ARHGAP21,AHNAK2,TRAF3,ANXA2,TPM1,NRP1,TNFRSF10D,ECHDC1,TMEM158,CEP170,MID1,HMGA2,ITPRIP,TRIO,RTN4,ZIC2,IGF2BP2,TGFB2,TGFBR2,INPP1,CMTM3,IGF2BP3,SH2B3,NAV1,SACS,MCAM,PTRF,ASAP1,PVRL3,ANXA5,CD44,CAV2,FMNL2,NT5E,NAV3,ARNTL2,BDNF,TRNP1,PDE4A,LAMC1,IFNGR2,CRIM1,TEAD1,MAP7D1,EHBP1,FOXC1,NR2F1,ANXA1,NAP1L5,SPAG9,PXDN,GADD45A,FSCN1,IRAK2,ATM,CORO2B,HRH1 |
| 1.509e-08 | -18.01 | neoplasm | COSMIC cancer mutations | neoplasm | 15558 | 2073 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,S100A10,CSGALNACT2,ACADS,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,TNFRSF10D,BLMH,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,ELP5,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,QSER1,EVPL,NAMPT,RNF141,CCDC124,ZCCHC7,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,CACNA1H,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,NOC3L,COQ3,AGL,FMNL2,SERBP1,HMGCR,RB1CC1,MYO10,CPT1A,ONECUT2,MBNL2,EVI5,NCDN,CLASRP,LEMD3,SURF1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,ATG12,FLVCR1,GLS,ZNF622,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,MANBAL,SLC35F2,AKAP13,NUP214,ARL5B,USP36,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,NEDD4,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,MBD6,TATDN1,MMP16,SLC16A10,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SART1,MPI,OLFM2,NDUFAF2,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,VIM,NHSL1,CA5B,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,NOVA2,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,CHMP2A,FEZ2,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,PMAIP1,NSRP1,RASSF3,RABGAP1L,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SUPT4H1,FIS1,CARS,HERC2,EP400,KHDRBS1,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,DNM3,ZNF516,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,PERP,MALL,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,PES1,TAF2,GNG2,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,DIS3L2,ULBP1,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TRIB3,TOE1,RARS,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,LRRC28,C16orf52,MEX3A,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,PPP2R2A,ZNF83,DENR,DNAJB6,ZDHHC6,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,GNG7,EYA3,NOL8,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,TXN2,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,SCAF11,ADARB1,SYNGAP1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.670e-08 | -17.91 | PARENT_MTOR_SIGNALING_UP | MSigDB lists | PARENT_MTOR_SIGNALING_UP | 545 | 116 | 17758 | 2279 |
ARHGAP26,PPDPF,PHF3,TRPM2,MAP2K5,PTPRA,PDK4,HECTD3,MKS1,TBCCD1,PLOD1,RSL1D1,FAM13A,SLC6A8,GBF1,GIT2,AMBRA1,RTN1,SREBF2,THADA,TBC1D22A,SLC39A7,NCKIPSD,MRPS27,ZNF142,AHCYL1,SLC35C2,CDK12,EVL,SKAP2,TFPI,C1QTNF1,ATXN1,LAMA2,AKAP13,DLST,SERGEF,DHX57,SUPT4H1,KDM4B,ALAD,ZNF557,TECPR2,TNFRSF1A,INTS9,IFT140,VPS13D,COMMD10,DNAJA4,FN1,SUPT6H,ST6GAL1,NFX1,C14orf159,MED18,ATF7IP,IP6K2,LIAS,RBM19,PHGDH,CSNK1A1,PSMF1,MFSD10,DDIT4,ATXN7L1,FKBP1A,NPRL2,NOP16,TANK,VAPB,SHMT2,RDX,PCK2,CD44,LYPLA2,CLK2,NIPSNAP1,USE1,GTF2H3,CRADD,GPHN,PRIM2,PDE4A,TEAD1,KDM5A,PCCA,ZMYM5,TOP3A,ZNF324B,C11orf49,YIPF3,OASL,SUPT5H,EIF5B,SYT1,PLCB1,VPS13C,NSD1,SPAG9,HELZ,EHMT2,TTC38,ACOX1,FDPS,MSH3,SURF1,BCAS3,GLG1,SVIL,NCBP2,DHCR7,XPO6,DOCK6,PRKAR2A,SGSM3,KAT6A |
| 1.688e-08 | -17.90 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | MSigDB lists | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | 24 | 15 | 17758 | 2279 |
CARS,FARSA,RARS,EPRS,SARS,GARS,NARS,HARS,MARS,VARS,YARS,AARS,PPA1,TARS,WARS |
| 1.696e-08 | -17.89 | ligase activity | molecular function | GO:0016874 | 395 | 92 | 16491 | 2164 |
MYCBP2,BIRC6,SUCLG1,RARS2,AARS2,HECTD3,RCHY1,RNF43,HLTF,UBR5,AARS,BIRC2,RING1,CAD,FARSA,ASNS,UBR1,ATG3,FAAH2,TRIML2,RNF111,SUCLG2,RNF2,TTC3,DPH6,SLC27A5,MTHFD2L,YARS,PRPF19,ACSL5,NARS2,TRIM13,GARS,RBCK1,NARS,HARS,BRCA1,MTHFD1L,MARCH6,UBR4,WARS,UBE3D,RANBP2,HLCS,RAD18,SH3RF1,NSMCE2,NSMCE1,ATG7,TRAF3,RNF130,CCNB1IP1,XRCC4,MID1,TRIM36,CARS,HERC2,SARS,LARS2,NFX1,FARS2,VARS,LIAS,TRIM22,NEDD4,YARS2,TTLL11,RNF40,GART,UBE3A,GATC,PPIL2,LTN1,HARS2,LRSAM1,CNOT4,MTHFD1,MARCH9,WARS2,TTLL5,PCCA,LIG4,MARS,TRIM37,TARS,ARIH2,EPRS,RARS,MTHFD2,HERC1,RNF138,RNF114 |
| 1.699e-08 | -17.89 | MEMBRANE_ENCLOSED_LUMEN | MSigDB lists | MEMBRANE_ENCLOSED_LUMEN | 444 | 99 | 17758 | 2279 |
NPAS2,PPARGC1B,TFIP11,MRPL10,SMARCA4,SNAPC4,RPAIN,GIT2,SMARCB1,NOP56,RPP30,MPHOSPH10,SRSF2,NSRP1,JAZF1,INTS12,ZNF148,CPSF3,OGG1,HTRA2,TIMM50,SAP30,NR6A1,GNL3,NOL8,NOL6,ATXN1,WDHD1,HDAC8,MED16,DKC1,POLG2,CHAF1A,TIMM44,UBTF,GEMIN5,TAF2,TRRAP,ELP2,SMARCC1,TP53BP1,CCNT1,DNAJA3,HIPK2,ARNTL,INTS9,NOLC1,BCKDK,TAF1,PRPF31,HES6,MED18,RSF1,IKBKAP,NOL3,OPA1,ZNF346,ARID1B,ETFB,MRPS11,ABL1,SUB1,DDX56,INTS7,GTF2H1,GTF3C3,GEMIN4,POLR1E,PNMA1,CPSF3L,NOM1,TOP1,SCAF11,PPP1R9B,DDX24,POLA1,ELP3,SMARCD3,MRPS10,APTX,ARID1A,MEN1,OASL,SYMPK,NOP58,POLR2A,RPA1,POLR3G,POP1,MYBBP1A,HIF1A,ZNF330,INTS5,SRP68,CDK9,TAF4,RBPJ,TAF12,POLR1C |
| 1.699e-08 | -17.89 | ORGANELLE_LUMEN | MSigDB lists | ORGANELLE_LUMEN | 444 | 99 | 17758 | 2279 |
NPAS2,TFIP11,PPARGC1B,MRPL10,SMARCA4,SNAPC4,RPAIN,GIT2,NOP56,SMARCB1,RPP30,MPHOSPH10,SRSF2,NSRP1,JAZF1,INTS12,ZNF148,CPSF3,OGG1,HTRA2,TIMM50,SAP30,NR6A1,GNL3,NOL8,NOL6,WDHD1,ATXN1,HDAC8,MED16,DKC1,POLG2,CHAF1A,TIMM44,GEMIN5,TAF2,UBTF,TRRAP,SMARCC1,ELP2,TP53BP1,CCNT1,HIPK2,DNAJA3,ARNTL,INTS9,NOLC1,BCKDK,TAF1,PRPF31,HES6,MED18,RSF1,ZNF346,NOL3,IKBKAP,OPA1,ARID1B,ETFB,MRPS11,ABL1,SUB1,DDX56,INTS7,GTF2H1,GTF3C3,GEMIN4,PNMA1,POLR1E,CPSF3L,TOP1,NOM1,SCAF11,PPP1R9B,DDX24,POLA1,ELP3,MRPS10,SMARCD3,APTX,ARID1A,OASL,MEN1,SYMPK,NOP58,POLR2A,RPA1,POLR3G,POP1,MYBBP1A,HIF1A,ZNF330,INTS5,CDK9,SRP68,TAF4,TAF12,RBPJ,POLR1C |
| 1.726e-08 | -17.87 | Gene Expression | REACTOME pathways | R-HSA-74160 | 1330 | 247 | 8202 | 1117 |
EIF3C,PRKAB2,RARS2,POLR1A,DCP1B,PLRG1,AARS2,PRKCA,NUP160,AARS,SNAPC4,EDC3,ZNF37A,SKI,SRPRB,SRSF2,RPS16,PHF5A,HKR1,RNF111,POLR3B,RAN,TRMT10A,YARS,ZNF3,ZNRD1,SEH1L,CARM1,SF3A1,METTL1,SNU13,CHD9,ZNF124,SESN2,AEBP2,ZNF195,ZNF680,BAZ2A,PPARG,RNMT,NR6A1,HARS,MED27,TSN,TCEB3,NFIA,KRBOX4,HIST1H2BL,ZNF767P,SAP30BP,ZNF197,CLNS1A,TAF9B,GEMIN5,UBTF,SKIL,GLS,SUPT4H1,ZNF266,TRMT5,CHD3,CCNT1,E2F4,CRCP,PRPF4,TSEN2,TNRC6A,CARS,CTU2,SARS,DROSHA,LARS2,TAF1,AK6,SMAD7,LAMTOR3,SMG7,ZFP36L1,PDCD7,SSR4,PARN,YARS2,DDIT4,IGF2BP3,ELL,EIF2S2,ZNF354A,ZNF586,TRMT13,MBD2,MYC,ALKBH8,GTF2H1,MED24,GTF3C3,IGF2BP1,GEMIN4,PRMT5,CNOT4,POLR1E,PPA1,PABPC1,ADARB1,GATAD2B,ZNF675,GTF2H3,EXOSC2,ZNF234,WARS2,ZNF587,XPO5,TYW1,EIF4A2,ZFP14,PSMA1,SMARCD3,NELFA,SUPT5H,NR2F1,ZNF655,POP1,ZNF425,EPRS,GTF2A1,RPL28,EHMT2,CDK9,SRP68,MED15,ZNF160,RRAGA,SURF1,ZNF430,CDKAL1,ZFP90,CNOT6,TBL1X,NCOR1,SRP14,AGO3,NR2C2AP,ZNF254,ZNF706,GTF2H2C,RPS29,LAGE3,PPP2R2A,POP5,NUP43,ZNF709,TNKS1BP1,HNRNPA3,HSPA1A,RPP30,FARSA,RRN3,BCAS2,ZKSCAN1,NUP133,ETF1,ZFP37,CPSF3,TRMT12,ZNF460,LSM10,PRPF19,SAP30,MAML3,NARS2,GARS,NARS,EIF3J,ZNF480,POU2F1,MED16,NUP214,EIF3H,WARS,SMAD3,TAF2,VDR,RANBP2,HNRNPR,ZNF333,G6PD,ZNF557,HIPK2,POLR3E,ZNF436,H2AFX,PUS1,FUS,MED20,ZNF18,EIF2B3,ZNF589,SMG1,ZNF786,NCOR2,AGO2,SF3A3,FARS2,IGF2BP2,VARS,ZNF691,PSMF1,POM121,ZNF483,SNW1,POLR3D,CTNNBL1,ZNF561,PTRF,TAF3,HIST2H3D,HARS2,UPF2,POLR1B,EXOSC4,ZNF710,SNAPC5,HNRNPM,TEAD1,ZNF324B,MARS,HIST1H4J,MEN1,EIF5B,TARS,UBC,POLR3A,POLR2A,HSPA1B,ZNF221,POLR3G,ZNF708,RARS,ZNF155,ZBTB8OS,ADAT2,SET,TAF4,EIF2S1,NCBP2,RBPJ,TAF12,POLR1C |
| 1.770e-08 | -17.85 | regulation of cellular macromolecule biosynthetic process | biological process | GO:2000112 | 3795 | 596 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,TOM1L1,SREBF2,ZFHX3,IKZF5,WIZ,ZNF148,FNIP2,KDM5C,HMBOX1,EIF4E3,GNL3,EHMT1,NFIA,KRBOX4,RFX2,ZNF197,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,EPM2AIP1,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ABCA7,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,RPS6KB1,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,UQCC1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ZNF124,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ETF1,ZFP37,RNF2,PRMT3,CTC1,KAT8,KDM3B,PCGF3,DDX41,ENC1,ZNF251,PUM3,EIF3H,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,EIF2B3,ZNF589,PKIB,ZNF507,ESCO1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,SELT,SNAPC5,TRNP1,ZNF654,SMARCAD1,FOXN3,ZMYM5,HIST1H4J,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,GABPB2,AARS,MGA,LPIN1,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,LSM14A,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,LARS2,ZHX3,ANKRD17,CENPB,PID1,GTF2IRD1,CHD5,IGF2BP3,HR,ZNF586,MYC,IGF2BP1,TERF2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,EPRS,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,PAIP2,TERF2IP,CHD7,ZNF827,KDM2A,SHC1,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,MTIF2,SATB2,MED16,PNN,SETD7,SERP1,ERC1,ZBTB25,SNCA,BAZ1A,VDR,MSX2,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,GIGYF2,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,LARP4B,YBX3,MBTPS2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,IREB2,BRWD3,DDIT3,KAT6A,ZNF76,EIF3C,KMT2E,ATRX,UBN1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,ELOF1,ZBTB17,DEAF1,TRIM13,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,CC2D1B,DNAJC1,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,TNRC6A,EMSY,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,IGF2BP2,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,KDM5A,PSPC1,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,EIF5B,CTIF,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,NFKBIB |
| 1.962e-08 | -17.75 | HELICASE_ATP_BIND_1 | prosite domains | PS51192 | 108 | 36 | 11866 | 1504 |
EP400,DDX18,ATRX,HFM1,DDX19A,SMARCA4,HLTF,DDX60L,DHX35,CHD5,CHD7,DDX56,DHX37,DHX33,DDX31,CHD2,SKIV2L,CHD9,DDX28,DDX41,DDX24,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,ZRANB3,RAD54B,DDX3X,SRCAP,ASCC3,DDX50,CHD3,DDX10 |
| 1.962e-08 | -17.75 | HELICASE_CTER | prosite domains | PS51194 | 108 | 36 | 11866 | 1504 |
EP400,ATRX,DDX18,HFM1,DDX19A,SMARCA4,HLTF,DHX35,CHD5,DDX60L,CHD7,DDX56,DHX37,DHX33,CHD2,DDX31,SKIV2L,CHD9,DDX28,DDX24,DDX41,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,RAD54B,ZRANB3,DDX3X,SRCAP,ASCC3,DDX50,CHD3,DDX10 |
| 2.030e-08 | -17.71 | breast-carcinoma | COSMIC cancer mutations | breast-carcinoma | 15843 | 2104 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,FAN1,ZIC2,C1orf52,SUB1,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,MBTD1,CBWD1,SLC4A7,TRAF3,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,SMG7,QSER1,EVPL,NAMPT,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,UBE2E1,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,MEF2C,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,PLEKHA4,ZCCHC14,RFC4,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,TCTN1,CDHR3,UBTF,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,UBAP2,MYBBP1A,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,ZC3H12A,ADNP,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,EHBP1,ZNF850,ATP9B,CAT,ASCC3,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,TBCK,FNBP1L,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,ZBTB8OS,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,CGN,PRKAB2,PLRG1,ENAH,IKBIP,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,FUT11,DPF3,SLC38A6,NOL8,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.107e-08 | -17.68 | cervix | COSMIC cancer mutations | cervix | 12381 | 1698 | 17775 | 2278 |
GGT1,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,SBF2,CCNL2,SLC6A8,ZNF44,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,LETM2,AP1M1,KDM5C,MSANTD2,SRRM2,ZNRD1,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,WDHD1,C5AR1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,LRRC40,SYNGR2,DIRAS1,RIOK1,RUNX1,VASH2,ZNF532,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,SAMD3,ANGPT2,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,RAB11FIP4,C16orf95,PAFAH1B1,C16orf45,DDR2,CD99L2,FAM122B,ST3GAL6,LCLAT1,CBWD5,MCM9,RPGRIP1L,CD96,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,MGLL,ZC3H3,LYST,PMS1,KMT2D,ZNF480,PI4KAP2,SLCO6A1,FAM171A2,PCNXL2,MEF2D,KCNH3,GSTCD,SLC35D1,DSP,VPS53,MAT2A,SLC39A14,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,ARL13B,POLR3E,CAMKMT,HOXA3,CENPBD1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,POLR3D,TAF3,CFDP1,UNC13A,ANXA5,LTN1,RAPGEFL1,ACTR3B,C15orf41,SAMD4A,PNMA1,SPTAN1,VPS37A,DDX24,ZC3H18,NXN,RSBN1,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,SRD5A3,BMP4,SORCS2,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,ANKRD11,HKR1,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,FMNL3,ATF4,MIOS,PPARG,CDK4,ANK2,TSN,SUMO3,PSMG1,LAMA2,KCNH2,CRYBG3,LSG1,C1orf122,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,MAPK8IP3,FAN1,ZIC2,ARID1B,SPIRE1,MLX,ZNF358,CEP290,VPS72,NDRG4,VAPB,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,CYB5B,TCF7L2,PRPF40B,GRIK4,CASS4,SIL1,DTD1,GGT7,SH3PXD2A,USP7,SART1,ID1,OLFM2,PAPD4,SUCLG1,UPK3B,ARID2,OSBPL9,SLC2A1,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,URB1,PLXNB1,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,KIRREL2,RAB7A,VIM,NHSL1,EIF3H,ZNF251,EXO1,IFT81,LMBR1L,ATG7,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,NR2F2,XPO6,KIF1B,C6orf223,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,OSBP2,C2orf76,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,PLCXD2,GNAI1,SPOP,OSBPL1A,DOT1L,TRRAP,LSM14A,SH3RF1,CCNT1,HSPBAP1,ARL6IP5,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,SPOCK3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,SSR4,C1orf50,NDUFS7,MTUS1,TECTA,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,CAV2,FDFT1,IFNGR2,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,SLC26A11,MTR,ZNF850,ATP9B,CAT,ASCC3,C6orf141,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,NCOR1,CNDP2,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PTPRG,CORO6,PABPC1L,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,ERC1,SERP1,HSD3B7,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,MBTD1,LARGE,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,DNAJC22,OPA1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,GUF1,SLC23A2,ZFP62,RETSAT,DDX50,ZNF155,IREB2,COQ9,ATM,SVIL,APAF1,ADK,IPO4,IMMP2L,PIGM,ZNF76,LETM1,EIF3C,ATRX,RARS2,SLC52A3,PCYOX1L,DST,CNIH3,JAZF1,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ARRDC3,TFPI,VWCE,MINA,KSR2,PITPNB,MTHFD1L,KMT2C,ST3GAL5,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,SCART1,ZCCHC8,UBXN1,PCSK7,SMG7,QSER1,EVPL,TIMM10,RNF141,ELL,ISPD,CCDC124,PRF1,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,PFDN2,TBL1X,IFITM2,FNBP1L,TBCK,PDE9A,N4BP2L2,NR2C2AP,DMXL2,TCF12,PSTPIP2,TMEM183A,TNXB,SMARCA4,TBCCD1,COBLL1,TMEM177,SPATS2,ARSJ,PIBF1,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,NVL,PPFIBP1,SNTG2,ITGAX,VCL,TMEM120B,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,METTL2A,GRHL3,ATXN1,DKC1,EDEM2,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,DUS3L,HNRNPR,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,TMEM101,RNF130,BRD9,SMG1,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,STC2,TMEM99,LDLRAD3,ERI3,PKNOX1,MICAL3,RPS6KB2,MARCH9,KDM6B,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,WDR35,AGTPBP1,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,RASSF3,FAAH2,RABGAP1L,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,PACRGL,RFX2,AKAP12,MSRB3,PLEKHM3,MCL1,DCUN1D5,TMSB4X,DDX3X,BRCA2,ZNF266,SUPT4H1,MEF2C,HERC2,CARS,EP400,TRIP6,SIRT7,PRAF2,NHS,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,SERBP1,HMGCR,FADS1,GTF2H3,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,GTF2A1,CLASRP,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,PDK4,MYH9,AGAP6,NECAP1,SAFB2,EEA1,STAM,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,FMNL1,ATRIP,NT5C,GSTA4,CEP63,MTHFD2L,PERP,GARS,KRT7,FAM111B,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,PEMT,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,C1orf226,SF3A3,WDR37,JMJD6,AKT1S1,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,ERICH1,POLK,FRA10AC1,FAM126B,ZNF467,DDX49,FOXC1,RPA1,KISS1R,ETFDH,TRIB3,BAZ2B,PXDN,POLE2,PLPPR2,SLCO5A1,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,KDM4C,ANAPC4,SRM,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,MFGE8,HECTD3,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,PPCDC,UBAP2L,ZNF85,RAN,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,FLNC,METTL1,CHD9,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,SKIV2L2,ZNF414,KATNAL1,COL4A3BP,NOL6,ATG12,BRCA1,ZNF91,FLVCR1,CCDC28B,PEX1,KIF16B,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,XYLB,SEPHS2,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,HOMER2,BCS1L,RNH1,MEX3B,ZNFX1,SUPT5H,NR2F1,VAC14,PGD,PWP1,SPAG9,ITPRIPL1,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,TESC,PRKAR2A,RNF114,KCTD7,LPCAT2,RBFOX2,GPR143,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,UBR1,FSIP2,DNAJB6,ARMC5,ZDHHC6,HIRIP3,ZFP37,ETF1,HIBCH,ANO8,CORO1A,AKNAD1,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,THSD4,TMEM123,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,ABHD3,ITGA2,ZNF436,TSSC1,NFASC,ZNF18,PPIL3,PKIB,ATXN7L2,UNC13D,MAP3K13,FAM46B,MAP1S,C14orf159,ARFIP2,ZNF346,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,HIST2H3D,PRICKLE2,GREB1,CD44,PCK2,FBXO31,HSD17B12,GINS3,ADAMTSL3,TEX14,DHX34,PEAR1,RAP1GDS1,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,POLR3G,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,SET,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRDX6,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RPS16,VPS52,RNF111,ME1,PRADC1,CEP135,MEIS3,TBC1D8,DPF3,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,SEMA3F,MAK16,SH3GL1,SKIL,HSDL2,ZNF81,VPS13D,GREB1L,DNAH2,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ASAP1,SLC16A9,SAMD13,IGF2BP1,LPCAT1,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,PTPN12,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,SRRD,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,UMPS,IQSEC2,MAP2K4,ZFHX2,RTTN,PTCD2,TBKBP1,AMOTL1,TRPM2,CCDC58,LIN28B,SPATA2L,ZBTB37,URB2,HFM1,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,PDE3A,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,KDM2A,UCHL5,GLYR1,VGF,NBEA,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,HTR7,YIPF2,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,MRI1,TCF3,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,IKBKAP,GDPD5,REEP5,TMCO6,NEDD4,ZNF483,RGS17,PTRF,NISCH,TRIAP1,PMPCA,HARS2,UPF2,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,FAM120B,TSHZ1,WDFY3,C19orf43,FZD3,KCNMA1,WDR18,OASL,MMAA,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,MYOM2,BRWD3,SLC43A1,LRRC41,SLC37A3,MVK,PHF3,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,SNAPC4,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,THADA,YLPM1,LONRF2,ATG3,ZNHIT6,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,SLC27A5,NDUFA6,TRIM14,LONP1,LAMA4,ZBTB17,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,LVRN,GPCPD1,HDAC8,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,ZNF397,TNRC6A,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,XPO7,C11orf54,ETFB,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,NRIP1,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,SLC9B2,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CCDC50,CAMTA2,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,HN1,TMLHE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAD54B,WARS,ZC3H12A,ADNP,COPS5,DISP1,SCARB1,HEATR1,USP11,TSPAN5,TNIK,SH2D3A,C17orf80,DBF4,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,MFSD10,SFI1,MAN1A1,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,SHMT2,TTC17,AMOT,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,TARS,MFN2,RERE,ZNF708,MPP7,ZNF330,CUL2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,HRH1 |
| 2.211e-08 | -17.63 | regulation of nitrogen compound metabolic process | biological process | GO:0051171 | 4191 | 650 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,NOS1AP,SKI,ZNF37A,TOM1L1,SREBF2,ZFHX3,IKZF5,NSRP1,WIZ,ZNF148,FNIP2,KDM5C,HMBOX1,EIF4E3,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,ZNF197,STOML2,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,RUNX1,ZNF532,P2RY11,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ABCA7,RBM20,APLF,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,ZNF675,GATAD2B,FADS1,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,TASP1,KPNA1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,PSMF1,MBNL1,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,UQCC1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,HNRNPLL,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SLC25A23,TMPO,PTPRK,CHD9,RBCK1,ZNF124,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,BRCA1,ODC1,ZNF91,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,CLK1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,PRMT3,CTC1,PRPF19,KAT8,KDM3B,PCGF3,DDX41,ENC1,ZNF251,PUM3,EIF3H,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,EIF2B3,ZNF589,PKIB,ZNF507,ESCO1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ZNF594,ZNF561,TMEM161A,HIST2H3D,SELT,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,DHX34,HIST1H4J,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,CUL4A,PRKCA,GABPB2,UBR5,AARS,MGA,LPIN1,GIPR,RNF111,CHD2,ME1,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SON,SAP30BP,SPOP,GZF1,DOT1L,SKIL,DDAH2,TRRAP,CCNT1,LSM14A,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,DROSHA,JUP,EGR1,LARS2,ZHX3,ANKRD17,CENPB,PID1,GTF2IRD1,CHD5,IGF2BP3,HR,ENTPD5,ZNF586,NOVA2,MYC,IGF2BP1,LPCAT1,TERF2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,HIF1A,SPEN,MED15,ZBTB12,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,PAIP2,TERF2IP,CHD7,ZNF827,SLX4,KDM2A,SHC1,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,MTIF2,SATB2,MED16,PNN,SETD7,SERP1,ERC1,ZBTB25,SNCA,VDR,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NOSTRIN,NCOR2,TCF3,ZNF280C,NFX1,RCAN1,MYNN,MLH1,IKBKAP,RPS6KA5,GIGYF2,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,YBX3,LARP4B,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,IREB2,APAF1,BRWD3,DDIT3,KAT6A,ZNF76,EIF3C,UBN1,NF1,ATRX,KMT2E,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,YLPM1,JAZF1,GPR87,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,SRPK2,ZBTB17,DEAF1,TRIM13,TXLNG,ZNF195,SIRT6,ZNF680,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,TAF1,PAX2,DPF2,MED13L,DDIT4,NAMPT,TOX4,RNF141,ELL,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,SMARCA4,PBX1,ZSCAN5A,RRN3,BRE,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,SCARB1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,IGF2BP2,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,EIF5B,CTIF,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,NFKBIB,HRH1 |
| 2.214e-08 | -17.63 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 16389 | 2163 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,PDS5B,LYRM5,HRG,AVEN,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,CAD,DUS4L,UBR1,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,INTS12,C16orf58,MSH4,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,WDR26,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,SLC38A6,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 2.371e-08 | -17.56 | catalytic activity | molecular function | GO:0003824 | 5611 | 850 | 16491 | 2164 |
PTP4A1,GGT1,GNB3,ADAM19,DCP1B,AARS2,NAT10,TUBE1,HLTF,CHAC1,NT5C3A,HMOX2,ABHD6,SYNJ1,CIAPIN1,MMP7,SREBF2,NEK6,SYN2,FAAH2,KDM5C,ZNRD1,FXN,FTSJ3,CDK6,PPM1K,RNMT,KLHL23,GNL3,UPP1,PTPRM,EHMT1,KIF15,MSRB3,ABCC2,MCM2,PYCR1,DDX3X,BRCA2,SSU72,RAD18,BDH2,RIOK1,DIRAS1,HERC2,CARS,EP400,SLK,TRIO,SIRT7,PIK3R4,PLA2G12A,RSF1,PARN,YARS2,ABCA7,DDX56,UBE3A,DHX37,APLF,MCM5,ALKBH8,MED24,PRMT5,COQ3,MAP3K12,AGL,PPA1,HMGCR,FADS1,GTF2H3,ALG6,MYO10,TYW1,EIF4A2,IDH3G,USP10,ATAT1,ST6GALNAC3,IMPDH2,CPT1A,TRIM37,USP46,ABCF1,RDH11,DYNC1H1,TASP1,GSTO2,EHMT2,NME7,CDK9,SURF1,GPN1,CNOT6,SENP3,BPNT1,PLPP6,C18orf25,GALE,SDSL,DNM3,MAP2K5,ABCA3,DDX18,SUGCT,ATP6V1A,PDK4,DDR2,MYH9,ISG20L2,TUBB6,ST3GAL6,LCLAT1,HSPA1A,MCM9,NDUFB3,RPP30,PRKD3,ABCA12,ERI1,PYCRL,MMP14,GSTA4,NT5C,MSH4,PXK,MGLL,TRMT12,MTHFD2L,PMS1,KMT2D,GARS,STAMBP,PI4KAP2,ATP6V0A1,ADAM32,KCNH3,NUDT15,FKBP3,FGFR1,MAT2A,PDE8B,TAF2,FBXL5,KDM4B,PEMT,HIPK2,METTL6,NSMCE2,CAMKMT,POLR3E,PAM,RPS6KB1,BRCC3,METTL2B,RAB30,TRIM36,HMGA2,JMJD6,IP6K2,TRIM22,RNASEH2B,TGFB2,TADA3,TTLL11,NPRL2,POLR3D,GATC,SUV39H2,ACOT11,LTN1,PTGS1,FBXL19,LYPLA2,DIS3L2,DDHD1,DDX24,CLYBL,POLK,USP42,LDHA,NXN,PPIP5K2,UBE2K,PDE3B,DDX49,ANXA1,OXSR1,TRIB3,NSD1,RARS,TOE1,SRCAP,ETFDH,PXDN,POLE2,PLPPR2,HERC1,ACOX1,SRD5A3,PTPN4,AEN,GPAM,MTMR1,NUDT22,ANAPC4,KDM4C,SRM,CYP24A1,POLR1A,HECTD3,CSNK2A1,RNF43,COX10,BIRC2,FRRS1,MAP2K3,ABL2,AMPD3,COPS4,DHX33,PHKA1,TRMU,XRCC2,TRIML2,PPCDC,METTL8,POLE3,RAN,MPST,PTPRK,METTL1,CHD9,SLC3A2,RBCK1,GCNT2,ABCC4,SKIV2L2,HARS,KATNAL1,CDK4,MED27,HSPA5,TSN,GDPD1,COL4A3BP,ATG12,SUMO3,BRCA1,KCNH2,DLST,ODC1,LSG1,MGST1,KIF16B,PEX1,DYRK1B,GLS,LSS,HPRT1,MSRA,CHD3,EEFSEC,RAD51B,DPP4,ADAM9,PPP3CC,TSEN2,USP15,SEPHS2,XYLB,CTU2,OXNAD1,AOC3,TTN,SARS,PGPEP1,MCM6,CLK1,PRSS3,HSD17B10,FAN1,DNAH1,RNF40,TRMT13,ABCA5,PDE10A,PPIL2,GTF2H1,SYNJ2,PNPLA3,ALDH18A1,GMDS,CWF19L2,LRSAM1,NT5E,CAMKK2,WARS2,USP49,SETD2,OBSCN,METTL22,ACOXL,PGD,FAM135A,IRAK2,DNAH17,CASS4,DTD1,HMBS,GGT7,PTP4A2,BRSK2,DDX10,RNF114,USP7,MPI,NDUFA5,CYLD,SUCLG1,PAPD4,NDUFAF2,LPCAT2,PPP2R2A,RIPK1,RNF24,LPCAT3,DDX60L,KDM1A,METTL16,CAD,IDI1,DUS4L,UBR1,FGGY,ZDHHC6,IKBKB,HIBCH,MYH15,RNF2,AHCYL1,PRMT3,CASP10,PRPF19,SKIV2L,KDM3B,KAT8,DDX41,TUBA1A,NARS,THSD4,RAB7A,CPOX,AKAP13,CA5B,USP36,ATP5D,EXO1,RANBP2,RBBP8,ABHD3,ATG7,HSPB8,PUS1,MED20,SEPT5,EIF2B3,FAHD1,PPIL3,MUTYH,DMGDH,ESCO1,MINK1,AUH,HM13,MAP3K13,AGO2,MAP1S,VARS,APRT,CSNK1A1,PTPN2,ADH5,NDUFV1,CWC27,DDX31,POLR1B,CD44,PCK2,HSD17B12,PCSK6,ADAMTSL3,SMARCAD1,ABCF2,TEX14,TOP3A,DHX34,HIST1H4J,EXOG,RHOT2,PIK3CB,NEU1,POLR3A,SMPDL3B,POLR3G,ZRANB3,ADAT2,MSH3,FNTB,USP20,NDUFAF5,MYRF,RBPJ,TAF12,RPS6KC1,KIF1B,GCSH,CGN,MYCBP2,POLB,CUL4A,PRDX6,PRKAB2,DDX19A,ADAMTS6,GYG1,PRKCA,RAC3,UBR5,AARS,LPIN1,SUCLG2,RNF111,DPH6,ME1,CHD2,TRMT10A,FUT11,CSGALNACT2,ACADS,GDAP1,SETD1B,ALDH1L2,EYA3,TCEB3,DESI1,ZDHHC14,FOXRED1,DDX60,PLCXD2,DOT1L,GNAI1,DDAH2,TRRAP,HSDL2,SH3RF1,NSMCE1,CFD,XPNPEP1,DNAH2,NRP1,CCNB1IP1,TXN2,BLMH,PTPN14,DROSHA,LARS2,ST6GAL1,AK6,TATDN3,DPM3,TGFBR2,CHD5,NDUFS7,FKBP1A,PRKCE,HR,ENTPD5,PI4KB,USPL1,ATIC,PIGG,CNOT4,LPCAT1,PRPS1,FDFT1,ADARB1,SIK3,EXOSC2,DDX28,PRIM2,POLA1,AOC2,PCCA,RDH10,RAP1B,PTPN12,PLCB1,MTR,ARIH2,ATP9B,DAGLA,CAT,ASCC3,EPRS,MTHFD2,ALKBH3,NSF,D2HGDH,ZCCHC6,RIOK3,SQLE,DPEP1,UMPS,MACROD1,CNDP2,DHCR7,MAP2K4,SMYD3,HS2ST1,CPT1C,TRPM2,BIRC6,HFM1,UROD,NDUFB5,OLA1,KLHL18,POP5,PTPRG,RING1,PDE3A,FLAD1,CHD7,DECR1,ASNS,PUS3,SLX4,KDM2A,SHC1,PPID,UCHL5,GLYR1,LPIN2,TTC3,CMPK1,PNPLA4,KMT2A,ATP6AP1L,CDK12,RFC4,RFC3,PDK1,MTIF2,PCMT1,DLG4,GNL1,GALK2,MED16,MARCH6,SETD7,POLG2,STK10,DHX57,HSD3B7,SNCA,TAMM41,BAZ1A,CAMK2D,DCXR,G6PD,FTSJ1,LARGE,ACP1,TRMT2A,ALKBH1,TRAF3,MDN1,SETD6,XRCC4,MID1,VWA8,SSH2,BRAF,CA11,C10orf2,B4GALT5,MRI1,NFX1,FARS2,KIF5C,LIAS,MLH1,OPA1,GDPD5,INPP1,RPS6KA5,NEDD4,DCTPP1,ABL1,FTCDNL1,PMPCA,PHYKPL,HARS2,NLGN3,DYNC2H1,EXOSC4,MAP3K14,NT5M,CLK2,MBTPS2,PFKFB4,TTLL5,APEX1,PSAT1,WDFY3,AGPAT4,ADSL,TBRG4,APTX,PTK2,OASL,GUF1,MMAA,POLR2A,ECH1,KLHL22,FBXO21,RETSAT,ZDHHC11,DDX50,HELZ,RNF138,ATM,NDUFS5,PGAM5,ADK,STK4,KAT6A,IMMP2L,PIGM,MVK,KMT2E,ATRX,RARS2,PTPRA,KIF5A,CERS5,TRPM6,RCHY1,PLOD1,PPIL1,BCOR,SIRT2,STK33,AHCYL2,EDC3,PCYOX1L,RAP1A,KANSL1,LONRF2,ATG3,ANAPC11,MYH3,IPP,HYAL1,JOSD1,POLR3B,B3GNTL1,NDUFA6,SLC27A5,YARS,GALNT18,OGG1,LONP1,PRKACB,CARM1,TIMM50,SRPK2,TNK2,TRIM13,ITPA,SIRT6,LVRN,GPCPD1,MINA,KSR2,HDAC8,MTHFD1L,KMT2C,SGK2,ST3GAL5,RHOU,UBE3D,HLCS,TRMT5,CRCP,ABCC3,EME1,GALNT10,CLU,NOCT,LDAH,AK2,PIGN,CHST11,TAF1,PAX2,GPAT3,ALG8,PCSK7,C11orf54,PHGDH,RHBDD1,NAMPT,RNF141,P3H1,ISPD,N4BP2,POLR1E,ATP6V0D1,CPSF3L,HSD17B14,MTHFD1,PDE4A,TSTA3,PPAT,ELOVL6,JMJD1C,ELP3,TBXAS1,WBSCR22,LIG4,PSMA1,PRDM1,CORIN,DNAH14,UBE2E1,POP1,MGAT2,MYBBP1A,FDPS,HK2,RRAGA,PTRH2,CDKAL1,TRMT10B,TBCK,PDSS2,PDE9A,ASH1L,CEMIP,MYO7A,PIGH,SMARCA4,ARSJ,PUDP,DHX35,RIOK2,FARSA,LYPLAL1,CBR4,RPS6KL1,FHIT,ADCK4,MET,CPSF3,GNG5,HTRA2,TMLHE,ACSL5,MCEE,NARS2,PARP2,METTL2A,NLN,METTL15,DKC1,ATP8B2,EDEM2,UBR4,PUSL1,RAB10,TPK1,RAD54B,WARS,ZC3H12A,HYAL3,DUS3L,ALAD,COPS5,DUSP19,FKBP5,RNF130,USP11,ECHDC1,SMG1,YDJC,KLHL24,TNIK,BCKDK,SULT1C2,CAMK1,KLC4,NSUN6,PDE4B,TKFC,ATF7IP,ENOX1,PIP4K2A,GFM2,MAN1A1,PRKCH,GART,HAS3,KDELC1,SHMT2,FBL,ERI3,MICAL3,RPS6KB2,TOP1,MARCH9,KDM6B,KDM5B,GPHN,CRIM1,KDM5A,METTL23,SULT4A1,MARS,MEN1,PDE2A,PEAK1,EIF5B,NAPEPLD,TARS,HSPA1B,MFN2,ALG5,DAGLB,AGTPBP1,CUL2,PREPL,POLR1C,TATDN1,MMP16,ZAK,TRAPPC12,NIT1 |
| 2.388e-08 | -17.55 | mitochondrion | cellular component | GO:0005739 | 1621 | 279 | 17570 | 2233 |
AARS2,MRPL10,NT5C3A,PRKCA,COA1,ABHD6,AARS,LPIN1,CIAPIN1,NOS1AP,AMBRA1,ZFHX3,PMAIP1,ATP5G2,LETM2,EMC8,SUCLG2,ME1,LYRM5,FXN,PPM1K,ACADS,GDAP1,ALDH1L2,MSRB3,MCL1,HSH2D,FOXRED1,STOML2,PYCR1,DDX3X,DDAH2,HSDL2,BDH2,MPV17,FIS1,TXN2,SLC25A26,HERC2,TNNC1,LARS2,TATDN3,NDUFS7,YARS2,ANXA10,MTUS1,PRKCE,PI4KB,ATIC,MRPL21,COQ3,TOMM34,FADS1,TIMM8B,DDX28,BDNF,PCCA,IDH3G,CPT1A,LYRM7,CAT,MTHFD2,ALKBH3,TRAP1,D2HGDH,SURF1,GPN1,MACROD1,CPT1C,SDSL,PTCD2,DNM3,CCDC58,ATP6V1A,SUGCT,PDK4,NDUFB5,SLC25A44,NDUFB3,BLOC1S2,NUBPL,FLAD1,DECR1,SHC1,ABCA12,MRPS27,RMDN3,NT5C,SSBP1,MTHFD2L,PERP,CASP8AP2,GARS,LRRC75A-AS1,PDK1,SFXN4,MTIF2,POLG2,DHX57,SNCA,TAMM41,PEMT,DNAJA3,ALKBH1,RPS6KB1,TRAF3,VWA8,BRAF,C10orf2,TRAK1,FARS2,SLC25A12,LIAS,OPA1,NOL3,ABL1,PTRF,GATC,TRIAP1,PMPCA,PHYKPL,HARS2,NT5M,APEX1,CLYBL,TMEM126B,TMEM126A,LDHA,MRPS10,ADSL,TBRG4,GUF1,MMAA,ECH1,MRPL36,ANXA1,ETFDH,RARS,COQ9,ACOX1,SLC25A19,MYOM2,NDUFS5,PSAP,GPAM,PGAM5,UQCC1,CYP24A1,IMMP2L,LYRM4,LETM1,PPARGC1B,RARS2,SLC25A21,BCOR,COX10,MRPS30,TRMU,NDUFA6,SLC25A23,OGG1,LONP1,MPST,TIMM50,SESN2,HARS,HSPA5,NOL6,COL4A3BP,CAV1,MTHFD1L,SOX4,FLVCR1,DLST,MGST1,MPC1,TIMM44,GLS,MSRA,HLCS,TRMT5,EEFSEC,TNFRSF1A,CLU,UQCC2,DCAF5,MTCH1,CTU2,OXNAD1,SARS,AK2,FOXO1,HSD17B10,TIMM10,LYRM2,RHBDD1,ETFB,DDIT4,NDRG4,ALDH18A1,MTHFD1,NIPSNAP1,WARS2,BCS1L,CYB5B,C19orf70,HK2,SLC16A1,PTRH2,PFDN2,PDSS2,NDUFA5,SUCLG1,NDUFAF2,NTSR1,RIPK1,FAM210A,SLC9B2,GBF1,FDX1,MIEF1,NVL,FSIP2,CBR4,HIBCH,ADCK4,FHIT,TMEM14C,HTRA2,TMLHE,MCEE,NARS2,ACSL5,NARS,CPOX,MRRF,NLN,CA5B,TMEM186,ATP5D,RANBP2,TIMM17A,SLC25A11,PUS1,HEATR1,FAHD1,MUTYH,DMGDH,BCKDK,AUH,OXLD1,LETMD1,C14orf159,VARS,CHCHD10,GFM2,HDDC2,SLC25A20,MRPS11,ADH5,SACS,NDUFV1,SHMT2,PCK2,SLC25A1,ABCF2,RAP1GDS1,MARS,PALLD,EXOG,PDE2A,RHOT2,CHCHD6,MFN2,AGTPBP1,NDUFAF5,KIF1B,GCSH,NIT1 |
| 2.405e-08 | -17.54 | Helicase_C | pfam domains | PF00271 | 106 | 36 | 16629 | 2165 |
EP400,ATRX,DDX18,DDX19A,HFM1,SMARCA4,HLTF,CHD5,DHX35,DDX60L,CHD7,DDX56,DHX37,DHX33,DDX31,CHD2,SKIV2L,CHD9,DDX28,DDX41,DDX24,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,RAD54B,ZRANB3,DDX3X,ASCC3,SRCAP,DDX50,CHD3,DDX10 |
| 2.437e-08 | -17.53 | cervix-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-squamous_cell_carcinoma | 12377 | 1697 | 17775 | 2278 |
GGT1,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,SBF2,CCNL2,SLC6A8,ZNF44,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,LETM2,AP1M1,KDM5C,MSANTD2,SRRM2,ZNRD1,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,WDHD1,C5AR1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,LRRC40,SYNGR2,DIRAS1,RIOK1,RUNX1,VASH2,ZNF532,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,SAMD3,ANGPT2,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,IRS1,DYNC1H1,TSR1,KPNA1,NME7,RPL28,EHMT2,TRAP1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,RAB11FIP4,C16orf95,PAFAH1B1,C16orf45,DDR2,CD99L2,FAM122B,ST3GAL6,LCLAT1,CBWD5,MCM9,RPGRIP1L,CD96,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,MGLL,ZC3H3,LYST,PMS1,KMT2D,ZNF480,PI4KAP2,SLCO6A1,FAM171A2,PCNXL2,MEF2D,KCNH3,GSTCD,SLC35D1,DSP,VPS53,MAT2A,SLC39A14,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,ARL13B,POLR3E,CAMKMT,HOXA3,CENPBD1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,POLR3D,TAF3,CFDP1,UNC13A,ANXA5,LTN1,RAPGEFL1,ACTR3B,C15orf41,SAMD4A,PNMA1,SPTAN1,VPS37A,DDX24,ZC3H18,NXN,RSBN1,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,SRD5A3,BMP4,SORCS2,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,ANKRD11,HKR1,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,FMNL3,ATF4,MIOS,PPARG,CDK4,ANK2,TSN,SUMO3,PSMG1,LAMA2,KCNH2,CRYBG3,LSG1,C1orf122,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,MAPK8IP3,FAN1,ZIC2,ARID1B,SPIRE1,MLX,ZNF358,CEP290,VPS72,NDRG4,VAPB,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,CYB5B,TCF7L2,PRPF40B,GRIK4,CASS4,SIL1,DTD1,GGT7,SH3PXD2A,USP7,SART1,ID1,OLFM2,PAPD4,SUCLG1,UPK3B,ARID2,OSBPL9,SLC2A1,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,URB1,PLXNB1,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,KIRREL2,RAB7A,VIM,NHSL1,EIF3H,ZNF251,EXO1,IFT81,LMBR1L,ATG7,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,FNTB,USP20,RBM26,ZNF32,RBPJ,NR2F2,XPO6,KIF1B,C6orf223,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,OSBP2,C2orf76,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,PLCXD2,GNAI1,SPOP,OSBPL1A,DOT1L,TRRAP,LSM14A,SH3RF1,CCNT1,HSPBAP1,ARL6IP5,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,SPOCK3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,SSR4,C1orf50,NDUFS7,MTUS1,TECTA,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,CAV2,FDFT1,IFNGR2,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,SLC26A11,MTR,ZNF850,ATP9B,CAT,ASCC3,C6orf141,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,NCOR1,CNDP2,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,PTPRG,CORO6,PABPC1L,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,ERC1,SERP1,HSD3B7,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,MBTD1,LARGE,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,DNAJC22,OPA1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,GUF1,SLC23A2,ZFP62,RETSAT,DDX50,ZNF155,IREB2,COQ9,ATM,SVIL,APAF1,ADK,IPO4,IMMP2L,PIGM,ZNF76,LETM1,EIF3C,ATRX,RARS2,SLC52A3,PCYOX1L,DST,CNIH3,JAZF1,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ARRDC3,TFPI,VWCE,MINA,KSR2,PITPNB,MTHFD1L,KMT2C,ST3GAL5,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,SCART1,ZCCHC8,UBXN1,PCSK7,SMG7,QSER1,EVPL,TIMM10,RNF141,ELL,ISPD,CCDC124,PRF1,ATP6V0D1,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,PFDN2,TBL1X,IFITM2,FNBP1L,TBCK,PDE9A,N4BP2L2,NR2C2AP,DMXL2,TCF12,PSTPIP2,TMEM183A,TNXB,SMARCA4,TBCCD1,COBLL1,TMEM177,SPATS2,ARSJ,PIBF1,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,NVL,PPFIBP1,SNTG2,ITGAX,VCL,TMEM120B,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,METTL2A,GRHL3,ATXN1,DKC1,EDEM2,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,DUS3L,HNRNPR,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,TMEM101,RNF130,BRD9,SMG1,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,STC2,TMEM99,LDLRAD3,ERI3,PKNOX1,MICAL3,RPS6KB2,MARCH9,KDM6B,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,WDR35,AGTPBP1,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,TOM1L1,PCDH7,SREBF2,NEK6,NSRP1,RASSF3,FAAH2,RABGAP1L,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,PACRGL,RFX2,AKAP12,MSRB3,PLEKHM3,MCL1,DCUN1D5,TMSB4X,DDX3X,BRCA2,ZNF266,SUPT4H1,MEF2C,HERC2,CARS,EP400,TRIP6,SIRT7,PRAF2,NHS,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,SERBP1,HMGCR,FADS1,GTF2H3,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,GTF2A1,CLASRP,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,PDK4,MYH9,AGAP6,NECAP1,SAFB2,EEA1,STAM,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ZKSCAN1,FMNL1,ATRIP,NT5C,GSTA4,CEP63,MTHFD2L,PERP,GARS,KRT7,FAM111B,ARHGEF10,ADAM32,ATP6V0A1,TTC28,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,PEMT,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,C1orf226,SF3A3,WDR37,JMJD6,AKT1S1,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,ERICH1,POLK,FRA10AC1,FAM126B,ZNF467,DDX49,FOXC1,RPA1,KISS1R,ETFDH,TRIB3,BAZ2B,PXDN,POLE2,PLPPR2,SLCO5A1,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,KDM4C,ANAPC4,SRM,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,MFGE8,HECTD3,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,PPCDC,UBAP2L,ZNF85,RAN,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,FLNC,METTL1,CHD9,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,SKIV2L2,ZNF414,KATNAL1,COL4A3BP,NOL6,ATG12,BRCA1,ZNF91,FLVCR1,CCDC28B,PEX1,KIF16B,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,XYLB,SEPHS2,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,HOMER2,BCS1L,RNH1,MEX3B,ZNFX1,SUPT5H,NR2F1,VAC14,PGD,PWP1,SPAG9,ITPRIPL1,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,TESC,PRKAR2A,RNF114,KCTD7,LPCAT2,RBFOX2,GPR143,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,UBR1,FSIP2,DNAJB6,ARMC5,ZDHHC6,HIRIP3,ZFP37,ETF1,HIBCH,ANO8,CORO1A,AKNAD1,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,THSD4,TMEM123,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,ABHD3,ITGA2,ZNF436,TSSC1,NFASC,ZNF18,PPIL3,PKIB,ATXN7L2,UNC13D,MAP3K13,FAM46B,MAP1S,C14orf159,ARFIP2,ZNF346,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,HIST2H3D,PRICKLE2,GREB1,CD44,PCK2,FBXO31,HSD17B12,GINS3,ADAMTSL3,TEX14,DHX34,PEAR1,RAP1GDS1,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,POLR3G,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,SET,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRDX6,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RPS16,VPS52,RNF111,ME1,PRADC1,CEP135,MEIS3,TBC1D8,DPF3,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,SEMA3F,MAK16,SH3GL1,SKIL,HSDL2,ZNF81,VPS13D,GREB1L,DNAH2,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ASAP1,SLC16A9,SAMD13,IGF2BP1,LPCAT1,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,PTPN12,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,SRRD,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,UMPS,IQSEC2,MAP2K4,ZFHX2,RTTN,PTCD2,TBKBP1,AMOTL1,TRPM2,CCDC58,LIN28B,SPATA2L,ZBTB37,URB2,HFM1,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,PDE3A,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,KDM2A,UCHL5,GLYR1,VGF,NBEA,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,HTR7,YIPF2,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,MRI1,TCF3,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,IKBKAP,GDPD5,REEP5,TMCO6,NEDD4,ZNF483,RGS17,PTRF,NISCH,TRIAP1,PMPCA,HARS2,UPF2,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,FAM120B,TSHZ1,WDFY3,C19orf43,FZD3,KCNMA1,WDR18,OASL,MMAA,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,MYOM2,BRWD3,SLC43A1,LRRC41,SLC37A3,MVK,PHF3,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,SNAPC4,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,THADA,YLPM1,LONRF2,ATG3,ZNHIT6,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,SLC27A5,NDUFA6,TRIM14,LONP1,LAMA4,ZBTB17,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,LVRN,GPCPD1,HDAC8,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,ZNF397,TNRC6A,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,ALG8,MED13L,XPO7,C11orf54,ETFB,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,NRIP1,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,SLC9B2,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CCDC50,CAMTA2,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,HN1,TMLHE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAD54B,WARS,ZC3H12A,ADNP,COPS5,DISP1,SCARB1,HEATR1,USP11,TSPAN5,TNIK,SH2D3A,C17orf80,DBF4,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,MFSD10,SFI1,MAN1A1,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,SHMT2,TTC17,AMOT,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,TARS,MFN2,RERE,ZNF708,MPP7,ZNF330,CUL2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,HRH1 |
| 2.697e-08 | -17.43 | Helicase_C | interpro domains | IPR001650 | 108 | 36 | 18293 | 2341 |
EP400,ATRX,DDX18,HFM1,DDX19A,SMARCA4,HLTF,DHX35,CHD5,DDX60L,CHD7,DDX56,DHX37,DHX33,CHD2,DDX31,SKIV2L,CHD9,DDX28,DDX24,DDX41,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,RAD54B,ZRANB3,DDX3X,SRCAP,ASCC3,DDX50,CHD3,DDX10 |
| 2.768e-08 | -17.40 | GTGACGY_V$E4F1_Q6 | MSigDB lists | GTGACGY_V$E4F1_Q6 | 623 | 128 | 17758 | 2279 |
PTP4A1,POLB,NF1,HMOX2,SYNJ1,UBR5,PCDH7,DST,THADA,LETM2,XRCC2,RELB,JOSD1,PRKACB,DPF3,NR6A1,SKIV2L2,ANK2,MTHFD1L,FOXRED1,DLST,SLC9A5,C1orf122,MLLT10,CXADR,DDX3X,BRCA2,CCNT1,PER1,XPNPEP1,RIOK1,PRPF4,DMTF1,DCTN3,IFT57,EGR1,ANKRD17,RHOBTB1,SSR4,RLF,CHD5,PITPNM1,RNF40,RNF141,MCAM,ATP6V0D1,TERF2,STAG1,TLE3,IDH3G,BCS1L,ATAT1,ASCC3,GTF2A1,TRAP1,ZZEF1,HK2,PTRH2,PURB,UMPS,SENP3,HMBS,PFDN2,GGT7,PRKAR2A,ID1,PAFAH1B1,ATP6V1A,SPATA2L,PPP2R2A,ISG20L2,LCLAT1,FDX1,RING1,KDM2A,IKBKB,GLYR1,SLC38A2,INTS12,IPO11,CTC1,RFC4,STAMBP,TFCP2,RAB7A,MRRF,GNL1,MARCH6,GALK2,GSTCD,ERC1,UBR4,DNTTIP1,RANBP2,RBBP8,ADNP,HOXA3,ZBTB11,NOLC1,ANKS1A,PKIB,BRAF,HM13,MINK1,DNAJA4,MAP3K13,DBF4,RCAN1,MYNN,TGFB2,BHLHE40,GIGYF2,MBNL1,FAM50A,NDUFV1,ANXA7,DSG2,ACTR3B,SULT4A1,TEX14,NOP58,CTIF,RERE,DDX50,VPS37B,KIF1B,C6orf223,NIT1 |
| 2.814e-08 | -17.39 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 16526 | 2177 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,APRT,RBM19,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,TMEM139,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 2.859e-08 | -17.37 | PUJANA_CHEK2_PCC_NETWORK | MSigDB lists | PUJANA_CHEK2_PCC_NETWORK | 754 | 149 | 17758 | 2279 |
GNB3,CUL4A,NF1,CSNK2A1,TTI1,NUP160,SMARCB1,SRSF2,ANAPC10,UBAP2L,ME1,POLE3,RAN,KIAA0922,FXN,OGG1,TRIP13,TMPO,RBCK1,ZNF195,KLHL23,CDK4,ATG12,WDHD1,BRCA1,MCM2,DLST,ODC1,MAK16,CHAF1A,SLC7A1,HPRT1,BRCA2,INSIG1,XPNPEP1,PRPF4,BLMH,MCM6,KHDRBS1,PAX2,SMG7,RNFT2,EIF2S2,ATIC,COPS3,MCM5,MYC,TIMELESS,MED24,CTR9,AGL,PRPS1,PABPC1,SERBP1,HMGCR,FDFT1,FADS1,KRT20,RB1CC1,POLA1,PSMA1,TTYH2,ARID1A,CPT1A,UBE2E1,PWP1,TSR1,MTHFD2,SYNCRIP,FDPS,HK2,GPN1,SQLE,SLC16A1,KIAA0196,DDX10,ZBTB24,HS2ST1,DDX18,URB2,SMARCA4,ISG20L2,SSBP2,POP5,PELP1,NDUFB3,NOP56,CAD,IDI1,MPHOSPH10,PPID,RNF2,SSBP1,PRMT3,PRPF19,RFC4,RFC3,PARP2,NPM3,PCMT1,TMEM123,PNN,DKC1,EIF3H,MAT2A,EXO1,BAZ1A,TAF2,RBBP8,SMARCC1,ADNP,HNRNPR,TIMM17A,CEBPZ,FTSJ1,MED20,NOLC1,DNAJC2,TCF3,DBF4,RNASEH2B,POM121,PTPN2,NOP16,TRIAP1,PMPCA,SHMT2,LARP4B,FBL,HNRNPM,TOP1,PSMC3IP,LDHA,ADSL,EXOG,EIF5B,RPA1,POLR3G,OXSR1,TOE1,POLE2,ZNF330,ORC5,TAF4,SET,ATM,EIF2S1,NCBP2,GCSH |
| 2.889e-08 | -17.36 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 16536 | 2178 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,APRT,RBM19,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,TMEM139,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 3.082e-08 | -17.30 | MODULE_17 | MSigDB lists | MODULE_17 | 356 | 83 | 17758 | 2279 |
TCF12,PPP2R2A,CSNK2A1,SMARCA4,SLC29A1,RAC3,CAD,DECR1,ASNS,SRSF2,MRPS27,AP1M1,SSBP1,POLE3,KDM5C,SERPINH1,AHCYL1,SRRM2,TRIP13,SF3A1,PRPF19,RFC4,PRAME,RBCK1,SKIV2L2,PSMG1,MARCH6,HIST1H2BL,MCM2,CHAF1A,PYCR1,PES1,HPRT1,INSIG1,LSM14A,COPS5,ARL4A,H2AFX,HIC2,NOLC1,BLMH,TMEM158,AK2,MCM6,ST6GAL1,PRSS3,UBXN1,ALG8,HSD17B10,SF3A3,ZIC2,APRT,PHLDA2,DDIT4,IGF2BP3,SNW1,GART,COPS3,MYC,SEC24C,ATIC,SHMT2,LPCAT1,MYB,FDFT1,MTHFD1,HMGCR,FADS1,APEX1,PTPN12,RANGAP1,BMS1,CYB5B,ABCF1,ISG15,ANXA1,RARS,GADD45A,FDPS,SQLE,IGBP1,DDIT3,SLC43A1 |
| 3.123e-08 | -17.28 | cytoplasmic part | cellular component | GO:0044444 | 7817 | 1113 | 17570 | 2233 |
PTP4A1,ARHGAP26,ADAM19,DPH1,ACTG1,DCP1B,AARS2,MRPL10,MKS1,TUBE1,SBF2,HMOX2,ABHD6,LPAR3,CIAPIN1,PDZD2,ZFHX3,ATP5G2,LETM2,AP1M1,EMC8,MAD1L1,PPM1K,EIF4E3,NRAS,UPP1,EXOC6B,AP4B1,KIF15,C5AR1,SHISA5,PYCR1,AHNAK,RBSN,SYNGR2,BDH2,MPV17,TPM1,SLC25A26,EPM2AIP1,TRIO,PIK3R4,PARN,PITPNM1,CHN1,CNST,APLF,GEMIN4,MRPL21,PABPC1,PPA1,MYB,RABEPK,ZNF675,ALG6,WDR61,STAG1,IDH3G,ATAT1,USP10,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,RDH11,IRS1,DYNC1H1,KPNA1,GSTO2,RPL28,TRAP1,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,SGSM3,GALE,SDSL,RAB11FIP4,PAFAH1B1,SUGCT,VTI1A,GRINA,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,NDUFB3,SPG21,CLCN6,MMP14,MGLL,DENND1A,LYST,LRRC75A-AS1,EIF3J,SLC35D1,NUDT15,VPS53,MAT2A,FBXL5,SLC39A14,ARHGAP21,MISP,ASTN2,ARL13B,POLR3E,CAMKMT,RPS6KB1,CEP170,RAB30,BAG1,MAPT,MORC2,SHQ1,ATG2B,GAS6,TRIM22,PSMF1,POLR3D,ACOT11,ANXA5,PTGS1,RPL22L1,SPTAN1,VPS37A,LDHA,NXN,CCDC113,PPIP5K2,UBC,ANXA1,MRPL36,SRCAP,HERC1,ACOX1,SRD5A3,UQCC1,MTMR1,CYP24A1,CUL7,SLC25A21,FAM13A,MAP2K3,AMPD3,COPS4,NCKIPSD,ZMYM2,SLC25A23,DBN1,FMNL3,RBCK1,MIOS,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,KRTCAP2,KCNH2,ODC1,DLST,LSG1,CXADR,BSN,LSS,HPRT1,INSIG1,AHNAK2,DPP4,PPP3CC,UQCC2,CTU2,FOXO1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,LYRM2,SPIRE1,CEP290,NDRG4,VAPB,PNPLA3,NIPSNAP1,WARS2,OBSCN,METTL22,CYB5B,ACOXL,TBC1D2,SNX24,SIL1,PTP4A2,USP7,SART1,MPI,ID1,SUCLG1,PAPD4,SLC48A1,NDUFAF2,OSBPL9,NTSR1,SLC2A1,RPS29,RIPK1,TNKS1BP1,PPP1R9A,FDX1,ANKRD13A,IDI1,NUP133,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,ARHGAP17,RAB7A,VIM,CA5B,EIF3H,TJAP1,ATG7,HSPB8,EIF2B3,FAHD1,MUTYH,PARD3,DMGDH,MINK1,HM13,AUH,AGO2,APRT,VARS,SLC25A20,ADH5,TTC1,PCSK6,AP4S1,ABCF2,SLC35G1,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,DKK1,CACNB1,DSC2,BCAS3,FNTB,USP20,KIF1B,PRKCSH,GYG1,PRKCA,LPIN1,EXOC1,ZFYVE28,SUCLG2,DPH6,SPAG6,CSGALNACT2,ACADS,GDAP1,VSNL1,EFHC1,ZDHHC14,CLNS1A,OSBPL1A,GNAI1,GZF1,DDAH2,TRRAP,LSM14A,SH3RF1,ARL6IP5,CFD,NRP1,BLMH,JUP,CDC42EP2,LARS2,ST6GAL1,TATDN3,DPM3,CRACR2A,SSR4,NDUFS7,MTUS1,SLC7A11,MYC,PIGG,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,PCCA,RDH10,RAPGEF4,RAP1GAP2,RAP1B,MTR,SLC26A11,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SRP68,SQLE,CNDP2,DHCR7,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,FLNB,BLOC1S2,NUBPL,DECR1,ASNS,LPIN2,DTNBP1,MRPS27,TTC3,RMDN3,CMPK1,CASP8AP2,PCMT1,PREX1,MARCH6,ERC1,SERP1,HSD3B7,SNCA,CAMK2D,DCXR,G6PD,LARGE,IFT140,TRAF3,TBXA2R,XRCC4,MID1,VWA8,NOSTRIN,BRAF,B4GALT5,FARS2,OPA1,INPP1,ABL1,NEBL,S100A14,DYNC2H1,ERRFI1,SLC40A1,PXN,APEX1,PSAT1,ZFYVE1,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,GUF1,INF2,RETSAT,COQ9,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,KAT6A,IMMP2L,PIGM,LETM1,LYRM4,EIF3C,RARS2,SLC30A7,PCYOX1L,DST,CNIH3,ANAPC11,SLC39A7,MYH3,KIAA0922,SLC35C2,YARS,CARM1,CEP128,TNK2,SESN2,SKAP2,ITPA,TFPI,ARRDC3,MINA,TMEM216,MTHFD1L,PITPNB,SGK2,ST3GAL5,MPC1,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,CRCP,CLU,DCAF5,MTCH1,DCTN3,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,SMG7,TIMM10,NAMPT,P3H1,PRF1,ATP6V0D1,AKAP11,MTHFD1,HSD17B14,HBG2,PPAT,ELOVL6,XPO5,EIF2A,SYT1,HERPUD1,UBE2E1,EXOC6,MGAT2,BICD1,FSCN1,FAT1,FDPS,CDKAL1,TMEM117,SLC16A1,PFDN2,FNBP1L,PDE9A,AGO3,DMXL2,SNX27,CHMP2A,PSTPIP2,CEMIP,PIGH,ARSJ,PIBF1,SOCS1,NVL,CBR4,FHIT,ADCK4,VCL,C6orf89,AUP1,NARS2,ANTXR2,MRRF,POU2F1,EDEM2,S100A16,ARMC4,ALAD,DUS3L,KPNA3,ARNTL,WDR73,FKBP5,ARC,SMG1,TMCC1,TMEM33,DNAJC2,BCKDK,DYM,PDE4B,VPS45,IGF2BP2,CHCHD10,PIP4K2A,GFM2,PEX7,SEC24C,DCTN4,STC2,TOP1,MARCH9,PPP1R9B,DNMBP,SULT4A1,PDE2A,EIF5B,TMEM187,CTIF,SERINC1,DAGLB,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,NIT1,TRAPPC12,CHAC1,NT5C3A,SYNJ1,NUP160,COA1,NOS1AP,AMBRA1,PABPC4,TOM1L1,SREBF2,NEK6,PMAIP1,SYN2,RABGAP1L,PDS5B,ZNF148,LYRM5,HRG,FXN,CDK6,WLS,PTPRM,MSRB3,AKAP12,MCL1,TMSB4X,SLC50A1,STOML2,DDX3X,BRCA2,FIS1,RBP1,TNNC1,HERC2,CARS,PRAF2,PLA2G12A,CLINT1,YARS2,SLC39A11,ABCA7,SH2B3,EIF2S2,ALKBH8,PRMT5,CALN1,COQ3,AGL,MAP3K12,FMNL2,TOMM34,EMC10,SERBP1,HMGCR,FADS1,PEA15,BDNF,TIMM8B,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,EIF4A2,RYR2,IMPDH2,CPT1A,EVI5,ABCF1,NCDN,SURF1,GPN1,CNOT6,COG5,SPRED2,DNM3,ABCA3,MAP2K5,BTBD2,ATP6V1A,NPAS2,ACTR3,PDK4,MYH9,NECAP1,STAM,HSPA1A,EEA1,TMEM150C,ABCA12,FMNL1,PYCRL,GSTA4,NT5C,CEP63,MTHFD2L,PERP,MALL,GARS,STAMBP,ARHGEF10,ATP6V0A1,FKBP3,FGFR1,PDE8B,HLA-DMA,CDC16,PEMT,WDR7,FUS,TRIM36,SERINC5,INSIG2,TRAK1,ID2,AKT1S1,TGFB2,BHLHE40,MBNL1,POM121,GATC,ARHGAP1,DIS3L2,ULBP1,NUDC,CEP83,CLYBL,CEP295,ARHGAP39,MRPS10,PDE3B,TRIB3,RARS,ETFDH,PXDN,STX1A,SLC25A19,PSAP,GPAM,IGBP1,DOCK6,ANAPC4,SRM,BCAS4,PPARGC1B,HECTD3,CSNK2A1,RNF43,TMEM132A,COX10,SEC16A,BIRC2,ABL2,ARHGAP18,PHKA1,MARVELD2,TRMU,PPCDC,RAN,MPST,CDC37,METTL1,FLNC,GCNT2,SLC3A2,ABCC4,HARS,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,MGST1,KIF16B,PEX1,GLS,ZNF622,MSRA,EEFSEC,CCDC146,TNFRSF1A,C2CD5,CHMP4C,XYLB,AOC3,OXNAD1,TTN,SARS,PGPEP1,STX8,HSD17B10,MEX3A,ZFP36L1,DNAH1,RNF40,ABCA5,PDE10A,PPIL2,SYNJ2,ALDH18A1,NAA38,TRAPPC9,PAXBP1,BCS1L,MEX3B,TRAPPC6B,VAC14,PGD,PWP1,SPAG9,SYNCRIP,SNAP23,IRAK2,DNAH17,PPP1R12B,ARHGAP12,HMBS,BRSK2,NAPA,PRKAR2A,KCTD7,NDUFA5,CYLD,LPCAT2,GPR143,PPP2R2A,LPCAT3,RNF24,CAD,DUS4L,UBR1,DNAJB6,FSIP2,ZDHHC6,IKBKB,ETF1,HIBCH,CORO1A,PRMT3,CASP10,SKIV2L,SEC24A,EVL,TUBA1A,DDX41,NARS,CPOX,C1QTNF1,AKAP13,NUP214,TMEM186,PUM3,ATP5D,SMAD3,RANBP2,SLC30A3,SIX5,TIMM17A,CLEC16A,PUS1,SEPT5,AP2S1,UNC13D,MAP3K13,C14orf159,MAP1S,ARFIP2,CSNK1A1,IQGAP2,PTPN2,SACS,NDUFV1,ANXA7,IFIT5,DDX31,PCK2,CD44,HSD17B12,TPM4,RAP1GDS1,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,NEU1,CENPP,POLR3G,TPD52L2,GPC2,SET,GLG1,EIF2S1,NDUFAF5,MYRF,RPS6KC1,GCSH,PRDX6,PRKAB2,TMEM109,ENAH,IKBIP,RAC3,AARS,GIPR,RPS16,VPS52,ME1,CEP135,FUT11,SEH1L,DDN,ATG9A,ALDH1L2,CUX1,HSH2D,FOXRED1,SH3GL1,SKIL,HSDL2,DNAH2,TXN2,IFT57,CCDC53,OPHN1,CCDC47,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,ENTPD5,PI4KB,ASAP1,ATIC,IGF2BP1,LPCAT1,PRPS1,TERF2,USE1,DDX28,SYNGAP1,SIGMAR1,PTPN12,RABAC1,PLCB1,LYRM7,EPRS,KIDINS220,SERF2,NSF,UBAP1,PMEPA1,D2HGDH,UMPS,PEX13,MACROD1,IQSEC2,MAP2K4,PTCD2,AMOTL1,CCDC58,NDUFB5,AP1B1,SLC25A44,PDE3A,FLAD1,TMEM184A,SHC1,UCHL5,VGF,GLYR1,NBEA,SSBP1,SERPINH1,NAA35,CFAP221,PDK1,SFXN4,MTIF2,WDPCP,DLG4,POLG2,DHX57,CPED1,TAMM41,YIPF2,DNAJA3,ALKBH1,ANXA2,PDCD11,SCAMP3,C10orf2,MRI1,SLC25A12,RTN4,MON2,LIAS,NOL3,GDPD5,FOXO3,NEDD4,DCTPP1,COMMD9,PTRF,NISCH,TRIAP1,PMPCA,RDX,UPF2,HARS2,PHYKPL,NLGN3,EXOSC4,MAP3K14,LARP4B,YBX3,NT5M,MBTPS2,PFKFB4,WDFY3,KCNMA1,TBRG4,PTK2,OASL,MMAA,ECH1,YIF1A,COL26A1,ZDHHC11,STX18,MYOM2,PGAM5,RABEP1,STK4,MVK,NF1,KIF5A,CERS5,PLOD1,SIRT2,BCOR,STK33,AHCYL2,EDC3,MRPS30,SRPRB,RTN1,ANAPC1,RAP1A,ATG3,ANAPC10,HYAL1,RELB,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,PRKACB,TIMM50,TRIM13,TXLNG,GPCPD1,HDAC8,CAV1,SOX4,TCTN1,GEMIN5,RHOU,EPN2,SUFU,TRMT5,DNAJC1,PQBP1,BBIP1,GALNT10,NOCT,TNRC6A,LDAH,CHST11,PIGN,AK2,FN1,SEC24D,PAX2,GPAT3,ALG8,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,ATXN2,BANF1,GLTP,VOPP1,PDE4A,TBXAS1,PSMA1,WWC1,BLOC1S4,C19orf70,ISG15,SDCCAG8,EXOC4,HK2,RRAGA,PTRH2,PDSS2,ASH1L,PCNT,MYO7A,FAM210A,SLC9B2,GBF1,SLC39A1,MIEF1,VPS18,FARSA,LYPLAL1,RPS6KL1,TMEM14C,HTRA2,TMLHE,MOSPD1,MCEE,ACSL5,PHLDB2,FAM172A,COL5A2,NLN,TOR1AIP2,ATP8B2,RAB10,WARS,TPK1,PLIN2,HYAL3,COPS5,SLC25A11,SRFBP1,SCARB1,HEATR1,ECHDC1,TNIK,DNAJA4,SULT1C2,OXLD1,TKFC,LETMD1,PPHLN1,CLSTN2,MFSD10,HDDC2,SFI1,MRPS11,MAN1A1,PRKCH,GART,TANK,KDELC1,SHMT2,UTS2,AMOT,SLC25A1,MARS,ARHGAP32,MEN1,TARS,HSPA1B,MFN2,ALG5,CUL2,NCBP2,PREPL,MMP16 |
| 3.346e-08 | -17.21 | MARTINEZ_RESPONSE_TO_TRABECTEDIN | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN | 49 | 22 | 17758 | 2279 |
TCF12,HMGA2,NCOR2,ID1,CRADD,PPARG,POLA1,PCCA,CUX1,PTPRG,SMAD3,IRS1,BRE,ZFHX3,HERC1,ME1,DDX10,XRCC4,ADK,SRPK2,LPP,PTPRK |
| 3.433e-08 | -17.19 | ion binding | molecular function | GO:0043167 | 5991 | 900 | 16491 | 2164 |
ARHGAP26,ADAM19,ACTG1,AARS2,NAT10,CACNA1H,TUBE1,SBF2,HLTF,NT5C3A,ZNF44,HMOX2,LPAR3,CIAPIN1,PCDH7,SKI,ZNF37A,MMP7,NEK6,IKZF5,ZFHX3,SYN2,THAP4,PDS5B,WIZ,ZNF148,KDM5C,HRG,ZNRD1,FXN,CDK6,PPM1K,NRAS,LIMA1,GNL3,EHMT1,KIF15,MSRB3,PLEKHM3,ABCC2,MCM2,ZNF197,STOML2,DDX3X,ZNF266,RBSN,SUPT4H1,RAD18,RIOK1,DIRAS1,RUNX1,ZNF532,LPP,CARS,ADGRE2,HERC2,TNNC1,EP400,TRIP6,SLK,TRIO,SIRT7,PIK3R4,PLA2G12A,RSF1,PARN,SLC1A1,PITPNM1,YARS2,ABCA7,SH2B3,RSPRY1,CHN1,RBM20,DDX56,UBE3A,EIF2S2,DHX37,APLF,MCM5,ALKBH8,ZNF326,CALN1,ZNF518B,MAP3K12,PPA1,ANGPT2,HMGCR,ZNF675,GATAD2B,GTF2H3,TIMM8B,MYO10,ZNF587,PRDM16,EPS15L1,EIF4A2,IDH3G,TYW1,ZNF512B,RYR2,IMPDH2,MBNL2,TRIM37,ABCF1,ZNF655,DYNC1H1,LRP1B,NME7,PDLIM1,EHMT2,TRAP1,FGFBP1,CDK9,ZNF160,GPN1,ADGRE5,CNOT6,BPNT1,PDLIM5,SDSL,DNM3,RAB11FIP4,MAP2K5,ABCA3,ZNF516,TRERF1,DDX18,GTF2H2C,PAFAH1B1,ATP6V1A,NPAS2,PDK4,ACTR3,DDR2,MYH9,AGAP6,TUBB6,ZMAT2,EEA1,CBWD5,MCM9,HSPA1A,ZBED2,PRKD3,ZSWIM7,ABCA12,ERI1,ZKSCAN1,CLCN6,MMP14,INTS12,NT5C,MSH4,PEG10,PXK,ZC3H3,LYST,PMS1,KMT2D,GARS,STAMBP,ZNF480,ADAM32,NUDT15,MAT2A,FGFR1,PDE8B,TAF2,FBXL5,ZFAND3,KDM4B,NSMCE2,PEMT,HIPK2,ARL13B,PAM,RPS6KB1,FUS,BRCC3,ZBTB11,RAB30,MORC2,TRIM36,ZNF786,SESTD1,SF3A3,JMJD6,GAS6,TRIM22,IP6K2,ZNF691,MBNL1,TTLL11,CBWD6,GATC,SUV39H2,TAF3,ACAP3,UNC13A,ANXA5,LTN1,PTGS1,ZNF710,FBXL19,ACTR3B,DIS3L2,SPTAN1,DDHD1,FGF9,DDX24,CLYBL,POLK,ZC4H2,ZC3H18,PPIP5K2,ZNF467,UBE2K,PDE3B,DDX49,ANXA1,RPA1,OXSR1,TRIB3,TOE1,ETFDH,NSD1,RARS,SRCAP,BAZ2B,PXDN,ACOX1,BMP4,KDM4C,CYP24A1,TRIM16,POLR1A,MFGE8,CSNK2A1,RNF43,BIRC2,GIT2,FRRS1,MAP2K3,ABL2,AMPD3,DHX33,TRMU,XRCC2,HKR1,ZNF85,RAN,ZNF3,ZMYM2,SLC25A23,DSC3,CHD9,RBCK1,ZNF124,SLC3A2,AEBP2,ABCC4,SKIV2L2,PPARG,HARS,BAZ2A,ZNF414,CDK4,KATNAL1,ATOX1,HSPA5,GDPD1,COL4A3BP,BRCA1,ZNF91,LSG1,MGST1,MLLT10,PEX1,KIF16B,BSN,DYRK1B,HPRT1,ZNF622,CHD3,EEFSEC,ARL4A,RAD51B,ADAM9,PPP3CC,MAGI1,RNF214,C2CD5,SEPHS2,XYLB,SARS,TTN,AOC3,MCM6,CLK1,PRSS3,NKD2,MEX3A,SMAD7,FAN1,ZFP36L1,TRIM15,ZIC2,RLF,DNAH1,RNF40,RNFT2,ZNF358,ABCA5,TRMT13,PDE10A,ALDH18A1,GMDS,LRSAM1,SNX29,NT5E,WARS2,CAMKK2,USP49,BCS1L,OBSCN,MEX3B,ZNFX1,CYB5B,ACOXL,NR2F1,DNAH17,IRAK2,SNX24,ZNF430,DTD1,HMBS,DDX10,SH3PXD2A,BRSK2,TESC,PRKAR2A,RNF114,MPI,CYLD,PAPD4,SUCLG1,ARID2,LPCAT2,RPS29,GPR143,RIPK1,ZNF83,RNF24,ZNF709,DDX60L,RPAIN,ZNF121,FDX1,KDM1A,CAD,ZNF608,ZBTB21,IDI1,JAG1,DUS4L,UBR1,IKBKB,ZDHHC6,CYB5D1,MYH15,RNF2,ZFP37,PRMT3,SKIV2L,SOBP,SEC24A,KAT8,KDM3B,PCGF3,TUBA1A,AKAP8L,DDX41,NARS,RAB7A,AKAP13,CA5B,ARL5B,ZNF251,ATP5D,EXO1,SMAD3,RANBP2,ZNF333,KLF4,ITGA2,ZNF436,ZNF18,SEPT5,FAHD1,MUTYH,ZNF589,PARD3,ZNF507,ESCO1,MINK1,MCM10,MAP3K13,AGO2,ARFIP2,APRT,VARS,ZNF346,CSNK1A1,FOXP1,POGZ,ZNF594,IQGAP2,ADH5,NDUFV1,ANXA7,ZNF561,PRICKLE2,DDX31,POLR1B,PCK2,HSD17B12,PCSK6,ADAMTSL3,SMARCAD1,ZNF654,ABCF2,ZMYM5,TPM4,TEX14,DHX34,TOP3A,FERMT2,EXOG,GPNMB,RHOT2,PIK3CB,POLR3A,ZRANB3,CDH24,GPC2,DSC2,ZBTB8OS,ADAT2,MSH3,FNTB,USP20,RBM26,ZNF32,NR2F2,RPS6KC1,KIF1B,ZNF292,POLB,MYCBP2,PRKCSH,DDX19A,ADAMTS6,GYG1,PRKCA,NBEAL1,RAC3,AARS,UBR5,EXOC1,S100A10,ZFYVE28,SUCLG2,RNF111,ME1,CHD2,DPH6,CSGALNACT2,ZNF646,ACADS,DPF3,NR6A1,EYA3,VSNL1,EFHC1,ZDHHC14,DDX60,OSBPL1A,GNAI1,GZF1,DDAH2,SH3RF1,NSMCE1,ZNF81,HIC2,XPNPEP1,DNAH2,CCNB1IP1,NRP1,BMI1,SPOCK2,ZNF598,SPOCK3,ZMAT3,DROSHA,EGR1,CELSR1,LARS2,ZHX3,AK6,OPHN1,TATDN3,CRACR2A,CCDC47,TGFBR2,PDCD5,CHD5,NDUFS7,ANXA10,PRKCE,HR,PI4KB,ZNF586,ASAP1,CNOT4,LPCAT1,PRPS1,SCAF11,ADARB1,SIK3,DDX28,RREB1,PRIM2,PCCA,AOC2,POLA1,RAPGEF4,RAP1B,PLCB1,MTR,ZNF850,ARIH2,PHF6,ATP9B,ZNF425,CAT,DAGLA,ASCC3,EPRS,MTHFD2,ALKBH3,NSF,VCAN,ZZEF1,ZBTB12,D2HGDH,RIOK3,ZCCHC6,SQLE,DPEP1,CNDP2,SMYD3,MAP2K4,ZFHX2,ZNF254,SYT17,LIN28B,ZBTB37,HFM1,UROD,KIAA0232,OLA1,RING1,TRIM66,PDE3A,PHC2,CHD7,NUBPL,FLAD1,DECR1,ZNF827,ASNS,SHC1,KDM2A,NBEA,TTC3,CMPK1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,ZCCHC14,PDK1,MTIF2,PREX1,GNL1,GALK2,MARCH6,STK10,DHX57,SNCA,ZBTB25,VDR,BAZ1A,CAMK2D,DNAJA3,ZNF236,MBTD1,LARGE,ALKBH1,CBWD1,TRAF3,MDN1,ANXA2,NOLC1,TROVE2,MID1,VWA8,FGFBP3,BRAF,B4GALT5,C10orf2,ZNF280C,NFX1,FARS2,SLC25A12,KIF5C,MYNN,MLH1,LIAS,OPA1,NOL3,RPS6KA5,INPP1,NEDD4,DCTPP1,ZNF239,ABL1,ZNF483,FTCDNL1,NISCH,PMPCA,PHYKPL,HARS2,S100A14,DYNC2H1,MAP3K14,NT5M,MBTPS2,NAV3,CLK2,PFKFB4,TSHZ1,PXN,TTLL5,APEX1,WDFY3,ZFYVE1,KCNMA1,BMS1,PTK2,APTX,OASL,KLF6,GUF1,MMAA,POLR2A,ZFP62,DDX50,ZDHHC11,ZNF155,IREB2,HELZ,ORC5,RNF138,ATM,APAF1,ADK,KAT6A,STK4,ZNF76,LETM1,MVK,PHF3,ATRX,NF1,KMT2E,RARS2,KIF5A,TRPM6,RCHY1,PLOD1,ZNF107,SIRT2,STK33,CUTC,DST,SRPRB,ZNF804A,RAP1A,LONRF2,ZNHIT6,JAZF1,ANAPC11,MYH3,ZEB1,POLR3B,PCOLCE2,SLC27A5,GALNT18,YARS,LONP1,TRIP13,PRKACB,TRIM14,ELOF1,SRPK2,ZBTB17,DEAF1,TNK2,DTNB,TRIM13,ZNF195,SIRT6,ZNF680,ITPA,LVRN,VWCE,MINA,KSR2,HDAC8,MTHFD1L,SGK2,ZSCAN2,KMT2C,CDHR3,TIMM44,RHOU,GATA6,HLCS,ZGRF1,ABCC3,GALNT10,EME1,ZC3H8,ZNF397,NOCT,AK2,FN1,ZCCHC8,RHOBTB1,SEC24D,TAF1,STXBP6,DPF2,C11orf54,TIMM10,RNF141,P3H1,ZNF354A,PRF1,ZCCHC7,N4BP2,MTHFD1,ZNF629,ZNF234,HBG2,PDE4A,PPAT,JMJD1C,ELP3,ZBED4,TBXAS1,ZFP14,LIG4,PRDM1,SYT1,AGAP1,DNAH14,UBE2E1,ATAD5,FAT1,FDPS,RRAGA,HK2,CDKAL1,ZFP90,TBCK,PDE9A,ZBTB24,ZNF706,SNX27,CHMP2A,DLL4,ASH1L,CELSR3,MYO7A,TNXB,SMARCA4,ARSJ,PUDP,DHX35,GBF1,ZSCAN5A,MIEF1,ZC3H13,RIOK2,VPS18,FARSA,NVL,CBR4,RPS6KL1,ZNF142,ITGAX,CPSF3,MET,ZNF460,TMLHE,MCEE,NARS2,ACSL5,ANTXR2,COL5A2,NLN,ATP8B2,EDEM2,UBR4,RAB10,S100A16,WARS,TPK1,RAD54B,ZC3H12A,ALAD,IKZF4,DUS3L,ADNP,COPS5,ZNF557,SCARB1,RNF130,SMG1,YDJC,BCKDK,TNIK,DNAJA4,ARL15,CAMK1,PDE4B,DBF4,TKFC,CLSTN2,PIP4K2A,GFM2,MFHAS1,MAN1A1,PRKCH,GART,SEC24C,TANK,DSG2,SHMT2,ERI3,DMRT1,MICAL3,RPS6KB2,MARCH9,KDM6B,GPHN,KDM5B,FGF2,ZNF821,KDM5A,ANKMY2,ASAP3,ZNF324B,MARS,ARHGAP32,PDE2A,EIF5B,ZNF407,PEAK1,NAPEPLD,TARS,MFN2,RERE,ZNF221,HSPA1B,ZNF708,DAGLB,WDR35,ZNF330,AGTPBP1,ZRANB2,TATDN1,ZAK,MMP16,ZSWIM6,HRH1 |
| 3.454e-08 | -17.18 | haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_neoplasm | 11621 | 1603 | 17775 | 2278 |
ARHGAP26,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,CIAPIN1,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,AP1M1,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,CCDC57,NRAS,RNMT,KLHL23,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,WDHD1,ABCC2,ZNF197,AHNAK,RAD18,LRRC40,SYNGR2,BDH2,MPV17,RIOK1,RUNX1,TPM1,VASH2,SLC25A26,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,PITPNM1,CHN1,RBM20,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,GSTO2,NME7,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,RAB11FIP4,GTF2H2C,C16orf95,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,RPGRIP1L,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,MSH4,MGLL,TRMT12,ZC3H3,DENND1A,LYST,KMT2D,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,CEP170,CATSPERG,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,TRIM22,PSMF1,TTLL11,TAF3,CFDP1,UNC13A,ACOT11,LTN1,RAPGEFL1,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,VPS37A,DDX24,LSM12,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,OXSR1,NSD1,SRCAP,HERC1,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,SLC25A21,FAM13A,SCAF8,FRRS1,MAP2K3,AMPD3,SRSF2,PHF5A,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,PPARG,CDK4,ANK2,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,BSN,DYRK1B,TCF7L1,INSIG1,CHD3,E2F4,AHNAK2,DPP4,ADAM9,PRPF4,TSEN2,MAGI1,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ARID1B,RNFT2,MLX,CEP290,MBD2,VPS72,NDRG4,CTR9,PNPLA3,LRSAM1,CWF19L2,SNX29,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,PTP4A2,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,OLFM2,PAPD4,SUCLG1,ARID2,NDUFAF2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,PAG1,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,NRF1,IDI1,JAG1,NUP133,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,ARHGAP17,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,CA5B,NHSL1,TJAP1,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,FAHD1,MUTYH,PARD3,DMGDH,ESCO1,VARS,RBM19,FOXP1,POGZ,SLC25A20,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,SMARCAD1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,SMPDL3B,POLR3A,DKK1,CDH24,NOL10,DSC2,L3MBTL3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,XPO6,KIF1B,C6orf223,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,SH3RF1,CCNT1,NSMCE1,ARL6IP5,LUC7L3,HIC2,NRP1,WDR66,BLMH,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,TATDN3,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,PABPC1L,FLNB,IGSF1,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,MRPS27,DTNBP1,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,SATB2,MARCH6,MEGF11,SETD7,ERC1,SERP1,BAZ1A,MSX2,CAMK2D,SMARCC1,G6PD,MBTD1,LARGE,IFT140,SLC4A7,CBWD1,XRCC4,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,RCAN1,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,DYNC2H1,CELF1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,PACS1,BMS1,KLF6,GUF1,SLC23A2,RETSAT,DDX50,ZNF155,IREB2,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,IMMP2L,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,SLC30A7,DST,CNIH3,JAZF1,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,HCFC2,YARS,CEP128,SRPK2,DTNB,DEAF1,TNK2,SESN2,SKAP2,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,PITPNB,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,EME1,ZC3H8,DCAF5,MTCH1,RHOBTB1,ZCCHC8,STXBP6,PCSK7,SMG7,QSER1,EVPL,ELL,ZNF354A,WDR27,ISPD,CCDC124,PRF1,ZCCHC7,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,TBL1X,TBCK,PDE9A,N4BP2L2,DMXL2,TCF12,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,C6orf89,MAML3,NARS2,ANTXR2,PRAME,METTL2A,GRHL3,ATXN1,METTL15,EDEM2,UBR4,S100A16,BATF3,ARMC4,IKZF4,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,TMEM101,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,TMCC1,BCKDK,SUPT6H,CAMK1,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,SEMA3E,SOGA1,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,STC2,DCTN4,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,WDR35,VPS37B,ANKRD30BL,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RABGAP1L,RASSF3,FAAH2,PDS5B,ZNF148,LYRM5,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,RFX2,AKAP12,PLEKHM3,DCUN1D5,C10orf76,RBM28,STOML2,DLEU1,DDX3X,BRCA2,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,ABCA7,SLC39A11,SH2B3,DDX56,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,CALN1,COQ3,AGL,MAP3K12,ZNF518B,FMNL2,SERBP1,FADS1,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,PRKD3,ABCA12,ERI1,ZKSCAN1,PYCRL,ATRIP,GSTA4,CEP63,TMEM136,LSM10,GARS,KRT7,FAM111B,ARHGEF10,ADAM32,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,ZNF786,XPC,SESTD1,TRAK1,ID2,SF3A3,WDR37,AKT1S1,RSRC1,MBNL1,POM121,KRI1,TADA3,TMSB10,ARHGAP1,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,FAM98A,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,SLCO5A1,PTPN4,SLC25A19,PSAP,GPAM,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,TMEM132A,SEC16A,COX10,GIT2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,UBAP2L,RAN,ETV1,SF3A1,PTPRK,CDC37,FLNC,CHD9,GCNT2,ABCC4,HARS,BAZ2A,SKIV2L2,KATNAL1,GDPD1,MED27,COL4A3BP,NOL6,ATG12,BRCA1,ZNF91,FLVCR1,MGST1,KIF16B,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,OXNAD1,MCM6,STX8,LRRC28,TRIM15,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,SYNJ2,GMDS,ALDH18A1,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,ATXN7,ITPRIPL1,FAM135A,SYNCRIP,PALB2,DNAH17,TBPL1,PPP1R12B,NAPA,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RSL1D1,LPCAT3,ZNF83,PELP1,KDM1A,CAD,DUS4L,UBR1,FSIP2,DNAJB6,IKBKB,C15orf40,CYB5D1,HIRIP3,ETF1,HIBCH,ANO8,ZFP37,CORO1A,AKNAD1,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,SLC35F2,AKAP13,ENC1,NUP214,USP36,BTBD11,SMAD3,RANBP2,SLC30A3,ZNF333,TIMM17A,CLEC16A,ITGA2,ZNF436,TSSC1,NFASC,ZNF18,PUS1,ZNF589,AP2S1,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,ARFIP2,C14orf159,CSNK1A1,C15orf57,ZNF594,IQGAP2,PTPN2,NDUFV1,SACS,ZNF561,CWC27,HIST2H3D,PRICKLE2,GREB1,SELT,CD44,PCK2,HSD17B12,ADAMTSL3,ZNF654,ZMYM5,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,GPNMB,CHCHD6,TMEM175,PIK3CB,ARMC3,MKX,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ADAT2,GLG1,MSH3,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,CGN,PRDX6,PRKAB2,PLRG1,ENAH,IKBIP,RAC3,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,ME1,CEP135,MEIS3,SEH1L,TBC1D8,DDN,DPF3,SLC38A6,SETD1B,NR6A1,ALDH1L2,NOL8,CUX1,SEMA3F,SAP30BP,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,USE1,SCAF11,SIK3,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,RTTN,PPDPF,PTCD2,TBKBP1,AMOTL1,TRPM2,SPATA2L,URB2,RIBC2,HFM1,OLA1,KLHL18,SPATS2L,AP1B1,TRIM66,PDE3A,PHC2,CHD7,ZNF827,PUS3,SHC1,KDM2A,NBEA,SSBP1,KMT2A,PLEKHA4,NAA35,ZCCHC14,RFC4,RFC3,MPP6,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,TBC1D16,STK10,DHX57,DCBLD2,HTR7,DNAJA3,ZNF236,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,NCOR2,UTP14A,TTC27,C10orf2,ZNF280C,NFX1,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,NEDD4,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,PMPCA,HARS2,UPF2,RDX,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,MMAA,NOP58,ECH1,YIF1A,FBXO21,ZDHHC11,HELZ,STX18,MYOM2,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,SLC37A3,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,ZNF107,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,RTN1,ZNF804A,ANAPC1,YLPM1,THADA,LONRF2,ZNHIT6,ANAPC10,RELB,JOSD1,POLR3B,SLC27A5,NDUFA6,OGG1,PRKACB,TRIP13,LONP1,ZBTB17,LAMA4,TXLNG,ZNF680,SLC38A1,CMIP,LVRN,GPCPD1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,RHOU,GEMIN5,PAF1,TMEM132B,GATA6,SUFU,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,C11orf54,RHBDD1,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,CCDC112,NRIP1,N4BP2,CPSF3L,VOPP1,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,KIAA1328,TMEM182,PDSS2,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,ZSCAN5A,FARSA,BRE,LYPLAL1,CCDC50,CAMTA2,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,PARP2,NLN,R3HDM1,ATP8B2,C1orf174,RAB10,TPK1,RAD54B,WARS,ZC3H12A,ADNP,SLC25A11,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,NBR2,SULT1C2,SH2D3A,DBF4,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,HDDC2,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,KDELC1,SHMT2,TTC17,UTS2,AMOT,DMRT1,PAQR6,MSX1,TEAD1,ANKMY2,PPP1R21,PHACTR2,ARHGAP32,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,MBD6,PREPL,TATDN1,MMP16,ZAK,SLC16A10 |
| 3.598e-08 | -17.14 | pleura | COSMIC cancer mutations | pleura | 5040 | 756 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,HLTF,SLC6A8,NUP160,SYNJ1,AMBRA1,NOS1AP,SKI,PCDH7,PDZD2,MMP7,IKZF5,NEK6,PMAIP1,THAP4,FAAH2,RABGAP1L,RASSF3,MAD1L1,KDM5C,FXN,AVEN,SRRM2,CDK6,NRAS,KLHL23,PTPRM,C11orf80,AKAP12,MCL1,MCM2,ZNF197,DDX3X,AHNAK,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,P2RY11,MEF2C,CARS,BANP,HERC2,TMEM63C,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,ABCA7,CHN1,SH2B3,DDX56,UBE3A,DHX37,SLC38A5,MCM5,ANP32B,GEMIN4,CALN1,MAP3K12,MYB,HMGCR,PEA15,ZNF675,GTF2H3,STAG1,RB1CC1,PRDM16,EIF4A2,RYR2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,NCDN,IRS1,DYNC1H1,LRP1B,KPNA1,EHMT2,TRAP1,SURF1,GPN1,ARHGAP10,COG5,SPRED2,DNM3,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,CLCN6,MMP14,MSH4,TRMT12,DENND1A,PMS1,KMT2D,STAMBP,FAM111B,ARHGEF10,ADAM32,ATP6V0A1,MEF2D,FKBP3,FGFR1,GNG2,TAF2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,HIPK2,RPS6KB1,FUS,BRCC3,ZBTB11,LAMA5,BAG1,MAPT,RAB30,TRIM36,HMGA2,XPC,SESTD1,ID2,GAS6,IP6K2,POM121,TADA3,SNW1,SUV39H2,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,ARHGAP39,LDHA,RSBN1,IL6R,FOXC1,DDX49,ANXA1,RPA1,OXSR1,TRIB3,NSD1,POLE2,HERC1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,WDR13,HECTD3,CSNK2A1,TMEM132A,SEC16A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,PHKA1,DHX33,MARVELD2,XRCC2,NCKIPSD,ANKRD11,ZNF85,RAN,POLE3,ZMYM2,ETV1,FAM184A,PTPRK,VPS13B,FMNL3,CHD9,CDK4,HSPA5,TSN,GMFB,COL4A3BP,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,BSN,DYRK1B,HPRT1,TP53BP1,CHD3,ARL4A,E2F4,PER1,TECPR2,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,NKD2,SMAD7,LAMTOR3,MEX3A,MAPK8IP3,HSD17B10,HES6,TRIM15,ARID1B,RNF40,ZNF358,CEP290,PDE10A,MBD2,GTF2H1,VAPB,SYNJ2,WNT16,SNX29,TRAPPC9,CAMKK2,CRADD,SETD2,OBSCN,MEX3B,ZNFX1,NR2F1,VAC14,PRPF40B,SPAG9,SYNCRIP,PALB2,SNX24,PPP1R12B,CASS4,ARHGAP12,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,USP7,SART1,ID1,SUCLG1,ARID2,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,PPP1R9A,SEMA6A,DDX60L,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,CORO1A,AKNAD1,IPO11,CASP10,KDM3B,SKIV2L,ARHGAP17,PCGF3,AKAP8L,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,AUH,MAP3K13,APRT,FOXP1,CSNK1A1,ZNF594,PTPN2,ADH5,FAM50A,SACS,SURF2,DDX31,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,TPM4,TEX14,TOP3A,DHX34,PEAR1,RAP1GDS1,ARHGEF12,PALLD,PIK3CB,POLR3A,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,KIF1B,MYCBP2,POLB,CGN,CUL4A,PRKAB2,TNFRSF21,ENAH,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,LPIN1,MGA,ZFYVE28,SUCLG2,CHD2,FAM127A,SETD1B,NOL8,GNG7,ZDHHC14,DENND4A,PLCXD2,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,DDAH2,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,IFT57,DROSHA,JUP,EGR1,ANKRD17,ST6GAL1,CENPB,OPHN1,SSR4,TGFBR2,PDCD5,CHD5,PRKCE,FKBP1A,NAV1,HR,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,SAMD13,IGF2BP1,PRPS1,TERF2,SIK3,DDX28,RREB1,PRIM2,ANAPC13,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,RABAC1,ARID1A,PLCB1,EHBP1,MTR,PHF6,CAT,HIF1A,PMEPA1,VCAN,SPEN,RIOK3,UMPS,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,RTTN,BIRC6,PTPRG,IGSF1,RING1,PHC2,NUBPL,TERF2IP,SLX4,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,NAA35,SAP30,RFC4,BRD4,RFC3,PDK1,PREX1,SATB2,MED16,TBC1D16,POLG2,STK10,ERC1,DHX57,BAZ1A,CAMK2D,SMARCC1,DNAJA3,G6PD,FTSJ1,H2AFX,ACP1,ALKBH1,TRAF3,MDN1,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,DNAJC22,NOL3,IKBKAP,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,NEBL,RDX,COPS7B,NLGN3,S100A14,CLK2,NAV3,PXN,APEX1,FZD3,ADSL,BMS1,FBXO21,IREB2,HELZ,ORC5,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,PIGM,PHF3,NF1,ATRX,PTPRA,FANCD2,TRPM6,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,DST,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,MYH3,ANAPC10,RELB,KIAA0922,YARS,OGG1,TRIM14,CARM1,PRKACB,SRPK2,LAMA4,TNK2,SESN2,TRIM13,FBXW4,TXLNG,CMIP,SIRT6,VWCE,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,SOX4,SERGEF,TAF9B,CHAF1A,CCDC3,GEMIN5,RHOU,HLCS,SUFU,DNAJC1,PQBP1,CTAGE5,CSMD3,ASB3,EME1,CLU,ZC3H8,COPS6,DCAF5,MTCH1,FBXO45,AK2,PIGN,RHOBTB1,TAF1,PCSK7,MED13L,SMG7,XPO7,ETFB,DDIT4,RNF141,ELL,SEMA3D,AKAP11,N4BP2,MSI2,RANBP6,XPO5,JMJD1C,LIG4,WWC1,PRDM1,SYT1,UBE2E1,MYBBP1A,HK2,TBL1X,TBCK,FNBP1L,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,PBX1,SPATS2,ST7L,PIBF1,DHX35,RIOK2,BRE,SOCS1,NVL,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,MET,ITGAX,CPSF3,GNG5,AUP1,MOSPD1,TMLHE,PARP2,METTL2A,ATXN1,DKC1,UBR4,RAB10,TPK1,RAD54B,IKZF4,KPNA3,ADNP,COPS5,DUSP19,FKBP5,DISP1,SCARB1,RNF130,USP11,SMG1,TMCC1,DNAJC2,TNIK,BCKDK,DNAJA4,SH2D3A,CAMK1,DYM,DBF4,MED18,ATF7IP,IGF2BP2,PPP1R1C,FAM49A,PIP4K2A,MAN1A1,PRKCH,CTNNBL1,SEC24C,TANK,AMOT,RPS6KB2,TOP1,KDM6B,ARNTL2,DNMBP,IL11RA,GPHN,FGF2,KDM5A,SCFD2,MARS,ARHGAP32,PDE2A,TMEM187,NAPEPLD,GADD45A,CUL2,NFKBIB,MMP16,ZAK |
| 3.688e-08 | -17.12 | Cytosolic tRNA aminoacylation | REACTOME pathways | R-HSA-379716 | 24 | 15 | 8202 | 1117 |
CARS,FARSA,RARS,EPRS,SARS,GARS,NARS,HARS,MARS,VARS,YARS,AARS,PPA1,TARS,WARS |
| 3.694e-08 | -17.11 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1493 | 266 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,HLTF,PRKCA,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,KIF15,ABCC2,MCM2,DDX60,DDX3X,DNAH2,RIOK1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,RAPGEF4,IDH3G,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,MAP2K4,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,PDK4,ACTR3,OLA1,DDR2,MYH9,CBWD5,HSPA1A,MCM9,PDE3A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,GALK2,STK10,DHX57,FGFR1,MAT2A,CAMK2D,HIPK2,DNAJA3,CBWD1,RPS6KB1,MDN1,NOLC1,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,RPS6KA5,TTLL11,ABL1,GATC,CBWD6,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,KIF5A,RARS2,TRPM6,CSNK2A1,STK33,MAP2K3,ABL2,DHX33,XRCC2,TRMU,MYH3,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,TIMM44,PEX1,KIF16B,DYRK1B,HLCS,CHD3,RAD51B,ABCC3,MAGI1,XYLB,SEPHS2,TTN,SARS,AK2,MCM6,TAF1,CLK1,DNAH1,ABCA5,PDE10A,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,PDE4A,BCS1L,OBSCN,LIG4,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,HK2,BRSK2,TBCK,DDX10,PRKAR2A,PAPD4,MYO7A,RIPK1,SMARCA4,DDX60L,DHX35,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,ACSL5,NARS2,SKIV2L,DDX41,NARS,ATP8B2,TPK1,RAD54B,WARS,ATP5D,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,PDE4B,TKFC,VARS,APRT,CSNK1A1,PIP4K2A,PRKCH,GART,DDX31,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,PDE2A,PEAK1,PIK3CB,TARS,HSPA1B,ZRANB3,MSH3,RPS6KC1,ZAK,KIF1B |
| 4.025e-08 | -17.03 | adenyl nucleotide binding | molecular function | GO:0030554 | 1501 | 267 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,HLTF,PRKCA,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,KIF15,ABCC2,MCM2,DDX60,DDX3X,DNAH2,RIOK1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,RAPGEF4,IDH3G,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,MAP2K4,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,CBWD5,HSPA1A,MCM9,PDE3A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,GALK2,STK10,DHX57,FGFR1,MAT2A,CAMK2D,HIPK2,DNAJA3,CBWD1,RPS6KB1,MDN1,NOLC1,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,RPS6KA5,TTLL11,ABL1,GATC,CBWD6,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,KIF5A,RARS2,TRPM6,CSNK2A1,STK33,MAP2K3,ABL2,DHX33,XRCC2,TRMU,MYH3,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,TIMM44,KIF16B,PEX1,DYRK1B,HLCS,CHD3,RAD51B,ABCC3,MAGI1,XYLB,SEPHS2,TTN,SARS,AK2,MCM6,TAF1,CLK1,DNAH1,ABCA5,PDE10A,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,PDE4A,BCS1L,OBSCN,LIG4,UBE2E1,DNAH14,ATAD5,IRAK2,DNAH17,HK2,SIL1,BRSK2,TBCK,DDX10,PRKAR2A,PAPD4,MYO7A,RIPK1,SMARCA4,DDX60L,DHX35,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,ACSL5,NARS2,SKIV2L,DDX41,NARS,ATP8B2,RAD54B,TPK1,WARS,ATP5D,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,PDE4B,TKFC,VARS,APRT,CSNK1A1,PIP4K2A,PRKCH,GART,DDX31,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,PDE2A,PEAK1,PIK3CB,TARS,HSPA1B,ZRANB3,MSH3,RPS6KC1,ZAK,KIF1B |
| 4.152e-08 | -17.00 | lung-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-adenocarcinoma | 15921 | 2111 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SGSM3,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,MBD2,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,NEBL,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC30A7,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,CYLD,GPR143,RSL1D1,RNF24,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,MMAA,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,ETFB,DDIT4,CEP164,ATXN2,GLTP,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,MAN1A1,PRKCH,GART,TANK,KDELC1,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,VPS37A,LSM12,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,CNOT4,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,ZFYVE1,GUF1,SLC23A2,RETSAT,ZNF155,COQ9,ORC5,SVIL,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,METTL23,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,GARS,FAM111B,NPM3,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,DIS3L2,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PUS1,AP2S1,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,DAGLA,KIDINS220,SERF2,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 4.152e-08 | -17.00 | intestinal_adenocarcinoma | COSMIC cancer mutations | intestinal_adenocarcinoma | 7530 | 1084 | 17775 | 2278 |
ARHGAP26,CDCP1,THOC5,DPH1,CNTNAP3,AARS2,NAT10,TUBE1,SBF2,CCNL2,ABHD6,LPAR3,PDZD2,IKZF5,ZFHX3,AP1M1,MAD1L1,KDM5C,SRRM2,PPM1K,CCDC57,NRAS,KLHL23,RNMT,LIMA1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,SLC9A5,AHNAK,LRRC40,DIRAS1,VASH2,ZNF532,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,MED24,WDR60,GEMIN4,CCDC88C,PABPC1,SAMD3,NOM1,KLRD1,GATAD2B,ZNF675,STAG1,KCNQ3,ARID5B,ATAT1,USP10,ARRDC4,IRS1,DYNC1H1,TSR1,PDLIM1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,RAB11FIP4,C16orf95,PAFAH1B1,DDR2,NUP43,ST3GAL6,RPGRIP1L,TBC1D22A,SETD5,INTS12,PEG10,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,PCNXL2,KCNH3,DSP,VPS53,ZFAND3,ARHGAP21,KDM4B,ASTN2,NSMCE2,ARL13B,HOXA3,CEP170,METTL2B,CATSPERG,BAG1,MAPT,RAB30,XRRA1,ATG2B,RNASEH2B,ZNF691,TAF3,UNC13A,ACOT11,RAPGEFL1,ZNF710,RPL22L1,SPTAN1,TTPAL,DDX24,ZC3H18,RSBN1,PPIP5K2,UBC,CCDC150,NSD1,SRCAP,HERC1,ACOX1,SORCS2,MTMR1,CYP24A1,RBM33,FAM13A,NLE1,FRRS1,SRSF2,COPS4,NCKIPSD,ANKRD11,METTL8,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,PPARG,ANK2,HSPA5,TSN,LAMA2,KCNH2,ODC1,LSG1,BSN,TCF7L1,CHD3,AHNAK2,TSEN2,MAGI1,PRSS3,SMAD7,FAN1,ARID1B,SPIRE1,CEP290,NDRG4,CTR9,PNPLA3,LRSAM1,CWF19L2,SETD2,OBSCN,METTL22,ACOXL,TCF7L2,GRIK4,TTC38,CASS4,GGT7,DDX10,SH3PXD2A,SART1,OLFM2,PAPD4,SUCLG1,ARID2,SLC2A1,RIPK1,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,ZNF121,DDX60L,URB1,PLXNB1,ZNF608,NRF1,JAG1,NUP133,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,SOBP,TLCD1,ARHGAP17,AKAP8L,KIRREL2,ANKRD33B,NHSL1,TJAP1,EXO1,LMBR1L,KLF4,INTS9,EIF2B3,MUTYH,PARD3,ZNF507,ESCO1,VARS,RBM19,POGZ,SLC25A20,TTC1,CPNE7,C12orf4,LRRIQ1,MON1A,SMARCAD1,PLAC8L1,TOP3A,FERMT2,RANGAP1,PALLD,SMPDL3B,POLR3A,CDH24,NOL10,DSC2,L3MBTL3,TAF4,CSRNP1,FNTB,USP20,RBM26,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCA,NBEAL1,EXOC1,ZFYVE28,CHD2,ZNF646,ACADS,OSBP2,EFHC1,CAMSAP2,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,GZF1,DOT1L,OSBPL1A,TRRAP,SH3RF1,CCNT1,LUC7L3,HSPBAP1,HIC2,WDR66,BMI1,SPOCK3,NMD3,CDC42EP2,JUP,PRPF31,ST6GAL1,DLGAP4,MTUS1,TECTA,HR,SLC7A11,SCAF1,MYC,RTFDC1,EXOSC2,RREB1,PRIM2,IFNGR2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,ANGPTL4,MTR,PHF6,ATP9B,ASCC3,ALKBH3,VCAN,SPEN,MED15,BIVM,ZCCHC6,NCOR1,CNDP2,SMYD3,CPT1C,VMA21,BIRC6,TMEM104,PTPRG,PABPC1L,FLNB,RING1,NOP56,NUBPL,ASNS,SOCS6,SHF,TTC3,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,ZBTB25,MSX2,DNTTIP1,SMARCC1,MBTD1,LARGE,IFT140,TRAF3,MID1,SSH2,NOSTRIN,BRAF,KIF5C,OPA1,GIGYF2,ABL1,NEBL,ERRFI1,NAV3,TMC7,FER1L5,TTLL5,PXN,PSAT1,ZFYVE1,AGPAT4,PACS1,BMS1,SLC23A2,ZFP62,INF2,IREB2,ORC5,ATM,SVIL,APAF1,PIGM,ZNF76,ATRX,RARS2,SLC52A3,SLC30A7,DST,MYH3,ZEB1,KIAA0922,HCFC2,CEP128,SRPK2,DTNB,TNK2,DEAF1,SIRT6,ARRDC3,TFPI,MINA,KSR2,MTHFD1L,SGK2,KMT2C,TIMM44,CCDC3,TMCO1,EIF4ENIF1,CC2D1B,FAM114A2,CSMD3,ASB3,CLU,DCAF5,MTCH1,VTA1,PCSK7,SMG7,EVPL,NAMPT,RNF141,HVCN1,ZNF354A,PRF1,ZCCHC7,LRP3,AKAP11,ZNF629,MTHFD1,XPO5,ZBED4,JMJD1C,LIG4,CORIN,SYT1,AGAP1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,DMXL2,PSTPIP2,SMARCA4,TBCCD1,COBLL1,SPATS2,ARSJ,PIBF1,RIOK2,ZC3H13,RAET1E,NVL,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,MAML3,NPW,ANTXR2,GRHL3,POU2F1,DKC1,UBR4,ARMC4,HNRNPR,ZNF557,CEBPZ,RNF130,ARC,NFRKB,BRD9,SMG1,TMCC1,SUPT6H,PDE4B,ATF7IP,SEMA3E,SOGA1,ENOX1,GFM2,BMP6,STC2,RPS6KB2,TOP1,KDM6B,SLC6A16,ARNTL2,DNMBP,CRIM1,KDM5A,SCFD2,EIF5B,NAALADL2,CTIF,ZNF221,WDR35,AGTPBP1,ZSWIM6,CACNA1H,CSPP1,SYNJ1,AMBRA1,PABPC4,PCDH7,TOM1L1,NSRP1,RASSF3,PDS5B,FNIP2,ZNF148,HRG,CDK6,GNL3,PTPRM,PACRGL,RFX2,AKAP12,DCUN1D5,C10orf76,DDX3X,ZNF266,BRCA2,HERC2,CARS,EP400,KHDRBS1,SIRT7,RSF1,KCNJ14,ABCA7,KIAA1671,MCM5,CACNB2,NOC3L,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,COQ3,FMNL2,HMGCR,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,ZNF512B,RYR2,ONECUT2,ABCF1,VPS13C,LRP1B,CLASRP,LEMD3,ZNF160,MB21D2,COG5,SPRED2,ZNF516,DNM3,ABCA3,TRERF1,DDX18,BTBD2,NPAS2,PDK4,MYH9,NECAP1,SAFB2,PRKD3,ABCA12,FMNL1,PYCRL,CEP63,LSM10,FAM111B,ARHGEF10,ADAM32,TTC28,FGFR1,PDE8B,TAF2,CDC16,PEMT,HIPK2,PAM,WDR7,BRCC3,ZBTB11,YEATS2,LAMA5,ANKS1A,LRCH1,TRIM36,SESTD1,TRAK1,TGFB2,MBNL1,RSRC1,PVRL3,ACAP3,HNRNPM,SOX6,DIS3L2,FAM98A,ERICH1,ARHGAP39,R3HDM2,FAM126B,ZNF467,PDE3B,DDX49,CASC1,RPA1,RARS,TRIB3,ETFDH,BAZ2B,PXDN,POLE2,ARID3B,PLPPR2,STX1A,PTPN4,SLC25A19,SLCO5A1,GPAM,DOCK6,KDM4C,ANAPC4,CORO2B,FAM227A,POLR1A,PPARGC1B,MFGE8,CSNK2A1,RNF43,TMEM132A,TTI1,SEC16A,ABL2,DHX33,MARVELD2,TRMU,ZNF85,ETV1,SF3A1,PTPRK,FLNC,CHD9,SLC3A2,ABCC4,SKIV2L2,BAZ2A,MED27,NOL6,BRCA1,KIF16B,MSRA,TP53BP1,PER1,EEFSEC,CCDC146,TECPR2,SOCS4,TNFRSF1A,SGSM2,RNF214,XYLB,OXNAD1,AOC3,SARS,ITPRIP,RLF,DNAH1,KIAA1958,PDE10A,PPIL2,TIMELESS,GTF2H1,SYNJ2,GMDS,NT5E,CAMKK2,TRAPPC9,TLE3,HOMER2,ZNFX1,SUPT5H,VAC14,PWP1,ATXN7,SPAG9,FAM135A,PALB2,SYNCRIP,DNAH17,NAPA,TESC,LPCAT2,GPR143,ZNF83,RNF24,CAD,FSIP2,ARMC5,C15orf40,HIRIP3,ANO8,ZFP37,CORO1A,CASP10,TMEM200A,KAT8,SKIV2L,PCGF3,EVL,THSD4,SLC35F2,TMEM123,AKAP13,ENC1,ARL5B,NUP214,USP36,BTBD11,SMAD3,RANBP2,SLC30A3,RBBP8,CLEC16A,ZNF333,ITGA2,TSSC1,PRRT3,PUS1,NFASC,AP2S1,ATXN7L2,UNC13D,MAP1S,C14orf159,RMI1,ZNF594,IQGAP2,PTPN2,SACS,PRICKLE2,DDX31,GREB1,PCK2,CD44,HSD17B12,ADAMTSL3,ZMYM5,DHX34,TEX14,PEAR1,C11orf49,GPNMB,PIK3CB,ARMC3,SRBD1,MSH3,ITGB4,RPS6KC1,GCSH,MYCBP2,PRDX6,TNFRSF21,PRKAB2,PLRG1,ENAH,UBR5,AARS,MGA,VPS52,RNF111,MEIS3,CEP135,DPF3,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,SEMA3F,FOXRED1,MAK16,SKIL,FAM122C,VPS13D,GREB1L,DNAH2,FAM118A,SYNPO,ZNF598,PTPN14,CELSR1,DROSHA,ZHX3,OPHN1,PID1,CCDC47,TGFBR2,ANXA10,IGF2BP3,PRKCE,NAV1,ENTPD5,ASAP1,VWDE,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,SIK3,SYNGAP1,SIGMAR1,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,PMEPA1,ZZEF1,PURB,IQSEC2,ZFHX2,RTTN,PTCD2,TBKBP1,TRPM2,AMOTL1,SPATA2L,URB2,C1QTNF7,KLHL18,FOSL2,PDE3A,TRIM66,PHC2,FLAD1,TERF2IP,CHD7,ZNF827,TMEM184A,KDM2A,SHC1,NBEA,PNPLA4,KMT2A,PLEKHA4,C18orf21,ZCCHC14,RFC3,MPP6,MTIF2,WDPCP,GALK2,MED16,PNN,POLG2,TBC1D16,DHX57,DCBLD2,VDR,DNAJA3,ZNF236,ANXA2,MDN1,KLHDC4,NOLC1,PDCD11,TROVE2,NCOR2,UTP14A,MRI1,NFX1,MYNN,MLH1,GDPD5,NEDD4,LRP2BP,NISCH,PMPCA,RDX,UPF2,NLGN3,LARP4B,PLEKHG4,MBTPS2,TSHZ1,PFKFB4,WDFY3,FZD3,WDR18,KCNMA1,TBRG4,NOP58,FBXO21,ZDHHC11,HELZ,HNRNPH3,BRWD3,LRRC41,SLC37A3,PHF3,MVK,FEM1C,NF1,UBN1,PTPRA,KIF5A,TRPM6,RCHY1,ANKRD18A,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,SMARCB1,WNT2B,MRPS30,SRPRB,ANAPC1,LONRF2,YLPM1,ATG3,ANAPC10,HYAL1,POLR3B,SLC27A5,TRIP13,PRKACB,LONP1,LAMA4,TRIM13,CMIP,SLC38A1,LVRN,HDAC8,CAV1,TCTN1,CHAF1A,CDHR3,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,MKL2,RLTPR,ABCC3,TNRC6A,SLC12A7,VIPR1,PIGN,FN1,TAF1,SEC24D,DPF2,ALG8,MED13L,C11orf54,XPO7,PHGDH,RHBDD1,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,NRIP1,N4BP2,POLR1E,CPSF3L,VOPP1,KRT20,TBXAS1,WWC1,PRDM1,DNAH14,MYBBP1A,UBAP2,INTS5,HK2,EXOC4,ZFP90,KIAA1328,ZBTB24,ASH1L,PCNT,CELSR3,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,FARSA,CAMTA2,ZNF142,CPSF3,MET,TMEM14C,PTBP2,COL5A2,TFCP2,R3HDM1,ATP8B2,RAB10,RAD54B,WARS,ZC3H12A,PLIN2,ADNP,SRFBP1,USP11,TSPAN5,KLHL24,DNAJA4,SH2D3A,CLSTN2,CCDC7,SFI1,GART,CTNNBL1,DSG2,KDELC1,TTC17,AMOT,PAQR6,TEAD1,PPP1R21,ANKMY2,PHACTR2,MARS,ARHGAP32,ZNF407,NAPEPLD,SYMPK,RERE,ZNF330,CUL2,ZRANB2,MBD6,ZAK,MMP16,SLC16A10,ARHGAP27 |
| 4.152e-08 | -17.00 | stomach-carcinoma-intestinal_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-intestinal_adenocarcinoma | 7530 | 1084 | 17775 | 2278 |
ARHGAP26,CDCP1,THOC5,DPH1,CNTNAP3,AARS2,NAT10,TUBE1,SBF2,CCNL2,ABHD6,LPAR3,PDZD2,IKZF5,ZFHX3,AP1M1,MAD1L1,KDM5C,SRRM2,PPM1K,CCDC57,NRAS,KLHL23,RNMT,LIMA1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,SLC9A5,AHNAK,LRRC40,DIRAS1,VASH2,ZNF532,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,MED24,WDR60,GEMIN4,CCDC88C,PABPC1,SAMD3,NOM1,KLRD1,GATAD2B,ZNF675,STAG1,KCNQ3,ARID5B,ATAT1,USP10,ARRDC4,IRS1,DYNC1H1,TSR1,PDLIM1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,RAB11FIP4,C16orf95,PAFAH1B1,DDR2,NUP43,ST3GAL6,RPGRIP1L,TBC1D22A,SETD5,INTS12,PEG10,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,PCNXL2,KCNH3,DSP,VPS53,ZFAND3,ARHGAP21,KDM4B,ASTN2,NSMCE2,ARL13B,HOXA3,CEP170,METTL2B,CATSPERG,BAG1,MAPT,RAB30,XRRA1,ATG2B,RNASEH2B,ZNF691,TAF3,UNC13A,ACOT11,RAPGEFL1,ZNF710,RPL22L1,SPTAN1,TTPAL,DDX24,ZC3H18,RSBN1,PPIP5K2,UBC,CCDC150,NSD1,SRCAP,HERC1,ACOX1,SORCS2,MTMR1,CYP24A1,RBM33,FAM13A,NLE1,FRRS1,SRSF2,COPS4,NCKIPSD,ANKRD11,METTL8,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,PPARG,ANK2,HSPA5,TSN,LAMA2,KCNH2,ODC1,LSG1,BSN,TCF7L1,CHD3,AHNAK2,TSEN2,MAGI1,PRSS3,SMAD7,FAN1,ARID1B,SPIRE1,CEP290,NDRG4,CTR9,PNPLA3,LRSAM1,CWF19L2,SETD2,OBSCN,METTL22,ACOXL,TCF7L2,GRIK4,TTC38,CASS4,GGT7,DDX10,SH3PXD2A,SART1,OLFM2,PAPD4,SUCLG1,ARID2,SLC2A1,RIPK1,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,ZNF121,DDX60L,URB1,PLXNB1,ZNF608,NRF1,JAG1,NUP133,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,SOBP,TLCD1,ARHGAP17,AKAP8L,KIRREL2,ANKRD33B,NHSL1,TJAP1,EXO1,LMBR1L,KLF4,INTS9,EIF2B3,MUTYH,PARD3,ZNF507,ESCO1,VARS,RBM19,POGZ,SLC25A20,TTC1,CPNE7,C12orf4,LRRIQ1,MON1A,SMARCAD1,PLAC8L1,TOP3A,FERMT2,RANGAP1,PALLD,SMPDL3B,POLR3A,CDH24,NOL10,DSC2,L3MBTL3,TAF4,CSRNP1,FNTB,USP20,RBM26,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,LUZP1,PRKCA,NBEAL1,EXOC1,ZFYVE28,CHD2,ZNF646,ACADS,OSBP2,EFHC1,CAMSAP2,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,GZF1,DOT1L,OSBPL1A,TRRAP,SH3RF1,CCNT1,LUC7L3,HSPBAP1,HIC2,WDR66,BMI1,SPOCK3,NMD3,CDC42EP2,JUP,PRPF31,ST6GAL1,DLGAP4,MTUS1,TECTA,HR,SLC7A11,SCAF1,MYC,RTFDC1,EXOSC2,RREB1,PRIM2,IFNGR2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,ANGPTL4,MTR,PHF6,ATP9B,ASCC3,ALKBH3,VCAN,SPEN,MED15,BIVM,ZCCHC6,NCOR1,CNDP2,SMYD3,CPT1C,VMA21,BIRC6,TMEM104,PTPRG,PABPC1L,FLNB,RING1,NOP56,NUBPL,ASNS,SOCS6,SHF,TTC3,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,ZBTB25,MSX2,DNTTIP1,SMARCC1,MBTD1,LARGE,IFT140,TRAF3,MID1,SSH2,NOSTRIN,BRAF,KIF5C,OPA1,GIGYF2,ABL1,NEBL,ERRFI1,NAV3,TMC7,FER1L5,TTLL5,PXN,PSAT1,ZFYVE1,AGPAT4,PACS1,BMS1,SLC23A2,ZFP62,INF2,IREB2,ORC5,ATM,SVIL,APAF1,PIGM,ZNF76,ATRX,RARS2,SLC52A3,SLC30A7,DST,MYH3,ZEB1,KIAA0922,HCFC2,CEP128,SRPK2,DTNB,TNK2,DEAF1,SIRT6,ARRDC3,TFPI,MINA,KSR2,MTHFD1L,SGK2,KMT2C,TIMM44,CCDC3,TMCO1,EIF4ENIF1,CC2D1B,FAM114A2,CSMD3,ASB3,CLU,DCAF5,MTCH1,VTA1,PCSK7,SMG7,EVPL,NAMPT,RNF141,HVCN1,ZNF354A,PRF1,ZCCHC7,LRP3,AKAP11,ZNF629,MTHFD1,XPO5,ZBED4,JMJD1C,LIG4,CORIN,SYT1,AGAP1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,DMXL2,PSTPIP2,SMARCA4,TBCCD1,COBLL1,SPATS2,ARSJ,PIBF1,RIOK2,ZC3H13,RAET1E,NVL,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,MAML3,NPW,ANTXR2,GRHL3,POU2F1,DKC1,UBR4,ARMC4,HNRNPR,ZNF557,CEBPZ,RNF130,ARC,NFRKB,BRD9,SMG1,TMCC1,SUPT6H,PDE4B,ATF7IP,SEMA3E,SOGA1,ENOX1,GFM2,BMP6,STC2,RPS6KB2,TOP1,KDM6B,SLC6A16,ARNTL2,DNMBP,CRIM1,KDM5A,SCFD2,EIF5B,NAALADL2,CTIF,ZNF221,WDR35,AGTPBP1,ZSWIM6,CACNA1H,CSPP1,SYNJ1,AMBRA1,PABPC4,PCDH7,TOM1L1,NSRP1,RASSF3,PDS5B,FNIP2,ZNF148,HRG,CDK6,GNL3,PTPRM,PACRGL,RFX2,AKAP12,DCUN1D5,C10orf76,DDX3X,ZNF266,BRCA2,HERC2,CARS,EP400,KHDRBS1,SIRT7,RSF1,KCNJ14,ABCA7,KIAA1671,MCM5,CACNB2,NOC3L,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,COQ3,FMNL2,HMGCR,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,ZNF512B,RYR2,ONECUT2,ABCF1,VPS13C,LRP1B,CLASRP,LEMD3,ZNF160,MB21D2,COG5,SPRED2,ZNF516,DNM3,ABCA3,TRERF1,DDX18,BTBD2,NPAS2,PDK4,MYH9,NECAP1,SAFB2,PRKD3,ABCA12,FMNL1,PYCRL,CEP63,LSM10,FAM111B,ARHGEF10,ADAM32,TTC28,FGFR1,PDE8B,TAF2,CDC16,PEMT,HIPK2,PAM,WDR7,BRCC3,ZBTB11,YEATS2,LAMA5,ANKS1A,LRCH1,TRIM36,SESTD1,TRAK1,TGFB2,MBNL1,RSRC1,PVRL3,ACAP3,HNRNPM,SOX6,DIS3L2,FAM98A,ERICH1,ARHGAP39,R3HDM2,FAM126B,ZNF467,PDE3B,DDX49,CASC1,RPA1,RARS,TRIB3,ETFDH,BAZ2B,PXDN,POLE2,ARID3B,PLPPR2,STX1A,PTPN4,SLC25A19,SLCO5A1,GPAM,DOCK6,KDM4C,ANAPC4,CORO2B,FAM227A,POLR1A,PPARGC1B,MFGE8,CSNK2A1,RNF43,TMEM132A,TTI1,SEC16A,ABL2,DHX33,MARVELD2,TRMU,ZNF85,ETV1,SF3A1,PTPRK,FLNC,CHD9,SLC3A2,ABCC4,SKIV2L2,BAZ2A,MED27,NOL6,BRCA1,KIF16B,MSRA,TP53BP1,PER1,EEFSEC,CCDC146,TECPR2,SOCS4,TNFRSF1A,SGSM2,RNF214,XYLB,OXNAD1,AOC3,SARS,ITPRIP,RLF,DNAH1,KIAA1958,PDE10A,PPIL2,TIMELESS,GTF2H1,SYNJ2,GMDS,NT5E,CAMKK2,TRAPPC9,TLE3,HOMER2,ZNFX1,SUPT5H,VAC14,PWP1,ATXN7,SPAG9,FAM135A,PALB2,SYNCRIP,DNAH17,NAPA,TESC,LPCAT2,GPR143,ZNF83,RNF24,CAD,FSIP2,ARMC5,C15orf40,HIRIP3,ANO8,ZFP37,CORO1A,CASP10,TMEM200A,KAT8,SKIV2L,PCGF3,EVL,THSD4,SLC35F2,TMEM123,AKAP13,ENC1,ARL5B,NUP214,USP36,BTBD11,SMAD3,RANBP2,SLC30A3,RBBP8,CLEC16A,ZNF333,ITGA2,TSSC1,PRRT3,PUS1,NFASC,AP2S1,ATXN7L2,UNC13D,MAP1S,C14orf159,RMI1,ZNF594,IQGAP2,PTPN2,SACS,PRICKLE2,DDX31,GREB1,PCK2,CD44,HSD17B12,ADAMTSL3,ZMYM5,DHX34,TEX14,PEAR1,C11orf49,GPNMB,PIK3CB,ARMC3,SRBD1,MSH3,ITGB4,RPS6KC1,GCSH,MYCBP2,PRDX6,TNFRSF21,PRKAB2,PLRG1,ENAH,UBR5,AARS,MGA,VPS52,RNF111,MEIS3,CEP135,DPF3,NR6A1,ALDH1L2,NOL8,EYA3,TCEB3,CUX1,SEMA3F,FOXRED1,MAK16,SKIL,FAM122C,VPS13D,GREB1L,DNAH2,FAM118A,SYNPO,ZNF598,PTPN14,CELSR1,DROSHA,ZHX3,OPHN1,PID1,CCDC47,TGFBR2,ANXA10,IGF2BP3,PRKCE,NAV1,ENTPD5,ASAP1,VWDE,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,TERF2,SCAF11,SIK3,SYNGAP1,SIGMAR1,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,PMEPA1,ZZEF1,PURB,IQSEC2,ZFHX2,RTTN,PTCD2,TBKBP1,TRPM2,AMOTL1,SPATA2L,URB2,C1QTNF7,KLHL18,FOSL2,PDE3A,TRIM66,PHC2,FLAD1,TERF2IP,CHD7,ZNF827,TMEM184A,KDM2A,SHC1,NBEA,PNPLA4,KMT2A,PLEKHA4,C18orf21,ZCCHC14,RFC3,MPP6,MTIF2,WDPCP,GALK2,MED16,PNN,POLG2,TBC1D16,DHX57,DCBLD2,VDR,DNAJA3,ZNF236,ANXA2,MDN1,KLHDC4,NOLC1,PDCD11,TROVE2,NCOR2,UTP14A,MRI1,NFX1,MYNN,MLH1,GDPD5,NEDD4,LRP2BP,NISCH,PMPCA,RDX,UPF2,NLGN3,LARP4B,PLEKHG4,MBTPS2,TSHZ1,PFKFB4,WDFY3,FZD3,WDR18,KCNMA1,TBRG4,NOP58,FBXO21,ZDHHC11,HELZ,HNRNPH3,BRWD3,LRRC41,SLC37A3,PHF3,MVK,FEM1C,NF1,UBN1,PTPRA,KIF5A,TRPM6,RCHY1,ANKRD18A,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,SMARCB1,WNT2B,MRPS30,SRPRB,ANAPC1,LONRF2,YLPM1,ATG3,ANAPC10,HYAL1,POLR3B,SLC27A5,TRIP13,PRKACB,LONP1,LAMA4,TRIM13,CMIP,SLC38A1,LVRN,HDAC8,CAV1,TCTN1,CHAF1A,CDHR3,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,MKL2,RLTPR,ABCC3,TNRC6A,SLC12A7,VIPR1,PIGN,FN1,TAF1,SEC24D,DPF2,ALG8,MED13L,C11orf54,XPO7,PHGDH,RHBDD1,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,NRIP1,N4BP2,POLR1E,CPSF3L,VOPP1,KRT20,TBXAS1,WWC1,PRDM1,DNAH14,MYBBP1A,UBAP2,INTS5,HK2,EXOC4,ZFP90,KIAA1328,ZBTB24,ASH1L,PCNT,CELSR3,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,FARSA,CAMTA2,ZNF142,CPSF3,MET,TMEM14C,PTBP2,COL5A2,TFCP2,R3HDM1,ATP8B2,RAB10,RAD54B,WARS,ZC3H12A,PLIN2,ADNP,SRFBP1,USP11,TSPAN5,KLHL24,DNAJA4,SH2D3A,CLSTN2,CCDC7,SFI1,GART,CTNNBL1,DSG2,KDELC1,TTC17,AMOT,PAQR6,TEAD1,PPP1R21,ANKMY2,PHACTR2,MARS,ARHGAP32,ZNF407,NAPEPLD,SYMPK,RERE,ZNF330,CUL2,ZRANB2,MBD6,ZAK,MMP16,SLC16A10,ARHGAP27 |
| 4.183e-08 | -16.99 | soft_tissue | COSMIC cancer mutations | soft_tissue | 6065 | 892 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CNTNAP3,DCP1B,CACNA1H,SBF2,CSPP1,CCNL2,SYNJ1,SKI,TOM1L1,PCDH7,C1orf159,PDZD2,ZFHX3,ATP5G2,FAAH2,RABGAP1L,MAD1L1,PDS5B,ZNF148,HRG,AVEN,SRRM2,CNTNAP3B,CCDC57,NRAS,KLHL23,PTPRM,UPP1,NFIA,KIF15,RFX2,WDHD1,ABCC2,SLC50A1,AHNAK,BRCA2,RUNX1,CARS,HERC2,EP400,TMEM63C,SIRT7,NHS,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,SLC1A1,ABCA7,SLC39A11,RSPRY1,SH2B3,RBM20,DDX56,UBE3A,DHX37,KIAA1671,INTS7,MED24,ANP32B,GEMIN4,NOC3L,CCDC88C,COQ3,ZNF518B,AGL,FMNL2,SAMD3,NOM1,HMGCR,COL17A1,STAG1,KCNQ3,MYO10,RB1CC1,PRDM16,ARID5B,EPS15L1,RYR2,ATAT1,USP10,SMARCD3,MAP7D1,CPT1A,TRIM37,EVI5,ONECUT2,NCDN,IRS1,DYNC1H1,VPS13C,LRP1B,TASP1,GTF2A1,GSTO2,NME7,PDLIM1,TRAP1,ZNF160,WDR33,PDLIM5,MB21D2,ARHGAP10,COG5,ZNF516,PAFAH1B1,VTI1A,MYH9,AGAP6,ISG20L2,TUBB6,ST3GAL6,SAFB2,RPGRIP1L,ABCA12,TBC1D22A,SETD5,FMNL1,WAC,CLCN6,MSH4,PEG10,KIAA1549,DENND1A,GARS,KMT2D,FAM111B,EIF3J,ARHGEF10,SLCO6A1,PCNXL2,GSTCD,TTC28,DSP,VPS53,MAT2A,FGFR1,PDE8B,ZFAND3,PES1,CDC16,KDM4B,ASTN2,NSMCE2,HIPK2,METTL6,POLR3E,WDR7,PAM,FUS,ANKS1A,LAMA5,METTL2B,YEATS2,CATSPERG,BAG1,MAPT,TRIM36,MORC2,COMMD10,HMGA2,ZNF786,XPC,ATG2B,BHLHE40,RSRC1,MBNL1,PSMF1,NPRL2,TAF3,CFDP1,UNC13A,ACOT11,ARHGAP1,ACTR3B,SOX6,HNRNPM,SPTAN1,DIS3L2,DDHD1,C21orf58,VPS37A,ERICH1,CLYBL,POLK,ZC3H18,LDHA,ZNF467,UBE2K,PDE3B,CASC1,CCDC150,RPA1,ETFDH,SRCAP,RARS,NSD1,BAZ2B,PXDN,HERC1,ACOX1,SLCO5A1,PTPN4,AEN,GPAM,SORCS2,DOCK6,CORO2B,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,PPARGC1B,TFIP11,MFGE8,SLC25A21,RNF43,FAM13A,SEC16A,COX10,SCAF8,FRRS1,MAP2K3,SRSF2,TRMU,XRCC2,ANKRD11,RAN,MPST,SF3A1,VPS13B,METTL1,FLNC,DSC3,FMNL3,CHD9,ABCC4,MIOS,BAZ2A,SKIV2L2,PPARG,ANK2,COL4A3BP,LAMA2,BRCA1,KCNH2,ODC1,CRYBG3,PEX1,BSN,DYRK1B,GLS,TCF7L1,MSRA,TP53BP1,PER1,CCDC146,TNFRSF1A,ADAM9,CTU2,XYLB,ITFG1,PRSS3,SMAD7,MEX3A,MAPK8IP3,HES6,RLF,ARID1B,DNAH1,DOPEY1,KIAA1958,CEP290,PDE10A,VAPB,TIMELESS,SYNJ2,LRSAM1,CWF19L2,SNX29,NT5E,TRAPPC9,CRADD,SETD2,HAUS6,BCS1L,OBSCN,CYB5B,ACOXL,NR2F1,TCF7L2,VAC14,TBC1D2,GRIK4,ATXN7,FAM135A,SPAG9,PALB2,SNAP23,DNAH17,SNX24,PPP1R12B,SIL1,CASS4,ARHGAP12,DDX10,PRKAR2A,BCCIP,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,ZNF83,LPCAT3,SSBP2,DENND3,RADIL,ZNF121,URB1,DDX60L,PELP1,PLXNB1,FDX1,KDM1A,ANKRD13A,ZNF608,JAG1,NUP133,GRIN2C,UBR1,ARMC5,DNAJB6,CCDC40,ZFP37,MYH15,HIBCH,ANO8,CASP10,CTC1,TMEM200A,KDM3B,SOBP,SEC24A,WDR36,PCGF3,AKAP8L,SSFA2,GLTSCR2,THSD4,RAB7A,ANKRD33B,MANBAL,VIM,AKAP13,NHSL1,NUP214,ATP5D,BTBD11,EXO1,SMAD3,RANBP2,SLC30A3,LMBR1L,SIX5,ZNF333,CLEC16A,KLF4,ITGA2,ATG7,TSSC1,INTS9,PRRT3,NFASC,PUS1,MUTYH,PARD3,ATXN7L2,ZNF507,UNC13D,DMGDH,C14orf159,MAP1S,VARS,RBM19,FOXP1,RMI1,POGZ,BZW2,ZNF594,ANKRD54,IQGAP2,PTPN2,FAM50A,SACS,CWC27,TMEM161A,PRICKLE2,DDX31,POLR1B,CPNE7,CD44,HSD17B12,FAM71E1,ADAMTSL3,LRRIQ1,C22orf34,TPM4,PEAR1,FERMT2,RAP1GDS1,ARHGEF12,C11orf49,PALLD,RHOT2,PIK3CB,ARMC3,SMPDL3B,NEU1,POLR3G,ZRANB3,TPD52L2,NOL10,SRBD1,DSC2,TAF4,SET,GLG1,BCAS3,USP20,RBPJ,NR2F2,RPS6KC1,C6orf223,MIPOL1,ZNF292,MYCBP2,CGN,TMEM109,ENAH,NBEAL1,AARS,UBR5,RAC3,LPIN1,GIPR,RNF111,CHD2,ME1,CEP135,SEH1L,CSGALNACT2,ZNF646,TBC1D8,ACADS,SLC38A6,CUX1,TCEB3,EFHC1,ZDHHC14,DENND4A,SON,PLCXD2,DOT1L,OSBPL1A,TRRAP,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,WDR66,TXN2,BLMH,ZNF598,NMD3,SPOCK3,PTPN14,WDR75,IFT57,JUP,CELSR1,ZHX3,LARS2,DLGAP4,OPHN1,PID1,CCDC47,PRPF39,SSR4,CD226,MTUS1,IGF2BP3,ANXA10,FAM192A,PRKCE,TECTA,NAV1,HR,TSPAN2,ASAP1,SCAF1,COPS3,MYC,ATIC,VWDE,PIGG,MFAP2,GTF3C3,IGF2BP1,CNOT4,FDFT1,SIK3,EXOSC2,RREB1,PRIM2,POLA1,RAPGEF4,RAP1GAP2,KIAA0586,TTYH2,PTPN12,ARID1A,PLCB1,MTR,SLC26A11,ANGPTL4,ARIH2,LYRM7,ATP9B,DAGLA,SEC31A,ZNF425,EPRS,ASCC3,KIDINS220,PMEPA1,VCAN,SRP68,ZZEF1,D2HGDH,MED15,DPEP1,UMPS,NCOR1,CNDP2,MAP2K4,ZFHX2,CPT1C,RTTN,TBKBP1,AMOTL1,SYT17,TRPM2,LIN28B,HFM1,KIAA0232,NDUFB5,PTPRG,AP1B1,SLC25A44,PABPC1L,LTB4R,TRIM66,IGSF1,PDE3A,PAIP2,CHD7,ZNF827,DECR1,TMEM184A,KDM2A,VGF,DTNBP1,SHF,NBEA,TTC3,PNPLA4,ZCCHC14,RFC4,MPP6,GON4L,C1orf228,WDPCP,DLG4,KIAA1586,GNL1,SATB2,MEGF11,MED16,TBC1D16,STK10,ERC1,DHX57,DCBLD2,HTR7,CAMK2D,DNAJA3,G6PD,ZNF236,LARGE,ACP1,IFT140,CBWD1,MDN1,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,TTC27,C10orf2,TCF3,NFX1,FARS2,RCAN1,RTN4,MLH1,DNAJC22,OPA1,INPP1,GIGYF2,REEP5,FAM8A1,NEDD4,ABL1,NEBL,PMPCA,UPF2,RDX,FER1L5,PFKFB4,TTLL5,WDFY3,PACS1,BMS1,OASL,MMAA,YIF1A,ZFP62,KLHL22,DDX50,HELZ,STX18,ATM,MYOM2,APAF1,NDUFS5,BRWD3,LRRC41,IMMP2L,LETM1,MVK,PHF3,NF1,ATRX,RARS2,KIF5A,SLC52A3,FANCD2,TRPM6,ZNF107,PLOD1,SIRT2,BCOR,STK33,SNAPC4,EDC3,SLC30A7,SMARCB1,RTN1,ZNF804A,DST,ANAPC1,THADA,YLPM1,LONRF2,JAZF1,MYH3,GPATCH1,B3GNTL1,KIAA0922,POLR3B,PCOLCE2,NDUFA6,CCDC121,OGG1,CARM1,CEP128,DTNB,DEAF1,GPM6A,FBXW4,SKAP2,ITPA,CMIP,SIRT6,ARRDC3,TMEM216,KSR2,HDAC8,MTHFD1L,KMT2C,SOX4,TCTN1,SERGEF,CHAF1A,CCDC3,TMEM132B,GEMIN5,EPN2,SUFU,HLCS,DNAJC1,FAM114A2,CSMD3,ASB3,EME1,CLU,ZC3H8,MTCH1,TNRC6A,VIPR1,SLC12A7,DCTN3,CHST11,FN1,SCART1,ZCCHC8,PAX2,PCSK7,MED13L,SMG7,EVPL,QSER1,RHBDD1,SIPA1L3,MCAM,WDR27,ISPD,SEMA3D,CCDC124,ZCCHC7,PRF1,NRIP1,ATP6V0D1,LRP3,AKAP11,N4BP2,ZNF629,MTHFD1,RANBP6,HBG2,KRT20,PDE4A,ELP3,ZBED4,JMJD1C,WWC1,C11orf65,EIF2A,PRDM1,CORIN,ANKRD20A4,AGAP1,DNAH14,ISG15,SYCP2L,BICD1,MYBBP1A,EP400NL,FAT1,SDCCAG8,EXOC4,HK2,TMEM117,CDKAL1,KIAA1328,ZFP90,TMEM182,TBCK,PDSS2,TCF12,DMXL2,CHMP2A,FEZ2,ASH1L,PCNT,CELSR3,TMEM183A,TNXB,MYO7A,SMARCA4,COBLL1,GBF1,VPS18,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,ZNF142,FHIT,ADCK4,MET,VCL,ZNF460,HTRA2,AUP1,MAML3,NARS2,RTN4RL2,FAM172A,TFCP2,PARP2,GRHL3,ATXN1,R3HDM1,METTL15,MRRF,EDEM2,ATP8B2,UBR4,TPK1,ARMC4,ALAD,DUS3L,IKZF4,HYAL3,SRFBP1,SCARB1,DISP1,SMG1,TMCC1,SH2D3A,DYM,CMTM8,DBF4,NSUN6,CLSTN2,ATF7IP,SEMA3E,CCDC7,PPP1R1C,MFHAS1,GFM2,MFSD10,SFI1,PRKCH,SCN1B,SEC24C,DSG2,KDELC1,SHMT2,TTC17,LDLRAD3,FBL,ERI3,DMRT1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,CRIM1,METTL23,SCFD2,ASAP3,MEN1,TMEM187,ZNF407,EIF5B,NAALADL2,SYMPK,RERE,DAGLB,WDR35,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,SLC16A10,ZSWIM6 |
| 4.209e-08 | -16.98 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | 1192 | 216 | 17758 | 2279 |
PTP4A1,ZNF76,BCAS4,PPARGC1B,PLRG1,SLC25A21,FANCD2,ZNF107,CSNK2A1,TUBE1,SLC29A1,HLTF,NUP160,UBR5,AARS,CIAPIN1,RAP1A,SRSF2,PHF5A,PMAIP1,DHX33,PDS5B,METTL8,JOSD1,FNIP2,ME1,POLE3,CEP135,TRIP13,SEH1L,TMPO,SF3A1,SRPK2,DPF3,GDAP1,SLC3A2,NRAS,TXLNG,ZNF680,KLHL23,TSN,CUX1,PACRGL,KIF15,AKAP12,PSMG1,WDHD1,CAV1,BRCA1,MCM2,CHAF1A,TMEM132B,GEMIN5,DDX3X,BRCA2,RAD18,XPNPEP1,PRPF4,EME1,TSEN2,BLMH,MCM6,AK2,ZCCHC8,XPO7,SH2B3,RSPRY1,MLX,UBE3A,EIF2S2,SLC38A5,ASAP1,USPL1,MCM5,CACNB2,COPS3,TIMELESS,IGF2BP1,GEMIN4,NOC3L,CWF19L2,CAV2,N4BP2,PRPS1,PPA1,SERBP1,MYB,NOM1,MTHFD1,SIK3,EXOSC2,IFRD1,STAG1,ALG6,KIAA1143,PRIM2,PPAT,POLA1,XPO5,HAUS6,USP10,EIF2A,CYB5B,AGAP1,ZNF850,ARIH2,PGD,POP1,TSR1,ATAD5,MTHFD2,MYBBP1A,KPNA1,GTF2A1,CDK9,HK2,SLC16A1,SQLE,CDKAL1,SENP3,UMPS,HS2ST1,RTTN,BCCIP,SPRED2,DDX18,MAB21L3,PPP2R2A,FAM122B,ISG20L2,TUBB6,FDX1,NOP56,PRKD3,ASNS,DUS4L,PPID,ERI1,UBR1,UCHL5,ZDHHC6,ETF1,CMPK1,LSM10,CASP8AP2,NARS2,RFC4,ARHGAP17,MPP6,RFC3,SLC35F2,GALK2,DKC1,SERP1,MAT2A,RAD54B,TAF2,EXO1,TAMM41,SMARCC1,HNRNPR,COPS5,ABHD3,ACP1,TRAF3,PUS1,BRCC3,ZNF507,COMMD10,MCM10,DBF4,C1orf226,ZNF280C,CLSTN2,ID2,LIAS,RMI1,GFM2,NEDD4,DCTPP1,ADH5,SNW1,GART,SUV39H2,PVRL3,SELT,PCK2,SNAPC5,DDHD1,PXN,TRNP1,PSAT1,GINS3,PSMC3IP,ABCF2,MRPS10,SCMH1,RANGAP1,HIST1H4J,EIF5B,RPA1,ZRANB3,TRIB3,TMEM237,POLE2,COQ9,SET,ORC5,STX18,SRD5A3,RNF138,AEN,DNAJC12,MYOM2,GPAM,NR2F2 |
| 4.404e-08 | -16.94 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | 597 | 123 | 17758 | 2279 |
CYP24A1,PTCD2,ID1,TMEM109,LAGE3,TMEM177,POP5,ARSJ,HMOX2,PCDH7,PCYOX1L,NUBPL,FARSA,JAG1,YLPM1,PYCRL,IPP,CORO1A,PNPLA4,VCL,TRMT12,TRIM14,ACSL5,SLC38A6,MALL,DEAF1,PMS1,RFC3,PARP2,TCEB3,KIF15,PNN,ENC1,MAT2A,RAD54B,CCDC28B,ZBTB25,UBTF,EXO1,WDR5B,WDR7,INTS9,BDH2,H2AFX,SLC25A11,GALNT10,BRCC3,TSEN2,TXN2,SYNPO,NCOR2,MCM10,AK2,PIGN,STX8,FN1,ZHX3,DBF4,ALG8,SLC25A12,DPM3,TGFB2,TIMM10,TGFBR2,FAM8A1,TMCO6,ETFB,HDDC2,SLC25A20,IGF2BP3,MRPS11,DCTPP1,FAM192A,ZNF239,RNFT2,SUB1,GATC,SURF2,IFIT5,TRIAP1,KDELC1,COPS7B,GEMIN4,EXOSC4,FBXO31,CAV2,MBTPS2,PCSK6,NAV3,RPS6KB2,TTPAL,VOPP1,RANBP6,BDNF,TIMM8B,ANAPC13,ALG6,CRIM1,ELOVL6,TPM4,BCS1L,ZNF512B,WWC1,EXOG,NR2F1,ISG15,TBC1D2,IRS1,TASP1,POLE2,EHMT2,NME7,FGFBP1,INTS5,VCAN,CCDC85B,HK2,RRAGA,FNTB,HMBS,TBL1X,PDLIM5,MTMR1 |
| 4.613e-08 | -16.89 | Helicase_ATP-bd | interpro domains | IPR014001 | 110 | 36 | 18293 | 2341 |
EP400,ATRX,DDX18,HFM1,DDX19A,SMARCA4,HLTF,DHX35,CHD5,DDX60L,CHD7,DDX56,DHX37,DHX33,CHD2,DDX31,SKIV2L,CHD9,DDX28,DDX24,DDX41,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,RAD54B,ZRANB3,DDX3X,SRCAP,ASCC3,DDX50,CHD3,DDX10 |
| 5.209e-08 | -16.77 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 221 | 58 | 17758 | 2279 |
MCM6,MCM10,TMEM104,SLC29A1,AP1B1,FLNB,NOS1AP,NOP56,HR,GART,LONRF2,MCM5,MYC,XRCC2,STC2,GREB1,RAPGEFL1,POLR1B,PXK,CD44,LDLRAD3,NRIP1,YARS,TMEM120B,SEH1L,MYB,RFC3,GINS3,BCS1L,NOL6,WDHD1,MARS,BRCA1,MTHFD1L,DKC1,MCM2,CHAF1A,EXO1,SLC7A1,RBBP8,MYBBP1A,POLE2,HIF1A,SNX24,HSPB8,SLC16A1,SVIL,DNAJC12,FKBP5,SCARB1,TPM1,SEPT5,NOLC1,DDX10,PDCD11,PKIB,MAPT,NR2C2AP |
| 5.220e-08 | -16.77 | ribosome biogenesis | biological process | GO:0042254 | 229 | 60 | 16441 | 2138 |
SART1,DROSHA,UTP14A,MRPL10,ISG20L2,NLE1,SBDS,NOP56,MRPS11,METTL16,CHD7,RRN3,DDX56,RPS16,MPHOSPH10,ERI1,NOP16,NVL,ZNHIT6,DDX31,RAN,GEMIN4,EXOSC4,FBL,ERI3,UTP4,FTSJ3,DIS3L2,NOM1,WDR36,DDX28,EXOSC2,SNU13,SKIV2L2,GNL3,NPM3,NOL8,WBSCR22,MINA,NOL6,UTP15,METTL15,GNL1,BMS1,EIF2A,DKC1,ABCF1,LSG1,NOP58,MRPL36,PES1,DDX3X,ZNF622,TSR1,SRFBP1,HEATR1,MDN1,PDCD11,NOLC1,NMD3 |
| 5.807e-08 | -16.66 | MTOR_UP.N4.V1_UP | MSigDB lists | MTOR_UP.N4.V1_UP | 190 | 52 | 17758 | 2279 |
CARS,SARS,SPRED2,ASCC1,SEC24D,LARS2,TRPM6,VARS,CHAC1,BHLHE40,PHGDH,COX10,ABHD6,CUTC,DDIT4,ASNS,SLC7A11,PAK1IP1,PCK2,PTPRK,ULBP1,RABEPK,ADARB1,DDN,DBN1,IFRD1,SLC3A2,LIMA1,PCCA,ELOVL6,TBRG4,PHACTR2,MARS,GALK2,PLCB1,RBM28,HERPUD1,POLR3G,PYCR1,TIMM44,SLC39A14,TRIB3,HYAL3,NME7,ARL4A,ADAM9,EIF2B3,DHCR7,SYNPO,DDIT3,SLC43A1,GALE |
| 6.450e-08 | -16.56 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | 379 | 86 | 17758 | 2279 |
SRM,LETM1,SLC48A1,URB2,POLR1A,SMARCA4,SLC25A44,PRKCA,SLC6A8,HSPA1A,PABPC4,FDX1,MAP2K3,NOP56,SRPRB,ANKRD13A,DHX33,SOCS6,ETF1,TSPAN14,AVEN,CDK6,FTSJ3,LONP1,METTL1,GON4L,ANKRD33B,NOL8,MARCKSL1,SUMO3,PNN,ODC1,GEMIN5,GLS,DDX3X,CAMK2D,DUS3L,SMARCC1,CCNT1,FAM206A,G6PD,LUC7L3,ALKBH1,PRPF4,CCNB1IP1,TPM1,NRP1,NOLC1,PDCD11,TXN2,TSPAN5,ZMAT3,LETMD1,IKBKAP,RBM19,MFSD10,MAN1A1,C6orf48,GTF2H1,PTGS1,SAMD4A,MTHFD1,TTPAL,MSI2,FAM98A,PPAT,MYO10,ELOVL6,ZC3H18,XPO5,BMS1,OASL,MTR,HSPA1B,PGD,POP1,TSR1,MYBBP1A,SYNCRIP,VCAN,USP20,AEN,PPP1R12B,SENP3,XPO6,IPO4 |
| 6.506e-08 | -16.55 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 15563 | 2070 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,ABCC2,MCM2,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,CDC73,PITPNM1,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,ATG2B,RNASEH2B,POLR3D,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,PNMA1,SPTAN1,DDX24,ZC4H2,LDHA,CCDC113,CCDC150,MRPL36,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,NUP133,BCAP29,PRPF19,KDM3B,SOBP,SSFA2,TEX19,KIRREL2,RAB7A,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,ZCCHC7,PRF1,AKAP11,MTHFD1,MSI2,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,SREBF2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,NOC3L,PRMT5,CALN1,COQ3,AGL,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,SPRED2,ABCA3,NPAS2,ATP6V1A,HSPA1A,PRKD3,PYCRL,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,RAD51B,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,CAD,DUS4L,UBR1,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,SIK3,DDX28,SIGMAR1,AOC2,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,PURB,UMPS,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,FOSL2,LTB4R,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,SCAMP3,CA11,TTC27,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,MSH4,TRMT12,LYST,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,CYP24A1,CUL7,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ANKRD13A,ZNF608,JAG1,IDI1,GRIN2C,AHCYL1,IPO11,ARHGAP17,VIM,CA5B,LMBR1L,KLF4,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,RANGAP1,C8orf33,SMPDL3B,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,DDX60,DENND4A,SON,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,CDC42EP2,PRPF31,LARS2,DLGAP4,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,ARID1A,TPRA1,EHBP1,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,TTC3,PREX1,PCMT1,SATB2,GNL1,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,SNX27,CHMP2A,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,PKNOX1,TOP1,KDM6B,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,NIT1,ZSWIM6,GNB3,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,RASSF3,RABGAP1L,FAAH2,C12orf76,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,PACRGL,AKAP12,MCL1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,DNM3,ZNF516,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,ATF7IP2,LGALS1,ATP6V0A1,FGFR1,PES1,TAF2,GNG2,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,TADA3,PVRL3,SOX6,DIS3L2,ULBP1,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TRIB3,TOE1,RARS,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,DLX2,CHMP4C,SEPHS2,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,PPIL2,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,BCS1L,WDR25,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,PTPN2,SACS,NDUFV1,CWC27,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,TPM4,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,MEIS3,CEP135,PRADC1,FUT11,SLC38A6,GNG7,EYA3,TCEB3,CUX1,SEMA3F,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,TXN2,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,SCAF11,ADARB1,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,SERF2,KIDINS220,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,RIBC2,URB2,ZBTB37,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,TERF2IP,PHC2,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 6.561e-08 | -16.54 | thyroid-carcinoma | COSMIC cancer mutations | thyroid-carcinoma | 4286 | 652 | 17775 | 2278 |
ARHGAP26,CDCP1,DPH1,CNTNAP3,MRPL10,NAT10,MKS1,SBF2,HMOX2,SLC6A8,ABHD6,CIAPIN1,AMBRA1,PDZD2,SREBF2,ZFHX3,SYN2,LETM2,PDS5B,ZNF148,SRRM2,NRAS,WLS,NFIA,KIF15,AKAP12,ABCC2,C10orf76,RBM28,STOML2,AHNAK,BRCA2,RAD18,MPV17,RIOK1,ZNF532,MEF2C,TNNC1,CARS,CLDN15,KHDRBS1,TRIO,NHS,RSF1,PITPNM1,RSPRY1,CHN1,SH2B3,EIF2S2,DHX37,CCDC88C,AGL,PABPC1,FADS1,GATAD2B,IFRD1,STAG1,MYO10,RB1CC1,PRDM16,ARID5B,EPS15L1,ZNF512B,RYR2,USP10,SMARCD3,IMPDH2,CPT1A,USP46,ABCF1,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,KPNA1,EHMT2,LEMD3,ZNF160,GPN1,CNOT6,WDR33,SGSM3,COG5,SPRED2,ABCA3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,VTI1A,GRINA,MCM9,PRKD3,ABCA12,ACD,SETD5,FMNL1,CLCN6,MTHFD2L,MGLL,ZC3H3,LYST,PMS1,FAM111B,NPM3,ZNF480,SLCO6A1,PCNXL2,NUDT15,DSP,VPS53,FGFR1,SLC39A14,ZFAND3,TAF2,FBXL5,HLA-DMA,ASTN2,WDR7,BRCC3,ANKS1A,LAMA5,METTL2B,YEATS2,TRIM36,ZNF786,SHQ1,SESTD1,ID2,ATG2B,IP6K2,TGFB2,POM121,POLR3D,NPRL2,GATC,NOP16,UNC13A,RAPGEFL1,ZNF710,RPL22L1,SPTAN1,ULBP1,ZC3H18,LDHA,NXN,ZNF467,UBC,CCDC150,ANXA1,TRIB3,SRCAP,NSD1,BAZ2B,ARID3B,PSAP,GPAM,MTMR1,DOCK6,KDM4C,CYP24A1,POLR1A,FAM13A,TTI1,TMEM132A,SEC16A,SCAF8,FRRS1,ABL2,AMPD3,SRSF2,ARHGAP18,PHKA1,NCKIPSD,ANKRD11,ETV1,SF3A1,PTPRK,VPS13B,FLNC,DSC3,DBN1,FMNL3,CHD9,ZNF414,ANK2,GDPD1,HSPA5,NOL6,ATG12,LAMA2,BRCA1,KCNH2,ZNF91,PEX1,BSN,DYRK1B,TCF7L1,TP53BP1,CHD3,TECPR2,RAD51B,SGSM2,MAGI1,BEND6,RNF214,XYLB,CLK1,FAN1,ZIC2,ARID1B,DNAH1,KIAA1958,ABCA5,CEP290,GMDS,LRSAM1,NT5E,CAMKK2,LAMC1,USP49,SETD2,HAUS6,OBSCN,ZNFX1,ACOXL,TCF7L2,VAC14,TBC1D2,SPAG9,PALB2,SYNCRIP,TTC38,DNAH17,SH3PXD2A,PRKAR2A,MPI,SART1,ARID2,OSBPL9,ZNF83,TNKS1BP1,SEMA6A,DDX60L,PLXNB1,ZNF608,NUP133,UBR1,FSIP2,CYB5D1,ANKRD24,CCDC40,MYH15,ETF1,RNF2,AKNAD1,PRMT3,IPO11,CTC1,KAT8,ARHGAP17,AKAP8L,SSFA2,GLTSCR2,CPOX,AKAP13,ENC1,NUP214,USP36,ZNF251,RANBP2,SIX5,CLEC16A,ITGA2,ZNF436,INTS9,PARD3,ATXN7L2,ZNF507,UNC13D,DMGDH,MAP3K13,ARFIP2,VARS,ZNF346,POGZ,ANKRD54,PTPN2,SACS,ANXA7,HIST2H3D,PRICKLE2,POLR1B,CD44,PCK2,AP4S1,ADAMTSL3,KRTCAP3,TEX14,HIST1H4J,GPNMB,RHOT2,PIK3CB,ARMC3,CDH24,CACNB1,SAMD5,SRBD1,DSC2,GLG1,BCAS3,USP20,RBPJ,KIF1B,MIPOL1,ZNF292,MYCBP2,POLB,CGN,LUZP1,PRKCSH,TMEM109,UBR5,MGA,ZFYVE28,VPS52,CSGALNACT2,SPAG6,ZNF646,DPF3,ATG9A,CUX1,TCEB3,CAMSAP2,ZDHHC14,DOT1L,SPOP,GZF1,SKIL,TRRAP,CCNT1,LUC7L3,CFD,VPS13D,XPNPEP1,DNAH2,WDR66,NRP1,RFXAP,SPOCK3,PRPF38B,ANKRD17,LARS2,ZHX3,DLGAP4,GTF2IRD1,PRPF39,TGFBR2,TECTA,NAV1,PI4KB,SLC7A11,ASAP1,SCAF1,MYC,PRPS1,ADARB1,SCAF11,RREB1,PCCA,RDH10,PLCB1,EHBP1,ANGPTL4,PHF6,DAGLA,ASCC3,EPRS,SERF2,HIF1A,UBAP1,VCAN,ZZEF1,SRP68,D2HGDH,MED15,SQLE,NCOR1,IQSEC2,MAP2K4,CPT1C,RTTN,PTCD2,AMOTL1,TRPM2,SYT17,BIRC6,HFM1,KIAA0232,LTB4R,PDE3A,IGSF1,CHD7,SLX4,SHC1,KDM2A,PPID,DTNBP1,TTC3,SERPINH1,KMT2A,CDK12,GON4L,MTIF2,WDPCP,PREX1,LRRC8A,MARCH6,MEGF11,MED16,PNN,TBC1D16,ERC1,VDR,DNTTIP1,WDR5B,G6PD,ZNF236,H2AFX,LARGE,ALKBH1,SLC4A7,IFT140,MDN1,TBXA2R,PDCD11,NOLC1,SETD6,TROVE2,NCOR2,BRAF,TTC27,TCF3,ZNF280C,NFX1,SLC25A12,MLH1,MON2,OPA1,DNAJC22,GIGYF2,NEDD4,ABL1,LRP2BP,NISCH,DYNC2H1,ERRFI1,PLEKHG4,NAV3,FAM120B,PFKFB4,TMC7,SLC40A1,TTLL5,PSAT1,ZFYVE1,WDFY3,FZD3,KCNMA1,KLF6,MMAA,SLC23A2,ZNF155,HELZ,SVIL,ATM,MYOM2,APAF1,LETM1,PHF3,UBN1,NF1,ATRX,FANCD2,SLC29A1,BCOR,SNAPC4,MRPS30,SMARCB1,PCYOX1L,DST,ZNF804A,RAP1A,YLPM1,LONRF2,SLC39A7,GPR87,ANAPC11,MYH3,GPATCH1,KIAA0922,POLR3B,B3GNTL1,LONP1,CEP128,SRPK2,LAMA4,DEAF1,DTNB,TRIM13,SKAP2,ITPA,TFPI,KSR2,HDAC8,MTHFD1L,KMT2C,CHAF1A,GEMIN5,TMEM132B,GATA6,HLCS,SUFU,TRMT5,DNAJC1,MKL2,CTAGE5,CSMD3,GALNT10,DCAF5,CHST11,FN1,SEC24D,TAF1,VTA1,PCSK7,MED13L,SMG7,EVPL,QSER1,PHGDH,CEP164,ELL,ATXN2,NRIP1,ATP6V0D1,N4BP2,AKAP11,MTHFD1,ZNF234,PPAT,JMJD1C,LIG4,WWC1,C11orf65,CORIN,SYT1,AGAP1,SYCP2L,ATAD5,MYBBP1A,BICD1,KIAA0754,FAT1,INTS5,HK2,ZFP90,FNBP1L,TBCK,ZBTB24,DMXL2,ASH1L,PCNT,SLC5A5,MMRN2,MYO7A,SMARCA4,TBCCD1,SPATS2,SLC9B2,PIBF1,GBF1,ZSCAN5A,ZC3H13,RIOK2,FARSA,BRE,LYPLAL1,ZNF142,ITGAX,CPSF3,MET,VCL,TSPAN14,GNG5,PHLDB2,ANTXR2,POU2F1,TOR1AIP2,ATP8B2,DKC1,UBR4,WARS,ALAD,ADNP,HNRNPR,WDR73,DISP1,ARC,HEATR1,TMEM101,SMG1,TMCC1,KLHL24,BCKDK,TNIK,SUPT6H,PDE4B,NSUN6,CLSTN2,LETMD1,CHCHD10,PPP1R1C,BMP6,SFI1,MAN1A1,PEX7,SCN1B,STC2,LDLRAD3,PKNOX1,RPS6KB2,KDM6B,SLC6A16,PAQR6,KDM5A,PSMC3IP,PPP1R21,ANKMY2,ZNF324B,SCMH1,MARS,LENG8,ZNF407,NAALADL2,RERE,WDR35,MBD6,MMP16,HRH1 |
| 6.677e-08 | -16.52 | endometrium | COSMIC cancer mutations | endometrium | 16541 | 2177 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,APRT,RBM19,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,TMEM139,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,KLHL23,RNMT,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 7.125e-08 | -16.46 | RPA1 (replication protein A1) | protein interactions | 6117 | 454 | 106 | 16036 | 2270 |
USP7,CUL7,ATRX,RBFOX2,ACTR3,MYH9,HLTF,AP1B1,RPAIN,PELP1,HNRNPA3,KDM1A,PABPC4,BCAS2,ATRIP,RNF2,MSH4,SEH1L,TMPO,SF3A1,PRPF19,RFC4,RFC3,SKIV2L2,LIMA1,RAB7A,HSPA5,WDHD1,VIM,CAV1,BRCA1,MCM2,DSP,RAB10,CHAF1A,SH3GL1,YTHDF2,GEMIN5,SMAD3,DDX3X,DNTTIP1,AHNAK,BRCA2,TP53BP1,HNRNPR,PUS1,FUS,ANXA2,ZNF598,MUTYH,TMEM33,HERC2,MCM6,SCAMP3,FN1,XPC,ZCCHC8,KHDRBS1,UBXN1,RTN4,CSNK1A1,CLINT1,RPS6KA5,RMI1,EIF2S2,ANXA7,LTN1,GTF2H1,ANP32B,POLR1B,GEMIN4,CELF1,FBL,ATP6V0D1,PABPC1,HNRNPM,TERF2,SPTAN1,MTHFD1,MSI2,GTF2H3,APEX1,POLK,RB1CC1,POLA1,TOP3A,LDHA,IMPDH2,SYMPK,POLR2A,UBC,RPA1,ANXA1,TSR1,EPRS,SRBD1,SYNCRIP,MSH3,EIF2S1,ATM,PURB,C7orf50,RBM26,KIAA0196,WDR33,NAPA |
| 7.650e-08 | -16.39 | BENPORATH_SOX2_TARGETS | MSigDB lists | BENPORATH_SOX2_TARGETS | 696 | 138 | 17758 | 2279 |
TRIM16,TMEM109,HLTF,NUP160,UBR5,TRIML2,VPS52,POLE3,AVEN,CDK6,ZNF646,LAMA4,GDAP1,HMBOX1,SLC3A2,ATF4,ARRDC3,NOL6,KIF15,ZSCAN2,LSG1,OSBPL1A,GNAI1,MLLT10,SKIL,TCF7L1,SUFU,BDH2,FIP1L1,VASH2,TNRC6A,EPM2AIP1,FOXO1,JUP,SMG7,ZFP36L1,ZIC2,RSF1,SSR4,ARID1B,SPIRE1,IGF2BP3,SLC7A11,SCAF1,ANP32B,NOC3L,MAP3K12,TIMM8B,KIAA1143,USP49,TLE3,TRA2A,IDH3G,ARID5B,RDH10,CPT1A,NCDN,TCF7L2,RDH11,PWP1,SPAG9,NME7,VCAN,SDCCAG8,USP7,ID1,ZNF516,AMOTL1,RPS29,NDUFB5,RIPK1,RNF24,GBF1,SEMA6A,SLC39A1,FARSA,RRN3,ARMC6,UBR1,SLC38A2,MRPS27,ANO8,CDK12,HN1,PRPF19,SAP30,WDR36,ZCCHC14,POU2F1,VIM,TMEM123,C1orf174,FGFR1,RAD54B,PLIN2,SMAD3,KPNA3,POLR3E,LARGE,H2AFX,DNAJC2,AUH,RFX1,XRRA1,H2AFJ,C14orf159,MYNN,TRIM22,AKT1S1,MLH1,FOXP1,RMI1,MRPS11,PTPN2,NEBL,ARHGAP1,ERRFI1,FBXL19,PNMA1,HSD17B12,FAM98A,APEX1,CRIM1,FGF2,FOXN3,SMARCAD1,ZC4H2,C19orf43,ABCF2,FZD3,UBC,DKK1,POLR3G,ACOX1,SET,TAF12,KAT6A,NIT1 |
| 7.651e-08 | -16.39 | lower_third | COSMIC cancer mutations | lower_third | 8323 | 1184 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,HMOX2,ZNF37A,PDZD2,IKZF5,ZFHX3,THAP4,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,CCDC57,NRAS,EXOC6B,EHMT1,KIF15,WDHD1,ABCC2,SLC9A5,ZNF197,SLC7A1,AHNAK,SSU72,MPV17,DIRAS1,RUNX1,SLC25A26,P2RY11,EPM2AIP1,TMEM63C,TRIO,BTBD9,PDCD7,PITPNM1,RSPRY1,DHX37,WDR60,CCDC88C,PABPC1,PPA1,ANGPT2,MYB,NOM1,RABEPK,KLRD1,STAG1,KCNQ3,TYW1,USP10,MAP7D1,ST6GALNAC3,TRIM37,RDH11,IRS1,DYNC1H1,KPNA1,NME7,TRAP1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,RAB11FIP4,DDR2,ISG20L2,GRINA,ST3GAL6,ZMAT2,RPGRIP1L,ZBED2,ESAM,SPG21,SETD5,WAC,C16orf58,INTS12,MSH4,ZC3H3,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,MEF2D,KCNH3,DSP,VPS53,SLC39A14,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,POLR3E,HOXA3,RPS6KB1,CEP170,CATSPERG,BAG1,MAPT,MORC2,COMMD10,XRRA1,ATG2B,IP6K2,TRIM22,NOP16,UNC13A,ANXA5,LTN1,ZNF710,FBXL19,ACTR3B,SPTAN1,LSM12,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,CCDC150,NSD1,SRCAP,HERC1,ERVMER34-1,BMP4,SORCS2,MTMR1,CYP24A1,CUL7,WDR13,SLC25A21,FAM13A,SCAF8,FRRS1,AMPD3,ECM1,SRSF2,COPS4,ANKRD11,METTL8,TRIML2,ZNF3,SLC25A23,FAM184A,VPS13B,DSC3,FMNL3,MIOS,ANK2,LAMA2,ODC1,CRYBG3,LSG1,BSN,HPRT1,TCF7L1,LSS,CHD3,AHNAK2,ADAM9,PPP3CC,MAGI1,USP15,CLK1,NKD2,FAN1,ARID1B,SPIRE1,CEP290,CTR9,WNT16,LRSAM1,CWF19L2,SNX29,IFT43,OBSCN,MAPK1IP1L,METTL22,GRIK4,CASS4,DTD1,DDX10,SH3PXD2A,USP7,SART1,ID1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,NDUFAF2,NTSR1,RPS29,RIPK1,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PAG1,DDX60L,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,FGGY,ANKRD24,CCDC40,MYH15,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,KIRREL2,VIM,CA5B,EIF3H,ZNF251,EXO1,LMBR1L,ATG7,INTS9,EIF2B3,MUTYH,PARD3,DMGDH,ESCO1,RFX1,RBM19,FOXP1,POGZ,SLC25A20,ADH5,TTC1,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,KRTCAP3,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,POLR3A,DKK1,DSC2,L3MBTL3,TAF4,CSRNP1,BCAS3,FNTB,RBM26,RBPJ,TAF12,NR2F2,XPO6,KIF1B,ZNF292,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,CHD2,CSGALNACT2,SPAG6,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,CAMSAP2,ZDHHC14,SON,DENND4A,DDX60,PLCXD2,GZF1,GNAI1,DOT1L,OSBPL1A,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,HIC2,NRP1,BMI1,SPOCK3,SPOCK2,ZMAT3,NMD3,PRPF38B,JUP,LARS2,PRPF31,DLGAP4,CENPB,MTUS1,TECTA,SLC7A11,NOVA2,LDOC1L,SCAF1,FDFT1,EXOSC2,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,MTR,SLC26A11,ATP9B,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,DPEP1,NCOR1,CNDP2,SMYD3,VMA21,BIRC6,KIAA0232,PTPRG,PABPC1L,IGSF1,BLOC1S2,DECR1,SLX4,ARMC6,LPIN2,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,PREX1,SATB2,MARCH6,MEGF11,ERC1,SNCA,BAZ1A,DNTTIP1,SMARCC1,LARGE,IFT140,SLC4A7,TBXA2R,SETD6,SSH2,BRAF,B4GALT5,FARS2,KIF5C,OPA1,GIGYF2,FAM8A1,PHLDA2,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,FER1L5,SLC40A1,TTLL5,TMEM126B,PACS1,BMS1,GUF1,SLC23A2,RETSAT,INF2,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,IPO4,PIGM,EIF3C,ATRX,RARS2,SLC30A7,DST,CNIH3,MYH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,SRPK2,DTNB,TNK2,DEAF1,FBXW4,SKAP2,ZNF195,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,TIMM44,CCDC3,EIF4ENIF1,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,DCAF5,SCART1,ZCCHC8,VTA1,PCSK7,SMG7,QSER1,EVPL,HVCN1,WDR27,PRF1,ZCCHC7,LRP3,ATP6V0D1,AKAP11,MTHFD1,PPAT,TRA2A,XPO5,ELP3,ZBED4,JMJD1C,ZFP14,EIF2A,CORIN,AGAP1,EXOC6,POP1,SYCP2L,KIAA0355,FSCN1,FAT1,CDKAL1,SLC16A1,PFDN2,TBCK,PDE9A,DMXL2,FEZ2,TNXB,SMARCA4,COBLL1,PIBF1,DHX35,ZC3H13,RRN3,MPHOSPH10,PPFIBP1,SNTG2,ITGAX,VCL,GNG5,MAML3,NARS2,NPW,ANTXR2,PRAME,ATXN1,DKC1,EDEM2,UBR4,ARMC4,IKZF4,DUS3L,HNRNPR,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,RNF130,ARC,NFRKB,BRD9,SMG1,DNAJC2,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,IGF2BP2,ATF7IP,SEMA3E,SOGA1,MFHAS1,GFM2,PIP4K2A,PEX7,SEC24C,STC2,LDLRAD3,ERI3,MICAL3,RPS6KB2,MARCH9,KDM6B,SLC6A16,ARNTL2,DNMBP,CRIM1,PSPC1,SULT4A1,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,ZNF221,DAGLB,SERINC1,WDR35,AGTPBP1,POLR1C,NFKBIB,GNB3,CACNA1H,CSPP1,CHAC1,HLTF,NUP160,SYNJ1,AMBRA1,PCDH7,TOM1L1,C1orf159,SREBF2,NSRP1,SYN2,RABGAP1L,RASSF3,PDS5B,WIZ,ZNF148,AVEN,CNTNAP3B,GNL3,PTPRM,RFX2,AKAP12,MCL1,C10orf76,RBM28,DDX3X,BRCA2,MEF2C,HERC2,EP400,SIRT7,PRAF2,NHS,RSF1,YARS2,SLC39A11,ABCA7,SH2B3,C6orf48,KIAA1671,INTS7,MCM5,CACNB2,ALKBH8,ANP32B,MAP3K12,ZNF518B,COQ3,SERBP1,HMGCR,FADS1,GTF2H3,BDNF,TIMM8B,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,IMPDH2,ONECUT2,MBNL2,CPT1A,NCDN,VPS13C,LRP1B,TASP1,LEMD3,SURF1,ZNF160,WDR33,MB21D2,COG5,SPRED2,ZNF516,ABCA3,TRERF1,BTBD2,ATP6V1A,MYH9,AGAP6,TUBB6,SAFB2,EEA1,RPP30,PRKD3,ABCA12,FMNL1,ATRIP,GARS,KRT7,FAM111B,STAMBP,LGALS1,ARHGEF10,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,TAF2,PES1,IQCH,PAM,WDR7,FUS,ANKS1A,YEATS2,LAMA5,TRIM36,SERINC5,INSIG2,XPC,SESTD1,WDR37,AKT1S1,TGFB2,MBNL1,KRI1,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,FAM98A,ERICH1,ARHGAP39,FRA10AC1,R3HDM2,ZNF467,PDE3B,DDX49,CASC1,BAZ2B,PXDN,NME1-NME2,ARID3B,SLC25A19,SLCO5A1,KDM4C,ANAPC4,BCAS4,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,CSNK2A1,RNF43,TMEM132A,SEC16A,BIRC2,GIT2,ABL2,ARHGAP18,MARVELD2,PPCDC,UBAP2L,RAN,ZNF85,ETV1,PTPRK,TMPO,FLNC,METTL1,CHD9,SLC3A2,ABCC4,SKIV2L2,BAZ2A,KATNAL1,MED27,GMFB,NOL6,ATG12,BRCA1,ZNF91,KIF16B,PEX1,GLS,TOM1L2,TP53BP1,EEFSEC,CCDC146,TECPR2,SOCS4,RAD51B,SGSM2,RNF214,SARS,MCM6,LRRC28,TRIM15,BARX2,RLF,DNAH1,DOPEY1,RNF40,ABCA5,PDE10A,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,CAMKK2,TRAPPC9,LAMC1,TLE3,UTP15,RNH1,WDR25,ZNFX1,MEX3B,SUPT5H,VAC14,NR2F1,PGD,PWP1,NAP1L5,ATXN7,SPAG9,FAM135A,SYNCRIP,PALB2,DNAH17,ZNF430,PPP1R12B,ARHGAP12,TESC,RNF114,NDUFA5,CYLD,RNF24,LPCAT3,ZNF83,KDM1A,CAD,UBR1,FSIP2,ARMC5,ANO8,ZFP37,AKNAD1,CORO1A,CTC1,CASP10,TMEM200A,KAT8,SEC24A,WDR36,EVL,THSD4,SLC35F2,TMEM123,AKAP13,ENC1,USP36,BTBD11,RANBP2,RBBP8,SIX5,PUS1,NFASC,ZNF18,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,CSNK1A1,BZW2,IQGAP2,SACS,ANXA7,IFIT5,PRICKLE2,DDX31,CD44,PCK2,ADAMTSL3,DHX34,TEX14,RAP1GDS1,PEAR1,C11orf49,RHOT2,PIK3CB,ARMC3,NEU1,CENPP,ZRANB3,POLR3G,MKX,TPD52L2,C20orf196,SRBD1,GPC2,ZBTB8OS,SET,ITGB4,RPS6KC1,POLB,MYCBP2,PLRG1,ENAH,AARS,UBR5,GIPR,VPS52,RNF111,FUT11,SEH1L,DDN,DPF3,SLC38A6,SETD1B,ATG9A,NR6A1,NOL8,EYA3,TCEB3,CUX1,SEMA3F,FOXRED1,SH3GL1,HSDL2,VPS13D,GREB1L,DNAH2,FAM118A,SYNPO,ZNF598,PTPN14,EFNB2,WDR75,DROSHA,CELSR1,ZHX3,ANKRD17,OPHN1,PID1,GTF2IRD1,CCDC47,TGFBR2,CD226,IGF2BP3,PRKCE,NAV1,ZNF586,SAMD13,GTF3C3,PRPS1,USE1,SCAF11,SIK3,DDX28,PTPN12,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,UBAP1,ZZEF1,D2HGDH,RIOK3,MAP2K4,ZFHX2,RTTN,PPDPF,TRPM2,LIN28B,URB2,HFM1,NDUFB5,KLHL18,FOSL2,SLC25A44,PDE3A,PHC2,FLAD1,CHD7,ZNF827,UCHL5,NBEA,SERPINH1,PNPLA4,KMT2A,NAA35,ZCCHC14,PDK1,MTIF2,SFXN4,WDPCP,GALK2,MED16,PNN,TBC1D16,STK10,DHX57,VDR,HTR7,YIPF2,ZNF236,H2AFX,ACP1,TRMT2A,ALKBH1,MDN1,PDCD11,NOLC1,NCOR2,CA11,ZNF280C,SLC25A12,MYNN,LIAS,MLH1,IKBKAP,FOXO3,NEDD4,ZNF483,ZNF239,COMMD9,PTRF,NISCH,PMPCA,EXOSC4,LARP4B,C6orf163,TSHZ1,WDFY3,KCNMA1,MMAA,FBXO21,ZDHHC11,HELZ,STX18,MYOM2,PGAM5,BRWD3,STK4,LRRC41,UBN1,NF1,KIF5A,FANCD2,TRPM6,PLOD1,ZNF107,SLC29A1,BCOR,CUTC,AHCYL2,SMARCB1,SRPRB,ZNF804A,RTN1,ANAPC1,LONRF2,THADA,YLPM1,GPR87,ANAPC10,IPP,JOSD1,PCOLCE2,SLC27A5,CCDC121,TRIP13,TIMM50,ZBTB17,TXLNG,CMIP,SLC38A1,CAV1,SOX4,TCTN1,SERGEF,CHAF1A,GEMIN5,TMEM132B,UBTF,GATA6,SUFU,TRMT5,RLTPR,MKL2,GALNT10,COPS6,DMTF1,TNRC6A,SLC12A7,VIPR1,CHST11,FN1,PAX2,MED13L,PHGDH,ETFB,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,CCDC112,NRIP1,N4BP2,POLR1E,CPSF3L,KRT20,RANBP6,PDE4A,TBXAS1,WWC1,C11orf65,PRDM1,C19orf70,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,HK2,EXOC4,KIAA1328,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MYO7A,GBF1,SLC39A1,ZSCAN5A,VPS18,BRE,CAMTA2,SLC38A2,ZNF142,MET,TSPAN14,ZNF460,HTRA2,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PARP2,NLN,ATP8B2,TPK1,ADNP,DISP1,HEATR1,YDJC,KLHL24,DBF4,CLSTN2,CCDC7,MFSD10,MAN1A1,MRPS11,PRKCH,GART,CTNNBL1,TANK,KDELC1,TTC17,DMRT1,MSX1,TEAD1,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,ZNF407,NAPEPLD,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,ZNF330,CUL2,NCBP2,MBD6,TATDN1,PREPL,ZAK,MMP16,ARHGAP27,SLC16A10,HRH1 |
| 7.982e-08 | -16.34 | large_intestine | COSMIC cancer mutations | large_intestine | 17444 | 2264 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,LDOC1L,USPL1,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,TMEM241,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 8.769e-08 | -16.25 | MORF_PRKDC | MSigDB lists | MORF_PRKDC | 187 | 51 | 17758 | 2279 |
MCM6,AK2,DDX18,PRPF31,ANKRD17,KHDRBS1,VARS,XPO7,POM121,PABPC4,CAD,EIF2S2,SREBF2,MCM5,MRPS27,TNPO3,SHMT2,SSBP1,YARS,GNG5,TRIP13,NUDC,RFC4,DEAF1,CAMKK2,GARS,SKIV2L2,NPM3,WDR18,PSMA1,BMS1,MARS,MCM2,DKC1,ABCF1,TARS,ARIH2,POLR2A,CHAF1A,EPRS,CDC16,TRRAP,SMARCC1,HNRNPR,TIMM17A,COQ9,CEBPZ,GPN1,SCARB1,BMI1,XPO6 |
| 9.133e-08 | -16.21 | CUL3 (cullin 3) | protein interactions | 8452 | 1167 | 228 | 16036 | 2270 |
CUL4A,EIF3C,PLRG1,NAT10,PLOD1,SEC16A,NLE1,NUP160,UBR5,PABPC4,SMARCB1,SRPRB,SRSF2,RPS16,COPS4,YLPM1,THADA,UBAP2L,PAK1IP1,IPP,SUCLG2,ME1,SRRM2,SLC25A23,FTSJ3,TRIP13,CARM1,TIMM50,SF3A1,SRPK2,FLNC,SLC3A2,RNMT,KLHL23,SKIV2L2,GNL3,CDK4,HSPA5,SUMO3,DCUN1D5,MTHFD1L,RBM28,YTHDF2,PYCR1,SPOP,GEMIN5,DDX3X,HPRT1,PRPF4,COPS6,BMI1,TNRC6A,USP15,TTN,MCM6,AK2,DROSHA,ZCCHC8,RHOBTB1,PRPF31,KHDRBS1,DPF2,UBXN1,HSD17B10,BTBD9,CCDC47,PRPF39,SSR4,PHGDH,CLINT1,YARS2,IGF2BP3,P3H1,ATXN2,COPS3,ZNF326,IGF2BP1,ALDH18A1,MRPL21,PRMT5,AGL,PABPC1,AKAP11,SERBP1,MTHFD1,MSI2,DDX28,TRA2A,WBSCR22,UTP15,IMPDH2,ARID1A,SUPT5H,PHF6,UBE2E1,POP1,SEC31A,DYNC1H1,PWP1,EPRS,MTHFD2,MYBBP1A,UBAP2,KPNA1,SYNCRIP,NSF,TRAP1,SRP68,SLC16A1,PURB,GPN1,UMPS,SRP14,AGO3,USP7,KCTD7,SART1,NDUFA5,FAM208B,DDX18,BTBD2,ATP6V1A,RBFOX2,KLHL18,PPP2R2A,SMARCA4,RSL1D1,TUBB6,AP1B1,SAFB2,HNRNPA3,HSPA1A,SBDS,NOP56,RPP30,CAD,FARSA,KCTD11,NVL,DNAJB6,PYCRL,ARMC5,IKBKB,MRPS27,SSBP1,PRPF19,SEC24A,PMS1,TUBA1A,DDX41,AKAP8L,CPOX,PCMT1,DLG4,METTL15,VIM,ENC1,NUP214,DSP,ERC1,MAT2A,PUM3,HTR7,PES1,SMARCC1,KPNA3,HNRNPR,DNAJA3,COPS5,FTSJ1,FUS,PDCD11,TROVE2,KLHL24,NIFK,AGO2,FARS2,MYNN,IGF2BP2,VARS,OPA1,IKBKAP,MRPS11,SNW1,GART,SEC24C,NISCH,KDELC1,SHMT2,COPS7B,CPNE7,FBL,LARP4B,YBX3,AMOT,HNRNPM,TOP1,SPTAN1,FAM120B,FAM98A,DDX24,LSM12,PSPC1,ZC3H18,WDR18,LDHA,ARHGEF12,MARS,HIST1H4J,C8orf33,NAALADL2,TARS,UBC,HSPA1B,KLHL22,RARS,TOE1,C20orf196,DDX50,WDR35,HNRNPH3,CUL2,ZRANB2,PGAM5,POLR1C,DDIT3,IPO4,GPATCH4 |
| 9.637e-08 | -16.16 | histone modification | biological process | GO:0016570 | 332 | 78 | 16441 | 2138 |
USP7,ASH1L,TRIM16,KMT2E,BCOR,SIRT2,PRKCA,KDM1A,RING1,KDM2A,KANSL1,WAC,RNF2,KDM5C,POLE3,KMT2A,PRMT3,CARM1,KAT8,BRD4,KMT2D,SETD1B,BAZ2A,SIRT6,EYA3,EHMT1,HDAC8,SETD7,KMT2C,DOT1L,PAF1,TRRAP,BRCA2,HLCS,PER1,BRCC3,SETD6,YEATS2,USP15,HMGA2,EP400,WDR75,TAF1,TCF3,SIRT7,JMJD6,RPS6KA5,CHD5,CDC73,TADA3,RNF40,SUV39H2,CTR9,MED24,FBL,PRMT5,MAP3K12,KDM6B,KDM5B,WDR61,USP49,SMARCAD1,ELP3,SETD2,HIST1H4J,MEN1,TRIM37,UBE2E1,SRCAP,ATXN7,NSD1,EHMT2,ATM,TBL1X,TAF12,SMYD3,KDM4C,KAT6A |
| 1.051e-07 | -16.07 | regulation of macromolecule biosynthetic process | biological process | GO:0010556 | 3904 | 605 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,TOM1L1,SREBF2,ZFHX3,IKZF5,WIZ,ZNF148,FNIP2,KDM5C,HMBOX1,EIF4E3,GNL3,EHMT1,NFIA,KRBOX4,RFX2,ZNF197,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,EPM2AIP1,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ABCA7,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,RPS6KB1,FUS,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,TGFB2,ZNF691,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,UQCC1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ZNF124,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ETF1,ZFP37,RNF2,PRMT3,CTC1,SEC24A,KAT8,KDM3B,PCGF3,DDX41,ENC1,ZNF251,PUM3,EIF3H,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,EIF2B3,ZNF589,PKIB,ZNF507,ESCO1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,SELT,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,HIST1H4J,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,FNTB,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,GABPB2,AARS,MGA,LPIN1,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,LSM14A,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,LARS2,ZHX3,ANKRD17,CENPB,PID1,GTF2IRD1,CHD5,IGF2BP3,HR,ZNF586,MYC,IGF2BP1,TERF2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,EPRS,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,PAIP2,TERF2IP,CHD7,ZNF827,KDM2A,SHC1,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,MTIF2,SATB2,MED16,PNN,SETD7,SERP1,ERC1,ZBTB25,SNCA,BAZ1A,VDR,MSX2,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,GIGYF2,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,ERRFI1,LARP4B,YBX3,MBTPS2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,IREB2,BRWD3,DDIT3,KAT6A,ZNF76,EIF3C,UBN1,KMT2E,ATRX,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,ZBTB17,DEAF1,TRIM13,TXLNG,ZNF195,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,IGF2BP2,MED18,BMP6,PRKCH,HAS3,UTS2,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,EIF5B,CTIF,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,NFKBIB |
| 1.094e-07 | -16.03 | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN | 81 | 29 | 17758 | 2279 |
DNAJC2,PCNT,SKAP2,RB1CC1,TEAD1,PTPRM,SMAD7,ARHGEF10,ATXN1,WDHD1,WDR37,GALK2,SON,CTIF,DST,BICD1,ZFHX3,PVRL3,MSH3,MAD1L1,CTAGE5,PDS5B,KIAA0922,SYNJ2,TOP1,TMCC1,NAV3,USP15,VPS13B |
| 1.193e-07 | -15.94 | REGULATION_OF_TRANSCRIPTION | MSigDB lists | REGULATION_OF_TRANSCRIPTION | 558 | 115 | 17758 | 2279 |
TCF12,ZNF254,ZNF76,ID1,TRERF1,UBN1,NPAS2,ATRX,RBFOX2,PPARGC1B,PBX1,BCOR,SIRT2,FOSL2,GABPB2,IGSF1,MAP2K3,SMARCB1,NRF1,SREBF2,ZFHX3,PHF5A,JAZF1,IKBKB,ZEB1,ZNF148,CHD2,HCFC2,CARM1,MAML3,KAT8,ATF4,TFCP2,NR6A1,PPARG,MED27,TCEB3,CUX1,POU2F1,ATXN1,HDAC8,BRCA1,ERC1,UBTF,VDR,SMAD3,DYRK1B,RBBP8,SUPT4H1,SUFU,GATA6,SMARCC1,ELP2,CHD3,PER1,KLF4,MKL2,ARNTL,PQBP1,TNFRSF1A,RUNX1,MED20,HMGA2,EGR1,FOXO1,ZHX3,MAP3K13,KHDRBS1,TCF3,TRAK1,NFX1,ID2,ATF7IP,RSF1,TRIM22,IKBKAP,RPS6KA5,FOXO3,BMP6,TADA3,ABL1,SNW1,SUB1,PSMG4,ZNF354A,VPS72,MYC,BUD31,GTF2H1,TIMELESS,NRIP1,CAMKK2,RREB1,KDM5B,FOXN3,KDM5A,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,MEN1,SUPT5H,TCF7L2,POLR3G,SRCAP,NSD1,MYBBP1A,HIF1A,TBX3,RBPJ,NR2F2,DDIT3,KAT6A |
| 1.199e-07 | -15.94 | WD40/YVTN_repeat-like_dom | interpro domains | IPR015943 | 327 | 76 | 18293 | 2341 |
DMXL2,GNB3,BIRC6,PAFAH1B1,WDR74,WDR13,PLRG1,PPP2R2A,NUP43,CORO6,NBEAL1,DENND3,NLE1,SEMA6A,PLXNB1,AMBRA1,NUP133,NBEA,PAK1IP1,CORO1A,MET,UTP4,SEH1L,LYST,PRPF19,WDR36,FBXW4,MIOS,ARHGEF10,WDHD1,SEMA3F,MED16,NUP214,GEMIN5,WDR5B,ELP2,WDR73,TECPR2,TSSC1,WDR7,IFT140,SEMA3C,PRPF4,WDR66,DCAF5,WDR75,PIK3R4,MAPK8IP3,WDR26,WDR37,SEMA3E,PEX7,WDR27,SEMA3D,WDR60,WDR61,WDFY3,TLE3,WDR18,UTP15,WDR25,EIF2A,PWP1,SEC31A,SPAG9,NOL10,PALB2,WDR35,HERC1,BCAS3,TBL1X,APAF1,WDR33,BRWD3,CORO2B,ANAPC4 |
| 1.234e-07 | -15.91 | TOOKER_GEMCITABINE_RESISTANCE_UP | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_UP | 77 | 28 | 17758 | 2279 |
ACSL5,ZNF292,DSC3,FGF9,WDR74,ITPA,CPOX,ARID5B,PDE4B,ARFIP2,RNH1,ABCC2,TRIM22,PALLD,ODC1,ISG15,TCF7L2,CIAPIN1,ANXA1,ZFAND3,RPL28,ERVMER34-1,BDH2,BMP4,CCNB1IP1,PEG10,TOMM34,MEF2C |
| 1.264e-07 | -15.88 | MODULE_133 | MSigDB lists | MODULE_133 | 15 | 11 | 17758 | 2279 |
CARS,FARSA,EPRS,SARS,GARS,NARS,HARS,VARS,YARS,AARS,TARS |
| 1.264e-07 | -15.88 | MODULE_160 | MSigDB lists | MODULE_160 | 15 | 11 | 17758 | 2279 |
CARS,EPRS,SARS,GARS,NARS,HARS,HARS2,VARS,YARS,AARS,TARS |
| 1.269e-07 | -15.88 | MITSIADES_RESPONSE_TO_APLIDIN_UP | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_UP | 408 | 90 | 17758 | 2279 |
POLB,SPRED2,ASCC1,FEM1C,DDX18,DDX19A,NECAP1,FAM13A,DENND3,MAP2K3,RPGRIP1L,GIPR,TERF2IP,IDI1,BCAS2,SOCS1,JOSD1,ETV1,ZCCHC14,SLC3A2,AKAP8L,ATG9A,LIMA1,ATG12,ATP6V0A1,MCL1,DENND4A,ST3GAL5,USP36,TJAP1,SPOP,PLIN2,VDR,SMAD3,KLF4,PRPF4,ARC,RUNX1,DMTF1,NCOR2,IFT57,FOXO1,MAP3K13,CLK1,ZCCHC8,SUPT6H,ID2,WDR26,ATF7IP,JMJD6,IP6K2,C1orf50,MTUS1,NAMPT,C6orf48,CLDND1,TTC17,MAP3K14,POLR1E,TOMM34,KDM6B,PEA15,SIK3,IFRD1,BDNF,PDE4A,TLE3,ARID5B,TYW1,TPM4,HIST1H4J,OASL,KLF6,PDE3B,POLR2A,HERPUD1,DDX50,GADD45A,KIAA0355,ARID3B,ORC5,RIOK3,ZCCHC6,USP20,PEX13,PFDN2,TESC,DDIT3,N4BP2L2,RNF114 |
| 1.280e-07 | -15.87 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 1157 | 208 | 17775 | 2278 |
ARHGAP26,ZNF292,IMMP2L,CGN,LYRM4,CNTNAP3,FANCD2,SLC25A21,CSNK2A1,SBF2,ENAH,FAM13A,NUP160,LRP5L,NOS1AP,PCDH7,ZNF804A,DST,ANAPC1,ECM1,PDZD2,SYN2,RABGAP1L,JAZF1,HKR1,ANAPC10,MAD1L1,PPCDC,ZEB1,SUCLG2,CDK6,TRIP13,CEP128,SRPK2,PTPRK,DTNB,CCDC57,DPF3,NRAS,OSBP2,ABCC4,ANK2,PACRGL,KSR2,WDHD1,LAMA2,ZDHHC14,LSG1,TAF9B,GNAI1,TMEM132B,DDX3X,LSS,EIF4ENIF1,SUFU,HLCS,GATA6,DNAJC1,TECPR2,CRCP,CSMD3,RNF214,SPOCK3,SPOCK2,TNRC6A,SLC12A7,CELSR1,RHOBTB1,OPHN1,MED13L,LYRM2,PARN,MTUS1,IGF2BP3,RBM20,KIAA1958,SIPA1L3,MCAM,KIAA1671,GMDS,PPA1,AKAP11,HMGCR,BDNF,STAG1,KCNQ3,PRDM16,XPO5,ARID5B,RAPGEF4,RYR2,OBSCN,TTYH2,ST6GALNAC3,CORIN,PLCB1,EVI5,AGAP1,VAC14,EXOC6,ATP9B,ASCC3,VPS13C,LRP1B,BICD1,SYNCRIP,DNAH17,EXOC4,SNX24,CDKAL1,SIL1,DTD1,C7orf50,DDX10,SMYD3,COG5,PTCD2,SYT17,SMARCA4,PTPRG,LCLAT1,EEA1,CAD,PYCRL,FMNL1,GLYR1,SNTG2,NBEA,FHIT,TMEM120B,ZC3H3,MOSPD1,PMS1,ANTXR2,KMT2D,THSD4,WDPCP,SLCO6A1,GRHL3,PCNXL2,VPS53,TPK1,BTBD11,RAD54B,FBXL5,HTR7,KDM4B,KPNA3,ASTN2,ZNF333,TSSC1,IFT140,KLHDC4,EIF2B3,XRCC4,SMG1,PARD3,BRAF,XRRA1,CMTM8,PDE4B,C1orf226,CLSTN2,FARS2,MON2,FOXP1,RSRC1,BMP6,ANKRD54,IQGAP2,CTNNBL1,TMEM161A,UNC13A,DSG2,PMPCA,GREB1,DYNC2H1,CPNE7,LDLRAD3,SAMD4A,SOX6,DIS3L2,FER1L5,TMC7,DNMBP,FGF2,ANKMY2,SCFD2,NXN,RAP1GDS1,PEAR1,ARHGAP32,MEN1,PALLD,PDE3B,ZNF407,EIF5B,NAALADL2,CHCHD6,ZNF708,TRIB3,MPP7,CSRNP1,BCAS3,GLG1,MYOM2,SORCS2,ADK |
| 1.340e-07 | -15.83 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 985 | 182 | 17758 | 2279 |
SLC37A3,PRKAB2,TMEM109,ADAMTS6,TMEM132A,BIRC2,MRPS30,PCDH7,ABL2,MMP7,NEK6,ZFHX3,PMAIP1,CNIH3,MARVELD2,JAZF1,GPR87,FUT11,HCFC2,PPM1K,TRIM14,DEAF1,GCNT2,LIMA1,RNMT,ARRDC3,HSPA5,ATG12,MCL1,DCUN1D5,PITPNB,DDX60,RHOU,MSRA,LSS,GATA6,AHNAK2,FIS1,PPP3CC,DLX2,NRP1,TPM1,DCAF5,USP15,FN1,EGR1,FOXO1,SEC24D,ZFP36L1,TGFBR2,RLF,DDIT4,NAMPT,FKBP1A,PRKCE,SUB1,SIPA1L3,ZNF586,TSPAN2,ABCA5,SEMA3D,WDR60,CCDC167,NT5E,PEA15,BDNF,ARID5B,ZNFX1,ARRDC4,ANGPTL4,HERPUD1,DAGLA,MGAT2,MYBBP1A,SPAG9,C6orf141,FGFBP1,HK2,TMEM117,PTP4A2,SMYD3,RNF114,CYLD,PAPD4,PAFAH1B1,ATP6V1A,SLC2A1,ACTR3,COBLL1,SPATS2L,PLEK2,ST3GAL6,DENND3,TNKS1BP1,ZNF121,DDX60L,FDX1,SOCS1,DNAJB6,CLCN6,RNF2,PXK,MGLL,TMEM14C,PLEKHA4,LYST,MOSPD1,HN1,PHLDB2,ARHGAP17,MALL,WDR36,PTBP2,PDK1,LRRC8A,TOR1AIP2,ARL5B,SERP1,WARS,DCBLD2,ARHGAP21,COPS5,KLF4,PAM,SCARB1,ANXA2,XRCC4,PKIB,TMCC1,COMMD10,HMGA2,TNIK,INSIG2,MAP3K13,B4GALT5,ID2,RCAN1,WDR26,TRIM22,GAS6,BHLHE40,PHLDA2,PSMF1,GFM2,PIP4K2A,MAN1A1,PVRL3,IFIT5,TANK,STC2,ANXA5,SELT,MAP3K14,CD44,ERRFI1,PFKFB4,POLK,ZNF654,USP42,ARHGAP39,LDHA,FERMT2,IL6R,OASL,KLF6,MMAA,PIK3CB,MKX,ANXA1,OXSR1,RETSAT,GADD45A,GLG1,EIF2S1,RBPJ,NR2F2,SORCS2,RPS6KC1,RABEP1,KIF1B,DDIT3,KDM4C |
| 1.347e-07 | -15.82 | acute_myeloid_leukaemia | COSMIC cancer mutations | acute_myeloid_leukaemia | 10922 | 1511 | 17775 | 2278 |
ARHGAP26,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,CIAPIN1,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,AP1M1,MAD1L1,SRRM2,ZNRD1,FTSJ3,PPM1K,CCDC57,NRAS,RNMT,KLHL23,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,WDHD1,ABCC2,ZNF197,AHNAK,LRRC40,SYNGR2,BDH2,MPV17,RUNX1,TPM1,VASH2,SLC25A26,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,PITPNM1,CHN1,RBM20,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,GSTO2,NME7,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,RAB11FIP4,GTF2H2C,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,RPGRIP1L,NDUFB3,CD96,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,MSH4,MGLL,TRMT12,ZC3H3,DENND1A,LYST,KMT2D,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,FBXL5,ARHGAP21,KDM4B,ASTN2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,CEP170,CATSPERG,MORC2,COMMD10,SHQ1,XRRA1,ATG2B,TRIM22,PSMF1,TTLL11,TAF3,CFDP1,UNC13A,ACOT11,LTN1,RAPGEFL1,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,VPS37A,DDX24,LSM12,ZC3H18,NXN,CCDC113,PPIP5K2,CCDC150,OXSR1,NSD1,SRCAP,HERC1,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,SLC25A21,FAM13A,SCAF8,FRRS1,MAP2K3,AMPD3,SRSF2,PHF5A,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,PPARG,ANK2,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,CXADR,BSN,DYRK1B,TCF7L1,INSIG1,CHD3,E2F4,AHNAK2,DPP4,ADAM9,PRPF4,TSEN2,MAGI1,USP15,CTU2,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ARID1B,RNFT2,MLX,CEP290,VPS72,NDRG4,CTR9,PNPLA3,CWF19L2,SNX29,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,SNX24,CASS4,SIL1,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,OLFM2,PAPD4,SUCLG1,ARID2,OSBPL9,NTSR1,SLC2A1,LAGE3,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,PAG1,DDX60L,URB1,PLXNB1,FDX1,ANKRD13A,NRF1,IDI1,JAG1,NUP133,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,ARHGAP17,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,CA5B,NHSL1,TJAP1,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,FAHD1,MUTYH,PARD3,DMGDH,ESCO1,VARS,RBM19,FOXP1,POGZ,SLC25A20,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,SMARCAD1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,SMPDL3B,POLR3A,DKK1,CDH24,NOL10,DSC2,CSRNP1,BCAS3,FNTB,USP20,TMEM219,XPO6,KIF1B,C6orf223,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,EFHC1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,SH3RF1,CCNT1,NSMCE1,ARL6IP5,LUC7L3,HIC2,NRP1,WDR66,BLMH,SPOCK3,SPOCK2,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,TATDN3,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,PABPC1L,FLNB,IGSF1,SLX4,ASNS,ARMC6,PPID,LPIN2,DTNBP1,TTC3,CMPK1,CDK12,CASP8AP2,GON4L,C1orf228,PREX1,LRRC8A,SATB2,MARCH6,MEGF11,SETD7,SERP1,BAZ1A,MSX2,CAMK2D,SMARCC1,G6PD,IFT140,SLC4A7,CBWD1,XRCC4,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,RCAN1,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,NAV3,TMC7,FER1L5,SLC40A1,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,PACS1,BMS1,KLF6,GUF1,SLC23A2,RETSAT,DDX50,ZNF155,IREB2,ORC5,ATM,SVIL,ADK,DDIT3,IPO4,IMMP2L,ZNF76,LETM1,EIF3C,ATRX,RARS2,SLC30A7,DST,CNIH3,JAZF1,SLC39A7,MYH3,GPATCH1,B3GNTL1,KIAA0922,HCFC2,YARS,CEP128,DTNB,DEAF1,SESN2,SKAP2,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,PITPNB,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,EME1,ZC3H8,DCAF5,MTCH1,RHOBTB1,ZCCHC8,STXBP6,PCSK7,SMG7,QSER1,EVPL,ELL,ZNF354A,WDR27,ISPD,CCDC124,PRF1,ZCCHC7,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,HBG2,PPAT,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,TBL1X,TBCK,PDE9A,TCF12,DMXL2,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ITGAX,VCL,C6orf89,MAML3,NARS2,ANTXR2,PRAME,METTL2A,GRHL3,ATXN1,METTL15,EDEM2,UBR4,S100A16,BATF3,ARMC4,IKZF4,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,SEMA3E,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,KDM6B,SLC6A16,DNMBP,GPHN,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,WDR35,ANKRD30BL,VPS37B,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,NOS1AP,PCDH7,TOM1L1,C1orf159,NEK6,SREBF2,NSRP1,SYN2,PMAIP1,RABGAP1L,FAAH2,RASSF3,PDS5B,ZNF148,LYRM5,HRG,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,WLS,GNL3,RFX2,AKAP12,PLEKHM3,DCUN1D5,C10orf76,RBM28,STOML2,DLEU1,DDX3X,BRCA2,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,ABCA7,SLC39A11,SH2B3,DDX56,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,NOC3L,CALN1,AGL,MAP3K12,ZNF518B,COQ3,FMNL2,SERBP1,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,CPT1A,ONECUT2,EVI5,ABCF1,ZNF655,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,PRKD3,ABCA12,ERI1,PYCRL,ATRIP,GSTA4,CEP63,TMEM136,LSM10,GARS,KRT7,FAM111B,ARHGEF10,ADAM32,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,XPC,SESTD1,TRAK1,ID2,SF3A3,WDR37,AKT1S1,RSRC1,MBNL1,POM121,KRI1,TADA3,TMSB10,ARHGAP1,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,FAM98A,FGF9,ERICH1,CLYBL,ARHGAP39,FRA10AC1,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,SLCO5A1,SLC25A19,PSAP,GPAM,DOCK6,CORO2B,KDM4C,ANAPC4,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,TMEM132A,SEC16A,COX10,GIT2,ABL2,ARHGAP18,DHX33,MARVELD2,TRMU,UBAP2L,RAN,ETV1,SF3A1,PTPRK,CDC37,FLNC,CHD9,GCNT2,ABCC4,HARS,BAZ2A,GDPD1,MED27,NOL6,ATG12,BRCA1,ZNF91,MGST1,KIF16B,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,OXNAD1,MCM6,STX8,LRRC28,TRIM15,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,SYNJ2,GMDS,ALDH18A1,NAA38,TRAPPC9,LAMC1,CRADD,TLE3,UTP15,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,VAC14,NR2F1,PGD,ATXN7,ITPRIPL1,FAM135A,SYNCRIP,PALB2,DNAH17,TBPL1,PPP1R12B,NAPA,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RSL1D1,LPCAT3,ZNF83,PELP1,KDM1A,CAD,DUS4L,UBR1,FSIP2,DNAJB6,CYB5D1,C15orf40,HIRIP3,ETF1,HIBCH,ANO8,ZFP37,CORO1A,AKNAD1,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,GLTSCR2,THSD4,CPOX,SLC35F2,AKAP13,ENC1,NUP214,USP36,BTBD11,SMAD3,RANBP2,ZNF333,TIMM17A,CLEC16A,ITGA2,ZNF436,TSSC1,PUS1,ZNF18,NFASC,AP2S1,ZNF589,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,ARFIP2,C14orf159,C15orf57,ZNF594,IQGAP2,NDUFV1,SACS,ZNF561,CWC27,PRICKLE2,HIST2H3D,GREB1,SELT,CD44,PCK2,HSD17B12,ADAMTSL3,ZNF654,ZMYM5,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,GPNMB,TMEM175,PIK3CB,ARMC3,MKX,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ADAT2,MSH3,GLG1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,GCSH,MYCBP2,CGN,PRDX6,PRKAB2,PLRG1,ENAH,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,ME1,CEP135,MEIS3,SEH1L,TBC1D8,DDN,DPF3,SLC38A6,SETD1B,NR6A1,ALDH1L2,NOL8,CUX1,SEMA3F,SAP30BP,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,USE1,SCAF11,SIK3,SYNGAP1,SIGMAR1,POLA1,AOC2,KIAA0586,PTPN12,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,UMPS,IQSEC2,MACROD1,ZFHX2,RTTN,PPDPF,PTCD2,TBKBP1,AMOTL1,TRPM2,SPATA2L,URB2,RIBC2,HFM1,OLA1,KLHL18,SPATS2L,AP1B1,TRIM66,PDE3A,PHC2,CHD7,ZNF827,PUS3,SHC1,KDM2A,NBEA,SSBP1,KMT2A,PLEKHA4,NAA35,RFC4,ZCCHC14,RFC3,MPP6,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,TBC1D16,STK10,DHX57,DCBLD2,HTR7,DNAJA3,ZNF236,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,NCOR2,UTP14A,TTC27,C10orf2,ZNF280C,NFX1,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,NEDD4,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,PMPCA,UPF2,RDX,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,MMAA,NOP58,ECH1,YIF1A,FBXO21,ZDHHC11,HELZ,STX18,MYOM2,BRWD3,SLC43A1,STK4,LRRC41,SLC37A3,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,ZNF107,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,RTN1,ZNF804A,ANAPC1,YLPM1,THADA,LONRF2,ZNHIT6,ANAPC10,RELB,JOSD1,POLR3B,SLC27A5,NDUFA6,OGG1,LONP1,ZBTB17,LAMA4,TXLNG,ZNF680,CMIP,SLC38A1,LVRN,GPCPD1,SOX4,ZSCAN2,TCTN1,CDHR3,PAF1,RHOU,TMEM132B,GATA6,TRMT5,RLTPR,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,C11orf54,RHBDD1,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,NRIP1,N4BP2,CPSF3L,VOPP1,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,KIAA1328,TMEM182,PDSS2,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,ZSCAN5A,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,HTRA2,MOSPD1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,PARP2,NLN,R3HDM1,ATP8B2,C1orf174,TPK1,RAD54B,ZC3H12A,ADNP,SLC25A11,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,NBR2,SULT1C2,SH2D3A,DBF4,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,KDELC1,SHMT2,TTC17,UTS2,AMOT,PAQR6,MSX1,TEAD1,ANKMY2,PPP1R21,PHACTR2,ARHGAP32,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,MBD6,TATDN1,PREPL,MMP16,ZAK,SLC16A10 |
| 1.347e-07 | -15.82 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | 10922 | 1511 | 17775 | 2278 |
ARHGAP26,ADAM19,CDCP1,THOC5,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,CIAPIN1,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,AP1M1,MAD1L1,SRRM2,ZNRD1,FTSJ3,PPM1K,CCDC57,NRAS,RNMT,KLHL23,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,WDHD1,ABCC2,ZNF197,AHNAK,LRRC40,SYNGR2,BDH2,MPV17,RUNX1,TPM1,VASH2,SLC25A26,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,PITPNM1,CHN1,RBM20,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,GSTO2,NME7,EHMT2,TRAP1,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,RAB11FIP4,GTF2H2C,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,RPGRIP1L,NDUFB3,CD96,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,MSH4,MGLL,TRMT12,ZC3H3,DENND1A,LYST,KMT2D,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,FBXL5,ARHGAP21,KDM4B,ASTN2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,CEP170,CATSPERG,MORC2,COMMD10,SHQ1,XRRA1,ATG2B,TRIM22,PSMF1,TTLL11,TAF3,CFDP1,UNC13A,ACOT11,LTN1,RAPGEFL1,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,VPS37A,DDX24,LSM12,ZC3H18,NXN,CCDC113,PPIP5K2,CCDC150,OXSR1,NSD1,SRCAP,HERC1,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,SLC25A21,FAM13A,SCAF8,FRRS1,MAP2K3,AMPD3,SRSF2,PHF5A,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,PPARG,ANK2,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,CXADR,BSN,DYRK1B,TCF7L1,INSIG1,CHD3,E2F4,AHNAK2,DPP4,ADAM9,PRPF4,TSEN2,MAGI1,USP15,CTU2,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ARID1B,RNFT2,MLX,CEP290,VPS72,NDRG4,CTR9,PNPLA3,CWF19L2,SNX29,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,SNX24,CASS4,SIL1,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,OLFM2,PAPD4,SUCLG1,ARID2,OSBPL9,NTSR1,SLC2A1,LAGE3,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,PAG1,DDX60L,URB1,PLXNB1,FDX1,ANKRD13A,NRF1,IDI1,JAG1,NUP133,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,ARHGAP17,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,CA5B,NHSL1,TJAP1,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,FAHD1,MUTYH,PARD3,DMGDH,ESCO1,VARS,RBM19,FOXP1,POGZ,SLC25A20,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,SMARCAD1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,SMPDL3B,POLR3A,DKK1,CDH24,NOL10,DSC2,CSRNP1,BCAS3,FNTB,USP20,TMEM219,XPO6,KIF1B,C6orf223,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,EFHC1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,SH3RF1,CCNT1,NSMCE1,ARL6IP5,LUC7L3,HIC2,NRP1,WDR66,BLMH,SPOCK3,SPOCK2,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,TATDN3,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,PABPC1L,FLNB,IGSF1,SLX4,ASNS,ARMC6,PPID,LPIN2,DTNBP1,TTC3,CMPK1,CDK12,CASP8AP2,GON4L,C1orf228,PREX1,LRRC8A,SATB2,MARCH6,MEGF11,SETD7,SERP1,BAZ1A,MSX2,CAMK2D,SMARCC1,G6PD,IFT140,SLC4A7,CBWD1,XRCC4,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,RCAN1,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,NAV3,TMC7,FER1L5,SLC40A1,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,PACS1,BMS1,KLF6,GUF1,SLC23A2,RETSAT,DDX50,ZNF155,IREB2,ORC5,ATM,SVIL,ADK,DDIT3,IPO4,IMMP2L,ZNF76,LETM1,EIF3C,ATRX,RARS2,SLC30A7,DST,CNIH3,JAZF1,SLC39A7,MYH3,GPATCH1,B3GNTL1,KIAA0922,HCFC2,YARS,CEP128,DTNB,DEAF1,SESN2,SKAP2,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,PITPNB,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,EME1,ZC3H8,DCAF5,MTCH1,RHOBTB1,ZCCHC8,STXBP6,PCSK7,SMG7,QSER1,EVPL,ELL,ZNF354A,WDR27,ISPD,CCDC124,PRF1,ZCCHC7,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,HBG2,PPAT,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,TBL1X,TBCK,PDE9A,TCF12,DMXL2,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,COBLL1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,ZC3H13,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ITGAX,VCL,C6orf89,MAML3,NARS2,ANTXR2,PRAME,METTL2A,GRHL3,ATXN1,METTL15,EDEM2,UBR4,S100A16,BATF3,ARMC4,IKZF4,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,DYM,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,SEMA3E,PIP4K2A,BMP6,GFM2,PEX7,SEC24C,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,TOP1,RPS6KB2,KDM6B,SLC6A16,DNMBP,GPHN,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,WDR35,ANKRD30BL,VPS37B,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,NOS1AP,PCDH7,TOM1L1,C1orf159,NEK6,SREBF2,NSRP1,SYN2,PMAIP1,RABGAP1L,FAAH2,RASSF3,PDS5B,ZNF148,LYRM5,HRG,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,WLS,GNL3,RFX2,AKAP12,PLEKHM3,DCUN1D5,C10orf76,RBM28,STOML2,DLEU1,DDX3X,BRCA2,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,NHS,PLA2G12A,RSF1,CLINT1,SLC1A1,ABCA7,SLC39A11,SH2B3,DDX56,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,NOC3L,CALN1,AGL,MAP3K12,ZNF518B,COQ3,FMNL2,SERBP1,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,CPT1A,ONECUT2,EVI5,ABCF1,ZNF655,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,BTBD2,PDK4,ACTR3,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,PRKD3,ABCA12,ERI1,PYCRL,ATRIP,GSTA4,CEP63,TMEM136,LSM10,GARS,KRT7,FAM111B,ARHGEF10,ADAM32,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,XPC,SESTD1,TRAK1,ID2,SF3A3,WDR37,AKT1S1,RSRC1,MBNL1,POM121,KRI1,TADA3,TMSB10,ARHGAP1,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,FAM98A,FGF9,ERICH1,CLYBL,ARHGAP39,FRA10AC1,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,RARS,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,SLCO5A1,SLC25A19,PSAP,GPAM,DOCK6,CORO2B,KDM4C,ANAPC4,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,TMEM132A,SEC16A,COX10,GIT2,ABL2,ARHGAP18,DHX33,MARVELD2,TRMU,UBAP2L,RAN,ETV1,SF3A1,PTPRK,CDC37,FLNC,CHD9,GCNT2,ABCC4,HARS,BAZ2A,GDPD1,MED27,NOL6,ATG12,BRCA1,ZNF91,MGST1,KIF16B,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,OXNAD1,MCM6,STX8,LRRC28,TRIM15,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,SYNJ2,GMDS,ALDH18A1,NAA38,TRAPPC9,LAMC1,CRADD,TLE3,UTP15,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,VAC14,NR2F1,PGD,ATXN7,ITPRIPL1,FAM135A,SYNCRIP,PALB2,DNAH17,TBPL1,PPP1R12B,NAPA,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RSL1D1,LPCAT3,ZNF83,PELP1,KDM1A,CAD,DUS4L,UBR1,FSIP2,DNAJB6,CYB5D1,C15orf40,HIRIP3,ETF1,HIBCH,ANO8,ZFP37,CORO1A,AKNAD1,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,GLTSCR2,THSD4,CPOX,SLC35F2,AKAP13,ENC1,NUP214,USP36,BTBD11,SMAD3,RANBP2,ZNF333,TIMM17A,CLEC16A,ITGA2,ZNF436,TSSC1,PUS1,ZNF18,NFASC,AP2S1,ZNF589,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,ARFIP2,C14orf159,C15orf57,ZNF594,IQGAP2,NDUFV1,SACS,ZNF561,CWC27,PRICKLE2,HIST2H3D,GREB1,SELT,CD44,PCK2,HSD17B12,ADAMTSL3,ZNF654,ZMYM5,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,GPNMB,TMEM175,PIK3CB,ARMC3,MKX,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ADAT2,MSH3,GLG1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,GCSH,MYCBP2,CGN,PRDX6,PRKAB2,PLRG1,ENAH,UBR5,MGA,GIPR,RPS16,PAK1IP1,RNF111,ME1,CEP135,MEIS3,SEH1L,TBC1D8,DDN,DPF3,SLC38A6,SETD1B,NR6A1,ALDH1L2,NOL8,CUX1,SEMA3F,SAP30BP,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,USE1,SCAF11,SIK3,SYNGAP1,SIGMAR1,POLA1,AOC2,KIAA0586,PTPN12,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,UMPS,IQSEC2,MACROD1,ZFHX2,RTTN,PPDPF,PTCD2,TBKBP1,AMOTL1,TRPM2,SPATA2L,URB2,RIBC2,HFM1,OLA1,KLHL18,SPATS2L,AP1B1,TRIM66,PDE3A,PHC2,CHD7,ZNF827,PUS3,SHC1,KDM2A,NBEA,SSBP1,KMT2A,PLEKHA4,NAA35,RFC4,ZCCHC14,RFC3,MPP6,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,TBC1D16,STK10,DHX57,DCBLD2,HTR7,DNAJA3,ZNF236,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,NCOR2,UTP14A,TTC27,C10orf2,ZNF280C,NFX1,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,NEDD4,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,PMPCA,UPF2,RDX,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,TSHZ1,WDFY3,KCNMA1,WDR18,TBRG4,MMAA,NOP58,ECH1,YIF1A,FBXO21,ZDHHC11,HELZ,STX18,MYOM2,BRWD3,SLC43A1,STK4,LRRC41,SLC37A3,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,ZNF107,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,EDC3,SMARCB1,RTN1,ZNF804A,ANAPC1,YLPM1,THADA,LONRF2,ZNHIT6,ANAPC10,RELB,JOSD1,POLR3B,SLC27A5,NDUFA6,OGG1,LONP1,ZBTB17,LAMA4,TXLNG,ZNF680,CMIP,SLC38A1,LVRN,GPCPD1,SOX4,ZSCAN2,TCTN1,CDHR3,PAF1,RHOU,TMEM132B,GATA6,TRMT5,RLTPR,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,C11orf54,RHBDD1,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,NRIP1,N4BP2,CPSF3L,VOPP1,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,KIAA1328,TMEM182,PDSS2,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,ZSCAN5A,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,HTRA2,MOSPD1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,PARP2,NLN,R3HDM1,ATP8B2,C1orf174,TPK1,RAD54B,ZC3H12A,ADNP,SLC25A11,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,NBR2,SULT1C2,SH2D3A,DBF4,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,KDELC1,SHMT2,TTC17,UTS2,AMOT,PAQR6,MSX1,TEAD1,ANKMY2,PPP1R21,PHACTR2,ARHGAP32,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,MBD6,TATDN1,PREPL,MMP16,ZAK,SLC16A10 |
| 1.405e-07 | -15.78 | single-organism organelle organization | biological process | GO:1902589 | 2192 | 363 | 16441 | 2138 |
ARHGAP26,CGN,ACTG1,MRPL10,AARS2,MKS1,TUBE1,ENAH,PRKCA,RAC3,AMBRA1,NEK6,PMAIP1,MAD1L1,PDS5B,KDM5C,CEP135,SEH1L,GDAP1,DPF3,SETD1B,ATG9A,LIMA1,EYA3,EHMT1,KIF15,WDHD1,CAMSAP2,SON,TMSB4X,STOML2,DOT1L,TRRAP,RBSN,BRCA2,FIS1,TPM1,CCNB1IP1,WDR75,EP400,IFT57,CDC42EP2,JUP,SIRT7,OPHN1,PIK3R4,PID1,CDC73,CHD5,YARS2,NAV1,MED24,PRMT5,MRPL21,MAP3K12,FMNL2,CAV2,TERF2,STAG1,PRIM2,ANAPC13,WDR61,POLA1,KIAA0586,SMARCD3,MAP7D1,SNAP25,ARID1A,TRIM37,ONECUT2,DYNC1H1,SEC31A,NME7,EHMT2,NSF,FGFBP1,PEX13,KIAA0196,NCOR1,IQSEC2,SMYD3,RTTN,SYT17,BIRC6,PAFAH1B1,HFM1,ACTR3,VTI1A,MYH9,PLEK2,NUP43,CORO6,EEA1,RING1,FLNB,RPGRIP1L,BLOC1S2,TERF2IP,NUBPL,SLX4,ACD,SHC1,KDM2A,FMNL1,WAC,MRPS27,DTNBP1,SSBP1,CEP63,MSH4,KMT2A,RFC4,RFC3,BRD4,KMT2D,PDK1,MTIF2,ASUN,WDPCP,PREX1,ARHGEF10,DLG4,SETD7,DSP,POLG2,TTC28,SNCA,CDC16,SMARCC1,MISP,NSMCE2,ARL13B,IFT140,BRCC3,SETD6,NOLC1,YEATS2,LAMA5,MID1,MAPT,HMGA2,SSH2,C10orf2,TCF3,JMJD6,ATG2B,MON2,CEP126,MLH1,NOL3,OPA1,RPS6KA5,MAD2L2,TADA3,ABL1,GATC,SUV39H2,NEBL,TMSB10,UNC13A,NISCH,ANXA5,HARS2,DYNC2H1,ACTR3B,NUDC,DIS3L2,CEP83,TTLL5,APEX1,MRPS10,CCDC113,PTK2,UBC,MRPL36,ANXA1,RPA1,KLHL22,INF2,NSD1,SRCAP,POLE2,ATM,ANAPC4,KDM4C,CORO2B,KAT6A,CUL7,LETM1,TRIM16,KMT2E,NF1,RARS2,PPARGC1B,FANCD2,BCOR,SIRT2,SEC16A,BIRC2,MRPS30,SMARCB1,DST,ABL2,ANAPC1,KANSL1,CNIH3,ATG3,ANAPC11,XRCC2,ANAPC10,MYH3,RAN,POLE3,CARM1,TRIP13,TIMM50,CDC37,DBN1,FMNL3,BAZ2A,HARS,SIRT6,KATNAL1,TMEM216,COL4A3BP,ATG12,HDAC8,BRCA1,CAV1,KMT2C,PEX1,CXADR,CCDC28B,ARPC3,PAF1,RHOU,TCF7L1,HLCS,CHD3,PER1,E2F4,RAD51B,BBIP1,CHMP4C,USP15,DCTN3,TTN,STX8,SEC24D,TAF1,NKD2,ZIC2,TIMM10,DNAH1,SPIRE1,RNF40,CEP164,CEP290,MBD2,VAPB,CTR9,TIMELESS,ATP6V0D1,KRT20,TRAPPC9,IFT43,USP49,SETD2,HAUS6,ELP3,OBSCN,TRAPPC6B,SYT1,C19orf70,UBE2E1,TCF7L2,ATXN7,BICD1,FSCN1,SNAP23,FAT1,SDCCAG8,HK2,TBPL1,SLC16A1,TBL1X,NAPA,FNBP1L,BRSK2,USP7,CHMP2A,ASH1L,PCNT,CELSR3,ARID2,TNXB,COBLL1,SMARCA4,TNKS1BP1,PIBF1,GBF1,PPP1R9A,KDM1A,MIEF1,DENR,DNAJB6,IKBKB,CCDC40,RNF2,CORO1A,PRMT3,CTC1,KAT8,SEC24A,PHLDB2,EVL,RAB7A,MRRF,VIM,DKC1,RAD54B,ARMC4,IFT81,RBBP8,ATG7,PARD3,TNIK,ESCO1,KIZ,MINK1,ARFIP2,MAP1S,CSNK1A1,GFM2,POGZ,MRPS11,IQGAP2,PEX7,SEC24C,FBL,TTC17,AMOT,MICAL3,KDM6B,PPP1R9B,KDM5B,SMARCAD1,TEX14,TOP3A,HIST1H4J,MEN1,PALLD,RHOT2,CHCHD6,MFN2,TMEM237,GADD45A,WDR35,SET,MSH3,BCAS3,EIF2S1,TAF12 |
| 1.417e-07 | -15.77 | DDX18 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 18) | protein interactions | 8886 | 96 | 34 | 16036 | 2270 |
BCCIP,NIFK,CUL7,FN1,UTP14A,DPF2,SIRT7,NAT10,NOP56,DDX56,MPHOSPH10,SURF2,GLYR1,RNF2,POLR1B,FBL,POLR1E,SNU13,WDR36,DDX24,ABCF2,NOL6,GNL1,DKC1,RBM28,NOP58,PUM3,UBC,PWP1,TSR1,NOL10,HNRNPR,COPS5,POLR1C |
| 1.445e-07 | -15.75 | KARLSSON_TGFB1_TARGETS_UP | MSigDB lists | KARLSSON_TGFB1_TARGETS_UP | 119 | 37 | 17758 | 2279 |
SRM,ARHGAP26,CTU2,HMGA2,WDR75,RWDD1,ACTG1,ACTR3,RSL1D1,BHLHE40,PHGDH,FLNB,C6orf48,EIF2S2,MYC,MMP14,SHMT2,CD44,PPA1,GARS,GNL3,TPM4,USP10,PTK2,KLF6,MAK16,BAZ1A,MYBBP1A,SYNCRIP,PMEPA1,CHD3,SET,EIF2S1,ANXA2,EIF2B3,NOLC1,GCSH |
| 1.448e-07 | -15.75 | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN | 195 | 52 | 17758 | 2279 |
BCCIP,SARS,MCM6,MCM10,MLH1,SMARCB1,DCTPP1,ASNS,SREBF2,COPS3,PAK1IP1,SHMT2,RAN,NDUFA6,ALDH18A1,PRMT3,CDK6,TRIP13,CDC37,MTHFD1,ADARB1,RFC4,EXOSC2,GINS3,CDK4,ABCF2,TPM4,NOL6,VIM,IMPDH2,MCM2,DKC1,MAT2A,STOML2,EXO1,SLC39A14,SLC7A1,POP1,EPRS,BRCA2,SYNCRIP,H2AFX,EIF2S1,SQLE,DPP4,SLC16A1,PRPF4,SENP3,TSEN2,DHCR7,ECHDC1,IPO4 |
| 1.511e-07 | -15.71 | GCM_RAB10 | MSigDB lists | GCM_RAB10 | 164 | 46 | 17758 | 2279 |
FBXO45,ANKRD17,PRKAB2,MON2,IKBKAP,SLC25A44,TTI1,UBR5,EEA1,SPIRE1,NUP133,RASSF3,DCTN4,VPS52,RNF111,TNPO3,RDX,AHCYL1,SRRM2,HSD17B12,SERBP1,VPS13B,FAM98A,HMBOX1,EIF3J,ZFP14,LRRC8A,PITPNB,EVI5,UBE2K,RAB10,FBXL5,ZFAND3,FBXO21,EIF4ENIF1,KIDINS220,KPNA3,GTF2A1,KIAA0355,SOCS4,ZRANB2,MTMR1,TBCK,DMTF1,NMD3,ZNF507 |
| 1.551e-07 | -15.68 | mantle_cell_lymphoma | COSMIC cancer mutations | mantle_cell_lymphoma | 2976 | 469 | 17775 | 2278 |
ARHGAP26,CGN,DCP1B,MKS1,PRKCA,LPAR3,UBR5,GABPB2,RAC3,MGA,PCDH7,PDZD2,MMP7,ZFHX3,NSRP1,ZFYVE28,FAAH2,RABGAP1L,MAD1L1,PDS5B,CHD2,ME1,HRG,CDK6,CNTNAP3B,NRAS,OSBP2,NR6A1,KLHL23,ATG9A,PTPRM,AP4B1,SEMA3F,DDX60,PLCXD2,OSBPL1A,BRCA2,MPV17,VPS13D,SEMA3C,FIS1,RUNX1,NRP1,RFXAP,SPOCK3,SPOCK2,NMD3,HERC2,DROSHA,CELSR1,ANKRD17,ZHX3,TRIO,NHS,DLGAP4,GTF2IRD1,PID1,SLC1A1,ABCA7,SLC39A11,ANXA10,MTUS1,RBM20,PRKCE,NAV1,KIAA1671,USPL1,WDR60,SLC16A9,CCDC88C,CNOT4,FMNL2,GTF2H3,STAG1,PRIM2,KCNQ3,PRDM16,RAPGEF4,TYW1,RYR2,ST6GALNAC3,TPRA1,PLCB1,TRIM37,EVI5,MBNL2,MTR,ATP9B,DAGLA,DYNC1H1,VPS13C,LRP1B,C2orf82,HIF1A,NSF,VCAN,MED15,D2HGDH,RIOK3,DPEP1,KIAA0196,NCOR1,MACROD1,PDLIM5,ARHGAP10,MAP2K4,ZFHX2,COG5,CPT1C,RTTN,TBKBP1,RAB11FIP4,ABCA3,TRPM2,ZNF516,LIN28B,HFM1,KIAA0232,C1QTNF7,VTI1A,CD99L2,MYH9,SPATS2L,NUP43,PTPRG,PABPC1L,UBL5,PDE3A,RPP30,ZNF827,SLX4,ZSWIM7,ACD,ABCA12,TBC1D22A,WAC,NBEA,TTC3,DENND1A,NAA35,LYST,C18orf21,ZCCHC14,KMT2D,GON4L,SFXN4,NPM3,WDPCP,ARHGEF10,SLCO6A1,PREX1,PCNXL2,MARCH6,MEF2D,MEGF11,TTC28,STK10,ERC1,PDE8B,SNCA,DCBLD2,HTR7,ZFAND3,ARHGAP21,IQCH,KDM4B,ASTN2,HIPK2,WDR7,LARGE,MDN1,ANXA2,XRCC4,LAMA5,BAG1,COMMD10,SSH2,BRAF,CA11,C10orf2,SESTD1,TCF3,TRAK1,SF3A3,FARS2,SLC25A12,RCAN1,MLH1,FOXO3,KRI1,NEBL,UNC13A,PMPCA,ANXA5,UPF2,C15orf41,SOX6,NAV3,DDHD1,TMC7,WDFY3,POLK,AGPAT4,ARHGAP39,PACS1,R3HDM2,PPIP5K2,UBE2K,PDE3B,CASC1,CCDC150,MRPL36,TRIB3,RETSAT,PXDN,HERC1,ATM,SLCO5A1,SVIL,MYOM2,SORCS2,ANAPC4,GPATCH4,LRRC41,IMMP2L,CUL7,MVK,ATRX,TRPM6,SLC25A21,PLOD1,SEC16A,PCYOX1L,SMARCB1,RTN1,ZNF804A,ABL2,DST,PHKA1,THADA,JAZF1,ANKRD11,MYH3,ANAPC10,GPATCH1,PCOLCE2,HCFC2,LONP1,CEP128,TMPO,FLNC,METTL1,TNK2,CHD9,GPM6A,SLC3A2,TXLNG,HARS,ZNF680,SKIV2L2,ANK2,CDK4,MED27,GPCPD1,NOL6,KSR2,HDAC8,LAMA2,BRCA1,MTHFD1L,KMT2C,FLVCR1,ST3GAL5,CRYBG3,KIF16B,CCDC3,UBTF,TMEM132B,TCF7L1,MSRA,GATA6,TP53BP1,EEFSEC,E2F4,CSMD3,ABCC3,PRPF4,DLX2,TSEN2,MAGI1,BEND6,RNF214,DCAF5,USP15,CHMP4C,SLC12A7,XYLB,STX8,FN1,RHOBTB1,ITFG1,STXBP6,NKD2,FAN1,MAPK8IP3,ZIC2,EVPL,ARID1B,DNAH1,ETFB,DOPEY1,RNF40,CEP164,KIAA1958,PPIL2,SEMA3D,VAPB,TIMELESS,CTR9,SYNJ2,GMDS,ZCCHC7,NRIP1,SNX29,NT5E,MTHFD1,RANBP6,KRT20,IFT43,ELOVL6,JMJD1C,ZFP14,BCS1L,WDR25,OBSCN,WWC1,SYT1,AGAP1,DNAH14,NR2F1,VAC14,EXOC6,TBC1D2,GRIK4,UBAP2,BICD1,ATAD5,FSCN1,INTS5,FAT1,DNAH17,SDCCAG8,EXOC4,TMEM117,SLC16A1,CDKAL1,DTD1,KIAA1328,ARHGAP12,DDX10,SH3PXD2A,PDSS2,PDE9A,DMXL2,FEZ2,PAPD4,LPCAT2,SMARCA4,RIPK1,ST7L,SSBP2,CSTA,RADIL,PPP1R9A,DDX60L,ZC3H13,BRE,LYPLAL1,SOCS1,NUP133,GRIN2C,ARMC5,SNTG2,CCDC40,MYH15,PRMT3,C6orf89,MAML3,TLCD1,PHLDB2,EVL,COL5A2,TFCP2,THSD4,ANKRD33B,R3HDM1,MRRF,SLC35F2,AKAP13,NUP214,EIF3H,ZNF251,TPK1,BTBD11,SLC30A3,CLEC16A,KLF4,CEBPZ,HEATR1,SMG1,PARD3,ATXN7L2,UNC13D,DYM,PDE4B,CLSTN2,PPHLN1,LETMD1,MED18,SEMA3E,MFHAS1,BMP6,PIP4K2A,MRPS11,IQGAP2,PRKCH,PEX7,NDUFV1,SACS,CWC27,PRICKLE2,DDX31,CD44,TTC17,LDLRAD3,DMRT1,C12orf4,HSD17B12,SLC25A1,SLC6A16,MON1A,SCFD2,TOP3A,DHX34,PEAR1,MARS,YIPF3,PDE2A,ZNF407,NAALADL2,CHCHD6,ARMC3,RERE,MKX,CENPP,CTIF,ZRANB3,CDH24,SRBD1,MPP7,TAF4,CUL2,BCAS3,DNAJC12,PREPL,MMP16,MIPOL1,SLC16A10,ZSWIM6 |
| 1.591e-07 | -15.65 | WELCSH_BRCA1_TARGETS_DN | MSigDB lists | WELCSH_BRCA1_TARGETS_DN | 139 | 41 | 17758 | 2279 |
SRM,MAP2K5,SF3A3,SMARCA4,SLC29A1,SLC6A8,PABPC4,CAD,FARSA,ATIC,MYC,SEC24C,SLC39A7,UBAP2L,PMPCA,SSBP1,KDM5C,FDFT1,RABEPK,MTHFD1,CDC37,SKIV2L,APEX1,NARS,PPAT,CDK4,BMS1,MCL1,MCM2,SOX4,NUP214,SON,MGST1,CHAF1A,RARS,TRAP1,CCDC85B,NOLC1,DDX10,PDCD11,GCSH |
| 1.595e-07 | -15.65 | DNA binding | molecular function | GO:0003677 | 2437 | 401 | 16491 | 2164 |
ZNF292,POLB,HLTF,ZNF44,GABPB2,MGA,ZNF37A,SREBF2,IKZF5,ZFHX3,THAP4,PDS5B,ZNF148,CHD2,KDM5C,MEIS3,ZNF646,DDN,HMBOX1,NR6A1,NFIA,KIF15,TCEB3,CUX1,RFX2,WDHD1,HIST1H2BL,MCM2,DENND4A,SON,DDX60,ZNF197,DOT1L,GZF1,DDX3X,SKIL,ZNF266,BRCA2,RAD18,CCNT1,LSM14A,LUC7L3,ZNF81,HIC2,RUNX1,RFXAP,ZNF532,MEF2C,BANP,EP400,IFT57,EGR1,ZHX3,KHDRBS1,CENPB,GTF2IRD1,PDCD5,CHD5,HR,ZNF586,MCM5,MYC,ZNF326,GTF3C3,PRMT5,ZNF518B,TERF2,MYB,ZNF675,GATAD2B,GTF2H3,PRIM2,RREB1,ZNF587,PRDM16,POLA1,ARID5B,ZNF512B,IMPDH2,ARID1A,ONECUT2,ZNF850,ZNF655,PHF6,ZNF783,ZNF425,GTF2A1,HIF1A,LEMD3,CDK9,SPEN,ZBTB12,ZNF160,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,ZNF516,TRERF1,LIN28B,NPAS2,ZBTB37,FOSL2,SAFB2,ZMAT2,MCM9,PHC2,TERF2IP,CHD7,ZBED2,ZNF827,KDM2A,ACD,ZKSCAN1,GLYR1,SSBP1,MSH4,PEG10,KMT2A,ZC3H3,CASP8AP2,SAP30,PMS1,RFC4,RFC3,KMT2D,BRD4,GON4L,ZNF480,SATB2,MEF2D,PNN,POLG2,SNCA,ZBTB25,VDR,TAF2,ZFAND3,DNTTIP1,MSX2,SMARCC1,ZNF236,H2AFX,HOXA3,CENPBD1,FUS,ZBTB11,XRCC4,HMGA2,SSH2,NOSTRIN,NCOR2,ZNF786,XPC,C10orf2,TCF3,ZNF280C,NFX1,RCAN1,MYNN,MLH1,BHLHE40,ZNF691,FOXO3,ZNF483,ZNF239,ABL1,POLR3D,SUV39H2,YBX3,ZNF710,FBXL19,SOX6,TSHZ1,APEX1,POLK,APTX,ZNF467,OASL,KLF6,FOXC1,POLR2A,ANXA1,RPA1,SRCAP,FBXO21,NSD1,BAZ2B,ZNF155,POLE2,ARID3B,ORC5,ATM,DDIT3,KAT6A,ZNF76,TRIM16,UBN1,ATRX,GPBP1L1,TFIP11,POLR1A,CERS5,ZNF107,BCOR,SNAPC4,SMARCB1,PHF5A,DHX33,XRCC2,HKR1,RELB,ZEB1,POLR3B,ZNF85,POLE3,ZNF3,ETV1,OGG1,LONP1,CARM1,TMPO,ZBTB17,DEAF1,CHD9,ATF4,AEBP2,ZNF124,ZNF195,PPARG,ZNF414,BAZ2A,ZNF680,TSN,BRCA1,SOX4,ZSCAN2,KMT2C,ZNF91,MLLT10,UBTF,TCF7L1,GATA6,TP53BP1,DNAJC1,CC2D1B,CHD3,E2F4,PER1,RAD51B,PQBP1,DLX2,EME1,ZC3H8,ZNF397,DMTF1,MCM6,FOXO1,TAF1,PAX2,DPF2,SMAD7,FAN1,HES6,ZFP36L1,BARX2,ZIC2,RLF,ARID1B,TOX4,RNF141,SUB1,MLX,ZNF358,ZNF354A,MBD2,VPS72,BANF1,NRIP1,POLR1E,ZNF629,ZNF234,PAXBP1,ZBED4,ZFP14,LIG4,PRDM1,TCF7L2,NR2F1,MYBBP1A,PALB2,TBPL1,ZNF430,DTD1,ZFP90,TBL1X,ZBTB24,TCF12,ASH1L,ARID2,SMARCA4,PBX1,ZNF83,ZNF709,SSBP2,TIGD1,ZNF121,KDM1A,ZSCAN5A,RRN3,NRF1,ZBTB21,CAMTA2,DNAJB6,ZNF142,ZFP37,ZNF460,CTC1,AKAP8L,DDX41,TFCP2,PARP2,GRHL3,POU2F1,ATXN1,ZNF251,PUM3,BATF3,RAD54B,EXO1,SMAD3,RBBP8,IKZF4,ADNP,SIX5,ZNF557,KLF4,ZNF333,CEBPZ,ARNTL,ZNF436,ZNF18,NFRKB,ZNF589,ZNF507,DNAJC2,MCM10,SUPT6H,RFX1,AGO2,H2AFJ,MAP1S,FOXP1,POGZ,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,POLR1B,DMRT1,PKNOX1,TOP1,CRAMP1,KDM6B,ARNTL2,TRNP1,MSX1,KDM5B,ZNF821,TEAD1,ZNF654,PSPC1,SMARCAD1,FOXN3,KDM5A,PSMC3IP,TOP3A,SCMH1,ZNF324B,HIST1H4J,MEN1,ZNF407,POLR3A,RERE,ZNF221,MKX,ZNF708,GADD45A,TBX3,SET,TAF4,CSRNP1,MSH3,ZNF32,MYRF,RBPJ,MBD6,TAF12,POLR1C,NR2F2 |
| 1.606e-07 | -15.64 | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 6295 | 917 | 17775 | 2278 |
GNB3,CDCP1,DPH1,ACTG1,DCP1B,AARS2,NAT10,CACNA1H,SBF2,CSPP1,SLC6A8,SYNJ1,LPAR3,CIAPIN1,AMBRA1,NOS1AP,ZNF37A,TOM1L1,PDZD2,MMP7,SREBF2,ZFHX3,THAP4,MAD1L1,PDS5B,KDM5C,AVEN,SRRM2,FTSJ3,PPM1K,NRAS,KLHL23,LIMA1,GNL3,EHMT1,KIF15,C11orf80,WDHD1,AKAP12,PLEKHM3,ABCC2,C10orf76,RBM28,ZNF197,PYCR1,AHNAK,BRCA2,LRRC40,RUNX1,SLC25A26,ZNF532,MEF2C,CARS,HERC2,EP400,CLDN15,FAM189B,KHDRBS1,NHS,RSF1,CLINT1,PARN,PITPNM1,YARS2,ABCA7,RBM20,DDX56,UBE3A,DHX37,INTS7,CACNB2,MED24,WDR60,ANP32B,GEMIN4,MRPL21,PRMT5,COQ3,TOMM34,PABPC1,TIMM8B,COL17A1,ALG6,WDR61,KCNQ3,MYO10,ZNF587,RB1CC1,PRDM16,ARID5B,TYW1,EPS15L1,ZNF512B,RYR2,USP10,MAP7D1,IMPDH2,EVI5,ABCF1,NCDN,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,GTF2A1,NME7,EHMT2,TRAP1,KIAA0196,WDR33,PDLIM5,ARHGAP10,SGSM3,GALE,RAB11FIP4,ABCA3,DNM3,ZNF516,TRERF1,MYH9,FAM122B,LCLAT1,SAFB2,ZMAT2,EEA1,RPGRIP1L,ESAM,ABCA12,ACD,TBC1D22A,SETD5,FMNL1,WAC,CLCN6,MMP14,ATRIP,CEP63,MSH4,MTHFD2L,ZC3H3,LYST,PMS1,KMT2D,KRT7,ARHGEF10,SLCO6A1,ADAM32,PCNXL2,MEF2D,KCNH3,DSP,FKBP3,VPS53,MAT2A,FGFR1,PDE8B,SLC39A14,ZFAND3,PES1,HLA-DMA,ARHGAP21,IQCH,CDC16,ELP2,KDM4B,WDR7,PAM,RPS6KB1,FUS,CENPBD1,ANKS1A,LAMA5,METTL2B,CEP170,YEATS2,MAPT,LRCH1,MORC2,ZNF786,XPC,XRRA1,TRAK1,SF3A3,ATG2B,JMJD6,TGFB2,POM121,KRI1,POLR3D,TAF3,TMSB10,UNC13A,ACOT11,RAPGEFL1,FBXL19,ACTR3B,RPL22L1,SOX6,HNRNPM,SPTAN1,DIS3L2,ULBP1,ERICH1,ARHGAP39,MRPS10,PDE3B,CCDC150,ANXA1,ETFDH,TRIB3,SRCAP,RARS,NSD1,PXDN,ARID3B,HERC1,ACOX1,SLC25A19,PTPN4,AEN,PSAP,BMP4,SORCS2,DOCK6,NUDT22,ANAPC4,KDM4C,CUL7,PPARGC1B,TFIP11,POLR1A,SLC25A21,CSNK2A1,RNF43,TMEM132A,SEC16A,AMPD3,ECM1,DHX33,NCKIPSD,ANKRD11,HKR1,TRIML2,ZNF3,ETV1,SLC25A23,ZMYM2,FAM184A,CDC37,VPS13B,FLNC,DSC3,CHD9,FMNL3,SLC3A2,GCNT2,ATF4,ABCC4,MIOS,BAZ2A,ANK2,NOL6,COL4A3BP,MARCKSL1,LAMA2,BRCA1,KCNH2,ZNF91,CRYBG3,MGST1,PEX1,KIF16B,BSN,GLS,ZNF622,LSS,INSIG1,TP53BP1,CHD3,EEFSEC,TECPR2,TNFRSF1A,SGSM2,C3orf35,PPP3CC,TSEN2,MAGI1,BEND6,RNF214,CTU2,SEPHS2,AOC3,OXNAD1,MCM6,ITFG1,ITPRIP,PRSS3,MAPK8IP3,ZFP36L1,TRIM15,RLF,ARID1B,DNAH1,RNF40,DOPEY1,KIAA1958,MLX,ABCA5,CEP290,VPS72,NDRG4,VAPB,TIMELESS,CTR9,SYNJ2,PNPLA3,ALDH18A1,CWF19L2,SNX29,CAMKK2,LAMC1,USP49,SETD2,HAUS6,WDR25,OBSCN,ZNFX1,TRAPPC6B,SUPT5H,NR2F1,PGD,TBC1D2,PWP1,PRPF40B,ATXN7,FAM135A,SPAG9,PALB2,TTC38,SNAP23,DNAH17,PPP1R12B,SIL1,CASS4,ARHGAP12,PTP4A2,GGT7,DDX10,MPI,SART1,ARID2,RPS29,GPR143,RSL1D1,RIPK1,RNF24,ZNF83,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PAG1,PELP1,DDX60L,PLXNB1,ZNF608,JAG1,UBR1,DNAJB6,FSIP2,C15orf40,ANKRD24,CCDC40,ZFP37,MYH15,AKNAD1,PRMT3,IPO11,CASP10,SKIV2L,SOBP,WDR36,ARHGAP17,AKAP8L,THSD4,MANBAL,AKAP13,CA5B,ENC1,TJAP1,BTBD11,EXO1,IFT81,RANBP2,RBBP8,SIX5,CLEC16A,KLF4,ZNF436,NFASC,PUS1,MED20,MUTYH,PARD3,ATXN7L2,ZNF507,UNC13D,DMGDH,MAP3K13,RFX1,C14orf159,MAP1S,VARS,HIST2H2AB,IQGAP2,TTC1,SACS,ANXA7,TMEM161A,PRICKLE2,DDX31,POLR1B,CPNE7,PCK2,C12orf4,ADAMTSL3,LRRIQ1,SMARCAD1,TEX14,TOP3A,DHX34,PEAR1,FERMT2,PALLD,GPNMB,PIK3CB,TMEM175,ARMC3,NEU1,POLR3G,CENPP,DKK1,CDH24,C20orf196,SRBD1,DSC2,L3MBTL3,TAF4,TBX3,GLG1,MSH3,BCAS3,RBM26,ITGB4,KIF1B,C6orf223,GCSH,ZNF292,MYCBP2,PRDX6,LUZP1,PLRG1,TMEM109,LRP5L,UBR5,AARS,LPIN1,MGA,EXOC1,ZFYVE28,RNF111,PAK1IP1,MEIS3,SEH1L,ZNF646,TBC1D8,DPF3,OSBP2,NR6A1,ATG9A,NOL8,EYA3,CUX1,TCEB3,ZDHHC14,DENND4A,SON,DDX60,MAK16,DOT1L,OSBPL1A,TRRAP,LSM14A,SH3RF1,LUC7L3,VPS13D,XPNPEP1,DNAH2,NRP1,TXN2,FAM118A,BMI1,ZNF598,SYNPO,PTPN14,WDR75,IFT57,CELSR1,ANKRD17,PRPF31,DLGAP4,NDUFS7,MTUS1,IGF2BP3,ANXA10,FAM192A,PRKCE,SLC7A11,USPL1,MYC,PIGG,SLC16A9,IGF2BP1,RTFDC1,TERF2,FDFT1,USE1,SIK3,DDX28,RREB1,SYNGAP1,AOC2,RAPGEF4,RAP1GAP2,KIAA0586,TTYH2,ARID1A,MTR,SLC26A11,ANGPTL4,ARIH2,ATP9B,CAT,EPRS,ASCC3,KIDINS220,PMEPA1,UBAP1,HIF1A,SRRD,VCAN,SPEN,ZZEF1,D2HGDH,ZCCHC6,DPEP1,PEX13,NCOR1,HS2ST1,CPT1C,RTTN,TRPM2,CCDC58,BIRC6,URB2,C1QTNF7,KLHL18,TMEM104,PLEK2,PTPRG,IGSF1,BLOC1S2,PHC2,CHD7,NUBPL,FLAD1,TERF2IP,ZNF827,DECR1,SHC1,KDM2A,ARMC6,VGF,LPIN2,SOCS6,TTC3,SERPINH1,KMT2A,PLEKHA4,ZCCHC14,RFC4,GON4L,PREX1,LRRC8A,DLG4,GNL1,SATB2,MARCH6,MEGF11,MED16,GALK2,SETD7,STK10,ERC1,DHX57,DCBLD2,ZBTB25,MSX2,WDR5B,SMARCC1,MBTD1,ZNF236,LARGE,IFT140,TRMT2A,CBWD1,TRAF3,MDN1,KLHDC4,ANXA2,NOLC1,MID1,TROVE2,NCOR2,SSH2,BRAF,C10orf2,TCF3,SLC25A12,RTN4,MLH1,LIAS,MON2,GIGYF2,FOXO3,FAM8A1,NEDD4,ABL1,ZNF483,PTRF,NEBL,NISCH,PMPCA,UPF2,RDX,DYNC2H1,PLEKHG4,NAV3,CLK2,FAM120B,TMC7,TSHZ1,TTLL5,PXN,APEX1,ZFYVE1,WDFY3,FZD3,BMS1,C9orf153,SLC23A2,YIF1A,KLHL22,RETSAT,ZDHHC11,DDX50,HNRNPH3,COQ9,ATM,SVIL,MYOM2,APAF1,IPO4,SLC43A1,ZNF76,LETM1,PHF3,NF1,ATRX,RARS2,KIF5A,TRPM6,ZNF107,PLOD1,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,EDC3,SMARCB1,RTN1,ZNF804A,DST,ANAPC1,YLPM1,THADA,LONRF2,MYH3,RELB,IPP,PCOLCE2,KIAA0922,NDUFA6,HCFC2,YARS,CCDC121,LONP1,TIMM50,LAMA4,ZBTB17,DTNB,DEAF1,SESN2,ZNF195,ZNF680,ARRDC3,VWCE,TFPI,MTHFD1L,TCTN1,ST3GAL5,SERGEF,CDHR3,CHAF1A,CCDC3,TMEM132B,RHOU,PAF1,EPN2,SUFU,TRMT5,DNAJC1,CC2D1B,MKL2,CSMD3,ABCC3,GALNT10,EME1,DCAF5,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,FN1,RHOBTB1,TAF1,ALG8,PCSK7,MED13L,EVPL,QSER1,XPO7,CMTM3,CEP164,RNF141,ELL,SIPA1L3,ATXN2,SEMA3D,PRF1,AKAP11,N4BP2,HSD17B14,ZNF234,KRT20,PDE4A,TSTA3,PPAT,ELP3,JMJD1C,TBXAS1,ZFP14,WWC1,PRDM1,CORIN,AGAP1,EXOC6,MGAT2,APBB3,SYCP2L,UBAP2,BICD1,ATAD5,MYBBP1A,KIAA0355,INTS5,FAT1,SDCCAG8,EXOC4,TMEM117,CDKAL1,KIAA1328,ZFP90,TBL1X,FNBP1L,PDSS2,C7orf26,DMXL2,TCF12,ASH1L,PCNT,CELSR3,PSTPIP2,TMEM183A,MYO7A,SMARCA4,TBCCD1,COBLL1,SPATS2,ST7L,GBF1,DHX35,SLC39A1,RIOK2,ZC3H13,RAET1E,VPS18,CAMTA2,PPFIBP1,SNTG2,ZNF142,MET,ITGAX,ZNF460,C6orf89,HTRA2,MAML3,MCEE,RTN4RL2,COL5A2,PTBP2,PARP2,METTL2A,GRHL3,ATXN1,POU2F1,R3HDM1,MRRF,ATP8B2,UBR4,PUSL1,S100A16,TPK1,RAD54B,PLIN2,ZC3H12A,ARMC4,ALAD,IKZF4,HYAL3,KPNA3,ADNP,COPS5,CEBPZ,SCARB1,TMEM101,NFRKB,HEATR1,USP11,ECHDC1,SMG1,TMEM33,TMCC1,YDJC,BCKDK,SH2D3A,SUPT6H,CAMK1,DYM,CLSTN2,PPHLN1,LETMD1,WDR26,ATF7IP,CCDC7,FAM49A,BMP6,MFSD10,SFI1,PRKCH,GART,HAS3,SEC24C,DSG2,TANK,KDELC1,LDLRAD3,FBL,UTS2,MICAL3,PKNOX1,SLC25A1,TOP1,KDM6B,SLC6A16,MSX1,ZNF821,SCMH1,ARHGAP32,MEN1,LENG8,ZNF407,NAALADL2,NAPEPLD,SYMPK,TARS,RERE,WDR35,AGTPBP1,ARHGAP27,HRH1 |
| 1.698e-07 | -15.59 | covalent chromatin modification | biological process | GO:0016569 | 342 | 79 | 16441 | 2138 |
USP7,ASH1L,TRIM16,KMT2E,BCOR,SIRT2,PRKCA,RING1,KDM1A,KDM2A,KANSL1,WAC,RNF2,KDM5C,POLE3,KMT2A,PRMT3,CARM1,KAT8,KMT2D,BRD4,SETD1B,SIRT6,BAZ2A,EHMT1,EYA3,HDAC8,SETD7,KMT2C,DOT1L,PAF1,BRCA2,TRRAP,HLCS,PER1,BRCC3,SETD6,YEATS2,USP15,HMGA2,WDR75,EP400,TAF1,TCF3,SIRT7,JMJD6,RPS6KA5,CDC73,CHD5,TADA3,RNF40,SUV39H2,MBD2,MED24,CTR9,PRMT5,FBL,MAP3K12,KDM6B,WDR61,KDM5B,USP49,SMARCAD1,ELP3,SETD2,HIST1H4J,MEN1,TRIM37,UBE2E1,NSD1,SRCAP,ATXN7,EHMT2,ATM,TBL1X,TAF12,SMYD3,KDM4C,KAT6A |
| 1.751e-07 | -15.56 | DEXDc | smart domains | SM00487 | 109 | 36 | 9131 | 1249 |
EP400,ATRX,DDX18,HFM1,DDX19A,SMARCA4,HLTF,DHX35,CHD5,DDX60L,CHD7,DDX56,DHX37,DHX33,CHD2,DDX31,SKIV2L,CHD9,DDX28,DDX24,DDX41,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,RAD54B,ZRANB3,DDX3X,SRCAP,ASCC3,DDX50,CHD3,DDX10 |
| 1.768e-07 | -15.55 | mouth | COSMIC cancer mutations | mouth | 9422 | 1321 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,DPH1,ACTG1,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,HMOX2,SLC6A8,LPAR3,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,NRAS,UPP1,EHMT1,KIF15,WDHD1,ABCC2,SLC7A1,AHNAK,LRRC40,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,ZNF532,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,DHX37,APLF,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,NOM1,RABEPK,ZNF675,IFRD1,STAG1,ALG6,KCNQ3,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,SNAP25,ARRDC4,TRIM37,SRA1,IRS1,DYNC1H1,KPNA1,GSTO2,PDLIM1,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,ARHGAP10,RAB11FIP4,MAB21L3,NUP43,MCM9,RPGRIP1L,CD96,ESAM,ACD,SETD5,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,ZC3H3,KIAA1549,LYST,KMT2D,ZNF480,SLCO6A1,PCNXL2,MEF2D,KCNH3,NUDT15,DSP,VPS53,KDM4B,ASTN2,ARL13B,POLR3E,RPS6KB1,CENPBD1,CEP170,CATSPERG,BAG1,MAPT,RAB30,MORC2,HMGA2,ATG2B,IP6K2,TRIM22,SNW1,CFDP1,UNC13A,ACOT11,LTN1,RAPGEFL1,ZNF710,FBXL19,C15orf41,SAMD4A,RPL22L1,SPTAN1,VPS37A,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,PPIP5K2,UBC,CCDC150,NSD1,SRCAP,HERC1,ACOX1,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,MAP2K3,AMPD3,ECM1,ANKRD11,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,FMNL3,RBCK1,MIOS,CDK4,ANK2,MARCKSL1,LAMA2,KCNH2,KRTCAP2,DLST,BSN,DYRK1B,TCF7L1,LSS,INSIG1,CHD3,E2F4,DPP4,ADAM9,PPP3CC,MAGI1,CTU2,FOXO1,CLK1,NKD2,MAPK8IP3,ARID1B,SPIRE1,ZNF358,CEP290,VPS72,VAPB,CTR9,LRSAM1,SNX29,IFT43,SETD2,HAUS6,OBSCN,TCF7L2,TBC1D2,GRIK4,TTC38,CASS4,GGT7,USP7,MPI,SART1,OLFM2,PAPD4,UPK3B,ARID2,OSBPL9,NTSR1,LAGE3,RIPK1,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,ZNF121,URB1,PLXNB1,ZNF608,IDI1,JAG1,GRIN2C,FGGY,CCDC40,MYH15,IPO11,PRPF19,KDM3B,SSFA2,TEX19,KIRREL2,VIM,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,LMBR1L,EIF2B3,PARD3,DMGDH,ESCO1,RFX1,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,TMEM161A,POLR1B,CPNE7,LRRIQ1,MON1A,SMARCAD1,ABCF2,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,SMPDL3B,POLR3A,CDH24,CACNB1,NOL10,TAF4,TBX3,BCAS3,USP20,RBM26,RBPJ,NR2F2,XPO6,KIF1B,ZNF292,LUZP1,PRKCSH,PRKCA,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,CSGALNACT2,ZNF646,ACADS,OSBP2,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,DDAH2,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,CFD,HIC2,NRP1,WDR66,RFXAP,SPOCK3,SPOCK2,ZMAT3,CADM4,PRPF38B,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,MTUS1,TECTA,HR,NOVA2,USPL1,SCAF1,PIGG,CNOT4,FDFT1,EXOSC2,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1B,ARID1A,TPRA1,SLC26A11,MTR,PHF6,ATP9B,ASCC3,MTHFD2,VCAN,SPEN,MED15,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,UROD,TMEM104,PLEK2,PTPRG,PABPC1L,FLNB,IGSF1,DECR1,SLX4,ASNS,ARMC6,PPID,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MEGF11,SETD7,ERC1,HSD3B7,ZBTB25,BAZ1A,DNTTIP1,SMARCC1,WDR5B,G6PD,FTSJ1,LARGE,IFT140,SLC4A7,TBXA2R,SETD6,MID1,SSH2,BRAF,B4GALT5,FARS2,KIF5C,OPA1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,FER1L5,SLC40A1,PXN,TTLL5,ZFYVE1,PACS1,BMS1,KLF6,GUF1,SLC23A2,DDX50,ATM,SVIL,NDUFS5,IPO4,DDIT3,ZNF76,ATRX,PCYOX1L,DST,ANAPC11,SLC39A7,MYH3,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,TNK2,DEAF1,FBXW4,SESN2,ARRDC3,VWCE,TMEM216,KSR2,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,TIMM44,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,EME1,CLU,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,SMG7,EVPL,ELL,CCDC124,PRF1,HSD17B14,ZNF629,PPAT,ELOVL6,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,MGAT2,POP1,APBB3,BICD1,KIAA0355,FSCN1,FAT1,KIAA0754,TMEM117,CDKAL1,TBL1X,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,DMXL2,FEZ2,SMARCA4,TBCCD1,ARSJ,PIBF1,SBDS,ZC3H13,SOCS1,PPFIBP1,SNTG2,ITGAX,TMEM120B,C6orf89,AUP1,MAML3,PRAME,METTL2A,GRHL3,ATXN1,EDEM2,UBR4,ARMC4,ALAD,IKZF4,DUS3L,HNRNPR,ZNF557,CEBPZ,WDR73,ARNTL,TMEM101,ARC,RNF130,NFRKB,SMG1,DNAJC2,BCKDK,SUPT6H,ARL15,DYM,PDE4B,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,FAM49A,MFHAS1,GFM2,BMP6,SCN1B,SEC24C,STC2,DCTN4,LDLRAD3,ERI3,MICAL3,RPS6KB2,TOP1,MARCH9,KDM6B,SLC6A16,DNMBP,FGF2,CRIM1,PSPC1,KDM5A,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,CTIF,ZNF221,DAGLB,WDR35,AGTPBP1,VPS37B,NFKBIB,ZSWIM6,GNB3,CACNA1H,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,NEK6,SREBF2,RABGAP1L,RASSF3,FAAH2,PDS5B,WIZ,HRG,FXN,CDK6,PTPRM,GNL3,RFX2,AKAP12,MSRB3,C10orf76,TMSB4X,STOML2,DDX3X,BRCA2,TMEM139,MEF2C,HERC2,CARS,KHDRBS1,NHS,RSF1,KCNJ14,SLC1A1,ABCA7,SLC39A11,DDX56,EIF2S2,INTS7,MCM5,NOC3L,PRMT5,MAP3K12,ZNF518B,COQ3,FMNL2,SERBP1,HMGCR,FADS1,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,CPT1A,ONECUT2,EVI5,ABCF1,NCDN,ZNF655,VPS13C,LRP1B,GTF2A1,LEMD3,SURF1,ZNF160,WDR33,MB21D2,SPRED2,ABCA3,ZNF516,DNM3,NPAS2,ATP6V1A,BTBD2,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,LSM10,GARS,KRT7,FAM111B,ARHGEF10,ADAM32,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,TAF2,GNG2,PES1,CDC16,IQCH,HIPK2,WDR7,PAM,FUS,ZBTB11,ANKS1A,LAMA5,YEATS2,LRCH1,SERINC5,ZNF786,XPC,SESTD1,TRAK1,WDR37,AKT1S1,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,GATC,SUV39H2,PVRL3,ACAP3,ARHGAP1,HNRNPM,SOX6,DIS3L2,DDHD1,C21orf58,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,FAM126B,PDE3B,CASC1,RPA1,KISS1R,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,ARID3B,PLPPR2,PTPN4,SLC25A19,SLCO5A1,PSAP,GPAM,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,POLR1A,TFIP11,PPARGC1B,MFGE8,CSNK2A1,SEC16A,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,UBAP2L,ZNF85,RAN,ETV1,CDC37,SF3A1,PTPRK,TMPO,FLNC,METTL1,CHD9,SLC3A2,ZNF124,HARS,SKIV2L2,ZNF414,BAZ2A,GDPD1,MED27,BRCA1,ZNF91,CCDC28B,PEX1,KIF16B,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,RAD51B,SGSM2,SEPHS2,AOC3,ITPRIP,HSD17B10,MEX3A,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,ABCA5,PDE10A,SAMD11,GTF2H1,SYNJ2,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,TLE3,BCS1L,RNH1,MEX3B,SUPT5H,TRAPPC6B,VAC14,NR2F1,PGD,NAP1L5,ATXN7,FAM135A,ITPRIPL1,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,ZNF430,PPP1R12B,HMBS,PRKAR2A,KCTD7,CYLD,GPR143,ZNF709,PELP1,KDM1A,CAD,UBR1,DNAJB6,ARMC5,C15orf40,ZDHHC6,HIBCH,ETF1,ANO8,ZFP37,CORO1A,AKNAD1,CTC1,CASP10,TMEM200A,SEC24A,WDR36,PCGF3,NARS,GLTSCR2,THSD4,MANBAL,AKAP13,ENC1,NUP214,TMEM186,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,ZNF333,ITGA2,ZNF436,TSSC1,PRRT3,PUS1,NFASC,ZNF18,SEPT5,UNC13D,MAP3K13,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,FAM50A,SACS,ANXA7,PRICKLE2,DDX31,PCK2,FAM71E1,ADAMTSL3,ZMYM5,DHX34,TEX14,PEAR1,C11orf49,RHOT2,TMEM175,PIK3CB,ARMC3,CENPP,POLR3G,TPD52L2,MSH3,GLG1,EIF2S1,ITGB4,RPS6KC1,MIPOL1,MYCBP2,CGN,PRKAB2,TNFRSF21,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,GIPR,VPS52,PAK1IP1,RNF111,ME1,CEP135,MEIS3,FUT11,TBC1D8,DDN,DPF3,SETD1B,CUX1,SKIL,HSDL2,ZNF81,VPS13D,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,TGFBR2,CHD5,IGF2BP3,PRKCE,NAV1,PI4KB,ASAP1,COPS3,VWDE,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,POLA1,AOC2,KIAA0586,TTYH2,PTPN12,PLCB1,LYRM7,ZNF425,DAGLA,EPRS,KIDINS220,NSF,UBAP1,PMEPA1,ZZEF1,ZBTB12,PURB,PEX13,UMPS,IQSEC2,MAP2K4,RTTN,PTCD2,TBKBP1,AMOTL1,TRPM2,RWDD1,URB2,HFM1,OLA1,KLHL18,SLC25A44,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,TMEM184A,SHC1,KDM2A,VGF,NBEA,SSBP1,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,RFC4,ZCCHC14,PDK1,MTIF2,WDPCP,DLG4,GALK2,MED16,TBC1D16,STK10,CPED1,VDR,HTR7,DNAJA3,ZNF236,ALKBH1,TRMT2A,ANXA2,MDN1,PDCD11,TROVE2,NCOR2,C10orf2,TCF3,ZNF280C,SLC25A12,MYNN,RTN4,MON2,MLH1,IKBKAP,GDPD5,FOXO3,TMCO6,NEDD4,DCTPP1,ZNF239,RGS17,PTRF,NISCH,UPF2,COPS7B,NLGN3,EXOSC4,PLEKHG4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,OASL,ECH1,FBXO21,KLHL22,ZDHHC11,HELZ,MYOM2,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,MVK,PHF3,FEM1C,UBN1,NF1,PTPRA,FANCD2,TRPM6,PLOD1,RCHY1,ZNF107,BCOR,SNAPC4,CUTC,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ZNF804A,LONRF2,THADA,YLPM1,RELB,JOSD1,POLR3B,PCOLCE2,SLC27A5,NDUFA6,TRIM14,PRKACB,LONP1,TIMM50,ZBTB17,LAMA4,GPM6A,TRIM13,TXLNG,CMIP,SOX4,TCTN1,CDHR3,CHAF1A,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,SUFU,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,ZNF397,DMTF1,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,PAX2,MED13L,XPO7,PHGDH,RHBDD1,ETFB,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,CCDC112,GLTP,N4BP2,CPSF3L,KRT20,RANBP6,PDE4A,TBXAS1,WWC1,PSMA1,PRDM1,ANKRD20A4,DNAH14,ISG15,ATAD5,MYBBP1A,INTS5,SDCCAG8,HK2,EXOC4,KIAA1328,ZFP90,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,GBF1,VPS18,FARSA,CAMTA2,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,MCEE,PHLDB2,FAM172A,SFSWAP,NLN,R3HDM1,ATP8B2,RAB10,PUSL1,RAD54B,WARS,TPK1,ZC3H12A,PLIN2,HYAL3,ADNP,SRFBP1,SCARB1,HEATR1,USP11,ECHDC1,TSPAN5,KLHL24,YDJC,TNIK,SH2D3A,SULT1C2,DBF4,NSUN6,CLSTN2,PPHLN1,MFSD10,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,DSG2,SHMT2,CLDND1,DMRT1,PSMC3IP,ANKMY2,MARS,PHACTR2,ARHGAP32,LENG8,MEN1,ZNF407,TARS,RERE,ZNF708,ALG5,MPP7,MBD6,TATDN1,ZAK,MMP16,CTXN1,HRH1 |
| 1.799e-07 | -15.53 | follicular_lymphoma | COSMIC cancer mutations | follicular_lymphoma | 1269 | 224 | 17775 | 2278 |
IMMP2L,ATRX,FANCD2,SLC25A21,CACNA1H,RNF43,PRKCA,NUP160,NOS1AP,TOM1L1,PCDH7,EXOC1,ECM1,YLPM1,TRIML2,GPATCH1,ME1,POLR3B,ETV1,SPAG6,CARM1,ZNF646,TBC1D8,DSC3,CCDC57,NRAS,SETD1B,PTPRM,KATNAL1,GPCPD1,KIF15,ATG12,LAMA2,KMT2C,SON,TMEM132B,MSRA,BRCA2,CCNT1,MPV17,CSMD3,DPP4,DNAH2,RIOK1,GREB1L,TPM1,USP15,VIPR1,FOXO1,SEC24D,ANKRD17,TAF1,ITFG1,TRIO,NHS,OPHN1,CENPB,ZFP36L1,ARID1B,SLC1A1,IGF2BP3,MTUS1,TECTA,DOPEY1,UBE3A,MCAM,ENTPD5,SLC38A5,CEP290,USPL1,SCAF1,PDE10A,CCDC112,AGL,ZCCHC7,FADS1,SIK3,IFRD1,SYNGAP1,PRDM16,PCCA,EPS15L1,JMJD1C,RAP1GAP2,KIAA0586,RYR2,ST6GALNAC3,ARID1A,SYT1,AGAP1,ZNF655,VAC14,TBC1D2,DYNC1H1,PRPF40B,GRIK4,LRP1B,UBAP2,TASP1,BICD1,CCDC85B,ZCCHC6,SNX24,TMEM117,CDKAL1,DTD1,CNOT6,ARHGAP12,ZFP90,HMBS,PDLIM5,NAPA,PDE9A,COG5,VMA21,RTTN,SYT17,TRPM2,DNM3,BIRC6,PAPD4,ARID2,NPAS2,URB2,ACTR3,GPR143,LPCAT3,PTPRG,TIGD1,RADIL,PIBF1,EEA1,STAM,PLXNB1,PDE3A,KDM1A,ZNF827,BRE,SOCS1,ERI1,NUP133,SNTG2,AKNAD1,AHCYL1,ITGAX,PLEKHA4,CDK12,IPO11,LYST,CTC1,SKIV2L,KMT2D,FAM172A,SSFA2,ZNF480,SLCO6A1,SATB2,MARCH6,TTC28,ERC1,SMAD3,ARHGAP21,RANBP2,ASTN2,PEMT,CAMKMT,TSSC1,SLC4A7,RNF130,TSPAN5,MID1,METTL2B,SMG1,PARD3,LRCH1,COMMD10,TNIK,BRAF,AUH,DYM,DBF4,C1orf226,ZNF280C,VARS,SEMA3E,MON2,RBM19,IKBKAP,RSRC1,MBNL1,MFHAS1,NEDD4,KRI1,PTPN2,COMMD9,PVRL3,DSG2,CD44,LDLRAD3,SOX6,KDM6B,TSHZ1,AGPAT4,WDR18,PPP1R21,ARHGAP39,ARHGEF12,NAALADL2,CHCHD6,ARMC3,SMPDL3B,CCDC150,OXSR1,BAZ2B,IREB2,MPP7,BCAS3,ATM,SORCS2,ITGB4,BRWD3,RPS6KC1,ADK,MMP16 |
| 1.818e-07 | -15.52 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP | 191 | 51 | 17758 | 2279 |
THOC5,URB2,ST6GAL1,MRI1,UROD,KIAA0232,HSD17B10,SLC25A12,POP5,IKBKAP,GIT2,SPIRE1,CIAPIN1,PCYOX1L,CEP164,SUV39H2,ZNHIT6,CTR9,POLR3B,CORO1A,HCFC2,TRMT12,POLR1E,IPO11,DDX28,ZNF234,FAM172A,ALG6,MIOS,IFNGR2,CDK4,ANKMY2,SCFD2,BCS1L,PTK2,ARID1A,DKC1,FOXRED1,TRIM37,NAPEPLD,USP46,PEX1,POP1,FBXO21,TASP1,ALAD,COQ9,HEATR1,HMBS,PRKAR2A,MTCH1 |
| 1.839e-07 | -15.51 | small molecule binding | molecular function | GO:0036094 | 2600 | 424 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,NT5C3A,PRKCA,SYNJ1,RAC3,AARS,PABPC4,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,ACADS,NRAS,SETD1B,OSBP2,GNL3,NOL8,KIF15,ABCC2,MCM2,DDX60,RBM28,OSBPL1A,GNAI1,DDX3X,DDAH2,BDH2,DNAH2,RIOK1,DIRAS1,RUNX1,RBP1,CARS,EP400,LARS2,SLK,TRIO,SIRT7,AK6,PIK3R4,TGFBR2,PARN,CHD5,SLC1A1,YARS2,ABCA7,IGF2BP3,RBM20,PRKCE,DDX56,PI4KB,DHX37,APLF,MCM5,IGF2BP1,CNOT4,MAP3K12,PRPS1,PABPC1,HMGCR,SIK3,DDX28,MYO10,POLA1,PCCA,EIF4A2,RAPGEF4,IDH3G,TYW1,RAP1B,IMPDH2,MTR,ABCF1,ATP9B,CAT,DYNC1H1,ASCC3,EPRS,NME7,ALKBH3,NSF,TRAP1,LEMD3,CDK9,SPEN,D2HGDH,RIOK3,GPN1,SQLE,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,PABPC1L,SAFB2,LTB4R,CBWD5,HNRNPA3,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,DECR1,PRKD3,ASNS,ABCA12,GLYR1,CLCN6,NT5C,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,FGFR1,DHX57,SNCA,VDR,CAMK2D,HIPK2,G6PD,DNAJA3,ARL13B,PAM,CBWD1,TRMT2A,RPS6KB1,FUS,MDN1,NOLC1,RAB30,VWA8,BRAF,SESTD1,C10orf2,FARS2,KIF5C,GAS6,IP6K2,MLH1,OPA1,RPS6KA5,NEDD4,DCTPP1,TTLL11,ABL1,FTCDNL1,CBWD6,GATC,HARS2,CELF1,DYNC2H1,MAP3K14,NT5M,ACTR3B,HNRNPM,CLK2,NAV3,PFKFB4,TTLL5,DDX24,LDHA,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,ETFDH,SRCAP,RARS,DDX50,HELZ,ACOX1,HNRNPH3,ORC5,ATM,APAF1,ADK,STK4,MVK,RBM33,ATRX,NF1,RARS2,PPARGC1B,KIF5A,MFGE8,TRPM6,CSNK2A1,PLOD1,SIRT2,STK33,HNRNPLL,SCAF8,MAP2K3,SRPRB,ABL2,RAP1A,SRSF2,DHX33,TRMU,XRCC2,MYH3,POLR3B,RAN,SLC27A5,YARS,LONP1,TRIP13,PRKACB,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,SIRT6,PPARG,ITPA,HARS,KATNAL1,CDK4,HSPA5,KSR2,CAV1,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HPRT1,HLCS,CHD3,FAM114A2,ARL4A,EEFSEC,RAD51B,CRCP,ABCC3,MAGI1,TNRC6A,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,RHOBTB1,TAF1,HSD17B10,PHGDH,DNAH1,P3H1,ABCA5,MBD2,PDE10A,SYNJ2,ALDH18A1,GMDS,N4BP2,NT5E,MTHFD1,MSI2,WARS2,CAMKK2,PDE4A,TRA2A,BCS1L,LIG4,OBSCN,AGAP1,ACOXL,DNAH14,UBE2E1,PGD,ATAD5,SYNCRIP,DNAH17,IRAK2,RRAGA,HK2,SIL1,HMBS,DDX10,TBCK,BRSK2,PRKAR2A,CHMP2A,SUCLG1,PAPD4,RBFOX2,MYO7A,GPR143,SMARCA4,RIPK1,DHX35,DDX60L,KDM1A,MIEF1,RIOK2,CAD,FARSA,ZBTB21,DUS4L,UBR1,NVL,CBR4,RPS6KL1,IKBKB,MYH15,FHIT,MET,TMLHE,SKIV2L,NARS2,ACSL5,TUBA1A,PTBP2,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,ATP5D,WARS,TPK1,RAD54B,DUS3L,HNRNPR,SCARB1,SEPT5,SMG1,BCKDK,TNIK,NIFK,MINK1,DNAJA4,MAP3K13,ARL15,CAMK1,PDE4B,TKFC,ARFIP2,APRT,IGF2BP2,VARS,RBM19,CSNK1A1,ENOX1,RMI1,PIP4K2A,MFHAS1,GFM2,PRKCH,ADH5,NDUFV1,GART,SHMT2,DDX31,POLR1B,PCK2,MICAL3,RPS6KB2,GPHN,PSPC1,SMARCAD1,ABCF2,DHX34,TEX14,MARS,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,MFN2,HSPA1B,MSH3,NCBP2,RBM26,NR2F2,RPS6KC1,KIF1B,ZAK |
| 1.897e-07 | -15.48 | cellular component biogenesis | biological process | GO:0044085 | 2108 | 350 | 16441 | 2138 |
CGN,ACTG1,AARS2,MRPL10,MKS1,SBF2,PRKCA,COA1,SYNJ1,RAC3,LPAR3,CIAPIN1,SKI,RPS16,NEK6,S100A10,WIZ,ME1,CEP135,FXN,FTSJ3,ACADS,SNU13,ATG9A,LIMA1,GNL3,NOL8,HIST1H2BL,MCM2,FOXRED1,CLNS1A,STOML2,DDX3X,SKIL,AHNAK,LSM14A,LUC7L3,FIS1,TPM1,CCNB1IP1,SPOCK2,NMD3,CLDN15,IFT57,DROSHA,TRIP6,JUP,PRPF31,OPHN1,RSF1,PRPF39,SLC1A1,NDUFS7,ABCA7,FKBP1A,DDX56,HR,MED24,ANP32B,GEMIN4,CCDC88C,PRMT5,CAV2,NOM1,HMGCR,SCAF11,DDX28,BDNF,EXOSC2,COL17A1,TSPYL4,RB1CC1,KIAA0586,RAP1B,SNAP25,IMPDH2,CPT1A,TRIM37,ONECUT2,ABCF1,ANGPTL4,SEC31A,CAT,DYNC1H1,EPRS,TSR1,NSF,SURF1,KIAA0196,NCOR1,SMYD3,VMA21,DNM3,PAFAH1B1,C1QTNF7,ISG20L2,RPGRIP1L,NOP56,BLOC1S2,CHD7,NUBPL,DECR1,ACD,ERI1,PPID,MSH4,CEP63,KMT2A,MPP6,EIF3J,NPM3,WDPCP,ARHGEF10,PREX1,DLG4,ATP6V0A1,GNL1,PES1,TAF2,HLA-DMA,CAMK2D,DCXR,ARL13B,H2AFX,IFT140,MDN1,ANXA2,PDCD11,NOLC1,LAMA5,HMGA2,SHQ1,BRAF,UTP14A,C10orf2,SF3A3,ATG2B,GAS6,TRIM22,CEP126,MLH1,IKBKAP,NOL3,MBNL1,DCTPP1,PSMG4,NEBL,NOP16,PVRL3,ANXA5,RDX,NLGN3,CELF1,DYNC2H1,EXOSC4,DIS3L2,PXN,CEP83,VPS37A,TTLL5,KCNMA1,ADSL,BMS1,CCDC113,PTK2,UBE2K,NOP58,UBC,MRPL36,NDUFS5,APAF1,UQCC1,IPO4,KAT6A,IMMP2L,EIF3C,UBN1,ATRX,TRPM6,SIRT2,NLE1,COX10,SEC16A,CUTC,BIRC2,EDC3,DST,ABL2,RAP1A,CNIH3,ZNHIT6,ATG3,MARVELD2,XRCC2,MYH3,RAN,LONP1,TRIP13,SF3A1,PTPRK,SRPK2,FLNC,GPM6A,SKAP2,SKIV2L2,BAZ2A,MINA,NOL6,TMEM216,PSMG1,ATG12,CAV1,LSG1,MGST1,BSN,CCDC28B,CHAF1A,GLS,GEMIN5,PAF1,HPRT1,ZNF622,E2F4,RAD51B,TNFRSF1A,BBIP1,CLU,MAGI1,UQCC2,NOCT,FBXO45,TTN,FN1,TAF1,SEC24D,VTA1,SMAD7,HSD17B10,DNAH1,SPIRE1,CEP164,CEP290,MBD2,ATXN2,LRSAM1,PRF1,POLR1E,ATP6V0D1,RANBP6,TRAPPC9,LAMC1,PPAT,HAUS6,WBSCR22,UTP15,BCS1L,OBSCN,EIF2A,TRAPPC6B,SYT1,NAP1L5,SPAG9,BICD1,FSCN1,SNAP23,TBPL1,NAPA,FNBP1L,PDSS2,AGO3,KCTD7,CHMP2A,SART1,CYLD,PCNT,CELSR3,SLC2A1,MYO7A,TNXB,COBLL1,RIPK1,PIBF1,SBDS,DENR,METTL16,RRN3,KCTD11,MPHOSPH10,NVL,CBR4,CCDC40,CORO1A,VCL,TMEM120B,UTP4,PRPF19,SEC24A,WDR36,EVL,PTBP2,RAB7A,THSD4,C1QTNF1,METTL15,DKC1,EIF3H,SMAD3,ARMC4,IFT81,ALAD,KPNA3,SRFBP1,HEATR1,NFASC,AP2S1,PARD3,TMEM33,TNIK,NIFK,MINK1,HM13,AGO2,ARFIP2,POGZ,MRPS11,HAS3,SEC24C,HIST2H3D,SHMT2,DDX31,POLR1B,TTC17,ERI3,FBL,AMOT,PPP1R9B,GPHN,SMARCAD1,FERMT2,HIST1H4J,CENPP,CDH24,TMEM237,WDR35,MPP7,SET,VPS37B,NCBP2,NDUFAF5,ITGB4 |
| 1.949e-07 | -15.45 | DHX37 (DEAH (Asp-Glu-Ala-His) box polypeptide 37) | protein interactions | 57647 | 17 | 12 | 16036 | 2270 |
RGS17,DDX56,NIFK,TRIP6,WDR74,SIRT7,NAT10,ATXN1,PRPF4,RBM19,POLR1C,TERF2 |
| 2.046e-07 | -15.40 | NOP58 (NOP58 ribonucleoprotein) | protein interactions | 51602 | 93 | 33 | 16036 | 2270 |
SART1,NIFK,CUL7,FN1,UTP14A,DDX18,SIRT7,NAT10,RSL1D1,CSNK2A1,NOP56,DDX56,MPHOSPH10,EIF2S2,GLYR1,RNF2,NOC3L,FBL,POLR1E,FTSJ3,SNU13,WDR36,DDX24,GNL3,NOL6,UTP15,GNL1,DKC1,PUM3,KPNA1,BMI1,NOLC1,NMD3 |
| 2.108e-07 | -15.37 | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | MSigDB lists | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | 733 | 142 | 17758 | 2279 |
ASCC1,LETM1,LUZP1,GPBP1L1,FANCD2,HECTD3,CCNL2,CUTC,BIRC2,IKZF5,IPP,OGG1,PRKACB,ZBTB17,FBXW4,SESN2,GNL3,TCEB3,PACRGL,NFIA,KIF15,MARCKSL1,SHISA5,DCUN1D5,C10orf76,FOXRED1,CLNS1A,CCDC28B,YTHDF2,C1orf122,SSU72,RAD18,LRRC40,BBIP1,VPS13D,XPNPEP1,RNF214,EPM2AIP1,AK2,LARS2,KHDRBS1,DPF2,ALG8,RSF1,C1orf52,C11orf54,RLF,C1orf50,CHD5,ALKBH8,PIGG,CWF19L2,CPSF3L,SIK3,TIMM8B,KIAA1143,SETD2,MAP7D1,IMPDH2,ARID1A,ARIH2,NCDN,UBE2E1,EXOC6,ATXN7,SPEN,CCDC85B,HMBS,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,GALE,AMOTL1,OSBPL9,UROD,VTI1A,GBF1,FDX1,KDM1A,RPP30,PHC2,PUS3,SETD5,CLCN6,ATRIP,CMPK1,TMEM136,LSM10,NARS2,PCGF3,TMEM123,SLC35F2,UBR4,SMARCC1,HNRNPR,METTL6,ATG7,ZNF436,H2AFX,SLC4A7,NFRKB,ZNF589,RAB30,FGFBP3,CMTM8,TRAK1,SF3A3,MED18,MLH1,MFSD10,MAD2L2,TADA3,SEC24C,IFIT5,ARHGAP1,RDX,DYNC2H1,ERI3,LYPLA2,NUDC,TMEM126B,TMEM126A,ASAP3,SCMH1,ARHGEF12,ARHGAP32,TMEM175,POLR3A,MFN2,RERE,OXSR1,DDX50,ZBTB8OS,HNRNPH3,ATM,ZRANB2,TAF12,RBPJ,GPAM,KIF1B,LRRC41 |
| 2.200e-07 | -15.33 | regulation of biosynthetic process | biological process | GO:0009889 | 4134 | 634 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,ABHD6,NOS1AP,SKI,ZNF37A,TOM1L1,SREBF2,ZFHX3,IKZF5,WIZ,ZNF148,FNIP2,KDM5C,HMBOX1,EIF4E3,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,ZNF197,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,P2RY11,MEF2C,BANP,EPM2AIP1,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ABCA7,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,PDK4,DDR2,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,PDE8B,TAF2,KDM4B,ELP2,PEMT,HIPK2,HOXA3,RPS6KB1,FUS,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,TGFB2,ZNF691,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,ANXA1,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,UQCC1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ZNF124,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,NT5E,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,NTSR1,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,RNF2,ZFP37,ETF1,PRMT3,CTC1,SEC24A,KAT8,KDM3B,PCGF3,DDX41,ENC1,ZNF251,PUM3,EIF3H,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,EIF2B3,ZNF589,PKIB,ZNF507,ESCO1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ZNF594,PTPN2,ZNF561,HIST2H3D,SELT,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,HIST1H4J,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,FNTB,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,PRKAB2,PRKCA,GABPB2,AARS,MGA,LPIN1,GIPR,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,DDAH2,TRRAP,LSM14A,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,LARS2,ZHX3,ANKRD17,CENPB,PID1,GTF2IRD1,CHD5,IGF2BP3,HR,ZNF586,MYC,IGF2BP1,LPCAT1,TERF2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,DHCR7,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,PAIP2,TERF2IP,CHD7,ZNF827,KDM2A,SHC1,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PDK1,MTIF2,SATB2,MED16,PNN,SETD7,SERP1,ERC1,ZBTB25,SNCA,VDR,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,GIGYF2,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,YBX3,ERRFI1,LARP4B,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,IREB2,BRWD3,DDIT3,KAT6A,ZNF76,EIF3C,UBN1,NF1,ATRX,KMT2E,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,YLPM1,JAZF1,GPR87,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,ZBTB17,DEAF1,TRIM13,SESN2,TXLNG,ZNF195,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,SMARCA4,PBX1,PIBF1,ZSCAN5A,RRN3,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,NLN,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,SCARB1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,IGF2BP2,ATF7IP,MED18,SOGA1,BMP6,PRKCH,HAS3,STC2,UTS2,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,EIF5B,CTIF,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,NFKBIB,HRH1 |
| 2.200e-07 | -15.33 | DKC1 (dyskeratosis congenita 1, dyskerin) | protein interactions | 1736 | 89 | 32 | 16036 | 2270 |
BCCIP,NIFK,CUL7,SHQ1,UTP14A,DDX18,CSNK2A1,NOP56,DDX56,MPHOSPH10,SHMT2,DDX31,RNF2,FBL,ZC3H3,FTSJ3,LYPLA2,TERF2,SNU13,WDR36,DDX24,GNL3,ABCF2,DKC1,RBM28,EIF5B,NOP58,PUM3,POLR1C,BMI1,SRP14,NMD3 |
| 2.217e-07 | -15.32 | ATP binding | molecular function | GO:0005524 | 1456 | 256 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,HLTF,PRKCA,AARS,NEK6,SYN2,PDS5B,SUCLG2,DPH6,CHD2,CDK6,KIF15,ABCC2,MCM2,DDX60,DDX3X,DNAH2,RIOK1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,IDH3G,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,MAP2K4,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,ACTR3,PDK4,KIAA0232,OLA1,DDR2,MYH9,CBWD5,HSPA1A,MCM9,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,GALK2,STK10,DHX57,FGFR1,MAT2A,CAMK2D,HIPK2,DNAJA3,CBWD1,RPS6KB1,MDN1,NOLC1,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,RPS6KA5,TTLL11,ABL1,GATC,CBWD6,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,KIF5A,RARS2,TRPM6,CSNK2A1,STK33,MAP2K3,ABL2,DHX33,XRCC2,TRMU,MYH3,SLC27A5,YARS,PRKACB,TRIP13,LONP1,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,TIMM44,KIF16B,PEX1,DYRK1B,HLCS,CHD3,RAD51B,ABCC3,MAGI1,XYLB,SEPHS2,TTN,SARS,AK2,MCM6,TAF1,CLK1,DNAH1,ABCA5,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,BCS1L,OBSCN,LIG4,UBE2E1,DNAH14,ATAD5,IRAK2,DNAH17,HK2,BRSK2,TBCK,DDX10,PAPD4,MYO7A,RIPK1,SMARCA4,DDX60L,DHX35,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,ACSL5,NARS2,SKIV2L,DDX41,NARS,ATP8B2,RAD54B,TPK1,WARS,ATP5D,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,TKFC,VARS,CSNK1A1,PIP4K2A,PRKCH,GART,DDX31,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,PEAK1,PIK3CB,TARS,HSPA1B,ZRANB3,MSH3,RPS6KC1,ZAK,KIF1B |
| 2.239e-07 | -15.31 | WDR36 (WD repeat domain 36) | protein interactions | 134430 | 53 | 23 | 16036 | 2270 |
NIFK,CUL7,DDX18,UBN1,SIRT7,ABCF2,ELP3,UTP15,DKC1,NOP58,USP36,PUM3,NOP56,DDX56,NOL10,MPHOSPH10,DUS3L,RNF2,POLR1B,POLR1C,FBL,TBXA2R,NOLC1 |
| 2.240e-07 | -15.31 | SUMO2 (small ubiquitin-like modifier 2) | protein interactions | 6613 | 200 | 56 | 16036 | 2270 |
CARS,ATRX,ATF7IP,TUBB6,PARN,POGZ,PELP1,HSPA1A,KDM1A,CAD,ZBTB21,BRE,SLX4,PHF5A,USPL1,ATIC,TANK,TRIML2,RNF111,AHCYL1,ZMYM2,ZCCHC7,SOX6,CASP8AP2,MYB,TMPO,GATAD2B,SOBP,MSX1,ZMYM5,CUX1,RANGAP1,VIM,BRCA1,NOP58,UBC,CHAF1A,ZBTB25,ANXA1,PGD,DDX3X,BAZ1A,RANBP2,ATXN7,AHNAK,TP53BP1,CHD3,HIPK2,SENP3,EME1,PSAP,MDN1,BRCC3,IGBP1,ZMAT3,C18orf25 |
| 2.270e-07 | -15.30 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2863 | 452 | 17775 | 2278 |
ARHGAP26,CGN,DCP1B,MKS1,PRKCA,LPAR3,UBR5,GABPB2,RAC3,MGA,PCDH7,PDZD2,MMP7,ZFHX3,ZFYVE28,FAAH2,RABGAP1L,MAD1L1,PDS5B,CHD2,ME1,HRG,CDK6,CNTNAP3B,NRAS,OSBP2,NR6A1,KLHL23,ATG9A,PTPRM,AP4B1,SEMA3F,PLCXD2,OSBPL1A,BRCA2,MPV17,VPS13D,SEMA3C,FIS1,RUNX1,NRP1,RFXAP,SPOCK3,SPOCK2,NMD3,HERC2,DROSHA,CELSR1,ANKRD17,ZHX3,TRIO,NHS,DLGAP4,GTF2IRD1,PID1,SLC1A1,ABCA7,ANXA10,MTUS1,RBM20,PRKCE,NAV1,KIAA1671,USPL1,WDR60,SLC16A9,CCDC88C,CNOT4,FMNL2,GTF2H3,STAG1,PRIM2,KCNQ3,PRDM16,RAPGEF4,TYW1,RYR2,ST6GALNAC3,TPRA1,PLCB1,TRIM37,EVI5,MBNL2,MTR,ATP9B,DYNC1H1,VPS13C,LRP1B,C2orf82,HIF1A,NSF,VCAN,MED15,D2HGDH,RIOK3,DPEP1,KIAA0196,NCOR1,MACROD1,PDLIM5,ARHGAP10,MAP2K4,ZFHX2,COG5,CPT1C,RTTN,TBKBP1,RAB11FIP4,ABCA3,TRPM2,ZNF516,LIN28B,HFM1,KIAA0232,C1QTNF7,VTI1A,CD99L2,SPATS2L,NUP43,PTPRG,PABPC1L,UBL5,PDE3A,RPP30,ZNF827,SLX4,ZSWIM7,ABCA12,TBC1D22A,WAC,NBEA,TTC3,DENND1A,NAA35,C18orf21,ZCCHC14,KMT2D,GON4L,SFXN4,NPM3,WDPCP,SLCO6A1,PREX1,PCNXL2,MARCH6,MEF2D,MEGF11,TTC28,STK10,ERC1,PDE8B,SNCA,DCBLD2,HTR7,ARHGAP21,IQCH,KDM4B,ASTN2,HIPK2,WDR7,LARGE,MDN1,ANXA2,XRCC4,LAMA5,BAG1,COMMD10,SSH2,BRAF,CA11,C10orf2,SESTD1,TCF3,TRAK1,SF3A3,FARS2,SLC25A12,RCAN1,MLH1,KRI1,NEBL,UNC13A,PMPCA,ANXA5,UPF2,C15orf41,SOX6,NAV3,DDHD1,TMC7,WDFY3,POLK,AGPAT4,ARHGAP39,PACS1,R3HDM2,PPIP5K2,UBE2K,PDE3B,CASC1,CCDC150,MRPL36,TRIB3,RETSAT,PXDN,HERC1,ATM,SLCO5A1,SVIL,MYOM2,SORCS2,ANAPC4,GPATCH4,LRRC41,IMMP2L,CUL7,MVK,ATRX,TRPM6,SLC25A21,PLOD1,SEC16A,PCYOX1L,SMARCB1,RTN1,ZNF804A,ABL2,DST,PHKA1,THADA,JAZF1,ANKRD11,MYH3,ANAPC10,GPATCH1,PCOLCE2,HCFC2,LONP1,CEP128,TMPO,FLNC,METTL1,TNK2,CHD9,GPM6A,SLC3A2,TXLNG,HARS,ZNF680,SKIV2L2,ANK2,CDK4,MED27,GPCPD1,NOL6,KSR2,HDAC8,LAMA2,BRCA1,MTHFD1L,FLVCR1,ST3GAL5,CRYBG3,KIF16B,CCDC3,UBTF,TMEM132B,TCF7L1,GATA6,TP53BP1,EEFSEC,CSMD3,ABCC3,PRPF4,DLX2,TSEN2,MAGI1,BEND6,RNF214,DCAF5,USP15,CHMP4C,SLC12A7,XYLB,STX8,FN1,RHOBTB1,ITFG1,STXBP6,NKD2,FAN1,MAPK8IP3,ZIC2,EVPL,ARID1B,DNAH1,ETFB,DOPEY1,RNF40,CEP164,KIAA1958,PPIL2,SEMA3D,VAPB,TIMELESS,CTR9,SYNJ2,GMDS,ZCCHC7,NRIP1,SNX29,NT5E,MTHFD1,RANBP6,KRT20,IFT43,ELOVL6,JMJD1C,ZFP14,BCS1L,WDR25,OBSCN,WWC1,SYT1,AGAP1,DNAH14,NR2F1,VAC14,EXOC6,TBC1D2,GRIK4,UBAP2,BICD1,ATAD5,FSCN1,INTS5,FAT1,DNAH17,SDCCAG8,EXOC4,TMEM117,SLC16A1,CDKAL1,DTD1,KIAA1328,ARHGAP12,DDX10,SH3PXD2A,PDSS2,PDE9A,DMXL2,FEZ2,PAPD4,LPCAT2,RIPK1,ST7L,SSBP2,CSTA,RADIL,PPP1R9A,DDX60L,ZC3H13,BRE,LYPLAL1,NUP133,ARMC5,SNTG2,CCDC40,MYH15,PRMT3,C6orf89,MAML3,TLCD1,PHLDB2,EVL,COL5A2,TFCP2,THSD4,ANKRD33B,R3HDM1,MRRF,SLC35F2,AKAP13,NUP214,EIF3H,ZNF251,TPK1,BTBD11,SLC30A3,CLEC16A,KLF4,CEBPZ,HEATR1,SMG1,PARD3,ATXN7L2,UNC13D,DYM,PDE4B,CLSTN2,PPHLN1,LETMD1,MED18,SEMA3E,MFHAS1,BMP6,PIP4K2A,MRPS11,IQGAP2,PRKCH,PEX7,NDUFV1,SACS,CWC27,PRICKLE2,DDX31,CD44,TTC17,LDLRAD3,DMRT1,C12orf4,HSD17B12,SLC25A1,SLC6A16,MON1A,SCFD2,TOP3A,DHX34,MARS,YIPF3,PDE2A,ZNF407,NAALADL2,CHCHD6,ARMC3,RERE,MKX,CENPP,CTIF,ZRANB3,CDH24,SRBD1,MPP7,TAF4,CUL2,BCAS3,DNAJC12,PREPL,MMP16,MIPOL1,SLC16A10,ZSWIM6 |
| 2.339e-07 | -15.27 | regulation of RNA metabolic process | biological process | GO:0051252 | 3592 | 559 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,NSRP1,ZNF148,FNIP2,KDM5C,HMBOX1,GNL3,EHMT1,NFIA,KRBOX4,RFX2,ZNF197,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,RBM20,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,TASP1,GTF2A1,PDLIM1,EHMT2,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ZKSCAN1,WAC,KMT2D,ZNF480,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,FUS,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,MBNL1,TADA3,SNW1,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,HNRNPLL,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ATF4,AEBP2,ZNF124,PPARG,ZNF414,BAZ2A,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,E2F4,TNFRSF1A,DLX2,BEND6,USP15,FOXO1,CLK1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,TBPL1,ZNF430,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ZFP37,RNF2,AHCYL1,PRMT3,PRPF19,KAT8,KDM3B,PCGF3,DDX41,ZNF251,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,ZNF589,ZNF507,MAP3K13,RFX1,AGO2,FOXP1,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,SNAPC5,TRNP1,ZNF654,SMARCAD1,FOXN3,ZMYM5,DHX34,HIST1H4J,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,GABPB2,MGA,LPIN1,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,SON,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,DROSHA,ZHX3,CENPB,PID1,GTF2IRD1,CHD5,HR,ZNF586,NOVA2,MYC,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,FOSL2,IGSF1,RING1,BLOC1S2,TERF2IP,CHD7,ZNF827,KDM2A,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,SATB2,MED16,PNN,SETD7,ERC1,ZBTB25,SNCA,BAZ1A,VDR,MSX2,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,YBX3,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,POLR2A,ZFP62,ZNF155,BRWD3,DDIT3,KAT6A,ZNF76,KMT2E,ATRX,UBN1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,SRPK2,ZBTB17,DEAF1,TRIM13,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,SUFU,GATA6,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,HEATR1,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,KDM5A,PSPC1,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,ZNF221,HSPA1B,RERE,ZNF708,CUL2,NCBP2,ZRANB2,NFKBIB |
| 2.361e-07 | -15.26 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 690 | 135 | 17758 | 2279 |
TUBE1,CHAC1,PRKCA,SYNJ1,AARS,SLC30A7,PMAIP1,CHD2,ME1,ZMYM2,OGG1,CSGALNACT2,DBN1,SLC3A2,SESN2,RBCK1,BAZ2A,ALDH1L2,GPCPD1,ARRDC3,MCL1,EFHC1,PEX1,SLC7A1,DNAJC1,CTAGE5,ZNF397,CCNB1IP1,NRP1,TNFRSF10D,DCAF5,LPP,CARS,SARS,CELSR1,ITPRIP,SEC24D,C16orf52,TATDN3,FAN1,PHGDH,PDCD5,RHBDD1,NAMPT,DDIT4,SH2B3,C6orf48,SLC7A11,IFRD1,TRA2A,TRAPPC6B,ARRDC4,MBNL2,PGD,MTHFD2,KIAA0355,RIOK3,ZCCHC6,TBL1X,WDR33,SH3PXD2A,N4BP2L2,TCF12,PPDPF,MAP2K5,CYLD,ST7L,SSBP2,FOSL2,CSTA,PAG1,ASNS,JAG1,CCDC50,LPIN2,SLC38A2,RNF2,MAML3,SEC24A,ANTXR2,GARS,TUBA1A,PREX1,LGALS1,ATXN1,GNL1,AKAP13,NHSL1,SETD7,NUP214,TPK1,WARS,BATF3,PLIN2,HIPK2,KLF4,G6PD,ZNF436,ZNF18,CENPBD1,MUTYH,KLHL24,VPS45,LETMD1,ID2,ZNF691,INPP1,RPS6KA5,CSNK1A1,PHLDA2,NEDD4,TANK,STC2,SHMT2,ERRFI1,PCK2,KDM6B,PSAT1,WDFY3,ZMYM5,FRA10AC1,TPM4,PHACTR2,MARS,TRIB3,NOL10,BAZ2B,GADD45A,SRD5A3,MBD6,RPS6KC1,KIF1B,LMBRD2,ZSWIM6,STK4 |
| 2.405e-07 | -15.24 | nuclear speck | cellular component | GO:0016607 | 189 | 50 | 17570 | 2233 |
EP400,THOC5,PRPF31,KMT2E,TFIP11,PLRG1,RCHY1,SF3A3,CCNL2,TRIM22,CSNK1A1,RSRC1,RING1,ZC3H13,ELL,SRSF2,NEK6,PHF5A,NSRP1,YLPM1,WAC,CTR9,NOC3L,NRIP1,SRRM2,OGG1,CDK12,TIMM50,PRPF19,CLK2,MAML3,GATAD2B,RREB1,APEX1,SETD1B,PSPC1,PNN,SON,PLCB1,SPOP,DDX3X,PRPF40B,TOE1,EIF4ENIF1,HIF1A,LUC7L3,FAM206A,PQBP1,PRPF4,MEF2C |
| 2.406e-07 | -15.24 | REGULATION_OF_GENE_EXPRESSION | MSigDB lists | REGULATION_OF_GENE_EXPRESSION | 665 | 131 | 17758 | 2279 |
ZNF76,EIF3C,UBN1,ATRX,PPARGC1B,BCOR,SIRT2,GABPB2,MAP2K3,SMARCB1,SREBF2,ZFHX3,PHF5A,JAZF1,ZEB1,ZNF148,CHD2,HCFC2,CDK6,CARM1,ATF4,NR6A1,PPARG,CDK4,MED27,TCEB3,CUX1,HDAC8,BRCA1,SLC50A1,UBTF,DYRK1B,SUPT4H1,SUFU,GATA6,CHD3,PER1,MKL2,PQBP1,TNFRSF1A,RUNX1,BMI1,EGR1,FOXO1,ZHX3,KHDRBS1,RSF1,SUB1,ZNF354A,VPS72,MYC,BUD31,GTF2H1,TIMELESS,NRIP1,CAMKK2,RREB1,EIF4A2,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,EIF2A,SUPT5H,TCF7L2,MYBBP1A,HIF1A,ZNF254,TCF12,ID1,TRERF1,NPAS2,RBFOX2,PBX1,FOSL2,IGSF1,PAIP2,NRF1,IKBKB,ETF1,MAML3,KAT8,KRT7,TFCP2,EIF3J,MTIF2,ATXN1,POU2F1,ERC1,EIF3H,SMAD3,VDR,RBBP8,ELP2,SMARCC1,KLF4,ARNTL,MED20,HMGA2,MAP3K13,TCF3,TRAK1,ID2,NFX1,IGF2BP2,ATF7IP,TRIM22,AKT1S1,IKBKAP,RPS6KA5,BMP6,FOXO3,ABL1,TADA3,SNW1,PSMG4,SAMD4A,KDM5B,FOXN3,KDM5A,MEN1,POLR3G,NSD1,SRCAP,TBX3,RBPJ,NR2F2,DDIT3,KAT6A |
| 2.434e-07 | -15.23 | WD40_repeat_dom | interpro domains | IPR017986 | 298 | 70 | 18293 | 2341 |
DMXL2,GNB3,PAFAH1B1,WDR74,WDR13,PLRG1,PPP2R2A,NUP43,CORO6,NBEAL1,DENND3,NLE1,AMBRA1,NBEA,PAK1IP1,CORO1A,UTP4,SEH1L,LYST,PRPF19,WDR36,FBXW4,MIOS,WDPCP,ARHGEF10,WDHD1,MED16,SON,UBR4,GEMIN5,WDR5B,ELP2,WDR73,TECPR2,TSSC1,WDR7,IFT140,PRPF4,WDR66,DCAF5,WDR75,PIK3R4,MAPK8IP3,WDR26,WDR37,PEX7,WDR27,WDR60,TENM3,WDR61,WDFY3,TLE3,WDR18,UTP15,WDR25,EIF2A,PWP1,SEC31A,SPAG9,NOL10,PALB2,WDR35,HERC1,BCAS3,APAF1,TBL1X,WDR33,BRWD3,CORO2B,ANAPC4 |
| 2.449e-07 | -15.22 | HALLMARK_MTORC1_SIGNALING | MSigDB lists | HALLMARK_MTORC1_SIGNALING | 198 | 52 | 17758 | 2279 |
ACTR3,SLC2A1,BHLHE40,PHGDH,MAP2K3,DDIT4,NAMPT,EIF2S2,ASNS,IDI1,SLC7A11,UCHL5,GTF2H1,SHMT2,ME1,ETF1,CORO1A,SERPINH1,MTHFD2L,PPA1,HMGCR,FADS1,IFRD1,PDK1,PSAT1,SKAP2,ELOVL6,HSPA5,ABCF2,LDHA,PSMG1,PITPNB,MCM2,CYB5B,SERP1,WARS,POLR3G,RPA1,RDH11,EPRS,TRIB3,HPRT1,MTHFD2,INSIG1,COPS5,G6PD,HK2,SQLE,HMBS,NFKBIB,DHCR7,DDIT3 |
| 2.609e-07 | -15.16 | HELICc | smart domains | SM00490 | 106 | 35 | 9131 | 1249 |
ATRX,DDX18,HFM1,DDX19A,SMARCA4,HLTF,DHX35,CHD5,DDX60L,CHD7,DDX56,DHX37,DHX33,CHD2,DDX31,SKIV2L,CHD9,DDX28,DDX24,DDX41,SKIV2L2,SMARCAD1,EIF4A2,DHX34,DDX60,DDX49,DHX57,RAD54B,ZRANB3,DDX3X,SRCAP,ASCC3,DDX50,CHD3,DDX10 |
| 2.694e-07 | -15.13 | MARSON_BOUND_BY_FOXP3_STIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_STIMULATED | 962 | 177 | 17758 | 2279 |
SLC37A3,LYRM4,PRDX6,TRIM16,RCHY1,IKBIP,SNAPC4,RAP1A,RABGAP1L,LETM2,ANAPC11,UBAP2L,JOSD1,ME1,POLR3B,KDM5C,SRRM2,SRPK2,SLC3A2,SESN2,RNMT,CDK4,AP4B1,TCEB3,MINA,NFIA,ATG12,MCL1,SHISA5,BRCA1,DENND4A,SKIL,EIF4ENIF1,TOM1L2,HLCS,INSIG1,PER1,HSPBAP1,ARL6IP5,FIP1L1,NRP1,BMI1,SARS,EPM2AIP1,ITPRIP,ALG8,HSD17B10,PRAF2,SMAD7,SMG7,ZFP36L1,DDIT4,FKBP1A,SH2B3,RSPRY1,FAM192A,ELL,ENTPD5,VPS72,MYC,WDR60,SYNJ2,PRMT5,NRIP1,POLR1E,TOMM34,NT5E,PPAT,TLE3,ARID5B,USP10,ARID1A,ANGPTL4,ARIH2,SPAG9,FAM135A,SERF2,SIL1,ARHGAP12,TBL1X,ARHGAP10,SPRED2,ASH1L,CYLD,CCDC58,ZBTB37,RPS29,SLC2A1,OSBPL9,COBLL1,NUP43,POP5,EEA1,PAIP2,RIOK2,FLAD1,CAD,BRE,SHC1,ARMC6,UBR1,SETD5,INTS12,ETF1,CMPK1,AHCYL1,LSM10,NARS2,PMS1,ANTXR2,PDK1,PCMT1,ATXN1,ATP6V0A1,TOR1AIP2,MARCH6,GSTCD,SETD7,POLG2,ARL5B,ZBTB25,PLIN2,GNG2,SMARCC1,KPNA3,METTL6,CEBPZ,XRCC4,DNAJC2,MINK1,SUPT6H,NSUN6,DBF4,LETMD1,SLC25A12,FARS2,MYNN,WDR26,JMJD6,MLH1,RPS6KA5,BZW2,MBNL1,C15orf57,SFR1,ANXA7,LRP2BP,DSG2,PMPCA,COPS7B,LYPLA2,TSHZ1,MARCH9,KDM5B,KDM5A,ANKMY2,SCFD2,C11orf49,ARHGEF12,CCDC113,HIST1H4J,KLF6,PEAK1,NOP58,SLC23A2,MRPL36,SERINC1,ZNF330,HERC1,ORC5,VPS37B,MSH3,CSRNP1,ATM,APAF1,RBPJ,MTMR1 |
| 2.728e-07 | -15.11 | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP | MSigDB lists | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP | 188 | 50 | 17758 | 2279 |
SERINC5,SHQ1,TTC27,NFX1,RSL1D1,PLA2G12A,NUP160,RPP30,SRPRB,RRN3,SACS,MPHOSPH10,PSMG4,IKZF5,TMEM161A,ZNHIT6,MYC,TRIAP1,AKAP11,SNAPC5,NARS2,GNL3,EIF3J,SCFD2,WBSCR22,BMS1,DKC1,C8orf33,ODC1,MTR,CLNS1A,BTBD11,ATXN7,VPS13C,FBXO21,ARHGAP21,TASP1,FAM135A,DCXR,KIAA0355,HNRNPH3,DPP4,TSEN2,EIF2B3,TATDN1,NOLC1,C12orf45,MUTYH,GPATCH4,TMCC1 |
| 2.728e-07 | -15.11 | GCM_RAN | MSigDB lists | GCM_RAN | 188 | 50 | 17758 | 2279 |
HERC2,SNX27,ASCC1,ANKRD17,ATP6V1A,TMEM183A,MAPK8IP3,FAN1,KIF5C,RTN4,ATG2B,IKBKAP,ABHD6,FOXO3,FAM8A1,POGZ,SPIRE1,NUP133,DCTN4,VPS52,RAN,ZNF710,KDM3B,FADS1,CHD9,SIK3,TSPYL4,STAMBP,ZFP14,PTK2,UBE2K,TRIM37,GZF1,TAF9B,RERE,FBXO21,EIF4ENIF1,SPAG9,KIDINS220,TMEM237,KPNA3,LEMD3,CLEC16A,LARGE,RBPJ,PREPL,BRD9,TBCK,XPO6,KIF1B |
| 2.902e-07 | -15.05 | regulation of metabolic process | biological process | GO:0019222 | 6593 | 964 | 16441 | 2138 |
ARHGAP26,ASCC1,THOC5,DCP1B,SBF2,CHAC1,HLTF,CCNL2,ZNF44,NUP160,ABHD6,LPAR3,AMBRA1,NOS1AP,SKI,ZNF37A,TOM1L1,NEK6,SREBF2,IKZF5,ZFHX3,PMAIP1,NSRP1,RABGAP1L,MAD1L1,WIZ,ZNF148,FNIP2,KDM5C,HRG,ZNRD1,FXN,CDK6,HMBOX1,EIF4E3,NRAS,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,C5AR1,DCUN1D5,SLC50A1,ZNF197,STOML2,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,MPV17,FIS1,DIRAS1,RUNX1,TPM1,ZNF532,P2RY11,MEF2C,BANP,HERC2,TNNC1,EPM2AIP1,TRIP6,SLK,KHDRBS1,TRIO,SIRT7,PIK3R4,RSF1,PARN,CDC73,ABCA7,CHN1,RBM20,CNST,UBE3A,APLF,ZNF326,MED24,ANP32B,CCDC88C,PRMT5,ZNF518B,MAP3K12,PABPC1,SERBP1,MYB,HMGCR,PEA15,ZNF675,GATAD2B,FADS1,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,USP10,SMARCD3,ARRDC4,EVI5,CPT1A,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,KPNA1,GTF2A1,PDLIM1,RPL28,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,ARHGAP10,SGSM3,SPRED2,MAP2K5,ZNF516,TRERF1,GTF2H2C,PAFAH1B1,NPAS2,PDK4,DDR2,MYH9,AGAP6,NUP43,SAFB2,HSPA1A,TMEM150C,ACD,ERI1,TBC1D22A,ZKSCAN1,WAC,MMP14,PXK,ZC3H3,DENND1A,PERP,KMT2D,ZNF480,EIF3J,ATF7IP2,ARHGEF10,MEF2D,FGFR1,PDE8B,TAF2,FBXL5,ARHGAP21,CDC16,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,MAPT,COMMD10,HMGA2,ZNF786,SERINC5,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,AKT1S1,TRIM22,BHLHE40,RNASEH2B,ZNF691,TGFB2,PSMF1,MBNL1,POM121,TADA3,SNW1,NPRL2,GATC,SUV39H2,TAF3,ACAP3,ANXA5,RAPGEFL1,ARHGAP1,ZNF710,SAMD4A,SOX6,SPTAN1,FGF9,USP42,NXN,IL6R,ZNF467,UBE2K,PDE3B,FOXC1,UBC,ANXA1,OXSR1,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,HERC1,PSAP,BMP4,IGBP1,UQCC1,DOCK6,ANAPC4,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,FAM13A,NLE1,BIRC2,GIT2,HNRNPLL,MAP2K3,ABL2,ECM1,SRSF2,PHF5A,ARHGAP18,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SLC25A23,TMPO,CDC37,PTPRK,CHD9,RBCK1,ZNF124,GCNT2,AEBP2,ATF4,PPARG,BAZ2A,ZNF414,CDK4,ANK2,HSPA5,TSN,MED27,GMFB,SUMO3,BRCA1,ODC1,ZNF91,MLLT10,KIF16B,DYRK1B,HPRT1,TCF7L1,ZNF622,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,SOCS4,TNFRSF1A,SGSM2,ADAM9,DLX2,BEND6,UQCC2,USP15,TTN,FOXO1,CLK1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,HES6,ZFP36L1,BARX2,ZIC2,TRIM15,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,NDRG4,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,WNT16,LRSAM1,NT5E,CAMKK2,PAXBP1,CRADD,USP49,TLE3,SETD2,UTP15,RNH1,OBSCN,MEX3B,SUPT5H,VAC14,NR2F1,TCF7L2,TBC1D2,ATXN7,SPAG9,SYNCRIP,IRAK2,TBPL1,SIL1,ZNF430,PPP1R12B,DTD1,ARHGAP12,BRSK2,TESC,PRKAR2A,BCCIP,USP7,ID1,CYLD,UPK3B,ARID2,RBFOX2,NTSR1,PPP2R2A,RIPK1,ZNF83,SSBP2,ZNF709,DENND3,PELP1,ZNF121,PLXNB1,KDM1A,ZBTB21,NRF1,JAG1,NUP133,GRIN2C,DNAJB6,IKBKB,RNF2,ETF1,ZFP37,AHCYL1,SPIDR,PRMT3,CASP10,CTC1,PRPF19,SEC24A,KAT8,KDM3B,ARHGAP17,PCGF3,DDX41,KIRREL2,RAB7A,C1QTNF1,VIM,AKAP13,ENC1,NUP214,ZNF251,PUM3,EIF3H,USP36,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,PUS1,ZNF18,MED20,EIF2B3,ZNF589,PKIB,PARD3,ZNF507,NIFK,ESCO1,MINK1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ANKRD54,ZNF594,IQGAP2,PTPN2,ANXA7,ZNF561,TMEM161A,HIST2H3D,SELT,POLR1B,FBXO31,CD44,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,TEX14,DHX34,RAP1GDS1,RANGAP1,ARHGEF12,HIST1H4J,PIK3CB,POLR3A,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,TBX3,SET,CSRNP1,MSH3,GLG1,BCAS3,EIF2S1,FNTB,USP20,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,CUL4A,PRKAB2,PRKCA,GABPB2,AARS,UBR5,LPIN1,MGA,GIPR,S100A10,ZFYVE28,RNF111,ME1,CHD2,MEIS3,SEH1L,ZNF646,TBC1D8,DDN,DPF3,SETD1B,NR6A1,EYA3,TCEB3,CUX1,SUPT20H,SON,DENND4A,SAP30BP,SPOP,DOT1L,GZF1,SKIL,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,ARL6IP5,ZNF81,HIC2,TNFRSF10D,NRP1,BMI1,RFXAP,SPOCK3,PTPN14,WDR75,IFT57,DROSHA,EGR1,JUP,CDC42EP2,ANKRD17,LARS2,ZHX3,OPHN1,CENPB,GTF2IRD1,PID1,TGFBR2,PDCD5,CHD5,IGF2BP3,FKBP1A,PRKCE,HR,ZNF586,ENTPD5,NOVA2,ASAP1,MYC,IGF2BP1,LPCAT1,CAV2,TERF2,ADARB1,EXOSC2,SYNGAP1,RREB1,POLA1,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,NELFA,PLCB1,ZNF850,ANGPTL4,ARIH2,PHF6,ZNF425,CAT,ASCC3,EPRS,KIDINS220,ALKBH3,NSF,HIF1A,PMEPA1,SPEN,MED15,ZBTB12,PURB,DPEP1,NCOR1,IQSEC2,DHCR7,SMYD3,ZFHX2,ZNF254,PTCD2,BIRC6,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,PAIP2,BLOC1S2,TERF2IP,CHD7,ZNF827,SLX4,SHC1,KDM2A,PPID,UCHL5,LPIN2,SOCS6,DTNBP1,SSBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PDK1,MTIF2,PREX1,DLG4,SATB2,MED16,PNN,SETD7,TBC1D16,STK10,ERC1,SERP1,SNCA,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,ALKBH1,TRAF3,ANXA2,TBXA2R,SETD6,XRCC4,MID1,NOSTRIN,NCOR2,BRAF,TCF3,ZNF280C,NFX1,RCAN1,MYNN,MLH1,MON2,IKBKAP,NOL3,RPS6KA5,GIGYF2,PHLDA2,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,RGS17,PTRF,ELP5,TRIAP1,RDX,CELF1,EXOSC4,YBX3,LARP4B,ERRFI1,MAP3K14,PLEKHG4,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,PXN,APEX1,WDFY3,ZFYVE1,KCNMA1,PTK2,KLF6,GUF1,POLR2A,ZFP62,KLHL22,IREB2,ZNF155,ATM,APAF1,PGAM5,BRWD3,RABEP1,DDIT3,KAT6A,STK4,ZNF76,EIF3C,UBN1,ATRX,NF1,KMT2E,PTPRA,RCHY1,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,ANAPC1,RAP1A,YLPM1,JAZF1,GPR87,ANAPC11,ANAPC10,RELB,ZEB1,PCOLCE2,SLC35C2,HCFC2,OGG1,TRIP13,PRKACB,TRIM14,CARM1,SRPK2,ELOF1,ZBTB17,DEAF1,TNK2,TRIM13,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,TFPI,ARRDC3,MINA,HDAC8,CAV1,KMT2C,ZSCAN2,SOX4,SERGEF,YTHDF2,TAF9B,PAF1,UBTF,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CTAGE5,CLU,ZC3H8,ZNF397,NOCT,DMTF1,MTCH1,EMSY,TNRC6A,FN1,TAF1,PAX2,DPF2,UBXN1,MED13L,SMG7,PHGDH,RHBDD1,NAMPT,DDIT4,TOX4,RNF141,ELL,P3H1,SIPA1L3,ZNF354A,ATXN2,BUD31,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,XPO5,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,AGAP1,HERPUD1,ISG15,UBE2E1,APBB3,BICD1,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,FEZ2,CELSR3,CEMIP,TNXB,SMARCA4,PBX1,PIBF1,CSTA,GBF1,ZSCAN5A,RRN3,MPHOSPH10,BRE,SOCS1,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,HTRA2,AUP1,MOSPD1,MAML3,TMLHE,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,NLN,ATXN1,POU2F1,TOR1AIP2,EDEM2,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,COPS5,ZNF557,ARNTL,CEBPZ,DUSP19,SRFBP1,HEATR1,SCARB1,NFRKB,USP11,BRD9,DNAJC2,TNIK,SH2D3A,SUPT6H,CAMK1,H2AFJ,DBF4,PPHLN1,MED18,IGF2BP2,ATF7IP,CHCHD10,PPP1R1C,SOGA1,PIP4K2A,BMP6,SFI1,PRKCH,HAS3,STC2,LDLRAD3,UTS2,AMOT,DMRT1,PKNOX1,TOP1,RPS6KB2,KDM6B,ARNTL2,PPP1R9B,DNMBP,MSX1,KDM5B,FGF2,CRIM1,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ASAP3,SCMH1,ZNF324B,PHACTR2,ARHGAP32,PDE2A,MEN1,EIF5B,ZNF407,SYMPK,RERE,ZNF221,CTIF,HSPA1B,ZNF708,SERINC1,GADD45A,CUL2,ZRANB2,NCBP2,POLR1C,NFKBIB,ZAK,MMP16,ARHGAP27,HRH1 |
| 2.912e-07 | -15.05 | KRIGE_AMINO_ACID_DEPRIVATION | MSigDB lists | KRIGE_AMINO_ACID_DEPRIVATION | 28 | 15 | 17758 | 2279 |
CARS,SARS,TRIB3,SESN2,ASNS,GADD45A,PSAT1,SLC7A11,STC2,SLC38A2,MARS,CHAC1,DDIT3,WARS,DDIT4 |
| 2.960e-07 | -15.03 | regulation of cellular biosynthetic process | biological process | GO:0031326 | 4091 | 627 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,NOS1AP,SKI,ZNF37A,TOM1L1,SREBF2,ZFHX3,IKZF5,WIZ,ZNF148,FNIP2,KDM5C,HMBOX1,EIF4E3,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,ZNF197,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,P2RY11,MEF2C,BANP,EPM2AIP1,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ABCA7,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,PDK4,DDR2,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,PDE8B,TAF2,KDM4B,ELP2,PEMT,HIPK2,HOXA3,RPS6KB1,FUS,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,ANXA1,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,UQCC1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ZNF124,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,NTSR1,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ZFP37,RNF2,ETF1,PRMT3,CTC1,KAT8,KDM3B,PCGF3,DDX41,ENC1,ZNF251,PUM3,EIF3H,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,EIF2B3,ZNF589,PKIB,ZNF507,ESCO1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ZNF594,PTPN2,ZNF561,HIST2H3D,SELT,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,HIST1H4J,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,EIF2S1,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,PRKAB2,PRKCA,GABPB2,AARS,MGA,LPIN1,GIPR,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,DDAH2,TRRAP,LSM14A,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,LARS2,ZHX3,ANKRD17,CENPB,PID1,GTF2IRD1,CHD5,IGF2BP3,HR,ZNF586,MYC,IGF2BP1,LPCAT1,TERF2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,ZNF425,CAT,ASCC3,EPRS,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,PAIP2,TERF2IP,CHD7,ZNF827,KDM2A,SHC1,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PDK1,MTIF2,SATB2,MED16,PNN,SETD7,SERP1,ERC1,ZBTB25,SNCA,VDR,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,GIGYF2,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,YBX3,ERRFI1,LARP4B,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,GUF1,POLR2A,ZFP62,ZNF155,IREB2,BRWD3,DDIT3,KAT6A,ZNF76,EIF3C,UBN1,NF1,ATRX,KMT2E,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,YLPM1,JAZF1,GPR87,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,ZBTB17,DEAF1,TRIM13,SESN2,TXLNG,ZNF195,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TNRC6A,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,PBX1,SMARCA4,PIBF1,ZSCAN5A,RRN3,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,NLN,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,SCARB1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,IGF2BP2,MED18,SOGA1,BMP6,PRKCH,HAS3,STC2,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,EIF5B,CTIF,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,NFKBIB,HRH1 |
| 3.027e-07 | -15.01 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4587 | 687 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,HLTF,SLC6A8,NUP160,SYNJ1,AMBRA1,NOS1AP,SKI,PCDH7,PDZD2,MMP7,NEK6,PMAIP1,THAP4,FAAH2,RABGAP1L,RASSF3,MAD1L1,KDM5C,FXN,AVEN,CDK6,NRAS,PTPRM,C11orf80,AKAP12,MCL1,MCM2,ZNF197,DDX3X,AHNAK,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,ABCA7,CHN1,SH2B3,DDX56,UBE3A,DHX37,SLC38A5,MCM5,ANP32B,GEMIN4,MAP3K12,MYB,HMGCR,PEA15,ZNF675,GTF2H3,STAG1,PRDM16,EIF4A2,RYR2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,IRS1,LRP1B,KPNA1,EHMT2,TRAP1,SURF1,GPN1,ARHGAP10,SPRED2,DNM3,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,MMP14,MSH4,TRMT12,PMS1,KMT2D,FAM111B,ARHGEF10,ADAM32,MEF2D,FKBP3,FGFR1,GNG2,TAF2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,HIPK2,RPS6KB1,FUS,BRCC3,ZBTB11,BAG1,RAB30,TRIM36,HMGA2,XPC,SESTD1,ID2,GAS6,IP6K2,POM121,TADA3,SNW1,SUV39H2,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,ARHGAP39,LDHA,IL6R,DDX49,FOXC1,ANXA1,RPA1,OXSR1,TRIB3,POLE2,HERC1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,WDR13,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,PHKA1,DHX33,XRCC2,NCKIPSD,ANKRD11,RAN,POLE3,ZMYM2,ETV1,PTPRK,VPS13B,FMNL3,CHD9,CDK4,TSN,HSPA5,GMFB,COL4A3BP,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,ARL4A,E2F4,PER1,TECPR2,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,NKD2,SMAD7,LAMTOR3,MEX3A,HSD17B10,MAPK8IP3,HES6,RNF40,ZNF358,CEP290,PDE10A,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,CRADD,SETD2,OBSCN,MEX3B,ZNFX1,NR2F1,VAC14,SPAG9,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,USP7,SART1,ID1,ARID2,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,PPP1R9A,SEMA6A,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,CORO1A,AKNAD1,IPO11,CASP10,KDM3B,SKIV2L,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,AUH,MAP3K13,APRT,FOXP1,CSNK1A1,PTPN2,ADH5,FAM50A,SACS,SURF2,DDX31,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,TPM4,TEX14,TOP3A,DHX34,PEAR1,RAP1GDS1,ARHGEF12,PALLD,PIK3CB,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,KIF1B,MYCBP2,POLB,CGN,CUL4A,PRKAB2,TNFRSF21,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,LPIN1,MGA,SUCLG2,CHD2,FAM127A,SETD1B,NOL8,GNG7,ZDHHC14,DENND4A,PLCXD2,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,IFT57,DROSHA,JUP,EGR1,ANKRD17,ST6GAL1,CENPB,OPHN1,SSR4,TGFBR2,PDCD5,CHD5,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,SAMD13,IGF2BP1,PRPS1,TERF2,SIK3,DDX28,RREB1,PRIM2,ANAPC13,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,RABAC1,ARID1A,PLCB1,PHF6,CAT,HIF1A,PMEPA1,VCAN,SPEN,RIOK3,UMPS,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,BIRC6,PTPRG,RING1,IGSF1,PHC2,NUBPL,TERF2IP,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,RFC3,BRD4,PDK1,PREX1,POLG2,STK10,ERC1,DHX57,BAZ1A,CAMK2D,SMARCC1,G6PD,DNAJA3,FTSJ1,H2AFX,ACP1,ALKBH1,TRAF3,MDN1,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,NOL3,IKBKAP,DNAJC22,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,RDX,COPS7B,NLGN3,S100A14,CLK2,NAV3,PXN,APEX1,FZD3,ADSL,BMS1,FBXO21,HELZ,ORC5,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,PIGM,PHF3,NF1,ATRX,PTPRA,FANCD2,TRPM6,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,DST,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,ANAPC10,RELB,YARS,OGG1,TRIM14,PRKACB,CARM1,SRPK2,TNK2,SESN2,TRIM13,FBXW4,TXLNG,SIRT6,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,SOX4,SERGEF,TAF9B,GEMIN5,RHOU,SUFU,DNAJC1,PQBP1,CSMD3,ASB3,CLU,EME1,ZC3H8,COPS6,DCAF5,MTCH1,FBXO45,AK2,PIGN,RHOBTB1,TAF1,PCSK7,MED13L,XPO7,DDIT4,RNF141,ELL,N4BP2,AKAP11,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,SYT1,UBE2E1,HK2,TBL1X,TBCK,FNBP1L,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,PBX1,DHX35,RIOK2,BRE,SOCS1,NVL,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,ITGAX,MET,GNG5,AUP1,MOSPD1,TMLHE,PARP2,METTL2A,ATXN1,DKC1,UBR4,RAB10,RAD54B,TPK1,IKZF4,KPNA3,COPS5,DUSP19,FKBP5,DISP1,SCARB1,RNF130,USP11,SMG1,TMCC1,DNAJC2,BCKDK,TNIK,DNAJA4,SH2D3A,DYM,CAMK1,DBF4,MED18,ATF7IP,IGF2BP2,PPP1R1C,FAM49A,PIP4K2A,MAN1A1,PRKCH,CTNNBL1,SEC24C,TANK,AMOT,RPS6KB2,TOP1,KDM6B,ARNTL2,DNMBP,IL11RA,GPHN,FGF2,KDM5A,SCFD2,MARS,ARHGAP32,TMEM187,NAPEPLD,GADD45A,CUL2,NFKBIB,ZAK,MMP16 |
| 3.192e-07 | -14.96 | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | 1176 | 209 | 17758 | 2279 |
SLC37A3,GGT1,ASCC1,LYRM4,PRDX6,TRIM16,ACTG1,AMBRA1,WNT2B,SLC30A7,YLPM1,DHX33,UBAP2L,MAD1L1,ME1,POLR3B,KDM5C,TMPO,SRPK2,EIF4E3,RNMT,AP4B1,TCEB3,GMFB,KIF15,NFIA,ATG12,SHISA5,PITPNB,HIST1H2BL,TOM1L2,INSIG1,DNAJC1,LSM14A,NSMCE1,ARL6IP5,ARL4A,ASB3,RIOK1,SEPHS2,AK2,ITPRIP,CLK1,VTA1,PRAF2,SMAD7,ZFP36L1,CCDC47,XPO7,TGFBR2,CD226,DDIT4,ABCA7,FKBP1A,RSPRY1,FAM192A,ELL,SUB1,ENTPD5,APLF,MYC,WDR60,MED24,GMDS,PRMT5,CWF19L2,POLR1E,PRPS1,TOMM34,PABPC1,NT5E,SIK3,KIAA1143,TLE3,TRA2A,ELP3,ARID5B,HAUS6,ARID1A,CPT1A,SLC26A11,PHF6,CAT,MTHFD2,CDK9,ARHGAP12,TBL1X,NCOR1,ARHGAP10,SMYD3,RWDD1,PAPD4,FAM207A,RPS29,ACTR3,PPP2R2A,RIPK1,LPCAT3,NUP43,FOSL2,EEA1,SLC39A1,NDUFB3,FLAD1,BRE,SHC1,ARMC6,UBR1,DNAJB6,SETD5,WAC,GARS,PDK1,WDPCP,PCMT1,R3HDM1,ATXN1,ATP6V0A1,TOR1AIP2,MED16,MARCH6,SLC35D1,POLG2,STK10,EIF3H,ZBTB25,SMAD3,PES1,GNG2,RANBP2,CAMK2D,SMARCC1,KPNA3,ATG7,XRCC4,PPIL3,MORC2,MINK1,MCM10,ARL15,SESTD1,H2AFJ,DBF4,VPS45,FARS2,ID2,MYNN,WDR26,ATF7IP,JMJD6,MLH1,AKT1S1,CSNK1A1,INPP1,RPS6KA5,FOXO3,BZW2,MBNL1,PTPN2,KRI1,ANXA7,LRP2BP,STC2,SHMT2,COPS7B,RDX,ARHGAP1,EXOSC4,CPNE7,MAP3K14,FBL,LDLRAD3,MBTPS2,TSHZ1,VPS37A,DNMBP,DDX24,KDM5B,KDM5A,ANKMY2,TPM4,NXN,SCMH1,C11orf49,ARHGEF12,CCDC113,PTK2,HIST1H4J,FAM126B,KLF6,PEAK1,ECH1,POLR2A,ZRANB3,KISS1R,HELZ,STX1A,ARID3B,HERC1,ORC5,VPS37B,MSH3,EIF2S1,FNTB,ATM,RBPJ,ZAK,STK4,LRRC41 |
| 3.454e-07 | -14.88 | tRNA processing | biological process | GO:0008033 | 141 | 41 | 16441 | 2138 |
CTU2,SARS,AARS2,LAGE3,HSD17B10,FARS2,POP5,NUP43,NUP160,AARS,POM121,RPP30,PUS3,DUS4L,NUP133,TRMT13,TRMU,ALKBH8,RAN,FBL,TRMT10A,TRMT12,SEH1L,METTL1,ELP3,TYW1,METTL2A,NUP214,PUSL1,POP1,EPRS,RANBP2,DUS3L,TRMT5,ZBTB8OS,ADAT2,FTSJ1,CDKAL1,PUS1,TSEN2,METTL2B |
| 3.572e-07 | -14.84 | MODULE_35 | MSigDB lists | MODULE_35 | 16 | 11 | 17758 | 2279 |
CARS,EPRS,SARS,GARS,NARS,HARS,LARS2,HARS2,VARS,YARS,AARS |
| 3.750e-07 | -14.80 | TRANSCRIPTION | MSigDB lists | TRANSCRIPTION | 740 | 142 | 17758 | 2279 |
ZNF76,UBN1,ATRX,PPARGC1B,BCOR,SIRT2,SNAPC4,GABPB2,MAP2K3,SMARCB1,SREBF2,ZFHX3,PHF5A,JAZF1,ZEB1,ZNF148,CHD2,ETV1,HCFC2,TRIP13,CARM1,DEAF1,ATF4,NR6A1,PPARG,MED27,TCEB3,CUX1,HDAC8,BRCA1,UBTF,SKIL,DYRK1B,SUPT4H1,SUFU,GATA6,CCNT1,CHD3,PER1,MKL2,PQBP1,TNFRSF1A,RUNX1,EGR1,FOXO1,ZHX3,KHDRBS1,PAX2,RSF1,SUB1,ELL,ZNF354A,VPS72,MYC,BUD31,GTF2H1,TIMELESS,MED24,NRIP1,POLR1E,CAMKK2,RREB1,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,SUPT5H,TCF7L2,PWP1,MYBBP1A,HIF1A,CDK9,NCOR1,ZNF254,TCF12,ASH1L,ID1,TRERF1,NPAS2,RBFOX2,PBX1,FOSL2,IGSF1,NRF1,RRN3,IKBKB,MAML3,KAT8,TFCP2,ATXN1,POU2F1,MED16,ERC1,BATF3,TAF2,SMAD3,VDR,RBBP8,ELP2,SMARCC1,COPS5,KLF4,ARNTL,CEBPZ,MED20,NFRKB,TROVE2,HMGA2,MAP3K13,TCF3,TRAK1,ID2,NFX1,ATF7IP,TRIM22,IKBKAP,RPS6KA5,BMP6,FOXO3,ABL1,TADA3,SNW1,PSMG4,PTRF,SNAPC5,APEX1,KDM5B,FOXN3,KDM5A,MEN1,POLR3G,NSD1,SRCAP,TBX3,RBPJ,NR2F2,POLR1C,NFKBIB,DDIT3,KAT6A |
| 3.957e-07 | -14.74 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 10319 | 1431 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MKS1,TUBE1,CCNL2,SLC6A8,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,AP1M1,MAD1L1,KDM5C,SRRM2,PPM1K,CCDC57,NRAS,EHMT1,AP4B1,NFIA,KIF15,C5AR1,WDHD1,ABCC2,MCM2,ZNF197,AHNAK,RAD18,LRRC40,SYNGR2,BDH2,DIRAS1,RIOK1,RUNX1,TPM1,ZNF532,BANP,TMEM63C,TRIO,PIK3R4,BTBD9,PDCD7,CDC73,PITPNM1,CHN1,UBE3A,DHX37,MED24,GEMIN4,MRPL21,PABPC1,SAMD3,MYB,GATAD2B,ZNF675,STAG1,ALG6,WDR61,KCNQ3,USP10,ST6GALNAC3,SNAP25,TRIM37,USP46,IRS1,DYNC1H1,KPNA1,GSTO2,RPL28,EHMT2,TRAP1,KIAA0196,ARHGAP10,SGSM3,SDSL,RAB11FIP4,MAB21L3,DDR2,CD99L2,FAM122B,ISG20L2,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,ZBED2,CD96,ACD,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,MEF2D,KCNH3,SLC35D1,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,NSMCE2,CAMKMT,HOXA3,RPS6KB1,CENPBD1,METTL2B,CATSPERG,BAG1,MAPT,RAB30,HMGA2,XRRA1,ATG2B,GAS6,IP6K2,TAF3,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,FBXL19,C15orf41,SAMD4A,PNMA1,SPTAN1,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,RSBN1,CCDC113,PPIP5K2,ANXA1,OXSR1,NSD1,SRCAP,HERC1,AEN,BMP4,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,METTL8,TRIML2,ZMYM2,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,LAMA2,KCNH2,DLST,CRYBG3,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,LSS,CHD3,ARL4A,E2F4,DPP4,ADAM9,PPP3CC,MAGI1,USP15,FOXO1,CLK1,ITFG1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ARID1B,SPIRE1,MBD2,VPS72,VAPB,CTR9,WNT16,LRSAM1,CWF19L2,USP49,SETD2,OBSCN,MAPK1IP1L,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,PTP4A2,DDX10,SH3PXD2A,USP7,SART1,ID1,ARID2,SLC48A1,NTSR1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,DDX60L,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,VIM,CA5B,EIF3H,TJAP1,EXO1,LMBR1L,KLF4,MED20,MUTYH,PARD3,ZNF507,MCM10,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,ADH5,SURF2,TMEM161A,POLR1B,C12orf4,AP4S1,LRRIQ1,FOXN3,SMARCAD1,ABCF2,TOP3A,ARHGEF12,PALLD,SMPDL3B,POLR3A,DKK1,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,USP20,RBM26,RBPJ,NR2F2,XPO6,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,ZNF646,ACADS,FAM127A,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,DENND4A,SON,DDX60,PLCXD2,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,SH3RF1,CCNT1,HSPBAP1,LUC7L3,XPNPEP1,NRP1,TNFRSF10D,BMI1,SPOCK3,ZMAT3,NMD3,PRPF38B,C9orf78,JUP,PRPF31,ST6GAL1,DLGAP4,CENPB,PRPF39,SSR4,PDCD5,FAM192A,TECTA,HR,NOVA2,USPL1,MYC,FDFT1,RREB1,PRIM2,ANAPC13,PCCA,RAPGEF4,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,MTR,SLC26A11,PHF6,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,VMA21,BIRC6,KIAA0232,PLEK2,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NUBPL,DECR1,SLX4,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,TTC3,CDK12,SAP30,BRD4,PREX1,LRRC8A,GNL1,SATB2,MARCH6,ERC1,ZBTB25,BAZ1A,CAMK2D,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,SLC4A7,TRAF3,XRCC4,MID1,SSH2,NOSTRIN,BRAF,KIF5C,DNAJC22,OPA1,INPP1,GIGYF2,ABL1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,CLK2,TMC7,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,ADSL,PACS1,BMS1,KLF6,INF2,RETSAT,IREB2,ORC5,ATM,SVIL,APAF1,ADK,IPO4,DDIT3,IMMP2L,PIGM,ZNF76,ATRX,RARS2,SLC30A7,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CEP128,SRPK2,DTNB,TNK2,DEAF1,FBXW4,SESN2,SKAP2,SIRT6,ARRDC3,VWCE,MINA,KSR2,COTL1,PITPNB,MTHFD1L,SGK2,KMT2C,TIMM44,HLCS,CC2D1B,CTAGE5,CSMD3,ASB3,EME1,CLU,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,UBXN1,PCSK7,QSER1,RNF141,ELL,WDR27,PRF1,ZCCHC7,LRP3,AKAP11,MTHFD1,MSI2,ZNF234,HBG2,PPAT,XPO5,ELP3,JMJD1C,ZBED4,LIG4,CORIN,SYT1,AGAP1,UBE2E1,MGAT2,SYCP2L,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,TCF12,DMXL2,SNX27,DLL4,PSTPIP2,TNXB,PIGH,SMARCA4,PBX1,TBCCD1,COBLL1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,SOCS1,PPFIBP1,FHIT,ADCK4,ITGAX,VCL,C6orf89,GNG5,MAML3,NARS2,RTN4RL2,PRAME,GRHL3,METTL2A,ATXN1,MRRF,DKC1,UBR4,ARMC4,KPNA3,IKZF4,DUS3L,HNRNPR,ZNF557,DUSP19,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,WDR26,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,MFHAS1,FAM49A,GFM2,STC2,LDLRAD3,ERI3,PKNOX1,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,PSPC1,KDM5A,SCFD2,ASAP3,SCMH1,PDE2A,TMEM187,EIF5B,NAALADL2,CTIF,ZNF221,DAGLB,GADD45A,WDR35,AGTPBP1,NFKBIB,GNB3,ASCC1,CACNA1H,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,NEK6,SREBF2,PMAIP1,RASSF3,FAAH2,RABGAP1L,PDS5B,WIZ,HRG,FXN,AVEN,CDK6,PTPRM,GNL3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,SUPT4H1,FIP1L1,MEF2C,LPP,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,ABCA7,SLC39A11,SH2B3,DDX56,KIAA1671,SLC38A5,INTS7,MCM5,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,COQ3,FMNL2,SERBP1,HMGCR,PEA15,GTF2H3,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,MBNL2,EVI5,VPS13C,LRP1B,TASP1,CLASRP,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,DNM3,TRERF1,DDX18,ATP6V1A,PDK4,MYH9,TUBB6,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,FMNL1,CEP63,PERP,GARS,FAM111B,STAMBP,ARHGEF10,ADAM32,ATP6V0A1,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,LRCH1,TRIM36,XPC,SESTD1,ID2,WDR37,JMJD6,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,PVRL3,ARHGAP1,HNRNPM,SOX6,ULBP1,DIS3L2,DDHD1,FAM98A,C21orf58,FBXO17,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,IL6R,PDE3B,DDX49,FOXC1,RPA1,ETFDH,RARS,TRIB3,BAZ2B,PXDN,POLE2,ARID3B,SLCO5A1,PTPN4,PSAP,IGBP1,CORO2B,KDM4C,ANAPC4,BCAS4,POLR1A,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,UBAP2L,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,FLNC,CHD9,ABCC4,BAZ2A,KATNAL1,MED27,GMFB,COL4A3BP,NOL6,BRCA1,CCDC28B,PEX1,KIF16B,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,CHMP4C,XYLB,OXNAD1,AOC3,MCM6,PGPEP1,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,BARX2,RLF,DOPEY1,RNF40,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,SYNJ2,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,BCS1L,WDR25,MEX3B,ZNFX1,SUPT5H,VAC14,NR2F1,PWP1,NAP1L5,ATXN7,SPAG9,FAM135A,PALB2,SYNCRIP,DNAH17,PPP1R12B,ARHGAP12,HMBS,NAPA,PRKAR2A,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,RNF24,KDM1A,CAD,METTL16,UBR1,FSIP2,ARMC5,IKBKB,ETF1,RNF2,HIBCH,ZFP37,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SKIV2L,WDR36,PCGF3,NARS,GLTSCR2,THSD4,AKAP13,ENC1,NUP214,ARL5B,TMEM186,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,ZNF333,CLEC16A,ITGA2,TSSC1,PUS1,ZNF18,NFASC,SEPT5,ZNF589,ATXN7L2,UNC13D,MAP3K13,C14orf159,ZNF346,CSNK1A1,ZNF594,PTPN2,FAM50A,SACS,ANXA7,IFIT5,DDX31,CD44,PCK2,FBXO31,FAM71E1,ADAMTSL3,TPM4,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,HIST1H4J,GPNMB,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,ZRANB3,POLR3G,SRBD1,SET,MSH3,GLG1,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRKAB2,TNFRSF21,PLRG1,ADAMTS6,IKBIP,RAC3,UBR5,MGA,GIPR,PAK1IP1,ME1,CEP135,MEIS3,SEH1L,TBC1D8,DDN,SLC38A6,SETD1B,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,CUX1,TCEB3,SEMA3F,SAP30BP,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,GREB1L,DNAH2,CCNB1IP1,ZNF598,PTPN14,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,TGFBR2,CHD5,CD226,IGF2BP3,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ASAP1,COPS3,ATIC,SAMD13,IGF2BP1,PRPS1,TERF2,SCAF11,SIK3,DDX28,SIGMAR1,POLA1,AOC2,KIAA0586,TTYH2,PTPN12,PLCB1,ARIH2,DAGLA,EPRS,KIDINS220,PMEPA1,ZZEF1,ZBTB12,D2HGDH,RIOK3,UMPS,IQSEC2,MAP2K4,RTTN,TRPM2,ZBTB37,URB2,HFM1,OLA1,AP1B1,FOSL2,LTB4R,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,SHC1,KDM2A,UCHL5,PNPLA4,SERPINH1,KMT2A,PLEKHA4,RFC4,ZCCHC14,RFC3,MPP6,PDK1,MTIF2,DLG4,KIAA1586,GALK2,PNN,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,UTP14A,C10orf2,TCF3,ZNF280C,MON2,MLH1,IKBKAP,NOL3,GDPD5,FOXO3,TMCO6,NEDD4,MAD2L2,RGS17,PTRF,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,PLEKHG4,MBTPS2,FAM120B,TSHZ1,WDFY3,FZD3,TBRG4,NOP58,KLHL22,FBXO21,ZDHHC11,HELZ,RNF138,MYOM2,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,RCHY1,ZNF107,ANKRD18A,SIRT2,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,ANAPC1,RAP1A,THADA,LONRF2,ANAPC10,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,NDUFA6,OGG1,TRIM14,PRKACB,TRIP13,LONP1,ZBTB17,LAMA4,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,HDAC8,CAV1,SOX4,TCTN1,SERGEF,TAF9B,PAF1,RHOU,GEMIN5,TMEM132B,UBTF,EPN2,SUFU,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,AK2,PIGN,FN1,SEC24D,TAF1,PAX2,ALG8,MED13L,XPO7,RHBDD1,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,NRIP1,N4BP2,RANBP6,PDE4A,TSTA3,WWC1,PRDM1,ANKRD20A4,ATAD5,INTS5,SDCCAG8,EXOC4,HK2,C7orf26,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,GBF1,SLC39A1,ZSCAN5A,VPS18,BRE,CCDC50,CAMTA2,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,MOSPD1,TMLHE,MCEE,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,RAB10,TPK1,RAD54B,ZC3H12A,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,CLSTN2,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,TTC17,AMOT,DMRT1,IL11RA,TEAD1,ANKMY2,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,RERE,MFN2,MPP7,ZNF330,CUL2,ZRANB2,MBD6,TATDN1,PREPL,ZAK,MMP16,SLC16A10 |
| 4.212e-07 | -14.68 | AMUNDSON_RESPONSE_TO_ARSENITE | MSigDB lists | AMUNDSON_RESPONSE_TO_ARSENITE | 212 | 54 | 17758 | 2279 |
CARS,ZNF254,CLK1,LAMTOR3,PIK3R4,PLOD1,PRKCA,FOXO3,EIF2S2,ASNS,KDM2A,BCAS2,DNAJB6,TANK,STC2,PDS5B,RELB,GTF2H1,ME1,HIBCH,CHD2,GTF3C3,ZNF85,SERPINH1,ITGAX,CDK6,ATP6V0D1,TRIP13,CLK2,SRPK2,GARS,UPP1,AP4B1,TOP3A,ATP6V0A1,MARS,MED16,STK10,ST3GAL5,NEU1,WARS,PLIN2,ADNP,TIMM17A,ARNTL,RRAGA,ASB3,TBL1X,HMBS,POLR1C,RPS6KC1,DDIT3,N4BP2L2,SLC43A1 |
| 4.344e-07 | -14.65 | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 7783 | 1107 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,SBF2,CCNL2,HMOX2,SLC6A8,LPAR3,CIAPIN1,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,NRAS,KLHL23,LIMA1,EHMT1,AP4B1,KIF15,C11orf80,WDHD1,ABCC2,ZNF197,PYCR1,AHNAK,LRRC40,RUNX1,SLC25A26,ZNF532,TMEM63C,FAM189B,TRIO,PARN,PITPNM1,RSPRY1,RBM20,UBE3A,CNST,DHX37,MED24,WDR60,GEMIN4,MRPL21,PABPC1,SAMD3,ANGPT2,KLRD1,ZNF675,IFRD1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,USP10,MAP7D1,SRA1,IRS1,DYNC1H1,TSR1,NME7,EHMT2,TRAP1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,RAB11FIP4,C16orf45,FAM122B,ISG20L2,LCLAT1,ZMAT2,RPGRIP1L,ESAM,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,MSH4,ZC3H3,LYST,PMS1,KMT2D,SLCO6A1,PCNXL2,MEF2D,KCNH3,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,ARHGAP21,ELP2,KDM4B,ARL13B,POLR3E,RPS6KB1,CENPBD1,METTL2B,CEP170,MAPT,MORC2,XRRA1,ATG2B,POLR3D,TAF3,UNC13A,ACOT11,RAPGEFL1,ZNF710,FBXL19,ACTR3B,RPL22L1,SPTAN1,DDX24,CCDC150,ANXA1,NSD1,SRCAP,HERC1,ACOX1,AEN,BMP4,SORCS2,CUL7,SLC25A21,AMPD3,ECM1,NCKIPSD,ANKRD11,HKR1,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,ANK2,MARCKSL1,LAMA2,KCNH2,CRYBG3,BSN,TCF7L1,LSS,INSIG1,CHD3,C3orf35,PPP3CC,TSEN2,MAGI1,BEND6,CTU2,FOXO1,CLK1,ITFG1,PRSS3,MAPK8IP3,ARID1B,MLX,CEP290,VPS72,NDRG4,VAPB,CTR9,PNPLA3,CWF19L2,SNX29,USP49,SETD2,HAUS6,OBSCN,TBC1D2,PRPF40B,TTC38,CASS4,SIL1,PTP4A2,GGT7,DDX10,USP7,MPI,SART1,OLFM2,ARID2,RPS29,RIPK1,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PAG1,DDX60L,PLXNB1,ZNF608,ANKRD13A,NRF1,JAG1,NUP133,GRIN2C,ANKRD24,CCDC40,MYH15,BCAP29,IPO11,SOBP,ARHGAP17,AKAP8L,SSFA2,CA5B,TJAP1,EXO1,IFT81,LMBR1L,KLF4,INTS9,MED20,MUTYH,PARD3,ZNF507,DMGDH,RFX1,VARS,RBM19,HIST2H2AB,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,LRRIQ1,SMARCAD1,ABCF2,TOP3A,FERMT2,PALLD,SMPDL3B,POLR3A,DKK1,CDH24,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,RBM26,KIF1B,C6orf223,ZNF292,LUZP1,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,ZNF646,OSBP2,ZDHHC14,DENND4A,SON,DDX60,TMEM206,PLCXD2,GZF1,DOT1L,OSBPL1A,TRRAP,LSM14A,SH3RF1,LUC7L3,HSPBAP1,HIC2,XPNPEP1,NRP1,BMI1,NMD3,PRPF38B,LARS2,PRPF31,DLGAP4,NDUFS7,MTUS1,FAM192A,TECTA,SLC7A11,SCAF1,USPL1,MYC,PIGG,RTFDC1,FDFT1,RREB1,RAPGEF4,RAP1GAP2,ARID1A,EHBP1,ANGPTL4,MTR,SLC26A11,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,ZCCHC6,SQLE,DPEP1,NCOR1,HS2ST1,CPT1C,SYT17,BIRC6,TMEM104,PLEK2,POP5,PTPRG,IGSF1,BLOC1S2,NUBPL,DECR1,ARMC6,LPIN2,SOCS6,SHF,TTC3,CDK12,GON4L,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,ZBTB25,BAZ1A,MSX2,SMARCC1,WDR5B,MBTD1,FTSJ1,LARGE,IFT140,CBWD1,TRAF3,TBXA2R,SETD6,MID1,SSH2,NOSTRIN,BRAF,OPA1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,TTLL5,PXN,APEX1,ZFYVE1,BMS1,C9orf153,SLC23A2,RETSAT,ZNF155,DDX50,COQ9,ATM,SVIL,APAF1,IPO4,PIGM,ZNF76,LETM1,ATRX,RARS2,PCYOX1L,DST,MYH3,KIAA0922,HCFC2,YARS,DTNB,TNK2,DEAF1,SESN2,SKAP2,ZNF195,ARRDC3,TFPI,VWCE,MTHFD1L,SGK2,KMT2C,ST3GAL5,CCDC3,CC2D1B,CRCP,CSMD3,EME1,DCAF5,RHOBTB1,PCSK7,QSER1,EVPL,NAMPT,RNF141,ELL,PRF1,ZCCHC7,ATP6V0D1,AKAP11,HSD17B14,MTHFD1,ZNF234,PPAT,ELP3,ZBED4,JMJD1C,ZFP14,EIF2A,CORIN,AGAP1,EXOC6,MGAT2,SYCP2L,APBB3,BICD1,KIAA0355,FAT1,FDPS,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,DMXL2,TCF12,FEZ2,PSTPIP2,TMEM183A,SMARCA4,TBCCD1,COBLL1,SPATS2,DHX35,RIOK2,ZC3H13,RAET1E,PPFIBP1,SNTG2,ITGAX,C6orf89,MAML3,RTN4RL2,GRHL3,METTL2A,ATXN1,POU2F1,MRRF,EDEM2,UBR4,S100A16,ARMC4,ALAD,KPNA3,IKZF4,CEBPZ,TMEM101,NFRKB,BRD9,SMG1,TMEM33,TMCC1,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,WDR26,ATF7IP,MFHAS1,FAM49A,BMP6,SEC24C,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,KDM6B,SLC6A16,ZNF821,PSPC1,SCMH1,EIF5B,NAALADL2,WDR35,AGTPBP1,VPS37B,GNB3,CACNA1H,CSPP1,CHAC1,SYNJ1,AMBRA1,NOS1AP,TOM1L1,SREBF2,PDS5B,ZNF148,AVEN,GNL3,PTPRM,RFX2,AKAP12,PLEKHM3,C10orf76,RBM28,ZNF266,SUPT4H1,BRCA2,MEF2C,HERC2,CARS,EP400,CLDN15,KHDRBS1,NHS,RSF1,CLINT1,YARS2,ABCA7,DDX56,INTS7,MCM5,CACNB2,ANP32B,PRMT5,MAP3K12,COQ3,FMNL2,TOMM34,HMGCR,BDNF,TIMM8B,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,IMPDH2,EVI5,ABCF1,NCDN,VPS13C,LRP1B,GTF2A1,LEMD3,WDR33,ZNF516,DNM3,ABCA3,TRERF1,DDX18,ATP6V1A,MYH9,NECAP1,SAFB2,EEA1,ABCA12,FMNL1,ATRIP,GSTA4,CEP63,MTHFD2L,KRT7,ARHGEF10,ADAM32,FKBP3,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,CDC16,IQCH,PAM,WDR7,FUS,YEATS2,LAMA5,ANKS1A,LRCH1,ZNF786,XPC,TRAK1,SF3A3,JMJD6,TGFB2,RSRC1,POM121,KRI1,TMSB10,PVRL3,HNRNPM,SOX6,ULBP1,DIS3L2,ERICH1,ARHGAP39,MRPS10,PDE3B,RARS,TOE1,TRIB3,ETFDH,BAZ2B,PXDN,ARID3B,PTPN4,SLC25A19,PSAP,NUDT22,DOCK6,KDM4C,ANAPC4,CORO2B,POLR1A,TFIP11,PPARGC1B,CSNK2A1,RNF43,TMEM132A,SEC16A,ARHGAP18,DHX33,ETV1,CDC37,TMPO,FLNC,CHD9,GCNT2,SLC3A2,ABCC4,BAZ2A,KATNAL1,COL4A3BP,NOL6,BRCA1,ZNF91,MGST1,KIF16B,PEX1,GLS,ZNF622,TP53BP1,EEFSEC,CCDC146,TECPR2,TNFRSF1A,SGSM2,RNF214,XYLB,SEPHS2,OXNAD1,AOC3,MCM6,ITPRIP,TRIM15,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,TIMELESS,SYNJ2,ALDH18A1,CAMKK2,LAMC1,WDR25,ZNFX1,SUPT5H,TRAPPC6B,VAC14,NR2F1,PGD,PWP1,ATXN7,SPAG9,FAM135A,PALB2,SNAP23,DNAH17,PPP1R12B,ARHGAP12,PRKAR2A,GPR143,RSL1D1,RNF24,ZNF83,PELP1,CAD,UBR1,FSIP2,DNAJB6,ARMC5,C15orf40,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,SKIV2L,WDR36,EVL,THSD4,MANBAL,AKAP13,ENC1,NUP214,BTBD11,RANBP2,RBBP8,SIX5,CLEC16A,ITGA2,ZNF436,PUS1,NFASC,ZNF589,ATXN7L2,UNC13D,MAP3K13,MAP1S,C14orf159,BZW2,IQGAP2,FAM50A,SACS,ANXA7,ZNF561,PRICKLE2,DDX31,GREB1,PCK2,FBXO31,FAM71E1,GINS3,ADAMTSL3,DHX34,TEX14,PEAR1,GPNMB,RHOT2,TMEM175,PIK3CB,CHCHD6,ARMC3,NEU1,CENPP,POLR3G,C20orf196,SRBD1,MSH3,GLG1,ITGB4,MIPOL1,GCSH,MYCBP2,PRDX6,TNFRSF21,PLRG1,TMEM109,AARS,UBR5,MGA,PAK1IP1,RNF111,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DPF3,ATG9A,NR6A1,NOL8,EYA3,TCEB3,CUX1,MAK16,VPS13D,DNAH2,TXN2,FAM118A,SYNPO,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,ANKRD17,OPHN1,ANXA10,IGF2BP3,PRKCE,SLC16A9,IGF2BP1,LPCAT1,TERF2,USE1,SIK3,DDX28,SYNGAP1,AOC2,KIAA0586,TTYH2,ARIH2,DAGLA,EPRS,KIDINS220,SRRD,UBAP1,PMEPA1,ZZEF1,D2HGDH,PEX13,RTTN,TRPM2,CCDC58,SPATA2L,URB2,HFM1,C1QTNF7,KLHL18,AP1B1,PDE3A,PHC2,FLAD1,TERF2IP,CHD7,ZNF827,KDM2A,SHC1,VGF,SERPINH1,KMT2A,PLEKHA4,NAA35,RFC4,ZCCHC14,DLG4,KIAA1586,MED16,GALK2,PNN,STK10,DHX57,DCBLD2,VDR,ZNF236,TRMT2A,ANXA2,KLHDC4,MDN1,NOLC1,TROVE2,NCOR2,C10orf2,MRI1,TCF3,ZNF280C,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,NEDD4,ZNF483,RGS17,PTRF,LRP2BP,NISCH,PMPCA,RDX,UPF2,HARS2,PLEKHG4,FAM120B,TSHZ1,WDFY3,FZD3,YIF1A,KLHL22,ZDHHC11,HNRNPH3,MYOM2,PGAM5,BRWD3,SLC43A1,SLC37A3,PHF3,NF1,KIF5A,FANCD2,TRPM6,PLOD1,ZNF107,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,CUTC,EDC3,SMARCB1,ZNF804A,RTN1,ANAPC1,LONRF2,THADA,YLPM1,IPP,RELB,POLR3B,PCOLCE2,NDUFA6,CCDC121,LONP1,TIMM50,ZBTB17,LAMA4,ZNF680,GPCPD1,TCTN1,SERGEF,CHAF1A,CDHR3,PAF1,RHOU,TMEM132B,EPN2,SUFU,TRMT5,DNAJC1,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,VIPR1,RELL2,PIGN,AK2,FN1,TAF1,PAX2,DPF2,ALG8,MED13L,XPO7,PHGDH,CMTM3,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,NRIP1,N4BP2,KRT20,PDE4A,TSTA3,TBXAS1,WWC1,PRDM1,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,EXOC4,ZFP90,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,CELSR3,MYO7A,ST7L,GBF1,SLC39A1,ZSCAN5A,VPS18,CCDC50,CAMTA2,RPS6KL1,ZNF142,MET,ZNF460,HTRA2,MCEE,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,R3HDM1,ATP8B2,PUSL1,RAD54B,TPK1,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SCARB1,HEATR1,USP11,ECHDC1,YDJC,TNIK,SH2D3A,C17orf80,DBF4,NSUN6,LETMD1,PPHLN1,CLSTN2,CCDC7,MFSD10,SFI1,PRKCH,IL17RE,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,UTS2,SLC25A1,MSX1,ARHGAP32,LENG8,MEN1,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,ALG5,ZNF330,MBD6,ARHGAP27,HRH1 |
| 4.406e-07 | -14.64 | helicase activity | molecular function | GO:0004386 | 151 | 43 | 16491 | 2164 |
EP400,MCM6,DDX18,ATRX,C10orf2,HFM1,DDX19A,SMARCA4,HLTF,CHD5,DHX35,DDX60L,MCM9,CHD7,DDX56,DHX37,DHX33,MCM5,DDX31,CHD2,SKIV2L,DDX28,CHD9,DDX24,DDX41,SKIV2L2,SMARCAD1,EIF4A2,DHX34,MCM2,DDX60,DDX49,DHX57,RAD54B,ZRANB3,ANXA1,DDX3X,ASCC3,SRCAP,DDX50,HELZ,CHD3,DDX10 |
| 4.499e-07 | -14.61 | TCTCTCC,MIR-185 | MSigDB lists | TCTCTCC,MIR-185 | 119 | 36 | 17758 | 2279 |
TCF12,DCTN3,CADM4,HMGA2,LUZP1,PAX2,MED13L,PBX1,SMG7,LPCAT3,ST7L,SSBP2,KDM2A,ZNF3,SYNGAP1,FOXN3,ATAT1,ARID1A,BRCA1,MAT2A,WARS,BSN,CAMK2D,SLC30A3,IKZF4,SERF2,ASTN2,HIC2,KIAA1328,NFASC,ANXA2,MAGI1,SH3PXD2A,KIF1B,PRKAR2A,CORO2B |
| 4.587e-07 | -14.59 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 10324 | 1431 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MKS1,TUBE1,CCNL2,SLC6A8,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,AP1M1,MAD1L1,KDM5C,SRRM2,PPM1K,CCDC57,NRAS,EHMT1,AP4B1,NFIA,KIF15,C5AR1,WDHD1,ABCC2,MCM2,ZNF197,AHNAK,RAD18,LRRC40,SYNGR2,BDH2,DIRAS1,RIOK1,RUNX1,TPM1,ZNF532,BANP,TMEM63C,TRIO,PIK3R4,BTBD9,PDCD7,CDC73,PITPNM1,CHN1,UBE3A,DHX37,MED24,GEMIN4,MRPL21,PABPC1,SAMD3,MYB,GATAD2B,ZNF675,STAG1,ALG6,WDR61,KCNQ3,USP10,ST6GALNAC3,SNAP25,TRIM37,USP46,IRS1,DYNC1H1,KPNA1,GSTO2,RPL28,EHMT2,TRAP1,KIAA0196,ARHGAP10,SGSM3,SDSL,RAB11FIP4,MAB21L3,DDR2,CD99L2,FAM122B,ISG20L2,NUP43,ST3GAL6,LCLAT1,RPGRIP1L,ZBED2,CD96,ACD,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,SLCO6A1,MEF2D,KCNH3,SLC35D1,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,NSMCE2,CAMKMT,HOXA3,RPS6KB1,CENPBD1,METTL2B,CATSPERG,BAG1,MAPT,RAB30,HMGA2,XRRA1,ATG2B,GAS6,IP6K2,TAF3,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,FBXL19,C15orf41,SAMD4A,PNMA1,SPTAN1,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,LDHA,RSBN1,CCDC113,PPIP5K2,ANXA1,OXSR1,NSD1,SRCAP,HERC1,AEN,BMP4,MTMR1,CYP24A1,CUL7,RBM33,TRIM16,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,METTL8,TRIML2,ZMYM2,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,PPARG,CDK4,ANK2,HSPA5,TSN,SUMO3,LAMA2,KCNH2,DLST,CRYBG3,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,LSS,CHD3,ARL4A,E2F4,DPP4,ADAM9,PPP3CC,MAGI1,USP15,FOXO1,CLK1,ITFG1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ARID1B,SPIRE1,MBD2,VPS72,VAPB,CTR9,WNT16,LRSAM1,CWF19L2,USP49,SETD2,OBSCN,MAPK1IP1L,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,PTP4A2,DDX10,SH3PXD2A,USP7,SART1,ID1,ARID2,SLC48A1,NTSR1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,DDX60L,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,MYH15,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,VIM,CA5B,EIF3H,TJAP1,EXO1,LMBR1L,KLF4,MED20,MUTYH,PARD3,ZNF507,MCM10,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,ADH5,SURF2,TMEM161A,POLR1B,C12orf4,AP4S1,LRRIQ1,FOXN3,SMARCAD1,ABCF2,TOP3A,ARHGEF12,PALLD,SMPDL3B,POLR3A,DKK1,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,USP20,RBM26,RBPJ,NR2F2,XPO6,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,ZNF646,ACADS,FAM127A,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,PLCXD2,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,SH3RF1,CCNT1,HSPBAP1,LUC7L3,XPNPEP1,NRP1,TNFRSF10D,BMI1,SPOCK3,ZMAT3,NMD3,PRPF38B,C9orf78,JUP,PRPF31,ST6GAL1,DLGAP4,CENPB,PRPF39,SSR4,PDCD5,FAM192A,TECTA,HR,NOVA2,USPL1,MYC,FDFT1,RREB1,PRIM2,ANAPC13,PCCA,RAPGEF4,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,MTR,SLC26A11,PHF6,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,VMA21,BIRC6,KIAA0232,PLEK2,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NUBPL,DECR1,SLX4,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,TTC3,CDK12,SAP30,BRD4,PREX1,LRRC8A,GNL1,SATB2,MARCH6,ERC1,ZBTB25,BAZ1A,CAMK2D,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,SLC4A7,TRAF3,XRCC4,MID1,SSH2,NOSTRIN,BRAF,KIF5C,DNAJC22,OPA1,INPP1,GIGYF2,ABL1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,CLK2,TMC7,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,ADSL,PACS1,BMS1,KLF6,INF2,RETSAT,IREB2,ORC5,ATM,SVIL,APAF1,ADK,IPO4,DDIT3,IMMP2L,PIGM,ZNF76,ATRX,RARS2,SLC30A7,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CEP128,SRPK2,DTNB,TNK2,DEAF1,FBXW4,SESN2,SKAP2,SIRT6,ARRDC3,VWCE,MINA,KSR2,COTL1,PITPNB,MTHFD1L,SGK2,KMT2C,TIMM44,HLCS,CC2D1B,CTAGE5,CSMD3,ASB3,EME1,CLU,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,ZCCHC8,UBXN1,PCSK7,QSER1,RNF141,ELL,WDR27,PRF1,ZCCHC7,LRP3,AKAP11,MTHFD1,MSI2,ZNF234,HBG2,PPAT,XPO5,ELP3,JMJD1C,ZBED4,LIG4,CORIN,SYT1,AGAP1,UBE2E1,MGAT2,SYCP2L,BICD1,KIAA0355,FSCN1,FAT1,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,TCF12,DMXL2,SNX27,DLL4,PSTPIP2,TNXB,PIGH,SMARCA4,PBX1,TBCCD1,COBLL1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,SOCS1,PPFIBP1,FHIT,ADCK4,ITGAX,VCL,C6orf89,GNG5,MAML3,NARS2,RTN4RL2,PRAME,GRHL3,METTL2A,ATXN1,MRRF,DKC1,UBR4,ARMC4,KPNA3,IKZF4,DUS3L,HNRNPR,ZNF557,DUSP19,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,WDR26,IGF2BP2,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,MFHAS1,FAM49A,GFM2,STC2,LDLRAD3,ERI3,PKNOX1,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,PSPC1,KDM5A,SCFD2,ASAP3,SCMH1,PDE2A,TMEM187,EIF5B,NAALADL2,CTIF,ZNF221,DAGLB,GADD45A,WDR35,AGTPBP1,NFKBIB,GNB3,ASCC1,CACNA1H,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,NEK6,SREBF2,PMAIP1,RASSF3,FAAH2,RABGAP1L,PDS5B,WIZ,HRG,FXN,AVEN,CDK6,PTPRM,GNL3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,SUPT4H1,FIP1L1,MEF2C,LPP,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,ABCA7,SLC39A11,SH2B3,DDX56,KIAA1671,SLC38A5,INTS7,MCM5,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,COQ3,FMNL2,SERBP1,HMGCR,PEA15,GTF2H3,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,MBNL2,EVI5,VPS13C,LRP1B,TASP1,CLASRP,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,DNM3,TRERF1,DDX18,ATP6V1A,PDK4,MYH9,TUBB6,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,FMNL1,CEP63,PERP,GARS,FAM111B,STAMBP,ARHGEF10,ADAM32,ATP6V0A1,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,LRCH1,TRIM36,XPC,SESTD1,ID2,WDR37,JMJD6,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,PVRL3,ARHGAP1,HNRNPM,SOX6,ULBP1,DIS3L2,DDHD1,FAM98A,C21orf58,FBXO17,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,IL6R,PDE3B,DDX49,FOXC1,RPA1,ETFDH,RARS,TRIB3,BAZ2B,PXDN,POLE2,ARID3B,SLCO5A1,PTPN4,PSAP,IGBP1,CORO2B,KDM4C,ANAPC4,BCAS4,POLR1A,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,UBAP2L,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,FLNC,CHD9,ABCC4,BAZ2A,KATNAL1,MED27,GMFB,COL4A3BP,NOL6,BRCA1,CCDC28B,PEX1,KIF16B,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,CHMP4C,XYLB,OXNAD1,AOC3,MCM6,PGPEP1,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,BARX2,RLF,DOPEY1,RNF40,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,SYNJ2,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,BCS1L,WDR25,MEX3B,ZNFX1,SUPT5H,VAC14,NR2F1,PWP1,NAP1L5,ATXN7,SPAG9,FAM135A,PALB2,SYNCRIP,DNAH17,PPP1R12B,ARHGAP12,HMBS,NAPA,PRKAR2A,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,RNF24,KDM1A,CAD,METTL16,UBR1,FSIP2,ARMC5,IKBKB,ETF1,RNF2,HIBCH,ZFP37,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SKIV2L,WDR36,PCGF3,NARS,GLTSCR2,THSD4,AKAP13,ENC1,NUP214,ARL5B,TMEM186,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,ZNF333,CLEC16A,ITGA2,TSSC1,PUS1,ZNF18,NFASC,SEPT5,ZNF589,ATXN7L2,UNC13D,MAP3K13,C14orf159,ZNF346,CSNK1A1,ZNF594,PTPN2,FAM50A,SACS,ANXA7,IFIT5,DDX31,CD44,PCK2,FBXO31,FAM71E1,ADAMTSL3,TPM4,TEX14,DHX34,RAP1GDS1,PEAR1,C11orf49,HIST1H4J,GPNMB,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,ZRANB3,POLR3G,SRBD1,SET,MSH3,GLG1,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRKAB2,TNFRSF21,PLRG1,ADAMTS6,IKBIP,RAC3,UBR5,MGA,GIPR,PAK1IP1,ME1,CEP135,MEIS3,SEH1L,TBC1D8,DDN,SLC38A6,SETD1B,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,CUX1,TCEB3,SEMA3F,SAP30BP,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,GREB1L,DNAH2,CCNB1IP1,ZNF598,PTPN14,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,TGFBR2,CHD5,CD226,IGF2BP3,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ASAP1,COPS3,ATIC,SAMD13,IGF2BP1,PRPS1,TERF2,SCAF11,SIK3,DDX28,SIGMAR1,POLA1,AOC2,KIAA0586,TTYH2,PTPN12,PLCB1,ARIH2,DAGLA,EPRS,KIDINS220,PMEPA1,ZZEF1,ZBTB12,D2HGDH,RIOK3,UMPS,IQSEC2,MAP2K4,RTTN,TRPM2,ZBTB37,URB2,HFM1,OLA1,AP1B1,FOSL2,LTB4R,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,SHC1,KDM2A,UCHL5,PNPLA4,SERPINH1,KMT2A,PLEKHA4,RFC4,ZCCHC14,RFC3,MPP6,PDK1,MTIF2,DLG4,KIAA1586,GALK2,PNN,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,UTP14A,C10orf2,TCF3,ZNF280C,MON2,MLH1,IKBKAP,NOL3,GDPD5,FOXO3,TMCO6,NEDD4,MAD2L2,RGS17,PTRF,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,PLEKHG4,MBTPS2,FAM120B,TSHZ1,WDFY3,FZD3,TBRG4,NOP58,KLHL22,FBXO21,ZDHHC11,HELZ,RNF138,MYOM2,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,RCHY1,ZNF107,ANKRD18A,SIRT2,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,ANAPC1,RAP1A,THADA,LONRF2,ANAPC10,RELB,IPP,HYAL1,JOSD1,POLR3B,PCOLCE2,NDUFA6,OGG1,TRIM14,PRKACB,TRIP13,LONP1,ZBTB17,LAMA4,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,HDAC8,CAV1,SOX4,TCTN1,SERGEF,TAF9B,PAF1,RHOU,GEMIN5,TMEM132B,UBTF,EPN2,SUFU,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,AK2,PIGN,FN1,SEC24D,TAF1,PAX2,ALG8,MED13L,XPO7,RHBDD1,DDIT4,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,NRIP1,N4BP2,RANBP6,PDE4A,TSTA3,WWC1,PRDM1,ANKRD20A4,ATAD5,INTS5,SDCCAG8,EXOC4,HK2,C7orf26,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,GBF1,SLC39A1,ZSCAN5A,VPS18,BRE,CCDC50,CAMTA2,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,MOSPD1,TMLHE,MCEE,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,RAB10,TPK1,RAD54B,ZC3H12A,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,CLSTN2,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,TTC17,AMOT,DMRT1,IL11RA,TEAD1,ANKMY2,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,RERE,MFN2,MPP7,ZNF330,CUL2,ZRANB2,MBD6,TATDN1,PREPL,ZAK,MMP16,SLC16A10 |
| 4.605e-07 | -14.59 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 139 | 40 | 17758 | 2279 |
HERC2,ARHGAP26,SNX27,ANKRD17,MAPK8IP3,KIF5C,RTN4,ABHD6,FAM8A1,SPIRE1,RASSF3,VPS52,GLTP,FNIP2,CLDND1,RAN,ZNF710,AHCYL1,FMNL2,FADS1,SIK3,MYO10,STAMBP,AGPAT4,ZFP14,NOL6,TTYH2,PTK2,TRIM37,TJAP1,GZF1,FBXO21,ARHGAP21,EIF4ENIF1,KIDINS220,LARGE,DIRAS1,PREPL,RABEP1,KIF1B |
| 4.740e-07 | -14.56 | BLALOCK_ALZHEIMERS_DISEASE_DN | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_DN | 1209 | 213 | 17758 | 2279 |
THOC5,ATRX,TNFRSF21,RCHY1,CSNK2A1,HLTF,SYNJ1,ABHD6,MGA,NOS1AP,PCDH7,RTN1,EXOC1,SRSF2,COPS4,SYN2,PDS5B,ME1,SRPK2,DDN,DEAF1,GPM6A,FAM127A,ABCC4,SKAP2,RNMT,HSPA5,VSNL1,AKAP12,PSMG1,WDHD1,PITPNB,SON,DENND4A,SERGEF,PEX1,ARPC3,BSN,GLS,HPRT1,SUPT4H1,TRRAP,MPV17,ZMAT3,MEF2C,USP15,EFNB2,HERC2,FN1,CCDC53,KHDRBS1,ALG8,PRAF2,PIK3R4,LAMTOR3,XPO7,PDCD5,SLC1A1,CHN1,SUB1,ATIC,CACNB2,NDRG4,NRIP1,PRPS1,AKAP11,PPA1,SERBP1,NT5E,MTHFD1,RABEPK,NIPSNAP1,USE1,IFRD1,CAMKK2,WDR61,ANAPC13,IFNGR2,RB1CC1,PCCA,RAPGEF4,PSMA1,USP10,SNAP25,PLCB1,SYT1,TRIM37,ARIH2,RDH11,SEC31A,DYNC1H1,LRP1B,TASP1,KIDINS220,SYNCRIP,RRAGA,TBPL1,PTRH2,PFDN2,DHCR7,MAP2K4,DMXL2,ZNF706,NDUFA5,CHMP2A,PCNT,PAFAH1B1,NPAS2,ATP6V1A,ACTR3,NDUFB5,NECAP1,UBL5,STAM,NDUFB3,TERF2IP,RPP30,BRE,SPG21,BCAS2,PPID,ZNF142,GSTA4,BCAP29,TTC3,SSBP1,FHIT,MET,PEG10,MGLL,NAA35,HTRA2,CASP8AP2,PRPF19,COL5A2,NARS,STAMBP,RAB7A,PCMT1,R3HDM1,ATXN1,PNN,ENC1,FKBP3,SNCA,RANBP2,KPNA3,HNRNPR,COPS5,TIMM17A,PAM,WDR7,LARGE,ACP1,SLC25A11,EIF2B3,NOLC1,AP2S1,TRIM36,AUH,CA11,PDE4B,LETMD1,SLC25A12,KIF5C,FARS2,RTN4,VARS,BHLHE40,OPA1,REEP5,MAN1A1,ADH5,TTC1,PEX7,SACS,ANXA7,LTN1,SELT,RAPGEFL1,ACTR3B,HSD17B12,SNAPC5,TOP1,AP4S1,APEX1,PSAT1,CRIM1,TMEM126B,PSPC1,LDHA,SULT4A1,RAP1GDS1,MRPS10,FERMT2,MARS,YIPF3,PDE2A,ECH1,UBC,FBXO21,DSC2,STX1A,HERC1,CUL2,ORC5,EIF2S1,DNAJC12,NCBP2,PREPL,MTMR1,ADK,KIF1B |
| 4.782e-07 | -14.55 | REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | MSigDB lists | REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | 610 | 121 | 17758 | 2279 |
TCF12,ZNF254,ZNF76,ID1,TRERF1,UBN1,NPAS2,ATRX,RBFOX2,PPARGC1B,PBX1,BCOR,SIRT2,FOSL2,GABPB2,IGSF1,MAP2K3,SMARCB1,TERF2IP,NRF1,SREBF2,ZFHX3,PHF5A,JAZF1,IKBKB,ZEB1,ZNF148,CHD2,HCFC2,CARM1,MAML3,KAT8,ATF4,TFCP2,NR6A1,PPARG,MED27,TCEB3,CUX1,POU2F1,ATXN1,HDAC8,BRCA1,ERC1,UBTF,VDR,SMAD3,DYRK1B,RBBP8,SUPT4H1,SUFU,GATA6,SMARCC1,ELP2,CHD3,PER1,KLF4,MKL2,ARNTL,PQBP1,TNFRSF1A,RUNX1,MED20,HMGA2,EGR1,FOXO1,ZHX3,MAP3K13,KHDRBS1,TCF3,TRAK1,NFX1,ID2,ATF7IP,RSF1,TRIM22,IKBKAP,RPS6KA5,FOXO3,BMP6,TADA3,ABL1,SNW1,SUB1,PSMG4,ZNF354A,VPS72,MYC,BUD31,GTF2H1,TIMELESS,NRIP1,PABPC1,TERF2,CAMKK2,RREB1,KDM5B,FOXN3,SMARCAD1,KDM5A,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,MEN1,SUPT5H,TCF7L2,POLR3G,SRCAP,NSD1,MYBBP1A,KPNA1,HIF1A,SET,TBX3,RBPJ,NR2F2,DDIT3,KAT6A |
| 5.013e-07 | -14.51 | Chromatin modifying enzymes | REACTOME pathways | R-HSA-3247509 | 261 | 65 | 8202 | 1117 |
KMT2E,ARID2,SMARCA4,KDM1A,SMARCB1,KDM2A,KANSL1,KDM5C,KMT2A,CARM1,SAP30,KDM3B,KAT8,KMT2D,AEBP2,SETD1B,CDK4,EHMT1,HDAC8,SUPT20H,HIST1H2BL,SETD7,KMT2C,DOT1L,TRRAP,SMARCC1,KDM4B,ELP2,CHD3,H2AFX,YEATS2,NCOR2,EP400,AK6,ATF7IP,JMJD6,IKBKAP,HIST2H2AB,ARID1B,TADA3,SUV39H2,ELP5,VPS72,HIST2H3D,PRMT5,GATAD2B,KDM6B,KDM5B,KDM5A,PRDM16,ELP3,ARID5B,SETD2,SMARCD3,HIST1H4J,ARID1A,NSD1,ATXN7,EHMT2,TAF12,NCOR1,TBL1X,SMYD3,KDM4C,KAT6A |
| 5.013e-07 | -14.51 | Chromatin organization | REACTOME pathways | R-HSA-4839726 | 261 | 65 | 8202 | 1117 |
KMT2E,ARID2,SMARCA4,KDM1A,SMARCB1,KDM2A,KANSL1,KDM5C,KMT2A,CARM1,SAP30,KDM3B,KAT8,KMT2D,AEBP2,SETD1B,CDK4,EHMT1,HDAC8,SUPT20H,HIST1H2BL,SETD7,KMT2C,DOT1L,TRRAP,SMARCC1,KDM4B,ELP2,CHD3,H2AFX,YEATS2,NCOR2,EP400,AK6,ATF7IP,JMJD6,IKBKAP,HIST2H2AB,ARID1B,TADA3,SUV39H2,ELP5,VPS72,HIST2H3D,PRMT5,GATAD2B,KDM6B,KDM5B,KDM5A,PRDM16,ELP3,ARID5B,SETD2,SMARCD3,HIST1H4J,ARID1A,NSD1,ATXN7,EHMT2,TAF12,NCOR1,TBL1X,SMYD3,KDM4C,KAT6A |
| 5.331e-07 | -14.44 | HALLMARK_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 110 | 34 | 17758 | 2279 |
DNAJA4,CHAC1,PARN,DDIT4,NOP56,SRPRB,ASNS,SHC1,BANF1,STC2,EXOSC4,GEMIN4,ALDH18A1,CNOT4,ATP6V0D1,ZBTB17,EXOSC2,ATF4,PSAT1,SKIV2L2,HSPA5,EIF4A2,DKC1,SERP1,TARS,HERPUD1,SEC31A,YIF1A,MTHFD2,H2AFX,EIF2S1,CNOT6,DDX10,NOLC1 |
| 5.458e-07 | -14.42 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 192 | 50 | 17758 | 2279 |
CARS,CHMP2A,UBXN1,RSL1D1,VARS,APRT,PRKCA,TGFBR2,NDUFS7,RPP30,PRKCH,FARSA,NDUFV1,SREBF2,BANF1,NISCH,ANAPC10,MRPS27,ZNF142,SHMT2,PCK2,ATP6V0D1,SNAPC5,NIPSNAP1,ZNF629,SKIV2L,SKAP2,SETD1B,PCCA,TSN,PCMT1,MARS,IMPDH2,NEU1,CHAF1A,MFN2,ETFDH,TRRAP,AGTPBP1,CFD,GLG1,INTS9,TRAF3,MDN1,IQSEC2,DHCR7,AP2S1,RNF114,SLC43A1,KAT6A |
| 5.800e-07 | -14.36 | BENPORATH_ES_1 | MSigDB lists | BENPORATH_ES_1 | 362 | 80 | 17758 | 2279 |
DDX18,MFGE8,TMEM177,SLC29A1,SLC6A8,SEMA6A,NOP56,PRKD3,PMAIP1,DNAJB6,RABGAP1L,PAK1IP1,ETV1,PRMT3,TMPO,RFC4,RFC3,PDK1,ZNF195,SLC38A1,NPM3,GNL3,VSNL1,NLN,WDHD1,PNN,MCM2,ARL5B,NUDT15,MAK16,MGST1,FGFR1,MAT2A,RAD54B,CHAF1A,CXADR,TCF7L1,RBBP8,CEBPZ,FKBP5,MDN1,PUS1,NOLC1,ZNF589,MCM10,MCM6,FOXO1,ST6GAL1,FAM46B,KIF5C,ZIC2,IGF2BP2,TRIM22,MAD2L2,IGF2BP3,PTPN2,GART,HAS3,NOP16,MCM5,DSG2,TNPO3,NOC3L,PRPS1,SERBP1,MTHFD1,PRIM2,FGF2,ELOVL6,RAP1GAP2,MARS,SRA1,PIK3CB,POLR3G,EPRS,MTHFD2,POLE2,RNF138,SLC16A1,AEN |
| 5.866e-07 | -14.35 | regulation of macromolecule metabolic process | biological process | GO:0060255 | 5698 | 842 | 16441 | 2138 |
ASCC1,THOC5,CHAC1,HLTF,CCNL2,ZNF44,NUP160,LPAR3,NOS1AP,SKI,ZNF37A,TOM1L1,NEK6,SREBF2,ZFHX3,IKZF5,PMAIP1,NSRP1,MAD1L1,WIZ,ZNF148,FNIP2,KDM5C,HRG,ZNRD1,CDK6,HMBOX1,EIF4E3,NRAS,GNL3,EHMT1,NFIA,KRBOX4,RFX2,C5AR1,DCUN1D5,SLC50A1,ZNF197,STOML2,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,FIS1,DIRAS1,RUNX1,ZNF532,MEF2C,BANP,EPM2AIP1,TRIP6,SLK,KHDRBS1,SIRT7,RSF1,PARN,CDC73,ABCA7,RBM20,CNST,UBE3A,APLF,ZNF326,MED24,ANP32B,CCDC88C,PRMT5,ZNF518B,MAP3K12,PABPC1,SERBP1,MYB,HMGCR,PEA15,ZNF675,GATAD2B,FADS1,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,USP10,SMARCD3,ARRDC4,MBNL2,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,KPNA1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,SPRED2,MAP2K5,ZNF516,TRERF1,GTF2H2C,PAFAH1B1,NPAS2,DDR2,MYH9,NUP43,SAFB2,HSPA1A,ACD,ERI1,ZKSCAN1,WAC,MMP14,ZC3H3,PERP,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,TAF2,FBXL5,CDC16,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,AKT1S1,TRIM22,BHLHE40,RNASEH2B,TGFB2,ZNF691,PSMF1,MBNL1,POM121,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,SPTAN1,FGF9,USP42,NXN,IL6R,ZNF467,UBE2K,FOXC1,UBC,OXSR1,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,POLR1A,CSNK2A1,NLE1,BIRC2,HNRNPLL,MAP2K3,ABL2,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,CDC37,PTPRK,CHD9,RBCK1,ZNF124,GCNT2,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,ANK2,HSPA5,TSN,MED27,GMFB,SUMO3,BRCA1,ODC1,ZNF91,MLLT10,KIF16B,DYRK1B,ZNF622,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,SOCS4,TNFRSF1A,ADAM9,DLX2,BEND6,UQCC2,USP15,TTN,FOXO1,CLK1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,HES6,BARX2,ZFP36L1,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,NDRG4,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,WNT16,CAMKK2,PAXBP1,CRADD,USP49,TLE3,SETD2,UTP15,SUPT5H,NR2F1,TCF7L2,ATXN7,SPAG9,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,BRSK2,TESC,PRKAR2A,BCCIP,USP7,ID1,CYLD,UPK3B,ARID2,RBFOX2,PPP2R2A,RIPK1,ZNF83,SSBP2,ZNF709,PELP1,ZNF121,KDM1A,ZBTB21,NRF1,JAG1,NUP133,GRIN2C,DNAJB6,IKBKB,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,PRMT3,CASP10,CTC1,PRPF19,SEC24A,KAT8,KDM3B,PCGF3,DDX41,KIRREL2,RAB7A,C1QTNF1,VIM,AKAP13,ENC1,NUP214,ZNF251,PUM3,EIF3H,USP36,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,PUS1,ZNF18,MED20,EIF2B3,ZNF589,PKIB,PARD3,ZNF507,NIFK,ESCO1,MINK1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ANKRD54,ZNF594,PTPN2,ANXA7,ZNF561,TMEM161A,HIST2H3D,SELT,POLR1B,FBXO31,CD44,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,TEX14,DHX34,HIST1H4J,PIK3CB,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,MSH3,GLG1,BCAS3,EIF2S1,FNTB,USP20,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,CUL4A,PRKAB2,PRKCA,GABPB2,AARS,UBR5,LPIN1,MGA,ZFYVE28,RNF111,CHD2,MEIS3,SEH1L,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,TCEB3,CUX1,SUPT20H,DENND4A,SON,SAP30BP,SPOP,GZF1,DOT1L,SKIL,TRRAP,CCNT1,LSM14A,SH3RF1,ARL6IP5,ZNF81,HIC2,TNFRSF10D,NRP1,BMI1,RFXAP,SPOCK3,PTPN14,WDR75,IFT57,DROSHA,EGR1,JUP,LARS2,ZHX3,ANKRD17,OPHN1,CENPB,GTF2IRD1,PID1,PDCD5,TGFBR2,CHD5,IGF2BP3,FKBP1A,PRKCE,HR,ZNF586,ENTPD5,NOVA2,MYC,IGF2BP1,LPCAT1,CAV2,TERF2,ADARB1,EXOSC2,SYNGAP1,RREB1,POLA1,RAP1B,ARID1A,NELFA,PLCB1,ZNF850,ARIH2,PHF6,ZNF425,CAT,ASCC3,EPRS,KIDINS220,ALKBH3,NSF,HIF1A,PMEPA1,SPEN,MED15,ZBTB12,PURB,DPEP1,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,BIRC6,ZBTB37,FOSL2,RING1,IGSF1,PAIP2,BLOC1S2,TERF2IP,CHD7,ZNF827,SLX4,SHC1,KDM2A,PPID,UCHL5,LPIN2,SOCS6,DTNBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,MTIF2,DLG4,SATB2,MED16,PNN,SETD7,STK10,ERC1,SERP1,SNCA,ZBTB25,VDR,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,ALKBH1,TRAF3,ANXA2,SETD6,MID1,NOSTRIN,NCOR2,BRAF,TCF3,ZNF280C,NFX1,RCAN1,MYNN,MLH1,IKBKAP,NOL3,RPS6KA5,GIGYF2,PHLDA2,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,RDX,CELF1,EXOSC4,YBX3,LARP4B,ERRFI1,MAP3K14,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,PXN,APEX1,ZFYVE1,PTK2,KLF6,GUF1,POLR2A,ZFP62,KLHL22,ZNF155,IREB2,ATM,APAF1,BRWD3,DDIT3,KAT6A,STK4,ZNF76,EIF3C,UBN1,ATRX,NF1,KMT2E,PTPRA,RCHY1,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,ANAPC1,RAP1A,YLPM1,JAZF1,ANAPC11,ANAPC10,RELB,ZEB1,PCOLCE2,SLC35C2,HCFC2,OGG1,TRIP13,PRKACB,TRIM14,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,TNK2,TRIM13,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,TFPI,ARRDC3,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,YTHDF2,TAF9B,PAF1,UBTF,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZC3H8,ZNF397,NOCT,DMTF1,MTCH1,EMSY,TNRC6A,FN1,TAF1,PAX2,DPF2,UBXN1,MED13L,PHGDH,RHBDD1,NAMPT,DDIT4,TOX4,RNF141,ELL,P3H1,ZNF354A,ATXN2,BUD31,NRIP1,POLR1E,ZNF629,VOPP1,ZNF234,XPO5,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,HERPUD1,ISG15,UBE2E1,APBB3,MYBBP1A,PTRH2,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,CELSR3,CEMIP,TNXB,SMARCA4,PBX1,CSTA,PIBF1,ZSCAN5A,RRN3,MPHOSPH10,BRE,SOCS1,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,HTRA2,MOSPD1,MAML3,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,DKC1,EDEM2,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,DUSP19,SRFBP1,HEATR1,NFRKB,USP11,BRD9,DNAJC2,TNIK,SUPT6H,CAMK1,H2AFJ,PPHLN1,MED18,IGF2BP2,ATF7IP,PPP1R1C,BMP6,SFI1,PRKCH,HAS3,STC2,UTS2,LDLRAD3,DMRT1,PKNOX1,TOP1,RPS6KB2,KDM6B,ARNTL2,MSX1,KDM5B,FGF2,CRIM1,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,PDE2A,MEN1,EIF5B,ZNF407,SYMPK,RERE,CTIF,ZNF221,HSPA1B,ZNF708,GADD45A,CUL2,ZRANB2,NCBP2,POLR1C,NFKBIB,ZAK |
| 5.899e-07 | -14.34 | RNA splicing | biological process | GO:0008380 | 352 | 79 | 16441 | 2138 |
SART1,THOC5,RBFOX2,TFIP11,PLRG1,PPIL1,ZMAT2,DHX35,HNRNPA3,SCAF8,UBL5,SRSF2,MPHOSPH10,BCAS2,PHF5A,NSRP1,GPATCH1,CPSF3,SRRM2,LSM10,CDK12,SRPK2,PRPF19,SF3A1,SNU13,PTBP2,DDX41,SKIV2L2,SFSWAP,PNN,SON,RBM28,CLNS1A,GEMIN5,HNRNPR,LUC7L3,PQBP1,PRPF4,FUS,TSEN2,PPIL3,PRPF38B,SUPT6H,PRPF31,ZCCHC8,SF3A3,JMJD6,PRPF39,NOL3,PDCD7,MBNL1,RSRC1,RBM20,SNW1,CTNNBL1,SCAF1,CWC27,ZNF326,BUD31,CELF1,GEMIN4,PRMT5,PABPC1,HNRNPM,SCAF11,PPP1R9B,USP49,PSPC1,TRA2A,MBNL2,POLR2A,PRPF40B,SYNCRIP,CLASRP,ZBTB8OS,HNRNPH3,SPEN,ZRANB2,NCBP2 |
| 6.041e-07 | -14.32 | skin-malignant_melanoma | COSMIC cancer mutations | skin-malignant_melanoma | 16562 | 2175 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,DYNC1H1,IRS1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,IGF2BP2,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,UNC13D,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SRRD,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 6.203e-07 | -14.29 | DNA repair | biological process | GO:0006281 | 483 | 101 | 16441 | 2138 |
BCCIP,USP7,POLB,ASCC1,CUL4A,GTF2H2C,ATRX,FANCD2,RCHY1,HLTF,RPAIN,UBR5,MCM9,SMARCB1,BRE,SLX4,ZSWIM7,KDM2A,COPS4,UCHL5,XRCC2,ATRIP,RNF111,MSH4,OGG1,SPIDR,TRIP13,PRPF19,PMS1,RFC4,RFC3,SIRT6,PARP2,EYA3,SUMO3,BRCA1,POLG2,RAD54B,CHAF1A,EXO1,TRRAP,RBBP8,BRCA2,KDM4B,RAD18,TP53BP1,NSMCE1,NSMCE2,COPS5,RAD51B,H2AFX,ALKBH1,EME1,NFRKB,COPS6,BRCC3,XRCC4,MUTYH,SMG1,EMSY,HERC2,HMGA2,XPC,FAN1,MLH1,RMI1,MAD2L2,SFR1,CEP164,ABL1,APLF,COPS3,GTF2H1,TIMELESS,COPS7B,GTF2H3,APEX1,POLK,POLA1,SMARCAD1,SETD2,TOP3A,USP10,LIG4,APTX,HIST1H4J,MEN1,POLR2A,UBC,ISG15,ZRANB3,RPA1,ASCC3,PALB2,POLE2,ALKBH3,GADD45A,CDK9,MSH3,ATM,WDR33 |
| 6.402e-07 | -14.26 | SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM | MSigDB lists | SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM | 156 | 43 | 17758 | 2279 |
DNAJC2,SARS,AUH,DDX19A,ALG8,NOP16,TRIAP1,ETF1,SSBP1,ANP32B,POLE3,RAN,YARS,PRMT3,PRPS1,SERBP1,DEAF1,SLC3A2,GARS,ITPA,USP10,PSMG1,UBE2K,SERP1,TARS,PWP1,EPRS,HPRT1,FBXO21,MTHFD2,SMARCC1,ZNF330,CTAGE5,HK2,EIF2S1,ACP1,SLC16A1,NR2F2,NOLC1,ZBTB11,DDX10,BLMH,RNF114 |
| 6.748e-07 | -14.21 | TIEN_INTESTINE_PROBIOTICS_24HR_UP | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_UP | 539 | 109 | 17758 | 2279 |
USP7,NDUFA5,LYRM4,PAFAH1B1,UROD,TMEM109,TMEM177,POP5,SLC25A44,SAFB2,UBL5,CIAPIN1,DENR,NOP56,NDUFB3,IDI1,SRSF2,UBAP2L,ETF1,HIBCH,RAN,NDUFA6,TRIM14,TRIP13,SEH1L,TMPO,RFC3,FAM127A,MIOS,HARS,ATOX1,TSN,GMFB,PCMT1,PNN,COTL1,MCM2,NUDT15,FKBP3,CXADR,DDX3X,MSX2,LSS,HPRT1,HSDL2,ALAD,DCXR,LUC7L3,SYNGR2,USP11,TPM1,BRD9,BMI1,MTCH1,MORC2,MCM6,DROSHA,LARS2,C10orf2,DBF4,PIK3R4,ID2,OPA1,LYRM2,PDCD5,REEP5,SLC1A1,DCTPP1,TTC1,COMMD9,SUB1,MCAM,MCM5,TRIAP1,MED24,GEMIN4,CELF1,UTS2,LPCAT1,SAMD4A,HNRNPM,SLC25A1,NUDC,HMGCR,FAM98A,EXOSC2,TIMM8B,GINS3,WDR61,TBRG4,ADSL,PHACTR2,MAPK1IP1L,PLCB1,CYB5B,RPA1,RDH11,RARS,SYNCRIP,POLE2,NSF,HNRNPH3,CUL2,TBX3,FDPS,UMPS,TBL1X,NR2F2,DHCR7 |
| 6.981e-07 | -14.17 | chromosomal part | cellular component | GO:0044427 | 755 | 142 | 17570 | 2233 |
THOC5,ATRX,PLRG1,NAT10,CSNK2A1,SIRT2,NUP160,SMARCB1,KANSL1,XRCC2,MAD1L1,PDS5B,RAN,POLE3,SEH1L,TMPO,HMBOX1,SIRT6,BAZ2A,CDK4,SUMO3,WDHD1,HIST1H2BL,MCM2,CHAF1A,TRRAP,RAD18,HLCS,TP53BP1,NSMCE1,E2F4,RAD51B,EME1,CCNB1IP1,ZC3H8,DCTN3,EP400,MCM6,ANKRD17,DPF2,SIRT7,CENPB,CDC73,CHD5,TOX4,RNF40,ELL,APLF,MCM5,MBD2,BUD31,CTR9,TIMELESS,ICE2,NRIP1,TERF2,GATAD2B,WDR61,PRIM2,STAG1,POLA1,SMARCD3,ARID1A,PLCB1,TCF7L2,PHF6,EHMT2,PURB,NCOR1,TCF12,PAFAH1B1,SMARCA4,NUP43,TNKS1BP1,PELP1,KDM1A,RING1,PHC2,TERF2IP,SLX4,BCAS2,ACD,KDM2A,NUP133,UCHL5,RNF2,MSH4,CTC1,HTRA2,PRPF19,KAT8,RFC4,BRD4,RFC3,ENC1,SMAD3,SMARCC1,KLF4,NSMCE2,H2AFX,PUS1,NFRKB,HMGA2,MCM10,ESCO1,TCF3,H2AFJ,MLH1,CSNK1A1,HIST2H2AB,POGZ,NEDD4,SFR1,POLR3D,SNW1,SUV39H2,CFDP1,HIST2H3D,EXOSC4,TOP1,TRNP1,SMARCAD1,TEX14,SCMH1,RANGAP1,APTX,HIST1H4J,MEN1,FOXC1,CENPP,POLR3G,RPA1,ZRANB3,POLE2,ZNF330,ORC5,BCAS3,ATM,MBD6,KDM4C,IPO4,KAT6A |
| 7.315e-07 | -14.13 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4650 | 692 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,HLTF,SLC6A8,NUP160,SYNJ1,NOS1AP,SKI,PCDH7,MMP7,NEK6,PMAIP1,RASSF3,FAAH2,RABGAP1L,MAD1L1,PDS5B,KDM5C,FXN,AVEN,SRRM2,CDK6,PTPRM,KIF15,AKAP12,MCL1,ABCC2,MCM2,ZNF197,DDX3X,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,DHX37,SLC38A5,APLF,MCM5,CACNB2,ANP32B,GEMIN4,MAP3K12,MYB,HMGCR,PEA15,ZNF675,GTF2H3,STAG1,PRDM16,EIF4A2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,IRS1,LRP1B,KPNA1,TRAP1,SURF1,ZNF160,GPN1,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,MMP14,ATRIP,MSH4,TRMT12,DENND1A,PMS1,KMT2D,ARHGEF10,ADAM32,ATP6V0A1,MEF2D,FKBP3,FGFR1,PDE8B,PES1,TAF2,GNG2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,HIPK2,PAM,RPS6KB1,FUS,BRCC3,ANKS1A,LAMA5,BAG1,RAB30,TRIM36,LRCH1,HMGA2,XPC,SESTD1,ID2,GAS6,IP6K2,POM121,TADA3,SUV39H2,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,ARHGAP39,LDHA,IL6R,DDX49,FOXC1,ANXA1,KISS1R,RPA1,OXSR1,TRIB3,POLE2,HERC1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,WDR13,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,PHKA1,DHX33,XRCC2,NCKIPSD,RAN,POLE3,ZMYM2,ETV1,PTPRK,VPS13B,DSC3,FMNL3,CHD9,ANK2,CDK4,TSN,HSPA5,COL4A3BP,GMFB,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,EEFSEC,ARL4A,E2F4,PER1,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,NKD2,SMAD7,LAMTOR3,MEX3A,HSD17B10,MAPK8IP3,HES6,SPIRE1,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,CRADD,SETD2,OBSCN,MEX3B,NR2F1,VAC14,PGD,SPAG9,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,GGT7,DDX10,SH3PXD2A,PRKAR2A,USP7,SART1,ID1,CYLD,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,ZNF83,PPP1R9A,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,FGGY,IKBKB,ETF1,RNF2,CORO1A,AHCYL1,IPO11,CASP10,KDM3B,SKIV2L,WDR36,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,ESCO1,AUH,MAP3K13,APRT,FOXP1,CSNK1A1,PTPN2,ADH5,FAM50A,SACS,SURF2,DDX31,POLR1B,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,POLB,MYCBP2,CUL4A,PRKAB2,TNFRSF21,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,MGA,SUCLG2,CHD2,CEP135,FAM127A,SETD1B,GNG7,EYA3,ZDHHC14,DENND4A,PLCXD2,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,WDR75,IFT57,DROSHA,JUP,EGR1,ANKRD17,ST6GAL1,CENPB,OPHN1,SSR4,TGFBR2,PDCD5,CHD5,FKBP1A,PRKCE,TECTA,NAV1,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,PIGG,SAMD13,IGF2BP1,PRPS1,TERF2,SIK3,DDX28,PRIM2,ANAPC13,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,PHF6,ATP9B,CAT,HIF1A,PMEPA1,VCAN,SPEN,RIOK3,C7orf50,UMPS,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,RTTN,BIRC6,URB2,PTPRG,FLNB,RING1,IGSF1,PHC2,NUBPL,TERF2IP,SLX4,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,RFC3,BRD4,PDK1,PREX1,SATB2,POLG2,STK10,ERC1,DHX57,BAZ1A,CAMK2D,SMARCC1,G6PD,DNAJA3,FTSJ1,H2AFX,ALKBH1,TRAF3,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,NOL3,IKBKAP,DNAJC22,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,COPS7B,NLGN3,S100A14,CLK2,NAV3,PXN,APEX1,FZD3,ADSL,FBXO21,ORC5,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,LRRC41,PIGM,PHF3,NF1,ATRX,RARS2,PTPRA,FANCD2,TRPM6,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,ANAPC10,RELB,PCOLCE2,OGG1,TRIM14,PRKACB,SRPK2,TNK2,SESN2,TRIM13,FBXW4,TXLNG,SIRT6,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,SOX4,SERGEF,TAF9B,GEMIN5,RHOU,DNAJC1,PQBP1,CSMD3,ASB3,CLU,EME1,ZC3H8,COPS6,MTCH1,FBXO45,AK2,PIGN,RHOBTB1,TAF1,DPF2,PCSK7,MED13L,EVPL,XPO7,DDIT4,RNF141,ELL,N4BP2,AKAP11,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,CORIN,SYT1,UBE2E1,ATAD5,HK2,TBL1X,FNBP1L,TBCK,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,PBX1,DHX35,RIOK2,BRE,SOCS1,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,ITGAX,MET,GNG5,MOSPD1,TMLHE,PHLDB2,PARP2,METTL2A,ATXN1,DKC1,UBR4,RAB10,RAD54B,IKZF4,KPNA3,COPS5,DUSP19,FKBP5,SCARB1,RNF130,USP11,SMG1,TMCC1,DNAJC2,BCKDK,TNIK,DNAJA4,SH2D3A,DYM,CAMK1,DBF4,MED18,IGF2BP2,ATF7IP,CCDC7,PPP1R1C,FAM49A,MFHAS1,PIP4K2A,PRKCH,CTNNBL1,TANK,TMEM99,AMOT,RPS6KB2,TOP1,KDM6B,DNMBP,IL11RA,GPHN,FGF2,KDM5A,MARS,ARHGAP32,TMEM187,NAPEPLD,GADD45A,WDR35,CUL2,NFKBIB,ZAK,MMP16 |
| 7.315e-07 | -14.13 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4650 | 692 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,HLTF,SLC6A8,NUP160,SYNJ1,NOS1AP,SKI,PCDH7,MMP7,NEK6,PMAIP1,RASSF3,FAAH2,RABGAP1L,MAD1L1,PDS5B,KDM5C,FXN,AVEN,SRRM2,CDK6,PTPRM,KIF15,AKAP12,MCL1,ABCC2,MCM2,ZNF197,DDX3X,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,DHX37,SLC38A5,APLF,MCM5,CACNB2,ANP32B,GEMIN4,MAP3K12,MYB,HMGCR,PEA15,ZNF675,GTF2H3,STAG1,PRDM16,EIF4A2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,IRS1,LRP1B,KPNA1,TRAP1,SURF1,ZNF160,GPN1,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,MMP14,ATRIP,MSH4,TRMT12,DENND1A,PMS1,KMT2D,ARHGEF10,ADAM32,ATP6V0A1,MEF2D,FKBP3,FGFR1,PDE8B,PES1,TAF2,GNG2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,HIPK2,PAM,RPS6KB1,FUS,BRCC3,ANKS1A,LAMA5,BAG1,RAB30,TRIM36,LRCH1,HMGA2,XPC,SESTD1,ID2,GAS6,IP6K2,POM121,TADA3,SUV39H2,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,ARHGAP39,LDHA,IL6R,DDX49,FOXC1,ANXA1,KISS1R,RPA1,OXSR1,TRIB3,POLE2,HERC1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,WDR13,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,PHKA1,DHX33,XRCC2,NCKIPSD,RAN,POLE3,ZMYM2,ETV1,PTPRK,VPS13B,DSC3,FMNL3,CHD9,ANK2,CDK4,TSN,HSPA5,COL4A3BP,GMFB,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,EEFSEC,ARL4A,E2F4,PER1,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,NKD2,SMAD7,LAMTOR3,MEX3A,HSD17B10,MAPK8IP3,HES6,SPIRE1,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,CRADD,SETD2,OBSCN,MEX3B,NR2F1,VAC14,PGD,SPAG9,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,GGT7,DDX10,SH3PXD2A,PRKAR2A,USP7,SART1,ID1,CYLD,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,ZNF83,PPP1R9A,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,FGGY,IKBKB,ETF1,RNF2,CORO1A,AHCYL1,IPO11,CASP10,KDM3B,SKIV2L,WDR36,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,ESCO1,AUH,MAP3K13,APRT,FOXP1,CSNK1A1,PTPN2,ADH5,FAM50A,SACS,SURF2,DDX31,POLR1B,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,POLB,MYCBP2,CUL4A,PRKAB2,TNFRSF21,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,MGA,SUCLG2,CHD2,CEP135,FAM127A,SETD1B,GNG7,EYA3,ZDHHC14,DENND4A,PLCXD2,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,WDR75,IFT57,DROSHA,JUP,EGR1,ANKRD17,ST6GAL1,CENPB,OPHN1,SSR4,TGFBR2,PDCD5,CHD5,FKBP1A,PRKCE,TECTA,NAV1,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,PIGG,SAMD13,IGF2BP1,PRPS1,TERF2,SIK3,DDX28,PRIM2,ANAPC13,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,PHF6,ATP9B,CAT,HIF1A,PMEPA1,VCAN,SPEN,RIOK3,C7orf50,UMPS,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,RTTN,BIRC6,URB2,PTPRG,FLNB,RING1,IGSF1,PHC2,NUBPL,TERF2IP,SLX4,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,RFC3,BRD4,PDK1,PREX1,SATB2,POLG2,STK10,ERC1,DHX57,BAZ1A,CAMK2D,SMARCC1,G6PD,DNAJA3,FTSJ1,H2AFX,ALKBH1,TRAF3,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,NOL3,IKBKAP,DNAJC22,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,COPS7B,NLGN3,S100A14,CLK2,NAV3,PXN,APEX1,FZD3,ADSL,FBXO21,ORC5,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,LRRC41,PIGM,PHF3,NF1,ATRX,RARS2,PTPRA,FANCD2,TRPM6,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,ANAPC10,RELB,PCOLCE2,OGG1,TRIM14,PRKACB,SRPK2,TNK2,SESN2,TRIM13,FBXW4,TXLNG,SIRT6,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,SOX4,SERGEF,TAF9B,GEMIN5,RHOU,DNAJC1,PQBP1,CSMD3,ASB3,CLU,EME1,ZC3H8,COPS6,MTCH1,FBXO45,AK2,PIGN,RHOBTB1,TAF1,DPF2,PCSK7,MED13L,EVPL,XPO7,DDIT4,RNF141,ELL,N4BP2,AKAP11,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,CORIN,SYT1,UBE2E1,ATAD5,HK2,TBL1X,FNBP1L,TBCK,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,PBX1,DHX35,RIOK2,BRE,SOCS1,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,ITGAX,MET,GNG5,MOSPD1,TMLHE,PHLDB2,PARP2,METTL2A,ATXN1,DKC1,UBR4,RAB10,RAD54B,IKZF4,KPNA3,COPS5,DUSP19,FKBP5,SCARB1,RNF130,USP11,SMG1,TMCC1,DNAJC2,BCKDK,TNIK,DNAJA4,SH2D3A,DYM,CAMK1,DBF4,MED18,IGF2BP2,ATF7IP,CCDC7,PPP1R1C,FAM49A,MFHAS1,PIP4K2A,PRKCH,CTNNBL1,TANK,TMEM99,AMOT,RPS6KB2,TOP1,KDM6B,DNMBP,IL11RA,GPHN,FGF2,KDM5A,MARS,ARHGAP32,TMEM187,NAPEPLD,GADD45A,WDR35,CUL2,NFKBIB,ZAK,MMP16 |
| 7.367e-07 | -14.12 | Regulation of cholesterol biosynthesis by SREBP (SREBF) | REACTOME pathways | R-HSA-1655829 | 54 | 22 | 8202 | 1117 |
SEC24A,CHD9,INSIG2,MVK,SEC24D,ELOVL6,SMARCD3,LSS,IDI1,INSIG1,SREBF2,SEC24C,FDPS,SQLE,TBL1X,RAN,GPAM,DHCR7,CARM1,MBTPS2,HMGCR,FDFT1 |
| 7.690e-07 | -14.08 | REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 283 | 66 | 17758 | 2279 |
ZNF254,TCF12,ZNF76,UBN1,NPAS2,PPARGC1B,PBX1,FOSL2,GABPB2,SMARCB1,NRF1,SREBF2,JAZF1,ZEB1,ZNF148,CHD2,HCFC2,MAML3,ATF4,PPARG,NR6A1,TFCP2,MED27,TCEB3,CUX1,HDAC8,BRCA1,SMAD3,SUPT4H1,RBBP8,SMARCC1,ELP2,CHD3,ARNTL,MKL2,TNFRSF1A,MED20,RUNX1,FOXO1,TRAK1,NFX1,ATF7IP,IKBKAP,BMP6,FOXO3,ABL1,TADA3,SUB1,SNW1,ZNF354A,MYC,VPS72,BUD31,GTF2H1,NRIP1,ELP3,SMARCD3,PRDM1,MEN1,SUPT5H,TCF7L2,NSD1,SRCAP,HIF1A,TBX3,NR2F2 |
| 7.772e-07 | -14.07 | OBSL1 (obscurin-like 1) | protein interactions | 23363 | 612 | 130 | 16036 | 2270 |
CGN,CUL7,NAT10,PLOD1,CSNK2A1,NLE1,NUP160,MGA,DST,SRSF2,YLPM1,ATG3,UBAP2L,PDS5B,RAN,SRRM2,FTSJ3,TIMM50,SF3A1,TMPO,FLNC,LIMA1,SKIV2L2,GNL3,HSPA5,NOL6,MCM2,SON,RBM28,STOML2,ARPC3,UBTF,DDX3X,TRRAP,AHNAK,LUC7L3,PQBP1,PRPF4,FIP1L1,WDR75,EP400,MCM6,JUP,PRPF31,KHDRBS1,HSD17B10,PHGDH,IGF2BP3,DDX56,SCAF1,MCM5,ZNF326,IGF2BP1,PABPC1,NIPSNAP1,CAMKK2,TRA2A,SUPT5H,ABCF1,DYNC1H1,MYBBP1A,SYNCRIP,TRAP1,SPEN,DDX10,TBKBP1,SART1,PCNT,DDX18,URB2,ACTR3,SMARCA4,RSL1D1,SAFB2,HNRNPA3,PELP1,URB1,FLNB,KDM1A,NOP56,CAD,BCAS2,NUP133,SERPINH1,UTP4,PRPF19,WDR36,DDX41,PCMT1,PNN,DKC1,NUP214,DSP,PUM3,PES1,RANBP2,HNRNPR,CEBPZ,MDN1,ANXA2,HEATR1,FUS,PDCD11,NOLC1,HMGA2,NIFK,SUPT6H,UTP14A,SF3A3,POM121,SNW1,SEC24C,DSG2,HIST2H3D,SHMT2,FBL,TOP1,PSPC1,WDR18,LDHA,RANGAP1,HIST1H4J,EIF5B,NOP58,UBC,POLR2A,ANXA1,SRCAP,DDX50,HNRNPH3 |
| 7.855e-07 | -14.06 | CHEN_HOXA5_TARGETS_9HR_UP | MSigDB lists | CHEN_HOXA5_TARGETS_9HR_UP | 205 | 52 | 17758 | 2279 |
CARS,DNAJC2,PRPF38B,FEM1C,EGR1,ZCCHC8,CLK1,NSUN6,ZNF107,RCHY1,RCAN1,CHAC1,IP6K2,FOSL2,ZNF44,RLF,PIBF1,FOXO3,BIRC2,PTPN2,ASNS,PMAIP1,TANK,STC2,WAC,RELB,RNF111,NOC3L,MTHFD2L,ZNF3,CNOT4,SEC24A,CHD9,IFRD1,PTBP2,ZNF195,PSPC1,JMJD1C,LIG4,MCL1,KLF6,TAF2,ZNF155,ADNP,ZNF557,AGTPBP1,TBX3,ARNTL,ZCCHC6,DLX2,DMTF1,HRH1 |
| 7.997e-07 | -14.04 | purine nucleotide binding | molecular function | GO:0017076 | 1837 | 309 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,RAPGEF4,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,PDK4,ACTR3,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,FAM114A2,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,PDE10A,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,PDE4A,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,HK2,RRAGA,SIL1,BRSK2,TBCK,DDX10,PRKAR2A,SUCLG1,PAPD4,MYO7A,SMARCA4,RIPK1,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,RAD54B,TPK1,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,PDE4B,TKFC,ARFIP2,VARS,APRT,CSNK1A1,PIP4K2A,MFHAS1,GFM2,PRKCH,GART,DDX31,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,DHX34,TEX14,MARS,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 8.182e-07 | -14.02 | REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT | MSigDB lists | REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT | 455 | 95 | 17758 | 2279 |
TCF12,ZNF254,ZNF76,TRERF1,UBN1,NPAS2,ATRX,PPARGC1B,PBX1,BCOR,FOSL2,GABPB2,MAP2K3,SMARCB1,NRF1,SREBF2,ZFHX3,PHF5A,JAZF1,ZEB1,ZNF148,CHD2,HCFC2,CARM1,MAML3,ATF4,TFCP2,NR6A1,PPARG,MED27,TCEB3,CUX1,HDAC8,BRCA1,UBTF,SMAD3,DYRK1B,RBBP8,SUPT4H1,SUFU,GATA6,SMARCC1,ELP2,CHD3,KLF4,MKL2,ARNTL,PQBP1,TNFRSF1A,RUNX1,MED20,HMGA2,FOXO1,ZHX3,TCF3,TRAK1,NFX1,ATF7IP,TRIM22,RSF1,IKBKAP,RPS6KA5,FOXO3,BMP6,ABL1,TADA3,SNW1,SUB1,ZNF354A,VPS72,MYC,BUD31,GTF2H1,NRIP1,RREB1,KDM5B,FOXN3,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,MEN1,SUPT5H,TCF7L2,POLR3G,SRCAP,NSD1,MYBBP1A,HIF1A,TBX3,RBPJ,NR2F2,DDIT3 |
| 8.252e-07 | -14.01 | transcription factor activity, protein binding | molecular function | GO:0000988 | 585 | 118 | 16491 | 2164 |
TRERF1,KMT2E,RBFOX2,PPARGC1B,SMARCA4,BCOR,BIRC2,LPIN1,KDM1A,SKI,SMARCB1,SRSF2,JAZF1,LPIN2,RELB,ZEB1,ZNF85,RAN,HCFC2,TRIP13,CASP8AP2,CARM1,SAP30,MAML3,AEBP2,ATF4,SIRT6,PPARG,MED27,MINA,MED16,SUPT20H,BRCA1,SOX4,TAF9B,BATF3,TAF2,DYRK1B,SMAD3,SKIL,MSX2,RBBP8,TRRAP,SMARCC1,ELP2,SUFU,TP53BP1,PER1,KLF4,COPS5,HIPK2,MKL2,PQBP1,PUS1,FUS,MED20,BEND6,RFXAP,PTPN14,HMGA2,WDR75,NCOR2,FOXO1,JUP,TAF1,ZHX3,TCF3,HES6,MED13L,MED18,ATF7IP,TRIM22,BHLHE40,ARID1B,SFR1,TADA3,SNW1,SUB1,HR,BUD31,MED24,YBX3,ZNF710,PRMT5,NRIP1,KDM5B,APEX1,FGF2,PRDM16,KDM5A,ARID5B,PSMC3IP,SMARCD3,WWC1,ARID1A,SRA1,NR2F1,RERE,ZNF783,TRIB3,NSD1,SRCAP,MYBBP1A,GTF2A1,PDLIM1,HIF1A,SPEN,MED15,TAF4,TBPL1,TAF12,NCOR1,TBL1X,NFKBIB,NR2F2,DDIT3,N4BP2L2,KAT6A |
| 8.278e-07 | -14.00 | regulation of nucleobase-containing compound metabolic process | biological process | GO:0019219 | 3908 | 598 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,TOM1L1,SREBF2,ZFHX3,IKZF5,NSRP1,WIZ,ZNF148,FNIP2,KDM5C,HMBOX1,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,ZNF197,STOML2,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,RUNX1,ZNF532,P2RY11,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,RBM20,APLF,ZNF326,MED24,PRMT5,ZNF518B,PABPC1,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,MBNL2,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,TASP1,KPNA1,GTF2A1,PDLIM1,EHMT2,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,KMT2D,ZNF480,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,FUS,BRCC3,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,MBNL1,TADA3,SNW1,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,HNRNPLL,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SLC25A23,TMPO,PTPRK,CHD9,RBCK1,ZNF124,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,E2F4,TNFRSF1A,DLX2,BEND6,UQCC2,USP15,FOXO1,CLK1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,TBPL1,ZNF430,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ZFP37,RNF2,AHCYL1,SPIDR,PRMT3,CTC1,PRPF19,KAT8,KDM3B,PCGF3,DDX41,ZNF251,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,ZNF589,PKIB,ZNF507,ESCO1,MAP3K13,RFX1,AGO2,FOXP1,HIST2H2AB,ZNF594,ZNF561,TMEM161A,HIST2H3D,SNAPC5,TRNP1,ZNF654,SMARCAD1,FOXN3,ZMYM5,DHX34,HIST1H4J,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,MSH3,BCAS3,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,CUL4A,PRKCA,GABPB2,UBR5,MGA,LPIN1,GIPR,RNF111,CHD2,ME1,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,SON,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,DROSHA,ZHX3,ANKRD17,CENPB,PID1,GTF2IRD1,CHD5,HR,ENTPD5,ZNF586,NOVA2,MYC,TERF2,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,ZBTB37,FOSL2,RING1,IGSF1,BLOC1S2,TERF2IP,CHD7,ZNF827,SLX4,KDM2A,SHC1,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,SATB2,MED16,PNN,SETD7,ERC1,ZBTB25,SNCA,BAZ1A,VDR,DNTTIP1,MSX2,CAMK2D,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,MLH1,IKBKAP,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,CELF1,YBX3,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,POLR2A,ZFP62,ZNF155,APAF1,BRWD3,DDIT3,KAT6A,ZNF76,KMT2E,NF1,ATRX,UBN1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,GPR87,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,SRPK2,ZBTB17,DEAF1,TRIM13,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,SUFU,GATA6,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,PAX2,DPF2,MED13L,DDIT4,NAMPT,TOX4,RNF141,ELL,ZNF354A,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,WBSCR22,ZFP14,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,PBX1,SMARCA4,ZSCAN5A,RRN3,BRE,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,HEATR1,NFRKB,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,KDM5B,FGF2,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NCBP2,NFKBIB,HRH1 |
| 8.398e-07 | -13.99 | UBC (ubiquitin C) | protein interactions | 7316 | 830 | 167 | 16036 | 2270 |
ADAM19,MYCBP2,CUL7,CUL4A,DPH1,FANCD2,RCHY1,CSNK2A1,SBF2,HLTF,TMEM132A,UBR5,BIRC2,PABPC4,AMBRA1,TOM1L1,ANAPC1,COPS4,ANAPC11,MAD1L1,JOSD1,ZNF148,TIMM50,RBCK1,PPARG,LIMA1,HSPA5,SUMO3,SEMA3F,BRCA1,DLST,STOML2,EPN2,RAD18,TOM1L2,CHD3,NSMCE1,XPNPEP1,PRPF4,CLU,COPS6,DCAF5,PTPN14,TNRC6A,USP15,HERC2,FN1,UBXN1,DLGAP4,FAN1,GTF2IRD1,PHGDH,IGF2BP3,CEP164,ELL,UBE3A,VAPB,GTF2H1,ATP6V0D1,MTHFD1,HMGCR,EXOSC2,TSTA3,RB1CC1,XPO5,TBXAS1,KIAA0586,PSMA1,USP10,MTR,HERPUD1,NCDN,ARIH2,IRS1,SYNCRIP,RPL28,UBAP1,HIF1A,TRAP1,FAT1,RIOK3,GPN1,DHCR7,AGO3,RNF114,RTTN,USP7,CYLD,BIRC6,LIN28B,DDX18,SPRYD7,RIPK1,NUP43,POP5,UBTD2,STAM,HNRNPA3,NOP56,FARSA,ANKRD13A,SLX4,BRE,BCAS2,CCDC50,NUP133,UBR1,UCHL5,DNAJB6,RNF2,TTC3,AUP1,PRPF19,PMS1,PRAME,RFC3,TUBA1A,NARS,STAMBP,PCMT1,MARCH6,TTC28,UBR4,EIF3H,SNCA,ZC3H12A,ZFAND3,HNRNPR,DNAJA3,COPS5,H2AFX,FUS,MDN1,RNF130,BRCC3,USP11,ANKS1A,MID1,MAPT,TRIM36,DNAJA4,XPC,AGO2,WDR26,MLH1,NEDD4,ABL1,LTN1,MAP3K14,FBL,AMOT,HSD17B12,HNRNPM,CEP83,PSAT1,LSM12,METTL23,ADSL,UBE2K,CHCHD6,UBC,RPA1,RARS,CUL2,POLR1C,RABEP1,DOCK6 |
| 8.531e-07 | -13.97 | mitochondrial part | cellular component | GO:0044429 | 915 | 166 | 17570 | 2233 |
IMMP2L,CYP24A1,LETM1,LYRM4,RARS2,MRPL10,SLC25A21,PRKCA,COA1,COX10,LPIN1,CIAPIN1,AMBRA1,MRPS30,PMAIP1,ATP5G2,LETM2,SUCLG2,NDUFA6,FXN,SLC25A23,PPM1K,LONP1,MPST,TIMM50,ACADS,GDAP1,MCL1,MTHFD1L,FOXRED1,DLST,FLVCR1,MPC1,MGST1,STOML2,TIMM44,PYCR1,DDX3X,GLS,TRMT5,MPV17,FIS1,CLU,TXN2,UQCC2,SLC25A26,MTCH1,HERC2,AK2,LARS2,HSD17B10,TIMM10,NDUFS7,YARS2,ETFB,PI4KB,ALDH18A1,MRPL21,COQ3,TOMM34,NIPSNAP1,TIMM8B,DDX28,BDNF,WARS2,PCCA,IDH3G,BCS1L,CPT1A,CYB5B,C19orf70,LYRM7,CAT,TRAP1,D2HGDH,SURF1,HK2,PDSS2,CPT1C,NDUFA5,SUCLG1,NDUFAF2,PDK4,NDUFB5,SLC9B2,SLC25A44,FDX1,MIEF1,NDUFB3,FLAD1,DECR1,ABCA12,SHC1,CBR4,MRPS27,RMDN3,HIBCH,SSBP1,ADCK4,MTHFD2L,TMEM14C,HTRA2,TMLHE,MCEE,NARS2,ACSL5,GARS,PDK1,SFXN4,CPOX,MRRF,NLN,CA5B,POLG2,SNCA,ATP5D,TAMM41,PEMT,DNAJA3,TIMM17A,SLC25A11,RPS6KB1,FAHD1,DMGDH,BCKDK,AUH,C10orf2,FARS2,SLC25A12,LETMD1,CHCHD10,OPA1,GFM2,SLC25A20,MRPS11,NDUFV1,TRIAP1,PMPCA,PHYKPL,SHMT2,HARS2,PCK2,NT5M,SLC25A1,TMEM126B,TMEM126A,ABCF2,MRPS10,EXOG,PDE2A,RHOT2,GUF1,CHCHD6,MMAA,MFN2,MRPL36,ANXA1,ETFDH,COQ9,SLC25A19,NDUFAF5,NDUFS5,GPAM,PGAM5,UQCC1,GCSH |
| 8.535e-07 | -13.97 | GCM_MYST2 | MSigDB lists | GCM_MYST2 | 168 | 45 | 17758 | 2279 |
EPM2AIP1,ANKRD17,RBFOX2,HECTD3,QSER1,IKBKAP,FOXO3,FAM8A1,POGZ,COMMD9,UBE3A,GATC,NUP133,RABGAP1L,SETD5,DCTN4,CELF1,ZMYM2,PKNOX1,KDM3B,CHD9,TRIM13,PTBP2,IDH3G,ZFP14,ARID1A,MARCH6,TRAPPC6B,ARL5B,UBE2K,ZNF655,ZFAND3,EIF4ENIF1,SPAG9,KIDINS220,TMEM237,KPNA3,SYNCRIP,ADNP,HNRNPR,HNRNPH3,LUC7L3,LEMD3,DMTF1,CEP170 |
| 8.736e-07 | -13.95 | ESR1 (estrogen receptor 1) | protein interactions | 2099 | 683 | 142 | 16036 | 2270 |
ASCC1,THOC5,PRKCSH,PPARGC1B,NAT10,RAC3,SKI,SRSF2,RPS16,UBAP2L,RAN,YARS,SRRM2,FTSJ3,SRPK2,ZBTB17,DBN1,CHD9,RBCK1,PPARG,GNL3,MED27,CAV1,BRCA1,RBM28,GNAI1,SPOP,YTHDF2,UBTF,SKIL,DDX3X,TRRAP,AHNAK,CCNT1,LUC7L3,PQBP1,VPS13D,DNAH2,EP400,CELSR1,JUP,FOXO1,KHDRBS1,RNF40,UBE3A,EIF2S2,CEP290,MBD2,MYC,MED24,GTF2H1,ANP32B,NRIP1,PABPC1,SERBP1,MTHFD1,BDNF,ZNF512B,SMARCD3,ARID1A,SRA1,NR2F1,POP1,IRS1,EPRS,MYBBP1A,SYNCRIP,RPL28,PDLIM1,EHMT2,NSF,HIF1A,NCOR1,SMYD3,DDX18,RBFOX2,ACTR3,SMARCA4,RSL1D1,MYH9,AP1B1,SAFB2,HNRNPA3,PELP1,FLNB,KDM1A,NOP56,FARSA,DECR1,SHC1,BCAS2,PPID,GLYR1,SERPINH1,PRPF19,WDR36,KMT2D,TUBA1A,POU2F1,MED16,AKAP13,SETD7,DKC1,TAF2,SMAD3,KDM4B,HNRNPR,COPS5,H2AFX,FKBP5,ANXA2,MED20,FUS,BAG1,NCOR2,SUPT6H,FOXO3,SFI1,SLC25A20,TADA3,SHMT2,RDX,POLR1B,YBX3,HNRNPM,SPTAN1,TOP1,PSPC1,KDM5A,WDR18,MARS,MEN1,NOP58,POLR2A,NSD1,DDX50,GADD45A,SET,BCAS3,SVIL,PGAM5,KAT6A |
| 8.783e-07 | -13.95 | WEST_ADRENOCORTICAL_TUMOR_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_UP | 284 | 66 | 17758 | 2279 |
MVK,SMARCA4,UBL5,LPIN1,PCYOX1L,SRPRB,CAD,JAG1,PMAIP1,GRIN2C,DNAJB6,MAD1L1,POLE3,KIAA0922,NAA35,GNG5,TMPO,NRAS,TFCP2,NOL8,MED27,SLC35D1,MCM2,FGFR1,CHAF1A,ARPC3,LSS,YIPF2,KDM4B,KPNA3,PDE4B,RTN4,CLINT1,BZW2,IGF2BP3,EIF2S2,MCAM,PI4KB,SLC7A11,INTS7,TNPO3,ANGPT2,HMGCR,PCSK6,FDFT1,ELOVL6,ANKMY2,MARS,UBE2K,NEU1,RDH11,DYNC1H1,EPRS,TPD52L2,RARS,MTHFD2,GADD45A,FDPS,SNX24,RIOK3,SQLE,SLC16A1,PTP4A2,DHCR7,KIF1B,XPO6 |
| 8.900e-07 | -13.93 | KMT2A (lysine (K)-specific methyltransferase 2A) | protein interactions | 4297 | 81 | 29 | 16036 | 2270 |
KAT8,WDR61,SIRT7,MEN1,SYMPK,CDC73,PLXNB1,POLR2A,SMARCB1,DOT1L,PAF1,ELL,SNW1,TASP1,CCNT1,CDK9,E2F4,SET,SVIL,CTR9,SENP3,RNF2,RUNX1,KMT2A,HCFC2,BMI1,TOP1,KAT6A,MYB |
| 8.905e-07 | -13.93 | haematopoietic_and_lymphoid_tissue | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue | 15119 | 2012 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,RAD18,LRRC40,SYNGR2,BDH2,MPV17,RIOK1,RUNX1,TPM1,VASH2,ZNF532,SLC25A26,P2RY11,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,CCDC85B,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,RAB11FIP4,GTF2H2C,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,UBL5,MCM9,RPGRIP1L,NDUFB3,CD96,ESAM,SPG21,ZSWIM7,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,METTL2B,CEP170,CATSPERG,BAG1,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,RPL22L1,SPTAN1,TTPAL,VPS37A,DDX24,LSM12,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,MRPL36,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,PHF5A,COPS4,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,PPARG,CDK4,ANK2,MARCKSL1,PSMG1,LAMA2,KCNH2,ODC1,DLST,CRYBG3,LSG1,CXADR,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,PTP4A2,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,OLFM2,PAPD4,UPK3B,SUCLG1,ARID2,NDUFAF2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,KLF4,ATG7,INTS9,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,SNAPC5,AP4S1,LRRIQ1,MON1A,SMARCAD1,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,SMPDL3B,POLR3A,DKK1,CDH24,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,TAF12,NR2F2,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,CFD,HIC2,NRP1,TNFRSF10D,WDR66,BLMH,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,CDC42EP2,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,PRPF39,SSR4,PDCD5,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,FDFT1,EXOSC2,IFNGR2,KIAA1143,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,SEC31A,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,NOP56,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,SERP1,SNCA,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,G6PD,MBTD1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,SDCBP2,DYNC2H1,CELF1,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,PACS1,BMS1,KLF6,GUF1,SLC23A2,RETSAT,DDX50,IREB2,ZNF155,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,IMMP2L,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,SCART1,ZCCHC8,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,CCDC124,ZCCHC7,PRF1,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,FNBP1L,TBCK,PDE9A,N4BP2L2,TCF12,DMXL2,CHMP2A,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,COBLL1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,AUP1,MAML3,NARS2,NPW,ANTXR2,PRAME,METTL2A,GRHL3,ATXN1,MRRF,METTL15,DKC1,EDEM2,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,CMTM8,PDE4B,VPS45,ATF7IP,IGF2BP2,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,ZNF324B,PDE2A,EIF5B,NAALADL2,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,LYRM5,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,DCUN1D5,C10orf76,RBM28,TMSB4X,STOML2,DLEU1,DDX3X,BRCA2,SUPT4H1,TMEM139,FIS1,RBP1,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,CEP63,TMEM136,MTHFD2L,LSM10,MALL,GARS,KRT7,STAMBP,FAM111B,NPM3,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,WDR37,JMJD6,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,TMSB10,PVRL3,ACAP3,ARHGAP1,HNRNPM,SOX6,NUDC,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,R3HDM2,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,PPCDC,UBAP2L,ZNF85,RAN,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,ZNF124,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,PEX1,KIF16B,GLS,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,HSD17B10,TRIM15,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,ATXN7,FAM135A,ITPRIPL1,SPAG9,SYNCRIP,PALB2,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,HMBS,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,RSL1D1,RNF24,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,C15orf40,CYB5D1,HIRIP3,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,C1QTNF1,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,NFASC,ZNF18,PUS1,ZNF589,AP2S1,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,C14orf159,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,CWC27,HIST2H3D,PRICKLE2,GREB1,DDX31,SELT,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,MKX,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,RWDD2B,ITGB4,RPS6KC1,MIPOL1,GCSH,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RPS16,RNF111,VPS52,PAK1IP1,ME1,PRADC1,CEP135,MEIS3,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,SRRD,NSF,ZZEF1,D2HGDH,RIOK3,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,RTTN,PPDPF,TBKBP1,PTCD2,AMOTL1,TRPM2,LIN28B,SPATA2L,URB2,RIBC2,HFM1,SPRYD7,OLA1,C1QTNF7,KLHL18,SPATS2L,AP1B1,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,GALK2,MED16,TBC1D16,POLG2,STK10,DHX57,DCBLD2,VDR,HTR7,DNAJA3,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,SCAMP3,CA11,UTP14A,TTC27,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,MAD2L2,NEDD4,ZNF239,ZNF483,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,MMAA,NOP58,ECH1,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,BRWD3,RABEP1,SLC43A1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,ANKRD18A,SIRT2,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,SMARCB1,RTN1,ZNF804A,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,NDUFA6,OGG1,TRIM14,LONP1,PRKACB,TRIP13,TIMM50,LAMA4,ZBTB17,GPM6A,TRIM13,TXLNG,ZNF680,SLC38A1,CMIP,LVRN,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,COPS6,ZNF397,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,ETFB,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,GLTP,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,ZBTB24,ZNF706,ASH1L,PCNT,MMRN2,CELSR3,SLC5A5,MYO7A,ST7L,SLC9B2,CSTA,UBTD2,GBF1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,SLC25A11,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,NBR2,DNAJA4,SULT1C2,SH2D3A,DBF4,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,PPP1R1C,MFSD10,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,TTC17,UTS2,AMOT,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PPP1R21,PSMC3IP,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,NAPEPLD,TARS,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,SLC16A10,HRH1,CTXN1 |
| 9.068e-07 | -13.91 | adenocarcinoma | COSMIC cancer mutations | adenocarcinoma | 17602 | 2274 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,LDOC1L,USPL1,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,WDR26,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,C16orf52,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,RBFOX2,LPCAT2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 9.357e-07 | -13.88 | breast | COSMIC cancer mutations | breast | 17278 | 2247 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,MFHAS1,FAM49A,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,ATF7IP,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,RABGAP1L,FAAH2,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 9.449e-07 | -13.87 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | 487 | 100 | 17758 | 2279 |
CGN,TRIM16,NPAS2,ZBTB37,TNFRSF21,LPCAT2,MYH9,COBLL1,NBEAL1,S100A10,ZKSCAN1,NBEA,ME1,BCAP29,CDK6,LYST,MOSPD1,PTPRK,DBN1,PHLDB2,SESN2,MIOS,LIMA1,PPARG,EXOC6B,TFPI,GRHL3,MSRB3,MCL1,CCNDBP1,SOX4,ZSCAN2,ENC1,DDX60,PLIN2,SKIL,SMAD3,TCF7L1,MSX2,GATA6,TOM1L2,PAM,AHNAK2,ADAM9,SLC4A7,ABCC3,PPP3CC,GALNT10,ANXA2,SYNPO,MID1,KLHL24,EFNB2,UNC13D,FN1,EGR1,CLK1,ARL15,RCAN1,ZFP36L1,DNAJC22,TGFB2,TGFBR2,DDIT4,NAMPT,ZNF561,ZNF354A,SCN1B,IFIT5,MAP3K14,ERRFI1,SAMD4A,KDM6B,KDM5B,CRIM1,ZNF654,TRA2A,RAP1GAP2,ARID5B,TPM4,PTPN12,FERMT2,PHACTR2,PACS1,PALLD,KLF6,EVI5,DKK1,BAZ2B,PDLIM1,GADD45A,PMEPA1,CSRNP1,ARHGAP12,RPS6KC1,PDLIM5,FNBP1L,MMP16,PDE9A,DDIT3 |
| 9.595e-07 | -13.86 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | 1028 | 184 | 17775 | 2278 |
IMMP2L,ATRX,SLC25A21,CACNA1H,RNF43,PRKCA,NUP160,NOS1AP,TOM1L1,PCDH7,EXOC1,ECM1,YLPM1,GPATCH1,POLR3B,ETV1,SPAG6,CARM1,ZNF646,TBC1D8,CCDC57,SETD1B,PTPRM,KATNAL1,GPCPD1,KIF15,LAMA2,KMT2C,SON,TMEM132B,MSRA,BRCA2,CCNT1,MPV17,CSMD3,DPP4,DNAH2,RIOK1,TPM1,USP15,VIPR1,FOXO1,SEC24D,ANKRD17,TAF1,ITFG1,TRIO,NHS,OPHN1,SLC1A1,MTUS1,IGF2BP3,DOPEY1,UBE3A,MCAM,ENTPD5,SLC38A5,CEP290,PDE10A,CCDC112,ZCCHC7,AGL,SIK3,PRDM16,PCCA,EPS15L1,JMJD1C,RAP1GAP2,RYR2,ST6GALNAC3,SYT1,AGAP1,VAC14,TBC1D2,PRPF40B,GRIK4,LRP1B,UBAP2,TASP1,BICD1,ZCCHC6,SNX24,TMEM117,DTD1,CNOT6,ARHGAP12,HMBS,NAPA,PDE9A,COG5,VMA21,RTTN,TRPM2,DNM3,SYT17,PAPD4,ARID2,NPAS2,URB2,ACTR3,LPCAT3,PTPRG,TIGD1,RADIL,PIBF1,EEA1,STAM,PLXNB1,PDE3A,KDM1A,ZNF827,BRE,ERI1,NUP133,SNTG2,ITGAX,AHCYL1,PLEKHA4,CDK12,IPO11,CTC1,LYST,KMT2D,FAM172A,ZNF480,SATB2,MARCH6,TTC28,ERC1,SMAD3,ARHGAP21,RANBP2,ASTN2,PEMT,CAMKMT,TSSC1,RNF130,MID1,METTL2B,SMG1,PARD3,LRCH1,COMMD10,BRAF,AUH,DYM,DBF4,C1orf226,ZNF280C,VARS,SEMA3E,MON2,IKBKAP,RSRC1,MBNL1,NEDD4,PTPN2,COMMD9,PVRL3,DSG2,CD44,LDLRAD3,SOX6,KDM6B,AGPAT4,WDR18,PPP1R21,ARHGAP39,ARHGEF12,NAALADL2,ARMC3,SMPDL3B,CCDC150,OXSR1,BAZ2B,IREB2,MPP7,BCAS3,ATM,SORCS2,ITGB4,BRWD3,RPS6KC1,MMP16 |
| 9.612e-07 | -13.86 | purine ribonucleotide binding | molecular function | GO:0032555 | 1827 | 307 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,RAPGEF4,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,KIF16B,PEX1,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,SARS,TTN,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,PDE10A,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,PDE4A,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,IRAK2,DNAH17,HK2,RRAGA,BRSK2,TBCK,DDX10,PRKAR2A,SUCLG1,PAPD4,MYO7A,RIPK1,SMARCA4,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,TPK1,RAD54B,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,PDE4B,TKFC,ARFIP2,VARS,APRT,CSNK1A1,PIP4K2A,MFHAS1,GFM2,PRKCH,GART,DDX31,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,DHX34,TEX14,MARS,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 9.708e-07 | -13.85 | BENPORATH_MYC_MAX_TARGETS | MSigDB lists | BENPORATH_MYC_MAX_TARGETS | 752 | 142 | 17758 | 2279 |
PTP4A1,PRKCSH,PRKAB2,TNFRSF21,SRSF2,SREBF2,ATP5G2,SLC39A7,ANAPC10,VPS52,ZNF85,POLE3,KDM5C,NDUFA6,HCFC2,ZNRD1,CDK6,TRIP13,SPAG6,TMPO,METTL1,GDAP1,ATF4,ABCC4,NR6A1,HARS,AP4B1,TCEB3,KIF15,ATG12,PSMG1,TIMM44,PYCR1,DDX3X,SLC7A1,PER1,ARL6IP5,DMTF1,DCTN3,SARS,UBXN1,RNF141,ELL,MLX,USPL1,COPS3,MCM5,ALDH18A1,GMDS,PRMT5,CNOT4,PPA1,MTHFD1,NAA38,TIMM8B,CRADD,SIGMAR1,TLE3,WBSCR22,PSMA1,SUPT5H,PWP1,MGAT2,MYBBP1A,TRAP1,SRP68,RRAGA,CNDP2,DDX10,COG5,TCF12,MAP2K5,SUCLG1,BIRC6,RPS29,ACTR3,LAGE3,NDUFB5,EEA1,NDUFB3,CAD,VGF,CLCN6,ZNF142,ETF1,AHCYL1,HTRA2,SAP30,PMS1,MPP6,DDX41,PDK1,PCMT1,POU2F1,GNL1,SERP1,MAT2A,EXO1,SMAD3,CDC16,RBBP8,KPNA3,TIMM17A,CEBPZ,FTSJ1,H2AFX,CBWD1,ALKBH1,SLC25A11,RPS6KB1,MED20,USP11,SCAMP3,ARFIP2,RPS6KA5,MBNL1,NPRL2,NDUFV1,CWC27,DCTN4,POLR1B,ULBP1,PFKFB4,AP4S1,KDM5A,LDHA,MARS,TMEM187,UBE2K,POLR3A,POLR3G,YIF1A,CACNB1,HERC1,ATM,EIF2S1,NCBP2,POLR1C,NFKBIB,IGBP1,ZAK,SLC43A1 |
| 9.856e-07 | -13.83 | MORF_DDB1 | MSigDB lists | MORF_DDB1 | 234 | 57 | 17758 | 2279 |
NCOR2,SARS,ANKRD17,DDX18,PRPF31,PRKCSH,FAM189B,PTPRA,KHDRBS1,NDUFB5,CSNK2A1,VARS,HLTF,XPO7,TTI1,PARN,RING1,TERF2IP,CAD,ATXN2,AHCYL1,TOMM34,TRIP13,MPST,SNAPC5,KDM3B,TSTA3,ATG9A,SFSWAP,PARP2,WDR18,MARS,BMS1,RABAC1,MCM2,DENND4A,EHBP1,SERP1,ABCF1,POLR2A,RERE,MFN2,YIF1A,SEC31A,PWP1,EPRS,TRRAP,CHD3,TP53BP1,EIF2S1,NCBP2,SLC25A11,PRPF4,SCARB1,NFRKB,COPS6,XPO6 |
| 1.001e-06 | -13.81 | transcription factor activity, transcription factor binding | molecular function | GO:0000989 | 581 | 117 | 16491 | 2164 |
TRERF1,KMT2E,RBFOX2,PPARGC1B,SMARCA4,BCOR,BIRC2,LPIN1,KDM1A,SKI,SMARCB1,SRSF2,JAZF1,LPIN2,RELB,ZEB1,ZNF85,RAN,HCFC2,TRIP13,CASP8AP2,CARM1,SAP30,MAML3,AEBP2,ATF4,SIRT6,PPARG,MED27,MINA,MED16,SUPT20H,BRCA1,SOX4,TAF9B,BATF3,TAF2,DYRK1B,SKIL,MSX2,RBBP8,TRRAP,SMARCC1,ELP2,SUFU,TP53BP1,PER1,KLF4,COPS5,HIPK2,MKL2,PQBP1,PUS1,FUS,MED20,BEND6,RFXAP,PTPN14,HMGA2,WDR75,NCOR2,FOXO1,JUP,TAF1,ZHX3,TCF3,HES6,MED13L,MED18,ATF7IP,TRIM22,BHLHE40,ARID1B,SFR1,TADA3,SNW1,SUB1,HR,BUD31,MED24,YBX3,ZNF710,PRMT5,NRIP1,KDM5B,APEX1,FGF2,PRDM16,KDM5A,ARID5B,PSMC3IP,SMARCD3,WWC1,ARID1A,SRA1,NR2F1,RERE,ZNF783,TRIB3,NSD1,SRCAP,MYBBP1A,GTF2A1,PDLIM1,HIF1A,SPEN,MED15,TAF4,TBPL1,NCOR1,TBL1X,TAF12,NFKBIB,NR2F2,DDIT3,N4BP2L2,KAT6A |
| 1.021e-06 | -13.80 | RNA_PROCESSING | MSigDB lists | RNA_PROCESSING | 169 | 45 | 17758 | 2279 |
SARS,PRPF31,KHDRBS1,SF3A3,FARS2,NOL3,ZNF346,AARS,PABPC4,IGF2BP3,NOP56,SNW1,SRSF2,BCAS2,PHF5A,INTS7,INTS12,GEMIN4,CELF1,CPSF3,FBL,PABPC1,CPSF3L,SF3A1,SRPK2,SCAF11,METTL1,EXOSC2,RNMT,SFSWAP,TRA2A,DKC1,NOP58,SPOP,GEMIN5,BICD1,SYNCRIP,HNRNPR,INTS5,HNRNPH3,LUC7L3,INTS9,NCBP2,ZRANB2,NOLC1 |
| 1.022e-06 | -13.79 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | 644 | 125 | 17758 | 2279 |
DDX18,RBFOX2,PSTPIP2,ACTR3,LPCAT3,AARS,KDM1A,LPIN1,EDC3,IDI1,DUS4L,PPID,MAD1L1,HIRIP3,SLC27A5,VCL,TRIP13,TIMM50,SRPK2,RFC4,GARS,RFC3,DDX41,ABCC4,SKAP2,SLC38A1,SKIV2L2,TFPI,KIF15,WDHD1,BRCA1,DKC1,MCM2,ODC1,RAD54B,CHAF1A,GNAI1,WARS,TIMM44,PES1,PAF1,LSS,INSIG1,DCXR,LSM14A,LUC7L3,DPP4,ACP1,SEMA3C,PRPF4,PUS1,TPM1,NOLC1,BLMH,ECHDC1,MEF2C,HMGA2,SHQ1,TRIP6,UTP14A,TTC27,CAMK1,STXBP6,SF3A3,TIMM10,INPP1,ETFB,NDUFV1,EIF2S2,CTNNBL1,PTRF,MCM5,SEC24C,ATIC,DSG2,KDELC1,TIMELESS,SHMT2,RDX,PTGS1,NOC3L,EXOSC4,LARP4B,NRIP1,COQ3,ATP6V0D1,PPA1,SERBP1,HNRNPM,SLC25A1,NUDC,FDFT1,HMGCR,FADS1,ARNTL2,VOPP1,GTF2H3,EXOSC2,PSAT1,ELOVL6,ABCF2,ELP3,PSMC3IP,ARID5B,LDHA,PSMA1,MRPS10,RANGAP1,PTK2,EIF5B,RPA1,RDH11,PGD,TSR1,EPRS,TRAP1,CDK9,HNRNPH3,FDPS,EIF2S1,SQLE,DNAJC12,MACROD1,DHCR7,GALE |
| 1.066e-06 | -13.75 | RNA polymerase complex | cellular component | GO:0030880 | 124 | 36 | 17570 | 2233 |
PAPD4,TAF1,POLR1A,MED18,CDC73,TADA3,POLR3D,INTS7,TAF3,GTF2H1,CTR9,INTS12,POLR3B,POLR1B,ZNRD1,POLR1E,CPSF3L,GTF2H3,WDR61,POLA1,POLR2A,POLR3A,POLR3G,TAF9B,PAF1,TAF2,TRRAP,GTF2A1,INTS5,POLR3E,TAF4,TBPL1,INTS9,CRCP,TAF12,POLR1C |
| 1.075e-06 | -13.74 | RPA2 (replication protein A2) | protein interactions | 6118 | 428 | 97 | 16036 | 2270 |
USP7,ATP6V1A,RBFOX2,MYH9,HLTF,AP1B1,RPAIN,PELP1,HNRNPA3,KDM1A,PABPC4,BCAS2,ATRIP,SEH1L,TMPO,SF3A1,PRPF19,RFC4,RFC3,LIMA1,SKIV2L2,PARP2,RAB7A,HSPA5,WDHD1,CAV1,MCM2,DSP,RAB10,YTHDF2,GEMIN5,DDX3X,DNTTIP1,AHNAK,TP53BP1,HNRNPR,FUS,ANXA2,COPS6,ZNF598,TMEM33,SCAMP3,FN1,UTP14A,XPC,ZCCHC8,KHDRBS1,UBXN1,RTN4,CEP126,CSNK1A1,CLINT1,RMI1,HIST2H2AB,EIF2S2,MCM5,GTF2H1,POLR1B,GEMIN4,CELF1,FBL,PABPC1,ATP6V0D1,HNRNPM,TERF2,SPTAN1,MTHFD1,MSI2,GTF2H3,APEX1,RB1CC1,POLA1,TOP3A,LDHA,IMPDH2,MEN1,SYMPK,HERPUD1,UBC,RPA1,DYNC1H1,TSR1,TPD52L2,EPRS,SRBD1,SYNCRIP,ORC5,MSH3,EIF2S1,ATM,PURB,C7orf50,RBM26,KIAA0196,PFDN2,WDR33,NAPA |
| 1.080e-06 | -13.74 | ribonucleotide binding | molecular function | GO:0032553 | 1843 | 309 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,RAPGEF4,IDH3G,TYW1,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,PDK4,ACTR3,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,PDE10A,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,PDE4A,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,HK2,RRAGA,BRSK2,TBCK,DDX10,PRKAR2A,SUCLG1,PAPD4,MYO7A,SMARCA4,RIPK1,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,RAD54B,TPK1,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,PDE4B,TKFC,ARFIP2,VARS,APRT,CSNK1A1,PIP4K2A,MFHAS1,GFM2,PRKCH,GART,NDUFV1,DDX31,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,DHX34,TEX14,MARS,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 1.104e-06 | -13.72 | peptidyl-lysine modification | biological process | GO:0018205 | 288 | 67 | 16441 | 2138 |
ASH1L,TRIM16,KMT2E,PLOD1,SIRT2,NUP43,NUP160,RING1,PHC2,NUP133,KANSL1,RNF2,POLE3,KMT2A,SEH1L,KAT8,KMT2D,BRD4,SETD1B,BAZ2A,EHMT1,SUMO3,BRCA1,SETD7,KMT2C,NUP214,DOT1L,RANBP2,BRCA2,TRRAP,NSMCE1,NSMCE2,PER1,CAMKMT,BMI1,XRCC4,SETD6,YEATS2,HERC2,EP400,WDR75,TAF1,XPC,TCF3,JMJD6,CHD5,POM121,TADA3,SUV39H2,USPL1,CTR9,MED24,STAG1,WDR61,SETD2,ELP3,ATAT1,SCMH1,MEN1,RPA1,NSD1,SRCAP,EHMT2,SENP3,TAF12,SMYD3,KAT6A |
| 1.134e-06 | -13.69 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 191 | 49 | 17758 | 2279 |
PTCD2,AK2,PRPF31,PLRG1,HDDC2,PABPC4,FDX1,MRPS11,FARSA,GART,MYC,ETF1,PCK2,ALDH18A1,FXN,VCL,YARS,NAA35,TRIP13,ELOF1,SF3A1,HMGCR,TIMM8B,GARS,WDR61,ITPA,CDK4,TBRG4,MARCKSL1,PSMG1,MARS,PITPNB,ABCF1,TARS,MAT2A,MRPL36,STOML2,PGD,EXO1,MTHFD2,KPNA3,G6PD,LUC7L3,CUL2,ACP1,SQLE,NDUFS5,BLMH,GCSH |
| 1.158e-06 | -13.67 | regulation of nucleic acid-templated transcription | biological process | GO:1903506 | 3475 | 537 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,ZNF148,FNIP2,KDM5C,HMBOX1,GNL3,EHMT1,NFIA,KRBOX4,RFX2,ZNF197,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ZNF326,MED24,PRMT5,ZNF518B,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,TASP1,GTF2A1,PDLIM1,EHMT2,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ZKSCAN1,WAC,KMT2D,ZNF480,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,FUS,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,TADA3,SNW1,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ATF4,AEBP2,ZNF124,PPARG,ZNF414,BAZ2A,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,E2F4,PER1,TNFRSF1A,DLX2,BEND6,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,TBPL1,ZNF430,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ZFP37,RNF2,PRMT3,KAT8,KDM3B,PCGF3,DDX41,ZNF251,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,ZNF589,ZNF507,MAP3K13,RFX1,AGO2,FOXP1,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,SNAPC5,TRNP1,ZNF654,SMARCAD1,FOXN3,ZMYM5,HIST1H4J,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,GABPB2,MGA,LPIN1,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,ZHX3,CENPB,PID1,GTF2IRD1,CHD5,HR,ZNF586,MYC,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,IGSF1,RING1,BLOC1S2,TERF2IP,CHD7,ZNF827,KDM2A,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,SATB2,MED16,PNN,SETD7,ERC1,ZBTB25,SNCA,BAZ1A,VDR,CAMK2D,DNTTIP1,MSX2,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,YBX3,MBTPS2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,POLR2A,ZFP62,ZNF155,BRWD3,DDIT3,KAT6A,ZNF76,KMT2E,ATRX,UBN1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,ZBTB17,DEAF1,TRIM13,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,SUFU,GATA6,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,N4BP2L2,ZBTB24,TCF12,ZNF706,ASH1L,DLL4,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,HEATR1,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,KDM5B,ZNF821,FGF2,TEAD1,KDM5A,PSPC1,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NFKBIB |
| 1.162e-06 | -13.67 | UDAYAKUMAR_MED1_TARGETS_DN | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_DN | 224 | 55 | 17758 | 2279 |
KLHL24,PCNT,FEM1C,RHOBTB1,CCDC53,ST6GAL1,UROD,TRIO,ID2,RCAN1,FOSL2,DENND3,GDPD5,BMP6,PCDH7,C6orf48,DNAJB6,FMNL1,JOSD1,TTC17,ZMYM2,SPTAN1,PEA15,IFRD1,MSX1,DNMBP,PTBP2,RB1CC1,TLE3,SFSWAP,UPP1,TFPI,ARID5B,MAP7D1,PNN,SNAP25,PDE2A,PALLD,GPNMB,AGAP1,USP36,DKK1,SPAG9,ZDHHC11,GADD45A,ZZEF1,KLF4,HSPBAP1,HERC1,ARL4A,ABHD3,RIOK3,HSPB8,TPM1,LAMA5 |
| 1.177e-06 | -13.65 | RNA modification | biological process | GO:0009451 | 117 | 35 | 16441 | 2138 |
CTU2,AARS2,LAGE3,PARN,AARS,NOP56,METTL16,PUS3,DUS4L,TRMT13,TRMU,ALKBH8,FBL,TRMT10A,TRMT12,FTSJ3,ADARB1,METTL1,RNMT,TYW1,ELP3,METTL2A,METTL15,DKC1,NOP58,PUSL1,EPRS,DUS3L,TRMT5,ADAT2,FTSJ1,TRMT2A,CDKAL1,PUS1,METTL2B |
| 1.204e-06 | -13.63 | BARD1 (BRCA1 associated RING domain 1) | protein interactions | 580 | 256 | 65 | 16036 | 2270 |
BCCIP,OLA1,AP1B1,UBR5,ZNF121,HNRNPLL,RPP30,IDI1,SRSF2,BRE,NSRP1,CPSF3,SRRM2,CDK12,SRPK2,AKAP8L,NPM3,TCEB3,POU2F1,PNN,BRCA1,FKBP3,DHX57,GEMIN5,BRCA2,RBBP8,KPNA3,CHD3,CCNT1,LUC7L3,E2F4,HIC2,H2AFX,ACP1,BRCC3,MCM6,UBXN1,WDR26,MLH1,IKBKAP,PARN,FKBP1A,KRI1,UBE3A,GEMIN4,MICAL3,NOM1,TOP1,SCAF11,EXOSC2,WDR61,TRA2A,SUPT5H,UBE2K,CASC1,POLR2A,UBE2E1,TSR1,DDX50,CLASRP,CDK9,MSH3,WDR33,PGAM5,LRRC41 |
| 1.210e-06 | -13.62 | RNA_BIOSYNTHETIC_PROCESS | MSigDB lists | RNA_BIOSYNTHETIC_PROCESS | 627 | 122 | 17758 | 2279 |
TCF12,ZNF254,ZNF76,ASH1L,TRERF1,UBN1,NPAS2,ATRX,PPARGC1B,PBX1,BCOR,FOSL2,SNAPC4,GABPB2,MAP2K3,SMARCB1,RRN3,NRF1,SREBF2,ZFHX3,PHF5A,JAZF1,ZEB1,ZNF148,CHD2,ETV1,HCFC2,TRIP13,CARM1,MAML3,DEAF1,ATF4,TFCP2,NR6A1,PPARG,MED27,TCEB3,CUX1,HDAC8,MED16,BRCA1,BATF3,UBTF,SKIL,SMAD3,TAF2,DYRK1B,RBBP8,SUPT4H1,SUFU,GATA6,SMARCC1,ELP2,CHD3,CCNT1,COPS5,KLF4,MKL2,CEBPZ,ARNTL,PQBP1,TNFRSF1A,NFRKB,RUNX1,MED20,TROVE2,HMGA2,FOXO1,ZHX3,PAX2,TCF3,TRAK1,NFX1,ATF7IP,RSF1,TRIM22,IKBKAP,RPS6KA5,FOXO3,BMP6,TADA3,ABL1,SNW1,SUB1,ELL,PTRF,ZNF354A,VPS72,MYC,BUD31,GTF2H1,MED24,NRIP1,POLR1E,SNAPC5,KDM5B,PRIM2,RREB1,APEX1,KDM5A,FOXN3,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,MEN1,SUPT5H,TCF7L2,POLR3G,SRCAP,NSD1,MYBBP1A,HIF1A,CDK9,TBX3,RBPJ,NCOR1,POLR1C,NR2F2,DDIT3 |
| 1.211e-06 | -13.62 | REGULATION_OF_RNA_METABOLIC_PROCESS | MSigDB lists | REGULATION_OF_RNA_METABOLIC_PROCESS | 465 | 96 | 17758 | 2279 |
ZNF254,TCF12,ZNF76,TRERF1,UBN1,NPAS2,ATRX,PPARGC1B,PBX1,BCOR,FOSL2,GABPB2,MAP2K3,SMARCB1,NRF1,PHF5A,SREBF2,ZFHX3,JAZF1,ZEB1,ZNF148,CHD2,HCFC2,CARM1,MAML3,ATF4,PPARG,TFCP2,NR6A1,MED27,TCEB3,CUX1,HDAC8,BRCA1,SMAD3,UBTF,DYRK1B,SUPT4H1,RBBP8,SUFU,SMARCC1,ELP2,GATA6,CHD3,KLF4,MKL2,ARNTL,TNFRSF1A,PQBP1,MED20,RUNX1,HMGA2,FOXO1,ZHX3,TCF3,TRAK1,NFX1,ATF7IP,RSF1,TRIM22,IKBKAP,RPS6KA5,FOXO3,BMP6,TADA3,ABL1,SUB1,SNW1,ZNF354A,MYC,VPS72,BUD31,GTF2H1,NRIP1,PABPC1,KDM5B,RREB1,FOXN3,JMJD1C,ELP3,ARID5B,SMARCD3,PRDM1,ARID1A,SUPT5H,MEN1,TCF7L2,POLR3G,NSD1,SRCAP,MYBBP1A,HIF1A,TBX3,RBPJ,NR2F2,DDIT3 |
| 1.232e-06 | -13.61 | ABCF2 (ATP binding cassette subfamily F member 2) | protein interactions | 10061 | 35 | 17 | 16036 | 2270 |
WDR36,DDX18,SIRT6,NAT10,BRCA1,CCNL2,DKC1,EIF5B,ISG15,NOP56,DDX3X,SNW1,SHMT2,UPF2,FUS,POLR1C,MTHFD1 |
| 1.244e-06 | -13.60 | ribonucleoside binding | molecular function | GO:0032549 | 1798 | 302 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,POLR3B,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,KIF16B,PEX1,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,SARS,TTN,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,HK2,RRAGA,BRSK2,TBCK,DDX10,SUCLG1,PAPD4,MYO7A,RIPK1,SMARCA4,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,TPK1,RAD54B,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,TKFC,ARFIP2,VARS,APRT,CSNK1A1,MFHAS1,GFM2,PIP4K2A,PRKCH,GART,DDX31,POLR1B,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 1.255e-06 | -13.59 | nucleoside binding | molecular function | GO:0001882 | 1805 | 303 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,POLA1,PCCA,EIF4A2,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,PDK4,ACTR3,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,POLR3B,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,IRAK2,DNAH17,HK2,RRAGA,BRSK2,TBCK,DDX10,SUCLG1,PAPD4,MYO7A,RIPK1,SMARCA4,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,RAD54B,TPK1,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,TKFC,ARFIP2,VARS,APRT,CSNK1A1,MFHAS1,GFM2,PIP4K2A,PRKCH,GART,DDX31,POLR1B,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 1.262e-06 | -13.58 | transferase activity, transferring one-carbon groups | molecular function | GO:0016741 | 220 | 55 | 16491 | 2164 |
ASH1L,KMT2E,NSUN6,CIAPIN1,METTL16,CAD,GART,SUV39H2,TRMT13,ATIC,TRMU,ALKBH8,METTL8,SHMT2,FBL,TRMT10A,PRMT5,KMT2A,COQ3,PRMT3,FTSJ3,CARM1,METTL1,KMT2D,SETD1B,RNMT,ALDH1L2,SETD2,EHMT1,METTL23,METTL2A,PCMT1,WBSCR22,METTL15,PRDM1,SETD7,MEN1,METTL22,KMT2C,MTR,DOT1L,NSD1,EHMT2,TRMT5,METTL6,PEMT,CAMKMT,FTSJ1,TRMT2A,TRMT10B,NDUFAF5,SETD6,SMYD3,METTL2B,GCSH |
| 1.289e-06 | -13.56 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 363 | 79 | 17758 | 2279 |
SNX27,DNM3,CUL4A,PCNT,FANCD2,PBX1,PRKCA,TMEM150C,JAG1,LONRF2,PMAIP1,NUP133,ANKRD11,HIRIP3,MET,CCDC121,MGLL,LYST,TMPO,CEP128,SAP30,PHLDB2,TFPI,KIF15,PREX1,SLC35F2,AKAP13,S100A16,BTBD11,VDR,BRCA2,TOM1L2,TRMT5,SH3RF1,ARL4A,H2AFX,HSPB8,ADAM9,SLC4A7,GALNT10,ANXA2,RFXAP,SH2D3A,DLGAP4,ID2,IGF2BP2,WDR26,DNAJC22,RPS6KA5,RMI1,MTUS1,CHN1,C6orf48,PTRF,DSG2,STC2,SDCBP2,CD44,CAV2,TOMM34,MTHFD1,NT5E,ARNTL2,PXN,LAMC1,MYO10,POLA1,KLF6,MBNL2,PDE3B,ANGPTL4,SRCAP,C6orf141,PXDN,DSC2,PMEPA1,HK2,NR2F2,SMYD3 |
| 1.344e-06 | -13.52 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | 76 | 26 | 17758 | 2279 |
FADS1,SLC3A2,GARS,MVK,LDHA,GTF2IRD1,MARS,CAV1,BMP6,ATP5D,RPP30,EIF2S2,GART,INSIG1,MYC,PAM,HK2,ACP1,SQLE,HMBS,YARS,BMI1,LONP1,HMGCR,TBC1D8,FDFT1 |
| 1.372e-06 | -13.50 | RRS1 (ribosome biogenesis regulator homolog) | protein interactions | 23212 | 74 | 27 | 16036 | 2270 |
ADARB1,SNU13,NIFK,CUL7,DDX18,WDR74,SKIV2L2,GNL3,SIRT7,NFIA,RSL1D1,BMS1,NOP58,PUM3,NOP56,RANBP2,DDX56,MYBBP1A,SURF2,ADNP,POLR3B,FBL,NOLC1,NMD3,ZC3H3,FTSJ3,HNRNPM |
| 1.580e-06 | -13.36 | CATTTCA,MIR-203 | MSigDB lists | CATTTCA,MIR-203 | 277 | 64 | 17758 | 2279 |
PTP4A1,TCF12,ARID2,C16orf45,ADAMTS6,PTPRG,PRKCA,SYNJ1,RPGRIP1L,LPIN1,ZNF608,RAP1A,UBR1,SOCS6,NBEA,GPATCH1,JOSD1,ETV1,PRPF19,GRHL3,R3HDM1,RAB10,C1orf122,INSIG1,ARNTL,C3orf35,FKBP5,MAGI1,ZNF532,LPP,MEF2C,EGR1,SEC24D,KHDRBS1,SESTD1,ID2,CSNK1A1,MBNL1,SPIRE1,ABL1,PRICKLE2,COPS7B,SELT,AMOT,FMNL2,C12orf4,TSHZ1,COL17A1,WDFY3,RAPGEF4,FAM126B,ARID1A,MBNL2,TASP1,VCAN,SPEN,PURB,ATM,ZRANB2,ARHGAP12,MBD6,ADK,PDSS2,LMBRD2 |
| 1.598e-06 | -13.35 | CTTTGTA,MIR-524 | MSigDB lists | CTTTGTA,MIR-524 | 419 | 88 | 17758 | 2279 |
CELSR3,CNTNAP3,KIF5A,SBF2,ADAMTS6,NECAP1,TNKS1BP1,SLC30A7,CHD7,SRSF2,JAZF1,NBEA,RNF111,SEH1L,DBN1,SOBP,PCGF3,GPM6A,TCEB3,NFIA,GNL1,SOX4,KRTCAP2,SON,SERP1,GNAI1,SKIL,SMAD3,ADNP,ASTN2,LSM14A,ARL4A,CSMD3,RIOK1,RUNX1,MTCH1,MEF2C,HMGA2,PRPF38B,EP400,KHDRBS1,SESTD1,NHS,SLC25A12,QSER1,FOXP1,GIGYF2,FKBP1A,PTPN2,LDOC1L,ATXN2,LTN1,NLGN3,CELF1,ANP32B,NAV3,TSHZ1,GATAD2B,DDHD1,ADAMTSL3,KCNQ3,WDFY3,TEAD1,FOXN3,SMARCAD1,JMJD1C,RAP1B,ARHGEF12,RSBN1,PRDM1,PDE2A,MBNL2,NOP58,TCF7L2,ZNF655,MGAT2,LRP1B,BAZ2B,SERF2,GADD45A,L3MBTL3,SPEN,TAF4,TAF12,TBL1X,NR2F2,FNBP1L,MB21D2 |
| 1.683e-06 | -13.29 | GSE27786_LIN_NEG_VS_MONO_MAC_UP | MSigDB lists | GSE27786_LIN_NEG_VS_MONO_MAC_UP | 188 | 48 | 17758 | 2279 |
TCF12,DNAJA4,TTC27,DDX19A,SLC29A1,LIAS,AP1B1,PRKCA,ZMAT2,MFHAS1,ARID1B,KDM1A,FARSA,ESAM,CD96,PUS3,SACS,UBE3A,NOP16,CEP290,COPS3,WDR60,RDX,NOC3L,RPL22L1,IPO11,PRPF19,NIPSNAP1,CHD9,FAM172A,PDK1,WDR61,RNMT,SKIV2L2,TFPI,TBRG4,METTL15,MAT2A,POLR3G,TRRAP,INSIG1,ARL4A,FAM206A,PTRH2,TRMT2A,NCBP2,SRFBP1,USP15 |
| 1.724e-06 | -13.27 | DDX56 (DEAD (Asp-Glu-Ala-Asp) box helicase 56) | protein interactions | 54606 | 79 | 28 | 16036 | 2270 |
WDR36,SNU13,CUL7,DDX24,UTP14A,DDX18,SIRT7,RPS29,DKC1,NOP58,DHX57,PUM3,NOP56,DDX56,MPHOSPH10,EIF2S2,RPS16,MYBBP1A,DHX37,COPS5,CEBPZ,CUL2,RNF2,FBL,NOLC1,DDX10,SRP14,FTSJ3 |
| 1.740e-06 | -13.26 | NUCLEOPLASM | MSigDB lists | NUCLEOPLASM | 272 | 63 | 17758 | 2279 |
PRPF31,TAF1,NPAS2,TFIP11,PPARGC1B,HES6,SMARCA4,MED18,RSF1,IKBKAP,ARID1B,SNAPC4,RPAIN,GIT2,SMARCB1,SUB1,SRSF2,INTS7,NSRP1,JAZF1,INTS12,GTF2H1,ZNF148,GTF3C3,CPSF3,OGG1,CPSF3L,TIMM50,TOP1,SAP30,SCAF11,PPP1R9B,NR6A1,POLA1,ELP3,SMARCD3,WDHD1,ATXN1,HDAC8,MED16,ARID1A,APTX,DKC1,MEN1,SYMPK,POLR2A,CHAF1A,RPA1,POLR3G,GEMIN5,TAF2,TRRAP,SMARCC1,ELP2,TP53BP1,HIF1A,INTS5,CDK9,HIPK2,ARNTL,TAF4,INTS9,TAF12 |
| 1.741e-06 | -13.26 | TRANSCRIPTION_DNA_DEPENDENT | MSigDB lists | TRANSCRIPTION_DNA_DEPENDENT | 625 | 121 | 17758 | 2279 |
TCF12,ZNF254,ZNF76,ASH1L,TRERF1,UBN1,NPAS2,ATRX,PPARGC1B,PBX1,BCOR,FOSL2,SNAPC4,GABPB2,MAP2K3,SMARCB1,RRN3,NRF1,SREBF2,ZFHX3,PHF5A,JAZF1,ZEB1,ZNF148,CHD2,ETV1,HCFC2,TRIP13,CARM1,MAML3,DEAF1,ATF4,TFCP2,NR6A1,PPARG,MED27,TCEB3,CUX1,HDAC8,MED16,BRCA1,BATF3,UBTF,SKIL,SMAD3,TAF2,DYRK1B,RBBP8,SUPT4H1,SUFU,GATA6,SMARCC1,ELP2,CHD3,CCNT1,COPS5,KLF4,MKL2,CEBPZ,ARNTL,PQBP1,TNFRSF1A,NFRKB,RUNX1,MED20,TROVE2,HMGA2,FOXO1,ZHX3,PAX2,TCF3,TRAK1,NFX1,ATF7IP,RSF1,TRIM22,IKBKAP,RPS6KA5,FOXO3,BMP6,TADA3,ABL1,SNW1,SUB1,ELL,PTRF,ZNF354A,VPS72,MYC,BUD31,GTF2H1,MED24,NRIP1,POLR1E,SNAPC5,RREB1,APEX1,KDM5B,KDM5A,FOXN3,ARID5B,ELP3,JMJD1C,SMARCD3,PRDM1,ARID1A,MEN1,SUPT5H,TCF7L2,POLR3G,SRCAP,NSD1,MYBBP1A,HIF1A,CDK9,TBX3,RBPJ,NCOR1,POLR1C,NR2F2,DDIT3 |
| 1.765e-06 | -13.25 | GROSS_HYPOXIA_VIA_ELK3_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_DN | 151 | 41 | 17758 | 2279 |
CARS,EGR1,KIF5A,SLC2A1,CACNA1H,MYH9,RCAN1,BHLHE40,RPS6KA5,KCTD11,JAG1,ASNS,SLC7A11,MYC,ERRFI1,CD44,SCAF11,TSHZ1,IFRD1,ATF4,TSTA3,ALDH1L2,UPP1,JMJD1C,HSPA5,AKAP12,KLF6,RAD54B,GZF1,SKIL,SLC39A14,RARS,EPRS,MTHFD2,GADD45A,ZNF330,KLF4,CSRNP1,RIOK1,RBPJ,PDLIM5 |
| 1.800e-06 | -13.23 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_UP | 183 | 47 | 17758 | 2279 |
FBXO45,NDUFA5,SHQ1,PRPF31,C17orf80,URB2,PPARGC1B,ST6GAL1,DCP1B,HSD17B10,PIK3R4,WDR37,POP5,IKBIP,PDCD7,CIAPIN1,EDC3,NOP56,ZSCAN5A,PCYOX1L,DCTPP1,SRSF2,SUV39H2,ZNF561,TRIAP1,POLR3B,PRADC1,TRMT12,SNAPC5,IPO11,TSHZ1,WDR36,UTP15,ADSL,NAPEPLD,LYRM7,RPA1,POP1,FBXO21,ORC5,PTRH2,UMPS,RUNX1,POLR1C,FAHD1,HS2ST1,HRH1 |
| 1.857e-06 | -13.20 | regulation of RNA biosynthetic process | biological process | GO:2001141 | 3495 | 538 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,ZNF148,FNIP2,KDM5C,HMBOX1,GNL3,EHMT1,NFIA,KRBOX4,RFX2,ZNF197,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ZNF326,MED24,PRMT5,ZNF518B,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,TASP1,GTF2A1,PDLIM1,EHMT2,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ZKSCAN1,WAC,KMT2D,ZNF480,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,FUS,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,TADA3,SNW1,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ATF4,AEBP2,ZNF124,PPARG,ZNF414,BAZ2A,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,E2F4,PER1,TNFRSF1A,DLX2,BEND6,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,TBPL1,ZNF430,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ZFP37,RNF2,PRMT3,KAT8,KDM3B,PCGF3,DDX41,ZNF251,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,ZNF589,ZNF507,MAP3K13,RFX1,AGO2,FOXP1,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,SNAPC5,TRNP1,ZNF654,SMARCAD1,FOXN3,ZMYM5,HIST1H4J,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,GABPB2,MGA,LPIN1,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,ZHX3,CENPB,PID1,GTF2IRD1,CHD5,HR,ZNF586,MYC,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,IGSF1,RING1,BLOC1S2,TERF2IP,CHD7,ZNF827,KDM2A,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,SATB2,MED16,PNN,SETD7,ERC1,ZBTB25,SNCA,BAZ1A,VDR,CAMK2D,MSX2,DNTTIP1,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,YBX3,MBTPS2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,POLR2A,ZFP62,ZNF155,BRWD3,DDIT3,KAT6A,ZNF76,KMT2E,ATRX,UBN1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,TRIP13,ELOF1,ZBTB17,DEAF1,TRIM13,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,SUFU,GATA6,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,N4BP2L2,ZBTB24,TCF12,ZNF706,ASH1L,DLL4,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,HEATR1,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,KDM5B,ZNF821,FGF2,TEAD1,KDM5A,PSPC1,PSMC3IP,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,ZNF221,HSPA1B,RERE,ZNF708,CUL2,NCBP2,ZRANB2,NFKBIB |
| 1.903e-06 | -13.17 | MACROMOLECULAR_COMPLEX | MSigDB lists | MACROMOLECULAR_COMPLEX | 931 | 168 | 17758 | 2279 |
EIF3C,KIF5A,PPARGC1B,MRPL10,CACNA1H,NUP160,SNAPC4,SMARCB1,PHF5A,ATP5G2,ATG3,JAZF1,ANAPC11,ZNF148,NDUFA6,CDK6,PRKACB,TIMM50,SF3A1,NR6A1,CDK4,NOL6,KIF15,SUMO3,HDAC8,BRCA1,KRTCAP2,KCNH2,CHAF1A,GNAI1,ARPC3,TRRAP,BRCA2,DCTN3,TNNC1,TRIP6,PRPF31,TAF1,HES6,DPM3,RSF1,PDCD7,XPO7,KCNJ14,TIMM10,TGFBR2,ARID1B,NDUFS7,ABCA7,SUB1,CNST,EIF2S2,INTS7,CEP290,CACNB2,ATXN2,GTF2H1,GTF3C3,GEMIN4,AGL,CPSF3L,SCAF11,TIMM8B,LAMC1,KCNQ3,POLA1,ELP3,EIF4A2,BCS1L,PSMA1,LIG4,RNH1,ARID1A,EIF2A,SRA1,POP1,MYBBP1A,KPNA1,HIF1A,INTS5,CDK9,SRP68,PURB,SRP14,COG5,PAFAH1B1,NPAS2,ATP6V1A,ACTR3,VTI1A,PPP2R2A,MYH9,SPATS2L,RPP30,BRE,BCAS2,ACD,NUP133,SNTG2,INTS12,ITGAX,VCL,SAP30,RFC4,RFC3,EIF3J,ATXN1,MED16,DKC1,NUP214,SERP1,ERC1,EIF3H,ATP5D,SMAD3,TAF2,RANBP2,CAMK2D,KPNA3,ELP2,SMARCC1,HNRNPR,TIMM17A,COPS5,ARNTL,ITGA2,INTS9,BRCC3,EIF2B3,XRCC4,TROVE2,AP2S1,MID1,MAPT,BCKDK,MAP3K13,SF3A3,KIF5C,MED18,IKBKAP,MRPS11,SNW1,NDUFV1,HNRNPM,PPP1R9B,PXN,APEX1,KDM5A,KCNMA1,ABCF2,MRPS10,CCDC113,RANGAP1,IL6R,MEN1,POLR2A,RPA1,POLR3G,CACNB1,TAF4,MSH3,EIF2S1,TAF12,ITGB4,POLR1C,KIF1B,GCSH,ANAPC4 |
| 1.953e-06 | -13.15 | regulation of transcription, DNA-templated | biological process | GO:0006355 | 3453 | 532 | 16441 | 2138 |
ASCC1,THOC5,HLTF,CCNL2,ZNF44,SKI,ZNF37A,SREBF2,ZFHX3,IKZF5,ZNF148,FNIP2,KDM5C,HMBOX1,GNL3,EHMT1,NFIA,KRBOX4,RFX2,ZNF197,DDX3X,ZNF266,BRCA2,SUPT4H1,SSU72,RUNX1,ZNF532,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ZNF326,MED24,PRMT5,ZNF518B,MYB,FADS1,ZNF675,GATAD2B,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,ZNF512B,RYR2,SMARCD3,TRIM37,SRA1,ONECUT2,ZNF655,ZNF783,TASP1,GTF2A1,PDLIM1,EHMT2,CDK9,CCDC85B,ZNF160,CNOT6,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,DDR2,SAFB2,HSPA1A,ZKSCAN1,WAC,KMT2D,ZNF480,ATF7IP2,MEF2D,FGFR1,TAF2,KDM4B,ELP2,HIPK2,HOXA3,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,INSIG2,TRAK1,ID2,JMJD6,GAS6,TRIM22,BHLHE40,ZNF691,TADA3,SNW1,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,FGF9,IL6R,ZNF467,FOXC1,UBC,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,BMP4,IGBP1,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,BIRC2,MAP2K3,ECM1,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,TMPO,PTPRK,CHD9,RBCK1,ATF4,AEBP2,ZNF124,PPARG,ZNF414,BAZ2A,HSPA5,MED27,BRCA1,ZNF91,MLLT10,DYRK1B,TCF7L1,INSIG1,TP53BP1,CHD3,E2F4,PER1,TNFRSF1A,DLX2,BEND6,USP15,FOXO1,SMAD7,HES6,ZFP36L1,BARX2,TRIM15,ZIC2,RLF,ARID1B,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,ICE2,CAMKK2,PAXBP1,TLE3,SETD2,UTP15,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,TBPL1,ZNF430,TESC,USP7,ID1,CYLD,ARID2,RBFOX2,RIPK1,ZNF83,ZNF709,SSBP2,PELP1,ZNF121,KDM1A,NRF1,ZBTB21,JAG1,NUP133,DNAJB6,IKBKB,ZFP37,RNF2,PRMT3,KAT8,KDM3B,PCGF3,DDX41,ZNF251,SMAD3,RBBP8,SIX5,ZNF333,KLF4,ZNF436,PUS1,MED20,ZNF18,ZNF589,ZNF507,MAP3K13,RFX1,AGO2,FOXP1,HIST2H2AB,ZNF594,ZNF561,HIST2H3D,SNAPC5,TRNP1,ZNF654,SMARCAD1,FOXN3,ZMYM5,HIST1H4J,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,BCAS3,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,GABPB2,MGA,LPIN1,RNF111,CHD2,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,CUX1,TCEB3,SUPT20H,DENND4A,SAP30BP,GZF1,DOT1L,SPOP,SKIL,TRRAP,CCNT1,ZNF81,HIC2,BMI1,RFXAP,PTPN14,WDR75,IFT57,JUP,EGR1,ZHX3,CENPB,PID1,GTF2IRD1,CHD5,HR,ZNF586,MYC,RREB1,POLA1,ARID1A,NELFA,PLCB1,ZNF850,PHF6,CAT,ZNF425,ASCC3,HIF1A,SPEN,ZBTB12,MED15,PURB,NCOR1,SMYD3,ZFHX2,ZNF254,LIN28B,ZBTB37,FOSL2,IGSF1,RING1,BLOC1S2,TERF2IP,CHD7,ZNF827,KDM2A,PPID,UCHL5,LPIN2,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,SATB2,MED16,PNN,SETD7,ERC1,ZBTB25,SNCA,BAZ1A,VDR,CAMK2D,MSX2,DNTTIP1,SMARCC1,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,SETD6,NCOR2,NOSTRIN,TCF3,ZNF280C,NFX1,MYNN,RCAN1,IKBKAP,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,YBX3,MBTPS2,FAM120B,TSHZ1,SLC40A1,APEX1,KLF6,POLR2A,ZFP62,ZNF155,BRWD3,DDIT3,KAT6A,ZNF76,KMT2E,ATRX,UBN1,ZNF107,SIRT2,BCOR,SNAPC4,SMARCB1,YLPM1,JAZF1,ZEB1,RELB,HCFC2,OGG1,CARM1,TRIM14,ELOF1,ZBTB17,DEAF1,TRIM13,ZNF195,TXLNG,ZNF680,SIRT6,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,UBTF,PAF1,SUFU,GATA6,CC2D1B,MKL2,PQBP1,CLU,ZNF397,ZC3H8,NOCT,DMTF1,EMSY,TAF1,PAX2,DPF2,MED13L,NAMPT,TOX4,RNF141,ELL,ZNF354A,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,ELP3,JMJD1C,ZFP14,WBSCR22,WWC1,PRDM1,EIF2A,APBB3,MYBBP1A,ZFP90,TBL1X,N4BP2L2,ZBTB24,TCF12,ZNF706,ASH1L,DLL4,PBX1,SMARCA4,ZSCAN5A,RRN3,CAMTA2,ZNF142,FHIT,MET,ZNF460,UTP4,MAML3,MOSPD1,PRAME,TFCP2,SFSWAP,GRHL3,POU2F1,ATXN1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,SRFBP1,NFRKB,HEATR1,BRD9,DNAJC2,SUPT6H,CAMK1,H2AFJ,PPHLN1,ATF7IP,MED18,BMP6,PRKCH,HAS3,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,KDM5B,ZNF821,FGF2,TEAD1,KDM5A,PSPC1,ZNF324B,SCMH1,MEN1,PDE2A,ZNF407,ZNF221,HSPA1B,RERE,ZNF708,CUL2,ZRANB2,NFKBIB |
| 1.977e-06 | -13.13 | RAD51 (RAD51 recombinase) | protein interactions | 5888 | 71 | 26 | 16036 | 2270 |
BCCIP,ATRX,TEAD1,FANCD2,VIM,BRCA1,RAD54B,RPA1,SFR1,TERF2IP,ABL1,IRS1,BRCA2,BRE,PALB2,RAD18,CHD3,E2F4,DNAJA3,XRCC2,PDS5B,RAD51B,H2AFX,ATM,MSH4,BRCC3 |
| 2.023e-06 | -13.11 | GCM_CALM1 | MSigDB lists | GCM_CALM1 | 106 | 32 | 17758 | 2279 |
HERC2,SNX27,ANKRD17,MAPK8IP3,KIF5C,RTN4,FOXO3,POGZ,SPIRE1,NUP133,NISCH,VPS52,GSTA4,RAN,KDM3B,SIK3,TSPYL4,TRIM37,UBE2K,TAF9B,RERE,DYNC1H1,FBXO21,EIF4ENIF1,KIDINS220,CLEC16A,MKL2,LARGE,PREPL,XPO6,KIF1B,CORO2B |
| 2.027e-06 | -13.11 | DNA-directed RNA polymerase complex | cellular component | GO:0000428 | 122 | 35 | 17570 | 2233 |
TAF1,POLR1A,MED18,CDC73,TADA3,POLR3D,INTS7,TAF3,GTF2H1,CTR9,INTS12,POLR3B,POLR1B,ZNRD1,POLR1E,CPSF3L,GTF2H3,WDR61,POLA1,POLR2A,POLR3A,TAF9B,POLR3G,PAF1,TAF2,TRRAP,GTF2A1,INTS5,POLR3E,TAF4,TBPL1,INTS9,CRCP,TAF12,POLR1C |
| 2.027e-06 | -13.11 | nuclear DNA-directed RNA polymerase complex | cellular component | GO:0055029 | 122 | 35 | 17570 | 2233 |
TAF1,POLR1A,MED18,CDC73,TADA3,POLR3D,INTS7,TAF3,GTF2H1,CTR9,INTS12,POLR3B,POLR1B,ZNRD1,POLR1E,CPSF3L,GTF2H3,WDR61,POLA1,POLR2A,POLR3A,TAF9B,POLR3G,PAF1,TAF2,TRRAP,GTF2A1,INTS5,POLR3E,TAF4,TBPL1,INTS9,CRCP,TAF12,POLR1C |
| 2.027e-06 | -13.11 | PWP1 (PWP1 homolog, endonuclein) | protein interactions | 11137 | 36 | 17 | 16036 | 2270 |
CUL4A,DDX24,DDX18,SIRT7,HSPA5,PUM3,NOP56,PES1,COPS5,HOXA3,RNF2,SSBP1,COPS6,FBL,DDX10,FTSJ3,TOP1 |
| 2.027e-06 | -13.11 | MPHOSPH10 (M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)) | protein interactions | 10199 | 36 | 17 | 16036 | 2270 |
WDR36,UTP14A,DDX18,GLTSCR2,SIRT7,UTP15,NOL6,CSNK2A1,DKC1,NOP58,NOP56,KRI1,DDX56,NOL10,RNF2,FBL,FTSJ3 |
| 2.110e-06 | -13.07 | purine ribonucleoside binding | molecular function | GO:0032550 | 1795 | 300 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,PDK4,ACTR3,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,IRAK2,DNAH17,HK2,RRAGA,BRSK2,TBCK,DDX10,SUCLG1,PAPD4,MYO7A,RIPK1,SMARCA4,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,RAD54B,TPK1,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,TKFC,ARFIP2,VARS,APRT,CSNK1A1,MFHAS1,GFM2,PIP4K2A,PRKCH,GART,DDX31,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 2.111e-06 | -13.07 | MODULE_18 | MSigDB lists | MODULE_18 | 440 | 91 | 17758 | 2279 |
PTP4A1,TCF12,TRIM16,RIBC2,SLC2A1,CSNK2A1,GYG1,RAC3,MAP2K3,CIAPIN1,CAD,RAP1A,SRSF2,ASNS,SLC39A7,AP1M1,WIZ,SSBP1,KDM5C,POLE3,SERPINH1,PEG10,OGG1,TRIP13,HTRA2,PRPF19,PRAME,RFC4,RFC3,ITPA,VSNL1,GMFB,SEMA3F,CAV1,PITPNB,MCM2,ST3GAL5,CHAF1A,PLIN2,HTR7,SMAD3,HPRT1,RBBP8,PER1,H2AFX,SEMA3C,ANXA2,TPM1,NOLC1,TROVE2,MCM6,AK2,TRIP6,FN1,ZIC2,RCAN1,PHLDA2,IGF2BP3,DDIT4,MTUS1,SLC7A11,MYC,COPS3,SHMT2,MFAP2,CD44,LPCAT1,TOMM34,SERBP1,MTHFD1,FDFT1,MSX1,PXN,APEX1,MYO10,CRIM1,ADSL,ARID1A,GPNMB,CYB5B,ABCF1,SMPDL3B,RPA1,ANXA1,PWP1,SYNCRIP,EHMT2,FAT1,FDPS,NFKBIB,SLC43A1 |
| 2.124e-06 | -13.06 | RRP12 (ribosomal RNA processing 12 homolog) | protein interactions | 23223 | 51 | 21 | 16036 | 2270 |
NIFK,CUL7,DDX24,GLTSCR2,SKIV2L2,SIRT7,RSL1D1,CSNK2A1,EIF2A,RBM19,EIF5B,RBM28,NOP58,TSR1,DDX56,COPS5,RNF2,NOC3L,COPS6,PRMT5,BMI1 |
| 2.140e-06 | -13.05 | ZF_PHD_2 | prosite domains | PS50016 | 74 | 25 | 11866 | 1504 |
DPF3,PHF3,KMT2D,KDM5B,KMT2E,BAZ2A,KDM5A,DPF2,NFX1,RSF1,KMT2C,CHD5,TRIM66,MLLT10,BAZ1A,NSD1,BAZ2B,KDM2A,TAF3,CHD3,INTS12,KDM5C,FBXL19,KMT2A,KAT6A |
| 2.171e-06 | -13.04 | EED (embryonic ectoderm development) | protein interactions | 8726 | 457 | 101 | 16036 | 2270 |
USP7,CUL4A,ACTG1,DDX18,NAT10,MYH9,RSL1D1,SMARCA4,BCOR,SAFB2,NUP160,HNRNPA3,MGA,KDM1A,RING1,NOP56,PHC2,SRSF2,RPS16,BCAS2,KDM2A,NUP133,GLYR1,PDS5B,WIZ,CHD2,RNF2,RAN,SRRM2,ZMYM2,FTSJ3,SF3A1,TMPO,PRPF19,SNU13,AEBP2,BAZ2A,SKIV2L2,NPM3,GNL3,RAB7A,HSPA5,EHMT1,NOL6,BRCA1,DKC1,SON,DSP,RBM28,PUM3,DDX3X,RANBP2,TRRAP,SMARCC1,TP53BP1,HNRNPR,ADNP,LUC7L3,CEBPZ,HEATR1,NOLC1,PDCD11,BMI1,EP400,NIFK,JUP,UTP14A,SUPT6H,SF3A3,VARS,POGZ,DSG2,ZNF326,ANXA5,GTF3C3,EXOSC4,FBL,HNRNPM,TOP1,CLK2,NOM1,GATAD2B,STAG1,PSPC1,KDM5A,TRA2A,KCNMA1,ARID1A,MEN1,NOP58,ABCF1,POLR2A,DDX50,NOL10,MYBBP1A,SYNCRIP,EHMT2,HNRNPH3,SPEN,SRP14,SMYD3 |
| 2.172e-06 | -13.04 | DANG_BOUND_BY_MYC | MSigDB lists | DANG_BOUND_BY_MYC | 1066 | 188 | 17758 | 2279 |
SRM,PTP4A1,POLB,EIF3C,ACTG1,PRKCSH,PRKAB2,MRPL10,NAT10,AMPD3,RPS16,SRSF2,SREBF2,ATP5G2,SLC39A7,ANAPC10,VPS52,POLE3,ZNF85,KDM5C,NDUFA6,FXN,HCFC2,ZNRD1,SRRM2,CDK6,SPAG6,METTL1,GDAP1,NRAS,ATF4,ABCC4,NR6A1,HARS,GNL3,CDK4,AP4B1,TCEB3,MINA,KIF15,ATG12,PSMG1,MCL1,ODC1,MGST1,CLNS1A,PYCR1,DDX3X,SLC7A1,PER1,ARL6IP5,SYNGR2,PQBP1,DMTF1,DCTN3,SARS,UBXN1,SMAD7,ZFP36L1,CLINT1,TIMM10,RNF141,ELL,MLX,USPL1,COPS3,MCM5,MYC,GMDS,PRMT5,CNOT4,PPA1,MTHFD1,NAA38,ZNF234,CRADD,LAMC1,SIGMAR1,PPAT,TLE3,PSMA1,SUPT5H,HERPUD1,PWP1,MGAT2,TRAP1,HIF1A,SRP68,RRAGA,HMBS,PTP4A2,CNDP2,DDX10,BCCIP,TCF12,MAP2K5,SUCLG1,BIRC6,DDX18,RPS29,UROD,ACTR3,OLA1,NDUFB5,LAGE3,EEA1,PAIP2,NDUFB3,CAD,RPP30,PPID,VGF,CLCN6,ZNF142,ETF1,MET,AHCYL1,CASP8AP2,SAP30,WDR36,PMS1,MPP6,DDX41,PARP2,PCMT1,POU2F1,KIAA1586,GNL1,DKC1,SERP1,MAT2A,SMAD3,EXO1,RBBP8,CDC16,KPNA3,CEBPZ,H2AFX,FTSJ1,CBWD1,SLC25A11,RPS6KB1,USP11,SCAMP3,ARFIP2,ID2,TGFB2,RPS6KA5,MBNL1,POLR3D,NPRL2,CWC27,CFDP1,DCTN4,POLR1B,TOP1,ULBP1,PFKFB4,FGF9,IL11RA,AP4S1,APEX1,SMARCAD1,KDM5A,TMEM126A,LDHA,MARS,MEN1,TMEM187,UBE2K,SYMPK,POLR3A,POLR3G,YIF1A,CACNB1,ALG5,ACOX1,HERC1,EIF2S1,ATM,NCBP2,BMP4,PSAP,NFKBIB,IGBP1,ZAK,SLC43A1,NIT1 |
| 2.296e-06 | -12.98 | HIV Life Cycle | REACTOME pathways | R-HSA-162587 | 140 | 40 | 8202 | 1117 |
CHMP2A,TAF1,GTF2H2C,VTA1,AK6,NUP43,NUP160,POM121,ELL,NUP133,TAF3,BANF1,GTF2H1,RAN,SEH1L,GTF2H3,VPS37A,RNMT,TCEB3,LIG4,RANGAP1,SUPT5H,NELFA,NUP214,UBC,POLR2A,TAF9B,TAF2,RANBP2,KPNA1,SUPT4H1,GTF2A1,CCNT1,CDK9,VPS37B,TAF4,NCBP2,TAF12,XRCC4,CHMP4C |
| 2.324e-06 | -12.97 | GSE17721_LPS_VS_CPG_1H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_1H_BMDM_UP | 190 | 48 | 17758 | 2279 |
MYCBP2,VTA1,RARS2,MRPL10,VPS45,CSPP1,APRT,LIAS,LCLAT1,PRKCE,MLX,RPS16,ENTPD5,MCM5,SLC39A7,SOCS6,METTL8,GPATCH1,C16orf58,SELT,NT5C,PRPF19,ACSL5,MPP6,GARS,PTBP2,CDK4,PSPC1,PPP1R21,MANBAL,BMS1,EIF5B,EVI5,SERP1,C1orf174,PES1,ELP2,SRRD,TRAP1,SNAP23,RNF138,TRMT2A,TMEM101,COPS6,BRWD3,GCSH,BAG1,TMEM33 |
| 2.383e-06 | -12.95 | SNU13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)) | protein interactions | 4809 | 154 | 44 | 16036 | 2270 |
SART1,NIFK,FN1,UTP14A,DDX18,PRPF31,RSL1D1,PABPC4,NOP56,METTL16,SNW1,DDX56,BCAS2,PTRF,NOP16,ZNF326,RNF2,CORO1A,FBL,PABPC1,HNRNPM,METTL1,SNU13,DDX24,TRA2A,GNL3,ZC3H18,WDR18,IMPDH2,EIF2A,DKC1,SON,NOP58,TARS,PES1,SYNCRIP,KDM4B,HNRNPR,PRPF4,KIAA0196,NOLC1,BMI1,SRP14,RFXAP |
| 2.430e-06 | -12.93 | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | MSigDB lists | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | 417 | 87 | 17758 | 2279 |
ZNF254,BCCIP,TNFRSF21,LPCAT2,PPARGC1B,FANCD2,TMEM109,VTI1A,ZNF107,TUBE1,ENAH,NECAP1,CSPP1,SLC29A1,PABPC4,DENR,NOP56,XRCC2,BCAP29,RAN,ZNF85,MET,C6orf89,TRIP13,PRPF19,PHLDB2,WDR36,RFC3,MIOS,KLHL23,CDK4,KIF15,MRRF,METTL15,HDAC8,FOXRED1,ZNF91,DLST,SLC30A3,ARL13B,RIOK1,MDN1,KLHDC4,FIP1L1,RFXAP,MAPT,FGFBP3,SHQ1,VPS45,PHGDH,PARN,BMP6,NEDD4,POM121,NAV1,EIF2S2,SACS,SLC7A11,TNPO3,UPF2,COPS7B,ANP32B,LPCAT1,POLR1E,MYB,VOPP1,BDNF,STAG1,GINS3,TRA2A,PSMC3IP,HAUS6,SETD2,XPO5,LDHA,ARHGAP32,ARID1A,ABCF1,TCF7L2,POP1,ATAD5,NOL10,SLC25A19,NCOR1,PTP4A2,NFKBIB,XPO6 |
| 2.443e-06 | -12.92 | purine nucleoside binding | molecular function | GO:0001883 | 1798 | 300 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,KIF16B,PEX1,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,SARS,TTN,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,HK2,RRAGA,BRSK2,TBCK,DDX10,SUCLG1,PAPD4,MYO7A,RIPK1,SMARCA4,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,TPK1,RAD54B,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,TKFC,ARFIP2,VARS,APRT,CSNK1A1,MFHAS1,GFM2,PIP4K2A,PRKCH,GART,DDX31,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 2.646e-06 | -12.84 | USP7 (ubiquitin specific peptidase 7 (herpes virus-associated)) | protein interactions | 7874 | 251 | 63 | 16036 | 2270 |
USP7,MCM6,CUL4A,XPC,WDR74,ZCCHC8,SIRT7,MYH9,MYNN,HLTF,TRIM22,BCOR,PHGDH,RADIL,FOXO3,BIRC2,ZNF594,RING1,ABL1,BRE,ACD,YLPM1,MCM5,TANK,ZEB1,RNF2,HTRA2,TMPO,CDC37,RPS6KB2,DBN1,PCGF3,PHLDB2,RBCK1,PPARG,SIRT6,SMARCAD1,ATXN1,BRCA1,PITPNB,UBC,VPS53,HERPUD1,UBE2E1,RPA1,SMAD3,DYNC1H1,TRRAP,TRAP1,SRP68,DNAJA3,COPS5,SVIL,TRAF3,FKBP5,RBPJ,COPS6,BRCC3,USP11,XRCC4,BMI1,MTCH1,USP15 |
| 2.676e-06 | -12.83 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 467 | 95 | 17758 | 2279 |
SPRED2,ADAM19,ASH1L,FAM208B,ABCA3,NF1,ATP6V1A,NPAS2,CNTNAP3,PDK4,PRR4,ARSJ,LPIN1,METTL16,DST,PMAIP1,PPFIBP1,SETD5,GLYR1,WAC,MMP14,MET,CDK6,PRKACB,MOSPD1,MAML3,PHLDB2,ANTXR2,TUBA1A,ABCC4,SSFA2,ENHO,NR6A1,ZNF480,MCL1,ENC1,STK10,DCBLD2,CXADR,GLS,GNG2,DDX3X,SLC7A1,RANBP2,CAMK2D,DUS3L,SMARCC1,HEATR1,BRCC3,TMEM158,ZMAT3,SMG1,KLHL24,HMGA2,TNIK,FN1,SUPT6H,TRIO,PDE4B,SMG7,AKT1S1,TGFBR2,MBNL1,SPIRE1,MAN1A1,IGF2BP3,IQGAP2,NAMPT,SLC7A11,NDRG4,CD44,ERRFI1,FMNL2,NAV3,TOP1,ARNTL2,GPHN,TEAD1,KCNMA1,JMJD1C,PTPN12,USP10,PRDM1,OASL,KLF6,MBNL2,FOXC1,EPRS,STX1A,SNAP23,SLC16A1,CDKAL1,MMP16,STK4,KAT6A |
| 2.773e-06 | -12.80 | JAIN_NFKB_SIGNALING | MSigDB lists | JAIN_NFKB_SIGNALING | 74 | 25 | 17758 | 2279 |
ZNF195,ITPA,POLA1,LIG4,SMG7,PSMG1,APRT,SLC29A1,XPO7,SYMPK,HSPA1A,HDDC2,CLNS1A,HSPA1B,SLC23A2,ASCC3,DECR1,TPD52L2,ARMC6,MYC,ORC5,HK2,PREPL,FBL,STK4 |
| 2.773e-06 | -12.80 | transcription cofactor activity | molecular function | GO:0003712 | 537 | 108 | 16491 | 2164 |
TRERF1,KMT2E,RBFOX2,PPARGC1B,SMARCA4,BCOR,BIRC2,LPIN1,KDM1A,SKI,SMARCB1,SRSF2,JAZF1,LPIN2,RELB,ZEB1,ZNF85,RAN,HCFC2,TRIP13,CASP8AP2,CARM1,SAP30,MAML3,AEBP2,SIRT6,PPARG,MED27,MED16,SUPT20H,BRCA1,SOX4,TAF9B,BATF3,DYRK1B,SKIL,MSX2,RBBP8,TRRAP,SMARCC1,SUFU,TP53BP1,COPS5,HIPK2,MKL2,PQBP1,PUS1,FUS,MED20,BEND6,RFXAP,PTPN14,WDR75,NCOR2,JUP,TAF1,ZHX3,TCF3,HES6,MED13L,MED18,ATF7IP,TRIM22,BHLHE40,ARID1B,SFR1,TADA3,SNW1,SUB1,HR,BUD31,MED24,YBX3,ZNF710,PRMT5,NRIP1,APEX1,KDM5B,FGF2,PRDM16,KDM5A,ARID5B,PSMC3IP,SMARCD3,WWC1,ARID1A,SRA1,NR2F1,RERE,ZNF783,TRIB3,NSD1,SRCAP,MYBBP1A,GTF2A1,PDLIM1,SPEN,MED15,TAF4,TBPL1,NCOR1,TBL1X,TAF12,NFKBIB,NR2F2,DDIT3,N4BP2L2,KAT6A |
| 2.790e-06 | -12.79 | negative regulation of gene expression | biological process | GO:0010629 | 1508 | 255 | 16441 | 2138 |
ATRX,PPARGC1B,POLR1A,BCOR,CHAC1,SIRT2,NUP160,BIRC2,SKI,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,RAN,KDM5C,SLC35C2,HCFC2,ZNRD1,TRIM14,SEH1L,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,ATF4,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,TSN,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SAP30BP,SPOP,DOT1L,TAF9B,GZF1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,SUPT4H1,EIF4ENIF1,SUFU,GATA6,CCNT1,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,NOCT,BMI1,TNRC6A,MEF2C,DROSHA,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,BARX2,ZIC2,RSF1,CDC73,IGF2BP3,RNF40,MLX,HR,MBD2,MYC,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,IGF2BP1,NRIP1,POLR1E,PABPC1,TERF2,MYB,ZNF675,GATAD2B,GTF2H3,PAXBP1,RREB1,PRDM16,XPO5,ARID5B,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,EPRS,MYBBP1A,SYNCRIP,EHMT2,CDK9,SPEN,IRAK2,CCDC85B,PURB,PTRH2,ZFP90,CNOT6,TBL1X,NCOR1,AGO3,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,MAP2K5,CYLD,UPK3B,LIN28B,RBFOX2,SMARCA4,PBX1,NUP43,RING1,KDM1A,PAIP2,ZBTB21,ERI1,PPID,NUP133,DNAJB6,RNF2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,PTBP2,SFSWAP,ATXN1,POU2F1,SATB2,ENC1,NUP214,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RANBP2,RBBP8,IKZF4,ELP2,ADNP,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,EIF2B3,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,SHQ1,TCF3,AGO2,H2AFJ,NFX1,ID2,IGF2BP2,ATF7IP,GAS6,BHLHE40,RNASEH2B,NOL3,RPS6KA5,FOXP1,GIGYF2,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,POM121,SNW1,ANXA7,SUV39H2,TAF3,STC2,HIST2H3D,CELF1,POLR1B,YBX3,SAMD4A,DMRT1,SOX6,FGF9,MSX1,KDM5B,PSPC1,FOXN3,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,POLR2A,RERE,MKX,DKK1,TRIB3,NSD1,IREB2,TBX3,SET,GLG1,EIF2S1,NCBP2,RBPJ,BMP4,POLR1C,NR2F2,IGBP1,DDIT3,KAT6A |
| 2.873e-06 | -12.76 | tRNA binding | molecular function | GO:0000049 | 43 | 18 | 16491 | 2164 |
CARS,CTU2,METTL1,XPO5,AARS2,FARS2,MARS,EIF2A,AARS,YARS2,FARSA,RARS,EEFSEC,IFIT5,TRMU,ALKBH8,TRMT10A,YARS |
| 2.928e-06 | -12.74 | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDM_UP | 186 | 47 | 17758 | 2279 |
WDR75,SARS,C9orf78,ID1,EGR1,ATRX,PRKCSH,SIRT7,UBXN1,PBX1,ZFP36L1,VARS,PITPNM1,IQGAP2,COMMD9,FAM50A,COPS4,PHF5A,SURF2,TBC1D22A,AP1M1,POLE3,CPSF3,TSPAN14,LPCAT1,CSGALNACT2,TIMM50,SF3A1,WDR61,SLC38A1,MTIF2,LDHA,PSMG1,GALK2,GPNMB,SLC50A1,C1orf174,DHX57,CLNS1A,TPK1,VPS13C,BRCA2,COQ9,PER1,DUSP19,PREPL,ZMAT3 |
| 2.928e-06 | -12.74 | GSE27786_BCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_BCELL_VS_MONO_MAC_UP | 186 | 47 | 17758 | 2279 |
MYCBP2,ESCO1,RWDD1,C17orf80,ATRX,KHDRBS1,SF3A3,NOP56,ABL2,RPS16,NDUFV1,UBE3A,UBR1,ATP5G2,TRIAP1,LPIN2,RNF2,ZNRD1,NAA35,RPL22L1,HSD17B12,TSHZ1,NARS2,ZNF124,DDX24,KDM5A,SETD2,ZNF512B,GMFB,MARS,CAMSAP2,RAB10,POLR2A,ARIH2,ATP5D,UBTF,POP1,CAT,ZZEF1,ARNTL,TRMT2A,IFT140,NFRKB,XPO6,GCSH,IPO4,SMG1 |
| 3.091e-06 | -12.69 | MRTO4 (MRT4 homolog, ribosome maturation factor) | protein interactions | 51154 | 52 | 21 | 16036 | 2270 |
ADARB1,SNU13,NIFK,FN1,DDX24,SIRT7,XPO5,SUPT5H,PUM3,TERF2IP,PES1,DDX56,ZNF622,NOL10,EIF2S2,CUL2,RNF2,FBL,BMI1,FTSJ3,NMD3 |
| 3.185e-06 | -12.66 | GSE360_CTRL_VS_L_MAJOR_MAC_UP | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_MAC_UP | 192 | 48 | 17758 | 2279 |
PLRG1,UROD,SMARCA4,POP5,SLC25A44,FAM13A,RAC3,POM121,NDUFS7,ABL1,TTC1,NDUFV1,SREBF2,NUP133,BANF1,PDS5B,ARHGAP1,SERPINH1,ATP6V0D1,PRKACB,SNAPC5,ZNF629,RBCK1,TSTA3,NARS,PCCA,PCMT1,RAP1GDS1,USP10,MARS,GALK2,IMPDH2,MAK16,CHAF1A,SH3GL1,SPOP,ZBTB25,SMAD3,AHNAK,SMARCC1,PEMT,SET,CFD,DNAH17,GLG1,SLC4A7,DHCR7,SLC43A1 |
| 3.291e-06 | -12.62 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 697 | 131 | 17758 | 2279 |
ZNF292,CDCP1,CUL4A,ACTG1,ATRX,CSPP1,IKBIP,SLC6A8,NEK6,NCKIPSD,FUT11,ZMYM2,LONP1,TRIP13,TBC1D8,SLC3A2,SLC38A1,ATG9A,ARRDC3,NFIA,AKAP12,SUMO3,MTHFD1L,SH3GL1,INSIG1,VPS13D,SGSM2,PPP3CC,RUNX1,TNFRSF10D,TPM1,PTPN14,PGPEP1,PAX2,TRIO,NHS,SMAD7,MAPK8IP3,SLC1A1,SPIRE1,DDIT4,MTUS1,CHN1,KIAA1958,KIAA1671,ASAP1,MCM5,MBD2,MYC,GLTP,ALDH18A1,LPCAT1,ZNF629,ADARB1,PEA15,IFNGR2,ANGPTL4,ZNF655,TSR1,PMEPA1,FSCN1,HK2,RRAGA,SLC16A1,PTP4A2,N4BP2L2,MPI,SPRED2,FAM207A,SPATA2L,SLC2A1,PIGH,MYH9,RNF24,TUBB6,SEMA6A,SLC39A1,PHC2,KCTD11,KDM2A,DNAJB6,WAC,SLC38A2,MGLL,TMEM120B,PERP,SAP30,DDX41,PDK1,LGALS1,VIM,MEF2D,MARCH6,STK10,HSD3B7,USP36,PLIN2,SLC39A14,ARNTL,FTSJ1,PAM,TRAF3,YEATS2,BCKDK,INSIG2,TCF3,ARFIP2,JMJD6,BHLHE40,NOL3,NEDD4,PTRF,STC2,CD44,MICAL3,MARCH9,FBXO17,KDM5B,FOXN3,KCNMA1,LDHA,PACS1,KLF6,OXSR1,TRIB3,GADD45A,DSC2,ARID3B,RBPJ,MTMR1,ARHGAP27 |
| 3.298e-06 | -12.62 | RCGCANGCGY_V$NRF1_Q6 | MSigDB lists | RCGCANGCGY_V$NRF1_Q6 | 860 | 156 | 17758 | 2279 |
NF1,SBF2,GIT2,GABPB2,SMARCB1,RPS16,SRSF2,ATP5G2,SLC39A7,AP1M1,RNF111,KDM5C,FUT11,ZMYM2,SRRM2,FTSJ3,SEH1L,ZNF646,ZBTB17,SLC3A2,SIRT6,GDPD1,ARRDC3,VSNL1,WDHD1,SON,SLC9A5,TMEM206,SPOP,BSN,DDX3X,SUFU,MKL2,SOCS4,ZC3H8,TSEN2,RFXAP,BANP,EPM2AIP1,STX8,DPF2,LAMTOR3,SSR4,RNF40,EIF2S2,MLX,INTS7,GEMIN4,COQ3,ZCCHC7,CNOT4,ATP6V0D1,PABPC1,CPSF3L,EXOSC2,STAG1,ALG6,POLA1,XPO5,TYW1,IDH3G,RDH10,SMARCD3,EIF2A,METTL22,TRIM37,VPS13C,APBB3,KPNA1,PALB2,GTF2A1,INTS5,SDCCAG8,PPP1R12B,PRKAR2A,NR2C2AP,BCCIP,CHMP2A,NDUFA5,DNM3,PCNT,PAPD4,RWDD1,RPS29,TBCCD1,FAM122B,RNF24,SBDS,KDM1A,BLOC1S2,PAIP2,JAG1,ARMC6,KDM2A,SHC1,WAC,C15orf40,NBEA,MSH4,CPSF3,NAA35,IPO11,POU2F1,AKAP13,SLC35D1,SERP1,RAB10,ATP5D,ZFAND3,RBBP8,YIPF2,SIX5,DNAJA3,EIF2B3,MAPT,BAG1,SSH2,ESCO1,MINK1,SCAMP3,LETMD1,ATF7IP,MLH1,AKT1S1,PTPN2,SNW1,NPRL2,GART,NOP16,LRP2BP,SEC24C,DCTN4,SHMT2,UPF2,SELT,ERRFI1,TOP1,FAM98A,PSPC1,MARS,LENG8,EXOG,EIF5B,UBE2K,SYMPK,POLR2A,CCDC150,MRPL36,ALG5,GPC2,WDR35,SET,ATM,EIF2S1,DDIT3,KDM4C |
| 3.338e-06 | -12.61 | - | gene3d domains | 2.130.10.10 | 327 | 76 | 9988 | 1398 |
DMXL2,GNB3,BIRC6,PAFAH1B1,WDR74,WDR13,PLRG1,PPP2R2A,NUP43,CORO6,NBEAL1,DENND3,NLE1,SEMA6A,PLXNB1,AMBRA1,NUP133,NBEA,PAK1IP1,CORO1A,MET,UTP4,LYST,SEH1L,PRPF19,WDR36,FBXW4,MIOS,ARHGEF10,WDHD1,SEMA3F,MED16,NUP214,GEMIN5,ELP2,WDR5B,WDR73,TECPR2,TSSC1,WDR7,IFT140,PRPF4,SEMA3C,WDR66,DCAF5,WDR75,PIK3R4,MAPK8IP3,WDR26,WDR37,SEMA3E,PEX7,WDR27,WDR60,SEMA3D,WDR61,WDFY3,TLE3,WDR18,UTP15,WDR25,EIF2A,SEC31A,PWP1,NOL10,SPAG9,PALB2,WDR35,HERC1,BCAS3,APAF1,TBL1X,WDR33,BRWD3,ANAPC4,CORO2B |
| 3.343e-06 | -12.61 | DAZARD_UV_RESPONSE_CLUSTER_G6 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G6 | 144 | 39 | 17758 | 2279 |
HMGA2,INSIG2,PHF3,FOXO1,NPAS2,PAFAH1B1,SSBP2,FOXO3,UBR5,BIRC2,MTUS1,IGF2BP3,DOPEY1,ABL1,RABGAP1L,MBD2,CNOT4,LPCAT1,TBC1D8,VPS13B,NAV3,PMS1,CHD9,WWC1,FERMT2,PTK2,MARCH6,SPOP,SMAD3,BAZ1A,SLC7A1,IRS1,POLE2,LSM14A,FAT1,RBPJ,FNBP1L,SGSM3,KAT6A |
| 3.364e-06 | -12.60 | ribonucleoprotein complex | cellular component | GO:0030529 | 691 | 129 | 17570 | 2233 |
EIF3C,DCP1B,TFIP11,MRPL10,PLRG1,NAT10,PPIL1,SCAF8,HNRNPLL,PABPC4,EDC3,MRPS30,RPS16,SRSF2,PHF5A,NSRP1,ZNHIT6,GPATCH1,SRRM2,FTSJ3,SF3A1,SNU13,SKIV2L2,NOL6,BRCA1,RBM28,YTHDF2,DDX3X,ZNF622,EIF4ENIF1,LSM14A,EEFSEC,LUC7L3,PQBP1,PRPF4,NOCT,TNRC6A,PRPF38B,ZCCHC8,PRPF31,MEX3A,PRPF39,PDCD7,ATXN2,ZNF326,BUD31,IGF2BP1,GEMIN4,MRPL21,PABPC1,MSI2,NAA38,DDX28,UTP15,PSMA1,MEX3B,SRA1,ABCF1,POP1,PRPF40B,EPRS,SYNCRIP,RPL28,SRP68,SRP14,AGO3,SART1,BTBD2,RPS29,POP5,ZMAT2,HNRNPA3,DHX35,NOP56,RPP30,MPHOSPH10,BCAS2,NVL,ERI1,RPS6KL1,WAC,MRPS27,CPSF3,PRMT3,LSM10,NAA35,PRPF19,WDR36,DDX41,PTBP2,TUBA1A,EIF3J,PNN,DKC1,SERP1,EIF3H,SNCA,PES1,HNRNPR,ARNTL,SRFBP1,FUS,HEATR1,PDCD11,TROVE2,PPIL3,MAPT,UTP14A,AGO2,SF3A3,MBNL1,MRPS11,SNW1,CTNNBL1,CWC27,CELF1,FBL,LARP4B,YBX3,RPL22L1,HNRNPM,TOP1,DIS3L2,APEX1,MRPS10,NOP58,MRPL36,HNRNPH3,EIF2S1 |
| 3.432e-06 | -12.58 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_UP | 187 | 47 | 17758 | 2279 |
NCOR2,PRPF38B,PRPF31,URB2,MRI1,UROD,SF3A3,PCSK7,SLC25A12,WDR37,TUBB6,POP5,PCYOX1L,GATC,PSMG4,CWC27,MYC,GPATCH1,CTR9,POLR1E,IPO11,HNRNPM,TIMM50,DDX28,RFC3,FAM172A,NARS,LIMA1,ITPA,SMARCAD1,ANKMY2,HAUS6,SCFD2,GMFB,KIAA0586,PTK2,TRIM37,USP46,LSG1,PEX1,ORC5,TSSC1,BIVM,SENP3,UMPS,HEATR1,PRKAR2A |
| 3.449e-06 | -12.58 | bone | COSMIC cancer mutations | bone | 8539 | 1195 | 17775 | 2278 |
ARHGAP26,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,SBF2,CCNL2,HMOX2,SLC6A8,LPAR3,CIAPIN1,ZNF37A,PDZD2,MMP7,ZFHX3,THAP4,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,NRAS,KLHL23,LIMA1,EHMT1,AP4B1,KIF15,C11orf80,WDHD1,ABCC2,ZNF197,PYCR1,SLC7A1,AHNAK,LRRC40,RUNX1,SLC25A26,ZNF532,TMEM63C,FAM189B,TRIO,PARN,CDC73,PITPNM1,RSPRY1,RBM20,UBE3A,CNST,DHX37,MED24,WDR60,GEMIN4,MRPL21,PABPC1,SAMD3,ANGPT2,KLRD1,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,USP10,MAP7D1,ST6GALNAC3,SRA1,IRS1,DYNC1H1,TSR1,NME7,EHMT2,TRAP1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,RAB11FIP4,C16orf45,FAM122B,ISG20L2,LCLAT1,ZMAT2,RPGRIP1L,ESAM,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,INTS12,MSH4,ZC3H3,LYST,PMS1,KMT2D,SLCO6A1,PCNXL2,MEF2D,KCNH3,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,ARHGAP21,ELP2,KDM4B,ASTN2,ARL13B,POLR3E,RPS6KB1,CENPBD1,METTL2B,CEP170,MAPT,MORC2,HMGA2,XRRA1,ATG2B,POLR3D,TAF3,UNC13A,ACOT11,LTN1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,RPL22L1,SPTAN1,DDX24,ZC4H2,CCDC150,ANXA1,NSD1,SRCAP,HERC1,ACOX1,AEN,BMP4,SORCS2,CUL7,SLC25A21,AMPD3,ECM1,NCKIPSD,ANKRD11,HKR1,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,ATF4,MIOS,ANK2,MARCKSL1,LAMA2,KCNH2,CRYBG3,BSN,TCF7L1,LSS,INSIG1,CHD3,C3orf35,PPP3CC,TSEN2,MAGI1,BEND6,CTU2,FOXO1,CLK1,ITFG1,PRSS3,MAPK8IP3,ARID1B,MLX,CEP290,VPS72,NDRG4,VAPB,CTR9,PNPLA3,CWF19L2,SNX29,USP49,SETD2,HAUS6,OBSCN,CYB5B,TBC1D2,PRPF40B,GRIK4,TTC38,CASS4,SIL1,PTP4A2,GGT7,DDX10,USP7,MPI,SART1,OLFM2,ARID2,NDUFAF2,OSBPL9,NTSR1,RPS29,RIPK1,SSBP2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PAG1,DDX60L,PLXNB1,ANKRD13A,ZNF608,NRF1,JAG1,NUP133,GRIN2C,ANKRD24,CCDC40,MYH15,BCAP29,IPO11,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,CA5B,TJAP1,EXO1,IFT81,LMBR1L,KLF4,INTS9,MED20,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,RFX1,VARS,RBM19,HIST2H2AB,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,LRRIQ1,SMARCAD1,ABCF2,TOP3A,FERMT2,ARHGEF12,PALLD,SMPDL3B,POLR3A,DKK1,CDH24,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,RBM26,XPO6,KIF1B,C6orf223,ZNF292,LUZP1,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,ZNF646,OSBP2,ZDHHC14,SON,DENND4A,DDX60,TMEM206,PLCXD2,GZF1,DOT1L,OSBPL1A,TRRAP,LSM14A,SH3RF1,LUC7L3,HSPBAP1,HIC2,XPNPEP1,NRP1,BMI1,NMD3,PRPF38B,C9orf78,LARS2,PRPF31,DLGAP4,NDUFS7,MTUS1,FAM192A,TECTA,SLC7A11,USPL1,SCAF1,MYC,PIGG,RTFDC1,FDFT1,RREB1,PRIM2,RAPGEF4,RAP1GAP2,RDH10,ARID1A,EHBP1,ANGPTL4,SLC26A11,MTR,ATP9B,CAT,ASCC3,HIF1A,VCAN,SPEN,MED15,ZCCHC6,SQLE,DPEP1,NCOR1,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,TMEM104,PLEK2,POP5,PTPRG,CORO6,IGSF1,BLOC1S2,NUBPL,DECR1,ARMC6,LPIN2,SOCS6,MRPS27,SHF,TTC3,CDK12,GON4L,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,ZBTB25,BAZ1A,MSX2,SMARCC1,WDR5B,MBTD1,FTSJ1,LARGE,IFT140,CBWD1,TRAF3,TBXA2R,SETD6,MID1,SSH2,NOSTRIN,BRAF,OPA1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,CLK2,TMC7,TTLL5,PXN,APEX1,ZFYVE1,PACS1,BMS1,C9orf153,SLC23A2,RETSAT,ZNF155,DDX50,COQ9,ORC5,ATM,SVIL,APAF1,IPO4,IMMP2L,PIGM,ZNF76,LETM1,ATRX,RARS2,PCYOX1L,DST,MYH3,KIAA0922,HCFC2,YARS,DTNB,TNK2,DEAF1,SESN2,SKAP2,ZNF195,ARRDC3,TFPI,VWCE,KSR2,MTHFD1L,SGK2,KMT2C,ST3GAL5,CCDC3,CC2D1B,CRCP,CSMD3,EME1,DCAF5,DCTN3,RHOBTB1,VTA1,PCSK7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,PRF1,ZCCHC7,ATP6V0D1,AKAP11,HSD17B14,MTHFD1,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,ELP3,ZBED4,JMJD1C,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,EXOC6,MGAT2,SYCP2L,APBB3,BICD1,KIAA0355,FSCN1,FAT1,KIAA0754,FDPS,TMEM117,CDKAL1,TBL1X,PFDN2,FNBP1L,TBCK,TCF12,DMXL2,FEZ2,PSTPIP2,TMEM183A,TNXB,SMARCA4,TBCCD1,COBLL1,SPATS2,DHX35,RIOK2,ZC3H13,RAET1E,PPFIBP1,SNTG2,FHIT,ITGAX,VCL,C6orf89,MAML3,RTN4RL2,GRHL3,METTL2A,ATXN1,POU2F1,MRRF,METTL15,EDEM2,UBR4,S100A16,ARMC4,ALAD,KPNA3,IKZF4,CEBPZ,TMEM101,NFRKB,BRD9,SMG1,TMEM33,TMCC1,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,WDR26,ATF7IP,SEMA3E,FAM49A,MFHAS1,BMP6,SEC24C,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,KDM6B,SLC6A16,DNMBP,ZNF821,CRIM1,PSPC1,SCMH1,EIF5B,NAALADL2,CTIF,WDR35,AGTPBP1,VPS37B,GNB3,CACNA1H,CSPP1,CHAC1,SYNJ1,AMBRA1,NOS1AP,PCDH7,TOM1L1,SREBF2,RABGAP1L,PDS5B,ZNF148,AVEN,GNL3,PTPRM,RFX2,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,ZNF266,SUPT4H1,BRCA2,MEF2C,HERC2,CARS,EP400,CLDN15,KHDRBS1,NHS,RSF1,CLINT1,YARS2,SLC39A11,ABCA7,C6orf48,DDX56,INTS7,MCM5,CACNB2,ANP32B,PRMT5,MAP3K12,COQ3,FMNL2,TOMM34,HMGCR,BDNF,TIMM8B,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,IMPDH2,EVI5,ABCF1,NCDN,VPS13C,LRP1B,TASP1,GTF2A1,LEMD3,ZNF160,WDR33,COG5,ZNF516,DNM3,ABCA3,TRERF1,DDX18,ATP6V1A,MYH9,NECAP1,SAFB2,EEA1,ABCA12,FMNL1,ATRIP,GSTA4,CEP63,MTHFD2L,KRT7,ARHGEF10,ADAM32,FKBP3,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,CDC16,IQCH,WDR7,PAM,FUS,ANKS1A,LAMA5,YEATS2,LRCH1,ZNF786,XPC,TRAK1,SF3A3,WDR37,JMJD6,TGFB2,RSRC1,POM121,KRI1,TADA3,TMSB10,PVRL3,HNRNPM,SOX6,ULBP1,DIS3L2,ERICH1,ARHGAP39,MRPS10,R3HDM2,PDE3B,CASC1,RARS,TOE1,TRIB3,ETFDH,BAZ2B,PXDN,ARID3B,PTPN4,SLC25A19,PSAP,NUDT22,DOCK6,KDM4C,ANAPC4,CORO2B,POLR1A,TFIP11,PPARGC1B,CSNK2A1,RNF43,TMEM132A,TTI1,SEC16A,ARHGAP18,DHX33,ETV1,CDC37,TMPO,FLNC,CHD9,GCNT2,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,COL4A3BP,NOL6,BRCA1,ZNF91,FLVCR1,MGST1,KIF16B,PEX1,GLS,ZNF622,TP53BP1,EEFSEC,TECPR2,CCDC146,TNFRSF1A,SGSM2,RNF214,XYLB,SEPHS2,OXNAD1,AOC3,MCM6,ITPRIP,TRIM15,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,TIMELESS,SYNJ2,ALDH18A1,GMDS,CAMKK2,LAMC1,CRADD,WDR25,ZNFX1,SUPT5H,TRAPPC6B,VAC14,NR2F1,PGD,PWP1,ATXN7,SPAG9,FAM135A,PALB2,SNAP23,DNAH17,PPP1R12B,ARHGAP12,PRKAR2A,GPR143,RSL1D1,RNF24,ZNF83,PELP1,CAD,UBR1,FSIP2,DNAJB6,ARMC5,C15orf40,ZFP37,CORO1A,AKNAD1,PRMT3,CASP10,SKIV2L,WDR36,EVL,THSD4,MANBAL,AKAP13,ENC1,NUP214,BTBD11,RANBP2,RBBP8,SIX5,CLEC16A,ITGA2,ZNF436,TSSC1,PRRT3,PUS1,NFASC,ZNF589,ATXN7L2,UNC13D,MAP3K13,MAP1S,C14orf159,CSNK1A1,BZW2,IQGAP2,FAM50A,SACS,ANXA7,ZNF561,PRICKLE2,GREB1,DDX31,PCK2,FBXO31,FAM71E1,GINS3,ADAMTSL3,DHX34,TEX14,PEAR1,GPNMB,RHOT2,TMEM175,PIK3CB,CHCHD6,ARMC3,NEU1,CENPP,POLR3G,C20orf196,SRBD1,MSH3,GLG1,ITGB4,MIPOL1,GCSH,MYCBP2,PRDX6,TNFRSF21,PLRG1,TMEM109,ENAH,AARS,UBR5,MGA,PAK1IP1,RNF111,ME1,CEP135,MEIS3,FUT11,SEH1L,TBC1D8,DPF3,ATG9A,NR6A1,NOL8,EYA3,TCEB3,CUX1,MAK16,VPS13D,DNAH2,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,WDR75,IFT57,CELSR1,ZHX3,ANKRD17,OPHN1,ANXA10,IGF2BP3,PRKCE,SLC16A9,IGF2BP1,LPCAT1,TERF2,USE1,SIK3,DDX28,SYNGAP1,AOC2,KIAA0586,TTYH2,PLCB1,ARIH2,DAGLA,EPRS,KIDINS220,SRRD,UBAP1,PMEPA1,ZZEF1,D2HGDH,PEX13,UMPS,RTTN,TRPM2,CCDC58,SPATA2L,URB2,HFM1,C1QTNF7,KLHL18,AP1B1,PDE3A,PHC2,FLAD1,TERF2IP,CHD7,ZNF827,SHC1,KDM2A,VGF,SERPINH1,KMT2A,PLEKHA4,NAA35,RFC4,ZCCHC14,DLG4,KIAA1586,GALK2,MED16,PNN,STK10,DHX57,DCBLD2,VDR,ZNF236,TRMT2A,ANXA2,KLHDC4,MDN1,NOLC1,TROVE2,NCOR2,C10orf2,MRI1,TCF3,ZNF280C,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,NEDD4,ZNF483,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,RDX,UPF2,PLEKHG4,FAM120B,TSHZ1,WDFY3,FZD3,YIF1A,KLHL22,ZDHHC11,HELZ,HNRNPH3,MYOM2,PGAM5,BRWD3,SLC43A1,SLC37A3,PHF3,NF1,KIF5A,FANCD2,TRPM6,PLOD1,ZNF107,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,EDC3,SMARCB1,ZNF804A,RTN1,ANAPC1,LONRF2,YLPM1,THADA,RELB,IPP,POLR3B,PCOLCE2,NDUFA6,CCDC121,PRKACB,LONP1,TIMM50,ZBTB17,LAMA4,GPM6A,SLC38A1,ZNF680,GPCPD1,TCTN1,SERGEF,CHAF1A,TAF9B,CDHR3,PAF1,RHOU,TMEM132B,EPN2,SUFU,TRMT5,DNAJC1,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,VIPR1,RELL2,PIGN,CHST11,AK2,FN1,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,PHGDH,CMTM3,ETFB,CEP164,SIPA1L3,MCAM,ATXN2,SEMA3D,NRIP1,N4BP2,KRT20,PDE4A,TSTA3,TBXAS1,WWC1,PRDM1,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,HK2,EXOC4,KIAA1328,ZFP90,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,CELSR3,MYO7A,ST7L,GBF1,SLC39A1,ZSCAN5A,VPS18,CCDC50,CAMTA2,RPS6KL1,ZNF142,MET,ZNF460,HTRA2,MCEE,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,R3HDM1,ATP8B2,PUSL1,RAB10,RAD54B,TPK1,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SCARB1,HEATR1,USP11,ECHDC1,YDJC,TNIK,SH2D3A,C17orf80,DBF4,NSUN6,CLSTN2,LETMD1,PPHLN1,CCDC7,MFSD10,SFI1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,UTS2,SLC25A1,MSX1,MARS,ARHGAP32,LENG8,MEN1,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ALG5,ZNF330,MBD6,ARHGAP27,HRH1 |
| 3.519e-06 | -12.56 | purine ribonucleoside triphosphate binding | molecular function | GO:0035639 | 1785 | 297 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,NEK6,SYN2,PDS5B,SUCLG2,DPH6,CHD2,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,CARS,EP400,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,PCCA,EIF4A2,IDH3G,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,CDK9,RIOK3,GPN1,MAP2K4,DNM3,ABCA3,MAP2K5,DDX18,ATP6V1A,HFM1,KIAA0232,PDK4,ACTR3,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,GNL1,GALK2,STK10,MAT2A,DHX57,FGFR1,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,BRAF,C10orf2,FARS2,KIF5C,IP6K2,MLH1,OPA1,RPS6KA5,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,RARS,SRCAP,DDX50,HELZ,ORC5,ATM,APAF1,ADK,STK4,MVK,ATRX,RARS2,KIF5A,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,RAN,SLC27A5,YARS,LONP1,PRKACB,TRIP13,SRPK2,TNK2,CHD9,ABCC4,HARS,SKIV2L2,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,ALDH18A1,N4BP2,MTHFD1,CAMKK2,WARS2,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,IRAK2,DNAH17,HK2,RRAGA,BRSK2,TBCK,DDX10,SUCLG1,PAPD4,MYO7A,RIPK1,SMARCA4,DHX35,DDX60L,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,WARS,RAD54B,TPK1,ATP5D,SEPT5,SMG1,TNIK,BCKDK,DNAJA4,MINK1,MAP3K13,CAMK1,ARL15,TKFC,ARFIP2,VARS,CSNK1A1,MFHAS1,GFM2,PIP4K2A,PRKCH,GART,DDX31,PCK2,RPS6KB2,GPHN,SMARCAD1,ABCF2,TEX14,DHX34,MARS,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,MSH3,RPS6KC1,ZAK,KIF1B |
| 3.551e-06 | -12.55 | PATIL_LIVER_CANCER | MSigDB lists | PATIL_LIVER_CANCER | 698 | 131 | 17758 | 2279 |
THOC5,CUL7,DPH1,PRKAB2,ENAH,RNF43,SLC29A1,HLTF,PRKCA,UBR5,ABL2,RPS16,S100A10,RASSF3,NCKIPSD,UBAP2L,ETV1,TRIP13,TMPO,LAMA4,SLC38A6,GDAP1,RBCK1,OSBP2,PPARG,CDK4,TSN,ZDHHC14,TMEM206,CHAF1A,TMCO1,TP53BP1,ARL4A,HIC2,BMI1,PTPN14,FBXO45,MCM6,FAM189B,STXBP6,TRIO,SMG7,ZIC2,XPO7,IGF2BP3,ASAP1,INTS7,MCM5,VPS72,IGF2BP1,GTF3C3,ALDH18A1,LPCAT1,PEA15,FADS1,MSI2,PRIM2,RB1CC1,POLA1,RDH10,XPO5,ZNF512B,ONECUT2,ABCF1,IRS1,DYNC1H1,EHMT2,KIAA0355,FDPS,SQLE,DTD1,KIAA0196,SNX27,ZNF706,RBFOX2,LAGE3,OLA1,SMARCA4,GRINA,TMEM104,SPATS2,IGSF1,SLC39A1,FLAD1,IDI1,DUS4L,SHC1,NUP133,ZKSCAN1,UCHL5,GSTA4,FHIT,PEG10,PXK,TMEM136,MOSPD1,HN1,RFC4,GON4L,TUBA1A,COL5A2,PARP2,VIM,MEF2D,DSP,IFT81,COPS5,HIPK2,ITGA2,H2AFX,ANXA2,TSPAN5,TMCC1,SCAMP3,SESTD1,VARS,AKT1S1,RMI1,STC2,ERI3,C15orf41,CLK2,KDM5B,ARHGAP39,ADSL,IL6R,PTK2,GPNMB,NEU1,DKK1,TMEM237 |
| 3.581e-06 | -12.54 | MORF_DEAF1 | MSigDB lists | MORF_DEAF1 | 57 | 21 | 17758 | 2279 |
DEAF1,CAMKK2,GARS,AK2,SKIV2L2,NPM3,SF3A3,IMPDH2,DKC1,XPO7,TARS,POM121,PABPC4,HDDC2,EPRS,NDUFV1,CDC16,HNRNPR,MRPS27,YARS,NUDC |
| 3.583e-06 | -12.54 | REGULATION_OF_CELLULAR_METABOLIC_PROCESS | MSigDB lists | REGULATION_OF_CELLULAR_METABOLIC_PROCESS | 776 | 143 | 17758 | 2279 |
ZNF76,EIF3C,UBN1,ATRX,PPARGC1B,BCOR,SIRT2,GABPB2,MAP2K3,SMARCB1,SREBF2,PHF5A,ZFHX3,JAZF1,ZEB1,ZNF148,CHD2,HCFC2,CARM1,TNK2,ATF4,NR6A1,LIMA1,PPARG,MED27,CUX1,TCEB3,HDAC8,BRCA1,UBTF,DYRK1B,HPRT1,SUPT4H1,GATA6,SUFU,DNAJC1,CHD3,PER1,MKL2,PQBP1,TNFRSF1A,RUNX1,EGR1,FOXO1,CDC42EP2,ZHX3,KHDRBS1,SMG7,RSF1,SUB1,ZNF354A,VPS72,MYC,BUD31,TIMELESS,GTF2H1,CCDC88C,NRIP1,PABPC1,TERF2,CAMKK2,RREB1,EIF4A2,JMJD1C,ELP3,ARID5B,SMARCD3,PRDM1,EIF2A,ARID1A,SUPT5H,TCF7L2,MYBBP1A,KPNA1,HIF1A,ZNF254,TCF12,ID1,TRERF1,NPAS2,RBFOX2,PBX1,FOSL2,IGSF1,PAIP2,TERF2IP,NRF1,SOCS1,IKBKB,ETF1,MAML3,KAT8,KRT7,TFCP2,EIF3J,MTIF2,ATXN1,POU2F1,ERC1,EIF3H,SMAD3,VDR,RBBP8,ELP2,SMARCC1,KLF4,ARNTL,ATG7,MED20,MAPT,HMGA2,MAP3K13,TCF3,TRAK1,ID2,NFX1,IGF2BP2,ATF7IP,TRIM22,IKBKAP,RPS6KA5,BMP6,FOXO3,ABL1,TADA3,SNW1,PSMG4,SAMD4A,KDM5B,FOXN3,SMARCAD1,KDM5A,MEN1,POLR3G,SRCAP,NSD1,TBX3,SET,RBPJ,BMP4,NR2F2,DDIT3,KAT6A |
| 3.617e-06 | -12.53 | RIGGINS_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 215 | 52 | 17758 | 2279 |
SERINC5,INSIG2,CLK1,KIAA0232,C14orf159,KIF5C,ZFP36L1,SLC1A1,MRPS30,NAMPT,NEBL,PMAIP1,IFIT5,PDE10A,RABGAP1L,DSG2,STC2,WAC,GREB1,ZNF148,PEG10,AKAP11,VPS13B,PMS1,MSX1,PPAT,ARID5B,PTPN12,ATXN1,TMEM123,SATB2,ENC1,PALLD,PLCB1,UBE2K,DSP,DDX60,SYT1,ISG15,RANBP2,KLF4,FAT1,ADAM9,SEMA3C,ARHGAP12,RBPJ,IFITM2,PDLIM5,MMP16,TSPAN5,HS2ST1,TMEM33 |
| 3.630e-06 | -12.53 | KEGG_PURINE_METABOLISM | MSigDB lists | KEGG_PURINE_METABOLISM | 155 | 41 | 17758 | 2279 |
AK2,POLR1A,PDE4B,APRT,PDE3A,POLR3D,AMPD3,GART,ENTPD5,ATIC,PDE10A,NT5C,POLR3B,POLE3,POLR1B,FHIT,NT5M,ZNRD1,POLR1E,PRPS1,NT5E,PDE4A,PRIM2,ITPA,PPAT,POLA1,ADSL,IMPDH2,PDE2A,PDE3B,POLR2A,POLR3A,PDE8B,POLR3G,HPRT1,NME1-NME2,NME7,POLE2,POLR1C,ADK,PDE9A |
| 3.831e-06 | -12.47 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 790 | 145 | 17758 | 2279 |
ARHGAP26,POLB,GYG1,NBEAL1,PRKCA,DST,RAP1A,IKZF5,RABGAP1L,FUT11,PPM1K,CSGALNACT2,DDN,ARRDC3,MSRB3,MCL1,ZDHHC14,SON,SPOP,EPN2,AHNAK,HSDL2,DPP4,ADAM9,GALNT10,CCNB1IP1,NRP1,TPM1,BMI1,DCAF5,SYNPO,LPP,MEF2C,EFNB2,LRRC28,SLK,TGFBR2,CDC73,SPIRE1,MTUS1,SH2B3,TSPAN2,ABCA5,PDE10A,GMDS,CAV2,FMNL2,NT5E,IFRD1,RREB1,MYO10,ARID5B,RAPGEF4,RAP1B,PTPN12,ST6GALNAC3,PRDM1,MBNL2,USP46,IRS1,ATXN7,FAM135A,GTF2A1,NSF,KIAA0355,LEMD3,SNAP23,RIOK3,ZCCHC6,PURB,NCOR1,VMA21,SPRED2,ASH1L,AMOTL1,SYT17,MMRN2,SLC48A1,C1QTNF7,SSBP2,ST3GAL6,PTPRG,PAG1,HSPA1A,TMEM150C,DNAJB6,LPIN2,CORO1A,MGLL,VCL,LYST,ARHGAP17,SSFA2,KRT7,ANKRD33B,TOR1AIP2,VIM,SETD7,DSP,CAMK2D,KLF4,ARL13B,TROVE2,TSPAN5,MAPT,TMEM33,LRCH1,NOSTRIN,SERINC5,ESCO1,PDE4B,RCAN1,SEMA3E,RPS6KA5,FAM49A,IQGAP2,MAN1A1,ATXN7L1,PRKCH,NEBL,PTRF,PVRL3,SELT,SAMD4A,TMC7,VPS37A,CRIM1,USP42,FERMT2,FAM126B,PALLD,PPIP5K2,PDE2A,FOXC1,HSPA1B,ANXA1,INF2,GADD45A,SERINC1,ACOX1,TBX3,MYOM2,ZAK,KIF1B,KDM4C |
| 3.847e-06 | -12.47 | HAN_SATB1_TARGETS_UP | MSigDB lists | HAN_SATB1_TARGETS_UP | 379 | 80 | 17758 | 2279 |
CUL7,TRERF1,NPAS2,DDX19A,LAGE3,SSBP2,TMEM132A,PRKCA,ST3GAL6,CSTA,DENND3,TERF2IP,DST,CD96,MALL,DDX41,THSD4,CUX1,VSNL1,WDHD1,SOX4,C1orf174,TPK1,LSS,GATA6,TMEM101,CLU,NRP1,TMEM158,HMGA2,EP400,CHST11,SULT1C2,FN1,JUP,ZCCHC8,STXBP6,PDE4B,ZFP36L1,QSER1,XPO7,TGFB2,BHLHE40,MFHAS1,MTUS1,FAM192A,ABL1,NOP16,PDE10A,GEMIN4,SYNJ2,LARP4B,HBG2,BDNF,PXN,CRADD,MYO10,AGPAT4,PCCA,PSMC3IP,C8orf33,SYT1,ECH1,TCF7L2,NR2F1,TSR1,PMEPA1,COQ9,VPS37B,SQLE,SLC16A1,DNAJC12,SENP3,NCOR1,POLR1C,ITGB4,PDSS2,RABEP1,KAT6A,CPT1C |
| 3.955e-06 | -12.44 | transcription elongation factor complex | cellular component | GO:0008023 | 45 | 18 | 17570 | 2233 |
BRD4,WDR61,ELP3,TCEB3,IKBKAP,NELFA,SUPT5H,CDC73,PAF1,ELL,SNW1,SUPT4H1,ELP2,CCNT1,CDK9,CTR9,ICE2,ZC3H8 |
| 3.961e-06 | -12.44 | RPS14_DN.V1_DN | MSigDB lists | RPS14_DN.V1_DN | 177 | 45 | 17758 | 2279 |
SRM,DNAJA4,MCM10,ID1,LARS2,KIF5A,C10orf2,SLC25A21,COBLL1,PCSK7,VARS,SLC29A1,CHAC1,SLC6A8,NLE1,CAD,ASNS,GATC,SUV39H2,MCM5,GSTA4,NOC3L,GEMIN4,PRMT3,TRIP13,DDN,LRRC20,PSAT1,AOC2,EYA3,KIF15,TBRG4,TPRA1,GUF1,AGAP1,PYCR1,EXO1,PES1,ALAD,SRD5A3,MACROD1,EIF2B3,GPATCH4,IPO4,SLC43A1 |
| 3.961e-06 | -12.44 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 45 | 17758 | 2279 |
ZNF292,ASCC1,ESCO1,CYLD,FEM1C,ITPRIP,DDX18,CLK1,MYNN,BHLHE40,RLF,MFSD10,DDIT4,PHC2,VPS18,KCTD11,KDM5C,EXOSC4,FUT11,LONP1,SAP30,SF3A1,SEC24A,FAM127A,PDK1,DDX41,IFNGR2,ATG9A,RNMT,ZNF654,LDHA,MAPK1IP1L,STK10,ABCF1,TAF9B,ZBTB25,PLIN2,RANBP2,TCF7L1,DDX50,HLCS,KDM4B,RIOK3,HK2,RBPJ |
| 4.034e-06 | -12.42 | V$YY1_Q6 | MSigDB lists | V$YY1_Q6 | 227 | 54 | 17758 | 2279 |
PRPF38B,ASH1L,PCNT,CELSR3,PRKCSH,WDR13,MYNN,TTI1,CSNK1A1,ENOX1,GBF1,FOXO3,GIT2,GIGYF2,UBE3A,ATP5G2,CACNB2,SLC39A7,ZFP37,ETV1,LYPLA2,SERBP1,SF3A1,CLK2,ATF4,MIOS,KIAA1143,TRA2A,KIF15,TOP3A,POU2F1,SNAP25,DENND4A,NAPEPLD,ECH1,POLR2A,NCDN,TJAP1,EXOC6,DYNC1H1,HIF1A,HNRNPH3,ZZEF1,CAMKMT,HIC2,PPP1R12B,SLC25A19,NCOR1,PREPL,CCNB1IP1,ADK,MAPT,N4BP2L2,LRRC41 |
| 4.094e-06 | -12.41 | Purine metabolism | KEGG pathways | hsa00230 | 174 | 44 | 6908 | 881 |
AK2,POLR1A,AK6,PDE4B,APRT,NT5C3A,PDE3A,AMPD3,POLR3D,GART,ENTPD5,PDE10A,ATIC,NT5C,POLR1B,FHIT,POLE3,POLR3B,ZNRD1,NT5M,POLR1E,PRPS1,NT5E,PDE4A,PRIM2,PPAT,ITPA,POLA1,ADSL,IMPDH2,PDE2A,PDE3B,POLR3A,POLR2A,POLR3G,PDE8B,HPRT1,NME1-NME2,NME7,POLE2,POLR3E,POLR1C,ADK,PDE9A |
| 4.094e-06 | -12.41 | Purine metabolism | KEGG pathways | ko00230 | 174 | 44 | 6908 | 881 |
AK2,POLR1A,AK6,PDE4B,APRT,NT5C3A,PDE3A,POLR3D,AMPD3,GART,ENTPD5,PDE10A,ATIC,NT5C,POLR1B,FHIT,POLE3,POLR3B,NT5M,ZNRD1,POLR1E,PRPS1,NT5E,PRIM2,PDE4A,ITPA,PPAT,POLA1,ADSL,IMPDH2,PDE2A,PDE3B,POLR2A,POLR3A,POLR3G,PDE8B,HPRT1,NME1-NME2,POLE2,NME7,POLR3E,POLR1C,ADK,PDE9A |
| 4.096e-06 | -12.41 | EEF1G (eukaryotic translation elongation factor 1 gamma) | protein interactions | 1937 | 152 | 43 | 16036 | 2270 |
CARS,PRPF38B,CUL7,FN1,KLHL18,VARS,HLTF,MLH1,HMOX2,ENOX1,PDCD5,HNRNPA3,ABL1,SNW1,UCHL5,MYC,PLEKHA4,PABPC1,RPS6KB2,FLNC,SIRT6,HARS,NPM3,RANGAP1,PTK2,DKC1,C1orf174,ARIH2,ECH1,ISG15,SKIL,DLEU1,TRIB3,EPRS,GADD45A,TRAP1,HNRNPH3,COPS5,CUL2,PTPN4,FUS,WDR33,IPO4 |
| 4.136e-06 | -12.40 | TBL3 (transducin (beta)-like 3) | protein interactions | 10607 | 45 | 19 | 16036 | 2270 |
WDR36,NIFK,CUL7,DDX24,DDX18,SIRT7,UTP15,DKC1,NOP58,PUM3,USP36,NOP56,DDX56,MPHOSPH10,NOC3L,POLR1B,USP11,FBL,FTSJ3 |
| 4.146e-06 | -12.39 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4361 | 646 | 17775 | 2278 |
PTP4A1,ARHGAP26,GNB3,ADAM19,ASCC1,DPH1,HLTF,SLC6A8,NUP160,SYNJ1,NOS1AP,PCDH7,SKI,MMP7,ZFHX3,NEK6,PMAIP1,RABGAP1L,FAAH2,RASSF3,MAD1L1,KDM5C,FXN,AVEN,CDK6,NRAS,PTPRM,AKAP12,MCL1,MCM2,ZNF197,DDX3X,SUPT4H1,BRCA2,RAD18,RIOK1,DIRAS1,RUNX1,FIP1L1,LPP,MEF2C,HERC2,CARS,BANP,KHDRBS1,TRIO,SIRT7,PRAF2,NHS,PIK3R4,PLA2G12A,BTBD9,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,SLC38A5,DHX37,MCM5,ANP32B,GEMIN4,MAP3K12,MYB,HMGCR,PEA15,ZNF675,GTF2H3,STAG1,PRDM16,EIF4A2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,IRS1,KPNA1,TRAP1,SURF1,GPN1,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,PYCRL,MMP14,MSH4,TRMT12,PMS1,KMT2D,ARHGEF10,ADAM32,MEF2D,FKBP3,FGFR1,GNG2,TAF2,FBXL5,ARHGAP21,CDC16,KDM4B,ELP2,HIPK2,RPS6KB1,FUS,BRCC3,RAB30,BAG1,TRIM36,HMGA2,XPC,SESTD1,ID2,GAS6,IP6K2,POM121,TADA3,SUV39H2,PTGS1,RAPGEFL1,ARHGAP1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,LDHA,IL6R,FOXC1,DDX49,ANXA1,RPA1,OXSR1,TRIB3,POLE2,HERC1,PTPN4,AEN,BMP4,MTMR1,IGBP1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,WDR13,HECTD3,CSNK2A1,TMEM132A,NLE1,COX10,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,DHX33,PHKA1,XRCC2,NCKIPSD,POLE3,RAN,ZMYM2,ETV1,VPS13B,PTPRK,FMNL3,CHD9,CDK4,TSN,HSPA5,COL4A3BP,GMFB,SUMO3,BRCA1,DLST,FLVCR1,KIF16B,CXADR,MLLT10,DYRK1B,HPRT1,TP53BP1,CHD3,PER1,ARL4A,E2F4,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,HSD17B10,NKD2,MEX3A,LAMTOR3,SMAD7,MAPK8IP3,HES6,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,CAMKK2,TRAPPC9,CRADD,SETD2,OBSCN,MEX3B,NR2F1,VAC14,SPAG9,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,SH3PXD2A,DDX10,PRKAR2A,USP7,SART1,ID1,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,PPP1R9A,KDM1A,FDX1,PLXNB1,METTL16,CAD,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,CORO1A,CASP10,IPO11,SKIV2L,KDM3B,PCGF3,ARHGAP17,RAB7A,VIM,AKAP13,CA5B,ENC1,ARL5B,NUP214,USP36,EIF3H,BTBD11,SMAD3,EXO1,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,AUH,MAP3K13,APRT,CSNK1A1,FOXP1,PTPN2,ADH5,FAM50A,SACS,SURF2,DDX31,FBXO31,CD44,PCK2,C12orf4,AP4S1,ADAMTSL3,SMARCAD1,FOXN3,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,LMBRD2,POLB,MYCBP2,CUL4A,TNFRSF21,PRKAB2,ADAMTS6,PRKCA,IKBIP,RAC3,UBR5,MGA,SUCLG2,CHD2,FAM127A,SETD1B,GNG7,ZDHHC14,DENND4A,PLCXD2,SH3GL1,DOT1L,GNAI1,SPOP,SKIL,TRRAP,CCNT1,FAM122C,HSPBAP1,ZNF81,TNFRSF10D,CCNB1IP1,BMI1,ZMAT3,PTPN14,IFT57,JUP,EGR1,DROSHA,ANKRD17,ST6GAL1,CENPB,OPHN1,SSR4,TGFBR2,PDCD5,CHD5,PRKCE,FKBP1A,NAV1,TSPAN2,PI4KB,NOVA2,MYC,ATIC,COPS3,IGF2BP1,SAMD13,PRPS1,TERF2,DDX28,SIK3,ANAPC13,PRIM2,POLA1,PCCA,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,PHF6,CAT,HIF1A,PMEPA1,SPEN,VCAN,RIOK3,UMPS,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,RTTN,BIRC6,PTPRG,IGSF1,RING1,TERF2IP,PHC2,NUBPL,KDM2A,SHC1,PPID,LPIN2,SOCS6,SERPINH1,PNPLA4,KMT2A,CDK12,PLEKHA4,SAP30,RFC4,BRD4,RFC3,PDK1,PREX1,POLG2,ERC1,STK10,DHX57,BAZ1A,CAMK2D,SMARCC1,G6PD,DNAJA3,FTSJ1,H2AFX,ALKBH1,TRAF3,ANXA2,XRCC4,PDCD11,MID1,NCOR2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,DNAJC22,IKBKAP,NOL3,INPP1,FOXO3,MAD2L2,NEDD4,ABL1,RGS17,COPS7B,NLGN3,S100A14,CLK2,NAV3,TMC7,PXN,APEX1,FZD3,ADSL,FBXO21,ORC5,RNF138,ATM,APAF1,ADK,BRWD3,RABEP1,DDIT3,IPO4,STK4,PIGM,PHF3,ATRX,NF1,PTPRA,TRPM6,FANCD2,RCHY1,SIRT2,BCOR,STK33,SMARCB1,MRPS30,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,ANAPC10,RELB,POLR3B,OGG1,PRKACB,TRIM14,SRPK2,TNK2,TRIM13,SESN2,FBXW4,TXLNG,SIRT6,KSR2,HDAC8,COTL1,PITPNB,MTHFD1L,SOX4,KMT2C,SGK2,SERGEF,TAF9B,RHOU,PAF1,GEMIN5,DNAJC1,PQBP1,CSMD3,ASB3,EME1,CLU,ZC3H8,COPS6,MTCH1,FBXO45,PIGN,AK2,RHOBTB1,TAF1,PCSK7,MED13L,XPO7,DDIT4,RNF141,ELL,N4BP2,AKAP11,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,SYT1,UBE2E1,POP1,HK2,TBL1X,FNBP1L,TBCK,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,PBX1,SMARCA4,DHX35,RIOK2,BRE,SOCS1,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,ITGAX,MET,VCL,GNG5,MOSPD1,TMLHE,PARP2,METTL2A,DKC1,UBR4,RAB10,RAD54B,IKZF4,KPNA3,COPS5,DUSP19,FKBP5,RNF130,SCARB1,USP11,SMG1,DNAJC2,BCKDK,TNIK,DNAJA4,SH2D3A,CAMK1,DYM,DBF4,ATF7IP,MED18,IGF2BP2,PPP1R1C,PIP4K2A,FAM49A,PRKCH,CTNNBL1,TANK,AMOT,TOP1,RPS6KB2,KDM6B,DNMBP,IL11RA,GPHN,FGF2,KDM5A,MARS,ARHGAP32,TMEM187,NAPEPLD,GADD45A,CUL2,NFKBIB,ZAK,MMP16 |
| 4.212e-06 | -12.38 | WD40_repeat | interpro domains | IPR001680 | 268 | 61 | 18293 | 2341 |
DMXL2,WDR75,GNB3,PAFAH1B1,WDR74,WDR13,PLRG1,PIK3R4,PPP2R2A,WDR26,WDR37,NUP43,CORO6,NBEAL1,DENND3,NLE1,AMBRA1,PEX7,WDR27,NBEA,PAK1IP1,WDR60,CORO1A,UTP4,SEH1L,LYST,PRPF19,WDR36,FBXW4,WDR61,MIOS,WDFY3,TLE3,WDR18,UTP15,WDHD1,WDR25,MED16,NUP214,GEMIN5,SEC31A,PWP1,NOL10,WDR5B,ELP2,WDR35,HERC1,WDR73,TECPR2,BCAS3,WDR7,TSSC1,IFT140,PRPF4,TBL1X,APAF1,WDR66,WDR33,BRWD3,DCAF5,CORO2B |
| 4.216e-06 | -12.38 | NOP56 (NOP56 ribonucleoprotein) | protein interactions | 10528 | 162 | 45 | 16036 | 2270 |
NIFK,CUL7,UTP14A,DDX18,RSL1D1,CSNK2A1,SMARCA4,DDX56,MPHOSPH10,RPS16,EIF2S2,PTRF,MYC,GLYR1,SHMT2,EXOSC4,IGF2BP1,POLR1B,FBL,FTSJ3,HNRNPM,TOP1,WDR36,SNU13,TUBA1A,DDX24,GNL3,ABCF2,NOL6,NFIA,DKC1,KLF6,RBM28,NOP58,PUM3,UBC,PES1,PWP1,POP1,DDX50,KPNA1,MYBBP1A,COPS5,NOLC1,SRP14 |
| 4.297e-06 | -12.36 | GAR1 (GAR1 homolog, ribonucleoprotein) | protein interactions | 54433 | 34 | 16 | 16036 | 2270 |
SHQ1,FN1,DDX18,TRA2A,USP10,BRCA1,DKC1,CLNS1A,GEMIN5,TSR1,RNF2,RIOK1,GEMIN4,PRMT5,POLR1C,SRP14 |
| 4.428e-06 | -12.33 | methyltransferase activity | molecular function | GO:0008168 | 212 | 52 | 16491 | 2164 |
ASH1L,KMT2E,NSUN6,CIAPIN1,METTL16,GART,SUV39H2,TRMT13,TRMU,ALKBH8,METTL8,FBL,TRMT10A,PRMT5,KMT2A,COQ3,PRMT3,FTSJ3,CARM1,METTL1,KMT2D,SETD1B,RNMT,ALDH1L2,SETD2,EHMT1,METTL23,METTL2A,PCMT1,WBSCR22,METTL15,PRDM1,SETD7,MEN1,METTL22,KMT2C,MTR,DOT1L,NSD1,EHMT2,TRMT5,METTL6,PEMT,CAMKMT,FTSJ1,TRMT2A,TRMT10B,NDUFAF5,SETD6,SMYD3,METTL2B,GCSH |
| 4.431e-06 | -12.33 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta) | protein interactions | 7529 | 341 | 79 | 16036 | 2270 |
BCCIP,CGN,MYCBP2,CUL7,CYLD,LUZP1,NF1,CSNK2A1,RADIL,STAM,GBF1,HSPA1A,EDC3,TBC1D22A,PPFIBP1,IKBKB,NCKIPSD,RMDN3,SRRM2,DENND1A,LYST,SRPK2,PHLDB2,LIMA1,SKIV2L2,HSPA5,R3HDM1,AKAP13,DENND4A,SON,TTC28,CHAF1A,SNCA,EXO1,SH3RF1,G6PD,H2AFX,SLC4A7,RIOK1,CEP170,ANKS1A,PTPN14,PARD3,MAPT,MINK1,BRAF,FN1,ZCCHC8,SLK,KLC4,PIK3R4,TKFC,ZFP36L1,AKT1S1,FOXO3,GIGYF2,DDIT4,ABL1,SIPA1L3,NAV1,KIAA1671,PI4KB,MYC,SAMD4A,SIK3,WWC1,MEX3B,R3HDM2,NELFA,PDE3B,UBC,HSPA1B,PGD,IRS1,KIAA0355,ITGB4,SH3PXD2A,ZAK,KIF1B |
| 4.533e-06 | -12.30 | REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM | MSigDB lists | REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM | 167 | 43 | 17758 | 2279 |
NCOR2,NPAS2,PRKAB2,TNFRSF21,PPARGC1B,MED13L,MED18,LCLAT1,LPIN1,SLC25A20,DECR1,NRF1,SREBF2,LPIN2,MED24,ME1,LPCAT1,HSD17B12,SLC25A1,FDFT1,HMGCR,ACSL5,MCEE,ACADS,FADS1,PPARG,TEAD1,AGPAT4,PCCA,ELOVL6,MED27,SMARCD3,MED16,CPT1A,ANGPTL4,PLIN2,TRIB3,ACOX1,ARNTL,GPAM,NCOR1,MED20,TBL1X |
| 4.555e-06 | -12.30 | MODULE_110 | MSigDB lists | MODULE_110 | 16 | 10 | 17758 | 2279 |
CARS,EPRS,SARS,GARS,NARS,HARS,HARS2,VARS,YARS,AARS |
| 4.607e-06 | -12.29 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4290 | 636 | 17775 | 2278 |
ARHGAP26,PTP4A1,ADAM19,ASCC1,GNB3,DPH1,HLTF,SLC6A8,NUP160,SYNJ1,NOS1AP,SKI,PCDH7,MMP7,NEK6,PMAIP1,FAAH2,RABGAP1L,RASSF3,MAD1L1,KDM5C,FXN,AVEN,CDK6,NRAS,PTPRM,AKAP12,MCL1,MCM2,ZNF197,DDX3X,BRCA2,SUPT4H1,RAD18,DIRAS1,RIOK1,RUNX1,FIP1L1,LPP,MEF2C,CARS,BANP,HERC2,KHDRBS1,SIRT7,TRIO,PRAF2,NHS,PIK3R4,BTBD9,PLA2G12A,PDCD7,PITPNM1,CHN1,DDX56,UBE3A,DHX37,SLC38A5,MCM5,ANP32B,GEMIN4,MAP3K12,MYB,HMGCR,ZNF675,PEA15,GTF2H3,STAG1,PRDM16,EIF4A2,USP10,SMARCD3,IMPDH2,TRIM37,USP46,IRS1,KPNA1,TRAP1,SURF1,GPN1,ARHGAP10,SPRED2,TRERF1,DDX18,PDK4,DDR2,CD99L2,MYH9,FAM122B,NUP43,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ACD,MMP14,MSH4,TRMT12,PMS1,KMT2D,ARHGEF10,ADAM32,MEF2D,FKBP3,FGFR1,GNG2,TAF2,FBXL5,ARHGAP21,CDC16,ELP2,KDM4B,HIPK2,RPS6KB1,FUS,BRCC3,BAG1,RAB30,TRIM36,HMGA2,XPC,SESTD1,ID2,GAS6,IP6K2,POM121,TADA3,SUV39H2,PTGS1,ARHGAP1,RAPGEFL1,FBXL19,FBXO17,DDX24,POLK,ZC4H2,LDHA,IL6R,DDX49,FOXC1,ANXA1,RPA1,OXSR1,TRIB3,POLE2,HERC1,PTPN4,AEN,BMP4,IGBP1,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,TRIM16,WDR13,HECTD3,CSNK2A1,TMEM132A,COX10,NLE1,GIT2,BIRC2,MAP2K3,ABL2,AMPD3,SRSF2,ARHGAP18,COPS4,PHKA1,DHX33,XRCC2,NCKIPSD,RAN,POLE3,ZMYM2,ETV1,PTPRK,VPS13B,FMNL3,CHD9,CDK4,TSN,HSPA5,GMFB,COL4A3BP,SUMO3,BRCA1,DLST,CXADR,MLLT10,KIF16B,DYRK1B,HPRT1,TP53BP1,CHD3,ARL4A,E2F4,PER1,SOCS4,TNFRSF1A,RAD51B,ADAM9,PPP3CC,MAGI1,USP15,PGPEP1,MCM6,FOXO1,CLK1,NKD2,SMAD7,LAMTOR3,MEX3A,HSD17B10,MAPK8IP3,HES6,RNF40,MBD2,GTF2H1,VAPB,SYNJ2,TRAPPC9,CAMKK2,CRADD,SETD2,OBSCN,MEX3B,NR2F1,VAC14,SPAG9,PALB2,SNX24,PPP1R12B,ARHGAP12,PTP4A2,DDX10,SH3PXD2A,PRKAR2A,USP7,SART1,ID1,GPR143,LAGE3,PPP2R2A,RIPK1,RNF24,PPP1R9A,PLXNB1,FDX1,KDM1A,CAD,METTL16,ZNF608,JAG1,NUP133,GRIN2C,IKBKB,ETF1,RNF2,CORO1A,IPO11,CASP10,KDM3B,SKIV2L,ARHGAP17,PCGF3,RAB7A,VIM,AKAP13,CA5B,ENC1,NUP214,ARL5B,EIF3H,USP36,EXO1,SMAD3,RANBP2,RBBP8,LMBR1L,KLF4,ITGA2,MED20,SEPT5,MUTYH,ZNF507,MCM10,AUH,MAP3K13,APRT,FOXP1,CSNK1A1,PTPN2,ADH5,FAM50A,SACS,SURF2,DDX31,CD44,FBXO31,PCK2,C12orf4,AP4S1,ADAMTSL3,FOXN3,SMARCAD1,TPM4,TEX14,TOP3A,DHX34,RAP1GDS1,ARHGEF12,PIK3CB,ZRANB3,DKK1,SET,CSRNP1,MSH3,DNAJC12,USP20,RBPJ,ITGB4,NR2F2,RPS6KC1,XPO6,POLB,MYCBP2,CUL4A,PRKAB2,TNFRSF21,ADAMTS6,IKBIP,PRKCA,RAC3,UBR5,MGA,SUCLG2,CHD2,FAM127A,SETD1B,GNG7,ZDHHC14,DENND4A,PLCXD2,DOT1L,SPOP,SH3GL1,GNAI1,SKIL,TRRAP,FAM122C,CCNT1,HSPBAP1,ZNF81,CCNB1IP1,TNFRSF10D,BMI1,ZMAT3,PTPN14,IFT57,DROSHA,JUP,EGR1,ANKRD17,ST6GAL1,CENPB,OPHN1,SSR4,TGFBR2,PDCD5,CHD5,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,NOVA2,COPS3,MYC,ATIC,SAMD13,IGF2BP1,PRPS1,TERF2,SIK3,DDX28,PRIM2,ANAPC13,PCCA,POLA1,RAPGEF4,RAP1B,PTPN12,ARID1A,PLCB1,PHF6,CAT,HIF1A,PMEPA1,VCAN,SPEN,RIOK3,UMPS,NCOR1,IQSEC2,DHCR7,MAP2K4,SMYD3,VMA21,BIRC6,PTPRG,RING1,IGSF1,PHC2,NUBPL,TERF2IP,SHC1,KDM2A,PPID,LPIN2,SOCS6,PNPLA4,SERPINH1,KMT2A,PLEKHA4,CDK12,SAP30,RFC4,RFC3,BRD4,PDK1,PREX1,POLG2,STK10,ERC1,DHX57,BAZ1A,CAMK2D,SMARCC1,G6PD,DNAJA3,FTSJ1,H2AFX,ALKBH1,TRAF3,ANXA2,PDCD11,XRCC4,MID1,NCOR2,BRAF,UTP14A,TCF3,ZNF280C,MLH1,NOL3,IKBKAP,DNAJC22,INPP1,FOXO3,NEDD4,MAD2L2,ABL1,RGS17,COPS7B,NLGN3,S100A14,CLK2,NAV3,PXN,APEX1,FZD3,ADSL,FBXO21,ORC5,RNF138,ATM,APAF1,BRWD3,ADK,RABEP1,IPO4,DDIT3,STK4,PIGM,PHF3,NF1,ATRX,PTPRA,FANCD2,TRPM6,RCHY1,SIRT2,BCOR,STK33,MRPS30,SMARCB1,ANAPC1,RAP1A,THADA,JAZF1,ANAPC11,ANAPC10,RELB,OGG1,TRIM14,PRKACB,SRPK2,TNK2,SESN2,TRIM13,FBXW4,TXLNG,SIRT6,KSR2,HDAC8,MTHFD1L,COTL1,PITPNB,SGK2,SOX4,KMT2C,SERGEF,TAF9B,GEMIN5,RHOU,SUFU,DNAJC1,PQBP1,CSMD3,ASB3,CLU,EME1,ZC3H8,COPS6,MTCH1,FBXO45,AK2,PIGN,RHOBTB1,TAF1,PCSK7,MED13L,XPO7,DDIT4,RNF141,ELL,N4BP2,AKAP11,MSI2,RANBP6,XPO5,JMJD1C,LIG4,PRDM1,SYT1,UBE2E1,HK2,TBL1X,FNBP1L,TBCK,TCF12,SNX27,DLL4,ASH1L,PSTPIP2,PIGH,SMARCA4,PBX1,DHX35,RIOK2,BRE,SOCS1,RPS6KL1,PPFIBP1,SLC38A2,ADCK4,ITGAX,MET,GNG5,MOSPD1,TMLHE,PARP2,METTL2A,DKC1,UBR4,RAB10,RAD54B,IKZF4,KPNA3,COPS5,DUSP19,FKBP5,SCARB1,RNF130,USP11,SMG1,DNAJC2,BCKDK,TNIK,DNAJA4,SH2D3A,DYM,CAMK1,DBF4,MED18,ATF7IP,IGF2BP2,PPP1R1C,FAM49A,PIP4K2A,PRKCH,CTNNBL1,TANK,AMOT,TOP1,RPS6KB2,KDM6B,DNMBP,IL11RA,GPHN,FGF2,KDM5A,MARS,ARHGAP32,TMEM187,NAPEPLD,GADD45A,CUL2,NFKBIB,ZAK,MMP16 |
| 4.680e-06 | -12.27 | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | 9663 | 1337 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,THOC5,DPH1,CNTNAP3,DCP1B,AARS2,SBF2,CCNL2,SLC6A8,SKI,PDZD2,MMP7,ZFHX3,THAP4,LETM2,MAD1L1,KDM5C,SRRM2,PPM1K,CCDC57,NRAS,LIMA1,UPP1,NFIA,C5AR1,WDHD1,MCM2,SLC9A5,ZNF197,PYCR1,AHNAK,SSU72,RAD18,DIRAS1,RIOK1,RUNX1,VASH2,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PITPNM1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,WDR60,GEMIN4,CCDC88C,PABPC1,ANGPT2,MYB,NOM1,KLRD1,ZNF675,IFRD1,STAG1,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,ATAT1,USP10,MAP7D1,ST6GALNAC3,TRIM37,SRA1,USP46,IRS1,DYNC1H1,TSR1,KPNA1,EHMT2,TRAP1,CCDC85B,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,PAFAH1B1,C16orf45,DDR2,CD99L2,FAM122B,GRINA,NUP43,MCM9,RPGRIP1L,ZBED2,ZSWIM7,ACD,TBC1D22A,MMP14,INTS12,MSH4,PEG10,TRMT12,ZC3H3,KIAA1549,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,MEF2D,GSTCD,DSP,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,ARL13B,CAMKMT,RPS6KB1,CEP170,METTL2B,CATSPERG,BAG1,RAB30,HMGA2,SHQ1,ATG2B,GAS6,IP6K2,TRIM22,PSMF1,TTLL11,PSMG4,TAF3,CFDP1,UNC13A,PTGS1,RAPGEFL1,ZNF710,FBXL19,SAMD4A,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,NXN,CCDC113,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,ZNF3,ZMYM2,FAM184A,VPS13B,DBN1,FMNL3,CDK4,ANK2,HSPA5,TSN,SUMO3,DLST,CXADR,MLLT10,BSN,DYRK1B,HPRT1,CHD3,ARL4A,E2F4,ADAM9,PPP3CC,PRPF4,MAGI1,USP15,CTU2,FOXO1,CLK1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ZIC2,ARID1B,RNFT2,CEP290,MBD2,NDRG4,VAPB,PNPLA3,LRSAM1,SNX29,WARS2,USP49,SETD2,OBSCN,METTL22,TCF7L2,TBC1D2,PRPF40B,TTC38,SNX24,PTP4A2,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,ID1,UPK3B,ARID2,NDUFAF2,NTSR1,LAGE3,RIPK1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,URB1,PLXNB1,FDX1,ZNF608,ANKRD13A,IDI1,JAG1,NUP133,GRIN2C,ANKRD24,CCDC40,MYH15,IPO11,KDM3B,ARHGAP17,AKAP8L,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,ZNF251,EXO1,LMBR1L,KLF4,INTS9,MED20,EIF2B3,MUTYH,ZNF507,MCM10,HM13,ESCO1,AUH,APRT,VARS,RBM19,FOXP1,ADH5,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,TOP3A,ARHGEF12,PALLD,POLR3A,DKK1,TAF4,TBX3,CSRNP1,FNTB,USP20,TMEM219,ZNF32,RBPJ,NR2F2,XPO6,KIF1B,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,ZNF646,ACADS,GDAP1,FAM127A,OSBP2,EFHC1,ZDHHC14,DENND4A,SON,PLCXD2,GNAI1,OSBPL1A,SPOP,DOT1L,TRRAP,CCNT1,HSPBAP1,ARL6IP5,XPNPEP1,NRP1,TNFRSF10D,WDR66,BMI1,SPOCK2,ZMAT3,NMD3,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,CENPB,DPM3,PRPF39,SSR4,PDCD5,MTUS1,TECTA,HR,SLC7A11,NOVA2,SCAF1,MYC,PIGG,MFAP2,RTFDC1,FDFT1,PRIM2,ANAPC13,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,ZNF850,PHF6,ATP9B,CAT,ASCC3,C6orf141,ALKBH3,HIF1A,VCAN,SPEN,MED15,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,DHCR7,SMYD3,CPT1C,VMA21,SYT17,BIRC6,UROD,TMEM104,PTPRG,FLNB,IGSF1,RING1,NUBPL,SLX4,PPID,LPIN2,SOCS6,SHF,TTC3,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PCMT1,PREX1,MARCH6,ERC1,ZBTB25,BAZ1A,CAMK2D,SMARCC1,G6PD,FTSJ1,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,XRCC4,MID1,BRAF,RCAN1,DNAJC22,INPP1,GIGYF2,FAM8A1,ABL1,NEBL,ELP5,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,ADSL,PACS1,BMS1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,ADK,IPO4,DDIT3,IMMP2L,PIGM,EIF3C,ATRX,DST,JAZF1,ANAPC11,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,CARM1,SRPK2,TNK2,DEAF1,FBXW4,SESN2,SKAP2,SIRT6,VWCE,KSR2,PITPNB,COTL1,MTHFD1L,SGK2,KMT2C,TIMM44,HLCS,CTAGE5,CSMD3,ASB3,EME1,CLU,ZC3H8,MTCH1,FBXO45,RHOBTB1,SCART1,PCSK7,SMG7,QSER1,EVPL,RNF141,ELL,ISPD,PRF1,ZCCHC7,LRP3,AKAP11,MTHFD1,MSI2,ZNF234,XPO5,JMJD1C,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,POP1,SYCP2L,FSCN1,FAT1,KIAA0754,TBL1X,FNBP1L,TBCK,PDE9A,N4BP2L2,TCF12,DMXL2,SNX27,DLL4,FEZ2,PSTPIP2,PIGH,TNXB,SMARCA4,TBCCD1,PBX1,TMEM177,SPATS2,ARSJ,DHX35,SBDS,RIOK2,RAET1E,RRN3,MPHOSPH10,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,VCL,GNG5,AUP1,MAML3,NPW,METTL2A,ATXN1,MRRF,METTL15,DKC1,UBR4,S100A16,ARMC4,KPNA3,IKZF4,DUS3L,ZNF557,CEBPZ,ARNTL,DUSP19,FKBP5,ARC,RNF130,NFRKB,BRD9,SMG1,TMCC1,DNAJC2,BCKDK,CAMK1,DYM,VPS45,ATF7IP,IGF2BP2,CHCHD10,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,FAM49A,PEX7,DCTN4,LDLRAD3,FBL,MICAL3,RPS6KB2,TOP1,KDM6B,DNMBP,GPHN,FGF2,ZNF821,PSPC1,KDM5A,SULT4A1,ASAP3,ZNF324B,TMEM187,EIF5B,NAALADL2,CTIF,DAGLB,GADD45A,WDR35,VPS37B,NFKBIB,ZSWIM6,GNB3,ASCC1,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,C1orf159,NEK6,SREBF2,SYN2,PMAIP1,RABGAP1L,RASSF3,FAAH2,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,RFX2,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,STOML2,DDX3X,BRCA2,SUPT4H1,FIP1L1,MEF2C,LPP,HERC2,CARS,EP400,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,YARS2,ABCA7,SLC39A11,DDX56,KIAA1671,SLC38A5,MCM5,ANP32B,AGL,MAP3K12,COQ3,FMNL2,SERBP1,HMGCR,PEA15,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,MBNL2,ABCF1,ZNF655,VPS13C,LRP1B,TASP1,GTF2A1,LEMD3,SURF1,GPN1,SPRED2,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,PDK4,MYH9,AGAP6,NECAP1,SAFB2,EEA1,STAM,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,FMNL1,GSTA4,CEP63,KRT7,FAM111B,ARHGEF10,ADAM32,TTC28,FKBP3,FGFR1,PDE8B,TAF2,GNG2,PES1,CDC16,IQCH,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,LAMA5,YEATS2,LRCH1,TRIM36,ZNF786,XPC,SESTD1,TRAK1,ID2,SF3A3,WDR37,AKT1S1,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,PVRL3,ARHGAP1,DDHD1,C21orf58,FBXO17,ERICH1,POLK,ARHGAP39,MRPS10,IL6R,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,TRIB3,BAZ2B,PXDN,POLE2,PLPPR2,STX1A,PTPN4,SLCO5A1,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,BCAS4,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,TMEM132A,COX10,SEC16A,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,PPCDC,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,TMPO,FLNC,CHD9,GCNT2,BAZ2A,MED27,GMFB,COL4A3BP,BRCA1,ZNF91,KIF16B,PEX1,GLS,MSRA,ZNF622,TP53BP1,PER1,EEFSEC,CCDC146,SOCS4,TNFRSF1A,RAD51B,TMEM158,CHMP4C,NOMO3,AOC3,PGPEP1,MCM6,LRRC28,HSD17B10,MEX3A,HES6,ZFP36L1,DNAH1,DOPEY1,RNF40,KIAA1958,PDE10A,SAMD11,GTF2H1,SYNJ2,GMDS,TRAPPC9,CAMKK2,LAMC1,CRADD,HOMER2,UTP15,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,VAC14,NR2F1,SPAG9,FAM135A,PALB2,DNAH17,ZNF430,PPP1R12B,ARHGAP12,NAPA,PRKAR2A,CYLD,GPR143,PPP2R2A,RNF24,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,UBR1,IKBKB,C15orf40,ZDHHC6,ETF1,RNF2,ANO8,ZFP37,CORO1A,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,PCGF3,EVL,GLTSCR2,THSD4,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,BTBD11,SMAD3,RANBP2,RBBP8,ITGA2,TSSC1,PRRT3,PUS1,SEPT5,ATXN7L2,UNC13D,MAP3K13,FAM46B,MAP1S,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,PRICKLE2,HIST2H3D,DDX31,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,TPM4,DHX34,TEX14,RAP1GDS1,PEAR1,C11orf49,PIK3CB,CHCHD6,ARMC3,NEU1,ZRANB3,GPC2,SRBD1,SET,MSH3,DNAJC12,ITGB4,RPS6KC1,POLB,MYCBP2,CGN,PRKAB2,TNFRSF21,ENAH,ADAMTS6,IKBIP,RAC3,UBR5,AARS,MGA,GIPR,VPS52,PAK1IP1,ME1,CEP135,SEH1L,SETD1B,ATG9A,ALDH1L2,GNG7,CUX1,FOXRED1,MAK16,SH3GL1,SKIL,FAM122C,ZNF81,VPS13D,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,PTPN14,IFT57,DROSHA,EGR1,CELSR1,ANKRD17,ZHX3,OPHN1,PID1,TGFBR2,CHD5,CD226,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,COPS3,ATIC,VWDE,SLC16A9,SAMD13,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,POLA1,KIAA0586,TTYH2,PTPN12,PLCB1,EPRS,KIDINS220,NSF,PMEPA1,ZZEF1,RIOK3,UMPS,TMEM254,IQSEC2,MACROD1,MAP2K4,RTTN,AMOTL1,TRPM2,NDUFB5,C1QTNF7,KLHL18,SPATS2L,TM4SF19,FOSL2,SLC25A44,AP1B1,TRIM66,PDE3A,PHC2,CHD7,TERF2IP,TMEM184A,SHC1,KDM2A,GLYR1,VGF,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,NAA35,RFC4,ZCCHC14,RFC3,PDK1,MTIF2,WDPCP,DLG4,MED16,POLG2,STK10,DHX57,CPED1,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NOLC1,NCOR2,TMEM212,CA11,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,SLC25A12,MLH1,IKBKAP,NOL3,FOXO3,NEDD4,MAD2L2,ZNF239,RGS17,PTRF,NISCH,PMPCA,UPF2,COPS7B,NLGN3,LARP4B,FAM120B,TSHZ1,WDFY3,FZD3,KCNMA1,OASL,YIF1A,FBXO21,ZDHHC11,HELZ,RNF138,MYOM2,BRWD3,RABEP1,STK4,LRRC41,PHF3,FEM1C,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,RCHY1,ZNF107,ANKRD18A,SIRT2,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,ZNF804A,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ANAPC10,RELB,POLR3B,PCOLCE2,SLC27A5,OGG1,TRIM14,PRKACB,TIMM50,LAMA4,TRIM13,TXLNG,CMIP,ZNF680,HDAC8,SOX4,SERGEF,CDHR3,TAF9B,RHOU,GEMIN5,TMEM132B,EPN2,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,COPS6,DMTF1,TNRC6A,SLC12A7,AK2,PIGN,CHST11,FN1,TAF1,MED13L,XPO7,PHGDH,ETFB,DDIT4,CEP164,SIPA1L3,ATXN2,SEMA3D,CCDC112,NRIP1,N4BP2,CPSF3L,KRT20,RANBP6,PDE4A,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,UBAP2,ATAD5,EP400NL,INTS5,SDCCAG8,HK2,EXOC4,KIAA1328,C12orf45,C7orf26,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MYO7A,CSTA,GBF1,ZSCAN5A,VPS18,BRE,CAMTA2,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,TMEM14C,MOSPD1,TMLHE,MCEE,PHLDB2,COL5A2,FAM172A,TFCP2,PARP2,SFSWAP,R3HDM1,RAB10,PUSL1,RAD54B,ZC3H12A,COPS5,DISP1,SCARB1,HEATR1,USP11,TNIK,DNAJA4,SH2D3A,DBF4,CLSTN2,PPP1R1C,SFI1,MAN1A1,PRKCH,GART,CTNNBL1,HAS3,TANK,TTC17,AMOT,PAQR6,IL11RA,ANKMY2,MARS,PHACTR2,ARHGAP32,LENG8,ZNF407,NAPEPLD,HSPA1B,ZNF708,CUL2,ZRANB2,ZAK,MMP16,HRH1 |
| 4.711e-06 | -12.27 | tRNA modification | biological process | GO:0006400 | 66 | 23 | 16441 | 2138 |
CTU2,METTL1,ELP3,AARS2,TYW1,METTL2A,LAGE3,AARS,EPRS,PUS3,DUS4L,DUS3L,TRMT5,TRMT13,ADAT2,TRMU,ALKBH8,FTSJ1,CDKAL1,PUS1,TRMT10A,TRMT12,METTL2B |
| 4.816e-06 | -12.24 | malignant_melanoma | COSMIC cancer mutations | malignant_melanoma | 16732 | 2189 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,PREX1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SRRD,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 4.854e-06 | -12.24 | cerebellum | COSMIC cancer mutations | cerebellum | 801 | 146 | 17775 | 2278 |
GGT1,PRKCSH,NF1,ATRX,TNFRSF21,TRPM6,SBF2,LPAR3,PCDH7,SMARCB1,CNIH3,MAD1L1,SPAG6,CEP128,VPS13B,NRAS,TXLNG,PTPRM,ANK2,AKAP12,KMT2C,ZDHHC14,SON,GNAI1,ARPC3,DOT1L,DDX3X,SUFU,CSMD3,SEMA3C,RUNX1,MAGI1,NRP1,SPOCK3,USP15,STX8,ANKRD17,NKD2,NHS,MTUS1,KIAA1958,TSPAN2,PDE10A,ATXN2,MYB,BDNF,TRAPPC9,PRIM2,PRDM16,PCCA,RAPGEF4,RYR2,CORIN,PLCB1,EHBP1,AGAP1,ACOXL,DNAH14,UBE2E1,DYNC1H1,LRP1B,TASP1,NME7,CDKAL1,SLC16A1,KIAA1328,BPNT1,NCOR1,DDX10,SH3PXD2A,ARHGAP10,COG5,SYT17,SMARCA4,PPP1R9A,ABCA12,TBC1D22A,PPFIBP1,CLCN6,MET,DENND1A,KIAA1549,ZCCHC14,KMT2D,GARS,PTBP2,TFCP2,THSD4,POU2F1,SLC35F2,MEGF11,GALK2,MARCH6,ERC1,BTBD11,RAD54B,TPK1,CAMK2D,ASTN2,ABHD3,ITGA2,RNF130,USP11,XRCC4,SMG1,PARD3,HMGA2,SSH2,BRAF,AUH,TTC27,ARL15,CLSTN2,RCAN1,ATF7IP,SEMA3E,ENOX1,FOXP1,RSRC1,MBNL1,NEDD4,FAM50A,PEX7,NEBL,CFDP1,ANXA5,C15orf41,SAMD4A,FER1L5,TSHZ1,ERICH1,WDFY3,AGPAT4,SCMH1,MEN1,PALLD,ZNF407,NAALADL2,PIK3CB,HELZ,MSH3,BCAS3,SLCO5A1,SORCS2,MIPOL1,HRH1 |
| 4.878e-06 | -12.23 | DOUGLAS_BMI1_TARGETS_UP | MSigDB lists | DOUGLAS_BMI1_TARGETS_UP | 536 | 105 | 17758 | 2279 |
PTP4A1,SNX27,NDUFA5,SPRED2,ASH1L,LUZP1,SUCLG1,NPAS2,POLR1A,SLC2A1,PLOD1,SLC29A1,TUBB6,NUP43,BCOR,LPAR3,KDM1A,ECM1,S100A10,PMAIP1,CORO1A,PEG10,IPO11,CARM1,ARHGAP17,EIF4E3,ATG9A,VWCE,DLG4,DSP,NUDT15,TBC1D16,TMEM206,DCBLD2,SLC39A14,UBTF,CCDC3,MSX2,DUS3L,DCXR,CHD3,LSM14A,ARL13B,POLR3E,SOCS4,FTSJ1,SCARB1,TPM1,SEPT5,TNFRSF10D,RBP1,TNRC6A,NCOR2,FN1,B4GALT5,TCF3,DLGAP4,LAMTOR3,MED13L,ZIC2,AKT1S1,ARID1B,FAM49A,HR,MCAM,TRIAP1,RDX,CLDND1,CPNE7,PRMT5,MAP3K12,LPCAT1,TOMM34,PCSK6,MYB,ADARB1,PEA15,VOPP1,PDE4A,IL11RA,TEAD1,ZBED4,PSMC3IP,OBSCN,MAPK1IP1L,CYB5B,CDH24,KPNA1,FAM135A,MYBBP1A,SRD5A3,HK2,SLC16A1,GPN1,AEN,CNOT6,RBPJ,PGAM5,PTP4A2,NR2F2,SH3PXD2A,MTMR1,DOCK6,PDE9A,CTXN1 |
| 4.938e-06 | -12.22 | PHD | pfam domains | PF00628 | 53 | 20 | 16629 | 2165 |
DPF3,PHF3,KMT2D,KDM5B,KMT2E,BAZ2A,KDM5A,DPF2,RSF1,KMT2C,CHD5,TRIM66,BAZ1A,BAZ2B,TAF3,CHD3,INTS12,KDM5C,KMT2A,KAT6A |
| 4.938e-06 | -12.22 | HALLMARK_MYC_TARGETS_V2 | MSigDB lists | HALLMARK_MYC_TARGETS_V2 | 58 | 21 | 17758 | 2279 |
SRM,DDX18,WDR74,GNL3,CDK4,TBRG4,NOP56,DCTPP1,PES1,FARSA,MYBBP1A,MPHOSPH10,NOP16,MYC,MCM5,HK2,PUS1,NOLC1,PRMT3,IPO4,RABEPK |
| 5.221e-06 | -12.16 | MAX (MYC associated factor X) | protein interactions | 4149 | 70 | 25 | 16036 | 2270 |
ZBTB17,BANP,EP400,KMT2D,TUBA1A,TXLNG,TAF1,TEAD1,TCF3,CUX1,CSNK2A1,HSPA1A,MGA,SMAD3,DYNC1H1,SPAG9,TRRAP,HIF1A,CCNT1,ARL6IP5,MYC,COPS5,MAD1L1,FUS,KDM5C |
| 5.256e-06 | -12.16 | MODULE_3 | MSigDB lists | MODULE_3 | 382 | 80 | 17758 | 2279 |
PTP4A1,UBN1,SMARCA4,SLC29A1,GYG1,RAC3,BIRC2,LPIN1,CAD,SRSF2,SLC39A7,AP1M1,SSBP1,POLE3,SERPINH1,MGLL,TRIP13,PTPRK,PRPF19,DBN1,KRT7,TFPI,GMFB,AKAP12,PSMG1,CAV1,SOX4,MCM2,FGFR1,CHAF1A,SH3GL1,PLIN2,SMAD3,PES1,HPRT1,INSIG1,COPS5,H2AFX,ADAM9,ANXA2,TPM1,NOLC1,TROVE2,MCM6,FN1,TRIP6,HSD17B10,APRT,TGFBR2,PHLDA2,MBNL1,MTUS1,IGF2BP3,PTRF,MCM5,ATIC,COPS3,SHMT2,MFAP2,CD44,LPCAT1,CAV2,TOMM34,SLC25A1,FDFT1,MTHFD1,FADS1,APEX1,CRIM1,MYO10,FERMT2,PTPN12,CYB5B,ABCF1,ANXA1,RPA1,FDPS,SQLE,BMP4,PDLIM5 |
| 5.281e-06 | -12.15 | negative regulation of macromolecule metabolic process | biological process | GO:0010605 | 2342 | 373 | 16441 | 2138 |
MYCBP2,CHAC1,PRKCA,NUP160,UBR5,SKI,SREBF2,ZFHX3,ZFYVE28,MAD1L1,ZNF148,FNIP2,KDM5C,HRG,ZNRD1,SEH1L,HMBOX1,NR6A1,EHMT1,NFIA,CUX1,SAP30BP,SPOP,DOT1L,GZF1,DDX3X,SKIL,BRCA2,SUPT4H1,RAD18,CCNT1,SH3RF1,HIC2,TNFRSF10D,BMI1,SPOCK3,MEF2C,BANP,DROSHA,EGR1,ZHX3,KHDRBS1,SIRT7,OPHN1,PID1,RSF1,PDCD5,CDC73,ABCA7,IGF2BP3,FKBP1A,CNST,HR,MYC,IGF2BP1,PRMT5,PABPC1,TERF2,MYB,HMGCR,ADARB1,GATAD2B,ZNF675,GTF2H3,RREB1,PRDM16,ARID5B,EIF4A2,ARID1A,NELFA,PLCB1,TRIM37,ZNF425,CAT,EPRS,EHMT2,PMEPA1,CDK9,SPEN,CCDC85B,PURB,DPEP1,CNOT6,NCOR1,SMYD3,ZNF254,SPRED2,MAP2K5,BIRC6,LIN28B,PAFAH1B1,NUP43,HSPA1A,RING1,PAIP2,TERF2IP,ACD,ERI1,PPID,UCHL5,WAC,SOCS6,SERPINH1,CASP8AP2,SAP30,KMT2D,DLG4,SATB2,FGFR1,SNCA,VDR,MSX2,CDC16,SMARCC1,ELP2,DNAJA3,HIPK2,G6PD,H2AFX,TRAF3,ANXA2,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,SHQ1,TCF3,NFX1,ID2,GAS6,AKT1S1,TRIM22,MLH1,BHLHE40,NOL3,TGFB2,RNASEH2B,RPS6KA5,GIGYF2,FOXO3,PSMF1,MAD2L2,NEDD4,POM121,ABL1,SNW1,SUV39H2,TAF3,TRIAP1,CELF1,YBX3,ERRFI1,SAMD4A,SOX6,FGF9,APEX1,ZFYVE1,NXN,IL6R,UBC,POLR2A,TRIB3,KLHL22,NSD1,IREB2,ATM,BMP4,IGBP1,ANAPC4,DDIT3,KAT6A,UBN1,ATRX,NF1,PPARGC1B,POLR1A,CSNK2A1,BCOR,SIRT2,NLE1,BIRC2,SMARCB1,ANAPC1,ECM1,SRSF2,YLPM1,JAZF1,ANAPC11,ANAPC10,RELB,ZEB1,ZNF85,RAN,SLC35C2,HCFC2,OGG1,TRIM14,PTPRK,DEAF1,TRIM13,RBCK1,ATF4,AEBP2,SIRT6,BAZ2A,PPARG,TFPI,TSN,MINA,GMFB,HDAC8,BRCA1,CAV1,SOX4,ZNF91,TAF9B,UBTF,PAF1,TCF7L1,EIF4ENIF1,GATA6,SUFU,DNAJC1,CC2D1B,PER1,SOCS4,DLX2,CLU,BEND6,ZC3H8,NOCT,TNRC6A,FOXO1,PAX2,UBXN1,SMAD7,HES6,BARX2,ZIC2,DDIT4,RNF40,ELL,P3H1,MLX,MBD2,ATXN2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,NRIP1,POLR1E,PAXBP1,XPO5,WWC1,PSMA1,PRDM1,SUPT5H,HERPUD1,ISG15,UBE2E1,TCF7L2,NR2F1,MYBBP1A,SYNCRIP,IRAK2,PTRH2,ZFP90,TBL1X,PRKAR2A,TESC,AGO3,N4BP2L2,USP7,ZNF706,DLL4,ID1,ASH1L,CYLD,UPK3B,RBFOX2,SMARCA4,PBX1,RIPK1,CSTA,PIBF1,KDM1A,ZBTB21,MPHOSPH10,SOCS1,GRIN2C,NUP133,DNAJB6,IKBKB,RNF2,FHIT,PRMT3,CTC1,MOSPD1,KAT8,PRAME,PTBP2,KIRREL2,SFSWAP,POU2F1,ATXN1,ENC1,NUP214,BATF3,ZC3H12A,SMAD3,RANBP2,RBBP8,IKZF4,ADNP,SIX5,KLF4,ARNTL,ATG7,DUSP19,EIF2B3,PKIB,PARD3,DNAJC2,NIFK,SUPT6H,AGO2,H2AFJ,ATF7IP,IGF2BP2,PPP1R1C,FOXP1,BMP6,HIST2H2AB,SFI1,PTPN2,ANXA7,STC2,HIST2H3D,POLR1B,FBXO31,CD44,DMRT1,MSX1,KDM5B,CRIM1,PSPC1,FOXN3,KDM5A,DHX34,TEX14,SCMH1,HIST1H4J,PDE2A,MEN1,ZRANB3,HSPA1B,DKK1,MKX,RERE,GADD45A,TBX3,SET,MSH3,GLG1,EIF2S1,NCBP2,RBM26,RBPJ,POLR1C,NR2F2 |
| 5.440e-06 | -12.12 | CYTOPLASM | MSigDB lists | CYTOPLASM | 2079 | 332 | 17758 | 2279 |
POLB,MRPL10,TUBE1,IKBIP,AARS,PABPC4,CIAPIN1,TOM1L1,PDZD2,NEK6,PMAIP1,ATP5G2,ME1,FXN,CDK6,ACADS,AP4B1,KIF15,AKAP12,MSRB3,WDHD1,MCL1,FOXRED1,DDX3X,BRCA2,BDH2,MPV17,XPNPEP1,FIS1,NRP1,TPM1,BLMH,CARS,TNNC1,CDC42EP2,JUP,DPM3,CLINT1,PARN,NDUFS7,IGF2BP3,EIF2S2,PI4KB,COPS3,PIGG,GEMIN4,MAP3K12,LPCAT1,TOMM34,CAV2,PPA1,PABPC1,RABEPK,HMGCR,USE1,ZNF675,TIMM8B,EXOSC2,IFNGR2,RREB1,EIF4A2,PTPN12,PLCB1,CPT1A,IRS1,EPRS,MTHFD2,KPNA1,UBAP1,SRP68,D2HGDH,SURF1,PEX13,DHCR7,PDLIM5,SRP14,COG5,ABCA3,PAFAH1B1,PDK4,OLA1,MYH9,EEA1,UBL5,HSPA1A,RPGRIP1L,PAIP2,DECR1,SPG21,SOCS6,DTNBP1,NBEA,NT5C,CEP63,CMPK1,SERPINH1,PEG10,PXK,NAA35,CASP8AP2,LYST,MALL,GARS,PDK1,KRT7,MTIF2,EIF3J,LGALS1,PCMT1,PREX1,DLG4,POLG2,ERC1,SERP1,SNCA,TAMM41,CDC16,YIPF2,G6PD,DNAJA3,HIPK2,LARGE,PAM,NOLC1,XRCC4,RAB30,MAPT,BAG1,XRRA1,MRI1,TRAK1,SLC25A12,RTN4,AKT1S1,OPA1,IKBKAP,NOL3,FOXO3,MBNL1,PTRF,TRIAP1,PMPCA,SDCBP2,ANXA5,UPF2,PTGS1,DYNC2H1,ERRFI1,NT5M,PNMA1,SPTAN1,SLC40A1,APEX1,ZFYVE1,TMEM126A,LDHA,TBRG4,MRPS10,ADSL,OASL,ECH1,ANXA1,YIF1A,RARS,RETSAT,HERC1,STX18,PTPN4,SVIL,NDUFS5,APAF1,RABEP1,LETM1,TRIM16,EIF3C,NF1,RCHY1,SIRT2,RTN1,DST,ATG3,TRMU,RAN,NDUFA6,SLC27A5,YARS,HCFC2,LONP1,CARM1,TRIM14,TIMM50,SRPK2,ATF4,SESN2,ABCC4,ATOX1,ATG12,HDAC8,CAV1,KRTCAP2,SERGEF,PEX1,TIMM44,GEMIN5,CCDC3,HPRT1,EIF4ENIF1,HLCS,TP53BP1,DNAJC1,MTCH1,DCTN3,TTN,STX8,FOXO1,FN1,UBXN1,HSD17B10,MAPK8IP3,SMG7,PCSK7,XPO7,TIMM10,ETFB,DDIT4,DOPEY1,MLX,CEP290,ATXN2,VAPB,MTHFD1,NIPSNAP1,HSD17B14,VOPP1,KRT20,ELP3,BCS1L,UTP15,EIF2A,HERPUD1,APBB3,MYBBP1A,EXOC4,RRAGA,TMEM117,TESC,PDE9A,PRKAR2A,DMXL2,SART1,SUCLG1,NTSR1,GPR143,PIGH,MYO7A,SSBP2,RPAIN,GBF1,FDX1,FARSA,BRE,IDI1,SOCS1,DNAJB6,SNTG2,ETF1,CORO1A,FHIT,VCL,HTRA2,EVL,FAM172A,NARS,RAB7A,CPOX,ATXN1,VIM,CA5B,TMEM186,EIF3H,ATP5D,WARS,PLIN2,SLC30A3,TIMM17A,COPS5,ATG7,SLC25A11,SEPT5,EIF2B3,AP2S1,SMG1,DMGDH,BCKDK,SULT1C2,MAP3K13,VPS45,MAP1S,ARFIP2,APRT,IGF2BP2,WDR26,MAN1A1,MRPS11,PEX7,NDUFV1,DCTN4,PRICKLE2,SHMT2,PCK2,AMOT,SLC25A1,PPP1R9B,ABCF2,TPM4,RANGAP1,YIPF3,MEN1,RHOT2,TMEM187,SYMPK,TARS,HSPA1B,MFN2,GPC2,SERINC1,SET,GLG1,EIF2S1,ZAK,KIF1B,GCSH |
| 5.456e-06 | -12.12 | Znf_PHD | interpro domains | IPR001965 | 91 | 28 | 18293 | 2341 |
DPF3,ASH1L,PHF3,KMT2D,KDM5B,KMT2E,BAZ2A,KDM5A,DPF2,RSF1,KMT2C,CHD5,TRIM66,PHF6,MLLT10,BAZ1A,NSD1,BAZ2B,KDM2A,KDM4B,TAF3,CHD3,INTS12,KDM5C,KMT2A,FBXL19,KDM4C,KAT6A |
| 5.465e-06 | -12.12 | GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP | 190 | 47 | 17758 | 2279 |
LETM1,SMAD7,PHGDH,RPAIN,FLNB,SMARCB1,PTPN2,EIF2S2,SOCS1,IKBKB,ANAPC11,KDELC1,IPP,PAK1IP1,RNF2,ZNRD1,RBCK1,FAM172A,DDX24,TSTA3,ZC4H2,C2orf76,NOL8,SETD2,VWCE,EIF4A2,WBSCR22,LGALS1,METTL15,MEX3B,ACOXL,PHF6,ZNF622,UBAP2,MKL2,ARNTL,CEBPZ,SLC25A19,ZFP90,SENP3,TBL1X,GPAM,EIF2B3,FAM118A,DHCR7,ZNF598,SMG1 |
| 5.465e-06 | -12.12 | GSE31082_DN_VS_DP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_DP_THYMOCYTE_UP | 190 | 47 | 17758 | 2279 |
SARS,BCKDK,CUL7,RIPK1,VARS,PDCD5,HDDC2,IQGAP2,SLC30A7,NUP133,PMPCA,GPATCH1,CCDC40,POLE3,PRADC1,ERI3,LONP1,SERBP1,MBTPS2,WDR36,GTF2H3,PPAT,SIGMAR1,EIF3J,TSN,VWCE,LDHA,BMS1,METTL22,CHCHD6,FKBP3,ATP5D,KIF16B,STOML2,EPRS,TMEM237,HLCS,TRMT5,LRRC40,ADAT2,ZBTB12,SVIL,GPAM,BLMH,PDSS2,NMD3,MTCH1 |
| 5.509e-06 | -12.11 | regulation of primary metabolic process | biological process | GO:0080090 | 5688 | 831 | 16441 | 2138 |
ASCC1,THOC5,CHAC1,HLTF,CCNL2,ZNF44,ABHD6,LPAR3,NOS1AP,AMBRA1,SKI,ZNF37A,TOM1L1,NEK6,SREBF2,ZFHX3,IKZF5,PMAIP1,NSRP1,MAD1L1,WIZ,ZNF148,FNIP2,KDM5C,HRG,HMBOX1,EIF4E3,NRAS,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,C5AR1,DCUN1D5,ZNF197,STOML2,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,FIS1,DIRAS1,RUNX1,ZNF532,P2RY11,MEF2C,BANP,EPM2AIP1,TRIP6,SLK,KHDRBS1,SIRT7,PIK3R4,RSF1,CDC73,ABCA7,RBM20,CNST,UBE3A,APLF,ZNF326,MED24,ANP32B,CCDC88C,PRMT5,ZNF518B,MAP3K12,PABPC1,MYB,HMGCR,PEA15,ZNF675,GATAD2B,FADS1,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,USP10,SMARCD3,ARRDC4,MBNL2,CPT1A,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,KPNA1,GTF2A1,PDLIM1,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,SPRED2,MAP2K5,ZNF516,TRERF1,GTF2H2C,PAFAH1B1,NPAS2,PDK4,DDR2,MYH9,SAFB2,HSPA1A,ACD,ZKSCAN1,WAC,MMP14,PERP,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,PDE8B,TAF2,FBXL5,CDC16,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,AKT1S1,TRIM22,BHLHE40,TGFB2,ZNF691,PSMF1,MBNL1,TADA3,SNW1,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,SPTAN1,FGF9,USP42,NXN,IL6R,ZNF467,UBE2K,PDE3B,FOXC1,UBC,ANXA1,OXSR1,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,NLE1,BIRC2,HNRNPLL,MAP2K3,ABL2,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SLC25A23,TMPO,CDC37,PTPRK,CHD9,RBCK1,ZNF124,GCNT2,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,GMFB,SUMO3,BRCA1,ODC1,ZNF91,MLLT10,DYRK1B,HPRT1,ZNF622,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,SOCS4,TNFRSF1A,ADAM9,DLX2,BEND6,UQCC2,USP15,TTN,FOXO1,CLK1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,HES6,BARX2,ZFP36L1,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,NDRG4,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,WNT16,NT5E,CAMKK2,PAXBP1,CRADD,USP49,TLE3,SETD2,UTP15,SUPT5H,VAC14,NR2F1,TCF7L2,ATXN7,SPAG9,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,BRSK2,TESC,PRKAR2A,BCCIP,USP7,ID1,CYLD,ARID2,RBFOX2,NTSR1,PPP2R2A,RIPK1,ZNF83,SSBP2,ZNF709,PELP1,ZNF121,KDM1A,ZBTB21,NRF1,JAG1,NUP133,GRIN2C,DNAJB6,IKBKB,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,PRMT3,CASP10,CTC1,PRPF19,SEC24A,KAT8,KDM3B,PCGF3,DDX41,KIRREL2,RAB7A,C1QTNF1,AKAP13,ENC1,ZNF251,PUM3,EIF3H,USP36,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,PUS1,ZNF18,MED20,EIF2B3,ZNF589,PKIB,PARD3,ZNF507,NIFK,ESCO1,MINK1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ANKRD54,ZNF594,PTPN2,ZNF561,TMEM161A,HIST2H3D,SELT,FBXO31,CD44,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,TEX14,DHX34,HIST1H4J,PIK3CB,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,MSH3,GLG1,BCAS3,EIF2S1,USP20,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,CUL4A,PRKAB2,PRKCA,GABPB2,AARS,UBR5,LPIN1,MGA,GIPR,ZFYVE28,RNF111,CHD2,ME1,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,TCEB3,CUX1,SUPT20H,DENND4A,SON,SAP30BP,SPOP,GZF1,DOT1L,SKIL,TRRAP,CCNT1,SH3RF1,LSM14A,ARL6IP5,ZNF81,HIC2,TNFRSF10D,NRP1,BMI1,RFXAP,SPOCK3,PTPN14,WDR75,IFT57,DROSHA,EGR1,JUP,LARS2,ZHX3,ANKRD17,OPHN1,CENPB,GTF2IRD1,PID1,PDCD5,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,HR,ENTPD5,ZNF586,NOVA2,MYC,IGF2BP1,LPCAT1,CAV2,TERF2,ADARB1,SYNGAP1,RREB1,POLA1,RAP1B,ARID1A,NELFA,PLCB1,ZNF850,ARIH2,PHF6,ZNF425,CAT,ASCC3,EPRS,KIDINS220,NSF,HIF1A,PMEPA1,SPEN,MED15,ZBTB12,PURB,DPEP1,NCOR1,DHCR7,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,BIRC6,ZBTB37,FOSL2,RING1,IGSF1,PAIP2,BLOC1S2,TERF2IP,CHD7,ZNF827,SLX4,SHC1,KDM2A,PPID,UCHL5,LPIN2,SOCS6,DTNBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PDK1,MTIF2,DLG4,SATB2,MED16,PNN,SETD7,STK10,ERC1,SERP1,SNCA,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,ANXA2,SETD6,MID1,NOSTRIN,NCOR2,BRAF,TCF3,ZNF280C,NFX1,RCAN1,MYNN,MLH1,NOL3,IKBKAP,RPS6KA5,GIGYF2,PHLDA2,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,RDX,CELF1,YBX3,LARP4B,ERRFI1,MAP3K14,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,PXN,APEX1,ZFYVE1,KCNMA1,PTK2,KLF6,GUF1,POLR2A,ZFP62,KLHL22,ZNF155,IREB2,ATM,APAF1,BRWD3,DDIT3,KAT6A,STK4,ZNF76,EIF3C,UBN1,ATRX,NF1,KMT2E,PTPRA,RCHY1,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,ANAPC1,RAP1A,YLPM1,JAZF1,GPR87,ANAPC11,ANAPC10,RELB,ZEB1,PCOLCE2,HCFC2,OGG1,TRIP13,PRKACB,TRIM14,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,TNK2,TRIM13,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,TFPI,ARRDC3,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,PAF1,UBTF,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZC3H8,ZNF397,NOCT,DMTF1,MTCH1,EMSY,TNRC6A,FN1,TAF1,PAX2,DPF2,UBXN1,MED13L,RHBDD1,NAMPT,DDIT4,TOX4,RNF141,ELL,P3H1,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,HERPUD1,ISG15,UBE2E1,APBB3,MYBBP1A,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,CELSR3,CEMIP,TNXB,SMARCA4,PBX1,CSTA,PIBF1,ZSCAN5A,RRN3,MPHOSPH10,BRE,SOCS1,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,HTRA2,MOSPD1,MAML3,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,NLN,POU2F1,ATXN1,DKC1,EDEM2,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,DUSP19,SRFBP1,HEATR1,SCARB1,NFRKB,USP11,BRD9,DNAJC2,TNIK,SUPT6H,CAMK1,H2AFJ,PPHLN1,MED18,ATF7IP,IGF2BP2,PPP1R1C,SOGA1,BMP6,SFI1,PRKCH,HAS3,LDLRAD3,DMRT1,PKNOX1,RPS6KB2,KDM6B,ARNTL2,MSX1,KDM5B,FGF2,CRIM1,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,PDE2A,MEN1,EIF5B,ZNF407,SYMPK,RERE,CTIF,ZNF221,HSPA1B,ZNF708,GADD45A,CUL2,ZRANB2,NCBP2,NFKBIB,ZAK,HRH1 |
| 5.636e-06 | -12.09 | MUELLER_PLURINET | MSigDB lists | MUELLER_PLURINET | 293 | 65 | 17758 | 2279 |
BCCIP,RCHY1,PBX1,POP5,NLE1,PELP1,NOP56,ANAPC1,SRSF2,ARMC6,SOCS1,PMAIP1,PPID,TRIP13,TMPO,RFC4,MPP6,RFC3,GNL3,PNN,MCM2,POLG2,FKBP3,CHAF1A,CXADR,EXO1,HPRT1,SMARCC1,LUC7L3,ARL4A,CEBPZ,ANXA2,COPS6,NOLC1,MUTYH,MCM10,MCM6,PHGDH,DCTPP1,MYC,MBD2,COPS3,ATIC,MCM5,PRMT5,FBL,MTHFD1,MYB,PXN,APEX1,SMARCAD1,NOP58,RPA1,POP1,TOE1,MYBBP1A,NME1-NME2,GADD45A,SYNCRIP,ARID3B,SET,MSH3,NFKBIB,WDR33,POLR1C |
| 5.775e-06 | -12.06 | nucleolar part | cellular component | GO:0044452 | 59 | 21 | 17570 | 2233 |
SNU13,POLR1A,SIRT7,UTP15,NOL6,POP5,DKC1,NOP58,NOP56,PES1,RPP30,POP1,UBTF,MPHOSPH10,HEATR1,POLR1B,POLR1C,FBL,ZNRD1,UTP4,POLR1E |
| 5.858e-06 | -12.05 | CTTTGT_V$LEF1_Q2 | MSigDB lists | CTTTGT_V$LEF1_Q2 | 1862 | 301 | 17758 | 2279 |
PTP4A1,ADAM19,TNFRSF21,TMEM109,CCNL2,GABPB2,PCDH7,SREBF2,ZFHX3,PAK1IP1,CHD2,CDK6,PPM1K,ZNF646,HMBOX1,NRAS,RNMT,NR6A1,ENHO,EYA3,AP4B1,AKAP12,SEMA3F,ZDHHC14,SPOP,SKIL,CCNT1,LUC7L3,TMEM139,HIC2,GREB1L,TPM1,BMI1,ZNF532,MEF2C,EFNB2,TNNC1,KHDRBS1,ST6GAL1,DLGAP4,OPHN1,BTBD9,MTUS1,FAM192A,RSPRY1,TECTA,HR,SLC7A11,TSPAN2,MFAP2,IGF2BP1,CNOT4,ANGPT2,MYB,LRRC20,BDNF,COL17A1,STAG1,MYO10,RB1CC1,EPS15L1,RAP1B,PTPN12,ARID1A,ONECUT2,MBNL2,SEC31A,DYNC1H1,PDLIM1,ZZEF1,VCAN,ZBTB12,PEX13,AMOTL1,ACTR3,HFM1,CD99L2,PTPRG,PAIP2,PHC2,ZNF827,CD96,MMP14,SHF,INTS12,CMPK1,TMEM136,CDK12,SAP30,ATP6V0A1,PNN,GALK2,MARCH6,MEF2D,GSTCD,TTC28,TBC1D16,ERC1,STK10,MAT2A,DHX57,BAZ1A,SMARCC1,ASTN2,MBTD1,HOXA3,MID1,RAB30,MAPT,HMGA2,SSH2,BRAF,SCAMP3,SESTD1,ZNF280C,RTN4,IP6K2,DNAJC22,TGFB2,FOXO3,RSRC1,NEDD4,ABL1,NISCH,CELF1,MAP3K14,C15orf41,SOX6,HNRNPM,NAV3,FGF9,VPS37A,APEX1,ZFYVE1,AGPAT4,NXN,PACS1,UBE2K,POLR2A,NSD1,IREB2,HERC1,HNRNPH3,RNF138,PTPN4,SLCO5A1,SVIL,KAT6A,FEM1C,ATRX,KIF5A,RNF43,SLC30A7,RTN1,DST,SRSF2,PHF5A,XRCC2,TRIML2,JOSD1,KIAA0922,ETV1,ZNF3,LAMA4,ZBTB17,GPM6A,ATF4,GCNT2,MIOS,TXLNG,SKAP2,CMIP,SLC38A1,BAZ2A,ANK2,KATNAL1,GDPD1,ARRDC3,MED27,ZSCAN2,KRTCAP2,ODC1,YTHDF2,CDHR3,UBTF,TCF7L1,SUFU,ARL4A,CSMD3,MAGI1,TNRC6A,DCTN3,PGPEP1,TAF1,RHOBTB1,STXBP6,PAX2,DPF2,HES6,ZFP36L1,XPO7,DDIT4,DOPEY1,PDE10A,VPS72,BUD31,CTR9,AKAP11,LRP3,NIPSNAP1,MSI2,CRADD,USP49,TRA2A,TLE3,JMJD1C,SETD2,TBXAS1,MEX3B,MAPK1IP1L,HERPUD1,EXOC6,SPAG9,SYNCRIP,SDCCAG8,TBPL1,SLC16A1,ARHGAP12,BRSK2,FNBP1L,TCF12,MMRN2,RBFOX2,SMARCA4,RNF24,SPATS2,SEMA6A,BRE,CCDC50,SLC38A2,MET,AHCYL1,IPO11,MOSPD1,HN1,SOBP,KDM3B,RTN4RL2,PTBP2,TUBA1A,TFCP2,C1QTNF1,NLN,VIM,ARL5B,RAB10,RAD54B,SMAD3,LMBR1L,IKZF4,SIX5,ADNP,HNRNPR,ITGA2,INTS9,FKBP5,TSPAN5,ATXN7L2,KLHL24,MAP3K13,CMTM8,ARFIP2,FOXP1,BZW2,IL17RE,DSG2,STC2,PRICKLE2,DDX31,FBXO31,TOP1,PPP1R9B,MSX1,CRIM1,MON1A,TEAD1,SMARCAD1,FOXN3,ANKMY2,NAALADL2,DKK1,RERE,GADD45A,SET,ZNF32,RBPJ,NR2F2,ZAK,MMP16,KIF1B,C6orf223 |
| 5.910e-06 | -12.04 | PROVENZANI_METASTASIS_UP | MSigDB lists | PROVENZANI_METASTASIS_UP | 185 | 46 | 17758 | 2279 |
EFNB2,CARS,TCF12,CUL4A,DROSHA,TCF3,DDX19A,VARS,HLTF,AARS,TERF2IP,MCAM,ACD,ATP5G2,FGGY,KDELC1,SLC38A2,MRPS27,MET,LARP4B,PEG10,VCL,ATP6V0D1,PPA1,TERF2,MYB,ITPA,PCCA,VSNL1,MARCKSL1,SLC35D1,SYT1,TARS,POLR2A,PLIN2,CAT,EPRS,TSR1,DDX50,GLG1,CDKAL1,ADK,TESC,BAG1,KDM4C,GCSH |
| 5.935e-06 | -12.03 | Znf_PHD-finger | interpro domains | IPR019787 | 77 | 25 | 18293 | 2341 |
DPF3,PHF3,KMT2D,KDM5B,KMT2E,BAZ2A,KDM5A,DPF2,NFX1,RSF1,KMT2C,CHD5,TRIM66,MLLT10,BAZ1A,NSD1,BAZ2B,KDM2A,TAF3,CHD3,INTS12,KDM5C,FBXL19,KMT2A,KAT6A |
| 5.981e-06 | -12.03 | anion binding | molecular function | GO:0043168 | 2626 | 416 | 16491 | 2164 |
ARHGAP26,ACTG1,DDX19A,AARS2,NAT10,TUBE1,SBF2,HLTF,NBEAL1,PRKCA,RAC3,LPAR3,AARS,EXOC1,MMP7,NEK6,ZFYVE28,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,HRG,CDK6,ACADS,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,OSBPL1A,STOML2,GNAI1,DDX3X,DDAH2,DNAH2,RIOK1,DIRAS1,RUNX1,NRP1,CARS,ADGRE2,EP400,LARS2,SLK,TRIO,SIRT7,AK6,OPHN1,PIK3R4,TGFBR2,PDCD5,CHD5,SLC1A1,YARS2,ANXA10,ABCA7,SH2B3,PRKCE,DDX56,PI4KB,DHX37,ASAP1,MCM5,MAP3K12,PRPS1,HMGCR,SIK3,DDX28,MYO10,PCCA,EIF4A2,RAPGEF4,IDH3G,TYW1,RAP1B,PLCB1,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,MTHFD2,NME7,ALKBH3,NSF,TRAP1,FGFBP1,CDK9,D2HGDH,RIOK3,GPN1,SQLE,DPEP1,MAP2K4,SDSL,DNM3,MAP2K5,ABCA3,SYT17,DDX18,PAFAH1B1,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,EEA1,CBWD5,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,DECR1,PRKD3,ASNS,SHC1,ABCA12,CLCN6,NBEA,MSH4,CMPK1,PXK,PLEKHA4,CDK12,LYST,PMS1,RFC4,ZCCHC14,GARS,PDK1,MTIF2,PREX1,GNL1,GALK2,STK10,MAT2A,FGFR1,DHX57,SNCA,VDR,CAMK2D,HIPK2,PEMT,DNAJA3,ARL13B,PAM,CBWD1,RPS6KB1,MDN1,ANXA2,NOLC1,RAB30,VWA8,FGFBP3,BRAF,SESTD1,C10orf2,FARS2,KIF5C,GAS6,IP6K2,MLH1,OPA1,RPS6KA5,NEDD4,TTLL11,ABL1,FTCDNL1,CBWD6,GATC,NISCH,ANXA5,PHYKPL,HARS2,DYNC2H1,MAP3K14,ACTR3B,CLK2,NAV3,PFKFB4,FGF9,TTLL5,DDX24,WDFY3,ZFYVE1,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,ANXA1,OXSR1,TRIB3,ETFDH,SRCAP,RARS,DDX50,HELZ,ACOX1,ORC5,ATM,APAF1,BMP4,ADK,STK4,MVK,ATRX,NF1,RARS2,KIF5A,MFGE8,TRPM6,CSNK2A1,PLOD1,SIRT2,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,PCOLCE2,RAN,SLC27A5,YARS,LONP1,TRIP13,PRKACB,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,SIRT6,PPARG,HARS,KATNAL1,CDK4,HSPA5,COL4A3BP,KSR2,MTHFD1L,SGK2,LSG1,MGST1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,C2CD5,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,FN1,CLK1,RHOBTB1,TAF1,STXBP6,DNAH1,P3H1,ABCA5,PDE10A,ALDH18A1,GMDS,N4BP2,SNX29,MTHFD1,WARS2,CAMKK2,PDE4A,BCS1L,LIG4,OBSCN,SYT1,AGAP1,ACOXL,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,SNX24,RRAGA,HK2,HMBS,DDX10,TBCK,BRSK2,SH3PXD2A,PRKAR2A,SNX27,CHMP2A,SUCLG1,PAPD4,MYO7A,GPR143,TNXB,SMARCA4,RIPK1,DHX35,GBF1,DDX60L,KDM1A,MIEF1,RIOK2,CAD,FARSA,DUS4L,UBR1,NVL,CBR4,RPS6KL1,IKBKB,MYH15,MET,TMLHE,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,ATP8B2,ARL5B,RAB10,ATP5D,WARS,TPK1,RAD54B,DUS3L,SCARB1,SEPT5,SMG1,PARD3,BCKDK,TNIK,MINK1,DNAJA4,MAP3K13,ARL15,CAMK1,PDE4B,TKFC,ARFIP2,APRT,VARS,CSNK1A1,PIP4K2A,MFHAS1,GFM2,IQGAP2,PRKCH,ADH5,NDUFV1,GART,ANXA7,SHMT2,DDX31,PCK2,MICAL3,HSD17B12,PCSK6,RPS6KB2,GPHN,FGF2,SMARCAD1,ABCF2,DHX34,TEX14,FERMT2,MARS,ARHGAP32,PDE2A,GPNMB,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,MFN2,HSPA1B,GPC2,WDR35,MSH3,NR2F2,RPS6KC1,KIF1B,ZAK |
| 6.036e-06 | -12.02 | cellular process | biological process | GO:0009987 | 14182 | 1908 | 16441 | 2138 |
PTP4A1,ARHGAP26,GGT1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,MKS1,TUBE1,SBF2,CCNL2,ZNF44,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,MMP7,IKZF5,ZFHX3,ATP5G2,AP1M1,MAD1L1,KDM5C,SRRM2,ZNRD1,FTSJ3,PPM1K,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,UPP1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,RBSN,SSU72,RAD18,BDH2,MPV17,RIOK1,DIRAS1,RUNX1,TPM1,SLC25A26,ZNF532,P2RY11,BANP,TMEM63C,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,CHN1,RBM20,UBE3A,DHX37,APLF,WDR60,MED24,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,ANGPT2,MYB,NOM1,RABEPK,KLRD1,ZNF675,GATAD2B,IFRD1,ALG6,WDR61,STAG1,KCNQ3,ZNF587,ARID5B,IDH3G,TYW1,ATAT1,USP10,ST6GALNAC3,MAP7D1,SNAP25,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,RPL28,EHMT2,TRAP1,FGFBP1,CCDC85B,KIAA0196,BPNT1,PDLIM5,ARHGAP10,SRP14,C18orf25,SGSM3,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,VTI1A,DDR2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,UBL5,RPGRIP1L,NDUFB3,ESAM,SPG21,ZSWIM7,ACD,WAC,CLCN6,MMP14,INTS12,MSH4,PEG10,PXK,MGLL,TRMT12,ZC3H3,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,SLCO6A1,CCNDBP1,KCNH3,MEF2D,SLC35D1,DSP,NUDT15,MAT2A,FBXL5,SLC39A14,ARHGAP21,KDM4B,ELP2,MISP,NSMCE2,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CATSPERG,METTL2B,RAB30,BAG1,MAPT,MORC2,COMMD10,HMGA2,SHQ1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,PTGS1,ZNF710,FBXL19,ACTR3B,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,USP42,LDHA,NXN,CCDC113,PPIP5K2,UBC,ANXA1,MRPL36,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,UQCC1,MTMR1,CYP24A1,CUL7,TRIM16,SLC25A21,FAM13A,NLE1,SCAF8,HNRNPLL,MAP2K3,AMPD3,ECM1,SRSF2,PHF5A,COPS4,NCKIPSD,HKR1,TRIML2,ZNF3,ZMYM2,SLC25A23,DBN1,FMNL3,RBCK1,AEBP2,ATF4,MIOS,PPARG,CDK4,ANK2,ATOX1,HSPA5,TSN,PSMG1,SUMO3,LAMA2,KCNH2,ODC1,DLST,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,UQCC2,USP15,CTU2,FOXO1,CLK1,PRSS3,NKD2,MAPK8IP3,FAN1,SMAD7,LAMTOR3,ZIC2,ARID1B,SPIRE1,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,ICE2,WNT16,PNPLA3,LRSAM1,WARS2,USP49,IFT43,HAUS6,SETD2,OBSCN,ACOXL,TCF7L2,PRPF40B,GRIK4,CASS4,SIL1,DTD1,GGT7,PTP4A2,DDX10,SLC52A2,SH3PXD2A,BCCIP,USP7,SART1,MPI,ID1,OLFM2,SUCLG1,PAPD4,ARID2,NDUFAF2,NTSR1,RPS29,SLC2A1,LAGE3,RIPK1,DENND3,TNKS1BP1,RADIL,PAG1,PPP1R9A,SEMA6A,ZNF121,PLXNB1,FDX1,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,CCDC40,BCAP29,AHCYL1,SPIDR,PRPF19,KDM3B,ARHGAP17,TEX19,RAB7A,VIM,CA5B,ZNF251,EIF3H,TJAP1,EXO1,IFT81,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,NIFK,ESCO1,MINK1,KIZ,MCM10,AUH,HM13,RFX1,AGO2,APRT,VARS,FOXP1,POGZ,HIST2H2AB,SLC25A20,ADH5,TTC1,TMEM161A,CPNE7,POLR1B,SNAPC5,PCSK6,TRNP1,AP4S1,MON1A,FOXN3,SMARCAD1,SLC35G1,TOP3A,FERMT2,RANGAP1,ARHGEF12,YIPF3,EXOG,PALLD,POLR3A,SMPDL3B,DKK1,CDH24,CACNB1,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,ZNF32,RBPJ,TAF12,NR2F2,KIF1B,ZNF292,CUL4A,PRKCSH,GYG1,PRKCA,LRP5L,GABPB2,LPIN1,EXOC1,S100A10,SUCLG2,DPH6,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,CAMSAP2,EFHC1,SUPT20H,HIST1H2BL,ZDHHC14,SON,DENND4A,CLNS1A,PLCXD2,SPOP,DOT1L,GNAI1,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,SH3RF1,NSMCE1,ARL6IP5,LUC7L3,CFD,HIC2,XPNPEP1,NRP1,TNFRSF10D,BMI1,BLMH,SPOCK2,ZMAT3,SPOCK3,CADM4,PRPF38B,CDC42EP2,JUP,PRPF31,LARS2,ST6GAL1,TATDN3,DPM3,SSR4,PRPF39,PDCD5,NDUFS7,HR,SLC7A11,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,FDFT1,EXOSC2,IFNGR2,ANAPC13,PRIM2,RREB1,PCCA,RDH10,RAPGEF4,RAP1GAP2,RAP1B,ARID1A,NELFA,TPRA1,SLC26A11,MTR,ZNF850,ANGPTL4,PHF6,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,ZCCHC6,SQLE,DPEP1,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,ZNF254,SYT17,BIRC6,UROD,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,RING1,FLNB,IGSF1,NOP56,BLOC1S2,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,RMDN3,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,PREX1,PCMT1,LRRC8A,GNL1,SATB2,MARCH6,SETD7,ERC1,SERP1,HSD3B7,SNCA,ZBTB25,BAZ1A,DNTTIP1,MSX2,CAMK2D,SMARCC1,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,TRAF3,TBXA2R,XRCC4,SETD6,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,OPA1,RPS6KA5,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,NEBL,ELP5,SDCBP2,CELF1,DYNC2H1,S100A14,ERRFI1,CLK2,FER1L5,SLC40A1,PXN,TTLL5,APEX1,PSAT1,AGPAT4,ADSL,PACS1,BMS1,GUF1,KLF6,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,SVIL,ATM,NDUFS5,APAF1,ADK,DDIT3,IPO4,KAT6A,IMMP2L,ZNF76,PIGM,LETM1,EIF3C,KMT2E,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,KANSL1,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,SRPK2,DEAF1,TNK2,SESN2,FBXW4,ZNF195,SKAP2,SIRT6,ITPA,MINA,TMEM216,KSR2,MTHFD1L,PITPNB,SGK2,KMT2C,ST3GAL5,MPC1,ARPC3,TIMM44,EIF4ENIF1,HLCS,CC2D1B,CTAGE5,CRCP,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,FBXO45,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,SMG7,EVPL,TIMM10,NAMPT,RNF141,ELL,P3H1,HVCN1,ZNF354A,ISPD,TENM3,CCDC124,PRF1,ATP6V0D1,AKAP11,MTHFD1,ZNF629,MSI2,ZNF234,PPAT,ELOVL6,TRA2A,XPO5,JMJD1C,ELP3,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,BICD1,FSCN1,FAT1,FDPS,SLC16A1,CDKAL1,TBL1X,PFDN2,IFITM2,TBCK,FNBP1L,PDE9A,AGO3,NR2C2AP,TCF12,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,ARSJ,PIBF1,DHX35,SBDS,RIOK2,RRN3,KCTD11,MPHOSPH10,SOCS1,CBR4,FHIT,ADCK4,ITGAX,VCL,TMEM120B,UTP4,GNG5,AUP1,MAML3,NARS2,NPW,RTN4RL2,PRAME,METTL2A,GRHL3,MRRF,ANKDD1B,METTL15,ATXN1,POU2F1,EDEM2,DKC1,UBR4,BATF3,ARMC4,ALAD,DUS3L,KPNA3,IKZF4,HNRNPR,ZNF557,ARNTL,CEBPZ,DUSP19,FKBP5,TMEM101,NFRKB,RNF130,ARC,BRD9,SMG1,TMEM33,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,PDE4B,VPS45,MED18,CHCHD10,ATF7IP,SEMA3E,SOGA1,PIP4K2A,BMP6,MFHAS1,GFM2,PEX7,SCN1B,SEC24C,STC2,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,ARNTL2,SLC6A16,PPP1R9B,DNMBP,KDM5B,GPHN,FGF2,CRIM1,ZNF821,KDM5A,PSPC1,SULT4A1,SCFD2,ASAP3,ZNF324B,SCMH1,PDE2A,PEAK1,EIF5B,CTIF,ZNF221,SERINC1,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,ZSWIM6,ASCC1,GNB3,WDR74,CACNA1H,CHAC1,HLTF,NT5C3A,COA1,NUP160,SYNJ1,AMBRA1,PABPC4,TOM1L1,NEK6,SREBF2,PMAIP1,NSRP1,SYN2,RASSF3,FAAH2,PDS5B,WIZ,FNIP2,ZNF148,HRG,FXN,AVEN,CDK6,WLS,PTPRM,RFX2,MSRB3,AKAP12,MCL1,PLEKHM3,DCUN1D5,RBM28,SLC50A1,TMSB4X,STOML2,DDX3X,ZNF266,BRCA2,SUPT4H1,FIS1,FIP1L1,RBP1,MEF2C,CARS,ADGRE2,TNNC1,HERC2,EP400,CLDN15,TRIP6,SLK,KHDRBS1,SIRT7,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,ANP32B,NOC3L,PRMT5,ZNF518B,MAP3K12,AGL,COQ3,FMNL2,TOMM34,HMGCR,FADS1,PEA15,TIMM8B,GTF2H3,BDNF,COL17A1,MYO10,RB1CC1,TSPYL4,PRDM16,STPG1,EPS15L1,EIF4A2,ZNF512B,RYR2,SMARCD3,IMPDH2,EVI5,CPT1A,MBNL2,ONECUT2,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,GTF2A1,CLASRP,LEMD3,CDK9,SURF1,ZNF160,ADGRE5,SENP3,CNOT6,WDR33,DNM3,ABCA3,MAP2K5,ZNF516,TRERF1,DDX18,ATP6V1A,NPAS2,PDK4,ACTR3,MYH9,TUBB6,SAFB2,STAM,EEA1,HSPA1A,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,NT5C,CEP63,MTHFD2L,LSM10,PERP,GARS,KRT7,STAMBP,NPM3,ASUN,ATF7IP2,LGALS1,ARHGEF10,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,PES1,GNG2,TAF2,HLA-DMA,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,BRCC3,ZBTB11,YEATS2,ANKS1A,LAMA5,TRIM36,SERINC5,ZNF786,INSIG2,XPC,TRAK1,SF3A3,ID2,JMJD6,AKT1S1,BHLHE40,TGFB2,RSRC1,MBNL1,POM121,TADA3,NPRL2,SUV39H2,GATC,TMSB10,PVRL3,ARHGAP1,SOX6,HNRNPM,LYPLA2,DIS3L2,ULBP1,NUDC,DDHD1,FGF9,CEP83,POLK,ARHGAP39,MRPS10,IL6R,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,KISS1R,RPA1,TRIB3,TOE1,ETFDH,RARS,BAZ2B,PXDN,POLE2,PLPPR2,STX1A,ARID3B,SLC25A19,SLCO5A1,PTPN4,GPAM,PSAP,IGBP1,DOCK6,ANAPC4,CORO2B,KDM4C,SRM,GPBP1L1,PPARGC1B,TFIP11,POLR1A,MFGE8,HECTD3,NREP,CSNK2A1,RNF43,COX10,SEC16A,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,FLNC,METTL1,CHD9,GCNT2,ZNF124,SLC3A2,ABCC4,SKIV2L2,HARS,ZNF414,BAZ2A,KATNAL1,MED27,NOL6,COL4A3BP,GMFB,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,MSRA,ZNF622,TOM1L2,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,RAD51B,DLX2,C2CD5,CHMP4C,SEPHS2,XYLB,SARS,TTN,AOC3,MCM6,STX8,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,RNF40,ABCA5,TRMT13,PDE10A,PPIL2,GTF2H1,TIMELESS,SYNJ2,ALDH18A1,GMDS,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,PAXBP1,TLE3,HOMER2,UTP15,BCS1L,RNH1,MEX3B,TRAPPC6B,SUPT5H,VAC14,NR2F1,PGD,NAP1L5,PWP1,ATXN7,FAM135A,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,DNAH17,TBPL1,ZNF430,PPP1R12B,ARHGAP12,HMBS,BRSK2,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,RBFOX2,LPCAT2,GPR143,PPP2R2A,RSL1D1,ZNF83,RNF24,LPCAT3,ZNF709,PELP1,RPAIN,KDM1A,DENR,METTL16,CAD,ZBTB21,DUS4L,UBR1,DNAJB6,IKBKB,ZDHHC6,HIRIP3,ANO8,RNF2,ETF1,ZFP37,HIBCH,CORO1A,PRMT3,CASP10,CTC1,SKIV2L,SEC24A,KAT8,WDR36,PCGF3,EVL,TUBA1A,DDX41,NARS,THSD4,C1QTNF1,CPOX,TMEM123,AKAP13,ENC1,ARL5B,NUP214,USP36,ATP5D,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,TIMM17A,ZNF333,ABHD3,ITGA2,ZNF436,PUS1,NFASC,ZNF18,SEPT5,AP2S1,PPIL3,UNC13D,MAP3K13,ARFIP2,MAP1S,ZNF346,CSNK1A1,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,SACS,NDUFV1,ANXA7,ZNF561,CWC27,IFIT5,PRICKLE2,HIST2H3D,DDX31,SELT,FBXO31,CD44,HSD17B12,GINS3,ZNF654,ZMYM5,TPM4,DHX34,TEX14,PEAR1,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,PIK3CB,TMEM175,CHCHD6,NEU1,ZRANB3,MKX,POLR3G,CENPP,TMEM237,SRBD1,GPC2,ZBTB8OS,ADAT2,SET,MSH3,GLG1,EIF2S1,NDUFAF5,MYRF,ITGB4,RPS6KC1,GCSH,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,DDX19A,PLRG1,TMEM109,ENAH,RAC3,AARS,UBR5,MGA,GIPR,RPS16,RNF111,VPS52,ME1,CEP135,MEIS3,TRMT10A,FUT11,SEH1L,DPF3,SLC38A6,SNU13,SETD1B,ATG9A,NR6A1,ALDH1L2,NOL8,GNG7,EYA3,TCEB3,CUX1,HSH2D,SEMA3F,FOXRED1,SAP30BP,SH3GL1,SKIL,ZNF81,VPS13D,DNAH2,SEMA3C,CCNB1IP1,TXN2,PTPN14,EFNB2,WDR75,IFT57,DROSHA,EGR1,CELSR1,ANKRD17,ZHX3,AK6,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CHD5,CD226,IGF2BP3,PRKCE,FKBP1A,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,SCAF11,ADARB1,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,POLA1,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,ZNF425,DAGLA,EPRS,KIDINS220,NSF,UBAP1,PMEPA1,ZBTB12,D2HGDH,RIOK3,PURB,PEX13,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,RTTN,PPDPF,PTCD2,AMOTL1,TRPM2,LIN28B,ZBTB37,HFM1,NDUFB5,C1QTNF7,OLA1,KLHL18,FOSL2,SLC25A44,AP1B1,LTB4R,PDE3A,PHC2,TERF2IP,CHD7,FLAD1,ZNF827,PUS3,SHC1,KDM2A,UCHL5,VGF,SSBP1,SERPINH1,KMT2A,ATP6AP1L,RFC4,MPP6,CFAP221,RFC3,PDK1,MTIF2,SFXN4,WDPCP,DLG4,MED16,GALK2,PNN,POLG2,STK10,DHX57,DCBLD2,TAMM41,VDR,HTR7,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,MDN1,ANXA2,PDCD11,NOLC1,TROVE2,NCOR2,UTP14A,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,MYNN,RTN4,MLH1,CEP126,LIAS,MON2,IKBKAP,NOL3,GDPD5,FOXO3,MAD2L2,NEDD4,DCTPP1,ZNF239,ZNF483,COMMD9,PTRF,NISCH,TRIAP1,PMPCA,PHYKPL,HARS2,UPF2,RDX,COPS7B,NLGN3,EXOSC4,YBX3,MAP3K14,NT5M,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,TBRG4,PTK2,APTX,CAAP1,OASL,MMAA,NOP58,ECH1,POLR2A,YIF1A,FBXO21,KLHL22,ZDHHC11,COL26A1,HNRNPH3,STX18,RNF138,PGAM5,BRWD3,RABEP1,LRRC41,SLC43A1,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,CERS5,FANCD2,TRPM6,RCHY1,PLOD1,ZNF107,BCOR,SLC29A1,SIRT2,STK33,SNAPC4,CUTC,AHCYL2,WNT2B,EDC3,MRPS30,SMARCB1,RTN1,SRPRB,ANAPC1,RAP1A,YLPM1,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,POLR3B,NDUFA6,SLC27A5,GALNT18,OGG1,LONP1,TRIP13,PRKACB,TIMM50,ELOF1,LAMA4,ZBTB17,TRIM13,GPM6A,TXLNG,SLC38A1,ZNF680,GPCPD1,HDAC8,CAV1,ZSCAN2,SOX4,TCTN1,SERGEF,CHAF1A,CDHR3,TAF9B,PAF1,GEMIN5,RHOU,UBTF,EPN2,UBE3D,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,BBIP1,ABCC3,GALNT10,ZNF397,COPS6,NOCT,DMTF1,EMSY,TNRC6A,VIPR1,SLC12A7,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,PAX2,DPF2,GPAT3,CDIP1,ALG8,MED13L,PHGDH,ADGRG6,RHBDD1,ETFB,DDIT4,TOX4,CEP164,SIPA1L3,ATXN2,BANF1,BUD31,SEMA3D,GLTP,NRIP1,N4BP2,POLR1E,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,PSMA1,WWC1,PRDM1,TMEM241,BLOC1S4,C19orf70,DNAH14,ISG15,MYBBP1A,ATAD5,INTS5,SDCCAG8,RRAGA,HK2,EXOC4,PTRH2,ZFP90,PDSS2,ZBTB24,ASH1L,PCNT,SLC5A5,CELSR3,MYO7A,SLC9B2,CSTA,PUDP,GBF1,SLC39A1,ZSCAN5A,MIEF1,VPS18,FARSA,BRE,CAMTA2,LYPLAL1,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,TSPAN14,TMEM14C,HTRA2,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,PTBP2,TFCP2,PARP2,SFSWAP,NLN,TOR1AIP2,ATP8B2,RAB10,PUSL1,WARS,TPK1,RAD54B,ZC3H12A,PLIN2,HYAL3,ADNP,COPS5,SRFBP1,SCARB1,HEATR1,DISP1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,SH2D3A,SULT1C2,H2AFJ,DBF4,TKFC,PPHLN1,PPP1R1C,MFSD10,SFI1,MAN1A1,MRPS11,PRKCH,IL17RE,GART,CTNNBL1,HAS3,TANK,DSG2,KDELC1,SHMT2,TTC17,UTS2,AMOT,DMRT1,SLC25A1,MSX1,IL11RA,TEAD1,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,SYMPK,NAPEPLD,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,MPP7,CUL2,ZRANB2,NCBP2,TATDN1,ZAK,MMP16,SLC16A10,ARHGAP27,HRH1 |
| 6.235e-06 | -11.99 | SCHUHMACHER_MYC_TARGETS_UP | MSigDB lists | SCHUHMACHER_MYC_TARGETS_UP | 77 | 25 | 17758 | 2279 |
SRM,EXOSC2,AUH,PPAT,CDK4,LDHA,VARS,IMPDH2,ODC1,MGST1,NAMPT,PYCR1,ZNF239,CAD,SLC39A14,TRAP1,MYC,CEBPZ,SLC16A1,NOLC1,FXN,DDX10,GCSH,RABEPK,MTHFD1 |
| 6.251e-06 | -11.98 | TTTGCAG,MIR-518A-2 | MSigDB lists | TTTGCAG,MIR-518A-2 | 202 | 49 | 17758 | 2279 |
TCF12,HMGA2,RBM33,ANKRD17,PRKAB2,ACTR3,NHS,MED13L,ZFP36L1,WDR26,MAN1A1,NRF1,JAG1,NCKIPSD,ETF1,IGF2BP1,TSPAN14,SAMD4A,SEH1L,SRPK2,DSC3,CHD9,AEBP2,KDM5B,LAMC1,EIF3J,ANK2,ARRDC3,R3HDM1,SATB2,PNN,PLCB1,PHF6,BTBD11,FBXL5,UBAP2,KPNA3,GADD45A,PMEPA1,HNRNPR,LEMD3,CUL2,SET,TAF4,PURB,NCOR1,SLC25A26,C18orf25,DCAF5 |
| 6.326e-06 | -11.97 | MYC (v-myc avian myelocytomatosis viral oncogene homolog) | protein interactions | 4609 | 595 | 123 | 16036 | 2270 |
TCF12,MYCBP2,NDUFA5,CUL4A,SUCLG1,ACTG1,HECTD3,FANCD2,CSNK2A1,SMARCA4,ZNF121,HSPA1A,KDM1A,MAP2K3,NOP56,SMARCB1,RPP30,PDZD2,PMAIP1,NUP133,DNAJB6,SSBP1,SERPINH1,CDK6,CDK12,TRIP13,LONP1,CARM1,TMPO,ZBTB17,PHLDB2,RFC4,RFC3,BRD4,PDK1,TUBA1A,AKAP8L,CDK4,TSN,LGALS1,MINA,MCL1,MED16,BRCA1,HIST1H2BL,ERC1,USP36,ATP5D,SMAD3,PES1,VDR,RANBP2,MIR17HG,CAMK2D,TRRAP,EIF4ENIF1,SMARCC1,ADNP,CCNT1,E2F4,DNAJA3,SLC25A11,RNF130,RUNX1,HEATR1,ANXA2,SLC25A26,PTPN14,EP400,SARS,FN1,MAP3K13,TTC27,SMAD7,SLC25A12,IGF2BP2,MLH1,OPA1,SSR4,IKBKAP,FOXP1,FOXO3,IQGAP2,IGF2BP3,TADA3,SNW1,P3H1,PI4KB,PTRF,MYC,GTF3C3,GEMIN4,IGF2BP1,ALDH18A1,FBL,SLC25A1,TOP1,CRADD,KDM5B,DDX24,POLA1,XPO5,IDH3G,PSMA1,RNH1,MARS,MEN1,ANGPTL4,POLR2A,DYNC1H1,RARS,SPAG9,MYBBP1A,HELZ,KIDINS220,HIF1A,CDK9,EXOC4,MSH3,RBPJ,TAF12,PTP4A2,IPO4 |
| 6.360e-06 | -11.97 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDM_UP | 191 | 47 | 17758 | 2279 |
CYP24A1,PTCD2,IFT57,SIRT7,HES6,CD99L2,TUBB6,XPO7,ETFB,LPIN1,MAP2K3,PAIP2,ABL1,PHF5A,SCN1B,MYC,NCKIPSD,PPCDC,UBAP2L,KDM5C,ITGAX,VCL,DMRT1,NUDC,HMGCR,FDFT1,ATF4,RDH10,TTYH2,GALK2,MARCH6,IMPDH2,EVI5,USP36,SLC23A2,RPA1,PWP1,LSS,TMCO1,EIF4ENIF1,CEBPZ,H2AFX,SQLE,NOLC1,FAM118A,DHCR7,ZNF598 |
| 6.380e-06 | -11.96 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN | 180 | 45 | 17758 | 2279 |
SRM,CARS,PIGM,CHST11,URB2,B4GALT5,TUBE1,TMEM177,ISG20L2,SLC29A1,AARS,UBL5,YARS2,MAP2K3,POLR3D,RAP1A,PUS3,ASNS,ATXN2,PYCRL,LPIN2,WIZ,PRADC1,FTSJ3,PKNOX1,LYST,TIMM50,NT5E,ZNF234,WDR36,TMEM126B,MRRF,RBM28,SLC26A11,TAF9B,GEMIN5,SLC7A1,POP1,GLS,RBBP8,TRAP1,DNAJA3,CENPBD1,DDX10,GPATCH4 |
| 6.628e-06 | -11.92 | NUCLEOPLASM_PART | MSigDB lists | NUCLEOPLASM_PART | 208 | 50 | 17758 | 2279 |
TAF1,NPAS2,PRPF31,PPARGC1B,TFIP11,HES6,MED18,RSF1,IKBKAP,SNAPC4,RPAIN,ARID1B,SMARCB1,SUB1,SRSF2,INTS7,NSRP1,JAZF1,GTF2H1,INTS12,ZNF148,GTF3C3,CPSF3L,TIMM50,SAP30,SCAF11,NR6A1,ELP3,ATXN1,HDAC8,MED16,ARID1A,MEN1,POLR2A,CHAF1A,POLR3G,RPA1,GEMIN5,TAF2,TRRAP,SMARCC1,ELP2,HIF1A,INTS5,CDK9,HIPK2,TAF4,ARNTL,INTS9,TAF12 |
| 6.746e-06 | -11.91 | AMIT_EGF_RESPONSE_240_HELA | MSigDB lists | AMIT_EGF_RESPONSE_240_HELA | 59 | 21 | 17758 | 2279 |
SPRED2,DNMBP,LETM1,FGF2,TPM4,DLGAP4,AKAP12,NUP160,MAT2A,PCDH7,DKK1,SH2B3,FARSA,EPN2,SLC7A11,TBX3,TNFRSF1A,ZEB1,PDLIM5,RPS6KB2,TOP1 |
| 6.889e-06 | -11.89 | ERB2_UP.V1_DN | MSigDB lists | ERB2_UP.V1_DN | 186 | 46 | 17758 | 2279 |
IFT57,C16orf45,DBF4,SMAD7,ZNF107,ID2,KIF5C,PLA2G12A,RMI1,FLNB,RRN3,PMAIP1,CBR4,MYC,IFIT5,PAK1IP1,LTN1,GREB1,NOC3L,PEG10,NRIP1,AGL,PRMT3,MYB,RANBP6,PTBP2,SSFA2,MTIF2,NOL8,CPOX,CAV1,MBNL2,DDX60,EHBP1,RAD54B,IRS1,TAF2,RBBP8,CEBPZ,RNF138,HSPB8,ZNF430,ADAM9,PUS1,ZBTB11,HS2ST1 |
| 6.936e-06 | -11.88 | MDC1 (mediator of DNA-damage checkpoint 1) | protein interactions | 9656 | 185 | 49 | 16036 | 2270 |
HERC2,CUL7,SUPT6H,PLRG1,SIRT7,FANCD2,CSNK2A1,SMARCA4,PHGDH,POGZ,FLNB,ANAPC1,BRE,ATXN2,BANF1,ANAPC10,RMDN3,CPSF3,LPCAT1,TRIP13,MICAL3,AUP1,SERBP1,SF3A1,HMBOX1,EXOSC2,RFC4,LSM12,WDR18,HDAC8,BRCA1,POLR2A,ZNF251,RPA1,PYCR1,PAF1,CDC16,SMARCC1,TP53BP1,COPS5,H2AFX,ATM,SLC25A11,CLU,PGAM5,BRCC3,WDR33,TPM1,ANAPC4 |
| 7.072e-06 | -11.86 | RNA splicing, via transesterification reactions | biological process | GO:0000375 | 251 | 58 | 16441 | 2138 |
SART1,ZCCHC8,PRPF31,TFIP11,PLRG1,SF3A3,PPIL1,PDCD7,NOL3,PRPF39,ZMAT2,DHX35,RSRC1,HNRNPA3,UBL5,MBNL1,SNW1,SRSF2,MPHOSPH10,BCAS2,PHF5A,CTNNBL1,CWC27,BUD31,GPATCH1,CELF1,GEMIN4,CPSF3,PRMT5,SRRM2,PABPC1,HNRNPM,SRPK2,PRPF19,SF3A1,SCAF11,SNU13,PTBP2,DDX41,SKIV2L2,USP49,TRA2A,PSPC1,PNN,CLNS1A,POLR2A,GEMIN5,PRPF40B,SYNCRIP,HNRNPR,SPEN,LUC7L3,HNRNPH3,PQBP1,NCBP2,PRPF4,FUS,PPIL3 |
| 7.213e-06 | -11.84 | V$NMYC_01 | MSigDB lists | V$NMYC_01 | 260 | 59 | 17758 | 2279 |
CHST11,MINK1,PPARGC1B,ST6GAL1,CMTM8,UBXN1,RNF43,TIMM10,FOXO3,MFHAS1,PABPC4,IQGAP2,NOP56,DCTPP1,PRKCE,CNST,SLC38A5,ARMC6,VGF,IGF2BP1,CELF1,ALDH18A1,FBL,ETV1,ZCCHC7,PABPC1,ANGPT2,TOP1,MTHFD1,RTN4RL2,NRAS,TXLNG,MON1A,PPAT,TLE3,EIF3J,ELOVL6,ARRDC3,KIAA0586,SCFD2,SEMA3F,KRTCAP2,SLC9A5,UBR4,POLR3A,CTIF,BATF3,PES1,POLR3E,CTAGE5,TRMT2A,AEN,FKBP5,GCSH,RAB30,IPO4,SLC43A1,ATXN7L2,KAT6A |
| 7.221e-06 | -11.84 | DDX24 (DEAD (Asp-Glu-Ala-Asp) box helicase 24) | protein interactions | 57062 | 107 | 33 | 16036 | 2270 |
BCCIP,NIFK,DDX18,SIRT7,MKS1,CSNK2A1,NOP56,TERF2IP,DDX56,MYC,SHMT2,DDX31,RNF2,NOC3L,FBL,PRF1,ZC3H3,FTSJ3,TERF2,SPTAN1,SNU13,DDX24,GNL3,HSPA5,NOL6,BCS1L,BRCA1,DKC1,NOP58,PUM3,PWP1,PES1,POLR1C |
| 7.230e-06 | -11.84 | KIM_WT1_TARGETS_12HR_DN | MSigDB lists | KIM_WT1_TARGETS_12HR_DN | 203 | 49 | 17758 | 2279 |
CYP24A1,HMGA2,CUL4A,RWDD1,DDX18,DBF4,SMAD7,ZFP36L1,PLEK2,TGFBR2,NOP56,IGF2BP3,RAP1A,SRSF2,NOP16,MYC,TRIAP1,ZNF148,CD44,FXN,HN1,TMPO,ARNTL2,BDNF,CRIM1,KLHL23,GNL3,SFSWAP,ZBED4,MINA,MCL1,PNN,HERPUD1,YTHDF2,GLS,BAZ2B,MYBBP1A,SYNCRIP,PMEPA1,POLR3E,SYNGR2,AEN,SEMA3C,PUS1,PFDN2,NR2F2,NOLC1,ADK,CORO2B |
| 7.389e-06 | -11.82 | GSE3982_DC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_UP | 192 | 47 | 17758 | 2279 |
PCNT,PRDX6,ITFG1,LAGE3,DPM3,PIBF1,LPIN1,DST,S100A10,INTS7,NUP133,ATIC,BANF1,TRIAP1,MYH3,VPS52,PTGS1,PCOLCE2,RAN,FBL,CNOT4,MTHFD1,EVL,PDE4A,MTIF2,ZBED4,MINA,R3HDM1,C11orf49,PTK2,SOX4,PALLD,MAT2A,YIF1A,EPRS,ETFDH,RARS,INTS5,CUL2,H2AFX,FTSJ1,WDR7,TSSC1,SQLE,PUS1,NRP1,MORC2 |
| 7.393e-06 | -11.81 | regulation of cellular metabolic process | biological process | GO:0031323 | 5773 | 841 | 16441 | 2138 |
ASCC1,THOC5,CHAC1,HLTF,CCNL2,ZNF44,LPAR3,NOS1AP,AMBRA1,SKI,ZNF37A,TOM1L1,NEK6,SREBF2,ZFHX3,IKZF5,PMAIP1,NSRP1,MAD1L1,WIZ,ZNF148,FNIP2,KDM5C,HRG,HMBOX1,EIF4E3,NRAS,GNL3,EHMT1,NFIA,KRBOX4,RFX2,AKAP12,C5AR1,DCUN1D5,ZNF197,STOML2,DDX3X,AHNAK,ZNF266,BRCA2,SUPT4H1,SSU72,RAD18,MPV17,FIS1,DIRAS1,RUNX1,ZNF532,P2RY11,MEF2C,BANP,EPM2AIP1,TRIP6,SLK,KHDRBS1,SIRT7,PIK3R4,RSF1,CDC73,ABCA7,RBM20,CNST,UBE3A,APLF,ZNF326,MED24,ANP32B,CCDC88C,PRMT5,ZNF518B,MAP3K12,PABPC1,MYB,HMGCR,PEA15,ZNF675,GATAD2B,FADS1,GTF2H3,BDNF,WDR61,STAG1,ZNF587,RB1CC1,PRDM16,ARID5B,EIF4A2,ZNF512B,RYR2,USP10,SMARCD3,ARRDC4,MBNL2,CPT1A,TRIM37,SRA1,ONECUT2,ABCF1,ZNF655,ZNF783,IRS1,TASP1,KPNA1,GTF2A1,PDLIM1,RPL28,EHMT2,TRAP1,CDK9,CCDC85B,ZNF160,CNOT6,SPRED2,MAP2K5,ZNF516,TRERF1,GTF2H2C,PAFAH1B1,NPAS2,PDK4,DDR2,MYH9,SAFB2,HSPA1A,TMEM150C,ACD,ZKSCAN1,WAC,MMP14,PERP,KMT2D,ZNF480,EIF3J,ATF7IP2,MEF2D,FGFR1,PDE8B,TAF2,FBXL5,CDC16,KDM4B,ELP2,NSMCE2,PEMT,HIPK2,HOXA3,RPS6KB1,FUS,BRCC3,ZBTB11,YEATS2,MAPT,COMMD10,HMGA2,ZNF786,SHQ1,INSIG2,TRAK1,ID2,JMJD6,GAS6,AKT1S1,TRIM22,BHLHE40,TGFB2,ZNF691,PSMF1,MBNL1,TADA3,SNW1,NPRL2,GATC,SUV39H2,TAF3,ZNF710,SAMD4A,SOX6,SPTAN1,FGF9,USP42,NXN,IL6R,ZNF467,UBE2K,FOXC1,UBC,ANXA1,OXSR1,TRIB3,NSD1,SRCAP,BAZ2B,ARID3B,HERC1,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,KDM4C,TRIM16,AAMDC,GPBP1L1,PPARGC1B,TFIP11,CSNK2A1,NLE1,BIRC2,HNRNPLL,MAP2K3,ABL2,ECM1,SRSF2,PHF5A,DHX33,HKR1,ZNF85,RAN,ZNF3,ETV1,ZMYM2,SLC25A23,TMPO,CDC37,PTPRK,CHD9,RBCK1,ZNF124,GCNT2,ATF4,AEBP2,PPARG,BAZ2A,ZNF414,CDK4,HSPA5,MED27,GMFB,SUMO3,BRCA1,ODC1,ZNF91,MLLT10,KIF16B,DYRK1B,HPRT1,ZNF622,TCF7L1,INSIG1,TP53BP1,CHD3,PER1,EEFSEC,E2F4,SOCS4,TNFRSF1A,ADAM9,DLX2,BEND6,UQCC2,USP15,TTN,FOXO1,CLK1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,HES6,BARX2,ZFP36L1,TRIM15,ZIC2,RLF,ARID1B,RNF40,SUB1,MLX,ZNF358,CEP290,MBD2,VPS72,SAMD11,NDRG4,GTF2H1,VAPB,CTR9,TIMELESS,ICE2,WNT16,LRSAM1,CAMKK2,PAXBP1,CRADD,USP49,TLE3,SETD2,UTP15,SUPT5H,VAC14,NR2F1,TCF7L2,ATXN7,SPAG9,SYNCRIP,IRAK2,TBPL1,ZNF430,DTD1,TESC,PRKAR2A,BCCIP,USP7,ID1,CYLD,ARID2,RBFOX2,NTSR1,PPP2R2A,RIPK1,ZNF83,SSBP2,ZNF709,PELP1,ZNF121,KDM1A,ZBTB21,NRF1,JAG1,NUP133,GRIN2C,DNAJB6,IKBKB,RNF2,ZFP37,ETF1,AHCYL1,SPIDR,PRMT3,CASP10,CTC1,PRPF19,SEC24A,KAT8,KDM3B,PCGF3,DDX41,KIRREL2,RAB7A,C1QTNF1,AKAP13,ENC1,ZNF251,PUM3,EIF3H,USP36,SMAD3,RANBP2,RBBP8,SIX5,ZNF333,KLF4,ATG7,ZNF436,PUS1,ZNF18,MED20,EIF2B3,ZNF589,PKIB,PARD3,ZNF507,NIFK,ESCO1,MINK1,MIF4GD,MAP3K13,RFX1,AGO2,VARS,FOXP1,HIST2H2AB,ANKRD54,ZNF594,PTPN2,ZNF561,TMEM161A,HIST2H3D,SELT,FBXO31,CD44,SNAPC5,TRNP1,SMARCAD1,FOXN3,ZNF654,ZMYM5,TEX14,DHX34,HIST1H4J,PIK3CB,POLR3A,ZRANB3,MKX,DKK1,POLR3G,L3MBTL3,TAF4,SET,TBX3,CSRNP1,MSH3,GLG1,BCAS3,EIF2S1,USP20,RBM26,ZNF32,MYRF,RBPJ,TAF12,NR2F2,ZNF292,MYCBP2,CUL4A,PRKAB2,PRKCA,GABPB2,UBR5,AARS,LPIN1,MGA,GIPR,ZFYVE28,RNF111,CHD2,ME1,MEIS3,ZNF646,DDN,DPF3,SETD1B,NR6A1,EYA3,TCEB3,CUX1,SUPT20H,DENND4A,SON,SAP30BP,SPOP,GZF1,DOT1L,SKIL,DDAH2,TRRAP,CCNT1,SH3RF1,LSM14A,ARL6IP5,ZNF81,HIC2,TNFRSF10D,NRP1,BMI1,RFXAP,SPOCK3,PTPN14,WDR75,IFT57,DROSHA,EGR1,JUP,LARS2,ZHX3,ANKRD17,OPHN1,CENPB,GTF2IRD1,PID1,PDCD5,TGFBR2,CHD5,IGF2BP3,FKBP1A,PRKCE,HR,ENTPD5,ZNF586,NOVA2,MYC,IGF2BP1,LPCAT1,CAV2,TERF2,ADARB1,SYNGAP1,RREB1,POLA1,RAP1B,ARID1A,NELFA,PLCB1,ZNF850,ARIH2,PHF6,ZNF425,CAT,ASCC3,EPRS,KIDINS220,NSF,HIF1A,PMEPA1,SPEN,MED15,ZBTB12,PURB,DPEP1,NCOR1,SMYD3,ZFHX2,ZNF254,PTCD2,LIN28B,BIRC6,ZBTB37,FOSL2,RING1,IGSF1,PAIP2,BLOC1S2,TERF2IP,CHD7,ZNF827,SLX4,SHC1,KDM2A,PPID,UCHL5,LPIN2,SOCS6,DTNBP1,SERPINH1,KMT2A,CDK12,CASP8AP2,SAP30,BRD4,GON4L,PDK1,MTIF2,DLG4,SATB2,MED16,PNN,SETD7,STK10,ERC1,SERP1,SNCA,ZBTB25,VDR,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,G6PD,DNAJA3,ZNF236,MBTD1,H2AFX,TRAF3,ANXA2,SETD6,MID1,NOSTRIN,NCOR2,BRAF,TCF3,ZNF280C,NFX1,RCAN1,MYNN,MLH1,IKBKAP,NOL3,RPS6KA5,GIGYF2,PHLDA2,FOXO3,MAD2L2,NEDD4,SFR1,ZNF239,ABL1,ZNF483,COMMD9,PTRF,ELP5,TRIAP1,RDX,CELF1,YBX3,LARP4B,ERRFI1,MAP3K14,MBTPS2,CLK2,FAM120B,TSHZ1,SLC40A1,PXN,APEX1,WDFY3,ZFYVE1,KCNMA1,PTK2,KLF6,GUF1,POLR2A,ZFP62,KLHL22,ZNF155,IREB2,ATM,APAF1,BRWD3,DDIT3,KAT6A,STK4,ZNF76,EIF3C,UBN1,ATRX,NF1,KMT2E,PTPRA,RCHY1,ZNF107,BCOR,SIRT2,SNAPC4,SMARCB1,ANAPC1,RAP1A,YLPM1,JAZF1,GPR87,ANAPC11,ANAPC10,RELB,ZEB1,PCOLCE2,HCFC2,OGG1,TRIP13,PRKACB,TRIM14,CARM1,ELOF1,SRPK2,ZBTB17,DEAF1,TNK2,TRIM13,SESN2,TXLNG,ZNF195,SIRT6,ZNF680,TFPI,ARRDC3,MINA,HDAC8,CAV1,ZSCAN2,SOX4,KMT2C,TAF9B,PAF1,UBTF,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,MKL2,PQBP1,CLU,ZC3H8,ZNF397,NOCT,DMTF1,MTCH1,EMSY,TNRC6A,FN1,TAF1,PAX2,DPF2,UBXN1,MED13L,SMG7,RHBDD1,NAMPT,DDIT4,TOX4,RNF141,ELL,P3H1,ZNF354A,ATXN2,BUD31,NRIP1,ZNF629,VOPP1,ZNF234,JMJD1C,ELP3,WBSCR22,ZFP14,PSMA1,WWC1,PRDM1,EIF2A,HERPUD1,ISG15,UBE2E1,APBB3,MYBBP1A,RRAGA,HK2,ZFP90,TBL1X,AGO3,N4BP2L2,ZBTB24,TCF12,ZNF706,DLL4,ASH1L,FEZ2,CELSR3,CEMIP,TNXB,SMARCA4,PBX1,CSTA,PIBF1,ZSCAN5A,RRN3,MPHOSPH10,BRE,SOCS1,CAMTA2,NVL,ZNF142,FHIT,MET,ZNF460,UTP4,HTRA2,MOSPD1,MAML3,PRAME,PTBP2,TFCP2,SFSWAP,GRHL3,NLN,POU2F1,ATXN1,DKC1,BATF3,ZC3H12A,IKZF4,ADNP,ZNF557,COPS5,CEBPZ,ARNTL,DUSP19,SRFBP1,HEATR1,SCARB1,NFRKB,USP11,BRD9,DNAJC2,TNIK,SUPT6H,CAMK1,H2AFJ,PPHLN1,MED18,IGF2BP2,ATF7IP,PPP1R1C,SOGA1,PIP4K2A,BMP6,SFI1,PRKCH,HAS3,STC2,DMRT1,PKNOX1,RPS6KB2,KDM6B,ARNTL2,MSX1,KDM5B,FGF2,CRIM1,ZNF821,TEAD1,PSPC1,KDM5A,PSMC3IP,ZNF324B,SCMH1,PDE2A,MEN1,EIF5B,ZNF407,SYMPK,RERE,CTIF,ZNF221,HSPA1B,ZNF708,GADD45A,CUL2,ZRANB2,NCBP2,NFKBIB,ZAK,HRH1 |
| 7.453e-06 | -11.81 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 900 | 160 | 17775 | 2278 |
NF1,PTPRA,TNFRSF21,TRPM6,MKS1,CSNK2A1,RNF43,STK33,PRKCA,NLE1,UBR5,MAP2K3,SMARCB1,RTN1,ABL2,ANAPC1,SRSF2,SREBF2,NEK6,ATG3,XRCC2,YARS,SRRM2,CDK6,LONP1,PRKACB,SRPK2,LAMA4,FLNC,TNK2,NRAS,ALDH1L2,CDK4,ANK2,NOL8,TFPI,AP4B1,NOL6,KSR2,LAMA2,BRCA1,SGK2,SON,CHAF1A,DYRK1B,TRRAP,EIF4ENIF1,HLCS,SOCS4,SGSM2,CSMD3,RIOK1,RUNX1,TSEN2,WDR66,SEC24D,TAF1,CLK1,TRIO,PIK3R4,TGFBR2,DNAH1,PRKCE,SIPA1L3,ASAP1,SCAF1,INTS7,PDE10A,SEMA3D,MAP3K12,PABPC1,SIK3,CAMKK2,JMJD1C,OBSCN,C19orf70,MTR,PHF6,ATP9B,DYNC1H1,KIDINS220,ZZEF1,SNAP23,RIOK3,GPN1,TBCK,MAP2K4,CHMP2A,UPK3B,BIRC6,URB2,PDK4,DDR2,SMARCA4,RIPK1,RPGRIP1L,RIOK2,FLAD1,VPS18,ANKRD13A,PRKD3,BRE,KDM2A,CCDC50,RPS6KL1,IKBKB,ADCK4,MET,KMT2A,CDK12,ZCCHC14,BRD4,PDK1,SFSWAP,TBC1D16,STK10,FGFR1,TJAP1,SMAD3,CAMK2D,HIPK2,RPS6KB1,MDN1,PDCD11,SMG1,BCKDK,SSH2,TNIK,BRAF,SULT1C2,SUPT6H,MAP3K13,CAMK1,ATG2B,WDR26,CSNK1A1,FAM49A,FOXO3,PRKCH,ABL1,PVRL3,PRICKLE2,CLK2,RPS6KB2,SPTAN1,TTLL5,ADAMTSL3,TOP3A,TEX14,NAALADL2,OXSR1,TRIB3,BAZ2B,TMEM237,SRD5A3,ATM,RPS6KC1,KIF1B,ZAK,STK4 |
| 7.491e-06 | -11.80 | TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 447 | 90 | 17758 | 2279 |
TCF12,ZNF254,ZNF76,ASH1L,UBN1,NPAS2,PPARGC1B,PBX1,FOSL2,SNAPC4,GABPB2,SMARCB1,NRF1,SREBF2,ZFHX3,JAZF1,ZEB1,ZNF148,CHD2,ETV1,HCFC2,TRIP13,MAML3,DEAF1,ATF4,TFCP2,NR6A1,PPARG,MED27,TCEB3,CUX1,HDAC8,MED16,BRCA1,BATF3,SKIL,SMAD3,TAF2,RBBP8,SUPT4H1,ELP2,SMARCC1,CHD3,CCNT1,COPS5,MKL2,CEBPZ,ARNTL,TNFRSF1A,NFRKB,MED20,RUNX1,FOXO1,PAX2,TRAK1,NFX1,ATF7IP,IKBKAP,FOXO3,BMP6,ABL1,TADA3,SUB1,SNW1,ELL,ZNF354A,VPS72,MYC,BUD31,MED24,GTF2H1,NRIP1,SNAPC5,APEX1,RREB1,KDM5A,ELP3,SMARCD3,PRDM1,MEN1,SUPT5H,TCF7L2,SRCAP,NSD1,HIF1A,CDK9,TBX3,NCOR1,NR2F2,DDIT3 |
| 7.546e-06 | -11.79 | MORF_HDAC2 | MSigDB lists | MORF_HDAC2 | 272 | 61 | 17758 | 2279 |
MCM6,ANKRD17,DDX18,PRPF31,KHDRBS1,DDX19A,ACTR3,RCHY1,RTN4,XPO7,HDDC2,POM121,PABPC4,NDUFB3,CAD,NDUFV1,EIF2S2,ANXA7,SEC24C,MRPS27,TNPO3,ETF1,SSBP1,POLE3,YARS,GNG5,HNRNPM,SERBP1,NUDC,RFC4,IFRD1,CAMKK2,GARS,SKIV2L2,MTIF2,IDH3G,R3HDM1,ATG12,MARS,BMS1,MCM2,DKC1,SON,SERP1,ABCF1,TARS,POLR2A,CLNS1A,UBE2E1,CHAF1A,RPA1,PWP1,EPRS,HNRNPR,COPS5,COQ9,SET,CEBPZ,GPN1,NCBP2,XPO6 |
| 7.887e-06 | -11.75 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 3077 | 469 | 17775 | 2278 |
ARHGAP26,MYCBP2,POLB,ADAM19,THOC5,LUZP1,PRKCSH,CNTNAP3,PRKAB2,SBF2,ADAMTS6,HLTF,PRKCA,NBEAL1,NUP160,SYNJ1,LPAR3,UBR5,GABPB2,GIPR,EXOC1,PDZD2,SREBF2,ZFHX3,PMAIP1,RABGAP1L,RASSF3,MAD1L1,ZNF148,SRRM2,CDK6,NRAS,PTPRM,GNL3,RBM28,SLC9A5,SH3GL1,SPOP,DDX3X,AHNAK,BRCA2,RAD18,LSM14A,SH3RF1,CCNT1,LRRC40,VPS13D,DIRAS1,DNAH2,RUNX1,CCNB1IP1,NRP1,FIP1L1,ZNF598,SPOCK3,ZNF532,LPP,MEF2C,CARS,TRIP6,CELSR1,NHS,PIK3R4,GTF2IRD1,PID1,RSF1,TGFBR2,CDC73,TECTA,PRKCE,UBE3A,SLC7A11,DHX37,USPL1,INTS7,ASAP1,CACNB2,ATIC,MYC,ALKBH8,GTF3C3,ANP32B,SCAF11,PEA15,SIK3,EXOSC2,GTF2H3,RREB1,PRDM16,PCCA,RDH10,RAP1B,USP10,ST6GALNAC3,ARID1A,TRIM37,EHBP1,USP46,NCDN,IRS1,DYNC1H1,ZNF425,LRP1B,HIF1A,SPEN,ZCCHC6,SQLE,KIAA0196,NCOR1,MAP2K4,COG5,SPRED2,ABCA3,SPATA2L,MAB21L3,VTI1A,DDR2,MYH9,SLC25A44,FOSL2,PABPC1L,LTB4R,FLNB,NOP56,CHD7,SHC1,KDM2A,UCHL5,LPIN2,SOCS6,TTC3,MSH4,KMT2A,ZC3H3,ATP6AP1L,CDK12,LYST,PMS1,GARS,KMT2D,BRD4,GON4L,PDK1,STAMBP,MTIF2,MARCH6,CCNDBP1,MEF2D,GSTCD,STK10,ERC1,FGFR1,PES1,TAF2,BAZ1A,ARHGAP21,IQCH,KDM4B,ZNF236,CAMKMT,LARGE,HOXA3,ACP1,SLC4A7,RPS6KB1,TRAF3,FUS,MDN1,BRCC3,TRIM36,MORC2,ZNF786,SSH2,NCOR2,BRAF,UTP14A,XPC,B4GALT5,C10orf2,SESTD1,TCF3,SF3A3,RCAN1,MLH1,TGFB2,GDPD5,FOXO3,MAD2L2,NEDD4,ABL1,NPRL2,NEBL,GATC,LTN1,LARP4B,FBXL19,SOX6,PFKFB4,FER1L5,FGF9,PXN,APEX1,WDFY3,ZFYVE1,FZD3,TMEM126A,ADSL,R3HDM2,KLF6,CASC1,FBXO21,NSD1,HELZ,HERC1,RNF138,ATM,MYOM2,BMP4,BRWD3,RABEP1,DDIT3,GPATCH4,STK4,CYP24A1,ZNF76,PHF3,ATRX,NF1,GPBP1L1,KIF5A,POLR1A,HECTD3,CSNK2A1,ZNF107,BCOR,FAM13A,TTI1,TMEM132A,SCAF8,BIRC2,MAP2K3,SMARCB1,WNT2B,ABL2,DST,RAP1A,YLPM1,LONRF2,MARVELD2,JAZF1,XRCC2,ANAPC11,SLC39A7,NCKIPSD,ANKRD11,MYH3,METTL8,UBAP2L,RELB,ZEB1,GPATCH1,JOSD1,RAN,ZMYM2,ETV1,OGG1,PRKACB,LONP1,CDC37,VPS13B,TMPO,LAMA4,DBN1,FLNC,FBXW4,RBCK1,ABCC4,MIOS,PPARG,CDK4,GPCPD1,KSR2,LAMA2,CAV1,BRCA1,SGK2,KMT2C,CRYBG3,MLLT10,BSN,RHOU,HPRT1,TCF7L1,SUFU,TP53BP1,E2F4,PER1,CCDC146,MKL2,SOCS4,TNFRSF1A,RAD51B,CSMD3,ADAM9,MAGI1,ZNF397,COPS6,USP15,FBXO45,MCM6,FOXO1,TAF1,SMAD7,FAN1,MAPK8IP3,LAMTOR3,PCSK7,QSER1,PHGDH,SPIRE1,DOPEY1,ELL,ATXN2,MBD2,GTF2H1,CTR9,WNT16,GMDS,AKAP11,MSI2,RANBP6,LAMC1,PDE4A,USP49,TLE3,XPO5,SETD2,JMJD1C,TBXAS1,WWC1,LIG4,PRDM1,TCF7L2,SPAG9,PALB2,SDCCAG8,ZNF430,ZFP90,DDX10,FNBP1L,PDSS2,PRKAR2A,PDE9A,DMXL2,TCF12,USP7,DLL4,ASH1L,CYLD,ARID2,SLC2A1,NTSR1,SMARCA4,RIPK1,PBX1,PPP2R2A,TNKS1BP1,RADIL,PIBF1,ZNF121,RPAIN,DHX35,PLXNB1,KDM1A,SBDS,JAG1,DUS4L,SOCS1,NVL,IKBKB,ZNF142,ZFP37,RNF2,MET,AUP1,CASP10,MAML3,TLCD1,ARHGAP17,PHLDB2,THSD4,PARP2,METTL2A,R3HDM1,TMEM123,ATP8B2,NUP214,EIF3H,S100A16,USP36,BTBD11,EXO1,PLIN2,RANBP2,RBBP8,COPS5,ITGA2,DUSP19,PRRT3,DISP1,RNF130,HEATR1,USP11,SEPT5,BRD9,MUTYH,SMG1,PARD3,TMCC1,ATXN7L2,DMGDH,BCKDK,ESCO1,PDE4B,CLSTN2,MAP1S,IGF2BP2,FOXP1,CSNK1A1,FAM49A,CTNNBL1,ZNF561,CWC27,GREB1,SHMT2,DDX31,POLR1B,CPNE7,AMOT,SNAPC5,RPS6KB2,TOP1,ADAMTSL3,FGF2,CRIM1,SMARCAD1,TEX14,RAP1GDS1,MARS,ARHGEF12,PALLD,GPNMB,MEN1,PIK3CB,DKK1,ZRANB3,ZNF708,DAGLB,WDR35,MPP7,SET,MSH3,FNTB,DNAJC12,USP20,ZRANB2,RBPJ,NFKBIB,ITGB4 |
| 7.887e-06 | -11.75 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 3077 | 469 | 17775 | 2278 |
ARHGAP26,MYCBP2,POLB,ADAM19,THOC5,LUZP1,PRKCSH,CNTNAP3,PRKAB2,SBF2,ADAMTS6,HLTF,PRKCA,NBEAL1,NUP160,SYNJ1,LPAR3,UBR5,GABPB2,GIPR,EXOC1,PDZD2,SREBF2,ZFHX3,PMAIP1,RABGAP1L,RASSF3,MAD1L1,ZNF148,SRRM2,CDK6,NRAS,PTPRM,GNL3,RBM28,SLC9A5,SH3GL1,SPOP,DDX3X,AHNAK,BRCA2,RAD18,LSM14A,SH3RF1,CCNT1,LRRC40,VPS13D,DIRAS1,DNAH2,RUNX1,CCNB1IP1,NRP1,FIP1L1,ZNF598,SPOCK3,ZNF532,LPP,MEF2C,CARS,TRIP6,CELSR1,NHS,PIK3R4,GTF2IRD1,PID1,RSF1,TGFBR2,CDC73,TECTA,PRKCE,UBE3A,SLC7A11,DHX37,USPL1,INTS7,ASAP1,CACNB2,ATIC,MYC,ALKBH8,GTF3C3,ANP32B,SCAF11,PEA15,SIK3,EXOSC2,GTF2H3,RREB1,PRDM16,PCCA,RDH10,RAP1B,USP10,ST6GALNAC3,ARID1A,TRIM37,EHBP1,USP46,NCDN,IRS1,DYNC1H1,ZNF425,LRP1B,HIF1A,SPEN,ZCCHC6,SQLE,KIAA0196,NCOR1,MAP2K4,COG5,SPRED2,ABCA3,SPATA2L,MAB21L3,VTI1A,DDR2,MYH9,SLC25A44,FOSL2,PABPC1L,LTB4R,FLNB,NOP56,CHD7,SHC1,KDM2A,UCHL5,LPIN2,SOCS6,TTC3,MSH4,KMT2A,ZC3H3,ATP6AP1L,CDK12,LYST,PMS1,GARS,KMT2D,BRD4,GON4L,PDK1,STAMBP,MTIF2,MARCH6,CCNDBP1,MEF2D,GSTCD,STK10,ERC1,FGFR1,PES1,TAF2,BAZ1A,ARHGAP21,IQCH,KDM4B,ZNF236,CAMKMT,LARGE,HOXA3,ACP1,SLC4A7,RPS6KB1,TRAF3,FUS,MDN1,BRCC3,TRIM36,MORC2,ZNF786,SSH2,NCOR2,BRAF,UTP14A,XPC,B4GALT5,C10orf2,SESTD1,TCF3,SF3A3,RCAN1,MLH1,TGFB2,GDPD5,FOXO3,MAD2L2,NEDD4,ABL1,NPRL2,NEBL,GATC,LTN1,LARP4B,FBXL19,SOX6,PFKFB4,FER1L5,FGF9,PXN,APEX1,WDFY3,ZFYVE1,FZD3,TMEM126A,ADSL,R3HDM2,KLF6,CASC1,FBXO21,NSD1,HELZ,HERC1,RNF138,ATM,MYOM2,BMP4,BRWD3,RABEP1,DDIT3,GPATCH4,STK4,CYP24A1,ZNF76,PHF3,ATRX,NF1,GPBP1L1,KIF5A,POLR1A,HECTD3,CSNK2A1,ZNF107,BCOR,FAM13A,TTI1,TMEM132A,SCAF8,BIRC2,MAP2K3,SMARCB1,WNT2B,ABL2,DST,RAP1A,YLPM1,LONRF2,MARVELD2,JAZF1,XRCC2,ANAPC11,SLC39A7,NCKIPSD,ANKRD11,MYH3,METTL8,UBAP2L,RELB,ZEB1,GPATCH1,JOSD1,RAN,ZMYM2,ETV1,OGG1,PRKACB,LONP1,CDC37,VPS13B,TMPO,LAMA4,DBN1,FLNC,FBXW4,RBCK1,ABCC4,MIOS,PPARG,CDK4,GPCPD1,KSR2,LAMA2,CAV1,BRCA1,SGK2,KMT2C,CRYBG3,MLLT10,BSN,RHOU,HPRT1,TCF7L1,SUFU,TP53BP1,E2F4,PER1,CCDC146,MKL2,SOCS4,TNFRSF1A,RAD51B,CSMD3,ADAM9,MAGI1,ZNF397,COPS6,USP15,FBXO45,MCM6,FOXO1,TAF1,SMAD7,FAN1,MAPK8IP3,LAMTOR3,PCSK7,QSER1,PHGDH,SPIRE1,DOPEY1,ELL,ATXN2,MBD2,GTF2H1,CTR9,WNT16,GMDS,AKAP11,MSI2,RANBP6,LAMC1,PDE4A,USP49,TLE3,XPO5,SETD2,JMJD1C,TBXAS1,WWC1,LIG4,PRDM1,TCF7L2,SPAG9,PALB2,SDCCAG8,ZNF430,ZFP90,DDX10,FNBP1L,PDSS2,PRKAR2A,PDE9A,DMXL2,TCF12,USP7,DLL4,ASH1L,CYLD,ARID2,SLC2A1,NTSR1,SMARCA4,RIPK1,PBX1,PPP2R2A,TNKS1BP1,RADIL,PIBF1,ZNF121,RPAIN,DHX35,PLXNB1,KDM1A,SBDS,JAG1,DUS4L,SOCS1,NVL,IKBKB,ZNF142,ZFP37,RNF2,MET,AUP1,CASP10,MAML3,TLCD1,ARHGAP17,PHLDB2,THSD4,PARP2,METTL2A,R3HDM1,TMEM123,ATP8B2,NUP214,EIF3H,S100A16,USP36,BTBD11,EXO1,PLIN2,RANBP2,RBBP8,COPS5,ITGA2,DUSP19,PRRT3,DISP1,RNF130,HEATR1,USP11,SEPT5,BRD9,MUTYH,SMG1,PARD3,TMCC1,ATXN7L2,DMGDH,BCKDK,ESCO1,PDE4B,CLSTN2,MAP1S,IGF2BP2,FOXP1,CSNK1A1,FAM49A,CTNNBL1,ZNF561,CWC27,GREB1,SHMT2,DDX31,POLR1B,CPNE7,AMOT,SNAPC5,RPS6KB2,TOP1,ADAMTSL3,FGF2,CRIM1,SMARCAD1,TEX14,RAP1GDS1,MARS,ARHGEF12,PALLD,GPNMB,MEN1,PIK3CB,DKK1,ZRANB3,ZNF708,DAGLB,WDR35,MPP7,SET,MSH3,FNTB,DNAJC12,USP20,ZRANB2,RBPJ,NFKBIB,ITGB4 |
| 8.017e-06 | -11.73 | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN | 187 | 46 | 17758 | 2279 |
SEPHS2,FBXO45,SNX27,C14orf159,GYG1,RNASEH2B,GDPD5,LCLAT1,REEP5,MAD2L2,RSPRY1,KCTD11,CEP290,KDELC1,ANAPC10,HIBCH,ZNF518B,POLR1E,NAA35,CPSF3L,ELOF1,ALG6,ANKRD33B,R3HDM1,USP10,KRTCAP2,GPNMB,RBM28,UBE2K,CRYBG3,DOT1L,STOML2,EXO1,GNG2,C6orf141,ZNF266,SLC30A3,SYNCRIP,FGFBP1,PER1,EXOC4,GPN1,PEX13,PREPL,POLR1C,TXN2 |
| 8.081e-06 | -11.73 | PUM3 (pumilio RNA binding family member 3) | protein interactions | 9933 | 63 | 23 | 16036 | 2270 |
WDR36,NIFK,DDX24,UTP14A,DDX18,GLTSCR2,SKIV2L2,GNL3,SIRT7,DKC1,NOP58,NOP56,PES1,PWP1,DDX56,CEBPZ,SHMT2,RNF2,FBL,POLR1C,DDX10,ZC3H3,FTSJ3 |
| 8.213e-06 | -11.71 | GRESHOCK_CANCER_COPY_NUMBER_UP | MSigDB lists | GRESHOCK_CANCER_COPY_NUMBER_UP | 314 | 68 | 17758 | 2279 |
TCF12,ARHGAP26,CYLD,NF1,FANCD2,MYH9,PBX1,SBDS,SMARCB1,ABL2,JAZF1,NCKIPSD,MET,ETV1,ZMYM2,CDK6,PMS1,NRAS,BRD4,PPARG,CDK4,BRCA1,NUP214,ERC1,FGFR1,SH3GL1,MLLT10,BRCA2,SUFU,PER1,RAD51B,RUNX1,CCNB1IP1,SEPT5,FIP1L1,MUTYH,LPP,HMGA2,CARS,BRAF,FOXO1,XPC,TCF3,PCSK7,MLH1,FOXO3,CHN1,ABL1,ELL,MYC,ATIC,TOP1,MSI2,GPHN,PRDM16,EIF4A2,TPM4,RAP1GDS1,ARHGEF12,MEN1,KLF6,NSD1,SET,ATM,DDX10,MAP2K4,RABEP1,DDIT3 |
| 8.302e-06 | -11.70 | REGULATION_OF_METABOLIC_PROCESS | MSigDB lists | REGULATION_OF_METABOLIC_PROCESS | 788 | 143 | 17758 | 2279 |
ZNF76,EIF3C,UBN1,ATRX,PPARGC1B,BCOR,SIRT2,GABPB2,MAP2K3,SMARCB1,SREBF2,PHF5A,ZFHX3,JAZF1,ZEB1,ZNF148,CHD2,HCFC2,CARM1,TNK2,ATF4,NR6A1,LIMA1,PPARG,MED27,CUX1,TCEB3,HDAC8,BRCA1,UBTF,DYRK1B,HPRT1,SUPT4H1,GATA6,SUFU,DNAJC1,CHD3,PER1,MKL2,PQBP1,TNFRSF1A,RUNX1,EGR1,FOXO1,CDC42EP2,ZHX3,KHDRBS1,SMG7,RSF1,SUB1,ZNF354A,VPS72,MYC,BUD31,TIMELESS,GTF2H1,CCDC88C,NRIP1,PABPC1,TERF2,CAMKK2,RREB1,EIF4A2,JMJD1C,ELP3,ARID5B,SMARCD3,PRDM1,EIF2A,ARID1A,SUPT5H,TCF7L2,MYBBP1A,KPNA1,HIF1A,ZNF254,TCF12,ID1,TRERF1,NPAS2,RBFOX2,PBX1,FOSL2,IGSF1,PAIP2,TERF2IP,NRF1,SOCS1,IKBKB,ETF1,MAML3,KAT8,KRT7,TFCP2,EIF3J,MTIF2,ATXN1,POU2F1,ERC1,EIF3H,SMAD3,VDR,RBBP8,ELP2,SMARCC1,KLF4,ARNTL,ATG7,MED20,MAPT,HMGA2,MAP3K13,TCF3,TRAK1,ID2,NFX1,IGF2BP2,ATF7IP,TRIM22,IKBKAP,RPS6KA5,BMP6,FOXO3,ABL1,TADA3,SNW1,PSMG4,SAMD4A,KDM5B,FOXN3,SMARCAD1,KDM5A,MEN1,POLR3G,SRCAP,NSD1,TBX3,SET,RBPJ,BMP4,NR2F2,DDIT3,KAT6A |
| 8.390e-06 | -11.69 | SET | pfam domains | PF00856 | 42 | 17 | 16629 | 2165 |
ASH1L,KMT2D,SETD1B,KMT2E,PRDM16,SETD2,EHMT1,PRDM1,KMT2C,SETD7,NSD1,EHMT2,SUV39H2,SETD5,KMT2A,SETD6,SMYD3 |
| 8.429e-06 | -11.68 | ductolobular_carcinoma | COSMIC cancer mutations | ductolobular_carcinoma | 1676 | 273 | 17775 | 2278 |
ADAM19,THOC5,CACNA1H,CSPP1,UBR5,LPIN1,AMBRA1,PDZD2,SREBF2,C12orf76,AP1M1,KDM5C,SPAG6,ZNF646,NRAS,OSBP2,EHMT1,CUX1,RFX2,AKAP12,TMEM206,DDX3X,BRCA2,SH3RF1,RUNX1,SPOCK3,ZNF532,SYNPO,PTPN14,MEF2C,JUP,FAM189B,NHS,PIK3R4,TGFBR2,CDC73,CHD5,TECTA,PRKCE,EIF2S2,HR,CACNB2,PRPS1,PPA1,SIK3,KCNQ3,RREB1,RB1CC1,RAPGEF4,EIF4A2,RYR2,TTYH2,MAP7D1,ARID1A,PLCB1,EVI5,EHBP1,NCDN,ZNF425,SEC31A,GTF2A1,CLASRP,SPEN,SURF1,DPEP1,IQSEC2,RTTN,ABCA3,DDX18,OLA1,CD99L2,MYH9,STAM,FLNB,CHD7,BCAS2,WAC,SOCS6,C16orf58,NBEA,TTC3,LYST,ZCCHC14,RFC4,KMT2D,ZNF480,ARHGEF10,GALK2,FGFR1,BAZ1A,TAF2,ELP2,ASTN2,NSMCE2,DNAJA3,HOXA3,TRMT2A,RPS6KB1,FUS,BRCC3,PDCD11,YEATS2,TRIM36,SHQ1,BRAF,TCF3,RTN4,MLH1,IKBKAP,NEDD4,ABL1,PTRF,SUV39H2,SDCBP2,SPTAN1,NAV3,DIS3L2,PFKFB4,TTPAL,ERICH1,NXN,ETFDH,ZNF155,COQ9,ATM,CORO2B,ANAPC4,DDIT3,LRRC41,FEM1C,ATRX,NF1,PLOD1,RNF43,SLC29A1,BCOR,NLE1,CUTC,SMARCB1,ABL2,ZNF804A,AMPD3,SRSF2,LONRF2,ZNHIT6,SLC39A7,GPR87,ANKRD11,SF3A1,VPS13B,DBN1,FLNC,LAMA4,CHD9,DTNB,ZNF124,ANK2,TSN,ARRDC3,KSR2,BRCA1,MTHFD1L,LAMA2,KMT2C,KIF16B,TMEM132B,TCF7L1,HLCS,SUFU,TP53BP1,PER1,RLTPR,PQBP1,CSMD3,SLC12A7,SEPHS2,FN1,TAF1,XPO7,DNAH1,ARID1B,NAMPT,DOPEY1,MCAM,VPS72,ATXN2,SEMA3D,TIMELESS,WNT16,PRF1,N4BP2,KRT20,LAMC1,XPO5,JMJD1C,SETD2,HOMER2,TBXAS1,OBSCN,WWC1,PRDM1,TCF7L2,POP1,BICD1,DNAH17,EXOC4,DDX10,BCCIP,CYLD,PCNT,OLFM2,MMRN2,ARID2,MYO7A,TBCCD1,SMARCA4,SPATS2,PIBF1,RADIL,PLXNB1,ZSCAN5A,VPS18,CAD,SOCS1,LYPLAL1,NUP133,SNTG2,IKBKB,ZNF142,BCAP29,CPSF3,MET,MOSPD1,ACSL5,SKIV2L,EVL,SSFA2,POU2F1,VIM,TMEM123,NUP214,UBR4,WARS,SMAD3,ZNF436,ARC,PUS1,NFASC,HM13,SH2D3A,PPHLN1,CLSTN2,BMP6,HIST2H2AB,SACS,TMEM161A,DSG2,PKNOX1,TOP1,ADAMTSL3,PSPC1,TPM4,ASAP3,MEN1,GPNMB,PDE2A,HSPA1B,CTIF,CACNB1,GPC2,AGTPBP1,GLG1,HRH1 |
| 8.429e-06 | -11.68 | breast-carcinoma-ductolobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductolobular_carcinoma | 1676 | 273 | 17775 | 2278 |
ADAM19,THOC5,CACNA1H,CSPP1,UBR5,LPIN1,AMBRA1,PDZD2,SREBF2,C12orf76,AP1M1,KDM5C,SPAG6,ZNF646,NRAS,OSBP2,EHMT1,CUX1,RFX2,AKAP12,TMEM206,DDX3X,BRCA2,SH3RF1,RUNX1,SPOCK3,ZNF532,SYNPO,PTPN14,MEF2C,JUP,FAM189B,NHS,PIK3R4,TGFBR2,CDC73,CHD5,TECTA,PRKCE,EIF2S2,HR,CACNB2,PRPS1,PPA1,SIK3,KCNQ3,RREB1,RB1CC1,RAPGEF4,EIF4A2,RYR2,TTYH2,MAP7D1,ARID1A,PLCB1,EVI5,EHBP1,NCDN,ZNF425,SEC31A,GTF2A1,CLASRP,SPEN,SURF1,DPEP1,IQSEC2,RTTN,ABCA3,DDX18,OLA1,CD99L2,MYH9,STAM,FLNB,CHD7,BCAS2,WAC,SOCS6,C16orf58,NBEA,TTC3,LYST,ZCCHC14,RFC4,KMT2D,ZNF480,ARHGEF10,GALK2,FGFR1,BAZ1A,TAF2,ELP2,ASTN2,NSMCE2,DNAJA3,HOXA3,TRMT2A,RPS6KB1,FUS,BRCC3,PDCD11,YEATS2,TRIM36,SHQ1,BRAF,TCF3,RTN4,MLH1,IKBKAP,NEDD4,ABL1,PTRF,SUV39H2,SDCBP2,SPTAN1,NAV3,DIS3L2,PFKFB4,TTPAL,ERICH1,NXN,ETFDH,ZNF155,COQ9,ATM,CORO2B,ANAPC4,DDIT3,LRRC41,FEM1C,ATRX,NF1,PLOD1,RNF43,SLC29A1,BCOR,NLE1,CUTC,SMARCB1,ABL2,ZNF804A,AMPD3,SRSF2,LONRF2,ZNHIT6,SLC39A7,GPR87,ANKRD11,SF3A1,VPS13B,DBN1,FLNC,LAMA4,CHD9,DTNB,ZNF124,ANK2,TSN,ARRDC3,KSR2,BRCA1,MTHFD1L,LAMA2,KMT2C,KIF16B,TMEM132B,TCF7L1,HLCS,SUFU,TP53BP1,PER1,RLTPR,PQBP1,CSMD3,SLC12A7,SEPHS2,FN1,TAF1,XPO7,DNAH1,ARID1B,NAMPT,DOPEY1,MCAM,VPS72,ATXN2,SEMA3D,TIMELESS,WNT16,PRF1,N4BP2,KRT20,LAMC1,XPO5,JMJD1C,SETD2,HOMER2,TBXAS1,OBSCN,WWC1,PRDM1,TCF7L2,POP1,BICD1,DNAH17,EXOC4,DDX10,BCCIP,CYLD,PCNT,OLFM2,MMRN2,ARID2,MYO7A,TBCCD1,SMARCA4,SPATS2,PIBF1,RADIL,PLXNB1,ZSCAN5A,VPS18,CAD,SOCS1,LYPLAL1,NUP133,SNTG2,IKBKB,ZNF142,BCAP29,CPSF3,MET,MOSPD1,ACSL5,SKIV2L,EVL,SSFA2,POU2F1,VIM,TMEM123,NUP214,UBR4,WARS,SMAD3,ZNF436,ARC,PUS1,NFASC,HM13,SH2D3A,PPHLN1,CLSTN2,BMP6,HIST2H2AB,SACS,TMEM161A,DSG2,PKNOX1,TOP1,ADAMTSL3,PSPC1,TPM4,ASAP3,MEN1,GPNMB,PDE2A,HSPA1B,CTIF,CACNB1,GPC2,AGTPBP1,GLG1,HRH1 |
| 8.436e-06 | -11.68 | MILI_PSEUDOPODIA_HAPTOTAXIS_UP | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_UP | 492 | 97 | 17758 | 2279 |
TCF12,RWDD1,PAPD4,ATRX,PAFAH1B1,OLA1,DDR2,SBF2,ZMAT2,RAP1A,IDI1,ERI1,UCHL5,ANKRD11,HIBCH,SSBP1,MTHFD2L,CDK12,TMLHE,PHLDB2,PDK1,EIF3J,GMFB,NFIA,R3HDM1,MRRF,CAMSAP2,DKC1,SETD7,MAK16,FKBP3,YTHDF2,CAMK2D,RBBP8,KPNA3,HNRNPR,LSM14A,BEND6,BMI1,TROVE2,DCAF5,WDR75,ESCO1,UTP14A,CENPB,PPHLN1,WDR26,IGF2BP2,OPA1,PDCD5,INPP1,PIP4K2A,MBNL1,NAMPT,PTPN2,RSPRY1,TTC1,EIF2S2,CFDP1,TANK,ZNF326,LTN1,SELT,SAMD4A,RANBP6,KIAA1143,AP4S1,STAG1,POLA1,PSMC3IP,EIF2A,PALLD,EIF5B,MBNL2,USP46,CENPP,TSR1,MPP7,HIF1A,HNRNPH3,SNAP23,AGTPBP1,CUL2,ZBTB12,RNF138,RIOK3,ZCCHC6,CDKAL1,ZRANB2,NCOR1,IQSEC2,PTP4A2,DDX10,FNBP1L,RABEP1,GPATCH4,ANAPC4 |
| 8.658e-06 | -11.66 | TERF2 (telomeric repeat binding factor 2) | protein interactions | 7014 | 249 | 61 | 16036 | 2270 |
BANP,BCKDK,RBM33,TFIP11,OSBPL9,MYH9,PLOD1,SEC16A,PABPC4,RING1,EDC3,ZC3H13,TOX4,TERF2IP,DST,CHD7,RNF40,SUB1,SLX4,ARMC6,DHX37,ACD,LDOC1L,DHX33,TMSB10,ANXA5,FBL,PRMT5,SRRM2,CARM1,TERF2,CDC37,PAXBP1,APEX1,DDX24,MYO10,SKIV2L2,ZC3H18,PCMT1,TOP3A,RYR2,BRCA1,DKC1,SAP30BP,RPA1,TAF2,DDX3X,FBXO21,GTF2A1,CLASRP,CCNT1,EEFSEC,CDK9,SET,TBPL1,H2AFX,ATM,MYOM2,NFRKB,BMI1,USP15 |
| 8.675e-06 | -11.66 | AA_TRNA_LIGASE_II | prosite domains | PS50862 | 17 | 10 | 11866 | 1504 |
NARS2,FARSA,EPRS,SARS,GARS,NARS,HARS,FARS2,HARS2,TARS |
| 8.886e-06 | -11.63 | Late Phase of HIV Life Cycle | REACTOME pathways | R-HSA-162599 | 127 | 36 | 8202 | 1117 |
CHMP2A,TAF1,GTF2H2C,VTA1,AK6,NUP43,NUP160,POM121,ELL,NUP133,TAF3,GTF2H1,RAN,SEH1L,GTF2H3,VPS37A,RNMT,TCEB3,RANGAP1,SUPT5H,NELFA,NUP214,UBC,POLR2A,TAF9B,TAF2,RANBP2,SUPT4H1,GTF2A1,CCNT1,CDK9,VPS37B,TAF4,NCBP2,TAF12,CHMP4C |
| 9.142e-06 | -11.60 | positive regulation of gene expression | biological process | GO:0010628 | 1690 | 278 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,GABPB2,LPIN1,NOS1AP,SKI,SREBF2,ZFHX3,RNF111,ZNF148,MEIS3,CDK6,DDN,HMBOX1,NR6A1,GNL3,NFIA,TCEB3,CUX1,SUPT20H,SLC50A1,DDX3X,BRCA2,SUPT4H1,CCNT1,RUNX1,RFXAP,MEF2C,BANP,DROSHA,EGR1,JUP,KHDRBS1,SIRT7,PID1,RSF1,PDCD5,CDC73,RBM20,MYC,MED24,PABPC1,TERF2,MYB,GTF2H3,BDNF,WDR61,STAG1,RREB1,PRDM16,ARID5B,SMARCD3,ARID1A,NELFA,PLCB1,TRIM37,ONECUT2,ABCF1,CAT,TASP1,HIF1A,CDK9,SPEN,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,MYH9,FOSL2,HSPA1A,BLOC1S2,TERF2IP,WAC,LPIN2,DTNBP1,KMT2A,KMT2D,BRD4,SATB2,MED16,MEF2D,SETD7,ERC1,SERP1,VDR,TAF2,SMARCC1,HIPK2,RPS6KB1,HMGA2,INSIG2,BRAF,TCF3,ID2,GAS6,TRIM22,TGFB2,RPS6KA5,FOXO3,MAD2L2,SFR1,TADA3,SNW1,TRIAP1,RDX,YBX3,LARP4B,SAMD4A,SOX6,MBTPS2,SLC40A1,FGF9,IL6R,KLF6,GUF1,FOXC1,UBC,POLR2A,NSD1,ARID3B,BMP4,IGBP1,UQCC1,DDIT3,KAT6A,TRIM16,ATRX,KMT2E,GPBP1L1,AAMDC,PPARGC1B,SIRT2,HNRNPLL,MAP2K3,SMARCB1,PHF5A,DHX33,ZEB1,RELB,RAN,ETV1,TRIM14,SRPK2,ZBTB17,DEAF1,TRIM13,ATF4,RBCK1,PPARG,ANK2,CDK4,HSPA5,BRCA1,CAV1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,TNFRSF1A,DLX2,CLU,ZC3H8,UQCC2,FOXO1,FN1,TAF1,PAX2,SMAD7,NKD2,TRIM15,ZIC2,BARX2,RLF,ARID1B,RHBDD1,NAMPT,SUB1,ELL,CEP290,BUD31,CTR9,GTF2H1,ICE2,WNT16,NRIP1,CAMKK2,PAXBP1,UTP15,PRDM1,EIF2A,SUPT5H,TCF7L2,ATXN7,IRAK2,ZFP90,TBL1X,TESC,TCF12,DLL4,ASH1L,ID1,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,NRF1,RRN3,JAG1,CAMTA2,IKBKB,MET,MAML3,PRPF19,MOSPD1,KAT8,DDX41,C1QTNF1,GRHL3,ATXN1,VIM,ZC3H12A,SMAD3,IKZF4,SIX5,KLF4,COPS5,CEBPZ,ARNTL,PUS1,HEATR1,DNAJC2,MAP3K13,SUPT6H,CAMK1,AGO2,ATF7IP,BMP6,PRKCH,HAS3,CD44,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,FGF2,ZNF821,KDM5A,SMARCAD1,MEN1,PIK3CB,HSPA1B,MKX,RERE,TBX3,TAF4,BCAS3,CSRNP1,NCBP2,MYRF,TAF12,RBPJ,NR2F2,NFKBIB |
| 9.314e-06 | -11.58 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN | 188 | 46 | 17758 | 2279 |
ADAM19,ATP6V1A,PAFAH1B1,TBCCD1,WDR37,NUP160,NOP56,RRN3,DECR1,EIF2S2,CEP290,TANK,SLC39A7,BUD31,LTN1,MAP3K14,VOPP1,IFRD1,LAMC1,SLC38A1,HARS,LSM12,PSPC1,ANKMY2,EIF4A2,VSNL1,MINA,KLF6,RBM28,UBE2K,SAP30BP,MAT2A,NSD1,ALG5,KPNA1,CDC16,SRRD,TIMM17A,SNAP23,ARHGAP12,SENP3,TAF12,APAF1,RNF130,SETD6,NMD3 |
| 9.350e-06 | -11.58 | ARM-type_fold | interpro domains | IPR016024 | 340 | 72 | 18293 | 2341 |
RTTN,CUL7,NF1,ARID2,AP1B1,NBEAL1,TTI1,GBF1,PELP1,URB1,ARMC6,THADA,ARMC5,FMNL1,PDS5B,NBEA,SPAG6,IPO11,LYST,FMNL3,C1orf228,AP4B1,PACRGL,C10orf76,UBR4,PUM3,ARMC4,TAF2,TRRAP,KPNA3,CEBPZ,HEATR1,SMG1,MIF4GD,JUP,PIK3R4,MON2,XPO7,BZW2,TMCO6,RSPRY1,CTNNBL1,INTS7,TNPO3,LTN1,UPF2,NOC3L,FMNL2,NOM1,IFRD1,RANBP6,STAG1,WDFY3,TANGO6,XPO5,RAP1GDS1,ZNFX1,ARID1A,SYMPK,PIK3CB,VAC14,NCDN,ARMC3,CTIF,INF2,KPNA1,MYBBP1A,AGTPBP1,SIL1,ATM,XPO6,IPO4 |
| 9.363e-06 | -11.58 | UTP18 (UTP18 small subunit (SSU) processome component) | protein interactions | 51096 | 13 | 9 | 16036 | 2270 |
NIFK,MPHOSPH10,SIRT7,CSNK2A1,RNF2,RBM19,FBL,USP36,NOP56 |
| 9.540e-06 | -11.56 | aa-tRNA-synth_II | interpro domains | IPR006195 | 17 | 10 | 18293 | 2341 |
NARS2,FARSA,EPRS,SARS,GARS,NARS,HARS,FARS2,HARS2,TARS |
| 9.626e-06 | -11.55 | CAND1 (cullin-associated and neddylation-dissociated 1) | protein interactions | 55832 | 665 | 134 | 16036 | 2270 |
ZNF76,CUL4A,NAT10,PLOD1,SEC16A,PABPC4,SMARCB1,SRSF2,CMSS1,RPS16,SRRM2,FTSJ3,CARM1,SF3A1,SRPK2,SNU13,RNMT,SKIV2L2,GNL3,HSPA5,DCUN1D5,HIST1H2BL,MCM2,RBM28,YTHDF2,DDX3X,TMCO1,LUC7L3,PRPF4,USP15,CARS,FN1,KHDRBS1,HSD17B10,PRPF39,SSR4,PHGDH,ARID1B,YARS2,IGF2BP3,DDX56,EIF2S2,ATXN2,ZNF326,VAPB,CCDC124,IGF2BP1,PABPC1,SERBP1,EXOSC2,MYO10,ARID5B,ISG15,PHF6,POP1,PWP1,ASCC3,TSR1,MYBBP1A,KPNA1,SYNCRIP,RPL28,PMEPA1,SRP68,C7orf50,DDX10,SRP14,AGO3,DDX18,LAGE3,SMARCA4,RSL1D1,SAFB2,MCM9,HNRNPA3,HSPA1A,NOP56,RPP30,MRPS27,SSBP1,PRPF19,GARS,AKAP8L,GLTSCR2,SFSWAP,PCMT1,DKC1,DSP,DHX57,PES1,SMARCC1,HNRNPR,COPS5,SCARB1,FUS,USP11,BRCC3,PDCD11,NIFK,AGO2,SF3A3,IGF2BP2,JMJD6,OPA1,ZNF346,NOP16,SEC24C,SHMT2,DDX31,POLR1B,CPNE7,YBX3,RPL22L1,HNRNPM,TOP1,FAM98A,DDX24,LSM12,LDHA,HIST1H4J,LENG8,ZNF407,C8orf33,EIF5B,NOP58,POLR2A,UBC,HSPA1B,TOE1,DDX50,HNRNPH3,CUL2,EIF2S1,NCBP2 |
| 9.793e-06 | -11.53 | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | MSigDB lists | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | 557 | 107 | 17758 | 2279 |
KCTD7,CYP24A1,PTP4A1,ZNF706,ADAM19,DLL4,LIN28B,PAPD4,CELSR3,UBN1,PPARGC1B,TNXB,ADAMTS6,NECAP1,BCOR,FAM13A,LCLAT1,SEMA6A,EDC3,CHD7,ZNF608,SOCS1,PPID,SLC38A2,JOSD1,SEH1L,LYST,SAP30,SOBP,ZCCHC14,RNMT,HSPA5,R3HDM1,ATXN1,SATB2,PNN,C10orf76,MARCH6,SOX4,SON,FKBP3,RAB10,MAT2A,BSN,GZF1,CAMK2D,AHNAK,KPNA3,LMBR1L,SH3RF1,WDR7,LARGE,HIC2,ADAM9,ASB3,RUNX1,NRP1,TNRC6A,LPP,TMCC1,ZNF507,KLHL24,CARS,HERC2,NCOR2,SSH2,INSIG2,ESCO1,ANKRD17,DLGAP4,NHS,CSNK1A1,GIGYF2,FAM49A,NEDD4,DDIT4,PTPN2,ABL1,ELL,CACNB2,GTF2H1,COPS7B,CLDND1,NRIP1,MAP3K12,NT5E,VOPP1,CAMKK2,RAPGEF4,ARID5B,RAP1B,PHACTR2,MEX3B,PRDM1,MBNL2,NAALADL2,PHF6,DAGLA,IRS1,ASCC3,BAZ2B,TASP1,KIAA0355,SPEN,CUL2,CNOT6,SH3PXD2A |
| 9.847e-06 | -11.53 | oesophagus-lower_third-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-adenocarcinoma | 6579 | 936 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,CACNA1H,TUBE1,SBF2,CSPP1,HLTF,CHAC1,HMOX2,NUP160,SYNJ1,AMBRA1,ZNF37A,TOM1L1,PDZD2,SREBF2,IKZF5,ZFHX3,NSRP1,THAP4,RASSF3,AP1M1,MAD1L1,PDS5B,WIZ,ZNF148,AVEN,SRRM2,CNTNAP3B,CCDC57,NRAS,PTPRM,EXOC6B,GNL3,EHMT1,KIF15,WDHD1,AKAP12,ABCC2,C10orf76,RBM28,SLC9A5,ZNF197,SLC7A1,AHNAK,BRCA2,MPV17,DIRAS1,RUNX1,P2RY11,HERC2,EP400,EPM2AIP1,TMEM63C,SIRT7,TRIO,BTBD9,RSF1,PDCD7,PITPNM1,YARS2,ABCA7,SLC39A11,RSPRY1,SH2B3,C6orf48,DHX37,INTS7,CACNB2,COQ3,ZNF518B,MAP3K12,PABPC1,PPA1,SERBP1,ANGPT2,MYB,NOM1,RABEPK,KLRD1,BDNF,GTF2H3,COL17A1,STAG1,KCNQ3,MYO10,RB1CC1,TYW1,EIF4A2,RYR2,USP10,ST6GALNAC3,IMPDH2,CPT1A,TRIM37,MBNL2,ONECUT2,NCDN,RDH11,IRS1,DYNC1H1,VPS13C,LRP1B,TASP1,KPNA1,TRAP1,SURF1,ZNF160,KIAA0196,WDR33,PDLIM5,MB21D2,ARHGAP10,SGSM3,SPRED2,ABCA3,ATP6V1A,BTBD2,DDR2,MYH9,AGAP6,ISG20L2,TUBB6,ST3GAL6,SAFB2,ZMAT2,EEA1,PRKD3,ESAM,SPG21,ABCA12,SETD5,FMNL1,C16orf58,INTS12,MSH4,ZC3H3,DENND1A,LYST,PMS1,GARS,KMT2D,KRT7,STAMBP,ZNF480,PI4KAP2,ARHGEF10,SLCO6A1,LGALS1,ADAM32,ATP6V0A1,MEF2D,KCNH3,DSP,VPS53,FGFR1,PDE8B,SLC39A14,PES1,TAF2,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,POLR3E,WDR7,HOXA3,RPS6KB1,FUS,ANKS1A,LAMA5,CEP170,CATSPERG,TRIM36,MORC2,SERINC5,XPC,SESTD1,XRRA1,WDR37,ATG2B,AKT1S1,IP6K2,TRIM22,TGFB2,MBNL1,KRI1,NOP16,UNC13A,ANXA5,LTN1,ACTR3B,SOX6,HNRNPM,LYPLA2,SPTAN1,FAM98A,ERICH1,LSM12,ZC3H18,FRA10AC1,NXN,RSBN1,R3HDM2,ZNF467,PDE3B,CASC1,CCDC150,SRCAP,BAZ2B,PXDN,ARID3B,BMP4,SORCS2,MTMR1,ANAPC4,KDM4C,CYP24A1,CUL7,BCAS4,GPBP1L1,PPARGC1B,TFIP11,POLR1A,SLC25A21,CSNK2A1,RNF43,FAM13A,TMEM132A,SEC16A,SCAF8,ABL2,AMPD3,ECM1,SRSF2,ARHGAP18,COPS4,MARVELD2,ANKRD11,METTL8,PPCDC,TRIML2,UBAP2L,ZNF85,RAN,ZNF3,ETV1,SLC25A23,FAM184A,PTPRK,VPS13B,METTL1,FLNC,DSC3,CHD9,SLC3A2,ABCC4,SKIV2L2,KATNAL1,ANK2,MED27,NOL6,GMFB,ATG12,LAMA2,ODC1,ZNF91,CRYBG3,LSG1,PEX1,KIF16B,BSN,GLS,HPRT1,LSS,TP53BP1,CHD3,EEFSEC,TECPR2,CCDC146,SOCS4,AHNAK2,ADAM9,PPP3CC,MAGI1,RNF214,USP15,MCM6,NKD2,FAN1,BARX2,TRIM15,RLF,ARID1B,DNAH1,SPIRE1,DOPEY1,ABCA5,CEP290,PDE10A,GTF2H1,TIMELESS,CTR9,SYNJ2,WNT16,GMDS,LRSAM1,CWF19L2,SNX29,TRAPPC9,LAMC1,IFT43,UTP15,OBSCN,ZNFX1,MAPK1IP1L,METTL22,SUPT5H,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,SPAG9,SYNCRIP,PALB2,DNAH17,ZNF430,CASS4,DTD1,ARHGAP12,DDX10,SH3PXD2A,TESC,RNF114,USP7,SART1,ID1,CYLD,OLFM2,PAPD4,SUCLG1,ARID2,NTSR1,RNF24,ZNF83,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PAG1,PLXNB1,KDM1A,CAD,ZNF608,ANKRD13A,NRF1,IDI1,NUP133,UBR1,FSIP2,CCDC40,ZFP37,ANO8,CORO1A,AKNAD1,IPO11,CASP10,CTC1,PRPF19,SOBP,SEC24A,WDR36,EVL,KIRREL2,THSD4,TMEM123,AKAP13,EIF3H,USP36,BTBD11,EXO1,RANBP2,RBBP8,LMBR1L,SIX5,ATG7,INTS9,ZNF18,NFASC,PUS1,EIF2B3,MUTYH,PARD3,ATXN7L2,UNC13D,ESCO1,MAP3K13,FAM46B,POGZ,BZW2,IQGAP2,SLC25A20,TTC1,ADH5,SACS,ANXA7,IFIT5,PRICKLE2,DDX31,POLR1B,CPNE7,PCK2,C12orf4,AP4S1,ADAMTSL3,LRRIQ1,FOXN3,SMARCAD1,KRTCAP3,TEX14,TOP3A,DHX34,PEAR1,FERMT2,RAP1GDS1,ARHGEF12,C11orf49,RANGAP1,PALLD,RHOT2,PIK3CB,ARMC3,NEU1,POLR3A,MKX,POLR3G,ZRANB3,CENPP,DKK1,TPD52L2,SRBD1,GPC2,L3MBTL3,ZBTB8OS,TAF4,SET,CSRNP1,BCAS3,FNTB,RBM26,RBPJ,TAF12,RPS6KC1,XPO6,KIF1B,ZNF292,MYCBP2,PLRG1,ENAH,NBEAL1,PRKCA,UBR5,GABPB2,LPIN1,GIPR,RNF111,VPS52,CHD2,FUT11,SEH1L,ZNF646,DDN,ACADS,SLC38A6,GDAP1,DPF3,NR6A1,ATG9A,C2orf76,NOL8,EYA3,CUX1,VSNL1,TCEB3,SEMA3F,CAMSAP2,SON,DENND4A,FOXRED1,DDX60,PLCXD2,GNAI1,OSBPL1A,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HIC2,VPS13D,DNAH2,NRP1,BMI1,ZMAT3,NMD3,SYNPO,SPOCK2,SPOCK3,EFNB2,PRPF38B,WDR75,JUP,CELSR1,ANKRD17,ZHX3,LARS2,PRPF31,DLGAP4,OPHN1,PID1,CCDC47,TGFBR2,CD226,MTUS1,IGF2BP3,PRKCE,TECTA,NAV1,SLC7A11,SCAF1,LDOC1L,SAMD13,GTF3C3,FDFT1,USE1,SCAF11,EXOSC2,RREB1,PRIM2,PCCA,RAPGEF4,PTPN12,ARID1A,PLCB1,EHBP1,SLC26A11,ARIH2,ATP9B,DAGLA,ZNF425,EPRS,ASCC3,KIDINS220,ALKBH3,VCAN,SPEN,SRP68,ZZEF1,RIOK3,NCOR1,CNDP2,MAP2K4,SMYD3,VMA21,RTTN,TRPM2,LIN28B,BIRC6,URB2,HFM1,KIAA0232,NDUFB5,PTPRG,SLC25A44,PABPC1L,IGSF1,PDE3A,PHC2,FLAD1,ZNF827,ARMC6,UCHL5,LPIN2,MRPS27,DTNBP1,SHF,NBEA,TTC3,PNPLA4,KMT2A,CDK12,NAA35,CASP8AP2,BRD4,GON4L,PDK1,MTIF2,PREX1,SATB2,MARCH6,PNN,MEGF11,MED16,GALK2,TBC1D16,STK10,DHX57,SNCA,VDR,HTR7,BAZ1A,SMARCC1,ZNF236,LARGE,ACP1,IFT140,SLC4A7,MDN1,PDCD11,SETD6,NOLC1,NCOR2,CA11,B4GALT5,ZNF280C,KIF5C,SLC25A12,FARS2,MYNN,MLH1,LIAS,OPA1,IKBKAP,FOXO3,FAM8A1,PHLDA2,NEDD4,ABL1,ZNF483,COMMD9,PTRF,NEBL,NISCH,DYNC2H1,CELF1,ERRFI1,LARP4B,NAV3,CLK2,TMC7,TSHZ1,SLC40A1,TTLL5,WDFY3,TMEM126B,KCNMA1,BMS1,GUF1,SLC23A2,RETSAT,FBXO21,INF2,ZDHHC11,HELZ,COQ9,STX18,ATM,SVIL,MYOM2,APAF1,NDUFS5,PGAM5,ADK,IPO4,LRRC41,PIGM,NF1,ATRX,RARS2,KIF5A,FANCD2,TRPM6,ZNF107,PLOD1,SLC29A1,BCOR,CUTC,AHCYL2,SLC30A7,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,LONRF2,GPR87,IPP,ZEB1,GPATCH1,JOSD1,PCOLCE2,SLC27A5,HCFC2,TRIP13,CEP128,SRPK2,TIMM50,ZBTB17,DTNB,TNK2,DEAF1,FBXW4,SKAP2,ZNF195,SLC38A1,CMIP,VWCE,MINA,KSR2,CAV1,MTHFD1L,KMT2C,TCTN1,SERGEF,TIMM44,CCDC3,UBTF,TMEM132B,GEMIN5,EIF4ENIF1,GATA6,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,GALNT10,COPS6,DCAF5,DMTF1,TNRC6A,VIPR1,SLC12A7,CHST11,FN1,ZCCHC8,VTA1,PAX2,PCSK7,MED13L,SMG7,EVPL,QSER1,PHGDH,ETFB,SIPA1L3,HVCN1,MCAM,ATXN2,WDR27,CCDC112,SEMA3D,PRF1,ZCCHC7,NRIP1,LRP3,POLR1E,AKAP11,N4BP2,CPSF3L,MTHFD1,RANBP6,KRT20,PPAT,TRA2A,XPO5,ELP3,ZBED4,JMJD1C,TBXAS1,WWC1,C11orf65,EIF2A,CORIN,AGAP1,C19orf70,EXOC6,POP1,SYCP2L,UBAP2,ATAD5,KIAA0355,FAT1,SDCCAG8,EXOC4,HK2,CDKAL1,KIAA1328,PFDN2,TBCK,C7orf26,DMXL2,FEZ2,ASH1L,PCNT,CELSR3,SLC5A5,TNXB,SMARCA4,COBLL1,PIBF1,GBF1,DHX35,SLC39A1,ZSCAN5A,ZC3H13,VPS18,RRN3,BRE,MPHOSPH10,CAMTA2,PPFIBP1,SNTG2,ZNF142,MET,ITGAX,TSPAN14,ZNF460,GNG5,MAML3,MCEE,ACSL5,NARS2,NPW,ANTXR2,PRAME,PHLDB2,PARP2,NLN,ATXN1,DKC1,ATP8B2,UBR4,TPK1,ARMC4,ADNP,CEBPZ,ARNTL,FKBP5,DISP1,NFRKB,BRD9,SMG1,KLHL24,DNAJC2,SUPT6H,CAMK1,KLC4,PDE4B,VPS45,DBF4,CLSTN2,IGF2BP2,ATF7IP,SEMA3E,CCDC7,SOGA1,MFHAS1,GFM2,PIP4K2A,MFSD10,MAN1A1,PRKCH,PEX7,GART,CTNNBL1,SEC24C,TANK,STC2,KDELC1,TTC17,LDLRAD3,ERI3,DMRT1,MICAL3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,MSX1,DNMBP,CRIM1,PSPC1,TEAD1,PPP1R21,ASAP3,ZNF324B,PHACTR2,ARHGAP32,MEN1,EIF5B,NAALADL2,TARS,RERE,ZNF221,ZNF708,ALG5,DAGLB,SERINC1,WDR35,MPP7,AGTPBP1,ZNF330,CUL2,NCBP2,MBD6,PREPL,TATDN1,NFKBIB,POLR1C,MMP16,ZAK,ARHGAP27 |
| 9.897e-06 | -11.52 | regulation of cellular response to stress | biological process | GO:0080135 | 620 | 118 | 16441 | 2138 |
SPRED2,THOC5,CUL4A,FEZ2,PAFAH1B1,NPAS2,TNXB,RIPK1,RSL1D1,GRINA,NUP43,NUP160,UBR5,HSPA1A,KDM1A,AMBRA1,TERF2IP,BRE,NEK6,SREBF2,PMAIP1,NUP133,DNAJB6,WAC,DTNBP1,MET,SPIDR,OGG1,CDK6,HTRA2,SEH1L,ZBTB17,TRIM13,BRD4,ATF4,SIRT6,RAB7A,HSPA5,EYA3,MCL1,BRCA1,CAV1,EDEM2,NUP214,USP36,SPOP,SNCA,TAF9B,PYCR1,SKIL,RANBP2,CAMK2D,ZNF622,SH3RF1,NSMCE1,PER1,HIPK2,ARL6IP5,COPS5,ARNTL,ATG7,H2AFX,DUSP19,CLU,BRCC3,MID1,BAG1,HMGA2,DNAJC2,WDR75,TNIK,MINK1,BRAF,FOXO1,UBXN1,MAPK8IP3,AKT1S1,TGFB2,OPA1,RNASEH2B,NOL3,PIP4K2A,POM121,PTPN2,ABL1,TMEM161A,MYC,TRIAP1,WNT16,YBX3,CD44,LRSAM1,TERF2,HMGCR,ZNF675,MSX1,APEX1,WDFY3,MEN1,SUPT5H,PLCB1,HERPUD1,POLR3A,RPA1,HSPA1B,SPAG9,RPL28,GADD45A,TRAP1,HIF1A,CDK9,ATM,PSAP,NCOR1,IGBP1,BRSK2,ZAK,DDIT3 |
| 9.925e-06 | -11.52 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN | 194 | 47 | 17758 | 2279 |
SRM,CARS,POLB,POLR1A,OLA1,JMJD6,CHCHD10,RNASEH2B,DCTPP1,CAD,DECR1,POLR3D,IDI1,NVL,MCM5,PDS5B,ALDH18A1,PPA1,TRIP13,CARM1,ELOF1,FDFT1,METTL1,RFC4,DDX41,PRIM2,MINA,MRPS10,BRCA1,MCM2,CYB5B,TRIM37,TAMM41,TPD52L2,MTHFD2,LUC7L3,SYNGR2,HK2,XPNPEP1,CRCP,NCBP2,HMBS,RBPJ,NDUFS5,DHCR7,BLMH,GCSH |
| 9.994e-06 | -11.51 | CAGCTTT,MIR-320 | MSigDB lists | CAGCTTT,MIR-320 | 251 | 57 | 17758 | 2279 |
BANP,SPRED2,ATP6V1A,NPAS2,RHOBTB1,ATRX,TNFRSF21,ZNF280C,MAPK8IP3,PCSK7,SMG7,ENAH,BHLHE40,GABPB2,POGZ,IGF2BP3,FKBP1A,METTL16,ANKRD13A,RAP1A,ABCA12,NSRP1,TRMU,CALN1,ZNF3,CDK6,SERBP1,DBN1,SOBP,MSI2,PCGF3,EIF3J,FOXN3,KDM5A,ARID5B,CUX1,ATXN1,MEX3B,CAMSAP2,SATB2,MCL1,PALLD,SON,NCDN,MAT2A,NAP1L5,TPD52L2,HELZ,RAD18,SH3RF1,VPS37B,PURB,USP20,RUNX1,NRP1,MMP16,TROVE2 |
| 1.002e-05 | -11.51 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | biological process | GO:0000377 | 248 | 57 | 16441 | 2138 |
SART1,ZCCHC8,PRPF31,TFIP11,PLRG1,SF3A3,PPIL1,PDCD7,NOL3,PRPF39,ZMAT2,DHX35,RSRC1,HNRNPA3,UBL5,MBNL1,SNW1,SRSF2,BCAS2,PHF5A,CTNNBL1,CWC27,BUD31,GPATCH1,CELF1,GEMIN4,CPSF3,PRMT5,SRRM2,PABPC1,HNRNPM,SRPK2,PRPF19,SF3A1,SCAF11,SNU13,PTBP2,DDX41,SKIV2L2,USP49,TRA2A,PSPC1,PNN,CLNS1A,POLR2A,GEMIN5,PRPF40B,SYNCRIP,HNRNPR,SPEN,LUC7L3,HNRNPH3,PQBP1,NCBP2,PRPF4,FUS,PPIL3 |
| 1.002e-05 | -11.51 | mRNA splicing, via spliceosome | biological process | GO:0000398 | 248 | 57 | 16441 | 2138 |
SART1,ZCCHC8,PRPF31,TFIP11,PLRG1,SF3A3,PPIL1,PDCD7,NOL3,PRPF39,ZMAT2,DHX35,RSRC1,HNRNPA3,UBL5,MBNL1,SNW1,SRSF2,BCAS2,PHF5A,CTNNBL1,CWC27,BUD31,GPATCH1,CELF1,GEMIN4,CPSF3,PRMT5,SRRM2,PABPC1,HNRNPM,SRPK2,PRPF19,SF3A1,SCAF11,SNU13,PTBP2,DDX41,SKIV2L2,USP49,TRA2A,PSPC1,PNN,CLNS1A,POLR2A,GEMIN5,PRPF40B,SYNCRIP,HNRNPR,SPEN,LUC7L3,HNRNPH3,PQBP1,NCBP2,PRPF4,FUS,PPIL3 |
| 1.011e-05 | -11.50 | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_UP | 183 | 45 | 17758 | 2279 |
RTTN,VMA21,LYRM4,SPRYD7,PLRG1,TMEM109,GDPD5,ADH5,DDX56,GART,RAN,GEMIN4,PRADC1,PRMT5,CDK6,HSD17B12,SLC25A1,MBTPS2,RABEPK,SKIV2L2,HARS,WDR18,HAUS6,SLC35G1,TBRG4,KRTCAP2,GSTCD,ARL5B,TARS,POLR3G,YIF1A,SLC7A1,ALG5,YIPF2,TP53BP1,COPS5,ADAT2,USP20,NCBP2,PPP3CC,UMPS,TMEM101,EME1,DCAF5,GCSH |
| 1.017e-05 | -11.50 | GENTILE_UV_HIGH_DOSE_DN | MSigDB lists | GENTILE_UV_HIGH_DOSE_DN | 304 | 66 | 17758 | 2279 |
PHF3,ID1,PAFAH1B1,RIPK1,SLC25A44,FOSL2,STAM,PHC2,PMAIP1,MET,RFC4,PCGF3,TRIM13,MCL1,SATB2,PNN,PITPNB,MAT2A,GNAI1,UBTF,SMAD3,DDX3X,ADNP,LSM14A,TNFRSF1A,DLX2,RUNX1,BMI1,HMGA2,ZHX3,PRSS3,SMAD7,PDE4B,ID2,JMJD6,BHLHE40,CLINT1,TGFBR2,POGZ,SFI1,POM121,IGF2BP3,DDIT4,MLX,NOP16,MBD2,NRIP1,SAMD4A,NAV3,EXOSC2,BDNF,IFNGR2,ZBED4,ARID5B,FERMT2,USP10,PTK2,HERPUD1,ISG15,DKK1,RARS,GADD45A,POLE2,SPEN,TBL1X,DDIT3 |
| 1.028e-05 | -11.49 | MITOCHONDRION | MSigDB lists | MITOCHONDRION | 334 | 71 | 17758 | 2279 |
LETM1,SUCLG1,PDK4,MRPL10,HSPA1A,FDX1,DECR1,PMAIP1,ATP5G2,TRMU,NDUFA6,FXN,HTRA2,LONP1,TIMM50,ACADS,PDK1,MTIF2,CPOX,MSRB3,MCL1,CA5B,POLG2,FOXRED1,TMEM186,ATP5D,TIMM44,TAMM41,DNAJA3,TIMM17A,MPV17,BDH2,SLC25A11,FIS1,MTCH1,DMGDH,BCKDK,TRAK1,HSD17B10,SLC25A12,OPA1,TIMM10,NDUFS7,ETFB,MRPS11,NDUFV1,PTRF,TRIAP1,PMPCA,SHMT2,PCK2,NT5M,TOMM34,SLC25A1,NIPSNAP1,MTHFD1,TIMM8B,TMEM126A,ABCF2,BCS1L,MRPS10,TBRG4,CPT1A,RHOT2,HSPA1B,MFN2,MTHFD2,D2HGDH,SURF1,NDUFS5,GCSH |
| 1.036e-05 | -11.48 | chromatin | cellular component | GO:0000785 | 436 | 87 | 17570 | 2233 |
TCF12,ATRX,CSNK2A1,SMARCA4,SIRT2,TNKS1BP1,PELP1,RING1,KDM1A,SMARCB1,PHC2,SLX4,KDM2A,UCHL5,PDS5B,RNF2,RAN,HTRA2,TMPO,BRD4,SIRT6,BAZ2A,CDK4,HIST1H2BL,MCM2,ENC1,CHAF1A,SMAD3,TRRAP,SMARCC1,RAD18,HLCS,KLF4,E2F4,H2AFX,PUS1,NFRKB,EME1,ZC3H8,HMGA2,EP400,ESCO1,ANKRD17,TCF3,DPF2,SIRT7,H2AFJ,CHD5,HIST2H2AB,POGZ,NEDD4,SFR1,TOX4,RNF40,ELL,SNW1,POLR3D,SUV39H2,MBD2,BUD31,TIMELESS,CTR9,HIST2H3D,ICE2,EXOSC4,NRIP1,GATAD2B,TRNP1,STAG1,WDR61,SMARCAD1,POLA1,SMARCD3,APTX,HIST1H4J,ARID1A,MEN1,PLCB1,FOXC1,TCF7L2,POLR3G,EHMT2,BCAS3,NCOR1,KDM4C,IPO4,KAT6A |
| 1.043e-05 | -11.47 | P-loop_NTPase | interpro domains | IPR027417 | 853 | 152 | 18293 | 2341 |
ATRX,KIF5A,DDX19A,HLTF,RAC3,SRPRB,CMSS1,RAP1A,YLPM1,DHX33,XRCC2,MYH3,CHD2,RAN,TRIP13,LONP1,CHD9,NRAS,ABCC4,SKIV2L2,KATNAL1,GNL3,KIF15,ABCC2,MTHFD1L,MCM2,DDX60,LSG1,GNAI1,PEX1,KIF16B,RHOU,DDX3X,ZGRF1,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,DNAH2,DIRAS1,MAGI1,EP400,AK2,MCM6,RHOBTB1,AK6,CHD5,DNAH1,ABCA7,DDX56,NAV1,DHX37,ABCA5,MCM5,CACNB2,N4BP2,MTHFD1,DDX28,MYO10,EIF4A2,RAP1B,BCS1L,ZNFX1,AGAP1,ABCF1,DNAH14,DYNC1H1,ASCC3,ATAD5,NSF,RRAGA,GPN1,DDX10,N4BP2L2,HS2ST1,DNM3,ABCA3,DDX18,ATP6V1A,HFM1,MYO7A,OLA1,SMARCA4,MYH9,DHX35,MCM9,CBWD5,DDX60L,CHD7,NUBPL,ABCA12,NVL,MYH15,MSH4,CMPK1,SKIV2L,RFC4,RFC3,MPP6,DDX41,RAB7A,MTIF2,DLG4,GNL1,ARL5B,RAB10,DHX57,RAD54B,ARL13B,CBWD1,MDN1,SEPT5,RAB30,VWA8,SULT1C2,ARL15,C10orf2,KIF5C,OPA1,GFM2,MFHAS1,IQGAP2,CBWD6,DDX31,DYNC2H1,NAV3,PFKFB4,DDX24,LRRIQ1,ZFYVE1,SMARCAD1,ABCF2,SULT4A1,DHX34,BMS1,EIF5B,RHOT2,GUF1,DDX49,MMAA,MFN2,ZRANB3,SRCAP,CACNB1,DDX50,HELZ,MPP7,ORC5,MSH3,APAF1,KIF1B |
| 1.062e-05 | -11.45 | MARTINEZ_RB1_AND_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_DN | 558 | 107 | 17758 | 2279 |
GGT1,NDUFA5,RBFOX2,C16orf45,SMARCA4,SSBP2,CHAC1,SAFB2,AARS,UBL5,PDE3A,MGA,RIOK2,RRN3,IDI1,RASSF3,PPCDC,MYH3,ZNF148,MSH4,KIAA0922,MGLL,TRIP13,ACSL5,SKIV2L2,UPP1,CUX1,ATF7IP2,NFIA,MARCKSL1,MCL1,LAMA2,NHSL1,KRTCAP2,ENC1,ZDHHC14,SON,ERC1,CLNS1A,SNCA,SLC39A14,RHOU,VDR,MSX2,RBBP8,SH3RF1,G6PD,HIPK2,INTS9,HOXA3,FKBP5,CLU,LAMA5,TNRC6A,SEPHS2,TNNC1,WDR75,MIF4GD,FOXO1,SUPT6H,CLK1,NKD2,GTF2IRD1,PDCD7,FOXP1,SLC39A11,HR,UBE3A,TNPO3,CELF1,S100A14,ERRFI1,PRMT5,LPCAT1,SCAF11,CAMKK2,AP4S1,KDM5B,MYO10,CRIM1,LSM12,TLE3,ELOVL6,XPO5,RDH10,HOMER2,SCMH1,WWC1,CPT1A,PLCB1,FOXC1,NCDN,POLR3A,NR2F1,POLR2A,UBC,RDH11,PGD,MGAT2,EPRS,NME7,PMEPA1,SET,STX18,RIOK3,ATM,PURB |
| 1.093e-05 | -11.42 | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP | 167 | 42 | 17758 | 2279 |
PTP4A1,VIPR1,TTN,C9orf78,LETM1,EGR1,ITPRIP,RARS2,C10orf2,TNFRSF21,ID2,TIGD1,ABL2,PSMG4,FHIT,SOX6,SNX29,NOM1,CHD9,DDX28,IL11RA,TSPYL4,RAP1GAP2,CUX1,UTP15,MEF2D,ENC1,TTC28,ST3GAL5,TCF7L2,ARIH2,ANXA1,TMEM132B,NAP1L5,FBXL5,SKIL,ZDHHC11,GADD45A,L3MBTL3,KLF4,POLR3E,C7orf26 |
| 1.099e-05 | -11.42 | basal transcription machinery binding | molecular function | GO:0001098 | 27 | 13 | 16491 | 2164 |
PAF1,ELP2,ZNHIT6,ELP3,AGO2,WAC,ZNF326,CTR9,FBL,IKBKAP,CDC73,SMYD3,NOP58 |
| 1.099e-05 | -11.42 | basal RNA polymerase II transcription machinery binding | molecular function | GO:0001099 | 27 | 13 | 16491 | 2164 |
PAF1,ELP2,ZNHIT6,ELP3,AGO2,WAC,ZNF326,CTR9,FBL,IKBKAP,CDC73,SMYD3,NOP58 |
| 1.105e-05 | -11.41 | lung | COSMIC cancer mutations | lung | 17159 | 2232 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,ATF7IP,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,METTL23,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.141e-05 | -11.38 | small molecule metabolic process | biological process | GO:0044281 | 2269 | 360 | 16441 | 2138 |
GGT1,GNB3,PRKAB2,TNFRSF21,AARS2,CACNA1H,GYG1,NT5C3A,HMOX2,SLC6A8,PRKCA,NUP160,SYNJ1,AARS,LPIN1,CIAPIN1,SREBF2,ATP5G2,FAAH2,SUCLG2,ME1,FXN,PPM1K,CSGALNACT2,SEH1L,ACADS,UPP1,ALDH1L2,GNG7,OSBPL1A,STOML2,PYCR1,DDAH2,BDH2,TXN2,SPOCK2,SPOCK3,RBP1,CARS,LARS2,ST6GAL1,AK6,PIK3R4,PLA2G12A,NDUFS7,YARS2,PI4KB,ENTPD5,ATIC,SLC16A9,LPCAT1,AGL,COQ3,PRPS1,PPA1,FDFT1,HMGCR,FADS1,BDNF,AOC2,PCCA,RDH10,RAPGEF4,IDH3G,SMARCD3,SNAP25,IMPDH2,PLCB1,CPT1A,MTR,ANGPTL4,RDH11,CAT,DAGLA,EPRS,MTHFD2,GSTO2,NME7,HIF1A,VCAN,D2HGDH,SURF1,SQLE,DPEP1,PEX13,UMPS,BPNT1,NCOR1,CNDP2,MACROD1,DHCR7,CPT1C,HS2ST1,GALE,SDSL,TRERF1,PAFAH1B1,NPAS2,ATP6V1A,UROD,PDK4,NDUFB5,OLA1,NUP43,ST3GAL6,LCLAT1,HSPA1A,PDE3A,NDUFB3,FLAD1,DECR1,ASNS,PYCRL,LPIN2,GSTA4,NT5C,CMPK1,MTHFD2L,MGLL,GARS,PDK1,DLG4,ATP6V0A1,GALK2,SLC35D1,NUDT15,SERP1,MAT2A,HSD3B7,PDE8B,SNCA,GNG2,DCXR,G6PD,PEMT,MORC2,NOSTRIN,NCOR2,SERINC5,INSIG2,B4GALT5,MRI1,FARS2,SLC25A12,IP6K2,LIAS,RNASEH2B,INPP1,PSMF1,POM121,DCTPP1,GATC,NISCH,ACOT11,PHYKPL,HARS2,PTGS1,NT5M,LYPLA2,MBTPS2,PFKFB4,PSAT1,AGPAT4,LDHA,ADSL,PPIP5K2,PDE3B,MMAA,UBC,ECH1,SLC23A2,TRIB3,ETFDH,RETSAT,RARS,STX1A,COQ9,ACOX1,SRD5A3,NDUFS5,GPAM,PSAP,ADK,MTMR1,SRM,CYP24A1,LYRM4,MVK,RARS2,SLC52A3,CERS5,SLC25A21,PLOD1,COX10,AHCYL2,PCYOX1L,AMPD3,RAP1A,PHKA1,PPCDC,MYH3,HYAL1,RAN,NDUFA6,SLC27A5,YARS,OGG1,CARM1,MPST,PRKACB,CHD9,ATF4,SESN2,ITPA,HARS,PPARG,GPCPD1,COL4A3BP,PITPNB,BRCA1,CAV1,MTHFD1L,DLST,ODC1,ST3GAL5,MPC1,MGST1,GLS,LSS,HPRT1,MSRA,HLCS,INSIG1,TNFRSF1A,ABCC3,SEPHS2,XYLB,AOC3,SARS,CHST11,AK2,SEC24D,PRSS3,GPAT3,HSD17B10,PHGDH,ETFB,NAMPT,MLX,PDE10A,VAPB,GLTP,SYNJ2,ALDH18A1,PNPLA3,NT5E,MTHFD1,WARS2,PDE4A,PPAT,ELOVL6,TBXAS1,PSMA1,ACOXL,VAC14,TCF7L2,PGD,FDPS,TBPL1,HK2,SLC16A1,DTD1,HMBS,TBL1X,GGT7,PRKAR2A,PDE9A,PDSS2,NDUFA5,SUCLG1,SLC5A5,NDUFAF2,LPCAT2,CEMIP,SLC2A1,NTSR1,TNXB,LPCAT3,ARSJ,PUDP,FDX1,CAD,FARSA,IDI1,NUP133,CBR4,HIBCH,FHIT,AHCYL1,GNG5,TMLHE,MCEE,SEC24A,NARS2,ACSL5,NARS,CPOX,CA5B,NUP214,ATP5D,WARS,TPK1,PLIN2,RANBP2,ALAD,ABHD3,ATG7,SLC25A11,SCARB1,MUTYH,DMGDH,BCKDK,AUH,SULT1C2,PDE4B,TKFC,APRT,CHCHD10,VARS,PIP4K2A,SLC25A20,ADH5,PEX7,NDUFV1,GART,HAS3,SEC24C,SHMT2,CPNE7,CD44,PCK2,HSD17B12,SLC25A1,GPHN,FGF2,SMARCAD1,SULT4A1,MARS,PDE2A,PIK3CB,NEU1,TARS,SMPDL3B,HSPA1B,ALG5,SERINC1,DAGLB,GPC2,NDUFAF5,GCSH |
| 1.145e-05 | -11.38 | V$NFMUE1_Q6 | MSigDB lists | V$NFMUE1_Q6 | 229 | 53 | 17758 | 2279 |
PRPF38B,ASH1L,PIGN,ESCO1,PCNT,PRKCSH,CLK1,PAX2,MYNN,RBM19,GBF1,UBR5,GIGYF2,GABPB2,KDM2A,SUV39H2,INTS7,ATP5G2,ZFP37,CHD2,CELF1,KDM5C,ZMYM2,PRPS1,SERBP1,DEAF1,ATF4,PTBP2,STAG1,MIOS,KIAA1143,POLK,COL4A3BP,KIF15,TOP3A,POU2F1,SNAP25,NCDN,EXOC6,DYNC1H1,NSD1,APBB3,HNRNPH3,ZZEF1,LUC7L3,RIOK3,PPP1R12B,NCOR1,WDR33,BMI1,ADK,MID1,LRRC41 |
| 1.160e-05 | -11.36 | cellular amino acid metabolic process | biological process | GO:0006520 | 361 | 76 | 16441 | 2138 |
GGT1,SDSL,RARS2,AARS2,SLC25A21,PLOD1,LPCAT3,SLC6A8,AARS,AHCYL2,PCYOX1L,CAD,FARSA,ASNS,PYCRL,HIBCH,AHCYL1,YARS,MTHFD2L,PPM1K,MPST,TMLHE,NARS2,ATF4,GARS,NARS,HARS,ALDH1L2,MTHFD1L,DLST,ODC1,PYCR1,WARS,GLS,DDAH2,MSRA,PEMT,ATG7,SEPHS2,CARS,DMGDH,SARS,SERINC5,BCKDK,AUH,LARS2,MRI1,HSD17B10,FARS2,PLA2G12A,VARS,PHGDH,YARS2,GART,GATC,ATIC,HARS2,SHMT2,PHYKPL,ALDH18A1,PPA1,MTHFD1,WARS2,PSAT1,PPAT,MARS,MTR,TARS,RARS,EPRS,MTHFD2,SERINC1,DTD1,DPEP1,CNDP2,GCSH |
| 1.174e-05 | -11.35 | BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP | 184 | 45 | 17758 | 2279 |
SRM,NLE1,UBR5,PHLDA2,FAM50A,SUB1,ASAP1,ATIC,PAK1IP1,MED24,GTF3C3,PRMT5,LPCAT1,TRIP13,HN1,SLC38A6,RFC3,NRAS,PTBP2,NARS,GNL3,TSN,GMFB,ADSL,DKC1,CYB5B,RBM28,SAP30BP,EIF3H,PGD,SLC7A1,TAF2,PWP1,TPD52L2,NSF,HNRNPR,COPS5,G6PD,MPV17,GPN1,EIF2S1,KIAA0196,PTP4A2,FNBP1L,KIF1B |
| 1.190e-05 | -11.34 | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | 7269 | 1025 | 17775 | 2278 |
GGT1,CDCP1,DPH1,ACTG1,DCP1B,AARS2,NAT10,MKS1,SBF2,HMOX2,SLC6A8,LPAR3,SKI,ZNF37A,PDZD2,MMP7,ZFHX3,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,NRAS,UPP1,EHMT1,KIF15,ABCC2,SLC7A1,AHNAK,LRRC40,MPV17,RUNX1,VASH2,TMEM63C,FAM189B,TRIO,BTBD9,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,DHX37,APLF,GEMIN4,CCDC88C,SAMD3,ANGPT2,NOM1,RABEPK,ZNF675,ALG6,KCNQ3,ARID5B,IDH3G,SNAP25,TRIM37,SRA1,DYNC1H1,KPNA1,GSTO2,PDLIM1,EHMT2,TRAP1,BPNT1,SRP14,ARHGAP10,NUP43,MCM9,CD96,ESAM,ACD,SETD5,INTS12,MSH4,KIAA1549,LYST,KMT2D,ZNF480,SLCO6A1,PCNXL2,MEF2D,KCNH3,DSP,KDM4B,ASTN2,ARL13B,POLR3E,CENPBD1,CEP170,BAG1,MAPT,RAB30,MORC2,ATG2B,IP6K2,TRIM22,SNW1,CFDP1,UNC13A,ACOT11,LTN1,RAPGEFL1,ZNF710,SAMD4A,RPL22L1,SPTAN1,VPS37A,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,PPIP5K2,UBC,CCDC150,NSD1,SRCAP,HERC1,SORCS2,GPATCH4,CYP24A1,RBM33,TRIM16,FAM13A,NLE1,SCAF8,ECM1,ANKRD11,HKR1,ZMYM2,FAM184A,VPS13B,FMNL3,MIOS,ANK2,LAMA2,KCNH2,KRTCAP2,DLST,BSN,DYRK1B,TCF7L1,INSIG1,CHD3,E2F4,DPP4,ADAM9,PPP3CC,CTU2,FOXO1,CLK1,ARID1B,SPIRE1,CEP290,VPS72,VAPB,LRSAM1,SNX29,IFT43,SETD2,OBSCN,TCF7L2,TBC1D2,TTC38,CASS4,GGT7,USP7,MPI,SART1,OLFM2,PAPD4,ARID2,OSBPL9,NTSR1,LAGE3,RIPK1,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,URB1,PLXNB1,IDI1,JAG1,FGGY,MYH15,KDM3B,SSFA2,TEX19,KIRREL2,VIM,NHSL1,EIF3H,ZNF251,TJAP1,LMBR1L,EIF2B3,PARD3,DMGDH,ESCO1,VARS,RBM19,FOXP1,HIST2H2AB,ANKRD54,ADH5,SURF2,TMEM161A,POLR1B,LRRIQ1,SMARCAD1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,SMPDL3B,CDH24,TAF4,TBX3,BCAS3,USP20,RBM26,RBPJ,NR2F2,KIF1B,LUZP1,PRKCSH,PRKCA,NBEAL1,LPIN1,EXOC1,SUCLG2,CHD2,CSGALNACT2,ZNF646,DENND4A,SON,DDX60,CLNS1A,GNAI1,DOT1L,OSBPL1A,SPOP,DDAH2,TRRAP,SH3RF1,LSM14A,NSMCE1,HIC2,WDR66,RFXAP,SPOCK3,ZMAT3,SPOCK2,PRPF38B,JUP,LARS2,ST6GAL1,DLGAP4,CENPB,MTUS1,TECTA,HR,SCAF1,CNOT4,FDFT1,EXOSC2,RREB1,PRIM2,PCCA,RAPGEF4,ARID1A,TPRA1,SLC26A11,PHF6,ASCC3,MTHFD2,VCAN,SPEN,ZCCHC6,SQLE,NCOR1,SMYD3,CPT1C,SYT17,BIRC6,UROD,TMEM104,PTPRG,PABPC1L,FLNB,IGSF1,DECR1,ASNS,SLX4,ARMC6,PPID,TTC3,CASP8AP2,BRD4,GON4L,PREX1,LRRC8A,GNL1,MEGF11,SETD7,ERC1,HSD3B7,ZBTB25,BAZ1A,DNTTIP1,WDR5B,SMARCC1,G6PD,LARGE,SLC4A7,TBXA2R,SETD6,SSH2,BRAF,B4GALT5,KIF5C,GIGYF2,ABL1,NEBL,DYNC2H1,CELF1,ERRFI1,NAV3,FER1L5,SLC40A1,TTLL5,ZFYVE1,PACS1,BMS1,GUF1,SLC23A2,DDX50,ATM,SVIL,IPO4,ATRX,PCYOX1L,DST,ANAPC11,SLC39A7,MYH3,ZEB1,KIAA0922,HCFC2,CARM1,CEP128,SRPK2,DTNB,TNK2,DEAF1,SESN2,ARRDC3,VWCE,TMEM216,KSR2,MTHFD1L,SGK2,KMT2C,ST3GAL5,YTHDF2,ARPC3,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,EME1,DCAF5,FBXO45,RHOBTB1,ZCCHC8,VTA1,SMG7,EVPL,ELL,PPAT,ELOVL6,ELP3,ZBED4,JMJD1C,ZFP14,LIG4,EIF2A,CORIN,AGAP1,POP1,BICD1,KIAA0355,FSCN1,FAT1,KIAA0754,TMEM117,TBL1X,PDE9A,N4BP2L2,DMXL2,SMARCA4,TBCCD1,PIBF1,SBDS,ZC3H13,SOCS1,PPFIBP1,ITGAX,TMEM120B,C6orf89,AUP1,MAML3,PRAME,GRHL3,METTL2A,ATXN1,EDEM2,UBR4,ARMC4,IKZF4,HNRNPR,ZNF557,CEBPZ,WDR73,ARNTL,RNF130,ARC,SMG1,BCKDK,SUPT6H,ARL15,DYM,PDE4B,ATF7IP,MED18,SEMA3E,SOGA1,ENOX1,MFHAS1,FAM49A,BMP6,PIP4K2A,SEC24C,STC2,DCTN4,LDLRAD3,ERI3,MICAL3,MARCH9,KDM6B,SLC6A16,DNMBP,CRIM1,KDM5A,SCFD2,ZNF324B,PDE2A,NAALADL2,ZNF221,WDR35,AGTPBP1,VPS37B,NFKBIB,GNB3,HLTF,SYNJ1,NUP160,NOS1AP,AMBRA1,NEK6,SREBF2,RABGAP1L,RASSF3,FAAH2,PDS5B,HRG,PTPRM,RFX2,AKAP12,MSRB3,C10orf76,TMSB4X,STOML2,DDX3X,BRCA2,MEF2C,HERC2,NHS,RSF1,SLC1A1,SLC39A11,ABCA7,DDX56,EIF2S2,INTS7,MCM5,NOC3L,PRMT5,MAP3K12,ZNF518B,COQ3,FMNL2,HMGCR,FADS1,COL17A1,RB1CC1,TSPYL4,PRDM16,EPS15L1,RYR2,EVI5,CPT1A,ABCF1,NCDN,ZNF655,VPS13C,LRP1B,LEMD3,ZNF160,SURF1,WDR33,MB21D2,SPRED2,ZNF516,DNM3,ABCA3,BTBD2,NPAS2,ATP6V1A,PDK4,MYH9,NECAP1,AGAP6,TUBB6,STAM,EEA1,PRKD3,ABCA12,ZKSCAN1,ERI1,FMNL1,LSM10,KRT7,FAM111B,TTC28,FKBP3,FGFR1,TAF2,GNG2,PES1,CDC16,IQCH,PAM,ZBTB11,YEATS2,LAMA5,ANKS1A,LRCH1,ZNF786,XPC,TRAK1,AKT1S1,TGFB2,MBNL1,RSRC1,POM121,TADA3,KRI1,SUV39H2,PVRL3,ACAP3,ARHGAP1,HNRNPM,DIS3L2,DDHD1,ERICH1,CLYBL,ARHGAP39,FRA10AC1,PDE3B,CASC1,RPA1,TRIB3,NME1-NME2,PXDN,PLPPR2,PTPN4,SLC25A19,SLCO5A1,GPAM,PSAP,DOCK6,CORO2B,BCAS4,FAM227A,POLR1A,TFIP11,PPARGC1B,MFGE8,SEC16A,BIRC2,GIT2,ARHGAP18,DHX33,PHKA1,UBAP2L,ZNF85,ETV1,CDC37,PTPRK,TMPO,FLNC,METTL1,CHD9,SKIV2L2,ZNF414,BAZ2A,HARS,GDPD1,MED27,ZNF91,KIF16B,PEX1,CCDC28B,TP53BP1,PER1,RAD51B,TNFRSF1A,SGSM2,AOC3,ITPRIP,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,ABCA5,PDE10A,SAMD11,GTF2H1,SYNJ2,ALDH18A1,NT5E,NAA38,CAMKK2,TRAPPC9,TLE3,RNH1,MEX3B,SUPT5H,TRAPPC6B,VAC14,NR2F1,PGD,NAP1L5,ATXN7,FAM135A,ITPRIPL1,SYNCRIP,SNAP23,DNAH17,TBPL1,ZNF430,PPP1R12B,CYLD,ZNF709,PELP1,KDM1A,CAD,UBR1,DNAJB6,ARMC5,C15orf40,ZDHHC6,HIBCH,ZFP37,CORO1A,CTC1,TMEM200A,SEC24A,PCGF3,WDR36,GLTSCR2,NARS,THSD4,MANBAL,AKAP13,ENC1,NUP214,TMEM186,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SIX5,CLEC16A,ZNF333,ITGA2,ZNF436,NFASC,ZNF18,SEPT5,UNC13D,MAP3K13,FAM46B,MAP1S,CSNK1A1,RMI1,ZNF594,SACS,ANXA7,PCK2,FAM71E1,ADAMTSL3,ZMYM5,DHX34,TEX14,PEAR1,RHOT2,TMEM175,PIK3CB,TPD52L2,MSH3,GLG1,EIF2S1,ITGB4,RPS6KC1,MIPOL1,CGN,MYCBP2,PRKAB2,TMEM109,ENAH,IKBIP,UBR5,MGA,GIPR,PAK1IP1,RNF111,ME1,CEP135,MEIS3,TBC1D8,DDN,DPF3,SETD1B,SKIL,HSDL2,VPS13D,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,SYNPO,PTPN14,IFT57,CELSR1,DROSHA,ZHX3,ANKRD17,OPHN1,PID1,GTF2IRD1,TGFBR2,CHD5,PRKCE,PI4KB,ASAP1,COPS3,VWDE,SLC16A9,GTF3C3,IGF2BP1,PRPS1,USE1,SCAF11,ADARB1,DDX28,SIK3,SYNGAP1,AOC2,KIAA0586,PTPN12,TTYH2,PLCB1,LYRM7,ZNF425,DAGLA,EPRS,KIDINS220,NSF,UBAP1,ZZEF1,ZBTB12,PURB,UMPS,PEX13,IQSEC2,RTTN,PTCD2,TBKBP1,TRPM2,AMOTL1,URB2,HFM1,OLA1,KLHL18,SLC25A44,PDE3A,TERF2IP,CHD7,PHC2,TMEM184A,SHC1,VGF,NBEA,KMT2A,PLEKHA4,RFC4,ZCCHC14,MTIF2,WDPCP,DLG4,MED16,TBC1D16,STK10,CPED1,HTR7,VDR,DNAJA3,ZNF236,ALKBH1,ANXA2,MDN1,PDCD11,NCOR2,C10orf2,SLC25A12,MYNN,RTN4,MON2,MLH1,IKBKAP,FOXO3,NEDD4,TMCO6,DCTPP1,NISCH,COPS7B,EXOSC4,NLGN3,PLEKHG4,TSHZ1,WDFY3,WDR18,KCNMA1,FZD3,OASL,FBXO21,KLHL22,HELZ,MYOM2,BRWD3,RABEP1,STK4,LRRC41,SLC43A1,PHF3,MVK,FEM1C,NF1,UBN1,PTPRA,TRPM6,FANCD2,PLOD1,RCHY1,ZNF107,BCOR,SNAPC4,CUTC,SMARCB1,MRPS30,EDC3,SRPRB,ZNF804A,RTN1,LONRF2,THADA,YLPM1,RELB,JOSD1,POLR3B,PCOLCE2,NDUFA6,SLC27A5,TRIM14,ZBTB17,LAMA4,TRIM13,GPM6A,TXLNG,CMIP,SOX4,TCTN1,GEMIN5,TMEM132B,UBTF,DNAJC1,MKL2,RLTPR,ABCC3,GALNT10,ZNF397,RELL2,FN1,TAF1,SEC24D,PAX2,MED13L,XPO7,PHGDH,ETFB,RHBDD1,TOX4,CEP164,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,GLTP,CPSF3L,RANBP6,PDE4A,TBXAS1,WWC1,PSMA1,PRDM1,ANKRD20A4,DNAH14,MYBBP1A,INTS5,SDCCAG8,EXOC4,ZFP90,KIAA1328,ASH1L,PCNT,CELSR3,ST7L,GBF1,VPS18,FARSA,CAMTA2,RPS6KL1,SLC38A2,ZNF142,CPSF3,MET,ZNF460,HTRA2,HN1,MCEE,PHLDB2,FAM172A,SFSWAP,R3HDM1,NLN,ATP8B2,PUSL1,RAB10,RAD54B,TPK1,ZC3H12A,PLIN2,HYAL3,ADNP,SRFBP1,HEATR1,SCARB1,USP11,TSPAN5,ECHDC1,KLHL24,TNIK,SULT1C2,PPHLN1,CLSTN2,MFSD10,SFI1,PRKCH,GART,CTNNBL1,DSG2,SHMT2,CLDND1,DMRT1,PSMC3IP,ANKMY2,PHACTR2,MARS,LENG8,MEN1,TARS,RERE,ZNF708,ALG5,MPP7,MBD6,TATDN1,ZAK,MMP16,HRH1 |
| 1.195e-05 | -11.34 | acute_lymphoblastic_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_leukaemia | 2279 | 357 | 17775 | 2278 |
MYCBP2,GNB3,DPH1,SBF2,PRKCA,NUP160,SYNJ1,UBR5,GIPR,PDZD2,SREBF2,NEK6,PDS5B,SRRM2,FTSJ3,CDK6,SPAG6,NRAS,OSBP2,AP4B1,NFIA,C11orf80,TCEB3,EFHC1,SEMA3F,ABCC2,SON,GZF1,SKIL,DDX3X,TRRAP,ARL6IP5,HIC2,DNAH2,RIOK1,RUNX1,WDR66,MEF2C,HERC2,EP400,LARS2,PRPF31,SIRT7,TRIO,PIK3R4,PID1,SSR4,TGFBR2,ABCA7,PRKCE,CNST,TSPAN2,KIAA1671,APLF,USPL1,MCM5,CACNB2,ZNF326,MED24,PRMT5,CNOT4,MAP3K12,HMGCR,ADARB1,SCAF11,SIK3,IFRD1,RAPGEF4,ZNF512B,IMPDH2,ARID1A,ZNF655,ARIH2,PHF6,DYNC1H1,EPRS,LRP1B,EHMT2,SPEN,ZZEF1,RIOK3,DPEP1,MAP2K4,RTTN,RAB11FIP4,TRPM2,BIRC6,BTBD2,HFM1,PDK4,DDR2,TMEM104,PTPRG,FLNB,RPP30,PRKD3,SLX4,ASNS,TMEM184A,KDM2A,FMNL1,KMT2A,DENND1A,CDK12,PMS1,KMT2D,BRD4,PDK1,FAM111B,ADAM32,ATP6V0A1,KCNH3,TBC1D16,STK10,VPS53,MAT2A,FGFR1,VDR,PES1,TAF2,CAMK2D,SMARCC1,HIPK2,ZNF236,WDR7,RPS6KB1,TRAF3,MDN1,YEATS2,NCOR2,BRAF,XPC,TCF3,ZNF280C,FARS2,MLH1,RNASEH2B,MBNL1,KRI1,ABL1,PTRF,NISCH,SDCBP2,COPS7B,ZNF710,SOX6,MS4A15,SPTAN1,CLK2,FAM120B,TMC7,PFKFB4,TTPAL,TSHZ1,CASC1,DDX49,OXSR1,TRIB3,SRCAP,BAZ2B,IREB2,HELZ,ATM,APAF1,ADK,DOCK6,CORO2B,IPO4,STK4,CUL7,LETM1,ATRX,NF1,KIF5A,TFIP11,MFGE8,HECTD3,TRPM6,CSNK2A1,PLOD1,RNF43,BCOR,STK33,GIT2,MAP2K3,SMARCB1,ABL2,SRSF2,DHX33,ANKRD11,SLC35C2,PRKACB,SRPK2,PTPRK,SF3A1,CDC37,DSC3,DBN1,TNK2,DEAF1,TRIM13,SLC3A2,MIOS,ABCC4,ANK2,CDK4,ARRDC3,TFPI,GMFB,COL4A3BP,KSR2,MARCKSL1,BRCA1,MTHFD1L,LAMA2,SGK2,KMT2C,SOX4,ZSCAN2,YTHDF2,DYRK1B,MSRA,TMCO1,TP53BP1,CHD3,MKL2,CSMD3,MAGI1,COPS6,USP15,VIPR1,CLK1,TAF1,UBXN1,ALG8,SMG7,KIAA1958,ZNF358,MCAM,PDE10A,CTR9,SYNJ2,LRP3,POLR1E,N4BP2,CPSF3L,CAMKK2,LAMC1,USP49,ZBED4,OBSCN,WWC1,SUPT5H,SYT1,ACOXL,TCF7L2,PGD,PRPF40B,SYNCRIP,KIAA0355,FAT1,INTS5,TMEM117,TBCK,ZBTB24,TCF12,USP7,CHMP2A,PCNT,CELSR3,SLC5A5,MYO7A,COBLL1,RIPK1,RSL1D1,TMEM177,RNF24,LPCAT3,PLXNB1,KDM1A,RIOK2,ZC3H13,VPS18,FARSA,CCDC50,FSIP2,RPS6KL1,PPFIBP1,IKBKB,ZNF142,HIRIP3,RNF2,MYH15,FHIT,CORO1A,ADCK4,MET,VCL,CTC1,NARS2,EVL,COL5A2,PARP2,SFSWAP,NUP214,UBR4,ALAD,DUS3L,ADNP,TIMM17A,ATG7,SCARB1,SMG1,TMCC1,BCKDK,TNIK,MAP3K13,SUPT6H,RFX1,CAMK1,KLC4,PDE4B,ARFIP2,MAP1S,APRT,CSNK1A1,POGZ,GFM2,MAN1A1,PRKCH,DSG2,CPNE7,PKNOX1,RPS6KB2,KDM6B,DNMBP,ADAMTSL3,MON1A,KDM5A,SMARCAD1,TOP3A,TEX14,ARHGEF12,YIPF3,ARHGAP32,GPNMB,RHOT2,MKX,CDH24,DSC2,GPC2,AGTPBP1,USP20,RPS6KC1,XPO6,KIF1B,ZAK |
| 1.200e-05 | -11.33 | purine nucleotide catabolic process | biological process | GO:0006195 | 43 | 17 | 16441 | 2138 |
PDE4A,ITPA,PDE4B,PDE2A,NUDT15,PDE3B,PDE3A,PDE8B,CAT,AMPD3,HPRT1,PDE10A,NT5C,PDE9A,MUTYH,OGG1,NT5E |
| 1.212e-05 | -11.32 | CAIRO_HEPATOBLASTOMA_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_UP | 201 | 48 | 17758 | 2279 |
HMGA2,RHOBTB1,VPS45,SMARCA4,RNF43,IGF2BP2,IKBKAP,PRKCA,DENR,C6orf48,MCAM,SREBF2,NUP133,UBAP2L,MRPS27,GREB1,GSTA4,PEG10,ETV1,HMGCR,FDFT1,KDM3B,PMS1,LAMC1,KDM5B,CRIM1,TSPYL4,CDK4,TSN,R3HDM1,CAMSAP2,IMPDH2,SOX4,PALLD,MTR,RPA1,DKK1,UBAP2,EHMT2,SMARCC1,ARL4A,TBX3,FDPS,SQLE,HEATR1,RPS6KC1,FNBP1L,SMYD3 |
| 1.251e-05 | -11.29 | LTE2_UP.V1_DN | MSigDB lists | LTE2_UP.V1_DN | 190 | 46 | 17758 | 2279 |
NCOR2,ID1,UTP14A,C16orf45,ZNF107,CSTA,NUP160,SLC1A1,IGSF1,CHN1,RRN3,GART,JAG1,SLC7A11,PMAIP1,IFIT5,STC2,LTN1,GREB1,PEG10,NRIP1,ZMYM2,TRIM14,PTPRK,PCSK6,IFRD1,PTBP2,PSAT1,MYO10,PSPC1,JMJD1C,LGALS1,SATB2,CAV1,OASL,PLCB1,DDX60,ISG15,GADD45A,KLF4,SVIL,SLC16A1,ARHGAP12,TAF12,NRP1,N4BP2L2 |
| 1.259e-05 | -11.28 | LIU_SOX4_TARGETS_DN | MSigDB lists | LIU_SOX4_TARGETS_DN | 294 | 64 | 17758 | 2279 |
MVK,PAFAH1B1,PPP2R2A,PBX1,SMARCA4,LPCAT3,CHAC1,SPATS2,FAM13A,DECR1,PPFIBP1,PNPLA4,FUT11,LONP1,RFC3,RBCK1,PDK1,TFPI,PSMG1,CAMSAP2,C10orf76,MTHFD1L,POLG2,ARPC3,TMCO1,SLC25A11,NOLC1,AP2S1,MAPT,CARS,YDJC,EP400,AK2,TRAK1,KIF5C,WDR26,OPA1,NDUFS7,PRKCH,GART,PPIL2,PMPCA,SELT,ERI3,MICAL3,SERBP1,RPS6KB2,PPP1R9B,PPAT,ZNF654,PSMC3IP,LDHA,ZNF512B,USP10,SMARCD3,MEN1,CYB5B,CPT1A,ARIH2,ATP9B,INF2,EPRS,PDLIM5,SMYD3 |
| 1.271e-05 | -11.27 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 722 | 132 | 17758 | 2279 |
NF1,GPBP1L1,SLC29A1,PRR4,FAM13A,UBR5,AHCYL2,RAP1A,ZFHX3,MARVELD2,XRCC2,HKR1,CHD2,SRRM2,ZMYM2,LAMA4,FMNL3,CHD9,TRIM13,EIF4E3,NFIA,TCTN1,TAF9B,UBTF,TOM1L2,LSM14A,SH3RF1,MKL2,CTAGE5,BBIP1,CLU,GALNT10,MAGI1,EPM2AIP1,FOXO1,MED13L,SMG7,PID1,RSF1,XPO7,TGFBR2,SLC1A1,ARID1B,NAMPT,TOX4,RNF141,KIAA1671,PI4KB,VAPB,SAMD13,SYNJ2,ZCCHC7,FDFT1,MSI2,GTF2H3,SIK3,TRA2A,ZNF512B,WWC1,CAT,IRS1,VPS13C,SERF2,SNAP23,ZNF160,WDR33,MACROD1,PDLIM5,NDUFA5,CYLD,MMRN2,ARID2,PPP2R2A,SSBP2,PTPRG,FLNB,TMEM150C,CBR4,WAC,CYB5D1,SOBP,KDM3B,GON4L,SSFA2,KRT7,GLTSCR2,WDPCP,ATXN1,NLN,VIM,ALAD,KDM4B,HIPK2,WDR7,FKBP5,ANKS1A,TSPAN5,KLHL24,RFX1,DYM,MRI1,TRAK1,ATF7IP,FOXP1,RPS6KA5,POGZ,MBNL1,PEX7,PRICKLE2,ARHGAP1,CD44,SOX6,TSHZ1,SLC40A1,IL11RA,AP4S1,ERICH1,PPP1R21,FZD3,ASAP3,PHACTR2,RSBN1,KLF6,RERE,FBXO21,NSD1,ACOX1,HERC1,CSRNP1,NR2F2,ZAK,STK4 |
| 1.274e-05 | -11.27 | GTPBP4 (GTP binding protein 4) | protein interactions | 23560 | 82 | 27 | 16036 | 2270 |
WDR36,NIFK,IFRD1,CUL7,FN1,DDX24,UTP14A,DDX18,GLTSCR2,SIRT7,DKC1,NOP58,PUM3,NOP56,PES1,PWP1,POP1,DDX56,MPHOSPH10,COPS5,CEBPZ,RNF2,MED20,POLR1C,FBL,ZC3H3,NMD3 |
| 1.303e-05 | -11.25 | NUCLEOLUS | MSigDB lists | NUCLEOLUS | 120 | 33 | 17758 | 2279 |
ZNF346,IKBKAP,NOL3,NOP56,RPP30,ABL1,DDX56,MPHOSPH10,GEMIN4,PNMA1,POLR1E,TOP1,NOM1,DDX24,GNL3,POLA1,ELP3,NOL8,NOL6,APTX,DKC1,OASL,NOP58,POLR2A,UBTF,POP1,MYBBP1A,CCNT1,ZNF330,SRP68,RBPJ,POLR1C,NOLC1 |
| 1.312e-05 | -11.24 | macromolecule modification | biological process | GO:0043412 | 3008 | 463 | 16441 | 2138 |
PTP4A1,MYCBP2,ASCC1,CUL4A,DPH1,PRKCSH,PRKAB2,AARS2,HLTF,PRKCA,NUP160,AARS,UBR5,NEK6,RNF111,DPH6,FNIP2,KDM5C,TRMT10A,FXN,FUT11,FTSJ3,CDK6,PPM1K,SEH1L,NRAS,SETD1B,RNMT,KLHL23,PTPRM,EHMT1,EYA3,TCEB3,DCUN1D5,ZDHHC14,SPOP,DOT1L,BRCA2,TRRAP,SSU72,RAD18,CCNT1,SH3RF1,NSMCE1,RIOK1,CCNB1IP1,BMI1,BLMH,SPOCK2,SPOCK3,PTPN14,MEF2C,HERC2,WDR75,EP400,SLK,ST6GAL1,TRIO,SIRT7,PIK3R4,DPM3,TGFBR2,PARN,CDC73,CHD5,ABCA7,FKBP1A,PRKCE,UBE3A,ENTPD5,USPL1,COPS3,MYC,ALKBH8,PIGG,MED24,PRMT5,CNOT4,MAP3K12,ADARB1,PEA15,GATAD2B,SIK3,GTF2H3,SYNGAP1,ALG6,ANAPC13,WDR61,STAG1,RB1CC1,TYW1,PTPN12,USP10,ATAT1,ST6GALNAC3,TRIM37,USP46,ARIH2,IRS1,SEC31A,ASCC3,EPRS,ALKBH3,EHMT2,NSF,CDK9,RIOK3,SENP3,MACROD1,SMYD3,C18orf25,MAP2K4,MAP2K5,BIRC6,PDK4,DDR2,KLHL18,NUP43,PTPRG,ST3GAL6,UBL5,RING1,NOP56,PHC2,PRKD3,PUS3,SHC1,KDM2A,PPID,UCHL5,WAC,SOCS6,TTC3,PXK,KMT2A,TRMT12,CDK12,KMT2D,BRD4,PDK1,STAMBP,PCMT1,DLG4,MARCH6,KCNH3,SETD7,DSP,STK10,ERC1,SERP1,FKBP3,FGFR1,FBXL5,CAMK2D,CDC16,NSMCE2,HIPK2,CAMKMT,LARGE,FTSJ1,ACP1,ALKBH1,TRMT2A,RPS6KB1,TRAF3,BRCC3,XRCC4,SETD6,YEATS2,METTL2B,TRIM36,HMGA2,SSH2,BRAF,XPC,B4GALT5,TCF3,TRAK1,JMJD6,GAS6,LIAS,TRIM22,IKBKAP,TGFB2,RPS6KA5,RSRC1,PSMF1,NEDD4,POM121,TTLL11,TADA3,ABL1,NPRL2,SUV39H2,LTN1,COPS7B,EXOSC4,MAP3K14,FBXL19,LYPLA2,SPTAN1,CLK2,FGF9,PXN,TTLL5,APEX1,USP42,TBRG4,PTK2,UBE2K,NOP58,UBC,ANXA1,RPA1,OXSR1,TRIB3,KLHL22,FBXO21,SRCAP,NSD1,ZDHHC11,HERC1,SRD5A3,RNF138,ATM,PTPN4,BMP4,PGAM5,MTMR1,ANAPC4,KDM4C,LRRC41,KAT6A,STK4,PIGM,CUL7,FEM1C,TRIM16,ATRX,NF1,KMT2E,PTPRA,HECTD3,TRPM6,RCHY1,CSNK2A1,PLOD1,RNF43,PPIL1,BCOR,SIRT2,STK33,SEC16A,BIRC2,MAP2K3,ABL2,ANAPC1,COPS4,PHKA1,CNIH3,KANSL1,ATG3,TRMU,ANAPC11,ANAPC10,TRIML2,IPP,POLE3,SLC35C2,GALNT18,OGG1,PRKACB,CARM1,TIMM50,SRPK2,PTPRK,METTL1,TNK2,TRIM13,RBCK1,GCNT2,SIRT6,BAZ2A,CDK4,MED27,GMFB,COL4A3BP,ATG12,KSR2,SUMO3,HDAC8,BRCA1,CAV1,SGK2,KMT2C,KCNH2,ST3GAL5,PAF1,DYRK1B,MSRA,UBE3D,HLCS,TRMT5,PER1,SOCS4,CTAGE5,PPP3CC,ASB3,GALNT10,COPS6,DCAF5,USP15,FBXO45,CTU2,TTN,PIGN,FN1,FOXO1,CLK1,SEC24D,TAF1,MAPK8IP3,LAMTOR3,SMAD7,ALG8,EVPL,RHBDD1,RNF40,RNF141,P3H1,TRMT13,ISPD,PPIL2,GTF2H1,CTR9,SYNJ2,LRSAM1,TRAPPC9,CAMKK2,USP49,ELP3,SETD2,OBSCN,PSMA1,MEX3B,EIF2A,TRAPPC6B,TMEM241,ISG15,UBE2E1,MGAT2,ATXN7,SPAG9,IRAK2,CDKAL1,CASS4,HMBS,TBL1X,PTP4A2,TBCK,BRSK2,NAPA,RNF114,USP7,MPI,ASH1L,CYLD,LAGE3,PIGH,PPP2R2A,RIPK1,RNF24,ARSJ,PIBF1,CSTA,KDM1A,RIOK2,METTL16,CAD,KCTD11,SOCS1,DUS4L,LYPLAL1,GRIN2C,UBR1,NUP133,RPS6KL1,IKBKB,ZDHHC6,ETF1,RNF2,ADCK4,MET,PRMT3,PRPF19,SEC24A,KAT8,PARP2,METTL2A,METTL15,AKAP13,EDEM2,ENC1,DKC1,NUP214,UBR4,PUSL1,USP36,RANBP2,DUS3L,COPS5,ATG7,DUSP19,FKBP5,PUS1,MED20,RNF130,USP11,PPIL3,MUTYH,SMG1,KLHL24,BCKDK,TNIK,ESCO1,MINK1,SH2D3A,MAP3K13,CAMK1,ATF7IP,CSNK1A1,MAN1A1,PTPN2,PRKCH,ADH5,CWC27,SEC24C,HIST2H3D,FBXO31,FBL,RPS6KB2,MARCH9,KDM6B,KDM5B,GPHN,FGF2,SMARCAD1,TEX14,SCMH1,HIST1H4J,MEN1,PEAK1,NEU1,ALG5,AGTPBP1,ADAT2,CUL2,EIF2S1,FNTB,USP20,TAF12,RPS6KC1,ZAK |
| 1.333e-05 | -11.23 | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | 265 | 59 | 17758 | 2279 |
CDCP1,MCM6,FN1,DROSHA,ACTG1,DBF4,ALG8,PPP2R2A,MYH9,CSNK2A1,SMARCA4,IGF2BP2,PLEK2,TTI1,CUTC,MBNL1,FLNB,PHC2,CAD,IDI1,UCHL5,TIMELESS,ANXA5,POLE3,PRMT5,VCL,SAMD4A,PRPS1,TRIP13,MTHFD1,TMPO,NT5E,PMS1,RFC3,PARP2,POLA1,ELOVL6,UPP1,BCS1L,LDHA,RAP1GDS1,CAMSAP2,PALLD,MCM2,UBE2K,EIF5B,ODC1,NUDT15,MAK16,CHAF1A,FGFBP1,RNF138,SQLE,PRPF4,HMBS,NOLC1,XPO6,GCSH,GALE |
| 1.354e-05 | -11.21 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | 835 | 149 | 17758 | 2279 |
SLC37A3,MYCBP2,LUZP1,PRKCSH,MRPL10,NAT10,PLOD1,FAM13A,UBR5,EDC3,NEK6,SREBF2,PHF5A,LYRM5,PPM1K,MPST,LAMA4,ACADS,RBCK1,TXLNG,ABCC4,CMIP,BAZ2A,PPARG,C2orf76,HSPA5,TMEM216,ATG12,DLST,MGST1,MSRA,EIF4ENIF1,HSDL2,TOM1L2,HIC2,SYNPO,SEC24D,ITPRIP,C11orf54,PITPNM1,ETFB,MTUS1,SCAF1,ZNF326,TNPO3,MAP3K12,COQ3,CAV2,IFRD1,LAMC1,STAG1,PCCA,ARID5B,TBXAS1,TTYH2,ATAT1,PLCB1,CPT1A,ANGPTL4,NR2F1,ZNF655,TCF7L2,EXOC6,EHMT2,RIOK3,CCDC85B,PTP4A2,SMYD3,NDUFA5,PPDPF,SUCLG1,MMRN2,SLC48A1,KIAA0232,CD99L2,PPP2R2A,UBL5,FDX1,FLAD1,SPG21,CCDC50,SHC1,SETD5,HIBCH,MSH4,CMPK1,LSM10,GARS,FAM172A,GON4L,R3HDM1,DLG4,RANBP2,ALAD,HOXA3,DUSP19,H2AFX,ECHDC1,TMEM33,MINK1,CAMK1,TRAK1,LETMD1,PPHLN1,AKT1S1,ENOX1,INPP1,GIGYF2,MBNL1,REEP5,CTNNBL1,ANXA7,PTRF,SEC24C,TANK,LDLRAD3,FBXO31,SAMD4A,HSD17B12,KDM6B,PPP1R9B,LSM12,FGF2,PSPC1,KDM5A,WDR18,MARS,TMEM175,UBC,ECH1,ANXA1,MRPL36,MKX,ZRANB3,OXSR1,ETFDH,GADD45A,MPP7,ACOX1,ADAT2,ORC5,ZNF32,MBD6,NR2F2,RABEP1,DDIT3,GCSH,NIT1,LRRC41 |
| 1.362e-05 | -11.20 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | 185 | 45 | 17758 | 2279 |
COMMD10,WDR74,PLRG1,NAT10,NFX1,SLC29A1,TIMM10,BZW2,URB1,NUBPL,BRE,PUS3,MPHOSPH10,SOCS1,ATIC,TRIAP1,IPP,CTR9,C16orf58,POLE3,GEMIN4,ERRFI1,PRPS1,SLC25A1,EXOSC2,PPAT,PARP2,HAUS6,ABCF2,BRCA1,GSTCD,DKC1,POLR3G,ATAD5,MTHFD2,KPNA1,SYNCRIP,COPS5,POLR3E,UMPS,SCARB1,EME1,TMEM101,BRCC3,PRKAR2A |
| 1.387e-05 | -11.19 | AACTGGA,MIR-145 | MSigDB lists | AACTGGA,MIR-145 | 219 | 51 | 17758 | 2279 |
ARHGAP26,SNX27,SSH2,ADAM19,SCAMP3,PAPD4,FOXO1,ACTG1,ACTR3,SBF2,SPATS2,NBEAL1,TGFBR2,CLINT1,SEMA6A,FLNB,BLOC1S2,ATXN2,FSIP2,LARP4B,FXN,CDK6,ANGPT2,VPS13B,PHLDB2,PXN,RREB1,GPHN,BAZ2A,EYA3,EIF4A2,SETD2,AKAP12,LENG8,FKBP3,USP46,BSN,SPOP,YTHDF2,SMAD3,IRS1,FAM135A,KIAA0355,H2AFX,TBPL1,HIC2,CSMD3,PTP4A2,GGT7,KIF1B,LMBRD2 |
| 1.391e-05 | -11.18 | DNA_BINDING | MSigDB lists | DNA_BINDING | 587 | 111 | 17758 | 2279 |
TRERF1,UBN1,NPAS2,SMARCA4,HLTF,FOSL2,SNAPC4,GABPB2,TERF2IP,ZFHX3,PHF5A,PDS5B,ZNF142,RELB,ZEB1,CHD2,ZNF85,MSH4,ETV1,OGG1,MAML3,ZBTB17,PMS1,RFC3,ZNF124,ATF4,TFCP2,NR6A1,PPARG,RFX2,KIF15,POU2F1,WDHD1,BRCA1,SOX4,MCM2,SON,ZNF197,RAD54B,BATF3,ZBTB25,SMAD3,EXO1,SUPT4H1,IKZF4,ELP2,CHD3,CCNT1,E2F4,CEBPZ,PQBP1,RAD51B,DLX2,RUNX1,XRCC4,HMGA2,EGR1,FOXO1,ZHX3,SUPT6H,XPC,RFX1,KHDRBS1,PAX2,TCF3,NFX1,MAP1S,HES6,MYNN,RCAN1,MLH1,TRIM22,IKBKAP,RLF,FOXO3,ARID1B,ZNF239,TADA3,SUB1,MBD2,MYC,BUD31,DMRT1,SNAPC5,TERF2,TOP1,APEX1,KDM5B,POLA1,KDM5A,ARID5B,ELP3,LIG4,SCMH1,PRDM1,APTX,ARID1A,OASL,FOXC1,NR2F1,RPA1,ZNF155,ALKBH3,HIF1A,CDK9,TBX3,ORC5,MSH3,PURB,ZRANB2,RBPJ |
| 1.446e-05 | -11.14 | GSE17721_CTRL_VS_LPS_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_4H_BMDM_UP | 191 | 46 | 17758 | 2279 |
NCOR2,HM13,SEC24D,RARS2,RTN4,SSBP2,SEC16A,LCLAT1,PAG1,FAM50A,SPG21,DTNBP1,CTR9,ANP32B,TMEM14C,ELOF1,RPS6KB2,CRADD,SMARCAD1,ELOVL6,RNH1,IL6R,SYT1,EVI5,CPT1A,TMEM175,NEU1,VAC14,BSN,MRPL36,MGAT2,KLHL22,HELZ,ELP2,ADNP,NSF,SRRD,ORC5,H2AFX,CRCP,NDUFS5,HMBS,PTP4A2,BRCC3,SYNPO,SGSM3 |
| 1.458e-05 | -11.14 | PROTEIN_COMPLEX | MSigDB lists | PROTEIN_COMPLEX | 803 | 144 | 17758 | 2279 |
EIF3C,KIF5A,PPARGC1B,CACNA1H,NUP160,SNAPC4,SMARCB1,ATP5G2,ATG3,JAZF1,ANAPC11,ZNF148,NDUFA6,CDK6,PRKACB,TIMM50,NR6A1,CDK4,KIF15,SUMO3,HDAC8,BRCA1,KCNH2,KRTCAP2,CHAF1A,ARPC3,GNAI1,BRCA2,TRRAP,TNNC1,DCTN3,TRIP6,TAF1,HES6,DPM3,RSF1,XPO7,TGFBR2,KCNJ14,TIMM10,ARID1B,NDUFS7,ABCA7,SUB1,EIF2S2,CNST,INTS7,CEP290,CACNB2,GTF2H1,GTF3C3,AGL,CPSF3L,SCAF11,TIMM8B,LAMC1,KCNQ3,POLA1,EIF4A2,ELP3,BCS1L,RNH1,LIG4,ARID1A,EIF2A,MYBBP1A,KPNA1,HIF1A,INTS5,CDK9,PURB,COG5,PAFAH1B1,NPAS2,ATP6V1A,ACTR3,VTI1A,MYH9,PPP2R2A,SPATS2L,BRE,ACD,NUP133,SNTG2,INTS12,ITGAX,VCL,SAP30,RFC4,RFC3,EIF3J,ATXN1,MED16,NUP214,ERC1,EIF3H,ATP5D,TAF2,SMAD3,CAMK2D,RANBP2,ELP2,SMARCC1,KPNA3,COPS5,TIMM17A,ARNTL,ITGA2,INTS9,EIF2B3,BRCC3,XRCC4,MID1,AP2S1,MAPT,BCKDK,MAP3K13,KIF5C,MED18,IKBKAP,MRPS11,NDUFV1,PPP1R9B,PXN,KDM5A,ABCF2,KCNMA1,CCDC113,RANGAP1,IL6R,MEN1,POLR2A,RPA1,POLR3G,CACNB1,TAF4,MSH3,EIF2S1,TAF12,POLR1C,ITGB4,KIF1B,ANAPC4,GCSH |
| 1.464e-05 | -11.13 | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | 417 | 84 | 17758 | 2279 |
RTTN,MPI,TBKBP1,TRIM16,C16orf45,DDR2,PBX1,CD99L2,ADAMTS6,FAM122B,FAM13A,FRRS1,RIOK2,FLAD1,ZNF608,PUS3,ARHGAP18,HYAL1,CORO1A,ETV1,MPST,ZNF646,MOSPD1,SRPK2,GPM6A,LIMA1,ANK2,NOL8,DLG4,METTL15,TOR1AIP2,SAP30BP,LSG1,MGST1,CCDC28B,PYCR1,PLIN2,GNG2,MKL2,FTSJ1,INTS9,DUSP19,RAD51B,FIS1,CCDC53,FAM189B,PRPF31,CAMK1,KLC4,TRAK1,PDE4B,NSUN6,C14orf159,ATXN7L1,ZNF239,SLC7A11,ALKBH8,MED24,SYNJ2,CD44,CWF19L2,ANGPT2,C12orf4,NAV3,KDM6B,USP49,AGPAT4,ZC4H2,C11orf49,MBNL2,EHBP1,SYT1,ECH1,RDH11,ZRANB3,NME7,EXOC4,BIVM,DNAJC12,IFITM2,IGBP1,NUDT22,GALE,CPT1C |
| 1.479e-05 | -11.12 | DDX5 (DEAD (Asp-Glu-Ala-Asp) box helicase 5) | protein interactions | 1655 | 195 | 50 | 16036 | 2270 |
DNAJC2,SART1,CUL7,CUL4A,FN1,DROSHA,DDX18,RBFOX2,KHDRBS1,NFX1,SMARCA4,PRKCA,MBNL1,PABPC4,SBDS,IGF2BP3,ABL1,SNW1,RPS16,SHC1,ATXN2,RNF2,FBL,SRRM2,LRSAM1,IPO11,HNRNPM,PRPF19,RPS6KB2,SF3A1,FBXW4,SKIV2L2,SMARCAD1,EIF2A,SGK2,POLR2A,RPA1,SMAD3,EPRS,SYNCRIP,HNRNPR,CHD3,CDK9,HNRNPH3,COPS5,CUL2,FUS,COPS6,XRCC4,SRP14 |
| 1.493e-05 | -11.11 | transferase activity | molecular function | GO:0016740 | 2220 | 355 | 16491 | 2164 |
GGT1,POLB,CUL4A,PRKAB2,NAT10,HLTF,GYG1,CHAC1,NT5C3A,PRKCA,UBR5,CIAPIN1,NEK6,RNF111,TRMT10A,FUT11,ZNRD1,CDK6,FTSJ3,CSGALNACT2,GDAP1,SETD1B,KLHL23,RNMT,UPP1,ALDH1L2,EHMT1,TCEB3,ZDHHC14,DOT1L,TRRAP,BRCA2,RAD18,NSMCE1,RIOK1,CCNB1IP1,NRP1,HERC2,SLK,ST6GAL1,AK6,TRIO,PIK3R4,DPM3,TGFBR2,PRKCE,UBE3A,PI4KB,ATIC,ALKBH8,PIGG,MED24,PRMT5,MAP3K12,CNOT4,LPCAT1,AGL,COQ3,PRPS1,FDFT1,GTF2H3,SIK3,ALG6,PRIM2,POLA1,ATAT1,ST6GALNAC3,CPT1A,TRIM37,MTR,ARIH2,GSTO2,NME7,EHMT2,CDK9,RIOK3,ZCCHC6,UMPS,SMYD3,C18orf25,MAP2K4,HS2ST1,CPT1C,MAP2K5,BIRC6,SUGCT,PDK4,DDR2,KLHL18,ST3GAL6,LCLAT1,FLAD1,PRKD3,SHC1,GSTA4,TTC3,CMPK1,PXK,KMT2A,TRMT12,CDK12,KMT2D,PDK1,PI4KAP2,PCMT1,DLG4,GALK2,MARCH6,KCNH3,SETD7,POLG2,STK10,FGFR1,MAT2A,TAMM41,FBXL5,BAZ1A,CAMK2D,METTL6,NSMCE2,HIPK2,PEMT,CAMKMT,POLR3E,FTSJ1,LARGE,TRMT2A,RPS6KB1,TRAF3,SETD6,METTL2B,TRIM36,HMGA2,BRAF,B4GALT5,IP6K2,LIAS,TGFB2,RPS6KA5,NEDD4,TADA3,ABL1,POLR3D,NPRL2,FTCDNL1,SUV39H2,LTN1,PHYKPL,MAP3K14,FBXL19,CLK2,PFKFB4,PSAT1,CLYBL,WDFY3,POLK,AGPAT4,TBRG4,PTK2,OASL,PPIP5K2,UBE2K,POLR2A,OXSR1,KLHL22,TRIB3,SRCAP,FBXO21,NSD1,ZDHHC11,POLE2,HERC1,ATM,GPAM,ADK,ANAPC4,STK4,KAT6A,SRM,PIGM,MVK,KMT2E,POLR1A,TRPM6,CERS5,HECTD3,RCHY1,CSNK2A1,RNF43,SIRT2,BCOR,STK33,COX10,BIRC2,MAP2K3,ABL2,KANSL1,PHKA1,ATG3,TRMU,ANAPC11,METTL8,HYAL1,IPP,B3GNTL1,POLE3,POLR3B,GALNT18,CARM1,MPST,PRKACB,SRPK2,METTL1,TNK2,TRIM13,GCNT2,RBCK1,SIRT6,CDK4,MED27,COL4A3BP,SUMO3,KSR2,ATG12,BRCA1,SGK2,KMT2C,KCNH2,DLST,ST3GAL5,MGST1,DYRK1B,HPRT1,TRMT5,CRCP,GALNT10,SEPHS2,CTU2,XYLB,TTN,AK2,PIGN,CHST11,TAF1,CLK1,GPAT3,ALG8,NAMPT,RNF141,RNF40,TRMT13,PPIL2,ISPD,GTF2H1,ALDH18A1,PNPLA3,LRSAM1,POLR1E,N4BP2,CAMKK2,PPAT,ELOVL6,ELP3,SETD2,WBSCR22,OBSCN,PRDM1,METTL22,UBE2E1,MGAT2,MYBBP1A,FDPS,IRAK2,HK2,CASS4,CDKAL1,TRMT10B,HMBS,GGT7,TBCK,BRSK2,PDSS2,ASH1L,PAPD4,LPCAT2,PIGH,RIPK1,RNF24,LPCAT3,RIOK2,METTL16,CAD,UBR1,RPS6KL1,FGGY,ZDHHC6,IKBKB,RNF2,ADCK4,MET,PRMT3,PRPF19,KAT8,PARP2,METTL2A,METTL15,AKAP13,DKC1,UBR4,TPK1,HSPB8,RNF130,MED20,EIF2B3,SMG1,KLHL24,BCKDK,TNIK,MINK1,ESCO1,SULT1C2,MAP3K13,CAMK1,NSUN6,TKFC,APRT,CSNK1A1,PIP4K2A,PRKCH,GART,HAS3,KDELC1,SHMT2,POLR1B,FBL,RPS6KB2,GPHN,CRIM1,TEX14,METTL23,SULT4A1,MEN1,PEAK1,PIK3CB,POLR3A,POLR3G,ALG5,CUL2,FNTB,NDUFAF5,TAF12,POLR1C,RPS6KC1,ZAK,GCSH |
| 1.496e-05 | -11.11 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 1762 | 309 | 16036 | 2270 |
PTP4A1,ASCC1,TNFRSF21,ENAH,HLTF,IKBIP,PRKCA,PABPC4,S100A10,ZFHX3,PMAIP1,ZNF148,SRRM2,CDK6,SEH1L,SLC38A6,EIF4E3,NRAS,OSBP2,NFIA,CAMSAP2,ZDHHC14,MAK16,SLC50A1,SLC9A5,STOML2,DDX3X,SLC7A1,LSM14A,RIOK1,RUNX1,TPM1,BMI1,ZMAT3,ZNF532,LPP,SIRT7,MFSD13A,PDCD7,CLINT1,SLC39A11,IGF2BP3,SH2B3,FAM192A,RSPRY1,FKBP1A,PRKCE,NAV1,ASAP1,MYC,TNPO3,ANP32B,MAP3K12,CNOT4,LPCAT1,PABPC1,SERBP1,TERF2,BDNF,SIK3,IFNGR2,PRIM2,ARID5B,TYW1,RDH10,ARID1A,EVI5,MBNL2,TRIM37,MTR,MTHFD2,KPNA1,CDK9,RIOK3,BIVM,PURB,CNOT6,IQSEC2,WDR33,C18orf25,VMA21,SPRED2,TRERF1,CCDC58,DDX18,ATP6V1A,DDR2,SLC25A44,LCLAT1,PAIP2,KDM2A,GLYR1,MRPS27,RMDN3,CMPK1,SERPINH1,CDK12,ZCCHC14,BRD4,LRRC75A-AS1,DLG4,LRRC8A,SATB2,MARCH6,MAT2A,DCBLD2,TAF2,SLC39A14,BAZ1A,YIPF2,SMARCC1,CAMKMT,H2AFX,RPS6KB1,MID1,SSH2,SHQ1,B4GALT5,TCF3,MYNN,BHLHE40,OPA1,FOXO3,GIGYF2,PTRF,RDX,COPS7B,UPF2,CELF1,ERRFI1,YBX3,LARP4B,TTPAL,MRPS10,NXN,RSBN1,R3HDM2,PTK2,CAAP1,FOXC1,POLR2A,RPA1,OXSR1,FBXO21,BAZ2B,HELZ,RNF138,ATM,APAF1,STK4,KAT6A,PIGM,ZNF76,CUL7,FEM1C,RBM33,GPBP1L1,KMT2E,FANCD2,CSNK2A1,NREP,SLC30A7,SRPRB,RAP1A,DHX33,MARVELD2,ZNHIT6,UBAP2L,JOSD1,RAN,SLC25A23,ZMYM2,CARM1,AEBP2,KATNAL1,TFPI,TMEM216,GMFB,MARCKSL1,COTL1,PITPNB,KMT2C,SOX4,ZNF91,MLLT10,YTHDF2,CXADR,TMCO1,INSIG1,FAM114A2,TNFRSF1A,ASB3,C2CD5,PIGN,FN1,VTA1,GPAT3,LAMTOR3,SMG7,PCSK7,ZFP36L1,ZIC2,TOX4,RNF141,CEP164,SUB1,SIPA1L3,TRMT13,VPS72,GLTP,ICE2,NRIP1,ZCCHC7,ZNF234,LAMC1,TRA2A,SETD2,HAUS6,PRDM1,TMEM241,CYB5B,TCF7L2,NR2F1,ISG15,SNAP23,TBPL1,HK2,CDKAL1,PFDN2,TBL1X,SH3PXD2A,PDSS2,PRKAR2A,TCF12,SNX27,PAPD4,SLC48A1,RBFOX2,PPP2R2A,PBX1,TBCCD1,DENR,RRN3,ANKRD13A,PPFIBP1,CBR4,SLC38A2,RNF2,BCAP29,AHCYL1,TSPAN14,KDM3B,PTBP2,FAM172A,RAB7A,CPOX,MANBAL,METTL2A,TMEM123,SLC35F2,CA5B,C1orf174,RAB10,TJAP1,COPS5,DUSP19,TMEM101,MED20,PPIL3,SMG1,KLHL24,AGO2,NSUN6,PPHLN1,IGF2BP2,CSNK1A1,FOXP1,BZW2,GART,ZNF561,ANXA7,IFIT5,STC2,SELT,CD44,LDLRAD3,TOP1,KDM5B,FOXN3,SLC35G1,PHACTR2,HSPA1B,MKX,CTIF,RERE,SRBD1,DSC2,SET,TBX3,TAF4,CUL2,CSRNP1,EIF2S1,TAF12,MBD6,RBPJ,PREPL,ZAK,KIF1B |
| 1.498e-05 | -11.11 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 2156 | 339 | 17775 | 2278 |
MYCBP2,GNB3,DPH1,SBF2,PRKCA,NUP160,SYNJ1,UBR5,GIPR,PDZD2,SREBF2,NEK6,PDS5B,SRRM2,FTSJ3,CDK6,SPAG6,NRAS,OSBP2,AP4B1,NFIA,C11orf80,TCEB3,EFHC1,SEMA3F,ABCC2,SON,GZF1,SKIL,DDX3X,TRRAP,ARL6IP5,HIC2,DNAH2,RIOK1,RUNX1,WDR66,HERC2,EP400,LARS2,PRPF31,SIRT7,TRIO,PIK3R4,PID1,SSR4,TGFBR2,ABCA7,PRKCE,CNST,TSPAN2,KIAA1671,APLF,USPL1,MCM5,CACNB2,MED24,PRMT5,CNOT4,MAP3K12,HMGCR,ADARB1,SCAF11,SIK3,IFRD1,RAPGEF4,ZNF512B,IMPDH2,ARID1A,ZNF655,ARIH2,PHF6,DYNC1H1,EPRS,LRP1B,EHMT2,SPEN,ZZEF1,RIOK3,DPEP1,MAP2K4,RTTN,RAB11FIP4,TRPM2,BIRC6,BTBD2,HFM1,PDK4,DDR2,PTPRG,FLNB,RPP30,PRKD3,SLX4,ASNS,TMEM184A,KDM2A,FMNL1,KMT2A,DENND1A,CDK12,PMS1,KMT2D,BRD4,PDK1,FAM111B,ADAM32,ATP6V0A1,KCNH3,TBC1D16,STK10,VPS53,MAT2A,FGFR1,VDR,PES1,TAF2,CAMK2D,SMARCC1,HIPK2,ZNF236,WDR7,RPS6KB1,TRAF3,MDN1,YEATS2,NCOR2,BRAF,XPC,TCF3,ZNF280C,FARS2,MLH1,KRI1,ABL1,PTRF,NISCH,COPS7B,ZNF710,SOX6,MS4A15,SPTAN1,CLK2,FAM120B,TMC7,PFKFB4,TTPAL,TSHZ1,DDX49,OXSR1,TRIB3,SRCAP,BAZ2B,IREB2,HELZ,ATM,APAF1,ADK,DOCK6,CORO2B,IPO4,STK4,CUL7,LETM1,ATRX,NF1,KIF5A,TFIP11,MFGE8,HECTD3,TRPM6,CSNK2A1,PLOD1,RNF43,BCOR,STK33,GIT2,MAP2K3,SMARCB1,ABL2,SRSF2,DHX33,ANKRD11,SLC35C2,PRKACB,SF3A1,PTPRK,CDC37,SRPK2,DSC3,DBN1,TNK2,DEAF1,SLC3A2,MIOS,ABCC4,ANK2,CDK4,ARRDC3,TFPI,GMFB,COL4A3BP,MARCKSL1,KSR2,BRCA1,MTHFD1L,LAMA2,SGK2,ZSCAN2,KMT2C,YTHDF2,DYRK1B,TMCO1,TP53BP1,CHD3,MKL2,CSMD3,COPS6,MAGI1,USP15,VIPR1,CLK1,TAF1,UBXN1,ALG8,SMG7,KIAA1958,ZNF358,MCAM,PDE10A,CTR9,SYNJ2,LRP3,POLR1E,N4BP2,CPSF3L,CAMKK2,LAMC1,USP49,ZBED4,OBSCN,WWC1,SUPT5H,SYT1,ACOXL,TCF7L2,PGD,PRPF40B,SYNCRIP,KIAA0355,FAT1,INTS5,TMEM117,TBCK,ZBTB24,USP7,CHMP2A,PCNT,CELSR3,SLC5A5,MYO7A,RIPK1,COBLL1,RSL1D1,TMEM177,RNF24,LPCAT3,PLXNB1,KDM1A,ZC3H13,RIOK2,VPS18,FARSA,CCDC50,RPS6KL1,FSIP2,PPFIBP1,IKBKB,ZNF142,HIRIP3,RNF2,MYH15,CORO1A,ADCK4,MET,CTC1,NARS2,EVL,COL5A2,SFSWAP,NUP214,UBR4,ALAD,DUS3L,TIMM17A,ATG7,SCARB1,SMG1,TMCC1,BCKDK,TNIK,MAP3K13,SUPT6H,RFX1,CAMK1,KLC4,ARFIP2,MAP1S,APRT,CSNK1A1,POGZ,GFM2,MAN1A1,PRKCH,DSG2,CPNE7,PKNOX1,RPS6KB2,DNMBP,ADAMTSL3,MON1A,KDM5A,SMARCAD1,TOP3A,TEX14,ARHGEF12,ARHGAP32,GPNMB,RHOT2,MKX,CDH24,DSC2,GPC2,AGTPBP1,USP20,RPS6KC1,XPO6,KIF1B,ZAK |
| 1.524e-05 | -11.09 | TBK1.DF_DN | MSigDB lists | TBK1.DF_DN | 272 | 60 | 17758 | 2279 |
SEPHS2,INSIG2,LETM1,NF1,SLK,MED13L,ATG2B,LIAS,RSF1,TTI1,SLC6A8,RLF,RSRC1,IGF2BP3,PRKD3,RRN3,COPS4,ZKSCAN1,PMAIP1,ZNHIT6,ANKRD11,POLR3B,GEMIN4,NRIP1,PLEKHA2,NAA35,CDK6,TERF2,SCAF11,TTPAL,DSC3,HMBOX1,COL17A1,COL5A2,TEAD1,ZNF654,MINA,DDX60,USP46,ANGPTL4,MTR,CXADR,DKK1,OSBPL1A,YTHDF2,GTF2A1,PMEPA1,LSM14A,CLEC16A,HIPK2,LUC7L3,ZNF557,ITGA2,SEMA3C,RPS6KB1,SCARB1,BLMH,FNBP1L,TSPAN5,SMG1 |
| 1.533e-05 | -11.09 | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | 142 | 37 | 17758 | 2279 |
CARS,CLK1,SEC24D,ID2,ZFP36L1,WDR26,CHAC1,DDIT4,ASNS,SLC7A11,PMAIP1,SLC38A2,ZEB1,ITGAX,CD44,CSGALNACT2,IFRD1,MSX1,SLC3A2,ATF4,GARS,TUBA1A,PSAT1,RB1CC1,ARID5B,MARS,PALLD,SOX4,KLF6,MBNL2,ANXA1,MGAT2,TRIB3,GADD45A,CLU,RPS6KC1,DDIT3 |
| 1.574e-05 | -11.06 | CHICAS_RB1_TARGETS_CONFLUENT | MSigDB lists | CHICAS_RB1_TARGETS_CONFLUENT | 531 | 102 | 17758 | 2279 |
ADAM19,RWDD1,PRDX6,MFGE8,MYH9,TUBB6,SPATS2L,ANKRD13A,JAG1,ECM1,ASNS,ARHGAP18,S100A10,RABGAP1L,JAZF1,SERPINH1,PXK,TRIM14,HN1,LAMA4,DPF3,GARS,FAM127A,EVL,TUBA1A,COL5A2,PPARG,THSD4,MSRB3,VIM,CAV1,COTL1,KCNH2,DDX60,WARS,OSBPL1A,SMAD3,SLC7A1,CAMK2D,AHNAK,GATA6,G6PD,ARL4A,SEMA3C,CLU,GALNT10,ANXA2,NRP1,BEND6,TPM1,TSPAN5,SYNPO,PKIB,RBP1,LPP,DCTN3,SARS,MCM6,FN1,CCDC53,STXBP6,GAS6,PHGDH,TGFBR2,MTUS1,CHN1,RGS17,PTRF,MCM5,SHMT2,ARHGAP1,PCK2,ERRFI1,GMDS,CD44,CAV2,RPL22L1,PRPS1,PLEKHG4,NAV3,PEA15,PXN,TRNP1,PSAT1,PRIM2,KCNMA1,ARID5B,PEAR1,RAP1GDS1,NXN,CORIN,EXOG,PALLD,EIF5B,SYT1,ANXA1,MTHFD2,POLE2,PDLIM1,BMP4,IFITM2,NR2F2 |
| 1.610e-05 | -11.04 | RAE1 (ribonucleic acid export 1) | protein interactions | 8480 | 106 | 32 | 16036 | 2270 |
USP7,WDR75,SART1,MYCBP2,CUL7,FN1,SF3A3,WDR26,FAM122B,PABPC4,IGF2BP3,FKBP1A,PRKD3,POLR3B,PABPC1,MPST,SEH1L,HSD17B14,SF3A1,CDC37,DDX24,MIOS,PRIM2,POLA1,LGALS1,NUP214,POLR3A,UBC,LSM14A,POLR3E,USP11,COPS6 |
| 1.613e-05 | -11.03 | ELVIDGE_HYPOXIA_UP | MSigDB lists | ELVIDGE_HYPOXIA_UP | 164 | 41 | 17758 | 2279 |
KLHL24,ZNF292,INSIG2,EGR1,SLC2A1,BCOR,NOL3,BHLHE40,PRKCA,FAM13A,RLF,FLNB,DDIT4,DST,PTRF,GPR87,STC2,MET,SAMD4A,RBCK1,KRT7,PDK1,TRA2A,ZNF654,ATXN1,AKAP12,CAV1,KLF6,ANGPTL4,PLIN2,SRCAP,PXDN,DSC2,KDM4B,SRD5A3,HK2,AHNAK2,PAM,SCARB1,RBPJ,YEATS2 |
| 1.668e-05 | -11.00 | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN | MSigDB lists | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN | 192 | 46 | 17758 | 2279 |
MCM6,LARS2,TCF3,TMEM183A,PABPC4,NRF1,PHKA1,USPL1,ZDHHC6,SHMT2,GEMIN4,PRMT5,YARS,FTSJ3,GARS,GPHN,NARS,SKIV2L2,POLA1,EPS15L1,RAP1GDS1,RNH1,RANGAP1,MCM2,DKC1,PLCB1,EHBP1,PDE3B,HERPUD1,RPA1,SLC39A14,ZFAND3,GLS,KIDINS220,TRAP1,HERC1,LEMD3,ZNF236,AHNAK2,TRAF3,HMBS,BLMH,PDSS2,XPO6,C7orf26,COG5 |
| 1.756e-05 | -10.95 | HALLMARK_MYC_TARGETS_V1 | MSigDB lists | HALLMARK_MYC_TARGETS_V1 | 198 | 47 | 17758 | 2279 |
SRM,MCM6,DDX18,PRPF31,RSL1D1,HDDC2,PABPC4,NOP56,CAD,EIF2S2,SRSF2,NOP16,MCM5,MYC,ETF1,SSBP1,RAN,POLE3,FBL,PABPC1,SERBP1,SF3A1,RFC4,IFRD1,APEX1,EIF3J,CDK4,GNL3,LDHA,PSMA1,IMPDH2,MCM2,ODC1,CLNS1A,UBE2E1,PWP1,EPRS,HPRT1,SYNCRIP,SMARCC1,HNRNPR,COPS5,SET,ACP1,EIF2S1,NCBP2,NOLC1 |
| 1.837e-05 | -10.90 | PHD | smart domains | SM00249 | 91 | 28 | 9131 | 1249 |
DPF3,ASH1L,PHF3,KMT2D,KDM5B,KMT2E,BAZ2A,KDM5A,DPF2,RSF1,KMT2C,CHD5,TRIM66,PHF6,MLLT10,BAZ1A,NSD1,BAZ2B,KDM2A,KDM4B,TAF3,CHD3,INTS12,KDM5C,KMT2A,FBXL19,KDM4C,KAT6A |
| 1.887e-05 | -10.88 | adenoid_cystic_carcinoma | COSMIC cancer mutations | adenoid_cystic_carcinoma | 1159 | 196 | 17775 | 2278 |
SLC37A3,CDCP1,MVK,ATRX,CSNK2A1,BCOR,PRKCA,MGA,MAP2K3,ZNF804A,ABL2,PDZD2,ZFHX3,RNF111,CHD2,CEP135,FXN,ZMYM2,CDK6,TRIP13,PRKACB,SRPK2,FAM184A,PTPRK,FLNC,CHD9,TNK2,NRAS,HARS,SIRT6,CDK4,ARRDC3,CUX1,KSR2,BRCA1,KMT2C,SOX4,TMEM206,UBTF,GEMIN5,AHNAK,BRCA2,TRRAP,SUFU,TOM1L2,TP53BP1,CSMD3,RUNX1,MAGI1,SYNPO,PTPN14,SEPHS2,AK2,FOXO1,ANKRD17,CLK1,KHDRBS1,PAX2,TRIO,MAPK8IP3,PIK3R4,ZFP36L1,RLF,C1orf50,TGFBR2,CD226,ARID1B,ABCA7,RBM20,RNF40,PI4KB,DHX37,ATXN2,GTF2H1,GTF3C3,ALDH18A1,MAP3K12,TOMM34,ANGPT2,MTHFD1,CAMKK2,RB1CC1,PRDM16,ARID5B,TYW1,JMJD1C,TBXAS1,RAP1B,RYR2,OBSCN,ARID1A,SUPT5H,SLC26A11,EXOC6,ZNF783,DAGLA,SYCP2L,ASCC3,LRP1B,BICD1,FAM135A,SPEN,ZZEF1,HK2,CNDP2,PDLIM5,PRKAR2A,ARHGAP10,MAP2K4,SDSL,CYLD,BIRC6,CELSR3,PDK4,PTPRG,CORO6,GBF1,DDX60L,STAM,PLXNB1,PHC2,RPP30,ZNF827,ACD,FMNL1,RPS6KL1,FGGY,SLC38A2,GSTA4,CMPK1,MET,KMT2A,MAML3,SEC24A,SSFA2,PDK1,ADAM32,MRRF,AKAP13,GALK2,ENC1,EDEM2,STK10,FGFR1,TJAP1,HIPK2,RPS6KB1,TROVE2,TRIM36,ZNF507,HMGA2,TNIK,BRAF,MAP3K13,DBF4,SF3A3,ATF7IP,CCDC7,IP6K2,IKBKAP,ENOX1,CSNK1A1,FOXO3,IQGAP2,ABL1,PRKCH,SACS,LARP4B,ERRFI1,SOX6,RPS6KB2,KDM6B,ADAMTSL3,MON1A,CRIM1,AGPAT4,KDM5A,RSBN1,PALLD,PDE3B,C8orf33,PIK3CB,CENPP,SRCAP,NSD1,TRIB3,PXDN,TMEM237,DAGLB,HERC1,DNAJC12,ATM,MYOM2,RPS6KC1,GPATCH4,DDIT3 |
| 1.895e-05 | -10.87 | GCM_NCAM1 | MSigDB lists | GCM_NCAM1 | 122 | 33 | 17758 | 2279 |
ANKRD17,RBFOX2,SMAD7,KIF5C,QSER1,IKBKAP,FOXO3,FAM8A1,SPIRE1,UBE3A,RABGAP1L,NISCH,DCTN4,GSTA4,RAN,CELF1,ZMYM2,PKNOX1,PTBP2,TSPYL4,TEAD1,ZFP14,MARCH6,CRYBG3,EIF4ENIF1,SPAG9,TMEM237,KIDINS220,SUFU,CEP170,KIF1B,DMTF1,CORO2B |
| 1.905e-05 | -10.87 | transcription factor binding | molecular function | GO:0008134 | 516 | 101 | 16491 | 2164 |
USP7,TCF12,ZNF516,ID1,TRERF1,RBFOX2,PPARGC1B,SMARCA4,PBX1,BCOR,SIRT2,PELP1,KDM1A,SKI,SMARCB1,CAMTA2,PPID,DHX33,ZNHIT6,ZEB1,HYAL1,KAT8,PRAME,ATF4,PPARG,NFIA,HDAC8,MED16,CAV1,MEF2D,SPOP,DOT1L,SMAD3,VDR,DDX3X,MSX2,RBBP8,SUFU,IKZF4,GATA6,TP53BP1,PER1,KLF4,DNAJA3,HIPK2,E2F4,ARNTL,ATG7,FUS,RUNX1,PDCD11,SETD6,YEATS2,MEF2C,HMGA2,NCOR2,INSIG2,EGR1,FOXO1,TRIP6,TAF1,PAX2,TCF3,HES6,BHLHE40,FOXO3,MAD2L2,SNW1,MLX,HR,MYC,MED24,FBL,NRIP1,POLR1E,PAXBP1,PRDM16,JMJD1C,SMARCD3,OASL,FOXC1,NOP58,TCF7L2,MKX,APBB3,NSD1,MYBBP1A,GTF2A1,HIF1A,SPEN,CDK9,TBX3,BCAS3,PURB,TBL1X,RBPJ,TAF12,NCOR1,DDIT3,STK4,KAT6A |
| 1.922e-05 | -10.86 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | 193 | 46 | 17758 | 2279 |
CCDC58,ST6GAL1,FANCD2,SPATS2,RNASEH2B,FLNB,DDIT4,UCHL5,MYC,JAZF1,XRCC2,IPP,BCAP29,ZNF518B,CDK6,TRIP13,MYB,CEP128,RFC4,MPP6,PSAT1,SKAP2,PSPC1,GNL3,PSMC3IP,HSH2D,CPT1A,NOP58,CENPP,TAMM41,EXO1,OXSR1,PWP1,ATAD5,MTHFD2,RAD18,SET,SRFBP1,UMPS,FKBP5,ADK,BMI1,SPOCK2,SYNPO,GCSH,MEF2C |
| 1.922e-05 | -10.86 | GSE17721_0.5H_VS_12H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_CPG_BMDM_UP | 193 | 46 | 17758 | 2279 |
SLC12A7,WDR75,MYCBP2,NDUFA5,LETM1,FN1,MYO7A,CERS5,CD99L2,CHCHD10,APRT,GYG1,PRKD3,ATP5G2,ATG3,NDRG4,BCAP29,CORO1A,POLE3,MAP3K14,MGLL,SRPK2,CDK4,RAB7A,PPP1R21,LDHA,LGALS1,NXN,IMPDH2,SOX4,TPRA1,SLC50A1,CLNS1A,TIMM44,BATF3,RPA1,ALAD,PER1,CUL2,LARGE,SCARB1,RWDD2B,HMBS,DHCR7,SYNPO,AP2S1 |
| 1.930e-05 | -10.86 | BAELDE_DIABETIC_NEPHROPATHY_DN | MSigDB lists | BAELDE_DIABETIC_NEPHROPATHY_DN | 420 | 84 | 17758 | 2279 |
ZNF516,PRDX6,ACTG1,PAFAH1B1,ACTR3,KIAA0232,MYH9,GYG1,SSBP2,FOSL2,ST3GAL6,BIRC2,DST,RABGAP1L,GSTA4,PRKACB,DDN,HSPA5,GMFB,PCMT1,ATXN1,TMEM123,MCL1,VIM,CAMSAP2,ODC1,WARS,CXADR,TOM1L2,SMARCC1,CHD3,CLEC16A,LUC7L3,PAM,VPS13D,SEMA3C,NFASC,SYNPO,SPOCK2,PTPN14,PARD3,SERINC5,MCM6,SLK,PDE4B,LETMD1,RCAN1,TRIM22,IQGAP2,NAMPT,SUB1,NEBL,CACNB2,RDX,GMDS,AKAP11,TOMM34,FAM98A,FGF9,CRIM1,TSPYL4,ARID5B,EIF4A2,FERMT2,RSBN1,GPNMB,PALLD,TRIM37,USP46,FOXC1,ISG15,ANXA1,IRS1,FBXO21,MTHFD2,SERINC1,GADD45A,VCAN,FAT1,SET,PREPL,PDLIM5,FNBP1L,CORO2B |
| 1.946e-05 | -10.85 | DNA Repair | REACTOME pathways | R-HSA-73894 | 306 | 68 | 8202 | 1117 |
USP7,POLB,ASCC1,CUL4A,GTF2H2C,FANCD2,RCHY1,BRE,SLX4,COPS4,XRCC2,RNF111,ATRIP,OGG1,SPIDR,PRPF19,RFC4,RFC3,SIRT6,PARP2,EYA3,SUMO3,BRCA1,HIST1H2BL,EXO1,BRCA2,RBBP8,KDM4B,RAD18,TP53BP1,COPS5,H2AFX,RAD51B,EME1,NFRKB,COPS6,BRCC3,XRCC4,MUTYH,HERC2,XPC,FAN1,MLH1,RMI1,MAD2L2,ABL1,ELL,COPS3,GTF2H1,TIMELESS,COPS7B,GTF2H3,APEX1,POLK,TOP3A,USP10,LIG4,HIST1H4J,POLR2A,ISG15,UBC,RPA1,ASCC3,POLE2,ALKBH3,PALB2,MSH3,ATM |
| 1.947e-05 | -10.85 | N-methyltransferase activity | molecular function | GO:0008170 | 80 | 25 | 16491 | 2164 |
ASH1L,KMT2D,SETD1B,KMT2E,RNMT,SETD2,EHMT1,METTL15,SETD7,MEN1,KMT2C,DOT1L,METTL16,NSD1,EHMT2,SUV39H2,PEMT,CAMKMT,FBL,PRMT5,KMT2A,SETD6,PRMT3,SMYD3,CARM1 |
| 1.948e-05 | -10.85 | MODULE_102 | MSigDB lists | MODULE_102 | 18 | 10 | 17758 | 2279 |
HPRT1,GART,ADSL,UMPS,APRT,CMPK1,IMPDH2,ADK,PRPS1,MTHFD1 |
| 1.952e-05 | -10.84 | GAANYNYGACNY_UNKNOWN | MSigDB lists | GAANYNYGACNY_UNKNOWN | 72 | 23 | 17758 | 2279 |
TCF12,MINK1,PAPD4,SEC24D,TLE3,FOXN3,UBE2K,ONECUT2,SLC1A1,NR2F1,BRE,NAV1,CCDC50,SHC1,INTS5,TRMT2A,JOSD1,IGF2BP1,NR2F2,MID1,SPOCK2,C15orf41,STK4 |
| 1.954e-05 | -10.84 | SUB1 (SUB1 homolog, transcriptional regulator) | protein interactions | 10923 | 66 | 23 | 16036 | 2270 |
SART1,FN1,TAF1,HSPA5,CSNK2A1,RANGAP1,SUPT5H,CHD5,ABCF1,POLR2A,ABL1,TSR1,SUB1,KPNA1,EIF2S2,SRSF2,TP53BP1,BANF1,SET,NOLC1,SRRM2,TROVE2,TERF2 |
| 2.005e-05 | -10.82 | MORF_RFC4 | MSigDB lists | MORF_RFC4 | 149 | 38 | 17758 | 2279 |
MCM6,DDX18,KHDRBS1,XPO7,POM121,PABPC4,HDDC2,NDUFB3,CAD,EIF2S2,MRPS27,TNPO3,SHMT2,SSBP1,YARS,TRIP13,NUDC,IFRD1,RFC4,RFC3,GARS,SKIV2L2,R3HDM1,MARS,MCM2,DKC1,SERP1,ABCF1,TARS,CHAF1A,RPA1,EPRS,TRRAP,HNRNPR,CEBPZ,SET,GPN1,NCBP2 |
| 2.014e-05 | -10.81 | AA_TRNA_LIGASE_I | prosite domains | PS00178 | 15 | 9 | 11866 | 1504 |
EPRS,RARS,WARS2,LARS2,RARS2,MARS,VARS,YARS2,WARS |
| 2.034e-05 | -10.80 | IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR | 496 | 96 | 17758 | 2279 |
VMA21,ZNF76,SPRED2,ASCC1,DDX18,NDUFAF2,LAGE3,RIPK1,SMARCA4,TMEM177,BCOR,LCLAT1,STAM,FDX1,MRPS30,METTL16,ABL2,LYPLAL1,YLPM1,PPID,ATP5G2,PPFIBP1,MRPS27,SOCS6,DTNBP1,CPSF3,ZNRD1,CDK6,PLEKHA4,CTC1,MCEE,METTL1,WDR36,TRIM13,MPP6,RBCK1,ABCC4,RNMT,CDK4,CUX1,MINA,NLN,GALK2,KRTCAP2,NUDT15,RBM28,FGFR1,TMEM206,HLA-DMA,RAD18,FAM206A,METTL6,ALKBH1,PRPF4,NOLC1,FBXO45,TRAK1,IP6K2,RBM19,SSR4,RPS6KA5,CHD5,RSRC1,BZW2,PEX7,GART,CTNNBL1,TMEM161A,KDELC1,SHMT2,DDX31,LDLRAD3,GMDS,PPA1,SNAPC5,MTHFD1,MYB,DDX28,GPHN,C19orf43,ELP3,WDR18,EXOG,CYB5B,ZRANB3,MFN2,MGAT2,RETSAT,L3MBTL3,SRP68,CUL2,UMPS,MACROD1,DHCR7,GCSH,GPATCH4 |
| 2.065e-05 | -10.79 | RNA polymerase binding | molecular function | GO:0070063 | 36 | 15 | 16491 | 2164 |
PAF1,RRN3,ELP2,ELP3,AGO2,WAC,ZNF326,WDHD1,CTR9,ANP32B,IKBKAP,SCAF8,CDC73,SMYD3,NEDD4 |
| 2.079e-05 | -10.78 | stomach-adenocarcinoma | COSMIC cancer mutations | stomach-adenocarcinoma | 4272 | 627 | 17775 | 2278 |
GGT1,CDCP1,CNTNAP3,SBF2,CSPP1,HLTF,CCNL2,HMOX2,NUP160,SYNJ1,AMBRA1,PCDH7,PDZD2,ZFHX3,THAP4,LETM2,RABGAP1L,MAD1L1,ZNF148,HRG,SRRM2,PPM1K,HMBOX1,NRAS,RNMT,WLS,PTPRM,EHMT1,KIF15,AKAP12,PLEKHM3,RBM28,PYCR1,AHNAK,BRCA2,LRRC40,DIRAS1,CARS,HERC2,EP400,KHDRBS1,TRIO,RSF1,CDC73,PITPNM1,SLC1A1,ABCA7,RSPRY1,UBE3A,CNST,CACNB2,MRPL21,CALN1,MAP3K12,AGL,NOM1,HMGCR,GTF2H3,IFRD1,COL17A1,STAG1,KCNQ3,EIF4A2,ZNF512B,EVI5,ONECUT2,ABCF1,NCDN,DYNC1H1,VPS13C,LRP1B,GTF2A1,LEMD3,CNOT6,BPNT1,WDR33,ARHGAP10,SGSM3,GALE,SPRED2,RAB11FIP4,ABCA3,TRERF1,DDX18,NPAS2,ATP6V1A,ACTR3,MAB21L3,DDR2,MYH9,SAFB2,RPGRIP1L,ZBED2,ZSWIM7,ABCA12,TBC1D22A,GSTA4,CEP63,DENND1A,LSM10,LYST,PMS1,ARHGEF10,SLCO6A1,DSP,FKBP3,PDE8B,ZFAND3,TAF2,ARHGAP21,WDR7,PAM,ZBTB11,YEATS2,MORC2,INSIG2,ATG2B,RNASEH2B,RSRC1,MBNL1,POLR3D,CFDP1,RAPGEFL1,ZNF710,HNRNPM,NUDC,C21orf58,FAM98A,ZC4H2,ZC3H18,FRA10AC1,RSBN1,FAM126B,PPIP5K2,PDE3B,UBC,TOE1,RARS,SRCAP,NSD1,BAZ2B,POLE2,PTPN4,BMP4,GPAM,CORO2B,GPATCH4,KDM4C,CYP24A1,GPBP1L1,POLR1A,RNF43,TTI1,COX10,GIT2,SCAF8,ABL2,ARHGAP18,COPS4,ANKRD11,METTL8,PTPRK,SF3A1,CDC37,VPS13B,FAM184A,FLNC,DSC3,FMNL3,GCNT2,SKIV2L2,PPARG,ANK2,MED27,LAMA2,BRCA1,KCNH2,ODC1,KIF16B,PEX1,TCF7L1,ZNF622,MSRA,TP53BP1,CHD3,TECPR2,CCDC146,SGSM2,TSEN2,MAGI1,BEND6,RNF214,SARS,MCM6,FAN1,MAPK8IP3,ZFP36L1,ARID1B,DOPEY1,RNF40,ZNF358,ABCA5,PDE10A,MBD2,PPIL2,TIMELESS,CTR9,SYNJ2,GMDS,ALDH18A1,TRAPPC9,LAMC1,IFT43,SETD2,ZNFX1,SUPT5H,ACOXL,VAC14,GRIK4,FAM135A,SPAG9,TTC38,TBPL1,SNX24,ZNF430,CASS4,GGT7,NAPA,USP7,CYLD,PAPD4,LPCAT2,SLC2A1,SSBP2,DENND3,PPP1R9A,FDX1,CAD,NRF1,UBR1,FGGY,FSIP2,HIRIP3,CCDC40,ETF1,BCAP29,ANO8,MYH15,AHCYL1,CASP10,KDM3B,SKIV2L,SEC24A,WDR36,ARHGAP17,PCGF3,EVL,GLTSCR2,THSD4,VIM,AKAP13,ENC1,NUP214,EIF3H,BTBD11,EXO1,RANBP2,ZNF333,TIMM17A,ITGA2,ATG7,INTS9,EIF2B3,MUTYH,PARD3,ATXN7L2,ESCO1,AUH,FAM46B,VARS,RBM19,POGZ,BZW2,ZNF594,IQGAP2,NDUFV1,SACS,ANXA7,CWC27,DDX31,POLR1B,C12orf4,SNAPC5,ADAMTSL3,MON1A,SMARCAD1,ABCF2,TEX14,TOP3A,DHX34,PEAR1,FERMT2,ARHGEF12,RANGAP1,C11orf49,RHOT2,CHCHD6,ARMC3,SMPDL3B,NEU1,MKX,POLR3G,CENPP,CDH24,SRBD1,L3MBTL3,ADAT2,CSRNP1,BCAS3,MSH3,TAF12,ITGB4,RPS6KC1,KIF1B,CGN,MYCBP2,CUL4A,LUZP1,TMEM109,ENAH,PRKCA,GABPB2,UBR5,AARS,LPIN1,S100A10,RNF111,CEP135,MEIS3,CSGALNACT2,SPAG6,ACADS,SLC38A6,NR6A1,EYA3,TCEB3,SEMA3F,SON,SAP30BP,SPOP,SH3GL1,GNAI1,GZF1,SKIL,DDAH2,TRRAP,SH3RF1,LSM14A,LUC7L3,VPS13D,DNAH2,SPOCK3,PTPN14,EFNB2,WDR75,CELSR1,LARS2,GTF2IRD1,CCDC47,MTUS1,IGF2BP3,TECTA,NAV1,ENTPD5,ASAP1,USPL1,MFAP2,LPCAT1,TERF2,SCAF11,SIK3,EXOSC2,RREB1,SYNGAP1,PCCA,RAPGEF4,ARID1A,PLCB1,EHBP1,SLC26A11,MTR,ATP9B,CAT,KIDINS220,NSF,HIF1A,VCAN,SPEN,ZZEF1,D2HGDH,BIVM,ZCCHC6,DPEP1,UMPS,NCOR1,CNDP2,SMYD3,RTTN,HFM1,PLEK2,PTPRG,SLC25A44,HNRNPA3,FLNB,PDE3A,IGSF1,NOP56,FLAD1,SLX4,GLYR1,SOCS6,DTNBP1,MRPS27,TTC3,SERPINH1,KMT2A,PLEKHA4,CDK12,C18orf21,ZCCHC14,BRD4,MPP6,GON4L,PREX1,PNN,ERC1,DHX57,HSD3B7,HTR7,SMARCC1,ZNF236,ACP1,MDN1,MID1,NOSTRIN,SSH2,BRAF,UTP14A,C10orf2,NFX1,SLC25A12,MYNN,IKBKAP,FAM8A1,FOXO3,ABL1,NEBL,UPF2,CELF1,LARP4B,ERRFI1,PLEKHG4,MBTPS2,NAV3,FAM120B,TMC7,TTLL5,ZFYVE1,WDFY3,BMS1,PACS1,GUF1,ZDHHC11,IREB2,DDX50,SVIL,ATM,MYOM2,APAF1,BRWD3,IPO4,SLC37A3,IMMP2L,ZNF76,UBN1,NF1,ATRX,FANCD2,TRPM6,PLOD1,ZNF107,SLC29A1,SNAPC4,AHCYL2,DST,SRPRB,ZNF804A,ANAPC1,CNIH3,MYH3,GPATCH1,ZEB1,HCFC2,OGG1,CARM1,SRPK2,ZBTB17,SESN2,TRIM13,TXLNG,MINA,TCTN1,ST3GAL5,TIMM44,GEMIN5,TMEM132B,UBTF,EPN2,TMCO1,CC2D1B,MKL2,CSMD3,ABCC3,GALNT10,VIPR1,CHST11,TAF1,VTA1,MED13L,SMG7,EVPL,C11orf54,MCAM,ATXN2,SEMA3D,ZCCHC7,PRF1,NRIP1,HSD17B14,MTHFD1,PPAT,ZBED4,JMJD1C,CORIN,UBE2E1,EXOC6,KIAA0355,INTS5,CDKAL1,TMEM117,TBCK,ZBTB24,DMXL2,TCF12,CHMP2A,ASH1L,PCNT,PSTPIP2,PIBF1,GBF1,ZSCAN5A,ZC3H13,VPS18,CAMTA2,FHIT,ADCK4,ITGAX,CPSF3,MET,VCL,GNG5,COL5A2,FAM172A,PARP2,NLN,TOR1AIP2,ATP8B2,RAB10,RAD54B,TPK1,ARMC4,ADNP,ARNTL,SRFBP1,FKBP5,DISP1,NFRKB,ECHDC1,SMG1,DNAJA4,C17orf80,SUPT6H,DYM,KLC4,PDE4B,CLSTN2,LETMD1,ATF7IP,SEMA3E,CCDC7,GFM2,PIP4K2A,SFI1,IL17RE,PRKCH,PEX7,DCTN4,DSG2,STC2,TTC17,ERI3,MARCH9,KDM5A,PSPC1,SULT4A1,ASAP3,ARHGAP32,PDE2A,EIF5B,TMEM187,TARS,RERE,CTIF,MPP7,TATDN1,PREPL,POLR1C |
| 2.175e-05 | -10.74 | lung-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-squamous_cell_carcinoma | 15429 | 2038 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,SLC6A8,ZNF44,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,KLHL23,RNMT,LIMA1,EXOC6B,UPP1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,TPM1,VASH2,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,STAG1,ALG6,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,NME7,PDLIM1,RPL28,EHMT2,TRAP1,FGFBP1,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,SDSL,RAB11FIP4,GTF2H2C,C16orf95,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,ZMAT2,CBWD5,UBL5,MCM9,RPGRIP1L,CD96,ESAM,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,ZC3H3,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,EIF3J,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CEP170,METTL2B,CATSPERG,BAG1,MAPT,RAB30,MORC2,COMMD10,HMGA2,SHQ1,XRRA1,ATG2B,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,NOP16,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,SPTAN1,TTPAL,VPS37A,DDX24,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,MRPL36,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,PHF5A,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,MARCKSL1,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,ARID1B,SPIRE1,SUB1,RNFT2,MLX,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,OLFM2,PAPD4,SUCLG1,ARID2,OSBPL9,NTSR1,SLC2A1,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,FDX1,PLXNB1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,SLC25A20,ADH5,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,C22orf34,ABCF2,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,C8orf33,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,ZNF32,RBPJ,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,LRP5L,GABPB2,LPIN1,EXOC1,S100A10,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,DENND4A,SON,DDX60,TMEM206,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,CAV2,RTFDC1,FDFT1,EXOSC2,IFNGR2,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ZNF850,PHF6,ATP9B,ASCC3,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,NUBPL,DECR1,SLX4,ASNS,ARMC6,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,SERP1,SNCA,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,XRCC4,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,SDCBP2,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,TMEM126B,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,GUF1,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,EIF3C,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,TMEM216,MINA,KSR2,MTHFD1L,PITPNB,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,SCART1,ZCCHC8,VTA1,UBXN1,PCSK7,SMG7,QSER1,EVPL,TIMM10,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,CCDC124,ZCCHC7,PRF1,LRP3,ATP6V0D1,AKAP11,HSD17B14,MTHFD1,MSI2,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,IFITM2,FNBP1L,TBCK,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,SNTG2,FHIT,ADCK4,ITGAX,VCL,GNG5,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,ANTXR2,PRAME,GRHL3,ATXN1,POU2F1,MRRF,METTL15,EDEM2,UBR4,ARMC4,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,DUSP19,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,KLC4,CMTM8,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,CHCHD10,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,MFHAS1,FAM49A,PEX7,SCN1B,SEC24C,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,SERINC1,WDR35,AGTPBP1,ANKRD30BL,POLR1C,NFKBIB,ZSWIM6,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,FAAH2,RABGAP1L,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,RBP1,LPP,MEF2C,TNNC1,HERC2,CARS,EP400,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,ANP32B,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,PEA15,BDNF,GTF2H3,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,ACTR3,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,NT5C,GSTA4,CEP63,TMEM136,MTHFD2L,LSM10,MALL,GARS,KRT7,STAMBP,FAM111B,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,WDR37,JMJD6,AKT1S1,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,PVRL3,ACAP3,ARHGAP1,HNRNPM,SOX6,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,DDX49,FOXC1,CASC1,RPA1,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,PLPPR2,SLCO5A1,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,XRCC2,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,ZNF124,SLC3A2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,SEPHS2,NOMO3,SARS,AOC3,OXNAD1,MCM6,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,TRIM15,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,FAM135A,ITPRIPL1,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,RSL1D1,PPP2R2A,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,IKBKB,ZDHHC6,C15orf40,HIRIP3,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,EVL,NARS,GLTSCR2,THSD4,CPOX,C1QTNF1,MANBAL,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,USP36,TMEM186,BTBD11,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,NFASC,ZNF18,PUS1,SEPT5,ZNF589,PPIL3,PKIB,ATXN7L2,UNC13D,MAP3K13,FAM46B,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,FAM50A,NDUFV1,SACS,ANXA7,ZNF561,CWC27,IFIT5,HIST2H3D,PRICKLE2,GREB1,DDX31,SELT,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZNF654,ZMYM5,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,GCSH,POLB,MYCBP2,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,AARS,UBR5,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,PRADC1,MEIS3,CEP135,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,CCDC53,OPHN1,GTF2IRD1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,ADARB1,SCAF11,USE1,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,SERF2,UBAP1,PMEPA1,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,PPDPF,AMOTL1,TRPM2,RWDD1,LIN28B,SPATA2L,ZBTB37,URB2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,FOSL2,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,CHD7,TERF2IP,FLAD1,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,HTR7,YIPF2,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,SCAMP3,CA11,UTP14A,TTC27,C10orf2,MRI1,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,MAD2L2,NEDD4,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,EXOSC4,LARP4B,PLEKHG4,MBTPS2,FAM120B,PFKFB4,TSHZ1,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,ECH1,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,RNF138,MYOM2,PGAM5,BRWD3,RABEP1,SLC43A1,LRRC41,STK4,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,FANCD2,TRPM6,ZNF107,PLOD1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,MRPS30,WNT2B,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,ZNHIT6,GPR87,ANAPC10,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,LONP1,PRKACB,TRIP13,TIMM50,LAMA4,ZBTB17,GPM6A,TXLNG,ZNF680,SLC38A1,CMIP,LVRN,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,ZNF397,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BUD31,SEMA3D,CCDC112,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TBXAS1,WBSCR22,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,ANKRD20A4,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,MMRN2,CELSR3,SLC5A5,MYO7A,ST7L,SLC9B2,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,RAB10,PUSL1,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SLC25A11,SRFBP1,SCARB1,DISP1,HEATR1,USP11,ECHDC1,TSPAN5,KLHL24,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,PPP1R1C,SFI1,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,CLDND1,TTC17,UTS2,AMOT,DMRT1,MSX1,TEAD1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,SYMPK,NAPEPLD,TARS,RERE,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,NCBP2,ZRANB2,MBD6,PREPL,TATDN1,MMP16,ZAK,ARHGAP27,SLC16A10,HRH1 |
| 2.192e-05 | -10.73 | THUM_SYSTOLIC_HEART_FAILURE_DN | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_DN | 211 | 49 | 17758 | 2279 |
NDUFA5,FAM208B,CDC42EP2,UBN1,VTI1A,SBF2,ATF7IP,NBEAL1,CSNK1A1,GIGYF2,PPP1R9A,PDZD2,ZSWIM7,CACNB2,PPFIBP1,CFDP1,WDR60,ZNF148,TTC3,PLEKHA2,ZCCHC7,PPM1K,SCAF11,FAM98A,DPF3,WDR61,AKAP8L,RREB1,SLC38A1,FOXN3,TRA2A,ARHGEF10,NLN,FAM126B,LAMA2,CCDC28B,MLLT10,SPAG9,HSDL2,PER1,SDCCAG8,POLR3E,WDR73,VPS13D,FNTB,PDLIM5,TESC,N4BP2L2,MAPT |
| 2.193e-05 | -10.73 | aa-tRNA-synth_I_CS | interpro domains | IPR001412 | 15 | 9 | 18293 | 2341 |
EPRS,RARS,WARS2,LARS2,RARS2,MARS,VARS,YARS2,WARS |
| 2.195e-05 | -10.73 | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | MSigDB lists | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | 459 | 90 | 17758 | 2279 |
PHF3,LIN28B,BIRC6,CNTNAP3,PDK4,ADAMTS6,ENAH,FAM122B,ARSJ,LCLAT1,TOM1L1,CHD7,CAMTA2,JAZF1,SLC38A2,MMP14,ETF1,RAN,CARM1,SRPK2,CHD9,TRIM13,NR6A1,BAZ2A,RNMT,EYA3,ARRDC3,ATXN1,DHX57,MAT2A,YTHDF2,GLS,DDX3X,GATA6,PAM,HIC2,RPS6KB1,RUNX1,MAPT,LPP,TMCC1,MINK1,SMAD7,ZFP36L1,ZIC2,IGF2BP2,WDR37,BHLHE40,RLF,FOXP1,CDC73,SPIRE1,POM121,SFR1,FKBP1A,PRKCE,DOPEY1,SEC24C,CACNB2,LPCAT1,FMNL2,SOX6,ADARB1,STAG1,CRIM1,KCNMA1,USP42,EIF4A2,RAP1B,MEX3B,RSBN1,FAM126B,PALLD,PPIP5K2,KLF6,MBNL2,ZNF655,KPNA1,BAZ2B,LEMD3,TBPL1,PURB,PPP1R12B,RBM26,TBL1X,PSAP,GGT7,PDLIM5,MB21D2,LMBRD2 |
| 2.211e-05 | -10.72 | GSE360_L_MAJOR_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_T_GONDII_MAC_DN | 194 | 46 | 17758 | 2279 |
SRM,NCOR2,MCM6,TCF3,SLC2A1,MED13L,ARFIP2,APRT,FAM13A,FAM8A1,POM121,HDDC2,CIAPIN1,IGF2BP3,FLAD1,ABL1,SERPINH1,ERI3,PRMT3,ZNF629,PMS1,RFC4,ZNF124,PDE4A,APEX1,ITPA,HARS,ZBED4,IMPDH2,MCM2,DKC1,CHAF1A,ATP5D,MFN2,EPRS,TRRAP,HNRNPR,TECPR2,ACP1,NFRKB,MDN1,IQSEC2,NOLC1,DHCR7,SLC43A1,HS2ST1 |
| 2.227e-05 | -10.71 | MORF_EIF3S2 | MSigDB lists | MORF_EIF3S2 | 240 | 54 | 17758 | 2279 |
SRM,AK2,PRPF31,KHDRBS1,RSL1D1,VARS,XPO7,POM121,PABPC4,CAD,NDUFV1,EIF2S2,SREBF2,MRPS27,SSBP1,POLE3,FBL,YARS,GNG5,SERBP1,NUDC,RFC4,IFRD1,DEAF1,SLC3A2,ATF4,SKIV2L2,NPM3,WDR18,LDHA,PCMT1,PSMA1,IMPDH2,MCM2,DKC1,SERP1,DDX49,TARS,POLR2A,ARIH2,CLNS1A,EIF3H,CHAF1A,ATP5D,EPRS,HNRNPR,TIMM17A,COQ9,SET,CEBPZ,ACP1,GPN1,NDUFS5,TROVE2 |
| 2.234e-05 | -10.71 | carbohydrate derivative binding | molecular function | GO:0097367 | 2195 | 350 | 16491 | 2164 |
ACTG1,DDX19A,AARS2,NAT10,TUBE1,HLTF,PRKCA,RAC3,AARS,MMP7,NEK6,SYN2,PDS5B,SUCLG2,ME1,DPH6,CHD2,HRG,CDK6,NRAS,GNL3,KIF15,ABCC2,MCM2,DDX60,GNAI1,DDX3X,DNAH2,RIOK1,DIRAS1,RUNX1,NRP1,SPOCK2,SPOCK3,CARS,ADGRE2,EP400,DROSHA,LARS2,SLK,TRIO,AK6,PIK3R4,TGFBR2,PDCD5,CHD5,YARS2,ABCA7,PRKCE,DDX56,PI4KB,DHX37,MCM5,MAP3K12,PRPS1,SIK3,DDX28,MYO10,POLA1,PCCA,EIF4A2,RAPGEF4,IDH3G,TYW1,RAP1B,ABCF1,ATP9B,DYNC1H1,ASCC3,EPRS,NME7,NSF,TRAP1,FGFBP1,VCAN,CDK9,RIOK3,GPN1,DPEP1,MAP2K4,DNM3,MAP2K5,ABCA3,DDX18,PAFAH1B1,ATP6V1A,HFM1,KIAA0232,ACTR3,PDK4,OLA1,DDR2,MYH9,TUBB6,CBWD5,MCM9,HSPA1A,PDE3A,CHD7,NUBPL,FLAD1,PRKD3,ASNS,ABCA12,CLCN6,MSH4,CMPK1,PXK,CDK12,PMS1,RFC4,GARS,PDK1,MTIF2,LGALS1,GNL1,GALK2,STK10,MAT2A,FGFR1,DHX57,CAMK2D,HIPK2,DNAJA3,ARL13B,CBWD1,RPS6KB1,MDN1,NOLC1,RAB30,VWA8,FGFBP3,BRAF,SESTD1,C10orf2,FARS2,KIF5C,GAS6,IP6K2,MLH1,OPA1,RPS6KA5,DCTPP1,TTLL11,ABL1,CBWD6,GATC,HARS2,DYNC2H1,MAP3K14,ACTR3B,NAV3,CLK2,PFKFB4,FGF9,FBXO17,TTLL5,DDX24,BMS1,PTK2,PPIP5K2,OASL,UBE2K,GUF1,MMAA,DDX49,OXSR1,TRIB3,SRCAP,RARS,DDX50,HELZ,STX1A,ORC5,ATM,APAF1,BMP4,ADK,STK4,MVK,ATRX,RARS2,KIF5A,MFGE8,TRPM6,CSNK2A1,STK33,MAP2K3,SRPRB,ABL2,RAP1A,DHX33,TRMU,XRCC2,MYH3,POLR3B,PCOLCE2,RAN,SLC27A5,YARS,LONP1,TRIP13,PRKACB,SRPK2,TNK2,CHD9,ABCC4,SKIV2L2,HARS,KATNAL1,CDK4,HSPA5,KSR2,MTHFD1L,SGK2,LSG1,TIMM44,PEX1,KIF16B,RHOU,DYRK1B,HLCS,CHD3,ARL4A,EEFSEC,RAD51B,ABCC3,MAGI1,SEPHS2,XYLB,TTN,SARS,MCM6,AK2,FN1,CLK1,TAF1,RHOBTB1,DNAH1,ABCA5,PDE10A,GLTP,ALDH18A1,N4BP2,MTHFD1,WARS2,CAMKK2,LAMC1,PDE4A,BCS1L,OBSCN,LIG4,AGAP1,UBE2E1,DNAH14,ATAD5,DNAH17,IRAK2,HK2,RRAGA,DDX10,BRSK2,TBCK,PRKAR2A,SUCLG1,PAPD4,CEMIP,MYO7A,TNXB,SMARCA4,RIPK1,DHX35,DDX60L,MIEF1,RIOK2,CAD,FARSA,NVL,RPS6KL1,IKBKB,MYH15,MET,VCL,SKIV2L,NARS2,ACSL5,TUBA1A,DDX41,NARS,RAB7A,VIM,ATP8B2,EDEM2,ARL5B,RAB10,WARS,TPK1,RAD54B,ATP5D,SCARB1,SEPT5,SMG1,TNIK,BCKDK,MINK1,DNAJA4,MAP3K13,CAMK1,ARL15,PDE4B,TKFC,ARFIP2,APRT,VARS,CSNK1A1,PIP4K2A,MFHAS1,GFM2,PRKCH,GART,NDUFV1,DDX31,POLR1B,CD44,PCK2,HSD17B12,PCSK6,RPS6KB2,GPHN,FGF2,SMARCAD1,ABCF2,DHX34,TEX14,MARS,GPNMB,PDE2A,RHOT2,EIF5B,PEAK1,PIK3CB,TARS,ZRANB3,HSPA1B,MFN2,GPC2,MSH3,RPS6KC1,ZAK,KIF1B |
| 2.239e-05 | -10.71 | PUJANA_ATM_PCC_NETWORK | MSigDB lists | PUJANA_ATM_PCC_NETWORK | 1381 | 228 | 17758 | 2279 |
GNB3,ADAM19,MVK,PHF3,CUL4A,UBN1,CSNK2A1,GIT2,CIAPIN1,ZNF37A,SMARCB1,ZNF804A,AMPD3,RAP1A,SRSF2,ATP5G2,XRCC2,ANAPC10,UBAP2L,PDS5B,MYH3,WIZ,ME1,POLE3,RAN,B3GNTL1,KIAA0922,CEP135,FXN,OGG1,TMPO,NRAS,BAZ2A,KLHL23,CUX1,ATG12,BRCA1,PITPNB,MCM2,ODC1,DLST,MAK16,CHAF1A,ARPC3,DDX3X,SLC7A1,LSS,ZNF266,GATA6,LSM14A,E2F4,TECPR2,CRCP,XPNPEP1,PPP3CC,PRPF4,RUNX1,TNFRSF10D,BLMH,EP400,MCM6,PRPF31,TAF1,KHDRBS1,PAX2,SMG7,PARN,CLINT1,ZNF354A,SLC7A11,MCM5,ATIC,COPS3,MBD2,MYC,SEMA3D,TIMELESS,CTR9,ANP32B,PRPS1,PABPC1,SERBP1,SCAF11,KRT20,GTF2H3,DDX28,EXOSC2,RREB1,RB1CC1,POLA1,AOC2,TRA2A,RAP1B,TTYH2,USP10,ARID1A,CPT1A,ARIH2,UBE2E1,MTHFD2,SYNCRIP,GTF2A1,KIAA0355,SNAP23,RIOK3,ZNF160,HK2,GPN1,PEX13,KIAA0196,PTP4A2,DDX10,ZFHX2,RNF114,ZBTB24,KCTD7,ZNF516,DDX18,URB2,ACTR3,SLC2A1,KLHL18,RSL1D1,LPCAT3,ISG20L2,POP5,SSBP2,PIBF1,URB1,SEMA6A,PELP1,NOP56,CAD,CD96,RRN3,FMNL1,IKBKB,MYH15,SSBP1,CORO1A,PRMT3,CASP10,HTRA2,PRPF19,SAP30,KDM3B,RFC4,RFC3,PDK1,TFCP2,PARP2,NPM3,TMEM123,PNN,DKC1,NUP214,STK10,EIF3H,MAT2A,HTR7,TAF2,BAZ1A,RBBP8,HNRNPR,ADNP,ABHD3,CEBPZ,FTSJ1,ALKBH1,RPS6KB1,MED20,NOLC1,MAPT,RAB30,DNAJC2,NCOR2,INSIG2,XPC,TCF3,NFX1,LIAS,TRIM22,RNASEH2B,MBNL1,POM121,SFI1,PTPN2,ABL1,NPRL2,POLR3D,SNW1,NOP16,TANK,ACOT11,SHMT2,UPF2,CELF1,FBL,LARP4B,HNRNPM,TOP1,CLK2,PFKFB4,ERICH1,APEX1,KCNMA1,ABCF2,PSMC3IP,LDHA,ADSL,BMS1,EXOG,PPIP5K2,EIF5B,RPA1,POLR3G,OXSR1,TOE1,ZNF330,SET,ORC5,CUL2,ATM,NCBP2,IGBP1,MTMR1,RABEP1,STK4 |
| 2.400e-05 | -10.64 | organophosphate metabolic process | biological process | GO:0019637 | 814 | 146 | 16441 | 2138 |
PIGM,MVK,PRDX6,NT5C3A,COX10,ABHD6,SYNJ1,LPIN1,AMPD3,ATP5G2,MYH3,PPCDC,ME1,NDUFA6,FXN,OGG1,ITPA,UPP1,GPCPD1,PITPNB,DLST,STOML2,HPRT1,GATA6,XYLB,AK2,PIGN,AK6,GPAT3,PIK3R4,DPM3,PLA2G12A,NDUFS7,NAMPT,PI4KB,ENTPD5,ATIC,PDE10A,PIGG,SYNJ2,PNPLA3,LPCAT1,PRPS1,FDFT1,NT5E,MTHFD1,HMGCR,FADS1,BDNF,PDE4A,PPAT,IDH3G,IMPDH2,PLCB1,VAC14,PGD,CAT,NME7,FDPS,SURF1,TBPL1,HK2,UMPS,BPNT1,PDE9A,NDUFA5,SUCLG1,ATP6V1A,PAFAH1B1,LPCAT2,NTSR1,NDUFB5,PIGH,OLA1,LPCAT3,PUDP,LCLAT1,HSPA1A,PDE3A,NDUFB3,FLAD1,CAD,IDI1,LPIN2,NT5C,FHIT,CMPK1,MTHFD2L,MGLL,LYST,MCEE,GARS,PI4KAP2,DLG4,ATP6V0A1,NUDT15,TPK1,SNCA,ATP5D,PDE8B,TAMM41,DCXR,G6PD,PEMT,ABHD3,MUTYH,SMG1,SERINC5,SULT1C2,PDE4B,TKFC,CHCHD10,APRT,IP6K2,RNASEH2B,INPP1,PIP4K2A,DCTPP1,GART,NDUFV1,CPNE7,NT5M,PFKFB4,GPHN,FGF2,SMARCAD1,AGPAT4,LDHA,SULT4A1,ADSL,PPIP5K2,PDE2A,PDE3B,NAPEPLD,PIK3CB,SMPDL3B,HSPA1B,ALG5,SERINC1,COQ9,SRD5A3,ATM,NDUFS5,GPAM,MTMR1,ADK |
| 2.431e-05 | -10.62 | AAGCCAT,MIR-135A,MIR-135B | MSigDB lists | AAGCCAT,MIR-135A,MIR-135B | 318 | 67 | 17758 | 2279 |
BTBD2,RPS29,RNF43,ST7L,ZNF44,GABPB2,SKI,PRKD3,ZDHHC6,WAC,NCKIPSD,NBEA,JOSD1,PHLDB2,ZCCHC14,AEBP2,STAMBP,SFSWAP,SON,MAT2A,BSN,PDE8B,DDX3X,MSX2,KPNA3,KLF4,ZNF236,SOCS4,RPS6KB1,RUNX1,USP15,MEF2C,CADM4,FOXO1,B4GALT5,CENPB,IGF2BP2,CSNK1A1,BZW2,MAN1A1,MTUS1,FKBP1A,ANXA7,NDRG4,IGF2BP1,CALN1,DMRT1,DIS3L2,PDE4A,SYNGAP1,MON1A,FOXN3,ZBED4,USP42,IDH3G,ARID5B,KCNMA1,PTK2,PLCB1,EVI5,HIF1A,TAF4,ORC5,RNF138,ZRANB2,MBD6,LMBRD2 |
| 2.456e-05 | -10.61 | regulation of cardiac muscle cell action potential involved in regulation of contraction | biological process | GO:0098909 | 12 | 8 | 16441 | 2138 |
CAMK2D,DSC2,JUP,ANK2,DSG2,RYR2,CAV1,DSP |
| 2.504e-05 | -10.59 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP | 178 | 43 | 17758 | 2279 |
NDUFA5,SHQ1,TRERF1,TAF1,MRPL10,HLTF,IKBKAP,TGFBR2,UBR5,ETFB,MRPS11,RAP1A,MCAM,MRPS27,SOCS6,RNF2,AGL,TERF2,SAP30,MCEE,EXOSC2,FAM172A,ALG6,APEX1,PPAT,SKIV2L2,ANKMY2,AP4B1,TSN,LRRC8A,FOXRED1,FBXO21,KDM4B,ELP2,PALB2,AGTPBP1,MKL2,ORC5,SET,BIVM,ZFP90,PUS1,COPS6 |
| 2.524e-05 | -10.59 | EGFR (epidermal growth factor receptor) | protein interactions | 1956 | 835 | 160 | 16036 | 2270 |
AAMDC,MRPL10,CSNK2A1,TTI1,PRKCA,BIRC2,MAP2K3,TOM1L1,SRPRB,ABL2,CMSS1,THADA,ZFYVE28,AP1M1,YARS,LONP1,TIMM50,PTPRK,CDC37,TNK2,SLC3A2,LIMA1,ITPA,EXOC6B,HSPA5,AKAP12,CAV1,DDX60,MGST1,AHNAK,LRRC40,TNFRSF1A,SOCS4,MPV17,SGSM2,RIOK1,CLU,TPM1,JUP,FN1,HSD17B10,CCDC47,SSR4,XPO7,PHGDH,SLC39A11,SH2B3,PRKCE,ATXN2,ATIC,TNPO3,GEMIN4,MAP3K12,LRSAM1,CAV2,FDFT1,XPO5,UTP15,PTPN12,VAC14,NCDN,EXOC6,IRS1,DYNC1H1,APBB3,EPRS,NSF,FDPS,EXOC4,HK2,UMPS,MAP2K4,COG5,BCCIP,UROD,PPP2R2A,RIPK1,TUBB6,AP1B1,HSPA1A,GBF1,RIOK2,FARSA,ANKRD13A,ASNS,SHC1,SOCS1,CCDC50,ARMC6,SOCS6,ETF1,SSBP1,MET,PRMT3,IPO11,SKIV2L,RFC4,RFC3,PDK1,TUBA1A,KRT7,LGALS1,UBR4,DCBLD2,SNCA,DNAJA3,CEBPZ,H2AFX,ACP1,TRMT2A,PUS1,EIF2B3,AP2S1,ANKS1A,MAPT,SH2D3A,SCAMP3,TTC27,CMTM8,APRT,VARS,WDR26,MON2,IKBKAP,OPA1,CSNK1A1,BZW2,NEDD4,PTPN2,ABL1,PTRF,IFIT5,DSG2,LTN1,ARHGAP1,MAP3K14,CD44,ERRFI1,FBL,HSD17B12,FAM98A,PSPC1,ABCF2,TPM4,TBRG4,RAP1GDS1,MARS,RANGAP1,PTK2,PIK3CB,TARS,UBC,ANXA1,RPA1,OXSR1,RARS,TAF4,ORC5,XPO6,IPO4 |
| 2.529e-05 | -10.59 | ONKEN_UVEAL_MELANOMA_DN | MSigDB lists | ONKEN_UVEAL_MELANOMA_DN | 505 | 97 | 17758 | 2279 |
PTP4A1,LYRM4,ATP6V1A,NDUFB5,PBX1,RSL1D1,COBLL1,HLTF,SSBP2,ST3GAL6,ABHD6,SEMA6A,AHCYL2,LPIN1,TOM1L1,YLPM1,ATG3,RABGAP1L,WAC,NCKIPSD,ZNF148,PCOLCE2,PEG10,TSPAN14,ETV1,PRKACB,FAM184A,LAMA4,SOBP,NARS2,RAB7A,MINA,CAV1,MCM2,ZNF91,ERC1,LSG1,SERP1,SNCA,GNAI1,CXADR,PLIN2,DDX3X,SMARCC1,PRPF4,CCNB1IP1,BRCC3,BMI1,NMD3,ZNF532,ZMAT3,KLHL24,IFT57,TRIP6,XPC,LARS2,C10orf2,TRAK1,PDE4B,PIK3R4,ID2,FARS2,LETMD1,MBNL1,MTUS1,TOX4,ADH5,PRKCH,C6orf48,MCAM,DYNC2H1,MFAP2,FBL,GMDS,CD44,NRIP1,CAV2,SERBP1,NIPSNAP1,FDFT1,KDM5B,IL11RA,EIF4A2,SETD2,IMPDH2,PALLD,MBNL2,USP46,PGD,ATXN7,RPL28,SNAP23,RIOK3,SLC16A1,UMPS,PREPL,PTP4A2 |
| 2.534e-05 | -10.58 | MCPH1 (microcephalin 1) | protein interactions | 79648 | 27 | 13 | 16036 | 2270 |
BRCA2,SMARCC1,BIRC6,TP53BP1,H2AFX,ATM,SMARCA4,ABCC2,CRACR2A,MCM2,KDM1A,RPA1,SMARCB1 |
| 2.565e-05 | -10.57 | WD40 | smart domains | SM00320 | 267 | 61 | 9131 | 1249 |
DMXL2,WDR75,GNB3,PAFAH1B1,WDR74,WDR13,PLRG1,PIK3R4,PPP2R2A,WDR26,WDR37,NUP43,CORO6,NBEAL1,DENND3,NLE1,AMBRA1,PEX7,WDR27,NBEA,PAK1IP1,WDR60,CORO1A,UTP4,LYST,SEH1L,PRPF19,WDR36,FBXW4,MIOS,WDR61,WDFY3,TLE3,WDR18,UTP15,WDR25,WDHD1,MED16,NUP214,PWP1,GEMIN5,SEC31A,NOL10,ELP2,WDR5B,WDR35,HERC1,WDR73,TECPR2,BCAS3,TSSC1,WDR7,IFT140,PRPF4,TBL1X,APAF1,WDR33,WDR66,BRWD3,DCAF5,CORO2B |
| 2.565e-05 | -10.57 | V$MAX_01 | MSigDB lists | V$MAX_01 | 247 | 55 | 17758 | 2279 |
ATP6V1A,DYM,NFX1,ATF7IP,BCOR,TGFB2,RLF,TIMM10,FOXO3,UBR5,BMP6,DHX35,IQGAP2,FAM192A,RSPRY1,PRKCH,CAD,SLC38A5,GLYR1,VGF,ACAP3,SLC38A2,GTF2H1,SUCLG2,CEP63,IGF2BP1,ETV1,ZCCHC7,PRPS1,PABPC1,SERBP1,NUDC,TOP1,MTHFD1,ATF4,ANAPC13,MON1A,SIGMAR1,AKAP12,ODC1,CPT1A,NOP58,UBR4,MAT2A,BATF3,DDX3X,SYNCRIP,PER1,VPS37B,CTAGE5,BCAS3,PFDN2,EME1,NIT1,USP15 |
| 2.566e-05 | -10.57 | DOC | prosite domains | PS51284 | 7 | 6 | 11866 | 1504 |
HERC2,MYCBP2,CUL7,ZZEF1,ANAPC10,HECTD3 |
| 2.567e-05 | -10.57 | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | 156 | 39 | 17758 | 2279 |
SLC12A7,EFNB2,CHST11,CYLD,ID1,FOXO1,TTC27,TNFRSF21,ID2,FOSL2,TGFB2,BIRC2,MFHAS1,PCDH7,NAMPT,PMAIP1,TANK,CD44,KDM6B,BDNF,SSFA2,IFNGR2,LAMC1,WWC1,MCL1,KLF6,TCF7L2,HERPUD1,DKK1,SNCA,PDE8B,VDR,BAZ1A,SLC39A14,IRS1,SMAD3,INSIG1,SEMA3C,NR2F2 |
| 2.570e-05 | -10.57 | biliary_tract-gallbladder-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-adenocarcinoma | 2936 | 445 | 17775 | 2278 |
ZNF292,MYCBP2,WDR74,CACNA1H,SBF2,CSPP1,SLC6A8,UBR5,LPIN1,MGA,AMBRA1,GIPR,EXOC1,ZFHX3,SYN2,RABGAP1L,RNF111,ME1,KDM5C,MEIS3,FTSJ3,SEH1L,CSGALNACT2,NRAS,KLHL23,ATG9A,EHMT1,CUX1,AKAP12,ABCC2,PLCXD2,SPOP,AHNAK,BRCA2,TRRAP,LRRC40,VPS13D,RUNX1,NRP1,SLC25A26,PTPN14,HERC2,PRPF38B,EP400,CELSR1,CCDC53,TRIO,NHS,RSF1,TGFBR2,CDC73,CD226,SLC39A11,MTUS1,FKBP1A,DHX37,KIAA1671,INTS7,ASAP1,MYC,ZNF326,GTF3C3,LPCAT1,AGL,PABPC1,GATAD2B,SCAF11,COL17A1,RREB1,KCNQ3,ZNF587,PRDM16,ARID5B,RAPGEF4,TYW1,EPS15L1,KIAA0586,PTPN12,ST6GALNAC3,IMPDH2,SNAP25,ARID1A,TRIM37,MBNL2,EHBP1,MTR,ATP9B,DAGLA,DYNC1H1,CAT,EPRS,ASCC3,VPS13C,TSR1,LRP1B,TASP1,KPNA1,GSTO2,CLASRP,SPEN,ZZEF1,D2HGDH,SURF1,RIOK3,KIAA0196,NCOR1,WDR33,IQSEC2,DHCR7,PDLIM5,MAP2K4,COG5,RTTN,AMOTL1,TRPM2,BIRC6,DDX18,VTI1A,AGAP6,FAM122B,PTPRG,AP1B1,STAM,PDE3A,NOP56,CHD7,CD96,SLX4,KDM2A,SETD5,FMNL1,VGF,WAC,CLCN6,NBEA,TTC3,GSTA4,KMT2A,CDK12,CASP8AP2,PMS1,KMT2D,PI4KAP2,MTIF2,WDPCP,ATP6V0A1,SATB2,MARCH6,MEGF11,TBC1D16,FGFR1,HTR7,TAF2,ARHGAP21,ELP2,G6PD,METTL6,LARGE,HOXA3,IFT140,RPS6KB1,MDN1,KLHDC4,SETD6,LAMA5,METTL2B,YEATS2,CATSPERG,LRCH1,MORC2,SSH2,BRAF,TTC27,XPC,XRRA1,TCF3,FARS2,WDR37,ATG2B,IP6K2,MLH1,OPA1,IKBKAP,GIGYF2,FOXO3,POM121,KRI1,ABL1,TAF3,NOP16,PVRL3,UNC13A,ACTR3B,C15orf41,DIS3L2,CLK2,PFKFB4,FER1L5,FAM98A,TTLL5,DDX24,FZD3,NXN,PACS1,BMS1,RSBN1,PDE3B,KLF6,GUF1,ZFP62,OXSR1,RARS,RETSAT,NSD1,BAZ2B,PXDN,HELZ,ARID3B,HERC1,HNRNPH3,ATM,SVIL,APAF1,BRWD3,DOCK6,LRRC41,IMMP2L,CUL7,ATRX,NF1,KIF5A,POLR1A,FANCD2,TRPM6,SLC25A21,CSNK2A1,RNF43,BCOR,FAM13A,TMEM132A,SNAPC4,SLC30A7,SMARCB1,ZNF804A,PHF5A,ARHGAP18,LONRF2,ATG3,TRMU,NCKIPSD,ANKRD11,HKR1,MYH3,TRIML2,ZEB1,HYAL1,POLR3B,SLC35C2,VPS13B,TIMM50,LAMA4,ZBTB17,FLNC,CHD9,ABCC4,CMIP,PPARG,ANK2,CDK4,GDPD1,KSR2,LAMA2,CAV1,BRCA1,SGK2,KMT2C,DLST,CRYBG3,PEX1,YTHDF2,CHAF1A,TMEM132B,TCF7L1,SUFU,TECPR2,CCDC146,MKL2,CSMD3,CLU,COPS6,RNF214,DCAF5,SLC12A7,CLK1,TAF1,C16orf52,PRSS3,MAPK8IP3,MED13L,TRIM15,ZFP36L1,QSER1,ARID1B,RNF40,KIAA1958,RNFT2,SIPA1L3,ABCA5,CEP290,PDE10A,PRF1,CWF19L2,LRP3,AKAP11,N4BP2,KRT20,CAMKK2,LAMC1,IFT43,XPO5,ELP3,SETD2,UTP15,WBSCR22,OBSCN,CORIN,AGAP1,TCF7L2,VAC14,EXOC6,TBC1D2,PWP1,APBB3,FAM135A,PALB2,KIAA0355,FSCN1,INTS5,FAT1,KIAA0754,SNX24,CASS4,TBL1X,TBCK,PDE9A,CHMP2A,ASH1L,CYLD,PCNT,ARID2,LPCAT2,MYO7A,SMARCA4,TMEM177,ZNF83,DENND3,TNKS1BP1,SEMA6A,DDX60L,DHX35,PLXNB1,ZSCAN5A,ZC3H13,FARSA,NVL,UBR1,RNF2,ANO8,MET,ITGAX,TMLHE,NARS2,ANTXR2,EVL,COL5A2,SSFA2,NARS,KIRREL2,R3HDM1,VIM,AKAP13,NHSL1,NUP214,BTBD11,EXO1,ARMC4,RANBP2,SIX5,ATG7,TMEM101,NFASC,PUS1,EIF2B3,BRD9,ZNF589,MUTYH,SMG1,PARD3,TNIK,MAP3K13,SUPT6H,RFX1,MAP1S,IGF2BP2,MFHAS1,FAM49A,CPNE7,CD44,LDLRAD3,FBL,RPS6KB2,KDM6B,ADAMTSL3,PSPC1,ZMYM5,PPP1R21,C22orf34,SULT4A1,ASAP3,ARHGEF12,PDE2A,MEN1,GPNMB,PALLD,RHOT2,ZNF407,EIF5B,CHCHD6,TMEM175,PIK3CB,ARMC3,RERE,CENPP,TPD52L2,ALG5,NOL10,DAGLB,GPC2,SRBD1,TAF4,TBX3,EIF2S1,TAF12,ZAK,GCSH |
| 2.570e-05 | -10.57 | gallbladder | COSMIC cancer mutations | gallbladder | 2936 | 445 | 17775 | 2278 |
ZNF292,MYCBP2,WDR74,CACNA1H,SBF2,CSPP1,SLC6A8,UBR5,LPIN1,MGA,AMBRA1,GIPR,EXOC1,ZFHX3,SYN2,RABGAP1L,RNF111,ME1,KDM5C,MEIS3,FTSJ3,SEH1L,CSGALNACT2,NRAS,KLHL23,ATG9A,EHMT1,CUX1,AKAP12,ABCC2,PLCXD2,SPOP,AHNAK,BRCA2,TRRAP,LRRC40,VPS13D,RUNX1,NRP1,SLC25A26,PTPN14,HERC2,PRPF38B,EP400,CELSR1,CCDC53,TRIO,NHS,RSF1,TGFBR2,CDC73,CD226,SLC39A11,MTUS1,FKBP1A,DHX37,KIAA1671,INTS7,ASAP1,MYC,ZNF326,GTF3C3,LPCAT1,AGL,PABPC1,GATAD2B,SCAF11,COL17A1,RREB1,KCNQ3,ZNF587,PRDM16,ARID5B,RAPGEF4,TYW1,EPS15L1,KIAA0586,PTPN12,ST6GALNAC3,IMPDH2,SNAP25,ARID1A,TRIM37,MBNL2,EHBP1,MTR,ATP9B,DAGLA,DYNC1H1,CAT,EPRS,ASCC3,VPS13C,TSR1,LRP1B,TASP1,KPNA1,GSTO2,CLASRP,SPEN,ZZEF1,D2HGDH,SURF1,RIOK3,KIAA0196,NCOR1,WDR33,IQSEC2,DHCR7,PDLIM5,MAP2K4,COG5,RTTN,AMOTL1,TRPM2,BIRC6,DDX18,VTI1A,AGAP6,FAM122B,PTPRG,AP1B1,STAM,PDE3A,NOP56,CHD7,CD96,SLX4,KDM2A,SETD5,FMNL1,VGF,WAC,CLCN6,NBEA,TTC3,GSTA4,KMT2A,CDK12,CASP8AP2,PMS1,KMT2D,PI4KAP2,MTIF2,WDPCP,ATP6V0A1,SATB2,MARCH6,MEGF11,TBC1D16,FGFR1,HTR7,TAF2,ARHGAP21,ELP2,G6PD,METTL6,LARGE,HOXA3,IFT140,RPS6KB1,MDN1,KLHDC4,SETD6,LAMA5,METTL2B,YEATS2,CATSPERG,LRCH1,MORC2,SSH2,BRAF,TTC27,XPC,XRRA1,TCF3,FARS2,WDR37,ATG2B,IP6K2,MLH1,OPA1,IKBKAP,GIGYF2,FOXO3,POM121,KRI1,ABL1,TAF3,NOP16,PVRL3,UNC13A,ACTR3B,C15orf41,DIS3L2,CLK2,PFKFB4,FER1L5,FAM98A,TTLL5,DDX24,FZD3,NXN,PACS1,BMS1,RSBN1,PDE3B,KLF6,GUF1,ZFP62,OXSR1,RARS,RETSAT,NSD1,BAZ2B,PXDN,HELZ,ARID3B,HERC1,HNRNPH3,ATM,SVIL,APAF1,BRWD3,DOCK6,LRRC41,IMMP2L,CUL7,ATRX,NF1,KIF5A,POLR1A,FANCD2,TRPM6,SLC25A21,CSNK2A1,RNF43,BCOR,FAM13A,TMEM132A,SNAPC4,SLC30A7,SMARCB1,ZNF804A,PHF5A,ARHGAP18,LONRF2,ATG3,TRMU,NCKIPSD,ANKRD11,HKR1,MYH3,TRIML2,ZEB1,HYAL1,POLR3B,SLC35C2,VPS13B,TIMM50,LAMA4,ZBTB17,FLNC,CHD9,ABCC4,CMIP,PPARG,ANK2,CDK4,GDPD1,KSR2,LAMA2,CAV1,BRCA1,SGK2,KMT2C,DLST,CRYBG3,PEX1,YTHDF2,CHAF1A,TMEM132B,TCF7L1,SUFU,TECPR2,CCDC146,MKL2,CSMD3,CLU,COPS6,RNF214,DCAF5,SLC12A7,CLK1,TAF1,C16orf52,PRSS3,MAPK8IP3,MED13L,TRIM15,ZFP36L1,QSER1,ARID1B,RNF40,KIAA1958,RNFT2,SIPA1L3,ABCA5,CEP290,PDE10A,PRF1,CWF19L2,LRP3,AKAP11,N4BP2,KRT20,CAMKK2,LAMC1,IFT43,XPO5,ELP3,SETD2,UTP15,WBSCR22,OBSCN,CORIN,AGAP1,TCF7L2,VAC14,EXOC6,TBC1D2,PWP1,APBB3,FAM135A,PALB2,KIAA0355,FSCN1,INTS5,FAT1,KIAA0754,SNX24,CASS4,TBL1X,TBCK,PDE9A,CHMP2A,ASH1L,CYLD,PCNT,ARID2,LPCAT2,MYO7A,SMARCA4,TMEM177,ZNF83,DENND3,TNKS1BP1,SEMA6A,DDX60L,DHX35,PLXNB1,ZSCAN5A,ZC3H13,FARSA,NVL,UBR1,RNF2,ANO8,MET,ITGAX,TMLHE,NARS2,ANTXR2,EVL,COL5A2,SSFA2,NARS,KIRREL2,R3HDM1,VIM,AKAP13,NHSL1,NUP214,BTBD11,EXO1,ARMC4,RANBP2,SIX5,ATG7,TMEM101,NFASC,PUS1,EIF2B3,BRD9,ZNF589,MUTYH,SMG1,PARD3,TNIK,MAP3K13,SUPT6H,RFX1,MAP1S,IGF2BP2,MFHAS1,FAM49A,CPNE7,CD44,LDLRAD3,FBL,RPS6KB2,KDM6B,ADAMTSL3,PSPC1,ZMYM5,PPP1R21,C22orf34,SULT4A1,ASAP3,ARHGEF12,PDE2A,MEN1,GPNMB,PALLD,RHOT2,ZNF407,EIF5B,CHCHD6,TMEM175,PIK3CB,ARMC3,RERE,CENPP,TPD52L2,ALG5,NOL10,DAGLB,GPC2,SRBD1,TAF4,TBX3,EIF2S1,TAF12,ZAK,GCSH |
| 2.605e-05 | -10.56 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | 499 | 96 | 17758 | 2279 |
TBKBP1,UPK3B,DDX18,BTBD2,ATRX,RBFOX2,ENAH,ISG20L2,PTPRG,SAFB2,METTL16,CAD,SHC1,ZKSCAN1,GLYR1,SLC38A2,MMP14,RNF2,ZNF148,POLE3,VCL,PRPF19,SKIV2L,ZCCHC14,DPF3,NRAS,COL5A2,FAM172A,STAMBP,SFSWAP,RAB7A,COL4A3BP,KIF15,MED16,PITPNB,SOX4,RBM28,SON,ST3GAL5,RAB10,MLLT10,SMAD3,GNG2,GATA6,KPNA3,ACP1,RPS6KB1,NRP1,NOLC1,TROVE2,LPP,TMEM33,SLC12A7,EPM2AIP1,PRPF38B,PPHLN1,ATF7IP,WDR26,FOXP1,SNW1,ATXN2,ATIC,PMPCA,TNPO3,CELF1,PKNOX1,MYB,HMGCR,TSHZ1,BDNF,POLA1,ABCF2,UTP15,TPM4,FERMT2,RANGAP1,MAPK1IP1L,MEN1,EIF5B,MBNL2,ABCF1,TCF7L2,NR2F1,EPRS,UBAP2,GPC2,INTS5,HNRNPH3,LEMD3,ZBTB12,TBX3,UMPS,TBL1X,PSAP,KIF1B,PRKAR2A |
| 2.617e-05 | -10.55 | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP | MSigDB lists | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP | 78 | 24 | 17758 | 2279 |
DDX28,WDR74,EIF3J,MINA,RCHY1,PSMG1,SLC29A1,NUP214,ODC1,CUTC,GLS,PWP1,VPS13C,SPG21,TMEM161A,TRIAP1,ZNF460,PDCD11,NOLC1,BLMH,DHCR7,XPO6,GCSH,PRPF19 |
| 2.622e-05 | -10.55 | negative regulation of metabolic process | biological process | GO:0009892 | 2618 | 406 | 16441 | 2138 |
MYCBP2,CHAC1,PRKCA,NUP160,UBR5,SKI,SREBF2,ZFHX3,ZFYVE28,MAD1L1,ZNF148,FNIP2,KDM5C,HRG,ZNRD1,SEH1L,HMBOX1,NR6A1,EHMT1,NFIA,CUX1,SAP30BP,SPOP,DOT1L,GZF1,DDX3X,SKIL,BRCA2,SUPT4H1,RAD18,CCNT1,SH3RF1,HIC2,TNFRSF10D,BMI1,SPOCK3,MEF2C,BANP,DROSHA,EGR1,ZHX3,KHDRBS1,SIRT7,OPHN1,PID1,RSF1,PDCD5,CDC73,ABCA7,IGF2BP3,FKBP1A,CNST,HR,MYC,IGF2BP1,PRMT5,LPCAT1,PABPC1,TERF2,MYB,HMGCR,ADARB1,ZNF675,GATAD2B,GTF2H3,RREB1,PRDM16,ARID5B,EIF4A2,ARID1A,NELFA,PLCB1,TRIM37,ANGPTL4,ZNF425,CAT,EPRS,EHMT2,TRAP1,PMEPA1,HIF1A,CDK9,SPEN,CCDC85B,PURB,DPEP1,CNOT6,NCOR1,SMYD3,ZNF254,SPRED2,MAP2K5,BIRC6,LIN28B,PAFAH1B1,NUP43,HSPA1A,RING1,PAIP2,TERF2IP,ACD,ERI1,PPID,UCHL5,WAC,SOCS6,SERPINH1,PXK,CASP8AP2,SAP30,KMT2D,DLG4,SATB2,FGFR1,PDE8B,SNCA,VDR,MSX2,CDC16,SMARCC1,ELP2,DNAJA3,HIPK2,G6PD,H2AFX,TRAF3,ANXA2,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,SHQ1,INSIG2,TCF3,NFX1,ID2,GAS6,AKT1S1,TRIM22,MLH1,BHLHE40,NOL3,TGFB2,RNASEH2B,RPS6KA5,GIGYF2,FOXO3,PSMF1,MAD2L2,NEDD4,POM121,ABL1,SNW1,NPRL2,SUV39H2,TAF3,TRIAP1,ANXA5,RDX,CELF1,YBX3,ERRFI1,SAMD4A,SOX6,CLK2,FGF9,APEX1,ZFYVE1,NXN,IL6R,PDE3B,UBC,POLR2A,ANXA1,TRIB3,KLHL22,NSD1,IREB2,HERC1,ATM,BMP4,IGBP1,ANAPC4,DDIT3,KAT6A,UBN1,ATRX,NF1,PPARGC1B,POLR1A,CSNK2A1,BCOR,SIRT2,NLE1,BIRC2,SMARCB1,ANAPC1,ECM1,SRSF2,YLPM1,JAZF1,GPR87,ANAPC11,ANAPC10,RELB,ZEB1,ZNF85,RAN,SLC35C2,HCFC2,OGG1,TRIM14,PTPRK,DEAF1,TNK2,TRIM13,RBCK1,ATF4,AEBP2,SIRT6,PPARG,BAZ2A,TFPI,ARRDC3,TSN,MINA,GMFB,HDAC8,BRCA1,CAV1,SOX4,ZNF91,TAF9B,UBTF,PAF1,TCF7L1,EIF4ENIF1,GATA6,SUFU,INSIG1,DNAJC1,CC2D1B,PER1,SOCS4,CLU,DLX2,ZC3H8,BEND6,NOCT,TNRC6A,FOXO1,PAX2,UBXN1,SMAD7,HES6,BARX2,ZIC2,DDIT4,RNF40,ELL,P3H1,MLX,MBD2,ATXN2,VPS72,SAMD11,GTF2H1,CTR9,TIMELESS,NRIP1,POLR1E,PAXBP1,XPO5,WWC1,PSMA1,RNH1,PRDM1,SUPT5H,HERPUD1,ISG15,UBE2E1,TCF7L2,NR2F1,ATXN7,BICD1,MYBBP1A,SYNCRIP,IRAK2,HK2,RRAGA,PTRH2,ZFP90,TBL1X,PRKAR2A,TESC,AGO3,N4BP2L2,USP7,ZNF706,DLL4,ID1,ASH1L,CYLD,FEZ2,UPK3B,RBFOX2,SMARCA4,PBX1,RIPK1,CSTA,PIBF1,KDM1A,ZBTB21,MPHOSPH10,SOCS1,GRIN2C,NUP133,DNAJB6,IKBKB,RNF2,FHIT,MET,PRMT3,CTC1,MOSPD1,TMLHE,KAT8,PRAME,PTBP2,KIRREL2,SFSWAP,POU2F1,ATXN1,ENC1,NUP214,BATF3,ZC3H12A,SMAD3,RANBP2,RBBP8,IKZF4,ADNP,SIX5,KLF4,ARNTL,ATG7,DUSP19,EIF2B3,PKIB,PARD3,DNAJC2,NIFK,SUPT6H,AGO2,H2AFJ,IGF2BP2,ATF7IP,CHCHD10,PPP1R1C,SOGA1,FOXP1,BMP6,HIST2H2AB,SFI1,IQGAP2,PTPN2,ANXA7,STC2,HIST2H3D,POLR1B,FBXO31,CD44,AMOT,DMRT1,PPP1R9B,MSX1,KDM5B,CRIM1,PSPC1,FOXN3,KDM5A,DHX34,TEX14,SCMH1,PHACTR2,HIST1H4J,PDE2A,MEN1,ZRANB3,RERE,HSPA1B,DKK1,MKX,GADD45A,TBX3,SET,MSH3,BCAS3,GLG1,EIF2S1,NCBP2,RBM26,RBPJ,POLR1C,NR2F2 |
| 2.626e-05 | -10.55 | ZF_PHD_1 | prosite domains | PS01359 | 79 | 24 | 11866 | 1504 |
DPF3,KMT2D,ASH1L,PHF3,KDM5B,KMT2E,KDM5A,DPF2,NFX1,RSF1,KMT2C,CHD5,TRIM66,MLLT10,BAZ1A,NSD1,KDM2A,TAF3,CHD3,INTS12,KDM5C,FBXL19,KMT2A,KAT6A |
| 2.668e-05 | -10.53 | V$USF_C | MSigDB lists | V$USF_C | 265 | 58 | 17758 | 2279 |
CGN,CHST11,SPATA2L,TNFRSF21,PPARGC1B,ST6GAL1,UBXN1,NAT10,RNF43,GYG1,BHLHE40,TIMM10,PABPC4,PRKCE,VGF,ACAP3,SLC39A7,GTF2H1,SUCLG2,IGF2BP1,FBL,ETV1,CNOT4,PABPC1,SERBP1,NUDC,MTHFD1,EXOSC2,PPP1R9B,TXLNG,SIGMAR1,PPAT,EIF3J,ARRDC3,SCFD2,NLN,AKAP12,SATB2,SLC9A5,MAT2A,HERPUD1,BATF3,CTIF,GTF2A1,ADNP,PER1,HSPBAP1,SET,POLR3E,BCAS3,HOXA3,AEN,BMP4,PFDN2,GCSH,IPO4,ATXN7L2,KAT6A |
| 2.713e-05 | -10.52 | JOHNSTONE_PARVB_TARGETS_2_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_DN | 313 | 66 | 17758 | 2279 |
MYCBP2,TRERF1,TNFRSF21,RBFOX2,RCHY1,PPIL1,SSBP2,PTPRG,PRKCA,UBTD2,DST,ZFYVE28,UCHL5,PAK1IP1,CHD2,TMEM14C,CDK6,TMPO,GCNT2,ARRDC3,ARHGEF10,MSRB3,GLS,TAF2,DDAH2,CAMK2D,HNRNPR,CBWD1,RIOK1,TSPAN5,TROVE2,ZNF532,TMEM33,EPM2AIP1,AK2,PRPF31,SLK,SESTD1,NFX1,PRPF39,OPA1,CSNK1A1,MBNL1,C6orf48,UBE3A,PVRL3,GMDS,IFRD1,RREB1,PRIM2,STAG1,MRPS10,RAP1GDS1,PTK2,EHBP1,C8orf33,USP46,IRS1,GTF2A1,SYNCRIP,AGTPBP1,LEMD3,RBM26,RBPJ,PTP4A2,POLR1C |
| 2.717e-05 | -10.51 | SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1) | protein interactions | 56916 | 123 | 35 | 16036 | 2270 |
USP7,ARID2,KHDRBS1,DDX19A,CSNK2A1,SMARCA4,PELP1,KDM1A,RING1,SMARCB1,ANAPC1,WIZ,GTF3C3,CPSF3,ZNF460,POLR1E,HNRNPM,PRPF19,TMPO,RFC4,RFC3,EHMT1,ZC3H18,WDR18,SYMPK,DDX3X,BAZ1A,CDC16,EHMT2,SMARCC1,HNRNPR,MSH3,MDN1,WDR33,NR2F2 |
| 2.723e-05 | -10.51 | APC_su10/DOC_dom | interpro domains | IPR004939 | 7 | 6 | 18293 | 2341 |
HERC2,MYCBP2,CUL7,ZZEF1,ANAPC10,HECTD3 |
| 2.723e-05 | -10.51 | Znf_FYVE_PHD | interpro domains | IPR011011 | 135 | 35 | 18293 | 2341 |
ASH1L,PHF3,ATRX,KMT2E,DPF2,RSF1,CHD5,EEA1,TRIM66,SPIRE1,KDM2A,ZFYVE28,TAF3,INTS12,KDM5C,KMT2A,FBXL19,DPF3,KMT2D,KDM5B,BAZ2A,WDFY3,ZFYVE1,KDM5A,KMT2C,MLLT10,BSN,BAZ1A,NSD1,BAZ2B,RBSN,KDM4B,CHD3,KDM4C,KAT6A |
| 2.735e-05 | -10.51 | spliceosomal complex | cellular component | GO:0005681 | 169 | 41 | 17570 | 2233 |
PRPF38B,SART1,ZCCHC8,PRPF31,TFIP11,PLRG1,SF3A3,PPIL1,PDCD7,PRPF39,DHX35,HNRNPA3,SCAF8,SNW1,SRSF2,BCAS2,PHF5A,CTNNBL1,CWC27,WAC,BUD31,ZNF326,GPATCH1,SRRM2,PABPC1,HNRNPM,PRPF19,SF3A1,SNU13,DDX41,PTBP2,SKIV2L2,PNN,RBM28,PRPF40B,SYNCRIP,HNRNPR,HNRNPH3,LUC7L3,PRPF4,PPIL3 |
| 2.830e-05 | -10.47 | TARDBP (TAR DNA binding protein) | protein interactions | 23435 | 291 | 67 | 16036 | 2270 |
SART1,CUL7,EIF3C,MYH9,HNRNPA3,PABPC4,FLNB,NOP56,SRPRB,RPS16,DNAJB6,MRPS27,RNF2,AHCYL1,SLC25A23,TRIP13,PRPF19,RFC4,SKIV2L2,GNL3,CDK4,HSPA5,GMFB,BRCA1,DSP,EIF3H,DHX57,YTHDF2,DDX3X,AHNAK,HNRNPR,XPNPEP1,FUS,BMI1,FN1,JUP,AGO2,HSD17B10,IGF2BP2,ZNF346,PHGDH,GIGYF2,NOP16,ATIC,ATXN2,CELF1,YBX3,FBL,PABPC1,HNRNPM,SERBP1,TOP1,MSI2,FAM98A,LSM12,USP10,NOP58,RPA1,TSR1,MYBBP1A,DDX50,HELZ,RPL28,SYNCRIP,SRBD1,IRAK2,PURB |
| 2.834e-05 | -10.47 | WDR5 (WD repeat domain 5) | protein interactions | 11091 | 143 | 39 | 16036 | 2270 |
CUL4A,PAFAH1B1,WDR26,NLE1,MGA,RING1,TERF2IP,TADA3,KANSL1,RNF2,PRMT5,KMT2A,HCFC2,CARM1,SERBP1,TERF2,MYB,SRPK2,KDM6B,KAT8,KMT2D,SESN2,WDR61,SETD1B,HARS,KMT2C,MEN1,UBC,RERE,MYBBP1A,WDR5B,KDM4B,COPS5,ARNTL,SENP3,TRAF3,BMI1,YEATS2,KAT6A |
| 2.944e-05 | -10.43 | double-strand break repair | biological process | GO:0006302 | 205 | 48 | 16441 | 2138 |
HERC2,FAN1,MLH1,RMI1,MCM9,MAD2L2,SFR1,ABL1,BRE,SLX4,KDM2A,ZSWIM7,APLF,XRCC2,ATRIP,TIMELESS,SPIDR,TRIP13,PRPF19,RFC4,RFC3,SIRT6,POLA1,SMARCAD1,EYA3,TOP3A,LIG4,APTX,HIST1H4J,BRCA1,UBC,RAD54B,RPA1,EXO1,RBBP8,BRCA2,PALB2,KDM4B,TP53BP1,NSMCE2,NSMCE1,H2AFX,RAD51B,ATM,EME1,BRCC3,XRCC4,SMG1 |
| 2.946e-05 | -10.43 | ATPase activity | molecular function | GO:0016887 | 422 | 85 | 16491 | 2164 |
ABCA3,ATP6V1A,DDX18,ATRX,KIF5A,DDX19A,MYO7A,OLA1,MYH9,SMARCA4,HLTF,HSPA1A,DHX35,ABCA12,LONRF2,DHX33,XRCC2,MYH3,CHD2,MSH4,ATP6AP1L,LONP1,SKIV2L,RFC4,PMS1,RFC3,DDX41,ABCC4,KATNAL1,HSPA5,KIF15,ATP6V0A1,ABCC2,ATP8B2,DHX57,RAD54B,ATP5D,PEX1,KIF16B,DDX3X,RAD18,CHD3,RAD51B,ABCC3,DNAH2,MDN1,CLU,VWA8,MCM6,AK6,KIF5C,ATF7IP,MLH1,RSF1,CHD5,DNAH1,ABCA7,DDX56,DHX37,ABCA5,GTF2H1,DDX31,DYNC2H1,ATP6V0D1,TOP1,DDX28,GTF2H3,DDX24,MYO10,ABCF2,EIF4A2,DHX34,ABCF1,DDX49,HSPA1B,ATP9B,ANXA1,DYNC1H1,ASCC3,DDX50,NSF,DNAH17,MSH3,DDX10,KIF1B |
| 2.957e-05 | -10.43 | negative regulation of nitrogen compound metabolic process | biological process | GO:0051172 | 1487 | 245 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,PRKCA,UBR5,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,GPR87,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,OGG1,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,ATF4,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,BRCA2,SUPT4H1,EIF4ENIF1,RAD18,SUFU,GATA6,CCNT1,CC2D1B,PER1,HIC2,CLU,DLX2,ZC3H8,BEND6,BMI1,TNRC6A,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,PID1,BARX2,ZIC2,RSF1,CDC73,ABCA7,IGF2BP3,DDIT4,RNF40,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,IGF2BP1,PRMT5,NRIP1,LPCAT1,PABPC1,TERF2,MYB,ZNF675,GATAD2B,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,EPRS,MYBBP1A,SYNCRIP,EHMT2,CDK9,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,AGO3,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,MAP2K5,CYLD,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,PAIP2,TERF2IP,ZBTB21,ACD,PPID,DNAJB6,RNF2,CTC1,CASP8AP2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,PTBP2,SFSWAP,ATXN1,POU2F1,SATB2,ENC1,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,EIF2B3,SETD6,YEATS2,HMGA2,DNAJC2,NOSTRIN,NCOR2,SHQ1,TCF3,AGO2,H2AFJ,NFX1,ID2,ATF7IP,IGF2BP2,GAS6,TRIM22,MLH1,BHLHE40,RPS6KA5,FOXP1,GIGYF2,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,CELF1,YBX3,SAMD4A,DMRT1,SOX6,FGF9,MSX1,KDM5B,APEX1,PSPC1,FOXN3,DHX34,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,ZRANB3,RERE,MKX,DKK1,TRIB3,NSD1,IREB2,SET,TBX3,MSH3,EIF2S1,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 2.971e-05 | -10.42 | TTTGTAG,MIR-520D | MSigDB lists | TTTGTAG,MIR-520D | 326 | 68 | 17758 | 2279 |
PTP4A1,HFM1,SBF2,ENAH,SPATS2L,UBR5,JAZF1,NBEA,ZMYM2,SEH1L,CASP8AP2,ELOF1,TMEM200A,TMPO,PCGF3,GPM6A,ATF4,CUX1,ATXN1,GNL1,ODC1,SON,CLNS1A,MLLT10,HTR7,RANBP2,ARL4A,LUC7L3,ABHD3,RPS6KB1,TXN2,BMI1,MEF2C,LPP,PRPF38B,RFX1,SESTD1,PRPF39,IGF2BP3,PTPN2,FKBP1A,UBE3A,NEBL,ATXN2,RDX,HNRNPM,NAV3,TSHZ1,WDR61,TEAD1,FOXN3,XPO5,JMJD1C,KCNMA1,RSBN1,MEX3B,PRDM1,SNAP25,SYT1,MBNL2,PHF6,TCF7L2,BAZ2B,GADD45A,BIVM,PURB,FNBP1L,STK4 |
| 3.005e-05 | -10.41 | MMS19 (MMS19 homolog, cytosolic iron-sulfur assembly component) | protein interactions | 64210 | 179 | 46 | 16036 | 2270 |
USP7,CTU2,DPH1,MON2,MLH1,IKBKAP,PDE3A,MTUS1,DST,BRE,EIF2S2,USPL1,ELP5,FMNL1,MYC,GTF2H1,LTN1,RNF2,LARP4B,FMNL2,TRIP13,HSD17B12,WDR36,PMS1,FMNL3,SLC3A2,PRIM2,PPAT,POLA1,XPO5,ELP3,TYW1,RANGAP1,EIF5B,MAK16,ABCF1,FBXL5,RANBP2,KPNA3,ELP2,EIF2S1,CDKAL1,TRMT2A,SLC25A11,DHCR7,MUTYH |
| 3.011e-05 | -10.41 | ANAPC10 | pfam domains | PF03256 | 7 | 6 | 16629 | 2165 |
HERC2,MYCBP2,CUL7,ZZEF1,ANAPC10,HECTD3 |
| 3.024e-05 | -10.41 | Cajal body | cellular component | GO:0015030 | 51 | 18 | 17570 | 2233 |
SART1,SHQ1,PRPF31,AK6,TRIM22,DKC1,LSG1,NOP58,ELL,TOE1,USPL1,PRPF4,ICE2,FBL,ZC3H8,NOLC1,SRRM2,LSM10 |
| 3.049e-05 | -10.40 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN | 185 | 44 | 17758 | 2279 |
SRM,MCM6,C17orf80,DYM,HSD17B10,CSNK2A1,TBCCD1,SLC29A1,NLE1,UBL5,ETFB,PUS3,ARMC6,MCM5,BANF1,PPCDC,B3GNTL1,PKNOX1,FAM98A,WDR36,EIF3J,TMEM126B,ATOX1,TPRA1,PEAK1,RBM28,C19orf70,PAF1,SLC7A1,GLS,HPRT1,TRIB3,MTHFD2,TRAP1,DNAJA3,ACOX1,ZNF557,PEMT,ORC5,PTRH2,FNTB,METTL2B,ANKS1A,GALE |
| 3.055e-05 | -10.40 | Rossmann-like_a/b/a_fold | interpro domains | IPR014729 | 42 | 16 | 18293 | 2341 |
CARS,WARS2,LARS2,RARS2,MARS,VARS,ETFB,YARS2,WARS,FLAD1,RARS,EPRS,ASNS,TRMU,DPH6,YARS |
| 3.089e-05 | -10.39 | G3BP2 (GTPase activating protein (SH3 domain) binding protein 2) | protein interactions | 9908 | 59 | 21 | 16036 | 2270 |
WDR36,DDX24,FARS2,USP10,ADSL,RNH1,NUP214,POM121,PABPC4,UBC,IGF2BP3,ASCC3,UBAP2,COPS5,RNF2,YARS,BMI1,DDX10,RPL22L1,PABPC1,TERF2 |
| 3.116e-05 | -10.38 | PUF60 (poly-U binding splicing factor 60KDa) | protein interactions | 22827 | 114 | 33 | 16036 | 2270 |
TTN,CUL7,FN1,SIRT7,OLA1,LAMTOR3,SF3A3,IGF2BP2,HNRNPA3,PABPC4,IGF2BP3,HIRIP3,UPF2,IGF2BP1,SRRM2,PABPC1,HNRNPM,NUDC,PTBP2,VIM,SON,SAP30BP,TARS,DDX3X,SYNCRIP,CHD3,COPS5,HNRNPH3,MPV17,GPN1,XPNPEP1,TROVE2,BORCS5 |
| 3.165e-05 | -10.36 | MODULE_8 | MSigDB lists | MODULE_8 | 413 | 82 | 17758 | 2279 |
PTP4A1,SMARCA4,SLC29A1,GYG1,BIRC2,MAP2K3,CAD,DECR1,ASNS,SRSF2,SLC39A7,SSBP1,POLE3,SERPINH1,PEG10,TRIP13,PTPRK,DBN1,RFC4,RBCK1,COL5A2,ITPA,PARP2,GMFB,CAV1,SOX4,MCM2,DSP,CHAF1A,CXADR,PLIN2,PES1,HPRT1,ADNP,COPS5,ARL4A,ADAM9,TPM1,NOLC1,BMI1,TROVE2,RBP1,HMGA2,AK2,MCM6,FN1,TRIP6,ST6GAL1,UBXN1,ALG8,HSD17B10,ARFIP2,APRT,PHLDA2,HDDC2,ETFB,IQGAP2,IGF2BP3,MYC,SEC24C,COPS3,SHMT2,MFAP2,NRIP1,AGL,SLC25A1,HMGCR,FADS1,APEX1,CRIM1,ADSL,PTPN12,EHBP1,PLCB1,ABCF1,UBE2E1,RPA1,FAT1,FDPS,SQLE,UMPS,SLC43A1 |
| 3.213e-05 | -10.35 | MORF_RAD54L | MSigDB lists | MORF_RAD54L | 104 | 29 | 17758 | 2279 |
RFC4,GARS,SKIV2L2,DDX18,SFSWAP,MARS,VARS,BMS1,XPO7,MCM2,ABCF1,TARS,POLR2A,ARIH2,POM121,PABPC4,CHAF1A,CAD,EPRS,TRRAP,EIF2S2,CEBPZ,TNPO3,SCARB1,SSBP1,YARS,XPO6,TRIP13,NUDC |
| 3.221e-05 | -10.34 | salivary_gland | COSMIC cancer mutations | salivary_gland | 1176 | 197 | 17775 | 2278 |
SLC37A3,CDCP1,MVK,ATRX,CSNK2A1,BCOR,PRKCA,MGA,MAP2K3,ZNF804A,ABL2,PDZD2,ZFHX3,RNF111,CHD2,CEP135,FXN,ZMYM2,CDK6,TRIP13,PRKACB,SRPK2,FAM184A,PTPRK,FLNC,CHD9,TNK2,NRAS,HARS,SIRT6,CDK4,ARRDC3,CUX1,KSR2,BRCA1,KMT2C,SOX4,TMEM206,UBTF,GEMIN5,AHNAK,BRCA2,TRRAP,SUFU,TOM1L2,TP53BP1,CSMD3,RUNX1,MAGI1,SYNPO,PTPN14,SEPHS2,AK2,FOXO1,ANKRD17,CLK1,KHDRBS1,PAX2,TRIO,MAPK8IP3,PIK3R4,ZFP36L1,RLF,C1orf50,TGFBR2,CD226,ARID1B,ABCA7,RBM20,RNF40,PI4KB,DHX37,ATXN2,GTF2H1,GTF3C3,ALDH18A1,MAP3K12,TOMM34,ANGPT2,MTHFD1,CAMKK2,MYO10,RB1CC1,PRDM16,ARID5B,TYW1,JMJD1C,TBXAS1,RAP1B,RYR2,OBSCN,ARID1A,SUPT5H,SLC26A11,EXOC6,ZNF783,DAGLA,SYCP2L,ASCC3,LRP1B,BICD1,FAM135A,SPEN,ZZEF1,HK2,CNDP2,PDLIM5,PRKAR2A,ARHGAP10,MAP2K4,SDSL,CYLD,BIRC6,CELSR3,PDK4,PTPRG,CORO6,GBF1,DDX60L,STAM,PLXNB1,PHC2,RPP30,ZNF827,ACD,FMNL1,RPS6KL1,FGGY,SLC38A2,GSTA4,CMPK1,MET,KMT2A,MAML3,SEC24A,SSFA2,PDK1,ADAM32,MRRF,AKAP13,GALK2,ENC1,EDEM2,STK10,FGFR1,TJAP1,HIPK2,RPS6KB1,TROVE2,TRIM36,ZNF507,HMGA2,TNIK,BRAF,MAP3K13,DBF4,SF3A3,ATF7IP,CCDC7,IP6K2,IKBKAP,ENOX1,CSNK1A1,FOXO3,IQGAP2,ABL1,PRKCH,SACS,LARP4B,ERRFI1,SOX6,RPS6KB2,KDM6B,ADAMTSL3,MON1A,CRIM1,AGPAT4,KDM5A,RSBN1,PALLD,PDE3B,C8orf33,PIK3CB,CENPP,SRCAP,NSD1,TRIB3,PXDN,TMEM237,DAGLB,HERC1,DNAJC12,ATM,MYOM2,RPS6KC1,GPATCH4,DDIT3 |
| 3.235e-05 | -10.34 | TEX10 (testis expressed 10) | protein interactions | 54881 | 24 | 12 | 16036 | 2270 |
CUL7,SLX4,GNL3,SIRT7,WDR18,USP42,PTPN12,SENP3,RNF2,MDN1,PELP1,RPA1 |
| 3.246e-05 | -10.34 | transcription elongation from RNA polymerase II promoter | biological process | GO:0006368 | 78 | 24 | 16441 | 2138 |
GTF2H3,TAF1,ELP3,SETD2,TCEB3,IKBKAP,NELFA,SUPT5H,CDC73,POLR2A,TAF9B,TAF2,PAF1,ELL,SUPT4H1,ELP2,GTF2A1,CCNT1,TAF3,CDK9,TAF4,GTF2H1,NCBP2,TAF12 |
| 3.252e-05 | -10.33 | upper_aerodigestive_tract-mouth-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma | 6709 | 947 | 17775 | 2278 |
ARHGAP26,ADAM19,CDCP1,DCP1B,AARS2,NAT10,MKS1,CACNA1H,TUBE1,SBF2,SLC6A8,SYNJ1,LPAR3,AMBRA1,SKI,PDZD2,SREBF2,IKZF5,NEK6,ZFHX3,RABGAP1L,FAAH2,WIZ,KDM5C,HRG,MSANTD2,SRRM2,NRAS,GNL3,EHMT1,KIF15,RFX2,WDHD1,AKAP12,ABCC2,C10orf76,STOML2,DDX3X,AHNAK,BRCA2,LRRC40,TMEM139,MPV17,DIRAS1,RIOK1,VASH2,ZNF532,CARS,BANP,HERC2,TMEM63C,KHDRBS1,TRIO,NHS,BTBD9,RSF1,PDCD7,KCNJ14,PITPNM1,ABCA7,SLC39A11,RSPRY1,CHN1,RBM20,DDX56,UBE3A,EIF2S2,DHX37,INTS7,MCM5,WDR60,GEMIN4,NOC3L,MRPL21,CCDC88C,PRMT5,ZNF518B,MAP3K12,PABPC1,PPA1,SERBP1,SAMD3,ANGPT2,FADS1,IFRD1,STAG1,KCNQ3,MYO10,PRDM16,TYW1,EPS15L1,IDH3G,ZNF512B,RYR2,ATAT1,USP10,MAP7D1,SNAP25,ARRDC4,CPT1A,TRIM37,EVI5,ONECUT2,ZNF655,NCDN,IRS1,DYNC1H1,VPS13C,LRP1B,KPNA1,GTF2A1,PDLIM1,EHMT2,TRAP1,SURF1,BPNT1,WDR33,SRP14,ARHGAP10,RAB11FIP4,ABCA3,DNM3,ZNF516,NPAS2,ATP6V1A,MAB21L3,MYH9,AGAP6,TUBB6,SAFB2,RPGRIP1L,PRKD3,CD96,ESAM,BCAS2,ACD,ZKSCAN1,SETD5,FMNL1,CLCN6,MMP14,C16orf58,ATRIP,INTS12,MSH4,PEG10,MGLL,ZC3H3,LYST,GARS,KMT2D,FAM111B,ARHGEF10,ADAM32,PCNXL2,MEF2D,KCNH3,NUDT15,TTC28,DSP,FKBP3,VPS53,PDE8B,PES1,HLA-DMA,KDM4B,ASTN2,HIPK2,POLR3E,WDR7,FUS,ZBTB11,ANKS1A,LAMA5,CEP170,YEATS2,CATSPERG,BAG1,LRCH1,MORC2,SERINC5,SESTD1,TRAK1,WDR37,ATG2B,TRIM22,POM121,KRI1,SNW1,GATC,ACAP3,UNC13A,ACOT11,LTN1,ARHGAP1,RAPGEFL1,ZNF710,FBXL19,C15orf41,SAMD4A,SOX6,HNRNPM,SPTAN1,DIS3L2,DDHD1,C21orf58,ERICH1,CLYBL,POLK,ARHGAP39,ZC3H18,NXN,RSBN1,FAM126B,PPIP5K2,PDE3B,UBC,KISS1R,RPA1,TOE1,SRCAP,NSD1,BAZ2B,PXDN,ARID3B,HERC1,ACOX1,PTPN4,SORCS2,MTMR1,DOCK6,KDM4C,CUL7,FAM227A,RBM33,TRIM16,WDR13,PPARGC1B,TFIP11,POLR1A,FAM13A,SEC16A,NLE1,GIT2,SCAF8,ABL2,AMPD3,ECM1,ARHGAP18,PHKA1,ANKRD11,HKR1,METTL8,UBAP2L,RAN,ETV1,SLC25A23,FAM184A,SF3A1,CDC37,VPS13B,METTL1,FLNC,DBN1,CHD9,FMNL3,ZNF124,SLC3A2,RBCK1,BAZ2A,SKIV2L2,ANK2,MARCKSL1,LAMA2,BRCA1,KCNH2,KRTCAP2,ZNF91,CCDC28B,PEX1,BSN,LSS,TP53BP1,EEFSEC,PER1,TECPR2,ADAM9,MAGI1,SEPHS2,AOC3,FOXO1,CLK1,NKD2,MEX3A,MAPK8IP3,HSD17B10,ZFP36L1,RLF,ARID1B,DNAH1,SPIRE1,RNF40,DOPEY1,ZNF358,CEP290,PDE10A,SAMD11,VAPB,CTR9,LRSAM1,SNX29,TRAPPC9,TLE3,HAUS6,BCS1L,RNH1,OBSCN,MEX3B,NR2F1,TCF7L2,VAC14,TBC1D2,GRIK4,ATXN7,FAM135A,ITPRIPL1,SYNCRIP,PALB2,TTC38,SNAP23,DNAH17,PPP1R12B,CASS4,HMBS,GGT7,PRKAR2A,USP7,KCTD7,CYLD,PAPD4,UPK3B,ARID2,OSBPL9,NTSR1,GPR143,LAGE3,DENND3,RADIL,PPP1R9A,ZNF121,PELP1,URB1,PLXNB1,CAD,ZNF608,JAG1,GRIN2C,ARMC5,DNAJB6,ZDHHC6,CCDC40,ZFP37,MYH15,ANO8,ETF1,AKNAD1,IPO11,CASP10,CTC1,PRPF19,KDM3B,SEC24A,PCGF3,TEX19,KIRREL2,GLTSCR2,THSD4,VIM,AKAP13,ENC1,NHSL1,EIF3H,TMEM186,TJAP1,BTBD11,EXO1,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,CLEC16A,ITGA2,TSSC1,ZNF436,PRRT3,ZNF18,NFASC,PUS1,EIF2B3,PARD3,DMGDH,ESCO1,MAP3K13,RFX1,C14orf159,VARS,RBM19,ZNF346,FOXP1,CSNK1A1,RMI1,POGZ,ANKRD54,PTPN2,ADH5,FAM50A,SACS,ANXA7,PRICKLE2,DDX31,POLR1B,CPNE7,FAM71E1,ADAMTSL3,MON1A,SMARCAD1,ABCF2,TEX14,TOP3A,DHX34,PEAR1,FERMT2,ARHGEF12,C11orf49,RANGAP1,PALLD,RHOT2,PIK3CB,ARMC3,POLR3A,POLR3G,CDH24,CACNB1,NOL10,TAF4,GLG1,MSH3,BCAS3,USP20,ITGB4,RPS6KC1,XPO6,KIF1B,ZNF292,CGN,LUZP1,TNFRSF21,LRP5L,AARS,UBR5,RAC3,LPIN1,MGA,GIPR,EXOC1,ZFYVE28,SUCLG2,PAK1IP1,VPS52,CHD2,CEP135,MEIS3,FUT11,ZNF646,TBC1D8,DDN,ACADS,DPF3,OSBP2,SETD1B,CUX1,ZDHHC14,DENND4A,DDX60,GZF1,SPOP,OSBPL1A,DDAH2,TRRAP,LSM14A,CCNT1,NSMCE1,CFD,ZNF81,HIC2,VPS13D,SEMA3C,DNAH2,CCNB1IP1,NRP1,ZNF598,ZMAT3,SYNPO,CADM4,PRPF38B,DROSHA,CELSR1,ANKRD17,PRPF31,DLGAP4,CENPB,OPHN1,GTF2IRD1,TGFBR2,MTUS1,IGF2BP3,TECTA,NAV1,PI4KB,NOVA2,ASAP1,SCAF1,USPL1,VWDE,PIGG,IGF2BP1,GTF3C3,LPCAT1,PRPS1,TERF2,FDFT1,ADARB1,USE1,SCAF11,DDX28,RREB1,SYNGAP1,AOC2,PCCA,POLA1,RAPGEF4,RDH10,KIAA0586,RAP1B,PTPN12,ARID1A,PLCB1,SLC26A11,MTR,PHF6,ATP9B,DAGLA,ZNF425,EPRS,ASCC3,MTHFD2,PMEPA1,VCAN,SPEN,ZZEF1,ZBTB12,MED15,ZCCHC6,PURB,SQLE,DPEP1,UMPS,C7orf50,NCOR1,SMYD3,HS2ST1,CPT1C,RTTN,TBKBP1,AMOTL1,SYT17,TRPM2,RWDD1,BIRC6,URB2,HFM1,TMEM104,PLEK2,PTPRG,PABPC1L,TRIM66,IGSF1,PDE3A,CHD7,FLAD1,TERF2IP,ZNF827,ASNS,TMEM184A,SLX4,SHC1,KDM2A,ARMC6,PPID,VGF,SHF,NBEA,TTC3,SSBP1,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,CDK12,CASP8AP2,ZCCHC14,BRD4,GON4L,C1orf228,MTIF2,WDPCP,PREX1,LRRC8A,DLG4,GNL1,SATB2,MEGF11,GALK2,MED16,SETD7,ERC1,CPED1,ZBTB25,VDR,BAZ1A,DNTTIP1,SMARCC1,G6PD,ZNF236,FTSJ1,IFT140,TRMT2A,SLC4A7,MDN1,ANXA2,TBXA2R,PDCD11,SETD6,MID1,NCOR2,SSH2,BRAF,B4GALT5,C10orf2,TCF3,ZNF280C,KIF5C,SLC25A12,FARS2,RTN4,MLH1,MON2,OPA1,GDPD5,FOXO3,FAM8A1,TMCO6,NEDD4,ABL1,ZNF239,DCTPP1,RGS17,PTRF,NISCH,UPF2,COPS7B,NLGN3,DYNC2H1,CELF1,PLEKHG4,NAV3,TSHZ1,FER1L5,SLC40A1,TTLL5,PXN,ZFYVE1,WDFY3,FZD3,KCNMA1,WDR18,PACS1,KLF6,ECH1,SLC23A2,KLHL22,ZDHHC11,DDX50,HELZ,ATM,SVIL,MYOM2,NDUFS5,BRWD3,IPO4,DDIT3,ZNF76,MVK,PHF3,FEM1C,UBN1,NF1,ATRX,PTPRA,TRPM6,PLOD1,BCOR,SNAPC4,EDC3,RTN1,ZNF804A,DST,THADA,YLPM1,LONRF2,ANAPC11,SLC39A7,MYH3,RELB,ZEB1,JOSD1,POLR3B,SLC27A5,SLC35C2,NDUFA6,YARS,TRIM14,CARM1,LONP1,TIMM50,LAMA4,ZBTB17,DTNB,TNK2,DEAF1,GPM6A,FBXW4,SESN2,TRIM13,TXLNG,CMIP,ARRDC3,VWCE,KSR2,MTHFD1L,SGK2,KMT2C,CDHR3,YTHDF2,TIMM44,CHAF1A,CCDC3,EPN2,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,FAM114A2,RLTPR,CSMD3,ABCC3,GALNT10,EME1,CLU,ZNF397,DCAF5,DMTF1,MTCH1,SLC12A7,FBXO45,PIGN,CHST11,FN1,SEC24D,TAF1,ZCCHC8,STXBP6,SMG7,MED13L,PHGDH,RHBDD1,CEP164,ELL,SIPA1L3,MCAM,ATXN2,SEMA3D,CCDC112,GLTP,CCDC124,PRF1,N4BP2,HSD17B14,ZNF629,KRT20,PDE4A,ELP3,JMJD1C,TBXAS1,ZFP14,WWC1,LIG4,EIF2A,CORIN,ANKRD20A4,SYT1,AGAP1,DNAH14,ISG15,MGAT2,APBB3,ATAD5,MYBBP1A,KIAA0355,INTS5,FAT1,KIAA0754,SDCCAG8,TMEM117,CDKAL1,ZFP90,FNBP1L,NR2C2AP,FEZ2,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,SMARCA4,ARSJ,PIBF1,GBF1,SBDS,VPS18,FARSA,CAMTA2,PPFIBP1,SNTG2,ZNF142,ITGAX,TMEM120B,HTRA2,AUP1,MOSPD1,HN1,TMLHE,PRAME,FAM172A,SFSWAP,NLN,ATXN1,R3HDM1,ATP8B2,UBR4,PUSL1,WARS,RAD54B,PLIN2,ALAD,IKZF4,DUS3L,HNRNPR,ADNP,ZNF557,CEBPZ,WDR73,SRFBP1,SCARB1,TMEM101,NFRKB,USP11,TSPAN5,SMG1,YDJC,DNAJC2,BCKDK,SULT1C2,SH2D3A,ARL15,PDE4B,NSUN6,PPHLN1,ATF7IP,IGF2BP2,SEMA3E,SOGA1,ENOX1,MFHAS1,GFM2,BMP6,PIP4K2A,MFSD10,SFI1,MAN1A1,IL17RE,PRKCH,CTNNBL1,SCN1B,SEC24C,DSG2,STC2,SHMT2,LDLRAD3,ERI3,DMRT1,MICAL3,TOP1,MARCH9,KDM6B,DNMBP,FGF2,CRIM1,PSPC1,KDM5A,ANKMY2,SCFD2,ASAP3,PHACTR2,ARHGAP32,PDE2A,MEN1,ZNF407,EIF5B,NAALADL2,TARS,RERE,CTIF,ZNF221,ALG5,DAGLB,WDR35,MBD6,NFKBIB,MMP16,ZAK,ZSWIM6,HRH1,CTXN1 |
| 3.252e-05 | -10.33 | WHEP_TRS_1 | prosite domains | PS00762 | 5 | 5 | 11866 | 1504 |
MARS,EPRS,GARS,HARS,WARS |
| 3.252e-05 | -10.33 | WHEP_TRS_2 | prosite domains | PS51185 | 5 | 5 | 11866 | 1504 |
MARS,EPRS,GARS,HARS,WARS |
| 3.305e-05 | -10.32 | ZHANG_BREAST_CANCER_PROGENITORS_UP | MSigDB lists | ZHANG_BREAST_CANCER_PROGENITORS_UP | 401 | 80 | 17758 | 2279 |
PAIP2,ANAPC1,NVL,UCHL5,PDS5B,ZNF148,TTC3,BCAP29,SSBP1,MET,LYRM5,TRIP13,CASP8AP2,TMPO,SAP30,NRAS,AEBP2,PDK1,SLC38A1,HARS,RNMT,NFIA,ATXN1,BRCA1,MARCH6,MCM2,KIF16B,TAF2,SLC7A1,IFT81,RBBP8,TRRAP,TP53BP1,TIMM17A,LRRC40,BMI1,ZNF532,PTPN14,TMEM33,SEPHS2,TNIK,WDR75,ZCCHC8,ST6GAL1,STXBP6,DBF4,C11orf54,CDC73,CEP164,ZNF239,ADH5,PEX7,TSPAN2,DSG2,N4BP2,ACTR3B,CAV2,SERBP1,MYB,MTHFD1,PSAT1,PPAT,PSPC1,POLA1,UTP15,PPIP5K2,TRIM37,PLCB1,PHF6,RPA1,PWP1,TASP1,NME7,SYNCRIP,ORC5,TMEM117,ZRANB2,CNOT6,POLR1C,ADK |
| 3.307e-05 | -10.32 | GCM_BMPR2 | MSigDB lists | GCM_BMPR2 | 79 | 24 | 17758 | 2279 |
HERC2,SNX27,TSPYL4,MYO10,NFIA,RTN4,UBE2K,TRIM37,FOXO3,POGZ,SPIRE1,RERE,DYNC1H1,ZFAND3,FBXO21,KIDINS220,NUP133,CLEC16A,VPS52,GSTA4,RAN,PREPL,TBCK,KIF1B |
| 3.340e-05 | -10.31 | POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220kDa) | protein interactions | 5430 | 265 | 62 | 16036 | 2270 |
CUL7,SUPT6H,NF1,UBN1,SIRT7,TRAK1,CSNK2A1,SMARCA4,ATF7IP,CCNL2,CDC73,NEDD4,ZC3H13,SMARCB1,ABL1,ELL,SUB1,SRSF2,USPL1,MYC,WAC,ZNF326,GTF2H1,GTF3C3,POLR3B,CPSF3,NRIP1,KMT2A,CDK12,CASP10,CPSF3L,PRPF19,KMT2D,SETD1B,SETD2,ELP3,TCEB3,WDHD1,BRCA1,NELFA,MEN1,MCM2,SUPT5H,POLR3A,POLR2A,RPA1,VDR,PAF1,SUPT4H1,SSU72,HNRNPR,CCNT1,INTS5,EEFSEC,CDK9,CUL2,H2AFX,PQBP1,ATM,GPN1,FUS,SMYD3 |
| 3.402e-05 | -10.29 | caecum | COSMIC cancer mutations | caecum | 14975 | 1983 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,RNMT,KLHL23,LIMA1,EXOC6B,UPP1,EHMT1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,FGFBP1,CCDC85B,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,VTI1A,DDR2,CD99L2,FAM122B,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,RPGRIP1L,ZBED2,CD96,ESAM,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,TRMT12,ZC3H3,KIAA1549,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,MORC2,SHQ1,XRRA1,ATG2B,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,SPTAN1,TTPAL,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,NCKIPSD,ANKRD11,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,MARCKSL1,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,C1orf122,BSN,DYRK1B,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,LYRM2,ARID1B,SPIRE1,RNFT2,ZNF358,CEP290,MBD2,VPS72,VAPB,CTR9,WNT16,PNPLA3,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,SUCLG1,ARID2,SLC48A1,OSBPL9,NTSR1,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,KIRREL2,VIM,CA5B,NHSL1,ZNF251,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,USP20,TMEM219,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,FAM127A,OSBP2,C2orf76,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,TMEM206,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,PRPF38B,C9orf78,CDC42EP2,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,PDCD5,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,RTFDC1,FDFT1,EXOSC2,IFNGR2,KIAA1143,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,TPRA1,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,ATP9B,SEC31A,CAT,ASCC3,C6orf141,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,DECR1,SLX4,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,MBTD1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,GUF1,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,TMEM216,KSR2,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,TIMM10,NAMPT,ELL,HVCN1,ZNF354A,ISPD,ZCCHC7,PRF1,ATP6V0D1,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,DMXL2,TCF12,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,COBLL1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,FHIT,ADCK4,ITGAX,VCL,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,PRAME,GRHL3,ATXN1,POU2F1,MRRF,DKC1,EDEM2,UBR4,S100A16,BATF3,ARMC4,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,ATF7IP,WDR26,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,ZSWIM6,NIT1,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,AMBRA1,NOS1AP,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,RABGAP1L,RASSF3,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,LYRM5,HRG,FXN,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,PLEKHM3,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,ZNF266,TMEM139,RBP1,MEF2C,TNNC1,HERC2,CARS,EP400,CLDN15,TRIP6,SIRT7,PRAF2,NHS,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ZNF326,NOC3L,PRMT5,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,PEA15,TIMM8B,BDNF,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,EVI5,ABCF1,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,NT5C,GSTA4,CEP63,MTHFD2L,LSM10,MALL,GARS,KRT7,STAMBP,FAM111B,NPM3,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,JMJD6,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,NUDC,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,IL6R,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,UBAP2L,ZNF85,RAN,ETV1,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,SLC3A2,ZNF124,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,GDPD1,NOL6,COL4A3BP,BRCA1,FLVCR1,ZNF91,KIF16B,PEX1,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,TMEM158,CHMP4C,XYLB,SEPHS2,SARS,AOC3,OXNAD1,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,TRIM15,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,NAPA,PRKAR2A,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,PPP2R2A,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,HIRIP3,ZFP37,ETF1,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,C1QTNF1,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,ZNF18,NFASC,PUS1,ZNF589,AP2S1,PKIB,ATXN7L2,UNC13D,MAP3K13,FAM46B,C14orf159,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,ANXA7,CWC27,HIST2H3D,PRICKLE2,GREB1,DDX31,CD44,PCK2,FBXO31,ADAMTSL3,GINS3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,SRBD1,GPC2,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,RNF111,VPS52,ME1,PRADC1,CEP135,MEIS3,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,FAM122C,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,VWDE,SLC16A9,IGF2BP1,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,PMEPA1,UBAP1,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,PURB,PEX13,MACROD1,IQSEC2,MAP2K4,RTTN,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,ZBTB37,URB2,RIBC2,HFM1,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,HTR7,YIPF2,DNAJA3,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,NEDD4,MAD2L2,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,TRIAP1,PMPCA,HARS2,UPF2,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,C19orf43,FZD3,KCNMA1,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,BRWD3,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,YLPM1,LONRF2,ATG3,ZNHIT6,GPR87,RELB,HYAL1,IPP,PCOLCE2,POLR3B,CCDC121,OGG1,TRIM14,PRKACB,TRIP13,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BANF1,CCDC112,SEMA3D,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WWC1,C11orf65,PRDM1,DNAH14,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,PTRH2,KIAA1328,ZFP90,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SLC25A11,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SH2D3A,C17orf80,DBF4,H2AFJ,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,MFSD10,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,CLDND1,TTC17,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,NCBP2,ZRANB2,MBD6,PREPL,MMP16,ZAK,ARHGAP27,SLC16A10,HRH1 |
| 3.420e-05 | -10.28 | WHEP-TRS_dom | interpro domains | IPR000738 | 5 | 5 | 18293 | 2341 |
MARS,EPRS,GARS,HARS,WARS |
| 3.440e-05 | -10.28 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | 169 | 41 | 17758 | 2279 |
ZNF76,FOXO1,UBXN1,ARFIP2,SF3A3,RPS6KA5,PCYOX1L,METTL16,C6orf48,RNFT2,CNST,PMPCA,MAD1L1,VPS52,ZFP37,SYNJ2,SLC25A23,POLR1E,RABEPK,ZCCHC14,EXOSC2,EVL,IL11RA,GON4L,TSPYL4,NPM3,TBRG4,ADSL,RSBN1,DKC1,ZNF407,LYRM7,ZNF251,APBB3,CHD3,DNAJA3,USP20,ATM,ZNF32,XPO6,IPO4 |
| 3.450e-05 | -10.27 | SEC23A (Sec23 homolog A, COPII coat complex component) | protein interactions | 10484 | 77 | 25 | 16036 | 2270 |
SEC24A,CARS,GARS,CUL7,NARS,SEC24D,SIRT7,PSMA1,PSMG1,SUMO3,XPO7,SEC16A,TTC1,SEC31A,DUS3L,THADA,SEC24C,CUL2,SDCBP2,HIRIP3,SERPINH1,USP11,TPM1,TROVE2,PRMT3 |
| 3.506e-05 | -10.26 | RAF_UP.V1_DN | MSigDB lists | RAF_UP.V1_DN | 186 | 44 | 17758 | 2279 |
EFNB2,TCF12,IFT57,ID1,SHQ1,C16orf45,SMAD7,MED13L,ID2,ENAH,TGFB2,CSTA,SLC1A1,DDIT4,RRN3,ABCA12,THADA,PMAIP1,STC2,GREB1,S100A14,PCSK6,MYB,GDAP1,PCGF3,PTBP2,MYO10,TFPI,JMJD1C,SATB2,CAV1,SOX4,PALLD,TBC1D16,PLCB1,DKK1,IRS1,PXDN,SNAP23,FTSJ1,HSPB8,SLC16A1,DNAJC12,ZNF32 |
| 3.551e-05 | -10.25 | GCM_RAP2A | MSigDB lists | GCM_RAP2A | 34 | 14 | 17758 | 2279 |
ZFAND3,SNX27,HMBOX1,SPAG9,KIDINS220,TEAD1,CLEC16A,ZFP14,LRRC8A,ENAH,RAN,MTMR1,RAB10,SPIRE1 |
| 3.666e-05 | -10.21 | GENTILE_UV_LOW_DOSE_DN | MSigDB lists | GENTILE_UV_LOW_DOSE_DN | 65 | 21 | 17758 | 2279 |
HMGA2,CRADD,PRIM2,MYO10,PAFAH1B1,POLA1,PTPRM,C16orf45,SATB2,PIBF1,EHBP1,ERC1,DDIT4,ZNF804A,G6PD,SEMA3C,MET,DDX10,SAMD4A,NAV3,PTPRK |
| 3.726e-05 | -10.20 | WHEP-TRS | pfam domains | PF00458 | 5 | 5 | 16629 | 2165 |
MARS,EPRS,GARS,HARS,WARS |
| 3.798e-05 | -10.18 | astrocytoma_Grade_III | COSMIC cancer mutations | astrocytoma_Grade_III | 1611 | 259 | 17775 | 2278 |
ARHGAP26,ZNF292,PRKCA,AMBRA1,PCDH7,ZFHX3,SYN2,RASSF3,MAD1L1,PDS5B,ME1,FTSJ3,NRAS,RNMT,PTPRM,EXOC6B,RFX2,PLEKHM3,ZDHHC14,SON,GNAI1,SLC7A1,BRCA2,TRRAP,BDH2,VPS13D,SEMA3C,DNAH2,ZMAT3,PTPN14,EFNB2,IFT57,DROSHA,CELSR1,OPHN1,GTF2IRD1,IGF2BP3,CHN1,TECTA,PRKCE,CNST,SLC38A5,SCAF1,SLC16A9,SAMD13,ANP32B,COQ3,PABPC1,SERBP1,IFRD1,STAG1,ALG6,KCNQ3,PRIM2,PRDM16,ARID5B,RAPGEF4,RYR2,SMARCD3,ST6GALNAC3,PLCB1,MBNL2,SLC26A11,ATP9B,VPS13C,LRP1B,ZZEF1,MED15,ZCCHC6,PDLIM5,TRPM2,ZNF516,HFM1,VTI1A,MYH9,PTPRG,LCLAT1,EEA1,ZNF827,ABCA12,KIAA1549,GARS,KMT2D,EIF3J,SLCO6A1,PCNXL2,MEF2D,MED16,FGFR1,MSX2,CAMK2D,WDR7,LARGE,MDN1,ANKS1A,MORC2,COMMD10,HMGA2,BRAF,TTC27,WDR37,MON2,MLH1,MBNL1,NEDD4,TAF3,UNC13A,LARP4B,SAMD4A,SOX6,ULBP1,TSHZ1,AGPAT4,ARHGAP39,KLHL22,SRCAP,PXDN,POLE2,ATM,SLCO5A1,APAF1,PHF3,ATRX,NF1,PPARGC1B,KIF5A,SLC25A21,BCOR,FAM13A,SEC16A,SNAPC4,SMARCB1,ZNF804A,RTN1,ARHGAP18,THADA,YLPM1,MARVELD2,ANAPC11,GPATCH1,LONP1,DSC3,FLNC,CHD9,DTNB,ZNF124,ABCC4,HARS,ANK2,KSR2,BRCA1,LAMA2,KMT2C,SGK2,ZNF91,CHAF1A,GLS,SUFU,INSIG1,DPP4,CSMD3,GALNT10,MAGI1,TNRC6A,USP15,OXNAD1,LRRC28,NKD2,MED13L,LYRM2,RNF40,ELL,ABCA5,ISPD,SEMA3D,CCDC167,GMDS,ZCCHC7,SNX29,NT5E,RANBP6,TRAPPC9,ELOVL6,SETD2,ZFP14,OBSCN,WDR25,CORIN,TCF7L2,DNAH14,FAT1,SDCCAG8,SNX24,EXOC4,PPP1R12B,TMEM117,PRKAR2A,USP7,PCNT,UPK3B,ARID2,SMARCA4,LPCAT3,ARSJ,PPP1R9A,RAET1E,CAD,BRE,RPS6KL1,SNTG2,CCDC40,MYH15,FHIT,MET,PHLDB2,FAM172A,COL5A2,SFSWAP,UBR4,USP36,ARMC4,CLEC16A,KLF4,ATG7,EIF2B3,PARD3,SMG1,KLC4,CLSTN2,ATF7IP,IGF2BP2,SEMA3E,MFHAS1,IQGAP2,MAN1A1,PRKCH,IL17RE,ERI3,LDLRAD3,TTC17,DMRT1,HSD17B12,CRIM1,DHX34,ARHGAP32,MEN1,EIF5B,NAALADL2,POLR3A,CTIF,MKX,TPD52L2,CDH24,ANKRD30BL,BCAS3,RBM26,MIPOL1,ZAK,ZSWIM6 |
| 3.870e-05 | -10.16 | V$CHOP_01 | MSigDB lists | V$CHOP_01 | 227 | 51 | 17758 | 2279 |
CARS,PTCD2,TTN,SARS,GNB3,TRERF1,ZBTB37,PID1,PPP2R2A,ID2,RNF43,BHLHE40,HMOX2,MBNL1,AHCYL2,PCDH7,SRSF2,ATG3,CACNB2,SLC38A2,TNPO3,ETF1,FUT11,CDK6,SERBP1,MOSPD1,SRPK2,MAML3,KDM3B,SESN2,GARS,GPHN,JMJD1C,EIF4A2,PRDM1,SOX4,SLC35D1,PHF6,HERPUD1,RAD54B,VDR,DYRK1B,AHNAK,SYNCRIP,PER1,ATM,TBL1X,ZBTB11,ZNF532,ATXN7L2,MEF2C |
| 3.875e-05 | -10.16 | NOP2 (NOP2 nucleolar protein) | protein interactions | 4839 | 120 | 34 | 16036 | 2270 |
NIFK,CUL7,MINK1,UTP14A,DDX18,SIRT7,NAT10,RSL1D1,NOP56,DDX56,MPHOSPH10,VPS52,RNF2,NOC3L,FBL,ZC3H3,FTSJ3,TOP1,SRPK2,DDX24,SKIV2L2,GNL3,NOL6,NFIA,BRCA1,DKC1,RBM28,NOP58,PUM3,PES1,MYBBP1A,COPS5,CEBPZ,NOLC1 |
| 3.875e-05 | -10.16 | SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2) | protein interactions | 6601 | 120 | 34 | 16036 | 2270 |
SART1,ARID2,DPF2,SIRT7,CSNK2A1,SMARCA4,ARID1B,SMARCB1,TERF2IP,CAD,CHD7,YLPM1,BANF1,RELB,SHMT2,RNF2,GTF3C3,CARM1,SF3A1,DPF3,KDM5B,TXLNG,SMARCAD1,ATXN1,SMARCD3,ARID1A,BRCA1,RPA1,SMAD3,SMARCC1,ADNP,CHD3,NCOR1,PSAP |
| 3.888e-05 | -10.16 | lymph_node | COSMIC cancer mutations | lymph_node | 1781 | 283 | 17775 | 2278 |
CGN,CDCP1,DCP1B,CACNA1H,PRKCA,UBR5,PCDH7,PDZD2,ZFHX3,NSRP1,PDS5B,FXN,CDK6,SPAG6,NRAS,WLS,PTPRM,AKAP12,DDX60,STOML2,BRCA2,SEMA3C,GREB1L,SPOCK3,NMD3,MEF2C,HERC2,EP400,CELSR1,TRIO,PIK3R4,CENPB,TGFBR2,ABCA7,SLC39A11,ANXA10,TECTA,PRKCE,DDX56,CNST,PI4KB,USPL1,SCAF1,ATIC,MYC,ZNF326,MAP3K12,FADS1,SIK3,RB1CC1,EPS15L1,EIF4A2,KIAA0586,RYR2,ARID1A,PLCB1,MBNL2,ZNF655,DAGLA,SEC31A,ASCC3,VPS13C,LRP1B,NME7,HIF1A,CCDC85B,MACROD1,PDLIM5,ARHGAP10,MAP2K4,BIRC6,URB2,PDK4,MYH9,TMEM104,IGSF1,PDE3A,ACD,ABCA12,PPID,MMP14,TTC3,CMPK1,KMT2A,LYST,KMT2D,PDK1,ARHGEF10,SLCO6A1,SATB2,GALK2,KCNH3,STK10,FGFR1,ZFAND3,IQCH,ASTN2,HIPK2,SLC4A7,RPS6KB1,MDN1,ZBTB11,NOLC1,ANKS1A,YEATS2,TROVE2,HMGA2,BRAF,TTC27,TCF3,IP6K2,RNASEH2B,IKBKAP,FOXO3,MBNL1,KRI1,ABL1,NEBL,SDCBP2,PMPCA,CELF1,SOX6,SPTAN1,NAV3,TSHZ1,WDFY3,ZC3H18,PACS1,ZNF467,TRIB3,PXDN,ATM,SVIL,MYOM2,SORCS2,ADK,ANAPC4,KDM4C,DDIT3,STK4,MVK,NF1,FANCD2,SLC25A21,CSNK2A1,MAP2K3,PCYOX1L,SMARCB1,ABL2,PHKA1,ANAPC10,ZMYM2,PRKACB,PTPRK,SRPK2,CEP128,DSC3,TNK2,GPM6A,TRIM13,KATNAL1,ANK2,CDK4,KSR2,SOX4,KMT2C,TCTN1,CRYBG3,YTHDF2,TMEM132B,MSRA,E2F4,EEFSEC,TNFRSF1A,ADAM9,CSMD3,BEND6,CHMP4C,XYLB,SEPHS2,AK2,FOXO1,ITFG1,CLK1,TAF1,DPF2,MAPK8IP3,ZFP36L1,EVPL,ARID1B,RNF40,KIAA1958,HVCN1,GTF2H1,ALDH18A1,ZCCHC7,NRIP1,SNX29,MTHFD1,KRT20,CAMKK2,PRDM1,SUPT5H,AGAP1,VAC14,TCF7L2,HK2,CDKAL1,DTD1,PRKAR2A,PDSS2,TCF12,DMXL2,CYLD,SLC5A5,GPR143,SMARCA4,LPCAT3,SSBP2,DENND3,PPP1R9A,KDM1A,BRE,SOCS1,GRIN2C,RPS6KL1,FGGY,SNTG2,ANKRD24,ETF1,FHIT,AKNAD1,MET,SKIV2L,SSFA2,TFCP2,PARP2,SFSWAP,AKAP13,EIF3H,BTBD11,CLEC16A,PRRT3,MED20,HEATR1,TSPAN5,SMG1,PARD3,TNIK,MAP3K13,DBF4,CLSTN2,ATF7IP,SEMA3E,RBM19,CSNK1A1,MFHAS1,PIP4K2A,SFI1,PRKCH,PRICKLE2,CPNE7,FBXO31,RPS6KB2,KDM6B,ADAMTSL3,CRIM1,SCFD2,PEAR1,YIPF3,MEN1,PALLD,NAALADL2,PIK3CB,CHCHD6,CENPP,RERE,ZNF708,ZRANB2,RPS6KC1,MIPOL1,ZSWIM6,CTXN1 |
| 3.898e-05 | -10.15 | FORTSCHEGGER_PHF8_TARGETS_DN | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_DN | 732 | 131 | 17758 | 2279 |
CGN,TNFRSF21,FANCD2,CCNL2,PRKCA,ABL2,RABGAP1L,RELB,HYAL1,POLE3,SEH1L,TNK2,FAM127A,OSBP2,TCEB3,GMFB,NFIA,AKAP12,EFHC1,CAV1,CXADR,LSS,SUPT4H1,AHNAK,TOM1L2,TRMT5,TMEM139,AHNAK2,WDR66,SYNPO,TMEM158,SPOCK2,TNNC1,FN1,ZHX3,ST6GAL1,STXBP6,OPHN1,TATDN3,HR,NDRG4,LPCAT1,MAP3K12,SNX29,NT5E,PEA15,ANAPC13,RAP1B,PTPN12,OBSCN,MAPK1IP1L,MAP7D1,ISG15,ZNF655,NAP1L5,NME7,NSF,FGFBP1,RRAGA,SQLE,CNOT6,SMYD3,HS2ST1,SYT17,PAPD4,UROD,TMEM183A,TNXB,PBX1,TMEM177,PLEK2,FLNB,ANKRD13A,KCTD11,UBR1,DNAJB6,MRPS27,MGLL,TSPAN14,DENND1A,PHLDB2,FAM172A,STAMBP,THSD4,LGALS1,PCNXL2,GNL1,CCNDBP1,ERC1,S100A16,TPK1,VDR,HNRNPR,PRRT3,FAHD1,UNC13D,B4GALT5,FAM46B,CHCHD10,GDPD5,GFM2,MBNL1,NEDD4,DCTN4,KDELC1,PTGS1,ARHGAP1,DYNC2H1,CELF1,PNMA1,PLEKHG4,C12orf4,PAQR6,ARNTL2,PFKFB4,PXN,VPS37A,TRNP1,AGPAT4,RAP1GDS1,OASL,KLF6,NEU1,DKK1,INF2,FBXO21,ARID3B,MSH3,ITGB4,KIF1B,NUDT22 |
| 3.923e-05 | -10.15 | XRCC5 (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) | protein interactions | 7520 | 186 | 47 | 16036 | 2270 |
CUL7,JUP,FN1,ATRX,SIRT7,CSNK2A1,TERF2IP,APLF,FMNL1,MYC,RNF2,POLE3,YARS,PRMT3,TERF2,TOP1,RPS6KB2,TMPO,DNMBP,APEX1,NARS,SIRT6,PPARG,POLA1,SMARCAD1,EIF3J,POU2F1,LIG4,BRCA1,SUPT5H,TCF7L2,POLR2A,ISG15,CHAF1A,RPA1,BAZ1A,PAF1,DYNC1H1,MSX2,SUPT4H1,CDC16,TP53BP1,CUL2,H2AFX,ATM,BMI1,XRCC4 |
| 3.946e-05 | -10.14 | SNW1 (SNW domain containing 1) | protein interactions | 22938 | 150 | 40 | 16036 | 2270 |
SART1,NCOR2,SARS,CUL7,TFIP11,PLRG1,SIRT7,TRIM15,VARS,PPIL1,UBR5,SKI,CTNNBL1,CWC27,LRP2BP,MYC,BUD31,RNF2,KMT2A,PABPC1,TOP1,PRPF19,SNU13,HARS,SKIV2L2,HSPA5,ABCF2,MEN1,SMAD3,VDR,SKIL,CCNT1,HNRNPR,CDK9,CUL2,PRPF4,NCOR1,RBPJ,BMI1,ZMAT3 |
| 3.966e-05 | -10.14 | ORGANELLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | ORGANELLE_ORGANIZATION_AND_BIOGENESIS | 466 | 90 | 17758 | 2279 |
NF1,PAFAH1B1,KIF5A,MYO7A,TNXB,MYH9,TUBE1,SIRT2,PLEK2,RAC3,FLNB,NOP56,TERF2IP,DST,ACD,PMAIP1,DNAJB6,PDS5B,DTNBP1,HIRIP3,RAN,CARM1,TIMM50,KAT8,DBN1,EVL,ATG9A,LIMA1,EHMT1,PREX1,HDAC8,DKC1,CHAF1A,PEX1,TIMM44,TAMM41,SUPT4H1,BRCA2,SMARCC1,TIMM17A,PAM,MPV17,FIS1,SEPT5,NOLC1,AP2S1,MID1,MAPT,HMGA2,SSH2,TTN,CDC42EP2,ARFIP2,MAP1S,KIF5C,RSF1,OPA1,RPS6KA5,NDUFS7,ABL1,DOPEY1,PEX7,NEBL,SUV39H2,GEMIN4,DYNC2H1,FBL,AMOT,MAP3K12,TOMM34,SLC25A1,TERF2,KRT20,EXOSC2,ARID1A,EIF2A,RHOT2,NOP58,MFN2,NSD1,ATXN7,FSCN1,SNAP23,SET,MSH3,PEX13,NDUFS5,ARHGAP10,KIF1B,KAT6A |
| 3.975e-05 | -10.13 | large_intestine-caecum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-caecum-carcinoma-adenocarcinoma | 14963 | 1981 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,EIF4E3,NRAS,RNMT,KLHL23,LIMA1,EXOC6B,UPP1,EHMT1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,SHISA5,ABCC2,SLC9A5,ZNF197,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,SYNGR2,BDH2,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,ARRDC4,TRIM37,SRA1,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,KPNA1,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,FGFBP1,CCDC85B,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,VTI1A,DDR2,CD99L2,FAM122B,ISG20L2,NUP43,ST3GAL6,LCLAT1,ZMAT2,MCM9,RPGRIP1L,ZBED2,CD96,ESAM,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,TRMT12,ZC3H3,KIAA1549,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,SLC35D1,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,MORC2,SHQ1,XRRA1,ATG2B,TRIM22,IP6K2,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,PNMA1,SPTAN1,TTPAL,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,NCKIPSD,ANKRD11,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,MARCKSL1,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,C1orf122,BSN,DYRK1B,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,DPP4,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,ITFG1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,LYRM2,ARID1B,SPIRE1,RNFT2,ZNF358,CEP290,MBD2,VPS72,VAPB,CTR9,WNT16,PNPLA3,CWF19L2,SNX29,NIPSNAP1,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,BCCIP,USP7,MPI,SART1,ID1,OLFM2,PAPD4,SUCLG1,ARID2,SLC48A1,OSBPL9,NTSR1,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,KIRREL2,VIM,CA5B,NHSL1,ZNF251,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,PLAC8L1,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,SAMD5,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,USP20,TMEM219,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRR4,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,FAM127A,OSBP2,C2orf76,EFHC1,CAMSAP2,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,TMEM206,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,PRPF38B,C9orf78,CDC42EP2,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,PDCD5,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,RTFDC1,FDFT1,EXOSC2,IFNGR2,KIAA1143,ANAPC13,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,ARID1A,TPRA1,EHBP1,ANGPTL4,MTR,SLC26A11,ZNF850,ATP9B,SEC31A,CAT,ASCC3,C6orf141,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,SYT17,BIRC6,KIAA0232,TMEM104,POP5,PLEK2,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,BLOC1S2,DECR1,SLX4,ARMC6,PPID,LPIN2,SOCS6,MRPS27,DTNBP1,SHF,TTC3,CMPK1,CDK12,CASP8AP2,BRD4,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,ZBTB25,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,MBTD1,LARGE,IFT140,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,GUF1,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,LYRM4,EIF3C,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,TMEM216,KSR2,MTHFD1L,PITPNB,COTL1,SGK2,KMT2C,ST3GAL5,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CRCP,CSMD3,ASB3,CLU,EME1,DCAF5,MTCH1,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,UBXN1,PCSK7,SMG7,QSER1,EVPL,TIMM10,NAMPT,ELL,HVCN1,ZNF354A,ISPD,ZCCHC7,PRF1,ATP6V0D1,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,DMXL2,TCF12,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,COBLL1,TBCCD1,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,FHIT,ADCK4,ITGAX,VCL,C6orf89,AUP1,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,PRAME,GRHL3,ATXN1,POU2F1,MRRF,DKC1,EDEM2,UBR4,S100A16,BATF3,ARMC4,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,DYM,KLC4,PDE4B,VPS45,ATF7IP,WDR26,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,STC2,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,SLC6A16,ARNTL2,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,METTL23,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,ZSWIM6,NIT1,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,AMBRA1,NOS1AP,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,RABGAP1L,RASSF3,FAAH2,C12orf76,PDS5B,WIZ,ZNF148,LYRM5,HRG,FXN,CDK6,WLS,PTPRM,GNL3,RFX2,MSRB3,AKAP12,PLEKHM3,C10orf76,RBM28,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,ZNF266,TMEM139,RBP1,MEF2C,TNNC1,HERC2,CARS,EP400,CLDN15,TRIP6,SIRT7,PRAF2,NHS,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ZNF326,NOC3L,PRMT5,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,PEA15,TIMM8B,BDNF,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,EVI5,ABCF1,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,CLASRP,LEMD3,SURF1,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,ACTR3,PDK4,MYH9,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,NT5C,GSTA4,CEP63,MTHFD2L,LSM10,MALL,GARS,KRT7,STAMBP,FAM111B,NPM3,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TMEM141,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,JMJD6,TGFB2,BHLHE40,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,NUDC,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ERICH1,POLK,ARHGAP39,FRA10AC1,MRPS10,R3HDM2,FAM126B,IL6R,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,ETFDH,RARS,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,UBAP2L,ZNF85,RAN,ETV1,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,SLC3A2,ZNF124,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,GDPD1,NOL6,COL4A3BP,BRCA1,FLVCR1,ZNF91,KIF16B,PEX1,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,DLX2,RNF214,TMEM158,CHMP4C,XYLB,SEPHS2,SARS,AOC3,OXNAD1,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,TRIM15,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,VAC14,PGD,PWP1,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,NAPA,PRKAR2A,RNF114,KCTD7,NDUFA5,CYLD,RBFOX2,LPCAT2,GPR143,PPP2R2A,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,HIRIP3,ZFP37,ETF1,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,CPOX,C1QTNF1,TMEM123,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,ATP5D,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,TIMM17A,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,ZNF18,NFASC,PUS1,ZNF589,AP2S1,PKIB,ATXN7L2,UNC13D,MAP3K13,FAM46B,C14orf159,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,C15orf57,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,ANXA7,CWC27,HIST2H3D,PRICKLE2,GREB1,DDX31,CD44,PCK2,FBXO31,ADAMTSL3,GINS3,ZNF654,ZMYM5,TPM4,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,C20orf196,TMEM237,SRBD1,GPC2,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,MYCBP2,POLB,CGN,PRDX6,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,RNF111,VPS52,ME1,PRADC1,CEP135,MEIS3,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,NR6A1,ATG9A,ALDH1L2,NOL8,EYA3,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SAP30BP,MAK16,SH3GL1,SKIL,FAM122C,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,TXN2,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,TGFBR2,CHD5,CD226,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,VWDE,SLC16A9,IGF2BP1,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,SIK3,DDX28,SYNGAP1,SIGMAR1,AOC2,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,NSF,ZZEF1,D2HGDH,ZBTB12,RIOK3,PURB,PEX13,MACROD1,IQSEC2,MAP2K4,RTTN,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,ZBTB37,URB2,RIBC2,HFM1,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,NAA35,C18orf21,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,MTIF2,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,HTR7,YIPF2,DNAJA3,ZNF236,ACP1,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,REEP5,TMCO6,NEDD4,MAD2L2,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,TRIAP1,PMPCA,HARS2,UPF2,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,C19orf43,FZD3,KCNMA1,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,RNF138,MYOM2,BRWD3,SLC43A1,STK4,LRRC41,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,YLPM1,LONRF2,ATG3,ZNHIT6,GPR87,RELB,HYAL1,IPP,PCOLCE2,POLR3B,CCDC121,OGG1,TRIM14,PRKACB,TRIP13,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,TXLNG,ZNF680,SLC38A1,CMIP,GPCPD1,HDAC8,CAV1,SOX4,ZSCAN2,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,BANF1,CCDC112,SEMA3D,NRIP1,POLR1E,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WWC1,C11orf65,PRDM1,DNAH14,UBAP2,ATAD5,MYBBP1A,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,PTRH2,KIAA1328,ZFP90,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SLC25A11,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SH2D3A,C17orf80,DBF4,H2AFJ,NSUN6,CLSTN2,PPHLN1,LETMD1,CCDC7,MFSD10,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,CLDND1,TTC17,AMOT,DMRT1,SLC25A1,MSX1,TEAD1,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,NCBP2,ZRANB2,MBD6,PREPL,MMP16,ZAK,ARHGAP27,SLC16A10,HRH1 |
| 3.999e-05 | -10.13 | negative regulation of transcription from RNA polymerase II promoter | biological process | GO:0000122 | 730 | 132 | 16441 | 2138 |
ATRX,BCOR,SIRT2,SKI,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,HCFC2,AEBP2,PPARG,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,SPOP,TAF9B,GZF1,PAF1,SKIL,SUPT4H1,GATA6,SUFU,CC2D1B,PER1,DLX2,ZC3H8,BEND6,BMI1,MEF2C,FOXO1,EGR1,ZHX3,SIRT7,SMAD7,HES6,BARX2,CDC73,MLX,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,NRIP1,MYB,GATAD2B,ZNF675,RREB1,PAXBP1,PRDM16,ARID5B,WWC1,PRDM1,ARID1A,NELFA,SUPT5H,TRIM37,TCF7L2,NR2F1,EHMT2,SPEN,PURB,ZFP90,NCOR1,TBL1X,N4BP2L2,ZNF254,MAP2K5,ID1,DLL4,SMARCA4,KDM1A,PPID,RNF2,SAP30,MOSPD1,ATXN1,SATB2,FGFR1,BATF3,SNCA,SMAD3,VDR,MSX2,RBBP8,ELP2,HIPK2,DNAJA3,KLF4,YEATS2,HMGA2,NCOR2,TCF3,NFX1,ID2,ATF7IP,BHLHE40,FOXO3,BMP6,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,YBX3,DMRT1,SOX6,FGF9,MSX1,MEN1,PDE2A,UBC,DKK1,MKX,RERE,NSD1,TRIB3,TBX3,BMP4,RBPJ,NR2F2,IGBP1,DDIT3 |
| 4.024e-05 | -10.12 | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_UP | 187 | 44 | 17758 | 2279 |
URB2,CAMK1,PLRG1,UBXN1,SF3A3,OPA1,SLC6A8,GIT2,TRIM66,TTC1,FARSA,NDUFV1,SHC1,SREBF2,ATXN2,BANF1,XRCC2,ACOT11,ZNF148,SSBP1,AHCYL1,RPS6KB2,ZNF629,VOPP1,GARS,MIOS,TSTA3,CDK4,FOXN3,CUX1,GPNMB,NUP214,MAK16,KDM4B,TRAP1,CUL2,CEBPZ,HIC2,SVIL,SLC4A7,COPS6,MAGI1,AP2S1,MEF2C |
| 4.070e-05 | -10.11 | Lysine degradation | KEGG pathways | hsa00310 | 52 | 18 | 6908 | 881 |
ASH1L,KMT2D,SETD1B,KMT2E,SETD2,EHMT1,PLOD1,KMT2C,SETD7,DLST,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,PHYKPL,KMT2A,TMLHE |
| 4.070e-05 | -10.11 | Lysine degradation | KEGG pathways | ko00310 | 52 | 18 | 6908 | 881 |
KMT2D,ASH1L,SETD1B,KMT2E,SETD2,EHMT1,PLOD1,SETD7,KMT2C,DLST,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,PHYKPL,KMT2A,TMLHE |
| 4.155e-05 | -10.09 | CROMER_METASTASIS_DN | MSigDB lists | CROMER_METASTASIS_DN | 80 | 24 | 17758 | 2279 |
MALL,MINK1,COL17A1,CELSR1,JUP,TRIM16,TMEM183A,PRSS3,VSNL1,C11orf80,ISG20L2,EVPL,CAV1,PHLDA2,FLNB,SH3GL1,ATP5D,FLAD1,NOP16,MBD2,CEBPZ,SVIL,ITGB4,CAV2 |
| 4.194e-05 | -10.08 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN | 193 | 45 | 17758 | 2279 |
SEC24D,DDX18,CAMK1,SLC2A1,CSNK2A1,MLH1,SLC25A44,RMI1,EIF2S2,GTF2H1,SHMT2,RAN,FXN,HMGCR,MTHFD1,RFC4,RFC3,LIMA1,NARS,ELOVL6,WDR18,ATOX1,MED27,PSMA1,TBRG4,RANGAP1,BMS1,IMPDH2,RBM28,ABCF1,CHAF1A,BATF3,STOML2,VDR,TMCO1,HPRT1,EIF2S1,UMPS,PRPF4,HMBS,EIF2B3,FIP1L1,NOLC1,DDX10,TMEM33 |
| 4.204e-05 | -10.08 | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 176 | 42 | 17758 | 2279 |
BCCIP,CTU2,PTP4A1,TTN,DNAJA4,PPARGC1B,TFIP11,MYNN,IP6K2,TGFBR2,RING1,SH2B3,PRKD3,PUS3,IKZF5,SURF2,USPL1,MYC,ZNF326,DTNBP1,JOSD1,TRMT12,ZNF3,NOM1,IFRD1,TCEB3,NOL6,UTP15,MAPK1IP1L,ZNFX1,NOP58,MAT2A,ANXA1,ZC3H12A,NAP1L5,DDX3X,ARHGAP21,SYNCRIP,DUS3L,VPS37B,SVIL,RAB30 |
| 4.228e-05 | -10.07 | JOHNSTONE_PARVB_TARGETS_3_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_UP | 410 | 81 | 17758 | 2279 |
ARHGAP26,PTP4A1,PPDPF,MPI,CDCP1,PDK4,MYH9,LPCAT3,SEC16A,FLNB,MAP2K3,VPS18,ESAM,JAG1,PMAIP1,PPFIBP1,IKBKB,PEG10,ACSL5,RBCK1,GLTSCR2,WLS,RAB7A,VIM,DSP,SLC50A1,MGST1,FGFR1,S100A16,PLIN2,SMAD3,GLS,HLA-DMA,CCDC3,AHNAK,KLF4,SYNGR2,ITGA2,AHNAK2,ABCC3,DNAH2,CLU,FAHD1,VIPR1,KLHL24,TNIK,SULT1C2,CELSR1,FN1,CDC42EP2,JUP,SUPT6H,B4GALT5,TRIO,H2AFJ,BHLHE40,TGFBR2,CMTM3,SFR1,DDIT4,NAV1,ERRFI1,FADS1,SIK3,DNMBP,ELOVL6,PPP1R21,RABAC1,SUPT5H,KLF6,ECH1,ANXA1,DYNC1H1,CAT,ATXN7,RETSAT,IRAK2,ATM,PSAP,ITGB4,NR2F2 |
| 4.228e-05 | -10.07 | HECW2 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 57520 | 289 | 66 | 16036 | 2270 |
PHF3,AMOTL1,CSNK2A1,ENAH,RADIL,RING1,PHC2,ANAPC1,ECM1,WIZ,ETF1,RNF2,KMT2A,ZC3H3,SEH1L,KAT8,WDR36,MIOS,RNMT,EIF3J,MED16,SUPT20H,MTHFD1L,DCUN1D5,RBM28,EIF3H,RAD54B,CDC16,DUS3L,LSM14A,TRMT2A,MORC2,EP400,ESCO1,FAM189B,MAP1S,NFX1,APRT,SNW1,CTNNBL1,CTR9,S100A14,PRMT5,LARP4B,TOMM34,HSD17B12,FAM120B,DDX24,LAMC1,KIAA0586,USP10,MAP7D1,NELFA,PHF6,ZRANB3,ANXA1,POP1,SRCAP,ASCC3,PXDN,KPNA1,SRBD1,L3MBTL3,SENP3,ANAPC4,ZSWIM6 |
| 4.285e-05 | -10.06 | embryo development | biological process | GO:0009790 | 943 | 164 | 16441 | 2138 |
THOC5,CUL4A,LUZP1,WDR74,NF1,MKS1,ENAH,NLE1,AMBRA1,SMARCB1,SKI,XRCC2,ANKRD11,MYH3,VPS52,ZEB1,HYAL1,FXN,PRKACB,DSC3,ZBTB17,DEAF1,FBXW4,WLS,EHMT1,COL4A3BP,SEMA3F,BRCA1,PITPNB,SUPT20H,MTHFD1L,SOX4,TCTN1,FLVCR1,KIF16B,PAF1,SKIL,EPN2,TCF7L1,BRCA2,GATA6,INSIG1,MKL2,RAD51B,SEMA3C,DLX2,RUNX1,CCNB1IP1,NRP1,MEF2C,IFT57,CHST11,CELSR1,FN1,SEC24D,PAX2,MAPK8IP3,TRIM15,ZFP36L1,ZIC2,PHGDH,TGFBR2,CDC73,SH2B3,ELL,ZNF358,EIF2S2,CEP290,COPS3,NDRG4,CTR9,MFAP2,WNT16,TERF2,MYB,MTHFD1,SETD2,RDH10,RYR2,LIG4,PRDM1,ARID1A,TPRA1,TCF7L2,KIDINS220,PALB2,HIF1A,HS2ST1,DLL4,PCNT,BIRC6,MYO7A,MYH9,PBX1,SLC39A1,KDM1A,SBDS,RPGRIP1L,CHD7,RRN3,ACD,DNAJB6,MMP14,CCDC40,RNF2,KMT2A,PRPF19,SOBP,BRD4,KMT2D,WDPCP,GRHL3,SATB2,SLC35D1,POLG2,FGFR1,SMAD3,MSX2,RBBP8,HIPK2,KLF4,MBTD1,ARL13B,ITGA2,HOXA3,IFT140,DISP1,LAMA5,HMGA2,INSIG2,ID2,LIAS,TGFB2,RNASEH2B,MBNL1,CELF1,DYNC2H1,YBX3,AMOT,SOX6,PCSK6,TOP1,TSHZ1,KDM6B,FGF9,MSX1,FGF2,FZD3,PTK2,PIK3CB,FOXC1,RPA1,DKK1,MFN2,TBX3,ATM,BMP4,APAF1,RBPJ,ITGB4,NR2F2,MMP16,STK4,KAT6A |
| 4.307e-05 | -10.05 | SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) | protein interactions | 6598 | 106 | 31 | 16036 | 2270 |
DPF3,XPC,RB1CC1,ARID2,TRA2A,SMARCAD1,DPF2,SMARCD3,SMARCA4,BRCA1,ARID1A,KMT2C,RPS6KA5,SON,ARID1B,POLR2A,SMARCB1,MLLT10,SMARCC1,MYC,COPS5,RELB,ATM,TBL1X,RUNX1,NCOR1,RAN,PRMT5,KMT2A,ZAK,CARM1 |
| 4.332e-05 | -10.05 | MGGAAGTG_V$GABP_B | MSigDB lists | MGGAAGTG_V$GABP_B | 727 | 130 | 17758 | 2279 |
CUL7,WDR74,NF1,PRKCSH,SYNJ1,CUTC,GIT2,EDC3,PCDH7,SLC30A7,AP1M1,VPS52,PRADC1,CEP135,TRIP13,PRKACB,CSGALNACT2,ZNF646,SF3A1,VPS13B,NRAS,RNMT,WDHD1,TMEM206,C1orf122,TMCO1,SOCS4,FIS1,GALNT10,TXN2,DMTF1,ZMAT3,TNRC6A,ITFG1,UBXN1,PIK3R4,CLINT1,SLC39A11,CEP164,COPS3,CTR9,TNPO3,GTF2H1,PRF1,AGL,USE1,BDNF,SIK3,CRADD,LAMC1,PRIM2,ELOVL6,XPO5,PTPN12,ZNF655,SEC31A,ITPRIPL1,SYNCRIP,PALB2,CCDC85B,PTRH2,GGT7,TCF12,FEZ2,ATP6V1A,MMRN2,ISG20L2,ST7L,RING1,PAIP2,SHC1,IKBKB,HIRIP3,ETF1,ACSL5,RFC4,RAB7A,PREX1,R3HDM1,ARL5B,STK10,UBR4,VPS53,ZFAND3,TAF2,IFT81,ELP2,ADNP,TIMM17A,WDR73,TSSC1,TRMT2A,KLHDC4,BRCC3,XRCC4,ZBTB11,BRD9,ANKS1A,PPIL3,PKIB,TMEM33,UNC13D,SSH2,HM13,ARFIP2,FOXP1,POGZ,MBNL1,TADA3,PTPN2,PEX7,POLR3D,SEC24C,ARHGAP1,CELF1,TTPAL,IL11RA,AGPAT4,PPP1R21,MFN2,NSD1,DDX50,BCAS3,SVIL,EIF2S1,ZRANB2,BMP4,DDIT3,STK4,LRRC41 |
| 4.365e-05 | -10.04 | TP53 (tumor protein p53) | protein interactions | 7157 | 942 | 176 | 16036 | 2270 |
CUL7,CUL4A,DPH1,KMT2E,ATRX,HECTD3,RCHY1,CSNK2A1,SBF2,ENAH,RNF43,NT5C3A,PRKCA,UBR5,SMARCB1,TOM1L1,SKI,RPS16,COPS4,ZNF148,ETV1,CARM1,TIMM50,LAMA4,DBN1,TNK2,LIMA1,GNL3,ANK2,HSPA5,EHMT1,AKAP12,MCL1,SHISA5,BRCA1,SOX4,TAF9B,DOT1L,DLEU1,DDX3X,TRRAP,BRCA2,INSIG1,TP53BP1,CHD3,LSM14A,COPS6,TPM1,BMI1,DMTF1,HERC2,BANP,EP400,EGR1,TAF1,SIRT7,SMAD7,PDCD5,IGF2BP3,ELL,UBE3A,EIF2S2,COPS3,MYC,GTF2H1,GTF3C3,IGF2BP1,PRMT5,PABPC1,PPA1,SERBP1,RB1CC1,POLA1,SETD2,RAP1B,USP10,ARID1A,ARIH2,MYBBP1A,RPL28,EHMT2,HIF1A,CDK9,SENP3,UMPS,NCOR1,WDR33,USP7,SART1,BIRC6,BTBD2,MYH9,SMARCA4,SAFB2,HSPA1A,KDM1A,RING1,CAD,BRE,SOCS1,DNAJB6,PPFIBP1,IKBKB,MRPS27,RNF2,FHIT,SERPINH1,KMT2A,PRMT3,TMEM200A,KAT8,RFC4,RFC3,TUBA1A,PCMT1,TOR1AIP2,VIM,SETD7,TTC28,FKBP3,UBR4,SMAD3,VDR,RANBP2,SMARCC1,HIPK2,COPS5,KLF4,CEBPZ,H2AFX,ANXA2,BRCC3,USP11,BAG1,SMG1,UTP14A,XPC,SUPT6H,AGO2,BHLHE40,CSNK1A1,FOXO3,GIGYF2,TADA3,ABL1,ADH5,SNW1,SACS,ANXA7,TRIAP1,EXOSC4,CPNE7,FBL,HNRNPM,TOP1,MSX1,TTLL5,APEX1,USP42,TPM4,APTX,PTK2,MEN1,UBE2K,KLF6,EIF5B,UBC,HSPA1B,RPA1,FBXO21,DDX50,GADD45A,SET,ATM,STK4,KAT6A |
| 4.489e-05 | -10.01 | AACTTT_UNKNOWN | MSigDB lists | AACTTT_UNKNOWN | 1782 | 283 | 17758 | 2279 |
LUZP1,TNFRSF21,PRKAB2,CACNA1H,ENAH,ADAMTS6,PCDH7,NEK6,SREBF2,LETM2,PDS5B,CHD2,CDK6,DPF3,HMBOX1,NRAS,NR6A1,ENHO,CUX1,NFIA,SEMA3F,GNAI1,SKIL,DDX3X,LUC7L3,RUNX1,FIP1L1,BMI1,MEF2C,EFNB2,TNNC1,PRPF38B,IFT57,JUP,PRPF31,SLK,NHS,DLGAP4,PID1,PDCD5,CDC73,SLC39A11,TECTA,FAM192A,CHN1,RSPRY1,EIF2S2,TSPAN2,CACNB2,MYC,IGF2BP1,CALN1,PRPS1,PABPC1,ANGPT2,BDNF,RREB1,STAG1,RB1CC1,PRDM16,RAPGEF4,RAP1B,ST6GALNAC3,IMPDH2,ARID1A,PLCB1,ONECUT2,CPT1A,MBNL2,EHBP1,USP46,NCDN,PHF6,LRP1B,PMEPA1,HIF1A,VCAN,MB21D2,COG5,HS2ST1,AMOTL1,TRERF1,BIRC6,NPAS2,ZBTB37,ACTR3,OLA1,C1QTNF7,NDUFB5,DDR2,FAM122B,PTPRG,PHC2,ZNF827,SPG21,SHC1,KDM2A,ABCA12,FMNL1,SERPINH1,MGLL,CDK12,SAP30,MALL,MPP6,EIF3J,FGFR1,HSD3B7,SNCA,TAF2,FBXL5,ZFAND3,ARHGAP21,MSX2,CAMK2D,HOXA3,LARGE,SLC4A7,TRAF3,ANKS1A,MID1,RAB30,SSH2,ZNF280C,ID2,BHLHE40,RPS6KA5,FOXO3,MBNL1,GIGYF2,ABL1,ATXN7L1,SNW1,NEBL,NLGN3,ZNF710,C15orf41,SOX6,NAV3,FGF9,PSAT1,AGPAT4,KCNMA1,ZC3H18,PTK2,KLF6,NSD1,STX1A,ARID3B,BRWD3,IPO4,DDIT3,KAT6A,UBN1,PPARGC1B,CSNK2A1,BCOR,SCAF8,SLC30A7,PCYOX1L,ZNF804A,SRSF2,PHKA1,JAZF1,ZEB1,ETV1,PRKACB,TIMM50,PTPRK,LAMA4,SESN2,TXLNG,CMIP,SIRT6,ARRDC3,SOX4,SERGEF,MGST1,C1orf122,MLLT10,GLS,TCF7L1,SUFU,TOM1L2,ARL4A,ADAM9,CSMD3,MAGI1,CHST11,FOXO1,RHOBTB1,STXBP6,PAX2,ZFP36L1,XPO7,ARID1B,DOPEY1,CEP290,HSD17B14,MSI2,TLE3,SETD2,TBXAS1,BCS1L,PRDM1,ACOXL,TCF7L2,UBE2E1,NR2F1,NAP1L5,SPAG9,TMEM182,PDE9A,TCF12,ZNF706,SNX27,CYLD,OSBPL9,PBX1,PPP2R2A,SSBP2,ARSJ,SEMA6A,JAG1,SOCS1,DUS4L,NVL,UBR1,ETF1,VCL,HN1,MAML3,KDM3B,SOBP,PTBP2,SFSWAP,GRHL3,R3HDM1,ATXN1,POU2F1,VIM,ARL5B,UBR4,ARMC4,SMAD3,ADNP,HNRNPR,SIX5,KLF4,INTS9,ZNF436,PARD3,ATXN7L2,SUPT6H,PDE4B,CLSTN2,PIP4K2A,FAM49A,IQGAP2,STC2,TMEM99,GREB1,TTC17,LDLRAD3,PCK2,HSD17B12,TOP1,ADAMTSL3,CRIM1,TEAD1,FOXN3,ABCF2,RANGAP1,PDE2A,CACNB1,SRBD1,CSRNP1,GLG1,MBD6,NR2F2,ITGB4,MMP16,MIPOL1 |
| 4.541e-05 | -10.00 | DEAD/DEAH_box_helicase_dom | interpro domains | IPR011545 | 66 | 21 | 18293 | 2341 |
SKIV2L,DDX28,DDX41,DDX24,SKIV2L2,DDX18,HFM1,DDX19A,EIF4A2,DDX60,DDX60L,DDX49,DHX57,DDX3X,ASCC3,DDX56,DDX50,DHX37,DHX33,DDX31,DDX10 |
| 4.569e-05 | -9.99 | human chr10q25.2 | chromosome location | human chr10q25.2 | 12 | 7 | 26250 | 2590 |
ACSL5,BBIP1,RBM20,GPAM,ZDHHC6,VTI1A,LOC103344931 |
| 4.617e-05 | -9.98 | SHEN_SMARCA2_TARGETS_UP | MSigDB lists | SHEN_SMARCA2_TARGETS_UP | 411 | 81 | 17758 | 2279 |
FAM208B,PHF3,CUL4A,FEM1C,SUCLG1,NF1,ATRX,PAFAH1B1,ACTR3,HLTF,GYG1,PIBF1,SCAF8,EXOC1,PRKD3,COPS4,NUP133,ATG3,ZDHHC6,SOCS6,SUCLG2,HIBCH,KDM3B,TFCP2,RAB7A,TSN,PCMT1,ATXN1,SON,TAF9B,OSBPL1A,FBXL5,HSDL2,LSM14A,LUC7L3,MKL2,BBIP1,RNF130,TROVE2,COMMD10,HERC2,PRPF38B,INSIG2,ITFG1,ANKRD17,SLK,DPF2,VPS45,SLC25A12,MLH1,IKBKAP,CLINT1,PSMF1,ANXA7,DCTN4,TANK,CTR9,RDX,UPF2,GTF3C3,AKAP11,WDR61,STAG1,WDFY3,TMEM126B,ANKMY2,RSBN1,RPA1,VPS13C,BAZ2B,KIDINS220,SERINC1,KIAA0355,HNRNPH3,CUL2,RIOK3,NCOR1,RBPJ,PREPL,SRP14,RNF114 |
| 4.647e-05 | -9.98 | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | MSigDB lists | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | 300 | 63 | 17758 | 2279 |
HERC2,MYCBP2,NOMO3,ADAM19,LIN28B,LUZP1,GPBP1L1,ATRX,PAFAH1B1,RFX1,TRIO,SMAD7,KLHL18,MYH9,NECAP1,SYNJ1,ARID1B,IQGAP2,PRKCE,RNF141,RGS17,NRF1,SLX4,PDZD2,HAS3,SYN2,GLYR1,SLC38A2,PDS5B,JOSD1,LYST,GATAD2B,SOBP,PCGF3,ADAMTSL3,SSFA2,BAZ2A,POLK,TEAD1,ARRDC3,ZNF512B,NFIA,RAP1B,MCL1,RSBN1,FAM126B,MEF2D,SOX4,ARRDC4,BSN,DDX3X,FAM135A,BAZ2B,GATA6,INSIG1,LMBR1L,DSC2,KLF4,TECPR2,CSMD3,TRAF3,SH3PXD2A,MAP2K4 |
| 4.647e-05 | -9.98 | CAGTGTT,MIR-141,MIR-200A | MSigDB lists | CAGTGTT,MIR-141,MIR-200A | 300 | 63 | 17758 | 2279 |
TCF12,PTP4A1,SNX27,RBM33,ATP6V1A,SUPT6H,MED13L,KLHL18,PPP2R2A,CSNK2A1,WDR26,IGF2BP2,BHLHE40,TGFB2,PTPRG,CSNK1A1,FOXP1,MBNL1,SLC1A1,SEMA6A,NAMPT,PDZD2,UBE3A,IKZF5,JAZF1,PDS5B,ERRFI1,PRKACB,TOP1,SOBP,PCGF3,CHD9,WDFY3,FOXN3,TTYH2,PCNXL2,ATAT1,LRRC8A,ATXN1,MAP7D1,CAMSAP2,PITPNB,LENG8,SON,SLC23A2,YTHDF2,ATXN7,SPAG9,GATA6,SERF2,GPC2,KPNA3,LUC7L3,ARNTL,HIC2,FKBP5,NFASC,TAF12,RUNX1,NRP1,MMP16,MAP2K4,LPP |
| 4.674e-05 | -9.97 | TGCCTTA,MIR-124A | MSigDB lists | TGCCTTA,MIR-124A | 532 | 100 | 17758 | 2279 |
ZNF706,CGN,LIN28B,RBM33,CELSR3,SLC48A1,TMEM109,MYH9,LPCAT3,TUBB6,LCLAT1,GIT2,SEMA6A,LPIN1,ZNF608,ANKRD13A,PDZD2,JAG1,JAZF1,NCKIPSD,SUCLG2,ETF1,ZNF148,ETV1,ZNF3,CDK6,ZCCHC14,ANTXR2,BRD4,PTBP2,ABCC4,OSBP2,VSNL1,PNN,COTL1,SERP1,RAB10,BTBD11,GZF1,EPN2,AHNAK,DNAJC1,KLF4,ABHD3,SLC4A7,RPS6KB1,NFASC,YEATS2,LPP,KLHL24,EFNB2,RFX1,SESTD1,TCF3,PID1,MYNN,ATF7IP,AKT1S1,BMP6,SLC25A20,SH2B3,NAV1,ANXA7,CACNB2,DCTN4,ANXA5,GLTP,LARP4B,DMRT1,PCSK6,NAV3,PEA15,PDE4A,RREB1,LAMC1,WDFY3,SIGMAR1,MYO10,TEAD1,SMARCAD1,ZBED4,PTPN12,FERMT2,RYR2,PALLD,PDE2A,PHF6,RERE,OXSR1,TPD52L2,BAZ2B,PMEPA1,LEMD3,VPS37B,SLC16A1,ZRANB2,FNBP1L,MAP2K4,LMBRD2,STK4 |
| 4.676e-05 | -9.97 | rev (p19) | protein interactions | 155908 | 301 | 68 | 16036 | 2270 |
CUL4A,PLRG1,NAT10,PPP2R2A,PLOD1,CSNK2A1,TUBB6,SPATS2,PRKCA,HNRNPA3,SRSF2,DNAJB6,SSBP1,RAN,TRIP13,SF3A1,PRPF19,WDR36,TUBA1A,NARS,ITPA,SKIV2L2,HIST1H2BL,NUP214,UBR4,DDX3X,RANBP2,EPN2,HNRNPR,FUS,PDCD11,PRPF31,KHDRBS1,H2AFJ,SF3A3,IGF2BP2,POM121,SUB1,DDX56,EIF2S2,TNPO3,IGF2BP1,ANP32B,PABPC1,HNRNPM,SPTAN1,DDX24,APEX1,PAXBP1,PSPC1,PACS1,RANGAP1,NOP58,ABCF1,UBC,DYNC1H1,TOE1,KPNA1,MYBBP1A,SYNCRIP,SRBD1,HNRNPH3,SET,HK2,PURB,GPN1,ATM,GPATCH4 |
| 4.687e-05 | -9.97 | HIST1H3A (histone cluster 1, H3a) | protein interactions | 8350 | 182 | 46 | 16036 | 2270 |
ASH1L,ESCO1,CUL4A,TAF1,ATRX,SIRT7,SMARCA4,SIRT2,PRKCA,PELP1,CDC73,KDM1A,CTR9,ANP32B,PRMT5,KMT2A,CARM1,KDM6B,GATAD2B,KAT8,BRD4,WDR61,SETD1B,EHMT1,SETD2,ATXN1,WWC1,HDAC8,MED16,SETD7,KMT2C,MEN1,CHAF1A,PAF1,PALB2,EHMT2,TP53BP1,CHD3,SET,BCAS3,RAD51B,H2AFX,NCOR1,IPO4,KDM4C,KAT6A |
| 4.722e-05 | -9.96 | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN | MSigDB lists | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN | 160 | 39 | 17758 | 2279 |
IFT57,PAPD4,DDX18,DBF4,SMARCA4,IP6K2,RSF1,C11orf54,ACD,ANAPC10,PAK1IP1,RNF111,DDX31,SSBP1,RAN,MET,C15orf41,TIMM50,TSHZ1,WDR61,SLC38A1,TMEM126A,NOL8,MINA,MCM2,PPIP5K2,DKC1,DENND4A,PEX1,GEMIN5,TAF2,IREB2,LEMD3,LRRC40,ORC5,ABHD3,SLC16A1,TATDN1,GCSH |
| 4.756e-05 | -9.95 | WHEP-TRS | smart domains | SM00991 | 5 | 5 | 9131 | 1249 |
MARS,EPRS,GARS,HARS,WARS |
| 4.837e-05 | -9.94 | CDK9 (cyclin-dependent kinase 9) | protein interactions | 1025 | 177 | 45 | 16036 | 2270 |
RCHY1,IGF2BP2,HLTF,UBR5,HSPA1A,CDC73,ZC3H13,RNF40,ELL,SNW1,MYC,MRPS27,ATRIP,IGF2BP1,SERPINH1,KMT2A,CDK12,TERF2,CDC37,SKIV2L,PMS1,RFC4,BRD4,SETD1B,HSPA5,MARS,BRCA1,SUPT5H,FGFR1,POLR2A,SMAD3,PAF1,OXSR1,SEC31A,SRCAP,SYNCRIP,GATA6,ARID3B,CCNT1,TRAP1,HNRNPR,CDK9,ATM,FKBP5,ANXA2 |
| 4.839e-05 | -9.94 | WANG_CLIM2_TARGETS_DN | MSigDB lists | WANG_CLIM2_TARGETS_DN | 177 | 42 | 17758 | 2279 |
ZNF292,MED13L,RCHY1,COBLL1,MYNN,SLC25A44,MBNL1,PPP1R9A,MRPS11,RPP30,FARSA,ELL,IDI1,JAG1,GPR87,NT5C,NAA35,C15orf41,SF3A1,IFRD1,PRIM2,TFPI,TCEB3,METTL15,ATG12,ZNF91,SRA1,ISG15,PEX1,RDH11,CAMK2D,DNTTIP1,RARS,RAD18,COPS5,CEBPZ,PAM,CSRNP1,ARHGAP12,ASB3,NCOR1,TATDN1 |
| 4.888e-05 | -9.93 | zinc ion binding | molecular function | GO:0008270 | 1151 | 196 | 16491 | 2164 |
ADAM19,MYCBP2,PHF3,TRIM16,KMT2E,ATRX,POLR1A,RCHY1,RNF43,ADAMTS6,HLTF,SIRT2,PRKCA,BIRC2,UBR5,SKI,MMP7,ZFHX3,LONRF2,ANAPC11,ZEB1,RNF111,KDM5C,HRG,ZNRD1,ZNF3,ZMYM2,TRIM14,DPF3,DTNB,TRIM13,RBCK1,ZNF195,SIRT6,PPARG,LIMA1,BAZ2A,NR6A1,LVRN,EHMT1,MSRB3,BRCA1,ZDHHC14,KMT2C,ZNF91,MLLT10,ZNF622,RBSN,SUPT4H1,ZGRF1,RAD18,GATA6,SH3RF1,CHD3,NSMCE1,ADAM9,CCNB1IP1,BMI1,ZNF598,RNF214,ZMAT3,LPP,HERC2,TRIP6,ZCCHC8,SEC24D,DPF2,MEX3A,TRIM15,RSF1,C11orf54,RLF,TIMM10,CHD5,RSPRY1,RNF40,RNF141,RBM20,RNFT2,ALKBH8,CNOT4,LRSAM1,ZCCHC7,SCAF11,ZNF675,GATAD2B,TIMM8B,USP49,MEX3B,TRIM37,MTR,ARIH2,PHF6,NR2F1,PDLIM1,EHMT2,ZZEF1,ZCCHC6,DPEP1,PDLIM5,ZFHX2,RNF114,MPI,CYLD,ASH1L,LIN28B,GTF2H2C,RPS29,RNF24,ZMAT2,EEA1,RING1,TRIM66,PHC2,CAD,ZSWIM7,KDM2A,UBR1,ZDHHC6,MMP14,INTS12,RNF2,TTC3,ZFP37,PEG10,KMT2A,SEC24A,ZCCHC14,PCGF3,KMT2D,DDX41,ADAM32,MARCH6,CA5B,UBR4,SNCA,VDR,TAF2,ZFAND3,SMAD3,BAZ1A,RANBP2,KDM4B,ALAD,KLF4,NSMCE2,MBTD1,PAM,TRAF3,RNF130,FUS,MID1,TRIM36,MORC2,DBF4,NFX1,SF3A3,MYNN,TRIM22,ZNF346,ADH5,SUV39H2,TAF3,SEC24C,PMPCA,LTN1,PRICKLE2,FBXL19,MICAL3,MARCH9,PXN,ADAMTSL3,KDM5B,ZFYVE1,KDM5A,ZMYM5,TOP3A,ZNF407,NAPEPLD,ZRANB3,RERE,NSD1,BAZ2B,ZDHHC11,ADAT2,ZNF330,AGTPBP1,RNF138,FNTB,USP20,ZRANB2,NR2F2,MMP16,KDM4C,ZSWIM6,KAT6A |
| 4.981e-05 | -9.91 | Fatty acid, triacylglycerol, and ketone body metabolism | REACTOME pathways | R-HSA-535734 | 212 | 50 | 8202 | 1117 |
NCOR2,NPAS2,PRKAB2,TNFRSF21,PPARGC1B,GPAT3,MED13L,MED18,LCLAT1,LPIN1,SLC25A20,DECR1,NRF1,SREBF2,LPIN2,ACOT11,MED24,ME1,LPCAT1,HSD17B12,CARM1,SLC25A1,FDFT1,HMGCR,ACSL5,MCEE,ACADS,FADS1,CHD9,PPARG,TEAD1,ELOVL6,PCCA,AGPAT4,MED27,SMARCD3,MED16,CPT1A,ANGPTL4,MMAA,PLIN2,TRIB3,ACOX1,ARNTL,MED15,BDH2,TBL1X,NCOR1,GPAM,MED20 |
| 5.017e-05 | -9.90 | TGGTGCT,MIR-29A,MIR-29B,MIR-29C | MSigDB lists | TGGTGCT,MIR-29A,MIR-29B,MIR-29C | 488 | 93 | 17758 | 2279 |
PTP4A1,ADAM19,DNM3,LUZP1,BIRC6,PRKAB2,TMEM183A,SBF2,ADAMTS6,CORO6,TMEM132A,EDC3,PAIP2,SKI,KDM2A,SOCS1,JOSD1,KDM5C,CMPK1,CDK6,PCGF3,BRD4,COL5A2,ATG9A,ENHO,GPCPD1,ARRDC3,NFIA,GMFB,ATXN1,AKAP13,MAT2A,HTR7,DDX3X,SLC30A3,SMARCC1,INSIG1,PER1,KLF4,TNFRSF1A,GREB1L,NFASC,TPM1,VASH2,BLMH,RAB30,NCOR2,SESTD1,ZFP36L1,WDR26,ZNF346,RLF,NAV1,HAS3,LDOC1L,NDRG4,KDELC1,PRICKLE2,RAPGEFL1,NLGN3,MFAP2,LARP4B,AMOT,CAV2,NAV3,SPTAN1,HMGCR,CLK2,LAMC1,WDFY3,AGPAT4,KCNMA1,XPO5,USP42,ZNF512B,TTYH2,RAP1GDS1,FERMT2,MEX3B,FAM126B,ARRDC4,TRIM37,ATAD5,IREB2,STX1A,KIAA0355,SPEN,RNF138,SNX24,SLC16A1,GPAM,BRWD3,SH3PXD2A |
| 5.051e-05 | -9.89 | ENO1 (enolase 1, (alpha)) | protein interactions | 2023 | 274 | 63 | 16036 | 2270 |
INSIG2,CUL7,MVK,MAP2K5,CUL4A,FN1,POLR1A,HSD17B10,FARS2,LETMD1,BHLHE40,XPO7,AARS,POGZ,SCAF8,HIST2H2AB,NOP56,FKBP1A,PPFIBP1,RDX,UPF2,POLE3,FBL,YARS,HNRNPM,NUDC,NIPSNAP1,SF3A1,PRPF19,FLNC,TXLNG,ITPA,POLA1,PCMT1,LDHA,LIG4,SUMO3,ZNFX1,BRCA1,PITPNB,SUPT5H,C8orf33,CYB5B,CPT1A,MBNL2,STK10,ISG15,ANXA1,CAT,ASCC3,NME1-NME2,UBAP1,TP53BP1,CHD3,LUC7L3,E2F4,AGTPBP1,HNRNPH3,COPS5,CUL2,H2AFX,FUS,IPO4 |
| 5.077e-05 | -9.89 | LARP7 (La ribonucleoprotein domain family, member 7) | protein interactions | 51574 | 48 | 18 | 16036 | 2270 |
NIFK,LIN28B,SIRT6,TRA2A,SIRT7,CSNK2A1,JMJD6,SPAG9,RPS16,CCNT1,HNRNPR,CDK9,RNF2,ZC3H8,FBL,BRCC3,ZC3H3,TERF2 |
| 5.078e-05 | -9.89 | pharynx | COSMIC cancer mutations | pharynx | 2803 | 424 | 17775 | 2278 |
ARHGAP26,ZNF292,MYCBP2,THOC5,DPH1,CACNA1H,TUBE1,HMOX2,PRKCA,NUP160,SYNJ1,LPAR3,UBR5,PDZD2,SREBF2,ZFHX3,FAAH2,PDS5B,RNF111,KDM5C,TBC1D8,ACADS,NRAS,LIMA1,PTPRM,ALDH1L2,NFIA,CUX1,EFHC1,PLEKHM3,MCM2,DENND4A,DOT1L,DDX3X,AHNAK,BRCA2,TRRAP,VPS13D,DNAH2,RIOK1,TNFRSF10D,WDR66,ZNF532,SYNPO,LPP,MEF2C,HERC2,EP400,DROSHA,CELSR1,ANKRD17,ZHX3,LARS2,KHDRBS1,SIRT7,PRAF2,DLGAP4,PID1,DPM3,RSF1,TGFBR2,CHD5,SH2B3,PRKCE,NAV1,ENTPD5,SCAF1,PIGG,SLC16A9,GTF3C3,CALN1,PRMT5,PRPS1,FMNL2,SERBP1,LRRC20,GATAD2B,SCAF11,USE1,RREB1,POLA1,RAP1GAP2,KIAA0586,RYR2,ATAT1,IMPDH2,ARID1A,EHBP1,SLC26A11,ZNF655,ZNF783,DYNC1H1,ZNF425,VPS13C,LRP1B,KIDINS220,GTF2A1,NME7,UBAP1,VCAN,SPEN,ZZEF1,NCOR1,IQSEC2,DHCR7,SRP14,MAP2K4,RTTN,SPRED2,RAB11FIP4,ABCA3,TRPM2,DDX18,ATP6V1A,URB2,MYH9,PTPRG,HNRNPA3,STAM,IGSF1,ZNF827,SLX4,TMEM184A,ASNS,ZSWIM7,NBEA,CEP63,MSH4,ZC3H3,LYST,PMS1,MPP6,KMT2D,BRD4,SLCO6A1,LGALS1,FAM171A2,LRRC8A,PCNXL2,MEF2D,TTC28,DSP,ERC1,MAT2A,FGFR1,DHX57,BAZ1A,IQCH,SMARCC1,YIPF2,ASTN2,HIPK2,POLR3E,WDR7,LARGE,RPS6KB1,TRAF3,CENPBD1,MDN1,NOLC1,LAMA5,METTL2B,MID1,MAPT,TRIM36,LRCH1,NCOR2,BRAF,B4GALT5,TCF3,TRAK1,C1orf226,SF3A3,KIF5C,MLH1,FOXO3,POM121,NEDD4,ABL1,ATXN7L1,NPRL2,GATC,UNC13A,NISCH,LTN1,HARS2,ARHGAP1,DYNC2H1,SAMD4A,PNMA1,SPTAN1,PFKFB4,FER1L5,FAM98A,PXN,TTLL5,WDFY3,ZFYVE1,ZC4H2,FAM126B,PDE3B,MMAA,UBC,ETFDH,NSD1,SRCAP,PXDN,ZNF155,IREB2,STX1A,HERC1,ORC5,ATM,SVIL,MYOM2,NDUFS5,SORCS2,KDM4C,LRRC41,PHF3,FEM1C,RBM33,UBN1,ATRX,NF1,POLR1A,FANCD2,TRPM6,ANKRD18A,BCOR,TMEM132A,SEC16A,COX10,CUTC,SCAF8,SNAPC4,SMARCB1,DST,SLC39A7,ANKRD11,MYH3,ZEB1,TMPO,ZBTB17,DSC3,FLNC,ZNF124,BAZ2A,ZNF414,ANK2,GDPD1,VWCE,LAMA2,KMT2C,KCNH2,CRYBG3,PEX1,YTHDF2,BSN,ZNF622,INSIG1,HLCS,TP53BP1,CHD3,TNFRSF1A,CTAGE5,CSMD3,GALNT10,CLU,RNF214,TMEM158,DCAF5,MTCH1,USP15,SEPHS2,SARS,STX8,FN1,LRRC28,CLK1,STXBP6,PRSS3,HSD17B10,MED13L,SMG7,EVPL,QSER1,DNAH1,RHBDD1,CEP164,CEP290,SAMD11,CTR9,SYNJ2,ZCCHC7,AKAP11,N4BP2,CPSF3L,ZNF629,CAMKK2,LAMC1,PPAT,ELP3,SETD2,HAUS6,JMJD1C,OBSCN,LIG4,CORIN,ISG15,PRPF40B,UBAP2,BICD1,FAM135A,FAT1,DNAH17,SDCCAG8,RRAGA,ZNF430,CASS4,SH3PXD2A,PDE9A,DMXL2,SART1,ASH1L,OLFM2,PCNT,ARID2,CELSR3,PSTPIP2,GPR143,MYO7A,SMARCA4,COBLL1,PBX1,TMEM177,ZNF83,SLC9B2,PIBF1,TNKS1BP1,PPP1R9A,SEMA6A,GBF1,KDM1A,SBDS,ZSCAN5A,ZC3H13,CAD,ZFP37,AKNAD1,MET,VCL,TMEM14C,TMEM200A,ACSL5,SEC24A,METTL2A,GRHL3,ATXN1,VIM,AKAP13,NHSL1,ATP8B2,UBR4,TMEM186,RAD54B,WARS,SMAD3,ARMC4,RANBP2,HYAL3,KPNA3,ZNF557,ATG7,INTS9,TMEM101,RNF130,MED20,HEATR1,SMG1,DNAJC2,SUPT6H,PDE4B,CLSTN2,PPHLN1,SOGA1,FOXP1,ANKRD54,SFI1,SACS,SEC24C,IFIT5,DCTN4,DDX31,CD44,TTC17,ADAMTSL3,KDM5A,FOXN3,PSPC1,PPP1R21,TEX14,FERMT2,MEN1,LENG8,ZNF407,EIF5B,NAALADL2,TMEM175,RERE,MKX,CTIF,ZNF221,TBX3,FNTB,DNAJC12,TAF12,NFKBIB,POLR1C,ITGB4,RPS6KC1,MMP16,LMBRD2,ZSWIM6 |
| 5.082e-05 | -9.89 | V$AHRARNT_01 | MSigDB lists | V$AHRARNT_01 | 133 | 34 | 17758 | 2279 |
DLL4,PAX2,IP6K2,MBNL1,STAM,JAG1,SHC1,JAZF1,STC2,TNPO3,NLGN3,SRRM2,ZMYM2,CDK6,PABPC1,SOBP,BDNF,SESN2,EIF4A2,MEX3B,SOX4,ONECUT2,TCF7L2,CAMK2D,GTF2A1,LUC7L3,SPEN,HK2,ADAM9,RUNX1,ANKS1A,XPO6,SPOCK2,ATXN7L2 |
| 5.105e-05 | -9.88 | adrenal_gland | COSMIC cancer mutations | adrenal_gland | 2723 | 413 | 17775 | 2278 |
MYCBP2,CDCP1,CACNA1H,HLTF,NBEAL1,LRP5L,LPAR3,LPIN1,CIAPIN1,PABPC4,MGA,PCDH7,GIPR,PDZD2,SREBF2,IKZF5,PDS5B,VPS52,KDM5C,SRRM2,ZNF646,NRAS,PTPRM,EHMT1,KIF15,WDHD1,SEMA3F,ZDHHC14,DDX60,RBM28,SAP30BP,MAK16,PLCXD2,GZF1,PYCR1,OSBPL1A,STOML2,AHNAK,TRRAP,LSM14A,CCNT1,VPS13D,SEMA3C,DNAH2,GREB1L,CCNB1IP1,WDR66,ZNF598,SPOCK3,PTPN14,HERC2,PRPF38B,ANKRD17,ZHX3,ST6GAL1,SIRT7,TRIO,DPM3,PRPF39,TGFBR2,CDC73,CD226,ABCA7,ANXA10,MTUS1,RBM20,ENTPD5,DHX37,KIAA1671,NOVA2,ALKBH8,MED24,CAV2,MYB,SCAF11,SIK3,COL17A1,ALG6,RREB1,MYO10,RDH10,RYR2,PTPN12,ARID1A,EVI5,USP46,ANGPTL4,ABCF1,NCDN,DYNC1H1,ZNF425,ASCC3,VPS13C,LRP1B,MTHFD2,KPNA1,KIDINS220,PDLIM1,EHMT2,TRAP1,PMEPA1,VCAN,MED15,D2HGDH,ZCCHC6,PEX13,CNOT6,KIAA0196,MACROD1,WDR33,DHCR7,ARHGAP10,ZFHX2,SYT17,DNM3,BIRC6,HFM1,C1QTNF7,MYH9,PTPRG,FOSL2,TRIM66,RPGRIP1L,PDE3A,NOP56,TERF2IP,SLX4,ABCA12,GLYR1,LPIN2,MRPS27,C16orf58,NBEA,TTC3,KMT2A,CDK12,CASP8AP2,LYST,ZCCHC14,RFC4,KMT2D,GON4L,PCNXL2,ATP6V0A1,GNL1,MARCH6,GSTCD,DSP,STK10,FGFR1,DCBLD2,GNG2,DNTTIP1,KDM4B,PAM,IFT140,TRAF3,LAMA5,BRAF,XPC,SESTD1,ZNF280C,NFX1,FARS2,KIF5C,RTN4,AKT1S1,MLH1,MON2,GDPD5,RSRC1,GIGYF2,FAM8A1,TMCO6,ABL1,ZNF239,ZNF483,SUV39H2,CFDP1,LTN1,HARS2,LARP4B,FBXL19,SOX6,DIS3L2,FAM120B,DDHD1,TSHZ1,C19orf43,OASL,PPIP5K2,ECH1,UBC,CCDC150,INF2,NSD1,RETSAT,SRCAP,ZNF155,HERC1,ATM,SLCO5A1,SVIL,PTPN4,MYOM2,MTMR1,CYP24A1,CUL7,FEM1C,RBM33,ATRX,NF1,GPBP1L1,KIF5A,POLR1A,PPARGC1B,TRPM6,ZNF107,PLOD1,RNF43,BCOR,FAM13A,TMEM132A,COX10,BIRC2,SNAPC4,FRRS1,SMARCB1,DHX33,YLPM1,MARVELD2,NCKIPSD,ANAPC11,ANKRD11,MYH3,GPATCH1,ZEB1,HYAL1,RAN,NDUFA6,ZMYM2,PTPRK,FAM184A,DSC3,FMNL3,CHD9,SLC3A2,MIOS,ZNF195,ABCC4,BAZ2A,ANK2,GDPD1,VWCE,HDAC8,MTHFD1L,KMT2C,SERGEF,KIF16B,TAF9B,CHAF1A,TCF7L1,GATA6,TRMT5,TP53BP1,CC2D1B,RLTPR,SGSM2,EME1,DCTN3,SEC24D,ZCCHC8,TAF1,ALG8,EVPL,XPO7,DNAH1,CMTM3,DOPEY1,KIAA1958,ELL,SIPA1L3,MCAM,ZNF354A,CEP290,CTR9,PRF1,ATP6V0D1,AKAP11,HSD17B14,ZNF629,RANBP6,CAMKK2,OBSCN,ZNFX1,PRDM1,ANKRD20A4,DNAH14,EXOC6,TBC1D2,MGAT2,NAP1L5,GRIK4,SYCP2L,UBAP2,ITPRIPL1,PALB2,KIAA0355,FAT1,DNAH17,EXOC4,HK2,PPP1R12B,DTD1,ZFP90,PDE9A,ZBTB24,NR2C2AP,BCCIP,ASH1L,ARID2,LPCAT2,SMARCA4,SPATS2,SLC9B2,PIBF1,TNKS1BP1,PPP1R9A,SEMA6A,GBF1,DHX35,ZNF121,FDX1,SBDS,ZSCAN5A,CAD,VPS18,GRIN2C,PPFIBP1,BCAP29,MYH15,ZFP37,AKNAD1,MET,ITGAX,CTC1,SEC24A,SOBP,KDM3B,ANKRD33B,CPOX,POU2F1,VIM,EDEM2,NHSL1,ENC1,NUP214,UBR4,WARS,IFT81,DUS3L,ADNP,ARNTL,INTS9,PRRT3,NFRKB,HEATR1,PUS1,USP11,SMG1,ZNF507,DNAJC2,AUH,SH2D3A,MAP3K13,DBF4,CLSTN2,C14orf159,WDR26,SEMA3E,ENOX1,FOXP1,ANKRD54,NDUFV1,GART,SEC24C,IFIT5,TANK,STC2,PRICKLE2,FBL,PCK2,DNMBP,MON1A,PSMC3IP,ABCF2,PPP1R21,MARS,ARHGAP32,PDE2A,MEN1,ZNF407,EIF5B,NEU1,RERE,SRBD1,GPC2,GADD45A,MPP7,BCAS3,MSH3,RWDD2B,ITGB4 |
| 5.138e-05 | -9.88 | CCDC8 (coiled-coil domain containing 8) | protein interactions | 83987 | 544 | 110 | 16036 | 2270 |
CGN,SART1,MYCBP2,CUL7,PCNT,EIF3C,ACTG1,NF1,POLR1A,DDX19A,AARS2,TUBB6,PRKCA,SEC16A,UBR5,EEA1,PPP1R9A,PABPC4,FLNB,NOP56,DST,SRPRB,CAD,ZBTB21,SERPINH1,TRIP13,TIMM50,TMPO,PHLDB2,SLC3A2,RFC3,SSFA2,LIMA1,HSPA5,MCM2,DSP,STOML2,CXADR,BAZ1A,DDX3X,RANBP2,AHNAK,HNRNPR,CHD3,ADNP,LRRC40,HEATR1,ANXA2,MDN1,NRP1,PDCD11,BLMH,CEP170,HERC2,EP400,MCM6,JUP,SCAMP3,KHDRBS1,IGF2BP2,VARS,SOGA1,IKBKAP,XPO7,PHGDH,GIGYF2,IGF2BP3,SACS,GART,KIAA1671,CEP290,MCM5,DSG2,ZNF326,MFAP2,IGF2BP1,FBL,AMOT,PABPC1,MTHFD1,LAMC1,RB1CC1,ABCF2,ZNF512B,LDHA,MARS,NOP58,ABCF1,FOXC1,NCDN,POLR2A,UBC,SMPDL3B,RPA1,CAT,DYNC1H1,RARS,ASCC3,EPRS,DDX50,MYBBP1A,SYNCRIP,RPL28,NSF,TRAP1,SNAP23,HNRNPH3,EIF2S1,SVIL,PGAM5 |
| 5.161e-05 | -9.87 | GTGCCTT,MIR-506 | MSigDB lists | GTGCCTT,MIR-506 | 690 | 124 | 17758 | 2279 |
CGN,ADAM19,DLL4,RAB11FIP4,RBM33,UBN1,PAFAH1B1,TMEM109,MYH9,ENAH,TMEM104,FAM122B,SLC29A1,LCLAT1,GABPB2,SEMA6A,TOM1L1,SLC30A7,SKI,JAG1,SHC1,CMPK1,ANTXR2,NRAS,PTBP2,ABCC4,MANBAL,GMFB,VIM,CAV1,ARL5B,SERP1,RAB10,MAT2A,KIF16B,GNAI1,RHOU,DDX3X,ZFAND3,SLC7A1,GATA6,KPNA3,DNAJC1,CC2D1B,SH3RF1,TECPR2,PAM,GALNT10,DLX2,NRP1,ZBTB11,YEATS2,DCAF5,SPOCK2,LPP,KLHL24,TMEM63C,PRPF38B,SSH2,AK2,SESTD1,RFX1,UBXN1,PDE4B,ZFP36L1,RCAN1,ATF7IP,AKT1S1,SPIRE1,IQGAP2,RNF141,SH2B3,KIAA1958,NAV1,UBE3A,NEBL,CLDND1,IGF2BP1,AMOT,DMRT1,PRPS1,TOMM34,FMNL2,SLC25A1,TSHZ1,LAMC1,RREB1,WDFY3,RB1CC1,MYO10,TEAD1,SMARCAD1,RDH10,ARID5B,ZBED4,XPO5,PTPN12,RYR2,NXN,PALLD,PLCB1,EVI5,MTR,PHF6,MKX,NAP1L5,TPD52L2,TRIB3,UBAP2,LEMD3,VCAN,VPS37B,SLCO5A1,SVIL,SLC16A1,TMEM117,ZRANB2,GPAM,SH3PXD2A,MAP2K4,C7orf26,CTXN1,STK4,RNF114 |
| 5.171e-05 | -9.87 | SHMT2 (serine hydroxymethyltransferase 2 (mitochondrial)) | protein interactions | 6472 | 427 | 90 | 16036 | 2270 |
TCF12,ZNF76,CUL7,AMOTL1,TRERF1,CCDC58,ATP6V1A,NPAS2,POLR1A,MKS1,FAM210A,PIBF1,SCAF8,RPGRIP1L,NOP56,DECR1,BRE,RABGAP1L,YARS,GDAP1,ATF4,DDX41,AKAP8L,LIMA1,ITPA,NOL8,HSPA5,METTL2A,NR2F1-AS1,MEF2D,C10orf76,DKC1,CA5B,FOXRED1,TBC1D16,SAP30BP,UBR4,STK10,PUM3,ELP2,TP53BP1,CHD3,LUC7L3,CAMKMT,ATG7,CRCP,BBIP1,KLHDC4,BRCC3,CADM4,PIGN,TRIP6,SEC24D,PPHLN1,NFX1,FARS2,JMJD6,CEP164,TTLL11,USPL1,WDR27,UNC13A,SHMT2,HARS2,RAPGEFL1,ALDH18A1,HNRNPM,NIPSNAP1,PXN,DDX24,WDFY3,POLA1,AOC2,WDR18,ABCF2,MRPS10,ZNFX1,BMS1,ARID1A,SUPT5H,SEC31A,GTF2A1,UBAP1,ZBTB8OS,KIAA0754,CUL2,APAF1,FNBP1L,GPATCH11,KDM4C |
| 5.248e-05 | -9.86 | MORF_PRKAG1 | MSigDB lists | MORF_PRKAG1 | 212 | 48 | 17758 | 2279 |
NCOR2,SARS,DDX18,FAM189B,ANKRD17,PRKCSH,KHDRBS1,CSNK2A1,RTN4,VARS,HLTF,XPO7,PARN,TERF2IP,CAD,ANXA7,ATXN2,AHCYL1,TOMM34,MPST,NIPSNAP1,KDM3B,TSTA3,LSM12,PARP2,SFSWAP,BMS1,MARS,RABAC1,EHBP1,SERP1,ARIH2,POLR2A,MFN2,YIF1A,SEC31A,PWP1,EPRS,TP53BP1,CHD3,COQ9,GLG1,SLC25A11,NCBP2,NFRKB,SCARB1,COPS6,XPO6 |
| 5.276e-05 | -9.85 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | 189 | 44 | 17758 | 2279 |
YDJC,IMMP2L,RWDD1,FOXO1,WDR74,MRI1,PDE4B,IGF2BP2,GDPD5,URB1,PIP4K2A,YARS2,HDDC2,DENR,CD96,ENTPD5,THADA,RABGAP1L,MYC,PPIL2,RELB,ZEB1,GEMIN4,TSPAN14,MCEE,DNMBP,PDK1,GLTSCR2,ZFYVE1,PCCA,DKC1,PDE2A,MTR,SLC26A11,SKIL,TSR1,FBXO21,MYBBP1A,HSDL2,PDLIM1,POLR3E,DTD1,TBL1X,PFDN2 |
| 5.276e-05 | -9.85 | GSE17721_0.5H_VS_8H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDM_UP | 189 | 44 | 17758 | 2279 |
ZNF706,LETM1,FN1,SUCLG1,DDX18,PPARGC1B,RARS2,CERS5,CD99L2,CHCHD10,SSBP2,TGFBR2,FOXO3,REEP5,ZFHX3,ATG3,NDRG4,CORO1A,MAP3K14,SLC35C2,ATP6V0D1,PABPC1,MTHFD1,SRPK2,MCEE,VOPP1,WBSCR22,LDHA,NXN,TTYH2,TPRA1,ODC1,RPA1,VDR,LSS,ALAD,DAGLB,PER1,IFT140,SENP3,HMBS,MAP2K4,AP2S1,GPATCH4 |
| 5.276e-05 | -9.85 | GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP | 189 | 44 | 17758 | 2279 |
SEPHS2,ESCO1,CELSR1,DDX18,PPHLN1,HES6,SF3A3,SIRT2,GYG1,MLH1,OPA1,ABHD6,MBNL1,RSRC1,GIT2,NDUFS7,MPHOSPH10,PI4KB,NISCH,ANAPC10,KDELC1,CASP8AP2,TRIM14,FAM120B,DDX28,KDM5B,FAM172A,TSPYL4,NOL8,EIF2A,PHF6,GLS,TRAP1,CC2D1B,ZZEF1,CSRNP1,ALKBH1,ADAM9,SIL1,POLR1C,C12orf45,PDSS2,TSPAN5,XPO6 |
| 5.325e-05 | -9.84 | JmjC | pfam domains | PF02373 | 23 | 11 | 16629 | 2165 |
KDM6B,KDM3B,HR,KDM5B,KDM2A,KDM4B,KDM5A,JMJD1C,JMJD6,KDM5C,KDM4C |
| 5.376e-05 | -9.83 | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | 3665 | 541 | 17775 | 2278 |
ARHGAP26,ADAM19,GNB3,THOC5,ACTG1,CACNA1H,PCDH7,C1orf159,PDZD2,ZFHX3,NSRP1,SYN2,THAP4,RABGAP1L,ZNF148,KDM5C,SRRM2,FTSJ3,KIF15,RFX2,AKAP12,MCL1,DDX3X,AHNAK,BRCA2,SSU72,DIRAS1,SLC25A26,MEF2C,TRIO,PRAF2,NHS,BTBD9,RSF1,YARS2,ABCA7,RSPRY1,DHX37,KIAA1671,MCM5,ALKBH8,WDR60,ANP32B,CCDC88C,PABPC1,PPA1,HMGCR,FADS1,TIMM8B,STAG1,KCNQ3,RB1CC1,PRDM16,EPS15L1,ZNF512B,RYR2,USP10,MAP7D1,DYNC1H1,VPS13C,LRP1B,NME7,TRAP1,LEMD3,WDR33,MB21D2,COG5,GALE,RAB11FIP4,ZNF516,TRERF1,GRINA,ST3GAL6,RPGRIP1L,RPP30,ZBED2,ABCA12,SETD5,WAC,ATRIP,MSH4,ZC3H3,LYST,GARS,KMT2D,FAM111B,ARHGEF10,LGALS1,PCNXL2,KCNH3,TTC28,DSP,TAF2,FBXL5,IQCH,ASTN2,WDR7,PAM,ANKS1A,LAMA5,CEP170,YEATS2,BAG1,MAPT,TRIM36,COMMD10,INSIG2,XRRA1,WDR37,ATG2B,AKT1S1,KRI1,ACAP3,UNC13A,ARHGAP1,ZNF710,FBXL19,HNRNPM,SPTAN1,ARHGAP39,RSBN1,CCDC113,PPIP5K2,DDX49,SRCAP,NSD1,PXDN,NME1-NME2,ARID3B,HERC1,ERVMER34-1,SLCO5A1,SLC25A19,ANAPC4,CYP24A1,FAM227A,WDR13,POLR1A,PPARGC1B,GIT2,BIRC2,FRRS1,ARHGAP18,ANKRD11,METTL8,UBAP2L,SLC25A23,VPS13B,TMPO,FLNC,FMNL3,CHD9,SLC3A2,MIOS,BAZ2A,SKIV2L2,NOL6,LAMA2,BRCA1,KIF16B,BSN,TCF7L1,TOM1L2,TECPR2,CCDC146,SOCS4,RAD51B,SGSM2,MAGI1,USP15,SARS,LRRC28,CLK1,RLF,DNAH1,DOPEY1,RNF40,CEP290,PPIL2,ALDH18A1,CWF19L2,LRSAM1,TRAPPC9,CAMKK2,TLE3,WDR25,OBSCN,RNH1,MEX3B,ZNFX1,NR2F1,VAC14,NAP1L5,GRIK4,FAM135A,PALB2,SYNCRIP,DNAH17,PPP1R12B,DTD1,USP7,NDUFA5,CYLD,UPK3B,NDUFAF2,RPS29,RIPK1,LPCAT3,TNKS1BP1,RADIL,PPP1R9A,DDX60L,CAD,ZNF608,JAG1,NUP133,UBR1,ARMC5,FSIP2,FGGY,ANKRD24,ZFP37,ANO8,MYH15,CORO1A,TMEM200A,KDM3B,KAT8,WDR36,ARHGAP17,THSD4,TMEM123,SLC35F2,VIM,AKAP13,CA5B,ENC1,ZNF251,BTBD11,ATG7,INTS9,NFASC,EIF2B3,PARD3,UNC13D,DMGDH,MIF4GD,RFX1,FAM46B,RBM19,FOXP1,CSNK1A1,POGZ,IQGAP2,TTC1,PRICKLE2,CPNE7,CD44,LRRIQ1,MON1A,TOP3A,DHX34,PEAR1,RAP1GDS1,ARHGEF12,PALLD,ARMC3,POLR3A,C20orf196,GPC2,DSC2,CSRNP1,BCAS3,RBPJ,TAF12,ITGB4,NR2F2,XPO6,ZNF292,MYCBP2,POLB,ENAH,NBEAL1,AARS,UBR5,EXOC1,RNF111,CHD2,CSGALNACT2,SPAG6,ZNF646,SETD1B,OSBP2,CUX1,CAMSAP2,ZDHHC14,SON,DDX60,DOT1L,SH3GL1,GZF1,HSDL2,HSPBAP1,VPS13D,GREB1L,DNAH2,FAM118A,ZNF598,PTPN14,CELSR1,DROSHA,PRPF31,ANKRD17,CENPB,GTF2IRD1,CCDC47,TGFBR2,MTUS1,PRKCE,TECTA,NAV1,ZNF586,NOVA2,PRPS1,DDX28,SIK3,RREB1,RAP1GAP2,ARID1A,PLCB1,MTR,DAGLA,ASCC3,ALKBH3,HIF1A,UBAP1,ZZEF1,SRP68,SPEN,VCAN,D2HGDH,DPEP1,NCOR1,SMYD3,ZFHX2,PPDPF,BIRC6,URB2,HFM1,KLHL18,PTPRG,FOSL2,PDE3A,IGSF1,BLOC1S2,CHD7,DECR1,SLX4,ARMC6,DTNBP1,MRPS27,NBEA,TTC3,CMPK1,SERPINH1,KMT2A,NAA35,ZCCHC14,GON4L,SFXN4,WDPCP,SATB2,MED16,MARCH6,ERC1,STK10,DHX57,DNTTIP1,YIPF2,H2AFX,LARGE,SLC4A7,TRMT2A,IFT140,ALKBH1,MDN1,TBXA2R,PDCD11,NCOR2,SSH2,BRAF,KIF5C,IKBKAP,FAM8A1,GIGYF2,ZNF239,COMMD9,NISCH,PMPCA,EXOSC4,C6orf163,NAV3,FER1L5,SLC40A1,TTLL5,WDFY3,PACS1,GUF1,MMAA,HELZ,ORC5,SVIL,ATM,BRWD3,IPO4,STK4,EIF3C,UBN1,KIF5A,FANCD2,SLC29A1,DST,ZNF804A,RTN1,YLPM1,CNIH3,ANAPC10,MYH3,ZEB1,GPATCH1,SLC27A5,CCDC121,YARS,TIMM50,ZBTB17,TNK2,TXLNG,VWCE,KSR2,MTHFD1L,SOX4,KMT2C,SGK2,CHAF1A,TMEM132B,CCDC3,EIF4ENIF1,SUFU,TRMT5,MKL2,RLTPR,CSMD3,DMTF1,DCAF5,TNRC6A,FN1,SCART1,PAX2,CEP164,SIPA1L3,ATXN2,NRIP1,ATP6V0D1,CPSF3L,PDE4A,TRA2A,JMJD1C,ZFP14,PRDM1,AGAP1,EXOC6,MYBBP1A,FSCN1,KIAA0355,FAT1,INTS5,SLC16A1,PFDN2,TBCK,PDE9A,PDSS2,ASH1L,PCNT,CELSR3,MYO7A,SMARCA4,DHX35,SLC39A1,ZC3H13,VPS18,PPFIBP1,SNTG2,SLC38A2,VCL,HTRA2,MAML3,PHLDB2,FAM172A,COL5A2,EDEM2,UBR4,ARMC4,DUS3L,IKZF4,HNRNPR,ZNF557,WDR73,HEATR1,ARC,RNF130,DISP1,BRD9,SMG1,YDJC,DNAJC2,DYM,CAMK1,VPS45,SEMA3E,MRPS11,MAN1A1,PRKCH,GART,MICAL3,SLC6A16,KDM6B,CRIM1,TEAD1,SULT4A1,MARS,MEN1,PDE2A,EIF5B,ZNF407,NAALADL2,NAPEPLD,MFN2,ALG5,CUL2,SLC16A10,HRH1 |
| 5.405e-05 | -9.83 | histone methyltransferase activity | molecular function | GO:0042054 | 56 | 19 | 16491 | 2164 |
ASH1L,KMT2D,SETD1B,KMT2E,SETD2,EHMT1,SETD7,MEN1,KMT2C,DOT1L,NSD1,EHMT2,SUV39H2,PRMT5,FBL,KMT2A,PRMT3,SMYD3,CARM1 |
| 5.418e-05 | -9.82 | WD_REPEATS_REGION | prosite domains | PS50294 | 239 | 52 | 11866 | 1504 |
DMXL2,WDR75,GNB3,PAFAH1B1,WDR13,PLRG1,PIK3R4,WDR26,WDR37,NUP43,CORO6,NBEAL1,DENND3,NLE1,AMBRA1,PEX7,WDR27,NBEA,PAK1IP1,CORO1A,UTP4,SEH1L,LYST,PRPF19,WDR36,FBXW4,WDR61,WDFY3,TLE3,WDR18,UTP15,WDHD1,WDR25,MED16,GEMIN5,SEC31A,PWP1,WDR5B,ELP2,WDR35,HERC1,WDR7,TSSC1,IFT140,PRPF4,TBL1X,APAF1,WDR33,WDR66,BRWD3,DCAF5,CORO2B |
| 5.470e-05 | -9.81 | GSE17721_LPS_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_2H_BMDM_UP | 195 | 45 | 17758 | 2279 |
SLC12A7,POLB,SEC24D,MRPL10,RCAN1,HLTF,LCLAT1,PCDH7,SNTG2,WIZ,CLDND1,KDM5C,CD44,PABPC1,PTPRK,IFRD1,TRIM13,FAM127A,AP4B1,HSPA5,MARCKSL1,ZNFX1,DDX60,PEAK1,ERC1,ISG15,TMEM186,MAT2A,DNTTIP1,APBB3,SMARCC1,DAGLB,ARNTL,VPS37B,SVIL,SCARB1,MED20,PFDN2,PSAP,NAPA,ECHDC1,NMD3,KIF1B,ARHGAP10,DCAF5 |
| 5.695e-05 | -9.77 | regulation of organelle organization | biological process | GO:0033043 | 1022 | 175 | 16441 | 2138 |
MYCBP2,CUL7,ATRX,CSNK2A1,BCOR,SIRT2,UBR5,AMBRA1,SKI,TOM1L1,SMARCB1,ABL2,ANAPC1,NEK6,ARHGAP18,SREBF2,S100A10,PMAIP1,YLPM1,ATG3,ANAPC11,ANAPC10,MAD1L1,DPH6,HRG,FXN,TBC1D8,ZBTB17,LIMA1,GMFB,WDHD1,HDAC8,CAMSAP2,CAV1,BRCA1,ARPC3,STOML2,PAF1,RHOU,TOM1L2,INSIG1,FIS1,PPP3CC,TPM1,UQCC2,SYNPO,C2CD5,MEF2C,CHMP4C,WDR75,CDC42EP2,CELSR1,STXBP6,PID1,PDCD5,SPIRE1,RNF40,PRKCE,MYC,ATXN2,CTR9,PRMT5,LRSAM1,CAV2,TERF2,MYB,WDR61,PAXBP1,ATAT1,EVI5,PLCB1,TRIM37,ARIH2,UBE2E1,TBC1D2,RPL28,FSCN1,HIF1A,CDK9,CNOT6,PFDN2,NCOR1,SGSM3,CHMP2A,ID1,CYLD,FEZ2,PAFAH1B1,ACTR3,C16orf45,GPR143,STAM,HSPA1A,UBL5,PLXNB1,SBDS,PDE3A,KDM1A,MIEF1,TERF2IP,VPS18,SLX4,ACD,TBC1D22A,CORO1A,ITGAX,KMT2A,HTRA2,CTC1,PHLDB2,EVL,RAB7A,GRHL3,PREX1,ARHGEF10,SETD7,DKC1,TBC1D16,USP36,SNCA,SMAD3,MSX2,CAMK2D,CDC16,PEMT,NSMCE2,ATG7,IFT140,ANXA2,MID1,PKIB,MAPT,SSH2,BRAF,SUPT6H,CAMK1,MAP1S,ARFIP2,SEMA3E,OPA1,NOL3,RPS6KA5,PIP4K2A,MAD2L2,IQGAP2,ABL1,TADA3,SNW1,TRIAP1,RDX,AMOT,ACTR3B,DMRT1,SPTAN1,DDHD1,PPP1R9B,MSX1,CEP295,KDM5A,ASAP3,TEX14,PTK2,POLR3A,ANXA1,INF2,NSD1,KLHL22,STX18,SET,VPS37B,BCAS3,ATM,BMP4,UQCC1,ANAPC4 |
| 5.710e-05 | -9.77 | S-adenosylmethionine-dependent methyltransferase activity | molecular function | GO:0008757 | 131 | 34 | 16491 | 2164 |
ASH1L,KMT2E,METTL16,SUV39H2,TRMU,FBL,PRMT5,KMT2A,COQ3,PRMT3,FTSJ3,CARM1,METTL1,KMT2D,SETD1B,RNMT,EHMT1,SETD2,PCMT1,METTL2A,METTL15,KMT2C,MEN1,SETD7,MTR,DOT1L,NSD1,EHMT2,TRMT5,PEMT,CAMKMT,SETD6,METTL2B,SMYD3 |
| 5.803e-05 | -9.75 | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 184 | 43 | 17758 | 2279 |
KLHL24,CHST11,WDR74,B4GALT5,TMEM109,MAPK8IP3,NAT10,BHLHE40,RLF,DENND3,RSRC1,LPIN1,KDM2A,IKZF5,ASAP1,XRCC2,ANKRD11,ETF1,ZNF148,POLR1B,ATF4,C1QTNF1,GMFB,MARCKSL1,MAPK1IP1L,ARID1A,R3HDM2,SOX4,RHOT2,SLC50A1,POLR2A,MAT2A,RERE,RAD54B,LMBR1L,GADD45A,CHD3,HK2,ZNF160,TNFRSF10D,RABEP1,MUTYH,SGSM3 |
| 5.831e-05 | -9.75 | BENPORATH_OCT4_TARGETS | MSigDB lists | BENPORATH_OCT4_TARGETS | 278 | 59 | 17758 | 2279 |
TCF12,USP7,AUH,JUP,FOXO1,PRPF31,CNTNAP3,H2AFJ,ID2,ZFP36L1,RNF24,ZIC2,SSBP2,TRIM22,PHGDH,UBR5,ARID1B,PTPN2,ACD,NEBL,ZDHHC6,VPS52,JOSD1,DDX31,ANO8,PRPS1,HN1,LAMA4,WDR36,KIAA1143,FGF2,WDFY3,TLE3,SMARCAD1,TRA2A,RDH10,KIF15,CPT1A,LSG1,FGFR1,RAD54B,MLLT10,DKK1,POLR3G,SKIL,INF2,TCF7L1,SPAG9,GATA6,SET,LARGE,ALKBH1,EIF2S1,TAF12,NR2F2,TXN2,PARD3,TNRC6A,KAT6A |
| 5.844e-05 | -9.75 | seminoma | COSMIC cancer mutations | seminoma | 726 | 129 | 17775 | 2278 |
NF1,PTPRA,TNFRSF21,TRPM6,CSNK2A1,STK33,PRKCA,NLE1,MAP2K3,RTN1,ABL2,ANAPC1,SRSF2,SREBF2,NEK6,ATG3,SRRM2,CDK6,LONP1,PRKACB,SRPK2,LAMA4,FLNC,TNK2,NRAS,CDK4,ANK2,AP4B1,NOL6,KSR2,LAMA2,SGK2,SON,DYRK1B,TRRAP,HLCS,SOCS4,SGSM2,CSMD3,RIOK1,TSEN2,WDR66,TAF1,CLK1,TRIO,PIK3R4,TGFBR2,DNAH1,PRKCE,SIPA1L3,ASAP1,SCAF1,PDE10A,MAP3K12,PABPC1,SIK3,CAMKK2,OBSCN,C19orf70,MTR,ATP9B,DYNC1H1,ZZEF1,SNAP23,RIOK3,GPN1,TBCK,MAP2K4,CHMP2A,UPK3B,BIRC6,URB2,PDK4,DDR2,RIPK1,SMARCA4,RIOK2,FLAD1,PRKD3,ANKRD13A,BRE,CCDC50,RPS6KL1,IKBKB,ADCK4,MET,CDK12,ZCCHC14,BRD4,PDK1,SFSWAP,TBC1D16,STK10,FGFR1,TJAP1,CAMK2D,HIPK2,RPS6KB1,MDN1,SMG1,BCKDK,SSH2,TNIK,BRAF,SULT1C2,SUPT6H,MAP3K13,CAMK1,ATG2B,CSNK1A1,FAM49A,FOXO3,PRKCH,ABL1,PVRL3,PRICKLE2,CLK2,RPS6KB2,SPTAN1,TTLL5,TEX14,OXSR1,TRIB3,SRD5A3,ATM,RPS6KC1,ZAK,KIF1B,STK4 |
| 5.846e-05 | -9.75 | DEAD | pfam domains | PF00270 | 66 | 21 | 16629 | 2165 |
SKIV2L,DDX28,DDX41,DDX24,SKIV2L2,DDX18,HFM1,EIF4A2,DDX19A,DDX60,DDX60L,DDX49,DHX57,DDX3X,DDX56,ASCC3,DDX50,DHX37,DHX33,DDX31,DDX10 |
| 5.928e-05 | -9.73 | POLR1C (polymerase (RNA) I polypeptide C) | protein interactions | 9533 | 98 | 29 | 16036 | 2270 |
BCCIP,WDR36,PMS1,FAM208B,FN1,DDX24,DDX18,POLR1A,ABCF2,VIM,DKC1,UBC,PUM3,POLR3A,POLR3G,TSR1,POLR3D,DHX37,TP53BP1,CRCP,ATRIP,CORO1A,CLU,POLR1B,POLR3B,NFKBIB,USP11,NMD3,POLR1E |
| 5.939e-05 | -9.73 | purine ribonucleotide catabolic process | biological process | GO:0009154 | 27 | 12 | 16441 | 2138 |
HPRT1,AMPD3,PDE4A,ITPA,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,NT5E,PDE8B |
| 5.960e-05 | -9.73 | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | 471 | 90 | 17758 | 2279 |
CDCP1,ID1,TRIM16,ADAMTS6,BCOR,SSBP2,CCNL2,BIRC2,MAP2K3,PCDH7,ABL2,DST,ANKRD13A,PMAIP1,SLC38A2,SOCS6,KIAA0922,MET,VCL,LYST,TBC1D8,SSFA2,ATP6V0A1,AKAP12,LRRC8A,HSH2D,AKAP13,MEF2D,MAK16,S100A16,MAT2A,SKIL,SMAD3,TAF2,DYRK1B,ARHGAP21,CAMK2D,SH3RF1,CCNT1,ZNF557,ARNTL,ARL13B,DLX2,USP11,MAGI1,NRP1,LRCH1,SLC12A7,EFNB2,WDR75,INSIG2,ARL15,SLK,TGFB2,RPS6KA5,PHLDA2,NEDD4,DDIT4,PRKCH,DOPEY1,UBE3A,CEP290,IFIT5,MYC,SDCBP2,SYNJ2,NOC3L,MAP3K14,FBXO31,NRIP1,TOMM34,PPAT,CRIM1,ARID5B,TPM4,RNH1,IL6R,PALLD,KLF6,ANGPTL4,FOXC1,TBC1D2,OXSR1,GPC2,GADD45A,HIF1A,WDR35,TMEM117,PDLIM5,FNBP1L |
| 5.997e-05 | -9.72 | MEN1 (multiple endocrine neoplasia I) | protein interactions | 4221 | 57 | 20 | 16036 | 2270 |
KMT2D,DROSHA,TAF1,FOXN3,TCF3,DBF4,FANCD2,MYH9,VIM,MEF2D,MEN1,TCF7L2,POLR2A,SMAD3,SNW1,MYC,SENP3,KMT2A,HCFC2,MYB |
| 6.022e-05 | -9.72 | TGCACTT,MIR-519C,MIR-519B,MIR-519A | MSigDB lists | TGCACTT,MIR-519C,MIR-519B,MIR-519A | 433 | 84 | 17758 | 2279 |
RBM33,BIRC6,NF1,NPAS2,PAFAH1B1,KIF5A,TNFRSF21,FAM13A,TNKS1BP1,LCLAT1,UBR5,GBF1,SKI,RTN1,SRSF2,KDM2A,SYN2,DNAJB6,SOCS6,MMP14,NBEA,CMPK1,CDK12,SOBP,CHD9,PREX1,NFIA,R3HDM1,AKAP13,SOX4,RAB10,DCBLD2,YTHDF2,FBXL5,DDX3X,IKZF4,KPNA3,ZNF236,ABHD3,HOXA3,SLC4A7,TNRC6A,USP15,HMGA2,SSH2,SMAD7,TGFBR2,MBNL1,IGF2BP3,PTPN2,SACS,UBE3A,PI4KB,ARHGAP1,IGF2BP1,LARP4B,MAP3K12,CNOT4,PKNOX1,MYB,GATAD2B,FGF9,SLC40A1,WDFY3,TEAD1,PPP1R21,RAPGEF4,ZNF512B,ZNFX1,FAM126B,PLCB1,SYT1,CACNB1,L3MBTL3,HIF1A,TBX3,PTPN4,PURB,ARHGAP12,CNOT6,TBL1X,FNBP1L,SH3PXD2A,C18orf25 |
| 6.027e-05 | -9.72 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | 190 | 44 | 17758 | 2279 |
AOC3,MINK1,SESTD1,MEX3A,SMAD7,GTF2IRD1,PPP1R1C,BHLHE40,GIT2,MTUS1,SKI,ABL1,CD96,PPIL2,NDRG4,GREB1,TTC3,ALDH18A1,LDLRAD3,AMOT,SPTAN1,NT5E,SLC40A1,PHLDB2,FMNL3,NR6A1,CUX1,ATF7IP2,ATXN1,PACS1,PDE2A,EXOG,TBC1D16,TMEM186,CTIF,GNG2,SKIL,SLC39A14,SYCP2L,IKZF4,CHD3,SYNGR2,GREB1L,NRP1 |
| 6.027e-05 | -9.72 | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN | 190 | 44 | 17758 | 2279 |
SRM,TCF12,DDX18,LARS2,PRPF31,DBF4,ALG8,REEP5,BZW2,RPP30,FKBP1A,DNAJB6,ATIC,CTR9,RDX,BCAP29,PRMT5,AVEN,COQ3,TRIP13,TOP1,MYB,TIMM8B,PSAT1,POLA1,ABCF2,CPOX,ODC1,MAT2A,CHAF1A,TIMM44,WARS,VDR,TAF2,ATAD5,NME7,TRMT5,HNRNPR,POLR3E,PRPF4,NOLC1,ECHDC1,AP2S1,IPO4 |
| 6.255e-05 | -9.68 | negative regulation of cellular macromolecule biosynthetic process | biological process | GO:2000113 | 1310 | 217 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,SKI,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,KDM5C,HCFC2,PTPRK,DEAF1,HMBOX1,RBCK1,AEBP2,ATF4,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,BRCA2,SUPT4H1,EIF4ENIF1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,TNRC6A,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,PID1,BARX2,ZIC2,RSF1,CDC73,ABCA7,IGF2BP3,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,IGF2BP1,NRIP1,TERF2,MYB,ZNF675,GATAD2B,PAXBP1,RREB1,PRDM16,ARID5B,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,EPRS,MYBBP1A,SYNCRIP,EHMT2,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,AGO3,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,CYLD,MAP2K5,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,PAIP2,ZBTB21,ACD,PPID,DNAJB6,RNF2,CTC1,MOSPD1,SAP30,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,ENC1,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,EIF2B3,SETD6,YEATS2,HMGA2,DNAJC2,NOSTRIN,NCOR2,TCF3,AGO2,H2AFJ,NFX1,ID2,IGF2BP2,ATF7IP,GAS6,BHLHE40,RPS6KA5,FOXP1,GIGYF2,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,CELF1,YBX3,SAMD4A,DMRT1,SOX6,FGF9,MSX1,KDM5B,PSPC1,FOXN3,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,ZRANB3,RERE,DKK1,MKX,TRIB3,NSD1,IREB2,TBX3,SET,EIF2S1,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 6.327e-05 | -9.67 | GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN | MSigDB lists | GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN | 303 | 63 | 17758 | 2279 |
UNC13D,MINK1,CUL7,RBM33,URB2,TCF3,MAPK8IP3,SMARCA4,SMG7,VARS,TMEM132A,LTB4R,SAFB2,SNAPC4,ANKRD54,ABCA7,FKBP1A,ZNF358,ARMC6,PHF5A,DHX33,SCAF1,SETD5,TRMU,UBAP2L,TNPO3,COPS7B,TTC17,TSPAN14,FBXL19,SRRM2,ZNF646,KAT8,ARHGAP17,TNK2,SFSWAP,NPM3,EYA3,NOL8,RAP1GAP2,XPO5,ATAT1,RANGAP1,MEF2D,LENG8,NUP214,SYMPK,DOT1L,SLC23A2,SRCAP,TRRAP,GPC2,DAGLB,EHMT2,CC2D1B,PQBP1,MDN1,PUS1,ZNF598,RNF214,C7orf26,SGSM3,TMCC1 |
| 6.394e-05 | -9.66 | HNRNPC (heterogeneous nuclear ribonucleoprotein C (C1/C2)) | protein interactions | 3183 | 153 | 40 | 16036 | 2270 |
SART1,CUL7,FN1,UTP14A,KHDRBS1,CSNK2A1,SMARCA4,CSNK1A1,MYC,BANF1,AP1M1,VAPB,RNF2,CELF1,SRRM2,HNRNPM,TOP1,SRPK2,SF3A1,SNU13,PRAME,PTBP2,TRA2A,ZC3H18,WDR18,GNL1,BRCA1,PHF6,UBC,RANBP2,BRCA2,MYBBP1A,PALB2,KPNA3,SMARCC1,HNRNPR,COPS5,CUL2,H2AFX,CCDC85B |
| 6.408e-05 | -9.66 | histone methylation | biological process | GO:0016571 | 81 | 24 | 16441 | 2138 |
KMT2D,ASH1L,SETD1B,WDR61,BAZ2A,KMT2E,SETD2,EHMT1,SETD7,KMT2C,MEN1,CHD5,DOT1L,NSD1,SUV39H2,EHMT2,CTR9,FBL,PRMT5,KMT2A,SETD6,PRMT3,SMYD3,CARM1 |
| 6.413e-05 | -9.65 | LI_DCP2_BOUND_MRNA | MSigDB lists | LI_DCP2_BOUND_MRNA | 87 | 25 | 17758 | 2279 |
CHMP2A,DEAF1,GLTSCR2,WDR74,IDH3G,HSD17B10,JMJD6,APRT,HMOX2,PHGDH,SAP30BP,ETFB,NDUFS7,MRPS11,CHAF1A,NOP56,BAZ1A,FAM50A,TRIB3,DCXR,SPEN,TTC3,EXOSC4,SRRM2,AP2S1 |
| 6.420e-05 | -9.65 | replication fork | cellular component | GO:0005657 | 63 | 20 | 17570 | 2233 |
RFC4,MCM10,RFC3,PRIM2,POLA1,SMARCAD1,PLRG1,ZRANB3,RPA1,BCAS2,POLE2,RAD18,TP53BP1,XRCC2,RAD51B,H2AFX,PURB,POLE3,PRPF19,TOP1 |
| 6.477e-05 | -9.64 | GCM_UBE2N | MSigDB lists | GCM_UBE2N | 151 | 37 | 17758 | 2279 |
ZNF292,EPM2AIP1,RBFOX2,TMEM183A,IKBKAP,FOXO3,POGZ,COMMD9,DCTN4,VPS52,RAN,CELF1,ZMYM2,PKNOX1,RANBP6,CHD9,PTBP2,TSPYL4,BAZ2A,IDH3G,RSBN1,ARID1A,MARCH6,UBE2K,APBB3,EIF4ENIF1,SUFU,KIDINS220,ADNP,HNRNPR,ASTN2,HNRNPH3,LUC7L3,LEMD3,CLEC16A,CNOT6,CEP170 |
| 6.499e-05 | -9.64 | - | gene3d domains | 3.40.50.300 | 733 | 139 | 9988 | 1398 |
ATRX,DDX19A,HLTF,RAC3,SRPRB,RAP1A,CMSS1,YLPM1,DHX33,XRCC2,CHD2,RAN,TRIP13,LONP1,CHD9,NRAS,ABCC4,SKIV2L2,KATNAL1,GNL3,ABCC2,MTHFD1L,MCM2,DDX60,LSG1,GNAI1,PEX1,RHOU,DDX3X,ZGRF1,CHD3,EEFSEC,ARL4A,RAD51B,ABCC3,DNAH2,DIRAS1,EP400,AK2,MCM6,RHOBTB1,AK6,CHD5,DNAH1,ABCA7,DDX56,NAV1,DHX37,ABCA5,MCM5,CACNB2,N4BP2,MTHFD1,DDX28,EIF4A2,RAP1B,BCS1L,ZNFX1,AGAP1,ABCF1,DNAH14,DYNC1H1,ASCC3,ATAD5,NSF,RRAGA,GPN1,DDX10,N4BP2L2,HS2ST1,DNM3,ABCA3,DDX18,ATP6V1A,HFM1,OLA1,SMARCA4,MCM9,CBWD5,DDX60L,DHX35,CHD7,NUBPL,ABCA12,NVL,MSH4,CMPK1,SKIV2L,RFC4,RFC3,MPP6,DDX41,RAB7A,MTIF2,DLG4,GNL1,ARL5B,RAB10,DHX57,RAD54B,ARL13B,CBWD1,MDN1,SEPT5,RAB30,VWA8,SULT1C2,ARL15,C10orf2,OPA1,GFM2,MFHAS1,CBWD6,DDX31,DYNC2H1,NAV3,PFKFB4,DDX24,ZFYVE1,SMARCAD1,ABCF2,SULT4A1,DHX34,BMS1,EIF5B,RHOT2,GUF1,DDX49,MMAA,MFN2,ZRANB3,CACNB1,SRCAP,DDX50,HELZ,MPP7,ORC5,MSH3,APAF1 |
| 6.500e-05 | -9.64 | MLLT1 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1) | protein interactions | 4298 | 29 | 13 | 16036 | 2270 |
PAF1,ELL,BRD4,CCNT1,CDK9,CSNK2A1,ARID1A,BCOR,KMT2A,RFXAP,POLR2A,MLLT10,DOT1L |
| 6.522e-05 | -9.64 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 177 | 42 | 16441 | 2138 |
SART1,POLB,CUL4A,TMEM109,CDIP1,MLH1,CHAC1,ZNF346,NOL3,PRKCA,DDIT4,ABL1,SNW1,PMAIP1,FNIP2,FHIT,PERP,HTRA2,ATF4,PDK1,MCL1,SHISA5,BRCA1,UBE2K,DDX3X,TRIB3,ZNF622,BRCA2,MYBBP1A,HIPK2,ARL6IP5,CUL2,TNFRSF1A,AEN,ATM,PPP3CC,CLU,APAF1,BRSK2,ZMAT3,DDIT3,MAPT |
| 6.637e-05 | -9.62 | MORF_RPA2 | MSigDB lists | MORF_RPA2 | 185 | 43 | 17758 | 2279 |
MVK,DDX18,PRPF31,PRKCSH,FAM189B,KHDRBS1,CSNK2A1,VARS,XPO7,PARN,PITPNM1,CAD,ABL1,EIF2S2,SREBF2,CNOT4,KDM3B,GTF2H3,LSM12,SFSWAP,PARP2,WDR18,LDHA,PCMT1,PSMA1,ADSL,MEN1,MCM2,SERP1,DDX49,POLR2A,ARIH2,MFN2,PWP1,SMARCC1,E2F4,COQ9,TIMM17A,NFRKB,USP11,COPS6,BMI1,XPO6 |
| 6.754e-05 | -9.60 | hepatocellular_carcinoma | COSMIC cancer mutations | hepatocellular_carcinoma | 15590 | 2053 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,ABHD6,LPAR3,CIAPIN1,SKI,ZFHX3,ATP5G2,THAP4,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,ST3GAL6,LCLAT1,ZMAT2,MCM9,CD96,SPG21,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,TSN,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,MBD2,NDRG4,VAPB,WNT16,LRSAM1,SNX29,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,CSGALNACT2,ACADS,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,SFR1,ABL1,NEBL,SDCBP2,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,PDE9A,DMXL2,TCF12,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,ALAD,KPNA3,DUS3L,ARNTL,FKBP5,NFRKB,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,FIP1L1,MEF2C,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,KIAA1671,SLC38A5,NOC3L,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,FAM50A,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ALDH1L2,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,OLA1,C1QTNF7,SPATS2L,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,ETFB,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,UBAP2,MYBBP1A,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,SLC9B2,GBF1,ZSCAN5A,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,UTS2,AMOT,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,CYP24A1,CUL7,RBM33,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,OSBPL9,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,FERMT2,RANGAP1,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,NIT1,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,RABGAP1L,FAAH2,RASSF3,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,DNM3,ZNF516,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,PES1,GNG2,TAF2,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,JMJD6,BHLHE40,MBNL1,POM121,KRI1,GATC,PVRL3,SOX6,DIS3L2,ULBP1,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TRIB3,TOE1,RARS,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,C16orf52,MEX3A,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,PPIL2,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,MSH3,EIF2S1,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,GNG7,EYA3,NOL8,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,TXN2,ZNF598,PTPN14,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,SCAF11,ADARB1,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,SERF2,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,PEX13,RTTN,PPDPF,RIBC2,URB2,ZBTB37,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,ZNF827,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,PFKFB4,FAM120B,KCNMA1,FZD3,TBRG4,OASL,NOP58,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,WNT2B,EDC3,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,NBR2,SH2D3A,SULT1C2,DBF4,CLSTN2,CCDC7,CTNNBL1,DSG2,SHMT2,TTC17,DMRT1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,ZAK,ARHGAP27 |
| 6.754e-05 | -9.60 | liver-carcinoma-hepatocellular_carcinoma | COSMIC cancer mutations | liver-carcinoma-hepatocellular_carcinoma | 15590 | 2053 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,ABHD6,LPAR3,CIAPIN1,SKI,ZFHX3,ATP5G2,THAP4,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,ST3GAL6,LCLAT1,ZMAT2,MCM9,CD96,SPG21,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,ZNF710,ACTR3B,C15orf41,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,TSN,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,MBD2,NDRG4,VAPB,WNT16,LRSAM1,SNX29,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,CSGALNACT2,ACADS,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,SFR1,ABL1,NEBL,SDCBP2,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,PDE9A,DMXL2,TCF12,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,ALAD,KPNA3,DUS3L,ARNTL,FKBP5,NFRKB,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,FIP1L1,MEF2C,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,KIAA1671,SLC38A5,NOC3L,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,SLC25A19,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,BCAS4,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,FAM50A,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ALDH1L2,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,OLA1,C1QTNF7,SPATS2L,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,ETFB,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,UBAP2,MYBBP1A,HK2,ZFP90,TMEM182,ZBTB24,MYO7A,SLC9B2,GBF1,ZSCAN5A,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,UTS2,AMOT,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,CYP24A1,CUL7,RBM33,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,OSBPL9,RIPK1,SSBP2,TIGD1,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,PLAC8L1,FERMT2,RANGAP1,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,SYT17,UROD,POP5,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,GPATCH1,ZEB1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,TIMM10,ELL,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,NIT1,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,RABGAP1L,FAAH2,RASSF3,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,DNM3,ZNF516,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,PES1,GNG2,TAF2,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,SF3A3,ID2,JMJD6,BHLHE40,MBNL1,POM121,KRI1,GATC,PVRL3,SOX6,DIS3L2,ULBP1,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TRIB3,TOE1,RARS,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,C16orf52,MEX3A,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,PPIL2,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,DDX31,SELT,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,MSH3,EIF2S1,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,GNG7,EYA3,NOL8,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,TXN2,ZNF598,PTPN14,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,SCAF11,ADARB1,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,SERF2,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,PEX13,RTTN,PPDPF,RIBC2,URB2,ZBTB37,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PHC2,ZNF827,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,PFKFB4,FAM120B,KCNMA1,FZD3,TBRG4,OASL,NOP58,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,WNT2B,EDC3,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ATAD5,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,UBTD2,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,NBR2,SH2D3A,SULT1C2,DBF4,CLSTN2,CCDC7,CTNNBL1,DSG2,SHMT2,TTC17,DMRT1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,ZAK,ARHGAP27 |
| 6.808e-05 | -9.59 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | 537 | 100 | 17758 | 2279 |
ADAM19,SPRED2,SYT17,MYH9,TUBB6,TMEM132A,PRKCA,HMOX2,ST3GAL6,CIAPIN1,SRPRB,RTN1,ABL2,PRKD3,ECM1,SLX4,NEK6,PMAIP1,CNIH3,TBC1D22A,GLYR1,AHCYL1,MET,VCL,HN1,ACSL5,SLC3A2,CMIP,EYA3,TFPI,MARCKSL1,SOX4,EDEM2,UBR4,ST3GAL5,MGST1,TMEM206,BATF3,SLC7A1,GLS,G6PD,NSMCE1,HIPK2,H2AFX,SLC25A11,ABCC3,FKBP5,RUNX1,NRP1,NMD3,PKIB,LPP,TNIK,AUH,FN1,MAP3K13,TCF3,UBXN1,SMAD7,ID2,RCAN1,TIMM10,CD226,PHLDA2,BZW2,CMTM3,MAD2L2,SLC39A11,DCTPP1,SUB1,KIAA1671,PTRF,SLC7A11,ASAP1,NISCH,TRIAP1,PTGS1,GLTP,TOMM34,FMNL2,RABEPK,PEA15,CRIM1,FOXN3,HOMER2,PHACTR2,CYB5B,VAC14,YIF1A,MTHFD2,NME7,FSCN1,TRAP1,COQ9,SDCCAG8,MB21D2,ZAK,C12orf45,ARHGAP10,STK4 |
| 6.896e-05 | -9.58 | LIAO_HAVE_SOX4_BINDING_SITES | MSigDB lists | LIAO_HAVE_SOX4_BINDING_SITES | 40 | 15 | 17758 | 2279 |
PFKFB4,UBAP2,VCAN,HSPBAP1,SLC2A1,UBAP2L,PAM,HIC2,SEMA3C,GYG1,ALDH18A1,NRP1,PTPN14,DKK1,NAV3 |
| 6.928e-05 | -9.58 | chromatin binding | molecular function | GO:0003682 | 463 | 90 | 16491 | 2164 |
ASH1L,ATRX,SMARCA4,SIRT2,FOSL2,PELP1,RING1,KDM1A,SKI,SMARCB1,CHD7,CAMTA2,WAC,RELB,ZEB1,RNF2,SSBP1,RAN,MEIS3,KMT2A,BRD4,SIRT6,PPARG,EYA3,GRHL3,NFIA,CUX1,ATXN1,WDHD1,POU2F1,SATB2,SETD7,CHAF1A,TAF2,PAF1,SMAD3,UBTF,SKIL,DNTTIP1,TCF7L1,SMARCC1,GATA6,CCNT1,ADNP,PER1,DLX2,BEND6,MEF2C,HMGA2,DNAJC2,FOXO1,ANKRD17,TCF3,SIRT7,CENPB,BARX2,ZIC2,CHD5,FOXO3,TOX4,POLR3D,MCM5,MBD2,SHMT2,NOC3L,DMRT1,TOP1,GATAD2B,KDM6B,APEX1,STAG1,KDM5A,POLA1,SMARCD3,APTX,ARID1A,SUPT5H,MEN1,TRIM37,POLR3A,TCF7L2,RPA1,RERE,NSD1,ATXN7,CDK9,BCAS3,RBPJ,MBD6,KAT6A |
| 6.933e-05 | -9.58 | JMJC | prosite domains | PS51184 | 32 | 13 | 11866 | 1504 |
KDM6B,KDM3B,HR,KDM5B,KDM2A,KDM4B,KDM5A,HSPBAP1,JMJD1C,MINA,JMJD6,KDM5C,KDM4C |
| 6.955e-05 | -9.57 | UTP15 (UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)) | protein interactions | 84135 | 22 | 11 | 16036 | 2270 |
WDR36,MPHOSPH10,SIRT7,ANAPC10,RNF2,HEATR1,RBM19,FBL,NOP58,UBR5,UTP4 |
| 7.014e-05 | -9.57 | SREBP signalling | WikiPathways | WP1982 | 64 | 20 | 4455 | 564 |
SEC24A,INSIG2,SEC24D,PPARG,PPARGC1B,LPIN1,SEC31A,LSS,IDI1,SREBF2,INSIG1,SEC24C,MED15,FDPS,SQLE,SCARB1,GPAM,FDFT1,HMGCR,MBTPS2 |
| 7.025e-05 | -9.56 | PENG_LEUCINE_DEPRIVATION_UP | MSigDB lists | PENG_LEUCINE_DEPRIVATION_UP | 135 | 34 | 17758 | 2279 |
CARS,SARS,CAMK1,ST6GAL1,UBXN1,MLH1,PHGDH,GBF1,AARS,DECR1,ASNS,BUD31,CLCN6,SHMT2,KIAA0922,PCK2,ATF4,GARS,SLC3A2,TRA2A,CUX1,MARS,RERE,PYCR1,WARS,SLC7A1,APBB3,MTHFD2,SPAG9,CTAGE5,SURF1,PSAP,BMI1,SLC43A1 |
| 7.070e-05 | -9.56 | Pyrimidine metabolism | KEGG pathways | hsa00240 | 104 | 28 | 6908 | 881 |
PRIM2,ITPA,POLR1A,POLA1,UPP1,NT5C3A,POLR3A,POLR2A,POLR3G,CAD,DCTPP1,POLR3D,NME1-NME2,POLE2,ENTPD5,NME7,POLR3E,UMPS,NT5C,POLR1B,POLE3,POLR3B,CMPK1,POLR1C,ZNRD1,NT5M,POLR1E,NT5E |
| 7.070e-05 | -9.56 | Pyrimidine metabolism | KEGG pathways | ko00240 | 104 | 28 | 6908 | 881 |
PRIM2,ITPA,POLA1,UPP1,POLR1A,NT5C3A,POLR2A,POLR3A,POLR3G,DCTPP1,CAD,POLR3D,NME1-NME2,POLE2,ENTPD5,NME7,POLR3E,UMPS,NT5C,POLR1B,CMPK1,POLE3,POLR3B,POLR1C,NT5M,ZNRD1,POLR1E,NT5E |
| 7.083e-05 | -9.56 | diffuse_adenocarcinoma | COSMIC cancer mutations | diffuse_adenocarcinoma | 4562 | 660 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,ASCC1,THOC5,DCP1B,AARS2,NAT10,CACNA1H,SBF2,CSPP1,HLTF,CCNL2,NUP160,SYNJ1,LPAR3,AMBRA1,TOM1L1,PCDH7,C1orf159,PDZD2,ZFHX3,RABGAP1L,PDS5B,LYRM5,SRRM2,ZNRD1,FTSJ3,CDK6,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,PTPRM,AP4B1,KIF15,WDHD1,SHISA5,SLC9A5,ZNF266,RIOK1,VASH2,ZNF532,SLC25A26,HERC2,KHDRBS1,TRIO,NHS,KCNJ14,YARS2,ABCA7,SLC39A11,RSPRY1,SH2B3,RBM20,DDX56,UBE3A,CNST,DHX37,APLF,MCM5,WDR60,CCDC88C,CALN1,COQ3,AGL,PABPC1,PPA1,MYB,NOM1,FADS1,GATAD2B,GTF2H3,IFRD1,COL17A1,STAG1,KCNQ3,RB1CC1,IDH3G,RYR2,ST6GALNAC3,MBNL2,SRA1,ZNF783,IRS1,DYNC1H1,VPS13C,LRP1B,TASP1,KPNA1,GTF2A1,CLASRP,CNOT6,WDR33,PDLIM5,MB21D2,SRP14,COG5,SPRED2,SDSL,RAB11FIP4,ABCA3,DNM3,ZNF516,TRERF1,PAFAH1B1,BTBD2,MAB21L3,DDR2,CD99L2,MYH9,GRINA,SAFB2,ABCA12,ACD,SETD5,FMNL1,WAC,MGLL,ZC3H3,DENND1A,KMT2D,ARHGEF10,ADAM32,PCNXL2,TTC28,DSP,FKBP3,MAT2A,FGFR1,ZFAND3,PES1,ELP2,ASTN2,POLR3E,CAMKMT,WDR7,HOXA3,BRCC3,ZBTB11,LAMA5,METTL2B,YEATS2,LRCH1,XPC,ATG2B,PSMF1,KRI1,ACAP3,UNC13A,ACOT11,ANXA5,LTN1,ACTR3B,C15orf41,SOX6,HNRNPM,LYPLA2,SPTAN1,DIS3L2,VPS37A,ARHGAP39,ZC3H18,NXN,MRPS10,PPIP5K2,ETFDH,SRCAP,NSD1,BAZ2B,PXDN,PLPPR2,PTPN4,AEN,PSAP,SORCS2,MTMR1,DOCK6,KDM4C,PPARGC1B,TFIP11,RNF43,TTI1,TMEM132A,SEC16A,MAP2K3,ARHGAP18,ANKRD11,HKR1,TRIML2,UBAP2L,ETV1,CDC37,VPS13B,FLNC,BAZ2A,SKIV2L2,KATNAL1,ANK2,SUMO3,FLVCR1,ZNF91,CRYBG3,KIF16B,BSN,MSRA,INSIG1,TP53BP1,CHD3,TECPR2,SGSM2,MAGI1,USP15,CTU2,OXNAD1,ITFG1,ITPRIP,MAPK8IP3,DNAH1,RNF40,ZNF358,ABCA5,CEP290,PDE10A,VAPB,TIMELESS,SYNJ2,GMDS,ALDH18A1,LAMC1,KTN1-AS1,CRADD,IFT43,SETD2,WDR25,OBSCN,ZNFX1,TRAPPC6B,NR2F1,VAC14,PGD,GRIK4,FAM135A,DNAH17,HMBS,GGT7,SH3PXD2A,USP7,SART1,ID1,PAPD4,ARID2,RPS29,NTSR1,LAGE3,SSBP2,DENND3,RADIL,TNKS1BP1,SEMA6A,PELP1,CAD,UBR1,DNAJB6,FSIP2,ANKRD24,ZFP37,MYH15,ANO8,CORO1A,AKNAD1,AHCYL1,PRMT3,CTC1,SOBP,TLCD1,KAT8,WDR36,SSFA2,THSD4,CPOX,VIM,AKAP13,NHSL1,NUP214,ARL5B,BTBD11,SMAD3,SLC30A3,KLF4,CLEC16A,ITGA2,TSSC1,NFASC,PPIL3,PARD3,ZNF507,DMGDH,ESCO1,AUH,MAP3K13,C14orf159,FOXP1,CSNK1A1,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,CWC27,PRICKLE2,SELT,CPNE7,C12orf4,HSD17B12,ADAMTSL3,LRRIQ1,PLAC8L1,TEX14,PEAR1,FERMT2,ARHGEF12,GPNMB,POLR3A,ZRANB3,TPD52L2,NOL10,CSRNP1,BCAS3,MSH3,EIF2S1,FNTB,RPS6KC1,GCSH,ZNF292,LRP5L,UBR5,LPIN1,GIPR,EXOC1,SUCLG2,RNF111,ME1,SPAG6,TBC1D8,DPF3,SEMA3F,ZDHHC14,SON,DENND4A,MAK16,SPOP,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,NSMCE1,GREB1L,DNAH2,TNFRSF10D,NMD3,EFNB2,DROSHA,CELSR1,LARS2,TATDN3,OPHN1,CCDC47,TGFBR2,CD226,MTUS1,TECTA,NAV1,ENTPD5,SLC7A11,NOVA2,ASAP1,SCAF1,COPS3,VWDE,PIGG,GTF3C3,LPCAT1,PRPS1,SCAF11,PRIM2,SYNGAP1,PCCA,RAP1B,PTPN12,TTYH2,ARID1A,TPRA1,EHBP1,MTR,PHF6,LYRM7,ATP9B,DAGLA,KIDINS220,ALKBH3,NSF,VCAN,SPEN,ZZEF1,ZCCHC6,SQLE,CNDP2,MACROD1,DHCR7,SMYD3,RTTN,PTCD2,TBKBP1,AMOTL1,TRPM2,BIRC6,URB2,HFM1,C1QTNF7,TMEM104,SPATS2L,PTPRG,FLNB,PDE3A,PAIP2,TERF2IP,ZNF827,ASNS,TMEM184A,SLX4,PPID,NBEA,SERPINH1,KMT2A,PLEKHA4,CDK12,NAA35,PREX1,KIAA1586,SATB2,MARCH6,MED16,SETD7,DHX57,BAZ1A,HTR7,ACP1,IFT140,TRAF3,KLHDC4,MDN1,MID1,NCOR2,BRAF,TTC27,TCF3,NFX1,RTN4,MLH1,MON2,OPA1,GIGYF2,FOXO3,MAD2L2,PTRF,NISCH,COPS7B,NLGN3,DYNC2H1,LARP4B,C6orf163,SLC40A1,TTLL5,WDFY3,FZD3,WDR18,ADSL,PACS1,OASL,NOP58,SLC23A2,KLHL22,ZDHHC11,HELZ,ORC5,STX18,RNF138,SVIL,ATM,APAF1,BRWD3,ADK,IPO4,IMMP2L,PIGM,MVK,UBN1,NF1,ATRX,KIF5A,FANCD2,PPIL1,SIRT2,BCOR,STK33,DST,ZNF804A,THADA,YLPM1,ZNHIT6,ATG3,MYH3,GPATCH1,ZEB1,IPP,PCOLCE2,SLC27A5,NDUFA6,TRIM14,TRIP13,LONP1,LAMA4,GPM6A,VWCE,TFPI,KSR2,KMT2C,CDHR3,TIMM44,YTHDF2,CCDC3,PAF1,GEMIN5,TMEM132B,EPN2,CSMD3,CLU,MTCH1,PIGN,CHST11,FN1,SCART1,TAF1,PCSK7,MED13L,EVPL,XPO7,PHGDH,NAMPT,TOX4,SIPA1L3,SEMA3D,PRF1,LRP3,AKAP11,VOPP1,ZBED4,JMJD1C,ZFP14,WBSCR22,WWC1,C11orf65,EIF2A,CORIN,AGAP1,HERPUD1,DNAH14,EXOC6,ATAD5,MYBBP1A,BICD1,KIAA0355,KIAA0754,FAT1,KIAA1328,TBL1X,TBCK,ZBTB24,DMXL2,ASH1L,PCNT,CELSR3,MMRN2,MYO7A,SMARCA4,COBLL1,DHX35,RIOK2,BRE,PPFIBP1,SNTG2,MET,VCL,C6orf89,MAML3,ACSL5,COL5A2,SFSWAP,METTL2A,ATXN1,R3HDM1,TOR1AIP2,DKC1,UBR4,ARMC4,DUSP19,FKBP5,DISP1,ARC,HEATR1,USP11,ECHDC1,SMG1,BCKDK,SULT1C2,DYM,PDE4B,DBF4,VPS45,CLSTN2,CHCHD10,ATF7IP,SEMA3E,CCDC7,SOGA1,ENOX1,GFM2,FAM49A,SFI1,MAN1A1,IL17RE,GART,SEC24C,KDELC1,TTC17,LDLRAD3,ERI3,DMRT1,KDM6B,PSPC1,ZNF324B,MARS,PHACTR2,LENG8,MEN1,EIF5B,ZNF407,TMEM187,CTIF,DAGLB,SERINC1,WDR35,MBD6,PREPL,NFKBIB,ZAK,MMP16 |
| 7.083e-05 | -9.56 | stomach-carcinoma-diffuse_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-diffuse_adenocarcinoma | 4562 | 660 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,ASCC1,THOC5,DCP1B,AARS2,NAT10,CACNA1H,SBF2,CSPP1,HLTF,CCNL2,NUP160,SYNJ1,LPAR3,AMBRA1,TOM1L1,PCDH7,C1orf159,PDZD2,ZFHX3,RABGAP1L,PDS5B,LYRM5,SRRM2,ZNRD1,FTSJ3,CDK6,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,PTPRM,AP4B1,KIF15,WDHD1,SHISA5,SLC9A5,ZNF266,RIOK1,VASH2,ZNF532,SLC25A26,HERC2,KHDRBS1,TRIO,NHS,KCNJ14,YARS2,ABCA7,SLC39A11,RSPRY1,SH2B3,RBM20,DDX56,UBE3A,CNST,DHX37,APLF,MCM5,WDR60,CCDC88C,CALN1,COQ3,AGL,PABPC1,PPA1,MYB,NOM1,FADS1,GATAD2B,GTF2H3,IFRD1,COL17A1,STAG1,KCNQ3,RB1CC1,IDH3G,RYR2,ST6GALNAC3,MBNL2,SRA1,ZNF783,IRS1,DYNC1H1,VPS13C,LRP1B,TASP1,KPNA1,GTF2A1,CLASRP,CNOT6,WDR33,PDLIM5,MB21D2,SRP14,COG5,SPRED2,SDSL,RAB11FIP4,ABCA3,DNM3,ZNF516,TRERF1,PAFAH1B1,BTBD2,MAB21L3,DDR2,CD99L2,MYH9,GRINA,SAFB2,ABCA12,ACD,SETD5,FMNL1,WAC,MGLL,ZC3H3,DENND1A,KMT2D,ARHGEF10,ADAM32,PCNXL2,TTC28,DSP,FKBP3,MAT2A,FGFR1,ZFAND3,PES1,ELP2,ASTN2,POLR3E,CAMKMT,WDR7,HOXA3,BRCC3,ZBTB11,LAMA5,METTL2B,YEATS2,LRCH1,XPC,ATG2B,PSMF1,KRI1,ACAP3,UNC13A,ACOT11,ANXA5,LTN1,ACTR3B,C15orf41,SOX6,HNRNPM,LYPLA2,SPTAN1,DIS3L2,VPS37A,ARHGAP39,ZC3H18,NXN,MRPS10,PPIP5K2,ETFDH,SRCAP,NSD1,BAZ2B,PXDN,PLPPR2,PTPN4,AEN,PSAP,SORCS2,MTMR1,DOCK6,KDM4C,PPARGC1B,TFIP11,RNF43,TTI1,TMEM132A,SEC16A,MAP2K3,ARHGAP18,ANKRD11,HKR1,TRIML2,UBAP2L,ETV1,CDC37,VPS13B,FLNC,BAZ2A,SKIV2L2,KATNAL1,ANK2,SUMO3,FLVCR1,ZNF91,CRYBG3,KIF16B,BSN,MSRA,INSIG1,TP53BP1,CHD3,TECPR2,SGSM2,MAGI1,USP15,CTU2,OXNAD1,ITFG1,ITPRIP,MAPK8IP3,DNAH1,RNF40,ZNF358,ABCA5,CEP290,PDE10A,VAPB,TIMELESS,SYNJ2,GMDS,ALDH18A1,LAMC1,KTN1-AS1,CRADD,IFT43,SETD2,WDR25,OBSCN,ZNFX1,TRAPPC6B,NR2F1,VAC14,PGD,GRIK4,FAM135A,DNAH17,HMBS,GGT7,SH3PXD2A,USP7,SART1,ID1,PAPD4,ARID2,RPS29,NTSR1,LAGE3,SSBP2,DENND3,RADIL,TNKS1BP1,SEMA6A,PELP1,CAD,UBR1,DNAJB6,FSIP2,ANKRD24,ZFP37,MYH15,ANO8,CORO1A,AKNAD1,AHCYL1,PRMT3,CTC1,SOBP,TLCD1,KAT8,WDR36,SSFA2,THSD4,CPOX,VIM,AKAP13,NHSL1,NUP214,ARL5B,BTBD11,SMAD3,SLC30A3,KLF4,CLEC16A,ITGA2,TSSC1,NFASC,PPIL3,PARD3,ZNF507,DMGDH,ESCO1,AUH,MAP3K13,C14orf159,FOXP1,CSNK1A1,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,CWC27,PRICKLE2,SELT,CPNE7,C12orf4,HSD17B12,ADAMTSL3,LRRIQ1,PLAC8L1,TEX14,PEAR1,FERMT2,ARHGEF12,GPNMB,POLR3A,ZRANB3,TPD52L2,NOL10,CSRNP1,BCAS3,MSH3,EIF2S1,FNTB,RPS6KC1,GCSH,ZNF292,LRP5L,UBR5,LPIN1,GIPR,EXOC1,SUCLG2,RNF111,ME1,SPAG6,TBC1D8,DPF3,SEMA3F,ZDHHC14,SON,DENND4A,MAK16,SPOP,GZF1,DDAH2,TRRAP,CCNT1,LSM14A,NSMCE1,GREB1L,DNAH2,TNFRSF10D,NMD3,EFNB2,DROSHA,CELSR1,LARS2,TATDN3,OPHN1,CCDC47,TGFBR2,CD226,MTUS1,TECTA,NAV1,ENTPD5,SLC7A11,NOVA2,ASAP1,SCAF1,COPS3,VWDE,PIGG,GTF3C3,LPCAT1,PRPS1,SCAF11,PRIM2,SYNGAP1,PCCA,RAP1B,PTPN12,TTYH2,ARID1A,TPRA1,EHBP1,MTR,PHF6,LYRM7,ATP9B,DAGLA,KIDINS220,ALKBH3,NSF,VCAN,SPEN,ZZEF1,ZCCHC6,SQLE,CNDP2,MACROD1,DHCR7,SMYD3,RTTN,PTCD2,TBKBP1,AMOTL1,TRPM2,BIRC6,URB2,HFM1,C1QTNF7,TMEM104,SPATS2L,PTPRG,FLNB,PDE3A,PAIP2,TERF2IP,ZNF827,ASNS,TMEM184A,SLX4,PPID,NBEA,SERPINH1,KMT2A,PLEKHA4,CDK12,NAA35,PREX1,KIAA1586,SATB2,MARCH6,MED16,SETD7,DHX57,BAZ1A,HTR7,ACP1,IFT140,TRAF3,KLHDC4,MDN1,MID1,NCOR2,BRAF,TTC27,TCF3,NFX1,RTN4,MLH1,MON2,OPA1,GIGYF2,FOXO3,MAD2L2,PTRF,NISCH,COPS7B,NLGN3,DYNC2H1,LARP4B,C6orf163,SLC40A1,TTLL5,WDFY3,FZD3,WDR18,ADSL,PACS1,OASL,NOP58,SLC23A2,KLHL22,ZDHHC11,HELZ,ORC5,STX18,RNF138,SVIL,ATM,APAF1,BRWD3,ADK,IPO4,IMMP2L,PIGM,MVK,UBN1,NF1,ATRX,KIF5A,FANCD2,PPIL1,SIRT2,BCOR,STK33,DST,ZNF804A,THADA,YLPM1,ZNHIT6,ATG3,MYH3,GPATCH1,ZEB1,IPP,PCOLCE2,SLC27A5,NDUFA6,TRIM14,TRIP13,LONP1,LAMA4,GPM6A,VWCE,TFPI,KSR2,KMT2C,CDHR3,TIMM44,YTHDF2,CCDC3,PAF1,GEMIN5,TMEM132B,EPN2,CSMD3,CLU,MTCH1,PIGN,CHST11,FN1,SCART1,TAF1,PCSK7,MED13L,EVPL,XPO7,PHGDH,NAMPT,TOX4,SIPA1L3,SEMA3D,PRF1,LRP3,AKAP11,VOPP1,ZBED4,JMJD1C,ZFP14,WBSCR22,WWC1,C11orf65,EIF2A,CORIN,AGAP1,HERPUD1,DNAH14,EXOC6,ATAD5,MYBBP1A,BICD1,KIAA0355,KIAA0754,FAT1,KIAA1328,TBL1X,TBCK,ZBTB24,DMXL2,ASH1L,PCNT,CELSR3,MMRN2,MYO7A,SMARCA4,COBLL1,DHX35,RIOK2,BRE,PPFIBP1,SNTG2,MET,VCL,C6orf89,MAML3,ACSL5,COL5A2,SFSWAP,METTL2A,ATXN1,R3HDM1,TOR1AIP2,DKC1,UBR4,ARMC4,DUSP19,FKBP5,DISP1,ARC,HEATR1,USP11,ECHDC1,SMG1,BCKDK,SULT1C2,DYM,PDE4B,DBF4,VPS45,CLSTN2,CHCHD10,ATF7IP,SEMA3E,CCDC7,SOGA1,ENOX1,GFM2,FAM49A,SFI1,MAN1A1,IL17RE,GART,SEC24C,KDELC1,TTC17,LDLRAD3,ERI3,DMRT1,KDM6B,PSPC1,ZNF324B,MARS,PHACTR2,LENG8,MEN1,EIF5B,ZNF407,TMEM187,CTIF,DAGLB,SERINC1,WDR35,MBD6,PREPL,NFKBIB,ZAK,MMP16 |
| 7.089e-05 | -9.55 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | 197 | 45 | 17758 | 2279 |
UTP14A,LARS2,HSD17B10,NAT10,CSNK2A1,NDUFB3,CAD,ANAPC1,DDX56,DUS4L,NOP16,ATG3,SLC39A7,ETF1,NOC3L,AVEN,LONP1,C12orf4,MYB,TMPO,ACSL5,NARS2,FAM98A,MPP6,PPAT,WDR18,PSMG1,MARS,RANGAP1,BRCA1,DKC1,UBE2K,CYB5B,RBM28,WARS,EPRS,POLE2,TIMM17A,PTRH2,SLC25A11,RWDD2B,HEATR1,MED20,RBPJ,PFDN2 |
| 7.153e-05 | -9.55 | regulation of chromosome organization | biological process | GO:0033044 | 241 | 53 | 16441 | 2138 |
ATRX,SUPT6H,CAMK1,CSNK2A1,MAP1S,BCOR,RPS6KA5,UBR5,MAD2L2,KDM1A,SKI,SMARCB1,TERF2IP,RNF40,TADA3,SNW1,ANAPC1,SLX4,ACD,YLPM1,MYC,ANAPC11,ANAPC10,MAD1L1,CTR9,KMT2A,CTC1,TERF2,MYB,PAXBP1,WDR61,KDM5A,TEX14,WDHD1,HDAC8,BRCA1,SETD7,DKC1,UBE2E1,SNCA,PAF1,CAMK2D,NSD1,KLHL22,CDC16,CDK9,NSMCE2,SET,ATG7,ATM,NCOR1,ANAPC4,PKIB |
| 7.163e-05 | -9.54 | RBBP5 (retinoblastoma binding protein 5) | protein interactions | 5929 | 62 | 21 | 16036 | 2270 |
KDM6B,KAT8,CUL4A,KMT2D,TUBA1A,SETD1B,PPARG,MEF2D,MEN1,KMT2C,CDC73,KDM4B,SMARCC1,ZBTB8OS,KANSL1,SENP3,WDR33,KMT2A,HCFC2,EMSY,MYB |
| 7.210e-05 | -9.54 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 280 | 59 | 17758 | 2279 |
LYRM4,RBM33,DDX19A,MEX3A,C1orf226,LAGE3,MED13L,TUBB6,BHLHE40,PSMF1,MAD2L2,NOS1AP,FLNB,IGSF1,CHN1,PRKD3,HR,LYPLAL1,PMAIP1,MYC,MED24,GREB1,PRMT5,PNPLA3,NRIP1,POLR1E,PNMA1,SAP30,FDFT1,MYB,MSI2,SIK3,APEX1,SIGMAR1,HAUS6,KRTCAP3,NLN,PSMG1,SEMA3F,APTX,SMPDL3B,GLS,IRS1,RBBP8,ELP2,PDLIM1,EHMT2,RPL28,VCAN,ITGA2,HSPB8,LARGE,BBIP1,FKBP5,PUS1,TBL1X,DHCR7,PKIB,MAPT |
| 7.274e-05 | -9.53 | MODULE_61 | MSigDB lists | MODULE_61 | 49 | 17 | 17758 | 2279 |
TUBA1A,APEX1,CDK4,ADSL,IMPDH2,ODC1,HDDC2,GART,GADD45A,MYC,SHMT2,UMPS,RAN,ADK,BLMH,ANGPT2,TOP1 |
| 7.303e-05 | -9.52 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_UP | 180 | 42 | 17758 | 2279 |
PTCD2,NDUFA5,URB2,MRPL10,SLC25A12,PDCD7,CIAPIN1,ZSCAN5A,FLAD1,CAD,HVCN1,ZNF561,SUV39H2,YLPM1,SAMD13,POLE3,PRADC1,PRMT5,ZNF460,POLR1E,LRRC20,EXOSC2,DDX28,FAM172A,APEX1,CRADD,PPAT,KIAA0586,IMPDH2,NAPEPLD,MRPL36,PEX1,FBXO21,SRP68,CCDC85B,SLC25A11,RUNX1,HMBS,PUS1,TSEN2,NUDT22,HRH1 |
| 7.329e-05 | -9.52 | XPC (xeroderma pigmentosum, complementation group C) | protein interactions | 7508 | 45 | 17 | 16036 | 2270 |
USP7,POLB,XPC,SIRT6,ZNF512B,UBC,CHAF1A,RPA1,SMARCB1,APLF,BANF1,H2AFX,ZCCHC6,RNF111,GTF2H1,ATM,USP11 |
| 7.340e-05 | -9.52 | WANG_LMO4_TARGETS_DN | MSigDB lists | WANG_LMO4_TARGETS_DN | 329 | 67 | 17758 | 2279 |
POLB,CGN,FEZ2,CCDC58,NDUFAF2,SPRYD7,PLRG1,COBLL1,UBR5,FDX1,EXOC1,BCAS2,GPR87,BCAP29,CSGALNACT2,PTPRK,EVL,SLC3A2,MTIF2,EXOC6B,EHMT1,GSTCD,KRTCAP2,DKC1,DLST,DDX60,SAP30BP,UBR4,ZNF622,ELP2,PAM,HSPB8,SRFBP1,LYRM2,CWC27,RDX,GTF3C3,TTC17,PRMT5,TOP1,TRNP1,KCNQ3,RB1CC1,ABCF2,MAPK1IP1L,ZNFX1,FAM126B,ZNF407,SRA1,EIF5B,SLC26A11,PIK3CB,PHF6,EXOC6,RDH11,DYNC1H1,BAZ2B,DAGLB,GADD45A,SRP68,EXOC4,PURB,RBM26,PSAP,GPATCH4,COG5,LRRC41 |
| 7.410e-05 | -9.51 | DNA recombination | biological process | GO:0006310 | 259 | 56 | 16441 | 2138 |
HERC2,POLB,ATRX,TCF3,HFM1,FAN1,MLH1,RMI1,MCM9,RPAIN,SFR1,ABL1,SLX4,BRE,ZSWIM7,UCHL5,XRCC2,ATRIP,TIMELESS,MSH4,SPIDR,TRIP13,RFC4,RFC3,APEX1,PRIM2,SIRT6,POLA1,TSN,PSMC3IP,TOP3A,LIG4,HIST1H4J,BRCA1,UBC,RPA1,RAD54B,EXO1,RBBP8,BRCA2,PALB2,POLE2,TP53BP1,NSMCE1,NSMCE2,MSH3,H2AFX,RAD51B,ATM,RBPJ,EME1,NFRKB,CCNB1IP1,BRCC3,XRCC4,SMG1 |
| 7.430e-05 | -9.51 | Cholesterol biosynthesis | WikiPathways | WP197 | 17 | 9 | 4455 | 564 |
LSS,IDI1,MVK,SREBF2,FDPS,SQLE,DHCR7,HMGCR,FDFT1 |
| 7.485e-05 | -9.50 | nucleotidyltransferase activity | molecular function | GO:0016779 | 122 | 32 | 16491 | 2164 |
CTU2,POLB,PAPD4,POLR1A,FLAD1,ABL1,POLR3D,ISPD,POLR3B,POLR1B,POLE3,ZNRD1,POLR1E,PRIM2,GPHN,POLK,POLA1,DKC1,OASL,POLG2,POLR3A,POLR2A,POLR3G,TAMM41,MYBBP1A,POLE2,POLR3E,ZCCHC6,CRCP,MED20,EIF2B3,POLR1C |
| 7.504e-05 | -9.50 | LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 123169 | 37 | 15 | 16036 | 2270 |
PAF1,DCTN3,SUPT4H1,WDR61,CCNT1,ZC3H18,CTR9,CSNK2A1,CHD2,SUPT5H,KMT2A,CDC73,FLNB,POLR2A,UBE2E1 |
| 7.578e-05 | -9.49 | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | 186 | 43 | 17758 | 2279 |
TNIK,ASH1L,PHF3,TRIM16,XPC,ARFIP2,HMOX2,TNKS1BP1,PELP1,PAG1,NOP56,ATXN7L1,RNFT2,DDX56,CNST,THAP4,MAD1L1,MAP3K14,SLC25A23,DIS3L2,MARCH9,VOPP1,DDX24,IL11RA,ARID5B,KIAA0586,LRRC8A,ADSL,PCNXL2,PHACTR2,PACS1,SERGEF,ZNF251,NCDN,KLHL22,CHD3,GLG1,USP20,ZFP90,NFRKB,MDN1,RUNX1,RNF214 |
| 7.673e-05 | -9.48 | functioning | COSMIC cancer mutations | functioning | 1876 | 294 | 17775 | 2278 |
MYCBP2,CDCP1,CACNA1H,NBEAL1,LPIN1,CIAPIN1,PABPC4,MGA,PCDH7,GIPR,PDZD2,IKZF5,PDS5B,VPS52,ZNF646,PTPRM,EHMT1,KIF15,WDHD1,ZDHHC14,DDX60,RBM28,MAK16,PLCXD2,STOML2,AHNAK,TRRAP,LSM14A,CCNT1,SEMA3C,CCNB1IP1,WDR66,SPOCK3,HERC2,ANKRD17,ZHX3,ST6GAL1,SIRT7,TRIO,DPM3,PRPF39,TGFBR2,CDC73,ANXA10,MTUS1,RBM20,KIAA1671,MED24,MYB,SIK3,RREB1,MYO10,RDH10,RYR2,PTPN12,EVI5,USP46,ANGPTL4,ABCF1,NCDN,DYNC1H1,ZNF425,VPS13C,MTHFD2,KPNA1,KIDINS220,EHMT2,PDLIM1,TRAP1,D2HGDH,ZCCHC6,PEX13,CNOT6,KIAA0196,ARHGAP10,ZFHX2,SYT17,BIRC6,MYH9,PTPRG,TRIM66,RPGRIP1L,PDE3A,TERF2IP,ABCA12,GLYR1,LPIN2,MRPS27,C16orf58,NBEA,TTC3,KMT2A,CDK12,CASP8AP2,LYST,ZCCHC14,KMT2D,GON4L,PCNXL2,GNL1,MARCH6,GSTCD,DSP,STK10,DCBLD2,GNG2,DNTTIP1,KDM4B,PAM,IFT140,TRAF3,LAMA5,XPC,NFX1,FARS2,KIF5C,RTN4,MON2,GDPD5,RSRC1,TMCO6,ZNF239,SUV39H2,CFDP1,HARS2,FBXL19,DIS3L2,FAM120B,DDHD1,C19orf43,PPIP5K2,ECH1,CCDC150,SRCAP,INF2,ZNF155,HERC1,SLCO5A1,PTPN4,SVIL,MTMR1,CUL7,FEM1C,ATRX,GPBP1L1,POLR1A,PPARGC1B,KIF5A,PLOD1,RNF43,BCOR,TMEM132A,COX10,BIRC2,SNAPC4,FRRS1,DHX33,MARVELD2,ANAPC11,ANKRD11,GPATCH1,HYAL1,RAN,NDUFA6,ZMYM2,FAM184A,DSC3,FMNL3,SLC3A2,MIOS,ZNF195,ANK2,GDPD1,VWCE,HDAC8,MTHFD1L,KMT2C,SERGEF,CHAF1A,TAF9B,KIF16B,TCF7L1,TRMT5,TP53BP1,CC2D1B,RLTPR,EME1,TAF1,SEC24D,ALG8,EVPL,XPO7,DNAH1,DOPEY1,KIAA1958,ELL,MCAM,ZNF354A,CEP290,PRF1,AKAP11,ATP6V0D1,ZNF629,HSD17B14,RANBP6,CAMKK2,ZNFX1,DNAH14,TBC1D2,NAP1L5,SYCP2L,GRIK4,UBAP2,ITPRIPL1,KIAA0355,FAT1,HK2,PPP1R12B,DTD1,ZFP90,NR2C2AP,ZBTB24,BCCIP,ASH1L,ARID2,SMARCA4,SLC9B2,TNKS1BP1,PPP1R9A,GBF1,ZNF121,SEMA6A,SBDS,ZSCAN5A,VPS18,CAD,GRIN2C,PPFIBP1,AKNAD1,ITGAX,CTC1,SOBP,SEC24A,KDM3B,ANKRD33B,CPOX,VIM,NHSL1,ENC1,NUP214,UBR4,WARS,IFT81,DUS3L,ADNP,ARNTL,INTS9,PRRT3,NFRKB,PUS1,USP11,ZNF507,DNAJC2,AUH,MAP3K13,CLSTN2,C14orf159,SEMA3E,ENOX1,FOXP1,ANKRD54,GART,NDUFV1,SEC24C,IFIT5,STC2,TANK,PRICKLE2,PCK2,FBL,ABCF2,PSMC3IP,PPP1R21,ARHGAP32,MEN1,ZNF407,NEU1,RERE,GADD45A,GPC2,SRBD1,MPP7,BCAS3,ITGB4 |
| 7.673e-05 | -9.48 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1876 | 294 | 17775 | 2278 |
MYCBP2,CDCP1,CACNA1H,NBEAL1,LPIN1,CIAPIN1,PABPC4,MGA,PCDH7,GIPR,PDZD2,IKZF5,PDS5B,VPS52,ZNF646,PTPRM,EHMT1,KIF15,WDHD1,ZDHHC14,DDX60,RBM28,MAK16,PLCXD2,STOML2,AHNAK,TRRAP,LSM14A,CCNT1,SEMA3C,CCNB1IP1,WDR66,SPOCK3,HERC2,ANKRD17,ZHX3,ST6GAL1,SIRT7,TRIO,DPM3,PRPF39,TGFBR2,CDC73,ANXA10,MTUS1,RBM20,KIAA1671,MED24,MYB,SIK3,RREB1,MYO10,RDH10,RYR2,PTPN12,EVI5,USP46,ANGPTL4,ABCF1,NCDN,DYNC1H1,ZNF425,VPS13C,MTHFD2,KPNA1,KIDINS220,EHMT2,PDLIM1,TRAP1,D2HGDH,ZCCHC6,PEX13,CNOT6,KIAA0196,ARHGAP10,ZFHX2,SYT17,BIRC6,MYH9,PTPRG,TRIM66,RPGRIP1L,PDE3A,TERF2IP,ABCA12,GLYR1,LPIN2,MRPS27,C16orf58,NBEA,TTC3,KMT2A,CDK12,CASP8AP2,LYST,ZCCHC14,KMT2D,GON4L,PCNXL2,GNL1,MARCH6,GSTCD,DSP,STK10,DCBLD2,GNG2,DNTTIP1,KDM4B,PAM,IFT140,TRAF3,LAMA5,XPC,NFX1,FARS2,KIF5C,RTN4,MON2,GDPD5,RSRC1,TMCO6,ZNF239,SUV39H2,CFDP1,HARS2,FBXL19,DIS3L2,FAM120B,DDHD1,C19orf43,PPIP5K2,ECH1,CCDC150,SRCAP,INF2,ZNF155,HERC1,SLCO5A1,PTPN4,SVIL,MTMR1,CUL7,FEM1C,ATRX,GPBP1L1,POLR1A,PPARGC1B,KIF5A,PLOD1,RNF43,BCOR,TMEM132A,COX10,BIRC2,SNAPC4,FRRS1,DHX33,MARVELD2,ANAPC11,ANKRD11,GPATCH1,HYAL1,RAN,NDUFA6,ZMYM2,FAM184A,DSC3,FMNL3,SLC3A2,MIOS,ZNF195,ANK2,GDPD1,VWCE,HDAC8,MTHFD1L,KMT2C,SERGEF,CHAF1A,TAF9B,KIF16B,TCF7L1,TRMT5,TP53BP1,CC2D1B,RLTPR,EME1,TAF1,SEC24D,ALG8,EVPL,XPO7,DNAH1,DOPEY1,KIAA1958,ELL,MCAM,ZNF354A,CEP290,PRF1,AKAP11,ATP6V0D1,ZNF629,HSD17B14,RANBP6,CAMKK2,ZNFX1,DNAH14,TBC1D2,NAP1L5,SYCP2L,GRIK4,UBAP2,ITPRIPL1,KIAA0355,FAT1,HK2,PPP1R12B,DTD1,ZFP90,NR2C2AP,ZBTB24,BCCIP,ASH1L,ARID2,SMARCA4,SLC9B2,TNKS1BP1,PPP1R9A,GBF1,ZNF121,SEMA6A,SBDS,ZSCAN5A,VPS18,CAD,GRIN2C,PPFIBP1,AKNAD1,ITGAX,CTC1,SOBP,SEC24A,KDM3B,ANKRD33B,CPOX,VIM,NHSL1,ENC1,NUP214,UBR4,WARS,IFT81,DUS3L,ADNP,ARNTL,INTS9,PRRT3,NFRKB,PUS1,USP11,ZNF507,DNAJC2,AUH,MAP3K13,CLSTN2,C14orf159,SEMA3E,ENOX1,FOXP1,ANKRD54,GART,NDUFV1,SEC24C,IFIT5,STC2,TANK,PRICKLE2,PCK2,FBL,ABCF2,PSMC3IP,PPP1R21,ARHGAP32,MEN1,ZNF407,NEU1,RERE,GADD45A,GPC2,SRBD1,MPP7,BCAS3,ITGB4 |
| 7.748e-05 | -9.47 | JmjC_dom | interpro domains | IPR003347 | 32 | 13 | 18293 | 2341 |
KDM6B,KDM3B,HR,KDM5B,KDM4B,KDM2A,KDM5A,HSPBAP1,JMJD1C,MINA,JMJD6,KDM5C,KDM4C |
| 7.748e-05 | -9.47 | SNF2_N | interpro domains | IPR000330 | 32 | 13 | 18293 | 2341 |
CHD7,CHD9,SRCAP,EP400,CHD3,ATRX,SMARCAD1,SMARCA4,CHD2,HLTF,CHD5,ZRANB3,RAD54B |
| 7.807e-05 | -9.46 | RNA polymerase II core binding | molecular function | GO:0000993 | 20 | 10 | 16491 | 2164 |
PAF1,ELP2,ELP3,AGO2,WAC,ZNF326,CTR9,IKBKAP,SMYD3,CDC73 |
| 7.829e-05 | -9.46 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 192 | 44 | 17758 | 2279 |
POLB,ACTG1,ALG8,PIK3R4,DENR,RIOK2,SRPRB,RPP30,ADH5,UBE3A,INTS7,ATG3,UCHL5,XRCC2,SLC39A7,ETF1,GSTA4,ZNF148,GTF3C3,CD44,MYB,CLK2,CHD9,TSN,HSPA5,TPM4,RAP1GDS1,SUMO3,LIG4,VIM,EXOG,ENC1,ST3GAL5,POLR2A,RAD54B,TPD52L2,TCF7L1,NME7,TIMM17A,CNOT6,PTP4A2,SMYD3,CEP170,NIT1 |
| 7.829e-05 | -9.46 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | 192 | 44 | 17758 | 2279 |
ZNF254,ARHGAP26,PCNT,PRDX6,ACTR3,LAGE3,NAT10,HLTF,PRPF39,RMI1,MBNL1,MFHAS1,KDM1A,LPIN1,FARSA,ASAP1,DNAJB6,MCM5,RABGAP1L,DCTN4,ZNF85,PEG10,HNRNPM,SERBP1,TOP1,SPTAN1,GARS,ZNF195,KLHL23,PPAT,MARCKSL1,USP10,PNN,TCTN1,ABCF1,SKIL,BAZ2B,SERF2,CHD3,FDPS,SCARB1,PDCD11,YEATS2,SLC43A1 |
| 7.835e-05 | -9.45 | CTTTGCA,MIR-527 | MSigDB lists | CTTTGCA,MIR-527 | 227 | 50 | 17758 | 2279 |
EFNB2,TCF12,CADM4,CHST11,RFX1,PAX2,ACTR3,WDR26,PRKCA,MBNL1,RAP1A,KDM2A,NCKIPSD,NBEA,RNF111,HARS2,MAP3K14,SAMD4A,SRPK2,PFKFB4,HMBOX1,ANTXR2,CHD9,AEBP2,TEAD1,PTPRM,KCNMA1,RAP1GAP2,ATXN1,RSBN1,SATB2,PNN,MEF2D,SLC35D1,PLCB1,MBNL2,PHF6,KPNA3,GADD45A,PMEPA1,L3MBTL3,SPEN,SET,RPS6KB1,NFASC,GGT7,KIF1B,ZNF532,TNRC6A,MEF2C |
| 7.867e-05 | -9.45 | enzyme binding | molecular function | GO:0019899 | 1647 | 267 | 16491 | 2164 |
GNB3,POLB,CUL4A,PRDX6,ACTG1,PRKCSH,SBF2,CCNL2,PRKCA,AMBRA1,NOS1AP,TOM1L1,SKI,EXOC1,ZFHX3,NEK6,RABGAP1L,SNU13,AKAP12,WDHD1,DCUN1D5,SH3GL1,SPOP,STOML2,RBSN,BRCA2,RAD18,DIRAS1,PTPN14,HERC2,CDC42EP2,TRIP6,EGR1,JUP,TRIO,PARN,CD226,CDC73,NDUFS7,PRKCE,HR,CNST,CACNB2,ZNF326,ANP32B,MAP3K12,FMNL2,CAV2,ANGPT2,HMGCR,ZNF675,SYNGAP1,KCNQ3,RB1CC1,POLA1,PCCA,RAPGEF4,RYR2,EVI5,TRIM37,PLCB1,PHF6,ARIH2,IRS1,CAT,EPRS,NSF,TRAP1,HIF1A,VCAN,NCOR1,PDLIM5,SMYD3,SGSM3,SPRED2,DNM3,RAB11FIP4,PAFAH1B1,AP1B1,HSPA1A,NOP56,ACD,SHC1,FMNL1,WAC,NBEA,PREX1,DLG4,ATP6V0A1,MEF2D,MARCH6,DSP,ERC1,SNCA,CAMK2D,ELP2,DNAJA3,H2AFX,RPS6KB1,TRAF3,ANXA2,MID1,MAPT,NCOR2,BRAF,SCAMP3,C10orf2,TCF3,GAS6,TRIM22,NOL3,IKBKAP,FOXO3,MAD2L2,NEDD4,ABL1,ANXA5,RDX,YBX3,ERRFI1,PXN,LDHA,IL6R,PTK2,UBE2K,PDE3B,NOP58,POLR2A,UBC,TRIB3,INF2,STX1A,RNF138,IGBP1,ANAPC4,KDM4C,IPO4,CUL7,KMT2E,FANCD2,SIRT2,BCOR,SCAF8,MAP2K3,RAP1A,ECM1,ZNHIT6,ATG3,ZMYM2,LONP1,PRKACB,PTPRK,CDC37,FMNL3,PPARG,ANK2,HSPA5,COTL1,BRCA1,CAV1,KCNH2,KIF16B,PAF1,HLCS,TOM1L2,GATA6,SUFU,PER1,ADAM9,SGSM2,DPP4,CLU,SLC12A7,TTN,STX8,FOXO1,FN1,STXBP6,UBXN1,MAPK8IP3,SMAD7,NKD2,SMG7,XPO7,RNF40,ELL,VAPB,CTR9,NRIP1,AKAP11,CRADD,ELP3,XPO5,WWC1,PRDM1,SUPT5H,TCF7L2,SPAG9,BICD1,EXOC4,RRAGA,PPP1R12B,BRSK2,PRKAR2A,N4BP2L2,DMXL2,USP7,CYLD,SLC2A1,RIPK1,SMARCA4,PPP2R2A,CSTA,TNKS1BP1,KDM1A,CAD,RRN3,CAMTA2,SOCS1,CCDC50,IKBKB,FHIT,MET,TSPAN14,VCL,IPO11,CASP10,KAT8,AKAP8L,RAB7A,TOR1AIP2,AKAP13,SMAD3,RANBP2,KLF4,DUSP19,NFRKB,TSPAN5,PARD3,UNC13D,KIZ,HM13,MAP3K13,DYM,AGO2,ARFIP2,ZNF346,SFI1,IQGAP2,PRKCH,PTPN2,PEX7,CTNNBL1,STC2,TANK,FBL,MICAL3,PPP1R9B,PPP1R21,TEX14,RANGAP1,HSPA1B,MFN2,CUL2,MSH3,BCAS3,XPO6 |
| 7.868e-05 | -9.45 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | protein interactions | 7307 | 114 | 32 | 16036 | 2270 |
SART1,CUL7,FN1,ZCCHC8,SF3A3,JMJD6,PHGDH,NOP56,DDX56,SRSF2,BCAS2,MCM5,RNF2,RAN,FBL,SRRM2,PABPC1,FTSJ3,HNRNPM,CLK2,SRPK2,PRPF19,SF3A1,SNU13,FRA10AC1,SON,NOP58,TOE1,SYNCRIP,ZRANB2,PRPF4,PSAP |
| 7.899e-05 | -9.45 | RPA3 (replication protein A3) | protein interactions | 6119 | 374 | 80 | 16036 | 2270 |
USP7,RBFOX2,MYH9,HLTF,AP1B1,PELP1,HNRNPA3,KDM1A,PABPC4,BCAS2,ATRIP,SEH1L,TMPO,SF3A1,PRPF19,RFC4,RFC3,LIMA1,SKIV2L2,RAB7A,HSPA5,WDHD1,CAV1,MCM2,DSP,RAB10,YTHDF2,GEMIN5,DDX3X,DNTTIP1,AHNAK,HNRNPR,FUS,ANXA2,ZNF598,BAG1,TMEM33,HERC2,SCAMP3,ZCCHC8,KHDRBS1,UBXN1,RTN4,CSNK1A1,CLINT1,RMI1,EIF2S2,LTN1,POLR1B,GEMIN4,CELF1,FBL,PABPC1,ATP6V0D1,HNRNPM,TERF2,SPTAN1,MTHFD1,MSI2,GTF2H3,APEX1,POLA1,TOP3A,LDHA,IMPDH2,SYMPK,UBC,RPA1,EPRS,TSR1,SRBD1,SYNCRIP,MSH3,EIF2S1,PURB,C7orf50,RBM26,KIAA0196,WDR33,NAPA |
| 7.924e-05 | -9.44 | ENK_UV_RESPONSE_KERATINOCYTE_DN | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_DN | 481 | 91 | 17758 | 2279 |
USP7,ID1,ATP6V1A,ATRX,PAFAH1B1,RBFOX2,ACTR3,SLC2A1,LPCAT3,UBR5,BIRC2,PCDH7,RPP30,RNF2,ZNF148,ZMYM2,TRIP13,LYST,PCGF3,TRIM13,EIF3J,CPOX,CUX1,GMFB,VSNL1,PCMT1,PSMG1,SEMA3F,MCL1,DKC1,CXADR,RANBP2,RBBP8,TP53BP1,HNRNPR,LUC7L3,ARL6IP5,TNFRSF1A,CTAGE5,SEMA3C,FKBP5,PRPF4,TBXA2R,NOLC1,BLMH,BMI1,TROVE2,AUH,MCM6,IKBKAP,BHLHE40,TGFBR2,CSNK1A1,FOXO3,MBNL1,IGF2BP3,ADH5,ANXA7,ATXN2,MBD2,RDX,CD44,CNOT4,AGL,AKAP11,RABEPK,FDFT1,MTHFD1,SCAF11,CAMKK2,IFNGR2,CRADD,CRIM1,MYO10,KDM5A,CYB5B,TMEM187,DKK1,IRS1,EPRS,RARS,FAT1,SVIL,SQLE,FNTB,SLC16A1,UMPS,PTP4A2,GCSH,KAT6A,COG5 |
| 8.035e-05 | -9.43 | cellular protein metabolic process | biological process | GO:0044267 | 3550 | 530 | 16441 | 2138 |
PTP4A1,DPH1,AARS2,MRPL10,HLTF,NUP160,PABPC4,TOM1L1,NEK6,PMAIP1,FNIP2,KDM5C,FXN,CDK6,PPM1K,EIF4E3,NRAS,KLHL23,PTPRM,EHMT1,MSRB3,DCUN1D5,STOML2,DDX3X,BRCA2,SSU72,RAD18,RIOK1,MEF2C,CARS,HERC2,EP400,SLK,TRIO,SIRT7,PIK3R4,CDC73,YARS2,ABCA7,UBE3A,EIF2S2,MED24,MRPL21,PRMT5,MAP3K12,PABPC1,PPA1,PEA15,GTF2H3,TIMM8B,ALG6,WDR61,STAG1,RB1CC1,EIF4A2,USP10,ATAT1,ST6GALNAC3,TRIM37,ABCF1,USP46,IRS1,RPL28,EHMT2,CDK9,SENP3,SRP14,C18orf25,MAP2K5,ABCA3,PDK4,DDR2,TUBB6,NUP43,ST3GAL6,UBL5,PRKD3,WAC,PXK,KMT2D,GARS,STAMBP,EIF3J,KCNH3,DSP,FKBP3,FGFR1,FBXL5,CDC16,NSMCE2,HIPK2,CAMKMT,RPS6KB1,BRCC3,YEATS2,TRIM36,HMGA2,XPC,TRAK1,JMJD6,GAS6,TRIM22,TGFB2,RSRC1,PSMF1,POM121,TTLL11,TADA3,NPRL2,GATC,SUV39H2,LTN1,FBXL19,RPL22L1,LYPLA2,SPTAN1,FGF9,VPS37A,USP42,MRPS10,UBE2K,UBC,MRPL36,ANXA1,RPA1,OXSR1,TRIB3,NSD1,SRCAP,RARS,STX1A,HERC1,SRD5A3,PTPN4,BMP4,MTMR1,ANAPC4,KDM4C,CUL7,TRIM16,MFGE8,HECTD3,CSNK2A1,RNF43,SEC16A,BIRC2,MAP2K3,ABL2,COPS4,PHKA1,TRIML2,POLE3,PTPRK,RBCK1,ATF4,GCNT2,HARS,BAZ2A,CDK4,HSPA5,MED27,GMFB,COL4A3BP,ATG12,SUMO3,BRCA1,KCNH2,DYRK1B,MSRA,EEFSEC,PER1,SOCS4,PPP3CC,USP15,CHMP4C,CTU2,SARS,TTN,FOXO1,CLK1,MAPK8IP3,LAMTOR3,SMAD7,RNF40,PPIL2,GTF2H1,CTR9,SYNJ2,LRSAM1,WARS2,TRAPPC9,CAMKK2,USP49,SETD2,OBSCN,MEX3B,TRAPPC6B,ATXN7,SPAG9,IRAK2,CASS4,HMBS,PTP4A2,BRSK2,NAPA,RNF114,USP7,MPI,CYLD,RPS29,PPP2R2A,RIPK1,RNF24,DENND3,KDM1A,DENR,CAD,JAG1,NUP133,GRIN2C,UBR1,IKBKB,ZDHHC6,ETF1,RNF2,PRMT3,PRPF19,SEC24A,KAT8,TUBA1A,NARS,RAB7A,AKAP13,ENC1,NUP214,EIF3H,USP36,RANBP2,TIMM17A,ATG7,MED20,EIF2B3,PPIL3,ESCO1,MINK1,MAP3K13,AGO2,VARS,CSNK1A1,PTPN2,ADH5,CWC27,HIST2H3D,SELT,FBXO31,SMARCAD1,TEX14,HIST1H4J,NEU1,EIF2S1,FNTB,USP20,TAF12,RPS6KC1,MYCBP2,CUL4A,PRKCSH,PRKAB2,PRKCA,UBR5,AARS,EXOC1,RPS16,RNF111,DPH6,FUT11,SEH1L,SETD1B,EYA3,TCEB3,ZDHHC14,DOT1L,SPOP,TRRAP,SH3RF1,CCNT1,NSMCE1,CCNB1IP1,BLMH,BMI1,SPOCK3,SPOCK2,PTPN14,WDR75,LARS2,ST6GAL1,DPM3,CCDC47,SSR4,TGFBR2,CHD5,IGF2BP3,PRKCE,FKBP1A,ENTPD5,USPL1,MYC,COPS3,PIGG,CNOT4,SIK3,SYNGAP1,ANAPC13,PTPN12,ARIH2,SEC31A,EPRS,NSF,UBAP1,SRP68,D2HGDH,RIOK3,MACROD1,MAP2K4,SMYD3,BIRC6,KLHL18,PTPRG,RING1,PHC2,ASNS,KDM2A,SHC1,PPID,UCHL5,MRPS27,SOCS6,TTC3,KMT2A,CDK12,BRD4,PDK1,MTIF2,PCMT1,DLG4,MARCH6,SETD7,SERP1,ERC1,STK10,SNCA,CAMK2D,FTSJ1,LARGE,ACP1,TRAF3,SETD6,XRCC4,SSH2,BRAF,B4GALT5,TCF3,FARS2,LIAS,IKBKAP,RPS6KA5,GIGYF2,NEDD4,ABL1,PMPCA,COPS7B,HARS2,MAP3K14,MBTPS2,CLK2,TTLL5,PXN,TBRG4,PTK2,GUF1,YIF1A,FBXO21,KLHL22,ZDHHC11,RNF138,ATM,PGAM5,DDIT3,LRRC41,STK4,KAT6A,IMMP2L,PIGM,EIF3C,FEM1C,KMT2E,NF1,PTPRA,RARS2,TRPM6,RCHY1,PLOD1,PPIL1,SIRT2,BCOR,STK33,PCYOX1L,SLC30A7,MRPS30,SRPRB,ANAPC1,KANSL1,CNIH3,ATG3,ANAPC11,ANAPC10,IPP,SLC35C2,YARS,GALNT18,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,TNK2,TRIM13,FBXW4,SIRT6,KSR2,HDAC8,CAV1,KMT2C,SGK2,ST3GAL5,TIMM44,PAF1,UBE3D,GATA6,HLCS,CTAGE5,ASB3,GALNT10,COPS6,DCAF5,FBXO45,PIGN,FN1,TAF1,SEC24D,UBXN1,ALG8,EVPL,TIMM10,RHBDD1,RNF141,P3H1,ISPD,ATP6V0D1,ELP3,PSMA1,EIF2A,TMEM241,UBE2E1,ISG15,HERPUD1,EXOC6,MGAT2,EXOC4,CDKAL1,TBL1X,PFDN2,TBCK,ASH1L,DLL4,PIGH,ARSJ,CSTA,PIBF1,RIOK2,FARSA,KCTD11,LYPLAL1,SOCS1,RPS6KL1,ADCK4,MET,AUP1,HTRA2,NARS2,PARP2,MRRF,EDEM2,UBR4,WARS,COPS5,ARNTL,DUSP19,FKBP5,RNF130,USP11,SMG1,KLHL24,TNIK,BCKDK,SH2D3A,CAMK1,GFM2,MRPS11,MAN1A1,PRKCH,SEC24C,FBL,RPS6KB2,KDM6B,MARCH9,GPHN,KDM5B,FGF2,SCMH1,MARS,MEN1,EIF5B,PEAK1,TARS,ALG5,AGTPBP1,CUL2,ZAK |
| 8.073e-05 | -9.42 | BHAT_ESR1_TARGETS_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_UP | 269 | 57 | 17758 | 2279 |
SRM,NCOR2,TBKBP1,THOC5,LETM1,FAM207A,C10orf2,PPARGC1B,SLC2A1,ZFP36L1,ISG20L2,TMEM104,SLC29A1,AP1B1,BHLHE40,PIP4K2A,FLNB,FLAD1,C1orf159,HR,ARMC6,LONRF2,VGF,STC2,ATRIP,MED24,GREB1,RAPGEFL1,POLR1B,TMEM120B,NUDC,MYB,ADARB1,IFRD1,CHD9,NOL6,WWC1,TBC1D16,MAT2A,POP1,CCDC3,TOE1,MYBBP1A,KDM4B,STX1A,SNX24,HSPB8,HK2,EIF2S1,SVIL,PTRH2,SCARB1,NOLC1,BRD9,PKIB,MAPT,GPATCH4 |
| 8.118e-05 | -9.42 | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | COSMIC cancer mutations | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | 678 | 121 | 17775 | 2278 |
SYT17,PRKCSH,TNFRSF21,TRPM6,SMARCA4,SBF2,PPP1R9A,LPAR3,PCDH7,CNIH3,PPFIBP1,MAD1L1,DENND1A,SPAG6,VPS13B,ZCCHC14,KMT2D,TXLNG,TFCP2,PTPRM,THSD4,ANK2,POU2F1,AKAP12,SLC35F2,MARCH6,GALK2,MEGF11,KMT2C,ZDHHC14,SON,ERC1,TPK1,ARPC3,BTBD11,DDX3X,CAMK2D,SUFU,ASTN2,ABHD3,ITGA2,CSMD3,SEMA3C,RUNX1,MAGI1,USP11,XRCC4,SPOCK3,SMG1,PARD3,USP15,HMGA2,SSH2,AUH,STX8,ANKRD17,TTC27,ARL15,NKD2,NHS,CLSTN2,RCAN1,SEMA3E,FOXP1,ENOX1,RSRC1,MBNL1,NEDD4,MTUS1,KIAA1958,PEX7,FAM50A,TSPAN2,NEBL,CFDP1,ATXN2,ANXA5,SAMD4A,C15orf41,MYB,TSHZ1,FER1L5,BDNF,TRAPPC9,ERICH1,PRIM2,WDFY3,AGPAT4,PCCA,RAPGEF4,RYR2,SCMH1,CORIN,PALLD,PLCB1,AGAP1,ZNF407,EHBP1,NAALADL2,ACOXL,PIK3CB,DNAH14,UBE2E1,DYNC1H1,LRP1B,TASP1,HELZ,BCAS3,MSH3,SLCO5A1,SLC16A1,CDKAL1,BPNT1,NCOR1,SORCS2,DDX10,SH3PXD2A,MIPOL1,ARHGAP10,COG5,HRH1 |
| 8.224e-05 | -9.41 | metal ion binding | molecular function | GO:0046872 | 4013 | 598 | 16491 | 2164 |
ADAM19,AARS2,CACNA1H,HLTF,NT5C3A,ZNF44,HMOX2,CIAPIN1,PCDH7,SKI,ZNF37A,MMP7,NEK6,ZFHX3,IKZF5,THAP4,WIZ,ZNF148,KDM5C,HRG,ZNRD1,FXN,PPM1K,LIMA1,EHMT1,MSRB3,PLEKHM3,MCM2,ZNF197,ZNF266,RBSN,SUPT4H1,RAD18,RIOK1,RUNX1,ZNF532,LPP,CARS,ADGRE2,HERC2,TNNC1,TRIP6,SIRT7,PLA2G12A,RSF1,PARN,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,EIF2S2,APLF,ALKBH8,ZNF326,CALN1,ZNF518B,PPA1,ANGPT2,ZNF675,GATAD2B,GTF2H3,TIMM8B,ZNF587,PRDM16,EPS15L1,IDH3G,TYW1,ZNF512B,RYR2,IMPDH2,MBNL2,TRIM37,ZNF655,LRP1B,NME7,PDLIM1,EHMT2,ZNF160,ADGRE5,CNOT6,BPNT1,PDLIM5,RAB11FIP4,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,AGAP6,ZMAT2,EEA1,ZBED2,PRKD3,ZSWIM7,ERI1,ZKSCAN1,MMP14,INTS12,NT5C,PEG10,ZC3H3,KMT2D,STAMBP,ZNF480,ADAM32,NUDT15,MAT2A,PDE8B,TAF2,FBXL5,ZFAND3,KDM4B,NSMCE2,PAM,FUS,BRCC3,ZBTB11,MORC2,TRIM36,ZNF786,SF3A3,JMJD6,GAS6,TRIM22,ZNF691,MBNL1,SUV39H2,TAF3,ACAP3,UNC13A,ANXA5,LTN1,PTGS1,ZNF710,FBXL19,DIS3L2,SPTAN1,DDHD1,CLYBL,POLK,ZC4H2,ZC3H18,ZNF467,PDE3B,ANXA1,RPA1,OXSR1,TOE1,ETFDH,NSD1,BAZ2B,PXDN,KDM4C,CYP24A1,TRIM16,POLR1A,RNF43,BIRC2,GIT2,FRRS1,ABL2,AMPD3,HKR1,ZNF85,ZNF3,ZMYM2,SLC25A23,DSC3,RBCK1,ZNF124,AEBP2,PPARG,BAZ2A,ZNF414,ATOX1,HSPA5,GDPD1,BRCA1,ZNF91,MLLT10,BSN,HPRT1,ZNF622,CHD3,ADAM9,PPP3CC,RNF214,C2CD5,TTN,AOC3,PRSS3,NKD2,MEX3A,SMAD7,FAN1,ZFP36L1,TRIM15,ZIC2,RLF,RNF40,RNFT2,ZNF358,TRMT13,PDE10A,LRSAM1,NT5E,CAMKK2,USP49,OBSCN,MEX3B,ZNFX1,CYB5B,NR2F1,ZNF430,DTD1,BRSK2,TESC,RNF114,MPI,CYLD,PAPD4,ARID2,LPCAT2,RPS29,ZNF83,RNF24,ZNF709,ZNF121,RPAIN,FDX1,CAD,ZNF608,ZBTB21,IDI1,JAG1,UBR1,ZDHHC6,CYB5D1,ZFP37,RNF2,PRMT3,SOBP,SEC24A,KAT8,KDM3B,PCGF3,AKAP8L,DDX41,AKAP13,CA5B,ZNF251,EXO1,SMAD3,RANBP2,ZNF333,KLF4,ITGA2,ZNF436,ZNF18,FAHD1,MUTYH,ZNF589,ZNF507,ESCO1,MCM10,MAP3K13,AGO2,ZNF346,FOXP1,POGZ,ZNF594,ADH5,NDUFV1,ANXA7,ZNF561,PRICKLE2,POLR1B,PCK2,ADAMTSL3,ZNF654,ZMYM5,TPM4,TOP3A,EXOG,RHOT2,POLR3A,ZRANB3,CDH24,DSC2,ZBTB8OS,ADAT2,FNTB,USP20,RBM26,ZNF32,NR2F2,ZNF292,MYCBP2,POLB,PRKCSH,ADAMTS6,GYG1,PRKCA,UBR5,AARS,S100A10,ZFYVE28,RNF111,ME1,CSGALNACT2,ZNF646,DPF3,NR6A1,EYA3,VSNL1,EFHC1,ZDHHC14,GNAI1,GZF1,SH3RF1,NSMCE1,ZNF81,HIC2,XPNPEP1,NRP1,CCNB1IP1,BMI1,SPOCK2,ZMAT3,SPOCK3,ZNF598,DROSHA,CELSR1,EGR1,ZHX3,TATDN3,CRACR2A,CCDC47,TGFBR2,CHD5,NDUFS7,ANXA10,PRKCE,HR,ZNF586,ASAP1,CNOT4,LPCAT1,PRPS1,SCAF11,ADARB1,SIK3,RREB1,PRIM2,PCCA,AOC2,POLA1,PLCB1,ZNF850,MTR,ARIH2,PHF6,ATP9B,ZNF425,DAGLA,CAT,MTHFD2,ALKBH3,NSF,ZZEF1,VCAN,ZBTB12,ZCCHC6,RIOK3,DPEP1,CNDP2,SMYD3,ZFHX2,ZNF254,SYT17,LIN28B,ZBTB37,UROD,OLA1,RING1,PDE3A,TRIM66,PHC2,NUBPL,ZNF827,KDM2A,TTC3,KMT2A,SAP30,ZCCHC14,MARCH6,DHX57,ZBTB25,SNCA,VDR,BAZ1A,DNAJA3,ZNF236,MBTD1,LARGE,ALKBH1,TRAF3,ANXA2,MID1,TROVE2,BRAF,B4GALT5,ZNF280C,NFX1,FARS2,SLC25A12,MYNN,LIAS,OPA1,NOL3,INPP1,RPS6KA5,ZNF239,ABL1,ZNF483,DCTPP1,PMPCA,S100A14,NT5M,MBTPS2,TSHZ1,PXN,APEX1,WDFY3,ZFYVE1,KCNMA1,APTX,KLF6,POLR2A,ZFP62,ZNF155,IREB2,ZDHHC11,HELZ,RNF138,ADK,STK4,KAT6A,ZNF76,PHF3,LETM1,KMT2E,ATRX,TRPM6,RCHY1,ZNF107,PLOD1,SIRT2,CUTC,DST,ZNF804A,LONRF2,JAZF1,ZNHIT6,ANAPC11,ZEB1,POLR3B,GALNT18,TRIM14,PRKACB,ELOF1,SRPK2,ZBTB17,TNK2,DTNB,DEAF1,TRIM13,ZNF195,ZNF680,ITPA,SIRT6,LVRN,VWCE,MINA,KSR2,HDAC8,ZSCAN2,KMT2C,CDHR3,RHOU,ZGRF1,GATA6,EME1,GALNT10,ZNF397,ZC3H8,NOCT,SEC24D,ZCCHC8,DPF2,C11orf54,TIMM10,RNF141,P3H1,ZNF354A,PRF1,ZCCHC7,ZNF629,ZNF234,HBG2,PDE4A,PPAT,ZBED4,ELP3,JMJD1C,TBXAS1,ZFP14,LIG4,PRDM1,AGAP1,SYT1,FAT1,FDPS,CDKAL1,ZFP90,PDE9A,ZBTB24,ZNF706,DLL4,ASH1L,CELSR3,ARSJ,PUDP,ZC3H13,RIOK2,ZSCAN5A,VPS18,ZNF142,ITGAX,CPSF3,ZNF460,TMLHE,MCEE,ANTXR2,COL5A2,NLN,ATP8B2,EDEM2,UBR4,S100A16,ZC3H12A,IKZF4,DUS3L,ALAD,ADNP,ZNF557,COPS5,RNF130,SMG1,YDJC,DNAJA4,DBF4,PDE4B,TKFC,CLSTN2,MAN1A1,PRKCH,GART,SEC24C,TANK,DSG2,ERI3,DMRT1,MICAL3,KDM6B,MARCH9,GPHN,KDM5B,ZNF821,KDM5A,ANKMY2,ASAP3,ZNF324B,PDE2A,ZNF407,NAPEPLD,ZNF221,RERE,ZNF708,DAGLB,ZNF330,AGTPBP1,ZRANB2,TATDN1,MMP16,ZAK,ZSWIM6 |
| 8.331e-05 | -9.39 | chondroblastoma | COSMIC cancer mutations | chondroblastoma | 560 | 103 | 17775 | 2278 |
ARHGAP26,IMMP2L,DNM3,CNTNAP3,NF1,SBF2,ENAH,RNF43,SPATS2,PTPRG,AHCYL2,PCDH7,PHC2,ZNF804A,JAG1,KDM2A,ABCA12,NUP133,ZFYVE28,RABGAP1L,SNTG2,MRPS27,FHIT,PCOLCE2,MET,LAMA4,DTNB,CHD9,GPM6A,EVL,AKAP8L,PTPRM,MED27,PREX1,ADAM32,KSR2,LAMA2,MTHFD1L,SETD7,ZDHHC14,RAB10,ZFAND3,ARMC4,ELP2,SMARCC1,TSSC1,LARGE,VPS13D,CSMD3,RUNX1,EIF2B3,BEND6,RNF214,NMD3,SMG1,TRIO,NSUN6,CLSTN2,SLC25A12,ETFB,IQGAP2,SLC39A11,TAF3,INTS7,RDX,DDX31,GMDS,LDLRAD3,FMNL2,SNX29,TOP1,HMGCR,PRIM2,CRADD,ADAMTSL3,CRIM1,ELOVL6,RDH10,MARS,ST6GALNAC3,PALLD,SYT1,PLCB1,CYB5B,AGAP1,EVI5,NAALADL2,SMPDL3B,CCDC150,CTIF,DYNC1H1,LRP1B,TASP1,ORC5,EXOC4,BCAS3,TMEM117,KIAA1328,MBD6,TBCK,MIPOL1,ARHGAP10,COG5 |
| 8.348e-05 | -9.39 | MARTENS_TRETINOIN_RESPONSE_DN | MSigDB lists | MARTENS_TRETINOIN_RESPONSE_DN | 744 | 131 | 17758 | 2279 |
SRM,PTP4A1,GNB3,ACTG1,NF1,NLE1,RPS16,ATG3,RAN,CCDC121,ZNF646,TMPO,DDN,METTL1,TRIM13,ATF4,GNL3,ARRDC3,HSPA5,TMEM216,MARCKSL1,SOX4,MGST1,CLNS1A,STOML2,DDX3X,SUPT4H1,SYNGR2,COPS6,ZNF397,ZNF598,PRPF38B,MCM6,AK2,ZIC2,C1orf52,KCNJ14,TIMM10,LYRM2,DDX56,MLX,MYC,GEMIN4,PABPC1,SERBP1,ZNF629,TIMM8B,NAA38,KIAA1143,SIGMAR1,AOC2,EIF4A2,ZNF512B,RNH1,IMPDH2,ZNF655,MGAT2,TSR1,MYBBP1A,CCDC85B,PURB,UMPS,HMBS,VMA21,CHMP2A,RSL1D1,MCM9,NOP56,FLAD1,FARSA,ACD,UCHL5,ZDHHC6,SLC38A2,NT5C,SSBP1,TLCD1,RFC4,EIF3J,NPM3,MTIF2,KIAA1586,VIM,PNN,DKC1,MAT2A,TMEM186,PUSL1,HYAL3,SMARCC1,DCXR,WDR73,H2AFX,PUS1,SEPT5,SETD6,NOLC1,MUTYH,FGFBP3,YDJC,MIF4GD,H2AFJ,LETMD1,APRT,LIAS,ZNF594,IL17RE,NOP16,TRIAP1,HIST2H3D,PNMA1,HNRNPM,RPS6KB2,TMEM126B,TMEM126A,METTL23,TBRG4,C8orf33,DDX49,TOE1,TRIB3,NME1-NME2,HNRNPH3,ADAT2,NR2F2,POLR1C,RABEP1,GPATCH4,DDIT3,SLC43A1,LRRC41 |
| 8.365e-05 | -9.39 | Post-SET_dom | interpro domains | IPR003616 | 17 | 9 | 18293 | 2341 |
NSD1,ASH1L,KMT2D,SETD1B,SUV39H2,EHMT2,SETD2,KMT2C,KMT2A |
| 8.582e-05 | -9.36 | purine-containing compound catabolic process | biological process | GO:0072523 | 49 | 17 | 16441 | 2138 |
PDE4A,ITPA,PDE4B,PDE2A,NUDT15,PDE3B,PDE3A,PDE8B,CAT,AMPD3,HPRT1,PDE10A,NT5C,OGG1,PDE9A,MUTYH,NT5E |
| 8.640e-05 | -9.36 | GSE27786_NKCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NKCELL_VS_MONO_MAC_UP | 187 | 43 | 17758 | 2279 |
SSH2,ESCO1,RWDD1,SIRT7,UROD,NDUFB5,CSNK1A1,MGA,PAIP2,NRF1,PUS3,RPS16,SACS,ARHGAP18,ATP5G2,ANKRD11,RELB,CLDND1,HTRA2,NUDC,MTHFD1,DDX24,MIOS,C2orf76,PREX1,METTL23,MAP7D1,ODC1,SON,STK10,RAB10,CLNS1A,PHF6,ATP5D,DYNC1H1,FAM135A,NME7,DUS3L,TRAP1,PUS1,CNDP2,MEF2C,RNF114 |
| 8.640e-05 | -9.36 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 187 | 43 | 17758 | 2279 |
KLHL24,COMMD10,WDR37,XPO7,UBR5,GIT2,FAM8A1,PCYOX1L,SACS,PPCDC,PTGS1,CEP63,CMPK1,POLR1E,ATP6V0D1,DENND1A,VPS13B,FAM127A,ZNF124,DDX41,NARS,PPARG,RB1CC1,USP10,SUMO3,ARID1A,MBNL2,PGD,RDH11,YIF1A,ZFAND3,HLA-DMA,ZDHHC11,LSM14A,KIAA0754,HIPK2,ORC5,GLG1,SIL1,RPS6KB1,PSAP,BRCC3,ZBTB11 |
| 8.661e-05 | -9.35 | SHH_subtype | COSMIC cancer mutations | SHH_subtype | 679 | 121 | 17775 | 2278 |
SYT17,PRKCSH,TNFRSF21,TRPM6,SMARCA4,SBF2,PPP1R9A,LPAR3,PCDH7,CNIH3,PPFIBP1,MAD1L1,DENND1A,SPAG6,VPS13B,ZCCHC14,KMT2D,TXLNG,TFCP2,PTPRM,THSD4,ANK2,POU2F1,AKAP12,SLC35F2,MARCH6,GALK2,MEGF11,KMT2C,ZDHHC14,SON,ERC1,TPK1,ARPC3,BTBD11,DDX3X,CAMK2D,SUFU,ASTN2,ABHD3,ITGA2,CSMD3,SEMA3C,RUNX1,MAGI1,USP11,XRCC4,SPOCK3,SMG1,PARD3,USP15,HMGA2,SSH2,AUH,STX8,ANKRD17,TTC27,ARL15,NKD2,NHS,CLSTN2,RCAN1,SEMA3E,FOXP1,ENOX1,RSRC1,MBNL1,NEDD4,MTUS1,KIAA1958,PEX7,FAM50A,TSPAN2,NEBL,CFDP1,ATXN2,ANXA5,SAMD4A,C15orf41,MYB,TSHZ1,FER1L5,BDNF,TRAPPC9,ERICH1,PRIM2,WDFY3,AGPAT4,PCCA,RAPGEF4,RYR2,SCMH1,CORIN,PALLD,PLCB1,AGAP1,ZNF407,EHBP1,NAALADL2,ACOXL,PIK3CB,DNAH14,UBE2E1,DYNC1H1,LRP1B,TASP1,HELZ,BCAS3,MSH3,SLCO5A1,SLC16A1,CDKAL1,BPNT1,NCOR1,SORCS2,DDX10,SH3PXD2A,MIPOL1,ARHGAP10,COG5,HRH1 |
| 8.727e-05 | -9.35 | UBE2S (ubiquitin-conjugating enzyme E2S) | protein interactions | 27338 | 54 | 19 | 16036 | 2270 |
USP7,RBCK1,CYLD,NARS,STAMBP,ATP6V1A,TANGO6,ZC3H18,USP10,BIRC2,UBC,ANAPC1,CDC16,SYNCRIP,CDK9,ANAPC11,ZNF598,ANAPC4,USP15 |
| 8.727e-05 | -9.35 | SARS (seryl-tRNA synthetase) | protein interactions | 6301 | 54 | 19 | 16036 | 2270 |
C9orf78,HARS,XPO5,ARFIP2,SIRT2,PALLD,TARS,WARS,TTC1,CAD,SNW1,DUS3L,GTF2A1,GATC,MYC,ATG7,HARS2,PFDN2,C12orf45 |
| 8.735e-05 | -9.35 | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | 294 | 61 | 17758 | 2279 |
HMGA2,TRIP6,JUP,RHOBTB1,TNFRSF21,PLA2G12A,ZNF709,QSER1,SSBP2,C11orf54,UBTD2,UBR5,POGZ,LPIN1,IQGAP2,DST,PDZD2,MCM5,DSG2,VWDE,KDELC1,MRPS27,SOCS6,RDX,SAMD13,CPSF3,CALN1,PRMT5,NRIP1,CDK6,IPO11,TMEM200A,HMGCR,MYB,MSI2,KDM5B,CRIM1,PRDM16,CDK4,TFPI,ZNF512B,PSMG1,MSRB3,HSH2D,DKC1,PLCB1,FLVCR1,CPT1A,GNAI1,PXDN,SH3RF1,ADAT2,SRD5A3,PAM,HOXA3,BIVM,CCNB1IP1,SPOCK3,CEP170,SMYD3,GCSH |
| 8.744e-05 | -9.34 | SET | smart domains | SM00317 | 47 | 17 | 9131 | 1249 |
KMT2D,ASH1L,SETD1B,KMT2E,PRDM16,EHMT1,SETD2,PRDM1,KMT2C,SETD7,NSD1,SUV39H2,EHMT2,SETD5,KMT2A,SETD6,SMYD3 |
| 8.778e-05 | -9.34 | THFDHDRGNASE | prints domains | PR00085 | 4 | 4 | 4759 | 462 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 8.795e-05 | -9.34 | MARTINEZ_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_TP53_TARGETS_DN | 560 | 103 | 17758 | 2279 |
GGT1,NDUFA5,RBFOX2,PDK4,C16orf45,SMARCA4,SSBP2,CHAC1,SAFB2,AARS,UBL5,PDE3A,MGA,LPIN1,RIOK2,IDI1,S100A10,RASSF3,PPCDC,MYH3,ZNF148,MSH4,KIAA0922,MGLL,ACSL5,SKIV2L2,UPP1,CUX1,ATF7IP2,NFIA,MARCKSL1,MCL1,NHSL1,KRTCAP2,ENC1,ZDHHC14,SON,ERC1,CLNS1A,SNCA,SLC39A14,RHOU,VDR,MSX2,RBBP8,SH3RF1,G6PD,HIPK2,INTS9,HOXA3,FKBP5,CLU,LAMA5,TNRC6A,SEPHS2,WDR75,MIF4GD,FOXO1,SUPT6H,CLK1,NKD2,GTF2IRD1,PDCD7,FOXP1,SLC39A11,HR,UBE3A,CELF1,S100A14,ERRFI1,PRMT5,LPCAT1,SCAF11,CAMKK2,AP4S1,KDM5B,MYO10,CRIM1,LSM12,TLE3,ELOVL6,XPO5,HOMER2,SCMH1,WWC1,CPT1A,PLCB1,FOXC1,NCDN,POLR3A,NR2F1,POLR2A,UBC,RDH11,PGD,EPRS,NME7,PMEPA1,FGFBP1,STX18,RIOK3,ATM,PURB |
| 8.837e-05 | -9.33 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-polycythaemia_vera | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-polycythaemia_vera | 375 | 74 | 17775 | 2278 |
SRM,CGN,ABCA3,SPATA2L,NF1,NAT10,SBF2,ARSJ,SEC16A,GIT2,GBF1,FLNB,IGSF1,AHCYL2,EDC3,PCDH7,DST,ABL2,DECR1,PDZD2,SOCS1,THAP4,SNTG2,MMP14,TTC3,SRRM2,ETV1,CHD9,NRAS,NOL8,CUX1,KSR2,AKAP13,LAMA2,LSG1,USP36,GEMIN5,CSMD3,RUNX1,BRD9,DMTF1,MUTYH,SMG1,PTPN14,NOSTRIN,BRAF,DROSHA,SUPT6H,ITFG1,ANKRD17,DYM,NFX1,FARS2,RBM20,SH2B3,PTPN2,ZNF326,UPF2,CELF1,PRPS1,HNRNPM,NAV3,FADS1,MYO10,POLK,KCNMA1,RYR2,PHF6,HELZ,TTC38,FAT1,ATM,KIF1B,SLC43A1 |
| 8.837e-05 | -9.33 | polycythaemia_vera | COSMIC cancer mutations | polycythaemia_vera | 375 | 74 | 17775 | 2278 |
SRM,CGN,ABCA3,SPATA2L,NF1,NAT10,SBF2,ARSJ,SEC16A,GIT2,GBF1,FLNB,IGSF1,AHCYL2,EDC3,PCDH7,DST,ABL2,DECR1,PDZD2,SOCS1,THAP4,SNTG2,MMP14,TTC3,SRRM2,ETV1,CHD9,NRAS,NOL8,CUX1,KSR2,AKAP13,LAMA2,LSG1,USP36,GEMIN5,CSMD3,RUNX1,BRD9,DMTF1,MUTYH,SMG1,PTPN14,NOSTRIN,BRAF,DROSHA,SUPT6H,ITFG1,ANKRD17,DYM,NFX1,FARS2,RBM20,SH2B3,PTPN2,ZNF326,UPF2,CELF1,PRPS1,HNRNPM,NAV3,FADS1,MYO10,POLK,KCNMA1,RYR2,PHF6,HELZ,TTC38,FAT1,ATM,KIF1B,SLC43A1 |
| 8.865e-05 | -9.33 | SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) | protein interactions | 6595 | 100 | 29 | 16036 | 2270 |
DPF3,TAF1,KHDRBS1,DPF2,SIRT7,SMARCD3,SMARCA4,BRCA1,ARID1A,ARID1B,POLR2A,NOP56,SMARCB1,BAZ1A,RAP1A,SMARCC1,HIF1A,CHD3,MYC,BANF1,H2AFX,NCOR1,RAN,POLR1C,PRMT5,BMI1,ZMAT3,SAP30,MYB |
| 8.870e-05 | -9.33 | histone lysine methylation | biological process | GO:0034968 | 63 | 20 | 16441 | 2138 |
KMT2D,ASH1L,SETD1B,WDR61,BAZ2A,KMT2E,SETD2,EHMT1,SETD7,KMT2C,MEN1,CHD5,DOT1L,NSD1,EHMT2,SUV39H2,CTR9,KMT2A,SETD6,SMYD3 |
| 8.875e-05 | -9.33 | HALLMARK_UV_RESPONSE_DN | MSigDB lists | HALLMARK_UV_RESPONSE_DN | 142 | 35 | 17758 | 2279 |
PHF3,MAP2K5,ID1,ATRX,SMAD7,WDR37,BHLHE40,PRKCA,TGFBR2,SCAF8,PRKCE,MYC,SYNJ2,MET,MGLL,BDNF,COL5A2,MIOS,LAMC1,PPARG,PTPRM,TFPI,KCNMA1,ATXN1,CAV1,SPOP,IRS1,SLC7A1,SMAD3,INSIG1,RUNX1,ANXA2,NRP1,PDLIM5,MMP16 |
| 8.888e-05 | -9.33 | PENG_RAPAMYCIN_RESPONSE_DN | MSigDB lists | PENG_RAPAMYCIN_RESPONSE_DN | 234 | 51 | 17758 | 2279 |
SRM,AK2,TMEM109,HSD17B10,PPP2R2A,ID2,SF3A3,RTN4,SLC29A1,MRPS11,NOP56,FARSA,IDI1,ASNS,PTRF,NOP16,PMPCA,ETF1,SSBP1,LPCAT1,TRIP13,RABEPK,PRPF19,FAM98A,GARS,SLC3A2,NARS,CDK4,NPM3,WDR18,HSPA5,WBSCR22,TCEB3,BCS1L,USP10,RNH1,MARS,PITPNB,TARS,TIMM44,SLC39A14,DDX3X,RARS,KPNA3,SYNCRIP,TRAP1,TIMM17A,EIF2S1,SQLE,TROVE2,XPO6 |
| 8.902e-05 | -9.33 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_UP | 193 | 44 | 17758 | 2279 |
SYT17,AUH,HM13,MRI1,MYO7A,PIGH,C14orf159,CD99L2,SEC16A,LCLAT1,PAG1,SLC25A20,GATC,CWC27,MAD1L1,AGL,TUBA1A,ANKMY2,RNH1,GALK2,MEF2D,EVI5,TTC28,STK10,CLNS1A,RERE,MRPL36,MLLT10,HLA-DMA,ELP2,ALAD,LUC7L3,USP20,SVIL,ATM,CRCP,CDKAL1,HEATR1,MTMR1,SYNPO,AP2S1,SRP14,ANKS1A,GPATCH4 |
| 8.902e-05 | -9.33 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 193 | 44 | 17758 | 2279 |
FEZ2,PRDX6,SUCLG1,SLC48A1,CCDC53,ITFG1,TNFRSF21,OSBPL9,ALG8,NDUFB5,HLTF,POP5,HMOX2,TGFBR2,ABHD6,REEP5,HDDC2,MAN1A1,ADH5,DUS4L,ATP5G2,MRPS27,SUCLG2,TTC3,ME1,PCK2,VCL,AGL,SLC25A1,FDFT1,MOSPD1,MTHFD1,APEX1,WDR61,ANKMY2,RNH1,RAP1GDS1,ECH1,OSBPL1A,HLA-DMA,MPV17,SNX24,BRCC3,MTMR1 |
| 8.902e-05 | -9.33 | GSE360_CTRL_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_CTRL_VS_T_GONDII_MAC_DN | 193 | 44 | 17758 | 2279 |
AK2,SULT1C2,FOXO1,KIF5A,SLC2A1,LETMD1,RCAN1,FOSL2,RPS6KA5,COX10,FLNB,FLAD1,BCAS2,KDM2A,S100A10,USPL1,FMNL1,PDE10A,KDM5C,TOMM34,LRP3,MTHFD1,ADARB1,PCGF3,ZNF124,IFNGR2,HARS,UPP1,PSMC3IP,MINA,CAMSAP2,HIST1H2BL,OASL,DKC1,ODC1,APBB3,BRCA2,HNRNPR,DPEP1,IQSEC2,KIF1B,BAG1,COG5,SLC43A1 |
| 8.902e-05 | -9.33 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP | 193 | 44 | 17758 | 2279 |
DNAJC2,AK2,DBF4,HSD17B10,TIMM10,INPP1,KDM1A,CAD,GART,ASNS,DUS4L,SUV39H2,NOP16,PPID,PPCDC,POLE3,B3GNTL1,CCDC88C,AVEN,FXN,PRPS1,TRIP13,NARS2,RFC4,PPAT,ELOVL6,MINA,SLC35F2,HIST1H4J,BRCA1,DKC1,CYB5B,EIF5B,MAK16,EXO1,SLC39A14,EPRS,SRRD,TBPL1,SLC16A1,HEATR1,RWDD2B,EIF2B3,DDX10 |
| 9.080e-05 | -9.31 | - | gene3d domains | 3.40.50.620 | 42 | 16 | 9988 | 1398 |
CARS,WARS2,LARS2,RARS2,MARS,VARS,YARS2,ETFB,WARS,FLAD1,EPRS,RARS,ASNS,TRMU,DPH6,YARS |
| 9.168e-05 | -9.30 | ribonucleotide catabolic process | biological process | GO:0009261 | 28 | 12 | 16441 | 2138 |
HPRT1,AMPD3,PDE4A,ITPA,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,NT5E,PDE8B |
| 9.264e-05 | -9.29 | SNF2_N | pfam domains | PF00176 | 32 | 13 | 16629 | 2165 |
CHD7,CHD9,SRCAP,EP400,ATRX,CHD3,SMARCAD1,SMARCA4,CHD2,HLTF,CHD5,RAD54B,ZRANB3 |
| 9.333e-05 | -9.28 | RNA polymerase core enzyme binding | molecular function | GO:0043175 | 24 | 11 | 16491 | 2164 |
PAF1,ELP2,ELP3,AGO2,WAC,ZNF326,CTR9,IKBKAP,SCAF8,SMYD3,CDC73 |
| 9.495e-05 | -9.26 | regulation of cardiac muscle cell action potential | biological process | GO:0098901 | 17 | 9 | 16441 | 2138 |
CAMK2D,DSC2,JUP,ANK2,DSG2,RYR2,CAV1,DSP,NOS1AP |
| 9.641e-05 | -9.25 | microtubule cytoskeleton | cellular component | GO:0015630 | 1041 | 173 | 17570 | 2233 |
PTP4A1,MYCBP2,POLB,CUL7,KIF5A,MKS1,TUBE1,CSPP1,SIRT2,BIRC2,SKI,DST,SRPRB,NEK6,RASSF3,XRCC2,MAD1L1,RELB,SUCLG2,FNIP2,RAN,CEP135,CDK6,SPAG6,PRKACB,CEP128,ATF4,KATNAL1,EYA3,KIF15,CAMSAP2,EFHC1,BRCA1,MCM2,CCDC28B,KIF16B,GNAI1,DDAH2,BRCA2,RAD18,CHD3,CCDC146,PQBP1,DNAH2,TSEN2,C2CD5,HERC2,DCTN3,IFT57,CDC42EP2,PAX2,DPF2,SMAD7,DNAH1,MTUS1,CEP164,NAV1,CEP290,ALKBH8,TIMELESS,CCDC124,ATP6V0D1,AKAP11,PEA15,IFT43,HAUS6,RAP1GAP2,KIAA0586,ATAT1,PSMA1,MAP7D1,EVI5,SRA1,DNAH14,IRS1,DYNC1H1,ATXN7,SPAG9,BICD1,NME7,SDCCAG8,DNAH17,CCDC85B,SLC16A1,TBL1X,NCOR1,BRSK2,PRKAR2A,RTTN,DNM3,ID1,CYLD,MAP2K5,RAB11FIP4,PCNT,BIRC6,PAFAH1B1,C16orf45,OLA1,MYH9,TBCCD1,TUBB6,RADIL,PIBF1,HSPA1A,RPGRIP1L,SBDS,BLOC1S2,RMDN3,CEP63,PXK,LYST,PRPF19,TUBA1A,ARHGEF10,TTC28,UBR4,SERP1,IFT81,CDC16,IKZF4,DCXR,G6PD,WDR73,IFT140,XRCC4,YEATS2,MID1,CEP170,PARD3,MAPT,KIZ,KLC4,PDE4B,MAP1S,KIF5C,ID2,CEP126,CSNK1A1,MBNL1,MAD2L2,SFI1,IQGAP2,TADA3,TTLL11,DCTN4,SHMT2,S100A14,DYNC2H1,FBXO31,NUDC,SPTAN1,PXN,CEP83,TTLL5,VPS37A,APEX1,CEP295,CCDC113,RANGAP1,PTK2,HSPA1B,MFN2,YIF1A,KLHL22,WDR35,BCAS3,FNTB,SVIL,ATM,USP20,IGBP1,KIF1B |
| 9.653e-05 | -9.25 | CTGCAGY_UNKNOWN | MSigDB lists | CTGCAGY_UNKNOWN | 713 | 126 | 17758 | 2279 |
PTP4A1,SLC48A1,PAFAH1B1,RBFOX2,PPARGC1B,HFM1,TNXB,CD99L2,CSNK2A1,FAM122B,BCOR,TMEM132A,UBR5,SEMA6A,GIT2,IGSF1,PLXNB1,WNT2B,PCDH7,NDUFB3,NBEA,SHF,KIAA0922,ETV1,ZMYM2,CDK6,CASP10,SOBP,KDM3B,GPM6A,GARS,NRAS,ATF4,TUBA1A,ENHO,ARRDC3,LGALS1,VSNL1,LRRC8A,COTL1,CCNDBP1,KCNH2,SOX4,FGFR1,ZBTB25,GNAI1,MLLT10,PAF1,CAMK2D,GATA6,ADNP,METTL6,POLR3E,HOXA3,SPOCK2,DMTF1,ZNF532,ZMAT3,PTPN14,RAB30,MAPT,USP15,RELL2,SARS,MINK1,EGR1,PID1,RTN4,ZFP36L1,ATF7IP,BTBD9,IP6K2,BHLHE40,FOXP1,FOXO3,POGZ,PIP4K2A,NEDD4,MTUS1,CEP164,MLX,MCAM,CACNB2,DCTN4,RAPGEFL1,NLGN3,CELF1,CALN1,ANGPT2,BDNF,FGF9,STAG1,GPHN,CRIM1,FOXN3,PPP1R21,JMJD1C,EIF4A2,RYR2,SMARCD3,MEX3B,RABAC1,FAM126B,PTK2,AGAP1,MBNL2,PHF6,NCDN,NR2F1,IRS1,CDH24,NSD1,ETFDH,LRP1B,SPAG9,GTF2A1,RPL28,CDK9,HERC1,CCDC85B,TBPL1,SLCO5A1,USP20,GGT7,C18orf25,STK4 |
| 9.834e-05 | -9.23 | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_UP | 188 | 43 | 17758 | 2279 |
C9orf78,PCNT,SCAMP3,SUCLG1,HSD17B10,PIGH,SF3A3,PRKCA,HDDC2,CIAPIN1,MPHOSPH10,UBE3A,ZNHIT6,BANF1,SUCLG2,YARS,AVEN,PRF1,PNMA1,TERF2,ACSL5,RANBP6,EVL,SKIV2L2,TSPYL4,ELP3,WBSCR22,PSMA1,SUMO3,DDX60,MTR,TARS,CLNS1A,RPA1,YIF1A,MGAT2,PWP1,EPRS,FBXO21,MPV17,PTPN4,ZNF32,LRRC41 |
| 9.834e-05 | -9.23 | GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP | MSigDB lists | GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP | 188 | 43 | 17758 | 2279 |
CARS,KIAA0232,SLC25A44,LYRM2,NDUFB3,SLC25A20,PRKCH,CD96,NPRL2,UCHL5,RDX,SNAPC5,HTRA2,PMS1,NAA38,PCCA,ANKMY2,ABCF2,APTX,DKC1,UBE2K,EHBP1,ABCF1,C1orf174,TMEM186,TPK1,SPOP,GLS,MGAT2,SLC39A14,RARS,TMCO1,ALG5,WDR5B,NME7,FAM114A2,TNFRSF1A,WDR7,RAD51B,GPN1,PEX13,USP11,TPM1 |
| 9.834e-05 | -9.23 | GSE27786_LSK_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_LSK_VS_CD4_TCELL_UP | 188 | 43 | 17758 | 2279 |
IMMP2L,PIGN,PGPEP1,LPCAT2,FANCD2,PPHLN1,GTF2IRD1,TUBB6,C11orf54,STAM,MPHOSPH10,SUV39H2,ZSWIM7,DHX33,NUP133,DTNBP1,C16orf58,DYNC2H1,POLR1E,PRMT3,HTRA2,NARS2,FADS1,TFCP2,ZC4H2,PSPC1,PACRGL,CLNS1A,YTHDF2,ZRANB3,SLC7A1,KLHL22,RETSAT,MSRA,FAM135A,KIAA0355,PEMT,FDPS,ALKBH1,ZNF32,NR2F2,PDSS2,CTXN1 |
| 9.846e-05 | -9.23 | MRNA_METABOLIC_PROCESS | MSigDB lists | MRNA_METABOLIC_PROCESS | 84 | 24 | 17758 | 2279 |
SCAF11,AUH,PRPF31,RNMT,SFSWAP,KHDRBS1,TRA2A,SF3A3,SMG7,HSPA1A,HSPA1B,SPOP,GEMIN5,SNW1,SRSF2,PHF5A,HNRNPR,UPF2,CELF1,CPSF3,PABPC1,SMG1,SF3A1,SRPK2 |
| 1.001e-04 | -9.21 | BILD_HRAS_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_HRAS_ONCOGENIC_SIGNATURE | 241 | 52 | 17758 | 2279 |
CDCP1,CHST11,FN1,EGR1,ITPRIP,FAM46B,TRIM22,TGFB2,INPP1,PHLDA2,FLNB,NAMPT,MTUS1,ZNF827,ZBED2,ZNF608,SOCS1,MMP14,GLTP,MFAP2,SRRM2,NT5E,TOP1,NAV3,ARNTL2,KDM6B,MALL,SESN2,UPP1,AKAP12,MCL1,MAP7D1,MBNL2,DLST,ODC1,KLF6,ANGPTL4,TCF7L2,OXSR1,C6orf141,STX1A,FGFBP1,ITGA2,TBX3,HK2,AHNAK2,RUNX1,TPM1,NOLC1,MID1,ARHGAP27,TNRC6A |
| 1.010e-04 | -9.20 | MODULE_15 | MSigDB lists | MODULE_15 | 351 | 70 | 17758 | 2279 |
TCF12,PTP4A1,ADAM19,SLC2A1,CSNK2A1,GYG1,HMOX2,BIRC2,RAC3,MAP2K3,LPIN1,CAD,SRSF2,RAP1A,PMAIP1,WIZ,CORO1A,KDM5C,CDK6,HTRA2,PRKACB,PRPF19,SF3A1,BRD4,ITPA,PARP2,PITPNB,SOX4,MCM2,PLIN2,DDX3X,HTR7,HLA-DMA,HPRT1,INSIG1,COPS5,ARL6IP5,FKBP5,MAGI1,BMI1,NOLC1,TROVE2,MCM6,AK2,UBXN1,HSD17B10,APRT,ZIC2,MBNL1,IQGAP2,DDIT4,SLC7A11,MYC,SHMT2,CD44,NRIP1,SERBP1,MYB,FDFT1,FADS1,APEX1,TBXAS1,ADSL,PTPN12,ANXA1,RPA1,GADD45A,SYNCRIP,DDIT3,SLC43A1 |
| 1.011e-04 | -9.20 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 194 | 44 | 17758 | 2279 |
CARS,SLC2A1,OLA1,JMJD6,CHCHD10,BHLHE40,RNASEH2B,DDIT4,DECR1,NDUFV1,IDI1,NVL,MCM5,PDS5B,ALDH18A1,CARM1,FDFT1,SAP30,RFC4,PRIM2,PSAT1,SKAP2,MINA,RNH1,BRCA1,MCM2,CYB5B,TRIM37,TAMM41,TPD52L2,TRIB3,MTHFD2,HSDL2,SYNGR2,FDPS,HK2,XPNPEP1,CRCP,ANXA2,HMBS,RBPJ,NDUFS5,DHCR7,BLMH |
| 1.011e-04 | -9.20 | GSE17721_LPS_VS_PAM3CSK4_6H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_6H_BMDM_DN | 194 | 44 | 17758 | 2279 |
BCCIP,DYM,PSTPIP2,WDR13,PIGH,ZFP36L1,RCAN1,MAP2K3,LPIN1,PRKCH,FLAD1,POLR3D,RRN3,HVCN1,ASNS,BCAS2,MYC,ZNF326,GTF2H1,AHCYL1,PRMT3,TMEM14C,HSD17B12,GARS,RDH10,IMPDH2,FAM126B,EVI5,C19orf70,MGST1,CLNS1A,POLR2A,MLLT10,MFN2,SEC31A,COPS5,COQ9,MBTD1,MPV17,SLC25A19,ZC3H8,FAM118A,NIT1,GALE |
| 1.027e-04 | -9.18 | regulation of translation | biological process | GO:0006417 | 292 | 61 | 16441 | 2138 |
ZNF706,MIF4GD,EIF3C,LARS2,KHDRBS1,AGO2,ZFP36L1,VARS,IGF2BP2,GIGYF2,FOXO3,AARS,PAIP2,IGF2BP3,GATC,ATXN2,SELT,ETF1,CELF1,IGF2BP1,YBX3,LARP4B,SAMD4A,PABPC1,RPS6KB2,ATF4,EIF4E3,EIF3J,MTIF2,CDK4,EIF4A2,EIF2A,SOX4,ENC1,EIF5B,GUF1,ABCF1,SERP1,PUM3,EIF3H,CTIF,DDX3X,EPRS,IREB2,EIF4ENIF1,SYNCRIP,DNAJC1,TRAP1,LSM14A,PER1,EEFSEC,EIF2S1,DTD1,RPS6KB1,NCBP2,CNOT6,EIF2B3,UQCC2,UQCC1,AGO3,TNRC6A |
| 1.043e-04 | -9.17 | FTSJ3 (FtsJ homolog 3 (E. coli)) | protein interactions | 117246 | 96 | 28 | 16036 | 2270 |
NIFK,DDX24,UTP14A,GNL3,SIRT7,NFIA,CSNK2A1,DKC1,RBM19,EIF5B,NOP58,MAK16,PUM3,NOP56,PES1,PWP1,TSR1,DDX56,ZNF622,MPHOSPH10,MYBBP1A,SURF2,SRP68,COPS5,SET,RNF2,FBL,ZC3H3 |
| 1.050e-04 | -9.16 | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 41 | 17758 | 2279 |
ZNF292,ASCC1,CHMP2A,FEM1C,SUPT6H,CLK1,RBFOX2,ACTR3,MYNN,ISG20L2,CCDC47,BHLHE40,DNAJC22,RLF,DDIT4,KCTD11,NOVA2,CYB5D1,FUT11,LONP1,LRRC20,SEC24A,FAM127A,PDK1,DDX41,RNMT,TRA2A,ZNF654,LDHA,ARHGEF12,ONECUT2,ARL5B,TAF9B,PLIN2,PAF1,OXSR1,DDX50,UBAP1,PER1,HK2,CSRNP1 |
| 1.056e-04 | -9.16 | embryo development ending in birth or egg hatching | biological process | GO:0009792 | 601 | 110 | 16441 | 2138 |
CUL4A,PCNT,LUZP1,BIRC6,WDR74,NF1,MKS1,MYH9,PBX1,ENAH,NLE1,SLC39A1,KDM1A,RPGRIP1L,AMBRA1,SBDS,SMARCB1,SKI,CHD7,RRN3,DNAJB6,XRCC2,ANKRD11,MMP14,ZEB1,HYAL1,FXN,PRKACB,PRPF19,DSC3,DEAF1,KMT2D,BRD4,GRHL3,COL4A3BP,SATB2,BRCA1,PITPNB,MTHFD1L,SOX4,SLC35D1,TCTN1,POLG2,FLVCR1,FGFR1,SMAD3,SKIL,EPN2,RBBP8,BRCA2,GATA6,MKL2,ARL13B,MBTD1,RAD51B,HOXA3,IFT140,SEMA3C,DLX2,RUNX1,CCNB1IP1,MEF2C,IFT57,CHST11,CELSR1,SEC24D,PAX2,MAPK8IP3,ZFP36L1,ZIC2,LIAS,RNASEH2B,PHGDH,TGFBR2,MBNL1,ELL,ZNF358,EIF2S2,COPS3,CTR9,YBX3,AMOT,SOX6,TERF2,MTHFD1,MYB,FGF9,MSX1,FZD3,SETD2,RDH10,LIG4,PRDM1,ARID1A,FOXC1,TCF7L2,RPA1,DKK1,MFN2,KIDINS220,PALB2,HIF1A,TBX3,ATM,RBPJ,APAF1,BMP4,NR2F2,MMP16,STK4 |
| 1.058e-04 | -9.15 | XRCC1 (X-ray repair complementing defective repair in Chinese hamster cells 1) | protein interactions | 7515 | 42 | 16 | 16036 | 2270 |
POLB,CUL7,APEX1,POLK,PARP2,CSNK2A1,BRCA1,APTX,S100A16,RPA1,APLF,ARL6IP5,UBAP2L,TIMELESS,RAN,OGG1 |
| 1.063e-04 | -9.15 | LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS | MSigDB lists | LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS | 14 | 8 | 17758 | 2279 |
FARSA,SARS,GARS,NARS,FARS2,VARS,MARS,YARS |
| 1.063e-04 | -9.15 | regulation of ventricular cardiac muscle cell action potential | biological process | GO:0098911 | 8 | 6 | 16441 | 2138 |
RYR2,CAV1,DSC2,JUP,DSP,DSG2 |
| 1.066e-04 | -9.15 | nuclear chromosome | cellular component | GO:0000228 | 483 | 90 | 17570 | 2233 |
TCF12,ATRX,PLRG1,NAT10,CSNK2A1,SMARCA4,SIRT2,TNKS1BP1,RING1,KDM1A,SMARCB1,TERF2IP,SLX4,BCAS2,KDM2A,ACD,UCHL5,RNF2,POLE3,MSH4,SPIDR,CTC1,PRPF19,HMBOX1,BRD4,SIRT6,NOL6,HDAC8,BRCA1,HIST1H2BL,MCM2,ENC1,CHAF1A,BAZ1A,SMAD3,TRRAP,SMARCC1,TP53BP1,KLF4,E2F4,H2AFX,PUS1,NFRKB,EME1,CCNB1IP1,HMGA2,EP400,NIFK,TTN,MCM6,MCM10,TCF3,DPF2,SIRT7,H2AFJ,MLH1,CDC73,HIST2H2AB,POGZ,SFR1,POLR3D,MCM5,MBD2,BUD31,TIMELESS,NRIP1,TERF2,TOP1,GATAD2B,TRNP1,SMARCAD1,POLA1,SMARCD3,APTX,HIST1H4J,ARID1A,PLCB1,FOXC1,TCF7L2,ZRANB3,RPA1,POLR3G,POLE2,EHMT2,ORC5,MSH3,PURB,NCOR1,KDM4C,IPO4 |
| 1.085e-04 | -9.13 | SET | prosite domains | PS50280 | 51 | 17 | 11866 | 1504 |
ASH1L,KMT2D,SETD1B,KMT2E,PRDM16,SETD2,EHMT1,PRDM1,KMT2C,SETD7,NSD1,EHMT2,SUV39H2,SETD5,KMT2A,SETD6,SMYD3 |
| 1.092e-04 | -9.12 | negative regulation of macromolecule biosynthetic process | biological process | GO:0010558 | 1398 | 228 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,ATF4,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,BRCA2,SUPT4H1,EIF4ENIF1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,TNRC6A,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,PID1,BARX2,ZIC2,RSF1,CDC73,ABCA7,IGF2BP3,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,IGF2BP1,PRMT5,NRIP1,TERF2,MYB,ZNF675,GATAD2B,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,EPRS,MYBBP1A,SYNCRIP,EHMT2,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,AGO3,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,MAP2K5,CYLD,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,PAIP2,ZBTB21,ACD,PPID,DNAJB6,RNF2,CTC1,CASP8AP2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,ENC1,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,EIF2B3,SETD6,YEATS2,HMGA2,DNAJC2,NOSTRIN,NCOR2,TCF3,AGO2,H2AFJ,NFX1,ID2,IGF2BP2,ATF7IP,GAS6,TRIM22,BHLHE40,RPS6KA5,FOXP1,GIGYF2,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,CELF1,YBX3,ERRFI1,SAMD4A,DMRT1,SOX6,FGF9,MSX1,APEX1,KDM5B,PSPC1,FOXN3,SCMH1,HIST1H4J,IL6R,PDE2A,MEN1,UBC,ZRANB3,RERE,MKX,DKK1,TRIB3,NSD1,IREB2,TBX3,SET,EIF2S1,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 1.093e-04 | -9.12 | chordate embryonic development | biological process | GO:0043009 | 595 | 109 | 16441 | 2138 |
CUL4A,PCNT,LUZP1,BIRC6,WDR74,NF1,MKS1,MYH9,PBX1,ENAH,NLE1,SLC39A1,KDM1A,RPGRIP1L,AMBRA1,SBDS,SMARCB1,SKI,CHD7,RRN3,DNAJB6,XRCC2,ANKRD11,MMP14,ZEB1,HYAL1,PRKACB,PRPF19,DSC3,DEAF1,KMT2D,BRD4,GRHL3,COL4A3BP,SATB2,BRCA1,PITPNB,MTHFD1L,SOX4,SLC35D1,TCTN1,POLG2,FLVCR1,FGFR1,SMAD3,SKIL,EPN2,RBBP8,BRCA2,GATA6,MKL2,ARL13B,MBTD1,RAD51B,HOXA3,IFT140,SEMA3C,DLX2,RUNX1,CCNB1IP1,MEF2C,IFT57,CHST11,CELSR1,SEC24D,PAX2,MAPK8IP3,ZFP36L1,ZIC2,LIAS,RNASEH2B,PHGDH,TGFBR2,MBNL1,ELL,ZNF358,EIF2S2,COPS3,CTR9,YBX3,AMOT,SOX6,TERF2,MTHFD1,MYB,FGF9,MSX1,FZD3,SETD2,RDH10,LIG4,PRDM1,ARID1A,FOXC1,TCF7L2,RPA1,DKK1,MFN2,KIDINS220,PALB2,HIF1A,TBX3,ATM,RBPJ,APAF1,BMP4,NR2F2,MMP16,STK4 |
| 1.099e-04 | -9.12 | ACACTGG,MIR-199A,MIR-199B | MSigDB lists | ACACTGG,MIR-199A,MIR-199B | 149 | 36 | 17758 | 2279 |
CELSR1,NPAS2,ST6GAL1,MYH9,ZNF44,CDC73,SACS,IKBKB,CLK2,PXN,GCNT2,LAMC1,ADAMTSL3,ANK2,HSPA5,ZNF512B,CAV1,ARID1A,EIF5B,RAB10,ARIH2,TAF9B,DDX3X,ARHGAP21,ATXN7,RANBP2,KIAA0355,HIF1A,UBAP1,HIPK2,LARGE,ARHGAP12,SH3PXD2A,TSPAN5,KIF1B,STK4 |
| 1.100e-04 | -9.12 | KAUFFMANN_DNA_REPAIR_GENES | MSigDB lists | KAUFFMANN_DNA_REPAIR_GENES | 224 | 49 | 17758 | 2279 |
POLB,XPC,ATRX,FANCD2,MLH1,MAD2L2,ABL1,MBD2,XRCC2,MAD1L1,GTF2H1,POLE3,MSH4,N4BP2,OGG1,TERF2,TOP1,RFC4,PMS1,GTF2H3,RFC3,APEX1,POLK,POLA1,TOP3A,LIG4,APTX,BRCA1,POLG2,RAD54B,CHAF1A,RPA1,EXO1,BRCA2,RBBP8,ALKBH3,RAD18,GADD45A,POLE2,TP53BP1,H2AFX,MSH3,RAD51B,ALKBH1,ATM,EME1,WDR33,XRCC4,MUTYH |
| 1.108e-04 | -9.11 | liver | COSMIC cancer mutations | liver | 16979 | 2209 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,LSM14A,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,SFR1,ABL1,ATXN7L1,NEBL,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,TMEM126B,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,DMXL2,TCF12,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,FIP1L1,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,LPCAT3,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,UBAP2,MYBBP1A,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,PDLIM1,GSTO2,FGFBP1,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,NR2C2AP,CHMP2A,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,IGF2BP2,ATF7IP,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,METTL23,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,C16orf52,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.118e-04 | -9.10 | KIM_MYC_AMPLIFICATION_TARGETS_UP | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_UP | 189 | 43 | 17758 | 2279 |
MYCBP2,PRDX6,SUCLG1,LRRC28,XPC,DDX18,NDUFAF2,SEMA6A,NOP56,CHN1,SACS,EIF2S2,DHX33,PHKA1,MYC,PCOLCE2,SSBP1,FBL,AGL,PRPS1,HSD17B12,RABEPK,ADARB1,KCNQ3,PPAT,EIF3J,C1QTNF1,MINA,PSMG1,GALK2,AKAP13,DKC1,ODC1,MAK16,MRPL36,HPRT1,ARL6IP5,PEMT,SLC16A1,CDKAL1,ABCC3,MAGI1,BLMH |
| 1.118e-04 | -9.10 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN | 189 | 43 | 17758 | 2279 |
PIGM,C17orf80,URB2,B4GALT5,HSD17B10,TBCCD1,PPIL1,ISG20L2,SLC29A1,NLE1,UBL5,YARS2,FLAD1,PUS3,ARHGAP18,ARMC6,PRADC1,NT5E,MYB,RFC4,WDR36,ZNF234,CRIM1,TMEM126B,SCFD2,UTP15,PSMG1,PTK2,PITPNB,PEAK1,RBM28,C19orf70,CHCHD6,PGD,SLC7A1,CDC16,POLE2,TRAP1,TP53BP1,FAM114A2,ACOX1,ZNF557,DDX10 |
| 1.138e-04 | -9.08 | ZHAN_MULTIPLE_MYELOMA_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD2_DN | 46 | 16 | 17758 | 2279 |
PAQR6,LDHA,NFIA,MSRB3,BZW2,NEDD4,MRPS30,POLR3G,GART,HK2,PRICKLE2,ANXA2,MB21D2,AVEN,PPA1,HN1 |
| 1.146e-04 | -9.07 | GSE27786_BCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_BCELL_VS_NEUTROPHIL_UP | 195 | 44 | 17758 | 2279 |
SARS,PPARGC1B,SLC29A1,MLH1,NUP43,COX10,TIMM10,MBNL1,UBE3A,DHX33,IKBKB,ANAPC10,RELB,RNF2,NOC3L,ALDH18A1,SF3A1,RBCK1,FAM172A,PDK1,DDX24,PARP2,ZC4H2,CDK4,PCCA,NOL8,SETD2,RSBN1,POLR2A,ZNF655,ZBTB25,POP1,ZNF266,TASP1,POLE2,CC2D1B,LUC7L3,ARNTL,MSH3,ALKBH1,PUS1,EIF2B3,RABEP1,GCSH |
| 1.146e-04 | -9.07 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 195 | 44 | 17758 | 2279 |
SRM,CARS,POLR1A,OLA1,TMEM109,JMJD6,CHCHD10,RNASEH2B,DCTPP1,CAD,POLR3D,IDI1,NVL,MCM5,PDS5B,ALDH18A1,PPA1,TRIP13,CARM1,ELOF1,METTL1,RFC4,PRIM2,MINA,MRPS10,RNH1,BRCA1,MCM2,CYB5B,TRIM37,BATF3,TAMM41,TPD52L2,MTHFD2,SYNGR2,HK2,CRCP,NCBP2,NDUFS5,RBPJ,HMBS,DHCR7,BLMH,GCSH |
| 1.146e-04 | -9.07 | GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDM_DN | 195 | 44 | 17758 | 2279 |
PTCD2,FN1,ZCCHC8,SIRT7,DBF4,PIGH,GRINA,RBM19,NUP160,RHBDD1,POM121,RRN3,RAP1A,SACS,UBE3A,INTS7,PYCRL,RNF111,GLTP,PTGS1,ALDH18A1,TMEM120B,TMEM14C,CLK2,NIPSNAP1,FAM120B,LRRC20,DEAF1,GMFB,TRIM37,EVI5,POLR3A,POLR3G,MGAT2,HELZ,UBAP1,ARNTL,DNAJC12,CRCP,SLC25A11,WDR33,ECHDC1,RNF214,KIF1B |
| 1.146e-04 | -9.07 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 309 | 63 | 17758 | 2279 |
KLHL24,NCOR2,MAP2K5,FN1,FOXO1,RHOBTB1,TRAK1,PID1,IGF2BP2,TGFB2,TGFBR2,SNAPC4,PPP1R9A,MFSD10,FLNB,CEP164,ZNF804A,DST,ZNF827,S100A10,TBC1D22A,SLC35C2,VCL,SRRM2,FMNL2,NT5E,SPTAN1,LAMA4,TSHZ1,SLC40A1,IL11RA,COL5A2,LAMC1,LIMA1,ZFYVE1,TSPYL4,FOXN3,ARID5B,TFPI,NFIA,VIM,MEF2D,SOX4,GPNMB,EDEM2,FOXC1,CRYBG3,ISG15,NEU1,TCF7L2,DKK1,GNAI1,CAMK2D,YIPF2,ELP2,MSH3,ZNF436,CSRNP1,DISP1,DLX2,PSAP,MB21D2,MEF2C |
| 1.157e-04 | -9.06 | skin-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-squamous_cell_carcinoma | 506 | 94 | 17775 | 2278 |
ARHGAP26,CYLD,ARID2,NF1,ATRX,FANCD2,VTI1A,DDR2,SMARCA4,MYH9,RIPK1,FLNB,SBDS,SMARCB1,ABL2,ZBED2,SOCS1,MMP14,FHIT,KDM5C,MET,KMT2A,ETV1,ZMYM2,KIAA1549,CDK12,MAML3,DBN1,PMS1,NRAS,KMT2D,ABCC4,PPARG,ITPA,CDK4,ATXN1,MCL1,ABCC2,BRCA1,KMT2C,ERC1,FGFR1,DOT1L,SMAD3,RANBP2,BRCA2,GATA6,PER1,RUNX1,MAGI1,LAMA5,MUTYH,CARS,EP400,BRAF,XPC,MYNN,ZIC2,ZFP36L1,TGFBR2,CDC73,FOXO3,SH2B3,ABL1,ANXA7,MYC,ATIC,FBXO31,PRF1,SNAPC5,SPTAN1,TOP1,ADAMTSL3,ARID5B,SETD2,ZBED4,TPM4,ARID1A,PRDM1,TCF7L2,SEC31A,NSD1,LRP1B,PALB2,ARID3B,HIF1A,MED15,BIVM,ATM,SIL1,UMPS,RABEP1,C7orf26,DDIT3 |
| 1.157e-04 | -9.06 | CTACTGT,MIR-199A | MSigDB lists | CTACTGT,MIR-199A | 172 | 40 | 17758 | 2279 |
ZNF706,FN1,ACTG1,FOXP1,MBNL1,GIGYF2,CHD7,RNF141,SUB1,SIPA1L3,PDS5B,RNF111,ZEB1,MET,ETV1,TOP1,SOBP,GPM6A,AEBP2,RREB1,ADAMTSL3,ANK2,ZNF654,ARRDC3,SUMO3,MEF2D,PHF6,DCBLD2,ARHGAP21,BAZ2B,VCAN,LUC7L3,DPP4,SLCO5A1,MBD6,RUNX1,USP11,FNBP1L,BRSK2,TSPAN5 |
| 1.170e-04 | -9.05 | TTTGCAC,MIR-19A,MIR-19B | MSigDB lists | TTTGCAC,MIR-19A,MIR-19B | 499 | 93 | 17758 | 2279 |
PTP4A1,CGN,SNX27,CYLD,FEM1C,PAPD4,SLC48A1,NPAS2,ATRX,SBF2,PTPRG,SLC6A8,LCLAT1,RTN1,RAP1A,KDM2A,SOCS1,NBEA,RNF111,RNF2,ZNF3,ETV1,DENND1A,TBC1D8,FLNC,DBN1,GPCPD1,ARRDC3,ATXN1,MEF2D,SOX4,ST3GAL5,BSN,DCBLD2,YTHDF2,DDX3X,ARHGAP21,EPN2,RBBP8,KPNA3,ADNP,PRRT3,ARC,CEP170,TNRC6A,LPP,CADM4,EFNB2,MINK1,FAM46B,B4GALT5,RFX1,C16orf52,NHS,MED13L,WDR26,MON2,TGFBR2,FOXP1,MBNL1,SPIRE1,ANXA7,PRICKLE2,RAPGEFL1,ARHGAP1,MAP3K14,MAP3K12,CNOT4,SOX6,PKNOX1,NAV3,VPS37A,WDFY3,LSM12,RAPGEF4,RAP1B,ARHGEF12,ARRDC4,SYT1,MBNL2,PLCB1,ARIH2,NME7,PMEPA1,L3MBTL3,SPEN,VPS37B,TAF4,ARHGAP12,CNOT6,PSAP,MBD6,MB21D2 |
| 1.170e-04 | -9.05 | chr12q24 | MSigDB lists | chr12q24 | 201 | 45 | 17758 | 2279 |
NCOR2,EP400,SDSL,MVK,ZCCHC8,MED13L,POP5,RBM19,GIT2,DENR,SH2B3,RNFT2,ANKRD13A,HVCN1,GATC,DHX37,TRIAP1,C12orf76,GLTP,POLR3B,RAN,TMEM120B,ACADS,GTF2H3,PXN,CAMKK2,SETD1B,SFSWAP,KSR2,OASL,TCTN1,UBC,ARPC3,BTBD11,TMEM132B,FBXO21,IFT81,TBX3,VPS37B,HSPB8,SCARB1,PUS1,PGAM5,WDR66,TESC |
| 1.176e-04 | -9.05 | NPM1 (nucleophosmin (nucleolar phosphoprotein B23, numatrin)) | protein interactions | 4869 | 454 | 93 | 16036 | 2270 |
CUL7,CUL4A,PRDX6,MRPL10,RSL1D1,CSNK2A1,SMARCA4,PRKCA,URB1,PELP1,FLNB,NOP56,MRPS30,SHC1,S100A10,NVL,PPID,FMNL1,GLYR1,PAK1IP1,CPSF3,FTSJ3,CDC37,FLNC,GLTSCR2,SIRT6,NPM3,HSPA5,LGALS1,BRCA1,RBM28,MAK16,PUM3,USP36,EIF3H,GZF1,DOT1L,OSBPL1A,DDX3X,TRRAP,HNRNPR,COPS5,CEBPZ,H2AFX,FUS,ANXA2,COPS6,MID1,PTPN14,USP15,BANP,HMGA2,NIFK,FN1,TTC27,SIRT7,WDR26,DDX56,CTNNBL1,PTRF,NOP16,TAF3,MYC,DDX31,NOC3L,YBX3,PPA1,AKAP11,HNRNPM,TOP1,RPS6KB2,NIPSNAP1,RANBP6,APEX1,DDX24,UTP15,RNH1,IMPDH2,CHCHD6,PHF6,UBC,RPA1,POP1,ZFP62,PWP1,IRS1,KPNA1,MYBBP1A,GADD45A,CUL2,EIF2S1,SENP3,GPATCH4 |
| 1.177e-04 | -9.05 | BRIX1 (BRX1, biogenesis of ribosomes) | protein interactions | 55299 | 73 | 23 | 16036 | 2270 |
ADARB1,NIFK,CUL7,DDX24,DDX18,SIRT7,UTP15,ZNF346,MAK16,PABPC4,PUM3,NOP56,PES1,DDX56,ZNF622,SURF2,NOC3L,MDN1,FBL,NOLC1,ZC3H3,PABPC1,FTSJ3 |
| 1.177e-04 | -9.05 | nuclear ubiquitin ligase complex | cellular component | GO:0000152 | 42 | 15 | 17570 | 2233 |
PHC2,ANAPC1,CUL7,CDC16,BRE,ANAPC13,ANAPC11,ANAPC10,RNF2,BRCA1,BRCC3,BMI1,MAD2L2,ANAPC4,RING1 |
| 1.192e-04 | -9.03 | anchoring junction | cellular component | GO:0070161 | 491 | 91 | 17570 | 2233 |
ARHGAP26,ACTG1,ACTR3,RPS29,DDR2,MYH9,CD99L2,ENAH,GIT2,HSPA1A,FLNB,DST,ESAM,RPS16,JAG1,PPFIBP1,MMP14,VCL,PERP,PTPRK,FLNC,DSC3,PHLDB2,TNK2,EVL,LIMA1,PTPRM,HSPA5,AKAP12,VIM,PNN,CAV1,DSP,NUP214,RAB10,CXADR,ARPC3,RHOU,AHNAK,MISP,ITGA2,DPP4,ADAM9,NFASC,MAGI1,NRP1,PARD3,LPP,CADM4,EFNB2,JUP,TRIP6,NHS,LAMTOR3,SMAD7,EVPL,CD226,MCAM,PVRL3,DSG2,ANXA5,RDX,CD44,PABPC1,PNMA1,CAV2,SPTAN1,PPP1R9B,PXN,TPM4,ASAP3,FERMT2,LIG4,ATAT1,PTPN12,PTK2,PALLD,PEAK1,ANXA1,HSPA1B,CAT,PDLIM1,DSC2,MPP7,SRP68,FAT1,SNAP23,SVIL,ADGRE5,CASS4,PRKAR2A |
| 1.200e-04 | -9.03 | SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP | MSigDB lists | SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP | 25 | 11 | 17758 | 2279 |
LSS,MVK,IDI1,SREBF2,INSIG1,ELOVL6,FDPS,SQLE,DHCR7,FOXC1,FDFT1 |
| 1.207e-04 | -9.02 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | 85 | 24 | 17758 | 2279 |
EFNB2,CGN,INSIG2,ZFYVE1,PPARG,PDK4,ARID5B,GTF2IRD1,PBX1,ATXN1,RNF43,SEMA3E,MEF2D,ATP8B2,TGFB2,TCF7L2,RERE,DDIT4,SMAD3,ALAD,ZKSCAN1,NRP1,CDK6,PTPRK |
| 1.209e-04 | -9.02 | CACCAGC,MIR-138 | MSigDB lists | CACCAGC,MIR-138 | 213 | 47 | 17758 | 2279 |
PTP4A1,YDJC,FEM1C,IGF2BP2,RSF1,SLC6A8,PSMF1,PDE3A,AHCYL2,ANKRD54,PTPN2,SH2B3,NEBL,SCN1B,DNAJB6,JAZF1,NBEA,JOSD1,CALN1,DENND1A,SEH1L,CLK2,ELOF1,SOBP,MSI2,ZCCHC14,ADAMTSL3,KCNMA1,ARRDC3,JMJD1C,TPM4,USP10,FERMT2,COTL1,PTK2,CORIN,SOX4,ERC1,CLNS1A,DHX57,TSR1,UBAP2,LSM14A,L3MBTL3,IQSEC2,SMG1,KAT6A |
| 1.228e-04 | -9.01 | GRADE_COLON_AND_RECTAL_CANCER_UP | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_UP | 273 | 57 | 17758 | 2279 |
USP7,WDR75,DNAJC2,HM13,WDR74,OLA1,AARS,DDIT4,NOP56,AMPD3,EIF2S2,SRSF2,NEBL,ERI1,INTS7,ATIC,MCM5,MYC,TIMELESS,ANXA5,RAN,S100A14,CD44,FBL,PPA1,PERP,MBTPS2,MTHFD1,FDFT1,TTPAL,GARS,NOL8,LDHA,PSMA1,PTPN12,PSMG1,MARS,SHISA5,MCM2,ABCF1,UBR4,TARS,SH3GL1,EPRS,DNTTIP1,PXDN,MTHFD2,SYNCRIP,KPNA3,TRAP1,DNAJA3,NSMCE2,SET,CCDC85B,RBM26,PFDN2,GCSH |
| 1.235e-04 | -9.00 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP | 184 | 42 | 17758 | 2279 |
FBXO45,URB2,CAMK1,HSD17B10,SLC25A12,PPIL1,TUBB6,POP5,IKBIP,TTI1,STAM,EDC3,FLAD1,RNF141,HVCN1,COPS4,YLPM1,CWC27,ERI1,PMPCA,GPATCH1,POLR3B,GTF3C3,CORO1A,HCFC2,SNAPC5,TSHZ1,WDR36,ITPA,C11orf49,PTK2,IMPDH2,RPA1,KIF16B,PEX1,FBXO21,SMARCC1,KIDINS220,ARHGAP12,UMPS,RUNX1,AP2S1 |
| 1.238e-04 | -9.00 | MORF_RFC5 | MSigDB lists | MORF_RFC5 | 75 | 22 | 17758 | 2279 |
CHD9,GTF2H3,EP400,SIGMAR1,ATRX,POLA1,SLC2A1,NFX1,BRCA1,TTI1,EIF5B,TAF2,ZNF330,MYC,NCKIPSD,SYNJ2,NFRKB,TAF12,RUNX1,CEP135,MUTYH,SMG1 |
| 1.241e-04 | -8.99 | SET_dom | interpro domains | IPR001214 | 51 | 17 | 18293 | 2341 |
ASH1L,KMT2D,SETD1B,KMT2E,PRDM16,SETD2,EHMT1,PRDM1,KMT2C,SETD7,NSD1,EHMT2,SUV39H2,SETD5,KMT2A,SETD6,SMYD3 |
| 1.242e-04 | -8.99 | WINTER_HYPOXIA_METAGENE | MSigDB lists | WINTER_HYPOXIA_METAGENE | 231 | 50 | 17758 | 2279 |
MPI,AK2,FN1,EGR1,CLK1,SLC2A1,ID2,BHLHE40,SLC6A8,HMOX2,BIRC2,DDIT4,MMP7,STC2,ANXA5,PTGS1,MET,ERRFI1,LONP1,ANGPT2,NT5E,PFKFB4,SLC6A16,SLC3A2,COL5A2,PPAT,HSPA5,LDHA,LGALS1,VIM,PNN,DKC1,ODC1,ANGPTL4,HERPUD1,ANXA1,BATF3,PLIN2,INSIG1,HIF1A,TIMM17A,HK2,RIOK3,TBPL1,SGSM2,SLC16A1,UMPS,ANXA2,RBPJ,DDIT3 |
| 1.242e-04 | -8.99 | V$YY1_02 | MSigDB lists | V$YY1_02 | 231 | 50 | 17758 | 2279 |
PRPF38B,ASH1L,PCNT,PRKCSH,WDR13,MYNN,AKT1S1,DNAJC22,ENOX1,GBF1,FOXO3,UBR5,GIGYF2,KDM2A,ANAPC10,SELT,ZFP37,LYPLA2,SERBP1,DEAF1,PTBP2,TUBA1A,MIOS,AP4S1,KIAA1143,POLK,KIF15,TOP3A,COL4A3BP,POU2F1,SNAP25,DENND4A,RAB10,NCDN,EXOC6,UBTF,DYRK1B,GTF2A1,ADNP,ZZEF1,LUC7L3,POLR3E,GLG1,HIC2,PPP1R12B,RBM26,NCOR1,BRSK2,ADK,N4BP2L2 |
| 1.247e-04 | -8.99 | DNA_METABOLIC_PROCESS | MSigDB lists | DNA_METABOLIC_PROCESS | 255 | 54 | 17758 | 2279 |
POLB,XPC,ATRX,DBF4,ATF7IP,MLH1,RPAIN,SMARCB1,TERF2IP,ABL1,ACD,MCM5,XRCC2,GTF2H1,RAN,POLE3,MSH4,NT5M,OGG1,TERF2,NT5E,RFC4,PMS1,RFC3,PRIM2,APEX1,KRT7,POLK,POLA1,SMARCAD1,NOL8,TSN,LIG4,APTX,BRCA1,MCM2,DKC1,POLG2,RAD54B,RPA1,EXO1,RBBP8,KPNA1,BRCA2,GADD45A,POLE2,SET,ORC5,MSH3,RAD51B,ALKBH1,ATM,XRCC4,MUTYH |
| 1.255e-04 | -8.98 | ovary-carcinoma | COSMIC cancer mutations | ovary-carcinoma | 962 | 162 | 17775 | 2278 |
FEM1C,NF1,ATRX,AARS2,TRPM6,CSNK2A1,SBF2,RNF43,HLTF,STK33,PRKCA,AARS,SNAPC4,MAP2K3,SLC30A7,SMARCB1,DST,ABL2,SRSF2,NEK6,THAP4,UBAP2L,CDK6,PRKACB,CARM1,SRPK2,SF3A1,TNK2,NRAS,SKIV2L2,CDK4,TCEB3,CUX1,KSR2,ABCC2,BRCA1,SGK2,KMT2C,STOML2,DYRK1B,TCF7L1,BRCA2,TRRAP,EIF4ENIF1,DNAH2,RIOK1,RUNX1,CCNB1IP1,COPS6,DMTF1,PTPN14,HERC2,EP400,TAF1,CLK1,TRIO,PIK3R4,RLF,PHGDH,TGFBR2,PRKCE,APLF,USPL1,COPS3,ATXN2,PPIL2,MAP3K12,LRP3,SIK3,DDX28,BDNF,CAMKK2,KCNQ3,RREB1,ZNF512B,OBSCN,RNH1,ZNFX1,PRDM1,SYT1,MBNL2,APBB3,TRAP1,RIOK3,PPP1R12B,TBCK,MAP2K4,TRERF1,CELSR3,PDK4,DDR2,SMARCA4,RIPK1,TMEM104,ISG20L2,RIOK2,ZC3H13,CAD,VPS18,PRKD3,SOCS1,RPS6KL1,IKBKB,CLCN6,HIRIP3,ADCK4,MET,KMT2A,CDK12,BRD4,PDK1,ZNF480,SATB2,STK10,FGFR1,EXO1,CAMK2D,CDC16,ADNP,HIPK2,ZNF333,RPS6KB1,TSPAN5,SMG1,BCKDK,NCOR2,TNIK,BRAF,MAP3K13,DYM,CAMK1,PDE4B,CLSTN2,CCDC7,MLH1,CSNK1A1,RMI1,PRKCH,ABL1,SACS,RDX,PLEKHG4,HSD17B12,CLK2,RPS6KB2,SPTAN1,PSMC3IP,ARHGAP39,TEX14,OXSR1,SRCAP,TRIB3,MSH3,SVIL,ATM,GPAM,PREPL,RPS6KC1,ZAK,GPATCH4,IPO4,STK4 |
| 1.268e-04 | -8.97 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | 190 | 43 | 17758 | 2279 |
TTN,LYRM4,LRRC28,NDUFB5,HSD17B10,TRAK1,NHS,SPATS2L,SLC9B2,FOSL2,INPP1,STAM,FDX1,EIF2S2,MBD2,FGGY,SOCS6,RDX,B3GNTL1,ITGAX,YARS,GNG5,FDFT1,PAQR6,ARNTL2,ANTXR2,ZFYVE1,STAMBP,CLYBL,EIF3J,RDH10,TPM4,PRDM1,EVI5,SLC39A14,CAMK2D,NME7,ADAT2,IRAK2,SQLE,DPP4,HS2ST1,LPP |
| 1.268e-04 | -8.97 | GSE27786_NKCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_NKCELL_VS_NKTCELL_DN | 190 | 43 | 17758 | 2279 |
USP7,PCNT,LRRC28,MRI1,TMEM177,TMEM104,PHGDH,CD226,MFHAS1,FAM8A1,NOP56,UBR1,DHX33,SCAF1,DTNBP1,ZEB1,POLR1B,KIAA0922,GMDS,FXN,TMEM200A,MTHFD1,C21orf58,ANTXR2,FAM172A,PDK1,VWCE,ZNF512B,TRIM37,TTC28,ZNF251,MFN2,SLC39A14,PES1,ZNF622,DNAJC1,CHD3,NSMCE1,POLR3E,EXOC4,WDR66,PRKAR2A,SMG1 |
| 1.271e-04 | -8.97 | PMS1 (PMS1 homolog 1, mismatch repair system component) | protein interactions | 5378 | 51 | 18 | 16036 | 2270 |
HERC2,RFC4,PMS1,MCM6,CYLD,FAN1,SBF2,RANGAP1,MLH1,UBR5,UBC,EXO1,BRCA2,CCNT1,CDK9,UBAP2L,POLR1C,TOP1 |
| 1.271e-04 | -8.97 | SPTBN1 (spectrin, beta, non-erythrocytic 1) | protein interactions | 6711 | 97 | 28 | 16036 | 2270 |
DBN1,TNIK,FN1,ANK2,DDX19A,SIRT7,HSPA5,ZNF512B,POU2F1,CSNK2A1,ATF7IP,TNKS1BP1,PLCB1,RPA1,SNCA,SMAD3,SHC1,SREBF2,MCM5,COPS5,SVIL,CEP63,TPM1,TXN2,SRRM2,AGO3,MEF2C,SPTAN1 |
| 1.281e-04 | -8.96 | MODULE_72 | MSigDB lists | MODULE_72 | 304 | 62 | 17758 | 2279 |
MPI,MCM6,TRIM16,UBXN1,MAPK8IP3,KIF5C,CSNK2A1,SMARCA4,ZIC2,GYG1,HMOX2,SAFB2,BIRC2,KDM1A,HDDC2,CHN1,SNW1,SRSF2,ACD,COPS3,SEC24C,GSTA4,SSBP1,MFAP2,POLE3,SERPINH1,PEG10,SRRM2,TOMM34,ATP6V0D1,TRIP13,SF3A1,FADS1,PRAME,ZCCHC14,RBCK1,KDM5B,TSPYL4,CRIM1,PARP2,WBSCR22,PTPN12,AKAP12,PSMG1,RANGAP1,CAV1,MCM2,FGFR1,CXADR,APBB3,HPRT1,NSF,LSM14A,FAT1,ARL4A,COPS5,CEBPZ,CFD,NFKBIB,TPM1,TROVE2,RBP1 |
| 1.289e-04 | -8.96 | VCP (valosin containing protein) | protein interactions | 7415 | 562 | 111 | 16036 | 2270 |
BCCIP,DNM3,CUL7,CUL4A,NF1,RBFOX2,AP1B1,SEC16A,TNKS1BP1,UBR5,EEA1,GBF1,HSPA1A,FLNB,TOM1L1,SLX4,PPFIBP1,WAC,NBEA,RNF2,MSH4,VCL,SRRM2,PRMT3,AUP1,CDC37,PRPF19,KDM3B,ARHGAP17,DTNB,TRIM13,SLC3A2,SESN2,RFC3,CDK4,RAB7A,HSPA5,ATXN1,VIM,CAV1,BRCA1,SON,DSP,UBR4,RAB10,VPS53,TIMM44,RANBP2,SMARCC1,INSIG1,TP53BP1,COPS5,ABCC3,PRPF4,FUS,HEATR1,ANXA2,MDN1,TXN2,NMD3,TMEM33,INSIG2,FN1,SUPT6H,PRPF31,SIRT7,UBXN1,H2AFJ,GIGYF2,BZW2,CTNNBL1,ANXA7,COPS3,ZNF326,TNPO3,ANXA5,VAPB,RDX,GTF3C3,ALDH18A1,PRMT5,TOMM34,TERF2,TOP1,SPTAN1,HMGCR,NIPSNAP1,EIF4A2,WBSCR22,PSMA1,USP10,FERMT2,CAAP1,SYMPK,NCDN,HERPUD1,ARIH2,ISG15,UBC,ATXN7,INF2,TPD52L2,NSF,HIF1A,HNRNPH3,CUL2,NAPA,BRSK2,PRKAR2A,IPO4,COG5 |
| 1.297e-04 | -8.95 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | 196 | 44 | 17758 | 2279 |
DCTN3,IMMP2L,ADAM19,DROSHA,CELSR1,ALG8,OLA1,AARS,NOP56,GART,NOP16,BANF1,BUD31,METTL8,GMDS,TIMM50,NT5E,PTPRK,MTHFD1,METTL1,DPF3,UPP1,ELOVL6,ATOX1,UTP15,ADSL,MRPS10,MARS,HSH2D,GSTCD,ARRDC4,ZNF467,CYB5B,C8orf33,NOP58,VPS53,INF2,RARS,POLE2,NSMCE2,FDPS,EIF2B3,RBP1,GCSH |
| 1.297e-04 | -8.95 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 196 | 44 | 17758 | 2279 |
SLC12A7,EGR1,XPC,WDR74,SMAD7,SBF2,ZFP36L1,VARS,SSBP2,FOXP1,NOP56,SKI,ENTPD5,RABGAP1L,MYC,FBL,CNOT4,PRMT3,LONP1,ANTXR2,EVL,ATF4,SLC3A2,PDK1,RREB1,POU2F1,RABAC1,IL6R,KLF6,MAT2A,RERE,FBXO21,TSR1,GADD45A,STX1A,TP53BP1,KLF4,PER1,D2HGDH,PAM,FNTB,GALNT10,RPS6KC1,IPO4 |
| 1.302e-04 | -8.95 | DNA_REPLICATION | MSigDB lists | DNA_REPLICATION | 101 | 27 | 17758 | 2279 |
RFC4,POLB,PMS1,RFC3,KRT7,PRIM2,POLA1,NOL8,DBF4,MLH1,MCM2,DKC1,POLG2,RPAIN,RPA1,TERF2IP,EXO1,ABL1,POLE2,MCM5,ORC5,SET,MSH3,POLE3,NT5M,MUTYH,TERF2 |
| 1.315e-04 | -8.94 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | MSigDB lists | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 329 | 66 | 17758 | 2279 |
CDCP1,CYLD,TRIM16,TNFRSF21,MYH9,GRINA,SSBP2,TMEM132A,ARSJ,FDX1,MAP2K3,AMPD3,MPHOSPH10,RELB,PEG10,ETV1,FXN,HTRA2,MALL,PPARG,C1QTNF1,HSPA5,SOX4,STK10,CCDC28B,CXADR,GNAI1,VDR,SMAD3,GATA6,ITGA2,SYNGR2,HSPB8,TRAF3,MED20,TMEM158,MID1,MEF2C,CARS,VIPR1,TNIK,B4GALT5,TRIO,RCAN1,BHLHE40,PHLDA2,MTUS1,PDE10A,TANK,SAMD4A,ARNTL2,ADARB1,DNMBP,PDE4A,ARID5B,NXN,KLF6,TCF7L2,NR2F1,INF2,SRCAP,TRIB3,GADD45A,VCAN,NR2F2,PDLIM5 |
| 1.332e-04 | -8.92 | nucleoside phosphate metabolic process | biological process | GO:0006753 | 450 | 86 | 16441 | 2138 |
NDUFA5,SUCLG1,ATP6V1A,NDUFB5,OLA1,NT5C3A,COX10,PUDP,HSPA1A,PDE3A,NDUFB3,FLAD1,CAD,AMPD3,ATP5G2,PPCDC,MYH3,NT5C,ME1,FHIT,CMPK1,NDUFA6,FXN,MTHFD2L,OGG1,MCEE,GARS,ITPA,UPP1,DLG4,ATP6V0A1,NUDT15,DLST,PDE8B,ATP5D,STOML2,SNCA,HPRT1,DCXR,G6PD,MUTYH,AK2,SULT1C2,AK6,PDE4B,CHCHD10,APRT,RNASEH2B,NDUFS7,NAMPT,DCTPP1,GART,NDUFV1,ENTPD5,PDE10A,ATIC,NT5M,PRPS1,NT5E,HMGCR,MTHFD1,PFKFB4,BDNF,PDE4A,PPAT,SMARCAD1,IDH3G,LDHA,SULT4A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,PGD,CAT,NME7,COQ9,HK2,TBPL1,SURF1,UMPS,NDUFS5,BPNT1,ADK,PDE9A |
| 1.338e-04 | -8.92 | HALLMARK_FATTY_ACID_METABOLISM | MSigDB lists | HALLMARK_FATTY_ACID_METABOLISM | 156 | 37 | 17758 | 2279 |
AOC3,AUH,CCDC58,PRDX6,SUCLG1,UROD,HSD17B10,PTPRG,DECR1,IDI1,S100A10,SUCLG2,ME1,HIBCH,MGLL,MCEE,ACSL5,ACADS,APEX1,IDH3G,CPOX,LDHA,LGALS1,ADSL,RAP1GDS1,ODC1,DLST,CPT1A,ECH1,RDH11,RETSAT,ETFDH,ALAD,SERINC1,HSDL2,ACOX1,D2HGDH |
| 1.348e-04 | -8.91 | TGGAAA_V$NFAT_Q4_01 | MSigDB lists | TGGAAA_V$NFAT_Q4_01 | 1781 | 279 | 17758 | 2279 |
LUZP1,DPH1,SBF2,UBR5,GABPB2,PDZD2,S100A10,NSRP1,PAK1IP1,CHD2,FUT11,CDK6,PPM1K,SPAG6,TBC1D8,DPF3,GDAP1,NRAS,NR6A1,VSNL1,NFIA,STOML2,DDX3X,SLC7A1,ARL6IP5,HIC2,XPNPEP1,RUNX1,TPM1,BMI1,BLMH,ZNF532,MEF2C,PRPF38B,CLDN15,SLK,OPHN1,DLGAP4,PID1,BTBD9,KCNJ14,ANXA10,SH2B3,TECTA,FAM192A,CHN1,RSPRY1,TSPAN2,DHX37,COPS3,CACNB2,PRMT5,HMGCR,ZNF675,BDNF,RREB1,ALG6,STAG1,AOC2,KIAA0586,ST6GALNAC3,SNAP25,ARRDC4,PLCB1,MBNL2,EHBP1,TRIM37,ARIH2,NCDN,PHF6,RDH11,LRP1B,EHMT2,HIF1A,ZZEF1,CDK9,VCAN,PDLIM5,AMOTL1,TRERF1,ATP6V1A,NPAS2,ZBTB37,PDK4,MAB21L3,DDR2,NECAP1,TUBB6,ZNF827,SHC1,VGF,WAC,LPIN2,MMP14,GSTA4,SERPINH1,MTIF2,EIF3J,LGALS1,SATB2,POLG2,HSD3B7,HTR7,ZFAND3,WDR5B,HOXA3,RAB30,HMGA2,UTP14A,B4GALT5,SLC25A12,ID2,FARS2,ATG2B,RCAN1,IP6K2,TGFB2,BHLHE40,GDPD5,MBNL1,GIGYF2,NEDD4,ABL1,ATXN7L1,PTRF,LRP2BP,UPF2,ZNF710,ERRFI1,FBXL19,C15orf41,ACTR3B,DIS3L2,NAV3,LSM12,AGPAT4,KCNMA1,R3HDM2,PDE3B,SRCAP,HNRNPH3,SVIL,BMP4,SLC43A1,NF1,PTPRA,RNF43,BCOR,MAP2K3,SLC30A7,ARHGAP18,PHKA1,MARVELD2,SLC39A7,ANAPC11,YARS,ETV1,VPS13B,SRPK2,DBN1,FLNC,DEAF1,AEBP2,GCNT2,ZNF124,ARRDC3,KSR2,COTL1,KRTCAP2,ZNF91,C1orf122,BSN,PEX1,CCDC3,GLS,ZNF622,GATA6,TP53BP1,TNFRSF1A,ADAM9,SEPHS2,PIGN,CHST11,FN1,DPF2,PCSK7,ZIC2,ZFP36L1,PHGDH,ARID1B,MCAM,WDR27,PRF1,IFT43,TRA2A,JMJD1C,TBXAS1,PSMA1,ZNFX1,PRDM1,ISG15,UBE2E1,VAC14,NAP1L5,SPAG9,SYNCRIP,KIAA0355,SLC16A1,TMEM117,ZNF430,TBL1X,PTP4A2,TCF12,DLL4,RBFOX2,TNXB,SSBP2,SPATS2,TNKS1BP1,SEMA6A,PLXNB1,CAD,BRE,JAG1,PPFIBP1,CYB5D1,SLC38A2,MAML3,SOBP,TUBA1A,KIRREL2,RAB7A,GRHL3,ATXN1,VIM,USP36,WARS,TJAP1,EXO1,SMAD3,HYAL3,ITGA2,ZNF436,SRFBP1,FAHD1,TSPAN5,NSUN6,VPS45,PDE4B,FOXP1,ENOX1,HIST2H2AB,POGZ,BMP6,BZW2,MAN1A1,PRKCH,DCTN4,GREB1,FBL,HSD17B12,PCSK6,IL11RA,AP4S1,ADAMTSL3,TEAD1,ZNF654,PSMC3IP,ANKMY2,ARHGEF12,ZNF407,NAALADL2,RERE,CACNB1,GADD45A,TBX3,VPS37B,RBM26,TATDN1 |
| 1.359e-04 | -8.90 | CPSF1 (cleavage and polyadenylation specific factor 1) | protein interactions | 29894 | 60 | 20 | 16036 | 2270 |
CUL7,SMARCAD1,SIRT7,RANGAP1,MCM2,SYMPK,CDC73,NEDD4,POLR2A,RPA1,CHD3,COPS5,RRAGA,GTF3C3,TAF12,COPS6,WDR33,FIP1L1,CPSF3,CLK2 |
| 1.366e-04 | -8.90 | HIST1H1A (histone cluster 1, H1a) | protein interactions | 3024 | 158 | 40 | 16036 | 2270 |
NIFK,CUL4A,LIN28B,TAF1,SIRT7,FARS2,RSL1D1,PRKCA,RBM19,PARN,PSMF1,PELP1,HIST2H2AB,CDC73,PABPC4,TERF2IP,KRI1,PRKCE,CTR9,CDK6,ZC3H3,FTSJ3,AEBP2,WDR61,DDX24,CDK4,RSBN1,PRDM1,DKC1,DHX57,DOT1L,PAF1,POP1,TOE1,EHMT2,GADD45A,SET,RAD51B,C7orf50,ZC3H8 |
| 1.381e-04 | -8.89 | MARZEC_IL2_SIGNALING_UP | MSigDB lists | MARZEC_IL2_SIGNALING_UP | 112 | 29 | 17758 | 2279 |
PEA15,BCCIP,SPRED2,PDE4A,FGF2,PPAT,TNFRSF21,GNL3,DKC1,DLST,HSPA1A,PHLDA2,FGFR1,HSPA1B,TRIB3,GART,POLE2,SOCS1,MYC,HK2,CSRNP1,PTRH2,UMPS,PUS1,POLR1B,POLR1C,PDCD11,ZAK,BAG1 |
| 1.382e-04 | -8.89 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | 573 | 104 | 17758 | 2279 |
PPP2R2A,COX10,GBF1,BIRC2,BRE,COPS4,UCHL5,SLC38A2,ETF1,ZNF148,TTC3,POLE3,CMPK1,YARS,PRKACB,LYST,SF3A1,TRIM13,GARS,SKAP2,SLC38A1,ITPA,LIMA1,SFSWAP,MTIF2,TCEB3,GMFB,ATXN1,SUMO3,MCL1,PITPNB,MCM2,ZNF91,ODC1,SON,TPK1,STOML2,MLLT10,CDC16,TIMM17A,ALKBH1,XPNPEP1,PRPF4,ANXA2,CCNB1IP1,BRCC3,EIF2B3,NOLC1,NMD3,BAG1,MEF2C,SLC12A7,DCTN3,SARS,SCAMP3,LAMTOR3,PDE4B,ARFIP2,FARS2,MLH1,CSNK1A1,SLC1A1,TTC1,ADH5,EIF2S2,DCTN4,GEMIN4,PRMT5,PRPS1,PNMA1,PPA1,HSD17B12,C12orf4,SCAF11,CAMKK2,DDX24,ALG6,GPHN,CRADD,FZD3,PSMA1,TBRG4,PTPN12,GPNMB,KLF6,PDE3B,UBE2K,NEU1,RERE,CAT,OXSR1,PWP1,ALG5,SPAG9,NSF,UBAP1,RIOK3,GLG1,EIF2S1,RBPJ,PSAP,NAPA,PDLIM5,KAT6A |
| 1.385e-04 | -8.88 | Znf_RING/FYVE/PHD | interpro domains | IPR013083 | 438 | 83 | 18293 | 2341 |
MYCBP2,ASH1L,PHF3,ATRX,KMT2E,RCHY1,RNF24,RNF43,HLTF,EEA1,RING1,TRIM66,KDM2A,LONRF2,ZFYVE28,UBR1,ANAPC11,RNF111,INTS12,TTC3,RNF2,KDM5C,KMT2A,PRPF19,DPF3,PCGF3,TRIM13,KMT2D,RBCK1,BAZ2A,MARCH6,BRCA1,KMT2C,MLLT10,BSN,BAZ1A,RBSN,KDM4B,RAD18,SH3RF1,CHD3,NSMCE2,TRAF3,RNF130,BMI1,MID1,ZNF598,RNF214,TRIM36,DPF2,MEX3A,TRIM15,RSF1,TRIM22,CHD5,SPIRE1,RNF141,RSPRY1,RNF40,RNFT2,TAF3,PPIL2,LTN1,FBXL19,LRSAM1,CNOT4,MARCH9,SCAF11,KDM5B,ZFYVE1,WDFY3,USP49,KDM5A,MEX3B,TRIM37,ARIH2,NSD1,BAZ2B,RNF138,USP20,KDM4C,KAT6A,RNF114 |
| 1.387e-04 | -8.88 | Transcription of the HIV genome | REACTOME pathways | R-HSA-167172 | 67 | 21 | 8202 | 1117 |
GTF2H3,TAF1,GTF2H2C,RNMT,AK6,TCEB3,NELFA,SUPT5H,POLR2A,TAF9B,TAF2,ELL,SUPT4H1,GTF2A1,TAF3,CCNT1,CDK9,TAF4,GTF2H1,NCBP2,TAF12 |
| 1.403e-04 | -8.87 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 185 | 42 | 17758 | 2279 |
BANP,GGT1,ASCC1,BRAF,MAP3K13,PDE4B,GRINA,BCOR,NBEAL1,VPS18,AMPD3,SETD5,CFDP1,PPCDC,CHD2,LPCAT1,FUT11,CDC37,BRD4,SLC3A2,PDK1,DDX41,RREB1,KDM5B,LSM12,ATG12,MAPK1IP1L,ARL5B,SERP1,ABCF1,GZF1,ZBTB25,ZC3H12A,SKIL,SEC31A,OXSR1,SPAG9,INSIG1,TRAF3,RBPJ,NAPA,DDIT3 |
| 1.403e-04 | -8.87 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 185 | 42 | 17758 | 2279 |
KLHL24,USP7,MYCBP2,MINK1,EIF3C,PRKAB2,TRAK1,MYH9,PBX1,SMG7,KIF5C,CD99L2,RSF1,CSNK1A1,SAFB2,FOXP1,FAM49A,POM121,FLNB,SKI,ZNF804A,ASAP1,SYN2,LPIN2,ANKRD11,SLC25A23,PTPRK,SOBP,R3HDM1,DLG4,LENG8,SETD7,NCDN,BSN,DOT1L,GNAI1,RHOU,UBTF,CLEC16A,SPOCK2,STK4,MEF2C |
| 1.406e-04 | -8.87 | positive regulation of macromolecule biosynthetic process | biological process | GO:0010557 | 1634 | 261 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,GABPB2,LPIN1,SKI,SREBF2,ZFHX3,WIZ,RNF111,ZNF148,MEIS3,DDN,HMBOX1,NR6A1,GNL3,NFIA,TCEB3,CUX1,SUPT20H,STOML2,DDX3X,BRCA2,SUPT4H1,CCNT1,RUNX1,RFXAP,MEF2C,BANP,EPM2AIP1,EGR1,JUP,KHDRBS1,SIRT7,PID1,RSF1,CDC73,MYC,MED24,PABPC1,MYB,GTF2H3,BDNF,WDR61,STAG1,RREB1,PRDM16,ARID5B,SMARCD3,ARID1A,NELFA,PLCB1,TRIM37,ONECUT2,ABCF1,IRS1,CAT,TASP1,HIF1A,CDK9,SPEN,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SHC1,ACD,WAC,LPIN2,KMT2A,KMT2D,BRD4,SATB2,MED16,MEF2D,SETD7,ERC1,SERP1,VDR,TAF2,SMARCC1,HIPK2,RPS6KB1,HMGA2,INSIG2,TCF3,ID2,TRIM22,TGFB2,RPS6KA5,FOXO3,MAD2L2,SFR1,TADA3,SNW1,TRIAP1,YBX3,LARP4B,SAMD4A,SOX6,MBTPS2,SLC40A1,IL6R,KLF6,GUF1,FOXC1,UBC,POLR2A,NSD1,ARID3B,BMP4,IGBP1,UQCC1,DDIT3,KAT6A,TRIM16,ATRX,KMT2E,GPBP1L1,AAMDC,PPARGC1B,SIRT2,MAP2K3,SMARCB1,PHF5A,DHX33,ZEB1,RELB,RAN,ETV1,TRIM14,ZBTB17,DEAF1,TRIM13,ATF4,RBCK1,PPARG,CDK4,HSPA5,BRCA1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,TNFRSF1A,DLX2,CLU,ZC3H8,UQCC2,FOXO1,TAF1,PAX2,SMAD7,TRIM15,ZIC2,BARX2,RLF,ARID1B,NAMPT,SUB1,ELL,CEP290,BUD31,CTR9,GTF2H1,ICE2,NRIP1,CAMKK2,PAXBP1,UTP15,EIF2A,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,ZFP90,TBL1X,TESC,TCF12,ASH1L,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,NRF1,RRN3,JAG1,CAMTA2,NVL,IKBKB,MET,CTC1,MAML3,MOSPD1,KAT8,DDX41,GRHL3,ATXN1,DKC1,SMAD3,IKZF4,SIX5,KLF4,COPS5,CEBPZ,ARNTL,HEATR1,PUS1,PKIB,DNAJC2,MAP3K13,SUPT6H,CAMK1,AGO2,ATF7IP,BMP6,PRKCH,HAS3,UTS2,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,ZNF821,FGF2,KDM5A,SMARCAD1,MEN1,HSPA1B,MKX,RERE,TBX3,TAF4,BCAS3,CSRNP1,FNTB,NCBP2,TAF12,RBPJ,MYRF,NR2F2,NFKBIB |
| 1.407e-04 | -8.87 | PostSET | smart domains | SM00508 | 17 | 9 | 9131 | 1249 |
NSD1,ASH1L,KMT2D,SETD1B,SUV39H2,EHMT2,SETD2,KMT2C,KMT2A |
| 1.412e-04 | -8.87 | PRPF40A (PRP40 pre-mRNA processing factor 40 homolog A) | protein interactions | 55660 | 174 | 43 | 16036 | 2270 |
SART1,CUL7,FN1,UTP14A,DDX18,ZCCHC8,SIRT7,SF3A3,CSNK2A1,ENAH,JMJD6,PDCD7,RLF,TERF2IP,ZFHX3,YLPM1,FMNL1,SDCBP2,VCL,SRRM2,FMNL2,CDK12,HNRNPM,TERF2,SRPK2,SF3A1,SNU13,FMNL3,BRD4,EVL,AKAP8L,TRA2A,NPM3,FRA10AC1,PNN,UBE2K,SON,UBR4,RPA1,ZBTB8OS,CHD3,HNRNPR,COPS5 |
| 1.437e-04 | -8.85 | GSE27786_CD8_TCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_MONO_MAC_UP | 191 | 43 | 17758 | 2279 |
RWDD1,KHDRBS1,JMJD6,ATF7IP,MBNL1,FLNB,ADH5,SACS,UBE3A,ATP5G2,APLF,TAF3,BANF1,PAK1IP1,C16orf58,SUCLG2,RNF2,ZNRD1,HN1,FAM120B,NARS2,AEBP2,DDX24,C2orf76,SETD2,SLC35G1,ADSL,MEF2D,ANGPTL4,ACOXL,C20orf196,SUFU,DUS3L,SMARCC1,ZBTB8OS,TP53BP1,DNAJA3,NCOR1,FAM118A,IGBP1,IPO4,STK4,HS2ST1 |
| 1.442e-04 | -8.84 | posttranscriptional regulation of gene expression | biological process | GO:0010608 | 432 | 83 | 16441 | 2138 |
ZNF706,EIF3C,LIN28B,PRKCA,AARS,HSPA1A,PAIP2,ETF1,RAN,CDC37,ATF4,GCNT2,EIF4E3,EIF3J,CDK4,MTIF2,CAV1,SOX4,ENC1,NUP214,SERP1,PUM3,EIF3H,YTHDF2,DDX3X,SMAD3,EIF4ENIF1,DNAJC1,LSM14A,EEFSEC,PER1,RPS6KB1,EIF2B3,UQCC2,NOCT,TNRC6A,MIF4GD,DROSHA,LARS2,KHDRBS1,AGO2,IGF2BP2,VARS,ZFP36L1,PARN,GIGYF2,PSMF1,FOXO3,IGF2BP3,GATC,ATXN2,SELT,CELF1,IGF2BP1,EXOSC4,YBX3,LARP4B,PABPC1,SAMD4A,SERBP1,RPS6KB2,EXOSC2,APEX1,XPO5,EIF4A2,PSMA1,EIF2A,EIF5B,GUF1,ABCF1,UBC,CTIF,EPRS,IREB2,SYNCRIP,TRAP1,SET,EIF2S1,DTD1,NCBP2,CNOT6,UQCC1,AGO3 |
| 1.442e-04 | -8.84 | centrosome | cellular component | GO:0005813 | 474 | 88 | 17570 | 2233 |
RTTN,CUL7,ID1,RAB11FIP4,CYLD,PCNT,PAFAH1B1,OLA1,MKS1,TUBE1,TBCCD1,CSPP1,SIRT2,PIBF1,HSPA1A,RPGRIP1L,SKI,BLOC1S2,XRCC2,MAD1L1,RAN,CEP63,CEP135,CDK6,PRKACB,CEP128,EYA3,KIF15,ARHGEF10,CAMSAP2,EFHC1,TTC28,UBR4,CCDC28B,GNAI1,DDAH2,IFT81,CDC16,BRCA2,RAD18,IKZF4,CHD3,G6PD,CCDC146,PQBP1,IFT140,TSEN2,XRCC4,CEP170,DCTN3,HERC2,IFT57,KIZ,PAX2,DPF2,PDE4B,SMAD7,ID2,CEP126,CSNK1A1,MBNL1,SFI1,CEP164,CEP290,DCTN4,FBXO31,ATP6V0D1,CEP83,TTLL5,VPS37A,APEX1,CEP295,RAP1GAP2,HAUS6,KIAA0586,PSMA1,CCDC113,HSPA1B,DYNC1H1,KLHL22,NME7,WDR35,SDCCAG8,CCDC85B,USP20,SLC16A1,BRSK2,PRKAR2A |
| 1.446e-04 | -8.84 | negative regulation of cellular biosynthetic process | biological process | GO:0031327 | 1460 | 236 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,PRKCA,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,GPR87,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,ATF4,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,BRCA2,SUPT4H1,EIF4ENIF1,INSIG1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,TNRC6A,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,PID1,BARX2,ZIC2,RSF1,CDC73,ABCA7,IGF2BP3,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,IGF2BP1,PRMT5,NRIP1,LPCAT1,TERF2,MYB,ZNF675,GATAD2B,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,EPRS,MYBBP1A,SYNCRIP,EHMT2,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,AGO3,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,MAP2K5,CYLD,RBFOX2,SMARCA4,PBX1,PIBF1,RING1,KDM1A,PAIP2,ZBTB21,ACD,PPID,DNAJB6,RNF2,CTC1,CASP8AP2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,ENC1,FGFR1,PDE8B,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,EIF2B3,SETD6,YEATS2,HMGA2,DNAJC2,NOSTRIN,NCOR2,INSIG2,TCF3,AGO2,H2AFJ,NFX1,ID2,IGF2BP2,ATF7IP,GAS6,TRIM22,SOGA1,BHLHE40,RPS6KA5,FOXP1,GIGYF2,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,CELF1,YBX3,ERRFI1,SAMD4A,DMRT1,SOX6,CLK2,FGF9,MSX1,KDM5B,APEX1,PSPC1,FOXN3,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,ZRANB3,RERE,MKX,DKK1,TRIB3,NSD1,IREB2,TBX3,SET,EIF2S1,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 1.466e-04 | -8.83 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | 197 | 44 | 17758 | 2279 |
SLC12A7,SPRED2,HM13,EGR1,PRDX6,TTC27,FAM189B,DYM,SPRYD7,HSD17B10,SMAD7,SBF2,SSBP2,PTPRG,HSPA1A,NOP56,ELL,GART,SOCS1,MYC,BANF1,IKBKB,ANXA5,FBL,SRRM2,LYST,EVL,APEX1,CDK4,TMEM126A,LDHA,SHISA5,RABAC1,IL6R,KLF6,HSPA1B,PWP1,UBAP1,TP53BP1,KLF4,STX18,GALNT10,CNDP2,IGBP1 |
| 1.469e-04 | -8.83 | WANG_HCP_PROSTATE_CANCER | MSigDB lists | WANG_HCP_PROSTATE_CANCER | 107 | 28 | 17758 | 2279 |
FLNC,SYT17,SH2D3A,FN1,GLTSCR2,UBXN1,MAPK8IP3,WWC1,FOSL2,ST3GAL6,FOXO3,FGFR1,NAMPT,AHNAK,RPL28,NEBL,ABCA5,STC2,ZNF160,SOCS6,AEN,GTF2H1,SHMT2,NCOR1,PDLIM5,LONP1,SPTAN1,MORC2 |
| 1.470e-04 | -8.82 | PENG_GLUTAMINE_DEPRIVATION_DN | MSigDB lists | PENG_GLUTAMINE_DEPRIVATION_DN | 324 | 65 | 17758 | 2279 |
SRM,ADAM19,DDX18,TMEM109,PPP2R2A,ISG20L2,SLC29A1,NUP160,NOP56,CAD,FARSA,MPHOSPH10,IDI1,DNAJB6,UBAP2L,SSBP1,TRIP13,PRPF19,METTL1,KAT8,HSPA5,MARCKSL1,DKC1,ODC1,OSBPL1A,PES1,GLS,BAZ1A,HPRT1,SMARCC1,TIMM17A,CEBPZ,SYNGR2,SLC4A7,PRPF4,NOLC1,AK2,ALG8,VARS,PSMF1,SACS,NOP16,COPS3,FBL,LPCAT1,PRPS1,MTHFD1,RABEPK,FDFT1,NUDC,FAM98A,EXOSC2,LDHA,BMS1,RANGAP1,EIF5B,ABCF1,YIF1A,SYNCRIP,TRAP1,SQLE,EIF2S1,UMPS,DHCR7,GCSH |
| 1.473e-04 | -8.82 | GCM_MAP1B | MSigDB lists | GCM_MAP1B | 61 | 19 | 17758 | 2279 |
HERC2,SIK3,RBFOX2,ZFP14,KIF5C,TRIM37,FAM8A1,SPIRE1,EIF4ENIF1,SPAG9,KIDINS220,TMEM237,RABGAP1L,NISCH,DIRAS1,RAN,PREPL,CEP170,KIF1B |
| 1.473e-04 | -8.82 | RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY | MSigDB lists | RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY | 86 | 24 | 17758 | 2279 |
SCAF11,EXOSC2,EIF3C,PRPF31,SFSWAP,MTIF2,EIF3J,EIF4A2,SF3A3,EIF2A,DKC1,NOP58,EIF3H,PAIP2,NOP56,GEMIN5,ATXN2,CELF1,GEMIN4,EIF2B3,FBL,NOLC1,SRPK2,SF3A1 |
| 1.526e-04 | -8.79 | JmjC | smart domains | SM00558 | 32 | 13 | 9131 | 1249 |
KDM6B,KDM3B,HR,KDM5B,KDM4B,KDM2A,KDM5A,HSPBAP1,JMJD1C,MINA,JMJD6,KDM5C,KDM4C |
| 1.542e-04 | -8.78 | BOP1 (block of proliferation 1) | protein interactions | 23246 | 35 | 14 | 16036 | 2270 |
PES1,SNU13,GARS,CUL7,MYBBP1A,GTF2A1,GNL3,SIRT7,RNF2,ME1,FBL,NOP58,C18orf25,NOP56 |
| 1.542e-04 | -8.78 | TRMT6 (tRNA methyltransferase 6) | protein interactions | 51605 | 35 | 14 | 16036 | 2270 |
SNW1,EPRS,SNU13,DUS3L,UTP14A,HNRNPR,SKIV2L2,CBWD1,RDX,MARS,PUS1,PTK2,NAPA,NMD3 |
| 1.552e-04 | -8.77 | BROWNE_HCMV_INFECTION_4HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_4HR_DN | 245 | 52 | 17758 | 2279 |
PTP4A1,POLB,PRKAB2,NTSR1,PDE4B,SMAD7,PIK3R4,SLC25A12,PCSK7,ETFB,TOM1L1,ZNF239,SOCS1,NEBL,PHKA1,NVL,RABGAP1L,VAPB,MET,ERI3,ZNF710,ETV1,ZNF3,LYST,ZNF629,CLK2,KAT8,SKIV2L,RANBP6,DNMBP,MIOS,AP4S1,ZNF195,TFCP2,TFPI,GALK2,SON,KLF6,FOXC1,TMEM186,RDH11,SPOP,SMAD3,SLC7A1,GADD45A,UMPS,HMBS,RUNX1,NR2F2,PRKAR2A,DDIT3,MORC2 |
| 1.583e-04 | -8.75 | negative regulation of RNA metabolic process | biological process | GO:0051253 | 1261 | 207 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,PAF1,UBTF,SKIL,TCF7L1,SUPT4H1,SUFU,GATA6,CCNT1,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,BARX2,ZIC2,RSF1,CDC73,RNF40,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,PRMT5,NRIP1,PABPC1,MYB,ZNF675,GATAD2B,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,MYBBP1A,EHMT2,CDK9,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,CYLD,MAP2K5,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,ZBTB21,PPID,DNAJB6,RNF2,CASP8AP2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,PTBP2,SFSWAP,POU2F1,ATXN1,SATB2,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,SHQ1,TCF3,H2AFJ,NFX1,ID2,ATF7IP,GAS6,TRIM22,BHLHE40,RPS6KA5,FOXP1,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,YBX3,DMRT1,SOX6,FGF9,MSX1,APEX1,KDM5B,PSPC1,FOXN3,DHX34,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,RERE,DKK1,MKX,TRIB3,NSD1,TBX3,SET,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 1.592e-04 | -8.75 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_UP | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_UP | 186 | 42 | 17758 | 2279 |
FBXO45,NDUFA5,CAMK1,HECTD3,NAT10,WDR37,TUBB6,HMOX2,TGFBR2,LCLAT1,PITPNM1,ANKRD54,DDX56,SLX4,ZSWIM7,INTS7,NVL,MYC,PPCDC,PMPCA,PRPS1,SEH1L,SNX29,FAM98A,LAMC1,TSTA3,KIAA0586,BMS1,PTK2,ZNF850,ZNF251,ATP5D,SMARCC1,TIMM17A,COQ9,MKL2,SLC25A19,GPN1,C3orf35,GPAM,NCOR1,RUNX1 |
| 1.592e-04 | -8.75 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | 186 | 42 | 17758 | 2279 |
WDR74,ZCCHC8,SEC24D,URB2,ID2,CORO6,MLX,UCHL5,LTN1,RAN,C6orf89,TRIP13,TMPO,TNK2,MPP6,PSAT1,POLK,TSPYL4,EIF3J,HAUS6,ARHGEF10,MTHFD1L,CYB5B,ST3GAL5,RAD54B,STOML2,TMCO1,IFT81,HPRT1,ASCC3,ATAD5,HIF1A,AGTPBP1,EIF2S1,SLC16A1,RIOK1,ANXA2,HMBS,NOLC1,ADK,ZAK,TESC |
| 1.604e-04 | -8.74 | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | 628 | 112 | 17758 | 2279 |
PIGM,RAB11FIP4,CYLD,BIRC6,ATP6V1A,PAFAH1B1,RARS2,PDK4,OSBPL9,TMEM109,LPCAT3,FOSL2,PRKCA,ST3GAL6,SAFB2,DHX35,LPIN1,CIAPIN1,DECR1,BRE,ARHGAP18,DNAJB6,RABGAP1L,LPIN2,ME1,MET,TSPAN14,ZNRD1,SAP30,SLC3A2,FBXW4,WLS,EHMT1,GMFB,NOL6,ARHGEF10,LRRC8A,SHISA5,BRCA1,MEF2D,CA5B,SOX4,DCBLD2,MLLT10,PLIN2,IFT81,HPRT1,CAMK2D,AHNAK,DUS3L,PER1,PEMT,HIPK2,RAD51B,IFT140,ADAM9,PUS1,RFXAP,CEP170,ATXN7L2,USP15,PRPF38B,AK2,EGR1,ZHX3,LRRC28,ANKRD17,MRI1,HSD17B10,CENPB,KIF5C,MYNN,PLA2G12A,FOXP1,PSMF1,KRI1,PRKCE,ELL,NAV1,MYC,DCTN4,TIMELESS,ARHGAP1,GEMIN4,PRPS1,TOP1,FADS1,CRADD,POLK,TLE3,TMEM126B,ARHGEF12,YIPF3,IL6R,APTX,CHCHD6,ABCF1,ZNF708,SPAG9,UBAP2,UBAP1,WDR35,ZZEF1,COQ9,SDCCAG8,BIVM,BCAS3,EIF2S1,PURB,PTRH2,NCOR1,FNBP1L |
| 1.617e-04 | -8.73 | SUZ12 (SUZ12 polycomb repressive complex 2 subunit) | protein interactions | 23512 | 330 | 71 | 16036 | 2270 |
USP7,SART1,AMOTL1,PCNT,ACTG1,DDX18,PLRG1,NAT10,RSL1D1,SAFB2,HSPA1A,PABPC4,FLNB,ZC3H13,BCAS2,PHF5A,GLYR1,VGF,SLC39A7,RELB,RNF2,RAN,TIMM50,SF3A1,PRPF19,DBN1,GDAP1,SNU13,AEBP2,AKAP8L,LIMA1,BRCA1,DKC1,SON,STOML2,PYCR1,DDX3X,RANBP2,LUC7L3,SLC25A11,FUS,HEATR1,FIP1L1,NOLC1,PDCD11,LPP,KHDRBS1,SF3A3,SSR4,PHGDH,HIST2H2AB,DDX56,SNW1,EIF2S2,ZNF326,YBX3,FBL,MSI2,GATAD2B,PPP1R9B,TRA2A,KDM5A,UTP15,NOP58,DYNC1H1,EPRS,CDKAL1,PGAM5,PDLIM5,PRKAR2A,RNF114 |
| 1.625e-04 | -8.72 | KIM_ALL_DISORDERS_CALB1_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_CALB1_CORR_UP | 523 | 96 | 17758 | 2279 |
MYCBP2,NDUFA5,SYT17,ATP6V1A,PAFAH1B1,KIAA0232,PPP2R2A,NECAP1,GRINA,SYNJ1,AARS,SCAF8,KDM1A,RTN1,ASNS,IDI1,SRSF2,PPID,JOSD1,GSTA4,TTC3,RAN,YARS,PRKACB,SRPK2,GPM6A,GARS,FAM127A,NARS,GMFB,VSNL1,PCMT1,ATP6V0A1,CAMSAP2,OSBPL1A,GNAI1,HPRT1,HNRNPR,WDR7,AHNAK2,SLC25A11,AP2S1,TMEM158,CEP170,MAPT,VIPR1,DCTN3,SARS,AUH,SCAMP3,PRSS3,SLC25A12,RTN4,XPO7,BHLHE40,CLINT1,REEP5,FAM49A,MBNL1,CHN1,SUB1,NDUFV1,ANXA7,ATIC,COPS3,NDRG4,NRIP1,PRPS1,ATP6V0D1,AKAP11,TOMM34,HMGCR,TSPYL4,EIF4A2,RYR2,RABAC1,SNAP25,PDE2A,EHBP1,TRIM37,SYT1,UBC,NCDN,DYNC1H1,PWP1,SERINC1,NSF,STX1A,SET,RRAGA,EIF2S1,PSAP,PREPL,NAPA,DDX10,MAP2K4 |
| 1.626e-04 | -8.72 | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN | 192 | 43 | 17758 | 2279 |
C9orf78,UTP14A,PLRG1,ZIC2,FOXO3,SMARCB1,SLC25A20,PRKCH,MLX,INTS7,ZDHHC6,AP1M1,ANXA5,RNF2,PPA1,SEH1L,HNRNPM,RABEPK,MCEE,PDK1,PRIM2,PSAT1,ITPA,R3HDM1,GALK2,CCNDBP1,FOXRED1,CLNS1A,ARIH2,TIMM44,ZBTB25,SLC23A2,YIF1A,SRP68,COPS5,ARNTL,ORC5,DUSP19,EIF2S1,SLC4A7,HMBS,BLMH,FAHD1 |
| 1.626e-04 | -8.72 | GSE17721_12H_VS_24H_CPG_BMDM_DN | MSigDB lists | GSE17721_12H_VS_24H_CPG_BMDM_DN | 192 | 43 | 17758 | 2279 |
BCCIP,DCTN3,CDCP1,LUZP1,XPC,SEC24D,HSD17B10,LAGE3,CSPP1,LIAS,TGFBR2,PARN,PHLDA2,NDUFS7,MRPS30,ADH5,ATXN7L1,UBR1,ZDHHC6,LPIN2,TRIAP1,PAK1IP1,PCOLCE2,NDUFA6,SERBP1,MCEE,SCAF11,FADS1,ZNF124,VPS37A,TUBA1A,APEX1,WDFY3,ABCF2,RBM28,TMEM206,MSX2,ELP2,D2HGDH,EIF2S1,ABCC3,GPAM,IFITM2 |
| 1.650e-04 | -8.71 | methylation | biological process | GO:0032259 | 309 | 63 | 16441 | 2138 |
ASH1L,KMT2E,ATRX,NSUN6,ATF7IP,CHD5,CIAPIN1,METTL16,GART,SUV39H2,TRMT13,TRMU,ALKBH8,METTL8,HIST2H3D,CTR9,ETF1,FBL,TRMT10A,PRMT5,KMT2A,COQ3,PRMT3,FTSJ3,CARM1,GATAD2B,METTL1,KMT2D,SETD1B,WDR61,RNMT,BAZ2A,ALDH1L2,EHMT1,SETD2,METTL2A,WBSCR22,METTL23,PCMT1,METTL15,PRDM1,HIST1H4J,SETD7,KMT2C,MEN1,METTL22,MTR,MAT2A,DOT1L,NSD1,EHMT2,TRMT5,METTL6,PEMT,CAMKMT,FTSJ1,TRMT2A,TRMT10B,NDUFAF5,SETD6,SMYD3,METTL2B,GCSH |
| 1.655e-04 | -8.71 | FOSTER_KDM1A_TARGETS_DN | MSigDB lists | FOSTER_KDM1A_TARGETS_DN | 198 | 44 | 17758 | 2279 |
CUL7,EIF3C,CELSR3,RARS2,MRPL10,VPS45,PLOD1,SLC25A44,AP1B1,RAC3,GFM2,KDM1A,AMPD3,SUB1,ANKRD13A,SHC1,LDOC1L,NISCH,CORO1A,CPSF3L,NT5E,SAP30,IL11RA,KRT7,RNMT,SFSWAP,ANKMY2,POU2F1,COTL1,UBE2E1,TMEM186,WARS,TBC1D2,CCDC28B,MTHFD2,KDM4B,DCXR,LRRC40,RIOK3,BDH2,DIRAS1,ITGB4,DDIT3,TMEM141 |
| 1.662e-04 | -8.70 | SMAD3 (SMAD family member 3) | protein interactions | 4088 | 359 | 76 | 16036 | 2270 |
TCF12,USP7,SMARCA4,ZNF83,GIT2,RIOK2,SKI,PHC2,KDM2A,SREBF2,KANSL1,UCHL5,ANAPC10,ZEB1,RNF111,CORO1A,KDM5C,ZMYM2,SF3A1,ZCCHC14,PPARG,CDK4,NFIA,VIM,BRCA1,NUP214,YTHDF2,SMAD3,ZC3H12A,VDR,DDX3X,SKIL,EIF4ENIF1,BRCA2,CDC16,SMARCC1,E2F4,HIPK2,RUNX1,PARD3,LRCH1,USP15,HMGA2,FOXO1,SMAD7,GTF2IRD1,SLC25A12,OPA1,TGFBR2,FOXO3,NEDD4,SNW1,MYC,CFDP1,TANK,MED24,PCK2,PABPC1,KDM6B,SIK3,PSPC1,PRDM16,SETD2,ARID1A,MEN1,RPA1,IRS1,TRIB3,CLASRP,HIF1A,LEMD3,CDK9,MED15,ITGB4,PRKAR2A,XPO6 |
| 1.674e-04 | -8.69 | pancreas-carcinoma-acinar_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-acinar_carcinoma | 2069 | 318 | 17775 | 2278 |
ZNF292,WDR74,DCP1B,TNFRSF21,MKS1,CACNA1H,ENAH,SLC6A8,NUP160,SYNJ1,UBR5,MGA,SKI,PDZD2,ZFHX3,AP1M1,RNF111,ME1,KDM5C,CDK6,TBC1D8,NRAS,OSBP2,SETD1B,NR6A1,NOL8,C11orf80,AKAP12,EFHC1,DENND4A,SON,DDX60,ZNF197,DOT1L,BRCA2,NSMCE1,SEMA3C,DNAH2,WDR66,P2RY11,PRPF38B,EP400,IFT57,CELSR1,TRIO,PID1,RSF1,PDCD7,PITPNM1,CHN1,TECTA,DHX37,SCAF1,ASAP1,COPS3,MAP3K12,AGL,FMNL2,ANGPT2,FADS1,IFRD1,MYO10,PCCA,IDH3G,ARID1A,SLC26A11,ABCF1,DAGLA,DYNC1H1,ASCC3,VPS13C,EHMT2,VCAN,KIAA0196,NCOR1,PDLIM5,SMYD3,MAP2K4,COG5,AMOTL1,RAB11FIP4,DNM3,TRPM2,BIRC6,HFM1,MYH9,PTPRG,EEA1,TRIM66,ZNF827,CD96,ABCA12,FMNL1,WAC,NBEA,KMT2A,CDK12,CASP8AP2,LYST,KMT2D,FAM111B,PI4KAP2,SLCO6A1,PCNXL2,MEF2D,KCNH3,ELP2,SMARCC1,ZNF236,PAM,LARGE,IFT140,LAMA5,TMEM141,TRIM36,SERINC5,ZNF786,SSH2,NCOR2,BRAF,TMEM212,TTC27,B4GALT5,SF3A3,WDR37,RNASEH2B,IKBKAP,GDPD5,FOXO3,FAM8A1,UNC13A,NISCH,PMPCA,LTN1,NT5M,PLEKHG4,NAV3,FZD3,TMEM126A,ADSL,CASC1,NOP58,DDX49,SLC23A2,ETFDH,SRCAP,PXDN,ZDHHC11,DDX50,IREB2,HERC1,ATM,SLCO5A1,PTPN4,MYOM2,SORCS2,DOCK6,CUL7,TRIM16,MFGE8,FANCD2,PLOD1,RNF43,TMEM132A,SCAF8,MAP2K3,FRRS1,ABL2,ZNF804A,THADA,LONRF2,JAZF1,HYAL1,KIAA0922,CEP128,VPS13B,TIMM50,FLNC,TNK2,SESN2,TRIM13,ZNF124,CMIP,SKIV2L2,ANK2,LVRN,ARRDC3,KSR2,BRCA1,LAMA2,KMT2C,BSN,PEX1,TMEM132B,UBTF,HLCS,TP53BP1,CHD3,EEFSEC,RLTPR,CSMD3,DCAF5,FN1,RHOBTB1,SEC24D,ZCCHC8,TAF1,MAPK8IP3,EVPL,PHGDH,ETFB,DOPEY1,RNFT2,ABCA5,CEP290,SAMD11,ISPD,WNT16,CWF19L2,NT5E,CAMKK2,LAMC1,PPAT,OBSCN,LIG4,WWC1,EIF2A,TRAPPC6B,CORIN,METTL22,HERPUD1,DNAH14,EXOC6,NAP1L5,ATXN7,MYBBP1A,PALB2,FAT1,TBL1X,TBCK,PDSS2,TCF12,PCNT,CELSR3,MMRN2,PSTPIP2,LPCAT2,COBLL1,DENND3,PIBF1,PLXNB1,ZNF608,BRE,NVL,PPFIBP1,ARMC5,SLC38A2,MET,ZNF460,C6orf89,HN1,TLCD1,PCGF3,COL5A2,AKAP8L,FAM172A,KIRREL2,NHSL1,UBR4,TMEM186,BTBD11,RANBP2,ADNP,SIX5,CLEC16A,ZNF333,SCARB1,HEATR1,PUS1,BRD9,SMG1,MAP3K13,SUPT6H,RFX1,LETMD1,MAP1S,WDR26,ATF7IP,SOGA1,POGZ,PIP4K2A,SFI1,PRKCH,GART,SACS,TANK,TMEM99,DDX31,CD44,PCK2,AMOT,MICAL3,TOP1,DHX34,FERMT2,PDE2A,LENG8,EIF5B,ZNF407,TARS,CACNB1,CDH24,L3MBTL3,VPS37B,MSH3,MBD6,RWDD2B,NIT1 |
| 1.674e-04 | -8.69 | acinar_carcinoma | COSMIC cancer mutations | acinar_carcinoma | 2069 | 318 | 17775 | 2278 |
ZNF292,WDR74,DCP1B,TNFRSF21,MKS1,CACNA1H,ENAH,SLC6A8,NUP160,SYNJ1,UBR5,MGA,SKI,PDZD2,ZFHX3,AP1M1,RNF111,ME1,KDM5C,CDK6,TBC1D8,NRAS,OSBP2,SETD1B,NR6A1,NOL8,C11orf80,AKAP12,EFHC1,DENND4A,SON,DDX60,ZNF197,DOT1L,BRCA2,NSMCE1,SEMA3C,DNAH2,WDR66,P2RY11,PRPF38B,EP400,IFT57,CELSR1,TRIO,PID1,RSF1,PDCD7,PITPNM1,CHN1,TECTA,DHX37,SCAF1,ASAP1,COPS3,MAP3K12,AGL,FMNL2,ANGPT2,FADS1,IFRD1,MYO10,PCCA,IDH3G,ARID1A,SLC26A11,ABCF1,DAGLA,DYNC1H1,ASCC3,VPS13C,EHMT2,VCAN,KIAA0196,NCOR1,PDLIM5,SMYD3,MAP2K4,COG5,AMOTL1,RAB11FIP4,DNM3,TRPM2,BIRC6,HFM1,MYH9,PTPRG,EEA1,TRIM66,ZNF827,CD96,ABCA12,FMNL1,WAC,NBEA,KMT2A,CDK12,CASP8AP2,LYST,KMT2D,FAM111B,PI4KAP2,SLCO6A1,PCNXL2,MEF2D,KCNH3,ELP2,SMARCC1,ZNF236,PAM,LARGE,IFT140,LAMA5,TMEM141,TRIM36,SERINC5,ZNF786,SSH2,NCOR2,BRAF,TMEM212,TTC27,B4GALT5,SF3A3,WDR37,RNASEH2B,IKBKAP,GDPD5,FOXO3,FAM8A1,UNC13A,NISCH,PMPCA,LTN1,NT5M,PLEKHG4,NAV3,FZD3,TMEM126A,ADSL,CASC1,NOP58,DDX49,SLC23A2,ETFDH,SRCAP,PXDN,ZDHHC11,DDX50,IREB2,HERC1,ATM,SLCO5A1,PTPN4,MYOM2,SORCS2,DOCK6,CUL7,TRIM16,MFGE8,FANCD2,PLOD1,RNF43,TMEM132A,SCAF8,MAP2K3,FRRS1,ABL2,ZNF804A,THADA,LONRF2,JAZF1,HYAL1,KIAA0922,CEP128,VPS13B,TIMM50,FLNC,TNK2,SESN2,TRIM13,ZNF124,CMIP,SKIV2L2,ANK2,LVRN,ARRDC3,KSR2,BRCA1,LAMA2,KMT2C,BSN,PEX1,TMEM132B,UBTF,HLCS,TP53BP1,CHD3,EEFSEC,RLTPR,CSMD3,DCAF5,FN1,RHOBTB1,SEC24D,ZCCHC8,TAF1,MAPK8IP3,EVPL,PHGDH,ETFB,DOPEY1,RNFT2,ABCA5,CEP290,SAMD11,ISPD,WNT16,CWF19L2,NT5E,CAMKK2,LAMC1,PPAT,OBSCN,LIG4,WWC1,EIF2A,TRAPPC6B,CORIN,METTL22,HERPUD1,DNAH14,EXOC6,NAP1L5,ATXN7,MYBBP1A,PALB2,FAT1,TBL1X,TBCK,PDSS2,TCF12,PCNT,CELSR3,MMRN2,PSTPIP2,LPCAT2,COBLL1,DENND3,PIBF1,PLXNB1,ZNF608,BRE,NVL,PPFIBP1,ARMC5,SLC38A2,MET,ZNF460,C6orf89,HN1,TLCD1,PCGF3,COL5A2,AKAP8L,FAM172A,KIRREL2,NHSL1,UBR4,TMEM186,BTBD11,RANBP2,ADNP,SIX5,CLEC16A,ZNF333,SCARB1,HEATR1,PUS1,BRD9,SMG1,MAP3K13,SUPT6H,RFX1,LETMD1,MAP1S,WDR26,ATF7IP,SOGA1,POGZ,PIP4K2A,SFI1,PRKCH,GART,SACS,TANK,TMEM99,DDX31,CD44,PCK2,AMOT,MICAL3,TOP1,DHX34,FERMT2,PDE2A,LENG8,EIF5B,ZNF407,TARS,CACNB1,CDH24,L3MBTL3,VPS37B,MSH3,MBD6,RWDD2B,NIT1 |
| 1.678e-04 | -8.69 | organelle envelope | cellular component | GO:0031967 | 1059 | 174 | 17570 | 2233 |
IMMP2L,CYP24A1,LETM1,DDX19A,MRPL10,PLRG1,CERS5,TMEM109,SLC25A21,RNF43,PRKCA,NUP160,COA1,COX10,LPIN1,CIAPIN1,NOS1AP,AMBRA1,MRPS30,DST,PMAIP1,ATP5G2,LETM2,MAD1L1,RAN,NDUFA6,SLC25A23,SEH1L,MPST,TIMM50,TMPO,GDAP1,TXLNG,CDK4,MCL1,SHISA5,COTL1,KCNH2,FOXRED1,FLVCR1,MPC1,MGST1,STOML2,TIMM44,DDX3X,DNAJC1,MPV17,FIS1,CLU,UQCC2,SLC25A26,MTCH1,HERC2,AK2,PIK3R4,HSD17B10,XPO7,TIMM10,CMTM3,NDUFS7,PI4KB,TNPO3,GTF3C3,ALDH18A1,MRPL21,COQ3,TOMM34,NIPSNAP1,TIMM8B,RANBP6,BDNF,SIGMAR1,RB1CC1,POLA1,RAP1GAP2,BCS1L,PLCB1,CPT1A,CYB5B,ABCF1,C19orf70,CAT,KPNA1,TRAP1,LEMD3,SURF1,HK2,DHCR7,CPT1C,NDUFA5,SUCLG1,PAFAH1B1,NDUFAF2,PDK4,NDUFB5,NUP43,SLC9B2,SLC25A44,MIEF1,NDUFB3,TERF2IP,ABCA12,NUP133,MRPS27,RMDN3,ADCK4,MTHFD2L,TMEM120B,TMEM14C,IPO11,HTRA2,HN1,ACSL5,SFXN4,CPOX,NLN,TOR1AIP2,NUP214,SNCA,ATP5D,TAMM41,SMAD3,RANBP2,KPNA3,PEMT,TIMM17A,SLC25A11,RPS6KB1,FAHD1,CEP170,TMEM33,DNAJC2,SLC25A12,LETMD1,CHCHD10,RTN4,OPA1,POM121,SLC25A20,MRPS11,ABL1,NDUFV1,ANXA7,TRIAP1,PMPCA,PRICKLE2,PTGS1,SHMT2,SLC25A1,NAV3,WDFY3,TMEM126B,TMEM126A,ABCF2,MRPS10,RANGAP1,EXOG,RHOT2,GUF1,CHCHD6,MRPL36,ANXA1,MFN2,RETSAT,ETFDH,COQ9,SLC25A19,AEN,NDUFAF5,NDUFS5,GPAM,PGAM5,UQCC1,IPO4 |
| 1.693e-04 | -8.68 | DNA-directed RNA polymerase activity | molecular function | GO:0003899 | 42 | 15 | 16491 | 2164 |
POLR3D,PRIM2,POLA1,POLR1A,POLR3E,CRCP,MED20,POLR3B,POLR1B,POLR1C,ZNRD1,POLR1E,POLR2A,POLR3A,POLR3G |
| 1.695e-04 | -8.68 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1210 | 197 | 17775 | 2278 |
ARHGAP26,ASCC1,NF1,ATRX,TRPM6,CSNK2A1,BCOR,STK33,PRKCA,MGA,MAP2K3,PCDH7,SMARCB1,ZNF804A,ABL2,SRSF2,SREBF2,NEK6,DHX33,ZFYVE28,JAZF1,ZNF148,KDM5C,SRRM2,CDK6,PRKACB,SRPK2,SF3A1,TNK2,NRAS,SKAP2,CDK4,MED27,NFIA,CUX1,KSR2,SGK2,KMT2C,DOT1L,DYRK1B,TRRAP,SUFU,CSMD3,RIOK1,RUNX1,NRP1,SLC25A26,FN1,TAF1,CLK1,TRIO,NHS,PIK3R4,PID1,RLF,TGFBR2,SH2B3,PRKCE,SLC7A11,ABCA5,MYC,GMDS,NRIP1,LRSAM1,MAP3K12,SNX29,SIK3,IFRD1,CAMKK2,COL17A1,STAG1,KCNQ3,ARID5B,ZNF512B,OBSCN,MBNL2,AGAP1,USP46,ARIH2,PHF6,DYNC1H1,PRPF40B,GRIK4,LRP1B,ATAD5,RIOK3,PTP4A2,DDX10,TBCK,SH3PXD2A,MAP2K4,ZFHX2,DMXL2,RTTN,DDX18,ARID2,PDK4,KIAA0232,DDR2,RIPK1,SPATS2L,PTPRG,TNKS1BP1,EEA1,SEMA6A,DDX60L,PDE3A,RIOK2,CHD7,PRKD3,ABCA12,SOCS1,ZKSCAN1,RPS6KL1,IKBKB,TTC3,ADCK4,CEP63,MET,KMT2A,CDK12,KMT2D,BRD4,PDK1,PTBP2,STK10,UBR4,FGFR1,BTBD11,CAMK2D,RANBP2,SLC30A3,ASTN2,CLEC16A,HIPK2,WDR7,TSSC1,RPS6KB1,FUS,HEATR1,BRCC3,MID1,SMG1,PARD3,LRCH1,HMGA2,TNIK,BCKDK,BRAF,DNAJA4,MAP3K13,CAMK1,PDE4B,CLSTN2,MON2,MLH1,GDPD5,CSNK1A1,FOXP1,PSMF1,ABL1,PRKCH,ATXN7L1,RDX,DMRT1,SOX6,CLK2,RPS6KB2,TOP1,DIS3L2,KDM6B,ARNTL2,TTLL5,CLYBL,KDM5A,TEAD1,TEX14,PALLD,ZNF407,ARMC3,OXSR1,SRCAP,NSD1,TRIB3,ZDHHC11,NOL10,HELZ,POLE2,HERC1,ATM,SORCS2,RPS6KC1,ADK,RABEP1,ZAK,SLC16A10,STK4 |
| 1.695e-04 | -8.68 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1210 | 197 | 17775 | 2278 |
ARHGAP26,ASCC1,NF1,ATRX,TRPM6,CSNK2A1,BCOR,STK33,PRKCA,MGA,MAP2K3,PCDH7,SMARCB1,ZNF804A,ABL2,SRSF2,SREBF2,NEK6,DHX33,ZFYVE28,JAZF1,ZNF148,KDM5C,SRRM2,CDK6,PRKACB,SRPK2,SF3A1,TNK2,NRAS,SKAP2,CDK4,MED27,NFIA,CUX1,KSR2,SGK2,KMT2C,DOT1L,DYRK1B,TRRAP,SUFU,CSMD3,RIOK1,RUNX1,NRP1,SLC25A26,FN1,TAF1,CLK1,TRIO,NHS,PIK3R4,PID1,RLF,TGFBR2,SH2B3,PRKCE,SLC7A11,ABCA5,MYC,GMDS,NRIP1,LRSAM1,MAP3K12,SNX29,SIK3,IFRD1,CAMKK2,COL17A1,STAG1,KCNQ3,ARID5B,ZNF512B,OBSCN,MBNL2,AGAP1,USP46,ARIH2,PHF6,DYNC1H1,PRPF40B,GRIK4,LRP1B,ATAD5,RIOK3,PTP4A2,DDX10,TBCK,SH3PXD2A,MAP2K4,ZFHX2,DMXL2,RTTN,DDX18,ARID2,PDK4,KIAA0232,DDR2,RIPK1,SPATS2L,PTPRG,TNKS1BP1,EEA1,SEMA6A,DDX60L,PDE3A,RIOK2,CHD7,PRKD3,ABCA12,SOCS1,ZKSCAN1,RPS6KL1,IKBKB,TTC3,ADCK4,CEP63,MET,KMT2A,CDK12,KMT2D,BRD4,PDK1,PTBP2,STK10,UBR4,FGFR1,BTBD11,CAMK2D,RANBP2,SLC30A3,ASTN2,CLEC16A,HIPK2,WDR7,TSSC1,RPS6KB1,FUS,HEATR1,BRCC3,MID1,SMG1,PARD3,LRCH1,HMGA2,TNIK,BCKDK,BRAF,DNAJA4,MAP3K13,CAMK1,PDE4B,CLSTN2,MON2,MLH1,GDPD5,CSNK1A1,FOXP1,PSMF1,ABL1,PRKCH,ATXN7L1,RDX,DMRT1,SOX6,CLK2,RPS6KB2,TOP1,DIS3L2,KDM6B,ARNTL2,TTLL5,CLYBL,KDM5A,TEAD1,TEX14,PALLD,ZNF407,ARMC3,OXSR1,SRCAP,NSD1,TRIB3,ZDHHC11,NOL10,HELZ,POLE2,HERC1,ATM,SORCS2,RPS6KC1,ADK,RABEP1,ZAK,SLC16A10,STK4 |
| 1.697e-04 | -8.68 | pyrophosphatase activity | molecular function | GO:0016462 | 806 | 141 | 16491 | 2164 |
CGN,GNB3,ATRX,KIF5A,DDX19A,TUBE1,HLTF,RAC3,RAP1A,LONRF2,DHX33,XRCC2,MYH3,CHD2,RAN,LONP1,CHD9,ABCC4,SKIV2L2,ITPA,KATNAL1,GNL3,HSPA5,KIF15,ABCC2,MCM2,DDX60,LSG1,KIF16B,PEX1,GNAI1,RHOU,DDX3X,RAD18,CHD3,EEFSEC,RAD51B,ABCC3,DNAH2,DIRAS1,CLU,EP400,MCM6,AK6,RSF1,CHD5,DNAH1,ABCA7,DDX56,ENTPD5,DHX37,ABCA5,MCM5,GTF2H1,PPA1,ATP6V0D1,DDX28,GTF2H3,MYO10,EIF4A2,RAP1B,ABCF1,DNAH14,ATP9B,DYNC1H1,ASCC3,NSF,DNAH17,RRAGA,GPN1,DDX10,DNM3,ABCA3,TRPM2,DDX18,ATP6V1A,HFM1,MYO7A,OLA1,SMARCA4,MYH9,TUBB6,MCM9,DDX60L,DHX35,HSPA1A,CHD7,ABCA12,MYH15,MSH4,FHIT,GNG5,ATP6AP1L,SKIV2L,PMS1,RFC4,RFC3,DDX41,TUBA1A,RAB7A,MTIF2,ATP6V0A1,GNL1,ATP8B2,NUDT15,RAB10,DHX57,RAD54B,ATP5D,MDN1,SEPT5,RAB30,VWA8,C10orf2,KLC4,KIF5C,ATF7IP,MLH1,OPA1,GFM2,DCTPP1,DDX31,DYNC2H1,TOP1,DDX24,SMARCAD1,ABCF2,DHX34,EIF5B,GUF1,RHOT2,DDX49,MFN2,HSPA1B,ANXA1,ZRANB3,SRCAP,DDX50,HELZ,MSH3,KIF1B |
| 1.711e-04 | -8.67 | RFC4 (replication factor C subunit 4) | protein interactions | 5984 | 70 | 22 | 16036 | 2270 |
PRAME,PMS1,RFC3,BRD4,FN1,SMARCAD1,CDK4,FAN1,BRCA1,ABCF1,FKBP3,RPA1,IGF2BP3,EPRS,ATAD5,CDK9,MYC,USP20,RNF2,EIF2B3,YBX3,HNRNPM |
| 1.723e-04 | -8.67 | serine family amino acid metabolic process | biological process | GO:0009069 | 38 | 14 | 16441 | 2138 |
SEPHS2,GGT1,DMGDH,SDSL,GART,PSAT1,MRI1,SHMT2,AHCYL1,PHGDH,AHCYL2,MPST,GCSH,MTHFD1 |
| 1.731e-04 | -8.66 | KLK15 (kallikrein related peptidase 15) | protein interactions | 55554 | 8 | 6 | 16036 | 2270 |
SMG7,CBWD1,TRIP6,SEC16A,ABHD3,SLC25A20 |
| 1.732e-04 | -8.66 | V$MYCMAX_01 | MSigDB lists | V$MYCMAX_01 | 240 | 51 | 17758 | 2279 |
PPARGC1B,DYM,ATF7IP,TGFB2,TIMM10,RPS6KA5,FOXO3,UBR5,IQGAP2,NOP56,DCTPP1,CAD,ARMC6,SUCLG2,IGF2BP1,ETV1,PRPS1,PABPC1,SERBP1,NUDC,TOP1,MTHFD1,RTN4RL2,PPP1R9B,NRAS,SIGMAR1,NR6A1,MON1A,PPAT,KIAA0586,SATB2,KRTCAP2,ODC1,NOP58,UBR4,MAT2A,CTIF,SYNCRIP,HNRNPH3,PER1,HSPBAP1,BCAS3,HOXA3,CTAGE5,TRMT2A,PUS1,BMP4,YEATS2,GCSH,SLC43A1,USP15 |
| 1.732e-04 | -8.66 | V$CREB_02 | MSigDB lists | V$CREB_02 | 240 | 51 | 17758 | 2279 |
POLB,SPRED2,CYLD,BRAF,ID1,SEC24D,NF1,MAP3K13,PAFAH1B1,RPS29,PPP2R2A,RCAN1,CORO6,PELP1,RING1,PRKCH,RNF40,BRE,SREBF2,THADA,GLYR1,PRICKLE2,GTF2H1,CHD2,FBXL19,SNAPC5,DDX28,VPS37A,SMARCAD1,MED27,ZC3H18,SCFD2,SULT4A1,MRRF,GNL1,SNAP25,DLST,MBNL2,ERC1,USP36,CAMK2D,NOL10,SPAG9,RBBP8,GTF2A1,VPS37B,XPNPEP1,UMPS,MDN1,MAGI1,NAPA |
| 1.733e-04 | -8.66 | V$TGIF_01 | MSigDB lists | V$TGIF_01 | 234 | 50 | 17758 | 2279 |
ASH1L,DNM3,CYLD,MAP2K5,MAP3K13,C16orf52,HFM1,TMEM109,CLSTN2,SLC25A12,LPCAT3,ST7L,TNKS1BP1,FOXO3,UBR5,NEDD4,DDIT4,DOPEY1,FAM192A,RSPRY1,ABL2,ANKRD13A,IKZF5,METTL8,HCFC2,C15orf41,C12orf4,DPF3,AEBP2,GPHN,ZC3H18,WWC1,OBSCN,R3HDM2,IMPDH2,SOX4,KCNH2,ONECUT2,DENND4A,FKBP3,SLC23A2,WARS,IRS1,HIF1A,GREB1L,TRAF3,RPS6KB1,FNBP1L,SPOCK2,USP15 |
| 1.733e-04 | -8.66 | PRMT5 (protein arginine methyltransferase 5) | protein interactions | 10419 | 144 | 37 | 16036 | 2270 |
CUL7,CUL4A,FN1,CLK1,RBFOX2,TCF3,SIRT7,OLA1,SF3A3,SMARCA4,ARID1B,SMARCB1,SKI,DST,CTNNBL1,SHC1,COPS4,MCM5,MBD2,FBL,PRMT5,TERF2,SIRT6,CDK4,GRHL3,PRDM1,MEF2D,LENG8,SUPT5H,CLNS1A,DYNC1H1,TRIB3,SMARCC1,ZNF436,EIF2S1,RIOK1,AGO3 |
| 1.751e-04 | -8.65 | nucleotide catabolic process | biological process | GO:0009166 | 61 | 19 | 16441 | 2138 |
PDE4A,ITPA,UPP1,PDE4B,PDE2A,NUDT15,PDE3B,PDE3A,PDE8B,CAT,AMPD3,HPRT1,PDE10A,NT5C,NT5M,OGG1,PDE9A,MUTYH,NT5E |
| 1.752e-04 | -8.65 | PDGF_UP.V1_UP | MSigDB lists | PDGF_UP.V1_UP | 141 | 34 | 17758 | 2279 |
MPI,EGR1,URB2,TFIP11,NUP160,ETFB,FDX1,MRPS11,DDIT4,ANXA7,ATXN2,SLC39A7,ACOT11,NDRG4,JOSD1,CLDND1,ZNF460,CDK6,FAM98A,RANBP6,NRAS,GNL1,STK10,PAF1,ATXN7,GADD45A,SERINC1,ADAM9,PPP1R12B,ARC,TAF12,TMEM158,MORC2,ZBTB24 |
| 1.756e-04 | -8.65 | KRR1 (KRR1, small subunit (SSU) processome component, homolog (yeast)) | protein interactions | 11103 | 61 | 20 | 16036 | 2270 |
WDR36,NIFK,LIN28B,DDX24,DDX18,USP49,GNL3,SIRT7,UTP15,GNL1,ZNF346,DKC1,NOP58,PUM3,NOP56,PES1,DDX56,ZNF622,RNF2,BMI1 |
| 1.760e-04 | -8.65 | ILF2 (interleukin enhancer binding factor 2) | protein interactions | 3608 | 263 | 59 | 16036 | 2270 |
MIF4GD,MCM6,CUL7,JUP,FN1,DDX18,SIRT7,LAGE3,LAMTOR3,SSR4,BIRC2,HSPA1A,PABPC4,NOP56,IGF2BP3,RPS16,PTRF,NVL,PPID,MCM5,GLYR1,SHMT2,DDX31,ALDH18A1,MRPL21,YBX3,SRRM2,FTSJ3,SPTAN1,DDX28,RFC4,HSPA5,TPM4,RAP1B,CCNDBP1,MCM2,SUPT5H,SON,RBM28,ABCF1,MTR,FKBP3,PUM3,RPA1,TBC1D2,RANBP2,MYBBP1A,SYNCRIP,HNRNPR,CDK9,SNAP23,COPS5,CEBPZ,CUL2,H2AFX,SGSM2,EIF2B3,TXN2,BMI1 |
| 1.760e-04 | -8.64 | cation binding | molecular function | GO:0043169 | 4106 | 607 | 16491 | 2164 |
ADAM19,AARS2,CACNA1H,HLTF,NT5C3A,ZNF44,HMOX2,CIAPIN1,PCDH7,SKI,ZNF37A,MMP7,NEK6,ZFHX3,IKZF5,THAP4,WIZ,ZNF148,KDM5C,HRG,ZNRD1,FXN,PPM1K,LIMA1,EHMT1,MSRB3,PLEKHM3,MCM2,ZNF197,ZNF266,RBSN,SUPT4H1,RAD18,RIOK1,RUNX1,ZNF532,LPP,CARS,ADGRE2,HERC2,TNNC1,TRIP6,SIRT7,PLA2G12A,RSF1,PARN,PITPNM1,YARS2,RSPRY1,CHN1,RBM20,UBE3A,EIF2S2,APLF,ALKBH8,ZNF326,CALN1,ZNF518B,PPA1,ANGPT2,ZNF675,GATAD2B,GTF2H3,TIMM8B,ZNF587,PRDM16,EPS15L1,IDH3G,TYW1,ZNF512B,RYR2,IMPDH2,MBNL2,TRIM37,ZNF655,LRP1B,NME7,PDLIM1,EHMT2,ZNF160,ADGRE5,CNOT6,BPNT1,PDLIM5,RAB11FIP4,MAP2K5,ZNF516,TRERF1,GTF2H2C,NPAS2,AGAP6,ZMAT2,EEA1,ZBED2,PRKD3,ZSWIM7,ERI1,ZKSCAN1,MMP14,INTS12,NT5C,PEG10,ZC3H3,KMT2D,STAMBP,ZNF480,ADAM32,NUDT15,MAT2A,PDE8B,TAF2,FBXL5,ZFAND3,KDM4B,NSMCE2,PAM,FUS,BRCC3,ZBTB11,MORC2,TRIM36,ZNF786,SESTD1,SF3A3,JMJD6,GAS6,TRIM22,ZNF691,MBNL1,SUV39H2,TAF3,ACAP3,UNC13A,ANXA5,LTN1,PTGS1,ZNF710,FBXL19,DIS3L2,SPTAN1,DDHD1,CLYBL,POLK,ZC4H2,ZC3H18,ZNF467,PDE3B,ANXA1,RPA1,OXSR1,TOE1,ETFDH,NSD1,RARS,BAZ2B,PXDN,KDM4C,CYP24A1,TRIM16,POLR1A,RNF43,BIRC2,GIT2,FRRS1,ABL2,AMPD3,HKR1,ZNF85,ZNF3,ZMYM2,SLC25A23,DSC3,RBCK1,SLC3A2,ZNF124,AEBP2,PPARG,BAZ2A,ZNF414,ATOX1,HSPA5,GDPD1,BRCA1,ZNF91,MLLT10,BSN,HPRT1,ZNF622,CHD3,ADAM9,PPP3CC,RNF214,C2CD5,TTN,AOC3,PRSS3,NKD2,MEX3A,SMAD7,FAN1,ZFP36L1,TRIM15,ZIC2,RLF,RNF40,RNFT2,ZNF358,TRMT13,PDE10A,LRSAM1,NT5E,CAMKK2,USP49,OBSCN,MEX3B,ZNFX1,CYB5B,NR2F1,ZNF430,DTD1,BRSK2,TESC,RNF114,MPI,CYLD,PAPD4,ARID2,LPCAT2,RPS29,GPR143,ZNF83,RNF24,ZNF709,ZNF121,RPAIN,FDX1,CAD,ZNF608,ZBTB21,IDI1,JAG1,UBR1,ZDHHC6,CYB5D1,ZFP37,RNF2,PRMT3,SOBP,SEC24A,KAT8,KDM3B,PCGF3,AKAP8L,DDX41,AKAP13,CA5B,ZNF251,EXO1,SMAD3,RANBP2,ZNF333,KLF4,ITGA2,ZNF436,ZNF18,FAHD1,MUTYH,ZNF589,ZNF507,ESCO1,MCM10,MAP3K13,AGO2,APRT,ZNF346,FOXP1,POGZ,ZNF594,ADH5,NDUFV1,ANXA7,ZNF561,PRICKLE2,POLR1B,PCK2,ADAMTSL3,ZNF654,ZMYM5,TPM4,TOP3A,EXOG,RHOT2,POLR3A,ZRANB3,CDH24,DSC2,ZBTB8OS,ADAT2,FNTB,USP20,RBM26,ZNF32,NR2F2,ZNF292,POLB,MYCBP2,PRKCSH,ADAMTS6,GYG1,PRKCA,UBR5,AARS,S100A10,ZFYVE28,RNF111,ME1,CSGALNACT2,ZNF646,DPF3,NR6A1,EYA3,VSNL1,EFHC1,ZDHHC14,GNAI1,GZF1,SH3RF1,NSMCE1,ZNF81,HIC2,XPNPEP1,NRP1,CCNB1IP1,BMI1,SPOCK2,ZMAT3,SPOCK3,ZNF598,DROSHA,CELSR1,EGR1,ZHX3,TATDN3,CRACR2A,CCDC47,TGFBR2,CHD5,NDUFS7,ANXA10,PRKCE,HR,ZNF586,ASAP1,CNOT4,LPCAT1,PRPS1,SCAF11,ADARB1,SIK3,RREB1,PRIM2,PCCA,AOC2,POLA1,PLCB1,ZNF850,MTR,ARIH2,PHF6,ATP9B,ZNF425,DAGLA,CAT,MTHFD2,ALKBH3,NSF,ZZEF1,VCAN,ZBTB12,ZCCHC6,RIOK3,DPEP1,CNDP2,SMYD3,ZFHX2,ZNF254,SYT17,LIN28B,ZBTB37,UROD,OLA1,RING1,PDE3A,TRIM66,PHC2,NUBPL,ZNF827,KDM2A,TTC3,KMT2A,SAP30,ZCCHC14,MARCH6,DHX57,ZBTB25,SNCA,VDR,BAZ1A,DNAJA3,ZNF236,MBTD1,LARGE,ALKBH1,TRAF3,ANXA2,MID1,TROVE2,BRAF,B4GALT5,ZNF280C,NFX1,FARS2,SLC25A12,MYNN,LIAS,OPA1,NOL3,INPP1,RPS6KA5,ZNF239,ABL1,ZNF483,DCTPP1,PMPCA,S100A14,NT5M,MBTPS2,TSHZ1,PXN,APEX1,WDFY3,ZFYVE1,KCNMA1,APTX,KLF6,POLR2A,ZFP62,ZNF155,IREB2,ZDHHC11,HELZ,RNF138,ADK,STK4,KAT6A,ZNF76,PHF3,LETM1,KMT2E,NF1,ATRX,TRPM6,RCHY1,ZNF107,PLOD1,SIRT2,CUTC,DST,ZNF804A,LONRF2,JAZF1,ZNHIT6,ANAPC11,ZEB1,POLR3B,GALNT18,TRIM14,PRKACB,ELOF1,SRPK2,ZBTB17,TNK2,DTNB,DEAF1,TRIM13,ZNF195,ZNF680,ITPA,SIRT6,LVRN,VWCE,MINA,KSR2,HDAC8,ZSCAN2,KMT2C,CDHR3,RHOU,GATA6,ZGRF1,GALNT10,EME1,ZNF397,ZC3H8,NOCT,SEC24D,ZCCHC8,DPF2,C11orf54,TIMM10,RNF141,P3H1,ZNF354A,PRF1,ZCCHC7,ZNF629,ZNF234,HBG2,PDE4A,PPAT,ZBED4,ELP3,JMJD1C,TBXAS1,ZFP14,LIG4,PRDM1,AGAP1,SYT1,FAT1,FDPS,CDKAL1,ZFP90,PDE9A,ZBTB24,ZNF706,CHMP2A,DLL4,ASH1L,CELSR3,ARSJ,PUDP,ZC3H13,RIOK2,ZSCAN5A,VPS18,ZNF142,ITGAX,CPSF3,ZNF460,TMLHE,MCEE,ANTXR2,COL5A2,NLN,ATP8B2,EDEM2,UBR4,S100A16,ZC3H12A,IKZF4,DUS3L,ALAD,ADNP,ZNF557,COPS5,RNF130,SMG1,YDJC,DNAJA4,DBF4,PDE4B,TKFC,CLSTN2,MAN1A1,PRKCH,GART,SEC24C,TANK,DSG2,ERI3,DMRT1,MICAL3,KDM6B,MARCH9,GPHN,KDM5B,ZNF821,KDM5A,ANKMY2,ASAP3,ZNF324B,PDE2A,ZNF407,NAPEPLD,ZNF221,RERE,ZNF708,DAGLB,ZNF330,AGTPBP1,ZRANB2,TATDN1,MMP16,ZAK,ZSWIM6,HRH1 |
| 1.802e-04 | -8.62 | MEK_UP.V1_DN | MSigDB lists | MEK_UP.V1_DN | 187 | 42 | 17758 | 2279 |
TCF12,PRPF38B,IFT57,INSIG2,SEC24D,UTP14A,C16orf45,SMAD7,ZNF107,ID2,KIF5C,RNF43,CSTA,CHN1,ABCA12,IFIT5,CBR4,MYC,LTN1,GREB1,NRIP1,AGL,PRMT3,TRIM14,MYB,PMS1,GDAP1,PTBP2,SSFA2,MTIF2,ELOVL6,TFPI,JMJD1C,NOL8,RSBN1,SATB2,OASL,DDX60,ISG15,TAF2,BAZ2B,HSPB8 |
| 1.833e-04 | -8.60 | GCM_MLL | MSigDB lists | GCM_MLL | 164 | 38 | 17758 | 2279 |
ZNF292,ASCC1,EPM2AIP1,AARS2,SMAD7,FAN1,ATG2B,C1orf52,FOXO3,GFM2,POGZ,COMMD9,NUP133,CELF1,TTC17,PKNOX1,KDM3B,CHD9,BAZ2A,IDH3G,TRAPPC6B,DENND4A,VPS53,TAF9B,APBB3,SUFU,HNRNPR,INTS5,HNRNPH3,LUC7L3,LEMD3,CLEC16A,FNTB,ASB3,CNOT6,TBCK,BRD9,SMG1 |
| 1.833e-04 | -8.60 | MORF_PPP1CC | MSigDB lists | MORF_PPP1CC | 164 | 38 | 17758 | 2279 |
MYCBP2,MCM6,AK2,KHDRBS1,SF3A3,XPO7,POM121,PABPC4,HDDC2,NDUFV1,SREBF2,CBR4,MRPS27,TNPO3,SHMT2,SSBP1,YARS,GNG5,SERBP1,NUDC,IFRD1,RFC4,DEAF1,GARS,SKIV2L2,NPM3,R3HDM1,IMPDH2,MCM2,DKC1,TARS,CHAF1A,EPRS,CDC16,SMARCC1,HNRNPR,GPN1,TROVE2 |
| 1.837e-04 | -8.60 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN | 193 | 43 | 17758 | 2279 |
CARS,ID1,OLA1,TMEM109,TRAK1,CHCHD10,RNASEH2B,ETFB,DCTPP1,CAD,SUB1,NDUFV1,IDI1,MCM5,PDS5B,VCL,CARM1,ELOF1,FDFT1,RFC4,PRIM2,SKAP2,MINA,MARCKSL1,RNH1,BRCA1,MCM2,CYB5B,TRIM37,TAMM41,SYNGR2,FDPS,HK2,XPNPEP1,CRCP,NCBP2,ANXA2,NDUFS5,RBPJ,HMBS,DHCR7,BLMH,GCSH |
| 1.837e-04 | -8.60 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | 193 | 43 | 17758 | 2279 |
SLC12A7,MYCBP2,XPC,WDR74,ST6GAL1,SMAD7,MAP1S,SSBP2,FOXP1,BZW2,PIP4K2A,MFHAS1,DDIT4,SKI,RNF141,AMPD3,RABGAP1L,MYC,TTC3,CNOT4,PRMT3,TOMM34,SKIV2L,EVL,PDK1,WLS,POU2F1,IL6R,EVI5,MAT2A,RERE,FBXO21,IFT81,SRCAP,TSR1,GADD45A,ARID3B,STX1A,MSH3,FNTB,RPS6KC1,SETD6,IPO4 |
| 1.840e-04 | -8.60 | MODULE_219 | MSigDB lists | MODULE_219 | 26 | 11 | 17758 | 2279 |
HPRT1,GART,AK2,ITPA,ADSL,UMPS,APRT,CMPK1,IMPDH2,ADK,MTHFD1 |
| 1.842e-04 | -8.60 | ARID | prosite domains | PS51011 | 15 | 8 | 11866 | 1504 |
KDM5B,ARID2,ARID3B,KDM5A,ARID5B,KDM5C,ARID1A,ARID1B |
| 1.842e-04 | -8.60 | POST_SET | prosite domains | PS50868 | 15 | 8 | 11866 | 1504 |
NSD1,ASH1L,KMT2D,SETD1B,SUV39H2,SETD2,KMT2C,KMT2A |
| 1.847e-04 | -8.60 | Activation of gene expression by SREBF (SREBP) | REACTOME pathways | R-HSA-2426168 | 41 | 15 | 8202 | 1117 |
LSS,CHD9,IDI1,MVK,SREBF2,ELOVL6,FDPS,SMARCD3,SQLE,TBL1X,GPAM,DHCR7,CARM1,FDFT1,HMGCR |
| 1.848e-04 | -8.60 | TCTGGAC,MIR-198 | MSigDB lists | TCTGGAC,MIR-198 | 82 | 23 | 17758 | 2279 |
TSHZ1,PPP1R9B,NCOR2,CDCP1,TRNP1,ZNF821,LSM12,ABCF2,SLC2A1,MED13L,PBX1,LETMD1,SHISA5,ARID1A,POGZ,PHF6,RAD54B,BSN,TCF7L1,ADNP,GLYR1,MET,NRIP1 |
| 1.850e-04 | -8.60 | peptidyl-lysine methylation | biological process | GO:0018022 | 71 | 21 | 16441 | 2138 |
KMT2D,ASH1L,SETD1B,WDR61,BAZ2A,KMT2E,EHMT1,SETD2,SETD7,KMT2C,MEN1,CHD5,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,CTR9,SETD6,KMT2A,SMYD3 |
| 1.855e-04 | -8.59 | CIAO1 (cytosolic iron-sulfur assembly component 1) | protein interactions | 9391 | 75 | 23 | 16036 | 2270 |
CTU2,WDR75,FMNL3,PRIM2,WDR61,PPAT,POLA1,TYW1,ELP3,CCDC7,MAK16,CDC73,PAF1,TOE1,IREB2,ELP2,NSRP1,ELP5,MCM5,CDKAL1,CTR9,USP11,FMNL2 |
| 1.864e-04 | -8.59 | catalytic step 2 spliceosome | cellular component | GO:0071013 | 88 | 24 | 17570 | 2233 |
SART1,DDX41,SKIV2L2,ZCCHC8,TFIP11,PLRG1,SF3A3,PPIL1,PNN,DHX35,HNRNPA3,SNW1,SYNCRIP,BCAS2,PHF5A,HNRNPR,CWC27,GPATCH1,SRRM2,PPIL3,PABPC1,HNRNPM,PRPF19,SF3A1 |
| 1.902e-04 | -8.57 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular function | GO:0016818 | 808 | 141 | 16491 | 2164 |
CGN,GNB3,ATRX,KIF5A,DDX19A,TUBE1,HLTF,RAC3,RAP1A,LONRF2,DHX33,XRCC2,MYH3,CHD2,RAN,LONP1,CHD9,ABCC4,SKIV2L2,ITPA,KATNAL1,GNL3,HSPA5,KIF15,ABCC2,MCM2,DDX60,LSG1,PEX1,KIF16B,GNAI1,RHOU,DDX3X,RAD18,CHD3,EEFSEC,RAD51B,ABCC3,DNAH2,DIRAS1,CLU,EP400,MCM6,AK6,RSF1,CHD5,DNAH1,ABCA7,DDX56,ENTPD5,DHX37,ABCA5,MCM5,GTF2H1,PPA1,ATP6V0D1,DDX28,GTF2H3,MYO10,EIF4A2,RAP1B,ABCF1,DNAH14,ATP9B,DYNC1H1,ASCC3,NSF,DNAH17,RRAGA,GPN1,DDX10,DNM3,ABCA3,TRPM2,DDX18,ATP6V1A,HFM1,MYO7A,OLA1,SMARCA4,MYH9,TUBB6,MCM9,DDX60L,DHX35,HSPA1A,CHD7,ABCA12,MYH15,MSH4,FHIT,GNG5,ATP6AP1L,SKIV2L,PMS1,RFC4,RFC3,TUBA1A,DDX41,RAB7A,MTIF2,ATP6V0A1,GNL1,ATP8B2,NUDT15,RAB10,DHX57,RAD54B,ATP5D,MDN1,SEPT5,RAB30,VWA8,C10orf2,KLC4,KIF5C,ATF7IP,MLH1,OPA1,GFM2,DCTPP1,DDX31,DYNC2H1,TOP1,DDX24,SMARCAD1,ABCF2,DHX34,EIF5B,GUF1,RHOT2,DDX49,MFN2,HSPA1B,ANXA1,ZRANB3,SRCAP,DDX50,HELZ,MSH3,KIF1B |
| 1.920e-04 | -8.56 | WANG_CLIM2_TARGETS_UP | MSigDB lists | WANG_CLIM2_TARGETS_UP | 217 | 47 | 17758 | 2279 |
BANP,RBM33,ZHX3,ZCCHC8,TAF1,CA11,ARID2,KIF5A,GFM2,POGZ,PELP1,DDIT4,ATXN7L1,ARMC6,NISCH,PPIL2,PDS5B,ZNF148,MET,NRIP1,MTHFD2L,CAV2,SERBP1,MYB,TMPO,SKIV2L,C21orf58,TNK2,TTLL5,WDR61,SSFA2,GLTSCR2,AOC2,PSMC3IP,PTPN12,RANGAP1,SERP1,FGFR1,ARIH2,FSCN1,ASTN2,ZNF160,ABCC3,WDR33,MAGI1,NR2F2,GPATCH4 |
| 1.920e-04 | -8.56 | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | 217 | 47 | 17758 | 2279 |
CYP24A1,ZNF516,TRIP6,NPAS2,LPCAT2,C14orf159,SEMA6A,DST,ATXN7L1,ZNF827,JAG1,PI4KB,THAP4,CBR4,MYC,IKBKB,HIBCH,ARHGAP1,CD44,SAMD4A,NT5E,MYB,HMBOX1,CHD9,ATF4,TRNP1,PXN,ABCC4,THSD4,COL4A3BP,TMEM216,RFX2,ATXN1,BMS1,AKAP13,ZNF655,MLLT10,SMAD3,AHNAK,TTC38,ITGA2,WDR73,HEATR1,SH3PXD2A,IGBP1,TESC,ZSWIM6 |
| 1.949e-04 | -8.54 | negative regulation of biosynthetic process | biological process | GO:0009890 | 1481 | 238 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,PRKCA,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,GPR87,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,ATF4,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,BRCA2,SUPT4H1,EIF4ENIF1,INSIG1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,TNRC6A,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,PID1,BARX2,ZIC2,RSF1,CDC73,ABCA7,IGF2BP3,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,IGF2BP1,PRMT5,NRIP1,LPCAT1,TERF2,MYB,GATAD2B,ZNF675,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,EPRS,MYBBP1A,SYNCRIP,EHMT2,TRAP1,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,AGO3,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,MAP2K5,CYLD,RBFOX2,SMARCA4,PBX1,PIBF1,RING1,KDM1A,PAIP2,ZBTB21,ACD,PPID,DNAJB6,RNF2,CTC1,CASP8AP2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,ENC1,FGFR1,PDE8B,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,EIF2B3,SETD6,YEATS2,HMGA2,DNAJC2,NOSTRIN,NCOR2,INSIG2,TCF3,AGO2,H2AFJ,NFX1,ID2,ATF7IP,IGF2BP2,GAS6,TRIM22,SOGA1,BHLHE40,RPS6KA5,FOXP1,GIGYF2,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,CELF1,YBX3,ERRFI1,SAMD4A,DMRT1,SOX6,CLK2,FGF9,MSX1,KDM5B,APEX1,PSPC1,FOXN3,SCMH1,HIST1H4J,IL6R,PDE2A,MEN1,UBC,ZRANB3,RERE,MKX,DKK1,TRIB3,NSD1,IREB2,TBX3,SET,EIF2S1,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 1.976e-04 | -8.53 | GARS (glycyl-tRNA synthetase) | protein interactions | 2617 | 80 | 24 | 16036 | 2270 |
CARS,NARS,HARS,MARS,XPO7,AARS,TARS,CIAPIN1,TTC1,RARS,EPRS,ASNS,GTF2A1,FDPS,HIRIP3,XPNPEP1,HARS2,ME1,CD44,USP11,AGL,TROVE2,NMD3,SERBP1 |
| 1.981e-04 | -8.53 | ARID_dom | interpro domains | IPR001606 | 15 | 8 | 18293 | 2341 |
KDM5B,ARID2,ARID3B,KDM5A,ARID5B,KDM5C,ARID1A,ARID1B |
| 1.991e-04 | -8.52 | SMAD2 (SMAD family member 2) | protein interactions | 4087 | 281 | 62 | 16036 | 2270 |
TCF12,BTBD2,KHDRBS1,SMAD7,GTF2IRD1,SMARCA4,AP1B1,OPA1,FOXO3,UBR5,ARID1B,NEDD4,SKI,CAD,SNW1,UCHL5,ZNHIT6,MYC,ANAPC10,ZEB1,RNF111,MED24,ANP32B,RAN,KDM6B,GATAD2B,RANBP6,ANTXR2,SIK3,STAG1,PPARG,STAMBP,PRDM16,PSPC1,CDK4,NFIA,CAV1,BRCA1,ARID1A,SYT1,NUP214,SMAD3,DYNC1H1,BAZ1A,SKIL,BRCA2,CDC16,SMARCC1,CDK9,E2F4,LEMD3,HIPK2,COPS5,MED15,IRAK2,PSAP,RUNX1,ITGB4,LAMA5,PARD3,MEF2C,USP15 |
| 1.997e-04 | -8.52 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 182 | 41 | 17758 | 2279 |
VMA21,PTP4A1,EP400,C9orf78,POLR1A,SMAD7,NFX1,SLC25A44,SLC30A7,MTUS1,SH2B3,SACS,NOP16,SLC38A2,POLR3B,KIAA0922,NRIP1,MTHFD2L,HCFC2,CDK12,GNL3,ARID5B,WBSCR22,MAPK1IP1L,SLC35D1,EIF5B,ABCF1,TAF9B,ANXA1,SLC7A1,ARHGAP21,HIF1A,CEBPZ,WDR73,HIC2,CSRNP1,BBIP1,RNF130,PUS1,GPATCH4,TMEM33 |
| 2.007e-04 | -8.51 | adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_cortical_carcinoma | 2342 | 355 | 17775 | 2278 |
MYCBP2,CDCP1,CACNA1H,HLTF,NBEAL1,LRP5L,LPAR3,LPIN1,CIAPIN1,PABPC4,MGA,PCDH7,GIPR,PDZD2,SREBF2,IKZF5,PDS5B,VPS52,KDM5C,SRRM2,ZNF646,NRAS,PTPRM,EHMT1,KIF15,WDHD1,SEMA3F,ZDHHC14,DDX60,RBM28,SAP30BP,MAK16,PLCXD2,PYCR1,OSBPL1A,STOML2,AHNAK,TRRAP,LSM14A,CCNT1,SEMA3C,DNAH2,CCNB1IP1,WDR66,SPOCK3,PTPN14,HERC2,ANKRD17,ZHX3,ST6GAL1,SIRT7,TRIO,DPM3,PRPF39,TGFBR2,CDC73,ANXA10,MTUS1,RBM20,ENTPD5,KIAA1671,NOVA2,ALKBH8,MED24,MYB,SIK3,RREB1,MYO10,RDH10,RYR2,PTPN12,ARID1A,EVI5,USP46,ANGPTL4,ABCF1,NCDN,DYNC1H1,ZNF425,VPS13C,LRP1B,MTHFD2,KPNA1,KIDINS220,PDLIM1,EHMT2,TRAP1,PMEPA1,D2HGDH,ZCCHC6,PEX13,CNOT6,KIAA0196,MACROD1,DHCR7,ARHGAP10,ZFHX2,SYT17,DNM3,BIRC6,HFM1,MYH9,PTPRG,TRIM66,RPGRIP1L,PDE3A,TERF2IP,SLX4,ABCA12,GLYR1,LPIN2,MRPS27,C16orf58,NBEA,TTC3,KMT2A,CDK12,CASP8AP2,LYST,ZCCHC14,KMT2D,GON4L,ATP6V0A1,PCNXL2,GNL1,MARCH6,GSTCD,DSP,STK10,DCBLD2,GNG2,DNTTIP1,KDM4B,PAM,IFT140,TRAF3,LAMA5,BRAF,XPC,SESTD1,NFX1,FARS2,KIF5C,RTN4,AKT1S1,MON2,GDPD5,RSRC1,TMCO6,ZNF239,ZNF483,SUV39H2,CFDP1,LTN1,HARS2,LARP4B,FBXL19,DIS3L2,FAM120B,DDHD1,TSHZ1,C19orf43,OASL,PPIP5K2,ECH1,CCDC150,UBC,INF2,NSD1,SRCAP,RETSAT,ZNF155,HERC1,ATM,SLCO5A1,SVIL,PTPN4,MYOM2,MTMR1,CUL7,FEM1C,ATRX,NF1,GPBP1L1,KIF5A,POLR1A,PPARGC1B,PLOD1,RNF43,BCOR,FAM13A,TMEM132A,COX10,BIRC2,SNAPC4,FRRS1,DHX33,MARVELD2,ANAPC11,ANKRD11,MYH3,GPATCH1,HYAL1,RAN,NDUFA6,ZMYM2,FAM184A,DSC3,FMNL3,CHD9,SLC3A2,MIOS,ZNF195,ABCC4,BAZ2A,ANK2,GDPD1,VWCE,HDAC8,MTHFD1L,KMT2C,SERGEF,CHAF1A,TAF9B,KIF16B,TCF7L1,TRMT5,TP53BP1,CC2D1B,RLTPR,SGSM2,EME1,SEC24D,TAF1,ALG8,EVPL,XPO7,DNAH1,DOPEY1,KIAA1958,ELL,MCAM,ZNF354A,CEP290,PRF1,ATP6V0D1,AKAP11,HSD17B14,ZNF629,RANBP6,CAMKK2,OBSCN,ZNFX1,PRDM1,DNAH14,TBC1D2,MGAT2,NAP1L5,SYCP2L,GRIK4,UBAP2,ITPRIPL1,KIAA0355,FAT1,EXOC4,HK2,PPP1R12B,DTD1,ZFP90,ZBTB24,NR2C2AP,BCCIP,ASH1L,ARID2,SMARCA4,SLC9B2,TNKS1BP1,PPP1R9A,GBF1,DHX35,ZNF121,SEMA6A,FDX1,SBDS,ZSCAN5A,CAD,VPS18,GRIN2C,PPFIBP1,BCAP29,MYH15,AKNAD1,ITGAX,MET,CTC1,SEC24A,SOBP,KDM3B,ANKRD33B,CPOX,POU2F1,VIM,EDEM2,NHSL1,ENC1,NUP214,UBR4,WARS,IFT81,DUS3L,ADNP,ARNTL,INTS9,PRRT3,NFRKB,PUS1,USP11,SMG1,ZNF507,DNAJC2,AUH,SH2D3A,MAP3K13,DBF4,CLSTN2,C14orf159,SEMA3E,ENOX1,FOXP1,ANKRD54,NDUFV1,GART,SEC24C,IFIT5,TANK,STC2,PRICKLE2,PCK2,FBL,DNMBP,ABCF2,PSMC3IP,PPP1R21,MARS,ARHGAP32,MEN1,ZNF407,NEU1,RERE,SRBD1,GPC2,GADD45A,MPP7,BCAS3,ITGB4 |
| 2.014e-04 | -8.51 | APRELIKOVA_BRCA1_TARGETS | MSigDB lists | APRELIKOVA_BRCA1_TARGETS | 48 | 16 | 17758 | 2279 |
HMGA2,SARS,TUBA1A,EIF3C,DDX24,VIM,STAM,FGFR1,WARS,DDX3X,EPRS,FGFBP1,ANXA5,EIF2S1,TPM1,SPTAN1 |
| 2.016e-04 | -8.51 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I | 109 | 28 | 17775 | 2278 |
GARS,BRAF,NRAS,PTBP2,NF1,ATRX,PRDM16,THSD4,ATF7IP,AGAP1,NAALADL2,TPK1,GNAI1,DOT1L,RAD54B,LRP1B,ABCA12,NME7,TBC1D22A,PDE10A,CLCN6,KIAA1328,RNF130,NRP1,KIAA1549,DENND1A,PARD3,CEP128 |
| 2.021e-04 | -8.51 | MODULE_432 | MSigDB lists | MODULE_432 | 15 | 8 | 17758 | 2279 |
LSS,MVK,IDI1,FDPS,SQLE,DHCR7,FDFT1,HMGCR |
| 2.024e-04 | -8.51 | POSITIVE_REGULATION_OF_TRANSCRIPTION | MSigDB lists | POSITIVE_REGULATION_OF_TRANSCRIPTION | 142 | 34 | 17758 | 2279 |
EGR1,TRERF1,FOXO1,NPAS2,PPARGC1B,TCF3,ATF7IP,RSF1,FOXO3,BMP6,MAP2K3,PSMG4,PHF5A,GTF2H1,NRIP1,MAML3,KAT8,ATF4,CAMKK2,KDM5A,SMARCD3,ARID1A,SUPT5H,DYRK1B,SMAD3,NSD1,SUPT4H1,SMARCC1,HIF1A,MKL2,ARNTL,TNFRSF1A,RUNX1,KAT6A |
| 2.038e-04 | -8.50 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | 188 | 42 | 17758 | 2279 |
WDR75,SARS,MCM6,CAMK1,ALG8,CENPB,LETMD1,CCDC47,POP5,FRRS1,RNF141,ACOT11,C16orf58,PRADC1,PRPS1,AKAP11,NUDC,VPS13B,USE1,NARS2,RFC4,IL11RA,APEX1,FOXN3,RDH10,PSMA1,IMPDH2,EVI5,MTR,ECH1,TBC1D2,PDE8B,PGD,ZRANB3,TRIB3,ALAD,KLF4,SDCCAG8,FDPS,BIVM,ZRANB2,NDUFS5 |
| 2.038e-04 | -8.50 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_DN | 188 | 42 | 17758 | 2279 |
SNX27,TRPM2,PRPF31,LARS2,ITFG1,NDUFB5,VPS45,FAN1,NFX1,SLC25A12,C14orf159,HLTF,PARN,FAM8A1,DUS4L,UCHL5,ATIC,NISCH,CTR9,OGG1,SNAPC5,MTHFD1,NIPSNAP1,RFC4,FAM172A,ANKMY2,KCNMA1,TYW1,ARHGEF10,SMARCD3,C11orf49,FKBP3,CLNS1A,KLHL22,VPS13C,SRBD1,HERC1,POLR3E,CCDC85B,ATM,HMBS,ZMAT3 |
| 2.038e-04 | -8.50 | envelope | cellular component | GO:0031975 | 1063 | 174 | 17570 | 2233 |
IMMP2L,CYP24A1,LETM1,DDX19A,MRPL10,PLRG1,CERS5,TMEM109,SLC25A21,RNF43,PRKCA,COA1,NUP160,COX10,LPIN1,CIAPIN1,AMBRA1,NOS1AP,MRPS30,DST,PMAIP1,ATP5G2,LETM2,MAD1L1,RAN,NDUFA6,SLC25A23,SEH1L,MPST,TIMM50,TMPO,GDAP1,TXLNG,CDK4,MCL1,SHISA5,COTL1,KCNH2,FOXRED1,FLVCR1,MPC1,MGST1,STOML2,TIMM44,DDX3X,DNAJC1,MPV17,FIS1,CLU,UQCC2,SLC25A26,MTCH1,HERC2,AK2,PIK3R4,HSD17B10,XPO7,TIMM10,CMTM3,NDUFS7,PI4KB,TNPO3,GTF3C3,ALDH18A1,MRPL21,COQ3,TOMM34,NIPSNAP1,TIMM8B,RANBP6,BDNF,SIGMAR1,RB1CC1,POLA1,RAP1GAP2,BCS1L,PLCB1,CPT1A,CYB5B,ABCF1,C19orf70,CAT,KPNA1,TRAP1,LEMD3,SURF1,HK2,DHCR7,CPT1C,NDUFA5,SUCLG1,PAFAH1B1,NDUFAF2,PDK4,NDUFB5,NUP43,SLC9B2,SLC25A44,MIEF1,NDUFB3,TERF2IP,ABCA12,NUP133,MRPS27,RMDN3,ADCK4,MTHFD2L,TMEM120B,TMEM14C,IPO11,HTRA2,HN1,ACSL5,SFXN4,CPOX,NLN,TOR1AIP2,NUP214,SNCA,ATP5D,TAMM41,SMAD3,RANBP2,KPNA3,PEMT,TIMM17A,SLC25A11,RPS6KB1,FAHD1,CEP170,TMEM33,DNAJC2,SLC25A12,LETMD1,CHCHD10,RTN4,OPA1,POM121,SLC25A20,MRPS11,ABL1,NDUFV1,ANXA7,TRIAP1,PMPCA,PRICKLE2,PTGS1,SHMT2,SLC25A1,NAV3,WDFY3,TMEM126B,TMEM126A,ABCF2,MRPS10,RANGAP1,EXOG,RHOT2,GUF1,CHCHD6,ANXA1,MRPL36,MFN2,RETSAT,ETFDH,COQ9,SLC25A19,AEN,NDUFAF5,NDUFS5,GPAM,PGAM5,UQCC1,IPO4 |
| 2.056e-04 | -8.49 | RNA helicase activity | molecular function | GO:0003724 | 66 | 20 | 16491 | 2164 |
SKIV2L,DDX28,DDX41,DDX24,SKIV2L2,DDX18,DDX19A,EIF4A2,DHX34,DDX49,DHX35,DHX57,RAD54B,DDX3X,DDX56,DDX50,DHX37,DHX33,DDX31,DDX10 |
| 2.061e-04 | -8.49 | WD40 | pfam domains | PF00400 | 203 | 45 | 16629 | 2165 |
DMXL2,WDR75,GNB3,PAFAH1B1,WDR13,PLRG1,PIK3R4,WDR26,WDR37,NUP43,CORO6,NBEAL1,DENND3,NLE1,PEX7,WDR27,PAK1IP1,NBEA,CORO1A,UTP4,SEH1L,PRPF19,WDR36,FBXW4,WDR61,WDFY3,TLE3,WDR18,UTP15,WDR25,WDHD1,PWP1,GEMIN5,ELP2,WDR5B,TSSC1,WDR7,PRPF4,TBL1X,APAF1,WDR33,WDR66,BRWD3,DCAF5,CORO2B |
| 2.061e-04 | -8.49 | nucleoside-triphosphatase activity | molecular function | GO:0017111 | 763 | 134 | 16491 | 2164 |
CGN,GNB3,ATRX,KIF5A,DDX19A,TUBE1,HLTF,RAC3,RAP1A,LONRF2,DHX33,XRCC2,MYH3,CHD2,RAN,LONP1,CHD9,ABCC4,SKIV2L2,KATNAL1,GNL3,HSPA5,KIF15,ABCC2,MCM2,DDX60,LSG1,PEX1,KIF16B,GNAI1,RHOU,DDX3X,RAD18,CHD3,EEFSEC,RAD51B,ABCC3,DNAH2,DIRAS1,CLU,EP400,MCM6,AK6,RSF1,CHD5,DNAH1,ABCA7,DDX56,DHX37,ABCA5,MCM5,GTF2H1,ATP6V0D1,DDX28,GTF2H3,MYO10,EIF4A2,RAP1B,ABCF1,DNAH14,ATP9B,DYNC1H1,ASCC3,NSF,DNAH17,RRAGA,GPN1,DDX10,DNM3,ABCA3,DDX18,ATP6V1A,HFM1,MYO7A,OLA1,SMARCA4,MYH9,TUBB6,MCM9,DDX60L,DHX35,HSPA1A,CHD7,ABCA12,MYH15,MSH4,GNG5,ATP6AP1L,SKIV2L,PMS1,RFC4,RFC3,TUBA1A,DDX41,RAB7A,MTIF2,ATP6V0A1,GNL1,ATP8B2,RAB10,DHX57,RAD54B,ATP5D,MDN1,SEPT5,RAB30,VWA8,C10orf2,KLC4,KIF5C,ATF7IP,MLH1,OPA1,GFM2,DDX31,DYNC2H1,TOP1,DDX24,SMARCAD1,ABCF2,DHX34,EIF5B,GUF1,RHOT2,DDX49,MFN2,HSPA1B,ANXA1,ZRANB3,SRCAP,DDX50,HELZ,MSH3,KIF1B |
| 2.064e-04 | -8.49 | REACTOME_HIV_LIFE_CYCLE | MSigDB lists | REACTOME_HIV_LIFE_CYCLE | 109 | 28 | 17758 | 2279 |
GTF2H3,VPS37A,TAF1,RNMT,TCEB3,LIG4,RANGAP1,NUP43,SUPT5H,NUP214,POLR2A,POM121,RANBP2,ELL,SUPT4H1,GTF2A1,NUP133,CCNT1,CDK9,BANF1,TAF4,VPS37B,GTF2H1,NCBP2,RAN,TAF12,XRCC4,SEH1L |
| 2.066e-04 | -8.48 | MARSON_BOUND_BY_E2F4_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_E2F4_UNSTIMULATED | 692 | 121 | 17758 | 2279 |
RTTN,PIGM,PCNT,ATRX,TBCCD1,RSL1D1,TUBE1,PPIL1,HLTF,TTI1,GABPB2,PELP1,SBDS,RPP30,FLAD1,C1orf159,SHC1,ACD,YLPM1,ERI1,NUP133,RASSF3,PYCRL,SETD5,XRCC2,INTS12,JOSD1,POLE3,OGG1,C6orf89,CASP8AP2,IPO11,CTC1,TIMM50,CEP128,PRPF19,RFC4,NOL8,AP4B1,KIF15,HIST1H2BL,GSTCD,SLC9A5,FKBP3,C1orf174,EXO1,TMCO1,BRCA2,ALAD,LRRC40,NSMCE1,H2AFX,RAD51B,TRMT2A,EME1,FIP1L1,NOLC1,TXN2,XRCC4,MUTYH,MCM6,SHQ1,MCM10,AK2,DROSHA,SCAMP3,ITPRIP,XPC,FAM189B,FAM46B,TCF3,ALG8,TATDN3,MED18,OPA1,RNASEH2B,RPS6KA5,PITPNM1,C15orf57,COMMD9,INTS7,APLF,MCM5,MYC,C15orf41,C12orf4,SNAPC5,SERBP1,ULBP1,C21orf58,EXOSC2,TTLL5,PRIM2,KIAA1143,GINS3,PPAT,POLA1,HAUS6,TYW1,PSMC3IP,SCFD2,TOP3A,RANGAP1,HIST1H4J,NOP58,CCDC150,NEU1,POLR2A,CENPP,TOE1,UBAP2,PALB2,GTF2A1,NME7,POLE2,RIOK3,MSH3,CNOT6,HMBS,LMBRD2,SLC16A10 |
| 2.066e-04 | -8.48 | transcription from RNA polymerase III promoter | biological process | GO:0006383 | 43 | 15 | 16441 | 2138 |
ELL,POLR3D,POLR3E,CRCP,POU2F1,ICE2,GTF3C3,POLR3B,POLR1C,ZC3H8,SNAPC4,TROVE2,POLR3A,SNAPC5,POLR3G |
| 2.069e-04 | -8.48 | MENSE_HYPOXIA_UP | MSigDB lists | MENSE_HYPOXIA_UP | 93 | 25 | 17758 | 2279 |
PFKFB4,KLHL24,INSIG2,PDK1,ERICH1,JMJD6,BHLHE40,FAM13A,NOL3,SERGEF,ANGPTL4,ZBTB25,NAMPT,PLIN2,INSIG1,GADD45A,KDM4B,KLF4,STC2,RIOK3,HK2,PEX13,RBPJ,KDM4C,STK4 |
| 2.071e-04 | -8.48 | cyclohydrolase activity | molecular function | GO:0019238 | 6 | 5 | 16491 | 2164 |
MTHFD1L,MTHFD2,MTHFD2L,ATIC,MTHFD1 |
| 2.072e-04 | -8.48 | CTTGTAT,MIR-381 | MSigDB lists | CTTGTAT,MIR-381 | 194 | 43 | 17758 | 2279 |
SSH2,PRPF38B,BIRC6,ACTG1,UBN1,KHDRBS1,NHS,MED13L,XPO7,SLC6A8,UBR5,SCAF8,NAMPT,UBE3A,UBR1,SLC38A2,PDS5B,NBEA,RNF111,ETF1,RNF2,C15orf41,NAV3,HMBOX1,STAG1,NFIA,VSNL1,R3HDM1,R3HDM2,SOX4,MBNL2,NAP1L5,ZFAND3,SYNCRIP,KPNA3,INSIG1,HNRNPR,KLF4,SEMA3C,RPS6KB1,IQSEC2,ZNF532,KIF1B |
| 2.076e-04 | -8.48 | nucleotide metabolic process | biological process | GO:0009117 | 443 | 84 | 16441 | 2138 |
NDUFA5,ATP6V1A,NDUFB5,OLA1,NT5C3A,COX10,PUDP,HSPA1A,PDE3A,NDUFB3,FLAD1,CAD,AMPD3,ATP5G2,PPCDC,MYH3,NT5C,ME1,FHIT,CMPK1,NDUFA6,FXN,MTHFD2L,OGG1,MCEE,GARS,ITPA,UPP1,DLG4,ATP6V0A1,NUDT15,DLST,PDE8B,ATP5D,STOML2,SNCA,HPRT1,DCXR,G6PD,MUTYH,AK2,SULT1C2,AK6,PDE4B,CHCHD10,APRT,RNASEH2B,NDUFS7,NAMPT,GART,NDUFV1,ENTPD5,ATIC,PDE10A,NT5M,PRPS1,NT5E,HMGCR,MTHFD1,PFKFB4,BDNF,PDE4A,PPAT,SMARCAD1,IDH3G,LDHA,SULT4A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,PGD,CAT,NME7,COQ9,HK2,TBPL1,SURF1,UMPS,NDUFS5,BPNT1,ADK,PDE9A |
| 2.095e-04 | -8.47 | soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal | 2752 | 411 | 17775 | 2278 |
GGT1,MYCBP2,CGN,DCP1B,CACNA1H,SYNJ1,UBR5,RAC3,LPIN1,SKI,GIPR,C1orf159,PDZD2,ZFHX3,MAD1L1,RNF111,HRG,AVEN,SRRM2,CSGALNACT2,ZNF646,ACADS,CCDC57,SLC38A6,NRAS,NFIA,TCEB3,CUX1,RFX2,EFHC1,ABCC2,ZDHHC14,DENND4A,SON,SLC50A1,OSBPL1A,BRCA2,TRRAP,VPS13D,TXN2,BLMH,ZNF598,PTPN14,EP400,WDR75,IFT57,JUP,CELSR1,ZHX3,DLGAP4,PIK3R4,CCDC47,PARN,CDC73,CD226,ABCA7,FAM192A,SH2B3,NAV1,HR,INTS7,COPS3,GTF3C3,ANP32B,CCDC88C,COQ3,AGL,FMNL2,SIK3,COL17A1,KCNQ3,RREB1,RB1CC1,PRDM16,ARID5B,RYR2,PTPN12,TTYH2,SMARCD3,MAP7D1,ARID1A,TRIM37,EVI5,ANGPTL4,MTR,LYRM7,ARIH2,IRS1,DYNC1H1,VPS13C,LRP1B,PDLIM1,SRP68,ZZEF1,D2HGDH,ZNF160,DPEP1,CNDP2,ZFHX2,TBKBP1,AMOTL1,SYT17,TRPM2,NDUFB5,MYH9,AGAP6,ISG20L2,PABPC1L,LTB4R,TRIM66,RPGRIP1L,CHD7,DECR1,TMEM184A,KDM2A,FMNL1,VGF,WAC,CLCN6,TTC3,PEG10,DENND1A,RFC4,KMT2D,GON4L,FAM111B,EIF3J,WDPCP,ARHGEF10,DLG4,GNL1,MED16,TTC28,FGFR1,DCBLD2,ZFAND3,DNAJA3,HIPK2,G6PD,METTL6,ACP1,IFT140,MDN1,PDCD11,YEATS2,BAG1,MAPT,MORC2,NCOR2,BRAF,RCAN1,RTN4,ATG2B,MLH1,BHLHE40,INPP1,PSMF1,NEDD4,ABL1,UNC13A,ACOT11,UPF2,ARHGAP1,SOX6,HNRNPM,SPTAN1,DIS3L2,DDHD1,C21orf58,ERICH1,POLK,LDHA,ZNF467,CCDC150,YIF1A,ZFP62,NSD1,RARS,PXDN,DDX50,HERC1,STX18,ATM,PTPN4,MYOM2,GPAM,SORCS2,DOCK6,CUL7,LETM1,MVK,PHF3,TRIM16,RBM33,NF1,KIF5A,PPARGC1B,MFGE8,FANCD2,TRPM6,RNF43,STK33,SEC16A,SCAF8,SNAPC4,MAP2K3,FRRS1,SLC30A7,SMARCB1,ZNF804A,YLPM1,THADA,LONRF2,TRMU,MYH3,KIAA0922,NDUFA6,OGG1,CARM1,MPST,VPS13B,DSC3,FLNC,METTL1,FBXW4,MIOS,ABCC4,BAZ2A,ITPA,ANK2,ARRDC3,LAMA2,BRCA1,KMT2C,KCNH2,TCTN1,PEX1,BSN,CCDC3,DYRK1B,GEMIN5,TMEM132B,MSRA,TP53BP1,TNFRSF1A,CSMD3,ADAM9,EME1,MTCH1,SLC12A7,DCTN3,ITFG1,PRSS3,SMAD7,HES6,PCSK7,SMG7,RLF,ARID1B,DNAH1,DOPEY1,MCAM,CEP290,PDE10A,WDR27,VAPB,SYNJ2,PRF1,CWF19L2,NRIP1,NT5E,ZNF629,MTHFD1,KRT20,HBG2,PDE4A,SETD2,ZBED4,HAUS6,BCS1L,OBSCN,WWC1,ANKRD20A4,AGAP1,ACOXL,DNAH14,ISG15,TCF7L2,ATXN7,SPAG9,MYBBP1A,PALB2,EP400NL,FAT1,SNAP23,DNAH17,HK2,CASS4,ZFP90,TMEM182,TBCK,BCCIP,DMXL2,PCNT,UPK3B,PAPD4,ARID2,CELSR3,TNXB,MYO7A,SMARCA4,ZNF83,DENND3,RADIL,DDX60L,ZNF121,FDX1,PLXNB1,VPS18,JAG1,NUP133,DNAJB6,ARMC5,CCDC40,HIBCH,MYH15,MET,ZNF460,HTRA2,CTC1,CASP10,TMEM200A,SEC24A,KDM3B,NARS2,WDR36,PCGF3,SSFA2,GLTSCR2,THSD4,ANKRD33B,PARP2,RAB7A,MANBAL,ATXN1,AKAP13,EDEM2,ATP8B2,NUP214,UBR4,BTBD11,ATP5D,EXO1,ARMC4,SLC30A3,LMBR1L,HYAL3,SIX5,ZNF333,INTS9,TSSC1,PRRT3,DISP1,NFASC,MUTYH,SMG1,ZNF507,ATXN7L2,NSUN6,MAP1S,ATF7IP,RBM19,FOXP1,RMI1,POGZ,BZW2,MFSD10,SFI1,ZNF594,IQGAP2,PRICKLE2,POLR1B,CPNE7,ERI3,RPS6KB2,KDM6B,ADAMTSL3,LRRIQ1,CRIM1,METTL23,SCFD2,C11orf49,TMEM187,SYMPK,ARMC3,SMPDL3B,NEU1,RERE,ZRANB3,TPD52L2,DAGLB,DSC2,WDR35,TAF4,BCAS3,USP20,ZRANB2,RBPJ,NR2F2,MMP16,ZAK |
| 2.095e-04 | -8.47 | embryonal | COSMIC cancer mutations | embryonal | 2752 | 411 | 17775 | 2278 |
GGT1,MYCBP2,CGN,DCP1B,CACNA1H,SYNJ1,UBR5,RAC3,LPIN1,SKI,GIPR,C1orf159,PDZD2,ZFHX3,MAD1L1,RNF111,HRG,AVEN,SRRM2,CSGALNACT2,ZNF646,ACADS,CCDC57,SLC38A6,NRAS,NFIA,TCEB3,CUX1,RFX2,EFHC1,ABCC2,ZDHHC14,DENND4A,SON,SLC50A1,OSBPL1A,BRCA2,TRRAP,VPS13D,TXN2,BLMH,ZNF598,PTPN14,EP400,WDR75,IFT57,JUP,CELSR1,ZHX3,DLGAP4,PIK3R4,CCDC47,PARN,CDC73,CD226,ABCA7,FAM192A,SH2B3,NAV1,HR,INTS7,COPS3,GTF3C3,ANP32B,CCDC88C,COQ3,AGL,FMNL2,SIK3,COL17A1,KCNQ3,RREB1,RB1CC1,PRDM16,ARID5B,RYR2,PTPN12,TTYH2,SMARCD3,MAP7D1,ARID1A,TRIM37,EVI5,ANGPTL4,MTR,LYRM7,ARIH2,IRS1,DYNC1H1,VPS13C,LRP1B,PDLIM1,SRP68,ZZEF1,D2HGDH,ZNF160,DPEP1,CNDP2,ZFHX2,TBKBP1,AMOTL1,SYT17,TRPM2,NDUFB5,MYH9,AGAP6,ISG20L2,PABPC1L,LTB4R,TRIM66,RPGRIP1L,CHD7,DECR1,TMEM184A,KDM2A,FMNL1,VGF,WAC,CLCN6,TTC3,PEG10,DENND1A,RFC4,KMT2D,GON4L,FAM111B,EIF3J,WDPCP,ARHGEF10,DLG4,GNL1,MED16,TTC28,FGFR1,DCBLD2,ZFAND3,DNAJA3,HIPK2,G6PD,METTL6,ACP1,IFT140,MDN1,PDCD11,YEATS2,BAG1,MAPT,MORC2,NCOR2,BRAF,RCAN1,RTN4,ATG2B,MLH1,BHLHE40,INPP1,PSMF1,NEDD4,ABL1,UNC13A,ACOT11,UPF2,ARHGAP1,SOX6,HNRNPM,SPTAN1,DIS3L2,DDHD1,C21orf58,ERICH1,POLK,LDHA,ZNF467,CCDC150,YIF1A,ZFP62,NSD1,RARS,PXDN,DDX50,HERC1,STX18,ATM,PTPN4,MYOM2,GPAM,SORCS2,DOCK6,CUL7,LETM1,MVK,PHF3,TRIM16,RBM33,NF1,KIF5A,PPARGC1B,MFGE8,FANCD2,TRPM6,RNF43,STK33,SEC16A,SCAF8,SNAPC4,MAP2K3,FRRS1,SLC30A7,SMARCB1,ZNF804A,YLPM1,THADA,LONRF2,TRMU,MYH3,KIAA0922,NDUFA6,OGG1,CARM1,MPST,VPS13B,DSC3,FLNC,METTL1,FBXW4,MIOS,ABCC4,BAZ2A,ITPA,ANK2,ARRDC3,LAMA2,BRCA1,KMT2C,KCNH2,TCTN1,PEX1,BSN,CCDC3,DYRK1B,GEMIN5,TMEM132B,MSRA,TP53BP1,TNFRSF1A,CSMD3,ADAM9,EME1,MTCH1,SLC12A7,DCTN3,ITFG1,PRSS3,SMAD7,HES6,PCSK7,SMG7,RLF,ARID1B,DNAH1,DOPEY1,MCAM,CEP290,PDE10A,WDR27,VAPB,SYNJ2,PRF1,CWF19L2,NRIP1,NT5E,ZNF629,MTHFD1,KRT20,HBG2,PDE4A,SETD2,ZBED4,HAUS6,BCS1L,OBSCN,WWC1,ANKRD20A4,AGAP1,ACOXL,DNAH14,ISG15,TCF7L2,ATXN7,SPAG9,MYBBP1A,PALB2,EP400NL,FAT1,SNAP23,DNAH17,HK2,CASS4,ZFP90,TMEM182,TBCK,BCCIP,DMXL2,PCNT,UPK3B,PAPD4,ARID2,CELSR3,TNXB,MYO7A,SMARCA4,ZNF83,DENND3,RADIL,DDX60L,ZNF121,FDX1,PLXNB1,VPS18,JAG1,NUP133,DNAJB6,ARMC5,CCDC40,HIBCH,MYH15,MET,ZNF460,HTRA2,CTC1,CASP10,TMEM200A,SEC24A,KDM3B,NARS2,WDR36,PCGF3,SSFA2,GLTSCR2,THSD4,ANKRD33B,PARP2,RAB7A,MANBAL,ATXN1,AKAP13,EDEM2,ATP8B2,NUP214,UBR4,BTBD11,ATP5D,EXO1,ARMC4,SLC30A3,LMBR1L,HYAL3,SIX5,ZNF333,INTS9,TSSC1,PRRT3,DISP1,NFASC,MUTYH,SMG1,ZNF507,ATXN7L2,NSUN6,MAP1S,ATF7IP,RBM19,FOXP1,RMI1,POGZ,BZW2,MFSD10,SFI1,ZNF594,IQGAP2,PRICKLE2,POLR1B,CPNE7,ERI3,RPS6KB2,KDM6B,ADAMTSL3,LRRIQ1,CRIM1,METTL23,SCFD2,C11orf49,TMEM187,SYMPK,ARMC3,SMPDL3B,NEU1,RERE,ZRANB3,TPD52L2,DAGLB,DSC2,WDR35,TAF4,BCAS3,USP20,ZRANB2,RBPJ,NR2F2,MMP16,ZAK |
| 2.099e-04 | -8.47 | TOOKER_GEMCITABINE_RESISTANCE_DN | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_DN | 120 | 30 | 17758 | 2279 |
CYP24A1,MSX1,SLC3A2,PSAT1,GNL3,LGALS1,AKAP12,MARS,CYB5B,EHBP1,PIK3CB,FKBP3,OSBPL1A,SLC39A14,TRIB3,ASNS,PTRF,SLC7A11,PPID,VCAN,SHMT2,CLU,SERPINH1,PTP4A2,LPCAT1,AVEN,XRCC4,YARS,MTHFD1,TOP1 |
| 2.100e-04 | -8.47 | Resolution of D-loop Structures through Holliday Junction Intermediates | REACTOME pathways | R-HSA-5693568 | 33 | 13 | 8202 | 1117 |
EXO1,RBBP8,BRCA2,SLX4,PALB2,XRCC2,RAD51B,TOP3A,ATM,BRCA1,EME1,RMI1,SPIDR |
| 2.107e-04 | -8.46 | central_nervous_system-brain-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_III | 1482 | 235 | 17775 | 2278 |
ARHGAP26,ZNF292,PHF3,NF1,ATRX,KIF5A,PPARGC1B,SLC25A21,BCOR,FAM13A,PRKCA,SEC16A,SNAPC4,AMBRA1,PCDH7,SMARCB1,RTN1,ZNF804A,ARHGAP18,ZFHX3,YLPM1,THADA,SYN2,MARVELD2,RASSF3,ANAPC11,MAD1L1,PDS5B,ME1,FTSJ3,LONP1,DSC3,DTNB,CHD9,ZNF124,NRAS,ABCC4,HARS,RNMT,PTPRM,EXOC6B,ANK2,RFX2,KSR2,PLEKHM3,LAMA2,BRCA1,SGK2,ZDHHC14,SON,ZNF91,GNAI1,SLC7A1,GLS,BRCA2,TRRAP,INSIG1,SUFU,BDH2,CSMD3,DPP4,SEMA3C,DNAH2,GALNT10,ZMAT3,PTPN14,USP15,EFNB2,OXNAD1,IFT57,DROSHA,CELSR1,LRRC28,NKD2,OPHN1,GTF2IRD1,MED13L,IGF2BP3,CHN1,TECTA,RNF40,PRKCE,ELL,CNST,SLC38A5,ABCA5,ISPD,SEMA3D,CCDC167,SLC16A9,SAMD13,ANP32B,GMDS,ZCCHC7,PABPC1,SERBP1,SNX29,NT5E,RANBP6,IFRD1,TRAPPC9,ALG6,KCNQ3,PRIM2,PRDM16,ELOVL6,ARID5B,RAPGEF4,SETD2,ZFP14,WDR25,RYR2,SMARCD3,OBSCN,ST6GALNAC3,CORIN,PLCB1,MBNL2,SLC26A11,DNAH14,TCF7L2,ATP9B,VPS13C,LRP1B,ZZEF1,FAT1,SDCCAG8,MED15,EXOC4,SNX24,TMEM117,PPP1R12B,PDLIM5,PRKAR2A,USP7,TRPM2,ZNF516,UPK3B,PCNT,ARID2,HFM1,VTI1A,SMARCA4,LPCAT3,PTPRG,ARSJ,LCLAT1,PPP1R9A,EEA1,RAET1E,CAD,ZNF827,BRE,ABCA12,RPS6KL1,SNTG2,CCDC40,MYH15,FHIT,MET,PHLDB2,GARS,KMT2D,COL5A2,FAM172A,EIF3J,SFSWAP,SLCO6A1,PCNXL2,UBR4,FGFR1,USP36,ARMC4,MSX2,CAMK2D,KLF4,CLEC16A,ATG7,WDR7,LARGE,EIF2B3,ANKS1A,SMG1,PARD3,COMMD10,HMGA2,BRAF,TTC27,KLC4,CLSTN2,WDR37,IGF2BP2,ATF7IP,SEMA3E,MON2,MLH1,MBNL1,MFHAS1,NEDD4,MAN1A1,IQGAP2,IL17RE,PRKCH,TAF3,UNC13A,TTC17,LDLRAD3,ERI3,LARP4B,DMRT1,SAMD4A,HSD17B12,SOX6,ULBP1,CRIM1,AGPAT4,ARHGAP39,DHX34,MEN1,EIF5B,NAALADL2,POLR3A,MKX,CDH24,KLHL22,TPD52L2,SRCAP,POLE2,BCAS3,ATM,RBM26,APAF1,ZAK,MIPOL1,ZSWIM6 |
| 2.123e-04 | -8.46 | WD_REPEATS_2 | prosite domains | PS50082 | 227 | 48 | 11866 | 1504 |
DMXL2,WDR75,GNB3,PAFAH1B1,WDR13,PLRG1,PIK3R4,WDR26,WDR37,NUP43,CORO6,NBEAL1,NLE1,AMBRA1,PEX7,WDR27,PAK1IP1,CORO1A,SEH1L,LYST,PRPF19,WDR36,FBXW4,WDR61,WDFY3,TLE3,WDR18,UTP15,WDHD1,WDR25,MED16,GEMIN5,PWP1,SEC31A,WDR5B,ELP2,WDR35,HERC1,WDR7,TSSC1,IFT140,PRPF4,TBL1X,APAF1,WDR33,BRWD3,DCAF5,CORO2B |
| 2.130e-04 | -8.45 | hydrolase activity, acting on acid anhydrides | molecular function | GO:0016817 | 810 | 141 | 16491 | 2164 |
CGN,GNB3,ATRX,KIF5A,DDX19A,TUBE1,HLTF,RAC3,RAP1A,LONRF2,DHX33,XRCC2,MYH3,CHD2,RAN,LONP1,CHD9,ABCC4,SKIV2L2,ITPA,KATNAL1,GNL3,HSPA5,KIF15,ABCC2,MCM2,DDX60,LSG1,KIF16B,PEX1,GNAI1,RHOU,DDX3X,RAD18,CHD3,EEFSEC,RAD51B,ABCC3,DNAH2,DIRAS1,CLU,EP400,MCM6,AK6,RSF1,CHD5,DNAH1,ABCA7,DDX56,ENTPD5,DHX37,ABCA5,MCM5,GTF2H1,PPA1,ATP6V0D1,DDX28,GTF2H3,MYO10,EIF4A2,RAP1B,ABCF1,DNAH14,ATP9B,DYNC1H1,ASCC3,NSF,DNAH17,RRAGA,GPN1,DDX10,DNM3,ABCA3,TRPM2,DDX18,ATP6V1A,HFM1,MYO7A,OLA1,SMARCA4,MYH9,TUBB6,MCM9,DDX60L,DHX35,HSPA1A,CHD7,ABCA12,MYH15,MSH4,FHIT,GNG5,ATP6AP1L,SKIV2L,PMS1,RFC4,RFC3,DDX41,TUBA1A,RAB7A,MTIF2,ATP6V0A1,GNL1,ATP8B2,NUDT15,RAB10,DHX57,RAD54B,ATP5D,MDN1,SEPT5,RAB30,VWA8,C10orf2,KLC4,KIF5C,ATF7IP,MLH1,OPA1,GFM2,DCTPP1,DDX31,DYNC2H1,TOP1,DDX24,SMARCAD1,ABCF2,DHX34,EIF5B,GUF1,RHOT2,DDX49,MFN2,HSPA1B,ANXA1,ZRANB3,SRCAP,DDX50,HELZ,MSH3,KIF1B |
| 2.151e-04 | -8.44 | PRR11 (proline rich 11) | protein interactions | 55771 | 90 | 26 | 16036 | 2270 |
LIN28B,DDX24,GLTSCR2,RSBN1,DKC1,RBM28,PABPC4,PUM3,KRI1,PES1,POP1,PWP1,TSR1,MYBBP1A,NVL,NOP16,E2F4,GLYR1,PAK1IP1,DDX31,C7orf50,NOC3L,ZBTB11,FTSJ3,GPATCH4,ZBTB24 |
| 2.152e-04 | -8.44 | OGFR (opioid growth factor receptor) | protein interactions | 11054 | 14 | 8 | 16036 | 2270 |
TERF2IP,USP7,TRAP1,CDK4,LAGE3,FKBP5,RNF2,CDC37 |
| 2.199e-04 | -8.42 | NUP133 (nucleoporin 133kDa) | protein interactions | 55746 | 32 | 13 | 16036 | 2270 |
DYNC1H1,FLNC,DDX3X,DBN1,MYC,SIRT7,RNF2,NUP43,PSAP,ZMYM2,NUP160,UBC,SEH1L |
| 2.199e-04 | -8.42 | TAF5 (TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa) | protein interactions | 6877 | 32 | 13 | 16036 | 2270 |
TAF2,TRRAP,CDC16,GTF2A1,TAF1,TAF3,MYC,TAF4,ANAPC10,TBPL1,TAF12,SOX4,TAF9B |
| 2.205e-04 | -8.42 | PITRM1 (pitrilysin metallopeptidase 1) | protein interactions | 10531 | 11 | 7 | 16036 | 2270 |
SUCLG2,VAPB,DDX41,PRDX6,PRKCSH,RARS2,TERF2 |
| 2.205e-04 | -8.42 | GCM_NF2 | MSigDB lists | GCM_NF2 | 285 | 58 | 17758 | 2279 |
ZNF292,ASCC1,ASH1L,MRI1,MRPL10,AARS2,FAN1,MAPK8IP3,MKS1,KLHL18,RIPK1,RTN4,ATG2B,C1orf52,FOXO3,GFM2,POGZ,CIAPIN1,DENR,TOX4,FAM192A,COMMD9,DHX37,NUP133,VPS52,RAN,TTC17,ZNF710,KDM3B,RANBP6,CHD9,BAZ2A,STAMBP,TSPYL4,IDH3G,EPS15L1,UBE2K,DENND4A,EHBP1,VPS53,MFN2,TAF9B,GTF2A1,HNRNPR,INTS5,CLEC16A,LEMD3,FNTB,ASB3,COPS6,WDR33,GGT7,RPS6KC1,DHCR7,TBCK,BRD9,XPO6,COG5 |
| 2.205e-04 | -8.42 | MORF_RAD23A | MSigDB lists | MORF_RAD23A | 341 | 67 | 17758 | 2279 |
CHMP2A,DDX19A,ACTR3,LAGE3,RSL1D1,PABPC4,NDUFB3,CAD,FARSA,SREBF2,PPID,UBAP2L,SSBP1,RAN,POLE3,YARS,GNG5,SF3A1,RFC4,DEAF1,SLC3A2,GARS,NARS,SKIV2L2,NPM3,PCMT1,R3HDM1,MCM2,DKC1,SERP1,EIF3H,ATP5D,CDC16,SMARCC1,HNRNPR,COPS5,CEBPZ,ACP1,TROVE2,AP2S1,MCM6,AK2,SCAMP3,PRPF31,KHDRBS1,XPO7,HDDC2,POM121,TTC1,EIF2S2,NDUFV1,SEC24C,TNPO3,ANP32B,FBL,HNRNPM,NUDC,IFRD1,IDH3G,DDX49,TARS,POLR2A,EPRS,SET,GPN1,NDUFS5,DHCR7 |
| 2.212e-04 | -8.42 | MORF_RAP1A | MSigDB lists | MORF_RAP1A | 137 | 33 | 17758 | 2279 |
ZNF292,SPRED2,ATRX,SLC2A1,KLHL18,LIAS,TTI1,POLR3D,RAP1A,JAG1,TBC1D22A,SYNJ2,CHD9,MSX1,PRIM2,POLA1,SFSWAP,KIAA0586,BMS1,BRCA1,EIF5B,PIK3CB,MFN2,TAF2,SEC31A,HTR7,RBBP8,CHD3,HIC2,MSH3,FNTB,SLC25A11,SMG1 |
| 2.213e-04 | -8.42 | ribonucleoprotein complex subunit organization | biological process | GO:0071826 | 198 | 44 | 16441 | 2138 |
SART1,SHQ1,EIF3C,PRPF31,TFIP11,AGO2,SF3A3,NOL3,PRPF39,MBNL1,GFM2,SBDS,EDC3,DENR,MRPS11,ZNHIT6,ATXN2,CELF1,GEMIN4,PRMT5,SRPK2,PRPF19,SF3A1,SCAF11,DDX28,PTBP2,MTIF2,EIF3J,MRRF,BMS1,EIF2A,CLNS1A,EIF3H,DDX3X,GEMIN5,DYNC1H1,TSR1,BICD1,LSM14A,LUC7L3,NCBP2,MDN1,NOCT,AGO3 |
| 2.237e-04 | -8.41 | ARID | pfam domains | PF01388 | 15 | 8 | 16629 | 2165 |
KDM5B,ARID2,ARID3B,KDM5A,ARID5B,KDM5C,ARID1A,ARID1B |
| 2.241e-04 | -8.40 | NUYTTEN_NIPP1_TARGETS_DN | MSigDB lists | NUYTTEN_NIPP1_TARGETS_DN | 808 | 138 | 17758 | 2279 |
ACTG1,SEC16A,NUP160,GABPB2,SKI,S100A10,PAK1IP1,CDK6,CNTNAP3B,TMPO,OSBP2,CUX1,CAV1,MAK16,GNAI1,SLC7A1,HPRT1,AHNAK,TRMT5,ADAM9,ABCC3,GALNT10,RUNX1,VASH2,NMD3,LPP,SEPHS2,MCM6,JUP,ANKRD17,DPM3,CCDC47,CLINT1,SLC1A1,SH2B3,RNF141,KIAA1958,MCAM,ASAP1,ZNF326,SLC16A9,ZNF518B,N4BP2,PRPS1,PABPC1,CAV2,SERBP1,HMGCR,VOPP1,EXOSC2,PDE4A,LAMC1,RB1CC1,POLA1,RDH10,TTYH2,ARID1A,CPT1A,MBNL2,LYRM7,TCF7L2,EHMT2,NSF,TTC38,FGFBP1,FSCN1,RIOK3,PURB,SLC16A1,TBL1X,MAP2K4,VMA21,ZNF706,TRERF1,SLC48A1,ATP6V1A,SPRYD7,PBX1,TUBB6,ARSJ,DENR,PHC2,ESAM,TMEM184A,CCDC50,SLC38A2,CMPK1,SERPINH1,VCL,ANTXR2,MALL,PCGF3,ZCCHC14,BRD4,FAM111B,PREX1,LRRC8A,MARCH6,SETD7,ENC1,NUDT15,ERC1,STK10,RAB10,DCXR,ABHD3,H2AFX,RPS6KB1,PRRT3,TSPAN5,LAMA5,TMCC1,HMGA2,TCF3,IGF2BP2,WDR37,RTN4,AKT1S1,TGFB2,RPS6KA5,PHLDA2,DCTPP1,NEBL,CWC27,MAP3K14,LARP4B,SLC40A1,GINS3,TMEM126B,FOXN3,IL6R,INF2,TPD52L2,FBXO21,SERINC1,ACOX1,RNF138,NR2F2 |
| 2.245e-04 | -8.40 | regulation of response to DNA damage stimulus | biological process | GO:2001020 | 141 | 34 | 16441 | 2138 |
HMGA2,SPRED2,THOC5,CUL4A,NPAS2,RNASEH2B,UBR5,KDM1A,TERF2IP,ABL1,BRE,PMAIP1,TMEM161A,MYC,TRIAP1,CD44,SPIDR,OGG1,TERF2,BRD4,MSX1,APEX1,SIRT6,EYA3,MCL1,BRCA1,TAF9B,SKIL,CDK9,NSMCE1,H2AFX,ATM,CLU,BRCC3 |
| 2.287e-04 | -8.38 | RNA polymerase activity | molecular function | GO:0034062 | 43 | 15 | 16491 | 2164 |
POLR3D,PRIM2,POLA1,POLR1A,POLR3E,CRCP,MED20,POLR3B,POLR1B,POLR1C,ZNRD1,POLR1E,POLR2A,POLR3A,POLR3G |
| 2.297e-04 | -8.38 | AGTCAGC,MIR-345 | MSigDB lists | AGTCAGC,MIR-345 | 58 | 18 | 17758 | 2279 |
SPRED2,BIRC6,LSM12,CMIP,ZMYM5,NFIA,SCMH1,SLC25A12,SSBP2,ZFAND3,UBAP2,LSM14A,CACNB2,SOCS4,RNF111,FNBP1L,SLC25A26,KIF1B |
| 2.299e-04 | -8.38 | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | MSigDB lists | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | 574 | 103 | 17758 | 2279 |
FEM1C,LUZP1,NPAS2,PAFAH1B1,KIF5A,TNFRSF21,PPP2R2A,TNKS1BP1,GBF1,UBR5,GABPB2,SKI,SRSF2,CAMTA2,KDM2A,DNAJB6,JAZF1,WAC,SOCS6,NBEA,JOSD1,ZNF148,KIAA0922,CMPK1,ETV1,HN1,SOBP,CHD9,SSFA2,LIMA1,ANK2,ARHGEF10,PREX1,ATXN1,MCL1,AKAP13,SOX4,SERP1,RAB10,DCBLD2,PAF1,FBXL5,SLC30A3,IKZF4,KPNA3,ZNF236,SLC4A7,ADAM9,RUNX1,DMTF1,ZNF532,RAB30,TNRC6A,TRIM36,TMCC1,HMGA2,SSH2,MINK1,SMAD7,WDR37,TGFBR2,RPS6KA5,CHD5,SIPA1L3,SACS,RAPGEFL1,ARHGAP1,IGF2BP1,MAP3K14,CNOT4,MAP3K12,PKNOX1,GATAD2B,DDHD1,SLC40A1,WDFY3,CRIM1,RB1CC1,PPP1R21,KCNMA1,RAPGEF4,ZNF512B,ZNFX1,RSBN1,ST6GALNAC3,FAM126B,PLCB1,NAPEPLD,USP46,PHF6,FBXO21,HIF1A,L3MBTL3,SET,TBX3,PURB,PTPN4,ARHGAP12,CNOT6,TBL1X,SH3PXD2A,FNBP1L,RABEP1 |
| 2.301e-04 | -8.38 | GSE27786_LSK_VS_NKTCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKTCELL_UP | 189 | 42 | 17758 | 2279 |
WDR75,CUL7,NDUFAF2,SLK,CAMK1,DPF2,DDX19A,MEX3A,HMOX2,RSRC1,FRRS1,CAD,KIAA1958,ZNF608,IDI1,COPS4,PHKA1,MCM5,SUCLG2,GMDS,HRG,LDLRAD3,HTRA2,HSD17B12,SOX6,NUDC,FADS1,FAM127A,IL11RA,ELOVL6,BRCA1,GUF1,EXO1,EPRS,MSRA,POLE2,COPS5,FDPS,BDH2,ADAM9,TMEM158,CTXN1 |
| 2.301e-04 | -8.38 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 189 | 42 | 17758 | 2279 |
ZNF292,NDUFA5,AK2,BRAF,GPBP1L1,DBF4,LAMTOR3,GRINA,CSNK1A1,FAM50A,JOSD1,ETF1,CLDND1,EXOSC4,LPCAT1,ZMYM2,LONP1,SF3A1,FAM127A,SLC3A2,IFNGR2,KDM5B,ATG9A,ZNF654,MAPK1IP1L,TPRA1,ARL5B,PIK3CB,TAF9B,TBC1D2,OXSR1,DDX50,SPAG9,RBBP8,GTF2A1,NSMCE2,IRAK2,TRAF3,RBPJ,WDR33,IGBP1,YEATS2 |
| 2.301e-04 | -8.38 | GSE25087_FETAL_VS_ADULT_TREG_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_UP | 189 | 42 | 17758 | 2279 |
TRIP6,LUZP1,KHDRBS1,TRIO,NHS,SLC29A1,SLC39A1,SLC25A20,CAD,ZNF827,SLC7A11,BANF1,TIMELESS,WDR60,SLC25A23,GNG5,PTPRK,ARNTL2,ATF4,KDM5B,KLHL23,NPM3,HSPA5,KSR2,KIAA1586,MTHFD1L,BRCA1,MCM2,EVI5,DDX49,YTHDF2,RPA1,VDR,GNG2,TMEM237,TMEM139,CSRNP1,EIF2S1,XPNPEP1,ZAK,SRP14,CORO2B |
| 2.301e-04 | -8.38 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | 189 | 42 | 17758 | 2279 |
WDR75,ASH1L,FAM208B,SHQ1,C16orf52,SBF2,PRPF39,HSPA1A,FAM8A1,POM121,EXOC1,SRRM2,PRMT3,HMGCR,TOP1,TTPAL,SIK3,ANTXR2,PTBP2,CRIM1,FOXN3,ZMYM5,HAUS6,JMJD1C,PNN,MAT2A,PLCXD2,HSPA1B,PEX1,BTBD11,IREB2,LSM14A,CCNT1,TP53BP1,LUC7L3,MSH3,ALKBH1,RPS6KB1,SETD6,BLMH,MID1,PKIB |
| 2.323e-04 | -8.37 | V$IK1_01 | MSigDB lists | V$IK1_01 | 261 | 54 | 17758 | 2279 |
HMGA2,BCKDK,DLL4,LUZP1,ZBTB37,TNFRSF21,RNF43,FOSL2,FOXP1,LCLAT1,SEMA6A,ATXN7L1,NEK6,LRP2BP,PDE10A,VGF,RELB,ZEB1,POLR3B,POLE3,ZNF710,CDK6,SERBP1,TOP1,SOBP,MSX1,GPM6A,KIRREL2,POLA1,RDH10,VSNL1,R3HDM1,TOR1AIP2,PRDM1,BRCA1,ARID1A,ERC1,RAB10,VPS53,STOML2,C1orf122,TJAP1,NSD1,BAZ2B,AHNAK,EIF4ENIF1,KPNA3,LUC7L3,SPEN,BMP4,WDR66,FNBP1L,MMP16,USP15 |
| 2.334e-04 | -8.36 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | 195 | 43 | 17758 | 2279 |
LYRM4,NAT10,TUBB6,NUP43,CSTA,AARS,RMI1,NOP56,ZNF239,ZBED2,POLR3D,GART,SOCS1,NOP16,DNAJB6,KDELC1,GTF2H1,GEMIN4,MGLL,SEH1L,TBC1D8,PTPRK,PEA15,TIMM8B,GARS,SLC3A2,PSAT1,CDK4,PSMG1,MARS,BMS1,TARS,WARS,BATF3,VDR,SLC39A14,RBBP8,TRAP1,TP53BP1,DNAJA3,ACOX1,EIF2B3,PDCD11 |
| 2.334e-04 | -8.36 | GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP | 195 | 43 | 17758 | 2279 |
ZNF292,INSIG2,MAP2K5,PCNT,EGR1,SLC48A1,PRKAB2,PTPRG,RLF,MTUS1,CAD,CWC27,PVRL3,MYC,DSG2,PXK,LYRM5,ZMYM2,FTSJ3,TSHZ1,TLCD1,KDM6B,TRIM13,NPM3,GNL3,AP4B1,METTL15,HIST1H2BL,RBM28,C8orf33,NCDN,GZF1,UBAP2,GADD45A,DUS3L,ELP2,ZNF236,CSRNP1,DPP4,HEATR1,EIF2B3,POLR1C,TMCC1 |
| 2.334e-04 | -8.36 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | 195 | 43 | 17758 | 2279 |
CADM4,SERINC5,CELSR1,FOXO1,TNFRSF21,TRAK1,PID1,FOSL2,INPP1,SKI,GRIN2C,ACOT11,ANXA5,ZMYM2,DNMBP,CRADD,PDE4A,AGPAT4,MED27,LGALS1,C5AR1,VIM,METTL22,SLC35D1,GPNMB,PDE3B,UBC,SNCA,CTIF,VDR,MSRA,APBB3,RBBP8,KIDINS220,HIF1A,HSPB8,SGSM2,SLC4A7,RPS6KB1,PRPF4,ANXA2,MACROD1,SLC16A10 |
| 2.336e-04 | -8.36 | PACHER_TARGETS_OF_IGF1_AND_IGF2_UP | MSigDB lists | PACHER_TARGETS_OF_IGF1_AND_IGF2_UP | 35 | 13 | 17758 | 2279 |
IFRD1,SLC3A2,SESN2,ASNS,ABCA12,GADD45A,SLC7A11,SEC24D,BHLHE40,PHGDH,MID1,DDIT3,HERPUD1 |
| 2.337e-04 | -8.36 | SAM-dependent_MTases | interpro domains | IPR029063 | 121 | 30 | 18293 | 2341 |
METTL1,SRM,RNMT,METTL23,NSUN6,METTL2A,WBSCR22,PCMT1,METTL15,METTL22,GSTCD,CIAPIN1,DOT1L,METTL16,TRMT5,METTL6,ALKBH8,CAMKMT,FTSJ1,METTL8,TRMT2A,NDUFAF5,FBL,PRMT5,TRMT12,COQ3,PRMT3,FTSJ3,METTL2B,CARM1 |
| 2.360e-04 | -8.35 | regulation of cellular amide metabolic process | biological process | GO:0034248 | 319 | 64 | 16441 | 2138 |
ZNF706,EIF3C,AARS,PAIP2,ETF1,ATF4,EIF4E3,EIF3J,MTIF2,CDK4,SOX4,ENC1,SERP1,PUM3,EIF3H,DDX3X,EIF4ENIF1,DNAJC1,LSM14A,EEFSEC,PER1,TNFRSF1A,RPS6KB1,CLU,EIF2B3,UQCC2,TNRC6A,MIF4GD,LARS2,KHDRBS1,AGO2,IGF2BP2,VARS,ZFP36L1,FOXO3,GIGYF2,IGF2BP3,ABCA7,GATC,ATXN2,SELT,IGF2BP1,CELF1,LARP4B,YBX3,PABPC1,SAMD4A,RPS6KB2,EIF4A2,EIF2A,GUF1,EIF5B,ABCF1,CTIF,EPRS,IREB2,SYNCRIP,TRAP1,EIF2S1,CNOT6,NCBP2,DTD1,UQCC1,AGO3 |
| 2.360e-04 | -8.35 | YRTCANNRCGC_UNKNOWN | MSigDB lists | YRTCANNRCGC_UNKNOWN | 63 | 19 | 17758 | 2279 |
FLNC,NARS2,ZBTB37,SMARCAD1,SULT4A1,PPHLN1,SLC25A12,PITPNB,KRTCAP2,LCLAT1,PELP1,PITPNM1,ERC1,NCDN,PTPN2,SUV39H2,CDKAL1,SRRM2,MAML3 |
| 2.361e-04 | -8.35 | tRNA processing | REACTOME pathways | R-HSA-72306 | 94 | 26 | 8202 | 1117 |
METTL1,CTU2,TYW1,LAGE3,POP5,NUP43,NUP214,NUP160,POM121,RPP30,POP1,RANBP2,EPRS,TRMT5,ZBTB8OS,NUP133,TRMT13,ADAT2,ALKBH8,CDKAL1,PUS1,RAN,TSEN2,TRMT10A,TRMT12,SEH1L |
| 2.366e-04 | -8.35 | V$ATF_01 | MSigDB lists | V$ATF_01 | 249 | 52 | 17758 | 2279 |
SPRED2,AMOTL1,CYLD,RHOBTB1,NF1,MAP3K13,PAFAH1B1,RFX1,PPARGC1B,DDX19A,RPS29,RCAN1,SSR4,MBNL1,RING1,GART,BRE,MCAM,ZFHX3,INTS7,GLYR1,IKBKB,JOSD1,ETF1,RAPGEFL1,IPO11,CTC1,TERF2,TOP1,FLNC,RANBP6,FGF9,STAMBP,TLE3,AGPAT4,IDH3G,TPM4,LDHA,SULT4A1,GNL1,KRTCAP2,SON,MBNL2,NUP214,FOXRED1,TMEM175,TAF2,SPAG9,GTF2A1,ZZEF1,PER1,XPNPEP1 |
| 2.377e-04 | -8.34 | transcription coactivator activity | molecular function | GO:0003713 | 298 | 61 | 16491 | 2164 |
TRERF1,JUP,KMT2E,TAF1,PPARGC1B,TCF3,SMARCA4,BIRC2,ARID1B,LPIN1,KDM1A,SFR1,SMARCB1,TADA3,SNW1,SUB1,LPIN2,BUD31,MED24,ZEB1,RAN,NRIP1,HCFC2,CARM1,MAML3,APEX1,FGF2,PPARG,PRDM16,KDM5A,ARID5B,MED27,PSMC3IP,WWC1,SMARCD3,MED16,ARID1A,BRCA1,SOX4,SRA1,NR2F1,RERE,DYRK1B,SRCAP,TRRAP,SMARCC1,GTF2A1,PDLIM1,COPS5,HIPK2,MKL2,TAF4,PQBP1,TBPL1,PUS1,TAF12,MED20,FUS,NFKBIB,RFXAP,KAT6A |
| 2.393e-04 | -8.34 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1451 | 233 | 16441 | 2138 |
ZNF292,THOC5,TRIM16,AAMDC,GPBP1L1,KMT2E,ATRX,PPARGC1B,HLTF,CCNL2,SIRT2,GABPB2,LPIN1,MAP2K3,SKI,SMARCB1,PHF5A,SREBF2,ZFHX3,DHX33,RELB,ZEB1,RNF111,ZNF148,RAN,MEIS3,ETV1,TRIM14,DDN,ZBTB17,DEAF1,HMBOX1,TRIM13,RBCK1,ATF4,PPARG,NR6A1,GNL3,HSPA5,NFIA,TCEB3,CUX1,SUPT20H,BRCA1,SOX4,MLLT10,DDX3X,PAF1,DYRK1B,UBTF,TCF7L1,BRCA2,SUPT4H1,INSIG1,GATA6,TP53BP1,CCNT1,PER1,E2F4,MKL2,TNFRSF1A,CLU,RUNX1,DLX2,ZC3H8,RFXAP,MEF2C,BANP,FOXO1,EGR1,JUP,TAF1,PAX2,SIRT7,SMAD7,PID1,BARX2,TRIM15,ZIC2,RSF1,RLF,CDC73,ARID1B,NAMPT,ELL,SUB1,CEP290,MYC,BUD31,GTF2H1,MED24,CTR9,ICE2,NRIP1,MYB,GTF2H3,BDNF,CAMKK2,WDR61,PAXBP1,STAG1,RREB1,PRDM16,ARID5B,UTP15,SMARCD3,EIF2A,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,ONECUT2,TCF7L2,CAT,ATXN7,TASP1,HIF1A,CDK9,SPEN,IRAK2,ZFP90,TBL1X,SMYD3,TESC,TCF12,MAP2K5,ASH1L,ZNF516,TRERF1,NPAS2,DDR2,SMARCA4,PBX1,RIPK1,FOSL2,PELP1,HSPA1A,KDM1A,BLOC1S2,TERF2IP,RRN3,NRF1,JAG1,CAMTA2,IKBKB,WAC,LPIN2,MET,KMT2A,MOSPD1,MAML3,KAT8,KMT2D,BRD4,DDX41,GRHL3,ATXN1,SATB2,MED16,MEF2D,SETD7,ERC1,VDR,TAF2,SMAD3,SMARCC1,IKZF4,SIX5,COPS5,HIPK2,KLF4,CEBPZ,ARNTL,PUS1,HEATR1,HMGA2,DNAJC2,INSIG2,SUPT6H,MAP3K13,CAMK1,TCF3,AGO2,ID2,ATF7IP,TRIM22,RPS6KA5,BMP6,FOXO3,MAD2L2,SFR1,PRKCH,TADA3,SNW1,HAS3,TRIAP1,DMRT1,SOX6,PKNOX1,MBTPS2,KDM6B,ARNTL2,SLC40A1,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,IL6R,MEN1,KLF6,FOXC1,UBC,POLR2A,RERE,HSPA1B,NSD1,ARID3B,TBX3,TAF4,CSRNP1,BCAS3,NCBP2,MYRF,RBPJ,BMP4,TAF12,NFKBIB,NR2F2,IGBP1,DDIT3,KAT6A |
| 2.421e-04 | -8.33 | negative regulation of cellular metabolic process | biological process | GO:0031324 | 2309 | 354 | 16441 | 2138 |
CHAC1,PRKCA,UBR5,SKI,SREBF2,ZFHX3,ZFYVE28,MAD1L1,ZNF148,FNIP2,KDM5C,HRG,HMBOX1,NR6A1,EHMT1,NFIA,CUX1,SPOP,DOT1L,GZF1,DDX3X,SKIL,BRCA2,SUPT4H1,RAD18,CCNT1,SH3RF1,HIC2,TNFRSF10D,BMI1,SPOCK3,MEF2C,EGR1,ZHX3,KHDRBS1,SIRT7,OPHN1,PID1,RSF1,PDCD5,CDC73,ABCA7,IGF2BP3,FKBP1A,CNST,HR,MYC,IGF2BP1,PRMT5,LPCAT1,PABPC1,TERF2,MYB,HMGCR,ADARB1,ZNF675,GATAD2B,RREB1,PRDM16,ARID5B,EIF4A2,ARID1A,NELFA,PLCB1,TRIM37,ZNF425,CAT,EPRS,EHMT2,TRAP1,PMEPA1,HIF1A,CDK9,SPEN,CCDC85B,PURB,DPEP1,NCOR1,SMYD3,ZNF254,SPRED2,MAP2K5,BIRC6,PAFAH1B1,HSPA1A,RING1,PAIP2,TERF2IP,ACD,PPID,UCHL5,WAC,SOCS6,SERPINH1,CASP8AP2,SAP30,KMT2D,DLG4,SATB2,FGFR1,PDE8B,SNCA,VDR,MSX2,CDC16,SMARCC1,ELP2,HIPK2,G6PD,DNAJA3,H2AFX,TRAF3,ANXA2,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,SHQ1,INSIG2,TCF3,NFX1,ID2,GAS6,AKT1S1,TRIM22,MLH1,BHLHE40,TGFB2,NOL3,RPS6KA5,GIGYF2,FOXO3,PSMF1,MAD2L2,NEDD4,ABL1,SNW1,NPRL2,SUV39H2,TAF3,TRIAP1,CELF1,YBX3,ERRFI1,SAMD4A,SOX6,CLK2,FGF9,APEX1,ZFYVE1,NXN,UBC,TRIB3,KLHL22,NSD1,IREB2,HERC1,ATM,BMP4,IGBP1,ANAPC4,DDIT3,KAT6A,UBN1,ATRX,NF1,PPARGC1B,CSNK2A1,BCOR,SIRT2,NLE1,BIRC2,SMARCB1,ANAPC1,ECM1,SRSF2,YLPM1,JAZF1,GPR87,ANAPC11,ANAPC10,RELB,ZEB1,ZNF85,HCFC2,OGG1,TRIM14,PTPRK,DEAF1,TRIM13,RBCK1,ATF4,AEBP2,SIRT6,BAZ2A,PPARG,TFPI,MINA,GMFB,HDAC8,BRCA1,CAV1,SOX4,ZNF91,TAF9B,UBTF,PAF1,TCF7L1,EIF4ENIF1,GATA6,SUFU,INSIG1,DNAJC1,CC2D1B,PER1,SOCS4,DLX2,CLU,BEND6,ZC3H8,TNRC6A,FOXO1,PAX2,UBXN1,SMAD7,HES6,ZIC2,BARX2,DDIT4,RNF40,ELL,P3H1,MLX,MBD2,ATXN2,VPS72,SAMD11,CTR9,TIMELESS,NRIP1,PAXBP1,WWC1,PSMA1,PRDM1,SUPT5H,HERPUD1,ISG15,UBE2E1,TCF7L2,NR2F1,ATXN7,MYBBP1A,SYNCRIP,IRAK2,HK2,RRAGA,ZFP90,TBL1X,PRKAR2A,TESC,AGO3,N4BP2L2,USP7,ZNF706,DLL4,ID1,ASH1L,CYLD,FEZ2,RBFOX2,SMARCA4,RIPK1,PBX1,CSTA,PIBF1,KDM1A,ZBTB21,MPHOSPH10,SOCS1,DNAJB6,IKBKB,RNF2,FHIT,MET,PRMT3,CTC1,MOSPD1,KAT8,PRAME,PTBP2,KIRREL2,SFSWAP,POU2F1,ATXN1,ENC1,BATF3,ZC3H12A,SMAD3,RANBP2,RBBP8,IKZF4,SIX5,KLF4,ARNTL,ATG7,DUSP19,EIF2B3,PARD3,PKIB,DNAJC2,NIFK,SUPT6H,AGO2,H2AFJ,ATF7IP,IGF2BP2,PPP1R1C,SOGA1,FOXP1,HIST2H2AB,BMP6,SFI1,PTPN2,HIST2H3D,FBXO31,CD44,DMRT1,MSX1,KDM5B,CRIM1,PSPC1,FOXN3,KDM5A,DHX34,TEX14,SCMH1,HIST1H4J,MEN1,PDE2A,ZRANB3,HSPA1B,DKK1,MKX,RERE,GADD45A,TBX3,SET,GLG1,MSH3,EIF2S1,RBM26,RBPJ,NR2F2 |
| 2.455e-04 | -8.31 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 1022 | 169 | 17758 | 2279 |
TNFRSF21,NAT10,TUBE1,SIRT2,PRKCA,NBEAL1,PCDH7,DST,ZFHX3,IKZF5,YLPM1,RABGAP1L,CEP128,TBC1D8,DBN1,DEAF1,FAM127A,KATNAL1,WLS,PTPRM,EYA3,GNG7,ARRDC3,GMFB,COL4A3BP,TMEM216,SEMA3F,CAMSAP2,PLEKHM3,BRCA1,SOX4,SGK2,ZDHHC14,SAP30BP,TMEM206,PEX1,TAF9B,SKIL,TCF7L1,HSDL2,RAD18,CHD3,ARL4A,MPV17,SYNPO,DCTN3,EP400,TRIO,DLGAP4,MAPK8IP3,OPHN1,RSF1,SLC1A1,ABCA7,HR,NAV1,ENTPD5,TSPAN2,MBD2,NDRG4,PIGG,GLTP,COQ3,FMNL2,MSI2,RANBP6,TRA2A,KIAA0586,TTYH2,ATAT1,MEX3B,SYT1,EHBP1,MBNL2,CPT1A,TCF7L2,IRS1,C2orf82,KIDINS220,PPP1R12B,NCOR1,MB21D2,C12orf45,MAP2K4,PDE9A,PRKAR2A,RTTN,TCF12,SDSL,MPI,DNM3,CYLD,PAFAH1B1,SLC48A1,C16orf45,OSBPL9,KLHL18,PPP2R2A,SPATS2L,HSPA1A,PLXNB1,FLNB,ARMC6,ZKSCAN1,TBC1D22A,WAC,SOCS6,TTC3,ADCK4,MGLL,KIAA1549,ANTXR2,PHLDB2,PDK1,PNN,CCNDBP1,NHSL1,ARL5B,TBC1D16,TJAP1,VDR,CAMK2D,HNRNPR,HIPK2,ABHD3,MBTD1,NFASC,MUTYH,MAPT,ATXN7L2,KLHL24,SERINC5,MIF4GD,B4GALT5,PDE4B,RTN4,MON2,BHLHE40,FOXP1,PSMF1,TMCO6,NISCH,LDLRAD3,MICAL3,NAV3,DDHD1,TMC7,TTLL5,VPS37A,KDM5B,GINS3,ZFYVE1,AGPAT4,PSPC1,PPP1R21,HSPA1B,SRCAP,BAZ2B,PXDN,HELZ,WDR35,ACOX1,VPS37B,BCAS3,USP20,SVIL,ZNF32,NFKBIB,KIF1B |
| 2.462e-04 | -8.31 | ACTAYRNNNCCCR_UNKNOWN | MSigDB lists | ACTAYRNNNCCCR_UNKNOWN | 425 | 80 | 17758 | 2279 |
MPI,SIRT2,SRSF2,HKR1,HIRIP3,PRPF19,GDAP1,HMBOX1,SESN2,TXLNG,KATNAL1,COL4A3BP,R3HDM1,HDAC8,BRCA1,ZDHHC14,FGFR1,TMEM206,EXO1,SUFU,DUS3L,FTSJ1,INTS9,RAD51B,FIS1,PRPF4,AP2S1,RAB30,ATXN7L2,BANP,KLHL24,BCKDK,SCAMP3,CA11,ZCCHC8,OPHN1,VPS45,DPM3,ZNF691,CLINT1,COMMD9,NPRL2,SNW1,ALKBH8,KDELC1,SHMT2,CLDND1,POLR1B,PRMT5,ZCCHC7,PABPC1,RPS6KB2,MON1A,POLK,ZFYVE1,ZC4H2,RDH10,TOP3A,ZNFX1,RANGAP1,RABAC1,MTR,C19orf70,CCDC150,CTIF,RDH11,MFN2,DYNC1H1,POP1,ETFDH,EHMT2,CDK9,SDCCAG8,FDPS,BIVM,PPP1R12B,DNAJC12,FNTB,NFKBIB,SGSM3 |
| 2.494e-04 | -8.30 | MODULE_56 | MSigDB lists | MODULE_56 | 12 | 7 | 17758 | 2279 |
UMPS,APRT,HPRT1,IMPDH2,GART,ADK,PRPS1 |
| 2.523e-04 | -8.28 | WWOX (WW domain containing oxidoreductase) | protein interactions | 51741 | 244 | 55 | 16036 | 2270 |
AMOTL1,JUP,DROSHA,PRPF31,FAM189B,HSD17B10,SF3A3,CSNK2A1,SMARCA4,ENAH,IGF2BP2,PDCD7,SCAF8,HSPA1A,HNRNPA3,PABPC4,NOP56,IGF2BP3,DCTPP1,CAD,FARSA,P3H1,YLPM1,ATXN2,SEC24C,IGF2BP1,CPSF3,PRMT5,AMOT,PABPC1,SF3A1,KDM3B,TNK2,DKC1,DSP,SYMPK,POLR2A,ANXA1,PGD,GEMIN5,TOE1,UBAP2,SMARCC1,HNRNPR,HIF1A,HNRNPH3,LUC7L3,ATM,FUS,ANXA2,WDR33,FIP1L1,NOLC1,ZNF598,PTPN14 |
| 2.523e-04 | -8.28 | TRANSCRIPTION_FACTOR_BINDING | MSigDB lists | TRANSCRIPTION_FACTOR_BINDING | 305 | 61 | 17758 | 2279 |
NCOR2,TRERF1,RBFOX2,PPARGC1B,PLRG1,HES6,SMARCA4,SIRT2,TRIM22,BCOR,SNW1,SUB1,JAZF1,RELB,ZEB1,MED24,ZNF85,NRIP1,HCFC2,TRIP13,CASP8AP2,CARM1,SAP30,MAML3,KAT8,APEX1,MED27,JMJD1C,NFIA,SMARCD3,HDAC8,MED16,OASL,FOXC1,NR2F1,BATF3,DYRK1B,SKIL,TRIB3,SRCAP,NSD1,TRRAP,MYBBP1A,SUFU,GTF2A1,SMARCC1,HIPK2,COPS5,TAF4,MKL2,TBPL1,PQBP1,PURB,NCOR1,NFKBIB,NR2F2,PDCD11,RFXAP,DDIT3,STK4,KAT6A |
| 2.527e-04 | -8.28 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | REACTOME pathways | R-HSA-400206 | 115 | 30 | 8202 | 1117 |
FADS1,NCOR2,CHD9,PPARG,NPAS2,TEAD1,TNFRSF21,PPARGC1B,MED27,MED13L,SMARCD3,MED18,MED16,CPT1A,ANGPTL4,PLIN2,TRIB3,NRF1,SREBF2,ACOX1,MED15,ARNTL,MED24,ME1,TBL1X,MED20,NCOR1,CARM1,FDFT1,HMGCR |
| 2.535e-04 | -8.28 | DHX15 (DEAH (Asp-Glu-Ala-His) box helicase 15) | protein interactions | 1665 | 173 | 42 | 16036 | 2270 |
CUL7,CUL4A,FN1,DDX18,TTC27,KHDRBS1,SIRT7,SF3A3,PABPC4,NOP56,SNW1,DHX37,MYC,ATXN2,FBL,SRRM2,PABPC1,SRPK2,PRPF19,SF3A1,WDR36,KIAA1143,SKIV2L2,TMEM126B,TRA2A,NOL6,DKC1,NOP58,PUM3,UBC,RPA1,PES1,SEC31A,RANBP2,SYNCRIP,HNRNPR,COPS5,CUL2,PRPF4,SENP3,FUS,NOLC1 |
| 2.555e-04 | -8.27 | TTGGAGA,MIR-515-5P,MIR-519E | MSigDB lists | TTGGAGA,MIR-515-5P,MIR-519E | 138 | 33 | 17758 | 2279 |
KCTD7,OPHN1,CLSTN2,ZFP36L1,QSER1,TGFBR2,POM121,AHCYL2,SLC7A11,ALKBH8,ETV1,DIS3L2,ARRDC3,RAP1B,POU2F1,RSBN1,MTHFD1L,MEF2D,SNAP25,ARID1A,MARCH6,UBE2K,YTHDF2,RDH11,BSN,DDX3X,EPN2,KPNA1,UBAP2,RIOK3,GREB1L,ABCC3,C18orf25 |
| 2.564e-04 | -8.27 | cellular component assembly | biological process | GO:0022607 | 1925 | 300 | 16441 | 2138 |
CGN,ACTG1,AARS2,MKS1,SBF2,PRKCA,COA1,SYNJ1,RAC3,LPAR3,CIAPIN1,SKI,NEK6,S100A10,WIZ,ME1,CEP135,FXN,ACADS,ATG9A,LIMA1,HIST1H2BL,MCM2,FOXRED1,CLNS1A,STOML2,DDX3X,SKIL,AHNAK,LSM14A,LUC7L3,FIS1,TPM1,CCNB1IP1,SPOCK2,CLDN15,IFT57,TRIP6,JUP,PRPF31,OPHN1,RSF1,PRPF39,SLC1A1,NDUFS7,ABCA7,FKBP1A,HR,MED24,ANP32B,GEMIN4,CCDC88C,PRMT5,CAV2,HMGCR,SCAF11,DDX28,BDNF,COL17A1,RB1CC1,TSPYL4,KIAA0586,RAP1B,SNAP25,IMPDH2,CPT1A,TRIM37,ONECUT2,ANGPTL4,CAT,SEC31A,DYNC1H1,EPRS,TSR1,NSF,SURF1,KIAA0196,NCOR1,SMYD3,VMA21,DNM3,PAFAH1B1,C1QTNF7,RPGRIP1L,BLOC1S2,NUBPL,DECR1,ACD,PPID,MSH4,CEP63,KMT2A,MPP6,EIF3J,WDPCP,ARHGEF10,PREX1,DLG4,ATP6V0A1,TAF2,HLA-DMA,CAMK2D,DCXR,ARL13B,H2AFX,IFT140,MDN1,ANXA2,LAMA5,HMGA2,SHQ1,BRAF,C10orf2,SF3A3,ATG2B,GAS6,TRIM22,MLH1,CEP126,IKBKAP,NOL3,MBNL1,DCTPP1,PSMG4,NEBL,PVRL3,ANXA5,RDX,NLGN3,CELF1,DYNC2H1,PXN,CEP83,VPS37A,TTLL5,KCNMA1,ADSL,BMS1,CCDC113,PTK2,UBE2K,UBC,NDUFS5,APAF1,UQCC1,IPO4,KAT6A,IMMP2L,EIF3C,UBN1,ATRX,TRPM6,SIRT2,COX10,SEC16A,CUTC,BIRC2,EDC3,DST,ABL2,RAP1A,CNIH3,ZNHIT6,ATG3,MARVELD2,XRCC2,MYH3,LONP1,TRIP13,PTPRK,SF3A1,SRPK2,FLNC,GPM6A,SKAP2,BAZ2A,TMEM216,PSMG1,ATG12,CAV1,MGST1,BSN,CCDC28B,CHAF1A,GLS,GEMIN5,PAF1,HPRT1,E2F4,RAD51B,TNFRSF1A,BBIP1,CLU,MAGI1,UQCC2,NOCT,FBXO45,TTN,FN1,TAF1,SEC24D,VTA1,SMAD7,HSD17B10,DNAH1,SPIRE1,CEP164,CEP290,ATXN2,MBD2,PRF1,LRSAM1,POLR1E,ATP6V0D1,RANBP6,TRAPPC9,LAMC1,PPAT,HAUS6,BCS1L,OBSCN,EIF2A,TRAPPC6B,SYT1,NAP1L5,SPAG9,BICD1,FSCN1,SNAP23,TBPL1,NAPA,FNBP1L,PDSS2,AGO3,KCTD7,CHMP2A,SART1,CYLD,PCNT,CELSR3,SLC2A1,MYO7A,TNXB,COBLL1,RIPK1,PIBF1,SBDS,DENR,KCTD11,CBR4,CCDC40,CORO1A,VCL,TMEM120B,PRPF19,SEC24A,EVL,PTBP2,THSD4,RAB7A,C1QTNF1,EIF3H,SMAD3,ARMC4,IFT81,KPNA3,ALAD,NFASC,AP2S1,PARD3,TMEM33,TNIK,NIFK,HM13,MINK1,AGO2,ARFIP2,POGZ,MRPS11,HAS3,SEC24C,HIST2H3D,SHMT2,TTC17,AMOT,PPP1R9B,GPHN,SMARCAD1,FERMT2,HIST1H4J,CENPP,CDH24,TMEM237,WDR35,MPP7,SET,VPS37B,NCBP2,NDUFAF5,ITGB4 |
| 2.572e-04 | -8.27 | PUR_PYR_PR_TRANSFER | prosite domains | PS00103 | 4 | 4 | 11866 | 1504 |
UMPS,APRT,HPRT1,PPAT |
| 2.594e-04 | -8.26 | GSE17721_POLYIC_VS_CPG_16H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_16H_BMDM_DN | 190 | 42 | 17758 | 2279 |
SLC48A1,CERS5,OPHN1,CSNK2A1,WDR26,IGF2BP2,FAM8A1,MGA,ABCA7,ZNF239,MMP7,CEP290,TRIAP1,UBAP2L,PRADC1,CALN1,PRPS1,PRMT3,CAV2,CLK2,FDFT1,ACSL5,FADS1,FAM127A,WDR61,APEX1,EIF3J,CDK4,ATP6V0A1,IMPDH2,DLST,SERP1,MGAT2,TSR1,TMCO1,BICD1,ELP2,DCXR,ACOX1,FDPS,SLC4A7,BPNT1 |
| 2.594e-04 | -8.26 | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP | 190 | 42 | 17758 | 2279 |
SRM,IFT57,MCM10,C10orf2,DBF4,PPP2R2A,VARS,ISG20L2,MLH1,RPS6KA5,PDCD5,BZW2,CIAPIN1,PMAIP1,NVL,ATIC,PMPCA,GSTA4,PRMT5,POLR1E,LONP1,HNRNPM,MICAL3,TMPO,PMS1,EXOSC2,GINS3,ODC1,NUDT15,RBM28,TARS,POLR3G,EXO1,TOE1,UBAP2,SRRD,CRCP,EIF2S1,PFDN2,EIF2B3,NOLC1,BLMH |
| 2.601e-04 | -8.25 | protein methyltransferase activity | molecular function | GO:0008276 | 77 | 22 | 16491 | 2164 |
ASH1L,KMT2D,SETD1B,KMT2E,SETD2,EHMT1,PCMT1,SETD7,MEN1,KMT2C,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,FBL,PRMT5,KMT2A,SETD6,PRMT3,SMYD3,CARM1 |
| 2.610e-04 | -8.25 | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | 105 | 27 | 17758 | 2279 |
CYP24A1,ARHGAP26,POLB,THSD4,B4GALT5,TFPI,PTPN12,AKAP12,WWC1,PHACTR2,EHBP1,FOXC1,SLC23A2,CXADR,DKK1,PGD,FAT1,VCAN,KLF4,SLC38A2,C7orf50,CLU,ERRFI1,TESC,CDK6,PERP,LYST |
| 2.610e-04 | -8.25 | MORF_RFC1 | MSigDB lists | MORF_RFC1 | 105 | 27 | 17758 | 2279 |
KDM3B,GTF2H3,SIK3,CHD9,LSM12,PRKCSH,SFSWAP,VARS,MARS,BMS1,HLTF,EIF5B,PITPNM1,POLR2A,ARIH2,LPIN1,RERE,MFN2,HTR7,RANBP2,RAP1A,RBBP8,CUL2,ATM,NFRKB,BMI1,XPO6 |
| 2.622e-04 | -8.25 | TACTTGA,MIR-26A,MIR-26B | MSigDB lists | TACTTGA,MIR-26A,MIR-26B | 293 | 59 | 17758 | 2279 |
HMGA2,PTP4A1,EP400,SSH2,ADAM19,ESCO1,CELSR1,PAPD4,ARID2,HECTD3,NHS,MED13L,ADAMTS6,CHAC1,BHLHE40,RLF,SLC1A1,POM121,NAMPT,BLOC1S2,RTN1,ZNF608,RAP1A,SACS,JAG1,NEK6,SLC7A11,HAS3,ZDHHC6,SLC38A2,CLDND1,AMOT,NRIP1,FBXL19,CDK6,SERBP1,FAM98A,PHLDB2,ARHGAP17,LSM12,GRHL3,MEX3B,MCL1,ENC1,PLCB1,PHF6,NAP1L5,BAZ2B,SLC4A7,ATM,TAF12,SH3PXD2A,MMP16,ANKS1A,SPOCK2,TNRC6A,USP15,TMEM33,TMCC1 |
| 2.626e-04 | -8.25 | RNA Polymerase II Pre-transcription Events | REACTOME pathways | R-HSA-674695 | 65 | 20 | 8202 | 1117 |
GTF2H3,GTF2H2C,TAF1,AK6,TCEB3,NELFA,SUPT5H,POLR2A,TAF9B,TAF2,ELL,SUPT4H1,GTF2A1,TAF3,CCNT1,CDK9,TAF4,GTF2H1,NCBP2,TAF12 |
| 2.626e-04 | -8.25 | HDR through Homologous Recombination (HRR) | REACTOME pathways | R-HSA-5685942 | 65 | 20 | 8202 | 1117 |
RFC4,RFC3,POLK,TOP3A,BRCA1,RMI1,UBC,RPA1,EXO1,SLX4,BRCA2,RBBP8,PALB2,POLE2,XRCC2,RAD51B,ATRIP,ATM,EME1,SPIDR |
| 2.650e-04 | -8.24 | V$AHR_Q5 | MSigDB lists | V$AHR_Q5 | 202 | 44 | 17758 | 2279 |
MINK1,PCNT,RTN4,ZIC2,FOXO3,BZW2,GIT2,ZNF827,NRF1,KDM2A,IKZF5,WAC,ZEB1,VAPB,ZMYM2,BDNF,FGF9,ZCCHC14,STAG1,CMIP,EYA3,EIF4A2,POU2F1,ATG12,MEX3B,LENG8,SERP1,SLC9A5,RAB10,MLLT10,DOT1L,ZBTB25,TAMM41,CAMK2D,PALB2,INSIG1,SET,RUNX1,RBPJ,WDR33,NR2F2,BRSK2,PRKAR2A,DDIT3 |
| 2.654e-04 | -8.23 | PUJANA_BRCA_CENTERED_NETWORK | MSigDB lists | PUJANA_BRCA_CENTERED_NETWORK | 116 | 29 | 17758 | 2279 |
RFC4,RFC3,MCM6,POLA1,TCF3,CSNK2A1,BRCA1,SSBP2,MCM2,RNASEH2B,MAT2A,EIF3H,CHAF1A,RPA1,CAD,SLC7A1,SEC31A,RBBP8,BRCA2,ZNF330,COPS3,MCM5,TIMELESS,ATM,PRPF4,MED20,PRPS1,TOP1,TMPO |
| 2.672e-04 | -8.23 | V$E2F1_Q3_01 | MSigDB lists | V$E2F1_Q3_01 | 232 | 49 | 17758 | 2279 |
AK2,BRAF,CENPB,RSF1,FOSL2,SSR4,RPS6KA5,FOXO3,UBR5,GABPB2,DCTPP1,ANKRD13A,HR,INTS7,MYC,TNPO3,TTC17,ZMYM2,CDK6,C6orf89,STAG1,ENHO,POLA1,TLE3,PRDM16,IDH3G,LGALS1,ATXN1,ARHGEF12,SATB2,IMPDH2,SLC35D1,ST3GAL5,TPK1,TJAP1,YTHDF2,DDX50,SYNCRIP,GTF2A1,CDK9,KLF4,ARNTL,ZBTB12,TRMT2A,SLC25A11,SENP3,HMBS,NR2F2,SPOCK2 |
| 2.676e-04 | -8.23 | aa-tRNA-synth_Ic | interpro domains | IPR002305 | 4 | 4 | 18293 | 2341 |
WARS2,YARS,YARS2,WARS |
| 2.676e-04 | -8.23 | THF_DH/CycHdrlase_cat_dom | interpro domains | IPR020630 | 4 | 4 | 18293 | 2341 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.676e-04 | -8.23 | THF_DH/CycHdrlase | interpro domains | IPR000672 | 4 | 4 | 18293 | 2341 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.676e-04 | -8.23 | THF_DH/CycHdrlase_NAD-bd_dom | interpro domains | IPR020631 | 4 | 4 | 18293 | 2341 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.676e-04 | -8.23 | MeTrfase | interpro domains | IPR026113 | 4 | 4 | 18293 | 2341 |
METTL2B,METTL6,METTL2A,METTL8 |
| 2.679e-04 | -8.22 | TRANSCRIPTION_COFACTOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_COFACTOR_ACTIVITY | 226 | 48 | 17758 | 2279 |
NCOR2,RBFOX2,PPARGC1B,PLRG1,HES6,SMARCA4,TRIM22,BCOR,SNW1,SUB1,JAZF1,RELB,ZEB1,MED24,ZNF85,NRIP1,HCFC2,TRIP13,CASP8AP2,CARM1,SAP30,MAML3,APEX1,MED27,SMARCD3,MED16,NR2F1,BATF3,DYRK1B,SKIL,TRIB3,NSD1,SRCAP,TRRAP,SUFU,GTF2A1,SMARCC1,HIPK2,COPS5,TAF4,MKL2,TBPL1,PQBP1,NCOR1,NFKBIB,NR2F2,RFXAP,DDIT3 |
| 2.681e-04 | -8.22 | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | 220 | 47 | 17758 | 2279 |
MCM6,EGR1,SEC24D,PBX1,ENAH,SSBP2,FOSL2,RBM19,JAG1,MCAM,SHC1,KDM2A,PMAIP1,WIZ,MTHFD2L,PTPRK,HMGCR,NAV3,SEC24A,KDM6B,HMBOX1,MYO10,ELOVL6,KCNMA1,CUX1,PTPN12,MAP7D1,SATB2,MCL1,CAV1,DLST,FOXC1,BAZ1A,FBXL5,SLC7A1,MGAT2,SPAG9,INSIG1,VCAN,ACOX1,GLG1,ZCCHC6,CCDC85B,SVIL,ARHGAP12,MID1,DDIT3 |
| 2.685e-04 | -8.22 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | 792 | 135 | 17775 | 2278 |
ARHGAP26,ASCC1,THOC5,ATRX,SLC25A21,UBR5,MGA,PCDH7,ZNF804A,AMPD3,SREBF2,DHX33,ZFYVE28,THADA,RASSF3,JAZF1,ZNF148,SRRM2,TRIP13,PRKACB,SRPK2,MED27,KSR2,SAP30BP,SERGEF,TRRAP,SUFU,RAD18,RAD51B,CSMD3,DNAH2,RUNX1,NRP1,SLC25A26,PTPN14,OXNAD1,CELSR1,RHOBTB1,NHS,PID1,SMG7,RLF,SLC39A11,PRKCE,GMDS,SNX29,MYB,VOPP1,ARID5B,ZNF512B,RYR2,ST6GALNAC3,SYT1,PLCB1,EHBP1,AGAP1,MBNL2,USP46,ANGPTL4,GRIK4,LRP1B,KIAA0355,TBL1X,PTP4A2,DDX10,PDLIM5,SH3PXD2A,PDE9A,DMXL2,RTTN,NPAS2,ARID2,PDK4,NTSR1,SPATS2L,PTPRG,LCLAT1,DDX60L,PDE3A,ZC3H13,ABCA12,MRPS27,TTC3,FHIT,CEP63,ZCCHC14,PTBP2,BTBD11,ZFAND3,SLC30A3,ASTN2,CLEC16A,CAMKMT,ZNF236,WDR7,MED20,HEATR1,MID1,ANKS1A,SMG1,PARD3,TMCC1,LRCH1,DNAJA4,DYM,PDE4B,SLC25A12,CLSTN2,MON2,CSNK1A1,FOXP1,GDPD5,PSMF1,RDX,LDLRAD3,DMRT1,SOX6,HSD17B12,DIS3L2,TOP1,ARNTL2,KDM6B,TTLL5,CLYBL,NXN,PALLD,PDE2A,ARMC3,NOL10,ZDHHC11,POLE2,BCAS3,SORCS2,ADK,RPS6KC1 |
| 2.709e-04 | -8.21 | ORGANELLE_ENVELOPE | MSigDB lists | ORGANELLE_ENVELOPE | 167 | 38 | 17758 | 2279 |
RTN4,XPO7,OPA1,NUP160,TIMM10,NDUFS7,NDUFV1,ATP5G2,NUP133,PMPCA,NDUFA6,TOMM34,HTRA2,SLC25A1,TIMM50,TMPO,TIMM8B,POLA1,ABCF2,BCS1L,RANGAP1,MCL1,NUP214,RHOT2,MFN2,ATP5D,TAMM41,RETSAT,RANBP2,KPNA1,KPNA3,LEMD3,TIMM17A,MPV17,SURF1,SLC25A11,FIS1,DHCR7 |
| 2.709e-04 | -8.21 | ENVELOPE | MSigDB lists | ENVELOPE | 167 | 38 | 17758 | 2279 |
RTN4,OPA1,XPO7,TIMM10,NUP160,NDUFS7,NDUFV1,ATP5G2,NUP133,PMPCA,NDUFA6,TOMM34,HTRA2,SLC25A1,TIMM50,TMPO,TIMM8B,POLA1,ABCF2,BCS1L,RANGAP1,MCL1,NUP214,RHOT2,MFN2,ATP5D,TAMM41,RETSAT,RANBP2,KPNA1,KPNA3,LEMD3,TIMM17A,SURF1,MPV17,SLC25A11,FIS1,DHCR7 |
| 2.711e-04 | -8.21 | peptidyl-lysine dimethylation | biological process | GO:0018027 | 12 | 7 | 16441 | 2138 |
ASH1L,SETD7,SUV39H2,EHMT2,KMT2A,EHMT1,SETD2 |
| 2.732e-04 | -8.21 | recombinational repair | biological process | GO:0000725 | 148 | 35 | 16441 | 2138 |
HERC2,FAN1,RMI1,MCM9,SFR1,ABL1,BRE,SLX4,ZSWIM7,XRCC2,ATRIP,TIMELESS,SPIDR,RFC4,RFC3,SIRT6,TOP3A,HIST1H4J,BRCA1,UBC,RAD54B,RPA1,EXO1,RBBP8,BRCA2,PALB2,TP53BP1,NSMCE2,NSMCE1,H2AFX,RAD51B,ATM,EME1,BRCC3,SMG1 |
| 2.732e-04 | -8.21 | double-strand break repair via homologous recombination | biological process | GO:0000724 | 148 | 35 | 16441 | 2138 |
HERC2,FAN1,RMI1,MCM9,SFR1,ABL1,BRE,SLX4,ZSWIM7,XRCC2,ATRIP,TIMELESS,SPIDR,RFC4,RFC3,SIRT6,TOP3A,HIST1H4J,BRCA1,UBC,RAD54B,RPA1,EXO1,RBBP8,BRCA2,PALB2,TP53BP1,NSMCE2,NSMCE1,H2AFX,RAD51B,ATM,EME1,BRCC3,SMG1 |
| 2.777e-04 | -8.19 | TRANSCRIPTION_ACTIVATOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_ACTIVATOR_ACTIVITY | 173 | 39 | 17758 | 2279 |
FOXO1,PPARGC1B,SMARCA4,RSF1,FOXO3,SNW1,SUB1,PSMG4,CEP290,ZEB1,MED24,ZNF148,NRIP1,HCFC2,CARM1,MAML3,ATF4,RREB1,APEX1,KDM5A,MED27,SMARCD3,MED16,ARID1A,KLF6,NR2F1,DYRK1B,SRCAP,BRCA2,GTF2A1,SMARCC1,COPS5,TAF4,MKL2,TBPL1,PQBP1,RUNX1,NFKBIB,RFXAP |
| 2.829e-04 | -8.17 | PID_MYC_ACTIV_PATHWAY | MSigDB lists | PID_MYC_ACTIV_PATHWAY | 79 | 22 | 17758 | 2279 |
LIN28B,DDX18,NDUFAF2,CDK4,SLC2A1,MINA,LDHA,ID2,ODC1,UBTF,SMAD3,CAD,POLR3D,TRRAP,IREB2,PMAIP1,MYC,EIF2S1,GPAM,TAF12,PEG10,BMI1 |
| 2.831e-04 | -8.17 | - | gene3d domains | 1.10.287.10 | 6 | 5 | 9988 | 1398 |
MARS,EPRS,GARS,HARS,WARS |
| 2.833e-04 | -8.17 | ribonucleoside monophosphate biosynthetic process | biological process | GO:0009156 | 73 | 21 | 16441 | 2138 |
AK2,PPAT,UPP1,ATP6V0A1,ADSL,APRT,CHCHD10,IMPDH2,ATP5D,STOML2,CAD,AMPD3,HPRT1,GART,ATP5G2,ATIC,SURF1,UMPS,CMPK1,ADK,PRPS1 |
| 2.834e-04 | -8.17 | GSE27786_LSK_VS_MONO_MAC_UP | MSigDB lists | GSE27786_LSK_VS_MONO_MAC_UP | 179 | 40 | 17758 | 2279 |
ZNF280C,SF3A3,SLC29A1,MLH1,RPAIN,KDM1A,EDC3,CD96,PUS3,ARHGAP18,ZSWIM7,TAF3,BANF1,FBXO31,SLC25A23,RPL22L1,DENND1A,SERBP1,IPO11,TSHZ1,CHD9,PDK1,CLYBL,TFPI,PACRGL,SCMH1,GUF1,NUP214,ZNF251,C1orf122,PRPF40B,PES1,RETSAT,LSS,FAM135A,TOM1L2,TP53BP1,EXOC4,PPIL3,SLC43A1 |
| 2.838e-04 | -8.17 | histone H2B ubiquitination | biological process | GO:0033523 | 9 | 6 | 16441 | 2138 |
CTR9,PAF1,RNF40,CDC73,UBE2E1,WAC |
| 2.855e-04 | -8.16 | lysine N-methyltransferase activity | molecular function | GO:0016278 | 53 | 17 | 16491 | 2164 |
ASH1L,KMT2D,SETD1B,KMT2E,SETD2,EHMT1,SETD7,MEN1,KMT2C,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,SETD6,KMT2A,SMYD3 |
| 2.855e-04 | -8.16 | protein-lysine N-methyltransferase activity | molecular function | GO:0016279 | 53 | 17 | 16491 | 2164 |
ASH1L,KMT2D,SETD1B,KMT2E,SETD2,EHMT1,SETD7,MEN1,KMT2C,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,SETD6,KMT2A,SMYD3 |
| 2.857e-04 | -8.16 | HGTP_anticodon | pfam domains | PF03129 | 9 | 6 | 16629 | 2165 |
HARS2,EPRS,GARS,HARS,POLG2,TARS |
| 2.860e-04 | -8.16 | GCM_DFFA | MSigDB lists | GCM_DFFA | 122 | 30 | 17758 | 2279 |
KDM3B,EPM2AIP1,ANKRD17,BAZ2A,HECTD3,MARCH6,ARID1A,C1orf52,IKBKAP,TRAPPC6B,FAM8A1,POGZ,ZNF655,TAF9B,ZFP62,COMMD9,KPNA3,NUP133,HNRNPR,HNRNPH3,LEMD3,VPS52,ASB3,RAN,RBPJ,CELF1,ZMYM2,MTMR1,DMTF1,SMG1 |
| 2.866e-04 | -8.16 | THF_DHG_CYH_C | pfam domains | PF02882 | 4 | 4 | 16629 | 2165 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.866e-04 | -8.16 | THF_DHG_CYH | pfam domains | PF00763 | 4 | 4 | 16629 | 2165 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.866e-04 | -8.16 | tRNA-synt_1b | pfam domains | PF00579 | 4 | 4 | 16629 | 2165 |
WARS2,YARS,YARS2,WARS |
| 2.886e-04 | -8.15 | macromolecular complex binding | molecular function | GO:0044877 | 1394 | 226 | 16491 | 2164 |
POLB,CGN,ATRX,KIF5A,MFGE8,SIRT2,GIT2,SKI,SMARCB1,DST,ABL2,RAP1A,MYH3,RELB,ZEB1,RAN,PCOLCE2,HRG,MEIS3,SLC27A5,TIMM50,FLNC,NRAS,SIRT6,PPARG,LIMA1,CDK4,KATNAL1,HSPA5,EYA3,NFIA,KIF15,GMFB,CUX1,PSMG1,WDHD1,CAMSAP2,CXADR,ARPC3,CHAF1A,PEX1,KIF16B,GNAI1,DDX3X,PAF1,UBTF,SKIL,TCF7L1,RAD18,GATA6,CCNT1,PER1,EEFSEC,PQBP1,ADAM9,DLX2,BEND6,TXN2,NMD3,MEF2C,TNNC1,RELL2,TTN,FN1,FOXO1,PRPF31,ANKRD17,KHDRBS1,SIRT7,SMAD7,CENPB,BARX2,ZIC2,EVPL,CDC73,CHD5,CD226,TOX4,SH2B3,RNF40,FKBP1A,P3H1,CEP290,MCM5,MBD2,MYC,ZNF326,VAPB,CTR9,MFAP2,NOC3L,PRMT5,ATP6V0D1,KLRD1,GATAD2B,STAG1,MYO10,POLA1,ELP3,RAP1B,SMARCD3,EIF2A,ARID1A,SUPT5H,TRIM37,ABCF1,TCF7L2,PHF6,IRS1,ATXN7,NSF,FSCN1,CDK9,SRP68,MB21D2,SMYD3,ID1,ASH1L,PAFAH1B1,ACTR3,MYO7A,TNXB,DDR2,OLA1,PPP2R2A,SMARCA4,MYH9,RIPK1,FOSL2,CORO6,PPP1R9A,RPAIN,PELP1,RING1,SBDS,KDM1A,CHD7,SHC1,CAMTA2,NVL,ERI1,FMNL1,UCHL5,WAC,MMP14,RNF2,ETF1,SSBP1,CORO1A,SERPINH1,KMT2A,BRD4,SSFA2,MTIF2,C1QTNF1,GRHL3,DLG4,MRRF,POU2F1,ATXN1,VIM,SATB2,SETD7,FGFR1,SNCA,PES1,TAF2,HLA-DMA,SMAD3,DNTTIP1,RANBP2,SMARCC1,ELP2,ADNP,ITGA2,SCARB1,MUTYH,LAMA5,MID1,MAPT,HMGA2,DNAJC2,TCF3,AGO2,MAP1S,KIF5C,MLH1,IKBKAP,PSMF1,FOXO3,ANKRD54,IQGAP2,PTPN2,POLR3D,SACS,NEBL,ANXA7,NISCH,SHMT2,CD44,DMRT1,HSD17B12,TOP1,KDM6B,PPP1R9B,PXN,APEX1,KDM5A,APTX,GPNMB,MEN1,POLR3A,RERE,RPA1,NSD1,BCAS3,EIF2S1,SVIL,ATM,RBPJ,MBD6,PGAM5,IGBP1,KIF1B,CORO2B,KAT6A |
| 2.900e-04 | -8.15 | ACCAAAG,MIR-9 | MSigDB lists | ACCAAAG,MIR-9 | 479 | 88 | 17758 | 2279 |
CUL4A,LIN28B,TNFRSF21,RBFOX2,PDK4,TMEM109,KLHL18,MYH9,ADAMTS6,RNF24,SYNJ1,STAM,AMBRA1,PCDH7,NRF1,SHC1,IKZF5,ZKSCAN1,TBC1D22A,RNF111,BCAP29,DENND1A,CARM1,TBC1D8,PHLDB2,AEBP2,BRD4,PTBP2,ANK2,MRRF,MARCH6,ATP8B2,SON,SLC50A1,GZF1,DYRK1B,SLC39A14,RANBP2,SLC30A3,IKZF4,INSIG1,HLCS,SIX5,CC2D1B,HIC2,NFASC,LPP,TMCC1,HMGA2,NCOR2,DNAJA4,AUH,JUP,RHOBTB1,ARFIP2,IGF2BP2,CSNK1A1,FOXP1,CDC73,ARID1B,MBNL1,NEDD4,IGF2BP3,SH2B3,SACS,ENTPD5,ZNF354A,HARS2,FBXL19,PCSK6,CAMKK2,CRIM1,ZNF654,KCNMA1,ARHGAP39,PRDM1,ARID1A,ZNF655,UBAP2,MTHFD2,STX1A,ARID3B,TBPL1,GPAM,FNBP1L,MMP16,C18orf25,IPO4 |
| 2.914e-04 | -8.14 | NSA2 (NSA2 ribosome biogenesis homolog) | protein interactions | 10412 | 41 | 15 | 16036 | 2270 |
PES1,NIFK,EIF2S2,LIN28B,DDX24,DDX18,SIRT7,RNF2,NLE1,FTSJ3,ZC3H3,PABPC4,PUM3,NOP56,ZNF646 |
| 2.919e-04 | -8.14 | POLR1E (polymerase (RNA) I polypeptide E) | protein interactions | 64425 | 25 | 11 | 16036 | 2270 |
UBTF,RRN3,DDX18,POLR1A,SMARCAD1,RNF2,POLR1B,POLR1C,NFKBIB,CPSF3,NOP58 |
| 2.934e-04 | -8.13 | transcription factor complex | cellular component | GO:0005667 | 297 | 59 | 17570 | 2233 |
TCF12,ASCC1,NPAS2,TAF1,TCF3,SMAD7,HES6,PBX1,BARX2,MED18,ATF7IP,SNAPC4,MGA,KDM1A,SKI,TADA3,SNW1,SUB1,ZFHX3,TAF3,GTF2H1,ZEB1,GTF3C3,PKNOX1,CARM1,ARNTL2,GTF2H3,DEAF1,ATF4,PPARG,NR6A1,CDK4,MED27,EYA3,MINA,SATB2,SOX4,TCF7L2,TAF9B,VDR,TAF2,SMAD3,TCF7L1,TRRAP,GTF2A1,GATA6,PDLIM1,HIF1A,E2F4,HIPK2,KLF4,ARNTL,TAF4,TBPL1,PUS1,RBPJ,TAF12,NCOR1,DDIT3 |
| 2.958e-04 | -8.13 | methenyltetrahydrofolate cyclohydrolase activity | molecular function | GO:0004477 | 4 | 4 | 16491 | 2164 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.958e-04 | -8.13 | formate-tetrahydrofolate ligase activity | molecular function | GO:0004329 | 4 | 4 | 16491 | 2164 |
MTHFD1L,MTHFD2,MTHFD2L,MTHFD1 |
| 2.958e-04 | -8.13 | methylenetetrahydrofolate dehydrogenase (NADP+) activity | molecular function | GO:0004488 | 4 | 4 | 16491 | 2164 |
MTHFD2,MTHFD1L,MTHFD2L,MTHFD1 |
| 2.962e-04 | -8.12 | AGGTGCA,MIR-500 | MSigDB lists | AGGTGCA,MIR-500 | 95 | 25 | 17758 | 2279 |
GPM6A,ADAMTSL3,ABCC4,CELSR3,CUX1,MYNN,BTBD11,PRKCE,DDX3X,RNF40,ANKRD13A,NRF1,CACNB1,PDZD2,KPNA3,SEC24C,ZNF236,DCTN4,PDS5B,NBEA,PURB,SLC4A7,ZRANB2,PPP3CC,SLC25A26 |
| 2.970e-04 | -8.12 | V$RORA1_01 | MSigDB lists | V$RORA1_01 | 233 | 49 | 17758 | 2279 |
ATP6V1A,NPAS2,KIF5A,GTF2IRD1,ZFP36L1,FAM122B,IP6K2,BZW2,PITPNM1,IL17RE,NAV1,PHF5A,CACNB2,CHD2,ITGAX,SPTAN1,MYB,KDM3B,MSI2,DTNB,FGF9,MPP6,CAMKK2,AOC2,JMJD1C,KIAA0586,SCMH1,SEMA3F,SHISA5,R3HDM2,ATP8B2,ONECUT2,ACOXL,RAD54B,YTHDF2,SPAG9,TRAP1,ABHD3,ARNTL,SOCS4,LARGE,HOXA3,SLC4A7,EME1,NRP1,NR2F2,SPOCK2,TNRC6A,MEF2C |
| 2.982e-04 | -8.12 | Resolution of D-Loop Structures | REACTOME pathways | R-HSA-5693537 | 34 | 13 | 8202 | 1117 |
EXO1,RBBP8,BRCA2,SLX4,PALB2,XRCC2,RAD51B,TOP3A,ATM,BRCA1,EME1,RMI1,SPIDR |
| 2.982e-04 | -8.12 | CACTTTG,MIR-520G,MIR-520H | MSigDB lists | CACTTTG,MIR-520G,MIR-520H | 227 | 48 | 17758 | 2279 |
TBKBP1,TTN,FOXO1,CELSR3,NPAS2,KHDRBS1,SMAD7,TNKS1BP1,GBF1,SKI,DNAJB6,JAZF1,SOCS6,NBEA,PRICKLE2,ETF1,IGF2BP1,CMPK1,MAP3K14,ERI3,DBN1,CHD9,TRIM13,SSFA2,ATXN1,SATB2,MEF2D,ENC1,PLCB1,MAT2A,SLC39A14,ZFAND3,SLC30A3,KPNA1,KPNA3,SERINC1,HIF1A,LUC7L3,SET,TBX3,CSMD3,GREB1L,RUNX1,TBL1X,DMTF1,MIPOL1,PRKAR2A,TNRC6A |
| 2.984e-04 | -8.12 | ATGCTGC,MIR-103,MIR-107 | MSigDB lists | ATGCTGC,MIR-103,MIR-107 | 209 | 45 | 17758 | 2279 |
HERC2,TBKBP1,CHST11,AK2,NF1,ZHX3,KIF5A,PDE4B,SPATS2L,SYNJ1,MBNL1,ZMYM2,CDK6,CARM1,MYB,VOPP1,BDNF,RBCK1,ADAMTSL3,FGF2,BAZ2A,GPCPD1,USP42,NFIA,DLG4,PCNXL2,RSBN1,SATB2,PNN,MEF2D,PPIP5K2,RAB10,DCBLD2,UBAP2,KPNA1,LRP1B,SUFU,CC2D1B,ITGA2,HIC2,PURB,GREB1L,FNBP1L,BLMH,TSPAN5 |
| 2.994e-04 | -8.11 | negative regulation of nucleic acid-templated transcription | biological process | GO:1903507 | 1206 | 197 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,PTPRK,DEAF1,HMBOX1,RBCK1,AEBP2,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,PAF1,UBTF,SKIL,TCF7L1,SUPT4H1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,BARX2,ZIC2,RSF1,CDC73,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,PRMT5,NRIP1,MYB,ZNF675,GATAD2B,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,MYBBP1A,EHMT2,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,CYLD,MAP2K5,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,ZBTB21,PPID,DNAJB6,RNF2,CASP8AP2,SAP30,MOSPD1,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,TCF3,H2AFJ,NFX1,ID2,ATF7IP,GAS6,TRIM22,BHLHE40,RPS6KA5,FOXP1,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,YBX3,DMRT1,SOX6,FGF9,MSX1,APEX1,KDM5B,PSPC1,FOXN3,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,DKK1,MKX,RERE,TRIB3,NSD1,TBX3,SET,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 2.996e-04 | -8.11 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 162 | 37 | 17758 | 2279 |
ID1,CCDC58,SLC2A1,MAB21L3,PLA2G12A,BHLHE40,FOXO3,HSPA1A,DDIT4,CAD,NAV1,S100A10,PMAIP1,MYC,SLC39A7,SRRM2,CDK6,PERP,SESN2,NR6A1,ARRDC3,LDHA,HSPA1B,DCXR,VCAN,FAT1,TIMM17A,TBX3,EXOC4,HK2,AEN,PFDN2,ZAK,ZMAT3,PTPN14,CPT1C,LPP |
| 2.996e-04 | -8.11 | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN | 162 | 37 | 17758 | 2279 |
PCNT,PAFAH1B1,CSNK2A1,KIF5C,OPA1,REEP5,MGA,NDUFB3,ATIC,RAPGEFL1,TTC3,MGLL,PPA1,SERBP1,TOP1,DDN,DEAF1,CAMKK2,COL5A2,RB1CC1,HSPA5,MARS,DENND4A,ECH1,SEC31A,RANBP2,KIDINS220,COPS5,CUL2,ORC5,MPV17,PFDN2,EIF2B3,ZMAT3,KIF1B,MAP2K4,USP15 |
| 2.997e-04 | -8.11 | MDFIC (MyoD family inhibitor domain containing) | protein interactions | 29969 | 6 | 5 | 16036 | 2270 |
CSNK2A1,RPS6KA5,CCNT1,CDK9,SOCS4 |
| 3.003e-04 | -8.11 | carboxylic acid metabolic process | biological process | GO:0019752 | 864 | 147 | 16441 | 2138 |
GGT1,RARS2,PRKAB2,AARS2,SLC25A21,PLOD1,SLC6A8,AARS,AHCYL2,LPIN1,PCYOX1L,FAAH2,PPCDC,SUCLG2,ME1,SLC27A5,YARS,PPM1K,MPST,ACADS,SESN2,ATF4,PPARG,HARS,ALDH1L2,BRCA1,MTHFD1L,DLST,ODC1,MPC1,PYCR1,GLS,MSRA,DDAH2,HLCS,BDH2,TNFRSF1A,ABCC3,RBP1,SEPHS2,XYLB,CARS,SARS,LARS2,ST6GAL1,HSD17B10,PLA2G12A,PHGDH,ETFB,YARS2,ATIC,ALDH18A1,PPA1,MTHFD1,FADS1,WARS2,PPAT,ELOVL6,PCCA,RDH10,IDH3G,TBXAS1,CPT1A,ACOXL,MTR,PGD,DAGLA,EPRS,MTHFD2,GSTO2,HIF1A,VCAN,D2HGDH,HK2,SLC16A1,DPEP1,DTD1,PEX13,GGT7,CNDP2,CPT1C,SDSL,SUCLG1,SLC2A1,UROD,PDK4,TNXB,LPCAT3,CAD,FARSA,DECR1,ASNS,CBR4,PYCRL,LPIN2,HIBCH,AHCYL1,MTHFD2L,MGLL,TMLHE,ACSL5,MCEE,NARS2,GARS,PDK1,NARS,SLC35D1,HSD3B7,WARS,SNCA,DCXR,PEMT,ATG7,MORC2,DMGDH,SERINC5,BCKDK,AUH,MRI1,FARS2,VARS,LIAS,PEX7,GART,GATC,ACOT11,HARS2,SHMT2,PTGS1,PHYKPL,HSD17B12,LYPLA2,PFKFB4,PSAT1,LDHA,MARS,MMAA,TARS,ECH1,SLC23A2,RARS,ETFDH,SERINC1,DAGLB,ACOX1,GPAM,GCSH |
| 3.053e-04 | -8.09 | histone-lysine N-methyltransferase activity | molecular function | GO:0018024 | 44 | 15 | 16491 | 2164 |
NSD1,ASH1L,KMT2D,SETD1B,SUV39H2,EHMT2,KMT2E,SETD2,EHMT1,SETD7,MEN1,KMT2C,KMT2A,SMYD3,DOT1L |
| 3.076e-04 | -8.09 | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP | 168 | 38 | 17758 | 2279 |
PTP4A1,PHF3,FAM208B,BRAF,FEM1C,ITPRIP,PDE4B,ZFP36L1,NECAP1,ZNF709,IP6K2,FOSL2,BHLHE40,NAMPT,LONRF2,ZNF326,ETF1,CNTNAP3B,TLCD1,ZNF234,PTBP2,DDX24,TLE3,USP42,JMJD1C,RANGAP1,MEF2D,MARCH6,USP36,GZF1,ZC3H12A,HIF1A,L3MBTL3,ZNF236,ARNTL,CSRNP1,BEND6,DHCR7 |
| 3.076e-04 | -8.09 | positive regulation of nitrogen compound metabolic process | biological process | GO:0051173 | 1781 | 279 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,PRKCA,GABPB2,LPIN1,NOS1AP,SKI,GIPR,SREBF2,ZFHX3,WIZ,RNF111,ZNF148,MEIS3,DDN,HMBOX1,NR6A1,GNL3,EYA3,NFIA,TCEB3,CUX1,AKAP12,SUPT20H,STOML2,DDX3X,DDAH2,BRCA2,SUPT4H1,CCNT1,RUNX1,RFXAP,P2RY11,MEF2C,BANP,EGR1,JUP,KHDRBS1,SIRT7,PID1,RSF1,CDC73,RBM20,ENTPD5,APLF,MYC,MED24,PABPC1,TERF2,MYB,GTF2H3,BDNF,WDR61,STAG1,RREB1,PRDM16,ARID5B,SMARCD3,ARID1A,NELFA,PLCB1,TRIM37,ONECUT2,ABCF1,CAT,TASP1,HIF1A,CDK9,SPEN,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SLX4,SHC1,ACD,WAC,LPIN2,KMT2A,KMT2D,BRD4,SATB2,MED16,MEF2D,SETD7,ERC1,SERP1,VDR,TAF2,SMARCC1,HIPK2,H2AFX,RPS6KB1,BRCC3,HMGA2,INSIG2,TCF3,ID2,TRIM22,RPS6KA5,FOXO3,MAD2L2,SFR1,TADA3,SNW1,TRIAP1,YBX3,LARP4B,SAMD4A,SOX6,MBTPS2,SLC40A1,APEX1,IL6R,KLF6,GUF1,FOXC1,UBC,POLR2A,NSD1,ARID3B,BMP4,IGBP1,UQCC1,DDIT3,KAT6A,TRIM16,ATRX,NF1,KMT2E,GPBP1L1,AAMDC,PPARGC1B,SIRT2,HNRNPLL,MAP2K3,SMARCB1,PHF5A,DHX33,ZEB1,RELB,RAN,ETV1,TRIM14,ZBTB17,DEAF1,TRIM13,ATF4,RBCK1,PPARG,CDK4,HSPA5,BRCA1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,TCF7L1,HPRT1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,TNFRSF1A,DLX2,CLU,ZC3H8,UQCC2,FOXO1,TAF1,PAX2,SMAD7,TRIM15,ZIC2,BARX2,RLF,ARID1B,NAMPT,ELL,SUB1,CEP290,BUD31,CTR9,VAPB,GTF2H1,ICE2,NRIP1,CAMKK2,PAXBP1,UTP15,EIF2A,SUPT5H,TCF7L2,ATXN7,IRAK2,ZFP90,TBL1X,TESC,TCF12,ASH1L,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,NRF1,RRN3,JAG1,BRE,CAMTA2,NVL,IKBKB,MET,SPIDR,CTC1,MAML3,PRPF19,MOSPD1,KAT8,DDX41,GRHL3,ATXN1,DKC1,SMAD3,IKZF4,ADNP,SIX5,KLF4,COPS5,CEBPZ,ARNTL,PUS1,HEATR1,PKIB,DNAJC2,MAP3K13,SUPT6H,CAMK1,AGO2,ATF7IP,BMP6,PRKCH,HAS3,TMEM161A,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,FGF2,ZNF821,KDM5A,SMARCAD1,MEN1,HSPA1B,RERE,TBX3,TAF4,BCAS3,CSRNP1,NCBP2,MYRF,TAF12,RBPJ,NR2F2,NFKBIB,HRH1 |
| 3.078e-04 | -8.09 | POLR3C (polymerase (RNA) III (DNA directed) polypeptide C (62kD)) | protein interactions | 10623 | 37 | 14 | 16036 | 2270 |
SUB1,POLR3D,POLR1A,POLR3E,CRCP,SMARCA4,RSL1D1,RANGAP1,GTF3C3,CEP63,POLR3B,POLR1C,POLR3A,POLR3G |
| 3.085e-04 | -8.08 | histone monoubiquitination | biological process | GO:0010390 | 23 | 10 | 16441 | 2138 |
PAF1,RNF40,WAC,CTR9,RNF2,BCOR,TRIM37,CDC73,RING1,UBE2E1 |
| 3.101e-04 | -8.08 | STIP1 (stress-induced phosphoprotein 1) | protein interactions | 10963 | 122 | 32 | 16036 | 2270 |
CUL7,FN1,TRIP6,HSD17B10,MAP1S,PHGDH,HSPA1A,AMBRA1,SRSF2,ACD,COPS4,PPID,DNAJB6,RDX,ME1,AHCYL1,PPA1,CDC37,MSI2,ITPA,USP49,HSPA5,SUMO3,POU2F1,KCNH2,HSPA1B,NME1-NME2,AHNAK,HNRNPH3,CDK9,FKBP5,IGBP1 |
| 3.153e-04 | -8.06 | negative regulation of RNA biosynthetic process | biological process | GO:1902679 | 1221 | 199 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,PAF1,UBTF,SKIL,TCF7L1,SUPT4H1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,BARX2,ZIC2,RSF1,CDC73,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,PRMT5,NRIP1,MYB,GATAD2B,ZNF675,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,MYBBP1A,EHMT2,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,CYLD,MAP2K5,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,ZBTB21,PPID,DNAJB6,RNF2,CASP8AP2,SAP30,MOSPD1,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,TCF3,H2AFJ,NFX1,ID2,ATF7IP,GAS6,TRIM22,BHLHE40,RPS6KA5,FOXP1,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,YBX3,DMRT1,SOX6,FGF9,MSX1,APEX1,KDM5B,PSPC1,FOXN3,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,DKK1,MKX,RERE,TRIB3,NSD1,TBX3,SET,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 3.153e-04 | -8.06 | SCARNA22 (small Cajal body-specific RNA 22) | protein interactions | 677770 | 117 | 31 | 16036 | 2270 |
DDX24,DDX18,GNL3,PSPC1,POLR1A,PLRG1,SMARCA4,RANGAP1,VIM,NOP58,HNRNPA3,NOP56,PES1,POP1,MPHOSPH10,NOL10,DDX50,MYBBP1A,SYNCRIP,DHX37,HNRNPR,DDX31,FUS,NOLC1,PDCD11,GPATCH4,HNRNPM,TOP1,PRPF19,TMPO,SF3A1 |
| 3.154e-04 | -8.06 | BRIGHT | smart domains | SM00501 | 15 | 8 | 9131 | 1249 |
KDM5B,ARID2,ARID3B,KDM5A,ARID5B,KDM5C,ARID1A,ARID1B |
| 3.160e-04 | -8.06 | testis | COSMIC cancer mutations | testis | 761 | 130 | 17775 | 2278 |
PTPRA,TRPM6,MKS1,CSNK2A1,STK33,PRKCA,UBR5,MAP2K3,RTN1,ABL2,ANAPC1,SRSF2,SREBF2,NEK6,ATG3,XRCC2,SRRM2,CDK6,LONP1,PRKACB,SRPK2,TNK2,NRAS,ALDH1L2,CDK4,ANK2,NOL8,TFPI,AP4B1,NOL6,KSR2,LAMA2,SGK2,SON,CHAF1A,DYRK1B,TRRAP,SGSM2,CSMD3,RIOK1,TSEN2,WDR66,SEC24D,TAF1,CLK1,TRIO,PIK3R4,TGFBR2,PRKCE,SIPA1L3,ASAP1,SCAF1,PDE10A,MAP3K12,PABPC1,SIK3,CAMKK2,OBSCN,C19orf70,MTR,DYNC1H1,KIDINS220,ZZEF1,SNAP23,RIOK3,GPN1,TBCK,MAP2K4,CHMP2A,UPK3B,BIRC6,URB2,PDK4,DDR2,RIPK1,SMARCA4,RIOK2,FLAD1,VPS18,PRKD3,ANKRD13A,BRE,CCDC50,RPS6KL1,IKBKB,ADCK4,MET,CDK12,ZCCHC14,BRD4,PDK1,SFSWAP,TBC1D16,STK10,FGFR1,TJAP1,CAMK2D,HIPK2,RPS6KB1,MDN1,PDCD11,SMG1,SSH2,BCKDK,TNIK,BRAF,SULT1C2,SUPT6H,MAP3K13,CAMK1,ATG2B,CSNK1A1,FAM49A,FOXO3,PRKCH,ABL1,PVRL3,CLK2,RPS6KB2,TEX14,NAALADL2,OXSR1,TRIB3,TMEM237,SRD5A3,ATM,RPS6KC1,ZAK,KIF1B,STK4 |
| 3.161e-04 | -8.06 | WANG_TARGETS_OF_MLL_CBP_FUSION_DN | MSigDB lists | WANG_TARGETS_OF_MLL_CBP_FUSION_DN | 45 | 15 | 17758 | 2279 |
CAT,CUL4A,TTC27,HARS,G6PD,TRIAP1,CPOX,TMEM109,MINA,NRP1,AMOT,FTSJ3,NMD3,NIPSNAP1,OSBPL1A |
| 3.173e-04 | -8.06 | parathyroid | COSMIC cancer mutations | parathyroid | 494 | 90 | 17775 | 2278 |
MPI,FEZ2,PCNT,SLC5A5,TNFRSF21,GPR143,NAT10,MKS1,ARSJ,SEC16A,TNKS1BP1,HNRNPA3,BIRC2,FLNB,IGSF1,PDE3A,ECM1,CAMTA2,YLPM1,ANKRD11,ZEB1,TTC3,CMPK1,TRMT12,IPO11,LYST,TBC1D8,VPS13B,SF3A1,TMEM200A,ZCCHC14,GPM6A,NRAS,MANBAL,HSPA5,NLN,TOR1AIP2,CA5B,KCNH2,CHAF1A,ARMC4,BRCA2,TP53BP1,ZNF557,G6PD,ALKBH1,VPS13D,NFRKB,USP11,PTPN14,DMGDH,BRAF,XRRA1,MAPK8IP3,KIF5C,SLC25A12,CDC73,ZNF354A,LRP2BP,DDX31,DYNC2H1,CCDC88C,ZCCHC7,MICAL3,HNRNPM,SOX6,NT5E,HBG2,CAMKK2,CRIM1,ELP3,ARID5B,OBSCN,FAM126B,ZNF467,MEN1,KISS1R,CAT,EPRS,ATAD5,TMEM237,SYNCRIP,FAT1,ZZEF1,VPS37B,DNAH17,RIOK3,RBM26,BRWD3,MMP16 |
| 3.187e-04 | -8.05 | positive regulation of nucleic acid-templated transcription | biological process | GO:1903508 | 1423 | 228 | 16441 | 2138 |
ZNF292,THOC5,TRIM16,AAMDC,GPBP1L1,KMT2E,ATRX,PPARGC1B,HLTF,CCNL2,SIRT2,GABPB2,LPIN1,MAP2K3,SKI,SMARCB1,PHF5A,SREBF2,ZFHX3,DHX33,RELB,ZEB1,RNF111,ZNF148,RAN,MEIS3,ETV1,TRIM14,DDN,ZBTB17,DEAF1,HMBOX1,TRIM13,RBCK1,ATF4,PPARG,NR6A1,GNL3,HSPA5,NFIA,CUX1,SUPT20H,BRCA1,SOX4,MLLT10,DDX3X,PAF1,DYRK1B,UBTF,TCF7L1,BRCA2,SUPT4H1,INSIG1,GATA6,TP53BP1,CCNT1,PER1,E2F4,MKL2,TNFRSF1A,CLU,RUNX1,DLX2,ZC3H8,RFXAP,MEF2C,BANP,FOXO1,EGR1,JUP,TAF1,PAX2,SIRT7,SMAD7,PID1,BARX2,TRIM15,ZIC2,RSF1,RLF,CDC73,ARID1B,NAMPT,ELL,SUB1,CEP290,MYC,BUD31,GTF2H1,MED24,CTR9,ICE2,NRIP1,MYB,BDNF,CAMKK2,WDR61,PAXBP1,STAG1,RREB1,PRDM16,ARID5B,UTP15,SMARCD3,EIF2A,ARID1A,SUPT5H,PLCB1,TRIM37,ONECUT2,TCF7L2,CAT,ATXN7,TASP1,HIF1A,CDK9,SPEN,IRAK2,ZFP90,TBL1X,SMYD3,TESC,TCF12,MAP2K5,ASH1L,ZNF516,TRERF1,NPAS2,DDR2,SMARCA4,PBX1,RIPK1,FOSL2,PELP1,HSPA1A,KDM1A,BLOC1S2,TERF2IP,RRN3,NRF1,JAG1,CAMTA2,IKBKB,WAC,LPIN2,MET,KMT2A,MOSPD1,MAML3,KAT8,KMT2D,BRD4,DDX41,GRHL3,ATXN1,SATB2,MED16,MEF2D,SETD7,ERC1,VDR,TAF2,SMAD3,SMARCC1,IKZF4,SIX5,COPS5,HIPK2,KLF4,CEBPZ,ARNTL,PUS1,HEATR1,HMGA2,DNAJC2,INSIG2,SUPT6H,MAP3K13,CAMK1,TCF3,AGO2,ID2,ATF7IP,TRIM22,RPS6KA5,BMP6,FOXO3,MAD2L2,SFR1,PRKCH,TADA3,SNW1,HAS3,TRIAP1,DMRT1,SOX6,PKNOX1,MBTPS2,KDM6B,ARNTL2,SLC40A1,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,IL6R,MEN1,KLF6,FOXC1,UBC,RERE,HSPA1B,NSD1,ARID3B,TBX3,TAF4,CSRNP1,BCAS3,MYRF,RBPJ,BMP4,TAF12,NFKBIB,NR2F2,IGBP1,DDIT3,KAT6A |
| 3.187e-04 | -8.05 | positive regulation of transcription, DNA-templated | biological process | GO:0045893 | 1423 | 228 | 16441 | 2138 |
ZNF292,THOC5,TRIM16,AAMDC,GPBP1L1,KMT2E,ATRX,PPARGC1B,HLTF,CCNL2,SIRT2,GABPB2,LPIN1,MAP2K3,SKI,SMARCB1,PHF5A,SREBF2,ZFHX3,DHX33,RELB,ZEB1,RNF111,ZNF148,RAN,MEIS3,ETV1,TRIM14,DDN,ZBTB17,DEAF1,HMBOX1,TRIM13,RBCK1,ATF4,PPARG,NR6A1,GNL3,HSPA5,NFIA,CUX1,SUPT20H,BRCA1,SOX4,MLLT10,DDX3X,PAF1,DYRK1B,UBTF,TCF7L1,BRCA2,SUPT4H1,INSIG1,GATA6,TP53BP1,CCNT1,PER1,E2F4,MKL2,TNFRSF1A,CLU,RUNX1,DLX2,ZC3H8,RFXAP,MEF2C,BANP,FOXO1,EGR1,JUP,TAF1,PAX2,SIRT7,SMAD7,PID1,BARX2,TRIM15,ZIC2,RSF1,RLF,CDC73,ARID1B,NAMPT,ELL,SUB1,CEP290,MYC,BUD31,GTF2H1,MED24,CTR9,ICE2,NRIP1,MYB,BDNF,CAMKK2,WDR61,PAXBP1,STAG1,RREB1,PRDM16,ARID5B,UTP15,SMARCD3,EIF2A,ARID1A,SUPT5H,PLCB1,TRIM37,ONECUT2,TCF7L2,CAT,ATXN7,TASP1,HIF1A,CDK9,SPEN,IRAK2,ZFP90,TBL1X,SMYD3,TESC,TCF12,MAP2K5,ASH1L,ZNF516,TRERF1,NPAS2,DDR2,SMARCA4,PBX1,RIPK1,FOSL2,PELP1,HSPA1A,KDM1A,BLOC1S2,TERF2IP,RRN3,NRF1,JAG1,CAMTA2,IKBKB,WAC,LPIN2,MET,KMT2A,MOSPD1,MAML3,KAT8,KMT2D,BRD4,DDX41,GRHL3,ATXN1,SATB2,MED16,MEF2D,SETD7,ERC1,VDR,TAF2,SMAD3,SMARCC1,IKZF4,SIX5,COPS5,HIPK2,KLF4,CEBPZ,ARNTL,PUS1,HEATR1,HMGA2,DNAJC2,INSIG2,SUPT6H,MAP3K13,CAMK1,TCF3,AGO2,ID2,ATF7IP,TRIM22,RPS6KA5,BMP6,FOXO3,MAD2L2,SFR1,PRKCH,TADA3,SNW1,HAS3,TRIAP1,DMRT1,SOX6,PKNOX1,MBTPS2,KDM6B,ARNTL2,SLC40A1,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,IL6R,MEN1,KLF6,FOXC1,UBC,RERE,HSPA1B,NSD1,ARID3B,TBX3,TAF4,CSRNP1,BCAS3,MYRF,RBPJ,BMP4,TAF12,NFKBIB,NR2F2,IGBP1,DDIT3,KAT6A |
| 3.214e-04 | -8.04 | SUPT5H (SPT5 homolog, DSIF elongation factor subunit) | protein interactions | 6829 | 107 | 29 | 16036 | 2270 |
DBN1,C9orf78,CUL7,FN1,SUPT6H,SIRT6,SIRT7,ZNF512B,CSNK2A1,RANGAP1,BRCA1,SUPT5H,SAP30BP,POLR2A,PAF1,SUB1,SUPT4H1,GART,CCNT1,CDK9,SEC24C,SET,H2AFX,CTR9,SHMT2,RNF2,PRMT5,CARM1,MAML3 |
| 3.218e-04 | -8.04 | UTP14A (UTP14A small subunit (SSU) processome component) | protein interactions | 10813 | 102 | 28 | 16036 | 2270 |
SNU13,DDX18,SIRT7,WDR18,NFIA,CSNK2A1,VIM,DKC1,PHGDH,PDCD5,NOP58,RSRC1,ARIH2,PUM3,NOP56,PES1,DLEU1,DDX56,MPHOSPH10,HNRNPH3,BUD31,CCDC85B,WDR33,NOLC1,SRRM2,FTSJ3,SF3A1,PRPF19 |
| 3.227e-04 | -8.04 | RUIZ_TNC_TARGETS_DN | MSigDB lists | RUIZ_TNC_TARGETS_DN | 134 | 32 | 17758 | 2279 |
MCM6,MCM10,TUBB6,DCTPP1,MCM5,STC2,MET,CD44,CAV2,POLR1E,PRPS1,TRIP13,NAV3,TMPO,PEA15,RFC4,GINS3,CRIM1,SLC38A1,NXN,CAV1,MCM2,DKC1,ODC1,DKK1,RAD54B,EXO1,SLC7A1,H2AFX,EIF2S1,TPM1,TMEM158 |
| 3.230e-04 | -8.04 | METHYLTRANSFERASE_ACTIVITY | MSigDB lists | METHYLTRANSFERASE_ACTIVITY | 36 | 13 | 17758 | 2279 |
METTL1,NSD1,GART,SUV39H2,RNMT,ATIC,PEMT,EHMT1,PCMT1,PRMT5,COQ3,GCSH,CARM1 |
| 3.236e-04 | -8.04 | NONO (non-POU domain containing, octamer-binding) | protein interactions | 4841 | 143 | 36 | 16036 | 2270 |
CUL7,FN1,SLK,SMARCA4,RNF43,HSPA1A,HNRNPA3,SMARCB1,YLPM1,NUP133,MYC,MAD1L1,DYNC2H1,ALDH18A1,SRRM2,ZNRD1,HNRNPM,TOP1,RPS6KB2,PMS1,SMARCAD1,PSPC1,ATP6V0A1,SON,POLR2A,CHAF1A,RPA1,POP1,SMARCC1,COPS5,CUL2,ORC5,H2AFX,ASB3,FUS,SYNPO |
| 3.248e-04 | -8.03 | NARS (asparaginyl-tRNA synthetase) | protein interactions | 4677 | 50 | 17 | 16036 | 2270 |
GARS,JUP,FN1,SIRT7,ATXN1,XPO7,AARS,UBC,ABL1,EPRS,RARS,SUV39H2,CUL2,DUSP19,PUS1,PRPS1,PRMT3 |
| 3.250e-04 | -8.03 | BCL7A (B-cell CLL/lymphoma 7A) | protein interactions | 605 | 18 | 9 | 16036 | 2270 |
DPF3,SMARCC1,DPF2,SMARCA4,SMARCD3,RELB,ARID1A,ARID1B,SMARCB1 |
| 3.272e-04 | -8.02 | rRNA metabolic process | biological process | GO:0016072 | 155 | 36 | 16441 | 2138 |
SART1,NIFK,DROSHA,UTP14A,SBDS,NOP56,MRPS11,METTL16,CHD7,DDX56,RPS16,MPHOSPH10,ERI1,EXOSC4,GEMIN4,ERI3,FBL,UTP4,FTSJ3,DIS3L2,WDR36,EXOSC2,SKIV2L2,NPM3,NOL8,NOL6,UTP15,WBSCR22,METTL15,DKC1,NOP58,PES1,SRFBP1,HEATR1,NOLC1,PDCD11 |
| 3.281e-04 | -8.02 | myelodysplastic-myeloproliferative_neoplasm-unclassifiable | COSMIC cancer mutations | myelodysplastic-myeloproliferative_neoplasm-unclassifiable | 112 | 28 | 17775 | 2278 |
ARHGAP26,HMGA2,BRAF,KMT2D,NRAS,DDX18,NF1,ATRX,KDM5A,CUX1,BCOR,KMT2C,PHF6,ABL1,ATXN7L1,SH2B3,PRPF40B,NSD1,SRSF2,SOCS1,ABCA12,HIPK2,MYC,RUNX1,MET,KMT2A,SRPK2,SF3A1 |
| 3.281e-04 | -8.02 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable | 112 | 28 | 17775 | 2278 |
ARHGAP26,HMGA2,BRAF,KMT2D,NRAS,DDX18,NF1,ATRX,KDM5A,CUX1,BCOR,KMT2C,PHF6,ABL1,ATXN7L1,SH2B3,PRPF40B,NSD1,SRSF2,SOCS1,ABCA12,HIPK2,MYC,RUNX1,MET,KMT2A,SRPK2,SF3A1 |
| 3.282e-04 | -8.02 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | 192 | 42 | 17758 | 2279 |
VMA21,AK2,EIF3C,SSR4,PHGDH,RSRC1,ATXN7L1,FARSA,IDI1,ATIC,CFDP1,ACOT11,MED24,BCAP29,NDUFA6,POLR1E,HMGCR,MTHFD1,RABEPK,DDN,NAA38,APEX1,HARS,EIF3J,CDK4,TYW1,LGALS1,VIM,KCNH3,SRA1,C8orf33,TARS,PGD,HPRT1,COPS5,EIF2S1,FNTB,PPP3CC,IFITM2,SRP14,CPT1C,RNF114 |
| 3.282e-04 | -8.02 | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP | 192 | 42 | 17758 | 2279 |
C9orf78,IFT57,LYRM4,SCAMP3,SUCLG1,DDX19A,TMEM109,HSD17B10,SF3A3,SMARCA4,HLTF,POP5,PRKCA,HDDC2,ADH5,CD96,MPHOSPH10,ASNS,ZNHIT6,MYC,ZDHHC6,MAD1L1,SUCLG2,JOSD1,PRPS1,SEH1L,PRPF19,RANBP6,DDX28,FBXW4,ZNF512B,SUMO3,CYB5B,ZNF91,TARS,ARIH2,MAT2A,EPRS,TOE1,POLR3E,ZNF32,SETD6 |
| 3.282e-04 | -8.02 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | 192 | 42 | 17758 | 2279 |
PTP4A1,C9orf78,ZNF516,MVK,SH2D3A,FOXO1,PRKAB2,RFX1,PTPRA,SMAD7,MED13L,LPCAT3,TRIM22,FLNB,ABCA7,ZNF239,MAD1L1,JOSD1,TTC3,FHIT,FGF9,FBXW4,AKAP8L,ATG9A,ATF7IP2,KCNH2,RHOT2,SAP30BP,ZC3H12A,ATXN7,TOE1,TSR1,RPL28,KIAA0355,PER1,SPEN,PQBP1,ATM,BRD9,XPO6,C7orf26,MTCH1 |
| 3.282e-04 | -8.02 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN | 192 | 42 | 17758 | 2279 |
RHOBTB1,PTPRA,XPO7,NUP160,INPP1,REEP5,ZNF37A,RRN3,NUP133,SYN2,CACNB2,CFDP1,IKBKB,SLC39A7,MYH15,FXN,VCL,CNOT4,PRPS1,MTHFD1,KDM3B,GCNT2,PRIM2,TFCP2,POLA1,IDH3G,SETD2,R3HDM1,SMARCD3,MARS,PRDM1,PTK2,RDH11,BAZ2B,AHNAK,MPV17,PPP1R12B,VPS13D,ABCC3,IFITM2,NRP1,NOLC1 |
| 3.284e-04 | -8.02 | LARS (leucyl-tRNA synthetase) | protein interactions | 51520 | 59 | 19 | 16036 | 2270 |
CARS,FN1,NARS,VARS,MARS,AARS,UBR4,CIAPIN1,ABL1,EPRS,RARS,ASNS,ETF1,ARHGAP1,FUS,SRP14,NMD3,RTFDC1,TMPO |
| 3.294e-04 | -8.02 | KPNA2 (karyopherin alpha 2 (RAG cohort 1, importin alpha 1)) | protein interactions | 3838 | 175 | 42 | 16036 | 2270 |
FEZ2,CUL7,DNAJA4,FN1,BTBD2,PRPF31,PLRG1,KLC4,SMARCA4,MLH1,CSNK1A1,UBR5,PRKD3,GART,CTNNBL1,COPS4,TAF3,MYC,TANK,RELB,RAN,TERF2,HN1,PRPF19,PMS1,RNMT,IDH3G,HOMER2,BRCA1,WARS,ZC3H12A,RANBP2,KPNA1,KPNA3,CHD3,COPS5,ARL4A,CDK9,GPN1,FUS,NFKBIB,DDIT3 |
| 3.297e-04 | -8.02 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | 488 | 89 | 17775 | 2278 |
DMXL2,MVK,DCP1B,SMARCA4,MYH9,PRKCA,UBR5,PDE3A,PCDH7,PCYOX1L,SMARCB1,BRE,SOCS1,ZFHX3,ACD,NSRP1,PHKA1,GRIN2C,SNTG2,ANAPC10,TTC3,CDK6,LYST,CEP128,GPM6A,NRAS,KMT2D,TFCP2,PTPRM,ANK2,ARHGEF10,KMT2C,DDX60,CRYBG3,EIF3H,TMEM132B,ZFAND3,MSRA,IQCH,ASTN2,EEFSEC,E2F4,HIPK2,CSMD3,SEMA3C,MDN1,SPOCK3,SMG1,CHMP4C,HERC2,XYLB,BRAF,ITFG1,SEMA3E,FOXO3,PIP4K2A,ANXA10,SLC39A11,PRKCE,RNF40,KIAA1958,USPL1,PMPCA,PRICKLE2,SNX29,SOX6,MTHFD1,KRT20,WDFY3,PEAR1,PLCB1,MBNL2,AGAP1,NAALADL2,VAC14,DAGLA,VPS13C,LRP1B,PXDN,HIF1A,ATM,DTD1,SORCS2,MACROD1,PDLIM5,MIPOL1,ARHGAP10,ANAPC4,ZSWIM6 |
| 3.308e-04 | -8.01 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 198 | 43 | 17758 | 2279 |
AK2,TRIP6,DDX18,RHOBTB1,ST6GAL1,SMARCA4,SPATS2L,TUBB6,BZW2,FLNB,NOP56,PTRF,PPFIBP1,TRMU,SLC39A7,TRIP13,SEH1L,SPTAN1,DDX24,HSPA5,TFPI,FERMT2,ARHGEF12,SOX4,DKC1,ISG15,TCF7L2,FGFR1,PLIN2,PES1,PWP1,EPRS,TRIB3,MYBBP1A,PXDN,POLE2,ARL4A,SLC16A1,PUS1,TBXA2R,NOLC1,TMEM158,GCSH |
| 3.311e-04 | -8.01 | negative regulation of nucleobase-containing compound metabolic process | biological process | GO:0045934 | 1389 | 223 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,PRKCA,UBR5,SKI,SRSF2,SREBF2,ZFHX3,YLPM1,JAZF1,GPR87,RELB,ZEB1,ZNF148,FNIP2,ZNF85,KDM5C,HCFC2,OGG1,TRIM14,PTPRK,DEAF1,HMBOX1,TRIM13,RBCK1,AEBP2,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,PAF1,UBTF,SKIL,TCF7L1,BRCA2,SUPT4H1,RAD18,SUFU,GATA6,CCNT1,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,PID1,BARX2,ZIC2,RSF1,CDC73,DDIT4,RNF40,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,PRMT5,NRIP1,PABPC1,TERF2,MYB,GATAD2B,ZNF675,PAXBP1,RREB1,PRDM16,ARID5B,EIF4A2,WWC1,PRDM1,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,NR2F1,TCF7L2,ZNF425,CAT,MYBBP1A,EHMT2,CDK9,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,CYLD,MAP2K5,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,TERF2IP,ZBTB21,ACD,PPID,DNAJB6,RNF2,CTC1,CASP8AP2,MOSPD1,SAP30,KAT8,PRAME,KMT2D,PTBP2,SFSWAP,POU2F1,ATXN1,SATB2,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,SETD6,YEATS2,HMGA2,DNAJC2,NOSTRIN,NCOR2,SHQ1,TCF3,H2AFJ,NFX1,ID2,ATF7IP,GAS6,TRIM22,MLH1,BHLHE40,RPS6KA5,FOXP1,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,YBX3,DMRT1,SOX6,FGF9,MSX1,APEX1,KDM5B,PSPC1,FOXN3,DHX34,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,ZRANB3,RERE,MKX,DKK1,TRIB3,NSD1,TBX3,SET,MSH3,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 3.335e-04 | -8.01 | TTGCACT,MIR-130A,MIR-301,MIR-130B | MSigDB lists | TTGCACT,MIR-130A,MIR-301,MIR-130B | 384 | 73 | 17758 | 2279 |
PTP4A1,SNX27,PHF3,CYLD,BIRC6,PAPD4,RBM33,ATRX,PAFAH1B1,PTPRG,LCLAT1,WNT2B,RTN1,PRKD3,KDM2A,SOCS6,NBEA,CMPK1,ZNF3,DENND1A,TBC1D8,ZCCHC14,CHD9,BAZ2A,PPARG,PTPRM,GPCPD1,ARRDC3,R3HDM1,ATXN1,SOX4,DCBLD2,MLLT10,YTHDF2,ARHGAP21,RBBP8,IKZF4,ABHD3,HOXA3,NRP1,CEP170,RAB30,TNRC6A,EFNB2,B4GALT5,FAM46B,NHS,TGFBR2,MBNL1,ARHGAP1,IGF2BP1,MAP3K14,CNOT4,MAP3K12,MYB,VPS37A,WDFY3,RAPGEF4,PHACTR2,ARHGEF12,SNAP25,PLCB1,NME7,GADD45A,PMEPA1,SPEN,TAF4,VPS37B,CNOT6,ARHGAP12,PSAP,MB21D2,NR2C2AP |
| 3.407e-04 | -7.98 | BENPORATH_CYCLING_GENES | MSigDB lists | BENPORATH_CYCLING_GENES | 620 | 109 | 17758 | 2279 |
DMXL2,PTP4A1,MYCBP2,FANCD2,NUP43,TMEM132A,NUP160,BIRC2,ZSCAN5A,SMARCB1,FLAD1,SHC1,ACD,DNAJB6,SLC38A2,PAK1IP1,SUCLG2,RAN,MET,VCL,TRIP13,CASP8AP2,HN1,TMPO,SAP30,RFC4,TUBA1A,ZNF414,AP4B1,TSN,NFIA,KIAA1586,ABCC2,EFHC1,PNN,AKAP13,BRCA1,DKC1,MCM2,DSP,SAP30BP,CHAF1A,EXO1,RBBP8,CDC16,RAD18,ARL4A,CFD,H2AFX,HSPB8,TRMT2A,RUNX1,DMTF1,MID1,LPP,AOC3,MCM6,INSIG2,FAM189B,VTA1,MRI1,FAN1,RCAN1,ATF7IP,GAS6,RMI1,POM121,ABCA7,FKBP1A,MCAM,INTS7,VPS72,MCM5,ACAP3,KDELC1,CTR9,ANP32B,TOMM34,PKNOX1,TOP1,HMGCR,GINS3,PRIM2,STAG1,KDM5B,POLA1,AOC2,TLE3,TRA2A,JMJD1C,ELP3,WBSCR22,KIAA0586,TOP3A,ZNFX1,RANGAP1,LENG8,KLF6,RERE,PWP1,MGAT2,CDH24,SYNCRIP,GADD45A,HIF1A,TTC38,BIVM,ZRANB2,GCSH |
| 3.454e-04 | -7.97 | positive regulation of RNA metabolic process | biological process | GO:0051254 | 1488 | 237 | 16441 | 2138 |
ZNF292,THOC5,TRIM16,AAMDC,GPBP1L1,KMT2E,ATRX,PPARGC1B,HLTF,CCNL2,SIRT2,HNRNPLL,GABPB2,LPIN1,MAP2K3,SKI,SMARCB1,PHF5A,SREBF2,ZFHX3,DHX33,RELB,ZEB1,RNF111,ZNF148,RAN,MEIS3,ETV1,TRIM14,DDN,ZBTB17,DEAF1,HMBOX1,TRIM13,RBCK1,ATF4,PPARG,NR6A1,GNL3,HSPA5,NFIA,TCEB3,CUX1,SUPT20H,BRCA1,SOX4,MLLT10,DDX3X,PAF1,DYRK1B,UBTF,TCF7L1,BRCA2,SUPT4H1,INSIG1,GATA6,TP53BP1,CCNT1,PER1,E2F4,MKL2,TNFRSF1A,CLU,RUNX1,DLX2,ZC3H8,RFXAP,MEF2C,BANP,FOXO1,EGR1,JUP,TAF1,PAX2,SIRT7,SMAD7,PID1,BARX2,ZIC2,TRIM15,RSF1,RLF,CDC73,ARID1B,NAMPT,RBM20,ELL,SUB1,CEP290,MYC,BUD31,GTF2H1,MED24,CTR9,ICE2,NRIP1,PABPC1,MYB,GTF2H3,BDNF,CAMKK2,WDR61,PAXBP1,STAG1,RREB1,PRDM16,ARID5B,UTP15,SMARCD3,EIF2A,ARID1A,SUPT5H,NELFA,PLCB1,TRIM37,ONECUT2,TCF7L2,CAT,ATXN7,TASP1,HIF1A,CDK9,SPEN,IRAK2,ZFP90,TBL1X,SMYD3,TESC,TCF12,MAP2K5,ASH1L,ZNF516,TRERF1,NPAS2,DDR2,SMARCA4,PBX1,RIPK1,FOSL2,PELP1,HSPA1A,KDM1A,BLOC1S2,TERF2IP,RRN3,NRF1,JAG1,CAMTA2,IKBKB,WAC,LPIN2,MET,KMT2A,MOSPD1,MAML3,PRPF19,KAT8,KMT2D,BRD4,DDX41,GRHL3,ATXN1,SATB2,MED16,MEF2D,SETD7,ERC1,VDR,TAF2,SMAD3,SMARCC1,IKZF4,SIX5,COPS5,HIPK2,KLF4,ARNTL,CEBPZ,PUS1,HEATR1,HMGA2,DNAJC2,INSIG2,SUPT6H,MAP3K13,CAMK1,TCF3,AGO2,ID2,ATF7IP,TRIM22,RPS6KA5,BMP6,FOXO3,MAD2L2,SFR1,PRKCH,TADA3,SNW1,HAS3,TRIAP1,DMRT1,SOX6,PKNOX1,MBTPS2,KDM6B,ARNTL2,SLC40A1,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,IL6R,MEN1,KLF6,FOXC1,UBC,POLR2A,RERE,HSPA1B,NSD1,ARID3B,TBX3,TAF4,CSRNP1,BCAS3,NCBP2,MYRF,RBPJ,TAF12,BMP4,NFKBIB,NR2F2,IGBP1,DDIT3,KAT6A |
| 3.473e-04 | -7.97 | cytoskeleton | cellular component | GO:0005856 | 1933 | 294 | 17570 | 2233 |
ARHGAP26,PTP4A1,MYCBP2,POLB,CGN,ACTG1,MKS1,TUBE1,ENAH,CSPP1,RAC3,SKI,NEK6,RASSF3,MAD1L1,SUCLG2,FNIP2,CEP135,CDK6,SPAG6,LIMA1,EYA3,KIF15,AKAP12,CAMSAP2,EFHC1,MCM2,DDX60,SAP30BP,TMSB4X,CLNS1A,SH3GL1,STOML2,GNAI1,DDAH2,AHNAK,BRCA2,RAD18,DNAH2,TPM1,NRP1,SYNPO,PTPN14,HERC2,TNNC1,IFT57,CDC42EP2,TRIP6,JUP,CCDC53,OPHN1,MTUS1,PRKCE,NAV1,SLC7A11,ALKBH8,PEA15,MYO10,RAP1GAP2,KIAA0586,PTPN12,ATAT1,MAP7D1,EVI5,ONECUT2,SRA1,IRS1,DYNC1H1,NME7,PDLIM1,CCDC85B,NCOR1,PDLIM5,RTTN,DNM3,RAB11FIP4,MAP2K5,BIRC6,PAFAH1B1,C16orf45,ACTR3,OLA1,MYH9,TUBB6,PLEK2,CORO6,HSPA1A,FLNB,RPGRIP1L,BLOC1S2,RMDN3,CEP63,PXK,LYST,CFAP221,KRT7,WDPCP,ARHGEF10,DLG4,PNN,DSP,TTC28,SERP1,SNCA,ARHGAP21,CDC16,MISP,DCXR,G6PD,DNAJA3,IFT140,MDN1,XRCC4,YEATS2,MID1,CEP170,MAPT,TRIM36,SSH2,NOSTRIN,ID2,KIF5C,IP6K2,CEP126,MBNL1,MAD2L2,TTLL11,TADA3,ABL1,NEBL,TMSB10,RDX,S100A14,DYNC2H1,ACTR3B,SPTAN1,NUDC,PXN,CEP83,VPS37A,TTLL5,APEX1,CEP295,ARHGAP39,CCDC113,PTK2,YIF1A,KLHL22,STX1A,SVIL,ATM,PTPN4,MYOM2,IGBP1,CORO2B,CUL7,KIF5A,SIRT2,BIRC2,DST,SRPRB,ABL2,XRCC2,NCKIPSD,MYH3,IPP,RELB,RAN,PRKACB,CEP128,DBN1,FLNC,ATF4,KATNAL1,ANK2,TMEM216,COTL1,BRCA1,TCTN1,BSN,KIF16B,CCDC28B,ARPC3,RHOU,MSRA,CHD3,CCDC146,RLTPR,PQBP1,TSEN2,C2CD5,DCTN3,TTN,PAX2,DPF2,SMAD7,SMG7,EVPL,DNAH1,SPIRE1,CEP164,ELL,CEP290,TIMELESS,CCDC124,AKAP11,ATP6V0D1,KRT20,IFT43,HAUS6,PSMA1,DNAH14,ATXN7,APBB3,SPAG9,BICD1,FSCN1,SDCCAG8,DNAH17,PPP1R12B,SLC16A1,CASS4,TBL1X,BRSK2,SH3PXD2A,FNBP1L,PRKAR2A,CYLD,ID1,PCNT,PSTPIP2,SLC2A1,MYO7A,TBCCD1,TNKS1BP1,RADIL,PIBF1,PPP1R9A,SBDS,VPS18,SNTG2,MYH15,CORO1A,VCL,HTRA2,PRPF19,PHLDB2,EVL,TUBA1A,VIM,ENC1,UBR4,ARMC4,IFT81,IKZF4,WDR73,ARC,SEPT5,PARD3,TNIK,KIZ,KLC4,PDE4B,MAP1S,IGF2BP2,CSNK1A1,SFI1,IQGAP2,IFIT5,DCTN4,SHMT2,FBXO31,TTC17,AMOT,MICAL3,PPP1R9B,DNMBP,GPHN,TPM4,FERMT2,RANGAP1,ARHGAP32,PALLD,PEAK1,SYMPK,TARS,HSPA1B,MFN2,WDR35,BCAS3,FNTB,USP20,PREPL,KIF1B |
| 3.499e-04 | -7.96 | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | MSigDB lists | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 259 | 53 | 17758 | 2279 |
COMMD10,SMAD7,LETMD1,MYH9,COBLL1,RIPK1,ENAH,ATF7IP,GIT2,EEA1,AHCYL2,DHX37,ASAP1,PMAIP1,NVL,LTN1,GSTA4,LARP4B,CD44,PXK,NRIP1,ADARB1,PHLDB2,KDM5B,TPM4,PTPN12,CAMSAP2,ODC1,KLF6,PEAK1,PIK3CB,DDX49,CRYBG3,CAT,DDX3X,CAMK2D,ADNP,UBAP1,PMEPA1,ACOX1,ZNF436,CSRNP1,LARGE,SQLE,SLC4A7,SEMA3C,RUNX1,TBL1X,TPM1,ZAK,KIF1B,SMG1,RBP1 |
| 3.512e-04 | -7.95 | nucleoside phosphate catabolic process | biological process | GO:1901292 | 69 | 20 | 16441 | 2138 |
PDE4A,ITPA,UPP1,PDE4B,PDE2A,NUDT15,PDE3B,PDE3A,PDE8B,CAT,DCTPP1,AMPD3,HPRT1,PDE10A,NT5C,NT5M,OGG1,PDE9A,MUTYH,NT5E |
| 3.515e-04 | -7.95 | NUP50 (nucleoporin 50kDa) | protein interactions | 10762 | 78 | 23 | 16036 | 2270 |
GARS,NARS,ARID2,GMFB,SMARCD3,WDHD1,IMPDH2,TTI1,IKBKAP,FLNB,SBDS,SPOP,RANBP2,KPNA1,ASNS,SLX4,UBAP2,KPNA3,TP53BP1,TAF4,RAN,PFDN2,SRPK2 |
| 3.515e-04 | -7.95 | PPM1G (protein phosphatase, Mg2+/Mn2+ dependent, 1G) | protein interactions | 5496 | 78 | 23 | 16036 | 2270 |
CARS,USP7,SARS,GARS,USP49,TLE3,SIRT7,PSMA1,JMJD6,XPO7,STAM,USP36,TERF2IP,TTC1,POP1,TPD52L2,H2AFX,HIRIP3,AHCYL1,TROVE2,TERF2,RPS6KB2,SRPK2 |
| 3.515e-04 | -7.95 | EIF4G1 (eukaryotic translation initiation factor 4 gamma, 1) | protein interactions | 1981 | 78 | 23 | 16036 | 2270 |
CUL7,FN1,SKIV2L2,SIRT7,EIF4A2,NAT10,SF3A3,USP10,BRCA1,TNKS1BP1,PABPC4,ISG15,PUM3,EIF3H,UBE3A,DCTN4,ANXA5,UPF2,NCBP2,FBL,PABPC1,HTRA2,SF3A1 |
| 3.524e-04 | -7.95 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | MSigDB lists | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | 96 | 25 | 17758 | 2279 |
GTF2H3,VPS37A,RNMT,TAF1,TCEB3,RANGAP1,NUP43,SUPT5H,NUP214,POM121,POLR2A,RANBP2,ELL,SUPT4H1,GTF2A1,NUP133,CCNT1,CDK9,VPS37B,TAF4,GTF2H1,NCBP2,RAN,TAF12,SEH1L |
| 3.524e-04 | -7.95 | KEGG_PYRIMIDINE_METABOLISM | MSigDB lists | KEGG_PYRIMIDINE_METABOLISM | 96 | 25 | 17758 | 2279 |
PRIM2,ITPA,POLA1,UPP1,POLR1A,POLR2A,POLR3A,POLR3G,CAD,POLR3D,NME1-NME2,ENTPD5,NME7,POLE2,UMPS,NT5C,POLR3B,CMPK1,POLR1B,POLE3,POLR1C,NT5M,ZNRD1,POLR1E,NT5E |
| 3.558e-04 | -7.94 | upper_aerodigestive_tract | COSMIC cancer mutations | upper_aerodigestive_tract | 13823 | 1834 | 17775 | 2278 |
ARHGAP26,PTP4A1,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,LPAR3,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,LETM2,MAD1L1,KDM5C,MSANTD2,SRRM2,FTSJ3,PPM1K,CCDC57,NRAS,LIMA1,UPP1,EHMT1,NFIA,KIF15,C5AR1,WDHD1,ABCC2,MCM2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,SSU72,RAD18,LRRC40,MPV17,DIRAS1,RIOK1,RUNX1,VASH2,ZNF532,BANP,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,WDR60,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,CCDC85B,BPNT1,KIAA0196,PDLIM5,SRP14,ARHGAP10,SGSM3,GALE,RAB11FIP4,PAFAH1B1,C16orf45,MAB21L3,DDR2,CD99L2,FAM122B,GRINA,NUP43,MCM9,RPGRIP1L,ZBED2,CD96,ESAM,ZSWIM7,ACD,TBC1D22A,SETD5,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,KIAA1549,DENND1A,LYST,PMS1,KMT2D,PI4KAP2,ZNF480,SLCO6A1,FAM171A2,PCNXL2,MEF2D,KCNH3,GSTCD,NUDT15,DSP,VPS53,MAT2A,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,NSMCE2,ARL13B,POLR3E,CAMKMT,RPS6KB1,CENPBD1,METTL2B,CEP170,CATSPERG,BAG1,MAPT,RAB30,MORC2,HMGA2,SHQ1,ATG2B,GAS6,TRIM22,IP6K2,RNASEH2B,PSMF1,TTLL11,SNW1,PSMG4,TAF3,CFDP1,UNC13A,ACOT11,LTN1,PTGS1,RAPGEFL1,ZNF710,FBXL19,C15orf41,SAMD4A,RPL22L1,PNMA1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,OXSR1,NSD1,SRCAP,HERC1,ACOX1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,MIOS,CDK4,ANK2,HSPA5,TSN,SUMO3,MARCKSL1,LAMA2,KCNH2,KRTCAP2,DLST,CRYBG3,CXADR,MLLT10,BSN,DYRK1B,HPRT1,TCF7L1,LSS,INSIG1,CHD3,ARL4A,E2F4,DPP4,ADAM9,PPP3CC,PRPF4,MAGI1,USP15,CTU2,FOXO1,CLK1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ZIC2,ARID1B,SPIRE1,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,VAPB,CTR9,PNPLA3,LRSAM1,SNX29,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,PTP4A2,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,ID1,OLFM2,PAPD4,UPK3B,ARID2,NDUFAF2,OSBPL9,NTSR1,LAGE3,RIPK1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,DDX60L,URB1,PLXNB1,FDX1,ANKRD13A,ZNF608,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,LMBR1L,KLF4,ATG7,INTS9,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,MCM10,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,HIST2H2AB,ANKRD54,ADH5,SURF2,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,ABCF2,KRTCAP3,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,NOL10,TAF4,TBX3,CSRNP1,BCAS3,FNTB,USP20,TMEM219,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRKCA,NBEAL1,LRP5L,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,CSGALNACT2,ZNF646,ACADS,GDAP1,FAM127A,OSBP2,EFHC1,ZDHHC14,DENND4A,SON,DDX60,CLNS1A,PLCXD2,GZF1,GNAI1,SPOP,OSBPL1A,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BMI1,RFXAP,SPOCK3,SPOCK2,ZMAT3,NMD3,CADM4,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,DPM3,PRPF39,SSR4,PDCD5,MTUS1,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,MFAP2,CNOT4,RTFDC1,FDFT1,EXOSC2,RREB1,PRIM2,ANAPC13,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,MTR,SLC26A11,ZNF850,PHF6,ATP9B,CAT,ASCC3,C6orf141,MTHFD2,ALKBH3,HIF1A,VCAN,SPEN,MED15,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,TMEM104,PLEK2,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NUBPL,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,SHF,TTC3,CMPK1,CDK12,CASP8AP2,SAP30,BRD4,GON4L,C1orf228,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,ZBTB25,BAZ1A,DNTTIP1,CAMK2D,SMARCC1,WDR5B,G6PD,LARGE,FTSJ1,IFT140,SLC4A7,CBWD1,TRAF3,TBXA2R,SETD6,XRCC4,MID1,SSH2,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,INPP1,GIGYF2,FAM8A1,ABL1,ATXN7L1,NEBL,ELP5,DYNC2H1,CELF1,S100A14,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,APEX1,ZFYVE1,AGPAT4,ADSL,PACS1,BMS1,KLF6,GUF1,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,EIF3C,ATRX,RARS2,PCYOX1L,DST,JAZF1,ANAPC11,SLC39A7,MYH3,GPATCH1,ZEB1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,SIRT6,ARRDC3,VWCE,TMEM216,KSR2,MTHFD1L,COTL1,PITPNB,SGK2,KMT2C,ST3GAL5,ARPC3,TIMM44,YTHDF2,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,CLU,EME1,ZC3H8,DCAF5,MTCH1,FBXO45,RHOBTB1,SCART1,ZCCHC8,VTA1,STXBP6,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,ISPD,CCDC124,ZCCHC7,PRF1,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,MSI2,ZNF234,PPAT,ELOVL6,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,MGAT2,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,TMEM117,CDKAL1,TBL1X,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,TCF12,DMXL2,SNX27,DLL4,FEZ2,PSTPIP2,TNXB,PIGH,SMARCA4,PBX1,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RAET1E,RRN3,MPHOSPH10,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,GNG5,C6orf89,AUP1,MAML3,NPW,PRAME,GRHL3,METTL2A,ATXN1,MRRF,METTL15,DKC1,EDEM2,UBR4,S100A16,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMCC1,DNAJC2,BCKDK,SUPT6H,CAMK1,ARL15,DYM,PDE4B,VPS45,IGF2BP2,ATF7IP,CHCHD10,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,LDLRAD3,FBL,ERI3,MICAL3,TOP1,RPS6KB2,MARCH9,KDM6B,SLC6A16,DNMBP,GPHN,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,WDR35,AGTPBP1,VPS37B,POLR1C,NFKBIB,ZSWIM6,GNB3,ASCC1,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,PABPC4,NOS1AP,AMBRA1,PCDH7,C1orf159,SREBF2,NEK6,SYN2,PMAIP1,RABGAP1L,RASSF3,FAAH2,PDS5B,WIZ,HRG,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,GNL3,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,TMSB4X,STOML2,DDX3X,BRCA2,SUPT4H1,TMEM139,FIP1L1,LPP,MEF2C,HERC2,CARS,EP400,TRIP6,KHDRBS1,SIRT7,PRAF2,NHS,PLA2G12A,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,EIF2S2,KIAA1671,SLC38A5,INTS7,MCM5,NOC3L,ANP32B,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,PEA15,GTF2H3,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EIF4A2,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,LEMD3,SURF1,ZNF160,GPN1,WDR33,MB21D2,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,PDK4,MYH9,AGAP6,NECAP1,TUBB6,SAFB2,EEA1,HSPA1A,STAM,RPP30,PRKD3,BCAS2,ABCA12,ERI1,ZKSCAN1,FMNL1,ATRIP,GSTA4,CEP63,LSM10,GARS,KRT7,FAM111B,ARHGEF10,LGALS1,ADAM32,TTC28,FKBP3,FGFR1,PDE8B,HLA-DMA,TAF2,GNG2,PES1,IQCH,CDC16,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,SERINC5,ZNF786,XPC,SESTD1,TRAK1,C1orf226,ID2,SF3A3,WDR37,AKT1S1,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,DIS3L2,DDHD1,C21orf58,FAM98A,FBXO17,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,MRPS10,FAM126B,IL6R,PDE3B,DDX49,FOXC1,CASC1,RPA1,KISS1R,ETFDH,TOE1,TRIB3,BAZ2B,PXDN,NME1-NME2,POLE2,STX1A,ARID3B,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,BCAS4,FAM227A,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,XRCC2,PPCDC,UBAP2L,ZNF85,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,ZNF124,SLC3A2,GCNT2,HARS,BAZ2A,ZNF414,SKIV2L2,MED27,GDPD1,COL4A3BP,GMFB,BRCA1,ZNF91,CCDC28B,PEX1,KIF16B,GLS,ZNF622,MSRA,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,TMEM158,CHMP4C,SEPHS2,NOMO3,SARS,AOC3,PGPEP1,MCM6,STX8,LRRC28,ITPRIP,HSD17B10,MEX3A,HES6,ZFP36L1,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,GTF2H1,SYNJ2,GMDS,ALDH18A1,NT5E,NAA38,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,TRAPPC6B,NR2F1,VAC14,PGD,NAP1L5,ATXN7,ITPRIPL1,FAM135A,SPAG9,PALB2,SYNCRIP,SNAP23,DNAH17,TBPL1,PPP1R12B,ZNF430,ARHGAP12,HMBS,NAPA,PRKAR2A,TESC,KCTD7,CYLD,GPR143,PPP2R2A,RNF24,LPCAT3,ZNF83,ZNF709,PELP1,KDM1A,CAD,METTL16,UBR1,ARMC5,DNAJB6,IKBKB,ZDHHC6,C15orf40,ZFP37,ETF1,RNF2,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,PCGF3,EVL,TUBA1A,NARS,GLTSCR2,THSD4,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,CLEC16A,ITGA2,TSSC1,ZNF436,PRRT3,ZNF18,NFASC,PUS1,SEPT5,ATXN7L2,UNC13D,MAP3K13,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ANXA7,IFIT5,HIST2H3D,PRICKLE2,DDX31,CD44,PCK2,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZMYM5,TPM4,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,SRBD1,GPC2,ZBTB8OS,SET,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRKAB2,TNFRSF21,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,CEP135,MEIS3,FUT11,SEH1L,TBC1D8,DDN,DPF3,SETD1B,ATG9A,ALDH1L2,EYA3,GNG7,CUX1,FOXRED1,MAK16,SH3GL1,SKIL,HSDL2,FAM122C,ZNF81,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,IFT57,DROSHA,CELSR1,EGR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,TGFBR2,CHD5,CD226,IGF2BP3,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ENTPD5,ASAP1,COPS3,ATIC,VWDE,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,AOC2,POLA1,KIAA0586,TTYH2,PTPN12,PLCB1,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,NSF,ZZEF1,ZBTB12,RIOK3,PURB,PEX13,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,RTTN,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,URB2,HFM1,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,TMEM184A,SHC1,KDM2A,GLYR1,VGF,NBEA,SSBP1,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,NAA35,ZCCHC14,RFC4,MPP6,RFC3,PDK1,MTIF2,WDPCP,DLG4,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,VDR,HTR7,YIPF2,DNAJA3,ZNF236,H2AFX,ACP1,ALKBH1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NOLC1,TROVE2,NCOR2,TMEM212,CA11,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,MLH1,NOL3,IKBKAP,GDPD5,FOXO3,TMCO6,NEDD4,MAD2L2,ZNF239,DCTPP1,RGS17,PTRF,NISCH,PMPCA,HARS2,UPF2,COPS7B,NLGN3,EXOSC4,LARP4B,PLEKHG4,FAM120B,TSHZ1,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,OASL,MMAA,ECH1,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,STX18,RNF138,MYOM2,BRWD3,RABEP1,SLC43A1,STK4,LRRC41,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,GPR87,ANAPC10,RELB,JOSD1,PCOLCE2,POLR3B,SLC27A5,NDUFA6,OGG1,TRIM14,PRKACB,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,TRIM13,TXLNG,ZNF680,CMIP,HDAC8,SOX4,TCTN1,SERGEF,CDHR3,TAF9B,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,PQBP1,ABCC3,GALNT10,ZNF397,COPS6,DMTF1,TNRC6A,SLC12A7,RELL2,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,PAX2,ALG8,MED13L,XPO7,PHGDH,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,CCDC112,SEMA3D,GLTP,NRIP1,N4BP2,CPSF3L,RANBP6,KRT20,PDE4A,TBXAS1,PSMA1,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,RRAGA,EXOC4,HK2,KIAA1328,ZFP90,C12orf45,C7orf26,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,CSTA,GBF1,ZSCAN5A,VPS18,FARSA,BRE,CAMTA2,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,MCEE,ACSL5,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,ATP8B2,RAB10,PUSL1,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,USP11,ECHDC1,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SULT1C2,SH2D3A,DBF4,NSUN6,CLSTN2,PPHLN1,PPP1R1C,MFSD10,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,SHMT2,CLDND1,TTC17,AMOT,DMRT1,PAQR6,IL11RA,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,TARS,RERE,HSPA1B,ZNF708,ALG5,MPP7,ZNF330,CUL2,ZRANB2,MBD6,TATDN1,MMP16,ZAK,HRH1,CTXN1 |
| 3.581e-04 | -7.93 | DNA replication | biological process | GO:0006260 | 214 | 46 | 16441 | 2138 |
DNAJC2,POLB,MCM6,MCM10,ATRX,C10orf2,DBF4,TNKS1BP1,RMI1,MCM9,RPAIN,TERF2IP,SLX4,MCM5,ATRIP,SSBP1,FHIT,POLE3,NT5M,TERF2,TOP1,RFC4,RFC3,APEX1,PRIM2,GINS3,POLK,POLA1,NOL8,NFIA,LIG4,BRCA1,MCM2,DKC1,POLG2,ZRANB3,RPA1,CHAF1A,BAZ1A,BRCA2,POLE2,DNAJA3,CDK9,SET,ORC5,DTD1 |
| 3.624e-04 | -7.92 | TGAGATT,MIR-216 | MSigDB lists | TGAGATT,MIR-216 | 107 | 27 | 17758 | 2279 |
GATAD2B,PPP1R9B,LAMC1,UBN1,WDFY3,GPBP1L1,CRIM1,PCCA,SMAD7,NHS,ADAMTS6,AKT1S1,ARID1A,MEF2D,MBNL2,POM121,RPGRIP1L,RAB10,PRKCE,MYBBP1A,IKZF4,TBX3,RNF138,ETF1,MMP16,SMG1,HNRNPM |
| 3.632e-04 | -7.92 | DDX1 (DEAD (Asp-Glu-Ala-Asp) box helicase 1) | protein interactions | 1653 | 123 | 32 | 16036 | 2270 |
CUL7,FN1,PLOD1,HSPA1A,IGF2BP3,NUP133,MYC,SHMT2,ALDH18A1,YBX3,SRRM2,HNRNPM,RPS6KB2,FAM98A,RFC4,TSTA3,FKBP3,ABCF1,SAP30BP,RPA1,DYNC1H1,POP1,GEMIN5,NME7,LSM14A,COPS5,CUL2,ATM,EIF2S1,FUS,EIF2B3,POLR1C |
| 3.643e-04 | -7.92 | negative regulation of transcription, DNA-templated | biological process | GO:0045892 | 1162 | 190 | 16441 | 2138 |
ATRX,PPARGC1B,BCOR,SIRT2,SKI,SREBF2,ZFHX3,YLPM1,JAZF1,RELB,ZEB1,ZNF148,FNIP2,KDM5C,HCFC2,PTPRK,DEAF1,HMBOX1,RBCK1,AEBP2,SIRT6,PPARG,BAZ2A,NR6A1,EHMT1,NFIA,MINA,CUX1,HDAC8,CAV1,BRCA1,ZNF91,SPOP,DOT1L,TAF9B,GZF1,PAF1,UBTF,SKIL,TCF7L1,SUPT4H1,SUFU,GATA6,CC2D1B,PER1,HIC2,DLX2,ZC3H8,BEND6,BMI1,MEF2C,FOXO1,EGR1,ZHX3,KHDRBS1,PAX2,SIRT7,SMAD7,HES6,BARX2,ZIC2,RSF1,CDC73,MLX,HR,MBD2,MYC,VPS72,SAMD11,CTR9,TIMELESS,NRIP1,MYB,GATAD2B,ZNF675,PAXBP1,RREB1,PRDM16,ARID5B,WWC1,PRDM1,ARID1A,NELFA,SUPT5H,PLCB1,TRIM37,TCF7L2,NR2F1,ZNF425,CAT,MYBBP1A,EHMT2,SPEN,IRAK2,CCDC85B,PURB,ZFP90,TBL1X,NCOR1,N4BP2L2,USP7,ZNF254,ZNF706,DLL4,ID1,CYLD,MAP2K5,RBFOX2,SMARCA4,PBX1,RING1,KDM1A,ZBTB21,PPID,DNAJB6,RNF2,SAP30,MOSPD1,KAT8,PRAME,KMT2D,POU2F1,ATXN1,SATB2,FGFR1,SNCA,BATF3,VDR,ZC3H12A,SMAD3,MSX2,RBBP8,IKZF4,ELP2,SIX5,HIPK2,DNAJA3,KLF4,ARNTL,H2AFX,TRAF3,SETD6,YEATS2,HMGA2,NOSTRIN,NCOR2,TCF3,H2AFJ,NFX1,ID2,ATF7IP,GAS6,BHLHE40,RPS6KA5,FOXP1,BMP6,FOXO3,HIST2H2AB,MAD2L2,NEDD4,SNW1,SUV39H2,TAF3,HIST2H3D,YBX3,DMRT1,SOX6,FGF9,MSX1,KDM5B,FOXN3,PSPC1,SCMH1,HIST1H4J,PDE2A,MEN1,UBC,DKK1,MKX,RERE,TRIB3,NSD1,TBX3,SET,RBPJ,BMP4,NR2F2,IGBP1,DDIT3,KAT6A |
| 3.647e-04 | -7.92 | PPARA activates gene expression | REACTOME pathways | R-HSA-1989781 | 112 | 29 | 8202 | 1117 |
FADS1,CHD9,PPARG,NPAS2,TEAD1,TNFRSF21,PPARGC1B,MED27,MED13L,SMARCD3,MED18,MED16,CPT1A,ANGPTL4,PLIN2,TRIB3,NRF1,SREBF2,ACOX1,MED15,ARNTL,MED24,ME1,TBL1X,MED20,NCOR1,CARM1,FDFT1,HMGCR |
| 3.652e-04 | -7.92 | GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_UP | 187 | 41 | 17758 | 2279 |
SEPHS2,C9orf78,CELSR1,MFGE8,SIRT7,PDE4B,PPHLN1,SF3A3,SIRT2,RSF1,RLF,LCLAT1,UBR5,NDUFS7,CHD7,ABL2,EXOC1,DHX33,NISCH,KDELC1,PPCDC,NDUFA6,CD44,TRIM14,DDX28,FMNL3,DNMBP,PPP1R21,PREX1,ZNF512B,YIPF3,PHF6,TMEM206,YTHDF2,ARID3B,CDK9,SURF1,TBL1X,POLR1C,PRKAR2A,PPIL3 |
| 3.661e-04 | -7.91 | rhabdomyosarcoma | COSMIC cancer mutations | rhabdomyosarcoma | 4310 | 618 | 17775 | 2278 |
ARHGAP26,GGT1,DCP1B,CACNA1H,SBF2,CSPP1,CCNL2,SYNJ1,SKI,C1orf159,PDZD2,ZFHX3,MAD1L1,PDS5B,HRG,AVEN,SRRM2,CCDC57,NRAS,KLHL23,PTPRM,NFIA,KIF15,RFX2,ABCC2,SLC50A1,AHNAK,BRCA2,RUNX1,HERC2,EP400,TMEM63C,SIRT7,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,SLC1A1,ABCA7,RSPRY1,SH2B3,RBM20,DDX56,KIAA1671,INTS7,ANP32B,GEMIN4,NOC3L,CCDC88C,COQ3,ZNF518B,AGL,FMNL2,NOM1,HMGCR,COL17A1,KCNQ3,MYO10,RB1CC1,PRDM16,ARID5B,EPS15L1,RYR2,SMARCD3,MAP7D1,CPT1A,TRIM37,EVI5,NCDN,IRS1,DYNC1H1,VPS13C,LRP1B,GTF2A1,GSTO2,PDLIM1,ZNF160,WDR33,PDLIM5,ZNF516,MYH9,AGAP6,ISG20L2,TUBB6,RPGRIP1L,SETD5,FMNL1,WAC,CLCN6,MSH4,PEG10,DENND1A,GARS,KMT2D,FAM111B,EIF3J,ARHGEF10,GSTCD,TTC28,DSP,VPS53,MAT2A,FGFR1,ZFAND3,PES1,ASTN2,HIPK2,METTL6,POLR3E,PAM,LAMA5,METTL2B,YEATS2,CATSPERG,BAG1,MAPT,TRIM36,MORC2,XPC,ATG2B,BHLHE40,PSMF1,TAF3,UNC13A,ACOT11,ARHGAP1,SOX6,HNRNPM,SPTAN1,DIS3L2,DDHD1,C21orf58,ERICH1,POLK,ZC3H18,LDHA,ZNF467,CCDC150,ETFDH,RARS,SRCAP,NSD1,PXDN,HERC1,PTPN4,AEN,GPAM,SORCS2,DOCK6,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,PPARGC1B,MFGE8,RNF43,FAM13A,SEC16A,SCAF8,MAP2K3,FRRS1,TRMU,XRCC2,ANKRD11,MPST,VPS13B,METTL1,FLNC,DSC3,FMNL3,CHD9,ABCC4,MIOS,BAZ2A,SKIV2L2,PPARG,ANK2,LAMA2,BRCA1,KCNH2,CRYBG3,PEX1,BSN,DYRK1B,GLS,TCF7L1,MSRA,TP53BP1,PER1,TNFRSF1A,ADAM9,CTU2,ITFG1,PRSS3,SMAD7,MEX3A,HES6,RLF,ARID1B,DNAH1,DOPEY1,CEP290,PDE10A,VAPB,SYNJ2,CWF19L2,LRSAM1,SNX29,NT5E,SETD2,HAUS6,BCS1L,OBSCN,CYB5B,ACOXL,NR2F1,TCF7L2,ATXN7,FAM135A,SPAG9,PALB2,SNAP23,DNAH17,CASS4,BCCIP,ID1,PAPD4,UPK3B,ARID2,ZNF83,LPCAT3,DENND3,RADIL,ZNF121,DDX60L,PELP1,PLXNB1,FDX1,KDM1A,ZNF608,JAG1,NUP133,GRIN2C,UBR1,ARMC5,DNAJB6,CCDC40,HIBCH,ANO8,MYH15,CASP10,CTC1,TMEM200A,KDM3B,SEC24A,SOBP,WDR36,PCGF3,SSFA2,GLTSCR2,THSD4,ANKRD33B,RAB7A,MANBAL,VIM,AKAP13,NHSL1,NUP214,BTBD11,ATP5D,EXO1,SLC30A3,LMBR1L,SIX5,ZNF333,CLEC16A,ITGA2,ATG7,TSSC1,INTS9,PRRT3,NFASC,MUTYH,PARD3,ATXN7L2,ZNF507,UNC13D,C14orf159,MAP1S,RBM19,FOXP1,RMI1,POGZ,BZW2,ZNF594,ANKRD54,IQGAP2,PTPN2,FAM50A,PRICKLE2,DDX31,POLR1B,CPNE7,FAM71E1,ADAMTSL3,LRRIQ1,C22orf34,ARHGEF12,C11orf49,RHOT2,ARMC3,SMPDL3B,NEU1,ZRANB3,TPD52L2,DSC2,TAF4,GLG1,BCAS3,USP20,RBPJ,NR2F2,C6orf223,ZNF292,CGN,MYCBP2,NBEAL1,RAC3,AARS,UBR5,LPIN1,GIPR,RNF111,CEP135,CSGALNACT2,ZNF646,TBC1D8,ACADS,SLC38A6,CUX1,TCEB3,EFHC1,ZDHHC14,SON,DENND4A,PLCXD2,OSBPL1A,TRRAP,VPS13D,DNAH2,TXN2,BLMH,ZNF598,SPOCK3,PTPN14,WDR75,IFT57,JUP,CELSR1,LARS2,ZHX3,DLGAP4,CCDC47,PRPF39,CD226,MTUS1,TECTA,FAM192A,NAV1,HR,TSPAN2,SCAF1,COPS3,VWDE,PIGG,GTF3C3,CNOT4,FDFT1,SIK3,RREB1,POLA1,KIAA0586,TTYH2,PTPN12,ARID1A,MTR,ANGPTL4,ARIH2,LYRM7,ATP9B,ZNF425,DAGLA,ASCC3,PMEPA1,ZZEF1,SRP68,D2HGDH,DPEP1,CNDP2,ZFHX2,CPT1C,TBKBP1,AMOTL1,TRPM2,SYT17,NDUFB5,PTPRG,PABPC1L,AP1B1,LTB4R,TRIM66,CHD7,ZNF827,DECR1,TMEM184A,KDM2A,VGF,DTNBP1,NBEA,TTC3,PNPLA4,RFC4,ZCCHC14,GON4L,WDPCP,DLG4,KIAA1586,GNL1,SATB2,MEGF11,MED16,DCBLD2,G6PD,DNAJA3,ACP1,IFT140,MDN1,PDCD11,XRCC4,NCOR2,BRAF,C10orf2,NFX1,RCAN1,RTN4,MLH1,DNAJC22,INPP1,GIGYF2,NEDD4,ABL1,PMPCA,UPF2,FER1L5,WDFY3,PACS1,MMAA,YIF1A,ZFP62,DDX50,HELZ,STX18,ATM,MYOM2,APAF1,LRRC41,LETM1,PHF3,MVK,NF1,ATRX,SLC52A3,KIF5A,FANCD2,TRPM6,PLOD1,BCOR,STK33,SNAPC4,SMARCB1,SLC30A7,ZNF804A,RTN1,LONRF2,THADA,YLPM1,MYH3,GPATCH1,KIAA0922,B3GNTL1,NDUFA6,OGG1,CARM1,FBXW4,SIRT6,CMIP,ITPA,ARRDC3,TMEM216,SOX4,KMT2C,TCTN1,SERGEF,CHAF1A,GEMIN5,TMEM132B,CCDC3,CSMD3,CLU,EME1,ZC3H8,MTCH1,TNRC6A,SLC12A7,DCTN3,FN1,ZCCHC8,SCART1,PAX2,PCSK7,SMG7,EVPL,QSER1,SIPA1L3,MCAM,WDR27,SEMA3D,ZCCHC7,PRF1,NRIP1,ATP6V0D1,LRP3,N4BP2,MTHFD1,ZNF629,HBG2,KRT20,PDE4A,ELP3,JMJD1C,ZBED4,WWC1,EIF2A,PRDM1,ANKRD20A4,AGAP1,ISG15,DNAH14,SYCP2L,MYBBP1A,EP400NL,FAT1,HK2,ZFP90,TMEM182,TBCK,DMXL2,FEZ2,PCNT,CELSR3,TMEM183A,TNXB,MYO7A,SMARCA4,COBLL1,VPS18,ZNF142,MET,ZNF460,HTRA2,MAML3,NARS2,TFCP2,PARP2,GRHL3,METTL15,R3HDM1,ATXN1,EDEM2,ATP8B2,UBR4,ARMC4,ALAD,DUS3L,IKZF4,HYAL3,SRFBP1,SCARB1,DISP1,SMG1,NSUN6,ATF7IP,MFSD10,SFI1,PRKCH,SCN1B,KDELC1,SHMT2,ERI3,RPS6KB2,KDM6B,ARNTL2,CRIM1,ASAP3,METTL23,SCFD2,TMEM187,SYMPK,RERE,DAGLB,WDR35,ZRANB2,MBD6,TATDN1,ZAK,MMP16 |
| 3.681e-04 | -7.91 | peptidyl-amino acid modification | biological process | GO:0018193 | 929 | 156 | 16441 | 2138 |
DPH1,TRIM16,PRKCSH,KMT2E,PLOD1,PPIL1,SIRT2,PRKCA,NUP160,SEC16A,MAP2K3,ABL2,NEK6,KANSL1,CNIH3,DPH6,POLE3,SEH1L,CARM1,TNK2,SETD1B,BAZ2A,EHMT1,SUMO3,BRCA1,SGK2,ZDHHC14,KMT2C,ST3GAL5,DOT1L,DYRK1B,BRCA2,TRRAP,NSMCE1,PER1,CTAGE5,BMI1,SPOCK2,SPOCK3,HERC2,WDR75,EP400,TTN,CLK1,SEC24D,TAF1,ST6GAL1,ALG8,DPM3,TGFBR2,CHD5,FKBP1A,PRKCE,P3H1,USPL1,PPIL2,MED24,CTR9,PRMT5,MAP3K12,TRAPPC9,CAMKK2,ALG6,WDR61,STAG1,ELP3,SETD2,ATAT1,ST6GALNAC3,TRAPPC6B,MGAT2,SEC31A,EHMT2,NSF,SENP3,HMBS,NAPA,BRSK2,SMYD3,MAP2K4,MPI,ASH1L,MAP2K5,DDR2,RIPK1,NUP43,ST3GAL6,PIBF1,RING1,PHC2,CAD,SHC1,PPID,NUP133,ZDHHC6,IKBKB,RNF2,MET,KMT2A,PRMT3,KAT8,SEC24A,KMT2D,BRD4,SETD7,EDEM2,NUP214,FKBP3,FGFR1,CAMK2D,RANBP2,HIPK2,NSMCE2,CAMKMT,FKBP5,XRCC4,SETD6,PPIL3,YEATS2,SMG1,HMGA2,XPC,B4GALT5,TCF3,JMJD6,GAS6,CSNK1A1,RPS6KA5,POM121,MAN1A1,TADA3,ABL1,ADH5,SUV39H2,CWC27,SEC24C,CLK2,PXN,TTLL5,SCMH1,PTK2,MEN1,PEAK1,NEU1,RPA1,OXSR1,SRCAP,NSD1,ALG5,ZDHHC11,AGTPBP1,SRD5A3,ATM,TAF12,STK4,KAT6A |
| 3.683e-04 | -7.91 | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP | MSigDB lists | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP | 65 | 19 | 17758 | 2279 |
PTP4A1,GON4L,TTC27,BCS1L,PCMT1,SMARCA4,ISG20L2,PHGDH,EIF5B,PTPN2,NPRL2,FBXO21,STX18,ZDHHC6,RNF138,HIC2,TBPL1,DDX10,TMPO |
| 3.683e-04 | -7.91 | PID_HDAC_CLASSI_PATHWAY | MSigDB lists | PID_HDAC_CLASSI_PATHWAY | 65 | 19 | 17758 | 2279 |
GATAD2B,NCOR2,TFCP2,SIRT6,PPARG,SIRT7,SMAD7,HDAC8,RANGAP1,SIRT2,FKBP3,RANBP2,CHD3,MBD2,TNFRSF1A,NCOR1,RAN,PRMT5,SAP30 |
| 3.684e-04 | -7.91 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_DN | 193 | 42 | 17758 | 2279 |
WDR75,SARS,INSIG2,SPRYD7,PRAF2,RIPK1,LPCAT3,ST7L,GYG1,CMTM3,MAP2K3,CAD,RSPRY1,SREBF2,ARMC6,MED24,BCAP29,SYNJ2,MET,HSD17B12,VOPP1,TNK2,GNL3,ZC3H18,HSPA5,RDH10,TFPI,PACRGL,PSMG1,NEU1,MAT2A,CLNS1A,PYCR1,BATF3,NAP1L5,TMCO1,ETFDH,SYNGR2,TRMT2A,SVIL,RNF130,USP11 |
| 3.684e-04 | -7.91 | GSE17721_LPS_VS_POLYIC_6H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDM_DN | 193 | 42 | 17758 | 2279 |
ADAM19,UBXN1,MYO7A,IQGAP2,FAM50A,ANKRD13A,HR,FMNL1,MYC,NDRG4,ANKRD24,SSBP1,CORO1A,PCK2,ALDH18A1,PLEKHA2,TMEM14C,CDC37,EVL,RREB1,PRIM2,MTIF2,POLA1,RAB7A,PSMG1,SCMH1,COTL1,CPT1A,SH3GL1,GNAI1,BAZ2B,RPL28,COQ9,EXOC4,RIOK3,SLCO5A1,KLHDC4,RNF130,ECHDC1,MUTYH,NIT1,MEF2C |
| 3.713e-04 | -7.90 | - | gene3d domains | 1.10.150.60 | 15 | 8 | 9988 | 1398 |
KDM5B,ARID3B,ARID2,KDM5A,ARID5B,KDM5C,ARID1A,ARID1B |
| 3.718e-04 | -7.90 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | 205 | 44 | 17758 | 2279 |
SRM,NCOR2,TBKBP1,THOC5,LETM1,MCM10,PPARGC1B,SLC2A1,TMEM104,ISG20L2,SLC29A1,SPATS2L,AP1B1,BHLHE40,SNAPC4,PIP4K2A,PHLDA2,FLNB,HR,LONRF2,STC2,MED24,GREB1,RAPGEFL1,POLR1B,MYB,IFRD1,CHD9,GINS3,NOL6,WWC1,FOXC1,MAT2A,CCDC3,POP1,MYBBP1A,KDM4B,HK2,SNX24,SVIL,SLC25A19,NOLC1,GPATCH4,PKIB |
| 3.721e-04 | -7.90 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 211 | 45 | 17758 | 2279 |
CCDC58,PDE4B,LAGE3,MAB21L3,DPM3,ZIC2,CHAC1,BHLHE40,FOXO3,POM121,DDIT4,NAMPT,DUS4L,PMAIP1,STC2,IGF2BP1,PRMT5,SRRM2,PLEKHA2,PERP,SAP30,WDR36,TIMM8B,SESN2,PDK1,NR6A1,UPP1,NPM3,ARRDC3,CAV1,PDE2A,UBE2K,HPRT1,DCXR,NSMCE1,FAM114A2,FAT1,EXOC4,HK2,AEN,APAF1,ZAK,ZMAT3,PTPN14,CPT1C |
| 3.744e-04 | -7.89 | NMD3 (NMD3 ribosome export adaptor) | protein interactions | 51068 | 55 | 18 | 16036 | 2270 |
GARS,TTC27,WBSCR22,CSNK2A1,IMPDH2,DKC1,NOP58,AARS,FLNB,CIAPIN1,MAT2A,ZNF622,EPRS,ASNS,ARHGAP1,PUS1,POLR1C,PRPS1 |
| 3.767e-04 | -7.88 | HIST2H2BE (histone cluster 2, H2be) | protein interactions | 8349 | 113 | 30 | 16036 | 2270 |
GATAD2B,PRAME,CUL7,USP49,ATRX,SIRT7,USP42,SMARCA4,RPS6KA5,ARID1B,PELP1,USP46,UBC,POLR2A,RNF40,KPNA1,PALB2,ZSWIM7,GADD45A,CDK9,HIPK2,COPS5,CUL2,H2AFX,HIRIP3,FUS,TBL1X,STK4,SAP30,USP15 |
| 3.798e-04 | -7.88 | ZHANG_TLX_TARGETS_60HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_60HR_DN | 266 | 54 | 17758 | 2279 |
SRM,DNAJC2,MCM6,MCM10,DBF4,SMARCA4,VARS,NUP43,NUP160,DCTPP1,GART,INTS7,ERI1,UCHL5,MCM5,STC2,TIMELESS,SHMT2,RDX,PRPS1,TRIP13,CASP8AP2,TMPO,EXOSC2,RFC4,RFC3,PRIM2,PPAT,MYO10,SKIV2L2,POLA1,HAUS6,DLG4,WDHD1,BRCA1,MCM2,SON,EXO1,EPRS,RBBP8,SYNCRIP,POLE2,RAD18,HNRNPR,ZBTB12,HK2,EIF2S1,ATM,FKBP5,UMPS,EME1,WDR33,NOLC1,TNRC6A |
| 3.865e-04 | -7.86 | One carbon pool by folate | KEGG pathways | ko00670 | 20 | 9 | 6908 | 881 |
GART,MTHFD2,ATIC,ALDH1L2,SHMT2,MTHFD1L,MTHFD2L,MTR,MTHFD1 |
| 3.865e-04 | -7.86 | One carbon pool by folate | KEGG pathways | hsa00670 | 20 | 9 | 6908 | 881 |
GART,MTHFD2,ATIC,ALDH1L2,SHMT2,MTHFD1L,MTHFD2L,MTR,MTHFD1 |
| 3.901e-04 | -7.85 | microtubule organizing center | cellular component | GO:0005815 | 608 | 106 | 17570 | 2233 |
RTTN,CUL7,ID1,RAB11FIP4,CYLD,BIRC6,PCNT,PAFAH1B1,OLA1,MKS1,TUBE1,TBCCD1,CSPP1,SIRT2,PIBF1,HSPA1A,RPGRIP1L,SKI,BLOC1S2,NEK6,XRCC2,MAD1L1,RELB,SUCLG2,FNIP2,RAN,CEP63,CEP135,PXK,CDK6,PRKACB,CEP128,ATF4,EYA3,KIF15,ARHGEF10,CAMSAP2,EFHC1,BRCA1,TTC28,UBR4,CCDC28B,GNAI1,DDAH2,IFT81,CDC16,BRCA2,RAD18,IKZF4,CHD3,G6PD,CCDC146,PQBP1,IFT140,TSEN2,XRCC4,C2CD5,CEP170,DCTN3,HERC2,KIZ,IFT57,PAX2,DPF2,PDE4B,SMAD7,ID2,CEP126,CSNK1A1,MBNL1,SFI1,MTUS1,CEP164,CEP290,DCTN4,CCDC124,FBXO31,ATP6V0D1,AKAP11,CEP83,VPS37A,TTLL5,APEX1,IFT43,CEP295,RAP1GAP2,HAUS6,KIAA0586,PSMA1,CCDC113,PTK2,EVI5,HSPA1B,IRS1,YIF1A,DYNC1H1,KLHL22,SPAG9,NME7,WDR35,SDCCAG8,CCDC85B,USP20,SLC16A1,BRSK2,PRKAR2A |
| 3.956e-04 | -7.84 | NGUYEN_NOTCH1_TARGETS_DN | MSigDB lists | NGUYEN_NOTCH1_TARGETS_DN | 86 | 23 | 17758 | 2279 |
GARS,APEX1,TRIO,PNN,UBR4,SERP1,TARS,HERPUD1,RING1,PCDH7,DYNC1H1,MGAT2,DDAH2,MTHFD2,KLF4,MYC,ITGA2,STC2,SERPINH1,LAMA5,HTRA2,SGSM3,SRPK2 |
| 3.966e-04 | -7.83 | SENESE_HDAC3_TARGETS_DN | MSigDB lists | SENESE_HDAC3_TARGETS_DN | 490 | 89 | 17758 | 2279 |
CYP24A1,LIN28B,BTBD2,PLRG1,CD99L2,NECAP1,PRKCA,CSTA,AARS,EEA1,PCDH7,ASNS,VGF,NCKIPSD,TSPAN14,TMEM120B,YARS,SLC25A23,SEH1L,CARM1,GDAP1,GCNT2,AEBP2,COL5A2,ATG9A,NPM3,NFIA,TAF9B,GNAI1,SNCA,VDR,SLC39A14,EPN2,AHNAK,TRMT5,MKL2,H2AFX,GALNT10,NFASC,MED20,TPM1,XRCC4,SYNPO,PARD3,CHMP4C,TMCC1,TNNC1,NCOR2,SARS,MCM6,MIF4GD,EGR1,STXBP6,FAM46B,TCF3,TGFB2,PHGDH,GDPD5,PHLDA2,FAM49A,MFSD10,MCAM,PTRF,NISCH,DCTN4,CTR9,PLEKHA2,N4BP2,HSD17B12,ZNF629,LRRC20,FADS1,PSAT1,KIAA1143,CRIM1,ZNF512B,TPM4,CYB5B,UBE2K,ARIH2,VAC14,NEU1,CTIF,IREB2,PDLIM1,GTF2A1,MPP7,TBPL1,ZAK |
| 4.007e-04 | -7.82 | BCL7C (B-cell CLL/lymphoma 7C) | protein interactions | 9274 | 22 | 10 | 16036 | 2270 |
DPF3,SMARCC1,ARID2,BANF1,DPF2,SMARCA4,SMARCD3,ARID1A,ARID1B,SMARCB1 |
| 4.011e-04 | -7.82 | IVANOVA_HEMATOPOIESIS_STEM_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL | 242 | 50 | 17758 | 2279 |
PPDPF,MYCBP2,ASH1L,EGR1,LUZP1,KIF5A,ZBTB37,MEX3A,PDE4B,SMAD7,COBLL1,PPP1R9A,DDIT4,IQGAP2,PRKCE,CHN1,ENTPD5,SYN2,SEMA3D,HYAL1,ETV1,PRKACB,PTPRK,SCAF11,MSI2,MARCH9,VPS37A,ANAPC13,TSPYL4,MYO10,TEAD1,ABCF2,PLAC8L1,SCFD2,SULT4A1,GNL1,ARHGAP32,PEAK1,RBM28,TTC28,POLR2A,SLC23A2,PGD,SKIL,IFT81,MBTD1,CDKAL1,TBXA2R,RBP1,CHMP4C |
| 4.029e-04 | -7.82 | PAXIP1 (PAX interacting (with transcription-activation domain) protein 1) | protein interactions | 22976 | 254 | 56 | 16036 | 2270 |
MCM6,PRDX6,DDX18,PAX2,PPHLN1,CSNK2A1,HNRNPLL,POM121,KRI1,ANAPC1,SRSF2,BRE,EIF2S2,INTS7,DYNC2H1,CPSF3,YBX3,PRMT5,SRRM2,POLR1E,CDK12,NOM1,TMPO,RFC4,KMT2D,PPARG,LIMA1,TRA2A,WDR18,LDHA,WDHD1,CCNDBP1,DKC1,KMT2C,EIF5B,ZNF251,EIF3H,RPA1,STOML2,ZNF622,CDC16,TP53BP1,PER1,CDK9,RLTPR,H2AFX,C7orf50,UMPS,CLU,PGAM5,BRCC3,FAHD1,PDCD11,CATSPERG,ANAPC4,GPATCH4 |
| 4.039e-04 | -7.81 | KCNMA1 (potassium channel, calcium activated large conductance subfamily M alpha, member 1) | protein interactions | 3778 | 15 | 8 | 16036 | 2270 |
GGT1,KCNMA1,CACNA1H,PTK2,CAV1,HMOX2,TBXA2R,CAV2 |
| 4.076e-04 | -7.81 | ATPase activity, coupled | molecular function | GO:0042623 | 310 | 62 | 16491 | 2164 |
MCM6,ABCA3,ATP6V1A,DDX18,ATRX,DDX19A,MYO7A,MYH9,SMARCA4,CHD5,HSPA1A,DHX35,ABCA7,DDX56,ABCA12,DHX37,LONRF2,ABCA5,DHX33,XRCC2,MYH3,GTF2H1,DDX31,CHD2,MSH4,ATP6AP1L,ATP6V0D1,LONP1,TOP1,SKIV2L,RFC4,DDX28,GTF2H3,RFC3,DDX41,ABCC4,DDX24,MYO10,KATNAL1,EIF4A2,DHX34,ATP6V0A1,ABCC2,ATP8B2,DDX49,DHX57,HSPA1B,RAD54B,ATP5D,PEX1,ANXA1,ATP9B,DDX3X,ASCC3,DDX50,RAD18,NSF,CHD3,MSH3,RAD51B,ABCC3,DDX10 |
| 4.102e-04 | -7.80 | GSE9037_WT_VS_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_BMDM_UP | 188 | 41 | 17758 | 2279 |
FEM1C,ZNF280C,PBX1,IKBIP,PRKCA,CDC73,IGF2BP3,TOX4,NUBPL,RRN3,PRKD3,ANXA7,DNAJB6,BANF1,TANK,NBEA,FNIP2,CMPK1,NRIP1,CDK12,LYST,DDHD1,EIF4E3,TFCP2,GPCPD1,JMJD1C,MANBAL,UTP15,MSRB3,VIM,PTK2,KLF6,EHBP1,MAT2A,GZF1,PWP1,DUS3L,LSM14A,CHD3,TBPL1,NR2F2 |
| 4.102e-04 | -7.80 | AAAGACA,MIR-511 | MSigDB lists | AAAGACA,MIR-511 | 188 | 41 | 17758 | 2279 |
KLHL24,ZNF706,THOC5,MINK1,FN1,ATRX,KLHL18,HLTF,IGF2BP3,RPS6KL1,MBD2,DCTN4,CELF1,IGF2BP1,WNT16,MRPL21,CNOT4,CLK2,ADAMTSL3,CRIM1,ZNF654,FOXN3,KCNMA1,PSMA1,SEMA3F,MAPK1IP1L,SATB2,CORIN,ONECUT2,YTHDF2,DDX3X,DYRK1B,PMEPA1,LUC7L3,RPS6KB1,RBM26,MBD6,FIP1L1,SLC25A26,TNRC6A,LPP |
| 4.130e-04 | -7.79 | GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP | 194 | 42 | 17758 | 2279 |
LETM1,PPARGC1B,OLA1,JMJD6,FAM8A1,ARID1B,RPAIN,FLNB,NDUFS7,PTPN2,UBE3A,UBR1,DHX33,PYCRL,KDELC1,PARP2,ZC4H2,CDK4,TFPI,METTL15,SLC35D1,ODC1,NUP214,PHF6,POP1,ZNF622,EPRS,ZNF266,POLE2,DUS3L,NME7,PDLIM1,DCXR,LUC7L3,MKL2,TSSC1,NCBP2,GPAM,DHCR7,GCSH,IPO4,RNF114 |
| 4.131e-04 | -7.79 | nucleobase-containing small molecule metabolic process | biological process | GO:0055086 | 504 | 92 | 16441 | 2138 |
NDUFA5,SUCLG1,ATP6V1A,NDUFB5,OLA1,NT5C3A,COX10,PUDP,HSPA1A,AHCYL2,PDE3A,NDUFB3,FLAD1,CAD,AMPD3,ATP5G2,PPCDC,MYH3,NT5C,ME1,FHIT,CMPK1,NDUFA6,AHCYL1,FXN,MTHFD2L,OGG1,MCEE,GARS,ITPA,UPP1,DLG4,ATP6V0A1,NUDT15,DLST,MAT2A,PDE8B,ATP5D,STOML2,SNCA,HPRT1,DCXR,PEMT,G6PD,MUTYH,AK2,SULT1C2,MRI1,AK6,PDE4B,CHCHD10,APRT,RNASEH2B,NDUFS7,NAMPT,DCTPP1,GART,NDUFV1,ENTPD5,PDE10A,ATIC,NT5M,PRPS1,NT5E,HMGCR,MTHFD1,PFKFB4,BDNF,PDE4A,PPAT,SMARCAD1,IDH3G,LDHA,SULT4A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,PGD,CAT,NME7,COQ9,HK2,TBPL1,SURF1,UMPS,NDUFS5,BPNT1,MACROD1,ADK,PDE9A |
| 4.153e-04 | -7.79 | MORF_EIF4E | MSigDB lists | MORF_EIF4E | 81 | 22 | 17758 | 2279 |
KDM3B,GTF2H3,PMS1,ANKRD17,DDX18,LARS2,SFSWAP,POLA1,MARS,VARS,BMS1,TTI1,EIF5B,ABCF1,MFN2,TAF2,RANBP2,RAP1A,CEBPZ,CTR9,NFRKB,XPO6 |
| 4.156e-04 | -7.79 | - | gene3d domains | 3.40.50.150 | 115 | 30 | 9988 | 1398 |
METTL1,SRM,RNMT,METTL23,NSUN6,METTL2A,WBSCR22,PCMT1,METTL15,METTL22,GSTCD,CIAPIN1,DOT1L,METTL16,TRMT5,METTL6,ALKBH8,CAMKMT,FTSJ1,METTL8,TRMT2A,NDUFAF5,FBL,PRMT5,TRMT12,COQ3,PRMT3,FTSJ3,METTL2B,CARM1 |
| 4.158e-04 | -7.79 | GGGAGGRR_V$MAZ_Q6 | MSigDB lists | GGGAGGRR_V$MAZ_Q6 | 2165 | 328 | 17758 | 2279 |
ADAM19,TMEM109,SBF2,SYNJ1,UBR5,PCDH7,SYN2,ATP5G2,PDS5B,RNF111,CHD2,CEP135,SRRM2,ZNRD1,CDK6,ZNF646,HMBOX1,NRAS,RNMT,NR6A1,ENHO,AKAP12,ZDHHC14,SON,DDX3X,DDAH2,TRRAP,AHNAK,LUC7L3,HIC2,NRP1,ZNF532,LPP,CLDN15,EGR1,JUP,CDC42EP2,FAM189B,ANKRD17,OPHN1,RSF1,PITPNM1,SLC39A11,MTUS1,IGF2BP3,SH2B3,PRKCE,HR,CNST,TSPAN2,PI4KB,NOVA2,CACNB2,COPS3,MYC,TNPO3,MFAP2,IGF2BP1,CALN1,CNOT4,PABPC1,TERF2,MYB,LRRC20,BDNF,STAG1,RB1CC1,PRDM16,RDH10,RYR2,SMARCD3,ARID1A,SNAP25,ARRDC4,EHBP1,ONECUT2,NCDN,PHF6,DAGLA,IRS1,VPS13C,TSR1,GTF2A1,EHMT2,UBAP1,FGFBP1,CDK9,VCAN,SENP3,NCOR1,GALE,SPRED2,AMOTL1,TRERF1,PAFAH1B1,NPAS2,ZBTB37,ACTR3,DDR2,PTPRG,IGSF1,PHC2,SHC1,KDM2A,UCHL5,FMNL1,VGF,WAC,MMP14,NAA35,CDK12,CASP8AP2,MALL,GARS,LGALS1,PNN,GALK2,MARCH6,KCNH3,ERC1,SERP1,FGFR1,SNCA,ZFAND3,BAZ1A,HLA-DMA,SMARCC1,TROVE2,LAMA5,YEATS2,MAPT,HMGA2,SLC25A12,BHLHE40,DNAJC22,TGFB2,RPS6KA5,FOXO3,ATXN7L1,ABL1,PTRF,ACOT11,UPF2,RAPGEFL1,NLGN3,CELF1,S100A14,ERRFI1,ZNF710,FBXL19,LYPLA2,FGF9,ZFYVE1,LSM12,AGPAT4,KCNMA1,R3HDM2,UBE2K,POLR2A,DDX50,RNF138,BMP4,BRWD3,DOCK6,DDIT3,IPO4,CUL7,NF1,WDR13,BCOR,TTI1,SCAF8,AHCYL2,DST,SRSF2,JAZF1,SLC39A7,ANKRD11,ZEB1,ZMYM2,SLC25A23,ETV1,HCFC2,YARS,OGG1,FLNC,ZBTB17,AEBP2,SESN2,BAZ2A,SIRT6,SLC38A1,PPARG,GDPD1,ATG12,ZSCAN2,SOX4,KCNH2,KRTCAP2,MLLT10,C1orf122,UBTF,TCF7L1,EPN2,SUFU,PER1,TNFRSF1A,COPS6,TNRC6A,SLC12A7,RELL2,FOXO1,SEC24D,TAF1,STXBP6,PAX2,DPF2,SMG7,ZFP36L1,ZIC2,PHGDH,SAMD11,GTF2H1,LRSAM1,ZCCHC7,MSI2,TLE3,ELOVL6,HOMER2,WWC1,EIF2A,TCF7L2,HERPUD1,NR2F1,ATAD5,BICD1,SPAG9,SYNCRIP,SDCCAG8,FDPS,PPP1R12B,BRSK2,FNBP1L,N4BP2L2,TCF12,ID1,DLL4,PCNT,RBFOX2,SLC2A1,TNXB,SMARCA4,SSBP2,TNKS1BP1,PELP1,DENR,METTL16,NRF1,JAG1,SOCS1,CAMTA2,RPS6KL1,CYB5D1,ETF1,RNF2,CORO1A,VCL,C6orf89,TMLHE,MOSPD1,RTN4RL2,COL5A2,KIRREL2,RAB7A,SFSWAP,R3HDM1,POU2F1,TOR1AIP2,VIM,UBR4,S100A16,RAB10,TJAP1,ALAD,IKZF4,SIX5,HNRNPR,ZNF436,INTS9,ARC,SEPT5,ATXN7L2,HM13,MAP3K13,RFX1,HIST2H2AB,PRKCH,GART,SEC24C,DCTN4,STC2,CD44,AMOT,SLC6A16,PPP1R9B,MSX1,GPHN,IL11RA,ZNF821,PPP1R21,ZMYM5,PSMC3IP,RAP1GDS1,FERMT2,ARHGEF12,MEN1,PDE2A,DKK1,RERE,SET,TBX3,CUL2,CSRNP1,ZNF32,MBD6,RBPJ,NR2F2,KIF1B |
| 4.161e-04 | -7.78 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | 458 | 84 | 17758 | 2279 |
SSBP2,FAM13A,GBF1,DST,THAP4,VGF,XRCC2,LPIN2,ZNF142,WIZ,PNPLA4,TMEM120B,TBC1D8,SRPK2,SKAP2,ARHGEF10,LGALS1,SUMO3,MCL1,ZNF91,FGFR1,TAF9B,CCDC28B,PEX1,SMAD3,BRCA2,LMBR1L,INSIG1,KDM4B,H2AFX,SGSM2,TBXA2R,XRCC4,TSPAN5,ZNF589,MID1,DCTN3,NCOR2,PIGN,RHOBTB1,SUPT6H,ZHX3,TCF3,SMG7,ID2,LYRM2,C1orf50,RSRC1,SFI1,TMCO6,TADA3,RNF40,ABCA5,DCTN4,GLTP,RDX,CD44,NT5M,HNRNPM,MYB,USE1,PEA15,WARS2,CAMKK2,AP4S1,TPM4,WWC1,SCMH1,EIF5B,CPT1A,ISG15,ARIH2,MFN2,INF2,TSR1,RARS,TRIB3,BICD1,RPL28,ZNF32,NCOR1,TAF12,PSAP,DDIT3 |
| 4.178e-04 | -7.78 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | 97 | 25 | 17758 | 2279 |
CHD9,DROSHA,HARS,CRIM1,PCMT1,DPM3,CAV1,SPATS2L,COTL1,TGFB2,PARN,DENR,DKK1,DST,SRSF2,PTRF,SYNCRIP,IFIT5,WDR73,TTC3,NR2F2,TSPAN14,PRKACB,BAG1,PTPRK |
| 4.178e-04 | -7.78 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 | 97 | 25 | 17758 | 2279 |
METTL1,SRM,TNFRSF21,GNL3,HOMER2,HSPA5,MARS,BMS1,NOP58,MAK16,AARS,ANGPTL4,TARS,NOP56,ADH5,CAD,EPRS,SRSF2,HIF1A,RRAGA,XPNPEP1,RDX,PUS1,SYNPO,FTSJ3 |
| 4.200e-04 | -7.78 | HORTON_SREBF_TARGETS | MSigDB lists | HORTON_SREBF_TARGETS | 24 | 10 | 17758 | 2279 |
LSS,IDI1,INSIG1,ELOVL6,FDPS,SQLE,ME1,DHCR7,RDH11,FDFT1 |
| 4.211e-04 | -7.77 | response to stress | biological process | GO:0006950 | 3601 | 529 | 16441 | 2138 |
ASCC1,ACTG1,CHAC1,HLTF,HMOX2,NUP160,ABHD6,PABPC4,AMBRA1,MMP7,NEK6,SREBF2,PMAIP1,ZNF148,FNIP2,HRG,FXN,NRAS,UPP1,KIF15,MSRB3,C5AR1,MCL1,SHISA5,ABCC2,TMSB4X,STOML2,PYCR1,DDX3X,RBSN,BRCA2,RAD18,MPV17,RUNX1,TPM1,P2RY11,MEF2C,ADGRE2,HERC2,SLK,PIK3R4,SH2B3,INTS7,APLF,ALKBH8,CCDC88C,MAP3K12,ANGPT2,MYB,KLRD1,PEA15,FADS1,GTF2H3,BDNF,IFRD1,MYO10,RB1CC1,RYR2,USP10,ABCF1,USP46,IRS1,PDLIM1,TRAP1,FGFBP1,CDK9,ADGRE5,WDR33,MAP2K5,ZNF516,GTF2H2C,NPAS2,ACTR3,PDK4,MYH9,NUP43,MCM9,HSPA1A,ESAM,ZSWIM7,ACD,WAC,MMP14,ATRIP,MSH4,CEP63,PXK,MGLL,LYST,PMS1,LGALS1,DSP,FGFR1,PDE8B,GNG2,KDM4B,NSMCE2,HIPK2,POLR3E,RPS6KB1,BRCC3,BAG1,MAPT,HMGA2,SERINC5,INSIG2,XPC,ID2,ATG2B,GAS6,AKT1S1,IP6K2,TRIM22,TGFB2,PSMF1,POM121,SNW1,NPRL2,POLR3D,SUV39H2,ACOT11,ANXA5,PTGS1,PNMA1,SPTAN1,ULBP1,FGF9,POLK,LDHA,MRPS10,IL6R,UBE2K,PDE3B,UBC,ANXA1,RPA1,OXSR1,TRIB3,ETFDH,PXDN,POLE2,SLC25A19,AEN,GPAM,PSAP,BMP4,DOCK6,CUL7,PPARGC1B,NREP,BIRC2,GIT2,MAP2K3,ABL2,ECM1,COPS4,NCKIPSD,XRCC2,PTPRK,CDC37,ATF4,SLC3A2,ABCC4,MIOS,PPARG,CDK4,ATOX1,HSPA5,COL4A3BP,ATG12,SUMO3,BRCA1,MGST1,CXADR,MSRA,ZNF622,INSIG1,TP53BP1,TNFRSF1A,RAD51B,AHNAK2,DPP4,ADAM9,TTN,AOC3,FOXO1,PRSS3,MAPK8IP3,LAMTOR3,SMAD7,FAN1,TRIM15,PDE10A,PPIL2,NDRG4,GTF2H1,TIMELESS,VAPB,WNT16,CRADD,SETD2,OBSCN,TCF7L2,SPAG9,SYNCRIP,PALB2,SNAP23,IRAK2,HMBS,BRSK2,PRKAR2A,BCCIP,USP7,CYLD,SLC2A1,RIPK1,RPAIN,KDM1A,GRIN2C,NUP133,DNAJB6,IKBKB,CORO1A,SPIDR,CASP10,CTC1,PRPF19,DDX41,NUP214,EXO1,SMAD3,RANBP2,RBBP8,KLF4,ITGA2,ATG7,EIF2B3,MUTYH,PARD3,UNC13D,MINK1,MCM10,HM13,MAP3K13,AGO2,RMI1,PTPN2,ADH5,ANXA7,TMEM161A,IFIT5,HIST2H3D,FBXO31,CD44,SMARCAD1,FOXN3,TOP3A,RANGAP1,HIST1H4J,PIK3CB,CHCHD6,POLR3A,ZRANB3,POLR3G,TBX3,MSH3,BCAS3,GLG1,EIF2S1,FNTB,RBPJ,ITGB4,POLB,CUL4A,PRDX6,PRKCSH,TNFRSF21,TMEM109,PRKCA,AARS,UBR5,GIPR,RNF111,CHD2,SEH1L,ACADS,DPF3,ATG9A,EYA3,GNG7,DDX60,GNAI1,TRRAP,LSM14A,ARL6IP5,NSMCE1,CFD,TNFRSF10D,TXN2,ZMAT3,CELSR1,EGR1,DROSHA,ANKRD17,CCDC47,PRKCE,SLC7A11,TSPAN2,MYC,COPS3,IGF2BP1,TERF2,ADARB1,SYNGAP1,IFNGR2,POLA1,RAPGEF4,RAP1B,PTPN12,ANGPTL4,MTR,DAGLA,SEC31A,CAT,EPRS,ASCC3,ALKBH3,HIF1A,PEX13,DPEP1,MACROD1,MAP2K4,TBKBP1,TRPM2,LTB4R,PDE3A,TERF2IP,ASNS,SLX4,KDM2A,SHC1,UCHL5,VGF,DTNBP1,SOCS6,SERPINH1,RFC4,BRD4,RFC3,PDK1,DLG4,LRRC8A,GNL1,MARCH6,SETD7,POLG2,SERP1,STK10,DCBLD2,SNCA,CAMK2D,MSX2,G6PD,DNAJA3,H2AFX,LARGE,ALKBH1,TRAF3,TBXA2R,XRCC4,MID1,BRAF,NFX1,MLH1,LIAS,OPA1,NOL3,RPS6KA5,FOXO3,GIGYF2,MAD2L2,NEDD4,SFR1,ABL1,TRIAP1,COPS7B,S100A14,EXOSC4,MAP3K14,ERRFI1,YBX3,MBTPS2,PXN,APEX1,KCNMA1,ADSL,APTX,PTK2,OASL,KLF6,POLR2A,SLC23A2,YIF1A,ATM,APAF1,DDIT3,STK4,KAT6A,IMMP2L,NF1,ATRX,PTPRA,KIF5A,FANCD2,RCHY1,PLOD1,SIRT2,SLC29A1,WNT2B,SMARCB1,SRPRB,DST,RAP1A,HYAL1,RELB,POLR3B,NDUFA6,OGG1,LONP1,TRIM14,PRKACB,TRIP13,SRPK2,ZBTB17,TNK2,DEAF1,TRIM13,SIRT6,TFPI,CAV1,COTL1,SOX4,SGK2,CHAF1A,ARPC3,GATA6,CRCP,EME1,CLU,COPS6,TNRC6A,EMSY,FBXO45,FN1,TAF1,PAX2,CDIP1,RHBDD1,DDIT4,CEP164,MCAM,PRF1,ATP6V0D1,KRT20,HBG2,JMJD1C,PSMA1,LIG4,EIF2A,BLOC1S4,ISG15,HERPUD1,ATAD5,MYBBP1A,HK2,RRAGA,SLC16A1,IFITM2,PDE9A,AGO3,RAET1E,BRE,CAMTA2,SOCS1,ITGAX,VCL,C6orf89,AUP1,HTRA2,RTN4RL2,PARP2,GRHL3,EDEM2,RAD54B,HYAL3,ALAD,COPS5,ARNTL,DUSP19,NFRKB,SCARB1,SMG1,TNIK,DNAJC2,DNAJA4,SH2D3A,VPS45,TKFC,BMP6,MRPS11,IL17RE,PRKCH,TANK,STC2,UTS2,RPS6KB2,KDM6B,FGF2,MEN1,PDE2A,HSPA1B,MFN2,GADD45A,DAGLB,CUL2,NFKBIB,POLR1C,ZAK,HRH1 |
| 4.212e-04 | -7.77 | Signaling by TGF-beta Receptor Complex | REACTOME pathways | R-HSA-170834 | 72 | 21 | 8202 | 1117 |
CGN,NCOR2,SMAD7,MEN1,TGFBR2,UBC,SKI,SMAD3,SKIL,FKBP1A,SNW1,PMEPA1,CCNT1,UCHL5,CDK9,MYC,E2F4,RNF111,NCOR1,PARD3,USP15 |
| 4.244e-04 | -7.76 | POLR1D (polymerase (RNA) I polypeptide D) | protein interactions | 51082 | 38 | 14 | 16036 | 2270 |
POLR3D,TSR1,PXN,DDX18,DNAJB6,E2F4,POLR1A,CRCP,POLR1B,POLR3B,POLR1C,NFKBIB,DDIT3,POLR3A |
| 4.248e-04 | -7.76 | V$CREB_Q4 | MSigDB lists | V$CREB_Q4 | 261 | 53 | 17758 | 2279 |
CHMP2A,OXNAD1,CYLD,ID1,BRAF,IFT57,MAP3K13,NF1,PAFAH1B1,ANKRD17,RPS29,OSBPL9,FANCD2,PPP2R2A,RCAN1,CHAC1,RING1,JAG1,SREBF2,INTS7,LETM2,IKBKB,GLYR1,SLC38A2,RELB,JOSD1,PABPC1,CTC1,FGF9,NR6A1,LSM12,SLC38A1,RAB7A,TLE3,ANK2,TEX14,TPM4,LDHA,MRRF,WDHD1,GNL1,SNAP25,MARCH6,NUP214,MBNL2,TMEM175,DDX3X,MSX2,RBBP8,GTF2A1,ZZEF1,VPS37B,SOCS4 |
| 4.279e-04 | -7.76 | RESPONSE_TO_DNA_DAMAGE_STIMULUS | MSigDB lists | RESPONSE_TO_DNA_DAMAGE_STIMULUS | 159 | 36 | 17758 | 2279 |
XPC,ATRX,MLH1,UBR5,RPAIN,ABL1,BRE,TRIAP1,XRCC2,GTF2H1,ATRIP,OGG1,PMS1,RFC3,APEX1,FOXN3,POLA1,LIG4,BRCA1,APTX,RAD54B,RPA1,EXO1,BRCA2,RBBP8,GADD45A,POLE2,RAD51B,MSH3,ATM,ALKBH1,BRCC3,XRCC4,ZAK,MUTYH,DDIT3 |
| 4.358e-04 | -7.74 | ovary-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-small_cell_carcinoma | 125 | 30 | 17775 | 2278 |
BRAF,KMT2D,CYLD,NRAS,ARID2,NF1,ATRX,SETD2,SMARCA4,RNF43,PRDM1,BCOR,ARID1A,MLH1,BRCA1,KMT2C,MEN1,CDC73,FGFR1,SMARCB1,ABL1,BRCA2,SRSF2,SUFU,SOCS1,ATM,KDM5C,RUNX1,MET,MAP2K4 |
| 4.400e-04 | -7.73 | TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS | 37 | 13 | 17758 | 2279 |
METTL1,NSD1,GART,SUV39H2,RNMT,ATIC,PEMT,EHMT1,PCMT1,PRMT5,COQ3,GCSH,CARM1 |
| 4.431e-04 | -7.72 | MSH2 (mutS homolog 2) | protein interactions | 4436 | 114 | 30 | 16036 | 2270 |
SNX27,SART1,PMS1,JUP,POLK,SIRT6,SMARCAD1,SIRT7,FANCD2,BRCA1,MLH1,SUPT5H,AARS,PDE3A,CIAPIN1,RPA1,EXO1,SNW1,SLX4,ANXA7,CDK9,E2F4,MYC,CUL2,MSH3,ATM,ATRIP,NMD3,MUTYH,TRIP13 |
| 4.431e-04 | -7.72 | SKIV2L2 (superkiller viralicidic activity 2-like 2 (S. cerevisiae)) | protein interactions | 23517 | 84 | 24 | 16036 | 2270 |
EXOSC2,MPP6,DROSHA,ZCCHC8,TTC27,ANKMY2,SIRT7,PPP2R2A,NLE1,PABPC4,EIF3H,PUM3,RPA1,SNW1,CWC27,COPS5,UPF2,EXOSC4,YBX3,BMI1,PABPC1,TERF2,SF3A1,CLK2 |
| 4.454e-04 | -7.72 | NAGASHIMA_NRG1_SIGNALING_UP | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_UP | 171 | 38 | 17758 | 2279 |
CYP24A1,SPRED2,ID1,EGR1,SPATA2L,TNFRSF21,JMJD6,TUBB6,BHLHE40,TGFB2,INPP1,PHLDA2,MAP2K3,DST,SOCS1,PMAIP1,MYC,JOSD1,MAP3K14,VCL,TOP1,KDM6B,IFRD1,FERMT2,MCL1,IL6R,PALLD,KLF6,USP36,GADD45A,GATA6,PER1,HIC2,AEN,DLX2,ARC,PDLIM5,DDIT3 |
| 4.463e-04 | -7.71 | RB_P107_DN.V1_DN | MSigDB lists | RB_P107_DN.V1_DN | 125 | 30 | 17758 | 2279 |
BCCIP,KRT7,EIF3C,SIGMAR1,NARS,ELOVL6,PIK3R4,LPCAT3,APTX,CHAC1,AARS,RSRC1,LPAR3,TARS,S100A16,DDIT4,POLR3G,PGD,RDH11,ANXA1,RHOU,RARS,NME7,COQ9,CBR4,GSTA4,TXN2,POLR1E,HSD17B12,NIPSNAP1 |
| 4.463e-04 | -7.71 | ZHU_CMV_ALL_DN | MSigDB lists | ZHU_CMV_ALL_DN | 125 | 30 | 17758 | 2279 |
LAMA4,LAMC1,COL5A2,ACTG1,XPC,PAFAH1B1,TFPI,TPM4,DDR2,ID2,MYH9,ZFP36L1,AARS,TCF7L2,DDIT4,PYCR1,ANXA1,CHN1,ABL1,ANAPC1,TP53BP1,VCAN,CFD,TNFRSF1A,C7orf50,BMP4,RUNX1,NR2F2,TPM1,PABPC1 |
| 4.465e-04 | -7.71 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | MSigDB lists | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 71 | 20 | 17758 | 2279 |
PHLDB2,DNM3,SH2D3A,TFPI,IGF2BP2,ENC1,ANGPTL4,VDR,SRCAP,DSC2,PTRF,HK2,HSPB8,SLC4A7,ADAM9,MET,CD44,MGLL,LYST,NT5E |
| 4.470e-04 | -7.71 | MODULE_52 | MSigDB lists | MODULE_52 | 420 | 78 | 17758 | 2279 |
RIBC2,SLC2A1,CSNK2A1,GYG1,RAC3,BIRC2,ASNS,SRSF2,AP1M1,WIZ,SERPINH1,PEG10,MGLL,OGG1,HTRA2,TRIP13,PRPF19,DBN1,RFC4,PRAME,COL5A2,KRT7,ITPA,AKAP12,CAV1,SOX4,MCM2,DSP,FGFR1,CHAF1A,PLIN2,HPRT1,INSIG1,PER1,H2AFX,ADAM9,SEMA3C,ANXA2,TPM1,NOLC1,TMEM158,RBP1,AK2,MCM6,FN1,ST6GAL1,UBXN1,PDE4B,ARFIP2,ZIC2,TGFBR2,PHLDA2,ETFB,DDIT4,IGF2BP3,GART,SLC7A11,PTRF,MYC,COPS3,MFAP2,CAV2,SERBP1,FADS1,MSX1,CRIM1,MYO10,ADSL,ARID1A,GPNMB,ISG15,ANXA1,SYNCRIP,FAT1,FDPS,SVIL,UMPS,DDIT3 |
| 4.489e-04 | -7.71 | regulation of mRNA 3'-end processing | biological process | GO:0031440 | 28 | 11 | 16441 | 2138 |
PAF1,RNF40,CCNT1,CDK9,AGO2,CTR9,NCBP2,SUPT5H,AHCYL1,CDC73,PABPC1 |
| 4.542e-04 | -7.70 | DDX23 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 23) | protein interactions | 9416 | 65 | 20 | 16036 | 2270 |
SART1,THOC5,CUL7,PAXBP1,PRPF31,TFIP11,SIRT7,SF3A3,BRCA1,PIP4K2A,RSRC1,RPA1,TERF2IP,SNW1,PHF5A,BCAS2,HNRNPR,PRPF4,CPSF3,TOP1 |
| 4.568e-04 | -7.69 | SMC3 (structural maintenance of chromosomes 3) | protein interactions | 9126 | 99 | 27 | 16036 | 2270 |
PMS1,CAMKK2,FEZ2,CUL7,STAG1,SIRT6,SMARCAD1,CDK4,SMARCA4,HDAC8,BRCA1,SUPT5H,POLR2A,RPA1,BRCA2,NEK6,SSU72,NSMCE2,COPS5,CUL2,PDS5B,ATM,RNF2,CEP63,COPS6,HNRNPM,TERF2 |
| 4.568e-04 | -7.69 | G3BP1 (GTPase activating protein (SH3 domain) binding protein 1) | protein interactions | 10146 | 99 | 27 | 16036 | 2270 |
WDR36,EIF3C,FN1,SIRT6,SIRT7,TPM4,NOL6,USP10,ADSL,NUP214,GIGYF2,PABPC4,FLNB,UBC,ISG15,CLNS1A,RIOK2,KRI1,POP1,ASCC3,COPS5,RNF2,EIF2B3,NOLC1,BMI1,PABPC1,RPS6KB2 |
| 4.569e-04 | -7.69 | LOC101060521 (DNA-directed RNA polymerase III subunit RPC5) | protein interactions | 101060521 | 9 | 6 | 16036 | 2270 |
CRCP,BCCIP,POLR3D,POLR3B,POLR3A,POLR3G |
| 4.588e-04 | -7.69 | GGCKCATGS_UNKNOWN | MSigDB lists | GGCKCATGS_UNKNOWN | 61 | 18 | 17758 | 2279 |
ZBTB17,GON4L,NF1,PAX2,RDH10,VSNL1,SMAD7,RSF1,CORO6,PRPF39,PTPN2,ZFAND3,RBBP8,JAG1,INTS7,HK2,TRMT2A,ZMYM2 |
| 4.588e-04 | -7.69 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | 61 | 18 | 17758 | 2279 |
DMGDH,SESN2,ALDH1L2,SETD7,PHGDH,TBC1D16,WARS,TRIB3,MTHFD2,ASNS,SLC7A11,KLF4,STC2,CTAGE5,DNAJC12,CORO1A,PCK2,RBP1 |
| 4.592e-04 | -7.69 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | 268 | 54 | 17758 | 2279 |
SRM,GGT1,RHOBTB1,CLK1,SEC24D,ST6GAL1,ALG8,CHAC1,BHLHE40,ST3GAL6,MBNL1,HSPA1A,DDIT4,IGF2BP3,IQGAP2,ZNF804A,DST,C6orf48,SLC7A11,LRP2BP,FMNL1,MYC,SUCLG2,SHMT2,ANP32B,SERPINH1,AVEN,LONP1,MYB,IFRD1,SLC3A2,ATF4,PDK1,PSAT1,SLC38A1,JMJD1C,SUMO3,PHACTR2,MARCH6,IL6R,PDE3B,HERPUD1,UBE2E1,HSPA1B,TIMM44,TRIB3,PXDN,GADD45A,POLR3E,MYOM2,TNFRSF10D,ZNF532,DDIT3,LRRC41 |
| 4.601e-04 | -7.68 | GSE17721_0.5H_VS_4H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_4H_LPS_BMDM_UP | 189 | 41 | 17758 | 2279 |
SLC2A1,SSBP2,SEC16A,PAG1,FRRS1,NDUFB3,RAP1A,ARMC6,DTNBP1,CTR9,POLE3,ANP32B,TMEM14C,NUDC,VOPP1,CRADD,HARS,RAB7A,ELOVL6,LDHA,RNH1,MCM2,EVI5,SLC50A1,ABCF1,NEU1,MRPL36,STOML2,MGAT2,KLHL22,HELZ,NSF,ORC5,H2AFX,CRCP,PTP4A2,TXN2,ECHDC1,SYNPO,IPO4,TMEM33 |
| 4.601e-04 | -7.68 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN | 189 | 41 | 17758 | 2279 |
BANP,ASCC1,LYRM4,CCDC58,LIN28B,UTP14A,CCDC53,OLA1,FARS2,PLA2G12A,POP5,MAN1A1,DCTPP1,ADH5,NUBPL,BCAS2,PSMG4,SOCS1,ATG3,BANF1,MRPL21,ZNRD1,LSM10,CAV2,TIMM8B,EVL,NPM3,ALDH1L2,MED27,GRHL3,PSMG1,C19orf70,MRPL36,GSTO2,SSU72,ALAD,RRAGA,PTRH2,FIS1,NFKBIB,PDSS2 |
| 4.622e-04 | -7.68 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN | 195 | 42 | 17758 | 2279 |
SRM,CARS,POLR1A,OLA1,JMJD6,CHCHD10,RNASEH2B,DCTPP1,CAD,DECR1,IDI1,NVL,MCM5,PDS5B,ALDH18A1,PPA1,TRIP13,CARM1,ELOF1,RFC4,PRIM2,DDX41,MINA,MRPS10,BRCA1,MCM2,CYB5B,TRIM37,TAMM41,TPD52L2,MTHFD2,LUC7L3,SYNGR2,HK2,CRCP,NCBP2,NDUFS5,RBPJ,HMBS,DHCR7,BLMH,GCSH |
| 4.622e-04 | -7.68 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | 195 | 42 | 17758 | 2279 |
SLC12A7,WDR75,SPRED2,XPC,WDR74,FAM189B,TTC27,POLR1A,ST6GAL1,HSD17B10,CCNL2,NOP56,DDIT4,FARSA,CD96,AMPD3,UBE3A,SURF2,SOCS1,NOP16,TTC3,TERF2,CLK2,HMBOX1,EVL,PDK1,AKAP8L,BAZ2A,GNL3,ELOVL6,SHISA5,POLG2,STK10,UBR4,RERE,NSMCE1,FAM114A2,ARNTL,MDN1,POLR1C,XPO6,IPO4 |
| 4.625e-04 | -7.68 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 673 | 116 | 17775 | 2278 |
CHMP2A,BIRC6,UPK3B,URB2,PTPRA,PDK4,DDR2,TRPM6,CSNK2A1,RIPK1,STK33,PRKCA,MAP2K3,RIOK2,RTN1,ABL2,FLAD1,ANKRD13A,ANAPC1,PRKD3,SRSF2,BRE,SREBF2,CCDC50,NEK6,ATG3,RPS6KL1,IKBKB,ADCK4,MET,SRRM2,CDK12,CDK6,LONP1,PRKACB,SRPK2,ZCCHC14,TNK2,NRAS,BRD4,PDK1,SFSWAP,CDK4,ANK2,AP4B1,NOL6,KSR2,LAMA2,SGK2,SON,TBC1D16,STK10,FGFR1,TJAP1,DYRK1B,CAMK2D,TRRAP,HIPK2,SGSM2,CSMD3,RPS6KB1,RIOK1,MDN1,TSEN2,WDR66,SMG1,TNIK,BCKDK,SSH2,BRAF,SULT1C2,TAF1,MAP3K13,SUPT6H,CLK1,CAMK1,TRIO,PIK3R4,ATG2B,TGFBR2,CSNK1A1,FOXO3,FAM49A,ABL1,PRKCE,PRKCH,SIPA1L3,ASAP1,SCAF1,PDE10A,PVRL3,MAP3K12,PABPC1,RPS6KB2,CLK2,SIK3,CAMKK2,TEX14,OBSCN,C19orf70,MTR,OXSR1,DYNC1H1,TRIB3,ZZEF1,SNAP23,SRD5A3,RIOK3,GPN1,ATM,RPS6KC1,TBCK,KIF1B,ZAK,MAP2K4,STK4 |
| 4.634e-04 | -7.68 | oesophagus | COSMIC cancer mutations | oesophagus | 15768 | 2067 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,THAP4,LETM2,MAD1L1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,ZNF710,ACTR3B,C15orf41,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,DYRK1B,HPRT1,TCF7L1,ADAM9,TSEN2,MAGI1,USP15,FOXO1,ITFG1,FAN1,ZIC2,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,HM13,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,SUCLG2,CSGALNACT2,ACADS,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,ABL1,NEBL,SDCBP2,NAV3,TMC7,SLC40A1,TTLL5,TMEM126B,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,PDE9A,DMXL2,TCF12,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RRN3,SOCS1,PPFIBP1,SNTG2,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,CRIM1,SULT4A1,SCMH1,ZNF324B,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,HRG,AVEN,CNTNAP3B,PLEKHM3,DCUN1D5,C10orf76,RBM28,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,PRKD3,ERI1,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,ZNF467,PDE3B,FOXC1,CASC1,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,ETV1,MPST,PTPRK,SF3A1,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,PELP1,CAD,UBR1,ARMC5,FSIP2,C15orf40,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,ZNF561,ANXA7,IFIT5,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,MYCBP2,POLB,PRDX6,TNFRSF21,ADAMTS6,GIPR,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,FOSL2,LTB4R,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,BBIP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,ETFB,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,TMLHE,HN1,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ADNP,COPS5,SRFBP1,DISP1,SCARB1,HEATR1,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,AMOT,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,LYST,EIF3J,PI4KAP2,ZNF480,SLCO6A1,PCNXL2,CCNDBP1,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CATSPERG,RAB30,SHQ1,TRIM22,IP6K2,PSMF1,SNW1,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,ERVMER34-1,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,LAMA2,KCNH2,LSG1,BSN,C1orf122,CXADR,LSS,CHD3,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,MLX,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SART1,MPI,OLFM2,NDUFAF2,RPS29,RIPK1,SSBP2,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,CPNE7,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,PLAC8L1,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,RFXAP,CADM4,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,SMARCC1,G6PD,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,CRCP,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,UBXN1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,TBCK,FNBP1L,N4BP2L2,CHMP2A,FEZ2,PSTPIP2,TNXB,TBCCD1,TMEM177,SPATS2,DHX35,ZC3H13,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,MRRF,POU2F1,DKC1,UBR4,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,FAAH2,RABGAP1L,RASSF3,C12orf76,WIZ,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,PACRGL,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,GTF2H3,BDNF,TIMM8B,COL17A1,PRDM16,EPS15L1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,DNM3,ZNF516,TRERF1,BTBD2,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,PES1,TAF2,GNG2,IQCH,WDR7,FUS,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,SF3A3,JMJD6,AKT1S1,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,DIS3L2,ULBP1,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,R3HDM2,UBE2K,DDX49,RPA1,TRIB3,RARS,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,TNFRSF1A,SOCS4,DLX2,CHMP4C,SEPHS2,NOMO3,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HES6,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,PPIL2,SAMD11,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,CRADD,LAMC1,TLE3,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,TMEM123,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,CWC27,SELT,DDX31,PCK2,FBXO31,FAM71E1,ZMYM5,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,SRBD1,GPC2,TMEM237,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,FUT11,DPF3,SLC38A6,EYA3,NOL8,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,FAM118A,TXN2,ZNF598,PTPN14,WDR75,IFT57,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,SCAF11,ADARB1,SYNGAP1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,RIBC2,URB2,ZBTB37,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,TERF2IP,PHC2,ZNF827,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,PFKFB4,FAM120B,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,STK4,LRRC41,TRPM6,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,SH2D3A,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 4.675e-04 | -7.67 | positive regulation of DNA-templated transcription, elongation | biological process | GO:0032786 | 24 | 10 | 16441 | 2138 |
PAF1,ELL,THOC5,BRD4,SUPT4H1,WDR61,SUPT6H,CTR9,SUPT5H,CDC73 |
| 4.702e-04 | -7.66 | tibia | COSMIC cancer mutations | tibia | 871 | 145 | 17775 | 2278 |
SLC37A3,MYCBP2,ZNF76,THOC5,ACTG1,CNTNAP3,NAT10,RNF43,CSPP1,BCOR,HMOX2,CIAPIN1,ZNF804A,DST,CHD2,POLR3B,SRRM2,ETV1,FLNC,DTNB,DPF3,GPM6A,OSBP2,ABCC4,MED27,GPCPD1,RFX2,KSR2,LAMA2,KCNH2,SON,VPS13D,MAGI1,NMD3,SLC12A7,HERC2,CARS,C9orf78,TMEM63C,ZHX3,ITPRIP,PAX2,TRIO,DNAH1,MTUS1,RSPRY1,MCAM,ZCCHC7,MAP3K12,SAMD3,HMGCR,KLRD1,IFRD1,CRADD,TSTA3,MYO10,OBSCN,ST6GALNAC3,PLCB1,ATP9B,DAGLA,EPRS,LRP1B,FAM135A,MYBBP1A,FAT1,SNAP23,EXOC4,PFDN2,C12orf45,COG5,DMXL2,NDUFAF2,TMEM183A,RIPK1,ZNF83,DENND3,ZC3H13,PHC2,CCDC50,KDM2A,NUP133,RPS6KL1,ZNF142,BCAP29,GSTA4,MTHFD2L,ZC3H3,LYST,KMT2D,R3HDM1,ATXN1,EDEM2,DSP,UBR4,RAB10,BAZ1A,LMBR1L,KDM4B,SMARCC1,KPNA3,FTSJ1,INTS9,SCARB1,BRD9,LAMA5,SMG1,BCKDK,TNIK,BRAF,RFX1,ZNF280C,SLC25A12,CLSTN2,ATG2B,ATF7IP,NEDD4,FAM50A,PVRL3,DDX31,POLR1B,ZNF710,PKNOX1,FAM120B,TSHZ1,ADAMTSL3,PALLD,NAALADL2,CHCHD6,POLR3A,CCDC150,SMPDL3B,RARS,PXDN,ALG5,ACOX1,VPS37B,CSRNP1,MSH3,ATM,APAF1,XPO6,MIPOL1,IPO4,KDM4C |
| 4.738e-04 | -7.65 | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | MSigDB lists | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | 572 | 101 | 17758 | 2279 |
DLL4,TRPM2,LUZP1,PAFAH1B1,KIF5A,PDK4,KLHL18,COBLL1,ENAH,RNF43,CHAC1,STK33,SYNJ1,MAP2K3,AHCYL2,ZKSCAN1,ARMC5,C12orf76,SOCS6,RNF111,BCAP29,LYRM5,ZMYM2,LYST,SEH1L,CARM1,SOBP,TUBA1A,BAZ2A,ANK2,ATF7IP2,PCMT1,SUMO3,SATB2,SON,RAB10,DHX57,DCBLD2,SMAD3,DDX3X,ZNF622,CC2D1B,ITGA2,HOXA3,SLC4A7,GREB1L,DCAF5,TSPAN5,DMTF1,ZNF532,TMCC1,TMEM33,USP15,MINK1,CDC42EP2,ZHX3,KLC4,SMAD7,PID1,CHD5,POM121,IL17RE,ELL,NAV1,NEBL,PI4KB,ATXN2,SEMA3D,COPS7B,AKAP11,SERBP1,LYPLA2,MYB,BDNF,LAMC1,ADAMTSL3,FGF2,CRIM1,SIGMAR1,USP42,FERMT2,RSBN1,MAPK1IP1L,ARID1A,CACNB1,LRP1B,HELZ,UBAP1,STX1A,SPEN,ACOX1,CUL2,RNF138,TBPL1,GPN1,PURB,PEX13,ARHGAP12,PDLIM5,MIPOL1,KIF1B |
| 4.763e-04 | -7.65 | purine nucleotide metabolic process | biological process | GO:0006163 | 327 | 64 | 16441 | 2138 |
NDUFA5,ATP6V1A,NDUFB5,OLA1,COX10,HSPA1A,PDE3A,NDUFB3,AMPD3,ATP5G2,PPCDC,MYH3,NT5C,FHIT,NDUFA6,FXN,MTHFD2L,OGG1,MCEE,ITPA,DLG4,ATP6V0A1,NUDT15,PDE8B,SNCA,STOML2,ATP5D,HPRT1,MUTYH,AK2,SULT1C2,PDE4B,CHCHD10,APRT,NDUFS7,NDUFV1,GART,ENTPD5,ATIC,PDE10A,PRPS1,HMGCR,MTHFD1,NT5E,PFKFB4,BDNF,PDE4A,PPAT,LDHA,SULT4A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,CAT,NME7,COQ9,SURF1,HK2,BPNT1,NDUFS5,ADK,PDE9A |
| 4.773e-04 | -7.65 | negative regulation of chromosome organization | biological process | GO:2001251 | 102 | 26 | 16441 | 2138 |
SUPT6H,KDM5A,TEX14,CSNK2A1,BCOR,BRCA1,UBR5,MAD2L2,KDM1A,UBE2E1,SKI,SNCA,SMARCB1,TERF2IP,ANAPC1,KLHL22,CDC16,ACD,ANAPC11,SET,ANAPC10,ATG7,MAD1L1,ATM,ANAPC4,TERF2 |
| 4.784e-04 | -7.65 | adherens junction | cellular component | GO:0005912 | 471 | 85 | 17570 | 2233 |
ARHGAP26,ACTG1,ACTR3,RPS29,DDR2,MYH9,CD99L2,ENAH,GIT2,HSPA1A,FLNB,DST,ESAM,RPS16,JAG1,PPFIBP1,MMP14,VCL,PTPRK,FLNC,PHLDB2,TNK2,EVL,LIMA1,PTPRM,HSPA5,AKAP12,VIM,CAV1,DSP,NUP214,RAB10,CXADR,ARPC3,RHOU,AHNAK,MISP,ITGA2,DPP4,ADAM9,NFASC,MAGI1,NRP1,PARD3,LPP,CADM4,EFNB2,JUP,TRIP6,NHS,LAMTOR3,SMAD7,CD226,MCAM,PVRL3,ANXA5,RDX,CD44,PABPC1,PNMA1,CAV2,SPTAN1,PPP1R9B,PXN,TPM4,ASAP3,FERMT2,ATAT1,PTPN12,LIG4,PTK2,PALLD,PEAK1,ANXA1,HSPA1B,CAT,PDLIM1,MPP7,SRP68,FAT1,SNAP23,ADGRE5,CASS4,SVIL,PRKAR2A |
| 4.793e-04 | -7.64 | ACTN1 (actinin, alpha 1) | protein interactions | 87 | 130 | 33 | 16036 | 2270 |
TTN,EPM2AIP1,CUL7,SIRT7,SF3A3,GIT2,AMBRA1,NEBL,ATXN2,GTF2H1,MYH15,KDM5C,VCL,FXN,TERF2,DDN,COL17A1,TUBA1A,SIRT6,TPM4,PSMA1,PTK2,PALLD,ISG15,ATXN7,PDLIM1,SVIL,CLU,TPM1,XRCC4,PDLIM5,BMI1,LPP |
| 4.796e-04 | -7.64 | TAF6 (TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa) | protein interactions | 6878 | 56 | 18 | 16036 | 2270 |
TAF1,SETD7,SUPT5H,TAF9B,SMARCB1,TAF2,TRRAP,SMARCC1,GTF2A1,TAF3,CHD3,TAF4,TBPL1,RAN,NCOR1,TAF12,KMT2A,SAP30 |
| 4.878e-04 | -7.63 | DAZARD_RESPONSE_TO_UV_SCC_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_DN | 120 | 29 | 17758 | 2279 |
HMGA2,PHF3,ID1,SLK,RAP1GAP2,MCL1,ISG20L2,SLC25A44,SOX4,TGFBR2,FOXO3,POGZ,DDIT4,SPOP,PHC2,SACS,BAZ2B,MPHOSPH10,KDM2A,NOP16,ADNP,MYC,TNFRSF1A,RBPJ,CNOT4,SGSM3,KAT6A,NAV3,HMGCR |
| 4.882e-04 | -7.62 | TNF-alpha/NF-kB Signaling Pathway | WikiPathways | WP231 | 194 | 41 | 4455 | 564 |
CYLD,MAP2K5,POLR1A,DPF2,FANCD2,SMARCA4,RIPK1,CSNK2A1,IKBKAP,RPS6KA5,BIRC2,IQGAP2,SMARCB1,COPS3,MCM5,TANK,IKBKB,RELB,POLR1B,FBL,MAP3K14,POLR1E,CASP10,CASP8AP2,CDC37,CRADD,MTIF2,PTK2,CAV1,DDX3X,SMARCC1,KPNA3,GLG1,TNFRSF1A,TRAF3,RPS6KB1,FKBP5,PFDN2,NFKBIB,POLR1C,USP11 |
| 4.948e-04 | -7.61 | MORF_GNB1 | MSigDB lists | MORF_GNB1 | 300 | 59 | 17758 | 2279 |
NCOR2,MCM6,AK2,PRPF31,KHDRBS1,PTPRA,DDX19A,ACTR3,TRAK1,RTN4,XPO7,POM121,PABPC4,NDUFV1,SRSF2,SREBF2,SEC24C,TNPO3,SSBP1,AHCYL1,YARS,GNG5,HNRNPM,NUDC,SF3A1,IFRD1,CAMKK2,GARS,ATF4,BAZ2A,SKIV2L2,IDH3G,PCMT1,R3HDM1,PSMA1,TMEM123,DKC1,MCM2,DDX49,SERP1,TARS,EIF3H,ARIH2,POLR2A,ARPC3,EPRS,CDC16,SMARCC1,HNRNPR,TIMM17A,SET,GPN1,ACP1,NDUFS5,PTP4A2,BMI1,TROVE2,SRP14,XPO6 |
| 4.957e-04 | -7.61 | V$MYCMAX_03 | MSigDB lists | V$MYCMAX_03 | 238 | 49 | 17758 | 2279 |
CHST11,OLFM2,CELSR3,UTP14A,ANKRD17,DYM,NFX1,TGFB2,RLF,FOXO3,BMP6,GIGYF2,PABPC4,RSPRY1,FAM192A,SLC38A5,DCTN4,SLC38A2,RELB,IGF2BP1,CELF1,ZCCHC7,FBXL19,PRPS1,PABPC1,ATF4,SIGMAR1,MCM2,KRTCAP2,TRIM37,ODC1,CPT1A,NOP58,MAT2A,RPA1,DDX3X,SYNCRIP,GTF2A1,ZBTB8OS,PER1,VPS37B,CTAGE5,DLX2,EME1,PFDN2,RAB30,KAT6A,USP15,NIT1 |
| 5.048e-04 | -7.59 | mRNA binding | molecular function | GO:0003729 | 140 | 33 | 16491 | 2164 |
AUH,RBFOX2,DCP1B,AGO2,ZFP36L1,IGF2BP2,PARN,HNRNPA3,HNRNPLL,EDC3,PAIP2,MRPS11,IGF2BP3,RNF40,NSRP1,MBD2,CELF1,IGF2BP1,YBX3,SERBP1,ADARB1,PTBP2,TSN,XPO5,PUM3,DDX3X,IREB2,EIF4ENIF1,EEFSEC,LUC7L3,PURB,NCBP2,NOCT |
| 5.071e-04 | -7.59 | REACTOME_PURINE_METABOLISM | MSigDB lists | REACTOME_PURINE_METABOLISM | 33 | 12 | 17758 | 2279 |
CAT,HPRT1,AMPD3,GART,PPAT,ATIC,ADSL,APRT,NT5C,IMPDH2,ADK,NT5E |
| 5.082e-04 | -7.58 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | 178 | 39 | 17758 | 2279 |
SLC12A7,PTP4A1,TTN,C9orf78,ITPRIP,FOSL2,MTUS1,CNST,USPL1,POLR3B,FHIT,KIAA0922,NRIP1,CDK12,NOM1,IL11RA,RAP1GAP2,TBXAS1,TCEB3,CUX1,PCNXL2,EXOG,ENC1,SLC26A11,TCF7L2,ANXA1,NAP1L5,SKIL,NSD1,ARHGAP21,TOE1,ZDHHC11,AHNAK,MPP7,KLF4,POLR3E,AEN,RIOK1,FIS1 |
| 5.085e-04 | -7.58 | HALLMARK_DNA_REPAIR | MSigDB lists | HALLMARK_DNA_REPAIR | 143 | 33 | 17758 | 2279 |
POLB,XPC,PDE4B,NFX1,SF3A3,APRT,SNAPC4,POM121,ELL,DCTN4,GTF2H1,NT5C,ZNRD1,SNAPC5,RFC4,GTF2H3,RFC3,ITPA,RNMT,POLA1,TCEB3,IMPDH2,SUPT5H,POLR2A,HPRT1,SUPT4H1,VPS37B,SURF1,UMPS,NCBP2,TAF12,USP11,POLR1C |
| 5.085e-04 | -7.58 | SMITH_TERT_TARGETS_UP | MSigDB lists | SMITH_TERT_TARGETS_UP | 143 | 33 | 17758 | 2279 |
XPC,SMAD7,PIGH,NFX1,PPP2R2A,MLH1,AARS,RPP30,SNW1,ASNS,SHMT2,JOSD1,KDM5C,TOMM34,TOP1,IFRD1,FGF2,CDK4,HSPA5,FERMT2,R3HDM1,MARS,HERPUD1,PYCR1,MTHFD2,GATA6,G6PD,CCDC85B,CTAGE5,INTS9,EIF2S1,ALKBH1,DDX10 |
| 5.124e-04 | -7.58 | purine-containing compound metabolic process | biological process | GO:0072521 | 372 | 71 | 16441 | 2138 |
NDUFA5,ATP6V1A,NDUFB5,OLA1,COX10,HSPA1A,AHCYL2,PDE3A,NDUFB3,AMPD3,ATP5G2,MYH3,PPCDC,NT5C,FHIT,NDUFA6,AHCYL1,FXN,MTHFD2L,OGG1,MCEE,ITPA,DLG4,ATP6V0A1,NUDT15,MAT2A,PDE8B,ATP5D,STOML2,SNCA,HPRT1,PEMT,MUTYH,AK2,SULT1C2,MRI1,PDE4B,CHCHD10,APRT,NDUFS7,GART,NDUFV1,ENTPD5,ATIC,PDE10A,SLC16A9,PRPS1,HMGCR,MTHFD1,NT5E,PFKFB4,BDNF,PDE4A,PPAT,LDHA,SULT4A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,CAT,NME7,COQ9,HK2,SURF1,BPNT1,NDUFS5,MACROD1,ADK,PDE9A |
| 5.125e-04 | -7.58 | NEGATIVE_REGULATION_OF_TRANSCRIPTION | MSigDB lists | NEGATIVE_REGULATION_OF_TRANSCRIPTION | 184 | 40 | 17758 | 2279 |
ZNF254,ID1,ZHX3,RBFOX2,KHDRBS1,NFX1,ID2,ATF7IP,BCOR,SIRT2,RSF1,SNW1,VPS72,JAZF1,TIMELESS,ZEB1,ZNF148,NRIP1,KAT8,KDM5B,NR6A1,FOXN3,ARID5B,CUX1,ATXN1,POU2F1,HDAC8,PRDM1,BRCA1,MEN1,SUPT5H,VDR,SMAD3,NSD1,SUPT4H1,KLF4,PER1,TBX3,RBPJ,KAT6A |
| 5.125e-04 | -7.58 | GSE3982_EOSINOPHIL_VS_BCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BCELL_DN | 184 | 40 | 17758 | 2279 |
LARS2,TCF3,SMARCA4,PARN,REEP5,ETFB,KDM1A,FDX1,MRPS30,CAD,RRN3,RPS16,ASNS,SREBF2,NVL,NUP133,SUCLG2,SHMT2,PRMT5,FBL,HTRA2,PERP,NT5E,NIPSNAP1,DNMBP,WDR61,ABCF2,USP10,ZDHHC14,DHX57,RERE,STOML2,PWP1,MYBBP1A,MPV17,EIF2S1,ZNF32,UMPS,KLHDC4,BLMH |
| 5.125e-04 | -7.58 | V$MAZ_Q6 | MSigDB lists | V$MAZ_Q6 | 184 | 40 | 17758 | 2279 |
FAM189B,SLC2A1,TMEM109,ARFIP2,PBX1,SMG7,GABPB2,POGZ,PHC2,SHC1,WAC,GTF2H1,ZEB1,UPF2,RNF2,CELF1,YARS,ZBTB17,LRRC20,RTN4RL2,BDNF,NRAS,SESN2,PRDM16,POU2F1,TOR1AIP2,ARID1A,KRTCAP2,UBR4,TCF7L2,NCDN,RERE,MLLT10,DDX50,AHNAK,HNRNPR,CUL2,FDPS,FNBP1L,ATXN7L2 |
| 5.125e-04 | -7.58 | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | 184 | 40 | 17758 | 2279 |
SLC37A3,TCF12,FEM1C,ATP6V1A,TRIO,DBF4,PDE4B,WDR37,MBNL1,FAM8A1,C15orf57,PIP4K2A,MAN1A1,RABGAP1L,PAK1IP1,ERRFI1,TOP1,NT5E,VOPP1,CHD9,SIK3,GPHN,AP4S1,EXOC6B,CPOX,JMJD1C,ARID5B,ARHGEF10,PSMA1,AKAP13,KLF6,EVI5,ZBTB25,TASP1,L3MBTL3,HIF1A,NSMCE2,ARL4A,PPP3CC,LRCH1 |
| 5.153e-04 | -7.57 | TGTGTGA,MIR-377 | MSigDB lists | TGTGTGA,MIR-377 | 190 | 41 | 17758 | 2279 |
PHF3,CUL4A,EGR1,DLGAP4,ZFP36L1,SLC6A8,ARID1B,C15orf57,RPGRIP1L,ATXN7L1,JAG1,THADA,JAZF1,GLYR1,NBEA,SLC35C2,SRPK2,ADARB1,FLNC,HMBOX1,LAMC1,SSFA2,NR6A1,BAZ2A,TEAD1,FOXN3,AGPAT4,KCNMA1,ATXN1,RSBN1,ARID1A,ZDHHC14,PLCB1,PHF6,ATXN7,ARHGAP21,BAZ2B,RPS6KB1,FNBP1L,MMP16,HS2ST1 |
| 5.153e-04 | -7.57 | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | MSigDB lists | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | 190 | 41 | 17758 | 2279 |
SRM,FN1,CCDC58,WDR74,PRPF31,B4GALT5,POP5,NUP43,GAS6,RBM19,UBTD2,MFHAS1,SLC39A1,SACS,S100A10,PYCRL,MET,HSD17B12,ADARB1,NAA38,TRIM13,WDR61,CDK4,GNL3,ZFP14,LGALS1,PRDM1,TARS,FGFR1,TMEM186,TAF9B,POP1,HIF1A,DNAJA3,IRAK2,SET,CSRNP1,HOXA3,SQLE,NFKBIB,NOLC1 |
| 5.153e-04 | -7.57 | GSE27786_NKTCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKTCELL_VS_NEUTROPHIL_UP | 190 | 41 | 17758 | 2279 |
SART1,PCNT,PPP2R2A,SF3A3,TBCCD1,TMEM177,FAM122B,PRPF39,UBE3A,ARHGAP18,THADA,UBR1,COPS3,PPIL2,ANAPC10,KDELC1,FAM98A,DDX28,AEBP2,DDX24,PARP2,FRA10AC1,SCFD2,METTL15,ADSL,ODC1,NUP214,PHF6,ZNF708,LUC7L3,ITGA2,ARNTL,ALKBH1,PTPN4,ZFP90,MDN1,TBL1X,CNDP2,TXN2,ZNF598,DCAF5 |
| 5.154e-04 | -7.57 | HIST1H4A (histone cluster 1, H4a) | protein interactions | 8359 | 141 | 35 | 16036 | 2270 |
CARS,NCOR2,MCM6,CUL7,FN1,TAF1,SIRT7,JMJD6,XPO7,PELP1,TTC1,UCHL5,MCM5,HIRIP3,ANP32B,PRMT5,KMT2A,PRMT3,GATAD2B,KAT8,BRD4,GARS,BAZ2A,ELP3,HDAC8,MCM2,SETD7,TP53BP1,COPS5,CUL2,H2AFX,NCOR1,TBL1X,TROVE2,KAT6A |
| 5.164e-04 | -7.57 | ACEVEDO_LIVER_CANCER_UP | MSigDB lists | ACEVEDO_LIVER_CANCER_UP | 913 | 151 | 17758 | 2279 |
PTP4A1,PHF3,PRKAB2,TFIP11,WDR13,TMEM109,CIAPIN1,TOM1L1,S100A10,COPS4,MARVELD2,NCKIPSD,ANAPC10,AVEN,NRAS,FAM127A,NFIA,GMFB,PSMG1,SLC50A1,SH3GL1,PEX1,YTHDF2,TMCO1,EIF4ENIF1,MPV17,FIP1L1,BMI1,NMD3,DMTF1,DROSHA,ITFG1,KHDRBS1,STXBP6,SIRT7,LAMTOR3,ZFP36L1,PDCD7,TIMM10,TOX4,FAM192A,SUB1,CCDC167,NOC3L,CWF19L2,NT5E,VOPP1,RANBP6,ALG6,ANAPC13,RB1CC1,PTPN12,RNH1,ZNFX1,TBC1D2,EPRS,KIDINS220,SRRD,FAT1,IRAK2,ARHGAP12,C7orf50,KIAA0196,TBCK,SMYD3,NR2C2AP,ATP6V1A,TMEM183A,ACTR3,NDUFB5,HSPA1A,DHX35,SBDS,IDI1,LYPLAL1,NUP133,PPID,UCHL5,GSTA4,SERPINH1,MET,TSPAN14,CDK12,GNG5,TMEM14C,HN1,C18orf21,KDM3B,RFC4,PTBP2,TUBA1A,ATXN1,VIM,PNN,EDEM2,SERP1,EIF3H,WARS,CDC16,KPNA3,SMARCC1,HNRNPR,NSMCE2,POLR3E,ABHD3,H2AFX,ACP1,FKBP5,HEATR1,DISP1,YEATS2,COMMD10,AUH,MIF4GD,TTC27,VPS45,FARS2,MYNN,WDR26,TRIM22,BZW2,RSRC1,RMI1,PRKCH,CWC27,NISCH,DCTN4,LTN1,HARS2,RDX,CLDND1,EXOSC4,FAM98A,KDM5B,TMEM126B,ANKMY2,MARS,ZNF467,PALLD,C8orf33,FOXC1,HSPA1B,ZDHHC11,HNRNPH3,NCBP2,TAF12,APAF1,PREPL,TATDN1,IGBP1,IPO4 |
| 5.195e-04 | -7.56 | YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta) | protein interactions | 7534 | 337 | 70 | 16036 | 2270 |
CUL7,MAP2K5,KIAA0232,OLA1,MYH9,PRKCA,HSPA1A,PABPC4,EDC3,SYN2,UCHL5,RMDN3,VCL,LYST,KAT8,BRD4,SSFA2,TCEB3,ATXN1,VIM,BRCA1,AKAP13,CHAF1A,SH3GL1,EXO1,TP53BP1,G6PD,COPS5,H2AFX,FUS,TBXA2R,NOLC1,SYNPO,PTPN14,MAPT,PARD3,MEF2C,SSH2,MINK1,BRAF,FOXO1,FN1,SLK,KLC4,FAN1,NKD2,CEP126,AKT1S1,RPS6KA5,CSNK1A1,FOXO3,DDIT4,ABL1,PRKCE,UBE3A,SHMT2,PRMT5,ERRFI1,PNMA1,SIK3,RAP1GAP2,FERMT2,MEX3B,UBC,HSPA1B,IRS1,CUL2,SNX24,NCOR1,ZAK |
| 5.239e-04 | -7.55 | COLDREN_GEFITINIB_RESISTANCE_UP | MSigDB lists | COLDREN_GEFITINIB_RESISTANCE_UP | 77 | 21 | 17758 | 2279 |
C18orf21,ITPRIP,C10orf2,NOL8,C16orf45,BMS1,C10orf76,IKBIP,PTPRG,USP36,TAMM41,SLC7A1,SLC39A14,SACS,ZEB1,TBL1X,PDCD11,TMEM158,CSGALNACT2,TIMM50,RABEPK |
| 5.257e-04 | -7.55 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | 481 | 87 | 17758 | 2279 |
ZNF706,NDUFA5,CYLD,ID1,MMRN2,NF1,ARID2,LPCAT2,PBX1,PRR4,SSBP2,PTPRG,FAM13A,UBR5,GIT2,GABPB2,AHCYL2,TMEM150C,ANKRD13A,ZFHX3,CBR4,WAC,GSTA4,SLC25A23,MAML3,FMNL3,GPM6A,EIF4E3,AKAP12,MARCKSL1,AKAP13,TCTN1,SAP30BP,ST3GAL5,BTBD11,GNAI1,TOM1L2,SH3RF1,BDH2,FKBP5,MDN1,MAGI1,MEF2C,EPM2AIP1,EGR1,FOXO1,RFX1,STXBP6,DYM,TATDN3,MED13L,SMG7,C14orf159,ATF7IP,PLA2G12A,FOXP1,GIGYF2,MAN1A1,MTUS1,MCAM,NEBL,KIAA1671,ABCA5,NISCH,SAMD13,ZCCHC7,CAV2,PKNOX1,PDE4A,AP4S1,ERICH1,PHACTR2,ST6GALNAC3,RERE,ATP9B,FBXO21,NSD1,KIDINS220,SERF2,NME7,ACOX1,HERC1,SDCCAG8,TBX3,PTPN4,PDLIM5,PDSS2 |
| 5.267e-04 | -7.55 | nuclear chromosome part | cellular component | GO:0044454 | 446 | 81 | 17570 | 2233 |
TCF12,ATRX,PLRG1,NAT10,CSNK2A1,SMARCA4,SIRT2,TNKS1BP1,RING1,KDM1A,SMARCB1,TERF2IP,SLX4,BCAS2,KDM2A,ACD,UCHL5,RNF2,POLE3,MSH4,CTC1,PRPF19,HMBOX1,BRD4,SIRT6,HIST1H2BL,MCM2,ENC1,CHAF1A,SMAD3,TRRAP,SMARCC1,TP53BP1,KLF4,E2F4,H2AFX,PUS1,NFRKB,EME1,CCNB1IP1,EP400,MCM6,MCM10,TCF3,SIRT7,DPF2,H2AFJ,MLH1,HIST2H2AB,POGZ,CDC73,SFR1,POLR3D,MCM5,MBD2,BUD31,TIMELESS,NRIP1,TERF2,TOP1,GATAD2B,TRNP1,SMARCAD1,POLA1,SMARCD3,APTX,HIST1H4J,ARID1A,PLCB1,FOXC1,TCF7L2,ZRANB3,POLR3G,RPA1,POLE2,EHMT2,ORC5,PURB,NCOR1,KDM4C,IPO4 |
| 5.268e-04 | -7.55 | bone-tibia-other-chondroblastoma | COSMIC cancer mutations | bone-tibia-other-chondroblastoma | 104 | 26 | 17775 | 2278 |
DTNB,GPM6A,CRADD,ADAMTSL3,CNTNAP3,TRIO,MED27,SLC25A12,CLSTN2,KSR2,ST6GALNAC3,RNF43,PALLD,PLCB1,NAALADL2,SMPDL3B,RAB10,PHC2,ZNF804A,LRP1B,KDM2A,NUP133,DDX31,NMD3,SMG1,COG5 |
| 5.294e-04 | -7.54 | positive regulation of fibroblast proliferation | biological process | GO:0048146 | 56 | 17 | 16441 | 2138 |
NRAS,FN1,SIRT6,CDK4,DDR2,LIG4,GAS6,FOSL2,KMT2C,RNASEH2B,MYC,FNTB,ANXA2,UTS2,BMI1,CDK6,CTC1 |
| 5.367e-04 | -7.53 | IRITANI_MAD1_TARGETS_DN | MSigDB lists | IRITANI_MAD1_TARGETS_DN | 47 | 15 | 17758 | 2279 |
DCTPP1,CAD,SRM,RARS,MYBBP1A,MCM6,APEX1,WDR74,SLC16A1,DTD1,GPAM,CPSF3,FBL,PPA1,LONP1 |
| 5.376e-04 | -7.53 | HNRNPL (heterogeneous nuclear ribonucleoprotein L) | protein interactions | 3191 | 105 | 28 | 16036 | 2270 |
SNU13,CUL7,APEX1,FN1,NARS,SMARCAD1,ACTR3,HSPA5,LGALS1,CSNK2A1,MBNL1,HNRNPA3,UBC,ISG15,NEDD4,RPA1,DYNC1H1,SYNCRIP,HNRNPR,LSM14A,COPS5,MPV17,RNF2,FUS,SRRM2,HNRNPM,TOP1,LPP |
| 5.395e-04 | -7.52 | XU_GH1_AUTOCRINE_TARGETS_DN | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_DN | 132 | 31 | 17758 | 2279 |
EFNB2,DBN1,GDAP1,KDM5B,SLC38A1,SLK,SETD2,ARID5B,CUX1,PREX1,NLN,RSL1D1,C10orf76,PPIP5K2,FOXP1,HSPA1A,NAALADL2,HSPA1B,DYRK1B,PXDN,DNAJC1,PMEPA1,NBEA,SEMA3C,RPS6KB1,CD44,TPM1,NR2F2,LAMA5,PTPN14,PTPRK |
| 5.402e-04 | -7.52 | RBM19 (RNA binding motif protein 19) | protein interactions | 9904 | 19 | 9 | 16036 | 2270 |
NIFK,TSR1,NOL10,DHX37,UTP15,PTPN12,FBL,FTSJ3,ZC3H3 |
| 5.423e-04 | -7.52 | EBNA1BP2 (EBNA1 binding protein 2) | protein interactions | 10969 | 90 | 25 | 16036 | 2270 |
ADARB1,NIFK,CUL7,DDX24,DDX18,GNL3,SIRT7,NOL6,BRCA1,ZNF346,NOP58,PUM3,NOP56,PES1,POP1,DDX56,ZNF622,MPHOSPH10,ADNP,COPS5,CEBPZ,NOC3L,POLR1C,FBL,FTSJ3 |
| 5.447e-04 | -7.52 | RODRIGUES_THYROID_CARCINOMA_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_DN | 72 | 20 | 17758 | 2279 |
PHLDB2,PGPEP1,FN1,TRA2A,KCNMA1,ZNF512B,ATXN1,IGF2BP2,RSF1,PLCB1,DCBLD2,NAMPT,S100A10,PMEPA1,HIPK2,ZNF160,CD44,ZMYM2,CDK6,PTPRK |
| 5.474e-04 | -7.51 | V$MYOD_Q6_01 | MSigDB lists | V$MYOD_Q6_01 | 239 | 49 | 17758 | 2279 |
GNB3,PRPF38B,CYLD,ESCO1,PAFAH1B1,CACNA1H,CLSTN2,KLHL18,WNT2B,DST,FMNL1,JAZF1,VGF,NDRG4,CTR9,IGF2BP1,ZNF710,YARS,SERBP1,HN1,SPTAN1,HMBOX1,BDNF,USP49,PRDM16,ARRDC3,JMJD1C,AKAP12,SEMA3F,ARHGEF12,KCNH2,ARL5B,UBE2E1,SPOP,UBTF,VDR,SMAD3,SPAG9,KIAA0355,ARL4A,CSRNP1,INTS9,CCDC85B,MBD6,RUNX1,SORCS2,DOCK6,ZMAT3,ATXN7L2 |
| 5.474e-04 | -7.51 | V$ELK1_02 | MSigDB lists | V$ELK1_02 | 239 | 49 | 17758 | 2279 |
INSIG2,PAPD4,NF1,WDR74,ITFG1,FANCD2,MAPK8IP3,PPHLN1,AKT1S1,AP1B1,TIGD1,C1orf50,SLC30A7,GART,SHC1,UBR1,SEC24C,AP1M1,VPS52,ARHGAP1,CPSF3,OGG1,CPSF3L,PRKACB,LYPLA2,CSGALNACT2,TTPAL,RFC4,TIMM8B,NRAS,TSTA3,SIRT6,MARS,KRTCAP2,SUPT5H,SON,ARL5B,NUP214,STOML2,PALB2,SRBD1,PTRH2,PURB,GGT7,ZBTB11,AP2S1,IPO4,LRRC41,STK4 |
| 5.475e-04 | -7.51 | CDK11A (cyclin-dependent kinase 11A) | protein interactions | 728642 | 52 | 17 | 16036 | 2270 |
SKIV2L,DPF2,ZFP14,CSNK2A1,CCNL2,NOP58,SAP30BP,PELP1,SMAD3,GADD45A,HKR1,CTR9,FKBP5,ZNF460,NOLC1,C18orf25,CDC37 |
| 5.492e-04 | -7.51 | MORF_FANCG | MSigDB lists | MORF_FANCG | 161 | 36 | 17758 | 2279 |
FAM189B,ATRX,PRKCSH,PAFAH1B1,SLC2A1,KLHL18,CSNK2A1,TTI1,PARN,PITPNM1,PPIL2,RPS6KB2,KDM3B,CHD9,SIK3,GTF2H3,MSX1,TSTA3,LSM12,SFSWAP,BMS1,EIF5B,POLR2A,MFN2,RERE,HTR7,PWP1,SEC31A,TAF2,RANBP2,SLC30A3,RBBP8,CHD3,SLC25A11,NFRKB,XPO6 |
| 5.530e-04 | -7.50 | YOSHIMURA_MAPK8_TARGETS_DN | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_DN | 352 | 67 | 17758 | 2279 |
ZNF292,MYCBP2,ACTG1,NF1,ATP6V1A,PTPRA,PLOD1,SMARCA4,FDX1,JAG1,S100A10,NVL,ANKRD24,ZEB1,CHD2,SERPINH1,LYST,TMPO,PDK1,PTPRM,NFIA,ODC1,SERP1,ST3GAL5,FGFR1,MLLT10,LSS,AHNAK,GATA6,INSIG1,DPP4,RPS6KB1,MAGI1,NOLC1,PPIL3,LAMA5,FN1,JUP,SLK,TCF3,PDE4B,SSR4,BHLHE40,SUB1,MYC,PRICKLE2,PTGS1,HMGCR,BDNF,PSAT1,WDR61,GPHN,PPAT,SCFD2,PSMA1,CYB5B,MFN2,CAT,EHMT2,GADD45A,FDPS,SLC16A1,PURB,GPAM,PSAP,NR2F2,RABEP1 |
| 5.543e-04 | -7.50 | ALFANO_MYC_TARGETS | MSigDB lists | ALFANO_MYC_TARGETS | 233 | 48 | 17758 | 2279 |
ABCA3,TRIP6,CELSR3,CLK1,GPR143,RSL1D1,GAS6,TGFB2,NOP56,FARSA,ANXA7,SURF2,S100A10,DNAJB6,CACNB2,MYC,ZEB1,VCL,MGLL,CAMKK2,PXN,PPAT,MTIF2,PCCA,ABCF2,PTPN12,PSMG1,AKAP12,MCL1,KCNH2,UBE2K,DLST,TCF7L2,HERPUD1,ANXA1,PYCR1,PES1,TRAP1,SYNGR2,LARGE,SVIL,SLC16A1,MDN1,BMP4,PDCD11,BLMH,DHCR7,RBP1 |
| 5.584e-04 | -7.49 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 | 167 | 37 | 17758 | 2279 |
NDUFA5,CHMP2A,C9orf78,NDUFB5,LAGE3,DPM3,PDCD5,LYRM2,REEP5,UBL5,HDDC2,ETFB,RPP30,PEX7,PSMG4,S100A10,RELB,POLE3,ELOF1,TIMM8B,NAA38,IFNGR2,ANAPC13,PSAT1,LGALS1,SUMO3,CYB5B,C19orf70,FKBP3,ECH1,ANXA1,ATP5D,CAT,PQBP1,GPN1,NCBP2,ANXA2 |
| 5.604e-04 | -7.49 | MITOCHONDRIAL_MEMBRANE_PART | MSigDB lists | MITOCHONDRIAL_MEMBRANE_PART | 52 | 16 | 17758 | 2279 |
TIMM8B,BCS1L,OPA1,RHOT2,TIMM10,NDUFS7,MFN2,ATP5D,TAMM41,NDUFV1,ATP5G2,TIMM17A,SURF1,FIS1,NDUFA6,TIMM50 |
| 5.606e-04 | -7.49 | HUANG_GATA2_TARGETS_DN | MSigDB lists | HUANG_GATA2_TARGETS_DN | 67 | 19 | 17758 | 2279 |
EGR1,SLC2A1,TMEM109,PBX1,JMJD6,MTHFD1L,CHAC1,ST3GAL6,TMEM132A,ESAM,ASNS,MTHFD2,NSF,FDPS,HK2,SHMT2,ETF1,CLU,IPO11 |
| 5.642e-04 | -7.48 | ACAGGGT,MIR-10A,MIR-10B | MSigDB lists | ACAGGGT,MIR-10A,MIR-10B | 121 | 29 | 17758 | 2279 |
SOBP,NCOR2,BDNF,RB1CC1,PAFAH1B1,ELOVL6,TMEM183A,ARRDC3,WDR26,SON,USP46,IGSF1,BTBD11,ZNF608,BAZ2B,GATA6,HAS3,SLC38A2,HOXA3,PURB,GTF2H1,COPS7B,PRRT3,ARHGAP12,CNOT6,NFASC,ERI3,FNBP1L,SLC25A1 |
| 5.700e-04 | -7.47 | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | MSigDB lists | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | 62 | 18 | 17758 | 2279 |
TTN,EPM2AIP1,CRADD,TRIP6,XPC,SLC2A1,PCSK7,SEMA6A,SFI1,PHC2,SOCS1,TP53BP1,E2F4,VCAN,CDK9,PDE9A,N4BP2L2,CASP10 |
| 5.736e-04 | -7.46 | S15_NS1_RNA-bd | interpro domains | IPR009068 | 7 | 5 | 18293 | 2341 |
MARS,EPRS,GARS,HARS,WARS |
| 5.736e-04 | -7.46 | KIM_WT1_TARGETS_UP | MSigDB lists | KIM_WT1_TARGETS_UP | 209 | 44 | 17758 | 2279 |
HMGA2,SPRED2,EGR1,ACTG1,SPATA2L,TRIO,GTF2IRD1,ZFP36L1,BHLHE40,FOSL2,PHLDA2,MAP2K3,PCDH7,SH2B3,CHD7,PDE10A,MYC,RELB,ZEB1,SYNJ2,CD44,VCL,KDM6B,FLNC,DNMBP,IFNGR2,BAZ2A,ARID5B,AKAP12,FERMT2,MAPK1IP1L,PITPNB,ENC1,FOXC1,ST3GAL5,SMAD3,GLS,BAZ1A,SLC7A1,TBX3,TRAF3,ARC,PDLIM5,MTMR1 |
| 5.743e-04 | -7.46 | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | MSigDB lists | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | 812 | 136 | 17758 | 2279 |
PIGM,TFIP11,AARS2,TOM1L1,SRSF2,SREBF2,S100A10,ATG3,ANAPC10,PAK1IP1,PCOLCE2,PPM1K,NRAS,GMFB,PSMG1,TCTN1,ODC1,SLC50A1,LSG1,HPRT1,DDAH2,SUPT4H1,EIF4ENIF1,MPV17,BMI1,ZMAT3,EFNB2,EPM2AIP1,DROSHA,ZHX3,SEC24D,STXBP6,PDCD7,PDCD5,YARS2,MCM5,TIMELESS,CTR9,CCDC167,GMDS,PPA1,TERF2,PEA15,VOPP1,RANBP6,LAMC1,WDR61,PPAT,ELOVL6,RDH10,PTPN12,MAPK1IP1L,EIF2A,C19orf70,TBC1D2,EPRS,FAT1,BIVM,SURF1,GPN1,ARHGAP12,KIAA0196,SH3PXD2A,C12orf45,NR2C2AP,SNX27,NDUFAF2,TMEM183A,LAGE3,NDUFB5,ZMAT2,HSPA1A,DHX35,SLC39A1,NDUFB3,RIOK2,IDI1,LYPLAL1,NUP133,PPID,FGGY,UCHL5,MRPS27,ETF1,SERPINH1,TSPAN14,GNG5,TMEM14C,LSM10,RFC4,COL5A2,TUBA1A,EIF3J,SATB2,TBC1D16,SERP1,SMARCC1,HNRNPR,NSMCE2,POLR3E,TSSC1,H2AFX,ACP1,FKBP5,USP11,YEATS2,MIF4GD,SCAMP3,VPS45,FARS2,MAP1S,MLH1,TRIM22,BZW2,RSRC1,RMI1,DCTPP1,SELT,HARS2,SPTAN1,KDM5B,APEX1,ANKMY2,MARS,C8orf33,FOXC1,HSPA1B,MRPL36,RPA1,CUL2,SET,NCBP2,TAF12,TATDN1,IGBP1,IPO4 |
| 5.744e-04 | -7.46 | GSE25087_FETAL_VS_ADULT_TCONV_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_UP | 185 | 40 | 17758 | 2279 |
SUCLG1,LRRC28,LPCAT2,TCF3,ADAMTS6,APRT,CHAC1,PIP4K2A,NDUFB3,CHD7,SH2B3,COMMD9,ZNF827,CCDC50,INTS7,ATIC,METTL8,SSBP1,TRIP13,C12orf4,MBTPS2,PTPRK,FADS1,TIMM8B,ATF4,ADSL,PHACTR2,COTL1,ZSCAN2,SOX4,TARS,TMCO1,RBBP8,IKZF4,FSCN1,SLC16A1,PRPF4,EME1,ANXA2,ECHDC1 |
| 5.744e-04 | -7.46 | PIGF_UP.V1_UP | MSigDB lists | PIGF_UP.V1_UP | 185 | 40 | 17758 | 2279 |
PHF3,SPRYD7,NECAP1,OPA1,AHCYL2,RAP1A,SACS,BCAS2,ARMC6,ZNF354A,PPID,TRMU,UPF2,AGL,PRKACB,ANGPT2,MBTPS2,SCAF11,SLC38A6,ANAPC13,PPAT,SKIV2L2,GMFB,CRYBG3,RDH11,PEX1,ASCC3,IREB2,BAZ2B,HIF1A,VCAN,ARL4A,CEBPZ,ITGA2,SLC4A7,ADAM9,DMTF1,MAP2K4,N4BP2L2,HS2ST1 |
| 5.764e-04 | -7.46 | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | 191 | 41 | 17758 | 2279 |
VIPR1,SEPHS2,AK2,FEM1C,EGR1,PRKCSH,KHDRBS1,SIRT7,SMAD7,SIRT2,OPA1,RSRC1,MGA,NDUFS7,NOP56,EXOC1,MPHOSPH10,THADA,KDELC1,CLDND1,EXOSC4,ITGAX,TRIM14,MBTPS2,FAM120B,DDX28,TRIM13,AEBP2,KDM5B,PACRGL,TARS,PHF6,MRPL36,DDX3X,ALKBH3,ARID3B,SURF1,ADAM9,ALKBH1,ZFP90,ZBTB24 |
| 5.764e-04 | -7.46 | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN | 191 | 41 | 17758 | 2279 |
VMA21,MCM10,ACTR3,LAMTOR3,C1orf52,XPO7,OPA1,POGZ,AHCYL2,RPP30,TAF3,MCM5,SSBP1,PRPS1,HSD17B12,MBTPS2,HMGCR,FDFT1,SAP30,GARS,HARS,NARS,PSPC1,USP42,LDHA,RSBN1,DCUN1D5,MCM2,FLVCR1,YTHDF2,SLC7A1,CDC16,SMARCC1,TP53BP1,COPS5,ZNF236,SET,SQLE,PEX13,PDLIM5,SETD6 |
| 5.764e-04 | -7.46 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_UP | 191 | 41 | 17758 | 2279 |
TCF12,AK2,PCNT,DROSHA,PIGH,FAN1,NFX1,SMARCA4,LYRM2,STAM,MRPS30,CFDP1,JOSD1,HARS2,RAN,FBL,ZNF460,PRPF19,CDC37,DSC3,ZCCHC14,RREB1,PDE4A,RNMT,TYW1,RNH1,RAP1GDS1,PCNXL2,EIF5B,TARS,CLNS1A,USP36,ANXA1,PWP1,FBXO21,COPS5,POLR3E,GPN1,FNTB,PUS1,FAM118A |
| 5.768e-04 | -7.46 | HALLMARK_G2M_CHECKPOINT | MSigDB lists | HALLMARK_G2M_CHECKPOINT | 197 | 42 | 17758 | 2279 |
MCM6,CUL4A,ATRX,PAFAH1B1,DBF4,RPS6KA5,ABL1,SRSF2,MCM5,MYC,PDS5B,PRMT5,CASP8AP2,HN1,TMPO,TOP1,SAP30,STAG1,PRIM2,SLC38A1,TLE3,CDK4,FOXN3,KIF15,MCM2,DKC1,ODC1,CHAF1A,SMAD3,EXO1,SLC7A1,BRCA2,SYNCRIP,SMARCC1,HIF1A,CCNT1,E2F4,ORC5,H2AFX,SQLE,NOLC1,ZAK |
| 5.804e-04 | -7.45 | ACATTCC,MIR-1,MIR-206 | MSigDB lists | ACATTCC,MIR-1,MIR-206 | 283 | 56 | 17758 | 2279 |
SLC37A3,EFNB2,FN1,CELSR3,UBN1,ATP6V1A,ARID2,PAFAH1B1,SMARCA4,ZFP36L1,MON2,IP6K2,PTPRG,FOXP1,UBR5,SMARCB1,PHC2,ZNF827,STC2,JOSD1,SYNJ2,ANP32B,MET,CDK6,AKAP11,ELOF1,HMGCR,BDNF,WDR61,TSPYL4,POLA1,ARRDC3,PREX1,DLG4,LRRC8A,AKAP12,RSBN1,SNAP25,CYB5B,PHF6,BSN,NAP1L5,BICD1,CDK9,G6PD,ZNF236,CEBPZ,RNF138,HIC2,ANXA2,BPNT1,NRP1,PDLIM5,MIPOL1,ZMAT3,TMCC1 |
| 5.811e-04 | -7.45 | spinal_cord | COSMIC cancer mutations | spinal_cord | 150 | 34 | 17775 | 2278 |
BRAF,NF1,BCOR,MLH1,SMARCB1,ABL1,DST,ANKRD13A,MCM5,CCDC40,PRICKLE2,MET,KIAA1549,C12orf4,CARM1,CTC1,ARNTL2,FMNL3,NRAS,ADAMTSL3,PLEKHM3,BRCA1,MEN1,KMT2C,FGFR1,KIF16B,EXO1,TRIB3,BRCA2,SUFU,ATM,GPN1,RUNX1,MAP2K4 |
| 5.811e-04 | -7.45 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 99 | 25 | 17758 | 2279 |
SLC3A2,GARS,ATF4,PDK1,GNG7,LDHA,MARS,PRDM1,CAV1,SPATS2,BMP6,PABPC4,ATP5D,NAMPT,SUB1,ELL,EIF2S2,MYC,SLC38A2,PAM,ACP1,HMBS,YARS,BMI1,DDIT3 |
| 5.811e-04 | -7.45 | HELLER_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_DN | 99 | 25 | 17758 | 2279 |
IFRD1,SLC3A2,ATF4,PSAT1,CLK1,SEC24D,MARS,CHAC1,PHGDH,HSPA1A,HSPA1B,WARS,DDIT4,TIMM44,TRIB3,ASNS,SLC7A11,LRP2BP,MYC,PPFIBP1,CTAGE5,SHMT2,SERPINH1,MMP16,DDIT3 |
| 5.826e-04 | -7.45 | SWI/SNF superfamily-type complex | cellular component | GO:0070603 | 73 | 20 | 17570 | 2233 |
GATAD2B,DPF3,EP400,ARID2,ATRX,DPF2,CSNK2A1,SMARCA4,SMARCD3,RSF1,ARID1A,CHD5,ARID1B,SMARCB1,BAZ1A,TRRAP,SMARCC1,CHD3,UCHL5,NFRKB |
| 5.828e-04 | -7.45 | NUYTTEN_EZH2_TARGETS_DN | MSigDB lists | NUYTTEN_EZH2_TARGETS_DN | 957 | 157 | 17758 | 2279 |
PIGM,BCAS4,FANCD2,SLC29A1,GYG1,NLE1,GIT2,GABPB2,PCYOX1L,SRPRB,THADA,DHX33,SLC39A7,ZMYM2,TMPO,TRIM13,ZNF680,PPARG,GPCPD1,TSN,CUX1,KIF15,WDHD1,PSMG1,EFHC1,BRCA1,MCM2,FLVCR1,CHAF1A,SLC7A1,HPRT1,BRCA2,RAD18,TRMT5,DNAH2,LARS2,PHGDH,LYRM2,TIMM10,CMTM3,ETFB,RNF141,SLC7A11,CACNB2,BANF1,ZNF326,GTF2H1,TIMELESS,SLC16A9,NOC3L,GEMIN4,ALDH18A1,RABEPK,MYB,NIPSNAP1,USE1,FADS1,LRRC20,EXOSC2,TRA2A,ZBED4,HAUS6,TBXAS1,IMPDH2,CYB5B,TRIM37,TCF7L2,TASP1,SNAP23,LEMD3,PURB,ZNF430,UMPS,HMBS,TBL1X,WDR33,PDSS2,NR2C2AP,CPT1C,VMA21,RAB11FIP4,RIBC2,LAGE3,MYH9,FAM122B,NUP43,SSBP2,POP5,RPAIN,CAD,JAG1,IDI1,ACD,PYCRL,NT5C,HIBCH,CPSF3,NARS2,RFC4,EIF3J,ARHGEF10,METTL15,GNL1,GALK2,SETD7,DKC1,USP36,RAD54B,EXO1,NSMCE2,H2AFX,HOXA3,SLC4A7,SLC25A11,FKBP5,PRRT3,HEATR1,MUTYH,FGFBP3,TMEM141,AUH,MCM10,MIF4GD,CMTM8,H2AFJ,ARFIP2,NOL3,DNAJC22,OPA1,RPS6KA5,FAM8A1,RMI1,GART,NEBL,TRIAP1,TMEM99,LARP4B,FBL,PCK2,PNMA1,SNAPC5,HNRNPM,DDHD1,SLC40A1,CRIM1,FOXN3,PTK2,FBXO21,SRBD1,ORC5,VPS37B,SET,RNF138,GPAM,ZAK,NUDT22,GPATCH4 |
| 5.871e-04 | -7.44 | MODULE_21 | MSigDB lists | MODULE_21 | 10 | 6 | 17758 | 2279 |
UMPS,APRT,HPRT1,IMPDH2,GART,ADK |
| 5.871e-04 | -7.44 | RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | RESPONSE_TO_IONIZING_RADIATION | 10 | 6 | 17758 | 2279 |
LIG4,ATM,IKBIP,BRCC3,XRCC4,XRRA1 |
| 5.959e-04 | -7.43 | TRANSCRIPTION_REPRESSOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_REPRESSOR_ACTIVITY | 150 | 34 | 17758 | 2279 |
NCOR2,ID1,RBFOX2,KHDRBS1,PLRG1,ID2,BCOR,RSF1,TRIM22,RING1,JAZF1,RELB,ZEB1,ZNF85,NRIP1,CASP8AP2,SAP30,APEX1,KDM5B,FOXN3,ARID5B,ATXN1,BATF3,SKIL,NSD1,TRIB3,SUFU,IKZF4,KLF4,HIPK2,TBX3,NCOR1,NR2F2,DDIT3 |
| 5.966e-04 | -7.42 | DNA-templated transcription, initiation | biological process | GO:0006352 | 286 | 57 | 16441 | 2138 |
NCOR2,TAF1,PRKAB2,POLR1A,SMAD7,LAMTOR3,RSF1,SKI,DDIT4,SNW1,RRN3,PTRF,TAF3,MYC,GTF2H1,MED24,RNF111,POLR1B,ZNRD1,POLR1E,SNAPC5,MAML3,GTF2H3,SESN2,PPARG,NR6A1,TEAD1,MED27,MED16,MEN1,UBC,NR2F1,POLR2A,POLR3G,TAF9B,VDR,TAF2,SKIL,GLS,UBTF,SMAD3,GTF2A1,CCNT1,CDK9,G6PD,E2F4,MED15,TAF4,RRAGA,TBPL1,CRCP,RBPJ,NCOR1,MED20,TAF12,POLR1C,NR2C2AP |
| 5.971e-04 | -7.42 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 1942 | 299 | 16441 | 2138 |
PTP4A1,PRDX6,PRKAB2,NT5C3A,PRKCA,ABHD6,SYNJ1,LPIN1,NEK6,ATP5G2,ME1,FNIP2,FXN,CDK6,PPM1K,NRAS,UPP1,PTPRM,EYA3,STOML2,TRRAP,SSU72,CCNT1,RIOK1,PTPN14,MEF2C,SLK,TRIO,AK6,PIK3R4,DPM3,PLA2G12A,TGFBR2,NDUFS7,PRKCE,PI4KB,ENTPD5,MYC,ATIC,PIGG,MAP3K12,LPCAT1,PRPS1,PPA1,FDFT1,HMGCR,FADS1,PEA15,SIK3,GTF2H3,BDNF,SYNGAP1,RB1CC1,IDH3G,PTPN12,IMPDH2,PLCB1,IRS1,CAT,NME7,CDK9,SURF1,RIOK3,UMPS,BPNT1,MAP2K4,MAP2K5,BIRC6,PAFAH1B1,ATP6V1A,PDK4,NDUFB5,OLA1,DDR2,PTPRG,LCLAT1,HSPA1A,PDE3A,NDUFB3,FLAD1,PRKD3,SHC1,LPIN2,NT5C,CMPK1,PXK,MTHFD2L,MGLL,CDK12,LYST,GARS,BRD4,PDK1,PI4KAP2,DLG4,ATP6V0A1,GALK2,KCNH3,NUDT15,STK10,ERC1,FGFR1,PDE8B,SNCA,TAMM41,CAMK2D,DCXR,HIPK2,G6PD,PEMT,ACP1,RPS6KB1,HMGA2,SSH2,SERINC5,BRAF,GAS6,IP6K2,IKBKAP,TGFB2,RNASEH2B,RPS6KA5,INPP1,RSRC1,PSMF1,DCTPP1,ABL1,NPRL2,MAP3K14,NT5M,SPTAN1,CLK2,PFKFB4,FGF9,PXN,AGPAT4,LDHA,ADSL,TBRG4,PTK2,APTX,PPIP5K2,PDE3B,UBC,OXSR1,TRIB3,PLPPR2,COQ9,SRD5A3,ATM,PTPN4,NDUFS5,GPAM,BMP4,PGAM5,ADK,MTMR1,STK4,PIGM,MVK,NF1,PTPRA,TRPM6,CSNK2A1,STK33,COX10,MAP2K3,ABL2,AMPD3,PHKA1,PPCDC,MYH3,NDUFA6,OGG1,PRKACB,TIMM50,PTPRK,SRPK2,TNK2,ITPA,CDK4,GPCPD1,COL4A3BP,GMFB,KSR2,PITPNB,CAV1,KCNH2,SGK2,DLST,DYRK1B,HPRT1,GATA6,PPP3CC,USP15,SEPHS2,XYLB,TTN,PIGN,AK2,CLK1,TAF1,GPAT3,SMAD7,LAMTOR3,MAPK8IP3,NAMPT,PDE10A,GTF2H1,SYNJ2,PNPLA3,ALDH18A1,N4BP2,MTHFD1,NT5E,CAMKK2,PDE4A,PPAT,OBSCN,PSMA1,MEX3B,EIF2A,VAC14,PGD,SPAG9,IRAK2,FDPS,TBPL1,HK2,CASS4,PTP4A2,BRSK2,TBCK,PDE9A,NDUFA5,SUCLG1,LPCAT2,NTSR1,PIGH,PPP2R2A,RIPK1,LPCAT3,PUDP,PIBF1,RIOK2,CAD,IDI1,GRIN2C,FGGY,RPS6KL1,IKBKB,FHIT,ADCK4,MET,MCEE,AKAP13,TPK1,ATP5D,ABHD3,DUSP19,MUTYH,SMG1,TNIK,BCKDK,MINK1,SULT1C2,SH2D3A,MAP3K13,CAMK1,PDE4B,TKFC,CHCHD10,APRT,CSNK1A1,PIP4K2A,PTPN2,PRKCH,GART,NDUFV1,CPNE7,RPS6KB2,TOP1,GPHN,FGF2,SMARCAD1,TEX14,SULT4A1,MEN1,PDE2A,PEAK1,NAPEPLD,PIK3CB,SMPDL3B,HSPA1B,ALG5,SERINC1,EIF2S1,RPS6KC1,ZAK |
| 6.016e-04 | -7.42 | KEGG_ONE_CARBON_POOL_BY_FOLATE | MSigDB lists | KEGG_ONE_CARBON_POOL_BY_FOLATE | 17 | 8 | 17758 | 2279 |
GART,MTHFD2,ATIC,SHMT2,MTHFD1L,MTHFD2L,MTR,MTHFD1 |
| 6.093e-04 | -7.40 | Validated targets of C-MYC transcriptional activation | Pathway Interaction DB | myc_activpathway | 81 | 23 | 2227 | 319 |
LIN28B,DDX18,NDUFAF2,CDK4,SLC2A1,LDHA,MINA,ID2,ODC1,UBTF,CAD,SMAD3,POLR3D,IREB2,NME1-NME2,TRRAP,PMAIP1,MYC,EIF2S1,TAF12,GPAM,PEG10,BMI1 |
| 6.094e-04 | -7.40 | CTPS1 (CTP synthase 1) | protein interactions | 1503 | 57 | 18 | 16036 | 2270 |
WDR36,SNU13,GINS3,SKIV2L2,UBXN1,TSN,IMPDH2,RBM28,CLNS1A,DCTPP1,MYC,COPS5,CUL2,PRMT5,POLR1C,VCL,NMD3,RTFDC1 |
| 6.123e-04 | -7.40 | V$YY1_01 | MSigDB lists | V$YY1_01 | 234 | 48 | 17758 | 2279 |
SSH2,ASH1L,ID1,ANKRD17,PAFAH1B1,PRKAB2,PPP2R2A,RNF43,IP6K2,GBF1,PLXNB1,PEX7,UBE3A,SRSF2,ATP5G2,FSIP2,CACNB2,MED24,SELT,CHD2,CEP135,SRRM2,ZNF646,SOBP,NRAS,STAG1,AKAP8L,KIRREL2,ZNF654,TLE3,SETD2,VSNL1,NLN,SNAP25,PHF6,NCDN,CXADR,DDX3X,SYNCRIP,GTF2A1,ADNP,LUC7L3,HIC2,TRAF3,TPM1,ADK,ZAK,KIF1B |
| 6.179e-04 | -7.39 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | 347 | 66 | 17758 | 2279 |
CYP24A1,GGT1,ZNF516,SLC5A5,SLC48A1,SSBP2,FAM13A,EEA1,RING1,CAD,FARSA,NCKIPSD,UBAP2L,SOCS6,MAD1L1,ZC3H3,TRIP13,MAML3,SAP30,METTL1,ATP6V0A1,MARCKSL1,MCM2,NUP214,RAD54B,RBBP8,KLF4,H2AFX,ZNF507,COMMD10,FN1,STXBP6,VARS,RNASEH2B,SLC1A1,BZW2,NEDD4,FKBP1A,TSPAN2,MCAM,STC2,EXOSC4,ERI3,PRMT5,SERBP1,CPSF3L,PRIM2,IFNGR2,TSTA3,EPS15L1,ARHGAP32,IMPDH2,PTK2,KLF6,TCF7L2,NCDN,DKK1,IRS1,INF2,BAZ2B,ZDHHC11,RPL28,ADK,NAPA,C18orf25,IPO4 |
| 6.185e-04 | -7.39 | POLR3F (polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa) | protein interactions | 10621 | 35 | 13 | 16036 | 2270 |
POLR3D,SUV39H2,STC2,POLR3E,CRCP,SMARCA4,RSL1D1,POLR3B,POLR1C,RBM28,NOP58,POLR3A,POLR3G |
| 6.191e-04 | -7.39 | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | 265 | 53 | 17758 | 2279 |
IMMP2L,MYCBP2,EP400,BIRC6,LUZP1,UBN1,NPAS2,B4GALT5,OSBPL9,SLC2A1,CSNK2A1,RIPK1,IGF2BP2,SEC16A,BIRC2,GABPB2,KDM1A,RSPRY1,PRKD3,SACS,JAG1,MYC,GTF2H1,NOC3L,CMPK1,TSPAN14,ZMYM2,SRRM2,C15orf41,SAMD4A,PRKACB,SERBP1,PTPRK,TMPO,TOP1,SRPK2,SSFA2,PRIM2,MTIF2,ELOVL6,JMJD1C,RAP1B,ADSL,EIF2A,DKC1,SON,MAT2A,PHF6,RAD54B,PEX1,KDM4B,LSM14A,VCAN |
| 6.195e-04 | -7.39 | DCAF13 (DDB1 and CUL4 associated factor 13) | protein interactions | 25879 | 23 | 10 | 16036 | 2270 |
WDR36,UTP14A,DDX18,SIRT7,FBL,POLR1C,NOP58,PUM3,WARS,NOP56 |
| 6.199e-04 | -7.39 | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | MSigDB lists | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | 25 | 10 | 17758 | 2279 |
PXN,FN1,ANXA5,CAV1,MET,NRP1,TGFB2,CD44,VCL,TGFBR2 |
| 6.209e-04 | -7.38 | HIST3H3 (histone cluster 3, H3) | protein interactions | 8290 | 230 | 51 | 16036 | 2270 |
ZNF516,TAF1,DPF2,PRKCA,RPS6KA5,CHD5,POGZ,MGA,KDM1A,RING1,PHC2,TADA3,KDM2A,APLF,TAF3,GLYR1,HIRIP3,RNF2,KMT2A,SAP30,KDM3B,PRAME,RREB1,KDM5A,EHMT1,SETD2,HDAC8,SUPT20H,SETD7,MCM2,MEN1,CHAF1A,DOT1L,TAF9B,TAF2,NSD1,KPNA1,EHMT2,GADD45A,HNRNPR,ADNP,SET,ORC5,TAF4,RAD51B,TAF12,BMI1,SMYD3,IPO4,KAT6A,EMSY |
| 6.292e-04 | -7.37 | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP | 168 | 37 | 17758 | 2279 |
SERINC5,FAM208B,PHF3,CYLD,BRAF,ZHX3,PDE4B,NECAP1,C1orf52,SAFB2,GIGYF2,NAMPT,ANKRD11,CHD2,CMPK1,SF3A1,MSI2,PTBP2,DDX24,SETD1B,USP42,JMJD1C,EIF4A2,FERMT2,RANGAP1,MEF2D,MARCH6,USP36,RANBP2,L3MBTL3,HIF1A,ZNF236,ARNTL,POLR3E,CATSPERG,DDIT3,RBP1 |
| 6.295e-04 | -7.37 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | MSigDB lists | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | 105 | 26 | 17758 | 2279 |
FADS1,NPAS2,PPARG,TEAD1,TNFRSF21,PPARGC1B,MED27,MED13L,SMARCD3,MED18,MED16,CPT1A,ANGPTL4,PLIN2,TRIB3,NRF1,SREBF2,ACOX1,ARNTL,MED24,ME1,NCOR1,MED20,TBL1X,FDFT1,HMGCR |
| 6.308e-04 | -7.37 | SUMO E3 ligases SUMOylate target proteins | REACTOME pathways | R-HSA-3108232 | 74 | 21 | 8202 | 1117 |
HERC2,STAG1,XPC,SCMH1,SUMO3,BRCA1,NUP43,NUP214,NUP160,RING1,POM121,RPA1,PHC2,RANBP2,NUP133,NSMCE2,NSMCE1,RNF2,XRCC4,BMI1,SEH1L |
| 6.308e-04 | -7.37 | SUMOylation of DNA damage response and repair proteins | REACTOME pathways | R-HSA-3108214 | 74 | 21 | 8202 | 1117 |
HERC2,STAG1,XPC,SCMH1,SUMO3,BRCA1,NUP43,NUP214,NUP160,RING1,POM121,RPA1,PHC2,RANBP2,NUP133,NSMCE2,NSMCE1,RNF2,XRCC4,BMI1,SEH1L |
| 6.352e-04 | -7.36 | LMNA (lamin A/C) | protein interactions | 4000 | 219 | 49 | 16036 | 2270 |
UNC13D,USP7,C9orf78,CUL7,FN1,URB2,TFIP11,SIRT7,ZNF280C,CCDC47,PRKCA,PDCD5,POM121,TOX4,FAM192A,SRPRB,ZNF239,NUP133,UCHL5,MYC,BANF1,GPATCH1,SHMT2,SRRM2,HNRNPM,TMPO,SIRT6,WDR18,PCMT1,RANGAP1,SUPT5H,NUP214,SAP30BP,ISG15,RPA1,SMAD3,DDX3X,RANBP2,GTF2A1,HNRNPR,DNAJC1,LEMD3,TMEM230,H2AFX,CDKAL1,SVIL,FUS,KIAA0196,USP15 |
| 6.385e-04 | -7.36 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | MSigDB lists | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | 21 | 9 | 17758 | 2279 |
NARS2,GARS,WARS2,LARS2,RARS2,AARS2,FARS2,HARS2,YARS2 |
| 6.385e-04 | -7.36 | MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_5 | MSigDB lists | MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_5 | 21 | 9 | 17758 | 2279 |
ACADS,DNAJA4,ATF4,STC2,MBTD1,ME1,MLH1,ADK,TARS |
| 6.389e-04 | -7.36 | RNA polyadenylation | biological process | GO:0043631 | 29 | 11 | 16441 | 2138 |
PAF1,SSU72,PAPD4,PABPC1L,CPSF3,WDR33,AHCYL1,SYMPK,ZC3H3,PABPC1,CDC73 |
| 6.403e-04 | -7.35 | GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN | MSigDB lists | GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN | 180 | 39 | 17758 | 2279 |
TNNC1,USP7,ZNF786,SSH2,RAB11FIP4,WDR74,TRPM6,TRAK1,ZNF346,PRPF39,ZNF44,RPAIN,SEMA6A,TMCO6,SKI,RNF141,SYN2,STC2,SUCLG2,SEH1L,TMLHE,TLCD1,SETD1B,TOP3A,ZNF324B,SLC35D1,PUSL1,S100A16,ZNF655,YIPF2,ZNF557,SDCCAG8,TBX3,SGSM2,ZNF430,UMPS,RPS6KB1,SETD6,TRIM36 |
| 6.407e-04 | -7.35 | MITOCHONDRIAL_PART | MSigDB lists | MITOCHONDRIAL_PART | 139 | 32 | 17758 | 2279 |
BCKDK,MRPL10,OPA1,TIMM10,ETFB,NDUFS7,MRPS11,NDUFV1,ATP5G2,PMPCA,NDUFA6,TOMM34,HTRA2,SLC25A1,TIMM50,TIMM8B,ABCF2,BCS1L,MRPS10,MCL1,POLG2,RHOT2,TIMM44,ATP5D,MFN2,TAMM41,DNAJA3,TIMM17A,SURF1,MPV17,FIS1,SLC25A11 |
| 6.429e-04 | -7.35 | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN | 186 | 40 | 17758 | 2279 |
RTTN,EPM2AIP1,BCKDK,ZNF516,DLGAP4,ZNF280C,TBCCD1,FDX1,ZNF358,TBC1D22A,PPIL2,SOCS6,GPATCH1,PRADC1,FUT11,DENND1A,IPO11,TERF2,USE1,FAM127A,MON1A,IDH3G,ZNF512B,FAM126B,EDEM2,ATP8B2,TRIM37,RBM28,PLCB1,GUF1,VAC14,TPK1,ZNF708,ETFDH,ARL4A,ARNTL,ZAK,SLC25A26,GPATCH4,NR2C2AP |
| 6.429e-04 | -7.35 | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | 186 | 40 | 17758 | 2279 |
BTBD2,KHDRBS1,PCSK7,FAM8A1,MCM9,RSPRY1,KIAA1958,AMPD3,ACD,UBR1,TBC1D22A,ZFYVE28,PPIL2,CLCN6,MED24,PPM1K,ZC3H3,HMBOX1,EVL,BRD4,FBXW4,DDX24,ZFYVE1,PPP1R21,ZNFX1,MEF2D,POLG2,SLC26A11,RPA1,ZNF708,OXSR1,SUFU,INSIG1,CC2D1B,HERC1,VCAN,MKL2,ASB3,AP2S1,TMCC1 |
| 6.429e-04 | -7.35 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 186 | 40 | 17758 | 2279 |
AK2,CHST11,PDE4B,SMAD7,FOSL2,IKBIP,BHLHE40,STAM,MAP2K3,NAMPT,MLX,MBD2,SHMT2,CLDND1,NDUFA6,MYB,SAP30,MTHFD1,PEA15,ANTXR2,PDE4A,EIF3J,LGALS1,PRDM1,MTHFD1L,DLST,TBC1D2,SLC39A14,GNG2,ARHGAP21,ETFDH,ITPRIPL1,RBBP8,IKZF4,ZBTB8OS,IRAK2,DPP4,ANXA2,TESC,LPP |
| 6.437e-04 | -7.35 | V$GR_01 | MSigDB lists | V$GR_01 | 192 | 41 | 17758 | 2279 |
TNNC1,TCF12,CYLD,DLL4,KHDRBS1,LAMTOR3,ATF7IP,ZIC2,ATG2B,IP6K2,BHLHE40,NEDD4,DST,CD96,UBE3A,SLC7A11,UBR1,PAK1IP1,AMOT,KRT20,RANBP6,BDNF,PXN,ZNF654,JMJD1C,PRDM1,CA5B,MBNL2,NCDN,RERE,PAF1,SKIL,NSD1,EIF4ENIF1,SYNCRIP,ADNP,LUC7L3,E2F4,SENP3,DLX2,ZNF532 |
| 6.437e-04 | -7.35 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN | 192 | 41 | 17758 | 2279 |
ARHGAP26,SART1,ATRX,PAFAH1B1,FAM189B,SMG7,LPCAT3,EEA1,PIP4K2A,TMCO6,TERF2IP,RNF40,SLC38A2,BUD31,HIRIP3,LTN1,SELT,ZNF629,SCAF11,BRD4,GPHN,LSM12,HARS,MINA,PSMG1,ATG12,KLF6,RBM28,MBNL2,UBE2K,SAP30BP,MAT2A,DDX3X,KPNA1,SRRD,BBIP1,EIF2S1,SENP3,APAF1,TAF12,RNF130 |
| 6.438e-04 | -7.35 | astrocytoma_Grade_I | COSMIC cancer mutations | astrocytoma_Grade_I | 145 | 33 | 17775 | 2278 |
BRAF,NF1,ATRX,ATF7IP,BCOR,ABCA12,TBC1D22A,PDE10A,CLCN6,MET,KIAA1549,DENND1A,CEP128,NRAS,GARS,PTBP2,THSD4,PRDM16,AGAP1,NAALADL2,FGFR1,RAD54B,DOT1L,GNAI1,TPK1,LRP1B,NME7,KLF4,ATM,KIAA1328,RNF130,NRP1,PARD3 |
| 6.450e-04 | -7.35 | SCN2B (sodium channel, voltage gated, type II beta subunit) | protein interactions | 6327 | 86 | 24 | 16036 | 2270 |
DNM3,EXOC6B,TTI1,OPA1,XPO7,NUP160,BZW2,SLC39A11,EXOC6,EXOC1,THADA,SCN1B,FAM114A2,ORC5,PDS5B,ATM,TNPO3,MDN1,HEATR1,NR2F2,EIF2B3,XPO6,IPO4,IPO11 |
| 6.462e-04 | -7.34 | mRNA 5'-UTR binding | molecular function | GO:0048027 | 7 | 5 | 16491 | 2164 |
DDX3X,IGF2BP2,IGF2BP1,MRPS11,IGF2BP3 |
| 6.463e-04 | -7.34 | VAMP8 (vesicle associated membrane protein 8) | protein interactions | 8673 | 31 | 12 | 16036 | 2270 |
STX8,FN1,STX1A,STAMBP,SNAP23,STX18,DTNBP1,VTI1A,SNAP25,MLH1,NAPA,CEP170 |
| 6.488e-04 | -7.34 | HIST2H3C (histone cluster 2, H3c) | protein interactions | 126961 | 91 | 25 | 16036 | 2270 |
CUL7,BRD4,KMT2D,FN1,SETD1B,ATRX,ELP3,SMARCA4,WDHD1,BRCA1,SETD7,KMT2C,RPS6KA5,KDM1A,CHAF1A,SNCA,RERE,DOT1L,EHMT2,KDM2A,H2AFX,TBL1X,KMT2A,KDM4C,KAT6A |
| 6.571e-04 | -7.33 | RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) | protein interactions | 5970 | 276 | 59 | 16036 | 2270 |
USP7,COMMD10,HMGA2,BANP,NCOR2,EGR1,TAF1,DPF2,CSNK2A1,RPS6KA5,RAC3,HSPA1A,IQGAP2,RIOK2,KDM2A,SOCS1,MYC,IKBKB,SOCS6,RELB,RNF2,PRMT5,CARM1,DIS3L2,DPF3,AKAP8L,PPARG,SIRT6,CDK4,HSPA5,EHMT1,POU2F1,BRCA1,SETD7,MEN1,UBC,UBE2E1,POLR2A,PEX1,ANXA1,SMAD3,TRIB3,NSD1,MYBBP1A,TP53BP1,HIF1A,CDK9,KLF4,DNAJA3,CEBPZ,CUL2,MED15,ATM,FUS,TBL1X,NFKBIB,TXN2,SETD6,PDCD11 |
| 6.582e-04 | -7.33 | cyclic nucleotide catabolic process | biological process | GO:0009214 | 17 | 8 | 16441 | 2138 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 6.606e-04 | -7.32 | TCEA1 (transcription elongation factor A (SII), 1) | protein interactions | 6917 | 62 | 19 | 16036 | 2270 |
BCCIP,WDR61,SUPT6H,LDHA,MCM2,ZMAT2,UBR5,CDC73,POLR2A,PGD,METTL16,PAF1,DUS3L,CDK9,MCM5,DUSP19,GTF2H1,CTR9,SF3A1 |
| 6.611e-04 | -7.32 | HALLMARK_CHOLESTEROL_HOMEOSTASIS | MSigDB lists | HALLMARK_CHOLESTEROL_HOMEOSTASIS | 73 | 20 | 17758 | 2279 |
ANTXR2,MVK,ACTG1,PPARG,ECH1,GNAI1,TRIB3,LSS,JAG1,IDI1,SREBF2,ATXN2,FDPS,ANXA5,SQLE,CLU,ERRFI1,DHCR7,FDFT1,HMGCR |
| 6.611e-04 | -7.32 | GCM_SUFU | MSigDB lists | GCM_SUFU | 73 | 20 | 17758 | 2279 |
ANKRD17,AARS2,ZFP14,MARCH6,IKBKAP,TRAPPC6B,FOXO3,POGZ,EIF4ENIF1,SPAG9,SUFU,KIDINS220,LUC7L3,DCTN4,VPS52,CELF1,TBCK,DMTF1,CEP170,PKNOX1 |
| 6.641e-04 | -7.32 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | 272 | 54 | 17758 | 2279 |
HMGA2,ADAM19,FN1,CCDC58,UROD,ID2,MYH9,PHGDH,CMTM3,PELP1,NDUFS7,DCTPP1,ZBED2,ATG3,MCM5,ANAPC11,ME1,VCL,LSM10,CAV2,N4BP2,TRIP13,RABEPK,PTPRK,TMPO,LAMA4,PEA15,BDNF,RFC4,TUBA1A,KRT7,STAG1,CRIM1,MED27,PSMC3IP,VSNL1,PSMA1,AKAP12,LRRC8A,SLC35F2,CAV1,DKC1,PALLD,SOX4,MGST1,INF2,SYNCRIP,POLE2,PMEPA1,VCAN,EIF2S1,PUS1,TPM1,GPATCH4 |
| 6.760e-04 | -7.30 | ATGAAGG,MIR-205 | MSigDB lists | ATGAAGG,MIR-205 | 151 | 34 | 17758 | 2279 |
DMXL2,SNX27,TRPM2,PAFAH1B1,NHS,SBF2,SMG7,NECAP1,PHC2,CHN1,PRKCE,BUD31,SELT,ETF1,ERRFI1,AMOT,LPCAT1,SEH1L,ZCCHC14,GPM6A,LAMC1,TEAD1,PTPRM,SCMH1,ST6GALNAC3,CAMSAP2,SATB2,PDE3B,PLCB1,SQLE,SEPT5,MAGI1,KIF1B,GPATCH4 |
| 6.799e-04 | -7.29 | positive regulation of biosynthetic process | biological process | GO:0009891 | 1796 | 278 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,PRKCA,ABHD6,GABPB2,LPIN1,NOS1AP,SKI,GIPR,SREBF2,ZFHX3,WIZ,RNF111,ZNF148,MEIS3,DDN,HMBOX1,NR6A1,GNL3,NFIA,TCEB3,CUX1,AKAP12,SUPT20H,STOML2,DDX3X,DDAH2,BRCA2,SUPT4H1,CCNT1,RUNX1,RFXAP,P2RY11,MEF2C,BANP,EPM2AIP1,EGR1,JUP,KHDRBS1,SIRT7,PID1,RSF1,CDC73,MYC,MED24,PABPC1,MYB,GTF2H3,BDNF,WDR61,STAG1,RREB1,PRDM16,ARID5B,SMARCD3,ARID1A,NELFA,PLCB1,TRIM37,ONECUT2,ABCF1,IRS1,CAT,TASP1,HIF1A,CDK9,SPEN,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SHC1,ACD,WAC,LPIN2,KMT2A,KMT2D,BRD4,SATB2,MED16,MEF2D,SETD7,ERC1,SERP1,SNCA,VDR,TAF2,SMARCC1,HIPK2,PEMT,RPS6KB1,HMGA2,INSIG2,TCF3,ID2,TRIM22,TGFB2,RPS6KA5,FOXO3,MAD2L2,SFR1,TADA3,SNW1,TRIAP1,YBX3,LARP4B,SAMD4A,SOX6,MBTPS2,SLC40A1,IL6R,KLF6,GUF1,FOXC1,UBC,POLR2A,ANXA1,NSD1,ARID3B,BMP4,IGBP1,UQCC1,DDIT3,KAT6A,TRIM16,ATRX,NF1,KMT2E,GPBP1L1,AAMDC,PPARGC1B,SIRT2,MAP2K3,SMARCB1,PHF5A,DHX33,ZEB1,RELB,RAN,ETV1,TRIM14,ZBTB17,DEAF1,TRIM13,ATF4,RBCK1,PPARG,CDK4,HSPA5,BRCA1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,TNFRSF1A,DLX2,CLU,ZC3H8,UQCC2,FOXO1,TAF1,PAX2,SMAD7,TRIM15,ZIC2,BARX2,RLF,ARID1B,NAMPT,ELL,SUB1,CEP290,BUD31,CTR9,GTF2H1,ICE2,NRIP1,NT5E,CAMKK2,PAXBP1,UTP15,EIF2A,SUPT5H,TCF7L2,NR2F1,ATXN7,IRAK2,ZFP90,TBL1X,TESC,TCF12,ASH1L,NTSR1,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,NRF1,RRN3,JAG1,CAMTA2,NVL,IKBKB,MET,CTC1,MAML3,MOSPD1,KAT8,DDX41,GRHL3,ATXN1,DKC1,SMAD3,IKZF4,ADNP,SIX5,KLF4,COPS5,CEBPZ,ARNTL,PUS1,SCARB1,HEATR1,PKIB,DNAJC2,MAP3K13,SUPT6H,CAMK1,AGO2,ATF7IP,BMP6,PTPN2,PRKCH,HAS3,UTS2,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,FGF2,ZNF821,KDM5A,SMARCAD1,MEN1,HSPA1B,MKX,RERE,TBX3,TAF4,BCAS3,CSRNP1,FNTB,NCBP2,MYRF,TAF12,RBPJ,NR2F2,NFKBIB,HRH1 |
| 6.849e-04 | -7.29 | MORF_XRCC5 | MSigDB lists | MORF_XRCC5 | 229 | 47 | 17758 | 2279 |
MCM6,PRPF31,PTPRA,KHDRBS1,DDX19A,XPO7,HDDC2,POM121,PABPC4,NDUFV1,SRSF2,SREBF2,SSBP1,YARS,GNG5,HNRNPM,NUDC,IFRD1,CAMKK2,SKIV2L2,NARS,WDR18,PCMT1,R3HDM1,PSMA1,TMEM123,MCM2,DKC1,DDX49,POLR2A,ARIH2,EIF3H,CHAF1A,ARPC3,EPRS,TRRAP,CDC16,SMARCC1,HNRNPR,COQ9,TIMM17A,SET,ACP1,GPN1,NDUFS5,TROVE2,SRP14 |
| 6.930e-04 | -7.27 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 1697 | 264 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,PRKCA,GABPB2,LPIN1,SKI,GIPR,SREBF2,ZFHX3,WIZ,RNF111,ZNF148,MEIS3,DDN,HMBOX1,NR6A1,GNL3,EYA3,NFIA,TCEB3,CUX1,AKAP12,SUPT20H,STOML2,DDX3X,BRCA2,SUPT4H1,CCNT1,RUNX1,RFXAP,P2RY11,MEF2C,BANP,EGR1,JUP,SIRT7,PID1,RSF1,CDC73,RBM20,ENTPD5,APLF,MYC,MED24,PABPC1,TERF2,MYB,GTF2H3,BDNF,WDR61,STAG1,RREB1,PRDM16,ARID5B,SMARCD3,ARID1A,NELFA,PLCB1,TRIM37,ONECUT2,CAT,TASP1,HIF1A,CDK9,SPEN,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SLX4,SHC1,ACD,WAC,LPIN2,KMT2A,KMT2D,BRD4,SATB2,MED16,MEF2D,SETD7,ERC1,VDR,TAF2,SMARCC1,HIPK2,H2AFX,BRCC3,HMGA2,INSIG2,TCF3,ID2,TRIM22,RPS6KA5,FOXO3,MAD2L2,SFR1,TADA3,SNW1,TRIAP1,SOX6,MBTPS2,SLC40A1,APEX1,IL6R,KLF6,FOXC1,UBC,POLR2A,NSD1,ARID3B,BMP4,IGBP1,DDIT3,KAT6A,TRIM16,ATRX,NF1,KMT2E,GPBP1L1,AAMDC,PPARGC1B,SIRT2,HNRNPLL,MAP2K3,SMARCB1,PHF5A,DHX33,ZEB1,RELB,RAN,ETV1,TRIM14,ZBTB17,DEAF1,TRIM13,ATF4,RBCK1,PPARG,HSPA5,BRCA1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,TNFRSF1A,DLX2,CLU,ZC3H8,FOXO1,TAF1,PAX2,SMAD7,TRIM15,ZIC2,BARX2,RLF,ARID1B,NAMPT,SUB1,ELL,CEP290,BUD31,CTR9,VAPB,GTF2H1,ICE2,NRIP1,CAMKK2,PAXBP1,UTP15,EIF2A,SUPT5H,TCF7L2,ATXN7,IRAK2,ZFP90,TBL1X,TESC,TCF12,ASH1L,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,NRF1,RRN3,JAG1,BRE,CAMTA2,NVL,IKBKB,MET,SPIDR,CTC1,MAML3,PRPF19,MOSPD1,KAT8,DDX41,GRHL3,ATXN1,DKC1,SMAD3,IKZF4,SIX5,ADNP,KLF4,COPS5,CEBPZ,ARNTL,HEATR1,PUS1,PKIB,DNAJC2,MAP3K13,SUPT6H,CAMK1,AGO2,ATF7IP,BMP6,PRKCH,HAS3,TMEM161A,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,ZNF821,FGF2,KDM5A,SMARCAD1,MEN1,HSPA1B,RERE,TBX3,TAF4,BCAS3,CSRNP1,NCBP2,TAF12,RBPJ,MYRF,NR2F2,NFKBIB,HRH1 |
| 6.998e-04 | -7.26 | MORF_PSMF1 | MSigDB lists | MORF_PSMF1 | 163 | 36 | 17758 | 2279 |
EP400,ATRX,NFX1,KLHL18,BARX2,TTI1,RPS6KA5,PSMF1,MGA,TBC1D22A,CACNB2,NCKIPSD,ZNF710,MICAL3,ZBTB17,CHD9,TTLL5,SULT4A1,KIAA0586,BRCA1,ERC1,PIK3CB,HTR7,TAF2,CACNB1,RBBP8,SLC30A3,KIAA0355,CHD3,MSH3,FNTB,ZNF32,ARHGAP12,RUNX1,SMG1,TMCC1 |
| 7.010e-04 | -7.26 | GFPT1 (glutamine--fructose-6-phosphate transaminase 1) | protein interactions | 2673 | 53 | 17 | 16036 | 2270 |
CARS,GARS,TTC27,SIRT6,PRKAB2,SIRT7,MARS,PRKCA,XPO7,TARS,TTC1,CAD,ASNS,ARHGAP1,NMD3,PRMT3,TROVE2 |
| 7.012e-04 | -7.26 | PES1 (pescadillo ribosomal biogenesis factor 1) | protein interactions | 23481 | 67 | 20 | 16036 | 2270 |
SNU13,NIFK,CUL7,DDX24,UTP14A,GNL3,SIRT7,GNL1,RBM28,PUM3,NOP56,PES1,PWP1,MYC,CEBPZ,RNF2,NOC3L,FBL,BLMH,FTSJ3 |
| 7.022e-04 | -7.26 | regulation of transcription from RNA polymerase II promoter | biological process | GO:0006357 | 1740 | 270 | 16441 | 2138 |
ZNF292,HLTF,CCNL2,GABPB2,LPIN1,SKI,SREBF2,ZFHX3,RNF111,ZNF148,FNIP2,CHD2,MEIS3,DDN,NR6A1,GNL3,EHMT1,NFIA,TCEB3,CUX1,RFX2,SUPT20H,SPOP,GZF1,DDX3X,SKIL,SUPT4H1,SSU72,CCNT1,RUNX1,BMI1,MEF2C,WDR75,EGR1,JUP,ZHX3,SIRT7,GTF2IRD1,PID1,CDC73,CHD5,MYC,MED24,ZNF518B,MYB,ZNF675,GATAD2B,GTF2H3,WDR61,STAG1,RREB1,PRDM16,POLA1,ARID5B,RYR2,SMARCD3,ARID1A,NELFA,TRIM37,ONECUT2,ZNF783,EHMT2,HIF1A,CDK9,SPEN,MED15,PURB,NCOR1,SMYD3,ZNF254,MAP2K5,TRERF1,NPAS2,FOSL2,BLOC1S2,PPID,LPIN2,KMT2A,CDK12,SAP30,KMT2D,BRD4,SATB2,MED16,MEF2D,FGFR1,SNCA,VDR,TAF2,MSX2,CAMK2D,SMARCC1,ELP2,HIPK2,DNAJA3,YEATS2,HMGA2,NCOR2,INSIG2,TCF3,TRAK1,NFX1,ID2,BHLHE40,IKBKAP,RPS6KA5,FOXO3,MAD2L2,NEDD4,TADA3,SNW1,SUV39H2,TAF3,TRIAP1,YBX3,ZNF710,SOX6,MBTPS2,SLC40A1,FGF9,KLF6,FOXC1,UBC,TRIB3,SRCAP,NSD1,ARID3B,BMP4,BRWD3,IGBP1,DDIT3,KDM4C,ZNF76,ATRX,UBN1,AAMDC,PPARGC1B,SIRT2,BCOR,SMARCB1,ECM1,YLPM1,JAZF1,ZEB1,RELB,ETV1,HCFC2,DEAF1,ATF4,AEBP2,PPARG,MED27,HSPA5,MINA,HDAC8,BRCA1,CAV1,SOX4,TAF9B,MLLT10,PAF1,TCF7L1,GATA6,SUFU,INSIG1,TP53BP1,CC2D1B,CHD3,E2F4,PER1,MKL2,TNFRSF1A,DLX2,BEND6,ZC3H8,USP15,FOXO1,TAF1,PAX2,SMAD7,HES6,MED13L,BARX2,RLF,NAMPT,SUB1,ELL,MLX,ZNF354A,VPS72,MBD2,SAMD11,BUD31,TIMELESS,CTR9,GTF2H1,NRIP1,PAXBP1,ELP3,WWC1,PRDM1,EIF2A,SUPT5H,TCF7L2,NR2F1,ATXN7,ZFP90,TBL1X,N4BP2L2,TCF12,ASH1L,ID1,DLL4,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,ZSCAN5A,NRF1,JAG1,CAMTA2,IKBKB,RNF2,MET,MAML3,MOSPD1,DDX41,TFCP2,GRHL3,ATXN1,BATF3,SMAD3,RBBP8,IKZF4,SIX5,KLF4,COPS5,CEBPZ,ARNTL,PUS1,ZNF18,MED20,SUPT6H,CAMK1,RFX1,AGO2,ATF7IP,MED18,FOXP1,BMP6,DMRT1,PKNOX1,ARNTL2,KDM6B,MSX1,ZNF821,FGF2,ZMYM5,MEN1,PDE2A,DKK1,MKX,RERE,CUL2,TBX3,BCAS3,CSRNP1,RBPJ,NR2F2 |
| 7.036e-04 | -7.26 | GERHOLD_ADIPOGENESIS_DN | MSigDB lists | GERHOLD_ADIPOGENESIS_DN | 63 | 18 | 17758 | 2279 |
IFRD1,IL11RA,FN1,TUBA1A,EIF3C,CDK4,GAS6,SOX4,VDR,UBTF,ECM1,VCAN,MMP14,ANXA5,ZNF148,ANXA2,CD44,CDC37 |
| 7.084e-04 | -7.25 | BROWNE_HCMV_INFECTION_10HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_10HR_DN | 53 | 16 | 17758 | 2279 |
RANBP6,BDNF,RHOBTB1,STAMBP,PNN,SON,MGA,TCF7L2,MTUS1,RDH11,IGF2BP3,IRS1,RUNX1,ETV1,OGG1,NT5E |
| 7.122e-04 | -7.25 | YAGI_AML_WITH_11Q23_REARRANGED | MSigDB lists | YAGI_AML_WITH_11Q23_REARRANGED | 336 | 64 | 17758 | 2279 |
DMXL2,THOC5,UBN1,PAFAH1B1,MYH9,POP5,ST3GAL6,CSTA,STAM,NDUFB3,CAMTA2,S100A10,PPID,KIAA0922,SPAG6,GPM6A,NARS,TFPI,LGALS1,ATXN1,ZNF91,WARS,GNAI1,SLC7A1,RANBP2,DDAH2,ABHD3,VPS13D,DPP4,SEMA3C,TBXA2R,BMI1,MEF2C,HMGA2,CARS,AK2,CAMK1,MED13L,IKBKAP,MBNL1,SFI1,IGF2BP3,ADH5,EIF2S2,ANXA5,CLDND1,GMDS,SAMD4A,RANBP6,ERICH1,CRADD,JMJD1C,IL6R,EXOG,SUPT5H,EVI5,FOXC1,SMPDL3B,CTIF,TPD52L2,FSCN1,CDK9,ATM,DHCR7 |
| 7.132e-04 | -7.25 | DNA repair complex | cellular component | GO:1990391 | 39 | 13 | 17570 | 2233 |
PMS1,SLX4,ZSWIM7,POLE2,XPC,MSH3,LIG4,ATM,MLH1,MSH4,POLE3,XRCC4,KDM1A |
| 7.135e-04 | -7.25 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP | 175 | 38 | 17758 | 2279 |
SEPHS2,RELL2,NDUFA5,THOC5,URB2,DCP1B,POP5,PDCD7,RMI1,URB1,GIT2,EDC3,SFR1,CAD,FLAD1,PSMG4,ZNF561,YLPM1,DHX33,TRIAP1,SLC35C2,TRMT12,IPO11,MCEE,TSHZ1,RANBP6,KIAA0586,NFIA,MRPL36,POP1,PALB2,DNAJA3,ZNF557,TAF4,SLC25A11,PUS1,FAHD1,TBCK |
| 7.137e-04 | -7.25 | POSITIVE_REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT | MSigDB lists | POSITIVE_REGULATION_OF_TRANSCRIPTIONDNA_DEPENDENT | 117 | 28 | 17758 | 2279 |
ATF4,TRERF1,FOXO1,NPAS2,PPARGC1B,TCF3,SMARCD3,ATF7IP,ARID1A,RSF1,SUPT5H,FOXO3,BMP6,MAP2K3,SMAD3,DYRK1B,NSD1,SUPT4H1,SMARCC1,PHF5A,HIF1A,ARNTL,MKL2,TNFRSF1A,GTF2H1,RUNX1,NRIP1,MAML3 |
| 7.145e-04 | -7.24 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 84 | 22 | 17758 | 2279 |
BDNF,PCNT,RB1CC1,PCCA,TFPI,ARHGEF10,SLC25A12,WDR37,SON,CTIF,DKK1,DST,RANBP2,BICD1,PVRL3,CUL2,PDS5B,KIAA0922,PDLIM5,NAV3,VPS13B,TMCC1 |
| 7.157e-04 | -7.24 | regulation of fibroblast proliferation | biological process | GO:0048145 | 83 | 22 | 16441 | 2138 |
NRAS,FN1,SIRT6,PPARG,NF1,CDK4,DDR2,LIG4,GAS6,FOSL2,KMT2C,RNASEH2B,CDC73,SKI,PMAIP1,MYC,FNTB,ANXA2,UTS2,BMI1,CDK6,CTC1 |
| 7.170e-04 | -7.24 | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 181 | 39 | 17758 | 2279 |
ZNF292,ASCC1,BRAF,GRINA,FAM50A,BRE,ARHGAP18,TBC1D22A,SETD5,CFDP1,XRCC2,WDR60,CLDND1,FUT11,PLEKHA2,DDHD1,CHD9,PDK1,RREB1,KDM5B,DDX41,LSM12,ATG12,MAPK1IP1L,ARL5B,SERP1,ABCF1,TAF9B,TBC1D2,ZC3H12A,UBAP2,SPAG9,INSIG1,NSMCE2,C7orf50,TRAF3,RBPJ,NFKBIB,SLC25A26 |
| 7.175e-04 | -7.24 | TERF1 (telomeric repeat binding factor (NIMA-interacting) 1) | protein interactions | 7013 | 300 | 63 | 16036 | 2270 |
SRM,SARS,MVK,BRAF,SULT1C2,RBM33,PRDX6,TRIM16,UTP14A,FANCD2,MYH9,PLOD1,RTN4,ZFP36L1,NOL3,SEC16A,KDM1A,PABPC4,RING1,SBDS,TOX4,TERF2IP,DST,RNF40,ABL1,RPS16,ACD,TMSB10,ANXA5,RNF2,PRMT5,LRSAM1,TOMM34,TERF2,CDC37,SPTAN1,DBN1,EVL,APEX1,STAG1,DDX24,GNL3,ZC3H18,PCMT1,LDHA,RYR2,BRCA1,MCM2,SUPT5H,SAP30BP,WARS,PGD,TAF2,FBXO21,CCNT1,CDK9,SET,HOXA3,TBPL1,ATM,TBL1X,ANXA2,KLHDC4 |
| 7.180e-04 | -7.24 | GSE17721_4H_VS_24H_POLYIC_BMDM_DN | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDM_DN | 193 | 41 | 17758 | 2279 |
CARS,BCCIP,TCF12,ATP6V1A,PRKCSH,PIGH,RIPK1,PRPF39,LYRM2,TMCO6,AMPD3,NPRL2,BCAS2,CAMTA2,ATXN2,BUD31,PPCDC,NDUFA6,FBXO31,AHCYL1,KLRD1,GARS,BRD4,IFNGR2,TSTA3,SFSWAP,TYW1,TEX14,PSMA1,TTYH2,SON,TMEM206,DHX57,SPOP,MLLT10,ZNF622,CTAGE5,TRMT2A,SENP3,RNF130,ARHGAP10 |
| 7.184e-04 | -7.24 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN | 187 | 40 | 17758 | 2279 |
C17orf80,ATP6V1A,DYM,TUBE1,PPIL1,NLE1,RMI1,ETFB,SLC25A20,ZNF239,FLAD1,ASNS,SUV39H2,ARMC6,MCM5,CBR4,HIRIP3,CCDC124,CCDC121,FTSJ3,TIMM50,MTHFD1,SAP30,ARNTL2,WDR36,TMEM126B,ATOX1,SCFD2,WDHD1,PSMG1,STOML2,PAF1,SLC39A14,SLC7A1,DNAJA3,ACOX1,ORC5,ATG7,PAM,MED20 |
| 7.238e-04 | -7.23 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | 349 | 66 | 17758 | 2279 |
USP7,SNX27,ASH1L,ABCA3,UBN1,SPATA2L,ARID2,KIAA0232,PBX1,BCOR,SLC25A44,SEC16A,TMEM150C,TMEM184A,LONRF2,TTC3,SRRM2,DENND1A,EVL,GARS,SLC38A1,BAZ2A,THSD4,PREX1,TBC1D16,PYCR1,DDAH2,KDM4B,DNAJC1,ASTN2,LUC7L3,SYNGR2,CFD,LARGE,PRRT3,MAPT,VIPR1,MIF4GD,DNAJA4,ARFIP2,CLSTN2,PLA2G12A,POGZ,REEP5,SFI1,GART,VPS72,PCK2,LARP4B,LRP3,MYB,TRAPPC9,TLE3,USP42,MARS,ZNF467,ONECUT2,SLC26A11,KLHL22,SERF2,TBX3,HK2,TBL1X,MB21D2,C7orf26,CTXN1 |
| 7.319e-04 | -7.22 | WDR48 (WD repeat domain 48) | protein interactions | 57599 | 72 | 21 | 16036 | 2270 |
PPP1R9B,MYCBP2,SHQ1,SUPT6H,ARHGEF10,CSNK2A1,FAM122B,BRCA1,DKC1,UBR5,USP46,PPP1R9A,AHCYL2,EIF3H,ATAD5,P3H1,YLPM1,SET,GPN1,AHCYL1,YARS |
| 7.353e-04 | -7.22 | response to transforming growth factor beta | biological process | GO:0071559 | 179 | 39 | 16441 | 2138 |
CGN,NCOR2,ID1,SMAD7,TGFB2,TGFBR2,PDCD5,PDE3A,SKI,FKBP1A,SNW1,ZFHX3,MYC,UCHL5,RNF111,SOX6,PTPRK,PXN,GCNT2,FERMT2,CAV1,PTK2,MEN1,PDE2A,UBC,SKIL,SMAD3,CCNT1,PMEPA1,E2F4,HIPK2,CDK9,ADAM9,APAF1,NCOR1,RUNX1,PARD3,MEF2C,USP15 |
| 7.364e-04 | -7.21 | MITOCHONDRIAL_ENVELOPE | MSigDB lists | MITOCHONDRIAL_ENVELOPE | 95 | 24 | 17758 | 2279 |
TIMM8B,ABCF2,BCS1L,MCL1,OPA1,TIMM10,RHOT2,NDUFS7,ATP5D,MFN2,TAMM41,NDUFV1,ATP5G2,TIMM17A,MPV17,SURF1,PMPCA,SLC25A11,FIS1,NDUFA6,TOMM34,HTRA2,SLC25A1,TIMM50 |
| 7.370e-04 | -7.21 | HDAC1 (histone deacetylase 1) | protein interactions | 3065 | 466 | 91 | 16036 | 2270 |
ZNF76,ZNF516,TRERF1,ATRX,PBX1,CSNK2A1,SMARCA4,BCOR,KDM1A,SMARCB1,ZNF827,KCTD11,RAP1A,MAD1L1,ZNF148,RNF2,KDM5C,KMT2A,ZMYM2,SF3A1,SAP30,RFC4,BAZ2A,PPARG,TFCP2,SIRT6,POU2F1,SATB2,VIM,BRCA1,MEF2D,FKBP3,SMAD3,UBTF,SKIL,DNTTIP1,SMARCC1,KPNA3,HNRNPR,CHD3,ADNP,KLF4,E2F4,RUNX1,BRCC3,RBP1,EMSY,BANP,EP400,NCOR2,ESCO1,FN1,RFX1,SMAD7,BHLHE40,CHD5,ADH5,HR,MYC,MBD2,BANF1,NRIP1,PPA1,SOX6,GATAD2B,IFRD1,KDM5B,RREB1,APEX1,TLE3,KDM5A,SMARCAD1,ARID5B,ZNF512B,PRDM1,MEN1,PHF6,POLR3A,MKX,RERE,KPNA1,EHMT2,HIF1A,SPEN,TBX3,ATM,PFDN2,RBPJ,NR2F2,KDM4C,DDIT3 |
| 7.424e-04 | -7.21 | LATS2 (large tumor suppressor kinase 2) | protein interactions | 26524 | 149 | 36 | 16036 | 2270 |
CGN,TBKBP1,CUL7,AMOTL1,CYLD,LETM1,PPP2R2A,PLOD1,CSPP1,TUBB6,SEC16A,NUP160,RADIL,ABL1,ANAPC1,SIPA1L3,KIAA1671,PPFIBP1,ALDH18A1,CCDC88C,AMOT,KIAA1549,LONP1,PHLDB2,CEP295,WWC1,TRIM37,ERC1,EIF4ENIF1,NME7,DNAJA3,MAGI1,MIPOL1,PARD3,PTPN14,STK4 |
| 7.434e-04 | -7.20 | RNA secondary structure unwinding | biological process | GO:0010501 | 43 | 14 | 16441 | 2138 |
DDX3X,DDX28,DDX56,DDX50,DDX41,DDX24,DDX18,DDX19A,EIF4A2,AGO2,DDX31,DDX10,DDX49,AGO3 |
| 7.521e-04 | -7.19 | rRNA processing | biological process | GO:0006364 | 150 | 34 | 16441 | 2138 |
SART1,UTP14A,SBDS,NOP56,MRPS11,METTL16,CHD7,DDX56,RPS16,MPHOSPH10,ERI1,EXOSC4,GEMIN4,ERI3,FBL,UTP4,FTSJ3,DIS3L2,WDR36,EXOSC2,SKIV2L2,NPM3,NOL8,NOL6,UTP15,WBSCR22,METTL15,DKC1,NOP58,PES1,SRFBP1,HEATR1,NOLC1,PDCD11 |
| 7.588e-04 | -7.18 | organophosphate catabolic process | biological process | GO:0046434 | 116 | 28 | 16441 | 2138 |
PRDX6,PDE4A,ITPA,UPP1,NTSR1,GPCPD1,PDE4B,PDE2A,NUDT15,PDE3B,INPP1,SYNJ1,ABHD6,NAPEPLD,SMPDL3B,PDE3A,PDE8B,DCTPP1,CAT,HPRT1,AMPD3,PDE10A,NT5C,NT5M,MUTYH,PDE9A,OGG1,NT5E |
| 7.640e-04 | -7.18 | SCHLOSSER_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_DN | 681 | 116 | 17758 | 2279 |
PTP4A1,TCF12,DMXL2,ADAM19,MYCBP2,NDUFA5,PHF3,MAP2K5,CUL4A,PAFAH1B1,PDK4,RCHY1,ISG20L2,RNF24,HLTF,SSBP2,PTPRG,NUP160,PIBF1,DECR1,RAP1A,JAG1,IDI1,MMP7,ASNS,PMAIP1,RABGAP1L,CBR4,ANAPC10,MRPS27,SOCS6,PDS5B,HIBCH,PRKACB,PTPRK,SEC24A,GPM6A,ATF4,BAZ2A,KLHL23,HSPA5,PCMT1,GMFB,R3HDM1,AKAP12,TMEM123,EIF3H,WARS,EXO1,INSIG1,HNRNPR,LSM14A,KLF4,COPS5,ABHD3,WDR7,BBIP1,PPP3CC,BMI1,SERINC5,STX8,SEC24D,SLK,TCF3,RTN4,PHGDH,CLINT1,MBNL1,FAM8A1,TOX4,ADH5,ABL1,SUB1,UBE3A,EIF2S2,ANXA7,USPL1,PVRL3,MBD2,IFIT5,UPF2,SNAPC5,SERBP1,FDFT1,HMGCR,ADARB1,LAMC1,PRIM2,CRIM1,RB1CC1,TRA2A,ABCF2,RAP1B,PSMA1,PPIP5K2,CYB5B,EVI5,UBC,ECH1,PGD,CAT,MGAT2,KIDINS220,SERINC1,SET,RIOK3,SQLE,GPN1,NCBP2,APAF1,PTP4A2,ADK,MTMR1,IGBP1,MAP2K4,HS2ST1 |
| 7.654e-04 | -7.18 | POSITIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | MSigDB lists | POSITIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | 152 | 34 | 17758 | 2279 |
EGR1,TRERF1,FOXO1,NPAS2,PPARGC1B,TCF3,ATF7IP,RSF1,FOXO3,BMP6,MAP2K3,PHF5A,PSMG4,GTF2H1,NRIP1,MAML3,KAT8,ATF4,CAMKK2,KDM5A,SMARCD3,ARID1A,SUPT5H,DYRK1B,SMAD3,NSD1,SUPT4H1,SMARCC1,HIF1A,MKL2,ARNTL,TNFRSF1A,RUNX1,KAT6A |
| 7.728e-04 | -7.17 | DPF2 (D4, zinc and double PHD fingers family 2) | protein interactions | 5977 | 40 | 14 | 16036 | 2270 |
SMARCC1,TP53BP1,DDX18,COPS5,BANF1,RELB,SMARCD3,SMARCA4,RNF2,UPF2,ARID1A,BMI1,ARID1B,SMARCB1 |
| 7.731e-04 | -7.17 | TFAP4 (transcription factor AP-4 (activating enhancer binding protein 4)) | protein interactions | 7023 | 87 | 24 | 16036 | 2270 |
APEX1,ZHX3,TFCP2,ARID2,PARP2,PRDM16,EHMT1,NFIA,BRCA1,ARID1A,NR2F1,SMARCB1,TERF2IP,DNTTIP1,EHMT2,POLE2,MBD2,WIZ,RAN,NR2F2,YEATS2,PKNOX1,TERF2,NAV3 |
| 7.800e-04 | -7.16 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 318 | 61 | 17758 | 2279 |
SEPHS2,GGT1,SPRED2,FAM208B,FEM1C,TNFRSF21,C16orf45,ARFIP2,IGF2BP2,TUBB6,PDCD5,REEP5,ETFB,NEDD4,MTUS1,RNF141,IDI1,ABCA12,ZKSCAN1,PMAIP1,MYC,BCAP29,CLDND1,MFAP2,FBL,PRKACB,FDFT1,HMGCR,ARNTL2,DSC3,NRAS,KRT7,TSTA3,LIMA1,SLC38A1,KCNMA1,FOXC1,TCF7L2,NR2F1,STOML2,GLS,RETSAT,MSX2,HPRT1,RBBP8,SYNCRIP,PDLIM1,KDM4B,DCXR,G6PD,RNF138,PAM,SLC16A1,CLU,ECHDC1,TMEM158,MID1,YEATS2,MAPT,TRIM36,GALE |
| 7.807e-04 | -7.16 | snRNA metabolic process | biological process | GO:0016073 | 34 | 12 | 16441 | 2138 |
ELL,EXOSC2,INTS7,INTS5,INTS9,INTS12,ICE2,EXOSC4,ZC3H8,DKC1,SNAPC4,CPSF3L |
| 7.883e-04 | -7.15 | amide biosynthetic process | biological process | GO:0043604 | 468 | 85 | 16441 | 2138 |
GGT1,EIF3C,RARS2,AARS2,MRPL10,RPS29,CERS5,ST3GAL6,AARS,PABPC4,DENR,MRPS30,CAD,SRPRB,FARSA,MMP7,RPS16,ASNS,MRPS27,ETF1,YARS,MTHFD2L,NARS2,GARS,EIF4E3,NARS,HARS,EIF3J,MTIF2,MRRF,MTHFD1L,ST3GAL5,EIF3H,WARS,DDX3X,EEFSEC,COPS5,BDH2,FTSJ1,EIF2B3,CARS,SARS,LARS2,AGO2,FARS2,VARS,SSR4,GFM2,YARS2,IGF2BP3,MRPS11,EIF2S2,GART,GATC,ATIC,HARS2,SELT,MRPL21,PPA1,PABPC1,RPL22L1,MTHFD1,RPS6KB2,GTF2H3,WARS2,EIF4A2,MRPS10,ST6GALNAC3,MARS,EIF2A,EIF5B,GUF1,ABCF1,TARS,MRPL36,EPRS,RARS,MTHFD2,RPL28,SRP68,EIF2S1,CDKAL1,GGT7,CNDP2,SRP14 |
| 7.907e-04 | -7.14 | NON_MEMBRANE_BOUND_ORGANELLE | MSigDB lists | NON_MEMBRANE_BOUND_ORGANELLE | 614 | 106 | 17758 | 2279 |
POLB,ACTG1,ATRX,PAFAH1B1,KIF5A,ACTR3,MRPL10,MYH9,TUBE1,SIRT2,CSTA,FLNB,RPGRIP1L,NOP56,TERF2IP,RPP30,MPHOSPH10,ACD,IPP,CORO1A,RAN,CEP63,LYST,TMPO,RFC4,RFC3,LIMA1,GNL3,NOL8,NOL6,KIF15,DLG4,SUMO3,HDAC8,VIM,PNN,DKC1,MCM2,POLG2,DSP,SERP1,STOML2,ARPC3,UBTF,CDC16,BRCA2,CCNT1,PAM,TPM1,NOLC1,XRCC4,SYNPO,MID1,MAPT,DCTN3,TNNC1,TTN,MAP1S,KIF5C,EVPL,IKBKAP,NOL3,ZNF346,MRPS11,IQGAP2,ABL1,DDX56,SUV39H2,CEP290,DCTN4,TIMELESS,GEMIN4,AMOT,POLR1E,PNMA1,TERF2,NOM1,SPTAN1,TOP1,PXN,DDX24,APEX1,POLA1,ELP3,TPM4,LIG4,MRPS10,PTK2,APTX,OASL,PALLD,NOP58,FOXC1,POLR2A,RPA1,ANXA1,POP1,MYBBP1A,FSCN1,ZNF330,SRP68,PURB,RBPJ,POLR1C,PDLIM5,KIF1B |
| 7.907e-04 | -7.14 | INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE | MSigDB lists | INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE | 614 | 106 | 17758 | 2279 |
POLB,ACTG1,ATRX,PAFAH1B1,KIF5A,ACTR3,MRPL10,MYH9,TUBE1,SIRT2,CSTA,FLNB,RPGRIP1L,NOP56,TERF2IP,RPP30,MPHOSPH10,ACD,IPP,CORO1A,CEP63,RAN,LYST,TMPO,RFC4,RFC3,LIMA1,GNL3,NOL8,NOL6,KIF15,DLG4,SUMO3,VIM,HDAC8,PNN,DKC1,MCM2,DSP,POLG2,SERP1,STOML2,ARPC3,UBTF,CDC16,BRCA2,CCNT1,PAM,TPM1,NOLC1,XRCC4,MID1,SYNPO,MAPT,DCTN3,TNNC1,TTN,MAP1S,KIF5C,EVPL,ZNF346,NOL3,IKBKAP,IQGAP2,MRPS11,ABL1,DDX56,SUV39H2,CEP290,DCTN4,TIMELESS,GEMIN4,AMOT,PNMA1,POLR1E,TERF2,TOP1,SPTAN1,NOM1,PXN,APEX1,DDX24,POLA1,ELP3,TPM4,MRPS10,LIG4,APTX,PTK2,OASL,PALLD,NOP58,FOXC1,POLR2A,RPA1,ANXA1,POP1,MYBBP1A,FSCN1,ZNF330,SRP68,PURB,RBPJ,POLR1C,PDLIM5,KIF1B |
| 7.951e-04 | -7.14 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | 170 | 37 | 17758 | 2279 |
VIPR1,PTP4A1,SERINC5,PCNT,RBM33,ITPRIP,H2AFJ,ST7L,FOSL2,TIGD1,FAM8A1,CNST,S100A10,FHIT,PERP,SNX29,IL11RA,TSPYL4,PTPRM,RAP1GAP2,ARRDC3,MEF2D,PDE2A,SOX4,MBNL2,ST3GAL5,TCF7L2,PLCXD2,NAP1L5,SKIL,AHNAK,ZDHHC11,HELZ,KLF4,AGTPBP1,C3orf35,PPP3CC |
| 7.960e-04 | -7.14 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 200 | 42 | 17758 | 2279 |
CARS,POLB,SLC2A1,OLA1,JMJD6,PLA2G12A,CHCHD10,RCAN1,BHLHE40,RNASEH2B,DDIT4,DECR1,IDI1,NVL,AGL,FDFT1,SAP30,HMGCR,RFC4,AEBP2,SKAP2,PRIM2,LGALS1,MINA,RNH1,CYB5B,HERPUD1,TAMM41,TRIB3,TPD52L2,AHNAK,MTHFD2,FDPS,HK2,CRCP,XPNPEP1,SQLE,HMBS,ANXA2,RBPJ,BLMH,DHCR7 |
| 7.960e-04 | -7.14 | MORF_AATF | MSigDB lists | MORF_AATF | 200 | 42 | 17758 | 2279 |
DDX18,PRPF31,PRKCSH,KHDRBS1,VARS,POP5,XPO7,POM121,PABPC4,TERF2IP,CAD,MCM5,ETF1,SSBP1,POLE3,SERBP1,NUDC,KDM3B,SFSWAP,WDR18,ADSL,BMS1,MCM2,DDX49,SERP1,CLNS1A,ARIH2,POLR2A,MFN2,PWP1,EPRS,TRRAP,TP53BP1,TIMM17A,COPS5,COQ9,SET,CEBPZ,GPN1,SCARB1,COPS6,XPO6 |
| 7.977e-04 | -7.13 | MORF_ERCC2 | MSigDB lists | MORF_ERCC2 | 101 | 25 | 17758 | 2279 |
SIK3,CHD9,ATRX,SFSWAP,KIAA0586,KLHL18,TTI1,EIF5B,DENND4A,PIK3CB,PSMF1,RERE,MFN2,HTR7,SEC31A,TAF2,RAP1A,RBBP8,SLC30A3,TBC1D22A,CHD3,SLC25A11,NFRKB,MUTYH,MPST |
| 7.977e-04 | -7.13 | ACTGCAG,MIR-17-3P | MSigDB lists | ACTGCAG,MIR-17-3P | 101 | 25 | 17758 | 2279 |
HMGA2,SPRED2,SNX27,ARID2,KHDRBS1,KCNMA1,HDAC8,FOXP1,DHX57,YTHDF2,CAMK2D,KPNA3,HIF1A,RNF111,GTF2H1,CTR9,FKBP5,CNOT6,IGF2BP1,SORCS2,BRWD3,CNOT4,FNBP1L,ZFHX2,MAML3 |
| 7.977e-04 | -7.13 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 101 | 25 | 17758 | 2279 |
ZNF292,INSIG2,PDK1,EGR1,ZNF654,SLC2A1,AKAP12,ATXN1,CAV1,NOL3,BHLHE40,FAM13A,ANGPTL4,PLIN2,DST,PTRF,KDM4B,DSC2,SRD5A3,HK2,AHNAK2,PAM,RBPJ,SAMD4A,YEATS2 |
| 7.997e-04 | -7.13 | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDM_DN | 194 | 41 | 17758 | 2279 |
SEPHS2,BCCIP,CYP24A1,MYO7A,CCDC47,GFM2,POM121,FRRS1,NOP56,PRKCH,PRKD3,DDX56,TSPAN2,SREBF2,ZSWIM7,PPCDC,CPSF3,TSPAN14,PRMT3,CAV2,TMLHE,ACSL5,FADS1,RFC4,GARS,LIMA1,PPARG,XPO5,IMPDH2,SOX4,MAK16,TARS,SMPDL3B,HERPUD1,MLLT10,ETFDH,ALG5,CTAGE5,SQLE,ADAM9,RNF130 |
| 7.997e-04 | -7.13 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_DN | 194 | 41 | 17758 | 2279 |
SEPHS2,GGT1,HMGA2,PSTPIP2,ID2,SPATS2,BZW2,FLNB,FDX1,SLC39A11,IGF2BP3,TOM1L1,CHD7,SUB1,ASNS,SUV39H2,COPS3,DSG2,IGF2BP1,VCL,ZNF518B,TRIM13,PARP2,TMEM126A,HOMER2,PTPN12,PHACTR2,PTK2,DSP,EPRS,NSF,FSCN1,KLF4,ARNTL,HK2,SLC16A1,SEMA3C,PTPN14,GCSH,RBP1,ANAPC4 |
| 8.017e-04 | -7.13 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | 188 | 40 | 17758 | 2279 |
B4GALT5,ST6GAL1,SLC2A1,C14orf159,SBF2,CHAC1,HSPA1A,NEDD4,LPIN1,DDIT4,CEP164,CHD7,NEK6,MYH3,PTGS1,PRPS1,ANTXR2,PHLDB2,FBXO17,SLC3A2,GARS,PDK1,ALDH1L2,MARCKSL1,VIM,PRDM1,ENC1,CRYBG3,HSPA1B,BATF3,IFT81,TRIB3,AHNAK,MTHFD2,GADD45A,ARL6IP5,ANXA2,NAPA,ZAK,PKIB |
| 8.042e-04 | -7.13 | regulation of cell cycle | biological process | GO:0051726 | 952 | 157 | 16441 | 2138 |
THOC5,CUL7,CUL4A,KMT2E,ATRX,PRKAB2,PLRG1,CSNK2A1,CSPP1,CCNL2,SIRT2,PRKCA,NLE1,BIRC2,MAP2K3,TOM1L1,DST,ANAPC1,NEK6,ZFHX3,ANAPC11,ANAPC10,MAD1L1,WIZ,CDK6,PRKACB,SRPK2,CDC37,PTPRK,ZBTB17,TXLNG,CDK4,HDAC8,BRCA1,SOX4,SON,DOT1L,DDX3X,SKIL,BRCA2,TRRAP,TOM1L2,GATA6,CCNT1,RAD51B,CHMP4C,ANKRD17,SLK,KHDRBS1,PIK3R4,LAMTOR3,PID1,CDC73,RNF40,PRKCE,MYC,GTF2H1,PRMT5,CAV2,TERF2,ADARB1,CRADD,SMARCD3,PSMA1,TPRA1,PLCB1,TRIM37,UBE2E1,TCF7L2,ZNF655,MYBBP1A,LEMD3,CDK9,RRAGA,SGSM3,BCCIP,CHMP2A,SART1,CYLD,BIRC6,PAFAH1B1,SMARCA4,PBX1,GBF1,SBDS,PDE3A,ASNS,C6orf89,CDK12,LSM10,HTRA2,CTC1,PRPF19,BRD4,ASUN,CCNDBP1,TTC28,NUP214,STK10,FGFR1,PES1,SMAD3,MSX2,CAMK2D,CDC16,COPS5,HIPK2,NSMCE2,ARNTL,RPS6KB1,TRIM36,HMGA2,TNIK,MINK1,XPC,TCF3,ID2,GAS6,PPP1R1C,RNASEH2B,TGFB2,GDPD5,GIGYF2,PSMF1,MAD2L2,ABL1,TRIAP1,RDX,FBXO31,MAP3K14,DMRT1,PPP1R9B,TRNP1,MSX1,FOXN3,FZD3,TEX14,TBRG4,MEN1,FOXC1,UBC,MFN2,ANXA1,OXSR1,KLHL22,GADD45A,TBX3,CUL2,FNTB,ATM,SVIL,BMP4,NR2F2,ZAK,ANAPC4,DDIT3,STK4 |
| 8.049e-04 | -7.12 | nBAF complex | cellular component | GO:0071565 | 14 | 7 | 17570 | 2233 |
SMARCA4,SMARCD3,DPF3,ARID1A,SMARCC1,ARID1B,SMARCB1 |
| 8.129e-04 | -7.11 | ACTGTGA,MIR-27A,MIR-27B | MSigDB lists | ACTGTGA,MIR-27A,MIR-27B | 448 | 81 | 17758 | 2279 |
ADAM19,DLL4,ATP6V1A,ARID2,ENAH,FAM13A,UBR5,SEMA6A,PDE3A,RPGRIP1L,ZNF827,NEK6,UBR1,PDS5B,SOCS6,RNF111,FAM184A,PPARG,ANK2,SATB2,RAD54B,DOT1L,KPNA3,SH3RF1,GREB1L,RPS6KB1,DIRAS1,NFASC,RUNX1,BMI1,TROVE2,TMCC1,AK2,FOXO1,CLK1,MAPK8IP3,NHS,MED13L,ID2,ZFP36L1,C1orf52,RPS6KA5,NEDD4,POM121,SLC39A11,SIPA1L3,EIF2S2,SLC7A11,MBD2,CACNB2,ACOT11,PRICKLE2,GLTP,NRIP1,LPCAT1,SCAF11,STAG1,LSM12,FOXN3,AGPAT4,USP42,JMJD1C,PSMA1,ST6GALNAC3,SNAP25,FAM126B,ARRDC4,SYT1,MBNL2,EVI5,USP46,IRS1,CDH24,ORC5,CSRNP1,SLCO5A1,ARHGAP12,APAF1,GPAM,PDLIM5,MAP2K4 |
| 8.155e-04 | -7.11 | protein kinase complex | cellular component | GO:1902911 | 91 | 23 | 17570 | 2233 |
BCCIP,GTF2H3,BRD4,MAP3K13,RB1CC1,PRKAB2,CDK4,KDM5A,CCNL2,TGFBR2,ERC1,IRS1,SNW1,CCNT1,PHKA1,CDK9,DNAJA3,IKBKB,GTF2H1,CDK12,CDK6,PRKAR2A,PRKACB |
| 8.180e-04 | -7.11 | SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4) | protein interactions | 6597 | 199 | 45 | 16036 | 2270 |
EP400,NCOR2,NF1,ARID2,DPF2,SIRT7,PBX1,RPS6KA5,ARID1B,NOP56,SMARCB1,CAD,CHD7,RAP1A,MYC,RELB,ZEB1,RNF2,GTF3C3,PRMT5,CARM1,DPF3,MPP6,BRD4,PPARG,SMARCAD1,SMARCD3,BRCA1,ARID1A,SETD7,ANGPTL4,POLR3A,POLR2A,SMAD3,SMARCC1,ADNP,HIF1A,COPS5,KLF4,H2AFX,NCOR1,RUNX1,RBPJ,BMI1,RFXAP |
| 8.198e-04 | -7.11 | RRAGTTGT_UNKNOWN | MSigDB lists | RRAGTTGT_UNKNOWN | 237 | 48 | 17758 | 2279 |
SNX27,BCKDK,PRPF31,CA11,OSBPL9,TMEM104,PTPRG,ZNF691,MBNL1,ARID1B,PCDH7,ZEB1,PRICKLE2,FUT11,ETV1,ZMYM2,MOSPD1,PTPRK,SOBP,MSI2,BDNF,HMBOX1,NRAS,STAG1,POLK,ZC4H2,FOXN3,ARRDC3,RDH10,TOP3A,COL4A3BP,ZDHHC14,ERC1,NR2F1,RERE,NAP1L5,MSX2,BICD1,SPAG9,SYNCRIP,KLF4,INTS9,ZNF436,CSMD3,ZNF32,BMP4,MAGI1,RAB30 |
| 8.221e-04 | -7.10 | NOC2L (NOC2-like nucleolar associated transcriptional repressor) | protein interactions | 26155 | 63 | 19 | 16036 | 2270 |
WDR36,NIFK,CUL7,DDX24,DDX18,SIRT7,NOL6,DKC1,PUM3,PES1,DDX56,ATXN7,GLYR1,CEBPZ,SHMT2,DDX31,RNF2,FBL,FTSJ3 |
| 8.260e-04 | -7.10 | SIN3A (SIN3 transcription regulator family member A) | protein interactions | 25942 | 188 | 43 | 16036 | 2270 |
NCOR2,TAF1,NFX1,ID2,CSNK2A1,SMARCA4,BHLHE40,KDM1A,SMARCB1,SKI,SNW1,S100A10,THADA,MBD2,MAD1L1,RAN,AHCYL1,PRMT5,KMT2A,MYB,SAP30,TFCP2,SMARCAD1,MEN1,SYT1,ISG15,MKX,SNCA,SMAD3,SKIL,IKZF4,TOM1L2,SMARCC1,CHD3,HIF1A,E2F4,TBL1X,NCOR1,RUNX1,RBPJ,IGBP1,PDLIM5,RBP1 |
| 8.400e-04 | -7.08 | benign | COSMIC cancer mutations | benign | 275 | 54 | 17775 | 2278 |
DCTN3,HERC2,BRAF,RBM33,BIRC6,ZCCHC8,NF1,ATRX,LPCAT2,ZNF280C,CACNA1H,SMARCA4,ZNF107,WDR26,SPATS2,PIBF1,GIGYF2,FAM8A1,CMTM3,URB1,ABCA7,CAD,PDZD2,ZEB1,CTR9,CAV2,PTPRK,SCAF11,COL17A1,NRAS,ALG6,ZNF195,TCEB3,PDE2A,KMT2C,NHSL1,ANKRD20A4,ZNF407,EXOC6,BSN,DYNC1H1,ASCC3,AHNAK,PALB2,VCAN,ZZEF1,DNAH17,MSH3,IFT140,RWDD2B,HEATR1,WDR33,ZNF598,TROVE2 |
| 8.440e-04 | -7.08 | XRCC4 (X-ray repair complementing defective repair in Chinese hamster cells 4) | protein interactions | 7518 | 36 | 13 | 16036 | 2270 |
USP7,AHNAK,LONRF2,CWC27,CHD3,APLF,LIG4,CSNK2A1,VIM,APTX,CAAP1,XRCC4,DENR |
| 8.440e-04 | -7.08 | GRWD1 (glutamate-rich WD repeat containing 1) | protein interactions | 83743 | 36 | 13 | 16036 | 2270 |
BCCIP,WDR36,DDX56,CUL4A,NOL10,DDX24,DDX18,COPS5,RBM19,POLR1E,UBC,TOP1,DOT1L |
| 8.440e-04 | -7.08 | RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 23168 | 36 | 13 | 16036 | 2270 |
UBTF,PAF1,BRD4,WDR61,ZC3H18,CTR9,CSNK2A1,ETF1,SUPT5H,SRRM2,CDC73,NEDD4,SRPK2 |
| 8.449e-04 | -7.08 | positive regulation of metabolic process | biological process | GO:0009893 | 3495 | 511 | 16441 | 2138 |
ARHGAP26,ZNF292,THOC5,DCP1B,SBF2,HLTF,CCNL2,PRKCA,ABHD6,LPAR3,GABPB2,LPIN1,AMBRA1,NOS1AP,SKI,GIPR,TOM1L1,SREBF2,ZFHX3,S100A10,PMAIP1,RABGAP1L,WIZ,RNF111,ZNF148,FNIP2,MEIS3,FXN,CDK6,TBC1D8,DDN,HMBOX1,NRAS,NR6A1,GNL3,EYA3,NFIA,TCEB3,CUX1,AKAP12,C5AR1,SUPT20H,DCUN1D5,DENND4A,SLC50A1,STOML2,DDX3X,DDAH2,BRCA2,SUPT4H1,CCNT1,ARL6IP5,FIS1,DIRAS1,RUNX1,TPM1,NRP1,BMI1,RFXAP,P2RY11,MEF2C,BANP,HERC2,EPM2AIP1,IFT57,DROSHA,EGR1,CDC42EP2,JUP,SLK,KHDRBS1,TRIO,SIRT7,OPHN1,PIK3R4,PID1,RSF1,TGFBR2,PDCD5,CDC73,ABCA7,CHN1,RBM20,PRKCE,FKBP1A,UBE3A,ENTPD5,ASAP1,APLF,MYC,MED24,ANP32B,MAP3K12,LPCAT1,CAV2,PABPC1,TERF2,MYB,HMGCR,PEA15,GTF2H3,BDNF,SYNGAP1,WDR61,STAG1,RREB1,RB1CC1,PRDM16,ARID5B,RAPGEF4,RAP1GAP2,RAP1B,RYR2,SMARCD3,ARID1A,NELFA,ARRDC4,EVI5,PLCB1,CPT1A,TRIM37,ONECUT2,ABCF1,ARIH2,IRS1,CAT,TASP1,KIDINS220,NSF,HIF1A,CDK9,SPEN,NCOR1,IQSEC2,ARHGAP10,SMYD3,SGSM3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,MYH9,AGAP6,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SLX4,SHC1,ACD,TBC1D22A,WAC,LPIN2,DTNBP1,MMP14,SSBP1,KMT2A,DENND1A,PERP,CASP8AP2,BRD4,KMT2D,ARHGEF10,PREX1,DLG4,SATB2,MED16,MEF2D,SETD7,TBC1D16,STK10,ERC1,SERP1,FGFR1,SNCA,VDR,TAF2,FBXL5,CAMK2D,ARHGAP21,CDC16,SMARCC1,NSMCE2,DNAJA3,PEMT,HIPK2,H2AFX,RPS6KB1,ANXA2,BRCC3,TBXA2R,XRCC4,MID1,HMGA2,SERINC5,INSIG2,BRAF,TCF3,ID2,GAS6,MON2,TRIM22,TGFB2,RPS6KA5,FOXO3,PSMF1,MAD2L2,NEDD4,SFR1,TADA3,ABL1,SNW1,NPRL2,RGS17,ACAP3,TRIAP1,RAPGEFL1,ARHGAP1,RDX,YBX3,LARP4B,ERRFI1,MAP3K14,PLEKHG4,SAMD4A,SOX6,SPTAN1,MBTPS2,SLC40A1,FGF9,PXN,APEX1,WDFY3,PTK2,IL6R,UBE2K,GUF1,KLF6,FOXC1,UBC,POLR2A,ANXA1,OXSR1,TRIB3,NSD1,ARID3B,HERC1,APAF1,PSAP,BMP4,PGAM5,IGBP1,UQCC1,RABEP1,DOCK6,ANAPC4,DDIT3,KAT6A,STK4,TRIM16,AAMDC,GPBP1L1,ATRX,NF1,KMT2E,PPARGC1B,PTPRA,RCHY1,CSNK2A1,SIRT2,FAM13A,GIT2,BIRC2,HNRNPLL,MAP2K3,SMARCB1,ABL2,ANAPC1,RAP1A,PHF5A,ARHGAP18,DHX33,ANAPC11,ANAPC10,RELB,ZEB1,RAN,PCOLCE2,ETV1,PRKACB,TRIM14,SRPK2,ZBTB17,DEAF1,TNK2,TRIM13,RBCK1,ATF4,GCNT2,PPARG,ANK2,CDK4,ARRDC3,HSPA5,GMFB,SUMO3,BRCA1,CAV1,SOX4,SERGEF,MLLT10,PAF1,DYRK1B,UBTF,HPRT1,ZNF622,TCF7L1,INSIG1,GATA6,TP53BP1,DNAJC1,E2F4,PER1,MKL2,SOCS4,TNFRSF1A,CTAGE5,SGSM2,ADAM9,CLU,DLX2,ZC3H8,UQCC2,MTCH1,FN1,FOXO1,TAF1,PAX2,NKD2,MAPK8IP3,LAMTOR3,SMAD7,BARX2,TRIM15,ZIC2,RLF,ARID1B,RHBDD1,NAMPT,RNF40,ELL,SUB1,MLX,SIPA1L3,CEP290,NDRG4,BUD31,GTF2H1,VAPB,CTR9,ICE2,WNT16,NRIP1,LRSAM1,NT5E,CAMKK2,CRADD,PAXBP1,UTP15,WWC1,OBSCN,PSMA1,MEX3B,PRDM1,EIF2A,SUPT5H,AGAP1,HERPUD1,UBE2E1,TCF7L2,NR2F1,TBC1D2,ATXN7,SPAG9,IRAK2,PPP1R12B,ARHGAP12,ZFP90,TBL1X,PRKAR2A,TESC,TCF12,DLL4,ID1,ASH1L,CEMIP,NTSR1,SMARCA4,PBX1,RIPK1,DENND3,PIBF1,PELP1,GBF1,PLXNB1,KDM1A,RRN3,NRF1,BRE,JAG1,CAMTA2,NVL,GRIN2C,DNAJB6,IKBKB,MET,SPIDR,CASP10,HTRA2,CTC1,MOSPD1,PRPF19,MAML3,KAT8,ARHGAP17,DDX41,RAB7A,C1QTNF1,GRHL3,ATXN1,VIM,TOR1AIP2,AKAP13,EDEM2,DKC1,ZC3H12A,SMAD3,IKZF4,ADNP,SIX5,COPS5,KLF4,ARNTL,CEBPZ,ATG7,DUSP19,PUS1,SCARB1,HEATR1,EIF2B3,PKIB,DNAJC2,TNIK,MINK1,SH2D3A,SUPT6H,MAP3K13,CAMK1,AGO2,DBF4,ATF7IP,PIP4K2A,BMP6,IQGAP2,PTPN2,PRKCH,TMEM161A,HAS3,CD44,UTS2,DMRT1,PKNOX1,RPS6KB2,KDM6B,ARNTL2,DNMBP,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,ASAP3,RAP1GDS1,ARHGEF12,RANGAP1,ARHGAP32,MEN1,SYMPK,PIK3CB,RERE,MKX,HSPA1B,SERINC1,GADD45A,TAF4,TBX3,CSRNP1,MSH3,BCAS3,FNTB,NCBP2,MYRF,RBPJ,TAF12,NFKBIB,NR2F2,ZAK,MMP16,ARHGAP27,HRH1 |
| 8.491e-04 | -7.07 | MITOCHONDRIAL_MEMBRANE | MSigDB lists | MITOCHONDRIAL_MEMBRANE | 85 | 22 | 17758 | 2279 |
TIMM8B,BCS1L,MCL1,OPA1,RHOT2,TIMM10,NDUFS7,MFN2,ATP5D,TAMM41,NDUFV1,ATP5G2,TIMM17A,PMPCA,MPV17,SURF1,SLC25A11,FIS1,NDUFA6,TOMM34,SLC25A1,TIMM50 |
| 8.498e-04 | -7.07 | spleen | COSMIC cancer mutations | spleen | 423 | 77 | 17775 | 2278 |
ARHGAP26,AMOTL1,CYLD,ACTG1,CELSR3,KIF5A,FANCD2,TRPM6,CACNA1H,SMARCA4,ZNF107,UBR5,DDX60L,YLPM1,GLYR1,IKBKB,WAC,KIAA0922,MTHFD2L,PRKACB,MAML3,PTPRK,ACSL5,FLNC,PMS1,DTNB,EIF4E3,NRAS,KMT2D,ANK2,GRHL3,KMT2C,SLC9A5,CRYBG3,LSG1,KIF16B,TRRAP,ELP2,RLTPR,CSMD3,ABCC3,TRAF3,DISP1,PTPN14,TNIK,BRAF,XPC,DPF2,CENPB,MAPK8IP3,SOGA1,ARID1B,HAS3,RAPGEFL1,SYNJ2,ZCCHC7,TSHZ1,KLRD1,DDX28,RREB1,STAG1,FZD3,OBSCN,TBRG4,ZNFX1,PHACTR2,ARID1A,PRDM1,TRIM37,SYMPK,CDH24,LRP1B,SERINC1,HERC1,FAT1,SPEN,ATM |
| 8.505e-04 | -7.07 | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3677 | 529 | 17775 | 2278 |
ARHGAP26,CDCP1,ACTG1,CNTNAP3,CACNA1H,HLTF,HMOX2,NOS1AP,SKI,ZNF37A,TOM1L1,PCDH7,PDZD2,ZFHX3,SYN2,C12orf76,AP1M1,FNIP2,KDM5C,CDK6,NRAS,PTPRM,EXOC6B,MSRB3,C5AR1,AKAP12,SHISA5,C10orf76,RBM28,TMSB4X,DDX3X,AHNAK,TMEM139,SYNGR2,RIOK1,RUNX1,RBP1,P2RY11,CARS,HERC2,EP400,TMEM63C,CLDN15,KHDRBS1,TRIO,NHS,BTBD9,SLC1A1,RSPRY1,EIF2S2,DHX37,CCDC88C,AGL,FMNL2,ANGPT2,MYB,NOM1,LRRC20,IFRD1,COL17A1,WDR61,MYO10,ARID5B,RYR2,SMARCD3,EVI5,MBNL2,ONECUT2,DYNC1H1,LRP1B,EHMT2,FGFBP1,LEMD3,MB21D2,ARHGAP10,COG5,RAB11FIP4,ATP6V1A,DDR2,CD99L2,MYH9,AGAP6,SAFB2,MCM9,RPGRIP1L,ESAM,ABCA12,FMNL1,MSH4,MGLL,DENND1A,LYST,PMS1,KMT2D,ARHGEF10,DSP,FGFR1,TAF2,ARHGAP21,HIPK2,METTL6,WDR7,LAMA5,CEP170,MORC2,SESTD1,SF3A3,TGFB2,PSMF1,TADA3,PVRL3,UNC13A,SAMD4A,SOX6,C21orf58,ERICH1,ZC3H18,NXN,CASC1,UBC,RARS,SRCAP,NSD1,BAZ2B,PTPN4,BMP4,DOCK6,KDM4C,CYP24A1,RBM33,SLC25A21,FAM13A,TMEM132A,NLE1,GIT2,BIRC2,PHF5A,DHX33,TRMU,PPCDC,ETV1,PTPRK,DSC3,DBN1,FMNL3,ATF4,ABCC4,MIOS,BAZ2A,SKIV2L2,KATNAL1,MED27,LAMA2,BRCA1,CXADR,PEX1,TCF7L1,TNFRSF1A,SGSM2,PRPF4,USP15,CTU2,AOC3,CLK1,NKD2,LAMTOR3,ZIC2,ZFP36L1,ARID1B,DNAH1,SPIRE1,ABCA5,PPIL2,NDRG4,GMDS,PNPLA3,LRSAM1,TRAPPC9,CAMKK2,USP49,OBSCN,MEX3B,MAPK1IP1L,VAC14,GRIK4,ITPRIPL1,DNAH17,TBPL1,ZNF430,CASS4,TESC,KCTD7,USP7,LPCAT2,GPR143,RIPK1,LPCAT3,SSBP2,PPP1R9A,PLXNB1,CAD,ZNF608,CCDC40,ZFP37,CORO1A,PRPF19,TMEM200A,SKIV2L,AKAP8L,NARS,KIRREL2,C1QTNF1,AKAP13,EIF3H,ZNF251,BTBD11,SMAD3,ZNF333,ABHD3,ITGA2,ATG7,PRRT3,NFASC,EIF2B3,PARD3,ZNF507,UNC13D,FAM46B,FOXP1,ZNF594,IQGAP2,FAM50A,GREB1,CPNE7,C12orf4,ADAMTSL3,LRRIQ1,MON1A,PEAR1,RAP1GDS1,GPNMB,TMEM175,TPD52L2,SAMD5,SRBD1,DSC2,TAF4,SET,GLG1,NR2F2,ITGB4,KIF1B,GCSH,ZNF292,CGN,MYCBP2,ENAH,NBEAL1,PRKCA,UBR5,MGA,LPIN1,EXOC1,RPS16,VPS52,CHD2,CSGALNACT2,TBC1D8,DDN,SLC38A6,NR6A1,ALDH1L2,NOL8,VSNL1,DENND4A,SON,OSBPL1A,SPOP,GNAI1,LUC7L3,DNAH2,SEMA3C,NRP1,SPOCK3,ZNF598,PTPN14,WDR75,CELSR1,EGR1,PRPF31,ANKRD17,TATDN3,OPHN1,DLGAP4,GTF2IRD1,DPM3,PDCD5,ANXA10,TECTA,SLC7A11,ZNF586,ASAP1,SCAF1,MYC,SIK3,RREB1,PRIM2,PCCA,POLA1,AOC2,RAPGEF4,KIAA0586,ARID1A,EHBP1,PLCB1,ATP9B,SPEN,VCAN,NCOR1,CNDP2,MAP2K4,CPT1C,RTTN,SYT17,AMOTL1,BIRC6,HFM1,CORO6,PTPRG,PDE3A,IGSF1,FLNB,NOP56,PHC2,TERF2IP,CHD7,DECR1,NBEA,CDK12,ZCCHC14,BRD4,WDPCP,SATB2,GALK2,PNN,MARCH6,TBC1D16,DHX57,VDR,CAMK2D,DNTTIP1,IFT140,ALKBH1,TRAF3,MDN1,MID1,FGFBP3,NOSTRIN,BRAF,C10orf2,TCF3,NFX1,KIF5C,RCAN1,IKBKAP,INPP1,FAM8A1,ABL1,LRP2BP,NISCH,NLGN3,MBTPS2,FAM120B,TSHZ1,FER1L5,WDFY3,AGPAT4,KCNMA1,TBRG4,BMS1,PACS1,SLC23A2,SVIL,ATM,MYOM2,APAF1,DDIT3,LRRC41,IMMP2L,PHF3,NF1,ATRX,KIF5A,TRPM6,FANCD2,PLOD1,BCOR,DST,ZNF804A,RTN1,THADA,YLPM1,JAZF1,ZNHIT6,GPR87,MYH3,ZEB1,POLR3B,B3GNTL1,SLC27A5,LONP1,CARM1,ZBTB17,LAMA4,SKAP2,SLC38A1,GPCPD1,COTL1,PITPNB,KMT2C,CDHR3,GEMIN5,TMEM132B,CCDC3,EPN2,DNAJC1,FAM114A2,RLTPR,CSMD3,ASB3,ABCC3,CLU,EME1,GALNT10,MTCH1,TNRC6A,CHST11,FN1,ZCCHC8,TAF1,RHOBTB1,DPF2,EVPL,QSER1,PHGDH,ETFB,CEP164,SIPA1L3,MCAM,ISPD,SEMA3D,CCDC112,ZNF629,VOPP1,MSI2,ELOVL6,XPO5,CORIN,SYT1,HERPUD1,EXOC6,UBAP2,FAT1,HK2,EXOC4,KIAA1328,TBCK,PDE9A,N4BP2L2,DMXL2,TMEM177,ARSJ,DHX35,GBF1,RAET1E,ZC3H13,MPHOSPH10,CAMTA2,PPFIBP1,SNTG2,MET,C6orf89,PHLDB2,PRAME,ANTXR2,FAM172A,COL5A2,TFCP2,ATXN1,NLN,TOR1AIP2,UBR4,WARS,HYAL3,SRFBP1,SMG1,TNIK,SULT1C2,PDE4B,CLSTN2,SEMA3E,CCDC7,HDDC2,PRKCH,GART,SEC24C,STC2,DSG2,LDLRAD3,TTC17,MICAL3,RPS6KB2,SLC6A16,CRIM1,TEAD1,KDM5A,MARS,ARHGAP32,PDE2A,NAALADL2,TARS,WDR35,AGTPBP1,NCBP2,MBD6,PREPL,ZAK,MMP16,HRH1 |
| 8.505e-04 | -7.07 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3677 | 529 | 17775 | 2278 |
ARHGAP26,CDCP1,ACTG1,CNTNAP3,CACNA1H,HLTF,HMOX2,NOS1AP,SKI,ZNF37A,TOM1L1,PCDH7,PDZD2,ZFHX3,SYN2,C12orf76,AP1M1,FNIP2,KDM5C,CDK6,NRAS,PTPRM,EXOC6B,MSRB3,C5AR1,AKAP12,SHISA5,C10orf76,RBM28,TMSB4X,DDX3X,AHNAK,TMEM139,SYNGR2,RIOK1,RUNX1,RBP1,P2RY11,CARS,HERC2,EP400,TMEM63C,CLDN15,KHDRBS1,TRIO,NHS,BTBD9,SLC1A1,RSPRY1,EIF2S2,DHX37,CCDC88C,AGL,FMNL2,ANGPT2,MYB,NOM1,LRRC20,IFRD1,COL17A1,WDR61,MYO10,ARID5B,RYR2,SMARCD3,EVI5,MBNL2,ONECUT2,DYNC1H1,LRP1B,EHMT2,FGFBP1,LEMD3,MB21D2,ARHGAP10,COG5,RAB11FIP4,ATP6V1A,DDR2,CD99L2,MYH9,AGAP6,SAFB2,MCM9,RPGRIP1L,ESAM,ABCA12,FMNL1,MSH4,MGLL,DENND1A,LYST,PMS1,KMT2D,ARHGEF10,DSP,FGFR1,TAF2,ARHGAP21,HIPK2,METTL6,WDR7,LAMA5,CEP170,MORC2,SESTD1,SF3A3,TGFB2,PSMF1,TADA3,PVRL3,UNC13A,SAMD4A,SOX6,C21orf58,ERICH1,ZC3H18,NXN,CASC1,UBC,RARS,SRCAP,NSD1,BAZ2B,PTPN4,BMP4,DOCK6,KDM4C,CYP24A1,RBM33,SLC25A21,FAM13A,TMEM132A,NLE1,GIT2,BIRC2,PHF5A,DHX33,TRMU,PPCDC,ETV1,PTPRK,DSC3,DBN1,FMNL3,ATF4,ABCC4,MIOS,BAZ2A,SKIV2L2,KATNAL1,MED27,LAMA2,BRCA1,CXADR,PEX1,TCF7L1,TNFRSF1A,SGSM2,PRPF4,USP15,CTU2,AOC3,CLK1,NKD2,LAMTOR3,ZIC2,ZFP36L1,ARID1B,DNAH1,SPIRE1,ABCA5,PPIL2,NDRG4,GMDS,PNPLA3,LRSAM1,TRAPPC9,CAMKK2,USP49,OBSCN,MEX3B,MAPK1IP1L,VAC14,GRIK4,ITPRIPL1,DNAH17,TBPL1,ZNF430,CASS4,TESC,KCTD7,USP7,LPCAT2,GPR143,RIPK1,LPCAT3,SSBP2,PPP1R9A,PLXNB1,CAD,ZNF608,CCDC40,ZFP37,CORO1A,PRPF19,TMEM200A,SKIV2L,AKAP8L,NARS,KIRREL2,C1QTNF1,AKAP13,EIF3H,ZNF251,BTBD11,SMAD3,ZNF333,ABHD3,ITGA2,ATG7,PRRT3,NFASC,EIF2B3,PARD3,ZNF507,UNC13D,FAM46B,FOXP1,ZNF594,IQGAP2,FAM50A,GREB1,CPNE7,C12orf4,ADAMTSL3,LRRIQ1,MON1A,PEAR1,RAP1GDS1,GPNMB,TMEM175,TPD52L2,SAMD5,SRBD1,DSC2,TAF4,SET,GLG1,NR2F2,ITGB4,KIF1B,GCSH,ZNF292,CGN,MYCBP2,ENAH,NBEAL1,PRKCA,UBR5,MGA,LPIN1,EXOC1,RPS16,VPS52,CHD2,CSGALNACT2,TBC1D8,DDN,SLC38A6,NR6A1,ALDH1L2,NOL8,VSNL1,DENND4A,SON,OSBPL1A,SPOP,GNAI1,LUC7L3,DNAH2,SEMA3C,NRP1,SPOCK3,ZNF598,PTPN14,WDR75,CELSR1,EGR1,PRPF31,ANKRD17,TATDN3,OPHN1,DLGAP4,GTF2IRD1,DPM3,PDCD5,ANXA10,TECTA,SLC7A11,ZNF586,ASAP1,SCAF1,MYC,SIK3,RREB1,PRIM2,PCCA,POLA1,AOC2,RAPGEF4,KIAA0586,ARID1A,EHBP1,PLCB1,ATP9B,SPEN,VCAN,NCOR1,CNDP2,MAP2K4,CPT1C,RTTN,SYT17,AMOTL1,BIRC6,HFM1,CORO6,PTPRG,PDE3A,IGSF1,FLNB,NOP56,PHC2,TERF2IP,CHD7,DECR1,NBEA,CDK12,ZCCHC14,BRD4,WDPCP,SATB2,GALK2,PNN,MARCH6,TBC1D16,DHX57,VDR,CAMK2D,DNTTIP1,IFT140,ALKBH1,TRAF3,MDN1,MID1,FGFBP3,NOSTRIN,BRAF,C10orf2,TCF3,NFX1,KIF5C,RCAN1,IKBKAP,INPP1,FAM8A1,ABL1,LRP2BP,NISCH,NLGN3,MBTPS2,FAM120B,TSHZ1,FER1L5,WDFY3,AGPAT4,KCNMA1,TBRG4,BMS1,PACS1,SLC23A2,SVIL,ATM,MYOM2,APAF1,DDIT3,LRRC41,IMMP2L,PHF3,NF1,ATRX,KIF5A,TRPM6,FANCD2,PLOD1,BCOR,DST,ZNF804A,RTN1,THADA,YLPM1,JAZF1,ZNHIT6,GPR87,MYH3,ZEB1,POLR3B,B3GNTL1,SLC27A5,LONP1,CARM1,ZBTB17,LAMA4,SKAP2,SLC38A1,GPCPD1,COTL1,PITPNB,KMT2C,CDHR3,GEMIN5,TMEM132B,CCDC3,EPN2,DNAJC1,FAM114A2,RLTPR,CSMD3,ASB3,ABCC3,CLU,EME1,GALNT10,MTCH1,TNRC6A,CHST11,FN1,ZCCHC8,TAF1,RHOBTB1,DPF2,EVPL,QSER1,PHGDH,ETFB,CEP164,SIPA1L3,MCAM,ISPD,SEMA3D,CCDC112,ZNF629,VOPP1,MSI2,ELOVL6,XPO5,CORIN,SYT1,HERPUD1,EXOC6,UBAP2,FAT1,HK2,EXOC4,KIAA1328,TBCK,PDE9A,N4BP2L2,DMXL2,TMEM177,ARSJ,DHX35,GBF1,RAET1E,ZC3H13,MPHOSPH10,CAMTA2,PPFIBP1,SNTG2,MET,C6orf89,PHLDB2,PRAME,ANTXR2,FAM172A,COL5A2,TFCP2,ATXN1,NLN,TOR1AIP2,UBR4,WARS,HYAL3,SRFBP1,SMG1,TNIK,SULT1C2,PDE4B,CLSTN2,SEMA3E,CCDC7,HDDC2,PRKCH,GART,SEC24C,STC2,DSG2,LDLRAD3,TTC17,MICAL3,RPS6KB2,SLC6A16,CRIM1,TEAD1,KDM5A,MARS,ARHGAP32,PDE2A,NAALADL2,TARS,WDR35,AGTPBP1,NCBP2,MBD6,PREPL,ZAK,MMP16,HRH1 |
| 8.515e-04 | -7.07 | SANT/Myb | interpro domains | IPR001005 | 49 | 15 | 18293 | 2341 |
CHD7,DNAJC2,NCOR2,EP400,SMARCC1,GON4L,TRERF1,DNAJC1,NCOR1,DMTF1,SNAPC4,RERE,CRAMP1,MYB,TERF2 |
| 8.532e-04 | -7.07 | V$ETF_Q6 | MSigDB lists | V$ETF_Q6 | 107 | 26 | 17758 | 2279 |
ZBTB17,ASH1L,PRDM16,NFIA,POU2F1,ARID1A,STAM,UBR4,CDC73,KDM1A,RERE,MFN2,YTHDF2,TSPAN2,SUV39H2,UCHL5,CUL2,WAC,ZEB1,RNF2,CMPK1,BMI1,TROVE2,PRKACB,CSGALNACT2,ATXN7L2 |
| 8.572e-04 | -7.06 | GGCAGCT,MIR-22 | MSigDB lists | GGCAGCT,MIR-22 | 219 | 45 | 17758 | 2279 |
DNM3,DPF2,SLC2A1,OLA1,ARFIP2,NECAP1,CCDC47,FOXP1,EDC3,CHD7,ANKRD13A,THADA,COPS7B,RAPGEFL1,CLDND1,LDLRAD3,AMOT,MAP3K12,YARS,FBXL19,ZCCHC14,CHD9,BRD4,LAMC1,WDFY3,FOXN3,LGALS1,PCNXL2,RSBN1,ARHGEF12,SATB2,USP46,SLC9A5,DHX57,MAT2A,BATF3,CTIF,MTHFD2,IKZF4,KIAA0355,ARID3B,PURB,DPP4,BRSK2,LPP |
| 8.578e-04 | -7.06 | KOYAMA_SEMA3B_TARGETS_DN | MSigDB lists | KOYAMA_SEMA3B_TARGETS_DN | 377 | 70 | 17758 | 2279 |
SLC37A3,CGN,NDUFA5,ASH1L,BTBD2,CSPP1,SLC6A8,UBR5,HSPA1A,CHD7,DECR1,JAG1,S100A10,TBC1D22A,DNAJB6,XRCC2,SRPK2,SOBP,ZCCHC14,NRAS,GON4L,ANKRD33B,CAMSAP2,CAV1,ZDHHC14,FLVCR1,CCDC28B,CXADR,TCF7L1,INSIG1,METTL6,LUC7L3,CCDC146,SEMA3C,PRRT3,FKBP5,TPM1,TMEM158,LPP,SLC12A7,BRAF,FN1,CELSR1,SCAMP3,NKD2,ID2,BTBD9,QSER1,TGFB2,FOXP1,CDC73,FKBP1A,CCDC167,MAP3K14,CAV2,FAM120B,MYO10,ARID5B,SMARCD3,RSBN1,KLF6,HSPA1B,DKK1,PMEPA1,ZZEF1,TBX3,EXOC4,SVIL,POLR1C,GPATCH4 |
| 8.595e-04 | -7.06 | OTUD5 (OTU deubiquitinase 5) | protein interactions | 55593 | 20 | 9 | 16036 | 2270 |
LONRF2,SET,TRAF3,VARS,USP11,IGBP1,PDCD5,UBC,ARPC3 |
| 8.614e-04 | -7.06 | Purine metabolism | REACTOME pathways | R-HSA-73847 | 33 | 12 | 8202 | 1117 |
CAT,HPRT1,AMPD3,GART,PPAT,ATIC,ADSL,APRT,NT5C,IMPDH2,ADK,NT5E |
| 8.660e-04 | -7.05 | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | 576 | 100 | 17775 | 2278 |
CDCP1,MVK,BIRC6,ATRX,PDK4,CSNK2A1,PRKCA,GBF1,MAP2K3,RPP30,ZNF804A,ABL2,ZNF827,FMNL1,RPS6KL1,GSTA4,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,FLNC,TNK2,NRAS,PDK1,CDK4,CUX1,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,TJAP1,BRCA2,HIPK2,CSMD3,RPS6KB1,TROVE2,PTPN14,HMGA2,SEPHS2,TNIK,AK2,BRAF,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,CCDC7,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,IQGAP2,PRKCH,ABL1,SACS,PI4KB,GTF2H1,ALDH18A1,MAP3K12,TOMM34,RPS6KB2,CAMKK2,RB1CC1,MON1A,CRIM1,PRDM16,ARID5B,ARID1A,PALLD,C8orf33,PIK3CB,CENPP,DAGLA,NSD1,SRCAP,TRIB3,LRP1B,FAM135A,DAGLB,HERC1,SPEN,HK2,ATM,CNDP2,PDLIM5,RPS6KC1,MAP2K4,PRKAR2A,DDIT3 |
| 8.677e-04 | -7.05 | MORF_BUB3 | MSigDB lists | MORF_BUB3 | 275 | 54 | 17758 | 2279 |
SRM,AK2,MCM6,SCAMP3,PRPF31,KHDRBS1,RSL1D1,XPO7,HDDC2,POM121,PABPC4,NDUFB3,CAD,NDUFV1,EIF2S2,SREBF2,MCM5,SEC24C,UBAP2L,MRPS27,TNPO3,SSBP1,RAN,POLE3,ANP32B,FBL,YARS,GNG5,HNRNPM,SERBP1,NUDC,RFC4,IFRD1,GARS,SKIV2L2,IDH3G,R3HDM1,RANGAP1,IMPDH2,MCM2,DKC1,SERP1,DDX49,TARS,CHAF1A,ATP5D,EPRS,HNRNPR,COPS5,SET,ACP1,GPN1,NCBP2,NDUFS5 |
| 8.721e-04 | -7.04 | CTCAGGG,MIR-125B,MIR-125A | MSigDB lists | CTCAGGG,MIR-125B,MIR-125A | 313 | 60 | 17758 | 2279 |
KLHL24,NCOR2,CGN,ZNF76,DLL4,LIN28B,UBN1,PAFAH1B1,ST6GAL1,DPF2,SIRT7,OSBPL9,CSNK2A1,PCSK7,ZNF691,ABHD6,MTUS1,PHC2,RNF40,SYN2,ATP5G2,TRIAP1,COPS7B,RAPGEFL1,LYPLA2,DIS3L2,ANTXR2,FBXW4,BAZ2A,ZFYVE1,PPAT,ELOVL6,ATXN1,SATB2,MCL1,PRDM1,TRAPPC6B,RHOT2,NEU1,WARS,TAF9B,BSN,VDR,SLC7A1,CACNB1,IKZF4,ARID3B,ZNF236,SET,ABHD3,SOCS4,HIC2,ADAM9,DIRAS1,SCARB1,IQSEC2,GGT7,FAM118A,ZFHX2,SMG1 |
| 8.765e-04 | -7.04 | NEGATIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS | 207 | 43 | 17758 | 2279 |
ZNF254,ID1,ZHX3,RBFOX2,KHDRBS1,NFX1,ID2,ATF7IP,SIRT2,BCOR,RSF1,TERF2IP,SNW1,VPS72,JAZF1,TIMELESS,ZEB1,ZNF148,NRIP1,TERF2,KAT8,KDM5B,NR6A1,FOXN3,ARID5B,CUX1,ATXN1,POU2F1,HDAC8,PRDM1,BRCA1,SUPT5H,MEN1,SMAD3,VDR,NSD1,SUPT4H1,KLF4,PER1,SET,TBX3,RBPJ,KAT6A |
| 8.768e-04 | -7.04 | YANG_BREAST_CANCER_ESR1_LASER_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_LASER_DN | 49 | 15 | 17758 | 2279 |
ARNTL2,PRKD3,IFRD1,MPP6,AK2,BICD1,SYNCRIP,DSC2,FSCN1,ST3GAL6,ODC1,FOXC1,SERBP1,TCF7L2,ANXA1 |
| 8.832e-04 | -7.03 | ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog) | protein interactions | 51575 | 13 | 7 | 16036 | 2270 |
ADAM19,RNF2,MPHOSPH10,DDX18,NOP58,SIRT7,PUM3 |
| 8.835e-04 | -7.03 | striated_muscle | COSMIC cancer mutations | striated_muscle | 4392 | 624 | 17775 | 2278 |
ARHGAP26,GGT1,DCP1B,CACNA1H,SBF2,CSPP1,CCNL2,SYNJ1,SKI,C1orf159,PDZD2,ZFHX3,MAD1L1,PDS5B,HRG,AVEN,SRRM2,CCDC57,NRAS,KLHL23,PTPRM,NFIA,KIF15,RFX2,ABCC2,SLC50A1,AHNAK,BRCA2,RUNX1,HERC2,EP400,TMEM63C,SIRT7,PIK3R4,PDCD7,PARN,CDC73,PITPNM1,SLC1A1,ABCA7,RSPRY1,SH2B3,RBM20,DDX56,KIAA1671,INTS7,ANP32B,GEMIN4,NOC3L,CCDC88C,COQ3,ZNF518B,AGL,FMNL2,NOM1,HMGCR,COL17A1,KCNQ3,MYO10,RB1CC1,PRDM16,ARID5B,EPS15L1,RYR2,SMARCD3,MAP7D1,CPT1A,TRIM37,EVI5,NCDN,IRS1,DYNC1H1,VPS13C,LRP1B,GTF2A1,GSTO2,PDLIM1,ZNF160,WDR33,PDLIM5,ZNF516,MYH9,AGAP6,ISG20L2,TUBB6,RPGRIP1L,SETD5,FMNL1,WAC,CLCN6,MSH4,PEG10,DENND1A,GARS,KMT2D,FAM111B,EIF3J,ARHGEF10,GSTCD,TTC28,DSP,VPS53,MAT2A,FGFR1,ZFAND3,PES1,ASTN2,HIPK2,METTL6,POLR3E,PAM,LAMA5,METTL2B,YEATS2,CATSPERG,BAG1,MAPT,TRIM36,MORC2,ZNF786,XPC,ATG2B,BHLHE40,PSMF1,TAF3,UNC13A,ACOT11,ARHGAP1,SOX6,HNRNPM,SPTAN1,DIS3L2,DDHD1,C21orf58,ERICH1,POLK,ZC3H18,LDHA,ZNF467,CCDC150,ETFDH,RARS,SRCAP,NSD1,PXDN,HERC1,PTPN4,AEN,GPAM,SORCS2,DOCK6,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,PPARGC1B,MFGE8,RNF43,FAM13A,SEC16A,SCAF8,MAP2K3,FRRS1,TRMU,XRCC2,ANKRD11,MPST,VPS13B,METTL1,FLNC,DSC3,FMNL3,CHD9,ABCC4,MIOS,BAZ2A,SKIV2L2,PPARG,ANK2,LAMA2,BRCA1,KCNH2,CRYBG3,PEX1,BSN,DYRK1B,GLS,TCF7L1,MSRA,TP53BP1,PER1,TNFRSF1A,ADAM9,CTU2,ITFG1,PRSS3,SMAD7,MEX3A,HES6,RLF,ARID1B,DNAH1,DOPEY1,CEP290,PDE10A,VAPB,SYNJ2,CWF19L2,LRSAM1,SNX29,NT5E,SETD2,HAUS6,BCS1L,OBSCN,CYB5B,ACOXL,NR2F1,TCF7L2,ATXN7,FAM135A,SPAG9,PALB2,SNAP23,DNAH17,CASS4,BCCIP,ID1,PAPD4,UPK3B,ARID2,ZNF83,LPCAT3,DENND3,RADIL,ZNF121,DDX60L,PELP1,PLXNB1,FDX1,KDM1A,ZNF608,JAG1,NUP133,GRIN2C,UBR1,ARMC5,DNAJB6,CCDC40,HIBCH,ANO8,MYH15,CASP10,CTC1,TMEM200A,KDM3B,SEC24A,SOBP,WDR36,PCGF3,SSFA2,GLTSCR2,THSD4,ANKRD33B,RAB7A,MANBAL,VIM,AKAP13,NHSL1,NUP214,BTBD11,ATP5D,EXO1,SLC30A3,LMBR1L,SIX5,ZNF333,CLEC16A,ITGA2,ATG7,TSSC1,INTS9,PRRT3,NFASC,MUTYH,PARD3,ATXN7L2,ZNF507,UNC13D,C14orf159,MAP1S,RBM19,FOXP1,RMI1,POGZ,BZW2,ZNF594,ANKRD54,IQGAP2,PTPN2,FAM50A,PRICKLE2,DDX31,POLR1B,CPNE7,FAM71E1,ADAMTSL3,LRRIQ1,C22orf34,ARHGEF12,C11orf49,RHOT2,ARMC3,SMPDL3B,NEU1,ZRANB3,TPD52L2,DSC2,TAF4,GLG1,BCAS3,USP20,RBPJ,NR2F2,C6orf223,ZNF292,CGN,MYCBP2,NBEAL1,RAC3,AARS,UBR5,LPIN1,GIPR,RNF111,CEP135,CSGALNACT2,ZNF646,TBC1D8,ACADS,SLC38A6,CUX1,TCEB3,EFHC1,ZDHHC14,SON,DENND4A,PLCXD2,OSBPL1A,TRRAP,VPS13D,DNAH2,WDR66,TXN2,BLMH,ZNF598,SPOCK3,PTPN14,WDR75,IFT57,JUP,CELSR1,LARS2,ZHX3,DLGAP4,CCDC47,PRPF39,CD226,MTUS1,TECTA,FAM192A,NAV1,HR,TSPAN2,SCAF1,COPS3,VWDE,PIGG,GTF3C3,CNOT4,FDFT1,SIK3,RREB1,POLA1,KIAA0586,TTYH2,PTPN12,ARID1A,MTR,ANGPTL4,ARIH2,LYRM7,ATP9B,ZNF425,DAGLA,ASCC3,PMEPA1,ZZEF1,SRP68,D2HGDH,DPEP1,CNDP2,MAP2K4,ZFHX2,CPT1C,TBKBP1,AMOTL1,TRPM2,SYT17,NDUFB5,PTPRG,PABPC1L,AP1B1,LTB4R,TRIM66,CHD7,ZNF827,DECR1,TMEM184A,KDM2A,VGF,DTNBP1,NBEA,TTC3,PNPLA4,RFC4,ZCCHC14,GON4L,WDPCP,DLG4,KIAA1586,GNL1,SATB2,MEGF11,MED16,DCBLD2,G6PD,DNAJA3,ACP1,IFT140,MDN1,PDCD11,XRCC4,NCOR2,BRAF,C10orf2,NFX1,RCAN1,RTN4,MLH1,DNAJC22,INPP1,GIGYF2,NEDD4,ABL1,PMPCA,UPF2,FER1L5,WDFY3,PACS1,MMAA,YIF1A,ZFP62,DDX50,HELZ,STX18,ATM,MYOM2,APAF1,LRRC41,LETM1,PHF3,MVK,NF1,ATRX,SLC52A3,KIF5A,FANCD2,TRPM6,PLOD1,BCOR,STK33,SNAPC4,SMARCB1,SLC30A7,RTN1,ZNF804A,LONRF2,THADA,YLPM1,MYH3,GPATCH1,KIAA0922,B3GNTL1,NDUFA6,OGG1,CARM1,FBXW4,SIRT6,CMIP,ITPA,ARRDC3,TMEM216,SOX4,KMT2C,TCTN1,SERGEF,CHAF1A,GEMIN5,TMEM132B,CCDC3,SUFU,CSMD3,CLU,EME1,ZC3H8,MTCH1,TNRC6A,SLC12A7,DCTN3,FN1,ZCCHC8,SCART1,PAX2,PCSK7,SMG7,EVPL,QSER1,SIPA1L3,MCAM,WDR27,SEMA3D,ZCCHC7,PRF1,NRIP1,ATP6V0D1,LRP3,N4BP2,MTHFD1,ZNF629,HBG2,KRT20,PDE4A,ELP3,JMJD1C,ZBED4,WWC1,EIF2A,PRDM1,ANKRD20A4,AGAP1,DNAH14,ISG15,SYCP2L,MYBBP1A,EP400NL,FAT1,HK2,ZFP90,TMEM182,TBCK,DMXL2,FEZ2,PCNT,CELSR3,TMEM183A,TNXB,MYO7A,SMARCA4,COBLL1,VPS18,NVL,ZNF142,MET,ZNF460,HTRA2,MAML3,NARS2,TFCP2,PARP2,GRHL3,METTL15,R3HDM1,ATXN1,EDEM2,ATP8B2,UBR4,ARMC4,ALAD,DUS3L,IKZF4,HYAL3,SRFBP1,SCARB1,DISP1,SMG1,NSUN6,ATF7IP,MFSD10,SFI1,PRKCH,SCN1B,KDELC1,SHMT2,ERI3,RPS6KB2,KDM6B,ARNTL2,CRIM1,ASAP3,SCFD2,METTL23,MEN1,TMEM187,SYMPK,RERE,DAGLB,WDR35,ZRANB2,MBD6,TATDN1,ZAK,MMP16 |
| 8.851e-04 | -7.03 | V$USF_01 | MSigDB lists | V$USF_01 | 244 | 49 | 17758 | 2279 |
CGN,ATP6V1A,NFX1,ATF7IP,GYG1,RLF,DHX35,GIGYF2,RSPRY1,FAM192A,ATIC,VGF,DCTN4,SLC38A2,GTF2H1,IGF2BP1,ETV1,ZCCHC7,PRPS1,NUDC,BDNF,ATF4,APEX1,SIGMAR1,MON1A,AKAP12,MCM2,ODC1,TRIM37,CPT1A,NOP58,BATF3,RPA1,DDX3X,TOM1L2,GTF2A1,ZBTB8OS,PER1,HSPBAP1,SET,VPS37B,TRMT2A,EME1,BMP4,PFDN2,KDM4C,KAT6A,USP15,NIT1 |
| 8.924e-04 | -7.02 | HOELZEL_NF1_TARGETS_UP | MSigDB lists | HOELZEL_NF1_TARGETS_UP | 130 | 30 | 17758 | 2279 |
ARHGAP26,TNIK,TRNP1,THSD4,ANK2,UPP1,CLSTN2,ATXN1,PHACTR2,SPATS2L,PHLDA2,PAG1,IGSF1,DCBLD2,KISS1R,PCDH7,GLS,NAV1,PXDN,S100A10,ITGA2,AHNAK2,HSPB8,UTS2,MET,NRIP1,PDLIM5,SOX6,MOSPD1,HS2ST1 |
| 8.924e-04 | -7.02 | KEGG_SELENOAMINO_ACID_METABOLISM | MSigDB lists | KEGG_SELENOAMINO_ACID_METABOLISM | 26 | 10 | 17758 | 2279 |
SEPHS2,GGT1,METTL6,WBSCR22,MARS,GGT7,AHCYL1,METTL2B,MAT2A,AHCYL2 |
| 8.935e-04 | -7.02 | GSE17721_LPS_VS_POLYIC_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDM_DN | 189 | 40 | 17758 | 2279 |
EFNB2,ZNF292,CLK1,ACTR3,SIRT7,UBXN1,TRPM6,CENPB,SBF2,RTN4,GRINA,MFHAS1,SCN1B,SOCS6,NDRG4,VAPB,PTGS1,KIAA0922,PLEKHA2,TBC1D8,CLK2,KRT20,HMBOX1,PXN,GCNT2,MYO10,LGALS1,SOX4,ENC1,C8orf33,DDX60,DCBLD2,CAMK2D,RBBP8,SYNGR2,TSSC1,MAGI1,TSPAN5,XPO6,USP15 |
| 8.939e-04 | -7.02 | Homologous DNA Pairing and Strand Exchange | REACTOME pathways | R-HSA-5693579 | 42 | 14 | 8202 | 1117 |
EXO1,RFC4,RFC3,RBBP8,BRCA2,PALB2,XRCC2,RAD51B,TOP3A,ATM,ATRIP,BRCA1,RMI1,RPA1 |
| 8.939e-04 | -7.02 | BMAL1:CLOCK,NPAS2 activates circadian gene expression | REACTOME pathways | R-HSA-1368108 | 42 | 14 | 8202 | 1117 |
ARNTL2,CHD9,HIF1A,NPAS2,PER1,ARNTL,SMARCD3,TBL1X,NCOR1,BHLHE40,NRIP1,NOCT,CARM1,NAMPT |
| 8.952e-04 | -7.02 | GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_DN | 183 | 39 | 17758 | 2279 |
BCKDK,MCM6,SCAMP3,DROSHA,PTPRA,TFIP11,VTI1A,SAFB2,MCM9,SMARCB1,SLC30A7,ANXA7,SREBF2,ANAPC10,C16orf58,PRADC1,MRPL21,FXN,PLEKHA2,GARS,WBSCR22,LGALS1,VIM,UBE2E1,C1orf122,MRPL36,GNG2,DUS3L,ZNF330,DUSP19,FTSJ1,SURF1,TBPL1,XPNPEP1,ACP1,ZNF32,ANXA2,COPS6,DHCR7 |
| 8.952e-04 | -7.02 | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_DN | 183 | 39 | 17758 | 2279 |
DROSHA,ANKRD17,CCDC53,DDX18,URB2,PRKAB2,TRAK1,VTI1A,JMJD6,GDPD5,SAFB2,SYNJ1,FRRS1,APLF,POLR1B,NDUFA6,FBXO31,ERI3,LPCAT1,AUP1,GARS,AP4B1,MANBAL,C8orf33,NAPEPLD,NOP58,VAC14,C1orf122,MRPL36,EXOC6,SLC39A14,TRMT5,ARL4A,SDCCAG8,DUSP19,CCDC85B,TSSC1,SQLE,YEATS2 |
| 9.021e-04 | -7.01 | MAGEA10 (MAGE family member A10) | protein interactions | 4109 | 32 | 12 | 16036 | 2270 |
FAM216A,TADA3,PES1,ERI1,VPS72,CUX1,GTF2IRD1,POU2F1,SATB2,QSER1,NRIP1,YEATS2 |
| 9.030e-04 | -7.01 | GCM_ZNF198 | MSigDB lists | GCM_ZNF198 | 113 | 27 | 17758 | 2279 |
EPM2AIP1,PTBP2,ANKRD17,HECTD3,ZFP14,MINA,QSER1,ARID1A,MARCH6,IKBKAP,TRAPPC6B,FOXO3,CRYBG3,FAM8A1,ZNF655,SPAG9,EIF4ENIF1,KIDINS220,KPNA3,HNRNPH3,LEMD3,LUC7L3,RABGAP1L,CELF1,ZMYM2,DMTF1,CEP170 |
| 9.102e-04 | -7.00 | ATTCTTT,MIR-186 | MSigDB lists | ATTCTTT,MIR-186 | 263 | 52 | 17758 | 2279 |
SNX27,DNM3,RBFOX2,C16orf52,PID1,CSNK2A1,ZFP36L1,IGF2BP2,PRPF39,TGFBR2,MBNL1,GABPB2,SCAF8,ZNF608,EIF2S2,UBE3A,JAG1,PDS5B,CELF1,AHCYL1,AMOT,ZMYM2,PABPC1,MOSPD1,SRPK2,PFKFB4,ZCCHC14,EIF4E3,WDFY3,RB1CC1,KCNMA1,ZC3H18,MEX3B,PRDM1,PNN,ENC1,MBNL2,SLC23A2,OXSR1,ZFAND3,DDX3X,EPN2,BAZ2B,NME7,SH3RF1,KIAA0355,RIOK3,PURB,RBM26,RPS6KB1,TMEM182,MORC2 |
| 9.133e-04 | -7.00 | macromolecule methylation | biological process | GO:0043414 | 223 | 46 | 16441 | 2138 |
ASH1L,KMT2E,ATRX,ATF7IP,CHD5,METTL16,SUV39H2,TRMT13,TRMU,ALKBH8,HIST2H3D,CTR9,ETF1,FBL,TRMT10A,PRMT5,KMT2A,PRMT3,FTSJ3,CARM1,GATAD2B,METTL1,KMT2D,SETD1B,WDR61,RNMT,BAZ2A,SETD2,EHMT1,METTL2A,PCMT1,METTL15,HIST1H4J,SETD7,KMT2C,MEN1,DOT1L,NSD1,EHMT2,TRMT5,CAMKMT,FTSJ1,TRMT2A,SETD6,SMYD3,METTL2B |
| 9.177e-04 | -6.99 | transition metal ion binding | molecular function | GO:0046914 | 1395 | 222 | 16491 | 2164 |
CYP24A1,ADAM19,MYCBP2,PHF3,TRIM16,KMT2E,ATRX,POLR1A,RCHY1,PLOD1,RNF43,ADAMTS6,HLTF,SIRT2,PRKCA,BIRC2,CUTC,UBR5,SKI,ABL2,MMP7,ZFHX3,LONRF2,ANAPC11,ZEB1,RNF111,ME1,KDM5C,HRG,ZNRD1,FXN,ZNF3,ZMYM2,TRIM14,DPF3,DTNB,TRIM13,RBCK1,ZNF195,SIRT6,PPARG,LIMA1,BAZ2A,NR6A1,LVRN,ATOX1,EHMT1,MSRB3,BRCA1,ZDHHC14,KMT2C,ZNF91,MLLT10,ZNF622,RBSN,SUPT4H1,ZGRF1,RAD18,GATA6,SH3RF1,CHD3,NSMCE1,ADAM9,XPNPEP1,CCNB1IP1,BMI1,ZNF598,RNF214,ZMAT3,LPP,HERC2,AOC3,TRIP6,ZCCHC8,SEC24D,DPF2,MEX3A,TRIM15,RSF1,C11orf54,RLF,TIMM10,CHD5,RSPRY1,RNF40,RNF141,RBM20,RNFT2,P3H1,ALKBH8,CNOT4,LRSAM1,ZCCHC7,NT5E,SCAF11,GATAD2B,ZNF675,TIMM8B,HBG2,USP49,AOC2,TYW1,TBXAS1,MEX3B,TRIM37,MTR,NR2F1,ARIH2,PHF6,PDLIM1,EHMT2,ALKBH3,ZZEF1,ZCCHC6,DPEP1,PDLIM5,ZFHX2,RNF114,MPI,CYLD,ASH1L,LIN28B,GTF2H2C,RPS29,UROD,RNF24,ZMAT2,EEA1,RING1,FDX1,TRIM66,PHC2,CAD,IDI1,ZSWIM7,KDM2A,UBR1,ZDHHC6,MMP14,INTS12,RNF2,TTC3,ZFP37,PEG10,KMT2A,TMLHE,SEC24A,PCGF3,ZCCHC14,KMT2D,DDX41,ADAM32,MARCH6,CA5B,UBR4,SNCA,VDR,TAF2,ZFAND3,SMAD3,FBXL5,BAZ1A,RANBP2,KDM4B,ALAD,ADNP,KLF4,NSMCE2,MBTD1,LARGE,PAM,ALKBH1,TRAF3,RNF130,FUS,MID1,TRIM36,MORC2,DBF4,NFX1,SF3A3,JMJD6,MYNN,TRIM22,ZNF346,ABL1,ADH5,SUV39H2,TAF3,SEC24C,PMPCA,PRICKLE2,LTN1,FBXL19,MICAL3,MARCH9,PXN,ADAMTSL3,KDM5B,ZFYVE1,KDM5A,ZMYM5,TOP3A,ZNF407,NAPEPLD,ZRANB3,RERE,NSD1,BAZ2B,ZDHHC11,ADAT2,ZNF330,AGTPBP1,RNF138,FNTB,USP20,ZRANB2,NR2F2,MMP16,KDM4C,ZSWIM6,KAT6A |
| 9.208e-04 | -6.99 | DISC1 (disrupted in schizophrenia 1) | protein interactions | 27185 | 124 | 31 | 16036 | 2270 |
TNIK,ATF4,PCNT,ACTG1,PAFAH1B1,KATNAL1,TFIP11,TRIO,PDE4B,ATF7IP,CEP126,NUP160,ZNF197,ARIH2,EIF3H,MLLT10,DST,DYNC1H1,EXOC1,RBSN,BICD1,KANSL1,CEP290,AGTPBP1,STX18,EXOC4,XPNPEP1,CEP63,CLU,CEP170,SPTAN1 |
| 9.246e-04 | -6.99 | ribonucleoside monophosphate metabolic process | biological process | GO:0009161 | 211 | 44 | 16441 | 2138 |
NDUFA5,AK2,ATP6V1A,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,CAD,AMPD3,GART,NDUFV1,ENTPD5,ATP5G2,ATIC,MYH3,CMPK1,NDUFA6,FXN,PRPS1,NT5E,PFKFB4,BDNF,PPAT,UPP1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,COQ9,HK2,SURF1,UMPS,NDUFS5,ADK |
| 9.261e-04 | -6.98 | CXXC5 (CXXC finger protein 5) | protein interactions | 51523 | 7 | 5 | 16036 | 2270 |
SMAD3,VDR,SKIL,ATM,SMAD7 |
| 9.261e-04 | -6.98 | positive regulation of transcription elongation from RNA polymerase II promoter | biological process | GO:0032968 | 14 | 7 | 16441 | 2138 |
PAF1,CTR9,ELL,BRD4,WDR61,SUPT6H,CDC73 |
| 9.261e-04 | -6.98 | cAMP catabolic process | biological process | GO:0006198 | 14 | 7 | 16441 | 2138 |
PDE2A,PDE4A,PDE3B,PDE10A,PDE3A,PDE8B,PDE4B |
| 9.274e-04 | -6.98 | HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1 (H)) | protein interactions | 3187 | 167 | 39 | 16036 | 2270 |
USP7,C9orf78,CUL7,CUL4A,FN1,NFX1,IKBIP,MBNL1,HNRNPA3,TOM1L1,NAMPT,SHC1,PTRF,TNPO3,HIBCH,PEG10,SRRM2,IPO11,HNRNPM,PRAME,TSTA3,SIRT6,SMARCAD1,UBC,YTHDF2,RPA1,RANBP2,AHNAK,SYNCRIP,LSM14A,HNRNPR,HNRNPH3,COPS5,CDK9,CUL2,GPN1,NCBP2,FUS,COPS6 |
| 9.283e-04 | -6.98 | CLK1 (CDC like kinase 1) | protein interactions | 1195 | 24 | 10 | 16036 | 2270 |
CLK1,LUC7L3,TRA2A,PRPF4,NCOR1,PRMT5,UBL5,PDE9A,ISG15,SRPK2 |
| 9.283e-04 | -6.98 | NHP2 (NHP2 ribonucleoprotein) | protein interactions | 55651 | 24 | 10 | 16036 | 2270 |
FN1,LIN28B,JMJD6,RNF2,DKC1,FBL,BMI1,EIF5B,NOP58,NEDD4 |
| 9.283e-04 | -6.98 | CRCP (CGRP receptor component) | protein interactions | 27297 | 24 | 10 | 16036 | 2270 |
BCCIP,TCF12,POLR3D,POLR3E,CRCP,SHMT2,RBM26,POLR3B,POLR1C,POLR3A |
| 9.338e-04 | -6.98 | ZAMORA_NOS2_TARGETS_DN | MSigDB lists | ZAMORA_NOS2_TARGETS_DN | 91 | 23 | 17758 | 2279 |
PEA15,SARS,IFNGR2,JUP,NFIA,MYH9,RIPK1,ZFP36L1,RABAC1,SOX4,AP1B1,SLC6A8,FKBP3,UBC,FDX1,ATP5D,DYNC1H1,RARS,EIF2S2,SCN1B,HSPB8,IFITM2,LONP1 |
| 9.356e-04 | -6.97 | RRP9 (ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)) | protein interactions | 9136 | 28 | 11 | 16036 | 2270 |
WDR36,THOC5,CUL7,TRA2A,SIRT7,NOL6,CSNK2A1,VIM,ZNF346,FBL,PUM3 |
| 9.356e-04 | -6.97 | CDC7 (cell division cycle 7) | protein interactions | 8317 | 28 | 11 | 16036 | 2270 |
PAF1,MCM6,MCM10,RAD18,CDK9,MCM5,CDK4,ORC5,DBF4,MCM2,CHAF1A |
| 9.413e-04 | -6.97 | Trans-sulfuration and one carbon metabolism | WikiPathways | WP2525 | 31 | 11 | 4455 | 564 |
MTHFD2,PSAT1,SHMT2,MTHFD1L,AHCYL1,MTHFD2L,PHGDH,MTR,MAT2A,AHCYL2,MTHFD1 |
| 9.470e-04 | -6.96 | POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | MSigDB lists | POSITIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 119 | 28 | 17758 | 2279 |
ATF4,TRERF1,FOXO1,NPAS2,PPARGC1B,TCF3,SMARCD3,ATF7IP,ARID1A,RSF1,SUPT5H,FOXO3,BMP6,MAP2K3,SMAD3,DYRK1B,NSD1,SUPT4H1,SMARCC1,PHF5A,HIF1A,ARNTL,MKL2,TNFRSF1A,GTF2H1,RUNX1,NRIP1,MAML3 |
| 9.616e-04 | -6.95 | bone-femur-other-chondroblastoma | COSMIC cancer mutations | bone-femur-other-chondroblastoma | 196 | 41 | 17775 | 2278 |
IMMP2L,DNM3,NSUN6,CLSTN2,SBF2,SPATS2,PTPRG,ETFB,IQGAP2,SLC39A11,PCDH7,ZNF804A,TAF3,ZFYVE28,INTS7,RDX,FHIT,TOP1,CHD9,AKAP8L,PRIM2,PREX1,MARS,LAMA2,EVI5,SYT1,ARMC4,ZFAND3,LRP1B,TASP1,SMARCC1,ORC5,LARGE,BCAS3,TSSC1,CSMD3,TMEM117,KIAA1328,EIF2B3,TBCK,SMG1 |
| 9.616e-04 | -6.95 | RIBOSOME_BIOGENESIS_AND_ASSEMBLY | MSigDB lists | RIBOSOME_BIOGENESIS_AND_ASSEMBLY | 18 | 8 | 17758 | 2279 |
EXOSC2,GEMIN4,EIF2A,DKC1,FBL,NOLC1,NOP58,NOP56 |
| 9.616e-04 | -6.95 | CTACTAG,MIR-325 | MSigDB lists | CTACTAG,MIR-325 | 18 | 8 | 17758 | 2279 |
HNRNPH3,ZNF654,ARRDC3,CELF1,ARL5B,CSNK1A1,TMEM206,TMCC1 |
| 9.679e-04 | -6.94 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | molecular function | GO:0016893 | 39 | 13 | 16491 | 2164 |
RPP30,POP1,EXO1,SLX4,DROSHA,APEX1,AGO2,TATDN3,FAN1,POP5,TATDN1,RNASEH2B,EDC3 |
| 9.705e-04 | -6.94 | ACTGCCT,MIR-34B | MSigDB lists | ACTGCCT,MIR-34B | 208 | 43 | 17758 | 2279 |
TCF12,MYCBP2,CELSR3,ARID2,AP1B1,PTPRG,FOXP1,ARID1B,AHCYL2,IQGAP2,NAV1,JAG1,JAZF1,MYC,RDX,ARHGAP1,ZNF148,MET,ZNF3,CNOT4,CDK6,MOSPD1,NAV3,MYB,HMBOX1,BRD4,SFSWAP,ANK2,FOXN3,RAP1GAP2,ARRDC3,MARCH6,FAM126B,SOX4,ARL5B,RAB10,MAT2A,PURB,RPS6KB1,CNOT6,SENP3,MAGI1,AP2S1 |
| 9.787e-04 | -6.93 | nucleobase metabolic process | biological process | GO:0009112 | 69 | 19 | 16441 | 2138 |
PPAT,UPP1,ADSL,APRT,IMPDH2,NT5C3A,CAD,CAT,AMPD3,HPRT1,GART,ATIC,UMPS,NT5C,CMPK1,NT5M,ADK,PRPS1,NT5E |
| 9.801e-04 | -6.93 | phosphorus metabolic process | biological process | GO:0006793 | 2000 | 305 | 16441 | 2138 |
PTP4A1,PRDX6,PRKAB2,NT5C3A,PRKCA,ABHD6,SYNJ1,LPIN1,NEK6,ATP5G2,SUCLG2,ME1,FNIP2,FXN,CDK6,PPM1K,NRAS,UPP1,PTPRM,EYA3,STOML2,TRRAP,SSU72,CCNT1,RIOK1,PTPN14,MEF2C,SLK,TRIO,AK6,PIK3R4,DPM3,PLA2G12A,TGFBR2,NDUFS7,PRKCE,PI4KB,ENTPD5,MYC,ATIC,PIGG,MAP3K12,LPCAT1,PRPS1,PPA1,FDFT1,HMGCR,FADS1,PEA15,SIK3,GTF2H3,BDNF,SYNGAP1,RB1CC1,IDH3G,PTPN12,IMPDH2,PLCB1,IRS1,CAT,NME7,CDK9,SURF1,RIOK3,UMPS,BPNT1,MAP2K4,MAP2K5,BIRC6,PAFAH1B1,ATP6V1A,PDK4,NDUFB5,OLA1,DDR2,PTPRG,LCLAT1,HSPA1A,PDE3A,NDUFB3,FLAD1,PRKD3,SHC1,LPIN2,NT5C,CMPK1,PXK,MTHFD2L,MGLL,CDK12,LYST,GARS,BRD4,PDK1,PI4KAP2,DLG4,ATP6V0A1,GALK2,KCNH3,NUDT15,STK10,ERC1,FGFR1,PDE8B,SNCA,TAMM41,CAMK2D,DCXR,HIPK2,G6PD,PEMT,ACP1,RPS6KB1,HMGA2,SSH2,SERINC5,BRAF,GAS6,IP6K2,IKBKAP,TGFB2,RNASEH2B,RPS6KA5,INPP1,RSRC1,PSMF1,DCTPP1,ABL1,NPRL2,ACOT11,MAP3K14,NT5M,SPTAN1,CLK2,PFKFB4,FGF9,PXN,AGPAT4,LDHA,ADSL,TBRG4,PTK2,APTX,PPIP5K2,PDE3B,UBC,OXSR1,TRIB3,PLPPR2,COQ9,SRD5A3,ATM,PTPN4,NDUFS5,GPAM,BMP4,PGAM5,ADK,MTMR1,STK4,PIGM,MVK,NF1,PTPRA,TRPM6,CSNK2A1,STK33,COX10,MAP2K3,ABL2,AMPD3,PHKA1,PPCDC,MYH3,NDUFA6,OGG1,PRKACB,TIMM50,PTPRK,SRPK2,TNK2,ITPA,CDK4,GPCPD1,GMFB,COL4A3BP,KSR2,PITPNB,CAV1,KCNH2,SGK2,DLST,DYRK1B,HPRT1,GATA6,PPP3CC,USP15,SEPHS2,XYLB,TTN,PIGN,AK2,CLK1,TAF1,GPAT3,SMAD7,LAMTOR3,MAPK8IP3,NAMPT,PDE10A,GTF2H1,SYNJ2,PNPLA3,ALDH18A1,N4BP2,MTHFD1,NT5E,CAMKK2,PDE4A,PPAT,ELOVL6,OBSCN,PSMA1,MEX3B,EIF2A,VAC14,PGD,SPAG9,IRAK2,FDPS,TBPL1,HK2,CASS4,PTP4A2,BRSK2,TBCK,PDE9A,NDUFA5,SUCLG1,LPCAT2,NTSR1,PIGH,PPP2R2A,RIPK1,LPCAT3,PUDP,PIBF1,RIOK2,CAD,IDI1,GRIN2C,FGGY,RPS6KL1,IKBKB,FHIT,ADCK4,MET,MCEE,ACSL5,AKAP13,TPK1,ATP5D,ABHD3,DUSP19,MUTYH,SMG1,TNIK,BCKDK,MINK1,SULT1C2,SH2D3A,MAP3K13,CAMK1,PDE4B,TKFC,CHCHD10,APRT,CSNK1A1,PIP4K2A,PTPN2,PRKCH,GART,NDUFV1,CPNE7,HSD17B12,SLC25A1,RPS6KB2,TOP1,GPHN,FGF2,SMARCAD1,TEX14,SULT4A1,MEN1,PDE2A,PEAK1,PIK3CB,NAPEPLD,SMPDL3B,HSPA1B,ALG5,SERINC1,EIF2S1,RPS6KC1,ZAK |
| 9.828e-04 | -6.93 | Mitochondrial tRNA aminoacylation | REACTOME pathways | R-HSA-379726 | 21 | 9 | 8202 | 1117 |
NARS2,GARS,WARS2,LARS2,RARS2,AARS2,FARS2,HARS2,YARS2 |
| 9.848e-04 | -6.92 | MOOTHA_HUMAN_MITODB_6_2002 | MSigDB lists | MOOTHA_HUMAN_MITODB_6_2002 | 418 | 76 | 17758 | 2279 |
CYP24A1,NDUFA5,SUCLG1,PTPRA,PDK4,NDUFB5,SLC25A21,COX10,FDX1,MRPS30,NDUFB3,FARSA,DECR1,NRF1,PPID,ATP5G2,MRPS27,SSBP1,NDUFA6,FXN,OGG1,LONP1,MPST,ACSL5,ACADS,PDK1,MTIF2,CPOX,CA5B,POLG2,DLST,ODC1,ATP5D,PYCR1,TIMM44,GLS,HLCS,TIMM17A,SLC25A11,TXN2,MUTYH,MTCH1,BCKDK,AK2,LARS2,FARS2,SLC25A12,OPA1,TIMM10,SLC1A1,ETFB,NDUFS7,MRPS11,SLC25A20,SHMT2,ALDH18A1,PCK2,TOMM34,LYPLA2,SLC25A1,MTHFD1,TIMM8B,WARS2,PCCA,ABCF2,IDH3G,BCS1L,MRPS10,CYB5B,CPT1A,MFN2,ETFDH,MTHFD2,TRAP1,SURF1,APAF1 |
| 9.882e-04 | -6.92 | RAMALHO_STEMNESS_UP | MSigDB lists | RAMALHO_STEMNESS_UP | 196 | 41 | 17758 | 2279 |
TRIP6,ANKRD17,RARS2,TMEM183A,RSL1D1,STAM,TOM1L1,NOP56,DCTPP1,PTPN2,CAD,PEX7,RRN3,MPHOSPH10,COPS4,DNAJB6,SLC38A2,SUCLG2,GSTA4,PPA1,GARS,LIMA1,UPP1,EIF3J,SMARCAD1,ELOVL6,PACRGL,USP10,MRPS10,NOP58,LSG1,EPRS,ELP2,INTS5,RNF138,SLC4A7,ADAM9,UMPS,C12orf45,ZMAT3,GCSH |
| 9.943e-04 | -6.91 | GSE17721_4_VS_24H_CPG_BMDM_DN | MSigDB lists | GSE17721_4_VS_24H_CPG_BMDM_DN | 190 | 40 | 17758 | 2279 |
SARS,IFT57,MIF4GD,SEC24D,ZFP36L1,GRINA,AARS,NDUFB3,SLC25A20,ZDHHC6,TRIAP1,SLC38A2,KDELC1,ANKRD24,PAK1IP1,TTC3,NRIP1,TMLHE,ACSL5,ARNTL2,FBXW4,DNMBP,ZNF124,STAG1,WDFY3,RNMT,IMPDH2,SON,ZBTB25,PLIN2,MGAT2,COQ9,SRD5A3,DNAJC12,SLC25A19,ADAM9,SIL1,ARC,IGBP1,PTPN14 |
| 9.943e-04 | -6.91 | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP | MSigDB lists | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP | 190 | 40 | 17758 | 2279 |
EPM2AIP1,FEZ2,PHF3,RBM33,FEM1C,PAFAH1B1,C16orf52,NECAP1,BTBD9,GRINA,HLTF,CLINT1,FAM8A1,PAG1,NDUFB3,SLC30A7,FKBP1A,NRF1,SEC24C,ARMC5,IKBKB,IPP,CELF1,PCK2,PFKFB4,NAA38,CAMKK2,POLK,ZFYVE1,TEX14,MINA,COL4A3BP,BMS1,CA5B,PEAK1,ZNF251,KPNA1,ALG5,CNOT6,MED20 |
| 9.943e-04 | -6.91 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 190 | 40 | 17758 | 2279 |
KCTD7,TNIK,SHQ1,RPS29,SLC2A1,ATF7IP,NUP43,DENND3,POGZ,GIT2,CDC73,ANXA10,PPID,ZDHHC6,IKBKB,PIGG,RNF111,VAPB,CORO1A,KIAA0922,CEP135,NRIP1,AGL,AKAP11,CASP8AP2,LYST,PRKACB,TRIM13,ZNF480,RAP1GDS1,POLR2A,ZBTB25,PDE8B,HLA-DMA,BAZ1A,CAT,KIAA0355,SNAP23,CNDP2,KAT6A |
| 9.943e-04 | -6.91 | V$HSF_Q6 | MSigDB lists | V$HSF_Q6 | 190 | 40 | 17758 | 2279 |
ZNF706,ANKRD17,ATP6V1A,PTPRA,ZBTB37,DPF2,TNXB,PLOD1,PPP2R2A,JMJD6,TNKS1BP1,HSPA1A,IL17RE,RTN1,SHC1,PHF5A,PPID,TNPO3,CORO1A,GEMIN4,SERPINH1,PPP1R9B,MSX1,GPHN,IFT43,EIF4A2,NFIA,SNAP25,MARCH6,R3HDM2,UBE2K,PHF6,HSPA1B,ZBTB25,ITPRIPL1,GATA6,RPL28,GTF2A1,CSRNP1,MID1 |
| 9.975e-04 | -6.91 | adrenal_gland-adrenal_gland-pheochromocytoma-benign | COSMIC cancer mutations | adrenal_gland-adrenal_gland-pheochromocytoma-benign | 227 | 46 | 17775 | 2278 |
DCTN3,HERC2,BRAF,RBM33,BIRC6,ZCCHC8,NF1,ATRX,LPCAT2,ZNF280C,CACNA1H,SMARCA4,ZNF107,WDR26,SPATS2,PIBF1,GIGYF2,FAM8A1,CMTM3,ABCA7,CAD,PDZD2,CTR9,ZEB1,CAV2,PTPRK,SCAF11,COL17A1,NRAS,ALG6,ZNF195,ANKRD20A4,ZNF407,EXOC6,DYNC1H1,ASCC3,AHNAK,PALB2,VCAN,DNAH17,MSH3,IFT140,RWDD2B,HEATR1,WDR33,ZNF598 |
| 9.981e-04 | -6.91 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN | 184 | 39 | 17758 | 2279 |
ZNF254,SART1,BCAS4,RWDD1,UBXN1,LAGE3,GDPD5,REEP5,MFHAS1,POGZ,DCTPP1,TADA3,DDX56,ATIC,DNAJB6,ZNF85,GMDS,HSD17B12,HNRNPM,SERBP1,SPTAN1,MTHFD1,TOP1,PPAT,SKIV2L2,PARP2,PSPC1,MEN1,DENND4A,UBR4,TMEM186,EXO1,UBAP2,TRRAP,BAZ2B,COPS5,FDPS,ZCCHC6,TXN2 |
| 9.981e-04 | -6.91 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 184 | 39 | 17758 | 2279 |
ASCC1,EGR1,TRAK1,NHS,SSBP2,SLC25A44,SLC9B2,RNASEH2B,COX10,FDX1,AHCYL2,DENR,DECR1,BRE,FGGY,SOCS6,B3GNTL1,PRF1,PPA1,MYB,PAQR6,DBN1,PMS1,NRAS,OSBP2,STAMBP,ZFYVE1,C2orf76,PALLD,SOX4,DNAH14,BTBD11,BATF3,SLC39A14,NME7,GSTO2,ADAT2,SQLE,PTPN14 |
| 9.981e-04 | -6.91 | GSE31082_DN_VS_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_CD4_SP_THYMOCYTE_UP | 184 | 39 | 17758 | 2279 |
WDR75,DNAJC2,C9orf78,AUH,TTC27,SF3A3,VARS,RBM19,RPS6KA5,PDCD5,PELP1,NEDD4,SFR1,KIAA1958,SNW1,SUB1,PHF5A,ATP5G2,NUP133,ERI1,CCDC40,PRADC1,ERI3,NT5M,PPA1,HNRNPM,CEP128,MTHFD1,ACSL5,NAA38,PPAT,MTHFD1L,DCUN1D5,DDX49,ZRANB3,SLC7A1,HMBS,NMD3,C7orf26 |
| 1.003e-03 | -6.90 | ABCE1 (ATP binding cassette subfamily E member 1) | protein interactions | 6059 | 229 | 50 | 16036 | 2270 |
SRM,USP7,NDUFA5,AK2,CUL4A,HM13,JUP,DDX18,ATP6V1A,MFGE8,SIRT7,RPS29,NAT10,PPP2R2A,AP1B1,AARS,FLNB,ASNS,S100A10,DSG2,VAPB,SUCLG2,ETF1,RNF2,EXOSC4,POLR1B,FBL,PEG10,CPSF3,CD44,SRRM2,GNG5,TMPO,SF3A1,RFC4,APEX1,SSFA2,SFXN4,ANK2,TSN,VIM,DKC1,ABCF1,EIF3H,DCXR,SNAP23,FDPS,PFDN2,MDN1,PRKAR2A |
| 1.005e-03 | -6.90 | SBNO1 (strawberry notch homolog 1 (Drosophila)) | protein interactions | 55206 | 10 | 6 | 16036 | 2270 |
RTN4,SUB1,SRSF2,PRMT5,UBR4,SEC24C |
| 1.005e-03 | -6.90 | FDXR (ferredoxin reductase) | protein interactions | 2232 | 10 | 6 | 16036 | 2270 |
POU2F1,CBWD1,FHIT,TBC1D22A,FDX1,TSSC1 |
| 1.005e-03 | -6.90 | POLR3G (polymerase (RNA) III (DNA directed) polypeptide G (32kD)) | protein interactions | 10622 | 10 | 6 | 16036 | 2270 |
POLR3D,POLR3B,POLR1C,RBM28,POLR3A,POLR3E |
| 1.005e-03 | -6.90 | negative regulation of mitotic nuclear division | biological process | GO:0045839 | 49 | 15 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,TOM1L2,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,BMP4,MAD2L2,ANAPC4,UBE2E1,TOM1L1 |
| 1.006e-03 | -6.90 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 837 | 138 | 17758 | 2279 |
CYP24A1,PIGM,CNTNAP3,PLOD1,BCOR,GABPB2,PABPC4,SMARCB1,PCDH7,DST,ZFYVE28,ANAPC10,PCOLCE2,ZNF85,PRADC1,CCDC121,FUT11,TRIP13,TMPO,CEP128,DEAF1,KLHL23,PPARG,UPP1,TCEB3,KIF15,MSRB3,BRCA1,PITPNB,FLVCR1,SLC9A5,TAF9B,DDX3X,BRCA2,INSIG1,HSPBAP1,MKL2,EME1,VASH2,ZMAT3,EFNB2,HERC2,EPM2AIP1,MCM6,EGR1,SEC24D,CLK1,C16orf52,HES6,CCDC47,PARN,SH2B3,RNF141,KIAA1958,MCAM,SLC7A11,SAMD13,COQ3,AGL,N4BP2,AKAP11,SAMD3,MYB,FADS1,IFRD1,KIAA1143,PPAT,MEX3B,LYRM7,PHF6,VPS13C,ATAD5,SPAG9,BICD1,SYNCRIP,NSF,BIVM,TBL1X,ID1,PAFAH1B1,COBLL1,ST3GAL6,MCM9,EEA1,STAM,SLC39A1,RPGRIP1L,CHD7,PHC2,ANKRD13A,PRKD3,IDI1,CMPK1,TMEM136,DENND1A,PERP,SAP30,TMEM200A,RFC4,PTBP2,FAM111B,ARHGEF10,POU2F1,SATB2,NHSL1,ENC1,NUDT15,RAD54B,DCBLD2,RPS6KB1,MCM10,KIF5C,ID2,CCDC7,OPA1,ZNF346,RSRC1,RMI1,SFR1,HAS3,FBXO31,NT5M,TOP1,ARNTL2,DDHD1,FAM71E1,FGF2,PSMC3IP,SLC35G1,TPM4,SCMH1,RSBN1,FAM126B,TRIB3,DDX50,PXDN,MIPOL1,CORO2B |
| 1.007e-03 | -6.90 | mitochondrial envelope | cellular component | GO:0005740 | 679 | 114 | 17570 | 2233 |
IMMP2L,CYP24A1,NDUFA5,LETM1,SUCLG1,NDUFAF2,MRPL10,PDK4,NDUFB5,SLC25A21,SLC25A44,SLC9B2,PRKCA,COA1,COX10,LPIN1,CIAPIN1,AMBRA1,MRPS30,NDUFB3,MIEF1,ABCA12,PMAIP1,ATP5G2,LETM2,MRPS27,RMDN3,ADCK4,NDUFA6,SLC25A23,MTHFD2L,TMEM14C,HTRA2,MPST,TIMM50,ACSL5,GDAP1,SFXN4,CPOX,NLN,MCL1,FOXRED1,FLVCR1,MPC1,MGST1,ATP5D,STOML2,SNCA,TIMM44,TAMM41,DDX3X,TIMM17A,PEMT,MPV17,SLC25A11,RPS6KB1,FIS1,CLU,UQCC2,FAHD1,SLC25A26,MTCH1,HERC2,AK2,HSD17B10,SLC25A12,LETMD1,CHCHD10,OPA1,TIMM10,NDUFS7,MRPS11,SLC25A20,NDUFV1,PI4KB,TRIAP1,PMPCA,SHMT2,ALDH18A1,MRPL21,COQ3,TOMM34,SLC25A1,NIPSNAP1,TIMM8B,BDNF,TMEM126B,ABCF2,TMEM126A,BCS1L,MRPS10,EXOG,RHOT2,GUF1,CYB5B,CPT1A,C19orf70,CHCHD6,MRPL36,ANXA1,MFN2,CAT,ETFDH,TRAP1,COQ9,SURF1,HK2,SLC25A19,NDUFAF5,NDUFS5,GPAM,PGAM5,UQCC1,CPT1C |
| 1.007e-03 | -6.90 | negative regulation of proteasomal protein catabolic process | biological process | GO:1901799 | 64 | 18 | 16441 | 2138 |
UBXN1,OPHN1,TEX14,CSNK2A1,PSMF1,MAD2L2,UBE2E1,KLHL22,ANAPC1,CDC16,SMARCC1,WAC,ANAPC11,ANAPC10,MAD1L1,ATM,FHIT,ANAPC4 |
| 1.009e-03 | -6.90 | REACTOME_METABOLISM_OF_NUCLEOTIDES | MSigDB lists | REACTOME_METABOLISM_OF_NUCLEOTIDES | 70 | 19 | 17758 | 2279 |
AK2,PPAT,UPP1,ADSL,APRT,IMPDH2,CAT,CAD,AMPD3,HPRT1,GART,NME1-NME2,ATIC,NT5C,UMPS,CMPK1,NT5M,ADK,NT5E |
| 1.012e-03 | -6.90 | ribonucleoprotein complex binding | molecular function | GO:0043021 | 79 | 21 | 16491 | 2164 |
PRPF31,MTIF2,HSPA5,OLA1,MRRF,EIF2A,ABCF1,SBDS,PHF6,PES1,DDX3X,NVL,ERI1,SRP68,EEFSEC,PQBP1,EIF2S1,ETF1,PRMT5,NMD3,TIMM50 |
| 1.012e-03 | -6.90 | central_nervous_system-thalamus-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-astrocytoma_Grade_III | 40 | 13 | 17775 | 2278 |
FLNC,BRAF,NF1,ATRX,VPS13D,MYH9,BCOR,MDN1,KMT2C,LYRM2,KIAA1549,CTIF,TNRC6A |
| 1.013e-03 | -6.90 | CAGGTG_V$E12_Q6 | MSigDB lists | CAGGTG_V$E12_Q6 | 2354 | 350 | 17758 | 2279 |
ARHGAP26,GNB3,CDCP1,PRKCSH,TNFRSF21,MKS1,CACNA1H,SBF2,CHAC1,CCNL2,LPAR3,PABPC4,NOS1AP,PCDH7,TOM1L1,PDZD2,SREBF2,ZFHX3,IKZF5,CHD2,TBC1D8,DPF3,HMBOX1,NR6A1,ENHO,LIMA1,EYA3,AKAP12,SEMA3F,DENND4A,PLCXD2,SKIL,DDAH2,SUPT4H1,SH3RF1,ARL6IP5,TMEM139,MPV17,FIS1,RUNX1,FIP1L1,SPOCK2,ZNF532,RBP1,MEF2C,PRPF38B,CLDN15,JUP,FAM189B,OPHN1,RSF1,CHD5,SLC1A1,CDC73,MTUS1,TECTA,HR,SLC7A11,TSPAN2,NOVA2,CACNB2,MYC,MFAP2,IGF2BP1,CALN1,CNOT4,AGL,SERBP1,TERF2,BDNF,ALG6,STAG1,KCNQ3,RREB1,PRDM16,RAP1GAP2,EIF4A2,RAPGEF4,RDH10,ZNF512B,ARID1A,SNAP25,PLCB1,TRIM37,USP46,NCDN,PHF6,DAGLA,SERF2,RPL28,PMEPA1,HIF1A,CDK9,VCAN,CCDC85B,SQLE,NCOR1,MB21D2,GALE,SPRED2,TRERF1,NPAS2,ZBTB37,OLA1,KLHL18,AP1B1,LCLAT1,PDE3A,IGSF1,FLNB,RING1,PHC2,ZNF827,ESAM,TMEM184A,SLX4,ABCA12,UCHL5,FMNL1,VGF,CLCN6,NBEA,WDPCP,GNL1,KCNH3,DSP,POLG2,TTC28,ERC1,SNCA,SLC39A14,VDR,NSMCE2,POLR3E,HOXA3,RPS6KB1,TROVE2,LAMA5,MID1,ANKS1A,MAPT,SSH2,SCAMP3,B4GALT5,TRAK1,RTN4,JMJD6,IP6K2,PSMF1,GIGYF2,RSRC1,ATXN7L1,RGS17,NEBL,ACOT11,CELF1,S100A14,MAP3K14,ERRFI1,ZNF710,DIS3L2,SPTAN1,FAM98A,FGF9,LSM12,POLK,KCNMA1,FRA10AC1,IL6R,ZNF467,STX1A,PTPN4,ATM,BMP4,ADK,RABEP1,CORO2B,SLC43A1,SRM,LETM1,BCAS4,PPARGC1B,GIT2,WNT2B,PCYOX1L,ABL2,RTN1,DST,ARHGAP18,JAZF1,NCKIPSD,GPR87,METTL8,ZEB1,JOSD1,KIAA0922,SLC25A23,ETV1,YARS,PTPRK,LAMA4,FLNC,DTNB,TXLNG,ANK2,ATOX1,ARRDC3,COL4A3BP,SOX4,KCNH2,KRTCAP2,ODC1,SERGEF,ST3GAL5,KIF16B,YTHDF2,CXADR,PAF1,UBTF,TP53BP1,PER1,ARL4A,MKL2,DLX2,MAGI1,USP15,RELL2,TTN,ITFG1,RHOBTB1,PAX2,C16orf52,PRSS3,HES6,TRIM15,ZFP36L1,BARX2,ZIC2,EVPL,DOPEY1,ELL,MCAM,BUD31,NDRG4,WNT16,ATP6V0D1,WARS2,TSTA3,JMJD1C,XPO5,WBSCR22,WWC1,PRDM1,SYT1,UBE2E1,EXOC6,ATAD5,SPAG9,SYNCRIP,KIAA0355,FDPS,DNAH17,TBPL1,FNBP1L,ZNF706,DLL4,CYLD,ID1,OLFM2,SLC48A1,OSBPL9,PPP2R2A,SSBP2,DENND3,RPAIN,SEMA6A,NRF1,BRE,JAG1,CAMTA2,CORO1A,AHCYL1,MOSPD1,HN1,KDM3B,RTN4RL2,KIRREL2,C1QTNF1,GRHL3,R3HDM1,POU2F1,ATXN1,NLN,SLC35F2,ATP8B2,ARL5B,S100A16,BTBD11,SMAD3,SLC30A3,ADNP,KLF4,ITGA2,HSPB8,INTS9,FKBP5,SMG1,ATXN7L2,UNC13D,KLHL24,MINK1,ESCO1,SUPT6H,CMTM8,PDE4B,ARFIP2,IGF2BP2,BMP6,FAM49A,PIP4K2A,BZW2,IQGAP2,MAN1A1,PRKCH,DSG2,STC2,GREB1,CLDND1,TTC17,LDLRAD3,AMOT,PPP1R9B,IL11RA,AP4S1,ZNF821,CRIM1,PPP1R21,PSMC3IP,ARHGEF12,RANGAP1,ARHGAP32,PDE2A,PALLD,POLR3G,CDH24,CSRNP1,RBM26,RBPJ,ITGB4,MMP16 |
| 1.018e-03 | -6.89 | JIANG_VHL_TARGETS | MSigDB lists | JIANG_VHL_TARGETS | 131 | 30 | 17758 | 2279 |
PEA15,GATAD2B,SLC3A2,TSTA3,SIRT6,EIF4A2,CERS5,GMFB,COTL1,SPATS2L,CMTM3,PES1,FBXL5,C1orf159,PRKCH,DNTTIP1,INF2,AHNAK,SPG21,DNAJC1,SET,HIRIP3,VAPB,RNF130,ERRFI1,SGSM3,SERBP1,LRCH1,NIPSNAP1,MTHFD1 |
| 1.019e-03 | -6.89 | RNA polymerase | KEGG pathways | hsa03020 | 31 | 11 | 6908 | 881 |
POLR3D,POLR1A,POLR3E,POLR3B,POLR1B,POLR1C,ZNRD1,POLR1E,POLR3A,POLR2A,POLR3G |
| 1.019e-03 | -6.89 | RNA polymerase | KEGG pathways | ko03020 | 31 | 11 | 6908 | 881 |
POLR3D,POLR1A,POLR3E,POLR3B,POLR1B,POLR1C,ZNRD1,POLR1E,POLR2A,POLR3A,POLR3G |
| 1.021e-03 | -6.89 | cellular response to transforming growth factor beta stimulus | biological process | GO:0071560 | 176 | 38 | 16441 | 2138 |
CGN,NCOR2,ID1,SMAD7,TGFB2,TGFBR2,PDCD5,PDE3A,SKI,FKBP1A,SNW1,MYC,UCHL5,RNF111,SOX6,PTPRK,PXN,GCNT2,FERMT2,CAV1,PTK2,MEN1,PDE2A,UBC,SKIL,SMAD3,CCNT1,PMEPA1,E2F4,HIPK2,CDK9,ADAM9,APAF1,NCOR1,RUNX1,PARD3,MEF2C,USP15 |
| 1.026e-03 | -6.88 | GENTILE_UV_RESPONSE_CLUSTER_D2 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D2 | 40 | 13 | 17758 | 2279 |
BDNF,PCGF3,PHF3,ID1,ZBED4,PDE4B,SMAD7,ID2,SATB2,PNN,RUNX1,NRIP1,MAT2A |
| 1.026e-03 | -6.88 | TRANSLATION_REGULATOR_ACTIVITY | MSigDB lists | TRANSLATION_REGULATOR_ACTIVITY | 40 | 13 | 17758 | 2279 |
GTF2H3,EIF2S2,EIF3C,COPS5,EIF3J,EIF4A2,EIF2S1,EIF2A,EIF2B3,ABCF1,PABPC1,SAMD4A,PAIP2 |
| 1.026e-03 | -6.88 | GCM_SIRT2 | MSigDB lists | GCM_SIRT2 | 40 | 13 | 17758 | 2279 |
DYNC1H1,SNX27,TNK2,MYO10,PREX1,MAPK8IP3,GLTP,RTN4,SIRT2,ZNF710,PEAK1,MFN2,MTUS1 |
| 1.026e-03 | -6.88 | PRKRA (protein kinase, interferon-inducible double stranded RNA dependent activator) | protein interactions | 8575 | 50 | 16 | 16036 | 2270 |
SIRT7,AGO2,CEP126,ZNF346,DDX50,SYNCRIP,SHC1,NOP16,CEBPZ,CCDC124,IGF2BP1,NOC3L,COPS6,BMI1,ZMAT3,RABEPK |
| 1.031e-03 | -6.88 | ribonucleoprotein complex assembly | biological process | GO:0022618 | 188 | 40 | 16441 | 2138 |
SART1,SHQ1,EIF3C,PRPF31,AGO2,SF3A3,NOL3,PRPF39,MBNL1,SBDS,EDC3,DENR,MRPS11,ZNHIT6,ATXN2,CELF1,GEMIN4,PRMT5,SRPK2,PRPF19,SF3A1,SCAF11,DDX28,PTBP2,EIF3J,BMS1,EIF2A,EIF3H,CLNS1A,DDX3X,DYNC1H1,GEMIN5,TSR1,BICD1,LSM14A,LUC7L3,NCBP2,MDN1,NOCT,AGO3 |
| 1.044e-03 | -6.86 | FAF1 (Fas (TNFRSF6) associated factor 1) | protein interactions | 11124 | 104 | 27 | 16036 | 2270 |
CARS,SIRT6,UROD,HSD17B10,RAP1B,CSNK2A1,WDR26,XPO7,UBR4,CDC73,UBC,ANXA1,SKIL,KLHL22,RAP1A,GART,ANXA7,UBR1,HIF1A,SET,IKBKB,CUL2,HIRIP3,VAPB,TROVE2,PRMT3,CARM1 |
| 1.049e-03 | -6.86 | negative regulation of mitotic metaphase/anaphase transition | biological process | GO:0045841 | 35 | 12 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 1.049e-03 | -6.86 | mitotic spindle checkpoint | biological process | GO:0071174 | 35 | 12 | 16441 | 2138 |
KLHL22,ANAPC1,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,ATM,CSNK2A1,MAD2L2,UBE2E1,ANAPC4 |
| 1.050e-03 | -6.86 | nucleobase biosynthetic process | biological process | GO:0046112 | 18 | 8 | 16441 | 2138 |
CAD,HPRT1,GART,PPAT,APRT,UMPS,CMPK1,PRPS1 |
| 1.052e-03 | -6.86 | RNA methyltransferase activity | molecular function | GO:0008173 | 44 | 14 | 16491 | 2164 |
METTL16,METTL1,TRMT5,RNMT,TRMT13,TRMU,ALKBH8,METTL2A,FTSJ1,METTL15,TRMT2A,FBL,FTSJ3,METTL2B |
| 1.062e-03 | -6.85 | KRAS (Kirsten rat sarcoma viral oncogene homolog) | protein interactions | 3845 | 405 | 80 | 16036 | 2270 |
DNM3,FEZ2,EIF3C,KMT2E,NF1,OSBPL9,RCHY1,TMEM177,ZC3H13,NOP56,ANAPC1,BCAS2,KDM2A,COPS4,ANAPC10,POLR3B,PNPLA4,KMT2A,CARM1,TBC1D8,KDM3B,WDR36,GON4L,NOL8,HSD3B7,ARPC3,UBTF,DNTTIP1,CDC16,HSDL2,GATA6,ARL4A,COPS5,DNAJA3,MID1,TRIM36,EFNB2,NBR2,SH2D3A,TTC27,TAF1,PRPF31,WDR37,IKBKAP,NOL3,RLF,CDC73,PIP4K2A,MFHAS1,ARID1B,RNF40,CHN1,C6orf48,SNW1,SUV39H2,DCTN4,KDELC1,CCDC112,ANXA5,EXOSC4,FBL,NAV3,TTPAL,KDM5B,POLA1,ZC3H18,RAP1GDS1,WWC1,RSBN1,EPRS,IREB2,DDX50,ALKBH3,SNAP23,SDCCAG8,CSRNP1,FNTB,SVIL,NAPA,ANAPC4 |
| 1.064e-03 | -6.85 | NIFK (nucleolar protein interacting with the FHA domain of MKI67) | protein interactions | 84365 | 141 | 34 | 16036 | 2270 |
NIFK,CUL7,LIN28B,DDX18,SIRT7,RSL1D1,RBM19,NLE1,HIST2H2AB,NOP56,DHX37,SCAF1,PAK1IP1,DDX31,RNF2,FBL,FTSJ3,ADARB1,SNU13,WDR36,DDX24,GNL3,BMS1,DKC1,RBM28,NOP58,PUM3,POP1,PES1,TOE1,MYBBP1A,SRP68,ZBTB11,SRP14 |
| 1.064e-03 | -6.85 | TGCACTG,MIR-148A,MIR-152,MIR-148B | MSigDB lists | TGCACTG,MIR-148A,MIR-152,MIR-148B | 290 | 56 | 17758 | 2279 |
EFNB2,SNX27,PHF3,TRPM2,PAPD4,B4GALT5,PDK4,SIRT7,KIAA0232,SLC2A1,NHS,KLHL18,SLC25A44,RPS6KA5,SYNJ1,CHD7,SLC7A11,HAS3,UBR1,PRICKLE2,TNPO3,ERRFI1,CNOT4,FBXL19,MOSPD1,SCAF11,CHD9,GPM6A,BAZ2A,TEAD1,PTPRM,ANK2,GPCPD1,ARRDC3,ZBED4,GMFB,ATXN1,PHACTR2,ARHGEF12,SYT1,BTBD11,MLLT10,DYRK1B,EPN2,ARHGAP21,GADD45A,NME7,LSM14A,KLF4,TAF4,CNOT6,NRP1,DOCK6,C18orf25,TNRC6A,NR2C2AP |
| 1.068e-03 | -6.84 | HER-positive_carcinoma | COSMIC cancer mutations | HER-positive_carcinoma | 2074 | 311 | 17775 | 2278 |
ARHGAP26,MYCBP2,POLB,THOC5,PRKAB2,HLTF,PRKCA,LPAR3,UBR5,GIPR,EXOC1,PDZD2,PMAIP1,MAD1L1,FTSJ3,CDK6,NRAS,ABCC2,PLEKHM3,SH3GL1,SPOP,BRCA2,TRRAP,RAD18,SH3RF1,VPS13D,XPNPEP1,DIRAS1,DNAH2,RUNX1,CCNB1IP1,NRP1,FIP1L1,ZNF598,ZNF532,LPP,MEF2C,CARS,EP400,DROSHA,CELSR1,ANKRD17,PRPF31,NHS,PIK3R4,TGFBR2,CDC73,PRKCE,C6orf48,UBE3A,USPL1,ATIC,MYC,VWDE,GTF3C3,GEMIN4,ANGPT2,GATAD2B,PEA15,SIK3,GTF2H3,IFRD1,PRDM16,POLA1,RAP1B,USP10,IMPDH2,ARID1A,TRIM37,USP46,IRS1,DYNC1H1,ZNF425,ASCC3,VPS13C,SQLE,NCOR1,MAP2K4,SPRED2,ABCA3,BIRC6,DDR2,FOSL2,LTB4R,FLNB,DECR1,SLX4,SHC1,KDM2A,ABCA12,UCHL5,SOCS6,MRPS27,TTC3,GSTA4,MSH4,KMT2A,PLEKHA4,ZC3H3,CDK12,PMS1,RFC4,BRD4,GON4L,PDK1,STAMBP,MARCH6,MEF2D,MEGF11,STK10,ERC1,FGFR1,ASTN2,ARL13B,HOXA3,ACP1,RPS6KB1,TRAF3,FUS,MDN1,KLHDC4,BRCC3,MID1,TRIM36,BRAF,XPC,TCF3,KIF5C,MLH1,TGFB2,GIGYF2,FOXO3,POM121,MAD2L2,NEDD4,ABL1,UNC13A,LTN1,ANXA5,FBXL19,DIS3L2,FGF9,PXN,APEX1,WDFY3,ZC4H2,FZD3,KCNMA1,KLF6,CCDC150,NSD1,HERC1,ATM,SLC25A19,BMP4,RABEP1,DDIT3,STK4,PHF3,FEM1C,NF1,GPBP1L1,PTPRA,MFGE8,HECTD3,CSNK2A1,BIRC2,CUTC,MAP2K3,SMARCB1,WNT2B,ABL2,RAP1A,JAZF1,SLC39A7,NCKIPSD,ANAPC11,XRCC2,RELB,JOSD1,KIAA0922,B3GNTL1,RAN,ZMYM2,ETV1,OGG1,CARM1,PRKACB,CDC37,DBN1,LAMA4,RBCK1,PPARG,CDK4,KSR2,BRCA1,CAV1,SGK2,KMT2C,MLLT10,RHOU,GLS,TMCO1,TCF7L1,SUFU,PER1,MKL2,SOCS4,TNFRSF1A,RAD51B,CSMD3,COPS6,MAGI1,USP15,FBXO45,AOC3,FOXO1,SEC24D,MAPK8IP3,LAMTOR3,PCSK7,QSER1,SPIRE1,ELL,GTF2H1,CTR9,WNT16,N4BP2,MSI2,TRAPPC9,PDE4A,USP49,TLE3,LIG4,PRDM1,TCF7L2,SPAG9,FAM135A,ITPRIPL1,BICD1,SYNCRIP,PALB2,INTS5,HK2,ARHGAP12,DDX10,PRKAR2A,USP7,DMXL2,TCF12,DLL4,CYLD,PCNT,NTSR1,PBX1,RIPK1,PPP2R2A,RADIL,SBDS,JAG1,SOCS1,UBR1,IKBKB,RNF2,MET,CASP10,MAML3,TEX19,PARP2,MRRF,TMEM123,NUP214,USP36,EIF3H,WARS,EXO1,RANBP2,RBBP8,COPS5,CEBPZ,HEATR1,NFASC,SEPT5,USP11,MUTYH,SMG1,BCKDK,CSNK1A1,POGZ,GFM2,TOP1,RPS6KB2,DNMBP,ADAMTSL3,FGF2,TEAD1,TEX14,RAP1GDS1,ARHGEF12,MEN1,PIK3CB,DKK1,ZRANB3,SRBD1,AGTPBP1,SET,MSH3,DNAJC12,USP20,RBPJ,NFKBIB |
| 1.068e-03 | -6.84 | breast-carcinoma-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-HER-positive_carcinoma | 2074 | 311 | 17775 | 2278 |
ARHGAP26,MYCBP2,POLB,THOC5,PRKAB2,HLTF,PRKCA,LPAR3,UBR5,GIPR,EXOC1,PDZD2,PMAIP1,MAD1L1,FTSJ3,CDK6,NRAS,ABCC2,PLEKHM3,SH3GL1,SPOP,BRCA2,TRRAP,RAD18,SH3RF1,VPS13D,XPNPEP1,DIRAS1,DNAH2,RUNX1,CCNB1IP1,NRP1,FIP1L1,ZNF598,ZNF532,LPP,MEF2C,CARS,EP400,DROSHA,CELSR1,ANKRD17,PRPF31,NHS,PIK3R4,TGFBR2,CDC73,PRKCE,C6orf48,UBE3A,USPL1,ATIC,MYC,VWDE,GTF3C3,GEMIN4,ANGPT2,GATAD2B,PEA15,SIK3,GTF2H3,IFRD1,PRDM16,POLA1,RAP1B,USP10,IMPDH2,ARID1A,TRIM37,USP46,IRS1,DYNC1H1,ZNF425,ASCC3,VPS13C,SQLE,NCOR1,MAP2K4,SPRED2,ABCA3,BIRC6,DDR2,FOSL2,LTB4R,FLNB,DECR1,SLX4,SHC1,KDM2A,ABCA12,UCHL5,SOCS6,MRPS27,TTC3,GSTA4,MSH4,KMT2A,PLEKHA4,ZC3H3,CDK12,PMS1,RFC4,BRD4,GON4L,PDK1,STAMBP,MARCH6,MEF2D,MEGF11,STK10,ERC1,FGFR1,ASTN2,ARL13B,HOXA3,ACP1,RPS6KB1,TRAF3,FUS,MDN1,KLHDC4,BRCC3,MID1,TRIM36,BRAF,XPC,TCF3,KIF5C,MLH1,TGFB2,GIGYF2,FOXO3,POM121,MAD2L2,NEDD4,ABL1,UNC13A,LTN1,ANXA5,FBXL19,DIS3L2,FGF9,PXN,APEX1,WDFY3,ZC4H2,FZD3,KCNMA1,KLF6,CCDC150,NSD1,HERC1,ATM,SLC25A19,BMP4,RABEP1,DDIT3,STK4,PHF3,FEM1C,NF1,GPBP1L1,PTPRA,MFGE8,HECTD3,CSNK2A1,BIRC2,CUTC,MAP2K3,SMARCB1,WNT2B,ABL2,RAP1A,JAZF1,SLC39A7,NCKIPSD,ANAPC11,XRCC2,RELB,JOSD1,KIAA0922,B3GNTL1,RAN,ZMYM2,ETV1,OGG1,CARM1,PRKACB,CDC37,DBN1,LAMA4,RBCK1,PPARG,CDK4,KSR2,BRCA1,CAV1,SGK2,KMT2C,MLLT10,RHOU,GLS,TMCO1,TCF7L1,SUFU,PER1,MKL2,SOCS4,TNFRSF1A,RAD51B,CSMD3,COPS6,MAGI1,USP15,FBXO45,AOC3,FOXO1,SEC24D,MAPK8IP3,LAMTOR3,PCSK7,QSER1,SPIRE1,ELL,GTF2H1,CTR9,WNT16,N4BP2,MSI2,TRAPPC9,PDE4A,USP49,TLE3,LIG4,PRDM1,TCF7L2,SPAG9,FAM135A,ITPRIPL1,BICD1,SYNCRIP,PALB2,INTS5,HK2,ARHGAP12,DDX10,PRKAR2A,USP7,DMXL2,TCF12,DLL4,CYLD,PCNT,NTSR1,PBX1,RIPK1,PPP2R2A,RADIL,SBDS,JAG1,SOCS1,UBR1,IKBKB,RNF2,MET,CASP10,MAML3,TEX19,PARP2,MRRF,TMEM123,NUP214,USP36,EIF3H,WARS,EXO1,RANBP2,RBBP8,COPS5,CEBPZ,HEATR1,NFASC,SEPT5,USP11,MUTYH,SMG1,BCKDK,CSNK1A1,POGZ,GFM2,TOP1,RPS6KB2,DNMBP,ADAMTSL3,FGF2,TEAD1,TEX14,RAP1GDS1,ARHGEF12,MEN1,PIK3CB,DKK1,ZRANB3,SRBD1,AGTPBP1,SET,MSH3,DNAJC12,USP20,RBPJ,NFKBIB |
| 1.073e-03 | -6.84 | pancreas-carcinoid-endocrine_tumour-islet_cell | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-islet_cell | 155 | 34 | 17775 | 2278 |
RTTN,BRAF,NF1,ATRX,SLC6A8,ENOX1,ABCA7,DDIT4,ARMC5,MYC,MET,CEP135,ITGAX,SLC25A23,PLEKHG4,C21orf58,NRAS,ATP6V0A1,MEN1,SUPT5H,FGFR1,IRS1,PAF1,DYNC1H1,ZDHHC11,AHNAK,ZZEF1,ZNF557,ATM,PRPF4,MAGI1,IGBP1,MAP2K4,SMG1 |
| 1.073e-03 | -6.84 | islet_cell | COSMIC cancer mutations | islet_cell | 155 | 34 | 17775 | 2278 |
RTTN,BRAF,NF1,ATRX,SLC6A8,ENOX1,ABCA7,DDIT4,MYC,ARMC5,CEP135,MET,ITGAX,SLC25A23,PLEKHG4,C21orf58,NRAS,ATP6V0A1,MEN1,SUPT5H,FGFR1,IRS1,DYNC1H1,PAF1,ZDHHC11,AHNAK,ZNF557,ZZEF1,ATM,PRPF4,MAGI1,IGBP1,MAP2K4,SMG1 |
| 1.086e-03 | -6.83 | REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX | MSigDB lists | REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX | 60 | 17 | 17758 | 2279 |
NCOR2,CGN,SMAD7,MEN1,TGFBR2,SKI,SMAD3,SKIL,FKBP1A,CCNT1,PMEPA1,E2F4,MYC,CDK9,UCHL5,NCOR1,PARD3 |
| 1.086e-03 | -6.82 | Metabolism of nucleotides | REACTOME pathways | R-HSA-15869 | 82 | 22 | 8202 | 1117 |
AK2,PPAT,ITPA,UPP1,ADSL,APRT,IMPDH2,NT5C3A,NUDT15,CAT,CAD,AMPD3,HPRT1,GART,NME1-NME2,ATIC,NT5C,UMPS,CMPK1,ADK,NT5M,NT5E |
| 1.098e-03 | -6.81 | core promoter binding | molecular function | GO:0001047 | 146 | 33 | 16491 | 2164 |
HMGA2,EGR1,NPAS2,AGO2,SMARCA4,FOXO3,SMARCB1,RRN3,NRF1,ZFHX3,RELB,CHD2,PRMT5,NRIP1,KMT2A,TOP1,ATF4,RREB1,BAZ2A,PPARG,PSPC1,SOX4,TCF7L2,UBTF,NSD1,MYBBP1A,GADD45A,GATA6,KLF4,ARNTL,RUNX1,RBPJ,SMYD3 |
| 1.099e-03 | -6.81 | ACCATTT,MIR-522 | MSigDB lists | ACCATTT,MIR-522 | 155 | 34 | 17758 | 2279 |
MYCBP2,TTN,FEM1C,ATRX,ARID2,NHS,WDR26,PRPF39,CSNK1A1,FOXP1,MBNL1,RPGRIP1L,UBE3A,JOSD1,RNF2,CMPK1,ETV1,PERP,HNRNPM,TOP1,TBC1D8,STAG1,CRIM1,EHMT1,ARID5B,RSBN1,EIF2A,MEF2D,ENC1,LRP1B,SYNCRIP,KIAA0355,ZRANB2,ZNF532 |
| 1.100e-03 | -6.81 | peptide biosynthetic process | biological process | GO:0043043 | 395 | 73 | 16441 | 2138 |
GGT1,EIF3C,RARS2,AARS2,MRPL10,RPS29,AARS,PABPC4,DENR,MRPS30,SRPRB,FARSA,MMP7,RPS16,MRPS27,ETF1,YARS,NARS2,GARS,EIF4E3,NARS,HARS,EIF3J,MTIF2,MRRF,EIF3H,WARS,DDX3X,EEFSEC,COPS5,BDH2,FTSJ1,EIF2B3,CARS,SARS,LARS2,AGO2,FARS2,VARS,SSR4,GFM2,YARS2,IGF2BP3,MRPS11,EIF2S2,GATC,SELT,HARS2,MRPL21,PPA1,PABPC1,RPL22L1,RPS6KB2,GTF2H3,WARS2,EIF4A2,MRPS10,MARS,EIF2A,GUF1,EIF5B,ABCF1,TARS,MRPL36,EPRS,RARS,RPL28,SRP68,EIF2S1,CDKAL1,GGT7,CNDP2,SRP14 |
| 1.100e-03 | -6.81 | protein methylation | biological process | GO:0006479 | 113 | 27 | 16441 | 2138 |
KMT2D,ASH1L,SETD1B,WDR61,BAZ2A,KMT2E,EHMT1,SETD2,PCMT1,SETD7,KMT2C,MEN1,CHD5,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,CTR9,ETF1,PRMT5,FBL,KMT2A,SETD6,SMYD3,PRMT3,CARM1 |
| 1.100e-03 | -6.81 | protein alkylation | biological process | GO:0008213 | 113 | 27 | 16441 | 2138 |
KMT2D,ASH1L,SETD1B,WDR61,BAZ2A,KMT2E,EHMT1,SETD2,PCMT1,SETD7,KMT2C,MEN1,CHD5,DOT1L,NSD1,EHMT2,SUV39H2,CAMKMT,CTR9,ETF1,PRMT5,FBL,KMT2A,SETD6,SMYD3,PRMT3,CARM1 |
| 1.105e-03 | -6.81 | GSE3982_NEUTROPHIL_VS_TH2_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH2_DN | 191 | 40 | 17758 | 2279 |
EP400,NDUFA5,PCNT,KIF5C,VARS,RCAN1,TUBB6,LYRM2,MGA,LPIN1,DST,CTNNBL1,MYC,BANF1,ANP32B,NOC3L,POLE3,ERI3,MTHFD1,NAA38,TIMM8B,ZNF195,GLTSCR2,HOMER2,ABCF2,KIF15,C11orf49,RANGAP1,BRCA1,SLC35D1,ODC1,PES1,RARS,RBBP8,POLR3E,CUL2,HSPB8,GPN1,PPP3CC,MORC2 |
| 1.105e-03 | -6.81 | GSE27786_NEUTROPHIL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_NEUTROPHIL_VS_MONO_MAC_DN | 191 | 40 | 17758 | 2279 |
WDR75,IFT57,PRKCSH,FAM189B,TRAK1,LETMD1,AARS,PELP1,MCM9,FDX1,NOP56,C6orf48,ACD,ZNF326,DTNBP1,PRICKLE2,SUCLG2,SHMT2,CEP135,HRG,LDLRAD3,MTHFD1,TSHZ1,MSI2,RFC4,PSAT1,GINS3,POLK,EIF3J,ANKMY2,BMS1,BRCA1,SLC7A1,BRCA2,RPL28,DUS3L,LRRC40,ZAK,SPOCK2,PRKAR2A |
| 1.111e-03 | -6.80 | GSE3982_MAST_CELL_VS_MAC_UP | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_UP | 185 | 39 | 17758 | 2279 |
WDR74,CLK1,SLK,HSD17B10,SEMA3E,ABHD6,NLE1,CD226,URB1,IGF2BP3,SRPRB,NPRL2,SNW1,CTR9,GSTA4,ALDH18A1,LRRC20,IFRD1,FBXW4,DNMBP,WDR61,APEX1,TSPYL4,POLA1,CDK4,TRA2A,TLE3,PCMT1,RERE,ZNF155,HERC1,SET,DNAH17,RBM26,MED20,WDR33,TROVE2,SMYD3,MUTYH |
| 1.113e-03 | -6.80 | nuclease activity | molecular function | GO:0004518 | 199 | 42 | 16491 | 2164 |
HMGA2,DROSHA,AGO2,TATDN3,FAN1,MAP1S,ISG20L2,POP5,RNASEH2B,PARN,EDC3,RPP30,SLX4,ERI1,APLF,XRCC2,EXOSC4,CPSF3,ERI3,N4BP2,OGG1,DIS3L2,EXOSC2,APEX1,POLA1,TSN,APTX,EXOG,ZRANB3,ZC3H12A,EXO1,POP1,TOE1,RBBP8,RAD51B,ALKBH1,AEN,CNOT6,EME1,TATDN1,TSEN2,NOCT |
| 1.115e-03 | -6.80 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN | 179 | 38 | 17758 | 2279 |
CARS,CHMP2A,BCKDK,PIGM,INSIG2,RIBC2,DYM,DCP1B,CSNK2A1,RMI1,BZW2,UBL5,MAD2L2,ETFB,FAM192A,PPID,CBR4,MPST,TPM4,WDHD1,METTL15,CYB5B,UBE2K,PLIN2,EXO1,HPRT1,ATAD5,MTHFD2,SSU72,TRAP1,TP53BP1,DNAJA3,PAM,ATG7,FNTB,UMPS,MED20,FAHD1 |
| 1.120e-03 | -6.79 | RNA-dependent ATPase activity | molecular function | GO:0008186 | 64 | 18 | 16491 | 2164 |
SKIV2L,DDX28,DDX41,DDX24,DDX18,DDX19A,EIF4A2,DHX34,DDX49,DHX35,DHX57,DDX3X,DDX56,DDX50,DHX37,DHX33,DDX31,DDX10 |
| 1.120e-03 | -6.79 | ATP-dependent RNA helicase activity | molecular function | GO:0004004 | 64 | 18 | 16491 | 2164 |
SKIV2L,DDX28,DDX41,DDX24,DDX18,DDX19A,EIF4A2,DHX34,DDX49,DHX35,DHX57,DDX3X,DDX56,DDX50,DHX37,DHX33,DDX31,DDX10 |
| 1.121e-03 | -6.79 | GTF2A1 (general transcription factor IIA 1) | protein interactions | 2957 | 55 | 17 | 16036 | 2270 |
PTCD2,SARS,GARS,KDM5B,TAF1,CSNK2A1,MKX,TASP1,TAF4,TBPL1,ATG7,ZEB1,SHMT2,ME1,RDX,BLMH,TERF2 |
| 1.128e-03 | -6.79 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma) | protein interactions | 7532 | 370 | 74 | 16036 | 2270 |
CGN,MYCBP2,CUL7,PAFAH1B1,PRKCA,LTB4R,GBF1,GIT2,HSPA1A,PABPC4,EDC3,MIEF1,CAD,ZBTB21,PPFIBP1,NCKIPSD,RMDN3,CPSF3,VCL,SRRM2,PRPF19,PHLDB2,SSFA2,LIMA1,VIM,PNN,AKAP13,DENND4A,SON,ERC1,CHAF1A,EXO1,EPN2,G6PD,LUC7L3,COPS5,NOLC1,CEP170,ANKS1A,SYNPO,PTPN14,PARD3,PRPF38B,BRAF,FOXO1,FN1,CLK1,KLC4,KIF5C,PLA2G12A,AKT1S1,CLINT1,FOXO3,ABL1,PI4KB,MCM5,PRMT5,AMOT,PABPC1,SAMD4A,HNRNPM,CLK2,TRA2A,WWC1,MEX3B,UBC,PGD,DYNC1H1,IRS1,SVIL,PGAM5,ZAK,RABEP1,KIF1B |
| 1.134e-03 | -6.78 | regulation of mitotic cell cycle phase transition | biological process | GO:1901990 | 256 | 51 | 16441 | 2138 |
HMGA2,CUL4A,ANKRD17,XPC,TCF3,PLRG1,CSNK2A1,SMARCA4,PBX1,ID2,PID1,PPP1R1C,SIRT2,RNASEH2B,GIGYF2,CDC73,PSMF1,MAD2L2,ANAPC1,NEK6,ANAPC11,TRIAP1,ANAPC10,MAD1L1,RDX,FBXO31,LSM10,CTC1,PPP1R9B,BRD4,CRADD,FOXN3,CDK4,TEX14,SMARCD3,PSMA1,TPRA1,SOX4,PLCB1,UBC,UBE2E1,ZNF655,ANXA1,DDX3X,CAMK2D,KLHL22,CDC16,NSMCE2,RAD51B,ATM,ANAPC4 |
| 1.146e-03 | -6.77 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | 355 | 66 | 17758 | 2279 |
CDCP1,LUZP1,FEM1C,LPCAT2,SLC2A1,KLHL18,TUBB6,HMOX2,LTB4R,ABHD6,PCDH7,KCTD11,ANKRD13A,ZBED2,ABCA12,PERP,HN1,ELOF1,CDC37,SSFA2,LIMA1,UPP1,GRHL3,DSP,RAB10,GNAI1,AHNAK,YIPF2,CC2D1B,FAM114A2,AHNAK2,PAM,GALNT10,WDR66,SYNPO,TSPAN5,USP15,JUP,ITPRIP,DLGAP4,PCSK7,RCAN1,PPP1R1C,CSNK1A1,REEP5,PTRF,SDCBP2,PTGS1,CD44,ATP6V0D1,NT5E,PXN,AGPAT4,LDHA,TPM4,PHACTR2,MAP7D1,PRDM1,ARRDC4,KLF6,OXSR1,RARS,HIF1A,UBAP1,DOCK6,HRH1 |
| 1.146e-03 | -6.77 | OSMAN_BLADDER_CANCER_DN | MSigDB lists | OSMAN_BLADDER_CANCER_DN | 355 | 66 | 17758 | 2279 |
SART1,PHF3,CUL4A,RBM33,SPATA2L,DDX19A,RIPK1,IKBIP,MRPS30,SKI,ABL2,RPS16,FMNL1,RABGAP1L,CHD2,AHCYL1,CDK12,SF3A1,GLTSCR2,GNG7,EFHC1,ATP8B2,FLVCR1,SAP30BP,USP36,SSU72,SMARCC1,MTCH1,EPM2AIP1,CHST11,MAP3K13,C16orf52,DPF2,PPHLN1,IP6K2,SSR4,RPS6KA5,TGFBR2,RHBDD1,SFI1,TOX4,ELL,MLX,GART,NISCH,CELF1,FBL,HNRNPM,DIS3L2,SIK3,AOC2,EIF4A2,EPS15L1,SCFD2,MARS,ARID1A,EIF5B,ARIH2,RERE,RPA1,IREB2,RPL28,SERF2,KIAA0355,SURF1,WDR33 |
| 1.147e-03 | -6.77 | DNA replication | KEGG pathways | hsa03030 | 36 | 12 | 6908 | 881 |
RFC4,MCM6,RFC3,POLE2,PRIM2,POLA1,MCM5,POLE3,SSBP1,MCM2,RNASEH2B,RPA1 |
| 1.147e-03 | -6.77 | DNA replication | KEGG pathways | ko03030 | 36 | 12 | 6908 | 881 |
RFC4,RFC3,MCM6,POLE2,PRIM2,POLA1,MCM5,POLE3,SSBP1,RNASEH2B,MCM2,RPA1 |
| 1.147e-03 | -6.77 | BILD_CTNNB1_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_CTNNB1_ONCOGENIC_SIGNATURE | 76 | 20 | 17758 | 2279 |
SCAF11,CYP24A1,CHD9,ASH1L,LUZP1,ATRX,PHACTR2,URB1,DYNC1H1,EPRS,KDM4B,VCAN,HIPK2,LARP4B,ZMAT3,ZNF532,TRIM14,SMG1,TMCC1,TOP1 |
| 1.151e-03 | -6.77 | POS_RESPONSE_TO_HISTAMINE_DN | MSigDB lists | POS_RESPONSE_TO_HISTAMINE_DN | 11 | 6 | 17758 | 2279 |
KLHL22,EIF2S2,ASNS,NCOR1,TATDN1,METTL22 |
| 1.156e-03 | -6.76 | PABC | prosite domains | PS51309 | 5 | 4 | 11866 | 1504 |
PABPC1L,UBR5,PABPC1,PABPC4 |
| 1.162e-03 | -6.76 | Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | REACTOME pathways | R-HSA-2173793 | 43 | 14 | 8202 | 1117 |
SMAD3,SKIL,SNW1,NCOR2,CCNT1,CDK9,E2F4,MYC,SMAD7,RNF111,NCOR1,MEN1,UBC,SKI |
| 1.163e-03 | -6.76 | MLL1 complex | cellular component | GO:0071339 | 27 | 10 | 17570 | 2233 |
KAT8,PRPF31,KANSL1,TAF1,TAF4,SENP3,RNF2,KMT2A,PELP1,MGA |
| 1.163e-03 | -6.76 | MLL1/2 complex | cellular component | GO:0044665 | 27 | 10 | 17570 | 2233 |
KAT8,PRPF31,KANSL1,TAF1,TAF4,SENP3,RNF2,KMT2A,PELP1,MGA |
| 1.169e-03 | -6.75 | positive transcription elongation factor complex b | cellular component | GO:0008024 | 5 | 4 | 17570 | 2233 |
SNW1,BRD4,CCNT1,CDK9 |
| 1.169e-03 | -6.75 | box C/D snoRNP complex | cellular component | GO:0031428 | 5 | 4 | 17570 | 2233 |
SNU13,FBL,NOP58,NOP56 |
| 1.172e-03 | -6.75 | BCL7B (B-cell CLL/lymphoma 7B) | protein interactions | 9275 | 17 | 8 | 16036 | 2270 |
TERF2IP,DPF3,DPF2,SMARCA4,SMARCD3,ARID1A,ARID1B,SMARCB1 |
| 1.172e-03 | -6.75 | NOL11 (nucleolar protein 11) | protein interactions | 25926 | 17 | 8 | 16036 | 2270 |
PRAME,CUL7,SIRT7,UTP15,VAPB,RNF2,BRCA1,FBL |
| 1.172e-03 | -6.75 | BTBD1 (BTB (POZ) domain containing 1) | protein interactions | 53339 | 17 | 8 | 16036 | 2270 |
C9orf78,COPS4,COPS5,COPS3,UBXN1,COPS6,PNMA1,TOP1 |
| 1.173e-03 | -6.75 | nucleic acid phosphodiester bond hydrolysis | biological process | GO:0090305 | 244 | 49 | 16441 | 2138 |
CUL4A,DROSHA,DCP1B,AGO2,TATDN3,FAN1,ISG20L2,POP5,RNASEH2B,PARN,EDC3,RPP30,ERI1,APLF,GTF2H1,EXOSC4,CPSF3,ERI3,N4BP2,OGG1,DIS3L2,GTF2H3,EXOSC2,RFC4,RFC3,APEX1,POLK,POLA1,TSN,APTX,EXOG,UBC,ZRANB3,RPA1,EXO1,POP1,ZC3H12A,TOE1,KPNA1,RBBP8,AEN,NCBP2,CNOT6,EME1,TSEN2,WDR33,TATDN1,NOCT,AGO3 |
| 1.173e-03 | -6.75 | response to ionizing radiation | biological process | GO:0010212 | 142 | 32 | 16441 | 2138 |
POLB,EGR1,XRRA1,TMEM109,FANCD2,IKBIP,KDM1A,BRE,PMAIP1,INTS7,MYC,XRCC2,SPIDR,CLK2,TRIM13,EYA3,LIG4,CAV1,BRCA1,IL6R,MEN1,ANXA1,BRCA2,GADD45A,ALAD,TP53BP1,RAD51B,H2AFX,ATM,AEN,BRCC3,XRCC4 |
| 1.176e-03 | -6.75 | CD274 (CD274 molecule) | protein interactions | 29126 | 46 | 15 | 16036 | 2270 |
EXOC1,STAG1,THADA,NF1,FAM114A2,PDS5B,TNPO3,ATM,HEATR1,TTI1,XPO7,XPO6,VAC14,COG5,SLC39A11 |
| 1.179e-03 | -6.74 | BROWNE_HCMV_INFECTION_20HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_DN | 98 | 24 | 17758 | 2279 |
CHMP2A,CRADD,FGF2,RHOBTB1,TFPI,TRIO,PDE4B,TRIM22,MBNL1,ECH1,TMCO6,ANXA1,IGF2BP3,DST,TPD52L2,RABGAP1L,SVIL,HMBS,ANXA2,VCL,MGLL,TMEM158,TBC1D8,LPP |
| 1.185e-03 | -6.74 | NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | NUCLEOCYTOPLASMIC_TRANSPORT | 87 | 22 | 17758 | 2279 |
TRIP6,NF1,KHDRBS1,SMG7,ATXN1,XPO7,NUP214,NUP160,NOP58,RPAIN,RERE,SMAD3,RANBP2,MYBBP1A,KPNA1,KPNA3,NUP133,NCKIPSD,NCBP2,UPF2,XPO6,SMG1 |
| 1.186e-03 | -6.74 | DANG_MYC_TARGETS_UP | MSigDB lists | DANG_MYC_TARGETS_UP | 138 | 31 | 17758 | 2279 |
METTL1,SRM,NRAS,EIF3C,APEX1,DDX18,PPAT,GNL3,CDK4,MRPL10,MINA,LDHA,ID2,PSMG1,DKC1,TIMM10,ODC1,MGST1,MAT2A,PYCR1,CAD,RPP30,RPS16,SRSF2,PPID,CEBPZ,EIF2S1,FXN,DDX10,TOP1,MTHFD1 |
| 1.193e-03 | -6.73 | ribose phosphate metabolic process | biological process | GO:0019693 | 332 | 63 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,NDUFB5,PDE4B,OLA1,APRT,CHCHD10,RNASEH2B,COX10,HSPA1A,NDUFS7,PDE3A,NDUFB3,CAD,AMPD3,NDUFV1,GART,ENTPD5,ATP5G2,PDE10A,ATIC,MYH3,PPCDC,CMPK1,NDUFA6,FXN,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,PDE4A,ITPA,PPAT,UPP1,SULT4A1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,PDE2A,PDE3B,PDE8B,ATP5D,STOML2,SNCA,PGD,HSPA1B,HPRT1,NME7,COQ9,G6PD,SURF1,HK2,UMPS,NDUFS5,BPNT1,ADK,PDE9A |
| 1.194e-03 | -6.73 | mitochondrial membrane | cellular component | GO:0031966 | 641 | 108 | 17570 | 2233 |
CYP24A1,IMMP2L,NDUFA5,LETM1,SUCLG1,NDUFAF2,PDK4,MRPL10,NDUFB5,SLC25A21,SLC25A44,SLC9B2,PRKCA,COX10,COA1,AMBRA1,LPIN1,MIEF1,MRPS30,NDUFB3,ABCA12,PMAIP1,ATP5G2,LETM2,MRPS27,RMDN3,ADCK4,NDUFA6,MTHFD2L,SLC25A23,TMEM14C,HTRA2,MPST,TIMM50,ACSL5,GDAP1,SFXN4,CPOX,MCL1,FOXRED1,FLVCR1,MGST1,MPC1,ATP5D,STOML2,SNCA,TIMM44,TAMM41,DDX3X,TIMM17A,PEMT,MPV17,SLC25A11,FIS1,RPS6KB1,CLU,FAHD1,UQCC2,SLC25A26,MTCH1,HERC2,AK2,HSD17B10,SLC25A12,LETMD1,OPA1,TIMM10,NDUFS7,SLC25A20,MRPS11,NDUFV1,PI4KB,PMPCA,SHMT2,ALDH18A1,MRPL21,COQ3,TOMM34,SLC25A1,NIPSNAP1,TIMM8B,BDNF,TMEM126B,TMEM126A,BCS1L,MRPS10,EXOG,GUF1,CPT1A,CYB5B,RHOT2,CHCHD6,C19orf70,MRPL36,ANXA1,MFN2,ETFDH,TRAP1,COQ9,SURF1,HK2,SLC25A19,NDUFAF5,NDUFS5,GPAM,PGAM5,UQCC1,CPT1C |
| 1.199e-03 | -6.73 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | 487 | 86 | 17758 | 2279 |
SART1,ID1,BTBD2,PRKCSH,RBFOX2,PPIL1,TMEM132A,GBF1,PDE3A,SKI,ZFHX3,WAC,UBAP2L,ANKRD11,RNF111,CPSF3,SAP30,FLNC,KDM3B,PHLDB2,CHD9,BRD4,GON4L,LIMA1,EIF3J,CDK4,NOL8,NFIA,FAM171A2,MARCKSL1,SOX4,TBC1D16,CXADR,AHNAK,DNAJC1,CHD3,CTAGE5,NOLC1,ZBTB11,TNRC6A,LPP,DNAJC2,TAF1,TCF3,H2AFJ,PPHLN1,ID2,CSNK1A1,GIGYF2,RSRC1,NEDD4,SNW1,NAV1,DCTN4,WDR60,CLDND1,NLGN3,NRIP1,HMGCR,KDM6B,GTF2H3,CRIM1,FOXN3,ARID5B,WWC1,RANGAP1,MAP7D1,PALLD,PLCB1,SYMPK,PHF6,CAT,MYBBP1A,SAMD5,BAZ2B,DAGLB,L3MBTL3,FSCN1,SET,SENP3,NCOR1,BMP4,PFDN2,PSAP,NR2F2,ARHGAP10 |
| 1.201e-03 | -6.72 | PABP_HYD | interpro domains | IPR002004 | 5 | 4 | 18293 | 2341 |
PABPC1L,UBR5,PABPC1,PABPC4 |
| 1.201e-03 | -6.72 | PRibTrfase_dom | interpro domains | IPR000836 | 5 | 4 | 18293 | 2341 |
UMPS,APRT,HPRT1,PPAT |
| 1.204e-03 | -6.72 | human chr10p12 | chromosome location | human chr10p12 | 6 | 4 | 26250 | 2590 |
NEBL,NRP1,CACNB2,MLLT10 |
| 1.210e-03 | -6.72 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1763 | 271 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,PRKCA,GABPB2,LPIN1,NOS1AP,SKI,GIPR,SREBF2,ZFHX3,WIZ,RNF111,ZNF148,MEIS3,DDN,HMBOX1,NR6A1,GNL3,NFIA,TCEB3,CUX1,AKAP12,SUPT20H,STOML2,DDX3X,DDAH2,BRCA2,SUPT4H1,CCNT1,RUNX1,RFXAP,P2RY11,MEF2C,BANP,EPM2AIP1,EGR1,JUP,KHDRBS1,SIRT7,PID1,RSF1,CDC73,MYC,MED24,PABPC1,MYB,GTF2H3,BDNF,WDR61,STAG1,RREB1,PRDM16,ARID5B,SMARCD3,ARID1A,NELFA,PLCB1,TRIM37,ONECUT2,ABCF1,IRS1,CAT,TASP1,HIF1A,CDK9,SPEN,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SHC1,ACD,WAC,LPIN2,KMT2A,KMT2D,BRD4,SATB2,MED16,MEF2D,SETD7,ERC1,SERP1,SNCA,VDR,TAF2,SMARCC1,HIPK2,PEMT,RPS6KB1,HMGA2,INSIG2,TCF3,ID2,TRIM22,RPS6KA5,FOXO3,MAD2L2,SFR1,TADA3,SNW1,TRIAP1,YBX3,LARP4B,SAMD4A,SOX6,MBTPS2,SLC40A1,IL6R,KLF6,GUF1,FOXC1,UBC,POLR2A,ANXA1,NSD1,ARID3B,BMP4,IGBP1,UQCC1,DDIT3,KAT6A,TRIM16,ATRX,NF1,KMT2E,GPBP1L1,AAMDC,PPARGC1B,SIRT2,MAP2K3,SMARCB1,PHF5A,DHX33,ZEB1,RELB,RAN,ETV1,TRIM14,ZBTB17,DEAF1,TRIM13,ATF4,RBCK1,PPARG,CDK4,HSPA5,BRCA1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,TNFRSF1A,DLX2,CLU,ZC3H8,UQCC2,FOXO1,TAF1,PAX2,SMAD7,TRIM15,ZIC2,BARX2,RLF,ARID1B,NAMPT,SUB1,ELL,CEP290,BUD31,CTR9,GTF2H1,ICE2,NRIP1,CAMKK2,PAXBP1,UTP15,EIF2A,SUPT5H,TCF7L2,ATXN7,IRAK2,ZFP90,TBL1X,TESC,TCF12,ASH1L,NTSR1,RIPK1,PBX1,SMARCA4,PELP1,KDM1A,NRF1,RRN3,JAG1,CAMTA2,NVL,IKBKB,MET,CTC1,MAML3,MOSPD1,KAT8,DDX41,GRHL3,ATXN1,DKC1,SMAD3,IKZF4,SIX5,ADNP,KLF4,COPS5,CEBPZ,ARNTL,PUS1,SCARB1,HEATR1,PKIB,DNAJC2,MAP3K13,SUPT6H,CAMK1,AGO2,ATF7IP,BMP6,PTPN2,PRKCH,HAS3,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,ZNF821,FGF2,KDM5A,SMARCAD1,MEN1,HSPA1B,RERE,TBX3,TAF4,BCAS3,CSRNP1,NCBP2,MYRF,TAF12,RBPJ,NR2F2,NFKBIB,HRH1 |
| 1.226e-03 | -6.70 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDM_UP | 192 | 40 | 17758 | 2279 |
TCF12,MYCBP2,BIRC6,BTBD2,MRI1,MYO7A,VARS,BIRC2,PHLDA2,DCTPP1,SNW1,ASNS,ARHGAP18,MBD2,PPCDC,NDRG4,TIMELESS,CPSF3,MEIS3,MPST,SRPK2,ACADS,SSFA2,ANAPC13,SLC38A1,MTIF2,AKAP12,KRTCAP2,CORIN,C8orf33,DDX60,KLF6,EVI5,RERE,RBBP8,VPS37B,MPV17,CTAGE5,BLMH,PKIB |
| 1.226e-03 | -6.70 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN | 192 | 40 | 17758 | 2279 |
ARHGAP26,MYCBP2,SART1,ATRX,PRKCSH,FAM189B,ST6GAL1,SMG7,NECAP1,RSRC1,UBE3A,SOCS1,NOP16,BANF1,SHMT2,SCAF11,BRD4,OSBP2,GON4L,GPHN,SIGMAR1,EYA3,WBSCR22,R3HDM1,PEAK1,RBM28,UBE2K,TMEM206,NR2F1,DCBLD2,KPNA1,FAM135A,ZCCHC6,PTRH2,SLC4A7,SENP3,APAF1,PFDN2,ZMAT3,LPP |
| 1.226e-03 | -6.70 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN | 192 | 40 | 17758 | 2279 |
SEPHS2,SRM,CARS,C10orf2,TUBB6,TIMM10,CIAPIN1,DCTPP1,FARSA,ZBED2,SOCS1,DNAJB6,PPCDC,EXOSC4,MAP3K14,MGLL,GNG5,SERBP1,PTPRK,PEA15,GARS,IFNGR2,NPM3,WDR18,BMS1,TARS,MFN2,BATF3,YIF1A,POP1,PWP1,VDR,HPRT1,MTHFD2,TRAP1,SQLE,UMPS,PDCD11,TESC,IPO4 |
| 1.226e-03 | -6.70 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN | 192 | 40 | 17758 | 2279 |
MCM10,PRPF31,PLRG1,REEP5,PABPC4,FDX1,FARSA,GART,PHF5A,NOP16,BANF1,TNPO3,ETF1,SSBP1,LONP1,IPO11,ELOF1,TMPO,FAM98A,TIMM8B,GARS,WDR61,PSAT1,ITPA,CDK4,PSMA1,PSMG1,MARCKSL1,ABCF1,STOML2,PGD,MTHFD2,CDC16,G6PD,CUL2,H2AFX,GPN1,ACP1,ZRANB2,ANAPC4 |
| 1.226e-03 | -6.70 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | 192 | 40 | 17758 | 2279 |
PAFAH1B1,TMEM183A,SLC2A1,DBF4,ID2,JMJD6,C1orf52,FOSL2,HDDC2,EIF2S2,SLC39A7,YARS,LONP1,SAP30,ATF4,SLC3A2,SLC38A1,CLYBL,NARS,PCCA,RSBN1,PRDM1,DCUN1D5,GPNMB,CYB5B,FLVCR1,PLIN2,BAZ1A,YIF1A,LSS,INSIG1,SYNCRIP,HIF1A,CCNT1,FDPS,HK2,CTAGE5,PTP4A2,ECHDC1,XPO6 |
| 1.229e-03 | -6.70 | AT_hook_DNA-bd_motif | interpro domains | IPR017956 | 27 | 10 | 18293 | 2341 |
HMGA2,SRCAP,ASH1L,BAZ2A,GLYR1,PDS5B,KMT2C,KMT2A,ZBTB24,DOT1L |
| 1.231e-03 | -6.70 | regulation of mitotic metaphase/anaphase transition | biological process | GO:0030071 | 45 | 14 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,NEK6,NSMCE2,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 1.236e-03 | -6.70 | GACTGTT,MIR-212,MIR-132 | MSigDB lists | GACTGTT,MIR-212,MIR-132 | 156 | 34 | 17758 | 2279 |
HMGA2,SSH2,MYCBP2,FEM1C,LIN28B,ARID2,FOXO3,SEMA6A,POM121,PAIP2,NDRG4,PRICKLE2,RDX,SOX6,HNRNPM,HN1,PEA15,PCGF3,PXN,PTBP2,EIF4A2,ATXN1,MEX3B,ARHGAP32,BRCA1,PNN,SOX4,DHX57,TJAP1,TCF7L1,TAF4,LARGE,PURB,MMP16 |
| 1.236e-03 | -6.70 | regulation of mRNA polyadenylation | biological process | GO:1900363 | 11 | 6 | 16441 | 2138 |
RNF40,CTR9,NCBP2,SUPT5H,CCNT1,CDK9 |
| 1.236e-03 | -6.70 | regulation of nucleobase-containing compound transport | biological process | GO:0032239 | 11 | 6 | 16441 | 2138 |
RIPK1,NCBP2,SUPT6H,ZC3H3,KHDRBS1,SETD2 |
| 1.236e-03 | -6.70 | IMP biosynthetic process | biological process | GO:0006188 | 11 | 6 | 16441 | 2138 |
ADSL,HPRT1,AMPD3,GART,PPAT,ATIC |
| 1.237e-03 | -6.69 | XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6) | protein interactions | 2547 | 254 | 54 | 16036 | 2270 |
HMGA2,CUL7,MAP2K5,JUP,FN1,ATRX,SIRT7,SMAD7,CSNK2A1,TERF2IP,TADA3,ABL1,GART,UBE3A,ACD,PPID,APLF,FMNL1,MYC,SHMT2,SRRM2,TERF2,SNU13,PDK1,APEX1,NARS,SIRT6,PPARG,SMARCAD1,HSPA5,ZNF512B,POU2F1,LIG4,BRCA1,SUPT5H,TCF7L2,HERPUD1,ISG15,CHAF1A,RPA1,ANXA1,SMAD3,BAZ1A,SKIL,MSX2,TP53BP1,COPS5,SET,CUL2,H2AFX,DLX2,CLU,XRCC4,NIT1 |
| 1.237e-03 | -6.69 | KEGG_DNA_REPLICATION | MSigDB lists | KEGG_DNA_REPLICATION | 36 | 12 | 17758 | 2279 |
RFC4,RFC3,MCM6,POLE2,PRIM2,POLA1,MCM5,SSBP1,POLE3,MCM2,RNASEH2B,RPA1 |
| 1.242e-03 | -6.69 | positive regulation of multi-organism process | biological process | GO:0043902 | 160 | 35 | 16441 | 2138 |
CHMP2A,ANKRD17,CACNA1H,SMARCA4,TRIM15,RSF1,SIRT2,PRKCA,BMP6,PDE3A,SMARCB1,ELL,SNW1,PPID,GTF2H1,VAPB,LRSAM1,SRPK2,ADARB1,GTF2H3,RAB7A,LGALS1,TCEB3,NELFA,SUPT5H,PLCB1,DDX60,POLR2A,DDX3X,SUPT4H1,CCNT1,CDK9,VPS37B,NCBP2,CHMP4C |
| 1.242e-03 | -6.69 | GSE3982_BASOPHIL_VS_TH2_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH2_UP | 180 | 38 | 17758 | 2279 |
ZNF516,CELSR1,CLK1,PAFAH1B1,PSTPIP2,NECAP1,ST3GAL6,GDPD5,GIT2,POGZ,FLNB,CTNNBL1,ZNF586,PTGS1,CEP63,RREB1,KDM5A,ARHGEF10,R3HDM2,TRIM37,PLCB1,BSN,ANXA1,PEX1,BAZ2B,RPL28,UBAP1,LSM14A,TTC38,ZZEF1,AGTPBP1,RRAGA,RAD51B,SVIL,IFITM2,TPM1,MAP2K4,N4BP2L2 |
| 1.246e-03 | -6.69 | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP | 168 | 36 | 17758 | 2279 |
VIPR1,SMAD7,SMG7,ATG2B,IP6K2,PITPNM1,ABL1,FMNL1,ACAP3,UBAP2L,GLTP,MGLL,AUP1,SNX29,CARM1,SIK3,PPP1R9B,ATF4,DDX24,ATG9A,TLE3,MED27,HOMER2,PREX1,MARCH6,SUPT5H,USP36,POLR2A,INF2,TOE1,ATAD5,PDLIM1,CCNT1,PER1,ARNTL,XPNPEP1 |
| 1.247e-03 | -6.69 | regulation of mitotic cell cycle | biological process | GO:0007346 | 475 | 85 | 16441 | 2138 |
CHMP2A,CUL7,CUL4A,CYLD,PAFAH1B1,PLRG1,CSNK2A1,SMARCA4,PBX1,SIRT2,PRKCA,NLE1,GBF1,MAP2K3,SBDS,TOM1L1,ANAPC1,ASNS,NEK6,ANAPC11,ANAPC10,MAD1L1,LSM10,CTC1,BRD4,CDK4,ASUN,SOX4,TTC28,STK10,DDX3X,SMAD3,CAMK2D,CDC16,BRCA2,TRRAP,TOM1L2,NSMCE2,RAD51B,RPS6KB1,CHMP4C,HMGA2,TNIK,MINK1,XPC,ANKRD17,SLK,TCF3,PID1,ID2,PPP1R1C,RNASEH2B,GIGYF2,CDC73,PSMF1,MAD2L2,RNF40,TRIAP1,RDX,FBXO31,MAP3K14,PRMT5,DMRT1,CAV2,PPP1R9B,CRADD,FOXN3,FZD3,TEX14,PSMA1,SMARCD3,TPRA1,PLCB1,FOXC1,ZNF655,UBE2E1,UBC,ANXA1,OXSR1,KLHL22,CDK9,ATM,BMP4,ANAPC4,STK4 |
| 1.251e-03 | -6.68 | USP11 (ubiquitin specific peptidase 11) | protein interactions | 8237 | 100 | 26 | 16036 | 2270 |
FBXO45,USP7,MYCBP2,GARS,XPC,POLR1A,SIRT7,OSBPL9,SMAD7,XPO7,GIGYF2,RING1,UBC,DYRK1B,FARSA,BRCA2,RELB,RNF2,POLR1B,PGAM5,POLR1C,USP11,BMI1,AMOT,PRMT3,USP15 |
| 1.258e-03 | -6.68 | circadian regulation of gene expression | biological process | GO:0032922 | 60 | 17 | 16441 | 2138 |
ATF4,NPAS2,KDM5A,ID2,BHLHE40,NAMPT,MYBBP1A,ZFHX3,PER1,ARNTL,RELB,NCOR1,PRMT5,NRIP1,NOCT,KMT2A,TOP1 |
| 1.261e-03 | -6.68 | ribonucleotide metabolic process | biological process | GO:0009259 | 320 | 61 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,NDUFB5,PDE4B,OLA1,APRT,CHCHD10,RNASEH2B,COX10,HSPA1A,NDUFS7,PDE3A,NDUFB3,CAD,AMPD3,GART,NDUFV1,ENTPD5,ATP5G2,PDE10A,ATIC,PPCDC,MYH3,CMPK1,NDUFA6,FXN,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,PDE4A,PPAT,ITPA,UPP1,SULT4A1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,PDE8B,SNCA,STOML2,ATP5D,HPRT1,NME7,COQ9,HK2,SURF1,UMPS,NDUFS5,BPNT1,ADK,PDE9A |
| 1.264e-03 | -6.67 | protein modification process | biological process | GO:0036211 | 2835 | 419 | 16441 | 2138 |
PTP4A1,MYCBP2,CUL4A,DPH1,PRKCSH,PRKAB2,HLTF,PRKCA,NUP160,UBR5,NEK6,RNF111,DPH6,FNIP2,KDM5C,FXN,FUT11,CDK6,PPM1K,SEH1L,NRAS,SETD1B,KLHL23,PTPRM,EHMT1,EYA3,TCEB3,DCUN1D5,ZDHHC14,SPOP,DOT1L,BRCA2,TRRAP,SSU72,RAD18,CCNT1,SH3RF1,NSMCE1,RIOK1,CCNB1IP1,BMI1,BLMH,SPOCK2,SPOCK3,PTPN14,MEF2C,HERC2,WDR75,EP400,SLK,ST6GAL1,TRIO,SIRT7,PIK3R4,DPM3,TGFBR2,CDC73,CHD5,ABCA7,PRKCE,FKBP1A,UBE3A,ENTPD5,USPL1,COPS3,MYC,PIGG,MED24,PRMT5,CNOT4,MAP3K12,PEA15,SIK3,GTF2H3,SYNGAP1,ALG6,ANAPC13,WDR61,STAG1,RB1CC1,PTPN12,USP10,ATAT1,ST6GALNAC3,TRIM37,USP46,ARIH2,IRS1,SEC31A,EHMT2,NSF,CDK9,RIOK3,SENP3,MACROD1,SMYD3,C18orf25,MAP2K4,MAP2K5,BIRC6,PDK4,DDR2,KLHL18,NUP43,PTPRG,ST3GAL6,UBL5,RING1,PHC2,PRKD3,SHC1,KDM2A,PPID,UCHL5,WAC,SOCS6,TTC3,PXK,KMT2A,CDK12,KMT2D,BRD4,PDK1,STAMBP,PCMT1,DLG4,MARCH6,KCNH3,SETD7,DSP,STK10,ERC1,SERP1,FKBP3,FGFR1,FBXL5,CAMK2D,CDC16,NSMCE2,HIPK2,CAMKMT,LARGE,ACP1,RPS6KB1,TRAF3,BRCC3,SETD6,XRCC4,YEATS2,TRIM36,HMGA2,SSH2,BRAF,XPC,B4GALT5,TCF3,TRAK1,JMJD6,GAS6,LIAS,TRIM22,IKBKAP,TGFB2,RPS6KA5,RSRC1,PSMF1,NEDD4,POM121,TTLL11,TADA3,ABL1,NPRL2,SUV39H2,LTN1,COPS7B,MAP3K14,FBXL19,LYPLA2,SPTAN1,CLK2,FGF9,PXN,TTLL5,USP42,TBRG4,PTK2,UBE2K,UBC,ANXA1,RPA1,OXSR1,TRIB3,KLHL22,SRCAP,FBXO21,NSD1,ZDHHC11,HERC1,SRD5A3,RNF138,ATM,PTPN4,BMP4,PGAM5,MTMR1,ANAPC4,KDM4C,LRRC41,KAT6A,STK4,PIGM,CUL7,FEM1C,TRIM16,NF1,KMT2E,PTPRA,HECTD3,TRPM6,RCHY1,CSNK2A1,PLOD1,PPIL1,RNF43,BCOR,SIRT2,STK33,SEC16A,BIRC2,MAP2K3,ABL2,ANAPC1,COPS4,CNIH3,KANSL1,PHKA1,ATG3,ANAPC11,ANAPC10,TRIML2,IPP,POLE3,SLC35C2,GALNT18,PRKACB,CARM1,TIMM50,PTPRK,SRPK2,TNK2,TRIM13,RBCK1,GCNT2,SIRT6,BAZ2A,CDK4,MED27,COL4A3BP,GMFB,ATG12,SUMO3,KSR2,HDAC8,BRCA1,CAV1,SGK2,KCNH2,KMT2C,ST3GAL5,PAF1,DYRK1B,MSRA,UBE3D,HLCS,PER1,SOCS4,CTAGE5,PPP3CC,ASB3,GALNT10,COPS6,DCAF5,USP15,FBXO45,CTU2,TTN,PIGN,FN1,FOXO1,CLK1,SEC24D,TAF1,MAPK8IP3,SMAD7,LAMTOR3,ALG8,EVPL,RHBDD1,RNF141,RNF40,P3H1,ISPD,PPIL2,GTF2H1,CTR9,SYNJ2,LRSAM1,TRAPPC9,CAMKK2,USP49,ELP3,SETD2,OBSCN,PSMA1,MEX3B,EIF2A,TRAPPC6B,TMEM241,ISG15,UBE2E1,MGAT2,ATXN7,SPAG9,IRAK2,CASS4,HMBS,TBL1X,PTP4A2,TBCK,BRSK2,NAPA,RNF114,USP7,MPI,ASH1L,CYLD,PIGH,PPP2R2A,RIPK1,RNF24,ARSJ,CSTA,PIBF1,KDM1A,RIOK2,CAD,KCTD11,SOCS1,LYPLAL1,GRIN2C,UBR1,NUP133,RPS6KL1,IKBKB,ZDHHC6,ETF1,RNF2,ADCK4,MET,PRMT3,PRPF19,SEC24A,KAT8,PARP2,AKAP13,ENC1,EDEM2,NUP214,UBR4,USP36,RANBP2,COPS5,ATG7,DUSP19,FKBP5,MED20,RNF130,USP11,PPIL3,SMG1,KLHL24,BCKDK,TNIK,ESCO1,MINK1,SH2D3A,MAP3K13,CAMK1,CSNK1A1,MAN1A1,PTPN2,PRKCH,ADH5,CWC27,SEC24C,FBXO31,FBL,RPS6KB2,MARCH9,KDM6B,GPHN,KDM5B,FGF2,SMARCAD1,TEX14,SCMH1,HIST1H4J,MEN1,PEAK1,NEU1,ALG5,AGTPBP1,CUL2,EIF2S1,FNTB,USP20,TAF12,RPS6KC1,ZAK |
| 1.264e-03 | -6.67 | cellular protein modification process | biological process | GO:0006464 | 2835 | 419 | 16441 | 2138 |
PTP4A1,MYCBP2,CUL4A,DPH1,PRKCSH,PRKAB2,HLTF,PRKCA,NUP160,UBR5,NEK6,RNF111,DPH6,FNIP2,KDM5C,FXN,FUT11,CDK6,PPM1K,SEH1L,NRAS,SETD1B,KLHL23,PTPRM,EHMT1,EYA3,TCEB3,DCUN1D5,ZDHHC14,SPOP,DOT1L,BRCA2,TRRAP,SSU72,RAD18,CCNT1,SH3RF1,NSMCE1,RIOK1,CCNB1IP1,BMI1,BLMH,SPOCK2,SPOCK3,PTPN14,MEF2C,HERC2,WDR75,EP400,SLK,ST6GAL1,TRIO,SIRT7,PIK3R4,DPM3,TGFBR2,CDC73,CHD5,ABCA7,PRKCE,FKBP1A,UBE3A,ENTPD5,USPL1,COPS3,MYC,PIGG,MED24,PRMT5,CNOT4,MAP3K12,PEA15,SIK3,GTF2H3,SYNGAP1,ALG6,ANAPC13,WDR61,STAG1,RB1CC1,PTPN12,USP10,ATAT1,ST6GALNAC3,TRIM37,USP46,ARIH2,IRS1,SEC31A,EHMT2,NSF,CDK9,RIOK3,SENP3,MACROD1,SMYD3,C18orf25,MAP2K4,MAP2K5,BIRC6,PDK4,DDR2,KLHL18,NUP43,PTPRG,ST3GAL6,UBL5,RING1,PHC2,PRKD3,SHC1,KDM2A,PPID,UCHL5,WAC,SOCS6,TTC3,PXK,KMT2A,CDK12,KMT2D,BRD4,PDK1,STAMBP,PCMT1,DLG4,MARCH6,KCNH3,SETD7,DSP,STK10,ERC1,SERP1,FKBP3,FGFR1,FBXL5,CAMK2D,CDC16,NSMCE2,HIPK2,CAMKMT,LARGE,ACP1,RPS6KB1,TRAF3,BRCC3,SETD6,XRCC4,YEATS2,TRIM36,HMGA2,SSH2,BRAF,XPC,B4GALT5,TCF3,TRAK1,JMJD6,GAS6,LIAS,TRIM22,IKBKAP,TGFB2,RPS6KA5,RSRC1,PSMF1,NEDD4,POM121,TTLL11,TADA3,ABL1,NPRL2,SUV39H2,LTN1,COPS7B,MAP3K14,FBXL19,LYPLA2,SPTAN1,CLK2,FGF9,PXN,TTLL5,USP42,TBRG4,PTK2,UBE2K,UBC,ANXA1,RPA1,OXSR1,TRIB3,KLHL22,SRCAP,FBXO21,NSD1,ZDHHC11,HERC1,SRD5A3,RNF138,ATM,PTPN4,BMP4,PGAM5,MTMR1,ANAPC4,KDM4C,LRRC41,KAT6A,STK4,PIGM,CUL7,FEM1C,TRIM16,NF1,KMT2E,PTPRA,HECTD3,TRPM6,RCHY1,CSNK2A1,PLOD1,PPIL1,RNF43,BCOR,SIRT2,STK33,SEC16A,BIRC2,MAP2K3,ABL2,ANAPC1,COPS4,CNIH3,KANSL1,PHKA1,ATG3,ANAPC11,ANAPC10,TRIML2,IPP,POLE3,SLC35C2,GALNT18,PRKACB,CARM1,TIMM50,PTPRK,SRPK2,TNK2,TRIM13,RBCK1,GCNT2,SIRT6,BAZ2A,CDK4,MED27,COL4A3BP,GMFB,ATG12,SUMO3,KSR2,HDAC8,BRCA1,CAV1,SGK2,KCNH2,KMT2C,ST3GAL5,PAF1,DYRK1B,MSRA,UBE3D,HLCS,PER1,SOCS4,CTAGE5,PPP3CC,ASB3,GALNT10,COPS6,DCAF5,USP15,FBXO45,CTU2,TTN,PIGN,FN1,FOXO1,CLK1,SEC24D,TAF1,MAPK8IP3,SMAD7,LAMTOR3,ALG8,EVPL,RHBDD1,RNF141,RNF40,P3H1,ISPD,PPIL2,GTF2H1,CTR9,SYNJ2,LRSAM1,TRAPPC9,CAMKK2,USP49,ELP3,SETD2,OBSCN,PSMA1,MEX3B,EIF2A,TRAPPC6B,TMEM241,ISG15,UBE2E1,MGAT2,ATXN7,SPAG9,IRAK2,CASS4,HMBS,TBL1X,PTP4A2,TBCK,BRSK2,NAPA,RNF114,USP7,MPI,ASH1L,CYLD,PIGH,PPP2R2A,RIPK1,RNF24,ARSJ,CSTA,PIBF1,KDM1A,RIOK2,CAD,KCTD11,SOCS1,LYPLAL1,GRIN2C,UBR1,NUP133,RPS6KL1,IKBKB,ZDHHC6,ETF1,RNF2,ADCK4,MET,PRMT3,PRPF19,SEC24A,KAT8,PARP2,AKAP13,ENC1,EDEM2,NUP214,UBR4,USP36,RANBP2,COPS5,ATG7,DUSP19,FKBP5,MED20,RNF130,USP11,PPIL3,SMG1,KLHL24,BCKDK,TNIK,ESCO1,MINK1,SH2D3A,MAP3K13,CAMK1,CSNK1A1,MAN1A1,PTPN2,PRKCH,ADH5,CWC27,SEC24C,FBXO31,FBL,RPS6KB2,MARCH9,KDM6B,GPHN,KDM5B,FGF2,SMARCAD1,TEX14,SCMH1,HIST1H4J,MEN1,PEAK1,NEU1,ALG5,AGTPBP1,CUL2,EIF2S1,FNTB,USP20,TAF12,RPS6KC1,ZAK |
| 1.265e-03 | -6.67 | TCCATTKW_UNKNOWN | MSigDB lists | TCCATTKW_UNKNOWN | 223 | 45 | 17758 | 2279 |
MAP2K5,MAP3K13,SUPT6H,SLC48A1,NFX1,ENAH,RNF43,SPATS2,IP6K2,TMEM132A,BZW2,SEMA6A,PABPC4,PLXNB1,DST,GART,NAV1,ATP5G2,FSIP2,RNF111,CHD2,IGF2BP1,ZNF710,ZMYM2,SOBP,ENHO,RAB7A,TLE3,ANKMY2,ZMYM5,SETD2,VSNL1,PRDM1,SOX4,ZSCAN2,SON,FGFR1,BSN,CXADR,GTF2A1,SYNCRIP,PER1,CCDC85B,CLU,ZAK |
| 1.273e-03 | -6.67 | positive regulation of mitotic cell cycle phase transition | biological process | GO:1901992 | 55 | 16 | 16441 | 2138 |
CUL4A,BRD4,ANKRD17,CDK4,PLRG1,PBX1,SMARCD3,PPP1R1C,PLCB1,ANXA1,DDX3X,NSMCE2,ANAPC11,RAD51B,RDX,LSM10 |
| 1.273e-03 | -6.67 | nucleoside monophosphate biosynthetic process | biological process | GO:0009124 | 81 | 21 | 16441 | 2138 |
AK2,PPAT,UPP1,ATP6V0A1,ADSL,APRT,CHCHD10,IMPDH2,ATP5D,STOML2,CAD,AMPD3,HPRT1,GART,ATP5G2,ATIC,SURF1,UMPS,CMPK1,ADK,PRPS1 |
| 1.277e-03 | -6.66 | ACAACTT,MIR-382 | MSigDB lists | ACAACTT,MIR-382 | 66 | 18 | 17758 | 2279 |
ZCCHC14,BDNF,SMARCAD1,ZNF280C,GMFB,NFIA,MBNL2,SYT1,MBNL1,ARID1B,ARIH2,MTUS1,DDX3X,NSRP1,SEC24C,PPP3CC,MMP16,TOP1 |
| 1.277e-03 | -6.66 | DNA_DIRECTED_RNA_POLYMERASEII_HOLOENZYME | MSigDB lists | DNA_DIRECTED_RNA_POLYMERASEII_HOLOENZYME | 66 | 18 | 17758 | 2279 |
SCAF11,TAF1,PPARGC1B,ELP3,MED18,MED16,IKBKAP,POLR2A,TAF2,INTS7,INTS5,TAF4,INTS9,GTF2H1,INTS12,ZNF148,TAF12,CPSF3L |
| 1.277e-03 | -6.66 | V$ARNT_01 | MSigDB lists | V$ARNT_01 | 248 | 49 | 17758 | 2279 |
CELSR3,SPATA2L,ATP6V1A,DYM,UBXN1,RTN4,ATF7IP,TGFB2,RLF,UBR5,MBNL1,SLC39A11,MTUS1,RSPRY1,FAM192A,JAG1,SLC38A5,ATG3,VGF,DCTN4,GTF2H1,IGF2BP1,ETV1,ZCCHC7,PRPS1,SERBP1,NUDC,BDNF,TXLNG,SIGMAR1,PPAT,ARRDC3,KIAA0586,AKAP12,SNAP25,ODC1,NOP58,UBR4,BATF3,RPA1,DDX3X,SYNCRIP,PER1,VPS37B,SRFBP1,EME1,BMP4,KAT6A,NIT1 |
| 1.278e-03 | -6.66 | RANGAP1 (Ran GTPase activating protein 1) | protein interactions | 5905 | 95 | 25 | 16036 | 2270 |
PMS1,CUL7,PRDX6,ACTR3,SIRT7,COL4A3BP,SUMO3,CSNK2A1,GNL1,RANGAP1,SUPT5H,UBR5,UBR4,GNAI1,RANBP2,SUB1,TPD52L2,KDM2A,USPL1,RNF2,GTF3C3,RAN,BAG1,IPO11,LPP |
| 1.278e-03 | -6.66 | MRE11A (MRE11 homolog A, double strand break repair nuclease) | protein interactions | 4361 | 95 | 25 | 16036 | 2270 |
RFC4,CUL7,ATRX,POLA1,SIRT7,FANCD2,BRCA1,MLH1,MCM2,ABCF1,UBC,RPA1,IGF2BP3,TERF2IP,TRRAP,RBBP8,SMARCC1,H2AFX,ATM,EIF2B3,YBX3,USP11,HNRNPM,TERF2,TMPO |
| 1.278e-03 | -6.66 | snoRNA localization | biological process | GO:0048254 | 5 | 4 | 16441 | 2138 |
FBL,PRPF31,NOP58,ZNHIT6 |
| 1.278e-03 | -6.66 | positive regulation of histone ubiquitination | biological process | GO:0033184 | 5 | 4 | 16441 | 2138 |
RNF40,CTR9,CDK9,KDM1A |
| 1.278e-03 | -6.66 | nucleolus organization | biological process | GO:0007000 | 5 | 4 | 16441 | 2138 |
PES1,RRN3,POLR1B,NOLC1 |
| 1.278e-03 | -6.66 | snRNA transcription from RNA polymerase III promoter | biological process | GO:0042796 | 5 | 4 | 16441 | 2138 |
ELL,ICE2,ZC3H8,SNAPC4 |
| 1.283e-03 | -6.66 | AACTGAC,MIR-223 | MSigDB lists | AACTGAC,MIR-223 | 93 | 23 | 17758 | 2279 |
ZCCHC14,PTBP2,ANKRD17,CRIM1,NFIA,WDR26,PRDM1,SON,FOXO3,SCAF8,SLC39A1,SLC23A2,UBTF,SACS,KPNA3,KIAA0355,PDS5B,PURB,RPS6KB1,RBPJ,MMP16,PKNOX1,MEF2C |
| 1.284e-03 | -6.66 | Pribosyltran | pfam domains | PF00156 | 5 | 4 | 16629 | 2165 |
APRT,HPRT1,UMPS,PPAT |
| 1.284e-03 | -6.66 | PABP | pfam domains | PF00658 | 5 | 4 | 16629 | 2165 |
PABPC1L,PABPC1,UBR5,PABPC4 |
| 1.294e-03 | -6.65 | MARTENS_BOUND_BY_PML_RARA_FUSION | MSigDB lists | MARTENS_BOUND_BY_PML_RARA_FUSION | 422 | 76 | 17758 | 2279 |
ID1,RWDD1,ARID2,MYH9,TMEM104,FOSL2,LTB4R,DENND3,FLNB,MAP2K3,SKI,CHD7,BRE,NEK6,ZFYVE28,FMNL1,PPCDC,ANKRD11,MGLL,UPP1,ANKRD33B,CUX1,RFX2,PREX1,C5AR1,GALK2,MEF2D,COTL1,NUDT15,DOT1L,YTHDF2,ZC3H12A,SMAD3,RBBP8,SCARB1,KLHDC4,RUNX1,NOLC1,KLHL24,BANP,NCOR2,AUH,PGPEP1,LETMD1,SF3A3,ID2,WDR26,BHLHE40,DDIT4,KRI1,ELL,MCAM,MCM5,BANF1,DCTN4,EXOSC4,ZNF710,PLEKHA2,HNRNPM,LRRC20,PXN,TRNP1,RAP1GAP2,TBXAS1,TPRA1,PGD,TPD52L2,NME1-NME2,ARID3B,CDK9,ZZEF1,SLC25A19,MBD6,PSAP,SH3PXD2A,TESC |
| 1.301e-03 | -6.64 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | 318 | 60 | 17758 | 2279 |
HERC2,ARHGAP26,PIGN,PCNT,FOXO1,NF1,CCDC53,ANKRD17,PAFAH1B1,PAX2,C16orf45,FAN1,MED13L,SPATS2L,TOM1L1,CHD7,DST,RGS17,SYN2,STC2,RNF111,KIAA0922,MET,TMEM120B,SAMD4A,MYB,PCSK6,ZCCHC14,DNMBP,PTBP2,SLC38A1,TSPYL4,ANK2,RAP1GAP2,RAPGEF4,TEX14,PCMT1,SATB2,POLG2,ZNF91,TRIM37,WARS,FBXL5,IFT81,HPRT1,ASCC3,SYNCRIP,GADD45A,ASTN2,ZNF330,COQ9,AGTPBP1,RRAGA,BBIP1,RBPJ,ADK,ANKS1A,KIF1B,KDM4C,TRIM36 |
| 1.316e-03 | -6.63 | BCAT1 (branched chain amino-acid transaminase 1, cytosolic) | protein interactions | 586 | 29 | 11 | 16036 | 2270 |
HELZ,DUS3L,ARID3B,PER1,ATXN2,PUS1,PSAP,AGL,YEATS2,KDM1A,USP15 |
| 1.316e-03 | -6.63 | ANAPC10 (anaphase promoting complex subunit 10) | protein interactions | 10393 | 29 | 11 | 16036 | 2270 |
SMAD3,ANAPC1,CDC16,TP53BP1,PLPPR2,TAF3,ANAPC11,UTP15,CBWD1,LIG4,ANAPC4 |
| 1.316e-03 | -6.63 | EFTUD1 (elongation factor Tu GTP binding domain containing 1) | protein interactions | 79631 | 21 | 9 | 16036 | 2270 |
TPD52L2,TRIP6,SKIV2L2,ABCF2,RANGAP1,MID1,BAG1,SBDS,LPP |
| 1.324e-03 | -6.63 | SF3B3 (splicing factor 3b subunit 3) | protein interactions | 23450 | 170 | 39 | 16036 | 2270 |
USP7,SART1,CUL7,CUL4A,UTP14A,PRPF31,PLRG1,SF3A3,PPIL1,SRSF2,UBE3A,BCAS2,PHF5A,RNF2,SRRM2,HNRNPM,TOP1,PRPF19,SPTAN1,MTHFD1,SF3A1,SMARCAD1,TRA2A,ZC3H18,WDR18,USP10,RPA1,TJAP1,STOML2,TOE1,SYNCRIP,HNRNPR,COPS5,TAF4,CUL2,PRPF4,FUS,NCOR1,TNFRSF10D |
| 1.324e-03 | -6.63 | JUN kinase binding | molecular function | GO:0008432 | 5 | 4 | 16491 | 2164 |
PTK2,SPAG9,MAD2L2,MAPK8IP3 |
| 1.328e-03 | -6.62 | PCNA (proliferating cell nuclear antigen) | protein interactions | 5111 | 249 | 53 | 16036 | 2270 |
POLB,CUL7,CUL4A,FN1,PRDX6,FANCD2,FAN1,HLTF,MLH1,FOXO3,DCTPP1,ABL1,SUB1,SLX4,PDS5B,TIMELESS,KDM5C,CDK6,TOP1,RPS6KB2,SNU13,RFC4,RFC3,APEX1,KRT7,POLK,POLA1,CDK4,SMARCAD1,ELP3,LDHA,USP10,MCL1,BRCA1,POLR2A,CHAF1A,RPA1,ZRANB3,WARS,EXO1,ATAD5,BRCA2,RBBP8,MYBBP1A,RAD18,GADD45A,CUL2,MSH3,XPNPEP1,PUS1,FUS,ANXA2,MUTYH |
| 1.329e-03 | -6.62 | chr3p25 | MSigDB lists | chr3p25 | 61 | 17 | 17758 | 2279 |
OXNAD1,XPC,PPARG,CAMK1,FANCD2,IL17RE,TAMM41,TADA3,RAD18,SYN2,SETD5,METTL6,IRAK2,ATG7,PRRT3,TSEN2,HRH1 |
| 1.335e-03 | -6.62 | V$TAL1ALPHAE47_01 | MSigDB lists | V$TAL1ALPHAE47_01 | 236 | 47 | 17758 | 2279 |
TCF12,SSH2,TTN,DLL4,RHOBTB1,NPAS2,PDE4B,KLHL18,HES6,FOXP1,RADIL,SCN1B,NCKIPSD,STC2,KIAA0922,ZNF710,PNMA1,NAV3,SOBP,FGF9,FMNL3,BRD4,STAG1,ZNF821,LIMA1,KIRREL2,NR6A1,EYA3,ARRDC3,ATG12,WWC1,TRIM37,MBNL2,ONECUT2,PLCB1,EXOC6,TJAP1,HTR7,SMAD3,DDAH2,ARL4A,RIOK3,MBD6,DDIT3,KDM4C,RAB30,MEF2C |
| 1.336e-03 | -6.62 | RRP7A (ribosomal RNA processing 7 homolog A) | protein interactions | 27341 | 42 | 14 | 16036 | 2270 |
NAP1L5,GNG2,RANBP2,SNU13,MYBBP1A,TFIP11,GNL3,SIRT7,NFIA,NOL6,RNF2,UPF2,NOLC1,HNRNPM |
| 1.337e-03 | -6.62 | ATM (ATM serine/threonine kinase) | protein interactions | 472 | 132 | 32 | 16036 | 2270 |
XPC,SIRT7,SMAD7,FANCD2,MLH1,AP1B1,TTI1,FOXO3,SMARCB1,ABL1,RNF40,SOCS1,ZEB1,ATRIP,TERF2,TOP1,KAT8,LIG4,BRCA1,MCM2,POLR2A,SPOP,RPA1,EXO1,RBBP8,BRCA2,HIF1A,TP53BP1,CDK9,H2AFX,ATM,BMI1 |
| 1.341e-03 | -6.61 | oxoacid metabolic process | biological process | GO:0043436 | 984 | 160 | 16441 | 2138 |
GGT1,RARS2,PRKAB2,AARS2,SLC25A21,PLOD1,SLC6A8,AARS,AHCYL2,LPIN1,PCYOX1L,FAAH2,PPCDC,HYAL1,SUCLG2,ME1,SLC27A5,YARS,PPM1K,MPST,CSGALNACT2,ACADS,SESN2,ATF4,PPARG,HARS,ALDH1L2,BRCA1,MTHFD1L,DLST,ODC1,ST3GAL5,MPC1,PYCR1,GLS,MSRA,DDAH2,HLCS,BDH2,TNFRSF1A,ABCC3,SPOCK2,SPOCK3,RBP1,SEPHS2,XYLB,CARS,SARS,CHST11,LARS2,ST6GAL1,HSD17B10,PLA2G12A,PHGDH,ETFB,YARS2,ATIC,ALDH18A1,PPA1,MTHFD1,FADS1,WARS2,PPAT,ELOVL6,PCCA,RDH10,IDH3G,TBXAS1,CPT1A,ACOXL,MTR,PGD,DAGLA,EPRS,MTHFD2,GSTO2,HIF1A,VCAN,D2HGDH,HK2,SLC16A1,DPEP1,DTD1,PEX13,BPNT1,GGT7,CNDP2,HS2ST1,CPT1C,SDSL,SUCLG1,SLC2A1,UROD,PDK4,TNXB,LPCAT3,ST3GAL6,CAD,FARSA,DECR1,ASNS,CBR4,PYCRL,LPIN2,HIBCH,AHCYL1,MTHFD2L,MGLL,TMLHE,ACSL5,MCEE,NARS2,GARS,PDK1,NARS,SLC35D1,HSD3B7,WARS,SNCA,DCXR,PEMT,ATG7,MORC2,DMGDH,SERINC5,BCKDK,AUH,SULT1C2,B4GALT5,MRI1,FARS2,VARS,LIAS,PEX7,GART,GATC,ACOT11,HARS2,SHMT2,PTGS1,PHYKPL,HSD17B12,LYPLA2,PFKFB4,PSAT1,LDHA,SULT4A1,MARS,MMAA,TARS,ECH1,SLC23A2,ETFDH,RARS,GPC2,SERINC1,DAGLB,ACOX1,GPAM,GCSH |
| 1.352e-03 | -6.61 | PPP1R15A (protein phosphatase 1, regulatory subunit 15A) | protein interactions | 23645 | 25 | 10 | 16036 | 2270 |
COPS5,IKBKB,TSN,ZNF512B,SMAD7,EIF2S1,KMT2A,HSPA1A,BAG1,SMARCB1 |
| 1.352e-03 | -6.61 | UTP20 (UTP20 small subunit (SSU) processome component) | protein interactions | 27340 | 25 | 10 | 16036 | 2270 |
VPS18,PWP1,DDX18,SIRT7,NOL6,NAT10,BMI1,NOP58,NOP56,TOP1 |
| 1.352e-03 | -6.61 | ANKMY2 (ankyrin repeat and MYND domain containing 2) | protein interactions | 57037 | 25 | 10 | 16036 | 2270 |
SURF2,ACD,SKIV2L2,KIF5C,FKBP5,DTD1,LRSAM1,AARS,AGO3,RPS6KB2 |
| 1.354e-03 | -6.60 | tRNA modification in the nucleus and cytosol | REACTOME pathways | R-HSA-6782315 | 39 | 13 | 8202 | 1117 |
METTL1,CTU2,EPRS,TRMT5,TRMT13,ADAT2,TYW1,ALKBH8,LAGE3,CDKAL1,PUS1,TRMT10A,TRMT12 |
| 1.354e-03 | -6.60 | Presynaptic phase of homologous DNA pairing and strand exchange | REACTOME pathways | R-HSA-5693616 | 39 | 13 | 8202 | 1117 |
EXO1,RFC4,RFC3,RBBP8,BRCA2,XRCC2,RAD51B,TOP3A,ATM,ATRIP,BRCA1,RMI1,RPA1 |
| 1.359e-03 | -6.60 | GSE17721_LPS_VS_POLYIC_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDM_UP | 193 | 40 | 17758 | 2279 |
SEPHS2,SRM,PTCD2,FN1,PAFAH1B1,DYM,PDE4B,SMAD7,XPO7,NUP160,RIOK2,RRN3,JAG1,NOP16,DNAJB6,PMPCA,ERI3,ITGAX,PRMT3,FDFT1,FMNL3,GNL3,EPS15L1,ST3GAL5,HSD3B7,POLR2A,SMPDL3B,PES1,PWP1,CAT,SEC31A,EPRS,TMCO1,SPEN,G6PD,ATG7,GPN1,NCBP2,NFKBIB,LPP |
| 1.359e-03 | -6.60 | GSE17721_CTRL_VS_POLYIC_1H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_1H_BMDM_UP | 193 | 40 | 17758 | 2279 |
PGPEP1,UBN1,CAMK1,APRT,WNT2B,IGF2BP3,SLC39A11,NAMPT,FAM192A,RAP1A,ACD,SOCS1,ATG3,SOCS6,RNF2,MEIS3,ATP6V0D1,CPSF3L,FAM98A,SLC40A1,SIGMAR1,ANKMY2,TFPI,LGALS1,C5AR1,ENC1,CPT1A,EVI5,SLC7A1,ALG5,IREB2,ADNP,SPEN,LUC7L3,METTL6,LARGE,TNFRSF1A,ZNF436,MSH3,SRFBP1 |
| 1.362e-03 | -6.60 | p53 binding | molecular function | GO:0002039 | 65 | 18 | 16491 | 2164 |
USP7,BANP,MSX1,BRD4,TAF1,EHMT1,RCHY1,USP10,SMARCA4,ZNF346,SETD7,KDM1A,SMARCB1,EHMT2,TAF3,TP53BP1,TRIAP1,ZMAT3 |
| 1.362e-03 | -6.60 | BROWNE_HCMV_INFECTION_24HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_DN | 145 | 32 | 17758 | 2279 |
PRKAB2,GAS6,PRKCA,TGFBR2,DST,S100A10,YLPM1,ATP5G2,SUCLG2,BCAP29,MET,CD44,FADS1,LAMA4,DNMBP,LAMC1,AP4S1,PRIM2,COL5A2,CRIM1,PTPRM,TEAD1,KCNMA1,TFPI,CAV1,TMEM187,POLR3G,ACOX1,HIPK2,ITGA2,FDPS,SEMA3C |
| 1.363e-03 | -6.60 | V$MEIS1_01 | MSigDB lists | V$MEIS1_01 | 230 | 46 | 17758 | 2279 |
KCTD7,ASH1L,NDUFAF2,PAFAH1B1,PPARGC1B,TMEM109,SLC25A12,HES6,LPCAT3,RSF1,TNKS1BP1,VPS18,ABL2,FAM192A,RSPRY1,SREBF2,IKZF5,SAMD11,METTL8,ERRFI1,ETV1,YARS,C15orf41,SOBP,DPF3,GPHN,ANK2,WWC1,PITPNB,ARRDC4,DENND4A,FKBP3,TCF7L2,SLC23A2,HTR7,BAZ1A,SPAG9,DDX50,KIAA0355,RPS6KB1,MBD6,NRP1,SPOCK2,MAPT,DDIT3,USP15 |
| 1.372e-03 | -6.59 | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | 187 | 39 | 17758 | 2279 |
NCOR2,SDSL,JUP,RHOBTB1,SESTD1,SMAD7,SPATS2L,TRIM22,DDX60L,IGF2BP3,SH2B3,ABL1,KIAA1958,IFIT5,UBAP2L,FNIP2,MGLL,FMNL2,SAMD4A,DENND1A,TBC1D8,PEA15,UPP1,USP42,PEAR1,PHACTR2,ZNFX1,PTK2,OASL,DDX60,ST3GAL5,ISG15,CHAF1A,VDR,ARHGAP21,RBBP8,XPNPEP1,IPO4,LPP |
| 1.372e-03 | -6.59 | GSE17721_0.5H_VS_8H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_8H_LPS_BMDM_UP | 187 | 39 | 17758 | 2279 |
ASCC1,SEC24D,XPC,ATRX,PIP4K2A,PAG1,FAM50A,DDX56,PHF5A,ARMC6,ATG3,MAD1L1,SOCS6,CTR9,CORO1A,TSPAN14,ZNF518B,PRMT3,KLRD1,ACADS,METTL1,MPP6,TUBA1A,CMIP,CDK4,ELOVL6,ARHGAP39,PACS1,GALK2,CPT1A,C1orf174,NEU1,ZBTB25,TPD52L2,ELP2,DCXR,DUSP19,SVIL,TMEM141 |
| 1.372e-03 | -6.59 | GSE11924_TH2_VS_TH17_CD4_TCELL_DN | MSigDB lists | GSE11924_TH2_VS_TH17_CD4_TCELL_DN | 187 | 39 | 17758 | 2279 |
TCF3,OLA1,DLGAP4,SMAD7,BHLHE40,GDPD5,MFHAS1,RING1,ABCA7,ERI1,MYC,ARHGAP1,ERI3,TMEM120B,TRIM13,MPP6,EVL,RNMT,IFT43,MON1A,ZC4H2,ELOVL6,FRA10AC1,R3HDM1,TTYH2,CAMSAP2,ODC1,PDE3B,BATF3,GNG2,RETSAT,BAZ2B,SSU72,LEMD3,EEFSEC,CUL2,ZNF236,CDKAL1,SETD6 |
| 1.372e-03 | -6.59 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | 187 | 39 | 17758 | 2279 |
RBFOX2,DDR2,RCHY1,PLA2G12A,ST7L,TGFB2,ADH5,CCDC50,LONRF2,CBR4,PTGS1,PPM1K,PRPS1,SOX6,CSGALNACT2,LAMA4,FLNC,CRIM1,WDFY3,C11orf80,NFIA,FERMT2,PTPN12,EFHC1,PLEKHM3,CAV1,GPNMB,TTC28,CRYBG3,NR2F1,DCBLD2,FBXO21,SPAG9,TMEM237,ZNF330,PREPL,ZNF532,KIF1B,SPOCK2 |
| 1.372e-03 | -6.59 | GSE13493_DP_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD8POS_THYMOCYTE_UP | 187 | 39 | 17758 | 2279 |
TCF12,SERINC5,PRPF38B,JUP,MEX3A,CD99L2,RABGAP1L,PPIL2,SHF,LYRM5,NAA35,FMNL2,LYST,RPS6KB2,ZNF646,PTBP2,TSPYL4,MANBAL,ARHGEF10,MARCKSL1,MEX3B,ARID1A,MARCH6,R3HDM2,TPRA1,SETD7,AGAP1,RDH11,CACNB1,KIDINS220,GADD45A,L3MBTL3,MKL2,CSRNP1,VPS13D,CNOT6,RBPJ,CORO2B,MORC2 |
| 1.374e-03 | -6.59 | PENG_GLUCOSE_DEPRIVATION_UP | MSigDB lists | PENG_GLUCOSE_DEPRIVATION_UP | 46 | 14 | 17758 | 2279 |
CARS,GART,ASNS,ACD,CLCN6,C11orf80,PLOD1,CORO1A,PCK2,AARS,MAP2K3,WARS,PYCR1,MYB |
| 1.374e-03 | -6.59 | SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN | 46 | 14 | 17758 | 2279 |
SYNCRIP,PPAT,TIMM17A,MYC,CEBPZ,FTSJ1,LDHA,RSL1D1,RAN,FBL,DKC1,ODC1,SRRM2,TRIM14 |
| 1.377e-03 | -6.59 | central_nervous_system-chiasm-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-chiasm-glioma-astrocytoma_Grade_I | 8 | 5 | 17775 | 2278 |
RNF130,BRAF,KIAA1549,GNAI1,CLCN6 |
| 1.382e-03 | -6.58 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP | 181 | 38 | 17758 | 2279 |
TAF1,UBN1,KIF5A,PLRG1,INPP1,TRIM66,RNFT2,JAG1,MPHOSPH10,SHC1,DUS4L,GATC,NOVA2,SYN2,TRIAP1,ACOT11,VPS52,MFAP2,ITGAX,AMOT,PABPC1,SPAG6,ZCCHC14,COL17A1,CAMKK2,TSTA3,JMJD1C,BRCA1,KCNH2,NUP214,VAC14,SLC7A1,AHNAK,RBBP8,GATA6,SVIL,PTPN4,MEF2C |
| 1.383e-03 | -6.58 | Circadian Clock | REACTOME pathways | R-HSA-400253 | 63 | 18 | 8202 | 1117 |
ARNTL2,CHD9,NPAS2,SMARCD3,MEF2D,BHLHE40,CPT1A,UBC,NAMPT,HIF1A,PER1,ARNTL,NCOR1,TBL1X,NRIP1,NOCT,CARM1,MEF2C |
| 1.389e-03 | -6.58 | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN | MSigDB lists | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN | 175 | 37 | 17758 | 2279 |
ADAM19,HM13,CCDC53,ST6GAL1,MRI1,SPATS2,PABPC1L,HMOX2,UBR5,AARS,MAN1A1,FAM192A,FLAD1,ZKSCAN1,NVL,ATXN2,SETD5,SLC39A7,METTL8,MED24,HIBCH,ALDH18A1,MAP3K12,MTHFD1,FAM120B,PMS1,ALG6,PPP1R21,MARS,CAV1,RABAC1,MEN1,ECH1,SPOP,ZBTB8OS,PDCD11,MID1 |
| 1.389e-03 | -6.58 | negative regulation of metaphase/anaphase transition of cell cycle | biological process | GO:1902100 | 36 | 12 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 1.392e-03 | -6.58 | NUCLEAR_TRANSPORT | MSigDB lists | NUCLEAR_TRANSPORT | 88 | 22 | 17758 | 2279 |
TRIP6,NF1,KHDRBS1,SMG7,ATXN1,XPO7,NUP214,NUP160,NOP58,RPAIN,RERE,SMAD3,RANBP2,KPNA1,MYBBP1A,KPNA3,NUP133,NCKIPSD,UPF2,NCBP2,XPO6,SMG1 |
| 1.396e-03 | -6.57 | HASLINGER_B_CLL_WITH_11Q23_DELETION | MSigDB lists | HASLINGER_B_CLL_WITH_11Q23_DELETION | 23 | 9 | 17758 | 2279 |
DMXL2,SIK3,SLC4A7,ATM,PCSK7,DDX10,LPCAT1,BIRC2,PABPC4 |
| 1.397e-03 | -6.57 | MEPCE (methylphosphate capping enzyme) | protein interactions | 56257 | 176 | 40 | 16036 | 2270 |
SART1,AK2,ACTG1,PRPF31,IGF2BP2,PHGDH,CDC73,NOP56,IGF2BP3,METTL16,ANP32B,IGF2BP1,FBL,YBX3,TRIP13,PRPF19,EXOSC2,SNU13,RFC4,RFC3,TRA2A,HSPA5,RANGAP1,SAP30BP,ISG15,YTHDF2,KPNA1,SYNCRIP,KPNA3,ARID3B,CCNT1,HNRNPR,CDK9,SRP68,LRRC40,LUC7L3,SET,PRPF4,BMI1,USP15 |
| 1.400e-03 | -6.57 | POLR1B (polymerase (RNA) I polypeptide B) | protein interactions | 84172 | 56 | 17 | 16036 | 2270 |
WDR36,DDX18,POLR1A,GIT2,POLR3A,RPA1,NOP56,TSR1,RRN3,EEFSEC,POLR3B,POLR1B,MED20,NFKBIB,USP11,POLR1C,POLR1E |
| 1.410e-03 | -6.56 | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | REACTOME pathways | R-HSA-5693554 | 26 | 10 | 8202 | 1117 |
EXO1,RBBP8,BRCA2,PALB2,XRCC2,RAD51B,TOP3A,ATM,BRCA1,RMI1 |
| 1.425e-03 | -6.55 | VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP | MSigDB lists | VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP | 15 | 7 | 17758 | 2279 |
RUNX1,FN1,TGFB2,INSIG1,PEG10,UBAP2L,HS2ST1 |
| 1.425e-03 | -6.55 | RRNA_PROCESSING | MSigDB lists | RRNA_PROCESSING | 15 | 7 | 17758 | 2279 |
EXOSC2,GEMIN4,FBL,DKC1,NOLC1,NOP58,NOP56 |
| 1.427e-03 | -6.55 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 797 | 131 | 17775 | 2278 |
IMMP2L,LETM1,NF1,POLR1A,TRPM6,CSNK2A1,STK33,PRKCA,NBEAL1,MAP2K3,ABL2,PDZD2,NEK6,THADA,CDK6,PRKACB,SRPK2,TNK2,NRAS,NR6A1,CDK4,TCEB3,KSR2,BRCA1,SGK2,BSN,DYRK1B,MSRA,TRRAP,VPS13D,RIOK1,BMI1,FN1,TAF1,CLK1,TRIO,CENPB,PIK3R4,TGFBR2,ARID1B,PRKCE,SEMA3D,MAP3K12,SAMD3,SIK3,CAMKK2,LAMC1,TRA2A,OBSCN,SYT1,USP46,IRS1,GRIK4,KIDINS220,SYNCRIP,SPEN,DNAH17,RIOK3,PDLIM5,TBCK,MAP2K4,DMXL2,SYT17,PCNT,ARID2,PDK4,DDR2,COBLL1,RIPK1,STAM,RIOK2,CAD,PRKD3,UBR1,RPS6KL1,PPFIBP1,IKBKB,ADCK4,CPSF3,MET,CDK12,ACSL5,SEC24A,PRAME,BRD4,PDK1,COL5A2,EIF3J,RAB7A,SATB2,STK10,FGFR1,PUSL1,FBXL5,CAMK2D,HIPK2,SLC4A7,RPS6KB1,MDN1,SMG1,BCKDK,TNIK,BRAF,ESCO1,MAP3K13,CAMK1,TCF3,TRIM22,CSNK1A1,GIGYF2,PRKCH,ABL1,CLK2,RPS6KB2,TTLL5,TEX14,FERMT2,CTIF,OXSR1,INF2,NSD1,TRIB3,NME1-NME2,ATM,RBPJ,ADK,RPS6KC1,BRWD3,ZAK,MMP16,STK4 |
| 1.427e-03 | -6.55 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 797 | 131 | 17775 | 2278 |
IMMP2L,LETM1,NF1,POLR1A,TRPM6,CSNK2A1,STK33,PRKCA,NBEAL1,MAP2K3,ABL2,PDZD2,NEK6,THADA,CDK6,PRKACB,SRPK2,TNK2,NRAS,NR6A1,CDK4,TCEB3,KSR2,BRCA1,SGK2,BSN,DYRK1B,MSRA,TRRAP,VPS13D,RIOK1,BMI1,FN1,TAF1,CLK1,TRIO,CENPB,PIK3R4,TGFBR2,ARID1B,PRKCE,SEMA3D,MAP3K12,SAMD3,SIK3,CAMKK2,LAMC1,TRA2A,OBSCN,SYT1,USP46,IRS1,GRIK4,KIDINS220,SYNCRIP,SPEN,DNAH17,RIOK3,PDLIM5,TBCK,MAP2K4,DMXL2,SYT17,PCNT,ARID2,PDK4,DDR2,COBLL1,RIPK1,STAM,RIOK2,CAD,PRKD3,UBR1,RPS6KL1,PPFIBP1,IKBKB,ADCK4,CPSF3,MET,CDK12,ACSL5,SEC24A,PRAME,BRD4,PDK1,COL5A2,EIF3J,RAB7A,SATB2,STK10,FGFR1,PUSL1,FBXL5,CAMK2D,HIPK2,SLC4A7,RPS6KB1,MDN1,SMG1,BCKDK,TNIK,BRAF,ESCO1,MAP3K13,CAMK1,TCF3,TRIM22,CSNK1A1,GIGYF2,PRKCH,ABL1,CLK2,RPS6KB2,TTLL5,TEX14,FERMT2,CTIF,OXSR1,INF2,NSD1,TRIB3,NME1-NME2,ATM,RBPJ,ADK,RPS6KC1,BRWD3,ZAK,MMP16,STK4 |
| 1.430e-03 | -6.55 | V$STAT1_02 | MSigDB lists | V$STAT1_02 | 243 | 48 | 17758 | 2279 |
CHMP2A,MPI,PRPF38B,ISG20L2,CSNK1A1,GABPB2,POGZ,SH2B3,TTC1,RGS17,SRSF2,SHC1,PI4KB,VGF,ALKBH8,POLR1B,ADCK4,AGL,CDK6,PRKACB,PRPF19,BDNF,HMBOX1,NRAS,TSTA3,MON1A,NR6A1,ZNFX1,MEX3B,MARS,SOX4,SYMPK,UBR4,C19orf70,TJAP1,RDH11,TMCO1,SLC30A3,IKZF4,RPL28,TIMM17A,SET,CAMKMT,INTS9,FTSJ1,ZRANB2,PREPL,LRRC41 |
| 1.433e-03 | -6.55 | JIANG_HYPOXIA_NORMAL | MSigDB lists | JIANG_HYPOXIA_NORMAL | 300 | 57 | 17758 | 2279 |
IMMP2L,CDCP1,AK2,MVK,ANKRD17,MFGE8,SLC2A1,MYH9,ZFP36L1,IGF2BP2,ATF7IP,NOL3,FOSL2,IKBIP,EIF2S2,NEK6,STC2,ANAPC10,VAPB,CORO1A,SRRM2,SERBP1,NT5E,PFKFB4,PEA15,SLC3A2,SESN2,DDX41,LAMC1,NARS,STAMBP,UPP1,KCNMA1,HSPA5,LGALS1,PTPN12,AKAP12,MCL1,CAV1,KLF6,SERGEF,SAP30BP,ANGPTL4,ARIH2,UBE2E1,PLIN2,HIF1A,CFD,SQLE,XPNPEP1,DPP4,ITGB4,PTP4A2,DHCR7,SMG1,RNF114,NIT1 |
| 1.437e-03 | -6.55 | DNA Replication | WikiPathways | WP466 | 42 | 13 | 4455 | 564 |
RFC4,MCM10,RFC3,MCM6,POLE2,PRIM2,POLA1,MCM5,ORC5,DBF4,MCM2,UBC,RPA1 |
| 1.443e-03 | -6.54 | Q_MOTIF | prosite domains | PS51195 | 37 | 12 | 11866 | 1504 |
DDX3X,DDX28,DDX56,DDX50,DDX41,DDX24,DDX18,DDX19A,EIF4A2,DDX31,DDX10,DDX49 |
| 1.455e-03 | -6.53 | MORF_CDC16 | MSigDB lists | MORF_CDC16 | 72 | 19 | 17758 | 2279 |
MYCBP2,DEAF1,AK2,CAMKK2,SKIV2L2,NPM3,DDX19A,XPO7,DKC1,MBNL1,ARIH2,POM121,CDC16,SMARCC1,HNRNPR,CBR4,TNPO3,RBPJ,YARS |
| 1.462e-03 | -6.53 | MTA2 (metastasis associated 1 family member 2) | protein interactions | 9219 | 101 | 26 | 16036 | 2270 |
GATAD2B,PCNT,GPHN,KDM5B,SIRT6,SMARCAD1,SIRT7,SATB2,BRCA1,CHD5,FKBP3,KDM1A,POLR2A,CHD7,SPAG9,TP53BP1,HNRNPR,CHD3,MBD2,SPEN,BANF1,RNF2,BRCC3,SRRM2,HNRNPM,SAP30 |
| 1.473e-03 | -6.52 | negative regulation of mRNA polyadenylation | biological process | GO:1900364 | 8 | 5 | 16441 | 2138 |
RNF40,CTR9,SUPT5H,CCNT1,CDK9 |
| 1.473e-03 | -6.52 | cellular response to hyperoxia | biological process | GO:0071455 | 8 | 5 | 16441 | 2138 |
CAV1,FOXO1,EGR1,PPARG,ATG7 |
| 1.473e-03 | -6.52 | cellular response to increased oxygen levels | biological process | GO:0036295 | 8 | 5 | 16441 | 2138 |
CAV1,FOXO1,EGR1,PPARG,ATG7 |
| 1.475e-03 | -6.52 | TRNA_METABOLIC_PROCESS | MSigDB lists | TRNA_METABOLIC_PROCESS | 19 | 8 | 17758 | 2279 |
METTL1,POP1,SARS,RARS,FARS2,YARS,AARS,WARS |
| 1.476e-03 | -6.52 | BERENJENO_TRANSFORMED_BY_RHOA_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_DN | 378 | 69 | 17758 | 2279 |
ASCC1,CHMP2A,ATP6V1A,PDK4,ENAH,GRINA,SIRT2,SSBP2,LPIN1,DECR1,SHC1,SLC38A2,MMP14,GSTA4,TTC3,NDUFA6,MEIS3,MCEE,LAMA4,LIMA1,WLS,PTPRM,ATG12,ATP6V0A1,AKAP12,SEMA3F,CAV1,GALK2,LAMA2,ST3GAL5,FGFR1,OSBPL1A,VDR,IFT81,TCF7L1,LSS,PER1,SYNPO,AOC3,FN1,CLK1,CCDC53,TRIO,ID2,HES6,GAS6,BHLHE40,LYRM2,FAM8A1,PCK2,AMOT,ATP6V0D1,SPTAN1,USE1,TSPYL4,MYO10,RABAC1,CPT1A,ECH1,SEC31A,EPRS,FSCN1,COQ9,ZFP90,DTD1,ZNF32,PSAP,DHCR7,DDIT3 |
| 1.491e-03 | -6.51 | Zinc_finger_PHD-type_CS | interpro domains | IPR019786 | 67 | 18 | 18293 | 2341 |
ASH1L,PHF3,KDM5B,KMT2E,KDM5A,NFX1,RSF1,CHD5,TRIM66,MLLT10,BAZ1A,NSD1,KDM2A,TAF3,CHD3,INTS12,KDM5C,FBXL19 |
| 1.493e-03 | -6.51 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 916 | 151 | 16491 | 2164 |
POLB,MVK,PRKAB2,POLR1A,TRPM6,CSNK2A1,STK33,PRKCA,MAP2K3,ABL2,NEK6,PHKA1,POLR3B,POLE3,ZNRD1,CDK6,PRKACB,SRPK2,TNK2,CDK4,COL4A3BP,KSR2,KCNH2,SGK2,DYRK1B,TRRAP,CRCP,RIOK1,NRP1,SEPHS2,CTU2,XYLB,TTN,PIGN,AK2,CLK1,TAF1,SLK,AK6,TRIO,PIK3R4,TGFBR2,PRKCE,PI4KB,ISPD,PIGG,GTF2H1,ALDH18A1,MAP3K12,POLR1E,N4BP2,PRPS1,GTF2H3,SIK3,CAMKK2,PRIM2,POLA1,OBSCN,MYBBP1A,NME7,CDK9,IRAK2,RIOK3,ZCCHC6,HK2,CASS4,TBCK,BRSK2,MAP2K4,MAP2K5,PAPD4,PDK4,DDR2,RIPK1,RIOK2,CAD,FLAD1,PRKD3,SHC1,RPS6KL1,FGGY,IKBKB,CMPK1,ADCK4,MET,PXK,CDK12,PDK1,PI4KAP2,DLG4,GALK2,KCNH3,AKAP13,DKC1,POLG2,STK10,FGFR1,TPK1,TAMM41,CAMK2D,HIPK2,POLR3E,HSPB8,RPS6KB1,MED20,EIF2B3,SMG1,HMGA2,BCKDK,TNIK,BRAF,MINK1,MAP3K13,CAMK1,TKFC,IP6K2,TGFB2,CSNK1A1,RPS6KA5,PIP4K2A,ABL1,PRKCH,NPRL2,POLR3D,POLR1B,MAP3K14,RPS6KB2,CLK2,PFKFB4,GPHN,POLK,CRIM1,TEX14,TBRG4,PTK2,OASL,PPIP5K2,PEAK1,PIK3CB,POLR3A,POLR2A,POLR3G,OXSR1,TRIB3,POLE2,ATM,POLR1C,ADK,RPS6KC1,ZAK,STK4 |
| 1.495e-03 | -6.51 | DOANE_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_DN | 231 | 46 | 17758 | 2279 |
EFNB2,PTP4A1,PPDPF,CDC42EP2,SUPT6H,RIBC2,PRAF2,PDE4B,MED13L,ID2,KIF5C,SSBP2,NUP160,PHLDA2,RTN1,DST,MCAM,MCM5,LPIN2,SERPINH1,EVL,TRA2A,ELOVL6,WLS,CPOX,ASAP3,TBRG4,ATXN1,TMEM123,SEMA3F,PALLD,SLC35D1,PLCB1,DSP,NCDN,NR2F1,RAD54B,CHAF1A,TAF9B,ATP5D,VDR,IRS1,SMAD3,SEMA3C,BLMH,PTPN14 |
| 1.496e-03 | -6.50 | GAVIN_FOXP3_TARGETS_CLUSTER_T7 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T7 | 94 | 23 | 17758 | 2279 |
USE1,DCTN3,PPDPF,MCM6,RBM33,PSTPIP2,LGALS1,RAP1GDS1,VIM,REEP5,ECH1,EIF3H,FAM50A,ALG5,SUPT4H1,ATP5G2,FIS1,GSTA4,PTP4A2,PRPS1,LONP1,MTHFD1,CDC37 |
| 1.500e-03 | -6.50 | VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor) | protein interactions | 7421 | 96 | 25 | 16036 | 2270 |
NCOR2,MMRN2,PPARG,PRKCSH,KDM5A,TCF3,NKD2,POU2F1,CSNK2A1,MED16,BRCA1,FOXO3,POLR2A,SMAD3,VDR,NSD1,SNW1,HR,CLASRP,MYC,MED24,NCOR1,RUNX1,NRIP1,BAG1 |
| 1.500e-03 | -6.50 | purine nucleobase metabolic process | biological process | GO:0006144 | 41 | 13 | 16441 | 2138 |
CAT,HPRT1,AMPD3,GART,PPAT,ATIC,ADSL,NT5C,APRT,IMPDH2,ADK,PRPS1,NT5E |
| 1.501e-03 | -6.50 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 578 | 99 | 17758 | 2279 |
CYP24A1,PTP4A1,ZNF292,SYT17,PHF3,C16orf45,MRPL10,RSL1D1,CCNL2,IKBIP,ZNF44,FOSL2,FAM13A,SLC6A8,SEC16A,ABHD6,SEMA6A,PAG1,LPAR3,PABPC4,PCDH7,SHC1,GLYR1,IKBKB,TTC3,LYRM5,MCEE,PDK1,ZNF680,GPCPD1,TFPI,ARRDC3,HSPA5,PNN,MARCH6,KRTCAP2,ZNF91,TTC28,CXADR,TAF9B,PLIN2,KDM4B,ITGA2,AHNAK2,PAM,SGSM2,ABCC3,TNFRSF10D,FAM118A,BAG1,EPM2AIP1,AUH,MAP3K13,SEC24D,CLK1,B4GALT5,PDE4B,LETMD1,WDR37,C11orf54,SLC1A1,ARID1B,NAMPT,TOX4,FKBP1A,GART,HAS3,IFIT5,NISCH,STC2,SHMT2,GMDS,PCSK6,ADARB1,CAMKK2,KDM5B,RB1CC1,TRA2A,FOXN3,ARID5B,ZNF512B,FOXC1,HERPUD1,RERE,SEC31A,CAT,RPL28,ACOX1,D2HGDH,HK2,RRAGA,ZRANB2,TBL1X,RBPJ,IQSEC2,IGBP1,TESC,N4BP2L2,RNF114 |
| 1.502e-03 | -6.50 | ATGTACA,MIR-493 | MSigDB lists | ATGTACA,MIR-493 | 307 | 58 | 17758 | 2279 |
ZNF706,TTN,SPRED2,SSH2,PRPF38B,FOXO1,ANKRD17,C16orf45,MED13L,GTF2IRD1,COBLL1,ENAH,ZIC2,BCOR,XPO7,CSNK1A1,RPS6KA5,GBF1,ARID1B,CDC73,ZNF804A,SH2B3,SIPA1L3,UBE3A,NBEA,ETF1,NLGN3,LPCAT1,FMNL2,CARM1,MAML3,SRPK2,KDM5B,WDFY3,BAZ2A,C19orf43,KCNMA1,PREX1,PTPN12,RSBN1,MCL1,ARID1A,MBNL2,MLLT10,DDX3X,EIF4ENIF1,LSM14A,SPEN,HIC2,VPS13D,SVIL,CNOT6,ZBTB11,KIF1B,SLC25A26,ZNF532,SMG1,MEF2C |
| 1.505e-03 | -6.50 | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDM_UP | 194 | 40 | 17758 | 2279 |
PPDPF,POLB,TRIP6,UPK3B,DLGAP4,PPP2R2A,PBX1,RLF,CUTC,MBNL1,BZW2,FAM192A,ATG3,WAC,SELT,PLEKHA2,KDM3B,CLYBL,TBXAS1,TCEB3,COL4A3BP,AKAP12,VIM,BRCA1,UBR4,UBC,TAMM41,KLHL22,RARS,RBBP8,PDLIM1,HIPK2,VCAN,PER1,MBTD1,ARHGAP12,MBD6,APAF1,PKIB,STK4 |
| 1.505e-03 | -6.50 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | 194 | 40 | 17758 | 2279 |
FEM1C,EIF3C,UTP14A,PRKCSH,SF3A3,TUBB6,PLEK2,FOXP1,AARS,HSPA1A,RHBDD1,AHCYL2,KDM1A,SBDS,ATXN7L1,KIAA1958,ASNS,NSRP1,SCN1B,ZEB1,RNF2,YARS,TIMM50,MPP6,SLC38A1,RSBN1,ENC1,CRYBG3,PLCXD2,ZNF655,HSPA1B,PYCR1,ZC3H12A,ADAT2,TBPL1,CASS4,TBL1X,ANXA2,POLR1C,NAPA |
| 1.505e-03 | -6.50 | GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN | MSigDB lists | GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN | 194 | 40 | 17758 | 2279 |
UNC13D,SEPHS2,SSH2,RAB11FIP4,TRIP6,TRIM16,SEC24D,TRPM6,RTN4,SPATS2L,SEMA6A,TMCO6,SKI,RNF141,RGS17,SYN2,STC2,ZNF142,SHMT2,SETD1B,TSTA3,TMEM126A,TOP3A,PEAR1,PLEKHM3,TRAPPC6B,SLC26A11,S100A16,PUSL1,WARS,YIPF2,ZNF557,SDCCAG8,TBX3,TSSC1,ZNF430,USP11,RNF214,TMEM158,TRIM36 |
| 1.507e-03 | -6.50 | positive regulation of viral process | biological process | GO:0048524 | 104 | 25 | 16441 | 2138 |
ADARB1,GTF2H3,CHMP2A,RAB7A,TCEB3,LGALS1,SMARCA4,RSF1,NELFA,SUPT5H,POLR2A,SMARCB1,DDX3X,ELL,SNW1,SUPT4H1,CCNT1,PPID,CDK9,VPS37B,GTF2H1,VAPB,NCBP2,CHMP4C,SRPK2 |
| 1.519e-03 | -6.49 | Signaling events mediated by HDAC Class I | Pathway Interaction DB | hdac_classi_pathway | 66 | 19 | 2227 | 319 |
GATAD2B,NCOR2,TFCP2,PPARG,SIRT6,SIRT7,SMAD7,RANGAP1,HDAC8,SIRT2,FKBP3,RANBP2,CHD3,MBD2,TNFRSF1A,RAN,NCOR1,PRMT5,SAP30 |
| 1.521e-03 | -6.49 | GSE360_DC_VS_MAC_UP | MSigDB lists | GSE360_DC_VS_MAC_UP | 188 | 39 | 17758 | 2279 |
USP7,CAMK1,WDR37,ISG20L2,PHLDA2,MAN1A1,WNT2B,ZNF804A,NPRL2,SIPA1L3,RAP1A,IFIT5,FMNL1,HARS2,GREB1,LARP4B,PRMT3,PXN,ZNF124,TUBA1A,ITPA,MARCKSL1,LIG4,RSBN1,CA5B,MBNL2,UBR4,MAT2A,BSN,GLS,CACNB1,BRCA2,KIDINS220,ACOX1,CCDC85B,TPM1,RABEP1,STK4,LPP |
| 1.521e-03 | -6.49 | GSE17721_PAM3CSK4_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_4H_BMDM_UP | 188 | 39 | 17758 | 2279 |
EFNB2,NCOR2,FAM207A,TCF3,LAMTOR3,ZFP36L1,APRT,IKBKAP,AARS,FAM50A,SACS,ZKSCAN1,NISCH,TNPO3,ARHGAP1,RAN,TSPAN14,TMEM120B,TMEM14C,PEA15,IFRD1,ATF4,IFNGR2,PPP1R21,MEF2D,FAM126B,MARCH6,COTL1,MAK16,MAT2A,ARIH2,BATF3,LSS,VPS13C,HNRNPH3,RIOK3,H2AFX,TMEM101,C12orf45 |
| 1.525e-03 | -6.49 | HDAC2 (histone deacetylase 2) | protein interactions | 3066 | 297 | 61 | 16036 | 2270 |
EP400,NCOR2,ESCO1,CUL7,TCF3,SIRT7,SMAD7,CSNK2A1,SMARCA4,CHD5,PELP1,KDM1A,SMARCB1,PHC2,SNW1,HR,MBD2,MYC,BANF1,MAD1L1,WIZ,RNF2,KDM5C,SERPINH1,NRIP1,SRRM2,ZMYM2,SAP30,GATAD2B,IFRD1,APEX1,RREB1,KDM5B,NARS,SIRT6,TFCP2,KDM5A,SMARCAD1,EHMT1,ARID5B,PRDM1,BRCA1,MEN1,SRA1,FKBP3,POLR3A,RERE,IRS1,DNTTIP1,KPNA1,IKZF4,EHMT2,HIF1A,CHD3,SPEN,KLF4,TBX3,CRCP,RUNX1,RBP1,EMSY |
| 1.526e-03 | -6.49 | Arachidonate production from DAG | REACTOME pathways | R-HSA-426048 | 5 | 4 | 8202 | 1117 |
DAGLA,DAGLB,MGLL,ABHD6 |
| 1.530e-03 | -6.48 | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | 511 | 89 | 17758 | 2279 |
VMA21,KCTD7,CGN,LPCAT2,PSTPIP2,UROD,HECTD3,SLC25A21,PPIL1,ST7L,SLC29A1,CHAC1,LTB4R,DHX35,RPAIN,PHF5A,ERI1,RABGAP1L,ETF1,BCAP29,PRADC1,MET,HCFC2,TRMT12,TMEM14C,LYST,SEH1L,CSGALNACT2,SAP30,RNMT,ITPA,RAB7A,CPOX,TMEM216,PITPNB,MTHFD1L,MCM2,CXADR,PLIN2,BAZ1A,ALAD,G6PD,HSPBAP1,CAMKMT,WDR7,FTSJ1,RNF130,GALNT10,ANXA2,NRP1,TMEM33,INSIG2,CLDN15,AUH,ZCCHC8,XRRA1,ALG8,LAMTOR3,RNASEH2B,CLINT1,SPIRE1,MTUS1,NDUFV1,HVCN1,GATC,SLC38A5,ASAP1,PLEKHA2,SERBP1,C12orf4,LRRC20,WDR61,XPO5,MRPS10,USP46,CENPP,ATP9B,EXOC6,ATAD5,TASP1,KPNA1,UBAP1,SDCCAG8,FDPS,MYOM2,HMBS,NAPA,MAP2K4,KIF1B |
| 1.535e-03 | -6.48 | ACCTGTTG_UNKNOWN | MSigDB lists | ACCTGTTG_UNKNOWN | 146 | 32 | 17758 | 2279 |
CHST11,SYT17,JUP,SEC24D,NPAS2,SESTD1,RNF43,CSNK1A1,FOXO3,MAN1A1,MTUS1,DST,NRF1,ZFHX3,SAMD11,CCDC112,SHF,TSPAN14,YARS,MSI2,LAMA4,KCNQ3,ZC3H18,WDPCP,ATXN1,UBE2E1,SNCA,DDAH2,EPN2,ATAD5,ARL4A,MMP16 |
| 1.535e-03 | -6.48 | tRNA methylation | biological process | GO:0030488 | 23 | 9 | 16441 | 2138 |
METTL1,TRMT5,TRMT13,TRMU,ALKBH8,METTL2A,FTSJ1,TRMT10A,METTL2B |
| 1.535e-03 | -6.48 | regulation of transcription elongation from RNA polymerase II promoter | biological process | GO:0034243 | 23 | 9 | 16441 | 2138 |
PAF1,ELL,BRD4,SUPT4H1,WDR61,SUPT6H,CTR9,NELFA,CDC73 |
| 1.535e-03 | -6.48 | positive regulation of G1/S transition of mitotic cell cycle | biological process | GO:1900087 | 23 | 9 | 16441 | 2138 |
DDX3X,CUL4A,ANKRD17,PLRG1,RDX,PPP1R1C,PLCB1,LSM10,ANXA1 |
| 1.535e-03 | -6.48 | GSE17721_CTRL_VS_POLYIC_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_6H_BMDM_UP | 182 | 38 | 17758 | 2279 |
XPC,FAM189B,UBXN1,LAMTOR3,SPATS2,ZNF346,TTI1,SSR4,SEC16A,SCAF8,RAP1A,SPG21,APLF,UBR1,ZDHHC6,BCAP29,ANP32B,TSPAN14,VOPP1,DDX41,ELOVL6,ARHGAP39,ATG12,RNH1,SUPT5H,EVI5,EIF3H,NEU1,ECH1,PGD,UBAP1,SRP68,MPV17,FTSJ1,MACROD1,USP11,ECHDC1,TMEM141 |
| 1.535e-03 | -6.48 | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDM_DN | 182 | 38 | 17758 | 2279 |
PTCD2,CUL4A,DDX18,ZCCHC8,SEC24D,SLC2A1,MYO7A,HES6,CD99L2,ATG2B,IKBKAP,PAG1,WNT2B,EXOC1,POLR3D,NDRG4,TTC3,ANP32B,MAP3K14,PRMT5,HSD17B12,CLK2,SF3A1,FAM98A,LDHA,USP10,MEF2D,GPNMB,EVI5,VAC14,NEU1,YIF1A,SMARCC1,TBPL1,GPN1,C12orf45,SGSM3,NR2C2AP |
| 1.536e-03 | -6.48 | single-organism biosynthetic process | biological process | GO:0044711 | 1365 | 214 | 16441 | 2138 |
GGT1,PIGM,MVK,CUL4A,DPH1,RARS2,PPARGC1B,PRKAB2,AARS2,MRPL10,CERS5,CACNA1H,RCHY1,PLOD1,GYG1,COX10,SYNJ1,LPIN1,MRPS30,AMPD3,ATP5G2,PPCDC,HYAL1,ME1,DPH6,SLC27A5,FXN,PRKACB,CSGALNACT2,GCNT2,ATF4,HARS,UPP1,GPCPD1,COL4A3BP,MTHFD1L,BRCA1,PITPNB,ODC1,ST3GAL5,MGST1,STOML2,PYCR1,GLS,LSS,HPRT1,INSIG1,RAD18,BDH2,RBP1,SEPHS2,XYLB,AK2,PIGN,CHST11,ST6GAL1,GPAT3,PIK3R4,ALG8,DPM3,PLA2G12A,PHGDH,YARS2,NAMPT,PI4KB,ATIC,ISPD,PIGG,VAPB,SYNJ2,ALDH18A1,MRPL21,PNPLA3,LPCAT1,AGL,COQ3,PRPS1,TERF2,FDFT1,NT5E,MTHFD1,HMGCR,FADS1,ALG6,PRIM2,PPAT,ELOVL6,POLA1,RDH10,TBXAS1,USP10,ST6GALNAC3,IMPDH2,MTR,VAC14,ISG15,PGD,MGAT2,MTHFD2,GSTO2,NME7,VCAN,FDPS,SURF1,TBPL1,SQLE,UMPS,HMBS,CNDP2,GGT7,DHCR7,PDSS2,HS2ST1,MPI,TRERF1,SUCLG1,LPCAT2,CEMIP,SLC2A1,UROD,GPR143,PIGH,PBX1,LPCAT3,ST3GAL6,TNKS1BP1,LCLAT1,FDX1,TERF2IP,FLAD1,CAD,IDI1,ASNS,CBR4,PYCRL,LPIN2,MRPS27,GSTA4,CMPK1,SERPINH1,MTHFD2L,MGLL,TMEM14C,TMLHE,PRPF19,ACSL5,RFC4,GARS,RFC3,MTIF2,CPOX,MRRF,ATP6V0A1,SLC35D1,DKC1,HSD3B7,MAT2A,ATP5D,TAMM41,ALAD,DCXR,G6PD,PEMT,ABHD3,LARGE,SLC25A11,SERINC5,INSIG2,B4GALT5,C10orf2,MRI1,SLC25A12,APRT,CHCHD10,LIAS,PIP4K2A,GFM2,MAD2L2,MRPS11,PEX7,GART,GATC,HAS3,ACOT11,HARS2,PTGS1,SHMT2,CPNE7,PCK2,HSD17B12,SLC25A1,APEX1,PSAT1,FGF2,POLK,AGPAT4,MRPS10,ADSL,PIK3CB,MMAA,NEU1,UBC,MRPL36,RPA1,ALG5,SERINC1,POLE2,GPC2,COQ9,SRD5A3,ATM,GPAM,MTMR1,ADK |
| 1.536e-03 | -6.48 | purine nucleoside monophosphate biosynthetic process | biological process | GO:0009127 | 61 | 17 | 16441 | 2138 |
AK2,PPAT,ATP6V0A1,ADSL,APRT,CHCHD10,IMPDH2,ATP5D,STOML2,AMPD3,HPRT1,GART,ATP5G2,ATIC,SURF1,ADK,PRPS1 |
| 1.536e-03 | -6.48 | purine ribonucleoside monophosphate biosynthetic process | biological process | GO:0009168 | 61 | 17 | 16441 | 2138 |
AK2,PPAT,ATP6V0A1,ADSL,APRT,CHCHD10,IMPDH2,ATP5D,STOML2,AMPD3,HPRT1,GART,ATP5G2,ATIC,SURF1,ADK,PRPS1 |
| 1.536e-03 | -6.48 | RNA polymerase I regulatory region sequence-specific DNA binding | molecular function | GO:0001163 | 8 | 5 | 16491 | 2164 |
SMARCA4,UBTF,RRN3,BAZ2A,SMARCB1 |
| 1.536e-03 | -6.48 | RNA polymerase I CORE element sequence-specific DNA binding | molecular function | GO:0001164 | 8 | 5 | 16491 | 2164 |
SMARCA4,UBTF,RRN3,BAZ2A,SMARCB1 |
| 1.542e-03 | -6.47 | AMP metabolic process | biological process | GO:0046033 | 15 | 7 | 16441 | 2138 |
ADSL,APRT,AMPD3,AK2,ADK,PRPS1,NT5E |
| 1.545e-03 | -6.47 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP | 176 | 37 | 17758 | 2279 |
ADAM19,BCAS4,FOXO1,TTC27,ST6GAL1,TCF3,ZNF107,DCTPP1,CAD,CHD7,ASNS,ATIC,ZNF85,NOC3L,ALDH18A1,FBL,PRPS1,HTRA2,CTC1,RFC4,ARID5B,GNG7,C11orf80,ATF7IP2,ODC1,ZBTB25,PWP1,PDLIM1,TP53BP1,POLR3E,PTPN4,PPP3CC,MDN1,CCNB1IP1,NOLC1,ADK,SMYD3 |
| 1.545e-03 | -6.47 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 176 | 37 | 17758 | 2279 |
SERINC5,PRPF38B,ZNF516,UBN1,KIAA0232,ATG2B,XPO7,IKBKAP,SLC25A44,ST3GAL6,TIGD1,TGFBR2,LCLAT1,ZMAT2,SLC25A20,HVCN1,SLC38A2,NT5C,ZNF518B,FDFT1,RPS6KB2,SLC40A1,DDX28,RFC3,TSPYL4,TOP3A,RABAC1,PDE3B,PGD,G6PD,HERC1,ABHD3,PTRH2,TMEM219,CNOT6,STK4,RNF114 |
| 1.551e-03 | -6.47 | PABPC1 (poly(A) binding protein, cytoplasmic 1) | protein interactions | 26986 | 222 | 48 | 16036 | 2270 |
SART1,CUL7,CUL4A,FN1,DDX19A,PLRG1,SIRT7,AGO2,MEX3A,NFX1,PCSK7,PHGDH,UBR5,GIGYF2,PAIP2,SNW1,RPS16,ATXN2,ETF1,PABPC1,CARM1,SERBP1,CLK2,SRPK2,SF3A1,MSI2,SNU13,PXN,APEX1,SKIV2L2,EIF4A2,USP10,MEX3B,BRCA1,CHAF1A,RPA1,SMAD3,SYNCRIP,HNRNPR,COPS5,FDPS,CUL2,H2AFX,CNOT6,COPS6,IGBP1,SMG1,TNRC6A |
| 1.553e-03 | -6.47 | PolyA | smart domains | SM00517 | 5 | 4 | 9131 | 1249 |
PABPC1L,UBR5,PABPC1,PABPC4 |
| 1.554e-03 | -6.47 | HIST1H2BA (histone cluster 1, H2ba) | protein interactions | 255626 | 86 | 23 | 16036 | 2270 |
EP400,MCM6,GON4L,XPC,PARP2,ARID5B,EHMT1,HLTF,HIST1H2BL,MCM2,PELP1,HIST2H2AB,SRCAP,TRRAP,EHMT2,APLF,CFDP1,VPS72,SET,MBTD1,SENP3,ANP32B,CRAMP1 |
| 1.561e-03 | -6.46 | regulation of metaphase/anaphase transition of cell cycle | biological process | GO:1902099 | 46 | 14 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,NEK6,NSMCE2,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 1.581e-03 | -6.45 | RNA_helicase_DEAD_Q_motif | interpro domains | IPR014014 | 37 | 12 | 18293 | 2341 |
DDX3X,DDX28,DDX56,DDX50,DDX41,DDX24,DDX18,DDX19A,EIF4A2,DDX31,DDX10,DDX49 |
| 1.586e-03 | -6.45 | SUMOylation | REACTOME pathways | R-HSA-2990846 | 79 | 21 | 8202 | 1117 |
HERC2,STAG1,XPC,SCMH1,SUMO3,BRCA1,NUP43,NUP214,NUP160,RING1,POM121,RPA1,PHC2,RANBP2,NUP133,NSMCE2,NSMCE1,RNF2,XRCC4,BMI1,SEH1L |
| 1.588e-03 | -6.45 | UPF1 (UPF1 regulator of nonsense transcripts homolog (yeast)) | protein interactions | 5976 | 112 | 28 | 16036 | 2270 |
EXOSC2,NIFK,FN1,TRA2A,SIRT7,SMARCA4,SMG7,PARN,POLR2A,EDC3,POP1,EIF2S2,SYNCRIP,HNRNPR,COPS5,EIF2S1,ATM,ETF1,NCBP2,RNF2,UPF2,FUS,EXOSC4,BMI1,ZC3H3,PABPC1,SMG1,CDC37 |
| 1.604e-03 | -6.44 | alpha-amino acid biosynthetic process | biological process | GO:1901607 | 77 | 20 | 16441 | 2138 |
SEPHS2,GGT1,PSAT1,MRI1,PLOD1,MTHFD1L,PHGDH,MTR,PYCR1,GLS,CAD,MTHFD2,ASNS,GART,PYCRL,ATIC,SHMT2,ALDH18A1,MTHFD2L,MTHFD1 |
| 1.604e-03 | -6.44 | organic acid metabolic process | biological process | GO:0006082 | 1002 | 162 | 16441 | 2138 |
GGT1,RARS2,PRKAB2,AARS2,SLC25A21,PLOD1,SLC6A8,AARS,AHCYL2,LPIN1,PCYOX1L,FAAH2,PPCDC,HYAL1,SUCLG2,ME1,SLC27A5,YARS,PPM1K,MPST,CSGALNACT2,ACADS,SESN2,ATF4,PPARG,HARS,ALDH1L2,BRCA1,MTHFD1L,DLST,ODC1,ST3GAL5,MPC1,PYCR1,GLS,MSRA,DDAH2,HLCS,BDH2,TNFRSF1A,ABCC3,SPOCK2,SPOCK3,RBP1,SEPHS2,XYLB,CARS,SARS,CHST11,LARS2,ST6GAL1,HSD17B10,PLA2G12A,PHGDH,YARS2,ETFB,ATIC,SLC16A9,ALDH18A1,PPA1,PRPS1,MTHFD1,FADS1,WARS2,PPAT,ELOVL6,PCCA,RDH10,IDH3G,TBXAS1,CPT1A,ACOXL,MTR,PGD,DAGLA,EPRS,MTHFD2,GSTO2,HIF1A,VCAN,D2HGDH,HK2,SLC16A1,DPEP1,DTD1,PEX13,BPNT1,GGT7,CNDP2,HS2ST1,CPT1C,SDSL,SUCLG1,SLC2A1,UROD,PDK4,TNXB,LPCAT3,ST3GAL6,CAD,FARSA,DECR1,ASNS,CBR4,PYCRL,LPIN2,HIBCH,AHCYL1,MTHFD2L,MGLL,TMLHE,ACSL5,MCEE,NARS2,GARS,PDK1,NARS,SLC35D1,HSD3B7,WARS,SNCA,DCXR,PEMT,ATG7,MORC2,DMGDH,SERINC5,BCKDK,AUH,SULT1C2,B4GALT5,MRI1,FARS2,VARS,LIAS,PEX7,GART,GATC,ACOT11,HARS2,SHMT2,PTGS1,PHYKPL,HSD17B12,LYPLA2,PFKFB4,PSAT1,LDHA,SULT4A1,MARS,MMAA,TARS,ECH1,SLC23A2,ETFDH,RARS,GPC2,SERINC1,DAGLB,ACOX1,GPAM,GCSH |
| 1.619e-03 | -6.43 | DNA_REPAIR | MSigDB lists | DNA_REPAIR | 123 | 28 | 17758 | 2279 |
PMS1,RFC3,APEX1,XPC,ATRX,POLA1,LIG4,BRCA1,APTX,MLH1,RPAIN,RAD54B,RPA1,EXO1,ABL1,BRCA2,RBBP8,GADD45A,POLE2,XRCC2,MSH3,RAD51B,ALKBH1,ATM,GTF2H1,XRCC4,OGG1,MUTYH |
| 1.620e-03 | -6.43 | BILANGES_SERUM_SENSITIVE_VIA_TSC2 | MSigDB lists | BILANGES_SERUM_SENSITIVE_VIA_TSC2 | 37 | 12 | 17758 | 2279 |
EIF3C,GON4L,CRIM1,NPM3,GLG1,SMARCA4,TBC1D16,EIF5B,GBF1,KIF1B,C7orf26,NEDD4 |
| 1.629e-03 | -6.42 | AGCTCCT,MIR-28 | MSigDB lists | AGCTCCT,MIR-28 | 89 | 22 | 17758 | 2279 |
SSH2,GPM6A,NRAS,LUZP1,CRIM1,LSM12,FOXN3,C16orf52,RAP1B,ATXN1,ARID1A,MEF2D,MAT2A,SMAD3,IKZF4,KIAA0355,BIVM,KDM5C,IQSEC2,HTRA2,SEH1L,KAT6A |
| 1.629e-03 | -6.42 | MORF_PPP5C | MSigDB lists | MORF_PPP5C | 89 | 22 | 17758 | 2279 |
EP400,SPRED2,SIGMAR1,ATRX,KIAA0586,KLHL18,BRCA1,TTI1,EIF5B,HTR7,TAF2,RAP1A,SLC30A3,RBBP8,CHD3,MSH3,FNTB,SLC25A11,SYNJ2,NFRKB,MUTYH,RPS6KB2 |
| 1.636e-03 | -6.42 | Prpf8 (pre-mRNA processing factor 8) | protein interactions | 192159 | 52 | 16 | 16036 | 2270 |
SART1,SNU13,C9orf78,PAXBP1,PRPF31,TTC27,TFIP11,PLRG1,PPIL1,DHX35,RSRC1,NCDN,SNW1,BCAS2,PRPF4,PRPF19 |
| 1.636e-03 | -6.42 | GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase) | protein interactions | 2618 | 52 | 16 | 16036 | 2270 |
CARS,CUL7,PXN,FN1,PPAT,SIRT7,ADSL,SUPT5H,XPO7,WARS,GART,ATIC,SET,HIRIP3,TATDN1,TROVE2 |
| 1.640e-03 | -6.41 | nucleobase-containing compound catabolic process | biological process | GO:0034655 | 349 | 65 | 16441 | 2138 |
LIN28B,PAPD4,DCP1B,RPS29,PPP2R2A,NT5C3A,TNKS1BP1,PDE3A,PABPC4,EDC3,AMPD3,RPS16,ERI1,NT5C,ETF1,OGG1,SKIV2L,SKIV2L2,ITPA,UPP1,NUDT15,PDE8B,HPRT1,NOCT,MUTYH,SMG1,DROSHA,TATDN3,PDE4B,SMG7,ZFP36L1,MLH1,RNASEH2B,PARN,DCTPP1,PDE10A,UPF2,EXOSC4,ERI3,NT5M,CNOT4,PABPC1,NT5E,DIS3L2,EXOSC2,WDR61,PDE4A,EIF4A2,DHX34,RNH1,EXOG,PDE2A,PDE3B,CTIF,POP1,CAT,KPNA1,RPL28,ZCCHC6,ATM,CNOT6,NCBP2,TATDN1,PDE9A,AGO3 |
| 1.640e-03 | -6.41 | positive regulation of viral life cycle | biological process | GO:1903902 | 99 | 24 | 16441 | 2138 |
ADARB1,GTF2H3,CHMP2A,TCEB3,LGALS1,SMARCA4,RSF1,NELFA,SUPT5H,POLR2A,SMARCB1,DDX3X,ELL,SNW1,SUPT4H1,PPID,CCNT1,CDK9,VPS37B,GTF2H1,VAPB,NCBP2,CHMP4C,SRPK2 |
| 1.644e-03 | -6.41 | nucleoside monophosphate metabolic process | biological process | GO:0009123 | 223 | 45 | 16441 | 2138 |
NDUFA5,AK2,ATP6V1A,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,CAD,AMPD3,GART,NDUFV1,ENTPD5,ATP5G2,ATIC,MYH3,CMPK1,NDUFA6,FXN,NT5M,PRPS1,NT5E,PFKFB4,BDNF,PPAT,UPP1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,COQ9,HK2,SURF1,UMPS,NDUFS5,ADK |
| 1.645e-03 | -6.41 | parotid | COSMIC cancer mutations | parotid | 594 | 101 | 17775 | 2278 |
CDCP1,MVK,BIRC6,ATRX,PDK4,CSNK2A1,PRKCA,GBF1,MAP2K3,RPP30,ZNF804A,ABL2,ZNF827,FMNL1,RPS6KL1,GSTA4,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,FLNC,TNK2,NRAS,PDK1,CDK4,CUX1,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,TJAP1,BRCA2,HIPK2,CSMD3,RPS6KB1,TROVE2,PTPN14,HMGA2,SEPHS2,TNIK,AK2,BRAF,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,CCDC7,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,IQGAP2,ABL1,PRKCH,SACS,PI4KB,GTF2H1,ALDH18A1,MAP3K12,TOMM34,RPS6KB2,CAMKK2,RB1CC1,MON1A,CRIM1,MYO10,PRDM16,ARID5B,ARID1A,PALLD,C8orf33,PIK3CB,CENPP,DAGLA,NSD1,SRCAP,TRIB3,LRP1B,FAM135A,DAGLB,HERC1,SPEN,HK2,ATM,CNDP2,PDLIM5,RPS6KC1,MAP2K4,PRKAR2A,DDIT3 |
| 1.655e-03 | -6.40 | negative regulation of sequence-specific DNA binding transcription factor activity | biological process | GO:0043433 | 139 | 31 | 16441 | 2138 |
USP7,ZNF675,RBCK1,ID1,MAP2K5,CYLD,SMAD7,PBX1,ID2,GAS6,BHLHE40,MEN1,TRIM37,MAD2L2,KDM1A,TCF7L2,SPOP,CAT,ZC3H12A,MSX2,HR,SUFU,TAF3,DNAJA3,KLF4,IRAK2,TRAF3,RNF2,SETD6,DDIT3,KAT6A |
| 1.663e-03 | -6.40 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN | 195 | 40 | 17758 | 2279 |
ZNF292,BIRC6,TCF3,SMAD7,WDR26,BHLHE40,HMOX2,EEA1,ANXA10,SFR1,RTN1,PRKD3,IDI1,LDOC1L,TNPO3,OGG1,PRPS1,PRKACB,NUDC,FDFT1,HMGCR,DDX24,CMIP,NPM3,EIF4A2,LRRC8A,FKBP3,STK10,MAT2A,RDH11,ZFP62,EPRS,KPNA1,UBAP2,SET,HOXA3,GPN1,ZRANB2,MED20,NMD3 |
| 1.663e-03 | -6.40 | FUJII_YBX1_TARGETS_DN | MSigDB lists | FUJII_YBX1_TARGETS_DN | 195 | 40 | 17758 | 2279 |
MCM6,MCM10,TRIO,FANCD2,ENAH,MBNL1,MAD2L2,NOP56,MCM5,TIMELESS,VAPB,TRIP13,SERBP1,DBN1,MSI2,RFC4,RFC3,RDH10,TFPI,BRCA1,PTK2,COTL1,MCM2,ODC1,PDE3B,NUDT15,ARIH2,RAD54B,CHAF1A,DKK1,TAF9B,EXO1,IREB2,POLE2,SSU72,SH3RF1,H2AFX,SLC25A19,NCBP2,TBL1X |
| 1.663e-03 | -6.40 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | 195 | 40 | 17758 | 2279 |
ARHGAP26,SART1,MINK1,ID1,SPATA2L,PTPRA,ZFP36L1,NECAP1,BHLHE40,SAFB2,MFSD10,PABPC4,DDIT4,NAMPT,NDUFV1,SOCS1,COPS7B,TSPAN14,ATP6V0D1,CDC37,ZBTB17,LSM12,UPP1,WDR18,HSPA5,ATP6V0A1,MAPK1IP1L,MCL1,COTL1,HERPUD1,PAF1,DDX3X,NSD1,TPD52L2,EIF4ENIF1,ARL4A,CDK9,GLG1,SIL1,DHCR7 |
| 1.663e-03 | -6.40 | HALLMARK_ADIPOGENESIS | MSigDB lists | HALLMARK_ADIPOGENESIS | 195 | 40 | 17758 | 2279 |
NDUFA5,AK2,SUCLG1,LPCAT3,CHCHD10,REEP5,ETFB,DECR1,PTRF,TANK,ME1,HIBCH,CMPK1,COQ3,MGLL,SLC25A1,LAMA4,ACADS,RREB1,GPHN,PPARG,BAZ2A,ELOVL6,IDH3G,ANGPTL4,ECH1,UBC,PLIN2,CAT,RETSAT,GADD45A,ARL4A,ACOX1,COQ9,PEMT,HSPB8,RIOK3,SCARB1,GPAM,DHCR7 |
| 1.663e-03 | -6.40 | GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN | 195 | 40 | 17758 | 2279 |
SARS,MCM6,MCM10,CD226,SLC39A1,FDX1,DCTPP1,ASNS,SUV39H2,COPS3,MCM5,PAK1IP1,SHMT2,RAN,NDUFA6,TRIP13,HMGCR,MTHFD1,RFC4,SSFA2,PPAT,EIF3J,CDK4,ELOVL6,TPM4,VIM,MCM2,MAT2A,STOML2,SLC39A14,SLC7A1,ASCC3,EPRS,ALG5,RBBP8,H2AFX,SQLE,DPP4,EIF2S1,MED20 |
| 1.667e-03 | -6.40 | mitochondrial matrix | cellular component | GO:0005759 | 390 | 70 | 17570 | 2233 |
LYRM4,SUCLG1,RARS2,MRPL10,PDK4,FDX1,FLAD1,DECR1,SHC1,CBR4,SUCLG2,HIBCH,SSBP1,FXN,MTHFD2L,PPM1K,LONP1,TMLHE,MCEE,ACADS,NARS2,GARS,PDK1,MRRF,MCL1,MTHFD1L,CA5B,POLG2,DLST,ATP5D,PYCR1,TIMM44,GLS,TRMT5,DNAJA3,TXN2,UQCC2,DMGDH,BCKDK,AUH,LARS2,C10orf2,HSD17B10,FARS2,GFM2,ETFB,YARS2,NDUFS7,MRPS11,PMPCA,SHMT2,HARS2,PHYKPL,MRPL21,PCK2,COQ3,NT5M,DDX28,WARS2,PCCA,IDH3G,PDE2A,MMAA,LYRM7,MRPL36,ETFDH,TRAP1,D2HGDH,PDSS2,GCSH |
| 1.668e-03 | -6.40 | ATAD3B (ATPase family, AAA domain containing 3B) | protein interactions | 83858 | 34 | 12 | 16036 | 2270 |
DYRK1B,EPRS,EIF2S2,SHC1,SRP68,USP20,MLH1,USP11,FTSJ3,AGO3,UBC,NOP56 |
| 1.668e-03 | -6.40 | XPOT (exportin, tRNA) | protein interactions | 11260 | 34 | 12 | 16036 | 2270 |
USP7,RANBP2,CAMKK2,APEX1,MYC,SIRT7,RNF2,NFRKB,RAN,XPO7,NUP214,GCSH |
| 1.668e-03 | -6.40 | ITGB4 (integrin beta 4) | protein interactions | 3691 | 34 | 12 | 16036 | 2270 |
SMAD3,DST,COL17A1,SHC1,JUP,SREBF2,ARRDC3,ATXN1,VIM,PTK2,PRKCA,MET |
| 1.671e-03 | -6.39 | SANT | smart domains | SM00717 | 49 | 15 | 9131 | 1249 |
CHD7,DNAJC2,NCOR2,EP400,SMARCC1,GON4L,TRERF1,DNAJC1,NCOR1,DMTF1,SNAPC4,RERE,CRAMP1,MYB,TERF2 |
| 1.677e-03 | -6.39 | SRSF1 (serine/arginine-rich splicing factor 1) | protein interactions | 6426 | 161 | 37 | 16036 | 2270 |
SART1,CUL7,FN1,UTP14A,CLK1,PHGDH,UBR5,SUB1,SRSF2,ZNF326,TNPO3,SHMT2,RNF2,AHCYL1,SRRM2,CDK6,CDK12,HNRNPM,TOP1,SRPK2,PRPF19,SF3A1,SCAF11,SMARCAD1,WDR18,BRCA1,UBC,SYNCRIP,HNRNPR,TP53BP1,COPS5,HNRNPH3,SNAP23,LUC7L3,CUL2,PRPF4,IGBP1 |
| 1.684e-03 | -6.39 | PKMTs methylate histone lysines | REACTOME pathways | R-HSA-3214841 | 64 | 18 | 8202 | 1117 |
AEBP2,KMT2D,SETD1B,KMT2E,PRDM16,SETD2,EHMT1,ATF7IP,HIST1H4J,SETD7,KMT2C,DOT1L,NSD1,EHMT2,SUV39H2,HIST2H3D,KMT2A,SMYD3 |
| 1.684e-03 | -6.39 | GSE14000_TRANSLATED_RNA_VS_MRNA_DC_UP | MSigDB lists | GSE14000_TRANSLATED_RNA_VS_MRNA_DC_UP | 189 | 39 | 17758 | 2279 |
KCTD7,MCM6,PRDX6,C10orf2,ACTR3,OSBPL9,NAT10,NECAP1,CDC73,YARS2,GART,ACD,UCHL5,CBR4,ZNF326,DTNBP1,HIRIP3,POLR1B,NDUFA6,MCEE,RFC3,SMARCAD1,EIF3J,MED27,LDHA,BCS1L,PLEKHM3,ARID1A,FOXRED1,SAP30BP,TARS,DNAJA3,POLR3E,EIF2S1,RIOK1,EIF2B3,XRCC4,FAHD1,SMYD3 |
| 1.684e-03 | -6.39 | EGFR_UP.V1_DN | MSigDB lists | EGFR_UP.V1_DN | 189 | 39 | 17758 | 2279 |
EFNB2,DMXL2,NDUFA5,ID1,C16orf45,SMAD7,ZNF107,ID2,KIF5C,ATF7IP,RNF43,CSTA,SLC1A1,CHN1,PRKD3,FAM50A,CBR4,GPATCH1,LTN1,GREB1,PEG10,NRIP1,AGL,PRKACB,MYB,PTBP2,SSFA2,SIGMAR1,SATB2,CAV1,TMEM187,DDX60,IRS1,BAZ2B,ARL4A,DNAJC12,TAF12,BRCC3,TSPAN5 |
| 1.684e-03 | -6.39 | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | 189 | 39 | 17758 | 2279 |
FEM1C,CDC42EP2,FOXO1,B4GALT5,SPRYD7,ID2,ZFP36L1,FOSL2,HSPA1A,MYC,SLC38A2,RELB,CCDC40,ETF1,CLDND1,ERRFI1,NRIP1,ZMYM2,KDM6B,IFRD1,TRIM13,LIMA1,ANKRD33B,ZNF654,MARCKSL1,VIM,MCL1,ODC1,KLF6,HERPUD1,NCDN,HSPA1B,ZC3H12A,SKIL,HIF1A,ZNF81,CSRNP1,NFKBIB,TMCC1 |
| 1.684e-03 | -6.39 | GSE13493_DP_VS_CD8POS_THYMOCYTE_DN | MSigDB lists | GSE13493_DP_VS_CD8POS_THYMOCYTE_DN | 189 | 39 | 17758 | 2279 |
ZNF786,SARS,OXNAD1,BCKDK,PRPF31,TTC27,KLHL18,INPP1,DHX35,HDDC2,SLC30A7,ARHGAP18,CACNB2,POLR1B,ERI3,CCDC88C,PRMT3,RABEPK,ACSL5,DPF3,RFC4,PARP2,KCNMA1,TMEM126A,SLC35G1,SCFD2,ADSL,ENC1,HLA-DMA,RARS,TMEM237,POLE2,PMEPA1,TSEN2,POLR1C,PPIL3,PRKAR2A,FGFBP3,TMEM33 |
| 1.684e-03 | -6.39 | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN | 189 | 39 | 17758 | 2279 |
YDJC,IMMP2L,MCM6,DDX18,VPS45,VTI1A,PPP2R2A,JMJD6,SAFB2,SYNJ1,AARS,MRPS30,ANXA7,SREBF2,APLF,SUCLG2,GEMIN4,FBXO31,ERI3,PRMT5,LPCAT1,SF3A1,PMS1,MPP6,GARS,AP4B1,RNH1,YIPF3,NUP214,NAPEPLD,ANGPTL4,VAC14,INF2,MYBBP1A,METTL6,SLC4A7,TMEM219,COPS6,TSEN2 |
| 1.684e-03 | -6.39 | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | 189 | 39 | 17758 | 2279 |
CHST11,ZNF516,RCAN1,SLC29A1,MLH1,NUP43,CUTC,FAM192A,FARSA,KIAA1958,DHX33,NUP133,MCM5,CCDC40,HIBCH,LONP1,SLC25A1,MBTPS2,FADS1,TIMM8B,TRIM13,IDH3G,HSPA5,FZD3,METTL15,MTHFD1L,ZDHHC14,ZNF251,TPK1,EXOC6,YIF1A,CDC16,RBBP8,TRAP1,FDPS,CCDC146,HK2,GCSH,PTPN14 |
| 1.684e-03 | -6.39 | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | 189 | 39 | 17758 | 2279 |
RAB11FIP4,ITPRIP,XPC,PPARGC1B,OSBPL9,RNF24,ZFP36L1,DPM3,RPS6KA5,PITPNM1,TMEM150C,HVCN1,ANXA7,ARHGAP18,HIRIP3,TIMELESS,PABPC1,PRKACB,PTPRK,MYB,GATAD2B,KDM5B,FGF2,ANKMY2,TSN,PTPN12,MEF2D,CRYBG3,ZRANB3,BTBD11,EXOC6,ZFP62,GPN1,NCOR1,NRP1,TBCK,BRD9,DMTF1,METTL2B |
| 1.697e-03 | -6.38 | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | 380 | 69 | 17758 | 2279 |
ZNF254,CUL4A,PRDX6,UROD,ENAH,PIBF1,ATG3,IPP,CHD2,NT5C,MET,ZMYM2,OGG1,SRPK2,LAMA4,FLNC,DPF3,ARHGAP17,FBXW4,RBCK1,SSFA2,MCL1,SLC35F2,COTL1,MARCH6,LAMA2,AKAP13,SGK2,SAP30BP,DCBLD2,IKZF4,SMARCC1,LUC7L3,PER1,CLU,TBXA2R,TSPAN5,TTN,ZHX3,TCF3,DBF4,H2AFJ,KCNJ14,NAMPT,PI4KB,NEBL,GTF2H1,PTGS1,ANP32B,POLR1B,CD44,FADS1,GTF2H3,PXN,LAMC1,MYO10,PSMC3IP,ZMYM5,IL6R,ARID1A,OASL,EIF5B,VCAN,ZNF160,ZNF32,RBPJ,PRKAR2A,RABEP1,HS2ST1 |
| 1.698e-03 | -6.38 | - | gene3d domains | 1.10.1900.10 | 5 | 4 | 9988 | 1398 |
PABPC1L,UBR5,PABPC1,PABPC4 |
| 1.710e-03 | -6.37 | TGFBR1 (transforming growth factor, beta receptor 1) | protein interactions | 7046 | 189 | 42 | 16036 | 2270 |
GNB3,STX8,BTBD2,TTC27,WDR13,UBXN1,SMAD7,PPP2R2A,TGFB2,CSNK1A1,TGFBR2,SKI,CHN1,TTC1,FKBP1A,NEK6,IKBKB,SOCS6,RAN,PEG10,CD44,CDK6,TTPAL,WDR61,SKAP2,CDK4,CAV1,ENC1,SMAD3,SKIL,OXSR1,TRAP1,PRPF4,PPP3CC,CLU,RNF130,WDR33,USP11,TPM1,NRP1,ZAK,USP15 |
| 1.717e-03 | -6.37 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP | 177 | 37 | 17758 | 2279 |
EPM2AIP1,CELSR1,PAFAH1B1,ST6GAL1,TNXB,KIF5C,NECAP1,TRIM22,GDPD5,TGFBR2,FOXO3,MBNL1,PIP4K2A,AHCYL2,LPIN1,ABCA7,DOPEY1,CD96,ABCA5,CD44,ADARB1,SIK3,FBXW4,IL11RA,JMJD1C,EIF4A2,MCL1,R3HDM2,KLF6,TPK1,ANXA1,KIF16B,LSM14A,HERC1,SGSM2,TPM1,N4BP2L2 |
| 1.725e-03 | -6.36 | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_UP | 147 | 32 | 17758 | 2279 |
TNIK,PTCD2,TTN,CYLD,NPAS2,URB2,MKS1,RNASEH2B,RPS6KA5,BZW2,URB1,TRIM66,IGF2BP3,TMEM161A,PMAIP1,LPIN2,UBAP2L,SUCLG2,SYNJ2,SNX29,PTPRK,WDR61,COL5A2,NPM3,ATF7IP2,CAMSAP2,APTX,SOX4,TTC28,CCDC28B,DNAJA3,SLC16A10 |
| 1.727e-03 | -6.36 | TAF1D (TATA box binding protein associated factor 1D) | protein interactions | 79101 | 43 | 14 | 16036 | 2270 |
UBTF,POLB,RRN3,DDAH2,MYBBP1A,ITFG1,POLR1A,CENPB,CSNK2A1,POLR1B,POLR1C,POLR1E,TMSB4X,SMARCB1 |
| 1.727e-03 | -6.36 | WDR61 (WD repeat domain 61) | protein interactions | 80349 | 43 | 14 | 16036 | 2270 |
PAF1,RNF40,DDX3X,RARS,DNAJC2,CUL4A,UCHL5,COPS5,HK2,CTR9,MLH1,KMT2A,UBE2K,CDC73 |
| 1.728e-03 | -6.36 | BENPORATH_NOS_TARGETS | MSigDB lists | BENPORATH_NOS_TARGETS | 171 | 36 | 17758 | 2279 |
USP7,JUP,FOXO1,H2AFJ,RNF24,ZFP36L1,ZIC2,TRIM22,UBR5,ARID1B,PTPN2,NEBL,VPS52,ANO8,HN1,LAMA4,WDR36,KIAA1143,FGF2,SMARCAD1,TLE3,KIF15,CPT1A,FGFR1,RAD54B,MLLT10,DKK1,POLR3G,SKIL,TCF7L1,SPAG9,SET,LARGE,TAF12,TNRC6A,KAT6A |
| 1.729e-03 | -6.36 | PID_HES_HEY_PATHWAY | MSigDB lists | PID_HES_HEY_PATHWAY | 47 | 14 | 17758 | 2279 |
NCOR2,CAMK2D,RBBP8,ID1,GATA6,HIF1A,SPEN,TCF3,HES6,RCAN1,RBPJ,NCOR1,KDM1A,MYB |
| 1.735e-03 | -6.36 | V$E2F_Q2 | MSigDB lists | V$E2F_Q2 | 165 | 35 | 17758 | 2279 |
SNX27,UROD,NSUN6,ST7L,RLF,PIP4K2A,CDC73,POGZ,PABPC4,SUV39H2,WAC,RNF2,CMPK1,PRKACB,SERBP1,CSGALNACT2,PRDM16,POU2F1,SCMH1,PUSL1,NCDN,YTHDF2,HTR7,DDX50,HNRNPR,ZBTB8OS,SDCCAG8,PPP1R12B,ZNF32,ARHGAP12,EIF2B3,BMI1,KIF1B,ATXN7L2,LRRC41 |
| 1.753e-03 | -6.35 | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 642 | 108 | 17758 | 2279 |
PHF3,RSL1D1,ENAH,TUBB6,HMOX2,UBTD2,FLNB,PCDH7,ZNF827,ESAM,NEK6,YLPM1,DHX33,INTS12,AVEN,KIAA1549,TMLHE,PRPF19,STAMBP,PTPRM,TFPI,SLC35F2,C10orf76,SOX4,TBC1D16,ARL5B,FKBP3,SLC50A1,HSD3B7,TPK1,PEX1,BSN,GEMIN5,SUFU,SMARCC1,SH3RF1,PEMT,KLF4,RLTPR,CEBPZ,MBTD1,HIC2,DISP1,SPOCK2,MTCH1,MEF2C,SLC12A7,HMGA2,CTU2,CADM4,TNIK,DNAJC2,PGPEP1,TTC27,FAM189B,RHOBTB1,VTA1,SESTD1,MAP1S,IGF2BP2,QSER1,KCNJ14,SLC1A1,ANXA10,SFR1,PRKCH,FKBP1A,PRKCE,ABL1,SH2B3,NAV1,SEC24C,ZNF326,PRICKLE2,IGF2BP1,ACTR3B,TERF2,NIPSNAP1,ZNF629,MSI2,FAM71E1,ELOVL6,ABCF2,BMS1,ARHGAP32,RABAC1,GPNMB,PEAK1,NOP58,TMEM175,CHCHD6,POLR3G,DAGLA,FBXO21,EPRS,MYBBP1A,CDK9,RNF138,CCDC85B,CSRNP1,GPN1,UMPS,ITGB4,NR2F2,FNBP1L,IGBP1,MIPOL1,IPO4 |
| 1.755e-03 | -6.35 | YGCGYRCGC_UNKNOWN | MSigDB lists | YGCGYRCGC_UNKNOWN | 309 | 58 | 17758 | 2279 |
IMMP2L,ESCO1,PCNT,NPAS2,PPARGC1B,UROD,DLGAP4,SLC25A12,LPCAT3,ZIC2,IKBKAP,RPS6KA5,SEMA6A,KDM1A,BRE,MLX,KDM2A,ATP5G2,DCTN4,WAC,ANAPC10,PDS5B,TIMELESS,GEMIN4,SERBP1,SPTAN1,FAM98A,XPO5,ATG12,POU2F1,EIF2A,LENG8,EXOG,ZDHHC14,SLC9A5,SERP1,RAB10,MLLT10,UBTF,MTHFD2,SYNCRIP,PALB2,GTF2A1,ZBTB8OS,HNRNPR,FAM206A,HIC2,SLC25A11,PPP3CC,NR2F2,MAGI1,MMP16,PRKAR2A,KDM4C,SGSM3,MAPT,DDIT3,HS2ST1 |
| 1.764e-03 | -6.34 | in utero embryonic development | biological process | GO:0001701 | 350 | 65 | 16441 | 2138 |
CUL4A,PCNT,BIRC6,WDR74,MYH9,NLE1,SLC39A1,KDM1A,RPGRIP1L,SBDS,SMARCB1,CHD7,RRN3,DNAJB6,XRCC2,ANKRD11,PRPF19,DSC3,KMT2D,BRD4,COL4A3BP,PITPNB,FLVCR1,POLG2,TCTN1,FGFR1,SMAD3,SKIL,EPN2,BRCA2,RBBP8,GATA6,MKL2,RAD51B,RUNX1,CCNB1IP1,SEC24D,MAPK8IP3,ZFP36L1,RNASEH2B,MBNL1,ELL,EIF2S2,COPS3,CTR9,YBX3,AMOT,SOX6,MYB,TERF2,MSX1,RDH10,SETD2,LIG4,PRDM1,FOXC1,MFN2,RPA1,PALB2,KIDINS220,HIF1A,TBX3,RBPJ,NR2F2,STK4 |
| 1.769e-03 | -6.34 | CACTGTG,MIR-128A,MIR-128B | MSigDB lists | CACTGTG,MIR-128A,MIR-128B | 322 | 60 | 17758 | 2279 |
AK2,KIAA0232,NHS,MAPK8IP3,LETMD1,CLSTN2,MED13L,ENAH,ZFP36L1,RPS6KA5,UBR5,ARID1B,PDE3A,PAIP2,ZNF827,EIF2S2,HAS3,UBR1,SOCS6,ACOT11,TNPO3,GLTP,CPSF3L,NAV3,FAM184A,FADS1,FOXN3,AGPAT4,ELOVL6,RAP1B,RSBN1,FAM126B,ARID1A,MEGF11,ARRDC4,EVI5,SYT1,PHF6,RERE,IRS1,CDH24,ARHGAP21,BAZ2B,LMBR1L,IKZF4,SH3RF1,KLF4,SET,TAF4,ORC5,PTPN4,ARHGAP12,CNOT6,DIRAS1,RPS6KB1,GPAM,BMI1,MIPOL1,C18orf25,SMG1 |
| 1.772e-03 | -6.34 | Signaling Pathways in Glioblastoma | WikiPathways | WP2261 | 80 | 20 | 4455 | 564 |
BRAF,MAP2K5,NRAS,FOXO1,NF1,CDK4,BRCA1,PRKCA,PIK3CB,FOXO3,MAP2K3,FGFR1,PRKCH,IRS1,BRCA2,ATM,MET,ERRFI1,MAP2K4,CDK6 |
| 1.784e-03 | -6.33 | nucleus organization | biological process | GO:0006997 | 128 | 29 | 16441 | 2138 |
CHMP2A,PAFAH1B1,ASUN,PPP2R2A,TOR1AIP2,NUP43,PRKCA,NUP160,NUP214,CHD5,LPIN1,POM121,PES1,RRN3,RANBP2,ATXN7,NEK6,USPL1,NUP133,LEMD3,HIPK2,BANF1,TBPL1,POLR1B,NOLC1,SEH1L,CHMP4C,SRPK2,TMEM33 |
| 1.806e-03 | -6.32 | LDOC1 (leucine zipper, down-regulated in cancer 1) | protein interactions | 23641 | 62 | 18 | 16036 | 2270 |
FAM208B,AEBP2,ATF4,UTP14A,PRPF31,DPF2,PSMA1,INPP1,PSMF1,CTNNBL1,IKZF5,SETD5,MYC,AP1M1,CCDC85B,PEG10,NRIP1,ZBTB24 |
| 1.806e-03 | -6.32 | FAM96B (family with sequence similarity 96, member B) | protein interactions | 51647 | 62 | 18 | 16036 | 2270 |
CTU2,FMNL3,PRIM2,PPAT,TYW1,ELP3,SON,MAK16,EDC3,FBXL5,IREB2,ELP2,ELP5,USPL1,DNAJB6,CDKAL1,GGT7,FMNL2 |
| 1.806e-03 | -6.32 | RALY (RALY heterogeneous nuclear ribonucleoprotein) | protein interactions | 22913 | 62 | 18 | 16036 | 2270 |
CUL7,FN1,LIN28B,KHDRBS1,RANGAP1,MED16,PHF6,RPA1,RANBP2,SYNCRIP,HNRNPR,FMNL1,SHMT2,RNF2,CELF1,BMI1,PABPC1,HNRNPM |
| 1.809e-03 | -6.32 | organonitrogen compound biosynthetic process | biological process | GO:1901566 | 984 | 159 | 16441 | 2138 |
SRM,GGT1,EIF3C,RARS2,AARS2,MRPL10,CERS5,PLOD1,COX10,AARS,LPIN1,PABPC4,MRPS30,SRPRB,AMPD3,MMP7,RPS16,ATP5G2,PPCDC,HYAL1,ME1,FXN,YARS,CSGALNACT2,EIF4E3,GCNT2,HARS,UPP1,COL4A3BP,MTHFD1L,ODC1,ST3GAL5,MGST1,STOML2,PYCR1,DDX3X,GLS,HPRT1,EEFSEC,BDH2,SEPHS2,CARS,SARS,AK2,CHST11,LARS2,SSR4,PHGDH,YARS2,IGF2BP3,NAMPT,EIF2S2,ATIC,VAPB,ALDH18A1,MRPL21,PRPS1,PABPC1,PPA1,NT5E,MTHFD1,GTF2H3,WARS2,PPAT,EIF4A2,ST6GALNAC3,EIF2A,IMPDH2,MTR,ABCF1,EPRS,MTHFD2,GSTO2,NME7,RPL28,VCAN,SRP68,SURF1,TBPL1,CDKAL1,UMPS,HMBS,CNDP2,GGT7,SRP14,HS2ST1,LPCAT2,CEMIP,RPS29,UROD,ST3GAL6,DENR,FLAD1,CAD,FARSA,ASNS,PYCRL,LPIN2,MRPS27,GSTA4,ETF1,CMPK1,MTHFD2L,TMEM14C,TMLHE,NARS2,GARS,NARS,MTIF2,EIF3J,CPOX,MRRF,ATP6V0A1,SLC35D1,MAT2A,EIF3H,WARS,TPK1,SNCA,ATP5D,ALAD,COPS5,PEMT,ABHD3,FTSJ1,LARGE,EIF2B3,B4GALT5,MRI1,AGO2,FARS2,APRT,VARS,CHCHD10,TGFB2,GFM2,MRPS11,GART,GATC,HAS3,SHMT2,SELT,HARS2,RPL22L1,RPS6KB2,GPHN,PSAT1,MRPS10,ADSL,MARS,GUF1,EIF5B,MMAA,TARS,MRPL36,RARS,GPC2,EIF2S1,ADK |
| 1.816e-03 | -6.31 | NOL6 (nucleolar protein 6 (RNA-associated)) | protein interactions | 65083 | 30 | 11 | 16036 | 2270 |
NAP1L5,MPHOSPH10,NOL10,DDX24,DDX18,SIRT7,RNF2,FBL,BMI1,NOP58,NOP56 |
| 1.816e-03 | -6.31 | CBX7 (chromobox homolog 7) | protein interactions | 23492 | 30 | 11 | 16036 | 2270 |
PHC2,PCGF3,SRBD1,SUV39H2,UCHL5,CSNK2A1,USP20,RNF2,BCOR,BMI1,RING1 |
| 1.822e-03 | -6.31 | HIV Infection | REACTOME pathways | R-HSA-162906 | 221 | 46 | 8202 | 1117 |
CHMP2A,TAF1,GTF2H2C,VTA1,AK6,NUP43,AP1B1,NUP160,PSMF1,POM121,ELL,NUP133,TAF3,BANF1,AP1M1,GTF2H1,RAN,SEH1L,GTF2H3,VPS37A,RNMT,TCEB3,LIG4,PSMA1,PACS1,RANGAP1,SUPT5H,NELFA,NUP214,POLR2A,UBC,TAF9B,TAF2,RANBP2,KPNA1,SUPT4H1,GTF2A1,CCNT1,CDK9,VPS37B,TAF4,NCBP2,TAF12,XRCC4,AP2S1,CHMP4C |
| 1.827e-03 | -6.31 | organophosphate biosynthetic process | biological process | GO:0090407 | 435 | 78 | 16441 | 2138 |
PIGM,MVK,SUCLG1,LPCAT2,PIGH,LPCAT3,LCLAT1,SYNJ1,LPIN1,CAD,FLAD1,AMPD3,IDI1,ATP5G2,LPIN2,PPCDC,ME1,CMPK1,MGLL,MTHFD2L,GARS,UPP1,GPCPD1,ATP6V0A1,PITPNB,ATP5D,STOML2,TPK1,TAMM41,HPRT1,DCXR,G6PD,PEMT,ABHD3,XYLB,SERINC5,PIGN,AK2,GPAT3,PIK3R4,CHCHD10,PLA2G12A,APRT,DPM3,PIP4K2A,NAMPT,GART,PI4KB,ATIC,PIGG,SYNJ2,CPNE7,PNPLA3,LPCAT1,PRPS1,NT5E,MTHFD1,FADS1,GPHN,FGF2,PPAT,AGPAT4,ADSL,IMPDH2,PIK3CB,VAC14,ALG5,SERINC1,NME7,SRD5A3,FDPS,SURF1,TBPL1,ATM,UMPS,GPAM,MTMR1,ADK |
| 1.828e-03 | -6.30 | - | gene3d domains | 3.40.50.800 | 11 | 6 | 9988 | 1398 |
HARS2,EPRS,GARS,POLG2,HARS,TARS |
| 1.834e-03 | -6.30 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | 101 | 24 | 17758 | 2279 |
SEPHS2,CAMKK2,IFNGR2,SIGMAR1,PPAT,ELOVL6,H2AFJ,CACNA1H,MYH9,SETD7,USP46,MAT2A,FRRS1,EXO1,MGAT2,SKIL,SRSF2,GART,ACP1,BMP4,LPCAT1,ZMAT3,TNRC6A,PRPF19 |
| 1.842e-03 | -6.30 | upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma | 1540 | 235 | 17775 | 2278 |
MYCBP2,THOC5,PHF3,FEM1C,UBN1,NF1,ATRX,POLR1A,FANCD2,TRPM6,TUBE1,BCOR,COX10,SYNJ1,SCAF8,SMARCB1,DST,PDZD2,SREBF2,ZFHX3,FAAH2,SLC39A7,ANKRD11,MYH3,RNF111,ZEB1,KDM5C,DSC3,NRAS,ANK2,VWCE,GDPD1,PLEKHM3,LAMA2,KMT2C,DENND4A,CRYBG3,BSN,YTHDF2,DDX3X,BRCA2,TRRAP,INSIG1,CTAGE5,VPS13D,CSMD3,DNAH2,RIOK1,GALNT10,TNFRSF10D,WDR66,RNF214,DCAF5,USP15,LPP,MEF2C,SEPHS2,HERC2,EP400,SARS,FN1,CELSR1,ANKRD17,ZHX3,LARS2,CLK1,SIRT7,PRSS3,PRAF2,PID1,RSF1,EVPL,TGFBR2,CHD5,RHBDD1,ENTPD5,SCAF1,SAMD11,PIGG,SYNJ2,PRMT5,N4BP2,SERBP1,CPSF3L,GATAD2B,SCAF11,LAMC1,RREB1,PPAT,ELP3,JMJD1C,RAP1GAP2,HAUS6,RYR2,ATAT1,LIG4,OBSCN,CORIN,EHBP1,SLC26A11,ZNF655,ISG15,DYNC1H1,PRPF40B,LRP1B,FAM135A,GTF2A1,VCAN,SPEN,ZZEF1,DNAH17,ZNF430,NCOR1,SRP14,PDE9A,MAP2K4,RTTN,DMXL2,SPRED2,SART1,RAB11FIP4,ASH1L,TRPM2,OLFM2,DDX18,ATP6V1A,URB2,PSTPIP2,GPR143,COBLL1,PBX1,MYH9,TMEM177,ZNF83,TNKS1BP1,PIBF1,PPP1R9A,GBF1,STAM,SBDS,ZSCAN5A,ZNF827,TMEM184A,ZSWIM7,ZFP37,CEP63,MSH4,MET,VCL,ZC3H3,LYST,TMEM200A,SEC24A,PMS1,KMT2D,SLCO6A1,METTL2A,ATXN1,PCNXL2,VIM,ATP8B2,DSP,ERC1,MAT2A,FGFR1,DHX57,TMEM186,WARS,RAD54B,RANBP2,IQCH,HYAL3,HIPK2,WDR7,RPS6KB1,TMEM101,RNF130,HEATR1,NOLC1,LAMA5,MID1,METTL2B,MAPT,TRIM36,LRCH1,NCOR2,BRAF,SUPT6H,B4GALT5,TRAK1,PDE4B,C1orf226,CLSTN2,PPHLN1,KIF5C,FOXP1,FOXO3,POM121,ABL1,SACS,GATC,NISCH,LTN1,ARHGAP1,DYNC2H1,PXN,FOXN3,ZC4H2,FERMT2,FAM126B,MEN1,LENG8,ZNF407,EIF5B,PDE3B,NAALADL2,TMEM175,UBC,RERE,CTIF,ZNF221,NSD1,SRCAP,ZNF155,IREB2,STX1A,TBX3,ORC5,FNTB,DNAJC12,MYOM2,TAF12,NDUFS5,SORCS2,MMP16 |
| 1.849e-03 | -6.29 | RSRC1 (arginine/serine-rich coiled-coil 1) | protein interactions | 51319 | 18 | 8 | 16036 | 2270 |
PAXBP1,UTP14A,TFIP11,CSNK2A1,JMJD6,BMI1,ACTR3B,SRPK2 |
| 1.849e-03 | -6.29 | desmosome | cellular component | GO:0030057 | 24 | 9 | 17570 | 2233 |
DSC3,DSC2,JUP,DSG2,PNN,EVPL,DSP,VCL,PERP |
| 1.849e-03 | -6.29 | BAF-type complex | cellular component | GO:0090544 | 24 | 9 | 17570 | 2233 |
DPF3,SMARCC1,ARID2,DPF2,SMARCD3,SMARCA4,ARID1A,ARID1B,SMARCB1 |
| 1.850e-03 | -6.29 | DSP (desmoplakin) | protein interactions | 1832 | 67 | 19 | 16036 | 2270 |
INSIG2,COL17A1,CUL7,AK2,JUP,SIRT6,SIRT7,PPP2R2A,VIM,EVPL,PRKCA,CSTA,DSP,RPA1,PRKCE,UCHL5,COPS5,CUL2,CASP10 |
| 1.850e-03 | -6.29 | SRP14 (signal recognition particle 14kDa) | protein interactions | 6727 | 67 | 19 | 16036 | 2270 |
SNU13,NIFK,FN1,TRA2A,DRICH1,DKC1,PHF6,NOP56,DDX56,P3H1,SRP68,COPS3,COPS5,ASB3,NOLC1,BMI1,PDLIM5,SRRM2,PRPF19 |
| 1.850e-03 | -6.29 | C14orf166 (chromosome 14 open reading frame 166) | protein interactions | 51637 | 67 | 19 | 16036 | 2270 |
FAM98A,RFC4,FN1,TCF3,PSMG1,ABCF1,FKBP3,RPA1,WARS,IGF2BP3,AHNAK,SYNCRIP,COPS5,CUL2,FUS,YBX3,EIF2B3,BMI1,ACTR3B |
| 1.857e-03 | -6.29 | JmjN | smart domains | SM00545 | 8 | 5 | 9131 | 1249 |
KDM5C,KDM5B,KDM4B,KDM5A,KDM4C |
| 1.863e-03 | -6.29 | GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN | 190 | 39 | 17758 | 2279 |
TCF12,IFT57,MCM6,RWDD1,RCHY1,KIF5C,ZFP36L1,CCDC47,HMOX2,RIOK2,CHN1,CD96,EIF2S2,COPS4,GTF2H1,RDX,CMPK1,NOC3L,PNMA1,KDM3B,PMS1,SKIV2L2,CPOX,TPM4,ADSL,TMEM123,GALK2,IL6R,RDH11,MGAT2,TMCO1,TPD52L2,INTS5,ARL6IP5,TBPL1,ZCCHC6,PEX13,TPM1,N4BP2L2 |
| 1.863e-03 | -6.29 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | 190 | 39 | 17758 | 2279 |
CDCP1,ABCA3,MCM10,MYNN,GYG1,ELL,ANXA7,PSMG4,NOP16,RELB,PCOLCE2,NOC3L,FBL,CCDC88C,PPA1,CASP10,C12orf4,PCSK6,ACSL5,ARNTL2,ABCC4,ZNF512B,DHX34,HSH2D,C1orf174,HERPUD1,WARS,SLC7A1,RARS,ATXN7,DDX50,CUL2,PQBP1,XPNPEP1,CASS4,TRAF3,HEATR1,PSAP,PUS1 |
| 1.872e-03 | -6.28 | IK (IK cytokine, down-regulator of HLA II) | protein interactions | 3550 | 72 | 20 | 16036 | 2270 |
CUL7,TRA2A,SIRT7,WDR18,FRA10AC1,SUPT5H,PHGDH,SAFB2,KDM1A,RANBP2,SRCAP,TOE1,MYBBP1A,CTNNBL1,CHD3,ZNF326,RNF2,NOLC1,BMI1,TOP1 |
| 1.872e-03 | -6.28 | TAF10 (TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa) | protein interactions | 6881 | 72 | 20 | 16036 | 2270 |
MCM6,PRPF31,TAF1,SKIV2L2,SMARCA4,SUPT20H,SETD7,SNAPC4,POLR2A,TAF9B,TADA3,TAF2,ATXN7,TRRAP,SMARCC1,TAF3,MYC,TAF4,TAF12,SPTAN1 |
| 1.874e-03 | -6.28 | CDC73 (cell division cycle 73) | protein interactions | 79577 | 77 | 21 | 16036 | 2270 |
WDR61,TFCP2,ITFG1,MYH9,WWC1,KCNH2,KMT2C,TCF7L2,POLR2A,RNF40,PAF1,RANBP2,DDAH2,KIDINS220,CDK9,VPS37B,RRAGA,CTR9,CPSF3,KMT2A,SRRM2 |
| 1.884e-03 | -6.27 | LUC7L2 (LUC7-like 2 pre-mRNA splicing factor) | protein interactions | 51631 | 162 | 37 | 16036 | 2270 |
CARS,CCDC53,ATRX,CSNK2A1,JMJD6,ATF7IP,CEP126,PABPC4,NEDD4,NOP56,EXOC1,SNW1,SHMT2,RNF2,PABPC1,CLK2,SRPK2,SF3A1,CDC37,SCAF11,PEA15,FAM98A,SSFA2,CDK4,TRA2A,ZC3H18,PNN,NAP1L5,SYNCRIP,CLASRP,NSF,CHD3,HNRNPR,COPS5,LUC7L3,SVIL,ZRANB2 |
| 1.886e-03 | -6.27 | GSE14308_TH17_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_TH17_VS_NATURAL_TREG_DN | 184 | 38 | 17758 | 2279 |
MYCBP2,ESCO1,RAB11FIP4,OSBPL9,PPP2R2A,HES6,RCAN1,PABPC1L,PHGDH,ABHD6,PELP1,PITPNM1,PAG1,CEP164,NUP133,SCAF1,RELB,GLTP,TTC3,FBXO31,FMNL3,CHD9,RBCK1,RAP1GAP2,ZNF512B,SCMH1,ZSCAN2,CA5B,WARS,FBXL5,TOM1L2,LUC7L3,ZZEF1,DPEP1,DHCR7,MUTYH,ZNF598,ZBTB24 |
| 1.896e-03 | -6.27 | macromolecular complex assembly | biological process | GO:0065003 | 1279 | 201 | 16441 | 2138 |
IMMP2L,EIF3C,UBN1,ATRX,AARS2,TRPM6,SBF2,SIRT2,COA1,SEC16A,COX10,SYNJ1,BIRC2,CUTC,EDC3,SKI,NEK6,S100A10,CNIH3,ZNHIT6,XRCC2,WIZ,ME1,LONP1,SRPK2,SF3A1,ACADS,SKAP2,BAZ2A,PSMG1,HIST1H2BL,CAV1,MCM2,FOXRED1,CLNS1A,MGST1,CHAF1A,STOML2,DDX3X,PAF1,GEMIN5,GLS,SKIL,HPRT1,AHNAK,LSM14A,LUC7L3,TNFRSF1A,RAD51B,FIS1,CLU,MAGI1,UQCC2,NOCT,TTN,FN1,PRPF31,SEC24D,TAF1,HSD17B10,RSF1,PRPF39,DNAH1,SLC1A1,NDUFS7,ABCA7,FKBP1A,HR,MBD2,ATXN2,MED24,ANP32B,GEMIN4,CCDC88C,PRMT5,PRF1,CAV2,POLR1E,HMGCR,SCAF11,DDX28,RANBP6,TRAPPC9,LAMC1,PPAT,TSPYL4,HAUS6,BCS1L,EIF2A,SNAP25,IMPDH2,TRAPPC6B,SYT1,CPT1A,ANGPTL4,NAP1L5,CAT,SEC31A,DYNC1H1,EPRS,TSR1,BICD1,SPAG9,NSF,SNAP23,SURF1,KIAA0196,NCOR1,NAPA,SMYD3,PDSS2,AGO3,VMA21,KCTD7,CHMP2A,SART1,CYLD,SLC2A1,C1QTNF7,COBLL1,RIPK1,PIBF1,SBDS,DENR,BLOC1S2,NUBPL,DECR1,KCTD11,PPID,CBR4,CCDC40,CEP63,TMEM120B,KMT2A,PRPF19,SEC24A,EVL,MPP6,PTBP2,EIF3J,C1QTNF1,PREX1,ARHGEF10,DLG4,ATP6V0A1,EIF3H,TAF2,ARMC4,HLA-DMA,SMAD3,CAMK2D,ALAD,KPNA3,DCXR,H2AFX,MDN1,ANXA2,AP2S1,PARD3,TMEM33,HMGA2,NIFK,SHQ1,BRAF,HM13,C10orf2,AGO2,SF3A3,TRIM22,MLH1,NOL3,IKBKAP,MBNL1,POGZ,MRPS11,DCTPP1,PSMG4,SEC24C,ANXA5,HIST2H3D,SHMT2,CELF1,TTC17,PXN,SMARCAD1,KCNMA1,FERMT2,ADSL,BMS1,HIST1H4J,PTK2,UBE2K,CENPP,SET,NCBP2,NDUFAF5,NDUFS5,APAF1,UQCC1,IPO4,KAT6A |
| 1.904e-03 | -6.26 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 | 136 | 30 | 17758 | 2279 |
DNAJC2,DDX41,TUBA1A,APEX1,NARS,WDR74,CDK4,MRPS10,SMARCA4,VARS,TUBB6,ODC1,DCTPP1,CAD,PES1,RARS,MYBBP1A,SYNCRIP,TANK,BANF1,SLC39A7,RAN,SERPINH1,FBL,VCL,TMEM14C,PPA1,HTRA2,CARM1,IPO4 |
| 1.905e-03 | -6.26 | PRDX3 (peroxiredoxin 3) | protein interactions | 10935 | 48 | 15 | 16036 | 2270 |
CUL7,NEK6,FN1,MAP3K13,UCHL5,SPEN,COPS5,CUL2,IKBKB,TNFRSF1A,H2AFX,OPA1,RPS6KC1,BIRC2,TERF2 |
| 1.908e-03 | -6.26 | angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | angioimmunoblastic_T_cell_lymphoma | 272 | 52 | 17775 | 2278 |
BRAF,FOXO1,OLFM2,ARID2,TAF1,TTC27,NF1,TRPM6,SMARCA4,ARID1B,ABCA7,SMARCB1,ABL1,DST,SH2B3,ZNF608,SRSF2,SOCS1,ZFHX3,MYC,PDS5B,TTC3,CHD2,KMT2A,NRAS,KMT2D,BRD4,SETD2,RAP1GAP2,PHACTR2,LAMA2,ARID1A,PRDM1,KMT2C,NUP214,TTC28,PHF6,DLEU1,ZNF708,DDX3X,G6PD,BCAS3,ATM,TRAF3,RUNX1,HEATR1,RFXAP,ZNF532,KDM4C,PARD3,MEF2C,LRRC41 |
| 1.912e-03 | -6.26 | GCM_RBM8A | MSigDB lists | GCM_RBM8A | 79 | 20 | 17758 | 2279 |
ZNF292,FAM172A,BAZ2A,FOXO3,POGZ,TAF9B,APBB3,UBE3A,SPAG9,KIDINS220,NUP133,SETD5,CLEC16A,DCTN4,GSTA4,ASB3,RAN,CELF1,CEP170,PKNOX1 |
| 1.914e-03 | -6.26 | mismatch repair | biological process | GO:0006298 | 28 | 10 | 16441 | 2138 |
ABL1,EXO1,PMS1,XPC,SETD2,MSH3,MLH1,MSH4,MUTYH,RPA1 |
| 1.914e-03 | -6.26 | double-strand break repair via synthesis-dependent strand annealing | biological process | GO:0045003 | 28 | 10 | 16441 | 2138 |
EXO1,RBBP8,BRCA2,PALB2,XRCC2,TOP3A,RAD51B,ATM,BRCA1,RMI1 |
| 1.914e-03 | -6.26 | mRNA polyadenylation | biological process | GO:0006378 | 28 | 10 | 16441 | 2138 |
PAF1,SSU72,PABPC1L,CPSF3,WDR33,AHCYL1,SYMPK,PABPC1,CDC73,ZC3H3 |
| 1.916e-03 | -6.26 | AAAGGGA,MIR-204,MIR-211 | MSigDB lists | AAAGGGA,MIR-204,MIR-211 | 215 | 43 | 17758 | 2279 |
SLC37A3,TCF12,HMGA2,PRPF38B,CELSR3,SEC24D,KHDRBS1,SPRYD7,MED13L,PID1,FAM122B,MON2,TGFBR2,RPS6KA5,CHD5,MBNL1,ANKRD13A,KDM2A,SHC1,TRIAP1,BUD31,SOCS6,NBEA,AUP1,MAML3,MALL,ZCCHC14,GPM6A,BRD4,MYO10,BAZ2A,ELOVL6,SATB2,SOX4,RAB10,RERE,SPOP,TCF7L1,HIC2,RPS6KC1,DMTF1,DCAF5,HS2ST1 |
| 1.921e-03 | -6.26 | SNRNP70 (small nuclear ribonucleoprotein, U1 70kDa subunit) | protein interactions | 6625 | 124 | 30 | 16036 | 2270 |
SCAF11,CUL7,CUL4A,FN1,TFIP11,SIRT7,HSPA5,TPM4,SF3A3,CSNK2A1,SMAD3,SKIL,SRSF2,SYNCRIP,HNRNPR,MYC,COPS5,CUL2,RNF2,ZRANB2,CEP63,COPS6,PRMT5,TXN2,TERF2,TOP1,CLK2,MTHFD1,SRPK2,PRPF19 |
| 1.922e-03 | -6.25 | POLH (polymerase (DNA directed), eta) | protein interactions | 5429 | 26 | 10 | 16036 | 2270 |
USP7,BRCA2,PALB2,RAD18,MYC,FANCD2,RCHY1,MLH1,BRCA1,UBC |
| 1.924e-03 | -6.25 | MORF_TPR | MSigDB lists | MORF_TPR | 142 | 31 | 17758 | 2279 |
KDM3B,TTLL5,TSTA3,ATG9A,XPC,ATRX,PRKCSH,FAM189B,SFSWAP,KIAA0586,RABAC1,TTI1,DENND4A,PARN,RING1,MFN2,TERF2IP,PWP1,TAF2,SEC31A,CHD3,TBPL1,CTAGE5,SLC25A11,PRPF4,KDM5C,NFRKB,IGBP1,XPO6,MPST,BAG1 |
| 1.924e-03 | -6.25 | IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR | 142 | 31 | 17758 | 2279 |
YDJC,COMMD10,ZNF706,PTCD2,NOSTRIN,THOC5,APEX1,KLHL23,SFXN4,PCCA,VPS45,HES6,ISG20L2,MFSD10,TMEM186,TAMM41,PES1,ZNF266,DHX37,ELP2,NEBL,CFDP1,POLR3E,CEBPZ,WDR73,C7orf50,SCARB1,KLHDC4,NOC3L,ZAK,RABEPK |
| 1.933e-03 | -6.25 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | 166 | 35 | 17758 | 2279 |
VIPR1,CARS,OXNAD1,SERINC5,FOXO1,C10orf2,TCF3,PRKCA,FOXP1,FLNB,KIAA1958,C6orf48,DDX31,COQ3,PLEKHG4,NT5E,PTPRK,FAM184A,ZNF629,C1orf228,APEX1,ERICH1,PDK1,SFXN4,RFX2,ZNF512B,OBSCN,ARHGAP32,USP20,SCARB1,TBXA2R,TSEN2,TNFRSF10D,PDE9A,SLC16A10 |
| 1.933e-03 | -6.25 | HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | REACTOME pathways | R-HSA-5693567 | 129 | 30 | 8202 | 1117 |
HERC2,RFC4,RFC3,POLK,SIRT6,TOP3A,BRCA1,HIST1H4J,HIST1H2BL,RMI1,UBC,RPA1,EXO1,ABL1,BRE,SLX4,BRCA2,RBBP8,PALB2,POLE2,TP53BP1,XRCC2,H2AFX,RAD51B,TIMELESS,ATM,ATRIP,EME1,BRCC3,SPIDR |
| 1.940e-03 | -6.25 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | 160 | 34 | 17758 | 2279 |
DMXL2,CHST11,MED13L,ID2,PRKCA,MRPS30,CD96,JAG1,TANK,CD44,ZMYM2,PRF1,CSGALNACT2,SAP30,SIK3,WDFY3,RAP1GAP2,PSMA1,KLF6,PDE3B,PLCB1,ZNF91,ST3GAL5,TCF7L2,HELZ,AGTPBP1,ARL4A,SPEN,KIAA0754,PER1,CFD,ABHD3,HIC2,ANKS1A |
| 1.942e-03 | -6.24 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | 542 | 93 | 17758 | 2279 |
SRM,SPRED2,ID1,PPARGC1B,FANCD2,TMEM109,SPATS2L,NUP43,NLE1,C1orf159,ARHGAP18,NUP133,UCHL5,XRCC2,LPIN2,ANKRD24,MAD1L1,HIRIP3,ZNRD1,TRIP13,CTC1,HN1,RFC4,FMNL3,RFC3,UPP1,AKAP12,WDHD1,GNL1,VIM,DKC1,MCM2,ODC1,SLC9A5,BATF3,GEMIN5,TAMM41,EXO1,BRCA2,ALAD,RAD18,H2AFX,ANXA2,EME1,ZC3H8,TPM1,NOLC1,ANKS1A,MEF2C,SHQ1,MCM10,MCM6,FN1,DBF4,NKD2,VARS,DCTPP1,SUV39H2,MCM5,TIMELESS,PABPC1,MYB,VOPP1,STAG1,PRIM2,TEAD1,POLA1,ELOVL6,PSMC3IP,HAUS6,KIAA0586,RANGAP1,PALLD,NOP58,POLR2A,SMPDL3B,CENPP,ZRANB3,ANXA1,RPA1,ATAD5,PDLIM1,POLE2,PALB2,VCAN,ZBTB12,TAF4,AEN,UMPS,C7orf50,ZAK,TESC,GPATCH4 |
| 1.943e-03 | -6.24 | HD/PDEase_dom | interpro domains | IPR003607 | 24 | 9 | 18293 | 2341 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,HDDC2,PDE8B |
| 1.947e-03 | -6.24 | BMS1 (BMS1 ribosome biogenesis factor) | protein interactions | 9790 | 11 | 6 | 16036 | 2270 |
CSNK2A1,SHMT2,RNF2,NIFK,SIRT7,USP42 |
| 1.947e-03 | -6.24 | RCVRN (recoverin) | protein interactions | 5957 | 11 | 6 | 16036 | 2270 |
SMAD3,CAV1,TGFBR2,GIT2,TOP1,PQBP1 |
| 1.950e-03 | -6.24 | METTL13 (methyltransferase like 13) | protein interactions | 51603 | 22 | 9 | 16036 | 2270 |
PTPN2,EFNB2,SYNCRIP,SMARCC1,SKIV2L2,TBC1D22A,MYC,ANKMY2,VPS52 |
| 1.950e-03 | -6.24 | LHX6 (LIM homeobox 6) | protein interactions | 26468 | 22 | 9 | 16036 | 2270 |
EHMT2,ARID3B,TLE3,ATG2B,SATB2,KDM5C,SSBP2,NUDT22,ZNF507 |
| 1.950e-03 | -6.24 | SPIN2B (spindlin family, member 2B) | protein interactions | 474343 | 22 | 9 | 16036 | 2270 |
MCM6,XPC,PARP2,ARHGAP39,WDHD1,XPNPEP1,FAM122B,MCM2,HIST2H2AB |
| 1.953e-03 | -6.24 | cell-substrate junction | cellular component | GO:0030055 | 399 | 71 | 17570 | 2233 |
ARHGAP26,ACTG1,ACTR3,RPS29,DDR2,MYH9,CD99L2,ENAH,GIT2,HSPA1A,FLNB,DST,RPS16,PPFIBP1,MMP14,VCL,FLNC,PHLDB2,EVL,LIMA1,HSPA5,AKAP12,VIM,CAV1,NUP214,RAB10,ARPC3,RHOU,AHNAK,MISP,ITGA2,DPP4,ADAM9,NFASC,NRP1,LPP,EFNB2,JUP,TRIP6,LAMTOR3,NHS,MCAM,ANXA5,RDX,CD44,PABPC1,PNMA1,CAV2,COL17A1,PXN,TPM4,ASAP3,PTPN12,ATAT1,LIG4,FERMT2,PTK2,PALLD,PEAK1,HSPA1B,ANXA1,CAT,PDLIM1,SRP68,FAT1,SNAP23,ADGRE5,CASS4,SVIL,ITGB4,PRKAR2A |
| 1.959e-03 | -6.24 | RNA methylation | biological process | GO:0001510 | 52 | 15 | 16441 | 2138 |
METTL16,METTL1,TRMT5,RNMT,TRMT13,TRMU,ALKBH8,METTL2A,FTSJ1,METTL15,TRMT2A,TRMT10A,FBL,METTL2B,FTSJ3 |
| 1.959e-03 | -6.24 | Nucleotide Metabolism | WikiPathways | WP404 | 20 | 8 | 4455 | 564 |
SRM,HPRT1,POLB,NME1-NME2,MTHFD2,POLA1,ADSL,PRPS1 |
| 1.960e-03 | -6.23 | SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | MSigDB lists | SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | 33 | 11 | 17758 | 2279 |
SPRED2,EGR1,SLC2A1,TUBB6,SYNJ2,BHLHE40,C12orf45,NOP58,MAK16,NOP56,HMGCR |
| 1.960e-03 | -6.23 | NUCLEAR_EXPORT | MSigDB lists | NUCLEAR_EXPORT | 33 | 11 | 17758 | 2279 |
NUP133,KHDRBS1,SMG7,ATXN1,NCBP2,UPF2,XPO7,NUP160,NUP214,XPO6,SMG1 |
| 1.966e-03 | -6.23 | MOOTHA_MITOCHONDRIA | MSigDB lists | MOOTHA_MITOCHONDRIA | 435 | 77 | 17758 | 2279 |
NDUFA5,SUCLG1,PTPRA,PDK4,NDUFB5,SLC25A21,COX10,RPAIN,FDX1,MRPS30,NDUFB3,CAD,FARSA,DECR1,ATP5G2,MRPS27,POLR3B,SSBP1,RAN,NDUFA6,FXN,SLC25A23,HTRA2,LONP1,MPST,ACADS,PDK1,MTIF2,CPOX,CA5B,POLG2,ATP5D,PYCR1,SNCA,TIMM44,TIMM17A,G6PD,SLC25A11,TXN2,MTCH1,BCKDK,AK2,LARS2,C10orf2,FARS2,SLC25A12,TIMM10,SLC1A1,ETFB,YARS2,MRPS11,SLC25A20,ANXA7,SHMT2,POLR1B,PCK2,NT5M,PPA1,TOMM34,LYPLA2,SLC25A1,MTHFD1,TIMM8B,DDX28,WARS2,PCCA,ABCF2,BCS1L,MRPS10,CYB5B,CPT1A,MFN2,CAT,ETFDH,MTHFD2,SURF1,APAF1 |
| 1.967e-03 | -6.23 | MYOG (myogenin (myogenic factor 4)) | protein interactions | 4656 | 39 | 13 | 16036 | 2270 |
TCF12,ID1,NF1,TCF3,PACRGL,ID2,SMARCA4,MLH1,IKBIP,PRMT5,SEPT5,CARM1,MEF2C |
| 1.981e-03 | -6.22 | parathyroid-carcinoma | COSMIC cancer mutations | parathyroid-carcinoma | 311 | 58 | 17775 | 2278 |
DMGDH,MPI,SLC5A5,XRRA1,NAT10,ARSJ,SEC16A,TNKS1BP1,CDC73,HNRNPA3,BIRC2,IGSF1,ECM1,CAMTA2,YLPM1,LRP2BP,ANKRD11,ZEB1,DDX31,CMPK1,ZCCHC7,TRMT12,SOX6,MICAL3,VPS13B,TMEM200A,SF3A1,HBG2,CAMKK2,NRAS,CRIM1,ELP3,ARID5B,HSPA5,OBSCN,TOR1AIP2,ZNF467,CA5B,MEN1,CHAF1A,KISS1R,CAT,ARMC4,BRCA2,TMEM237,SYNCRIP,TP53BP1,ZNF557,ZZEF1,G6PD,VPS37B,RIOK3,ALKBH1,VPS13D,RBM26,USP11,BRWD3,PTPN14 |
| 1.982e-03 | -6.22 | HISTONE_MODIFICATION | MSigDB lists | HISTONE_MODIFICATION | 24 | 9 | 17758 | 2279 |
KAT8,NSD1,SET,EHMT1,SIRT2,RPS6KA5,MAP3K12,CARM1,KAT6A |
| 1.985e-03 | -6.22 | HOSHIDA_LIVER_CANCER_SUBCLASS_S2 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S2 | 113 | 26 | 17758 | 2279 |
PHF3,CUL4A,DDX18,PPARG,TFIP11,EIF4A2,CSNK2A1,PNN,UBE2K,GBF1,PLXNB1,FLNB,CXADR,GNAI1,IDI1,HELZ,SMARCC1,SREBF2,ACP1,ATM,TTC3,FBL,CDK6,NT5E,CLK2,HMGCR |
| 1.989e-03 | -6.22 | - | gene3d domains | 3.30.40.10 | 438 | 83 | 9988 | 1398 |
MYCBP2,ASH1L,PHF3,ATRX,KMT2E,RCHY1,RNF24,RNF43,HLTF,EEA1,RING1,TRIM66,KDM2A,LONRF2,ZFYVE28,UBR1,ANAPC11,RNF111,INTS12,TTC3,RNF2,KDM5C,KMT2A,PRPF19,DPF3,PCGF3,TRIM13,KMT2D,RBCK1,BAZ2A,MARCH6,BRCA1,KMT2C,MLLT10,BSN,BAZ1A,RBSN,KDM4B,RAD18,SH3RF1,CHD3,NSMCE2,TRAF3,RNF130,BMI1,MID1,ZNF598,RNF214,TRIM36,DPF2,MEX3A,TRIM15,RSF1,TRIM22,CHD5,SPIRE1,RNF141,RSPRY1,RNF40,RNFT2,TAF3,PPIL2,LTN1,FBXL19,LRSAM1,CNOT4,MARCH9,SCAF11,KDM5B,ZFYVE1,WDFY3,USP49,KDM5A,MEX3B,TRIM37,ARIH2,NSD1,BAZ2B,RNF138,USP20,KDM4C,KAT6A,RNF114 |
| 1.994e-03 | -6.22 | organonitrogen compound metabolic process | biological process | GO:1901564 | 1764 | 269 | 16441 | 2138 |
GGT1,AARS2,MRPL10,NT5C3A,HMOX2,SLC6A8,AARS,LPIN1,PABPC4,MMP7,RPS16,ATP5G2,ME1,FXN,PPM1K,CSGALNACT2,GDAP1,EIF4E3,UPP1,ALDH1L2,STOML2,PYCR1,DDX3X,DDAH2,BDH2,XPNPEP1,SPOCK2,SPOCK3,CARS,LARS2,PLA2G12A,BTBD9,SSR4,NDUFS7,YARS2,IGF2BP3,EIF2S2,ENTPD5,ATIC,SLC16A9,MRPL21,LPCAT1,PRPS1,PABPC1,PPA1,HMGCR,GTF2H3,BDNF,AOC2,PCCA,EIF4A2,IDH3G,ST6GALNAC3,IMPDH2,CPT1A,MTR,ABCF1,CAT,EPRS,MTHFD2,GSTO2,NME7,RPL28,VCAN,SRP68,SURF1,DPEP1,UMPS,BPNT1,CNDP2,MACROD1,SRP14,CPT1C,HS2ST1,SDSL,PAFAH1B1,ATP6V1A,UROD,NDUFB5,OLA1,ST3GAL6,HSPA1A,PDE3A,NDUFB3,FLAD1,ASNS,PYCRL,LPIN2,MRPS27,GSTA4,NT5C,CMPK1,MTHFD2L,GARS,EIF3J,MTIF2,DLG4,ATP6V0A1,SLC35D1,NUDT15,MAT2A,PDE8B,SNCA,DCXR,G6PD,PEMT,LARGE,PAM,FTSJ1,SERINC5,B4GALT5,MRI1,FARS2,TGFB2,PSMF1,GATC,UNC13A,PHYKPL,HARS2,NT5M,RPL22L1,PFKFB4,PSAT1,LDHA,MRPS10,ADSL,PDE3B,GUF1,MMAA,FOXC1,MRPL36,RARS,COQ9,NDUFS5,PSAP,ADK,IMMP2L,SRM,EIF3C,SLC52A3,RARS2,CERS5,SLC25A21,PLOD1,COX10,AHCYL2,PCYOX1L,MRPS30,SRPRB,AMPD3,PPCDC,MYH3,HYAL1,NDUFA6,YARS,OGG1,MPST,ATF4,GCNT2,ITPA,HARS,COL4A3BP,MTHFD1L,DLST,ODC1,ST3GAL5,MGST1,GLS,MSRA,HPRT1,HLCS,EEFSEC,SEPHS2,AOC3,SARS,CHST11,AK2,PRSS3,HSD17B10,PCSK7,PHGDH,NAMPT,PDE10A,VAPB,GLTP,ALDH18A1,MTHFD1,NT5E,WARS2,PDE4A,PPAT,PSMA1,EIF2A,CORIN,PGD,TBPL1,HK2,CDKAL1,DTD1,HMBS,GGT7,PDE9A,NDUFA5,SLC5A5,LPCAT2,CEMIP,RPS29,LPCAT3,ARSJ,DENR,CAD,FARSA,HIBCH,ETF1,FHIT,AHCYL1,TMEM14C,HTRA2,TMLHE,MCEE,NARS2,NARS,CPOX,NLN,MRRF,EIF3H,TPK1,WARS,ATP5D,HYAL3,ALAD,COPS5,ABHD3,ATG7,EIF2B3,MUTYH,DMGDH,BCKDK,AUH,SULT1C2,AGO2,PDE4B,VARS,CHCHD10,APRT,GFM2,MRPS11,GART,NDUFV1,HAS3,SELT,SHMT2,CD44,RPS6KB2,PCSK6,GPHN,FGF2,SULT4A1,MARS,PDE2A,EIF5B,TARS,SMPDL3B,NEU1,HSPA1B,GPC2,SERINC1,EIF2S1,GCSH |
| 2.003e-03 | -6.21 | GRADE_COLON_CANCER_UP | MSigDB lists | GRADE_COLON_CANCER_UP | 817 | 133 | 17758 | 2279 |
THOC5,ACTG1,WDR74,PRKCSH,DDX19A,MFGE8,AARS2,ZNF107,CCNL2,COX10,PABPC4,AMPD3,S100A10,ANAPC10,AP1M1,SLC27A5,ZNF3,CARM1,SF3A1,ATF4,SKAP2,SHISA5,SOX4,ODC1,SLC9A5,SH3GL1,PEX1,ARPC3,EEFSEC,NSMCE1,SYNGR2,CRCP,ZNF598,PTPN14,MAPK8IP3,DLGAP4,GTF2IRD1,PDCD5,PITPNM1,SUB1,NAV1,INTS7,ATIC,MCM5,MYC,BANF1,GMDS,PPA1,TSTA3,IDH3G,PSMA1,RNH1,MEX3B,PRDM1,IMPDH2,PGD,EPRS,PALB2,SYNCRIP,EHMT2,TRAP1,FAT1,ZCCHC6,PFDN2,MACROD1,BRSK2,PPDPF,TRPM2,RPS29,ACTR3,OLA1,MYH9,LPCAT3,NOP56,PYCRL,IKBKB,ZDHHC6,SSBP1,PXK,MTHFD2L,PERP,GARS,GLTSCR2,TMEM123,PNN,UBR4,EIF3H,IQCH,HYAL3,SMARCC1,KPNA3,ADNP,DCXR,NSMCE2,G6PD,CBWD1,CENPBD1,NFRKB,TMEM101,ZNF18,PUS1,HM13,TCF3,SF3A3,MAP1S,LIAS,NDUFV1,SURF2,NOP16,UPF2,CPNE7,EXOSC4,FBL,LYPLA2,HNRNPM,HSD17B12,CLK2,MARCH9,APEX1,LSM12,C19orf43,ARHGAP39,LDHA,BMS1,PTK2,C8orf33,TARS,UBC,SET,BMP4,PSAP,PGAM5,C6orf223 |
| 2.014e-03 | -6.21 | EIF4E_DN | MSigDB lists | EIF4E_DN | 96 | 23 | 17758 | 2279 |
EP400,SIK3,ITPRIP,WDFY3,MYO10,FZD3,PDK4,COL4A3BP,ARHGAP32,CLINT1,ANGPTL4,RANBP2,VPS13C,GATA6,TP53BP1,DCTN4,MKL2,ADAM9,SVIL,UPF2,KIAA0196,TBCK,CASP10 |
| 2.014e-03 | -6.21 | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | MSigDB lists | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | 96 | 23 | 17758 | 2279 |
CYP24A1,FOXO1,TCEB3,GMFB,USP10,MCL1,CLINT1,AARS,PLIN2,PWP1,SLC39A14,CAMK2D,LSS,RBBP8,TP53BP1,ATIC,ATXN2,TNFRSF1A,GTF2H1,ANXA2,PRMT5,NOLC1,HNRNPM |
| 2.025e-03 | -6.20 | GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 197 | 40 | 17758 | 2279 |
ACTG1,ZCCHC8,C1orf50,ABHD6,GBF1,COMMD9,PI4KB,ABCA5,ATIC,CBR4,FGGY,ZNF142,ZFP37,ANP32B,PNMA1,HTRA2,SNAPC5,FDFT1,MIOS,RREB1,PPAT,TLE3,ABCF2,ATG12,RSBN1,DKC1,RDH11,ZFAND3,NME7,NSF,LSM14A,FSCN1,LUC7L3,ARL6IP5,VCAN,MDN1,NCOR1,TSEN2,MORC2,RNF114 |
| 2.031e-03 | -6.20 | Homology Directed Repair | REACTOME pathways | R-HSA-5693538 | 135 | 31 | 8202 | 1117 |
HERC2,RFC4,RFC3,POLK,SIRT6,PARP2,TOP3A,BRCA1,HIST1H4J,HIST1H2BL,RMI1,UBC,RPA1,EXO1,ABL1,BRE,SLX4,BRCA2,RBBP8,PALB2,POLE2,TP53BP1,XRCC2,H2AFX,RAD51B,TIMELESS,ATM,ATRIP,EME1,BRCC3,SPIDR |
| 2.033e-03 | -6.20 | THF_DHG_CYH_2 | prosite domains | PS00767 | 3 | 3 | 11866 | 1504 |
MTHFD2,MTHFD2L,MTHFD1 |
| 2.033e-03 | -6.20 | LETM1_RBD | prosite domains | PS51758 | 3 | 3 | 11866 | 1504 |
LETMD1,LETM1,LETM2 |
| 2.033e-03 | -6.20 | RIO1 | prosite domains | PS01245 | 3 | 3 | 11866 | 1504 |
RIOK1,RIOK2,RIOK3 |
| 2.033e-03 | -6.20 | NOP | prosite domains | PS51358 | 3 | 3 | 11866 | 1504 |
PRPF31,NOP58,NOP56 |
| 2.038e-03 | -6.20 | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | 12 | 6 | 17775 | 2278 |
RNF130,BRAF,NRAS,KIAA1549,GNAI1,CLCN6 |
| 2.041e-03 | -6.19 | TMEM171 (transmembrane protein 171) | protein interactions | 134285 | 53 | 16 | 16036 | 2270 |
MCM10,STX8,ALG6,VPS45,SYMPK,POGZ,TMEM186,NEDD4,DAGLB,LEMD3,INTS5,ORC5,ADGRE5,TNPO3,NAPA,EMSY |
| 2.041e-03 | -6.19 | TIAL1 (TIA1 cytotoxic granule-associated RNA binding protein-like 1) | protein interactions | 7073 | 53 | 16 | 16036 | 2270 |
CUL7,CUL4A,FN1,SCAMP3,CCDC58,COTL1,MBNL1,SBDS,RAB10,RPA1,GADD45A,COPS5,CUL2,SSBP1,COPS6,BMI1 |
| 2.041e-03 | -6.19 | AT_hook | smart domains | SM00384 | 27 | 10 | 9131 | 1249 |
HMGA2,SRCAP,ASH1L,BAZ2A,GLYR1,PDS5B,KMT2C,KMT2A,ZBTB24,DOT1L |
| 2.042e-03 | -6.19 | MORF_PHB | MSigDB lists | MORF_PHB | 119 | 27 | 17758 | 2279 |
TSTA3,DDX18,PRKCSH,LSM12,FAM189B,SFSWAP,WDR18,VARS,BMS1,PARN,POLR2A,ARIH2,MFN2,TERF2IP,PWP1,CAD,RBBP8,CHD3,TP53BP1,TIMM17A,SLC25A11,SCARB1,NFRKB,COPS6,XPO6,TOMM34,MPST |
| 2.050e-03 | -6.19 | SREBP-SCAP-Insig complex | cellular component | GO:0032937 | 3 | 3 | 17570 | 2233 |
INSIG2,INSIG1,SREBF2 |
| 2.050e-03 | -6.19 | eukaryotic translation initiation factor 2 complex | cellular component | GO:0005850 | 3 | 3 | 17570 | 2233 |
EIF2S1,EIF2A,EIF2S2 |
| 2.051e-03 | -6.19 | FBXW11 (F-box and WD repeat domain containing 11) | protein interactions | 23291 | 372 | 73 | 16036 | 2270 |
POLR1A,AARS2,NAT10,SBF2,HLTF,BCOR,UBR5,GBF1,HNRNPA3,PABPC4,AMBRA1,LPIN1,ARMC6,ZKSCAN1,RASSF3,LPIN2,UBAP2L,MRPS27,WIZ,AUP1,FLNC,WDR36,AEBP2,ATF4,AKAP8L,AKAP13,DKC1,SON,PEX1,WARS,GEMIN5,DDX3X,RANBP2,EIF4ENIF1,HNRNPR,PER1,COPS5,IFT140,PUS1,FUS,UTP14A,LARS2,KHDRBS1,GTF2IRD1,MAP1S,SMG7,ZIC2,RCAN1,RBM19,PRPF39,BHLHE40,SPIRE1,NAMPT,NAV1,ZNF326,WDR60,SHMT2,PABPC1,NUDC,KDM5B,MYO10,PPAT,ZC3H18,WWC1,FOXC1,DYNC1H1,EPRS,HELZ,SYNCRIP,KIAA0355,HNRNPH3,MTMR1,STK4 |
| 2.053e-03 | -6.19 | XU_RESPONSE_TO_TRETINOIN_DN | MSigDB lists | XU_RESPONSE_TO_TRETINOIN_DN | 12 | 6 | 17758 | 2279 |
ANXA2,GARS,UBE3A,NR2F2,TPM4,MAD1L1 |
| 2.055e-03 | -6.19 | endometrium-carcinoma-serous_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-serous_carcinoma | 1500 | 229 | 17775 | 2278 |
PTP4A1,SLC37A3,MYCBP2,PHF3,TRIM16,ACTG1,PRKCSH,CNTNAP3,NF1,POLR1A,PLRG1,MKS1,CSPP1,ANKRD18A,BCOR,NBEAL1,SEC16A,UBR5,DST,SLC39A7,PDS5B,HYAL1,SUCLG2,POLE3,KIAA0922,HRG,HCFC2,SRRM2,ETV1,TRIP13,PRKACB,SRPK2,SF3A1,DSC3,DTNB,DPF3,GDAP1,NRAS,OSBP2,SKIV2L2,ITPA,CUX1,ABCC2,BRCA1,KMT2C,DENND4A,SON,CRYBG3,OSBPL1A,SPOP,BSN,TIMM44,GLS,BRCA2,TRRAP,TP53BP1,LSM14A,VPS13D,CSMD3,DNAH2,BLMH,RNF214,SPOCK3,ZMAT3,NMD3,EFNB2,NOMO3,DROSHA,SEC24D,LARS2,CLK1,TRIO,NHS,DLGAP4,FAN1,PIK3R4,FAM192A,RNF141,TOX4,RNF40,DDX56,DHX37,ABCA5,CEP290,PDE10A,ATXN2,CWF19L2,AGL,ATP6V0D1,N4BP2,VOPP1,RANBP6,RREB1,RB1CC1,PRDM16,JMJD1C,RAP1GAP2,KIAA0586,RYR2,SMARCD3,OBSCN,ARID1A,SUPT5H,EHBP1,AGAP1,NR2F1,ATP9B,PWP1,POP1,ASCC3,VPS13C,LRP1B,ITPRIPL1,ATAD5,PDLIM1,UBAP1,HIF1A,FAT1,BIVM,ZCCHC6,TBCK,SRP14,SGSM3,COG5,CPT1C,RTTN,ABCA3,TRERF1,BIRC6,URB2,RIBC2,RBFOX2,HFM1,UROD,NTSR1,EEA1,SEMA6A,URB1,FLNB,IGSF1,ZSCAN5A,VPS18,SHC1,PPFIBP1,CCDC40,TTC3,CEP63,PEG10,ATP6AP1L,DENND1A,CDK12,LYST,TMEM200A,NARS2,GON4L,TFCP2,CPOX,LGALS1,PCNXL2,NUP214,TTC28,DHX57,USP36,ARMC4,KDM4B,KPNA3,ASTN2,ADNP,G6PD,ABHD3,WDR7,PAM,FUS,NFRKB,NOLC1,LAMA5,MID1,PPIL3,PARD3,TNIK,NCOR2,BRAF,SCAMP3,ZNF280C,ARFIP2,RCAN1,ATF7IP,SEMA3E,RSRC1,NEDD4,ABL1,SACS,LRP2BP,IFIT5,ANXA5,NLGN3,AMOT,PLEKHG4,PNMA1,HNRNPM,TOP1,FER1L5,DDX24,WDFY3,AGPAT4,PSPC1,PPP1R21,DHX34,FERMT2,ARHGEF12,C9orf153,GPNMB,UBE2K,PIK3CB,NSD1,PXDN,WDR35,L3MBTL3,HERC1,AGTPBP1,TBX3,DNAJC12,ATM,SVIL,BMP4,IGBP1,XPO6,KIF1B,ANAPC4 |
| 2.057e-03 | -6.19 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | 191 | 39 | 17758 | 2279 |
SLC12A7,MYCBP2,SPRED2,XPC,TTC27,ST6GAL1,SMAD7,MAP1S,NECAP1,SSBP2,MFHAS1,NOP56,SKI,RNF141,AMPD3,MYC,ZEB1,TTC3,POLR1B,PRMT3,SKIV2L,EVL,PDK1,APEX1,GNL3,USP10,PSMG1,POU2F1,IL6R,POLR3A,RERE,TSR1,GADD45A,MBTD1,VPS37B,FNTB,MDN1,NOLC1,IPO4 |
| 2.057e-03 | -6.19 | GSE27786_NKTCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NKTCELL_VS_MONO_MAC_UP | 191 | 39 | 17758 | 2279 |
SARS,PRKCSH,C16orf52,PPP2R2A,SF3A3,MLH1,TIMM10,ZMAT2,MGA,ANAPC1,RPS16,SACS,UBE3A,ARHGAP18,THADA,SUCLG2,GPATCH1,GMDS,ZNRD1,YARS,IPO11,LYST,HN1,PRPF19,TSHZ1,MSI2,DDX24,HARS,VWCE,FRA10AC1,MEX3B,MTHFD1L,RAB10,NME7,ORC5,CNDP2,XPO6,IPO4,GCSH |
| 2.058e-03 | -6.19 | single-stranded RNA binding | molecular function | GO:0003727 | 62 | 17 | 16491 | 2164 |
MSI2,KHDRBS1,AGO2,ATXN1,JMJD6,DDX60,PABPC4,ANXA1,DDX3X,SYNCRIP,LSM14A,IFIT5,DLX2,PABPC1,LONP1,AGO3,DIS3L2 |
| 2.065e-03 | -6.18 | regulation of mRNA processing | biological process | GO:0050684 | 95 | 23 | 16441 | 2138 |
PTCD2,SUPT6H,RBFOX2,SFSWAP,AGO2,JMJD6,SUPT5H,CDC73,HSPA1A,MBNL1,RNF40,PAF1,SNW1,SRSF2,NSRP1,CCNT1,CDK9,CTR9,NCBP2,AHCYL1,PABPC1,PRPF19,SRPK2 |
| 2.086e-03 | -6.17 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 53 | 15 | 17775 | 2278 |
ZNF708,GEMIN5,ELL,IREB2,BRAF,KMT2D,NRAS,SUFU,HLCS,PDK1,ARMC5,RFX2,SMARCA4,BCOR,YTHDF2 |
| 2.087e-03 | -6.17 | REACTOME_DIABETES_PATHWAYS | MSigDB lists | REACTOME_DIABETES_PATHWAYS | 125 | 28 | 17758 | 2279 |
ZBTB17,EXOSC2,ATF4,CUL7,HSPA5,IGF2BP2,SNAP25,PARN,SERP1,HERPUD1,IGF2BP3,EXOC6,SLC30A7,SRPRB,YIF1A,SEC31A,EXOC1,ASNS,SHC1,STX1A,KLF4,EXOC4,EIF2S1,EXOSC4,IGF2BP1,ATP6V0D1,DDIT3,MBTPS2 |
| 2.090e-03 | -6.17 | cellular response to starvation | biological process | GO:0009267 | 112 | 26 | 16441 | 2138 |
FADS1,ATF4,FOXO1,MIOS,UPP1,PDK4,HSPA5,SLC2A1,PIK3R4,ATG12,ATG2B,GAS6,CAV1,SIRT2,TCF7L2,WNT2B,NPRL2,MYBBP1A,ASNS,SREBF2,PMAIP1,ATG7,RRAGA,EIF2S1,SEH1L,TNRC6A |
| 2.093e-03 | -6.17 | RNA_pol_Rpb1_3 | interpro domains | IPR007066 | 3 | 3 | 18293 | 2341 |
POLR1A,POLR2A,POLR3A |
| 2.093e-03 | -6.17 | RIO_kinase_CS | interpro domains | IPR018935 | 3 | 3 | 18293 | 2341 |
RIOK1,RIOK2,RIOK3 |
| 2.093e-03 | -6.17 | RNA_pol_asu | interpro domains | IPR000722 | 3 | 3 | 18293 | 2341 |
POLR1A,POLR2A,POLR3A |
| 2.093e-03 | -6.17 | RNA_pol_Rpb1_4 | interpro domains | IPR007083 | 3 | 3 | 18293 | 2341 |
POLR1A,POLR2A,POLR3A |
| 2.093e-03 | -6.17 | PsdUridine_synth_TruA | interpro domains | IPR001406 | 3 | 3 | 18293 | 2341 |
PUS3,PUS1,PUSL1 |
| 2.093e-03 | -6.17 | Prenylated_rab_accept_PRA1 | interpro domains | IPR004895 | 3 | 3 | 18293 | 2341 |
RABAC1,ARL6IP5,PRAF2 |
| 2.093e-03 | -6.17 | RNA_pol_Rpb1_5 | interpro domains | IPR007081 | 3 | 3 | 18293 | 2341 |
POLR1A,POLR2A,POLR3A |
| 2.093e-03 | -6.17 | USP_C | interpro domains | IPR029346 | 3 | 3 | 18293 | 2341 |
USP7,USP11,USP15 |
| 2.093e-03 | -6.17 | LETM1 | interpro domains | IPR011685 | 3 | 3 | 18293 | 2341 |
LETMD1,LETM1,LETM2 |
| 2.093e-03 | -6.17 | PsdUridine_synth_TruA_a/b_dom | interpro domains | IPR020097 | 3 | 3 | 18293 | 2341 |
PUS3,PUS1,PUSL1 |
| 2.093e-03 | -6.17 | NOSIC | interpro domains | IPR012976 | 3 | 3 | 18293 | 2341 |
PRPF31,NOP58,NOP56 |
| 2.093e-03 | -6.17 | RNA_pol_Rpb1_1 | interpro domains | IPR007080 | 3 | 3 | 18293 | 2341 |
POLR1A,POLR2A,POLR3A |
| 2.093e-03 | -6.17 | PsdUridine_synth_TruA_C | interpro domains | IPR020095 | 3 | 3 | 18293 | 2341 |
PUS3,PUS1,PUSL1 |
| 2.093e-03 | -6.17 | Nop_dom | interpro domains | IPR002687 | 3 | 3 | 18293 | 2341 |
PRPF31,NOP58,NOP56 |
| 2.093e-03 | -6.17 | RNA_pol_N | interpro domains | IPR006592 | 3 | 3 | 18293 | 2341 |
POLR1A,POLR2A,POLR3A |
| 2.093e-03 | -6.17 | PsdUridine_synth_TruA_N | interpro domains | IPR020094 | 3 | 3 | 18293 | 2341 |
PUS3,PUS1,PUSL1 |
| 2.093e-03 | -6.17 | THF_DH/CycHdrlase_CS | interpro domains | IPR020867 | 3 | 3 | 18293 | 2341 |
MTHFD2,MTHFD2L,MTHFD1 |
| 2.095e-03 | -6.17 | chr14q23 | MSigDB lists | chr14q23 | 38 | 12 | 17758 | 2279 |
PRKCH,SLC38A6,GPHN,TRMT5,KIAA0586,RAD51B,FNTB,PLEK2,DLST,DCAF5,ZBTB25,RDH11 |
| 2.102e-03 | -6.16 | genital_tract-germ_cell_tumour-seminoma | COSMIC cancer mutations | genital_tract-germ_cell_tumour-seminoma | 3 | 3 | 17775 | 2278 |
SMARCA4,BRAF,NRAS |
| 2.123e-03 | -6.15 | nuclear chromatin | cellular component | GO:0000790 | 282 | 53 | 17570 | 2233 |
TCF12,EP400,ATRX,TCF3,DPF2,SIRT7,H2AFJ,CSNK2A1,SMARCA4,SIRT2,TNKS1BP1,POGZ,HIST2H2AB,RING1,KDM1A,SFR1,SMARCB1,POLR3D,SLX4,KDM2A,MBD2,UCHL5,BUD31,TIMELESS,RNF2,NRIP1,GATAD2B,BRD4,TRNP1,SIRT6,SMARCD3,ARID1A,HIST1H2BL,APTX,ENC1,PLCB1,FOXC1,TCF7L2,CHAF1A,POLR3G,SMAD3,TRRAP,SMARCC1,EHMT2,E2F4,KLF4,H2AFX,PUS1,NFRKB,NCOR1,EME1,IPO4,KDM4C |
| 2.138e-03 | -6.15 | RNF40 (ring finger protein 40, E3 ubiquitin protein ligase) | protein interactions | 9810 | 58 | 17 | 16036 | 2270 |
WDR61,SUPT6H,SIRT6,CDC73,UBE2E1,CIAPIN1,SFR1,RNF40,PAF1,STX1A,CDK9,WAC,CCDC146,ATM,XPNPEP1,TERF2,USP15 |
| 2.146e-03 | -6.14 | ligand-dependent nuclear receptor transcription coactivator activity | molecular function | GO:0030374 | 52 | 15 | 16491 | 2164 |
TADA3,TRERF1,FGF2,PPARG,PPARGC1B,PSMC3IP,BUD31,MED24,SMARCD3,MED16,PUS1,SRA1,CARM1,KDM1A,SFR1 |
| 2.161e-03 | -6.14 | MORF_EI24 | MSigDB lists | MORF_EI24 | 143 | 31 | 17758 | 2279 |
NCOR2,RFC4,IFRD1,SLC3A2,GARS,SKIV2L2,IDH3G,ALG8,RTN4,MARS,DKC1,XPO7,AARS,ABCF1,SERP1,TARS,HDDC2,NDUFB3,EPRS,NDUFV1,EIF2S2,COQ9,SEC24C,NCBP2,SSBP1,SCARB1,YARS,AP2S1,GNG5,TRIP13,NUDC |
| 2.162e-03 | -6.14 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | 161 | 34 | 17758 | 2279 |
USP7,TNIK,MYCBP2,TTN,EP400,SSH2,ASH1L,FAM13A,PHGDH,FOXP1,SFI1,MTUS1,ATXN7L1,CNST,ASAP1,KIAA0922,TSPAN14,MYB,PDK1,MARCKSL1,ABCC2,HDAC8,PTK2,PDE3B,UBR4,TRRAP,HERC1,RNF138,ATM,PPP3CC,TBL1X,MDN1,SMG1,KAT6A |
| 2.162e-03 | -6.14 | CAIRO_LIVER_DEVELOPMENT_UP | MSigDB lists | CAIRO_LIVER_DEVELOPMENT_UP | 161 | 34 | 17758 | 2279 |
EFNB2,SRM,HMGA2,RWDD1,NPAS2,IGF2BP2,SPATS2,TGFB2,PDZD2,SOCS6,SEMA3D,TTC3,PCOLCE2,MFAP2,SERPINH1,POLR1E,IFRD1,EVL,COL5A2,PTBP2,TSPYL4,WLS,MARCKSL1,SMARCD3,EHBP1,FKBP3,MAK16,FGFR1,NR2F1,KLHL22,PXDN,TBX3,LARGE,RNF138 |
| 2.167e-03 | -6.13 | nucleotide-excision repair | biological process | GO:0006289 | 118 | 27 | 16441 | 2138 |
USP7,GTF2H3,RFC4,POLB,RFC3,CUL4A,XPC,GTF2H2C,POLK,FAN1,LIG4,SUMO3,POLR2A,UBC,RPA1,SLX4,BRCA2,RBBP8,COPS4,COPS3,COPS5,GTF2H1,RNF111,COPS7B,COPS6,OGG1,PRPF19 |
| 2.170e-03 | -6.13 | Znf_C2H2-like | interpro domains | IPR015880 | 800 | 130 | 18293 | 2341 |
ZNF292,ZNF76,ZNF107,ZNF44,ZNF37A,ZNF804A,ZFHX3,IKZF5,JAZF1,HKR1,ZEB1,WIZ,ZNF148,ZNF85,ZNF3,ZNF646,ZBTB17,DPF3,AEBP2,ZNF124,ZNF195,ZNF680,ZNF414,ZSCAN2,ZNF91,ZNF197,GZF1,ZNF622,ZNF266,RBSN,ZNF81,HIC2,ZNF397,ZNF598,ZMAT3,ZNF532,EGR1,ZHX3,DPF2,ZIC2,RLF,RBM20,ZNF358,ZNF354A,ZNF586,ZNF326,ZNF518B,ZNF629,ZNF675,ZNF234,RREB1,ZNF587,PRDM16,ZFP14,ZNF512B,PRDM1,ZNF850,ZNF655,ZNF425,ATXN7,ZBTB12,ZNF160,ZNF430,ZFP90,ZFHX2,ZBTB24,RNF114,ZNF254,ZNF706,ZNF516,TRERF1,ARID2,ZBTB37,ZNF83,ZNF709,ZMAT2,EEA1,ZNF121,ZSCAN5A,ZNF608,ZBTB21,ZNF827,ZKSCAN1,ZNF142,ZFP37,ZNF460,PRMT3,AKAP8L,ZNF480,ZNF251,ZBTB25,IKZF4,ADNP,ZNF333,KLF4,ZNF557,ZNF236,ZNF436,ZNF18,ZBTB11,ZNF589,ZNF507,ZNF786,ZNF280C,SF3A3,MYNN,ZNF346,ZNF691,FOXP1,POGZ,ZNF594,ZNF239,ZNF483,ZNF561,ZNF710,TSHZ1,ZNF821,ZNF654,DHX34,ZNF324B,APTX,ZNF467,KLF6,ZNF407,ZNF221,ZNF708,ZFP62,ZNF155,RNF138,ZNF32 |
| 2.170e-03 | -6.13 | upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma | 1480 | 226 | 17775 | 2278 |
ARHGAP26,ZNF292,PHF3,DPH1,RBM33,UBN1,ATRX,CACNA1H,ANKRD18A,HMOX2,PRKCA,TMEM132A,NUP160,SEC16A,COX10,LPAR3,CUTC,SNAPC4,DST,ANKRD11,PDS5B,TBC1D8,TMPO,FLNC,ACADS,ZBTB17,ZNF124,NRAS,BAZ2A,ZNF414,LIMA1,PTPRM,ALDH1L2,ANK2,NFIA,CUX1,EFHC1,KMT2C,MCM2,KCNH2,DENND4A,PEX1,DOT1L,ZNF622,AHNAK,BRCA2,HLCS,TP53BP1,CHD3,TNFRSF1A,CLU,TMEM158,ZNF532,SYNPO,MTCH1,USP15,HERC2,EP400,DROSHA,STX8,FN1,LARS2,LRRC28,STXBP6,KHDRBS1,PRSS3,DLGAP4,HSD17B10,SMG7,MED13L,DPM3,QSER1,DNAH1,CEP164,SH2B3,PRKCE,NAV1,CEP290,CTR9,SLC16A9,GTF3C3,CALN1,ZCCHC7,PRPS1,AKAP11,FMNL2,ZNF629,LRRC20,USE1,CAMKK2,POLA1,SETD2,KIAA0586,RYR2,OBSCN,IMPDH2,ARID1A,ZNF783,ZNF425,VPS13C,UBAP2,BICD1,KIDINS220,NME7,UBAP1,ZZEF1,FAT1,DNAH17,SDCCAG8,RRAGA,CASS4,IQSEC2,DHCR7,SH3PXD2A,ABCA3,PCNT,ARID2,CELSR3,MYO7A,TMEM177,PTPRG,SLC9B2,HNRNPA3,SEMA6A,GBF1,IGSF1,KDM1A,ZSCAN5A,ZC3H13,CAD,ASNS,SLX4,NBEA,AKNAD1,MET,TMEM14C,TMEM200A,ACSL5,MPP6,BRD4,KMT2D,FAM171A2,LGALS1,GRHL3,LRRC8A,AKAP13,MEF2D,NHSL1,TTC28,UBR4,FGFR1,RAD54B,SMAD3,BAZ1A,ARMC4,RANBP2,KPNA3,YIPF2,SMARCC1,ASTN2,ZNF557,POLR3E,ATG7,INTS9,LARGE,TRAF3,MED20,MDN1,CENPBD1,SMG1,MAPT,DNAJC2,NCOR2,BRAF,TCF3,PDE4B,SF3A3,SOGA1,ANKRD54,NEDD4,SFI1,ABL1,ATXN7L1,NPRL2,SACS,SEC24C,IFIT5,UNC13A,DCTN4,LTN1,HARS2,DDX31,CD44,TTC17,PNMA1,SAMD4A,SPTAN1,FAM98A,FER1L5,PFKFB4,TTLL5,ADAMTSL3,ZFYVE1,WDFY3,PSPC1,ZC4H2,KDM5A,PPP1R21,TEX14,MMAA,RERE,MKX,ETFDH,SRCAP,PXDN,HERC1,SVIL,NFKBIB,POLR1C,ITGB4,RPS6KC1,MMP16,KDM4C,LMBRD2,ZSWIM6,LRRC41 |
| 2.170e-03 | -6.13 | nasopharyngeal_carcinoma | COSMIC cancer mutations | nasopharyngeal_carcinoma | 1480 | 226 | 17775 | 2278 |
ARHGAP26,ZNF292,PHF3,DPH1,RBM33,UBN1,ATRX,CACNA1H,ANKRD18A,HMOX2,PRKCA,TMEM132A,NUP160,SEC16A,COX10,LPAR3,CUTC,SNAPC4,DST,ANKRD11,PDS5B,TBC1D8,TMPO,FLNC,ACADS,ZBTB17,ZNF124,NRAS,BAZ2A,ZNF414,LIMA1,PTPRM,ALDH1L2,ANK2,NFIA,CUX1,EFHC1,KMT2C,MCM2,KCNH2,DENND4A,PEX1,DOT1L,ZNF622,AHNAK,BRCA2,HLCS,TP53BP1,CHD3,TNFRSF1A,CLU,TMEM158,ZNF532,SYNPO,MTCH1,USP15,HERC2,EP400,DROSHA,STX8,FN1,LARS2,LRRC28,STXBP6,KHDRBS1,PRSS3,DLGAP4,HSD17B10,SMG7,MED13L,DPM3,QSER1,DNAH1,CEP164,SH2B3,PRKCE,NAV1,CEP290,CTR9,SLC16A9,GTF3C3,CALN1,ZCCHC7,PRPS1,AKAP11,FMNL2,ZNF629,LRRC20,USE1,CAMKK2,POLA1,SETD2,KIAA0586,RYR2,OBSCN,IMPDH2,ARID1A,ZNF783,ZNF425,VPS13C,UBAP2,BICD1,KIDINS220,NME7,UBAP1,ZZEF1,FAT1,DNAH17,SDCCAG8,RRAGA,CASS4,IQSEC2,DHCR7,SH3PXD2A,ABCA3,PCNT,ARID2,CELSR3,MYO7A,TMEM177,PTPRG,SLC9B2,HNRNPA3,SEMA6A,GBF1,IGSF1,KDM1A,ZSCAN5A,ZC3H13,CAD,ASNS,SLX4,NBEA,AKNAD1,MET,TMEM14C,TMEM200A,ACSL5,MPP6,BRD4,KMT2D,FAM171A2,LGALS1,GRHL3,LRRC8A,AKAP13,MEF2D,NHSL1,TTC28,UBR4,FGFR1,RAD54B,SMAD3,BAZ1A,ARMC4,RANBP2,KPNA3,YIPF2,SMARCC1,ASTN2,ZNF557,POLR3E,ATG7,INTS9,LARGE,TRAF3,MED20,MDN1,CENPBD1,SMG1,MAPT,DNAJC2,NCOR2,BRAF,TCF3,PDE4B,SF3A3,SOGA1,ANKRD54,NEDD4,SFI1,ABL1,ATXN7L1,NPRL2,SACS,SEC24C,IFIT5,UNC13A,DCTN4,LTN1,HARS2,DDX31,CD44,TTC17,PNMA1,SAMD4A,SPTAN1,FAM98A,FER1L5,PFKFB4,TTLL5,ADAMTSL3,ZFYVE1,WDFY3,PSPC1,ZC4H2,KDM5A,PPP1R21,TEX14,MMAA,RERE,MKX,ETFDH,SRCAP,PXDN,HERC1,SVIL,NFKBIB,POLR1C,ITGB4,RPS6KC1,MMP16,KDM4C,LMBRD2,ZSWIM6,LRRC41 |
| 2.175e-03 | -6.13 | embryonic hemopoiesis | biological process | GO:0035162 | 24 | 9 | 16441 | 2138 |
SH2B3,THOC5,HIF1A,PBX1,RUNX1,TGFBR2,KMT2A,STK4,KAT6A |
| 2.180e-03 | -6.13 | mitotic spindle assembly checkpoint | biological process | GO:0007094 | 33 | 11 | 16441 | 2138 |
KLHL22,ANAPC1,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,ATM,MAD2L2,UBE2E1,ANAPC4 |
| 2.180e-03 | -6.13 | cellular senescence | biological process | GO:0090398 | 33 | 11 | 16441 | 2138 |
HMGA2,NSMCE2,TBX3,ARNTL,H2AFX,ID2,CAV1,WNT16,OPA1,TERF2,KAT6A |
| 2.180e-03 | -6.13 | negative regulation of ubiquitin protein ligase activity | biological process | GO:1904667 | 33 | 11 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 2.181e-03 | -6.13 | OTUD1 (OTU deubiquitinase 1) | protein interactions | 220213 | 8 | 5 | 16036 | 2270 |
RIPK1,FLNC,USP11,FLNB,UBC |
| 2.181e-03 | -6.13 | Rassf1 (Ras association (RalGDS/AF-6) domain family member 1) | protein interactions | 56289 | 8 | 5 | 16036 | 2270 |
MAP1S,VAPB,ITPRIP,STK4,TMEM109 |
| 2.181e-03 | -6.13 | LRRC14 (leucine rich repeat containing 14) | protein interactions | 9684 | 8 | 5 | 16036 | 2270 |
COPS6,COPS4,COPS5,COPS3,CUL2 |
| 2.181e-03 | -6.13 | FNDC3B (fibronectin type III domain containing 3B) | protein interactions | 64778 | 8 | 5 | 16036 | 2270 |
TOX4,CAMK2D,RBFOX2,TRIP13,VAC14 |
| 2.181e-03 | -6.13 | FAM219B (family with sequence similarity 219, member B) | protein interactions | 57184 | 8 | 5 | 16036 | 2270 |
SPAG9,ELP2,IKBKAP,TRMU,ELP3 |
| 2.181e-03 | -6.13 | MLH3 (mutL homolog 3) | protein interactions | 27030 | 8 | 5 | 16036 | 2270 |
SHMT2,MSH4,MLH1,MYC,FAN1 |
| 2.187e-03 | -6.13 | WANG_TUMOR_INVASIVENESS_UP | MSigDB lists | WANG_TUMOR_INVASIVENESS_UP | 364 | 66 | 17758 | 2279 |
ACTG1,RPS29,PLOD1,TUBB6,SCAF8,SKI,RPS16,PXK,VCL,HTRA2,ANTXR2,EVL,BRD4,RAB7A,HSPA5,PSMG1,VIM,PNN,PITPNB,FKBP3,EIF3H,ARPC3,PAF1,HNRNPR,PER1,ANXA2,EIF2B3,SMG1,BAG1,TNRC6A,DNAJC2,WDR75,AK2,FN1,B4GALT5,SLK,UBXN1,CCDC47,PIP4K2A,ADH5,SUB1,EIF2S2,ANXA7,TAF3,NISCH,PMPCA,RDX,S100A14,PABPC1,SERBP1,CLK2,LAMC1,TSTA3,C19orf43,ARHGEF12,SUPT5H,EIF5B,UBE2K,ABCF1,KPNA1,RPL28,HIF1A,PEX13,IFITM2,PTP4A2,POLR1C |
| 2.194e-03 | -6.12 | Myb_DNA-binding | pfam domains | PF00249 | 24 | 9 | 16629 | 2165 |
DNAJC2,NCOR2,SMARCC1,DNAJC1,NCOR1,SNAPC4,DMTF1,TERF2,MYB |
| 2.195e-03 | -6.12 | RUTELLA_RESPONSE_TO_HGF_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_DN | 229 | 45 | 17758 | 2279 |
TTN,ADAM19,EGR1,ATRX,ST6GAL1,MED13L,PID1,BCOR,GAS6,LTB4R,DENND3,HDDC2,DDIT4,IQGAP2,NAMPT,C6orf48,DECR1,KIAA0922,MAP3K14,SIK3,TNK2,SETD1B,RAP1GAP2,HOMER2,MARCKSL1,C5AR1,MCL1,SON,NUP214,TCF7L2,HERPUD1,RERE,BATF3,PLIN2,FBXL5,SMAD3,SMARCC1,RPL28,VCAN,CFD,RNF138,IFITM2,TROVE2,MEF2C,LPP |
| 2.196e-03 | -6.12 | negative regulation of synaptic vesicle transport | biological process | GO:1902804 | 3 | 3 | 16441 | 2138 |
BRAF,RAP1A,RAP1B |
| 2.196e-03 | -6.12 | ripoptosome assembly | biological process | GO:0097343 | 3 | 3 | 16441 | 2138 |
RIPK1,SIRT2,CYLD |
| 2.196e-03 | -6.12 | specification of organ position | biological process | GO:0010159 | 3 | 3 | 16441 | 2138 |
BMP4,TBX3,HOXA3 |
| 2.196e-03 | -6.12 | mesodermal cell fate determination | biological process | GO:0007500 | 3 | 3 | 16441 | 2138 |
TRIM15,BMP4,KLF4 |
| 2.196e-03 | -6.12 | ripoptosome assembly involved in necroptotic process | biological process | GO:1901026 | 3 | 3 | 16441 | 2138 |
RIPK1,SIRT2,CYLD |
| 2.196e-03 | -6.12 | negative regulation of synaptic vesicle exocytosis | biological process | GO:2000301 | 3 | 3 | 16441 | 2138 |
BRAF,RAP1A,RAP1B |
| 2.200e-03 | -6.12 | PERK-mediated unfolded protein response | biological process | GO:0036499 | 12 | 6 | 16441 | 2138 |
EIF2S1,ASNS,ATF4,HERPUD1,DDIT3,HSPA5 |
| 2.200e-03 | -6.12 | folic acid-containing compound biosynthetic process | biological process | GO:0009396 | 12 | 6 | 16441 | 2138 |
MTHFD2,GART,MTHFD1L,MTHFD2L,ATIC,MTHFD1 |
| 2.204e-03 | -6.12 | RNA_pol_Rpb1_1 | pfam domains | PF04997 | 3 | 3 | 16629 | 2165 |
POLR1A,POLR2A,POLR3A |
| 2.204e-03 | -6.12 | RNA_pol_Rpb1_2 | pfam domains | PF00623 | 3 | 3 | 16629 | 2165 |
POLR1A,POLR2A,POLR3A |
| 2.204e-03 | -6.12 | RNA_pol_Rpb1_3 | pfam domains | PF04983 | 3 | 3 | 16629 | 2165 |
POLR1A,POLR2A,POLR3A |
| 2.204e-03 | -6.12 | Nop | pfam domains | PF01798 | 3 | 3 | 16629 | 2165 |
PRPF31,NOP58,NOP56 |
| 2.204e-03 | -6.12 | USP7_C2 | pfam domains | PF14533 | 3 | 3 | 16629 | 2165 |
USP7,USP11,USP15 |
| 2.204e-03 | -6.12 | LETM1 | pfam domains | PF07766 | 3 | 3 | 16629 | 2165 |
LETMD1,LETM1,LETM2 |
| 2.204e-03 | -6.12 | PseudoU_synth_1 | pfam domains | PF01416 | 3 | 3 | 16629 | 2165 |
PUS3,PUS1,PUSL1 |
| 2.204e-03 | -6.12 | RNA_pol_Rpb1_4 | pfam domains | PF05000 | 3 | 3 | 16629 | 2165 |
POLR1A,POLR3A,POLR2A |
| 2.204e-03 | -6.12 | PRA1 | pfam domains | PF03208 | 3 | 3 | 16629 | 2165 |
RABAC1,ARL6IP5,PRAF2 |
| 2.204e-03 | -6.12 | RNA_pol_Rpb1_5 | pfam domains | PF04998 | 3 | 3 | 16629 | 2165 |
POLR1A,POLR3A,POLR2A |
| 2.205e-03 | -6.12 | TTGCCAA,MIR-182 | MSigDB lists | TTGCCAA,MIR-182 | 312 | 58 | 17758 | 2279 |
EFNB2,FEM1C,RHOBTB1,PAFAH1B1,RTN4,ZFP36L1,PPIL1,FOXO3,GIT2,PAIP2,DENR,RGS17,ELL,BRE,TBC1D22A,JAZF1,RDX,PRKACB,AUP1,ZCCHC14,PCGF3,BDNF,FGF9,AEBP2,SKAP2,ANK2,FOXN3,FZD3,ARRDC3,GMFB,PCMT1,PCNXL2,ATAT1,ATXN1,CAMSAP2,SATB2,PRDM1,FAM126B,MEF2D,PALLD,MBNL2,EVI5,RAB10,BTBD11,INSIG1,KPNA3,LSM14A,SNAP23,EXOC4,SLC4A7,ABCC3,CNOT6,NFASC,PREPL,MAGI1,FNBP1L,MMP16,MEF2C |
| 2.208e-03 | -6.12 | CA14 (carbonic anhydrase XIV) | protein interactions | 23632 | 44 | 14 | 16036 | 2270 |
RANBP6,EXOC1,THADA,NF1,EXOC6B,AP1M1,FANCD2,LTN1,MON2,HEATR1,EIF2B3,NUP160,XPO6,EXOC6 |
| 2.208e-03 | -6.12 | OXLD1 (oxidoreductase-like domain containing 1) | protein interactions | 339229 | 44 | 14 | 16036 | 2270 |
GLS,NARS2,HVCN1,AUH,PDK1,MTIF2,AARS2,TOP3A,HIBCH,NDUFAF5,PUS1,UQCC1,UQCC2,PDSS2 |
| 2.216e-03 | -6.11 | GRIN2D (glutamate receptor, ionotropic, N-methyl D-aspartate 2D) | protein interactions | 2906 | 35 | 12 | 16036 | 2270 |
PRKCE,ABL1,SYNGAP1,NF1,DLGAP4,DLG4,PPP2R2A,TRAF3,FUS,HSPA1A,NEDD4,SPTAN1 |
| 2.216e-03 | -6.11 | MEF2D (myocyte enhancer factor 2D) | protein interactions | 4209 | 35 | 12 | 16036 | 2270 |
KMT2D,COPS5,SHMT2,SENP3,FUS,MEF2D,PRMT5,MEN1,CDK6,CARM1,MEF2C,SNCA |
| 2.216e-03 | -6.11 | ATP6V1D (ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D) | protein interactions | 51382 | 35 | 12 | 16036 | 2270 |
SEC31A,DDX28,ATP6V1A,CUL2,MPV17,VPS52,ATP6V0A1,PTRH2,XPNPEP1,TOMM34,ATP6V0D1,CIAPIN1 |
| 2.216e-03 | -6.11 | GPN3 (GPN-loop GTPase 3) | protein interactions | 51184 | 35 | 12 | 16036 | 2270 |
POLR3D,POLR1A,POLR3E,GPN1,BRCA1,POLR1B,POLR3B,POLR1C,POLR1E,UBC,POLR3A,POLR2A |
| 2.229e-03 | -6.11 | NOLC1 (nucleolar and coiled-body phosphoprotein 1) | protein interactions | 9221 | 78 | 21 | 16036 | 2270 |
WDR36,SNU13,CUL7,UTP14A,POLR1A,SIRT7,CSNK2A1,RSL1D1,NOP58,PELP1,NOP56,SUB1,DDX56,SPAG9,PTRF,NOP16,E2F4,CEBPZ,RNF2,FBL,SRP14 |
| 2.230e-03 | -6.11 | MODULE_98 | MSigDB lists | MODULE_98 | 384 | 69 | 17758 | 2279 |
TCF12,CSNK2A1,HLTF,NRF1,SRSF2,ZNF85,RAN,CMPK1,ETV1,TRIP13,ZNF646,SAP30,SRPK2,PMS1,RFC4,ZNF124,ATF4,RFC3,ZNF195,RNMT,STAMBP,TSN,PNN,SOX4,SON,DSP,CHAF1A,ZBTB25,SUPT4H1,RBBP8,SMARCC1,HNRNPR,CCNT1,PER1,CEBPZ,H2AFX,FKBP5,BMI1,BLMH,MCM6,EGR1,RCAN1,ZFP36L1,MLH1,TOX4,SNW1,HR,MYC,VPS72,GTF2H1,FBL,CLK2,MSX1,PRIM2,APEX1,POLA1,WBSCR22,LIG4,KLF6,RPA1,KPNA1,POLE2,GADD45A,HIF1A,TAF4,ORC5,NCBP2,NR2F2,ZBTB24 |
| 2.242e-03 | -6.10 | cell junction | cellular component | GO:0030054 | 1147 | 178 | 17570 | 2233 |
ARHGAP26,CGN,ACTG1,UBN1,ENAH,SIRT2,GIT2,DST,PDZD2,RPS16,RAP1A,COPS4,SYN2,CNIH3,MARVELD2,MPST,PTPRK,FLNC,DBN1,DSC3,TNK2,MIOS,LIMA1,PTPRM,CDK4,ANK2,HSPA5,NFIA,AKAP12,CAV1,SH3GL1,CXADR,ARPC3,BSN,PAF1,RHOU,AHNAK,RLTPR,DPP4,ADAM9,MAGI1,NRP1,SYNPO,LPP,CADM4,EFNB2,FBXO45,CLDN15,JUP,TRIP6,OPHN1,NHS,LAMTOR3,SMAD7,EVPL,CD226,ABCA7,NAMPT,MCAM,NRIP1,CAV2,PABPC1,COL17A1,SIGMAR1,HOMER2,RAP1B,UTP15,LIG4,PTPN12,ATAT1,SNAP25,RABAC1,SYT1,TBC1D2,CAT,GRIK4,PDLIM1,FSCN1,SNAP23,FAT1,SRP68,SDCCAG8,CASS4,ADGRE5,IQSEC2,PDLIM5,SH3PXD2A,PRKAR2A,CPT1C,DMXL2,AMOTL1,ASH1L,OLFM2,SLC2A1,RPS29,ACTR3,DDR2,CD99L2,MYH9,HSPA1A,PPP1R9A,FLNB,RPGRIP1L,ESAM,SLX4,JAG1,BCAS2,GRIN2C,PPFIBP1,MMP14,DTNBP1,CORO1A,VCL,DENND1A,PERP,PHLDB2,ARHGAP17,EVL,KIRREL2,DLG4,VIM,PNN,DSP,NUP214,RAB10,TJAP1,SNCA,ARHGAP21,SLC30A3,MISP,COPS5,DNAJA3,ITGA2,RPS6KB1,ARC,NFASC,XRCC4,PARD3,MINK1,MAP1S,PRKCH,SCN1B,PVRL3,DSG2,UNC13A,ANXA5,RDX,NLGN3,S100A14,YBX3,CD44,LDLRAD3,AMOT,PNMA1,SAMD4A,SPTAN1,PPP1R9B,DNMBP,PXN,GPHN,ZC4H2,TPM4,ASAP3,FERMT2,ARHGAP32,PTK2,PALLD,PEAK1,SYMPK,NEU1,HSPA1B,ANXA1,CDH24,DSC2,MPP7,STX1A,SVIL,ITGB4 |
| 2.244e-03 | -6.10 | CDKN1A (cyclin-dependent kinase inhibitor 1A (p21, Cip1)) | protein interactions | 1026 | 284 | 58 | 16036 | 2270 |
BCCIP,NCOR2,CUL4A,MCM10,FOXO1,SUPT6H,ANKRD17,ATP6V1A,NKD2,CENPB,CSNK2A1,SMARCA4,CLINT1,FOXO3,UBR5,HSPA1A,GIGYF2,FLAD1,NPRL2,RPS16,CEP290,PHKA1,MYC,PPFIBP1,WIZ,IGF2BP1,AMOT,CDK6,ANGPT2,ZBTB17,DEAF1,TTLL5,TUBA1A,APEX1,KLHL23,CDK4,HSPA5,SUMO3,VIM,UBR4,TMSB4X,POLR2A,VDR,FBXO21,CAMK2D,DDAH2,TRRAP,GADD45A,HIF1A,SET,WDR73,CCDC85B,TRMT2A,SLC25A11,NCOR1,COPS6,USP11,RNF114 |
| 2.247e-03 | -6.10 | MORF_HEAB | MSigDB lists | MORF_HEAB | 80 | 20 | 17758 | 2279 |
SIK3,CHD9,ATRX,LSM12,KIAA0586,KLHL18,CSNK2A1,TTI1,EIF5B,MFN2,HTR7,TAF2,RANBP2,SLC30A3,RBBP8,CHD3,NCKIPSD,PPIL2,NFRKB,MUTYH |
| 2.250e-03 | -6.10 | endonuclease activity | molecular function | GO:0004519 | 123 | 28 | 16491 | 2164 |
HMGA2,DROSHA,APEX1,AGO2,TSN,TATDN3,FAN1,POP5,EXOG,RNASEH2B,EDC3,ZRANB3,ZC3H12A,EXO1,POP1,RPP30,RBBP8,SLX4,APLF,XRCC2,RAD51B,ALKBH1,EME1,TATDN1,CPSF3,TSEN2,N4BP2,OGG1 |
| 2.255e-03 | -6.09 | KANG_FLUOROURACIL_RESISTANCE_DN | MSigDB lists | KANG_FLUOROURACIL_RESISTANCE_DN | 16 | 7 | 17758 | 2279 |
S100A14,ITGB4,PCK2,FLNB,SLC2A1,DDIT4,SLC43A1 |
| 2.255e-03 | -6.09 | RRNA_METABOLIC_PROCESS | MSigDB lists | RRNA_METABOLIC_PROCESS | 16 | 7 | 17758 | 2279 |
EXOSC2,GEMIN4,FBL,DKC1,NOLC1,NOP58,NOP56 |
| 2.257e-03 | -6.09 | methylenetetrahydrofolate dehydrogenase (NAD+) activity | molecular function | GO:0004487 | 3 | 3 | 16491 | 2164 |
MTHFD2,MTHFD2L,MTHFD1 |
| 2.264e-03 | -6.09 | GCACCTT,MIR-18A,MIR-18B | MSigDB lists | GCACCTT,MIR-18A,MIR-18B | 114 | 26 | 17758 | 2279 |
VMA21,HMBOX1,AEBP2,KDM5B,CRIM1,ARL15,EHMT1,ATXN1,ZFP36L1,IGF2BP2,CAMSAP2,MAP7D1,MEF2D,SON,FAM192A,NAV1,PDZD2,KDM2A,HIF1A,PRICKLE2,PURB,RUNX1,BRWD3,PRKACB,STK4,CLK2 |
| 2.269e-03 | -6.09 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | 192 | 39 | 17758 | 2279 |
EGR1,ACTG1,PSTPIP2,TRIO,ID2,PID1,ZFP36L1,CSTA,RTN1,S100A10,ASAP1,ATG3,ANXA5,PTGS1,ITGAX,PPA1,LYST,SAP30,ACSL5,EVL,TUBA1A,LDHA,LGALS1,RNH1,TMEM123,COTL1,PIK3CB,ANXA1,MTHFD2,PDLIM1,AGTPBP1,VCAN,HK2,APAF1,ANXA2,RBPJ,TBL1X,IFITM2,PTP4A2 |
| 2.269e-03 | -6.09 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | 192 | 39 | 17758 | 2279 |
SEPHS2,SPRED2,MCM10,SUCLG1,ACTG1,HSD17B10,SPATS2L,TUBB6,CSTA,AARS,RMI1,DCTPP1,GART,NUP133,PCK2,TRIP13,HN1,TBC1D8,TMPO,NUDC,MTHFD1,RFC4,RFC3,GINS3,CDK4,POLA1,ATOX1,KIF15,PSMG1,ADSL,IMPDH2,MCM2,WARS,VDR,SLC39A14,POLE2,TRAP1,TP53BP1,MPV17 |
| 2.269e-03 | -6.09 | GSE5960_TH1_VS_ANERGIC_TH1_UP | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_UP | 192 | 39 | 17758 | 2279 |
SPRED2,DDX18,RSL1D1,VARS,SSBP2,CAD,ANAPC1,SUB1,RAP1A,COPS4,MYC,STC2,SUCLG2,SSBP1,MGLL,ZNRD1,SEH1L,CLK2,SCAF11,DEAF1,RFC3,KRT7,POLA1,PSMA1,PSMG1,TRIM37,SLC23A2,RPA1,SEC31A,PES1,RARS,EPRS,IREB2,EHMT2,NSMCE1,PAM,TRMT2A,ZFP90,NOLC1 |
| 2.269e-03 | -6.09 | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | 192 | 39 | 17758 | 2279 |
POLB,AOC3,ZNF516,FEM1C,EGR1,CDC42EP2,PDE4B,ID2,ZFP36L1,TMEM177,RCAN1,SPATS2,PIBF1,HSPA1A,MYC,SLC38A2,RELB,ERRFI1,KDM6B,IFRD1,TRIM13,IL11RA,MARCKSL1,MCL1,ODC1,KLF6,ARL5B,UBC,HERPUD1,HSPA1B,ZC3H12A,ZFP62,SKIL,L3MBTL3,COQ9,ZNF81,RRAGA,CSRNP1,NFKBIB |
| 2.269e-03 | -6.09 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | 192 | 39 | 17758 | 2279 |
TCF12,PTP4A1,NCOR2,AUH,MINK1,ST6GAL1,KIAA0232,SMAD7,RCHY1,MYH9,KIF5C,AP1B1,RPS6KA5,MBNL1,AHCYL2,ANXA7,GRIN2C,ATIC,MCM5,MAP3K14,FXN,NUDC,SPTAN1,ACADS,AKAP8L,ABCC4,TUBA1A,HOMER2,TPM4,ATXN1,PALLD,VDR,DDX3X,GTF2A1,ZZEF1,SLC4A7,ABCC3,RBPJ,TPM1 |
| 2.269e-03 | -6.09 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | 192 | 39 | 17758 | 2279 |
DCTN3,SERINC5,SYT17,CUL7,CUL4A,PTPRA,TRIO,DLGAP4,PRR4,AP1B1,FOXO3,PABPC4,SOCS1,CAMTA2,TBC1D22A,VPS72,TTC3,YARS,LPCAT1,SNAPC5,MPST,EXOSC2,GARS,AKAP8L,ATG9A,PPARG,FOXN3,TBXAS1,PCNXL2,TARS,STOML2,TP53BP1,LSM14A,ADNP,COQ9,CCDC85B,SCARB1,MTMR1,P2RY11 |
| 2.275e-03 | -6.09 | folate transformations I | BIOCYC pathways | HUMAN_PWY-2201 | 8 | 5 | 907 | 131 |
SHMT2,MTHFD2,MTR,ALDH1L2,MTHFD1 |
| 2.280e-03 | -6.08 | DDB1 (damage-specific DNA binding protein 1) | protein interactions | 1642 | 226 | 48 | 16036 | 2270 |
CUL7,CUL4A,MCM10,XPC,SIRT7,UBXN1,SF3A3,RTN4,NUP43,UBR5,AMBRA1,DDIT4,ABL1,SNW1,SLX4,SHC1,COPS4,NUP133,MCM5,COPS3,MYC,BANF1,COPS7B,YARS,FTSJ3,TERF2,MYB,SAP30,RPS6KB2,FLNC,SNU13,APEX1,SIRT6,PSMA1,TOR1AIP2,BRCA1,SAP30BP,POLR2A,UBC,RPA1,PWP1,DYRK1B,COPS5,GPN1,COPS6,DCAF5,PTPN14,RBP1 |
| 2.304e-03 | -6.07 | GSE27786_LSK_VS_BCELL_UP | MSigDB lists | GSE27786_LSK_VS_BCELL_UP | 186 | 38 | 17758 | 2279 |
SLC12A7,PIGN,BTBD2,C10orf2,DYM,PDK4,GTF2IRD1,TUBB6,TOM1L1,CAD,DDX56,IDI1,ARHGAP18,DHX33,NOP16,NISCH,TTC3,GMDS,ALDH18A1,SLC25A23,CEP128,MCEE,TLCD1,EIF4E3,PRIM2,ZNF414,ARHGAP39,SCMH1,EHBP1,MSRA,SMARCC1,POLE2,FDPS,HK2,DNAJC12,PEX13,PDE9A,HRH1 |
| 2.304e-03 | -6.07 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN | 186 | 38 | 17758 | 2279 |
IFT57,SEC24D,MFGE8,SPRYD7,KIF5C,SIRT2,RAC3,PCDH7,ZBED2,NPRL2,ARMC6,SUV39H2,INTS7,LRP2BP,PVRL3,ACOT11,NT5E,FGF9,BDNF,PARP2,MINA,PRDM1,SNAP25,EXOG,TTC28,CXADR,IFT81,TCF7L1,SRCAP,ATAD5,YIPF2,GATA6,SRBD1,LSM14A,ATM,NCBP2,PUS1,MTCH1 |
| 2.304e-03 | -6.07 | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | 186 | 38 | 17758 | 2279 |
SEPHS2,OXNAD1,TTC27,PLRG1,NFX1,GTF2IRD1,C11orf54,NOL3,COX10,REEP5,GIT2,ANKRD54,CTNNBL1,ATG3,C15orf40,SSBP1,CNOT4,YARS,LONP1,MCEE,EXOSC2,ZNF234,RAB7A,SMARCAD1,TEX14,USP10,MTHFD1L,APTX,RBM28,UBE2K,RHOU,WDR5B,PALB2,NSF,SRP68,SIL1,NCOR1,MB21D2 |
| 2.304e-03 | -6.07 | GSE17721_4_VS_24H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_4_VS_24H_GARDIQUIMOD_BMDM_DN | 186 | 38 | 17758 | 2279 |
SRM,SARS,C9orf78,INSIG2,BIRC6,FAM189B,MYO7A,NFX1,C14orf159,SLC6A8,FOXO3,FRRS1,SLC25A20,LPIN2,PRMT5,ACSL5,WDR61,RREB1,PARP2,GPCPD1,CUX1,CAV1,EVI5,CPT1A,TARS,CLNS1A,SPOP,NSD1,RARS,SERF2,PER1,GLG1,USP20,BMI1,FAHD1,NMD3,TNRC6A,TMEM33 |
| 2.317e-03 | -6.07 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | 268 | 51 | 17775 | 2278 |
BRAF,FOXO1,OLFM2,ARID2,TAF1,TTC27,NF1,TRPM6,SMARCA4,ARID1B,ABCA7,SMARCB1,ABL1,DST,SH2B3,ZNF608,SRSF2,SOCS1,ZFHX3,MYC,PDS5B,TTC3,CHD2,KMT2A,NRAS,KMT2D,BRD4,SETD2,RAP1GAP2,PHACTR2,LAMA2,ARID1A,PRDM1,NUP214,TTC28,PHF6,DLEU1,ZNF708,DDX3X,G6PD,BCAS3,ATM,TRAF3,RUNX1,HEATR1,RFXAP,ZNF532,KDM4C,PARD3,MEF2C,LRRC41 |
| 2.319e-03 | -6.07 | CHROMOSOME | MSigDB lists | CHROMOSOME | 120 | 27 | 17758 | 2279 |
RFC4,TTN,RFC3,ATRX,PAFAH1B1,POLA1,NOL6,SUMO3,LIG4,HDAC8,APTX,MCM2,POLG2,FOXC1,RPA1,TERF2IP,ACD,SUV39H2,ZNF330,PAM,PURB,TIMELESS,RAN,XRCC4,TERF2,TOP1,TMPO |
| 2.320e-03 | -6.07 | AAA+_ATPase | interpro domains | IPR003593 | 144 | 31 | 18293 | 2341 |
RFC4,RFC3,ABCA3,ABCC4,KATNAL1,ABCF2,BCS1L,ABCC2,MMAA,ABCF1,MCM9,PEX1,ABCA7,DYNC1H1,ASCC3,ATAD5,NAV1,ABCA12,NVL,NSF,ABCA5,RAD51B,GPN1,ABCC3,DNAH2,DYNC2H1,MDN1,TRIP13,LONP1,VWA8,NAV3 |
| 2.327e-03 | -6.06 | regulation of cell cycle phase transition | biological process | GO:1901987 | 277 | 53 | 16441 | 2138 |
HMGA2,CUL4A,ANKRD17,XPC,TCF3,PLRG1,CSNK2A1,SMARCA4,PBX1,ID2,PID1,PPP1R1C,SIRT2,RNASEH2B,GIGYF2,CDC73,PSMF1,MAD2L2,ANAPC1,NEK6,ANAPC11,TRIAP1,ANAPC10,MAD1L1,RDX,FBXO31,LSM10,CTC1,PRPF19,PPP1R9B,BRD4,CRADD,FOXN3,CDK4,TEX14,SMARCD3,PSMA1,TPRA1,MEN1,SOX4,PLCB1,UBC,UBE2E1,ZNF655,ANXA1,DDX3X,CAMK2D,KLHL22,CDC16,NSMCE2,RAD51B,ATM,ANAPC4 |
| 2.336e-03 | -6.06 | GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP | MSigDB lists | GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP | 180 | 37 | 17758 | 2279 |
NCOR2,MYCBP2,CCDC58,PID1,RLF,SAFB2,BIRC2,DHX35,SCAF8,CHD7,KIAA1958,BRE,PUS3,SLC39A7,SSBP1,B3GNTL1,CEP63,TOMM34,SNX29,MSI2,KAT8,SKAP2,SFSWAP,GPCPD1,ARHGEF10,LAMA2,LENG8,FOXC1,TARS,ZNF655,PAF1,LUC7L3,POLR3E,DNAH17,DISP1,WDR66,TNRC6A |
| 2.342e-03 | -6.06 | KEGG_RNA_POLYMERASE | MSigDB lists | KEGG_RNA_POLYMERASE | 29 | 10 | 17758 | 2279 |
POLR3D,POLR1A,POLR3B,POLR1B,POLR1C,ZNRD1,POLR1E,POLR3A,POLR2A,POLR3G |
| 2.345e-03 | -6.06 | negative regulation of mitotic sister chromatid segregation | biological process | GO:0033048 | 38 | 12 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 2.345e-03 | -6.06 | negative regulation of mitotic sister chromatid separation | biological process | GO:2000816 | 38 | 12 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 2.346e-03 | -6.06 | POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 64 | 17 | 17758 | 2279 |
ATF4,FOXO1,NPAS2,PPARGC1B,SUPT5H,FOXO3,BMP6,SMAD3,SUPT4H1,HIF1A,ARNTL,MKL2,TNFRSF1A,GTF2H1,RUNX1,NRIP1,MAML3 |
| 2.361e-03 | -6.05 | ELVIDGE_HYPOXIA_BY_DMOG_UP | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_UP | 126 | 28 | 17758 | 2279 |
KLHL24,ZNF292,INSIG2,RBCK1,PDK1,EGR1,SLC2A1,AKAP12,ATXN1,CAV1,BHLHE40,FAM13A,PRKCA,RLF,KLF6,ANGPTL4,DDIT4,DST,DSC2,SRD5A3,STC2,GPR87,AHNAK2,PAM,HK2,MET,YEATS2,SAMD4A |
| 2.361e-03 | -6.05 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | 126 | 28 | 17758 | 2279 |
KDM6B,PTP4A1,SIK3,IFRD1,CLK1,SETD2,JMJD1C,ID2,MYNN,MCL1,OPA1,FOSL2,SON,FOXP1,KLF6,NAMPT,DDX3X,CNST,IKZF5,GADD45A,PMAIP1,PER1,KLF4,CSRNP1,CHD2,PTP4A2,CSGALNACT2,ZBTB24 |
| 2.365e-03 | -6.05 | ROME_INSULIN_TARGETS_IN_MUSCLE_DN | MSigDB lists | ROME_INSULIN_TARGETS_IN_MUSCLE_DN | 174 | 36 | 17758 | 2279 |
ARHGAP26,LETM1,NF1,SESTD1,VPS45,TRIM15,PLEK2,TGFB2,SLC6A8,FAM13A,UBTD2,FOXO3,EDC3,ABCA7,DOPEY1,RGS17,RNFT2,WIZ,PXK,ZNF518B,PCSK6,GATAD2B,DEAF1,BRD4,WDR61,MEF2D,ARHGAP32,VPS53,NCDN,ZNF197,CDC16,HLCS,ARL13B,CSRNP1,SLCO5A1,TESC |
| 2.365e-03 | -6.05 | GSE25087_TREG_VS_TCONV_FETUS_DN | MSigDB lists | GSE25087_TREG_VS_TCONV_FETUS_DN | 174 | 36 | 17758 | 2279 |
KLHL24,SNX27,AK2,TCF3,ID2,NUP43,C11orf54,RPAIN,RING1,MTUS1,NDUFB3,SRPRB,CHD7,C6orf48,ZNHIT6,C12orf76,PRMT5,MAP3K12,SLC25A23,VCL,FXN,SFSWAP,PRDM16,NFIA,LDHA,PTK2,POLG2,TCF7L2,GZF1,PLIN2,HK2,INTS9,TNFRSF1A,PUS1,TSEN2,NOLC1 |
| 2.372e-03 | -6.04 | COP9 signalosome | cellular component | GO:0008180 | 34 | 11 | 17570 | 2233 |
AMOTL1,COPS4,COPS3,COPS5,NCKIPSD,HSPA5,MYH9,COPS7B,COPS6,AMOT,STOML2 |
| 2.377e-03 | -6.04 | medullomyoblastoma | COSMIC cancer mutations | medullomyoblastoma | 499 | 86 | 17775 | 2278 |
SYT17,TRERF1,CELSR3,TNFRSF21,SMARCA4,GYG1,ST3GAL6,FAM13A,TNKS1BP1,SEMA6A,PABPC4,KDM1A,CHD7,DST,NRF1,NVL,PPFIBP1,DNAJB6,ANKRD11,C16orf58,INTS12,CORO1A,CEP128,VPS13B,KDM3B,KAT8,PRAME,PHLDB2,KMT2D,COL5A2,RNMT,PARP2,EHMT1,GNG7,WDPCP,EFHC1,NUP214,DDX60,PDE8B,EXO1,DDX3X,CAMK2D,TRRAP,SUFU,CCDC146,CSMD3,RUNX1,NFRKB,NRP1,USP11,SMG1,SULT1C2,SUPT6H,EVPL,DNAH1,TECTA,FAM50A,HR,CTR9,GREB1,UPF2,TSHZ1,WDFY3,WDR25,RYR2,RABAC1,ZNF407,SLC26A11,DNAH14,ZNF221,DYNC1H1,SYCP2L,BAZ2B,LRP1B,IREB2,SYNCRIP,FAT1,HK2,SVIL,MYOM2,ZRANB2,GPAM,NCOR1,MIPOL1,KDM4C,HRH1 |
| 2.377e-03 | -6.04 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma | 499 | 86 | 17775 | 2278 |
SYT17,TRERF1,CELSR3,TNFRSF21,SMARCA4,GYG1,ST3GAL6,FAM13A,TNKS1BP1,SEMA6A,PABPC4,KDM1A,CHD7,DST,NRF1,NVL,PPFIBP1,DNAJB6,ANKRD11,C16orf58,INTS12,CORO1A,CEP128,VPS13B,KDM3B,KAT8,PRAME,PHLDB2,KMT2D,COL5A2,RNMT,PARP2,EHMT1,GNG7,WDPCP,EFHC1,NUP214,DDX60,PDE8B,EXO1,DDX3X,CAMK2D,TRRAP,SUFU,CCDC146,CSMD3,RUNX1,NFRKB,NRP1,USP11,SMG1,SULT1C2,SUPT6H,EVPL,DNAH1,TECTA,FAM50A,HR,CTR9,GREB1,UPF2,TSHZ1,WDFY3,WDR25,RYR2,RABAC1,ZNF407,SLC26A11,DNAH14,ZNF221,DYNC1H1,SYCP2L,BAZ2B,LRP1B,IREB2,SYNCRIP,FAT1,HK2,SVIL,MYOM2,ZRANB2,GPAM,NCOR1,MIPOL1,KDM4C,HRH1 |
| 2.379e-03 | -6.04 | tetrahydrofolate metabolic process | biological process | GO:0046653 | 20 | 8 | 16441 | 2138 |
MTHFD2,GART,ATIC,ALDH1L2,SHMT2,MTHFD1L,MTHFD2L,MTHFD1 |
| 2.389e-03 | -6.04 | MARTINEZ_RB1_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_TARGETS_UP | 648 | 108 | 17758 | 2279 |
TCF12,GGT1,NDUFA5,SLC48A1,RBFOX2,PDK4,C16orf45,SMARCA4,PLEK2,CCNL2,PTPRG,SAFB2,UBL5,PDE3A,MGA,LPIN1,RIOK2,PRKD3,BRE,S100A10,RASSF3,UBAP2L,INTS12,ZNF148,KIAA0922,MSH4,MGLL,PRKACB,TRIP13,ACSL5,DSC3,CUX1,LGALS1,PITPNB,SOX4,ENC1,KRTCAP2,NHSL1,ERC1,SERP1,CLNS1A,WARS,SNCA,DDX3X,MSRA,SH3RF1,HIPK2,G6PD,CFD,PTPN14,HMGA2,CARS,MIF4GD,MCM6,CLDN15,CLK1,NKD2,RTN4,CHCHD10,OPA1,TGFBR2,FOXP1,NEDD4,SLC39A11,HR,SDCBP2,CTR9,ARHGAP1,CD44,ERRFI1,PRMT5,CAV2,NT5E,PCSK6,SCAF11,CAMKK2,AP4S1,SIGMAR1,LSM12,CRIM1,PCCA,ELOVL6,IDH3G,WWC1,PLCB1,FOXC1,POLR3A,UBC,PGD,RPA1,RDH11,CAT,MGAT2,ETFDH,NME7,PMEPA1,NSF,FGFBP1,FSCN1,ACOX1,STX18,RIOK3,PURB,ATM,PEX13,PSAP,PDLIM5,RNF114 |
| 2.392e-03 | -6.04 | RFC2 (replication factor C subunit 2) | protein interactions | 5982 | 49 | 15 | 16036 | 2270 |
RFC4,PMS1,RFC3,BRD4,RAD18,GINS3,TP53BP1,COPS5,MYC,SMARCAD1,USP20,BRCA1,UBC,RPA1,NT5E |
| 2.392e-03 | -6.04 | BRCC3 (BRCA1/BRCA2-containing complex subunit 3) | protein interactions | 79184 | 49 | 15 | 16036 | 2270 |
USP7,BRE,SPAG9,BRCA2,GPHN,HNRNPR,COPS5,WDHD1,SHMT2,BRCA1,BRCC3,MCM2,SNAPC5,UBC,SF3A1 |
| 2.406e-03 | -6.03 | GTGCCAT,MIR-183 | MSigDB lists | GTGCCAT,MIR-183 | 162 | 34 | 17758 | 2279 |
TCF12,RAB11FIP4,EGR1,FOXO1,CELSR3,RHOBTB1,PPP2R2A,ENAH,PRKCA,KCNJ14,FOXP1,MBNL1,SACS,SRSF2,ZDHHC6,ZMYM2,GNG5,SOX6,TMPO,GATAD2B,PHLDB2,VPS37A,SERP1,PHF6,IRS1,DAGLA,ARHGAP21,KIAA0355,L3MBTL3,RNF138,PAM,PTPN4,TPM1,MEF2C |
| 2.410e-03 | -6.03 | response to gamma radiation | biological process | GO:0010332 | 53 | 15 | 16441 | 2138 |
POLB,TRIM13,BRCA2,EGR1,MYC,XRCC2,TMEM109,FANCD2,H2AFX,LIG4,ATM,CAV1,IL6R,MEN1,KDM1A |
| 2.431e-03 | -6.02 | AAGGGAT,MIR-188 | MSigDB lists | AAGGGAT,MIR-188 | 75 | 19 | 17758 | 2279 |
EFNB2,CGN,PHF3,PDE4A,LUZP1,LSM12,ELOVL6,ATXN1,PHACTR2,IGF2BP2,SOX4,MBNL1,KPNA3,TRIAP1,BUD31,RNF111,NBEA,SELT,MEF2C |
| 2.434e-03 | -6.02 | preribosome | cellular component | GO:0030684 | 49 | 14 | 17570 | 2233 |
PES1,WDR36,ZNF622,MPHOSPH10,UTP14A,UTP15,NOL6,SRFBP1,HEATR1,FBL,PDCD11,NOP58,FTSJ3,NOP56 |
| 2.436e-03 | -6.02 | BASAKI_YBX1_TARGETS_DN | MSigDB lists | BASAKI_YBX1_TARGETS_DN | 359 | 65 | 17758 | 2279 |
PTP4A1,DMXL2,CNTNAP3,ATRX,RSL1D1,COBLL1,SBF2,ST3GAL6,FAM13A,PPP1R9A,MMP7,CCDC50,ARHGAP18,PDS5B,TTC3,MET,ZMYM2,CDK12,VPS13B,MALL,TRIM13,PDK1,TFPI,GDPD1,MARCKSL1,SGK2,CXADR,TAF9B,HLA-DMA,KDM4B,BDH2,DPP4,ZNF397,KLHL24,PGPEP1,SULT1C2,EGR1,RSF1,BHLHE40,CLINT1,SLC1A1,DDIT4,NAV1,NEBL,SLC7A11,ABCA5,PTGS1,DYNC2H1,NT5E,PCSK6,MSI2,NAA38,SLC40A1,RDH10,MMAA,CAT,BICD1,BAZ2B,HELZ,HK2,ATM,SH3PXD2A,PDE9A,LMBRD2,N4BP2L2 |
| 2.436e-03 | -6.02 | positive regulation of transcription from RNA polymerase I promoter | biological process | GO:0045943 | 16 | 7 | 16441 | 2138 |
SMARCA4,UBTF,HEATR1,ATF4,DHX33,UTP15,SMARCB1 |
| 2.445e-03 | -6.01 | GPROTEINBRPT | prints domains | PR00320 | 84 | 17 | 4759 | 462 |
GNB3,WDR61,PAFAH1B1,WDR18,PLRG1,WDR37,NLE1,GEMIN5,PWP1,PEX7,WDR5B,PAK1IP1,PRPF4,TBL1X,APAF1,SEH1L,PRPF19 |
| 2.459e-03 | -6.01 | PBX2 (pre-B-cell leukemia homeobox 2) | protein interactions | 5089 | 31 | 11 | 16036 | 2270 |
DCTN3,SKIV2L2,PBX1,SHMT2,CENPBD1,COPS6,IKBKAP,RPS6KC1,SMYD3,PKNOX1,UBE2E1 |
| 2.464e-03 | -6.01 | nuclear replication fork | cellular component | GO:0043596 | 39 | 12 | 17570 | 2233 |
MCM10,BCAS2,POLE2,POLA1,SMARCAD1,PLRG1,PURB,POLE3,ZRANB3,TOP1,RPA1,PRPF19 |
| 2.467e-03 | -6.00 | human chr12q13.12 | chromosome location | human chr12q13.12 | 37 | 10 | 26250 | 2590 |
PRPF40B,DDN,FMNL3,KMT2D,LMBR1L,TUBA1A,CERS5,LETMD1,SPATS2,DNAJC22 |
| 2.474e-03 | -6.00 | SYNCRIP (synaptotagmin binding, cytoplasmic RNA interacting protein) | protein interactions | 10492 | 170 | 38 | 16036 | 2270 |
HMGA2,CUL7,LETM1,FN1,KHDRBS1,SIRT7,MAP1S,PCSK7,TMEM177,IKBIP,HNRNPA3,RNF2,IGF2BP1,SRRM2,PABPC1,HNRNPM,TIMM50,SNU13,SIRT6,SYT1,FKBP3,UBC,RPA1,DOT1L,STOML2,DDX3X,EPRS,LSM14A,HNRNPR,SNAP23,COPS5,CDK9,CUL2,H2AFX,NCBP2,FUS,COPS6,ZNF598 |
| 2.476e-03 | -6.00 | V$CREBP1_Q2 | MSigDB lists | V$CREBP1_Q2 | 243 | 47 | 17758 | 2279 |
OXNAD1,BRAF,ID1,EGR1,NF1,MAP3K13,PAFAH1B1,DDX19A,OSBPL9,PPP2R2A,RCAN1,MBNL1,RING1,MCAM,SUV39H2,LETM2,GLYR1,VGF,IKBKB,SLC38A2,JOSD1,CTC1,AGPAT4,TPM4,GNL1,SNAP25,MARCH6,GSTCD,DLST,NUP214,TMEM175,ERC1,DDX3X,RANBP2,IFT81,MSX2,RBBP8,GTF2A1,UBAP1,TRAP1,ZZEF1,PER1,VPS37B,HOXA3,ADAM9,NAPA,ZBTB11 |
| 2.476e-03 | -6.00 | V$CEBPGAMMA_Q6 | MSigDB lists | V$CEBPGAMMA_Q6 | 243 | 47 | 17758 | 2279 |
UNC13D,SSH2,BRAF,TRERF1,SCAMP3,NF1,OSBPL9,PTPRG,CHD5,SEMA6A,NEDD4,CTNNBL1,NSRP1,PAK1IP1,MGLL,CDK6,PABPC1,NAV3,TMPO,SOBP,NRAS,NR6A1,SLC38A1,PPARG,NPM3,FOXN3,JMJD1C,PSMA1,MRRF,MARS,PRDM1,PTK2,UBE2K,NR2F1,C1orf122,DDAH2,NSD1,SPAG9,GSTO2,SRP68,LUC7L3,HOXA3,ALKBH1,PPP1R12B,MID1,MEF2C,HS2ST1 |
| 2.499e-03 | -5.99 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_UP | 193 | 39 | 17758 | 2279 |
CARS,CSPP1,CSNK1A1,PDCD5,SBDS,NDUFV1,ASNS,NUP133,PVRL3,PPIL2,SNTG2,BUD31,DTNBP1,KDM5C,CELF1,LSM10,FTSJ3,C18orf21,ARHGAP17,ATF4,RREB1,CRIM1,CPOX,PACRGL,C5AR1,APTX,YTHDF2,ZFP62,TPD52L2,POLE2,PURB,TMEM219,DIRAS1,ASB3,COPS6,MAGI1,BRWD3,IGBP1,STK4 |
| 2.499e-03 | -5.99 | GSE3982_MAST_CELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NEUTROPHIL_UP | 193 | 39 | 17758 | 2279 |
TCF12,WDR74,NAT10,PID1,SSR4,LYRM2,MGA,LPIN1,NUP133,MYC,BANF1,PIGG,NOC3L,ERI3,AVEN,YARS,PRPS1,PNMA1,SEH1L,FAM127A,PDE4A,PCMT1,MINA,AKAP12,C11orf49,LSG1,FKBP3,PIK3CB,ANXA1,YTHDF2,RARS,HERC1,FAT1,POLR3E,WDR7,SQLE,PUS1,EIF2B3,NOLC1 |
| 2.509e-03 | -5.99 | TSENG_IRS1_TARGETS_UP | MSigDB lists | TSENG_IRS1_TARGETS_UP | 109 | 25 | 17758 | 2279 |
LAMA4,CARS,EFNB2,DBN1,SLC3A2,NARS,DDX18,ACTR3,FERMT2,BMP6,PAG1,NR2F1,NOP56,RHOU,TRIB3,ASNS,MTHFD2,COPS5,ZDHHC6,SQLE,SLC35C2,YARS,DDIT3,SF3A1,MEF2C |
| 2.520e-03 | -5.98 | Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | REACTOME pathways | R-HSA-428359 | 3 | 3 | 8202 | 1117 |
IGF2BP2,IGF2BP1,IGF2BP3 |
| 2.522e-03 | -5.98 | tRNA methyltransferase activity | molecular function | GO:0008175 | 20 | 8 | 16491 | 2164 |
METTL1,TRMT5,TRMT13,TRMU,ALKBH8,METTL2A,FTSJ1,METTL2B |
| 2.528e-03 | -5.98 | CHD4 (chromodomain helicase DNA binding protein 4) | protein interactions | 1108 | 110 | 27 | 16036 | 2270 |
GATAD2B,CUL7,BRD4,PCNT,SIRT6,SMARCAD1,SIRT7,CSNK2A1,SMARCA4,CHD5,KDM1A,UBC,USP36,PHF6,RPA1,UBTF,SUB1,IKZF4,SMARCC1,CHD3,MYC,BANF1,ATM,RNF2,NOLC1,BMI1,SAP30 |
| 2.539e-03 | -5.98 | SF3A1 (splicing factor 3a, subunit 1, 120kDa) | protein interactions | 10291 | 148 | 34 | 16036 | 2270 |
SART1,MCM6,CUL7,UTP14A,PRPF31,RBFOX2,PLRG1,SIRT7,SF3A3,CSNK2A1,TOX4,MCM5,ZNF326,RNF2,SSBP1,SRRM2,PABPC1,HNRNPM,PRPF19,SKIV2L2,TRA2A,ZC3H18,ATG12,RPA1,DYNC1H1,SMAD3,SMARCC1,HNRNPR,PRPF4,NCOR1,FUS,BRCC3,FNBP1L,ZMAT3 |
| 2.542e-03 | -5.97 | GSE17721_LPS_VS_CPG_4H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDM_DN | 187 | 38 | 17758 | 2279 |
TCF12,PTCD2,SARS,DDX18,CCDC47,AARS,PAG1,IGF2BP3,ADH5,FAM50A,RAP1A,PHF5A,SREBF2,NOP16,DNAJB6,TRIAP1,ZDHHC6,IPP,TSPAN14,LSM10,PEA15,PARP2,GMFB,EVI5,C19orf70,DHX57,KIF16B,LSS,TSR1,SLC30A3,COQ9,DNAJA3,MPV17,SVIL,SQLE,SLC25A19,DDX10,DDIT3 |
| 2.542e-03 | -5.97 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | 187 | 38 | 17758 | 2279 |
SLC37A3,ASCC1,PIGM,C17orf80,CAMK1,DCP1B,PPIL1,SLC29A1,HLTF,NOL3,AARS,YARS2,IGF2BP3,RAP1A,IDI1,S100A10,DNAJB6,FGGY,HIRIP3,SERPINH1,GMDS,FUT11,CEP128,MTHFD1,FAM98A,FAM127A,CLYBL,HOMER2,PSMG1,GPNMB,CYB5B,EXO1,OXSR1,TRIB3,ASTN2,PAM,ATG7,FNTB |
| 2.542e-03 | -5.97 | VEGF_A_UP.V1_DN | MSigDB lists | VEGF_A_UP.V1_DN | 187 | 38 | 17758 | 2279 |
EPM2AIP1,CDC42EP2,B4GALT5,DBF4,POP5,PCDH7,RAP1A,SACS,ARMC6,PHKA1,ATIC,TRMU,MMP14,PRMT3,PRKACB,ANGPT2,TMPO,SCAF11,RFC4,ZNF124,TLE3,PNN,NR2F1,DKK1,RDH11,BAZ1A,EXO1,POP1,GATA6,ITGA2,CEBPZ,SLC4A7,ADAM9,FKBP5,MDN1,NRP1,XRCC4,CEP170 |
| 2.542e-03 | -5.97 | TAF7 (TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa) | protein interactions | 6879 | 40 | 13 | 16036 | 2270 |
TAF2,VDR,TRRAP,TAF1,CCNT1,TAF3,CDK9,TAF4,CSNK2A1,TRIM22,TAF12,SETD7,TAF9B |
| 2.542e-03 | -5.97 | HBB (hemoglobin, beta) | protein interactions | 3043 | 40 | 13 | 16036 | 2270 |
GDAP1,HBG2,PGPEP1,FAM189B,UCHL5,COPS3,GDPD1,SMG7,SELT,NDUFAF5,UPF2,PABPC1,POLR2A |
| 2.554e-03 | -5.97 | NOSIC | smart domains | SM00931 | 3 | 3 | 9131 | 1249 |
PRPF31,NOP58,NOP56 |
| 2.554e-03 | -5.97 | RPOLA_N | smart domains | SM00663 | 3 | 3 | 9131 | 1249 |
POLR1A,POLR2A,POLR3A |
| 2.555e-03 | -5.97 | salivary_gland-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenoid_cystic_carcinoma | 507 | 87 | 17775 | 2278 |
SLC37A3,SDSL,CYLD,CELSR3,BCOR,PTPRG,CORO6,STAM,DDX60L,PLXNB1,MGA,PHC2,PDZD2,ZFHX3,ACD,FGGY,SLC38A2,RNF111,MET,CEP135,ZMYM2,TRIP13,MAML3,PTPRK,SEC24A,CHD9,NRAS,SSFA2,HARS,SIRT6,ARRDC3,ADAM32,BRCA1,KMT2C,ENC1,EDEM2,TMEM206,GEMIN5,AHNAK,TRRAP,RUNX1,MAGI1,TRIM36,ZNF507,HMGA2,BRAF,ANKRD17,KHDRBS1,PAX2,SF3A3,ZFP36L1,ATF7IP,IKBKAP,RLF,C1orf50,ENOX1,CD226,FOXO3,ABCA7,RNF40,DHX37,ATXN2,LARP4B,ANGPT2,KDM6B,AGPAT4,ARID5B,JMJD1C,TYW1,RAP1B,RYR2,OBSCN,RSBN1,PDE3B,EXOC6,ZNF783,PXDN,BICD1,TMEM237,DAGLB,ZZEF1,DNAJC12,ATM,MYOM2,MAP2K4,ARHGAP10,GPATCH4 |
| 2.556e-03 | -5.97 | TRANSCRIPTION_COREPRESSOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_COREPRESSOR_ACTIVITY | 92 | 22 | 17758 | 2279 |
NCOR2,APEX1,RBFOX2,PLRG1,BCOR,TRIM22,BATF3,SKIL,NSD1,TRIB3,SUFU,JAZF1,HIPK2,RELB,ZEB1,NCOR1,ZNF85,NR2F2,NRIP1,DDIT3,CASP8AP2,SAP30 |
| 2.556e-03 | -5.97 | MODULE_182 | MSigDB lists | MODULE_182 | 92 | 22 | 17758 | 2279 |
WDR75,BRAF,NRAS,MIOS,DBF4,MARCH6,OPA1,RLF,SEC16A,PIBF1,DDX49,STK10,C1orf159,PMAIP1,INTS7,SEC24C,DNAJA3,AEN,NCOR1,NMD3,MICAL3,STK4 |
| 2.563e-03 | -5.97 | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma | 334 | 61 | 17775 | 2278 |
ARHGAP26,AMOTL1,BRAF,CYLD,ACTG1,XPC,KIF5A,DPF2,FANCD2,MAPK8IP3,TRPM6,CACNA1H,ZNF107,ARID1B,DDX60L,HAS3,YLPM1,GLYR1,IKBKB,WAC,RAPGEFL1,KIAA0922,MTHFD2L,PRKACB,MAML3,PTPRK,KLRD1,ACSL5,TSHZ1,FLNC,DDX28,DTNB,EIF4E3,KMT2D,STAG1,RREB1,FZD3,GRHL3,OBSCN,TBRG4,PHACTR2,ZNFX1,ARID1A,TRIM37,SLC9A5,CRYBG3,SYMPK,LSG1,KIF16B,CDH24,LRP1B,TRRAP,ELP2,SERINC1,SPEN,FAT1,CSMD3,ABCC3,TRAF3,DISP1,PTPN14 |
| 2.586e-03 | -5.96 | response to X-ray | biological process | GO:0010165 | 29 | 10 | 16441 | 2138 |
BRCA2,TP53BP1,PMAIP1,XRRA1,XRCC2,LIG4,BRCC3,IKBIP,XRCC4,ANXA1 |
| 2.590e-03 | -5.96 | human chr3p22 | chromosome location | human chr3p22 | 7 | 4 | 26250 | 2590 |
SLC4A7,VIPR1,TGFBR2,CSRNP1 |
| 2.590e-03 | -5.96 | human chr18q22.2 | chromosome location | human chr18q22.2 | 7 | 4 | 26250 | 2590 |
RTTN,LOC101060542,LOC101927481,SOCS6 |
| 2.590e-03 | -5.96 | MYOD1 (myogenic differentiation 1) | protein interactions | 4654 | 84 | 22 | 16036 | 2270 |
NCOR2,IFRD1,ID1,CDK4,TCF3,SMAD7,ID2,SMARCD3,PBX1,SMARCA4,BHLHE40,SETD7,PRKCA,SMAD3,SNW1,KPNA3,NCOR1,RUNX1,NR2F2,PRMT5,CARM1,MEF2C |
| 2.596e-03 | -5.95 | focal adhesion | cellular component | GO:0005925 | 390 | 69 | 17570 | 2233 |
ARHGAP26,ACTG1,ACTR3,RPS29,DDR2,MYH9,CD99L2,ENAH,GIT2,HSPA1A,FLNB,DST,RPS16,PPFIBP1,MMP14,VCL,FLNC,PHLDB2,EVL,LIMA1,HSPA5,AKAP12,VIM,CAV1,NUP214,RAB10,ARPC3,RHOU,AHNAK,MISP,ITGA2,DPP4,ADAM9,NFASC,NRP1,LPP,EFNB2,JUP,TRIP6,LAMTOR3,NHS,MCAM,ANXA5,RDX,CD44,PABPC1,PNMA1,CAV2,PXN,TPM4,ASAP3,PTPN12,ATAT1,LIG4,FERMT2,PTK2,PALLD,PEAK1,HSPA1B,ANXA1,CAT,PDLIM1,SRP68,FAT1,SNAP23,ADGRE5,CASS4,SVIL,PRKAR2A |
| 2.605e-03 | -5.95 | translation | biological process | GO:0006412 | 375 | 68 | 16441 | 2138 |
EIF3C,RARS2,AARS2,MRPL10,RPS29,AARS,PABPC4,DENR,MRPS30,SRPRB,FARSA,RPS16,MRPS27,ETF1,YARS,NARS2,GARS,EIF4E3,NARS,HARS,EIF3J,MTIF2,MRRF,EIF3H,WARS,DDX3X,COPS5,EEFSEC,FTSJ1,EIF2B3,CARS,SARS,LARS2,AGO2,FARS2,VARS,SSR4,GFM2,YARS2,IGF2BP3,MRPS11,EIF2S2,GATC,SELT,HARS2,MRPL21,PPA1,PABPC1,RPL22L1,RPS6KB2,GTF2H3,WARS2,EIF4A2,MRPS10,MARS,EIF2A,GUF1,EIF5B,ABCF1,TARS,MRPL36,EPRS,RARS,RPL28,SRP68,EIF2S1,CDKAL1,SRP14 |
| 2.618e-03 | -5.95 | transforming growth factor beta receptor signaling pathway | biological process | GO:0007179 | 137 | 30 | 16441 | 2138 |
CGN,NCOR2,GCNT2,PXN,ID1,SMAD7,FERMT2,PTK2,MEN1,TGFB2,TGFBR2,UBC,SKI,SMAD3,SKIL,FKBP1A,SNW1,CCNT1,PMEPA1,UCHL5,CDK9,MYC,HIPK2,E2F4,RNF111,ADAM9,NCOR1,PARD3,USP15,PTPRK |
| 2.618e-03 | -5.95 | MILI_PSEUDOPODIA_CHEMOTAXIS_UP | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_UP | 70 | 18 | 17758 | 2279 |
PHLDB2,CENPB,DDR2,AKAP12,EIF2A,DKC1,PALLD,NBEAL1,INPP1,EIF2S2,RASSF3,ZBTB12,ANKRD11,GLTP,ANP32B,BMI1,SAMD4A,DCAF5 |
| 2.620e-03 | -5.94 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 2797 | 410 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,PRKCA,LPAR3,GABPB2,LPIN1,NOS1AP,SKI,TOM1L1,SREBF2,ZFHX3,PMAIP1,WIZ,RNF111,ZNF148,FNIP2,MEIS3,CDK6,DDN,HMBOX1,NRAS,NR6A1,GNL3,EYA3,NFIA,TCEB3,CUX1,C5AR1,SUPT20H,DCUN1D5,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,CCNT1,ARL6IP5,FIS1,DIRAS1,RUNX1,NRP1,BMI1,RFXAP,MEF2C,BANP,EPM2AIP1,IFT57,DROSHA,EGR1,JUP,SLK,KHDRBS1,SIRT7,PID1,RSF1,TGFBR2,PDCD5,CDC73,ABCA7,RBM20,FKBP1A,PRKCE,UBE3A,APLF,MYC,MED24,ANP32B,MAP3K12,LPCAT1,CAV2,PABPC1,TERF2,MYB,HMGCR,PEA15,GTF2H3,BDNF,SYNGAP1,WDR61,STAG1,RREB1,RB1CC1,PRDM16,ARID5B,RAP1B,SMARCD3,ARID1A,NELFA,ARRDC4,PLCB1,TRIM37,ONECUT2,ABCF1,ARIH2,IRS1,CAT,TASP1,KIDINS220,NSF,HIF1A,CDK9,SPEN,NCOR1,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,MYH9,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SLX4,SHC1,ACD,WAC,LPIN2,MMP14,DTNBP1,KMT2A,PERP,CASP8AP2,KMT2D,BRD4,DLG4,SATB2,MED16,MEF2D,SETD7,STK10,ERC1,SERP1,FGFR1,SNCA,VDR,TAF2,FBXL5,CAMK2D,CDC16,SMARCC1,NSMCE2,DNAJA3,PEMT,HIPK2,H2AFX,RPS6KB1,ANXA2,BRCC3,MID1,HMGA2,INSIG2,BRAF,TCF3,ID2,GAS6,TRIM22,TGFB2,RPS6KA5,FOXO3,PSMF1,MAD2L2,NEDD4,SFR1,TADA3,ABL1,SNW1,TRIAP1,RDX,YBX3,LARP4B,MAP3K14,SAMD4A,SOX6,SPTAN1,MBTPS2,SLC40A1,FGF9,PXN,APEX1,PTK2,IL6R,UBE2K,GUF1,KLF6,FOXC1,UBC,POLR2A,OXSR1,TRIB3,NSD1,ARID3B,APAF1,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,DDIT3,KAT6A,STK4,TRIM16,AAMDC,ATRX,NF1,KMT2E,GPBP1L1,PPARGC1B,PTPRA,RCHY1,CSNK2A1,SIRT2,HNRNPLL,BIRC2,MAP2K3,SMARCB1,ABL2,ANAPC1,RAP1A,PHF5A,DHX33,ANAPC11,ANAPC10,RELB,ZEB1,PCOLCE2,RAN,ETV1,TRIM14,PRKACB,SRPK2,ZBTB17,DEAF1,TNK2,TRIM13,RBCK1,ATF4,GCNT2,PPARG,ANK2,CDK4,ARRDC3,HSPA5,SUMO3,BRCA1,CAV1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,ZNF622,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,SOCS4,TNFRSF1A,ADAM9,CLU,DLX2,ZC3H8,UQCC2,MTCH1,FN1,FOXO1,TAF1,PAX2,NKD2,MAPK8IP3,SMAD7,LAMTOR3,BARX2,TRIM15,ZIC2,RLF,ARID1B,RHBDD1,NAMPT,RNF40,ELL,SUB1,CEP290,NDRG4,BUD31,GTF2H1,CTR9,VAPB,ICE2,WNT16,NRIP1,CAMKK2,CRADD,PAXBP1,UTP15,WWC1,PSMA1,PRDM1,EIF2A,SUPT5H,HERPUD1,UBE2E1,TCF7L2,NR2F1,ATXN7,SPAG9,IRAK2,ZFP90,TBL1X,PRKAR2A,TESC,TCF12,DLL4,ID1,ASH1L,CEMIP,SMARCA4,PBX1,RIPK1,PIBF1,PELP1,KDM1A,RRN3,NRF1,BRE,JAG1,CAMTA2,NVL,GRIN2C,IKBKB,MET,SPIDR,CASP10,HTRA2,CTC1,MAML3,PRPF19,MOSPD1,KAT8,DDX41,RAB7A,C1QTNF1,GRHL3,ATXN1,VIM,DKC1,EDEM2,ZC3H12A,SMAD3,IKZF4,ADNP,SIX5,COPS5,KLF4,CEBPZ,ARNTL,ATG7,DUSP19,PUS1,HEATR1,PKIB,DNAJC2,TNIK,MINK1,SUPT6H,MAP3K13,CAMK1,AGO2,ATF7IP,BMP6,PRKCH,TMEM161A,HAS3,CD44,UTS2,DMRT1,PKNOX1,RPS6KB2,KDM6B,ARNTL2,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,MEN1,SYMPK,PIK3CB,HSPA1B,MKX,RERE,GADD45A,TBX3,TAF4,CSRNP1,BCAS3,FNTB,NCBP2,MYRF,RBPJ,TAF12,NFKBIB,NR2F2,ZAK |
| 2.642e-03 | -5.94 | ORGANELLE_MEMBRANE | MSigDB lists | ORGANELLE_MEMBRANE | 295 | 55 | 17758 | 2279 |
MYO7A,PCSK7,RTN4,DPM3,OPA1,XPO7,TIMM10,NUP160,NDUFS7,DOPEY1,RTN1,NDUFV1,ATP5G2,NUP133,PMPCA,VAPB,CORO1A,NDUFA6,TOMM34,HTRA2,SLC25A1,TIMM50,HMGCR,MALL,TIMM8B,ABCC4,BCS1L,MCL1,RANGAP1,CAV1,KRTCAP2,NUP214,RHOT2,HERPUD1,ATP5D,PEX1,MFN2,TAMM41,RANBP2,RETSAT,KPNA1,SERINC1,KPNA3,TIMM17A,LEMD3,GLG1,SURF1,MPV17,LARGE,SLC25A11,PEX13,FIS1,DHCR7,AP2S1,KIF1B |
| 2.647e-03 | -5.93 | chronic_myelomonocytic_leukaemia | COSMIC cancer mutations | chronic_myelomonocytic_leukaemia | 151 | 32 | 17775 | 2278 |
ARHGAP26,HMGA2,BRAF,DDX18,NF1,ATRX,BCOR,ABL1,ATXN7L1,SH2B3,SRSF2,SOCS1,ABCA12,MYC,MET,KMT2A,SRPK2,SF3A1,NRAS,KMT2D,SKIV2L2,KDM5A,CUX1,KMT2C,PHF6,FGFR1,PRPF40B,NSD1,HIPK2,ATM,VPS13D,RUNX1 |
| 2.647e-03 | -5.93 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia | 151 | 32 | 17775 | 2278 |
ARHGAP26,HMGA2,BRAF,DDX18,NF1,ATRX,BCOR,ABL1,ATXN7L1,SH2B3,SRSF2,SOCS1,ABCA12,MYC,MET,KMT2A,SRPK2,SF3A1,NRAS,KMT2D,SKIV2L2,KDM5A,CUX1,KMT2C,PHF6,FGFR1,PRPF40B,NSD1,HIPK2,ATM,VPS13D,RUNX1 |
| 2.653e-03 | -5.93 | LEI_MYB_TARGETS | MSigDB lists | LEI_MYB_TARGETS | 308 | 57 | 17758 | 2279 |
FN1,TRIP6,JUP,DPF2,TRIO,APRT,BHLHE40,RAC3,STAM,SH2B3,DST,FARSA,NDUFV1,ASNS,IDI1,S100A10,PPID,MYC,VPS72,ME1,ANP32B,LPCAT1,VCL,ATP6V0D1,SERBP1,SLC25A1,PEA15,FADS1,COL17A1,KRT7,APEX1,TSTA3,CRIM1,CDK4,ARID5B,SEMA3F,VIM,MCL1,CAV1,MCM2,PALLD,TRIM37,ISG15,UBC,ATP5D,ANXA1,SMAD3,RARS,FGFBP1,E2F4,AHNAK2,RPS6KB1,CLU,TPM1,IFITM2,TMEM158,LAMA5 |
| 2.662e-03 | -5.93 | cellular response to oxidative stress | biological process | GO:0034599 | 173 | 36 | 16441 | 2138 |
FOXO1,PPARGC1B,PAX2,SIRT2,FOXO3,HSPA1A,ABL1,TMEM161A,WNT16,FXN,LONP1,HTRA2,PTPRK,KDM6B,ATF4,PXN,PDK1,KLF6,MTR,MGST1,PYCR1,HSPA1B,SNCA,ANXA1,ZNF622,HIF1A,KLF4,G6PD,ARL6IP5,ARNTL,MPV17,DPEP1,BMP4,TPM1,TXN2,MAPT |
| 2.666e-03 | -5.93 | PECE_MAMMARY_STEM_CELL_DN | MSigDB lists | PECE_MAMMARY_STEM_CELL_DN | 127 | 28 | 17758 | 2279 |
CHD9,SHQ1,AK2,ATRX,JMJD1C,TRIO,TPM4,ARHGAP32,UBE2K,UBR5,TCF7L2,SLC30A7,GNG2,DDX3X,CHN1,RGS17,IDI1,CDC16,JAG1,ZKSCAN1,VCAN,ZDHHC6,MMP14,SQLE,PURB,RABEP1,TROVE2,TNRC6A |
| 2.668e-03 | -5.93 | COPII vesicle coat | cellular component | GO:0030127 | 9 | 5 | 17570 | 2233 |
VMA21,SEC31A,SEC24A,SEC24D,SEC24C |
| 2.670e-03 | -5.93 | APRT (adenine phosphoribosyltransferase) | protein interactions | 353 | 27 | 10 | 16036 | 2270 |
HPRT1,CUL7,FN1,RAB7A,LDHA,APRT,UMPS,MLH1,PABPC4,LYPLA2 |
| 2.670e-03 | -5.93 | DDA1 (DET1 and DDB1 associated 1) | protein interactions | 79016 | 74 | 20 | 16036 | 2270 |
SRM,CUL4A,ADSL,TOR1AIP2,MCM2,TARS,UBE2E1,AMBRA1,MRPS11,WARS,NAMPT,PWP1,ASNS,COPS4,COPS3,COPS5,SHMT2,COPS7B,COPS6,DCAF5 |
| 2.676e-03 | -5.92 | neural tube development | biological process | GO:0021915 | 155 | 33 | 16441 | 2138 |
IFT57,CELSR1,LUZP1,NF1,PAX2,MKS1,ENAH,ZFP36L1,ZIC2,LIAS,PHGDH,RPGRIP1L,AMBRA1,SKI,ZNF358,PRKACB,MTHFD1,DEAF1,SETD2,FZD3,GRHL3,MTHFD1L,ARID1A,SOX4,TCTN1,TCF7L2,HIF1A,ARL13B,IFT140,SEMA3C,BMP4,APAF1,STK4 |
| 2.678e-03 | -5.92 | TOMLINS_PROSTATE_CANCER_DN | MSigDB lists | TOMLINS_PROSTATE_CANCER_DN | 39 | 12 | 17758 | 2279 |
LAMA4,DST,CYLD,ZNF516,PTRF,SVIL,AKAP12,PPP1R12B,CLU,ITGB4,VCL,LPIN1 |
| 2.680e-03 | -5.92 | FGL1 (fibrinogen like 1) | protein interactions | 2267 | 69 | 19 | 16036 | 2270 |
GTF2H3,FAM172A,TRIP6,TLE3,TFIP11,AARS2,MAP1S,RIPK1,TUBE1,SPATS2L,LSG1,PXDN,UBR1,ATXN2,PPIL2,GTF2H1,CWF19L2,BORCS5,NAA35 |
| 2.695e-03 | -5.92 | RNA Polymerase III Transcription Initiation From Type 3 Promoter | REACTOME pathways | R-HSA-76071 | 28 | 10 | 8202 | 1117 |
POLR3D,POLR3E,POU2F1,CRCP,POLR3B,POLR1C,SNAPC4,POLR3A,SNAPC5,POLR3G |
| 2.698e-03 | -5.92 | positive regulation of response to DNA damage stimulus | biological process | GO:2001022 | 64 | 17 | 16441 | 2138 |
HMGA2,SPRED2,MSX1,APEX1,NPAS2,EYA3,BRCA1,SKIL,BRE,PMAIP1,TMEM161A,MYC,NSMCE1,H2AFX,ATM,BRCC3,SPIDR |
| 2.705e-03 | -5.91 | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | MSigDB lists | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | 44 | 13 | 17758 | 2279 |
EGR1,COL5A2,LUC7L3,ATXN2,HSPA5,MYH9,FERMT2,NRP1,NR2F2,TPM1,VCL,KLF6,LPP |
| 2.705e-03 | -5.91 | MODULE_533 | MSigDB lists | MODULE_533 | 44 | 13 | 17758 | 2279 |
AOC3,DTNB,STX1A,CCNT1,KIF5A,BIVM,KIF5C,CORO1A,SNAP25,TRIM22,SEPT5,MID1,MAPT |
| 2.705e-03 | -5.91 | chr10q25 | MSigDB lists | chr10q25 | 44 | 13 | 17758 | 2279 |
ACSL5,BCCIP,RBM20,GSTO2,ITPRIP,SLK,PAX2,BBIP1,XPNPEP1,GPAM,SH3PXD2A,TCF7L2,SFR1 |
| 2.706e-03 | -5.91 | BROWNE_HCMV_INFECTION_14HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_UP | 151 | 32 | 17758 | 2279 |
UBN1,DBF4,RCHY1,KLHL18,PPP2R2A,SMG7,JMJD6,ISG20L2,ZNF44,PRKCA,SAFB2,CLINT1,SYNJ1,BMP6,USPL1,UPF2,POLE3,TOP1,GPM6A,ZBED4,MARCKSL1,PNN,HERPUD1,NEU1,TARS,TIMM44,DDX3X,BAZ1A,SLC39A14,ZNF266,LUC7L3,DLX2 |
| 2.706e-03 | -5.91 | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | MSigDB lists | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | 151 | 32 | 17758 | 2279 |
EP400,THOC5,DBF4,FANCD2,UBR5,GIT2,PAG1,NAMPT,IKBKB,RAN,SAP30,TMPO,GDAP1,PDE4A,ANK2,KIF15,WDHD1,BRCA1,NOP58,CENPP,CHAF1A,INF2,LSS,ATAD5,POLE2,SYNCRIP,STX1A,ZNF330,CSRNP1,SLCO5A1,BRD9,ZNF532 |
| 2.706e-03 | -5.91 | MORF_CDC2L5 | MSigDB lists | MORF_CDC2L5 | 139 | 30 | 17758 | 2279 |
SIK3,CHD9,EP400,MSX1,TTLL5,ATRX,PAFAH1B1,SFSWAP,SLC2A1,KIAA0586,KLHL18,TTI1,PIK3CB,PSMF1,RERE,HTR7,SEC31A,TAF2,RAP1A,SLC30A3,RBBP8,TP53BP1,TBC1D22A,CHD3,FNTB,SLC25A11,RUNX1,NFRKB,ARC,RPS6KB2 |
| 2.711e-03 | -5.91 | DNA-directed RNA polymerase II, holoenzyme | cellular component | GO:0016591 | 99 | 23 | 17570 | 2233 |
GTF2H3,WDR61,TAF1,MED18,CDC73,POLR2A,TAF9B,TAF2,TADA3,PAF1,TRRAP,GTF2A1,INTS7,TAF3,INTS5,TAF4,TBPL1,INTS9,GTF2H1,INTS12,CTR9,TAF12,CPSF3L |
| 2.722e-03 | -5.91 | bone-humerus-chondrosarcoma-central | COSMIC cancer mutations | bone-humerus-chondrosarcoma-central | 25 | 9 | 17775 | 2278 |
TMEM132B,HYAL3,ZFHX3,ASTN2,NAT10,LTN1,PCNXL2,MEN1,ABCA7 |
| 2.737e-03 | -5.90 | - | gene3d domains | 3.30.70.580 | 3 | 3 | 9988 | 1398 |
PUS1,PUS3,PUSL1 |
| 2.737e-03 | -5.90 | - | gene3d domains | 3.30.70.660 | 3 | 3 | 9988 | 1398 |
PUS3,PUS1,PUSL1 |
| 2.749e-03 | -5.90 | COVALENT_CHROMATIN_MODIFICATION | MSigDB lists | COVALENT_CHROMATIN_MODIFICATION | 25 | 9 | 17758 | 2279 |
KAT8,NSD1,SET,EHMT1,SIRT2,RPS6KA5,MAP3K12,CARM1,KAT6A |
| 2.749e-03 | -5.90 | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDM_DN | 194 | 39 | 17758 | 2279 |
BCCIP,FAM189B,STXBP6,VTA1,TMEM183A,APRT,TGFBR2,NUP160,LCLAT1,CMTM3,MBNL1,NPRL2,EIF2S2,MCM5,SELT,PRMT5,TMEM14C,HSD17B12,ACSL5,BRD4,RAB7A,TYW1,SLC35D1,EVI5,STK10,STOML2,IREB2,HSDL2,TRAP1,HNRNPR,DNAJA3,KLF4,LRRC40,ZBTB12,PURB,BPNT1,ECHDC1,BAG1,TMEM33 |
| 2.749e-03 | -5.90 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | 194 | 39 | 17758 | 2279 |
SPRED2,DNAJC2,BRAF,EIF3C,CHCHD10,PRKCA,LCLAT1,EEA1,SCAF8,NAMPT,PHC2,SOCS1,TIMELESS,SERPINH1,PCK2,PABPC1,PPA1,ANTXR2,DDX24,TCEB3,TOR1AIP2,SHISA5,ZNFX1,CCNDBP1,IL6R,ISG15,VPS53,MAT2A,POLR3A,GEMIN5,SMAD3,SKIL,PDLIM1,DNAJA3,SYNGR2,RABEP1,XPO6,IPO4,USP15 |
| 2.749e-03 | -5.90 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 194 | 39 | 17758 | 2279 |
TCF12,MCM6,ACTG1,TNFRSF21,CSNK2A1,SF3A3,RNASEH2B,RMI1,RPGRIP1L,DENR,PTPN2,ADH5,NUBPL,RNFT2,MCAM,USPL1,DNAJB6,DSG2,TIMELESS,UPF2,ETF1,GTF3C3,POLE3,PNMA1,TRIP13,CHD9,GARS,SIGMAR1,ELP3,RAP1GDS1,VIM,IMPDH2,FKBP3,PGD,UBAP2,BAZ2B,HNRNPR,PSAP,PTP4A2 |
| 2.753e-03 | -5.89 | Complex1_LYR | interpro domains | IPR008011 | 9 | 5 | 18293 | 2341 |
LYRM4,NDUFA6,LYRM5,LYRM2,LYRM7 |
| 2.756e-03 | -5.89 | cell cycle process | biological process | GO:0022402 | 1057 | 168 | 16441 | 2138 |
CUL7,CUL4A,KMT2E,PRKAB2,FANCD2,CSNK2A1,TUBE1,SIRT2,PRKCA,NUP160,BIRC2,LPIN1,SMARCB1,DST,ANAPC1,ZFHX3,NEK6,XRCC2,ANAPC11,ANAPC10,MAD1L1,PDS5B,RAN,CEP135,CDK6,SEH1L,TRIP13,CDK4,KIF15,HDAC8,BRCA1,MCM2,SOX4,SON,RHOU,SKIL,TCF7L1,TRRAP,BRCA2,TP53BP1,CHD3,E2F4,RAD51B,CCNB1IP1,CHMP4C,DCTN3,TTN,MCM6,KHDRBS1,SIRT7,LAMTOR3,PHGDH,SPIRE1,CEP164,CEP290,INTS7,MCM5,MYC,BANF1,TIMELESS,MYB,PEA15,STAG1,PRIM2,CRADD,ANAPC13,PPAT,POLA1,HAUS6,PSMA1,PLCB1,TCF7L2,UBE2E1,DYNC1H1,SDCCAG8,RRAGA,PPP1R12B,KIAA0196,NCOR1,BRSK2,SGSM3,SART1,CHMP2A,RAB11FIP4,PCNT,BIRC6,PAFAH1B1,ACTR3,HFM1,PPP2R2A,MYH9,SMARCA4,NUP43,PIBF1,SBDS,BRE,NUP133,WAC,ATRIP,MSH4,CEP63,PRPF19,RFC4,BRD4,RFC3,TUBA1A,STAMBP,ASUN,ARHGEF10,NUP214,TTC28,RAD54B,SMAD3,TAF2,RANBP2,RBBP8,CDC16,MISP,NSMCE2,H2AFX,RPS6KB1,BRCC3,SEPT5,NOLC1,HMGA2,ESCO1,KIZ,MCM10,XPC,DBF4,ID2,GAS6,CEP126,MLH1,TGFB2,CSNK1A1,PSMF1,POGZ,GIGYF2,MAD2L2,POM121,SFI1,TADA3,ABL1,TRIAP1,FBXO31,DIS3L2,NUDC,PPP1R9B,APEX1,FOXN3,SMARCAD1,TEX14,TOP3A,TBRG4,UBC,MFN2,RPA1,KLHL22,GADD45A,POLE2,ORC5,CUL2,MSH3,ATM,ZAK,ANAPC4,DDIT3 |
| 2.764e-03 | -5.89 | mitochondrial inner membrane | cellular component | GO:0005743 | 465 | 80 | 17570 | 2233 |
CYP24A1,IMMP2L,NDUFA5,LETM1,SUCLG1,NDUFAF2,PDK4,MRPL10,NDUFB5,SLC25A21,SLC25A44,SLC9B2,COX10,COA1,MRPS30,NDUFB3,ABCA12,ATP5G2,LETM2,MRPS27,NDUFA6,MTHFD2L,SLC25A23,MPST,TIMM50,ACSL5,SFXN4,CPOX,FOXRED1,MGST1,MPC1,ATP5D,STOML2,SNCA,TIMM44,TAMM41,TIMM17A,MPV17,SLC25A11,FAHD1,UQCC2,SLC25A26,MTCH1,HERC2,AK2,HSD17B10,SLC25A12,OPA1,TIMM10,NDUFS7,SLC25A20,MRPS11,NDUFV1,PMPCA,SHMT2,ALDH18A1,MRPL21,COQ3,SLC25A1,NIPSNAP1,BDNF,TIMM8B,TMEM126A,BCS1L,MRPS10,EXOG,CPT1A,GUF1,CHCHD6,C19orf70,MRPL36,ETFDH,TRAP1,COQ9,SURF1,SLC25A19,NDUFAF5,GPAM,NDUFS5,UQCC1 |
| 2.780e-03 | -5.89 | histone methyltransferase complex | cellular component | GO:0035097 | 71 | 18 | 17570 | 2233 |
KAT8,AEBP2,KMT2D,SETD1B,PRPF31,KMT2E,TAF1,KMT2C,MEN1,TRIM37,PELP1,MGA,KANSL1,TAF4,SENP3,RNF2,PRMT5,KMT2A |
| 2.794e-03 | -5.88 | RB1CC1 (RB1-inducible coiled-coil 1) | protein interactions | 9821 | 45 | 14 | 16036 | 2270 |
SKIL,EXOC1,TBKBP1,SESN2,YLPM1,PRKAB2,VAPB,RNF111,PTK2,SAFB2,UBC,RPA1,SKI,SMARCB1 |
| 2.794e-03 | -5.88 | QPRT (quinolinate phosphoribosyltransferase) | protein interactions | 23475 | 45 | 14 | 16036 | 2270 |
SRCAP,SUFU,ADNP,TLE3,PER1,VPS72,SF3A3,SATB2,NCOR1,BCOR,GIT2,ARID1B,SEH1L,SF3A1 |
| 2.801e-03 | -5.88 | THUMPD1 (THUMP domain containing 1) | protein interactions | 55623 | 19 | 8 | 16036 | 2270 |
OXSR1,SYNCRIP,HARS,NAT10,PPP2R2A,PUS1,ZC3H8,BAG1 |
| 2.801e-03 | -5.88 | HSP90AB2P (heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene) | protein interactions | 391634 | 19 | 8 | 16036 | 2270 |
TRIM16,COPS5,CUL2,CAMKMT,SHMT2,METTL22,TOMM34,TERF2 |
| 2.801e-03 | -5.88 | TLE4 (transducin-like enhancer of split 4) | protein interactions | 7091 | 19 | 8 | 16036 | 2270 |
MSX1,CUX1,TSSC1,LIG4,POU2F1,BRCA1,PRMT5,SRPK2 |
| 2.804e-03 | -5.88 | TCTGATA,MIR-361 | MSigDB lists | TCTGATA,MIR-361 | 87 | 21 | 17758 | 2279 |
AEBP2,GPHN,ACTG1,CPOX,USP42,PDE4B,NHS,MED13L,UBE2K,SON,UBR5,SCAF8,ZNF655,RPA1,DDX3X,CAMK2D,LRP1B,LUC7L3,PRICKLE2,MAGI1,LARP4B |
| 2.806e-03 | -5.88 | PWP2 (PWP2 periodic tryptophan protein homolog (yeast)) | protein interactions | 5822 | 23 | 9 | 16036 | 2270 |
WDR36,MPHOSPH10,CUL7,DDX18,SIRT7,RNF2,FBL,USP36,TOM1L1 |
| 2.806e-03 | -5.88 | ZEB1 (zinc finger E-box binding homeobox 1) | protein interactions | 6935 | 23 | 9 | 16036 | 2270 |
SMAD3,USP7,GTF2A1,SMAD7,ATM,SMARCA4,SERPINH1,UBR4,CDK6 |
| 2.824e-03 | -5.87 | negative regulation of cellular protein catabolic process | biological process | GO:1903363 | 75 | 19 | 16441 | 2138 |
UBXN1,OPHN1,TEX14,CSNK2A1,PSMF1,MAD2L2,UBE2E1,KLHL22,ANAPC1,CDC16,SMARCC1,WAC,ANAPC11,ANAPC10,MAD1L1,ATM,ANXA2,FHIT,ANAPC4 |
| 2.832e-03 | -5.87 | postreplication repair | biological process | GO:0006301 | 59 | 16 | 16441 | 2138 |
RFC4,RFC3,CUL4A,POLK,RCHY1,USP10,HLTF,BRCA1,MAD2L2,ISG15,UBC,RPA1,POLE2,RAD18,NSMCE1,WDR33 |
| 2.833e-03 | -5.87 | GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13) | protein interactions | 114805 | 3 | 3 | 16036 | 2270 |
SKIV2L,EXOSC2,COPS5 |
| 2.833e-03 | -5.87 | CLVS2 (clavesin 2) | protein interactions | 134829 | 3 | 3 | 16036 | 2270 |
SNU13,DDX41,APEX1 |
| 2.833e-03 | -5.87 | ZCCHC9 (zinc finger, CCHC domain containing 9) | protein interactions | 84240 | 3 | 3 | 16036 | 2270 |
NIFK,SURF2,ZC3H3 |
| 2.833e-03 | -5.87 | Rmdn3 (regulator of microtubule dynamics 3) | protein interactions | 67809 | 3 | 3 | 16036 | 2270 |
VAPB,RMDN3,SNCA |
| 2.833e-03 | -5.87 | C4orf33 (chromosome 4 open reading frame 33) | protein interactions | 132321 | 3 | 3 | 16036 | 2270 |
DCXR,TRIP13,VAC14 |
| 2.833e-03 | -5.87 | ESRP1 (epithelial splicing regulatory protein 1) | protein interactions | 54845 | 3 | 3 | 16036 | 2270 |
ATXN1,RNF2,BMI1 |
| 2.833e-03 | -5.87 | SNX25 (sorting nexin 25) | protein interactions | 83891 | 3 | 3 | 16036 | 2270 |
VAPB,SIX5,TSPAN5 |
| 2.833e-03 | -5.87 | DCAF4L1 (DDB1 and CUL4 associated factor 4-like 1) | protein interactions | 285429 | 3 | 3 | 16036 | 2270 |
CUL4A,COPS6,COPS5 |
| 2.838e-03 | -5.86 | marginal_zone_lymphoma | COSMIC cancer mutations | marginal_zone_lymphoma | 342 | 62 | 17775 | 2278 |
ARHGAP26,AMOTL1,BRAF,CYLD,ACTG1,XPC,KIF5A,DPF2,FANCD2,MAPK8IP3,TRPM6,CACNA1H,ZNF107,ARID1B,DDX60L,YLPM1,HAS3,GLYR1,IKBKB,WAC,RAPGEFL1,KIAA0922,MTHFD2L,PRKACB,MAML3,PTPRK,KLRD1,ACSL5,TSHZ1,FLNC,DDX28,DTNB,EIF4E3,NRAS,KMT2D,STAG1,RREB1,FZD3,GRHL3,TBRG4,OBSCN,PHACTR2,ZNFX1,ARID1A,TRIM37,SLC9A5,CRYBG3,SYMPK,LSG1,KIF16B,CDH24,LRP1B,TRRAP,ELP2,SERINC1,SPEN,FAT1,CSMD3,ABCC3,TRAF3,DISP1,PTPN14 |
| 2.850e-03 | -5.86 | ER-nucleus signaling pathway | biological process | GO:0006984 | 34 | 11 | 16441 | 2138 |
INSIG2,ASNS,ATF4,INSIG1,HSPA5,EIF2S1,CCDC47,EIF2A,HERPUD1,DDIT3,MBTPS2 |
| 2.850e-03 | -5.86 | regulation of ubiquitin protein ligase activity | biological process | GO:1904666 | 34 | 11 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 2.850e-03 | -5.86 | spindle assembly checkpoint | biological process | GO:0071173 | 34 | 11 | 16441 | 2138 |
KLHL22,ANAPC1,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,ATM,MAD2L2,UBE2E1,ANAPC4 |
| 2.853e-03 | -5.86 | SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5) | protein interactions | 8467 | 95 | 24 | 16036 | 2270 |
CUL7,BAZ2A,POLR1A,SMARCAD1,BRCA1,RSF1,PHGDH,HIST2H2AB,POLR3A,RPA1,BAZ1A,UBTF,MYBBP1A,SMARCC1,HNRNPR,CHD3,MYC,COPS3,RNF2,POLE3,POLR3B,POLR1C,BMI1,HNRNPM |
| 2.883e-03 | -5.85 | DNA-dependent DNA replication | biological process | GO:0006261 | 103 | 24 | 16441 | 2138 |
POLB,RFC4,MCM6,MCM10,RFC3,GINS3,PRIM2,APEX1,ATRX,POLA1,C10orf2,LIG4,MCM2,POLG2,RPAIN,ZRANB3,RPA1,BAZ1A,BRCA2,POLE2,MCM5,CDK9,DNAJA3,ORC5 |
| 2.887e-03 | -5.85 | PDEASE_I | prosite domains | PS00126 | 21 | 8 | 11866 | 1504 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 2.892e-03 | -5.85 | V$USF_02 | MSigDB lists | V$USF_02 | 264 | 50 | 17758 | 2279 |
TCF12,UTP14A,ATP6V1A,UROD,NFX1,ATF7IP,TGFB2,RLF,UBR5,BMP6,DHX35,GIGYF2,IQGAP2,RSPRY1,FAM192A,MCAM,STC2,DCTN4,GTF2H1,IGF2BP1,KIAA0922,ETV1,PRPS1,PABPC1,NUDC,MTHFD1,BDNF,ATF4,SIGMAR1,SETD2,TOP3A,AKAP12,CPT1A,NOP58,MAT2A,SLC23A2,BATF3,DDX3X,TOM1L2,GTF2A1,KIAA0355,PER1,LUC7L3,UMPS,MBD6,EME1,RUNX1,PFDN2,DDIT3,NIT1 |
| 2.900e-03 | -5.84 | SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1) | protein interactions | 6599 | 111 | 27 | 16036 | 2270 |
DPF3,ARID2,SMARCAD1,DPF2,SIRT7,SMARCD3,SMARCA4,BRCA1,ARID1A,ARID1B,KDM1A,NEDD4,SMARCB1,SMAD3,CHD7,SMARCC1,YLPM1,MYC,RELB,RNF2,NCOR1,RUNX1,PRMT5,BMI1,SRRM2,CARM1,SF3A1 |
| 2.901e-03 | -5.84 | cell cycle | biological process | GO:0007049 | 1319 | 205 | 16441 | 2138 |
PTP4A1,CUL7,CUL4A,KMT2E,PRKAB2,FANCD2,CSNK2A1,TUBE1,SIRT2,PRKCA,NUP160,BIRC2,LPIN1,SMARCB1,DST,ANAPC1,ZFHX3,NEK6,XRCC2,ANAPC11,ANAPC10,MAD1L1,PDS5B,RAN,CEP135,CDK6,SEH1L,TRIP13,TXLNG,CDK4,KIF15,HDAC8,BRCA1,MCM2,SOX4,SON,CHAF1A,GNAI1,RHOU,SKIL,TCF7L1,TRRAP,BRCA2,TP53BP1,CHD3,CCNT1,E2F4,RAD51B,CCNB1IP1,DMTF1,CHMP4C,BANP,DCTN3,TTN,MCM6,TAF1,KHDRBS1,SIRT7,LAMTOR3,PHGDH,CDC73,SPIRE1,PRKCE,CEP164,CEP290,INTS7,MCM5,MYC,BANF1,TIMELESS,CCDC124,TERF2,MYB,PEA15,STAG1,PRIM2,CRADD,ANAPC13,PPAT,RB1CC1,POLA1,HAUS6,PSMA1,LIG4,SUPT5H,EVI5,PLCB1,TCF7L2,UBE2E1,DYNC1H1,SDCCAG8,RRAGA,PPP1R12B,KIAA0196,NCOR1,BRSK2,SGSM3,BCCIP,SART1,CHMP2A,CYLD,RAB11FIP4,PCNT,BIRC6,PAFAH1B1,HFM1,ACTR3,PPP2R2A,SMARCA4,MYH9,NUP43,PIBF1,SBDS,KCTD11,BRE,NUP133,WAC,ATRIP,RNF2,MSH4,CEP63,CASP8AP2,PRPF19,RFC4,RFC3,BRD4,TUBA1A,STAMBP,TEX19,ASUN,ARHGEF10,CCNDBP1,TTC28,NUP214,STK10,RAD54B,SMAD3,TAF2,EXO1,RANBP2,CDC16,RBBP8,MISP,NSMCE2,H2AFX,RPS6KB1,SEPT5,BRCC3,NOLC1,PARD3,HMGA2,ESCO1,MCM10,KIZ,XPC,CAMK1,DBF4,ID2,GAS6,PPP1R1C,MLH1,CEP126,TGFB2,CSNK1A1,PSMF1,POGZ,GIGYF2,MAD2L2,POM121,SFI1,TADA3,ABL1,SUV39H2,TRIAP1,FBXO31,NUDC,DIS3L2,PPP1R9B,TRNP1,GINS3,APEX1,FOXN3,SMARCAD1,PSMC3IP,TEX14,TOP3A,TBRG4,RANGAP1,HIST1H4J,MEN1,UBC,CENPP,MFN2,RPA1,KLHL22,POLE2,GADD45A,CUL2,ORC5,SET,MSH3,ATM,ZAK,ANAPC4,DDIT3 |
| 2.940e-03 | -5.83 | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | 60 | 16 | 17775 | 2278 |
BRAF,NRAS,NF1,MLH1,BRCA1,KMT2C,MEN1,FGFR1,SMARCB1,ABL1,BRCA2,SUFU,ATM,RUNX1,MET,MAP2K4 |
| 2.946e-03 | -5.83 | transcriptionally active chromatin | cellular component | GO:0035327 | 21 | 8 | 17570 | 2233 |
ELL,WDR61,BCAS3,CTR9,ICE2,EXOSC4,ZC3H8,PELP1 |
| 2.951e-03 | -5.83 | DE_YY1_TARGETS_DN | MSigDB lists | DE_YY1_TARGETS_DN | 93 | 22 | 17758 | 2279 |
PTP4A1,IFT57,CYLD,FN1,STAG1,PAFAH1B1,PNN,ENC1,TGFB2,ANXA1,DST,RGS17,PRKD3,RBBP8,HIF1A,RASSF3,HIPK2,NCOR1,MET,NRP1,PRKACB,CASP8AP2 |
| 2.960e-03 | -5.82 | regulation of RNA export from nucleus | biological process | GO:0046831 | 9 | 5 | 16441 | 2138 |
NCBP2,SUPT6H,ZC3H3,KHDRBS1,SETD2 |
| 2.960e-03 | -5.82 | tRNA wobble base modification | biological process | GO:0002097 | 9 | 5 | 16441 | 2138 |
CTU2,ADAT2,TRMU,ELP3,ALKBH8 |
| 2.960e-03 | -5.82 | regulation of histone ubiquitination | biological process | GO:0033182 | 9 | 5 | 16441 | 2138 |
RNF40,CTR9,CDK9,UBR5,KDM1A |
| 2.960e-03 | -5.82 | desmosome organization | biological process | GO:0002934 | 9 | 5 | 16441 | 2138 |
JUP,PRKCA,DSP,DSG2,PERP |
| 2.960e-03 | -5.82 | cullin deneddylation | biological process | GO:0010388 | 9 | 5 | 16441 | 2138 |
COPS7B,COPS6,COPS4,COPS3,COPS5 |
| 2.971e-03 | -5.82 | BROWN_MYELOID_CELL_DEVELOPMENT_DN | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_DN | 122 | 27 | 17758 | 2279 |
MSI2,FBXW4,APEX1,PSAT1,NARS,ST6GAL1,CDK4,SOX4,TRIM37,ODC1,NOP58,BZW2,NOP56,GART,TASP1,SMARCC1,IKZF4,NOP16,STC2,SLC16A1,SHMT2,POLR1B,NRIP1,NOLC1,LAMA5,CSGALNACT2,MYB |
| 2.978e-03 | -5.82 | DDX27 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 27) | protein interactions | 55661 | 50 | 15 | 16036 | 2270 |
PES1,NIFK,CUL7,DDX24,UTP14A,SRP68,SIRT7,RNF2,FBL,DKC1,RBM19,NOP58,FTSJ3,PUM3,NOP56 |
| 2.978e-03 | -5.82 | SEC24A (SEC24 homolog A, COPII coat complex component) | protein interactions | 10802 | 50 | 15 | 16036 | 2270 |
SEPHS2,TTC1,THADA,SEC24D,TLE3,SEC24C,PCMT1,JMJD6,TUBB6,AHCYL1,IGBP1,C18orf25,KIF1B,TRIP13,CLNS1A |
| 2.988e-03 | -5.81 | human chr12q24.11 | chromosome location | human chr12q24.11 | 32 | 9 | 26250 | 2590 |
FAM216A,ANKRD13A,HVCN1,FAM222A-AS1,C12orf76,GLTP,TCTN1,LINC01405,ARPC3 |
| 3.008e-03 | -5.81 | central_nervous_system-brainstem-glioma | COSMIC cancer mutations | central_nervous_system-brainstem-glioma | 356 | 64 | 17775 | 2278 |
ATRX,CACNA1H,BCOR,GIT2,PDE3A,CHD7,NRF1,TMEM184A,KDM2A,TBC1D22A,SNTG2,TTC3,FHIT,MET,CEP128,FLNC,NRAS,THSD4,KIF15,PCNXL2,SATB2,ERC1,FGFR1,IKZF4,HIPK2,CSMD3,MDN1,SPOCK3,DROSHA,MEX3A,FARS2,ATF7IP,MON2,DNAH1,CDC73,RMI1,IL17RE,RGS17,TAF3,ABCA5,GMDS,LPCAT1,SOX6,TMC7,ADAMTSL3,PRDM16,NXN,SNAP25,MTR,DDX49,CHCHD6,NAALADL2,DNAH14,LRP1B,SYNCRIP,ALKBH3,SRBD1,EXOC4,TMEM117,ATM,PEX13,ADK,KIF1B,ARHGAP27 |
| 3.009e-03 | -5.81 | regulation of RNA splicing | biological process | GO:0043484 | 92 | 22 | 16441 | 2138 |
PTBP2,CLK1,RBFOX2,SFSWAP,JMJD6,SON,MBNL2,HSPA1A,MBNL1,HNRNPLL,POLR2A,RBM20,SNW1,SRSF2,AHNAK,NSRP1,PQBP1,CELF1,CDK12,CLK2,PRPF19,SRPK2 |
| 3.011e-03 | -5.81 | human chr12q24.31 | chromosome location | human chr12q24.31 | 70 | 15 | 26250 | 2590 |
TMEM132B,ACADS,GTF2H3,PXN,GATC,DHX37,SETD1B,ZCCHC8,VPS37B,TRIAP1,SCARB1,POP5,WDR66,TMEM120B,DENR |
| 3.011e-03 | -5.81 | isoprenoid biosynthetic process | biological process | GO:0008299 | 25 | 9 | 16441 | 2138 |
IDI1,MVK,ISPD,FDPS,RDH10,PDSS2,RBP1,HMGCR,FDFT1 |
| 3.011e-03 | -5.81 | regulation of activin receptor signaling pathway | biological process | GO:0032925 | 25 | 9 | 16441 | 2138 |
FKBP1A,FGF9,LEMD3,SMAD7,ZIC2,MEN1,DMRT1,ZC3H3,SKI |
| 3.015e-03 | -5.80 | ATGTTTC,MIR-494 | MSigDB lists | ATGTTTC,MIR-494 | 152 | 32 | 17758 | 2279 |
CUL4A,CLK1,ATRX,ADAMTS6,ZIC2,BHLHE40,IKBKAP,SIPA1L3,NBEA,PRICKLE2,IGF2BP1,CDK12,DBN1,CHD9,ADAMTSL3,RB1CC1,SFSWAP,PPP1R21,RAP1B,PTPN12,ARHGEF12,SON,UBE2K,NAALADL2,YTHDF2,ZRANB3,DCBLD2,CAMK2D,LRP1B,LUC7L3,ARNTL,PURB |
| 3.021e-03 | -5.80 | RESPONSE_TO_ENDOGENOUS_STIMULUS | MSigDB lists | RESPONSE_TO_ENDOGENOUS_STIMULUS | 195 | 39 | 17758 | 2279 |
XPC,ATRX,MLH1,PDCD7,UBR5,RPAIN,ABL1,BRE,TRIAP1,XRCC2,GTF2H1,ATRIP,ME1,OGG1,PMS1,RFC3,APEX1,FOXN3,POLA1,LIG4,APTX,BRCA1,RAD54B,RPA1,EXO1,BRCA2,RBBP8,GADD45A,POLE2,RAD51B,MSH3,ATM,ALKBH1,EIF2B3,BRCC3,XRCC4,ZAK,MUTYH,DDIT3 |
| 3.021e-03 | -5.80 | GSE3982_NEUTROPHIL_VS_TH2_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH2_UP | 195 | 39 | 17758 | 2279 |
ZNF516,SH2D3A,CLK1,PSTPIP2,ACTR3,MAPK8IP3,MAP1S,ZFP36L1,NECAP1,WDR26,SYNJ1,GIT2,ECM1,NOVA2,VCL,CDK12,ULBP1,RBCK1,FOXN3,KDM5A,JMJD1C,POU2F1,ABCC2,R3HDM2,SERP1,ARPC3,BAZ2B,SLC30A3,SPAG9,ARID3B,ZZEF1,ARL4A,ACOX1,KLF4,CFD,VPS37B,RIOK3,APAF1,TBL1X |
| 3.024e-03 | -5.80 | negative regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903051 | 70 | 18 | 16441 | 2138 |
UBXN1,OPHN1,TEX14,CSNK2A1,PSMF1,MAD2L2,UBE2E1,KLHL22,ANAPC1,CDC16,SMARCC1,WAC,ANAPC11,ANAPC10,MAD1L1,ATM,FHIT,ANAPC4 |
| 3.026e-03 | -5.80 | pancreatic_intraepithelial_neoplasia_(PanIN) | COSMIC cancer mutations | pancreatic_intraepithelial_neoplasia_(PanIN) | 702 | 115 | 17775 | 2278 |
ZNF292,USP7,ABCA3,CYLD,PRKCSH,TFIP11,OSBPL9,AARS2,RSL1D1,RNF43,TUBB6,SEC16A,SYNJ1,PPP1R9A,DHX35,VPS18,EXOC1,MPHOSPH10,FAAH2,MRPS27,ZEB1,TTC3,POLR3B,CEP135,TSPAN14,LYST,CTC1,MAML3,VPS13B,KDM3B,DSC3,ABCC4,RFX2,TMEM123,KMT2C,POLG2,UBR4,HTR7,ARMC4,LSS,SH3RF1,CEBPZ,TMEM139,SLC4A7,ABCC3,GREB1L,PDCD11,DMTF1,YEATS2,CATSPERG,TRIM36,HERC2,FN1,FAM189B,RFX1,DYM,VPS45,FAN1,NFX1,TRIM15,LIAS,GIGYF2,MFHAS1,ZNF594,ASAP1,APLF,ZNF326,PRICKLE2,SHMT2,SELT,SYNJ2,NOC3L,CNOT4,POLR1E,PABPC1,N4BP2,HNRNPM,NAV3,MTHFD1,STAG1,SYNGAP1,LRRIQ1,WDFY3,KCNMA1,RYR2,WWC1,TTYH2,OBSCN,EIF2A,ARHGAP32,PPIP5K2,ANKRD20A4,SRA1,EHBP1,ARMC3,DNAH14,TCF7L2,POLR3G,IRS1,ZNF708,CDH24,NSD1,ASCC3,PXDN,C20orf196,NOL10,SRP68,DNAH17,CUL2,ATM,RBM26,NCOR1,IGBP1,XPO6,LRRC41 |
| 3.026e-03 | -5.80 | pancreas-pancreatic_intraepithelial_neoplasia_(PanIN) | COSMIC cancer mutations | pancreas-pancreatic_intraepithelial_neoplasia_(PanIN) | 702 | 115 | 17775 | 2278 |
ZNF292,USP7,ABCA3,CYLD,PRKCSH,TFIP11,OSBPL9,AARS2,RSL1D1,RNF43,TUBB6,SEC16A,SYNJ1,PPP1R9A,DHX35,VPS18,EXOC1,MPHOSPH10,FAAH2,MRPS27,ZEB1,TTC3,POLR3B,CEP135,TSPAN14,LYST,CTC1,MAML3,VPS13B,KDM3B,DSC3,ABCC4,RFX2,TMEM123,KMT2C,POLG2,UBR4,HTR7,ARMC4,LSS,SH3RF1,CEBPZ,TMEM139,SLC4A7,ABCC3,GREB1L,PDCD11,DMTF1,YEATS2,CATSPERG,TRIM36,HERC2,FN1,FAM189B,RFX1,DYM,VPS45,FAN1,NFX1,TRIM15,LIAS,GIGYF2,MFHAS1,ZNF594,ASAP1,APLF,ZNF326,PRICKLE2,SHMT2,SELT,SYNJ2,NOC3L,CNOT4,POLR1E,PABPC1,N4BP2,HNRNPM,NAV3,MTHFD1,STAG1,SYNGAP1,LRRIQ1,WDFY3,KCNMA1,RYR2,WWC1,TTYH2,OBSCN,EIF2A,ARHGAP32,PPIP5K2,ANKRD20A4,SRA1,EHBP1,ARMC3,DNAH14,TCF7L2,POLR3G,IRS1,ZNF708,CDH24,NSD1,ASCC3,PXDN,C20orf196,NOL10,SRP68,DNAH17,CUL2,ATM,RBM26,NCOR1,IGBP1,XPO6,LRRC41 |
| 3.058e-03 | -5.79 | organic substance catabolic process | biological process | GO:1901575 | 1534 | 235 | 16441 | 2138 |
GGT1,CYP24A1,CUL7,CUL4A,PRDX6,DCP1B,SLC25A21,HECTD3,RCHY1,RNF43,SIRT2,GYG1,NT5C3A,HMOX2,ABHD6,SYNJ1,BIRC2,UBR5,LPIN1,PABPC4,EDC3,TOM1L1,PCYOX1L,ANAPC1,AMPD3,RPS16,PMAIP1,PHKA1,ANAPC11,ANAPC10,HYAL1,RNF111,OGG1,PPM1K,LONP1,PRKACB,MPST,ACADS,TRIM13,RBCK1,SESN2,FBXW4,SKIV2L2,ITPA,UPP1,ALDH1L2,HSPA5,GPCPD1,TCEB3,DLST,PLCXD2,SPOP,KIF16B,GLS,HPRT1,DDAH2,BDH2,XPNPEP1,NOCT,USP15,CHMP4C,XYLB,FBXO45,LDAH,DROSHA,UBXN1,PIK3R4,HSD17B10,TATDN3,SMG7,ZFP36L1,PLA2G12A,CCDC47,PARN,RHBDD1,ETFB,RNF40,UBE3A,COPS3,PDE10A,PNPLA3,CNOT4,LRSAM1,AGL,PABPC1,NT5E,HSD17B14,USE1,EXOSC2,WDR61,PDE4A,PPAT,USP49,PCCA,EIF4A2,RNH1,USP10,PSMA1,PLCB1,CPT1A,ACOXL,USP46,HERPUD1,ISG15,ARIH2,UBE2E1,IRS1,CAT,DAGLA,POP1,KPNA1,RPL28,UBAP1,VCAN,HK2,ZCCHC6,DTD1,PEX13,CNOT6,TBL1X,BRSK2,C18orf25,PDE9A,AGO3,CPT1C,GALE,USP7,SDSL,CYLD,TRERF1,PAPD4,LIN28B,PAFAH1B1,CEMIP,RPS29,NTSR1,PPP2R2A,RIPK1,RNF24,DENND3,TNKS1BP1,PDE3A,DECR1,LYPLAL1,ERI1,UBR1,UCHL5,LPIN2,SOCS6,TTC3,ETF1,NT5C,HIBCH,PNPLA4,MGLL,HTRA2,AUP1,TMLHE,PRPF19,MCEE,SKIV2L,RAB7A,MARCH6,ENC1,EDEM2,NUDT15,UBR4,USP36,PDE8B,FBXL5,CDC16,HYAL3,DCXR,ARNTL,ATG7,USP11,MUTYH,SMG1,DMGDH,BCKDK,AUH,HM13,PDE4B,TKFC,MLH1,RNASEH2B,INPP1,PSMF1,NEDD4,DCTPP1,ADH5,PEX7,PHYKPL,UPF2,NLGN3,EXOSC4,FBXO31,CD44,ERI3,NT5M,FBXL19,LYPLA2,DIS3L2,PFKFB4,DDHD1,VPS37A,FGF2,USP42,DHX34,LDHA,PDE2A,EXOG,UBE2K,PDE3B,MMAA,NAPEPLD,NEU1,SMPDL3B,UBC,ECH1,CTIF,ETFDH,FBXO21,DAGLB,GPC2,ACOX1,SRD5A3,CUL2,USP20,ATM,NCBP2,TATDN1,ANAPC4,DDIT3,GCSH |
| 3.062e-03 | -5.79 | bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 396 | 70 | 17775 | 2278 |
USP7,ABCA3,C16orf45,SBF2,STK33,RADIL,AARS,JAG1,CAMTA2,NAA35,DBN1,TNK2,KMT2D,SKAP2,ABCC4,LIMA1,EHMT1,MARCKSL1,GNL1,SERGEF,DHX57,OSBPL1A,BAZ1A,CC2D1B,ARL13B,ZNF436,TRMT2A,ABCC3,MDN1,NFRKB,ANKS1A,LAMA5,CEP170,UNC13D,BRAF,FN1,LARS2,PDE4B,EVPL,BZW2,SCAF1,NDRG4,GREB1,POLR1B,FBXL19,LPCAT1,ZNF675,TMC7,ZNF234,BDNF,KCNQ3,PDE4A,ADAMTSL3,EPS15L1,OBSCN,PDE3B,AGAP1,SMPDL3B,MFN2,EXOC6,KIDINS220,WDR35,LEMD3,FAT1,SPEN,MSH3,ATM,PGAM5,SORCS2,DDX10 |
| 3.069e-03 | -5.79 | RNA transport | KEGG pathways | ko03013 | 166 | 34 | 6908 | 881 |
THOC5,EIF3C,POP5,NUP43,PABPC1L,NUP160,POM121,PABPC4,RPP30,EIF2S2,NUP133,UPF2,RAN,GEMIN4,PRMT5,PABPC1,SEH1L,EIF3J,XPO5,EIF4A2,SUMO3,RANGAP1,PNN,EIF5B,NUP214,EIF3H,CLNS1A,GEMIN5,POP1,RANBP2,EIF2S1,NCBP2,EIF2B3,NMD3 |
| 3.069e-03 | -5.79 | RNA transport | KEGG pathways | hsa03013 | 166 | 34 | 6908 | 881 |
THOC5,EIF3C,POP5,NUP43,PABPC1L,NUP160,POM121,PABPC4,RPP30,EIF2S2,NUP133,UPF2,RAN,GEMIN4,PRMT5,PABPC1,SEH1L,EIF3J,XPO5,EIF4A2,SUMO3,RANGAP1,PNN,EIF5B,NUP214,EIF3H,CLNS1A,GEMIN5,POP1,RANBP2,EIF2S1,NCBP2,EIF2B3,NMD3 |
| 3.070e-03 | -5.79 | nucleoside metabolic process | biological process | GO:0009116 | 319 | 59 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,MRI1,NDUFB5,OLA1,APRT,CHCHD10,NT5C3A,COX10,HSPA1A,NDUFS7,AHCYL2,NDUFB3,CAD,AMPD3,NDUFV1,ENTPD5,ATP5G2,ATIC,PPCDC,MYH3,NT5C,CMPK1,NDUFA6,AHCYL1,FXN,NT5M,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,PPAT,UPP1,SULT4A1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,MAT2A,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,NME7,PEMT,COQ9,HK2,SURF1,UMPS,NDUFS5,BPNT1,MACROD1,ADK |
| 3.080e-03 | -5.78 | PDEase_catalytic_dom | interpro domains | IPR002073 | 21 | 8 | 18293 | 2341 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 3.080e-03 | -5.78 | PDEase_CS | interpro domains | IPR023174 | 21 | 8 | 18293 | 2341 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 3.080e-03 | -5.78 | HATPase_C | interpro domains | IPR003594 | 21 | 8 | 18293 | 2341 |
BCKDK,PMS1,SACS,PDK1,TRAP1,PDK4,MLH1,MORC2 |
| 3.082e-03 | -5.78 | GSE3982_MAC_VS_TH1_DN | MSigDB lists | GSE3982_MAC_VS_TH1_DN | 189 | 38 | 17758 | 2279 |
ASH1L,FAM189B,KIF5C,BCOR,BHLHE40,PITPNM1,NPRL2,POLR3D,PMAIP1,XRCC2,HIRIP3,TIMELESS,KIAA0922,ALDH18A1,NAA35,PERP,ZBTB17,ARNTL2,RBCK1,TSTA3,NR6A1,IDH3G,AKAP12,CAV1,EIF5B,RHOT2,USP36,SMAD3,LMBR1L,GTF2A1,DNAJA3,PQBP1,PRPF4,PPP3CC,MED20,HMBS,NFKBIB,EIF2B3 |
| 3.084e-03 | -5.78 | RNA polymerase I regulatory region DNA binding | molecular function | GO:0001013 | 9 | 5 | 16491 | 2164 |
SMARCA4,UBTF,RRN3,BAZ2A,SMARCB1 |
| 3.084e-03 | -5.78 | protein binding involved in heterotypic cell-cell adhesion | molecular function | GO:0086080 | 9 | 5 | 16491 | 2164 |
NFASC,DSC2,JUP,DSP,DSG2 |
| 3.084e-03 | -5.78 | HDc | smart domains | SM00471 | 24 | 9 | 9131 | 1249 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,HDDC2,PDE8B |
| 3.093e-03 | -5.78 | purine NTP-dependent helicase activity | molecular function | GO:0070035 | 97 | 23 | 16491 | 2164 |
SKIV2L,DDX28,MCM6,DDX41,DDX24,DDX18,DDX19A,EIF4A2,DHX34,CHD5,DDX49,DHX35,DHX57,DDX3X,ASCC3,DDX56,DDX50,DHX37,CHD3,DHX33,DDX31,CHD2,DDX10 |
| 3.093e-03 | -5.78 | ATP-dependent helicase activity | molecular function | GO:0008026 | 97 | 23 | 16491 | 2164 |
SKIV2L,DDX28,MCM6,DDX41,DDX24,DDX18,DDX19A,EIF4A2,DHX34,CHD5,DDX49,DHX35,DHX57,DDX3X,ASCC3,DDX56,DDX50,DHX37,CHD3,DHX33,DDX31,CHD2,DDX10 |
| 3.095e-03 | -5.78 | SESTO_RESPONSE_TO_UV_C8 | MSigDB lists | SESTO_RESPONSE_TO_UV_C8 | 71 | 18 | 17758 | 2279 |
COL17A1,COL5A2,PRDX6,SLC2A1,R3HDM1,REEP5,FLNB,DST,EPRS,MTHFD2,MYC,GLG1,MRPS27,ME1,TTC3,SEMA3C,PTPRK,FDFT1 |
| 3.097e-03 | -5.78 | purine ribonucleoside monophosphate metabolic process | biological process | GO:0009167 | 199 | 40 | 16441 | 2138 |
NDUFA5,AK2,ATP6V1A,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,AMPD3,GART,NDUFV1,ENTPD5,ATP5G2,ATIC,MYH3,NDUFA6,FXN,PRPS1,NT5E,PFKFB4,BDNF,PPAT,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,COQ9,SURF1,HK2,NDUFS5,ADK |
| 3.102e-03 | -5.78 | Ybx1 (Y box protein 1) | protein interactions | 22608 | 55 | 16 | 16036 | 2270 |
DDX28,RSL1D1,DKC1,NOP58,HNRNPA3,YARS2,PABPC4,IGF2BP3,NOP56,POP1,SYNCRIP,HNRNPR,ZNF326,IGF2BP1,FBL,PABPC1 |
| 3.102e-03 | -5.78 | POLR3A (polymerase (RNA) III (DNA directed) polypeptide A, 155kDa) | protein interactions | 11128 | 55 | 16 | 16036 | 2270 |
EVA1C,POLR1A,SMARCA4,POLR2A,NEDD4,POLR3G,VPS18,TSR1,POLR3D,POLR3E,GPN1,CRCP,POLR1B,POLR3B,GTF3C3,POLR1C |
| 3.108e-03 | -5.77 | basal_cell_carcinosarcoma | COSMIC cancer mutations | basal_cell_carcinosarcoma | 21 | 8 | 17775 | 2278 |
KMT2D,NRAS,SUFU,ATM,SMARCA4,MET,KMT2C,FGFR1 |
| 3.108e-03 | -5.77 | skin-forearm-carcinoma-basal_cell_carcinosarcoma | COSMIC cancer mutations | skin-forearm-carcinoma-basal_cell_carcinosarcoma | 21 | 8 | 17775 | 2278 |
KMT2D,NRAS,SUFU,ATM,SMARCA4,MET,KMT2C,FGFR1 |
| 3.108e-03 | -5.77 | testis-germ_cell_tumour | COSMIC cancer mutations | testis-germ_cell_tumour | 21 | 8 | 17775 | 2278 |
VPS18,BRAF,NRAS,XRCC2,MET,MAP2K4,NAALADL2,CHAF1A |
| 3.115e-03 | -5.77 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | MSigDB lists | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | 30 | 10 | 17758 | 2279 |
MCM6,MCM10,POLE2,PRIM2,POLA1,MCM5,ORC5,DBF4,MCM2,RPA1 |
| 3.115e-03 | -5.77 | GCM_DPF2 | MSigDB lists | GCM_DPF2 | 30 | 10 | 17758 | 2279 |
TTC1,HMGA2,SUPT4H1,TP53BP1,TAF1,TIMM17A,VPS72,DPF2,COX10,RING1 |
| 3.118e-03 | -5.77 | MYB_LIKE | prosite domains | PS50090 | 6 | 4 | 11866 | 1504 |
EP400,GON4L,DMTF1,SNAPC4 |
| 3.120e-03 | -5.77 | acute_myeloid_leukaemia_associated_with_MDS | COSMIC cancer mutations | acute_myeloid_leukaemia_associated_with_MDS | 177 | 36 | 17775 | 2278 |
ARHGAP26,HMGA2,BRAF,DDX18,NF1,ATRX,BCOR,FAM13A,ABL1,ATXN7L1,SH2B3,SRSF2,SOCS1,ABCA12,MYC,PDS5B,MET,KMT2A,CEP128,SRPK2,SF3A1,VPS13B,NRAS,KMT2D,KDM5A,CUX1,PRDM1,KMT2C,AGAP1,PHF6,PRPF40B,NSD1,HIPK2,ATM,RUNX1,LAMA5 |
| 3.120e-03 | -5.77 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS | 177 | 36 | 17775 | 2278 |
ARHGAP26,HMGA2,BRAF,DDX18,NF1,ATRX,BCOR,FAM13A,ABL1,ATXN7L1,SH2B3,SRSF2,SOCS1,ABCA12,MYC,PDS5B,MET,KMT2A,CEP128,SRPK2,SF3A1,VPS13B,NRAS,KMT2D,KDM5A,CUX1,PRDM1,KMT2C,AGAP1,PHF6,PRPF40B,NSD1,HIPK2,ATM,RUNX1,LAMA5 |
| 3.127e-03 | -5.77 | protein metabolic process | biological process | GO:0019538 | 4189 | 597 | 16441 | 2138 |
PTP4A1,GGT1,ADAM19,DPH1,AARS2,MRPL10,HLTF,NUP160,PABPC4,TOM1L1,MMP7,NEK6,PMAIP1,FNIP2,KDM5C,FXN,CDK6,PPM1K,EIF4E3,NRAS,KLHL23,PTPRM,EHMT1,MSRB3,DCUN1D5,STOML2,DDX3X,BRCA2,SSU72,RAD18,RIOK1,MEF2C,CARS,HERC2,EP400,SLK,TRIO,SIRT7,PIK3R4,CDC73,YARS2,ABCA7,UBE3A,EIF2S2,MED24,ANP32B,MRPL21,PRMT5,MAP3K12,PABPC1,PPA1,PEA15,GTF2H3,TIMM8B,ALG6,WDR61,STAG1,RB1CC1,EIF4A2,USP10,ATAT1,ST6GALNAC3,TRIM37,ABCF1,USP46,IRS1,TASP1,RPL28,EHMT2,CDK9,SENP3,SRP14,C18orf25,MAP2K5,ABCA3,PDK4,DDR2,MYH9,TUBB6,NUP43,ST3GAL6,UBL5,PRKD3,WAC,MMP14,PXK,PERP,KMT2D,GARS,STAMBP,EIF3J,ADAM32,KCNH3,SLC35D1,DSP,FKBP3,FGFR1,TAF2,FBXL5,CDC16,NSMCE2,HIPK2,CAMKMT,RPS6KB1,BRCC3,YEATS2,TRIM36,HMGA2,XPC,TRAK1,JMJD6,GAS6,TRIM22,TGFB2,RSRC1,PSMF1,POM121,TTLL11,TADA3,NPRL2,GATC,SUV39H2,LTN1,FBXL19,RPL22L1,LYPLA2,SPTAN1,FGF9,VPS37A,USP42,MRPS10,UBE2K,UBC,ANXA1,MRPL36,RPA1,OXSR1,TRIB3,NSD1,SRCAP,RARS,STX1A,HERC1,SRD5A3,PTPN4,BMP4,MTMR1,ANAPC4,KDM4C,CUL7,TRIM16,MFGE8,HECTD3,CSNK2A1,RNF43,SEC16A,BIRC2,MAP2K3,ABL2,COPS4,PHKA1,TRIML2,POLE3,PTPRK,RBCK1,ATF4,GCNT2,PPARG,HARS,BAZ2A,CDK4,HSPA5,MED27,COL4A3BP,GMFB,ATG12,SUMO3,BRCA1,KCNH2,DYRK1B,MSRA,EEFSEC,PER1,SOCS4,DPP4,ADAM9,PPP3CC,USP15,CHMP4C,CTU2,TTN,SARS,PGPEP1,FOXO1,CLK1,PRSS3,MAPK8IP3,LAMTOR3,SMAD7,RNF40,PPIL2,GTF2H1,CTR9,SYNJ2,LRSAM1,WARS2,TRAPPC9,CAMKK2,CRADD,USP49,SETD2,OBSCN,MEX3B,TRAPPC6B,TCF7L2,ATXN7,SPAG9,IRAK2,CASS4,HMBS,PTP4A2,GGT7,NAPA,BRSK2,TESC,RNF114,USP7,MPI,CYLD,RPS29,PPP2R2A,RIPK1,RNF24,DENND3,KDM1A,DENR,CAD,JAG1,NUP133,GRIN2C,UBR1,IKBKB,ZDHHC6,ETF1,RNF2,PRMT3,CASP10,PRPF19,SEC24A,KAT8,TUBA1A,NARS,RAB7A,THSD4,AKAP13,ENC1,NUP214,EIF3H,USP36,SMAD3,RANBP2,TIMM17A,ATG7,MED20,EIF2B3,PPIL3,ESCO1,MINK1,HM13,MAP3K13,AGO2,VARS,CSNK1A1,PTPN2,ADH5,CWC27,HIST2H3D,SELT,FBXO31,PCSK6,ADAMTSL3,SMARCAD1,TEX14,HIST1H4J,NEU1,GPC2,EIF2S1,FNTB,USP20,MYRF,TAF12,RPS6KC1,MYCBP2,CUL4A,PRKCSH,PRKAB2,ADAMTS6,PRKCA,UBR5,AARS,EXOC1,RPS16,RNF111,DPH6,FUT11,SEH1L,CSGALNACT2,SETD1B,EYA3,TCEB3,DESI1,ZDHHC14,DOT1L,SPOP,TRRAP,SH3RF1,CCNT1,NSMCE1,CFD,XPNPEP1,CCNB1IP1,BLMH,BMI1,SPOCK2,SPOCK3,PTPN14,WDR75,IFT57,LARS2,ST6GAL1,DPM3,CCDC47,SSR4,TGFBR2,CHD5,IGF2BP3,FKBP1A,PRKCE,ENTPD5,USPL1,MYC,COPS3,PIGG,CNOT4,USE1,SIK3,SYNGAP1,ANAPC13,PTPN12,ARIH2,CAT,SEC31A,EPRS,NSF,HIF1A,UBAP1,SRP68,VCAN,D2HGDH,RIOK3,DPEP1,MACROD1,CNDP2,MAP2K4,SMYD3,HS2ST1,BIRC6,KLHL18,PTPRG,RING1,PHC2,ASNS,KDM2A,SHC1,PPID,UCHL5,MRPS27,SOCS6,TTC3,SERPINH1,KMT2A,CDK12,CASP8AP2,BRD4,PDK1,MTIF2,PCMT1,DLG4,MARCH6,SETD7,SERP1,ERC1,STK10,SNCA,CAMK2D,DNAJA3,FTSJ1,LARGE,ACP1,TRAF3,SETD6,XRCC4,SSH2,BRAF,B4GALT5,TCF3,FARS2,LIAS,IKBKAP,RPS6KA5,GIGYF2,NEDD4,ABL1,PMPCA,COPS7B,HARS2,DYNC2H1,MAP3K14,MBTPS2,CLK2,TTLL5,PXN,TBRG4,PTK2,GUF1,YIF1A,FBXO21,KLHL22,ZDHHC11,RNF138,ATM,APAF1,PGAM5,DDIT3,LRRC41,STK4,KAT6A,IMMP2L,PIGM,FEM1C,EIF3C,KMT2E,NF1,RARS2,PTPRA,TRPM6,RCHY1,PLOD1,PPIL1,BCOR,SIRT2,STK33,PCYOX1L,SLC30A7,MRPS30,SRPRB,ANAPC1,KANSL1,CNIH3,LONRF2,ATG3,ANAPC11,ANAPC10,IPP,HYAL1,JOSD1,SLC35C2,YARS,GALNT18,LONP1,CARM1,PRKACB,TIMM50,SRPK2,ZBTB17,TNK2,TRIM13,FBXW4,SIRT6,LVRN,TFPI,KSR2,HDAC8,CAV1,KMT2C,SGK2,ST3GAL5,TIMM44,PAF1,UBE3D,SUFU,GATA6,HLCS,CTAGE5,ASB3,GALNT10,CLU,COPS6,DCAF5,MTCH1,FBXO45,CHST11,PIGN,FN1,TAF1,SEC24D,UBXN1,ALG8,PCSK7,EVPL,TIMM10,RHBDD1,RNF141,P3H1,ISPD,TENM3,ATP6V0D1,ELP3,PSMA1,EIF2A,CORIN,TMEM241,ISG15,UBE2E1,HERPUD1,EXOC6,MGAT2,EXOC4,CDKAL1,TBL1X,PFDN2,TBCK,DLL4,ASH1L,PIGH,ARSJ,CSTA,PIBF1,RIOK2,FARSA,KCTD11,LYPLAL1,SOCS1,RPS6KL1,ADCK4,MET,TSPAN14,HTRA2,AUP1,NARS2,PARP2,MRRF,NLN,EDEM2,UBR4,WARS,COPS5,ARNTL,DUSP19,FKBP5,DISP1,SCARB1,RNF130,USP11,TSPAN5,SMG1,KLHL24,TNIK,BCKDK,SH2D3A,CAMK1,GFM2,MAN1A1,MRPS11,PRKCH,SEC24C,FBL,RPS6KB2,KDM6B,MARCH9,GPHN,KDM5B,FGF2,SCMH1,MARS,MEN1,EIF5B,PEAK1,TARS,ALG5,AGTPBP1,CUL2,VPS37B,PREPL,MMP16,ZAK,TRAPPC12 |
| 3.136e-03 | -5.76 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | MSigDB lists | REACTOME_CHOLESTEROL_BIOSYNTHESIS | 21 | 8 | 17758 | 2279 |
LSS,IDI1,MVK,FDPS,SQLE,DHCR7,HMGCR,FDFT1 |
| 3.136e-03 | -5.76 | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_UP | MSigDB lists | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_UP | 21 | 8 | 17758 | 2279 |
ASCC3,ATP6V1A,RB1CC1,MARCH6,DLX2,TPM1,RAB30,AHCYL2 |
| 3.139e-03 | -5.76 | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | 183 | 37 | 17758 | 2279 |
HERC2,DCTN3,USP7,SARS,IFT57,NF1,STXBP6,UBXN1,TRAK1,HLTF,SPATS2,COX10,CLINT1,REEP5,UBR5,CAD,RNFT2,DNAJB6,TANK,DCTN4,PMPCA,GTF2H1,ANP32B,VOPP1,USE1,NAA38,DDX41,PSPC1,SCMH1,PNN,MEN1,DENND4A,POLG2,RERE,GLS,TRMT5,MED20 |
| 3.139e-03 | -5.76 | GSE3982_DC_VS_MAC_LPS_STIM_UP | MSigDB lists | GSE3982_DC_VS_MAC_LPS_STIM_UP | 183 | 37 | 17758 | 2279 |
SHQ1,FOXO1,UTP14A,MAP3K13,MAPK8IP3,LETMD1,SMARCA4,NOL3,SEC16A,MGA,LPIN1,TERF2IP,SIPA1L3,SHC1,YLPM1,NUP133,NVL,INTS7,PDS5B,DDX31,CEP63,VCL,PRPS1,CTC1,PDE4A,DDX24,HARS,SLC35D1,PLCB1,POLG2,TARS,MAT2A,TSSC1,CASS4,ABCC3,MUTYH,SMG1 |
| 3.139e-03 | -5.76 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | 183 | 37 | 17758 | 2279 |
DMXL2,EPM2AIP1,RAB11FIP4,PRAF2,TNXB,PCSK7,FOXO3,AHCYL2,EXOC1,CBR4,GLTP,CD44,AGL,PRKACB,ADARB1,SLC6A16,SIK3,TRIM13,ABCC4,IL11RA,JMJD1C,EIF4A2,SETD2,RAP1GAP2,CUX1,RSBN1,CA5B,SON,USP46,STK10,LSM14A,HSPBAP1,HERC1,KLF4,ZNF32,RUNX1,N4BP2L2 |
| 3.139e-03 | -5.76 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 183 | 37 | 17758 | 2279 |
SLC12A7,PRPF38B,PIGN,SFI1,LPIN1,SRPRB,DCTPP1,CAD,C1orf159,PRKD3,TMEM161A,TRIAP1,NCKIPSD,TSPAN14,MGLL,TOMM34,CDC37,LRRC20,PEA15,FGF9,LIMA1,WDR18,ARHGEF10,BCS1L,RYR2,CAMSAP2,SGK2,MAT2A,USP36,ASCC3,CHD3,CUL2,MKL2,CNDP2,EIF2B3,PRKAR2A,TMEM33 |
| 3.139e-03 | -5.76 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 183 | 37 | 17758 | 2279 |
ARHGAP26,NDUFAF2,HSD17B10,MAP1S,CMTM3,MBNL1,MAP2K3,ABL2,PRKD3,ASAP1,JAZF1,PTGS1,TTC3,ZNF710,ERRFI1,AGL,SNX29,TMC7,SLC38A6,EVL,SKAP2,ABCC4,LAMC1,TLE3,NLN,NXN,PEAK1,SH3GL1,MSRA,PEMT,ATM,TRAF3,SCARB1,BPNT1,NRP1,BRWD3,PKIB |
| 3.143e-03 | -5.76 | CHROMATIN_MODIFICATION | MSigDB lists | CHROMATIN_MODIFICATION | 55 | 15 | 17758 | 2279 |
KAT8,NSD1,SUPT4H1,SUV39H2,SMARCC1,SET,EHMT1,HDAC8,SIRT2,RSF1,ARID1A,MAP3K12,RPS6KA5,CARM1,KAT6A |
| 3.143e-03 | -5.76 | DNA_DEPENDENT_DNA_REPLICATION | MSigDB lists | DNA_DEPENDENT_DNA_REPLICATION | 55 | 15 | 17758 | 2279 |
ABL1,EXO1,RFC4,POLB,PMS1,RFC3,PRIM2,POLA1,ORC5,MSH3,MLH1,POLG2,MUTYH,RPAIN,RPA1 |
| 3.153e-03 | -5.76 | Elongator holoenzyme complex | cellular component | GO:0033588 | 6 | 4 | 17570 | 2233 |
IKBKAP,ELP2,ELP5,ELP3 |
| 3.158e-03 | -5.76 | single-stranded DNA binding | molecular function | GO:0003697 | 86 | 21 | 16491 | 2164 |
PMS1,MCM6,MCM10,XPC,C10orf2,TSN,MLH1,SSBP2,ANXA1,RPA1,SUB1,BRCA2,SPEN,XRCC2,RAD51B,MSH3,PURB,SSBP1,YBX3,LONP1,CTC1 |
| 3.172e-03 | -5.75 | SSRP1 (structure specific recognition protein 1) | protein interactions | 6749 | 101 | 25 | 16036 | 2270 |
POLB,MCM6,CUL7,ATRX,POLR1A,SMARCAD1,ZC3H18,CSNK2A1,JMJD6,BRCA1,MCM2,PHGDH,POLR2A,PAF1,APLF,FMNL1,MCM5,SEC24C,COPS5,POLR3E,H2AFX,CTR9,RNF2,RAN,NOLC1 |
| 3.172e-03 | -5.75 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | 105 | 24 | 17758 | 2279 |
SLC40A1,SLC48A1,LIMA1,PIGH,SMAD7,VIM,SLC29A1,SPATS2L,SOX4,FOSL2,BHLHE40,SLC6A8,NBEAL1,DDIT4,SKIL,IDI1,ASNS,PMEPA1,SQLE,HMBS,NRP1,RPS6KC1,ZAK,CHMP4C |
| 3.175e-03 | -5.75 | SH3GLB1 (SH3-domain GRB2-like endophilin B1) | protein interactions | 51100 | 60 | 17 | 16036 | 2270 |
USP7,ARHGAP17,TFIP11,ACTR3,PSMA1,RANGAP1,XPO7,SYNJ1,SH3GL1,WARS,FLAD1,TPD52L2,P3H1,GADD45A,CUL2,ADAM9,LPP |
| 3.175e-03 | -5.75 | HP1BP3 (heterochromatin protein 1, binding protein 3) | protein interactions | 50809 | 60 | 17 | 16036 | 2270 |
CUL7,UTP14A,TRA2A,SIRT7,ZC3H18,NFIA,RSL1D1,ZNF346,SON,RIOK2,NOP16,ZNF326,SHMT2,RNF2,BMI1,FTSJ3,TMPO |
| 3.193e-03 | -5.75 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 36 | 17758 | 2279 |
ARHGAP26,PDCD7,FAM13A,SAFB2,PAG1,FAM50A,ABCA5,CFDP1,NISCH,DTNBP1,FNIP2,FUT11,POLR1E,DENND1A,LONP1,MOSPD1,SAP30,VPS37A,RAB7A,COL4A3BP,POU2F1,RBM28,SLC26A11,PIK3CB,VAC14,TBC1D2,ZBTB25,ZFP62,ARID3B,NSMCE2,HIPK2,ABCC3,C7orf50,RBPJ,SLC25A26,SMG1 |
| 3.194e-03 | -5.75 | AAGCACT,MIR-520F | MSigDB lists | AAGCACT,MIR-520F | 227 | 44 | 17758 | 2279 |
DLL4,AK2,MINK1,ITFG1,UBXN1,KLHL18,LETMD1,WDR26,WDR37,RPS6KA5,MTUS1,RAP1A,ZKSCAN1,JAZF1,SLC38A2,RDX,RAPGEFL1,IGF2BP1,MAP3K14,PRKACB,HN1,GATAD2B,DDHD1,AEBP2,RB1CC1,ZNF654,KCNMA1,USP42,ZNFX1,MBNL2,NAPEPLD,DDX3X,BAZ1A,LMBR1L,ZNF436,PURB,DPP4,CNOT6,VASH2,IQSEC2,ZBTB11,RABEP1,MEF2C,ATXN7L2 |
| 3.203e-03 | -5.74 | response to oxidative stress | biological process | GO:0006979 | 339 | 62 | 16441 | 2138 |
TRPM2,FOXO1,PRDX6,PPARGC1B,PAX2,LIAS,SIRT2,FOXO3,HSPA1A,ABL1,SHC1,SLC7A11,TMEM161A,STC2,MMP14,HYAL1,PTGS1,WNT16,NDUFA6,FXN,OGG1,LONP1,HTRA2,PTPRK,KDM6B,PXN,ATF4,PDK1,ATOX1,LDHA,MSRB3,ABCC2,APTX,SGK2,KLF6,MTR,MGST1,ANXA1,SLC23A2,SNCA,HSPA1B,PYCR1,CAT,OXSR1,MSRA,ETFDH,ZNF622,PXDN,ALAD,PDLIM1,HIF1A,G6PD,ARL6IP5,KLF4,ARNTL,MPV17,ADAM9,DPEP1,BMP4,TPM1,TXN2,MAPT |
| 3.205e-03 | -5.74 | SGF29 (SAGA complex associated factor 29) | protein interactions | 112869 | 65 | 18 | 16036 | 2270 |
TCF12,BANP,DTNB,SSFA2,ACTG1,WDR37,SUPT20H,SH3GL1,C1orf122,TAF9B,TADA3,ATXN7,TRRAP,RABGAP1L,BUD31,TAF12,YEATS2,ATXN7L2 |
| 3.237e-03 | -5.73 | Myb-like_dom | interpro domains | IPR017877 | 6 | 4 | 18293 | 2341 |
EP400,GON4L,DMTF1,SNAPC4 |
| 3.238e-03 | -5.73 | SENESE_HDAC1_TARGETS_UP | MSigDB lists | SENESE_HDAC1_TARGETS_UP | 423 | 74 | 17758 | 2279 |
SPRED2,FAM208B,NPAS2,COBLL1,ADAMTS6,ZBED2,PPFIBP1,LETM2,SETD5,GLYR1,TRIML2,MET,CDK6,CSGALNACT2,MOSPD1,TMPO,ANTXR2,ABCC4,SSFA2,UPP1,GPCPD1,TFPI,MCL1,MGST1,TAF9B,CXADR,ZC3H12A,PLIN2,DDX3X,SLC39A14,SLC7A1,DUS3L,ITGA2,TMEM158,ZMAT3,CHST11,FN1,SUPT6H,ITPRIP,TRIO,SMG7,IGF2BP2,AKT1S1,TGFBR2,PIP4K2A,MBNL1,NAMPT,IGF2BP3,GART,MLX,SLC7A11,MYC,DSG2,CELF1,ERRFI1,CD44,NAV3,TOP1,PXN,PSAT1,PRIM2,LSM12,TEAD1,LIG4,USP10,PTPN12,PHACTR2,IL6R,ZNF655,EPRS,SNAP23,IRAK2,SLC16A1,MTMR1 |
| 3.243e-03 | -5.73 | MODULE_16 | MSigDB lists | MODULE_16 | 497 | 85 | 17758 | 2279 |
PTP4A1,TCF12,ADAM19,TRIM16,RIBC2,DDX19A,SLC2A1,TNXB,KLHL18,CSNK2A1,GYG1,CSTA,RAC3,MAP2K3,CAD,RAP1A,SRSF2,ASNS,ACD,AP1M1,WIZ,CORO1A,FHIT,KDM5C,HRG,SRRM2,OGG1,TRIP13,PRPF19,PRAME,BRD4,NPM3,PSMG1,SEMA3F,MCM2,CHAF1A,PLIN2,HTR7,HPRT1,RBBP8,INSIG1,ADNP,CFD,H2AFX,PPP3CC,ARC,MAGI1,NOLC1,BLMH,MCM6,AK2,TAF1,HSD17B10,ZIC2,SLC7A11,MYC,COPS3,MCM5,SHMT2,LRP3,SERBP1,SLC25A1,MYB,FDFT1,FADS1,EXOSC2,GTF2H3,MSX1,PXN,RREB1,KCNQ3,APEX1,ZBED4,SULT4A1,ADSL,ARID1A,UBE2E1,SMPDL3B,RPA1,ANXA1,SYNCRIP,GADD45A,NCBP2,NFKBIB,SLC43A1 |
| 3.246e-03 | -5.73 | WINTER_HYPOXIA_UP | MSigDB lists | WINTER_HYPOXIA_UP | 88 | 21 | 17758 | 2279 |
PFKFB4,XPO5,SLC2A1,GMFB,LDHA,IGF2BP2,RNF24,BMS1,SLC6A8,METTL22,NUDT15,ANGPTL4,KCTD11,TPD52L2,S100A10,TRMT5,SNX24,EIF2S1,VAPB,SLC16A1,RAN |
| 3.247e-03 | -5.73 | DNA Double-Strand Break Repair | REACTOME pathways | R-HSA-5693532 | 162 | 35 | 8202 | 1117 |
HERC2,RMI1,ABL1,BRE,SLX4,XRCC2,TIMELESS,ATRIP,SPIDR,RFC4,RFC3,SIRT6,POLK,PARP2,EYA3,TOP3A,LIG4,HIST1H2BL,HIST1H4J,BRCA1,UBC,RPA1,EXO1,RBBP8,BRCA2,POLE2,KDM4B,PALB2,TP53BP1,RAD51B,H2AFX,ATM,EME1,BRCC3,XRCC4 |
| 3.248e-03 | -5.73 | ATRIP (ATR interacting protein) | protein interactions | 84126 | 41 | 13 | 16036 | 2270 |
HERC2,CEP164,FAM208B,RIBC2,CDK9,TIMELESS,ATM,BRCA1,MCM2,POLR1C,CCDC28B,RPA1,CLK2 |
| 3.248e-03 | -5.73 | SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2) | protein interactions | 6603 | 41 | 13 | 16036 | 2270 |
DPF3,SMARCC1,SMARCAD1,DPF2,SMARCA4,RNF2,UPF2,BRCA1,TBL1X,ARID1A,BMI1,ARID1B,SMARCB1 |
| 3.248e-03 | -5.73 | ERCC6 (excision repair cross-complementation group 6) | protein interactions | 2074 | 41 | 13 | 16036 | 2270 |
USP7,CUL7,CUL4A,COPS4,COPS3,POLR1A,SSBP1,BRCA1,COPS6,OGG1,POLR2A,UBC,RPA1 |
| 3.272e-03 | -5.72 | WALLACE_PROSTATE_CANCER_DN | MSigDB lists | WALLACE_PROSTATE_CANCER_DN | 6 | 4 | 17758 | 2279 |
LAMA4,AKAP12,CAV2,RAP1B |
| 3.272e-03 | -5.72 | KAUFFMANN_MELANOMA_RELAPSE_DN | MSigDB lists | KAUFFMANN_MELANOMA_RELAPSE_DN | 6 | 4 | 17758 | 2279 |
TOM1L2,N4BP2,TERF2,NFIA |
| 3.274e-03 | -5.72 | DROSHA (drosha, ribonuclease type III) | protein interactions | 29102 | 32 | 11 | 16036 | 2270 |
YLPM1,ZCCHC8,SKIV2L2,KHDRBS1,ZNF512B,PSMA1,EVPL,MEN1,BMI1,CARM1,SRPK2 |
| 3.274e-03 | -5.72 | ARID1B (AT rich interactive domain 1B (SWI1-like)) | protein interactions | 57492 | 32 | 11 | 16036 | 2270 |
DPF3,SMARCC1,KDM5B,DPF2,CUL2,SMARCD3,SMARCA4,ARID1A,PRMT5,ARID1B,SMARCB1 |
| 3.286e-03 | -5.72 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | 165 | 34 | 17758 | 2279 |
BANP,PTP4A1,EGR1,ID2,TUBE1,CHAC1,SLC9B2,ST3GAL6,UBTD2,PHLDA2,ZSCAN5A,DDIT4,SFR1,ABL2,ASNS,PMAIP1,CYB5D1,SLC38A2,FNIP2,SESN2,GARS,SLC3A2,PPARG,UPP1,TEX14,FERMT2,DENND4A,ARL5B,NEU1,ZC3H12A,SPAG9,GADD45A,INSIG1,CSRNP1 |
| 3.308e-03 | -5.71 | WTGAAAT_UNKNOWN | MSigDB lists | WTGAAAT_UNKNOWN | 579 | 97 | 17758 | 2279 |
GNB3,TRERF1,BIRC6,PRKAB2,PDK4,C1QTNF7,PPP2R2A,CSNK2A1,COBLL1,RNF43,WNT2B,NEK6,IKZF5,NSRP1,ATP5G2,FSIP2,JAZF1,ANKRD11,NBEA,PAK1IP1,CHD2,ADCK4,CEP135,OGG1,CDK6,MAML3,SRPK2,SOBP,SLC38A6,FMNL3,GPM6A,GARS,NRAS,GDPD1,EHMT1,TCEB3,CUX1,C10orf76,SLC35D1,PEX1,C1orf122,MLLT10,SMAD3,ARHGAP21,MSX2,EIF4ENIF1,COPS5,LUC7L3,HOXA3,CSMD3,RPS6KB1,PRPF4,NRP1,SPOCK2,MID1,MEF2C,HMGA2,FN1,CA11,ANKRD17,RHOBTB1,PAX2,UBXN1,DLGAP4,VPS45,ZFP36L1,RCAN1,SSR4,INPP1,GIGYF2,NEDD4,MAN1A1,PRKCE,STC2,UPF2,GMDS,ERRFI1,SOX6,SPTAN1,NAV3,TEAD1,PRDM16,IDH3G,PTK2,R3HDM2,ARRDC4,ZNF407,KLF6,RERE,DKK1,EXOC6,MTHFD2,HIF1A,RRAGA,SQLE,C18orf25,KAT6A |
| 3.309e-03 | -5.71 | stem cell population maintenance | biological process | GO:0019827 | 145 | 31 | 16441 | 2138 |
BRAF,CUL4A,FOXO1,FGF2,PRDM16,MED27,PBX1,LIG4,SOX4,FOXO3,CDC73,FGFR1,POLR2A,TCF7L2,SKI,PAF1,TCF7L1,JAG1,EIF4ENIF1,ZNF358,KLF4,VPS72,MED15,TBX3,CTR9,MED24,RBPJ,IGF2BP1,SETD6,DIS3L2,KAT6A |
| 3.309e-03 | -5.71 | SANSOM_APC_TARGETS_UP | MSigDB lists | SANSOM_APC_TARGETS_UP | 117 | 26 | 17758 | 2279 |
WDR75,SLC40A1,MSX1,MCM6,EGR1,APEX1,PSAT1,MRI1,HES6,MARCKSL1,RNF43,IMPDH2,QSER1,SOX4,MCM2,TGFBR2,SLC39A14,EIF2S2,BCAS2,HNRNPR,MAD1L1,SHF,KIAA0922,CD44,ZC3H8,CDC37 |
| 3.314e-03 | -5.71 | BIOCARTA_CARM_ER_PATHWAY | MSigDB lists | BIOCARTA_CARM_ER_PATHWAY | 35 | 11 | 17758 | 2279 |
NCOR2,GTF2A1,SPEN,HDAC8,BRCA1,NRIP1,SRA1,PELP1,POLR2A,CARM1,MEF2C |
| 3.314e-03 | -5.71 | chr5q14 | MSigDB lists | chr5q14 | 35 | 11 | 17758 | 2279 |
DMGDH,SERINC5,PAPD4,ARRDC3,SSBP2,XRCC4,ATP6AP1L,NR2F1,RIOK2,MEF2C,POLR3G |
| 3.314e-03 | -5.71 | RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS | MSigDB lists | RNA_SPLICINGVIA_TRANSESTERIFICATION_REACTIONS | 35 | 11 | 17758 | 2279 |
GEMIN5,SCAF11,SNW1,PHF5A,PRPF31,SFSWAP,TRA2A,SF3A3,CELF1,SRPK2,SF3A1 |
| 3.315e-03 | -5.71 | REACTOME_TRANSCRIPTION | MSigDB lists | REACTOME_TRANSCRIPTION | 196 | 39 | 17758 | 2279 |
TAF1,POLR1A,NFX1,SNAPC4,ELL,POLR3D,RRN3,SRSF2,PTRF,MBD2,GTF2H1,HIST2H3D,GTF3C3,POLR3B,POLR1B,CPSF3,LSM10,SNAPC5,GTF2H3,RNMT,TCEB3,POU2F1,HIST1H2BL,HIST1H4J,SUPT5H,POLR3A,POLR2A,UBTF,SUPT4H1,GTF2A1,EHMT2,CCNT1,CDK9,TAF4,POLR3E,H2AFX,NCBP2,TAF12,POLR1C |
| 3.315e-03 | -5.71 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | 196 | 39 | 17758 | 2279 |
USP7,NCOR2,SYT17,CUL4A,UBN1,CAMK1,ISG20L2,AP1B1,INPP1,PABPC4,NDUFS7,CAMTA2,SOCS1,TBC1D22A,ATXN2,CBR4,ANP32B,AHCYL1,MPST,HNRNPM,TBC1D8,SPTAN1,DEAF1,FOXN3,MARS,ECH1,STOML2,SEC31A,TRRAP,HELZ,CLEC16A,CFD,WDR7,SLC25A11,SCARB1,TPM1,TMEM158,GCSH,HRH1 |
| 3.315e-03 | -5.71 | GSE17721_LPS_VS_POLYIC_8H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDM_DN | 196 | 39 | 17758 | 2279 |
EIF3C,ZCCHC8,CERS5,C14orf159,ABHD6,FOXO3,AARS,NEDD4,C1orf159,ADH5,ATG3,SOCS6,INTS12,SYNJ2,TMEM14C,MPST,RABEPK,PDK1,SLC38A1,ARID5B,LDHA,TOP3A,RNH1,VIM,SEMA3F,DDX60,ISG15,ECH1,NAP1L5,KLHL22,ALG5,LRRC40,ZBTB12,LARGE,CTAGE5,DNAJC12,GGT7,MTMR1,HS2ST1 |
| 3.315e-03 | -5.71 | ATACTGT,MIR-144 | MSigDB lists | ATACTGT,MIR-144 | 196 | 39 | 17758 | 2279 |
PTP4A1,TTN,FOXO1,RHOBTB1,CLK1,ARID2,PAFAH1B1,KIAA0232,TRIO,SEMA6A,RPGRIP1L,NEDD4,SLC7A11,ATP5G2,RNF111,CAV2,PKNOX1,NAV3,SOBP,ANTXR2,MSX1,GCNT2,STAG1,WDFY3,ANK2,ARRDC3,USP42,ARID5B,ATXN1,MAP7D1,ST6GALNAC3,ARID1A,FAM126B,SON,SLC23A2,KPNA1,LSM14A,NR2F2,KAT6A |
| 3.334e-03 | -5.70 | MITOCHONDRIAL_INNER_MEMBRANE | MSigDB lists | MITOCHONDRIAL_INNER_MEMBRANE | 66 | 17 | 17758 | 2279 |
TIMM8B,BCS1L,OPA1,TIMM10,NDUFS7,ATP5D,TAMM41,NDUFV1,ATP5G2,TIMM17A,MPV17,SURF1,PMPCA,SLC25A11,NDUFA6,SLC25A1,TIMM50 |
| 3.342e-03 | -5.70 | skin | COSMIC cancer mutations | skin | 17124 | 2217 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,PNMA1,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,SUCLG1,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,SPOP,OSBPL1A,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,AMBRA1,NOS1AP,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,PRKCE,FKBP1A,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,PUSL1,RAB10,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,NDUFAF2,SLC48A1,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DENND4A,SON,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,WDR26,ATF7IP,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,CPOX,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,RABAC1,DAGLA,KIDINS220,SRRD,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,ZNF330,PREPL,ZAK,ARHGAP27 |
| 3.351e-03 | -5.70 | ACTGTAG,MIR-139 | MSigDB lists | ACTGTAG,MIR-139 | 123 | 27 | 17758 | 2279 |
TCF12,AEBP2,PDE4A,ATRX,ANK2,ARRDC3,ATXN1,SMARCA4,FOXP1,PDE3A,MAT2A,PHF6,DDIT4,DCBLD2,ZFAND3,DDX3X,CHD7,NME7,LSM14A,VPS37B,NDRG4,TROVE2,TSPAN5,ZNF532,TOP1,TMCC1,HMGCR |
| 3.352e-03 | -5.70 | ATPase_dyneun-rel_AAA | interpro domains | IPR011704 | 13 | 6 | 18293 | 2341 |
DYNC1H1,DNAH2,DYNC2H1,MDN1,DNAH1,VWA8 |
| 3.352e-03 | -5.70 | tRNAsynth_1a_anticodon-bd | interpro domains | IPR009080 | 13 | 6 | 18293 | 2341 |
CARS,MARS,VARS,RARS,LARS2,RARS2 |
| 3.368e-03 | -5.69 | cellular nitrogen compound catabolic process | biological process | GO:0044270 | 392 | 70 | 16441 | 2138 |
LIN28B,PAPD4,DCP1B,RPS29,PPP2R2A,NT5C3A,HMOX2,TNKS1BP1,PDE3A,PABPC4,EDC3,AMPD3,RPS16,ERI1,NT5C,ETF1,OGG1,MPST,SKIV2L,SKIV2L2,ITPA,UPP1,ALDH1L2,NUDT15,PDE8B,HPRT1,NOCT,MUTYH,SMG1,DMGDH,DROSHA,TATDN3,PDE4B,SMG7,ZFP36L1,MLH1,RNASEH2B,PARN,DCTPP1,PDE10A,UPF2,EXOSC4,ERI3,NT5M,CNOT4,PABPC1,DIS3L2,NT5E,EXOSC2,WDR61,PDE4A,EIF4A2,DHX34,RNH1,EXOG,PDE2A,PDE3B,CTIF,POP1,CAT,KPNA1,RPL28,ZCCHC6,ATM,CNOT6,NCBP2,DPEP1,TATDN1,PDE9A,AGO3 |
| 3.377e-03 | -5.69 | central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I | 13 | 6 | 17775 | 2278 |
RNF130,BRAF,NRAS,KIAA1549,GNAI1,CLCN6 |
| 3.384e-03 | -5.69 | EP300 (E1A binding protein p300) | protein interactions | 2033 | 477 | 89 | 16036 | 2270 |
TCF12,ZNF76,POLB,ASCC1,TRERF1,NPAS2,SIRT2,FOSL2,PRKCA,PELP1,KDM1A,VPS18,BCAS2,SREBF2,ZEB1,ZNF148,RAN,ETV1,CARM1,ZBTB17,TNK2,ATF4,BRD4,PPARG,HSPA5,BRCA1,MEF2D,SOX4,MCM2,SMAD3,ZC3H12A,VDR,DYRK1B,FBXL5,CDC16,GATA6,TP53BP1,KLF4,HIPK2,ARNTL,ATG7,RPS6KB1,RUNX1,ANXA2,COPS6,BMI1,MAPT,MEF2C,BANP,NCOR2,EGR1,FOXO1,TCF3,SMAD7,RPS6KA5,FOXO3,HIST2H2AB,TADA3,ABL1,SUB1,SNW1,MCM5,MYC,GTF3C3,PCK2,CD44,CNOT4,N4BP2,TERF2,RPS6KB2,MYB,DDX24,APEX1,TCF7L2,POLR2A,UBC,RERE,ATXN7,SRCAP,MYBBP1A,HIF1A,HERC1,SET,SENP3,ZRANB2,NCOR1,NR2F2,DDIT3,KAT6A |
| 3.385e-03 | -5.69 | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | MSigDB lists | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | 464 | 80 | 17758 | 2279 |
CYP24A1,MVK,NPAS2,PRKAB2,LPCAT2,TNFRSF21,PPARGC1B,CERS5,LPCAT3,ARSJ,SYNJ1,LCLAT1,LPIN1,DECR1,NRF1,IDI1,SREBF2,LPIN2,ME1,SLC27A5,MGLL,PRKACB,ACSL5,MCEE,ACADS,PPARG,GPCPD1,MED27,COL4A3BP,CAV1,MED16,PITPNB,HSD3B7,PLIN2,LSS,PEMT,ARNTL,ABCC3,MED20,SCARB1,NCOR2,PIK3R4,MED13L,MED18,PLA2G12A,PIP4K2A,SLC25A20,PI4KB,MED24,VAPB,SYNJ2,PNPLA3,LPCAT1,HSD17B12,SLC25A1,HMGCR,FDFT1,FADS1,TEAD1,AGPAT4,PCCA,ELOVL6,SMARCD3,CPT1A,ANGPTL4,PIK3CB,VAC14,NEU1,RDH11,TRIB3,ACOX1,FDPS,SRD5A3,SQLE,PSAP,GPAM,NCOR1,TBL1X,MTMR1,DHCR7 |
| 3.385e-03 | -5.69 | central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I | 17 | 7 | 17775 | 2278 |
RNF130,BRAF,NRAS,NF1,KIAA1549,GNAI1,CLCN6 |
| 3.385e-03 | -5.69 | optic_nerve | COSMIC cancer mutations | optic_nerve | 17 | 7 | 17775 | 2278 |
RNF130,BRAF,NRAS,NF1,KIAA1549,GNAI1,CLCN6 |
| 3.386e-03 | -5.69 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_UP | 190 | 38 | 17758 | 2279 |
SERINC5,AUH,UBN1,TRIO,TMEM109,SLC29A1,AARS,PITPNM1,NPRL2,ASNS,ATP5G2,AMOT,LPCAT1,EXOSC2,GARS,CRADD,TSTA3,HARS,EIF3J,FOXN3,RAPGEF4,HOMER2,MARS,CLNS1A,HERPUD1,SEC31A,ASCC3,ADNP,CHD3,TP53BP1,COQ9,CDK9,PEMT,ZNF81,FNTB,UMPS,MYOM2,RFXAP |
| 3.386e-03 | -5.69 | GSE14308_TH1_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_TH1_VS_NATURAL_TREG_UP | 190 | 38 | 17758 | 2279 |
YDJC,VIPR1,COMMD10,CHMP2A,TMEM63C,SARS,STX8,SLC48A1,SEC24D,CCDC53,PRKCSH,FANCD2,JMJD6,SIRT2,SPATS2,PTPRG,RPS6KA5,ZNF239,SUV39H2,FNIP2,ANP32B,CMPK1,CEP135,ACTR3B,PDK1,TMEM126A,RAP1GAP2,TFPI,SCFD2,TBRG4,ANGPTL4,LSG1,RAD54B,YIF1A,POP1,COPS5,NSMCE1,SURF1 |
| 3.386e-03 | -5.69 | GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_WT_VS_TRAF6KO_DAY6_EFF_CD8_TCELL_UP | 190 | 38 | 17758 | 2279 |
DCTN3,ASH1L,CHST11,DCP1B,TBCCD1,IKBKAP,HSPA1A,METTL16,RGS17,HVCN1,ZSWIM7,THADA,AGL,TMEM120B,C6orf89,VOPP1,DDHD1,CRADD,STAMBP,C2orf76,ARHGAP39,EYA3,SLC35G1,MINA,COL4A3BP,ATAT1,ZDHHC14,EIF5B,ANGPTL4,HSPA1B,ATXN7,BRCA2,DUS3L,HIC2,TSSC1,TSEN2,NR2C2AP,LRCH1 |
| 3.386e-03 | -5.69 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP | 190 | 38 | 17758 | 2279 |
HMGA2,BANP,EPM2AIP1,CDC42EP2,PDE4B,FOSL2,FOXO3,NAMPT,SNW1,NRF1,PMAIP1,RELB,MET,CEP135,LPCAT1,ACSL5,SIK3,GON4L,UPP1,EPS15L1,DHX34,FERMT2,MCL1,IL6R,AKAP13,OASL,KLF6,UBR4,TJAP1,SH3GL1,ZC3H12A,ZNF266,ARID3B,TP53BP1,ZCCHC6,RUNX1,HRH1,TRIM36 |
| 3.386e-03 | -5.69 | WENG_POR_TARGETS_LIVER_UP | MSigDB lists | WENG_POR_TARGETS_LIVER_UP | 40 | 12 | 17758 | 2279 |
ANTXR2,ASNS,IDI1,ENTPD5,ACTG1,FDPS,LGALS1,ANXA5,SQLE,C11orf54,CYB5B,PGD |
| 3.386e-03 | -5.69 | NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | NUCLEOTIDE_METABOLIC_PROCESS | 40 | 12 | 17758 | 2279 |
HPRT1,AMPD3,PPAT,OLA1,UMPS,NT5C,ME1,FHIT,CMPK1,NT5M,ADK,PGD |
| 3.387e-03 | -5.69 | PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN | MSigDB lists | PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN | 141 | 30 | 17758 | 2279 |
SEPHS2,NAA38,STAG1,MTIF2,WDR13,LAMTOR3,ATG12,ID2,APRT,PNN,SOX4,SYNJ1,KLF6,DKK1,KLHL22,MSX2,NDUFV1,BCAS2,ZNF330,ZNHIT6,RABGAP1L,CEBPZ,NOC3L,CD44,DHCR7,ECHDC1,TROVE2,BAG1,MOSPD1,PTPRK |
| 3.388e-03 | -5.69 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | 135 | 29 | 17758 | 2279 |
SEC24A,GGT1,TSTA3,MYO10,ELOVL6,NUDT15,BZW2,PHLDA2,ETFB,SLC39A11,IQGAP2,SLC39A14,DSC2,NME7,SH3RF1,IRAK2,ABCC3,ARHGAP12,FNIP2,S100A14,CMPK1,GMDS,PERP,GPATCH4,BAG1,SGSM3,CHMP4C,FDFT1,HN1 |
| 3.395e-03 | -5.69 | MODULE_261 | MSigDB lists | MODULE_261 | 94 | 22 | 17758 | 2279 |
WDR75,NRAS,MIOS,DBF4,TRAK1,MARCH6,RLF,SEC16A,DDX49,STK10,PAG1,C1orf159,INSIG1,PMAIP1,INTS7,DNAJA3,FMNL1,AEN,SYNJ2,NMD3,STK4,LPP |
| 3.396e-03 | -5.69 | purine nucleoside monophosphate metabolic process | biological process | GO:0009126 | 200 | 40 | 16441 | 2138 |
NDUFA5,AK2,ATP6V1A,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,AMPD3,GART,NDUFV1,ENTPD5,ATP5G2,ATIC,MYH3,NDUFA6,FXN,PRPS1,NT5E,PFKFB4,BDNF,PPAT,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,COQ9,SURF1,HK2,NDUFS5,ADK |
| 3.401e-03 | -5.68 | 3_5_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY | MSigDB lists | 3_5_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY | 13 | 6 | 17758 | 2279 |
PDE4A,PDE2A,PDE3B,PDE10A,PDE3A,PDE4B |
| 3.405e-03 | -5.68 | negative regulation of nuclear division | biological process | GO:0051784 | 60 | 16 | 16441 | 2138 |
TEX14,CSNK2A1,MAD2L2,UBE2E1,TOM1L1,KLHL22,ANAPC1,CDC16,TOM1L2,ANAPC11,MAD1L1,ANAPC10,ATM,BMP4,DMRT1,ANAPC4 |
| 3.405e-03 | -5.68 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032435 | 60 | 16 | 16441 | 2138 |
UBXN1,TEX14,CSNK2A1,MAD2L2,UBE2E1,KLHL22,ANAPC1,CDC16,SMARCC1,WAC,ANAPC11,MAD1L1,ANAPC10,ATM,FHIT,ANAPC4 |
| 3.405e-03 | -5.68 | positive regulation of cell cycle phase transition | biological process | GO:1901989 | 60 | 16 | 16441 | 2138 |
CUL4A,BRD4,ANKRD17,CDK4,PLRG1,PBX1,SMARCD3,PPP1R1C,PLCB1,ANXA1,DDX3X,NSMCE2,ANAPC11,RAD51B,RDX,LSM10 |
| 3.413e-03 | -5.68 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP | 17 | 7 | 17758 | 2279 |
TUBE1,CHAC1,MTHFD2,ATF4,DDX10,STC2,DDIT4 |
| 3.416e-03 | -5.68 | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | MSigDB lists | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 318 | 58 | 17758 | 2279 |
SPRED2,CHMP2A,MCM10,CELSR1,KIAA0232,PBX1,RNF43,IGF2BP2,TUBB6,PHGDH,REEP5,TOM1L1,PRKD3,MCAM,MCM5,MYC,NBEA,GREB1,CD44,PNMA1,CASP8AP2,MYB,DSC3,IFRD1,MPP6,EVL,LIMA1,MYO10,SEMA3F,TMEM123,EFHC1,DKC1,FOXC1,KIF16B,PLIN2,GLS,FBXL5,IRS1,TCF7L1,RETSAT,AHNAK,MTHFD2,SYNCRIP,DSC2,KDM4B,DNAJC1,DCXR,MKL2,TBX3,RNF138,DNAJC12,SLC16A1,SEMA3C,GALNT10,RABEP1,YEATS2,MID1,MAPT |
| 3.419e-03 | -5.68 | HDAC5 (histone deacetylase 5) | protein interactions | 10014 | 343 | 67 | 16036 | 2270 |
USP7,EIF3C,PRDX6,PPP2R2A,MYH9,CSNK2A1,BCOR,HSPA1A,HNRNPA3,HNRNPLL,CAD,PRKD3,CAMTA2,ANKRD11,RAN,SF3A1,PRPF19,TUBA1A,HSPA5,PCMT1,MEF2D,MCM2,NUP214,SMAD3,DDX3X,DYRK1B,IKZF4,HNRNPR,KLF4,SLC25A11,MEF2C,NCOR2,MCM6,CAMK1,SMAD7,HSD17B10,PRPF39,PHGDH,HR,MCM5,SHMT2,IGF2BP1,PRMT5,ALDH18A1,NRIP1,PABPC1,SLC25A1,MTHFD1,TOP1,NUDC,SIK3,KDM5B,LDHA,MARS,IMPDH2,TARS,ECH1,NEU1,EPRS,RARS,TRAP1,HIF1A,TBX3,NCOR1,TBL1X,PGAM5,DDIT3 |
| 3.429e-03 | -5.68 | CIR1 (corepressor interacting with RBPJ, 1) | protein interactions | 9541 | 12 | 6 | 16036 | 2270 |
SNW1,NCOR2,RBPJ,SRSF2,NEK6,SAP30 |
| 3.429e-03 | -5.68 | PRCC (papillary renal cell carcinoma (translocation-associated)) | protein interactions | 5546 | 12 | 6 | 16036 | 2270 |
CSNK2A1,TOE1,SRSF2,MAD2L2,PPIL2,PRPF19 |
| 3.429e-03 | -5.68 | WDR43 (WD repeat domain 43) | protein interactions | 23160 | 12 | 6 | 16036 | 2270 |
RNF2,CUL7,FBL,UBR5,UTP4,SIRT7 |
| 3.429e-03 | -5.68 | DCAF4 (DDB1 and CUL4 associated factor 4) | protein interactions | 26094 | 12 | 6 | 16036 | 2270 |
USP7,CUL4A,COPS6,DKC1,COPS5,COPS3 |
| 3.429e-03 | -5.68 | PRPF3 (pre-mRNA processing factor 3) | protein interactions | 9129 | 91 | 23 | 16036 | 2270 |
SART1,SNU13,PRPF31,TFIP11,TRA2A,PLRG1,FRA10AC1,SF3A3,BRCA1,SON,NOP58,CTNNBL1,BCAS2,CCDC85B,PRPF4,RBM26,FBL,SRRM2,PABPC1,HNRNPM,SF3A1,PRPF19,USP15 |
| 3.433e-03 | -5.67 | ncRNA transcription | biological process | GO:0098781 | 30 | 10 | 16441 | 2138 |
ELL,NIFK,NPM3,SIRT7,ICE2,GTF3C3,POLR1B,ZC3H8,POLR1E,SNAPC4 |
| 3.435e-03 | -5.67 | PDEase_I | pfam domains | PF00233 | 21 | 8 | 16629 | 2165 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 3.438e-03 | -5.67 | 'de novo' IMP biosynthetic process | biological process | GO:0006189 | 6 | 4 | 16441 | 2138 |
ADSL,GART,PPAT,ATIC |
| 3.438e-03 | -5.67 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication | biological process | GO:0086073 | 6 | 4 | 16441 | 2138 |
DSC2,JUP,DSP,DSG2 |
| 3.438e-03 | -5.67 | short-chain fatty acid catabolic process | biological process | GO:0019626 | 6 | 4 | 16441 | 2138 |
MCEE,ACADS,PCCA,MMAA |
| 3.438e-03 | -5.67 | chromosome breakage | biological process | GO:0031052 | 6 | 4 | 16441 | 2138 |
HMGA2,BRCA2,BRCA1,PALB2 |
| 3.438e-03 | -5.67 | programmed DNA elimination | biological process | GO:0031049 | 6 | 4 | 16441 | 2138 |
HMGA2,BRCA2,BRCA1,PALB2 |
| 3.438e-03 | -5.67 | cardiac muscle cell-cardiac muscle cell adhesion | biological process | GO:0086042 | 6 | 4 | 16441 | 2138 |
DSC2,JUP,DSP,DSG2 |
| 3.454e-03 | -5.67 | PH_BEACH | pfam domains | PF14844 | 6 | 4 | 16629 | 2165 |
NBEA,NBEAL1,WDFY3,LYST |
| 3.455e-03 | -5.67 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP | 184 | 37 | 17758 | 2279 |
FBXO45,ZNF292,TRERF1,UBN1,URB2,POLR1A,MRPL10,RNF24,ZFP36L1,IKBIP,INPP1,RPAIN,DDIT4,DOPEY1,RRN3,SUV39H2,ANP32B,SRRM2,SNX29,SAP30,TXLNG,DDX24,MEX3B,DCUN1D5,ENC1,GZF1,EIF4ENIF1,CCNT1,ZNF557,WDR73,APAF1,RUNX1,ZC3H8,POLR1C,ZBTB11,DDIT3,ZBTB24 |
| 3.455e-03 | -5.67 | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | 184 | 37 | 17758 | 2279 |
SEPHS2,TCF12,SEC24D,MFGE8,PDE4B,PPHLN1,HES6,OPA1,COX10,MBNL1,MGA,EXOC1,SIPA1L3,UBR1,TAF3,PPCDC,NDUFA6,RPL22L1,PPA1,HTRA2,TRIM14,FMNL3,EIF4E3,TSPYL4,C2orf76,PTPN12,ARID1A,EIF2A,DHX57,YTHDF2,DDX50,G6PD,SURF1,ZFP90,PPP3CC,ZNF32,PKIB |
| 3.455e-03 | -5.67 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 184 | 37 | 17758 | 2279 |
USP7,BANP,SSH2,ADAM19,RAB11FIP4,XPC,TRAK1,PDE4B,PLOD1,MYH9,BCOR,SH2B3,IFIT5,MAP3K14,CD44,CDC37,MAML3,DBN1,SLC40A1,PXN,COL17A1,SETD1B,GMFB,CUX1,MARCKSL1,MCL1,HSH2D,OASL,METTL22,MFN2,DDAH2,SUPT4H1,G6PD,RUNX1,ITGB4,DHCR7,ZSWIM6 |
| 3.455e-03 | -5.67 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN | 184 | 37 | 17758 | 2279 |
SRM,SLC37A3,SPRED2,PIGM,KLHL18,NLE1,AARS,TMCO6,RAP1A,ARMC6,SLC38A5,MCM5,C12orf76,FTSJ3,NPW,LIMA1,CDK4,TMEM126B,ATOX1,SCFD2,PSMG1,RBM28,GLS,SLC7A1,SLC39A14,TRIB3,TP53BP1,PEMT,DNAJA3,PAM,FNTB,SLC25A11,TRAF3,MED20,TSEN2,ANKS1A,GALE |
| 3.477e-03 | -5.66 | V$USF_Q6_01 | MSigDB lists | V$USF_Q6_01 | 228 | 44 | 17758 | 2279 |
CGN,PRPF38B,MINK1,JUP,ANKRD17,DYM,MKS1,NFX1,ATF7IP,GYG1,MFHAS1,IQGAP2,ATXN7L1,GLYR1,VGF,ACAP3,STC2,DCTN4,NCKIPSD,GTF2H1,IGF2BP1,ETV1,CNOT4,SERBP1,BDNF,NRAS,APEX1,AKAP12,KRTCAP2,BATF3,GTF2A1,HIF1A,HNRNPH3,PER1,KLF4,VPS37B,CSRNP1,HOXA3,MPV17,TRMT2A,SLC16A1,PFDN2,SLC43A1,KAT6A |
| 3.477e-03 | -5.66 | V$ZF5_B | MSigDB lists | V$ZF5_B | 228 | 44 | 17758 | 2279 |
SSH2,DLL4,JUP,NHS,ZIC2,BHLHE40,DNAJC22,PTPRG,SCAF8,SEMA6A,KDM1A,IGF2BP3,METTL16,DST,ZNF827,BRE,HR,SREBF2,PDE10A,ETF1,RAPGEFL1,NLGN3,IGF2BP1,CEP63,FBXL19,ZNF646,ZBTB17,ANAPC13,GON4L,GPHN,ENHO,TLE3,PLCB1,RAB10,MAT2A,POLR3G,MTHFD2,SYNCRIP,SPEN,CDK9,CENPBD1,ANKS1A,PRKAR2A,DDIT3 |
| 3.502e-03 | -5.65 | SEPT9 (septin 9) | protein interactions | 10801 | 46 | 14 | 16036 | 2270 |
VMA21,FN1,SUCLG1,HIF1A,SVIL,FERMT2,VAPB,SUCLG2,SRRM2,FLNB,NEDD4,RAB10,TIMM44,HN1 |
| 3.502e-03 | -5.65 | NELFB (negative elongation factor complex member B) | protein interactions | 25920 | 46 | 14 | 16036 | 2270 |
RFC4,SYNCRIP,EIF3C,BRCA1,EIF2B3,SUPT5H,YBX3,NELFA,ABCF1,FKBP3,MGST1,POLR2A,DENR,IGF2BP3 |
| 3.502e-03 | -5.65 | RYBP (RING1 and YY1 binding protein) | protein interactions | 23429 | 46 | 14 | 16036 | 2270 |
HERC2,ABL1,USP7,PCGF3,E2F4,CSNK2A1,ATF7IP,RNF2,BCOR,BMI1,GABPB2,MGA,CASP10,RING1 |
| 3.502e-03 | -5.65 | CPSF2 (cleavage and polyadenylation specific factor 2) | protein interactions | 53981 | 46 | 14 | 16036 | 2270 |
SMARCAD1,RRAGA,SMARCD3,SMARCA4,GTF3C3,POLE3,CPSF3,FIP1L1,WDR33,SUPT5H,SYMPK,CDC73,POLR2A,CLK2 |
| 3.520e-03 | -5.65 | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 178 | 36 | 17758 | 2279 |
ACTG1,CAMK1,MAP1S,LETMD1,SLC29A1,INPP1,C15orf57,ETFB,TADA3,BRE,ERI1,C12orf76,RDX,RAN,PNPLA3,FUT11,RABEPK,FAM127A,KDM5B,EYA3,LDHA,GPNMB,CYB5B,TMEM187,CAMK2D,TRIB3,ASTN2,PAM,SQLE,EIF2S1,EME1,CCNB1IP1,TXN2,ADK,PPIL3,ZNF589 |
| 3.535e-03 | -5.64 | LOPEZ_MBD_TARGETS | MSigDB lists | LOPEZ_MBD_TARGETS | 900 | 143 | 17758 | 2279 |
PTP4A1,MYCBP2,CUL4A,PRKCSH,SEC16A,AMBRA1,RAP1A,ECM1,SREBF2,S100A10,ATP5G2,HYAL1,RAN,FUT11,CDC37,SF3A1,ATF4,UPP1,MED27,ABCC2,SON,ARPC3,DOT1L,DDX3X,HPRT1,TRRAP,SSU72,INSIG1,NSMCE1,E2F4,SEMA3C,PPP3CC,FIP1L1,TXN2,FN1,FAM189B,EVPL,XPO7,PDCD5,CHD5,PITPNM1,RSPRY1,SUB1,EIF2S2,MYC,PPIL2,CCDC88C,ATP6V0D1,IFRD1,TRAPPC9,CRADD,EPS15L1,IDH3G,RAP1B,PSMA1,WWC1,SMARCD3,EIF2A,SUPT5H,SRA1,KPNA1,NSF,TRAP1,PPP1R12B,IFITM2,MAP2K5,MMRN2,SLC2A1,CD99L2,UBTD2,RPAIN,FDX1,RING1,KDM1A,NDUFB3,BCAS2,SHC1,MRPS27,CORO1A,SERPINH1,VCL,GARS,EVL,RFC3,SSFA2,KRT7,TUBA1A,EIF3J,SFXN4,PCMT1,MRRF,MED16,C1orf174,RAB10,MAT2A,EIF3H,FGFR1,WARS,ZBTB25,ITGA2,ATG7,FTSJ1,MUTYH,BRAF,MINK1,SUPT6H,PPHLN1,APRT,AKT1S1,TGFB2,NDUFV1,ANXA7,PMPCA,ANXA5,ERRFI1,ACTR3B,SPTAN1,RPS6KB2,APEX1,CRIM1,FOXN3,WDR18,LDHA,METTL23,ADSL,PACS1,RANGAP1,MEN1,ECH1,ANXA1,TPD52L2,PXDN,BAZ2B,DSC2,ZBTB8OS,SET,FNTB,USP20,EIF2S1,BMP4,STK4,LRRC41,SLC43A1 |
| 3.546e-03 | -5.64 | LIN28A (lin-28 homolog A (C. elegans)) | protein interactions | 79727 | 86 | 22 | 16036 | 2270 |
SNU13,DDX41,NOL6,DKC1,RBM28,HNRNPA3,DHX57,IGF2BP3,DOT1L,KRI1,POP1,PWP1,TSR1,DDX50,IFIT5,NCBP2,NOC3L,FBL,LARP4B,ZBTB11,SRP14,PRPF19 |
| 3.546e-03 | -5.64 | NOL12 (nucleolar protein 12) | protein interactions | 79159 | 86 | 22 | 16036 | 2270 |
NIFK,LIN28B,DDX24,CDK4,MINA,NAT10,MRPS10,DKC1,RBM19,NLE1,RBM28,DHX57,PUM3,MRPS11,KRI1,DDX50,MRPS27,PAK1IP1,DDX31,DDX10,FTSJ3,ZBTB24 |
| 3.548e-03 | -5.64 | CELL_CYCLE_GO_0007049 | MSigDB lists | CELL_CYCLE_GO_0007049 | 312 | 57 | 17758 | 2279 |
DCTN3,BCCIP,TTN,CUL4A,TAF1,XPC,PAFAH1B1,KHDRBS1,DBF4,TUBE1,TGFB2,MAD2L2,ABL1,ASNS,NEK6,MYC,TRIAP1,XRCC2,ANAPC11,ANAPC10,PDS5B,GTF2H1,TIMELESS,ATRIP,RAN,MSH4,PRMT5,CDK6,CDC37,ZBTB17,PPP1R9B,KRT7,POLA1,CDK4,FOXN3,KIF15,TOP3A,TBRG4,MCM2,FOXC1,MFN2,RAD54B,SMAD3,RBBP8,BRCA2,CDC16,GADD45A,CCNT1,CUL2,TBX3,RAD51B,PAM,ATM,BMP4,NOLC1,ZAK,ANAPC4 |
| 3.554e-03 | -5.64 | human chr12q24.21 | chromosome location | human chr12q24.21 | 4 | 3 | 26250 | 2590 |
MED13L,RBM19,TBX3 |
| 3.558e-03 | -5.64 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication | molecular function | GO:0086083 | 6 | 4 | 16491 | 2164 |
DSC2,JUP,DSP,DSG2 |
| 3.561e-03 | -5.64 | CUL7 (cullin 7) | protein interactions | 9820 | 640 | 115 | 16036 | 2270 |
SART1,CUL7,PRDX6,DDX18,ATP6V1A,PRKCSH,ACTR3,OLA1,NAT10,RSL1D1,CSNK2A1,TUBB6,NUP43,SAFB2,NUP160,PELP1,HNRNPA3,PABPC4,FLNB,AMBRA1,NOP56,CAD,RAN,SERPINH1,SRRM2,LONP1,TIMM50,SF3A1,TMPO,PRPF19,WDR36,SLC3A2,LIMA1,GNL3,RAB7A,HSPA5,PCMT1,PNN,DKC1,SON,DSP,NUP214,RAB10,STOML2,ARPC3,PES1,UBTF,DDX3X,RANBP2,HPRT1,AHNAK,HNRNPR,LUC7L3,FUS,HEATR1,MDN1,ANXA2,FIP1L1,NOLC1,PDCD11,WDR75,NIFK,TTN,JUP,SUPT6H,KHDRBS1,SIRT7,HSD17B10,SF3A3,APRT,PHGDH,HIST2H2AB,ETFB,IGF2BP3,DDX56,SNW1,GART,ATIC,DSG2,ZNF326,ANXA5,HIST2H3D,SHMT2,IGF2BP1,FBL,PRMT5,PABPC1,NUDC,TOP1,NIPSNAP1,MTHFD1,PSPC1,WDR18,LDHA,RANGAP1,MARS,IMPDH2,HIST1H4J,SUPT5H,NOP58,TARS,POLR2A,UBC,RPA1,ANXA1,DYNC1H1,EPRS,DDX50,MYBBP1A,SYNCRIP,PDLIM1,TRAP1,SPEN,HNRNPH3,DHCR7 |
| 3.562e-03 | -5.64 | serine/threonine protein kinase complex | cellular component | GO:1902554 | 67 | 17 | 17570 | 2233 |
GTF2H3,BRD4,MAP3K13,RB1CC1,PRKAB2,KDM5A,TGFBR2,ERC1,SNW1,PHKA1,CCNT1,DNAJA3,CDK9,IKBKB,GTF2H1,PRKAR2A,PRKACB |
| 3.565e-03 | -5.64 | prostate-adenoma | COSMIC cancer mutations | prostate-adenoma | 1691 | 253 | 17775 | 2278 |
MYCBP2,PHF3,ATRX,KIF5A,DCP1B,NAT10,TRPM6,CHAC1,SIRT2,PRKCA,LPAR3,LPIN1,AMBRA1,ZNF37A,DST,ANAPC1,ZFHX3,JAZF1,MYH3,TRIML2,RNF111,GPATCH1,JOSD1,CHD2,POLR3B,KDM5C,HRG,AVEN,TRIM14,ZNF646,PTPRK,DSC3,DEAF1,KLHL23,SKIV2L2,KATNAL1,GPCPD1,ABCC2,BRCA1,KMT2C,SON,KIF16B,PEX1,SPOP,CHAF1A,BSN,SKIL,PAF1,GEMIN5,TCF7L1,BRCA2,TRRAP,ZNF266,TP53BP1,DNAJC1,CHD3,CCDC146,RAD51B,CSMD3,DNAH2,GALNT10,COPS6,SLC25A26,ZMAT3,NMD3,HERC2,OXNAD1,STX8,CELSR1,VTA1,TRIO,NHS,DLGAP4,TATDN3,ALG8,PCSK7,RSF1,PHGDH,CD226,IGF2BP3,TECTA,RNF40,DDX56,SIPA1L3,TSPAN2,COPS3,PIGG,MED24,GTF3C3,ZNF518B,ZCCHC7,PPA1,SERBP1,ANGPT2,LRRC20,SCAF11,NAA38,RANBP6,COL17A1,LAMC1,SYNGAP1,ALG6,KCNQ3,TSTA3,IFT43,CORIN,SYT1,AGAP1,PGD,IRS1,PWP1,DYNC1H1,LRP1B,UBAP2,ATAD5,HIF1A,FSCN1,VCAN,ZZEF1,DNAH17,ZCCHC6,IQSEC2,TBCK,SH3PXD2A,COG5,SPRED2,PTCD2,RAB11FIP4,ABCA3,SYT17,ASH1L,TRPM2,BIRC6,NPAS2,ATP6V1A,CELSR3,SLC5A5,HFM1,TMEM183A,GPR143,PIGH,OLA1,C1QTNF7,MYH9,NECAP1,SSBP2,NUP43,ST3GAL6,DENND3,TNKS1BP1,SAFB2,PPP1R9A,SLC39A1,FLNB,PLXNB1,PDE3A,NRF1,DECR1,MPHOSPH10,BRE,SHC1,VGF,MMP14,AKNAD1,VCL,KMT2A,ZC3H3,NAA35,MCEE,C18orf21,ARHGAP17,PHLDB2,GON4L,NPM3,MANBAL,PCMT1,PREX1,POU2F1,ATP6V0A1,KCNH3,DSP,UBR4,HSD3B7,USP36,PDE8B,SMAD3,CDC16,ALAD,CAMKMT,POLR3E,ATG7,WDR7,TRAF3,NFASC,MDN1,EIF2B3,ZBTB11,LAMA5,TSPAN5,MAPT,PARD3,LRCH1,DYM,CMTM8,MON2,BMP6,MAN1A1,POLR3D,RGS17,SACS,NEBL,SEC24C,LRP2BP,PVRL3,UPF2,DDX31,TTC17,LARP4B,SAMD4A,C12orf4,SPTAN1,DDHD1,TMC7,DNMBP,ADAMTSL3,APEX1,LSM12,WDFY3,CLYBL,FZD3,ANKMY2,ZMYM5,TOP3A,TBRG4,RSBN1,PDE2A,PIK3CB,SLC23A2,RPA1,YIF1A,SRCAP,IREB2,GPC2,TBX3,ORC5,ATM,MYOM2,PSAP,GPAM,RPS6KC1,IGBP1,MMP16,NIT1 |
| 3.568e-03 | -5.64 | fatty acid beta-oxidation | biological process | GO:0006635 | 55 | 15 | 16441 | 2138 |
MCEE,ACADS,DECR1,ETFDH,PEX7,SESN2,ACOX1,PCCA,BDH2,CPT1A,ACOXL,MMAA,ECH1,ETFB,CPT1C |
| 3.570e-03 | -5.64 | KIM_GERMINAL_CENTER_T_HELPER_UP | MSigDB lists | KIM_GERMINAL_CENTER_T_HELPER_UP | 61 | 16 | 17758 | 2279 |
PRPF38B,STAMBP,ACTR3,KSR2,PHACTR2,UBTD2,MAN1A1,AMPD3,HPRT1,DNAJB6,ANKRD11,HIBCH,ZMAT3,PTPN14,PRKACB,LPP |
| 3.572e-03 | -5.63 | cell-substrate adherens junction | cellular component | GO:0005924 | 395 | 69 | 17570 | 2233 |
ARHGAP26,ACTG1,ACTR3,RPS29,DDR2,MYH9,CD99L2,ENAH,GIT2,HSPA1A,FLNB,DST,RPS16,PPFIBP1,MMP14,VCL,FLNC,PHLDB2,EVL,LIMA1,HSPA5,AKAP12,VIM,CAV1,NUP214,RAB10,ARPC3,RHOU,AHNAK,MISP,ITGA2,DPP4,ADAM9,NFASC,NRP1,LPP,EFNB2,JUP,TRIP6,LAMTOR3,NHS,MCAM,ANXA5,RDX,CD44,PABPC1,PNMA1,CAV2,PXN,TPM4,ASAP3,PTPN12,ATAT1,LIG4,FERMT2,PTK2,PALLD,PEAK1,HSPA1B,ANXA1,CAT,PDLIM1,SRP68,FAT1,SNAP23,ADGRE5,CASS4,SVIL,PRKAR2A |
| 3.578e-03 | -5.63 | CTBP1 (C-terminal binding protein 1) | protein interactions | 1487 | 151 | 34 | 16036 | 2270 |
NCOR2,NOL4L,ZNF516,BCOR,FOXP1,KDM1A,TERF2IP,FKBP1A,ATIC,WIZ,ZEB1,RNF111,SERPINH1,NRIP1,KMT2A,CARM1,TERF2,SOBP,RREB1,EHMT1,PNN,BRCA1,PLCB1,TCF7L2,RBBP8,EHMT2,IKZF4,CHD3,KLF4,SPEN,HIC2,BCAS3,RUNX1,TBL1X |
| 3.580e-03 | -5.63 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | 172 | 35 | 17758 | 2279 |
KCTD7,BANP,ITPRIP,UBTD2,URB1,SFI1,ABL2,AMPD3,TAF3,SCN1B,PYCRL,PAK1IP1,TNPO3,JOSD1,RDX,DDX31,TSPAN14,MGLL,YARS,ACSL5,SESN2,GARS,SLC3A2,TRIM13,CRADD,UPP1,GNL3,IMPDH2,ABCF1,PRPF40B,SPAG9,ZNF81,H2AFX,MB21D2,IPO4 |
| 3.619e-03 | -5.62 | V$MYCMAX_02 | MSigDB lists | V$MYCMAX_02 | 254 | 48 | 17758 | 2279 |
CHST11,ANKRD17,TNFRSF21,TMEM109,ATF7IP,BCOR,TGFB2,TIMM10,MBNL1,PABPC4,IQGAP2,PRKCH,CAD,RSPRY1,FAM192A,VGF,METTL8,IGF2BP1,FBL,ETV1,SERBP1,ANGPT2,TOP1,MAML3,MTHFD1,RTN4RL2,PPP1R9B,TXLNG,ARRDC3,JMJD1C,TOP3A,GRHL3,SATB2,UBR4,USP36,MAT2A,SYNCRIP,HIF1A,POLR3E,HOXA3,CSMD3,UMPS,RBM26,FKBP5,NOLC1,RAB30,ATXN7L2,USP15 |
| 3.633e-03 | -5.62 | AFF1 (AF4/FMR2 family, member 1) | protein interactions | 4299 | 28 | 10 | 16036 | 2270 |
NSD1,BRD4,CCNT1,CDK9,KMT2A,CARM1,POLR2A,MLLT10,DOT1L,NT5E |
| 3.633e-03 | -5.62 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | 197 | 39 | 17758 | 2279 |
ADAM19,FAM207A,DYM,ID2,DPM3,BHLHE40,ST3GAL6,AARS,EEA1,ETFB,LPIN1,IQGAP2,SHC1,S100A10,MBD2,CLDND1,CD44,ITGAX,ERRFI1,PRF1,LYPLA2,CDK4,LGALS1,MAP7D1,PACS1,KRTCAP2,ODC1,KLF6,UBC,ANXA1,AHNAK,KLF4,RNF138,PAM,PPP3CC,ANXA2,NRP1,NFKBIB,ZMAT3 |
| 3.641e-03 | -5.62 | MRNA_PROCESSING_GO_0006397 | MSigDB lists | MRNA_PROCESSING_GO_0006397 | 72 | 18 | 17758 | 2279 |
SCAF11,PRPF31,RNMT,SFSWAP,KHDRBS1,TRA2A,SF3A3,SPOP,GEMIN5,SNW1,SRSF2,PHF5A,HNRNPR,CELF1,CPSF3,PABPC1,SRPK2,SF3A1 |
| 3.650e-03 | -5.61 | XRN1 (5'-3' exoribonuclease 1) | protein interactions | 54464 | 81 | 21 | 16036 | 2270 |
SKIV2L,FADS1,DDX24,SKIV2L2,DCP1B,SIRT7,SNHG1,LDHA,MLH1,PABPC4,RPA1,SYNCRIP,ATP5G2,MYC,ADGRE5,UPF2,HEATR1,CENPBD1,PRADC1,BMI1,SRRM2 |
| 3.662e-03 | -5.61 | AAA_5 | pfam domains | PF07728 | 13 | 6 | 16629 | 2165 |
DYNC1H1,DNAH2,DYNC2H1,MDN1,DNAH1,VWA8 |
| 3.675e-03 | -5.61 | negative regulation of histone modification | biological process | GO:0031057 | 35 | 11 | 16441 | 2138 |
SUPT6H,KDM5A,SET,ATG7,BCOR,BRCA1,UBR5,KDM1A,SKI,SMARCB1,SNCA |
| 3.677e-03 | -5.61 | ARID1A (AT rich interactive domain 1A (SWI-like)) | protein interactions | 8289 | 51 | 15 | 16036 | 2270 |
SMAD3,CHD7,DPF3,SMARCC1,ADNP,DPF2,SIRT7,CUL2,SMARCD3,SMARCA4,SHMT2,ARID1B,CARM1,NEDD4,SMARCB1 |
| 3.677e-03 | -5.61 | MAP3K3 (mitogen-activated protein kinase kinase kinase 3) | protein interactions | 4215 | 51 | 15 | 16036 | 2270 |
SPAG9,MAP2K5,COPS5,IKBKB,RIPK1,RCAN1,BRCA1,FUS,PFDN2,BIRC2,MAP2K4,MAP2K3,NEDD4,TOM1L1,CDC37 |
| 3.677e-03 | -5.61 | FANCD2 (Fanconi anemia complementation group D2) | protein interactions | 2177 | 51 | 15 | 16036 | 2270 |
RBBP8,BRCA2,KPNA1,RAD18,MYC,TNFRSF1A,H2AFX,FAN1,ATM,BRCA1,MLH1,MEN1,FOXO3,UBC,IPO4 |
| 3.681e-03 | -5.60 | chromatin disassembly | biological process | GO:0031498 | 17 | 7 | 16441 | 2138 |
SMARCA4,SMARCD3,ARID1A,SMARCC1,ARID2,SET,SMARCB1 |
| 3.681e-03 | -5.60 | nucleosome disassembly | biological process | GO:0006337 | 17 | 7 | 16441 | 2138 |
SMARCA4,SMARCD3,ARID1A,SMARCC1,ARID2,SET,SMARCB1 |
| 3.681e-03 | -5.60 | protein-DNA complex disassembly | biological process | GO:0032986 | 17 | 7 | 16441 | 2138 |
SMARCA4,SMARCD3,ARID1A,SMARCC1,ARID2,SET,SMARCB1 |
| 3.682e-03 | -5.60 | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | 733 | 119 | 17758 | 2279 |
CHMP2A,ABCA3,PCNT,SUCLG1,ACTG1,KIAA0232,RPS29,C16orf45,NDUFB5,SMARCA4,NECAP1,AARS,KDM1A,NDUFB3,RTN1,FARSA,RPS16,ASNS,IDI1,ACD,PPID,CLCN6,VPS52,JOSD1,CORO1A,RAN,YARS,PTPRK,DBN1,DEAF1,SLC3A2,FAM127A,TUBA1A,ATG9A,NARS,STAMBP,ITPA,ATOX1,LGALS1,MARCKSL1,SUMO3,VIM,ST3GAL5,SERP1,CLNS1A,SH3GL1,ATP5D,BSN,GNAI1,GLS,PES1,CDC16,SUPT4H1,DCXR,COPS5,ARL4A,WDR7,PAM,AHNAK2,SLC25A11,USP11,BMI1,AP2S1,SPOCK2,BAG1,DCTN3,SARS,AUH,SCAMP3,CA11,CAMK1,DPF2,FAN1,PRAF2,SLC25A12,ARFIP2,SSR4,CLINT1,REEP5,ETFB,NDUFS7,FKBP1A,TTC1,NDUFV1,SCN1B,VPS72,CLDND1,ANP32B,ERI3,ATP6V0D1,TOMM34,NUDC,SPTAN1,NIPSNAP1,HMGCR,FAM98A,ANAPC13,RAP1GAP2,SULT4A1,RNH1,SMARCD3,RABAC1,IMPDH2,PDE2A,TRIM37,ECH1,NCDN,DYNC1H1,RPL28,NSF,STX1A,TRAP1,FDPS,RRAGA,PSAP,DHCR7,SRP14,CORO2B,DDIT3 |
| 3.684e-03 | -5.60 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | 160 | 33 | 17758 | 2279 |
TNIK,JUP,NF1,SMG7,SMARCA4,TRIM22,SPATS2L,ABL1,GART,PPID,CEP290,GLYR1,C16orf58,MED24,NAA35,TRIM14,SCAF11,DDX24,PARP2,WDHD1,PHACTR2,OASL,SON,DDX60,EIF5B,ST3GAL5,ISG15,RPL28,SYNCRIP,GLG1,SLC25A11,IFITM2,SMG1 |
| 3.690e-03 | -5.60 | maintenance of cell number | biological process | GO:0098727 | 146 | 31 | 16441 | 2138 |
BRAF,CUL4A,FOXO1,FGF2,PRDM16,MED27,PBX1,LIG4,SOX4,FOXO3,CDC73,FGFR1,POLR2A,TCF7L2,SKI,PAF1,TCF7L1,JAG1,EIF4ENIF1,ZNF358,KLF4,VPS72,MED15,TBX3,CTR9,MED24,RBPJ,IGF2BP1,SETD6,DIS3L2,KAT6A |
| 3.717e-03 | -5.59 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | 191 | 38 | 17758 | 2279 |
AK2,ACTG1,PSTPIP2,ID2,RTN4,RCAN1,SPATS2L,BHLHE40,ST3GAL6,CSTA,RTN1,FKBP1A,SH2B3,DST,S100A10,ATG3,ITGAX,VCL,GNG5,CSGALNACT2,PEA15,RAB7A,TBXAS1,LDHA,LGALS1,RNH1,VIM,MCL1,COTL1,IL6R,ANXA1,CAT,AHNAK,KLF4,APAF1,RNF130,PSAP,AP2S1 |
| 3.717e-03 | -5.59 | GSE22886_TH1_VS_TH2_12H_ACT_UP | MSigDB lists | GSE22886_TH1_VS_TH2_12H_ACT_UP | 191 | 38 | 17758 | 2279 |
TBKBP1,SPRED2,TRIP6,GPR143,SMAD7,NFX1,TBCCD1,ZFP36L1,RCAN1,IP6K2,CD226,PELP1,NRF1,FGGY,PMPCA,NBEA,ANXA5,CCDC40,RDX,FBXO31,CCDC88C,DMRT1,PNMA1,CPSF3L,DBN1,PEA15,ELOVL6,C11orf80,MINA,KPNA1,STX18,SRD5A3,PQBP1,SNX24,PAM,TRAF3,SLC43A1,P2RY11 |
| 3.717e-03 | -5.59 | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | 191 | 38 | 17758 | 2279 |
CHST11,DROSHA,ZBTB37,C16orf52,CDC73,ETFB,NEDD4,MAD2L2,IGF2BP3,KCTD11,PUS3,LYPLAL1,ZSWIM7,CEP290,DNAJB6,DSG2,NT5M,RANBP6,AP4S1,IFT43,EIF3J,MTIF2,USP42,MED27,DCUN1D5,SRA1,PLIN2,MGAT2,TAF2,TMCO1,HSDL2,MPP7,COQ9,ARL4A,NSMCE2,TAF12,COPS6,BMI1 |
| 3.731e-03 | -5.59 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | MSigDB lists | REACTOME_PERK_REGULATED_GENE_EXPRESSION | 26 | 9 | 17758 | 2279 |
EXOSC2,ASNS,ATF4,HSPA5,EIF2S1,EXOSC4,PARN,DDIT3,HERPUD1 |
| 3.741e-03 | -5.59 | TGF-beta Receptor Signaling Pathway | WikiPathways | WP366 | 151 | 31 | 4455 | 564 |
FOXO1,CDK4,SMAD7,PPP2R2A,CAV1,TGFB2,NUP214,TGFBR2,FOXO3,MAP2K3,SKI,SMAD3,VDR,SKIL,FKBP1A,SNW1,CAMK2D,ANAPC1,CDC16,TRAP1,COPS5,E2F4,MYC,ANAPC10,ZEB1,CD44,PRKAR2A,CDK6,ANAPC4,PARD3,MEF2C |
| 3.742e-03 | -5.59 | KPNB1 (karyopherin (importin) beta 1) | protein interactions | 3837 | 157 | 35 | 16036 | 2270 |
CUL7,FN1,SIRT7,FAN1,MLH1,CSNK1A1,UBR5,NOP56,PTPN2,PRKD3,SREBF2,TAF3,MYC,RAN,NRIP1,LYST,TERF2,RANBP6,EXOSC2,TUBA1A,HSPA5,UBC,FGFR1,EXO1,DYRK1B,SMAD3,RANBP2,KPNA1,KPNA3,CHD3,TP53BP1,COPS5,CUL2,FUS,IPO4 |
| 3.746e-03 | -5.59 | LIU_PROSTATE_CANCER_UP | MSigDB lists | LIU_PROSTATE_CANCER_UP | 89 | 21 | 17758 | 2279 |
CAMKK2,ABCC4,MARCKSL1,APRT,SOX4,NLE1,BZW2,SERP1,PPP1R9A,PYCR1,SRPRB,SAMD5,MTHFD2,ENTPD5,TMEM161A,SH3RF1,FNIP2,GMDS,PDLIM5,RPL22L1,SLC43A1 |
| 3.747e-03 | -5.59 | ARM | smart domains | SM00185 | 29 | 10 | 9131 | 1249 |
ARMC4,KPNA1,KPNA3,ARMC6,JUP,ARMC5,RAP1GDS1,ARMC3,SPAG6,TMCO6 |
| 3.750e-03 | -5.59 | SRXN1 (sulfiredoxin 1) | protein interactions | 140809 | 37 | 12 | 16036 | 2270 |
TTC1,TOM1L2,TRIP6,THADA,UCHL5,TLE3,TPM4,ZRANB2,TUBB6,TPM1,AHCYL1,IGBP1 |
| 3.775e-03 | -5.58 | embryonic cranial skeleton morphogenesis | biological process | GO:0048701 | 45 | 13 | 16441 | 2138 |
SMAD3,CHST11,RDH10,SETD2,MMP14,BMP4,MTHFD1L,DLX2,TGFBR2,MMP16,SLC39A1,MTHFD1,MEF2C |
| 3.778e-03 | -5.58 | negative regulation of chromosome segregation | biological process | GO:0051985 | 40 | 12 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 3.778e-03 | -5.58 | negative regulation of sister chromatid segregation | biological process | GO:0033046 | 40 | 12 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 3.778e-03 | -5.58 | telomere maintenance via telomere lengthening | biological process | GO:0010833 | 40 | 12 | 16441 | 2138 |
TERF2IP,RFC4,RFC3,POLE2,PRIM2,APEX1,POLA1,DKC1,TNKS1BP1,CTC1,TERF2,RPA1 |
| 3.778e-03 | -5.58 | spindle checkpoint | biological process | GO:0031577 | 40 | 12 | 16441 | 2138 |
KLHL22,ANAPC1,CDC16,ANAPC11,ANAPC10,TEX14,MAD1L1,ATM,CSNK2A1,MAD2L2,UBE2E1,ANAPC4 |
| 3.778e-03 | -5.58 | head morphogenesis | biological process | GO:0060323 | 40 | 12 | 16441 | 2138 |
MSX1,BRAF,ARID5B,MYH3,CSRNP1,ANKRD11,TGFB2,FLVCR1,TCF7L2,SKI,DKK1,KAT6A |
| 3.783e-03 | -5.58 | PNKP (polynucleotide kinase 3'-phosphatase) | protein interactions | 11284 | 56 | 16 | 16036 | 2270 |
POLB,LIG4,SLC25A12,NOL3,TRIM37,KDM1A,SBDS,RPA1,AGTPBP1,MCM5,GEMIN4,XRCC4,NOLC1,C18orf25,MID1,NOM1 |
| 3.783e-03 | -5.58 | MCRS1 (microspherule protein 1) | protein interactions | 10445 | 56 | 16 | 16036 | 2270 |
KAT8,CCDC53,LIG4,BRCA1,TRIM37,UBR5,UBR4,KDM1A,UBTF,PHC2,KIAA1958,UCHL5,CCDC85B,NFRKB,PRMT5,FBL |
| 3.785e-03 | -5.58 | Galactose-bd-like | interpro domains | IPR008979 | 78 | 19 | 18293 | 2341 |
HERC2,MYCBP2,FBXO17,CUL7,LAMC1,CNTNAP3,MFGE8,HECTD3,DDR2,PCSK7,BTBD9,LAMA2,DCBLD2,ZZEF1,ANAPC10,NRP1,CNTNAP3B,NR2C2AP,PCSK6 |
| 3.788e-03 | -5.58 | RB_P130_DN.V1_DN | MSigDB lists | RB_P130_DN.V1_DN | 130 | 28 | 17758 | 2279 |
VOPP1,PRPF38B,TXLNG,KDM5B,EIF3J,GPCPD1,SLC2A1,TMEM123,WDR26,ARRDC4,DSP,EVI5,HSPA1A,HSPA1B,KIF16B,ATP9B,SPOP,DDX3X,VDR,IDI1,EIF2S2,GADD45A,DNAJC1,SEC24C,RRAGA,HK2,CLU,TOMM34 |
| 3.793e-03 | -5.57 | CCATCCA,MIR-432 | MSigDB lists | CCATCCA,MIR-432 | 56 | 15 | 17758 | 2279 |
TOX4,PCGF3,CHD9,GPM6A,RBCK1,ARID2,IDH3G,KLHL18,RSBN1,IGF2BP2,SOX4,LARP4B,CALN1,RAB10,CLK2 |
| 3.794e-03 | -5.57 | RNA 3'-end processing | biological process | GO:0031123 | 88 | 21 | 16441 | 2138 |
EXOSC2,LIN28B,DKC1,PABPC1L,SYMPK,CDC73,PAF1,SRSF2,SSU72,ERI1,ZCCHC6,NCBP2,EXOSC4,WDR33,ERI3,CPSF3,AHCYL1,FBL,ZC3H3,PABPC1,LSM10 |
| 3.797e-03 | -5.57 | V$HEN1_01 | MSigDB lists | V$HEN1_01 | 185 | 37 | 17758 | 2279 |
TCF12,DLL4,TRERF1,PAX2,VPS45,ARFIP2,CD99L2,CLINT1,FOXP1,KDM2A,JOSD1,NLGN3,MGLL,CDK6,PABPC1,SPAG6,MOSPD1,BDNF,DPF3,ENHO,ANK2,JMJD1C,KCNMA1,WBSCR22,KRTCAP2,ONECUT2,HSD3B7,YTHDF2,INF2,ADNP,HIF1A,SIX5,ARL4A,TBX3,SNX24,BMP4,BRSK2 |
| 3.797e-03 | -5.57 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_UP | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_UP | 185 | 37 | 17758 | 2279 |
BCCIP,FBXO45,SSH2,NDUFA5,C17orf80,URB2,PRKAB2,KIAA0232,HSD17B10,CIAPIN1,GATC,SUV39H2,YLPM1,MRPS27,POLR3B,CPSF3L,FAM98A,IFNGR2,LIMA1,CDK4,EHMT1,ATXN1,MEX3B,ENC1,SLC9A5,ZNF251,MFN2,FBXO21,EIF4ENIF1,COQ9,TAF4,UMPS,TRAF3,FIS1,RUNX1,POLR1C,BLMH |
| 3.797e-03 | -5.57 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 185 | 37 | 17758 | 2279 |
MCM6,ACTG1,WDR74,CLK1,B4GALT5,NAT10,MED13L,KLHL18,BHLHE40,FOXO3,MBNL1,RIOK2,SH2B3,ZBED2,IKZF5,KDM2A,SLC38A2,UTS2,LPCAT1,SLC38A6,PDK1,ZNF654,MARCKSL1,MAPK1IP1L,AKAP13,SUPT5H,MAT2A,ZBTB25,SLC23A2,SLC39A14,FBXO21,KPNA1,MTHFD2,INSIG1,SPEN,H2AFX,LPP |
| 3.801e-03 | -5.57 | SON (SON DNA binding protein) | protein interactions | 6651 | 71 | 19 | 16036 | 2270 |
SNU13,CUL7,TRIP6,NDUFAF2,TCF3,SIRT7,TFPI,NFIA,PHGDH,SMARCB1,BUD31,RNF2,RAN,BMI1,SRRM2,HNRNPM,SRPK2,PRPF19,CLK2 |
| 3.801e-03 | -5.57 | RAD50 (RAD50 homolog, double strand break repair protein) | protein interactions | 10111 | 71 | 19 | 16036 | 2270 |
CUL7,SIRT6,ATRX,SMARCAD1,SIRT7,USP42,BRCA1,MLH1,RPA1,NOP56,TERF2IP,RBBP8,HNRNPR,MCM5,H2AFX,ATM,RNF2,USP11,TERF2 |
| 3.813e-03 | -5.57 | poly(U) RNA binding | molecular function | GO:0008266 | 13 | 6 | 16491 | 2164 |
ATXN1,MSI2,PABPC1,KHDRBS1,PABPC4,DIS3L2 |
| 3.813e-03 | -5.57 | ACTL6A (actin-like 6A) | protein interactions | 86 | 97 | 24 | 16036 | 2270 |
EP400,DPF3,SMARCAD1,DPF2,SMARCA4,SMARCD3,ARID1A,ARID1B,POLR2A,UBC,SMARCB1,TRRAP,SMARCC1,MYC,CDK9,UCHL5,BANF1,RELB,ZRANB2,SHMT2,ETF1,NFRKB,BMI1,SF3A1 |
| 3.813e-03 | -5.57 | CBX8 (chromobox homolog 8) | protein interactions | 57332 | 97 | 24 | 16036 | 2270 |
USP7,PCGF3,NIFK,HMBOX1,CCDC57,TFCP2,SETD2,CSNK2A1,IGF2BP2,RING1,IGF2BP3,PHC2,KRI1,TSR1,SPAG9,UBR1,RNF2,IGF2BP1,FBL,USP11,YBX3,KMT2A,BMI1,PDCD11 |
| 3.813e-03 | -5.57 | EEF1D (eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)) | protein interactions | 1936 | 97 | 24 | 16036 | 2270 |
FLNC,GARS,CUL7,FN1,FRA10AC1,SF3A3,CSNK2A1,RTN4,CAMSAP2,VARS,VIM,FOSL2,PRKCA,SUPT5H,ECH1,NR2F1,FARSA,EPRS,ARHGAP21,AHNAK,CUL2,ATG7,RNF2,SRRM2 |
| 3.855e-03 | -5.56 | lipid particle | cellular component | GO:0005811 | 62 | 16 | 17570 | 2233 |
LDAH,SIGMAR1,LPCAT2,RAB7A,RAP1B,ATG2B,CAV1,PITPNM1,GBF1,PLIN2,LSS,TRAP1,FAAH2,ANXA2,LPCAT1,PRPF19 |
| 3.858e-03 | -5.56 | positive regulation of biological process | biological process | GO:0048518 | 5310 | 745 | 16441 | 2138 |
PTP4A1,ARHGAP26,THOC5,ACTG1,DCP1B,CACNA1H,SBF2,CSPP1,HLTF,CCNL2,ABHD6,SYNJ1,LPAR3,NOS1AP,AMBRA1,SKI,TOM1L1,NEK6,SREBF2,ZFHX3,PMAIP1,RABGAP1L,WIZ,ZNF148,FNIP2,HRG,FXN,CDK6,HMBOX1,NRAS,WLS,PTPRM,GNL3,NFIA,AKAP12,C5AR1,MCL1,SHISA5,DCUN1D5,SLC50A1,STOML2,DDX3X,BRCA2,SUPT4H1,RAD18,FIS1,DIRAS1,RUNX1,TPM1,VASH2,P2RY11,MEF2C,BANP,HERC2,EPM2AIP1,TRIP6,SLK,KHDRBS1,TRIO,SIRT7,PIK3R4,RSF1,PDCD7,CDC73,SLC1A1,ABCA7,SH2B3,CHN1,RBM20,CNST,UBE3A,APLF,CACNB2,MED24,ANP32B,PRMT5,MAP3K12,PABPC1,ANGPT2,MYB,HMGCR,PEA15,GTF2H3,BDNF,WDR61,STAG1,MYO10,RB1CC1,PRDM16,ARID5B,RYR2,ATAT1,SMARCD3,SNAP25,ARRDC4,EVI5,CPT1A,TRIM37,ONECUT2,ABCF1,IRS1,TASP1,KPNA1,RPL28,FGFBP1,CDK9,CNOT6,ARHGAP10,SGSM3,SPRED2,DNM3,MAP2K5,ZNF516,TRERF1,PAFAH1B1,NPAS2,ACTR3,DDR2,MYH9,AGAP6,STAM,UBL5,HSPA1A,SPG21,ABCA12,ACD,TBC1D22A,WAC,MMP14,ZC3H3,LSM10,DENND1A,PERP,LYST,KMT2D,STAMBP,LGALS1,ARHGEF10,MEF2D,FGFR1,TAF2,FBXL5,HLA-DMA,ARHGAP21,CDC16,NSMCE2,PEMT,HIPK2,POLR3E,HOXA3,RPS6KB1,BRCC3,MAPT,HMGA2,SERINC5,SHQ1,INSIG2,ID2,GAS6,TRIM22,IP6K2,RNASEH2B,TGFB2,PSMF1,TADA3,SNW1,NPRL2,POLR3D,ACAP3,UNC13A,ANXA5,RAPGEFL1,PTGS1,ARHGAP1,ACTR3B,SAMD4A,PNMA1,SOX6,SPTAN1,DDHD1,FGF9,CEP295,LDHA,IL6R,UBE2K,FOXC1,UBC,ANXA1,RPA1,OXSR1,TRIB3,NSD1,ARID3B,STX1A,HERC1,ACOX1,GPAM,PSAP,BMP4,IGBP1,UQCC1,DOCK6,ANAPC4,KDM4C,CUL7,TRIM16,AAMDC,GPBP1L1,PPARGC1B,MFGE8,CSNK2A1,FAM13A,NLE1,BIRC2,GIT2,HNRNPLL,MAP2K3,ABL2,ECM1,PHF5A,ARHGAP18,DHX33,NCKIPSD,XRCC2,RAN,ETV1,RBCK1,ATF4,GCNT2,MIOS,PPARG,CDK4,ANK2,HSPA5,GMFB,MARCKSL1,SUMO3,LAMA2,BRCA1,KCNH2,ODC1,MLLT10,DYRK1B,HPRT1,ZNF622,TCF7L1,INSIG1,TP53BP1,PER1,E2F4,SOCS4,TNFRSF1A,RAD51B,DPP4,SGSM2,ADAM9,PPP3CC,DLX2,BEND6,UQCC2,C2CD5,CHMP4C,FOXO1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,BARX2,TRIM15,ZIC2,RLF,ARID1B,SPIRE1,RNF40,SUB1,MLX,CEP290,MBD2,NDRG4,GTF2H1,VAPB,CTR9,ICE2,WNT16,LRSAM1,NT5E,CAMKK2,LAMC1,PAXBP1,CRADD,UTP15,OBSCN,MEX3B,SUPT5H,TCF7L2,NR2F1,TBC1D2,ATXN7,SPAG9,IRAK2,PPP1R12B,ARHGAP12,TESC,PRKAR2A,SART1,ID1,CYLD,OLFM2,NTSR1,RIPK1,DENND3,PAG1,PELP1,SEMA6A,PLXNB1,KDM1A,NRF1,JAG1,GRIN2C,DNAJB6,IKBKB,CORO1A,AHCYL1,SPIDR,CASP10,CTC1,PRPF19,SEC24A,KAT8,ARHGAP17,EVL,DDX41,RAB7A,C1QTNF1,VIM,AKAP13,ENC1,USP36,SMAD3,SLC30A3,SIX5,KLF4,ATG7,PUS1,EIF2B3,PKIB,PARD3,UNC13D,MINK1,MAP3K13,AGO2,ZNF346,RBM19,CSNK1A1,FOXP1,ANKRD54,IQGAP2,PTPN2,TMEM161A,FBXO31,CD44,C12orf4,HSD17B12,SMARCAD1,RAP1GDS1,RANGAP1,ARHGEF12,PIK3CB,NEU1,POLR3A,MKX,DKK1,POLR3G,TAF4,TBX3,CSRNP1,MSH3,BCAS3,FNTB,MYRF,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,TNFRSF21,PLRG1,ENAH,PRKCA,RAC3,GABPB2,UBR5,LPIN1,GIPR,EXOC1,S100A10,RNF111,DPH6,MEIS3,SEH1L,TBC1D8,DDN,NR6A1,NOL8,EYA3,TCEB3,CUX1,VSNL1,HSH2D,SEMA3F,SUPT20H,DENND4A,DDX60,SAP30BP,SPOP,SKIL,DDAH2,CCNT1,LSM14A,NSMCE1,ARL6IP5,CFD,SEMA3C,NRP1,BMI1,SPOCK2,RFXAP,SYNPO,ZMAT3,EFNB2,WDR75,IFT57,DROSHA,EGR1,JUP,CDC42EP2,ZHX3,ANKRD17,OPHN1,PID1,CRACR2A,PDCD5,TGFBR2,CHD5,CD226,PRKCE,FKBP1A,ENTPD5,ASAP1,MYC,PLEKHA2,LPCAT1,CAV2,TERF2,ADARB1,EXOSC2,SYNGAP1,RREB1,RAP1GAP2,RAPGEF4,RAP1B,ARID1A,NELFA,PLCB1,ANGPTL4,ARIH2,CAT,KIDINS220,NSF,HIF1A,SPEN,NCOR1,IQSEC2,MAP2K4,SMYD3,AMOTL1,SYT17,BIRC6,FOSL2,PDE3A,BLOC1S2,TERF2IP,CHD7,SLX4,ASNS,SHC1,PPID,LPIN2,DTNBP1,SSBP1,KMT2A,CASP8AP2,BRD4,PREX1,DLG4,SATB2,MED16,SETD7,TBC1D16,STK10,SERP1,ERC1,SNCA,VDR,MSX2,CAMK2D,SMARCC1,DNAJA3,H2AFX,TRAF3,ANXA2,TBXA2R,XRCC4,MID1,FGFBP3,BRAF,TCF3,MON2,IKBKAP,GDPD5,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ABL1,RGS17,ELP5,TRIAP1,RDX,NLGN3,CELF1,EXOSC4,S100A14,DYNC2H1,YBX3,LARP4B,ERRFI1,MAP3K14,PLEKHG4,MBTPS2,SLC40A1,PXN,APEX1,WDFY3,FZD3,KCNMA1,TBRG4,PTK2,KLF6,GUF1,POLR2A,COL26A1,STX18,ATM,SVIL,APAF1,PGAM5,RABEP1,DDIT3,STK4,KAT6A,NF1,ATRX,KMT2E,PTPRA,RCHY1,SIRT2,WNT2B,SMARCB1,ANAPC1,RAP1A,ANAPC11,ANAPC10,RELB,HYAL1,ZEB1,POLR3B,PCOLCE2,SLC35C2,CARM1,TRIM14,PRKACB,SRPK2,ZBTB17,TNK2,DEAF1,TRIM13,GPM6A,FBXW4,SKAP2,SIRT6,VWCE,ARRDC3,CAV1,SGK2,SOX4,KMT2C,SERGEF,ARPC3,TAF9B,RHOU,UBTF,PAF1,GATA6,DNAJC1,RLTPR,MKL2,CTAGE5,CRCP,CLU,ZC3H8,NOCT,MTCH1,VIPR1,RELL2,FN1,TAF1,PAX2,CMTM3,RHBDD1,NAMPT,DDIT4,ELL,SIPA1L3,MCAM,BUD31,SEMA3D,TENM3,NRIP1,XPO5,ELP3,PSMA1,WWC1,LIG4,PRDM1,EIF2A,AGAP1,SYT1,HERPUD1,ISG15,UBE2E1,BICD1,MYBBP1A,FSCN1,RRAGA,PTRH2,ZFP90,PFDN2,TBL1X,FNBP1L,PDE9A,N4BP2L2,TCF12,CHMP2A,DLL4,ASH1L,PCNT,CEMIP,SMARCA4,PBX1,PIBF1,GBF1,MIEF1,RRN3,KCTD11,BRE,CAMTA2,NVL,ITGAX,MET,TSPAN14,C6orf89,HTRA2,MAML3,MOSPD1,PRAME,PHLDB2,GRHL3,ATXN1,TOR1AIP2,DKC1,EDEM2,ZC3H12A,IKZF4,ADNP,COPS5,CEBPZ,ARNTL,DUSP19,HEATR1,DISP1,SCARB1,ARC,TMEM101,TSPAN5,DNAJC2,TNIK,SH2D3A,SUPT6H,CAMK1,DBF4,PDE4B,CLSTN2,ATF7IP,SEMA3E,PPP1R1C,PIP4K2A,BMP6,PRKCH,CTNNBL1,HAS3,SCN1B,TANK,SHMT2,UTS2,AMOT,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,DNMBP,MSX1,FGF2,ZNF821,KDM5A,ASAP3,ARHGAP32,MEN1,PDE2A,SYMPK,HSPA1B,RERE,SERINC1,GADD45A,MPP7,VPS37B,NCBP2,POLR1C,NFKBIB,ZAK,MMP16,ARHGAP27,HRH1 |
| 3.859e-03 | -5.56 | genital_tract | COSMIC cancer mutations | genital_tract | 173 | 35 | 17775 | 2278 |
BRAF,NF1,TNFRSF21,SMARCA4,WDR26,NLE1,DNAH1,RPGRIP1L,SMARCB1,KDM2A,INTS7,SEMA3D,PRICKLE2,KMT2A,YARS,SRPK2,SPTAN1,RPS6KB2,FLNC,LAMA4,NRAS,TTLL5,ADAMTSL3,JMJD1C,TOP3A,SON,PHF6,ATP9B,SMAD3,BAZ2B,EIF4ENIF1,HLCS,SOCS4,ATM,RUNX1 |
| 3.861e-03 | -5.56 | KOBAYASHI_EGFR_SIGNALING_24HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_DN | 242 | 46 | 17758 | 2279 |
SRM,HMGA2,SPRED2,MCM6,MCM10,DBF4,SLC29A1,TUBB6,RMI1,PHLDA2,NOP56,MCM5,TIMELESS,NOC3L,MET,ETV1,PRPS1,TRIP13,NT5E,TMPO,RFC4,RFC3,PSAT1,GINS3,PARP2,UPP1,POLA1,PSMC3IP,KIF15,RANGAP1,PNN,BRCA1,OASL,MCM2,ODC1,NUDT15,RAD54B,CHAF1A,DCBLD2,DKK1,EXO1,POLE2,H2AFX,GALNT10,NOLC1,TMEM158 |
| 3.874e-03 | -5.55 | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_DN | 179 | 36 | 17758 | 2279 |
CCDC53,VTA1,ALG8,NDUFB5,SLC25A12,IKBIP,UBL5,NDUFB3,RPP30,TTC1,ADH5,COPS4,SURF2,PPID,ANAPC10,GTF2H1,CEP63,LYRM5,SNAPC5,ACADS,RFC4,ALG6,PPARG,EIF3J,TMEM126B,TMEM126A,CLNS1A,NME7,COPS5,EIF2S1,UMPS,MED20,BPNT1,ECHDC1,TSPAN5,LMBRD2 |
| 3.874e-03 | -5.55 | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN | MSigDB lists | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN | 179 | 36 | 17758 | 2279 |
PSTPIP2,PDE4B,KLHL18,ARFIP2,RSL1D1,RCAN1,TUBB6,UBL5,POGZ,SOCS1,PMAIP1,NVL,ZCCHC14,EIF3J,TLE3,RAP1B,BCS1L,GNL1,AKAP13,MAT2A,NEU1,FBXO21,TPD52L2,KPNA1,SERF2,TP53BP1,PQBP1,RIOK3,FKBP5,TBL1X,PDCD11,BLMH,KIF1B,AP2S1,MTCH1,LPP |
| 3.877e-03 | -5.55 | lysine-acetylated histone binding | molecular function | GO:0070577 | 17 | 7 | 16491 | 2164 |
SMARCA4,BRD4,KMT2A,BAZ2A,BRD9,TAF1,CARM1 |
| 3.879e-03 | -5.55 | SHEPARD_BMYB_MORPHOLINO_UP | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_UP | 204 | 40 | 17758 | 2279 |
SNX27,HM13,TRIM16,FAM207A,DLGAP4,OLA1,GYG1,FOXO3,PSMF1,PHLDA2,LETM2,MBD2,ZC3H3,HTRA2,TMPO,ALG6,NR6A1,ARRDC3,RDH10,MINA,EXOG,SETD7,NAPEPLD,USP36,ZNF622,TPD52L2,DUS3L,ZNF330,ARL6IP5,DNAJA3,RIOK3,CBWD1,FNTB,ANXA2,SCARB1,POLR1C,PTP4A2,CNDP2,MB21D2,GCSH |
| 3.879e-03 | -5.55 | TCCCRNNRTGC_UNKNOWN | MSigDB lists | TCCCRNNRTGC_UNKNOWN | 204 | 40 | 17758 | 2279 |
CCDC53,ZCCHC8,FAM189B,POLR1A,CSNK2A1,CLINT1,RPP30,TTC1,GART,CEP290,PRMT5,VCL,CNOT4,PRPF19,HMBOX1,MON1A,RB1CC1,POLK,C19orf43,HAUS6,RDH10,COL4A3BP,R3HDM1,DLG4,HDAC8,SON,CCDC150,TMEM186,BSN,PES1,NSD1,LUC7L3,EXOC4,INTS9,BDH2,MBD6,FNBP1L,SMG1,USP15,TMEM33 |
| 3.894e-03 | -5.55 | LIGASE_ACTIVITY | MSigDB lists | LIGASE_ACTIVITY | 95 | 22 | 17758 | 2279 |
SARS,GARS,NARS,PCCA,LIG4,FARS2,VARS,MARS,UBE2K,UBR5,UBE2E1,CAD,FARSA,ASNS,HLCS,ANAPC11,ANAPC10,SLC27A5,XRCC4,YARS,ANAPC4,MTHFD1 |
| 3.898e-03 | -5.55 | RUVBL1 (RuvB-like AAA ATPase 1) | protein interactions | 8607 | 180 | 39 | 16036 | 2270 |
EP400,CUL7,ACTG1,HSD17B10,MLH1,CEP126,TTI1,PELP1,NEDD4,CAD,SRSF2,SHC1,UCHL5,VPS72,CFDP1,MYC,RNF2,FBL,PABPC1,FDFT1,RPS6KB2,FBXW4,TUBA1A,SIRT6,USP49,SMARCAD1,DKC1,UBC,SRCAP,AHNAK,TRRAP,CDK9,COPS5,H2AFX,GPN1,NFRKB,POLR1C,C12orf45,SMG1 |
| 3.905e-03 | -5.55 | HUANG_DASATINIB_RESISTANCE_UP | MSigDB lists | HUANG_DASATINIB_RESISTANCE_UP | 78 | 19 | 17758 | 2279 |
ANTXR2,MYO10,LIMA1,TNFRSF21,UPP1,TFPI,MAP7D1,CAV1,COTL1,TGFBR2,INPP1,DCBLD2,PCDH7,ANXA1,JAG1,CCDC50,PTRF,MET,CAV2 |
| 3.909e-03 | -5.54 | polysome | cellular component | GO:0005844 | 41 | 12 | 17570 | 2233 |
MSI2,NAA38,ATXN2,AGO2,EIF2S1,PSMA1,FUS,YBX3,LARP4B,ABCF1,NAA35,DIS3L2 |
| 3.922e-03 | -5.54 | COPS5 (COP9 signalosome subunit 5) | protein interactions | 10987 | 775 | 136 | 16036 | 2270 |
CUL4A,FEM1C,PLOD1,CSNK2A1,PABPC4,AMBRA1,SMARCB1,SRSF2,RPS16,SREBF2,COPS4,UBAP2L,SRRM2,FTSJ3,SEH1L,CARM1,FBXW4,PPARG,KLHL23,RNMT,SKIV2L2,GNL3,CDK4,HSPA5,SHISA5,MTHFD1L,DDX3X,TP53BP1,FAM114A2,LUC7L3,DNAH2,COPS6,FIP1L1,BLMH,MEF2C,LPP,USP15,TTN,JUP,TRIP6,RHOBTB1,PRPF31,DPF2,HSD17B10,SMAD7,BTBD9,CCDC47,PRPF39,SSR4,IGF2BP3,DDX56,COPS3,IGF2BP1,AGL,PABPC1,WDR61,TRA2A,IMPDH2,EHBP1,ABCF1,POP1,DYNC1H1,PWP1,EPRS,MYBBP1A,KPNA1,SYNCRIP,RPL28,HIF1A,C7orf50,BRSK2,SRP14,USP7,LIN28B,DDX18,BTBD2,SMARCA4,RSL1D1,KLHL18,AP1B1,SAFB2,HNRNPA3,HSPA1A,NOP56,ASNS,BRE,IKBKB,MRPS27,SSBP1,PRPF19,PCMT1,TOR1AIP2,VIM,MEF2D,CCNDBP1,DSP,EIF3H,MAT2A,DHX57,FBXL5,HNRNPR,COPS5,ACP1,FUS,BRCC3,KLHL24,AGO2,SF3A3,MYNN,CSNK1A1,MRPS11,NDUFV1,NOP16,COPS7B,CPNE7,LARP4B,YBX3,FBL,FBXO31,HNRNPM,SPTAN1,TOP1,FAM98A,FBXO17,LSM12,HIST1H4J,UBC,HSPA1B,KLHL22,FBXO21,TPD52L2,HNRNPH3,CUL2,RNF138,EIF2S1,PGAM5 |
| 3.933e-03 | -5.54 | PHLDA3 (pleckstrin homology-like domain, family A, member 3) | protein interactions | 23612 | 24 | 9 | 16036 | 2270 |
TTC27,RARS2,XPO5,TNPO3,SLC25A12,CCDC47,SSR4,IPO4,HNRNPM |
| 3.933e-03 | -5.54 | ZNF212 (zinc finger protein 212) | protein interactions | 7988 | 24 | 9 | 16036 | 2270 |
PTP4A1,ATF4,SUV39H2,PPARGC1B,DPF2,SF3A3,GNL1,ZNF3,SAP30BP |
| 3.933e-03 | -5.54 | PPIH (peptidylprolyl isomerase H (cyclophilin H)) | protein interactions | 10465 | 24 | 9 | 16036 | 2270 |
SNU13,FN1,PRPF31,ITPA,PCMT1,PRPF4,N4BP2L2,UBC,USP15 |
| 3.936e-03 | -5.54 | SMAD binding | molecular function | GO:0046332 | 71 | 18 | 16491 | 2164 |
TCF12,HMGA2,COL5A2,PRDM16,SMAD7,MEN1,TGFBR2,SKI,SMAD3,SKIL,FKBP1A,SNW1,PMEPA1,HIPK2,RNF111,PURB,ZC3H3,USP15 |
| 3.944e-03 | -5.54 | GCGSCMNTTT_UNKNOWN | MSigDB lists | GCGSCMNTTT_UNKNOWN | 67 | 17 | 17758 | 2279 |
PPAT,POLA1,PSPC1,TRA2A,PPP2R2A,POU2F1,UBE2K,GABPB2,SRSF2,SUV39H2,LUC7L3,PDS5B,ATM,USP11,CEP135,YARS,ADK |
| 3.947e-03 | -5.53 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | 173 | 35 | 17758 | 2279 |
PTP4A1,VIPR1,TTN,PCNT,RBM33,ITPRIP,XPC,WDR13,GPR143,FAM8A1,ETFB,IQGAP2,COMMD9,LRP2BP,WDR27,FHIT,SNX29,DIS3L2,TTLL5,IL11RA,PTPRM,RAP1GAP2,ARRDC3,SLC35G1,TEX14,R3HDM2,ENC1,ST3GAL5,TAMM41,ZDHHC11,KLF4,DTD1,IGBP1,SH3PXD2A,LPP |
| 3.956e-03 | -5.53 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | 307 | 56 | 17758 | 2279 |
ZNF254,ZNF292,DNAJC2,AK2,ZNF516,NF1,CLK1,MED13L,RCHY1,NECAP1,RCAN1,TRIM22,BHLHE40,ZNF44,RLF,NLE1,ZNF239,PTPN2,PMAIP1,IFIT5,DNAJB6,ANAPC10,SOCS6,ZEB1,CELF1,NRIP1,MBTPS2,IFRD1,FGF9,SLC3A2,NRAS,RNMT,PPAT,FGF2,MCL1,BRCA1,PITPNB,OASL,KLF6,MAK16,ISG15,ANXA1,GNAI1,BAZ2B,IREB2,GADD45A,ZNF330,TIMM17A,TBPL1,GPN1,PEX13,MAP2K4,MID1,DDIT3,RNF114,TMCC1 |
| 3.973e-03 | -5.53 | APEX1 (APEX nuclease (multifunctional DNA repair enzyme) 1) | protein interactions | 328 | 92 | 23 | 16036 | 2270 |
METTL1,HMGA2,POLB,APEX1,PRDX6,LGALS1,PSMG1,CSNK2A1,HSPA1A,ARIH2,RPA1,TERF2IP,POLR3D,GADD45A,KPNA3,HIF1A,SET,CCDC124,MUTYH,PABPC1,PRPF19,TERF2,SRPK2 |
| 3.977e-03 | -5.53 | HALLMARK_OXIDATIVE_PHOSPHORYLATION | MSigDB lists | HALLMARK_OXIDATIVE_PHOSPHORYLATION | 198 | 39 | 17758 | 2279 |
NDUFA5,SUCLG1,PDK4,NDUFB5,HSD17B10,SLC25A12,OPA1,TIMM10,COX10,NDUFS7,FDX1,ETFB,MRPS11,MRPS30,NDUFB3,SLC25A20,DECR1,NDUFV1,ATP5G2,PMPCA,NDUFA6,FXN,HTRA2,TIMM50,TIMM8B,IDH3G,LDHA,CPT1A,DLST,RHOT2,ECH1,ATP5D,MFN2,ETFDH,RETSAT,TIMM17A,SURF1,BDH2,SLC25A11 |
| 3.992e-03 | -5.52 | FAN1 (FANCD2/FANCI-associated nuclease 1) | protein interactions | 22909 | 16 | 7 | 16036 | 2270 |
RFC4,PMS1,MLH1,RFC3,UBC,FANCD2,FAN1 |
| 3.997e-03 | -5.52 | NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) | protein interactions | 4790 | 152 | 34 | 16036 | 2270 |
HMGA2,COMMD10,BANP,NCOR2,CUL4A,DPF2,RIPK1,RSF1,RPS6KA5,PELP1,COMMD9,IKBKB,RELB,CARM1,DPF3,MPP6,PPARG,ABCC2,BRCA1,MEN1,UBE2K,POLR2A,SPAG9,KPNA3,TP53BP1,COPS5,CDK9,NFRKB,NCOR1,CLU,COPS6,NFKBIB,PDCD11,XRCC4 |
| 4.015e-03 | -5.52 | regulation of histone modification | biological process | GO:0031056 | 123 | 27 | 16441 | 2138 |
WDR61,PAXBP1,SUPT6H,KDM5A,CAMK1,BCOR,BRCA1,SETD7,RPS6KA5,UBR5,KDM1A,SKI,SNCA,SMARCB1,PAF1,RNF40,TADA3,SNW1,NSD1,CAMK2D,CDK9,SET,ATG7,CTR9,NCOR1,KMT2A,MYB |
| 4.016e-03 | -5.52 | peptide metabolic process | biological process | GO:0006518 | 508 | 87 | 16441 | 2138 |
GGT1,IMMP2L,EIF3C,RARS2,AARS2,MRPL10,RPS29,AARS,PABPC4,DENR,MRPS30,SRPRB,FARSA,MMP7,RPS16,MRPS27,GSTA4,ETF1,YARS,NARS2,GDAP1,GARS,EIF4E3,NARS,HARS,EIF3J,MTIF2,MRRF,NLN,EIF3H,MGST1,WARS,DDX3X,EEFSEC,G6PD,COPS5,BDH2,FTSJ1,PAM,XPNPEP1,EIF2B3,CARS,SARS,LARS2,AGO2,FARS2,PCSK7,VARS,SSR4,GFM2,YARS2,IGF2BP3,MRPS11,EIF2S2,GATC,UNC13A,HARS2,SELT,MRPL21,PPA1,PABPC1,RPL22L1,PCSK6,RPS6KB2,GTF2H3,WARS2,EIF4A2,MRPS10,MARS,EIF2A,CORIN,EIF5B,GUF1,ABCF1,TARS,MRPL36,EPRS,RARS,RPL28,GSTO2,SRP68,EIF2S1,CDKAL1,DPEP1,GGT7,CNDP2,SRP14 |
| 4.025e-03 | -5.52 | MDM2 (MDM2 proto-oncogene, E3 ubiquitin protein ligase) | protein interactions | 4193 | 731 | 129 | 16036 | 2270 |
CUL4A,EIF3C,PRDX6,ACTG1,PRKCSH,RCHY1,HMOX2,SRPRB,ABL2,RAP1A,CMSS1,RASSF3,PAK1IP1,SUCLG2,RAN,SRRM2,TMPO,SNU13,TRIM13,SLC3A2,SESN2,NRAS,ATF4,SIRT6,GNL3,HSPA5,EHMT1,SOX4,MCM2,STOML2,PYCR1,UBTF,PAF1,DDX3X,TRRAP,AHNAK,CLU,TPM1,BANP,AK2,EGR1,JUP,FOXO1,ANKRD17,TAF1,HSD17B10,PHGDH,PDCD5,ETFB,IGF2BP3,RNF40,UBE3A,VAPB,ALDH18A1,PABPC1,FDFT1,NIPSNAP1,MTHFD1,RYR2,USP10,ARIH2,MTHFD2,SYNCRIP,HIF1A,TRAP1,CDK9,PTRH2,SENP3,SRP14,USP7,NDUFA5,SART1,SMARCA4,PBX1,MYH9,HNRNPA3,HSPA1A,FLNB,DECR1,FARSA,RNF2,FHIT,SSBP1,SERPINH1,GLTSCR2,RAB7A,NPM3,DLG4,DSP,FKBP3,S100A16,MAT2A,RAD54B,RANBP2,RBBP8,HNRNPR,HIPK2,COPS5,G6PD,RPS6KB1,ANXA2,FUS,XPC,SF3A3,CSNK1A1,FOXO3,NEDD4,ABL1,SURF2,SHMT2,CELF1,RPL22L1,HNRNPM,SPTAN1,TOP1,APEX1,PSPC1,USP42,TPM4,PTK2,UBE2K,ECH1,UBC,TPD52L2,RARS,GADD45A,SET,ATM,IPO4 |
| 4.054e-03 | -5.51 | human chr22q13 | chromosome location | human chr22q13 | 22 | 7 | 26250 | 2590 |
RANGAP1,SNU13,SREBF2,TTC38,FAM118A,TRMU,MIEF1 |
| 4.074e-03 | -5.50 | GSE7852_LN_VS_FAT_TREG_UP | MSigDB lists | GSE7852_LN_VS_FAT_TREG_UP | 192 | 38 | 17758 | 2279 |
CDCP1,PIGN,TTC27,ADAMTS6,NUP160,BZW2,PIP4K2A,MRPS11,MLX,NUP133,RABGAP1L,BCAP29,SEH1L,RABEPK,C18orf21,RBCK1,APEX1,SLC38A1,HAUS6,HIST1H2BL,TTC28,DHX57,EXOC6,BTBD11,CAMK2D,TOE1,ZNF266,BAZ2B,TRMT5,STX1A,LUC7L3,WDR73,CRCP,ZNF18,CNDP2,BMI1,FAM118A,SYNPO |
| 4.074e-03 | -5.50 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | 192 | 38 | 17758 | 2279 |
ARHGAP26,MCM6,SHQ1,PCNT,LAGE3,PIK3R4,WDR37,PLA2G12A,HLTF,CUTC,MTUS1,RNFT2,ZNF586,VPS72,MCM5,TRIAP1,NCKIPSD,TTC3,OGG1,HN1,TMPO,RFC4,LAMC1,WDFY3,PARP2,KCNMA1,ATP6V0A1,TBC1D16,USP46,RPA1,FBXO21,FGFBP1,MKL2,POLR3E,TSSC1,HMBS,RWDD2B,ZMAT3 |
| 4.074e-03 | -5.50 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP | 192 | 38 | 17758 | 2279 |
SPRED2,RWDD1,DBF4,KIF5C,NLE1,MFHAS1,YARS2,CAD,CHN1,ANAPC1,MPHOSPH10,PMAIP1,NOP16,ZNF85,AVEN,TOMM34,LONP1,PTPRK,MTHFD1,FAM98A,GINS3,TSTA3,STAMBP,EIF3J,KIF15,R3HDM1,PSMG1,MARCKSL1,TBRG4,ODC1,EVI5,PAF1,SLC39A14,POLE2,PTRH2,DPP4,POLR1C,BLMH |
| 4.074e-03 | -5.50 | GSE17721_CTRL_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_6H_BMDM_UP | 192 | 38 | 17758 | 2279 |
SLC37A3,SARS,ASCC1,ESCO1,PTPRA,CERS5,ZNF280C,ATG2B,SSR4,FRRS1,SLC39A11,SLC25A20,FAM50A,GATC,ARMC6,APLF,RASSF3,NCKIPSD,METTL8,CORO1A,TSPAN14,MCEE,SLC40A1,BAZ2A,ATG12,TTYH2,TPRA1,CPT1A,EIF3H,CLNS1A,PGD,MGAT2,KLHL22,HELZ,SRRD,ACOX1,FDPS,ADK |
| 4.074e-03 | -5.50 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP | 192 | 38 | 17758 | 2279 |
SRM,BRAF,PLRG1,C16orf45,FOSL2,SLC6A8,FAM13A,RPS6KA5,FLNB,MAN1A1,SMARCB1,USPL1,FMNL1,PDE10A,ATIC,BANF1,PMPCA,SERPINH1,AHCYL1,PRMT3,TOMM34,SLC25A1,DLG4,BMS1,AKAP13,IMPDH2,MCM2,MEN1,ODC1,CPT1A,EHBP1,ZBTB25,UBTF,SRRD,CCDC85B,SRP14,CORO2B,HS2ST1 |
| 4.074e-03 | -5.50 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | 192 | 38 | 17758 | 2279 |
ABCA3,ID1,EIF3C,UTP14A,SF3A3,PHGDH,HSPA1A,ATXN7L1,ECM1,PTRF,NCKIPSD,RAN,MEIS3,ALDH18A1,AHCYL1,SAMD4A,SLC25A1,PTPRK,TMC7,GARS,SLC38A1,TLE3,DHX34,RSBN1,DSP,PLCXD2,HSPA1B,EXO1,TRIB3,STX1A,ADAT2,LUC7L3,DNAH17,CASS4,ZRANB2,NRP1,PTPN14,LRCH1 |
| 4.081e-03 | -5.50 | regulation of heart rate by cardiac conduction | biological process | GO:0086091 | 26 | 9 | 16441 | 2138 |
CAMK2D,DSC2,JUP,SCN1B,ANK2,DSG2,CAV1,KCNH2,DSP |
| 4.081e-03 | -5.50 | regulation of synaptic vesicle transport | biological process | GO:1902803 | 26 | 9 | 16441 | 2138 |
BRAF,RAP1A,STX1A,RAP1B,BTBD9,SEPT5,SYNJ1,NAPA,SNCA |
| 4.095e-03 | -5.50 | POLR3H (polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)) | protein interactions | 171568 | 20 | 8 | 16036 | 2270 |
POLR3D,HSPA5,POLR3E,CRCP,POLR3B,POLR1C,POLR3A,POLR3G |
| 4.095e-03 | -5.50 | MAP1LC3C (microtubule associated protein 1 light chain 3 gamma) | protein interactions | 440738 | 20 | 8 | 16036 | 2270 |
TFCP2,WDFY3,RB1CC1,ATG3,ATG7,PIK3R4,USP11,SF3A1 |
| 4.095e-03 | -5.50 | TRMT61A (tRNA methyltransferase 61A) | protein interactions | 115708 | 20 | 8 | 16036 | 2270 |
METTL1,KPNA1,SKIV2L2,RBFOX2,COPS5,ARHGEF12,MARS,AP1B1 |
| 4.095e-03 | -5.50 | VAMP4 (vesicle associated membrane protein 4) | protein interactions | 8674 | 20 | 8 | 16036 | 2270 |
STX8,STX18,AP1M1,VTI1A,CSNK2A1,VPS52,PACS1,VPS53 |
| 4.095e-03 | -5.50 | CNOT6 (CCR4-NOT transcription complex subunit 6) | protein interactions | 57472 | 20 | 8 | 16036 | 2270 |
MMP7,AGO2,CNOT6,TNKS1BP1,PABPC1,ZMAT3,CHAF1A,TNRC6A |
| 4.104e-03 | -5.50 | EIF5B (eukaryotic translation initiation factor 5B) | protein interactions | 9669 | 42 | 13 | 16036 | 2270 |
EIF3C,FN1,TFCP2,GLTSCR2,SIRT7,ABCF2,CSNK2A1,GNL1,BRCA1,DKC1,YBX3,UBR4,FTSJ3 |
| 4.104e-03 | -5.50 | WDR33 (WD repeat domain 33) | protein interactions | 55339 | 42 | 13 | 16036 | 2270 |
ZNF622,UTP14A,TRA2A,SMARCAD1,CDK4,FIP1L1,CPSF3,BMI1,SYMPK,CDK6,ISG15,RPA1,CLK2 |
| 4.104e-03 | -5.50 | WDR4 (WD repeat domain 4) | protein interactions | 10785 | 42 | 13 | 16036 | 2270 |
DCTPP1,METTL1,P3H1,SURF2,ALAD,BIRC6,XPO5,PPP2R2A,ADSL,FAM118A,SRP14,ERC1,TERF2 |
| 4.104e-03 | -5.50 | RPF2 (ribosome production factor 2 homolog) | protein interactions | 84154 | 42 | 13 | 16036 | 2270 |
PES1,DDX56,NIFK,CUL7,DDX24,UTP14A,DDX18,SIRT7,RNF2,DKC1,FTSJ3,ZC3H3,PUM3 |
| 4.114e-03 | -5.49 | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | MSigDB lists | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | 275 | 51 | 17758 | 2279 |
KCTD7,ID1,PDK4,SIRT2,GIPR,PRKCH,ATXN7L1,NUBPL,ASNS,MLX,MYC,MAD1L1,EXOSC4,ZNF460,LPCAT1,PLEKHA4,SAMD4A,ZC3H3,NUDC,GARS,AP4S1,TSTA3,AOC2,PSMC3IP,WDHD1,C5AR1,ATP6V0A1,MAPK1IP1L,PTK2,SPOP,OSBPL1A,PAF1,TAF2,TPD52L2,TRRAP,SPAG9,NSF,SIX5,HIF1A,LUC7L3,TAF4,RIOK3,CRCP,FIS1,KIAA0196,BMP4,NFKBIB,NAPA,BRD9,AP2S1,LAMA5 |
| 4.120e-03 | -5.49 | anaphase-promoting complex | cellular component | GO:0005680 | 22 | 8 | 17570 | 2233 |
ANAPC1,CUL7,CDC16,ANAPC13,ANAPC11,ANAPC10,ANAPC4,MAD2L2 |
| 4.122e-03 | -5.49 | KIM_WT1_TARGETS_DN | MSigDB lists | KIM_WT1_TARGETS_DN | 427 | 74 | 17758 | 2279 |
ZNF292,CYP24A1,NDUFA5,PHF3,CUL4A,ID1,WDR13,LAGE3,TBCCD1,POP5,STAM,FARSA,ASNS,PMAIP1,DNAJB6,SLC38A2,TMEM120B,PERP,TMPO,SLC38A6,PMS1,PARP2,CPOX,HSPA5,EFHC1,SERP1,GNAI1,GLS,COPS5,ARL4A,SEMA3C,NRP1,YEATS2,PRPF31,ZCCHC8,RHOBTB1,SEC24D,DPF2,DBF4,ID2,PLA2G12A,LIAS,TGFB2,DDIT4,IGF2BP3,PI4KB,CTR9,SHMT2,RANBP6,BDNF,PRIM2,ELOVL6,TBRG4,MARS,RANGAP1,RSBN1,TPRA1,AGAP1,MBNL2,ACOXL,TCF7L2,RDH11,IRS1,MGAT2,ASCC3,VPS13C,BAZ2B,ORC5,CCDC85B,TBPL1,APAF1,BMP4,NR2F2,IQSEC2 |
| 4.122e-03 | -5.49 | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | 427 | 74 | 17758 | 2279 |
USP7,PIGM,ABCA3,PTPRA,OSBPL9,SLC2A1,TMEM109,PLOD1,SLC29A1,FLNB,ECM1,SREBF2,S100A10,ZKSCAN1,SLC39A7,SLC38A2,CLCN6,MMP14,ANKRD11,VCL,C6orf89,ARHGAP17,SFSWAP,WLS,HSPA5,ATOX1,CUX1,SEMA3F,EDEM2,SON,TMEM186,FGFR1,SLC39A14,DNTTIP1,ZNF266,SLC4A7,RIOK1,NRP1,METTL2B,TMEM33,SHQ1,FN1,ITPRIP,DPF2,MAPK8IP3,LETMD1,WDR26,RTN4,SFI1,MFSD10,ABCA7,ANXA7,PI4KB,PPIL2,NISCH,KDELC1,PTGS1,HSD17B12,HMGCR,KDM6B,LAMC1,SIGMAR1,TRA2A,TYW1,ATAT1,KLF6,NEU1,SLC23A2,SERINC1,ZZEF1,GLG1,SLC16A1,PSAP,DDIT3 |
| 4.126e-03 | -5.49 | BOYLAN_MULTIPLE_MYELOMA_D_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_UP | 84 | 20 | 17758 | 2279 |
YDJC,GPHN,CLYBL,POLR1A,C14orf159,OBSCN,SLC35F2,SPATS2,SPIRE1,NRF1,GART,PDZD2,L3MBTL3,ARL4A,MYC,AGTPBP1,FUT11,DDIT3,ZNF507,USP15 |
| 4.126e-03 | -5.49 | RUAN_RESPONSE_TO_TNF_DN | MSigDB lists | RUAN_RESPONSE_TO_TNF_DN | 84 | 20 | 17758 | 2279 |
LAMA4,ACADS,AOC3,AK2,PPARG,IDH3G,REEP5,ECH1,ALAD,ENTPD5,ACOX1,ARL4A,PEMT,HIPK2,CFD,HK2,ME1,SCARB1,GPAM,NRIP1 |
| 4.149e-03 | -5.48 | PID_FANCONI_PATHWAY | MSigDB lists | PID_FANCONI_PATHWAY | 46 | 13 | 17758 | 2279 |
RFC4,RFC3,BRCA2,PALB2,FANCD2,H2AFX,TOP3A,FAN1,ATM,ATRIP,BRCA1,RMI1,RPA1 |
| 4.149e-03 | -5.48 | SESTO_RESPONSE_TO_UV_C5 | MSigDB lists | SESTO_RESPONSE_TO_UV_C5 | 46 | 13 | 17758 | 2279 |
HMGA2,NCOR2,RBBP8,JAG1,PAFAH1B1,SLK,MYC,PIK3R4,ZNF148,MCL1,ITGB4,TGFBR2,CLINT1 |
| 4.155e-03 | -5.48 | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 125 | 27 | 17775 | 2278 |
KDM3B,ASH1L,BRAF,KMT2D,FN1,PRDM16,EXOC6B,LPCAT2,KCNMA1,ZBED4,ARHGEF10,GTF2IRD1,ID2,TOR1AIP2,ARID1A,ST3GAL6,SEMA6A,FLNB,ZNF425,DST,CDC16,MYC,CSMD3,TIMELESS,APAF1,ZCCHC7,TRIM36 |
| 4.166e-03 | -5.48 | WONG_ADULT_TISSUE_STEM_MODULE | MSigDB lists | WONG_ADULT_TISSUE_STEM_MODULE | 694 | 113 | 17758 | 2279 |
ASH1L,ID1,CELSR3,MFGE8,PBX1,ENAH,TUBB6,SSBP2,SLC9B2,HSPA1A,PPP1R9A,LPAR3,FLNB,LPIN1,SKI,DST,ESAM,AMPD3,ZKSCAN1,MYH3,RELB,NBEA,GSTA4,TTC3,SERPINH1,PRKACB,PTPRK,PHLDB2,ANTXR2,EVL,SLC3A2,LGALS1,ARHGEF10,MARCKSL1,LRRC8A,CAV1,LAMA2,SOX4,TTC28,STK10,MGST1,OSBPL1A,RHOU,VDR,HLA-DMA,IQCH,TP53BP1,PER1,KLF4,HOXA3,HSPB8,LARGE,TPM1,SYNPO,CEP170,RBP1,LPP,EFNB2,AOC3,FN1,CLK1,CMTM8,SMAD7,ID2,BARX2,SEMA3E,C11orf54,BHLHE40,FOXP1,PHLDA2,SLC1A1,MAN1A1,DDIT4,PRKCE,ABL1,NAV1,SCN1B,LRP2BP,PCK2,ERRFI1,NRIP1,ACTR3B,SOX6,NIPSNAP1,ADARB1,MSI2,SIK3,BDNF,LAMC1,CRIM1,ELOVL6,KCNMA1,HOMER2,PTPN12,FERMT2,RYR2,ARHGAP32,PDE2A,KLF6,FOXC1,ISG15,NR2F1,HSPA1B,TRIB3,PXDN,PMEPA1,ACOX1,FNTB,ZFP90,DTD1,SORCS2,RABEP1,DDIT3 |
| 4.168e-03 | -5.48 | GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN | 186 | 37 | 17758 | 2279 |
HES6,CSNK2A1,WDR37,HLTF,C1orf52,DENND3,GIT2,KDM1A,ANKRD54,TRIAP1,VGF,LPIN2,DYNC2H1,LYST,VPS13B,DDHD1,FMNL3,DEAF1,ANTXR2,FBXW4,DNMBP,SFSWAP,C19orf43,ZBED4,XPO5,ZMYM5,ZDHHC14,TPRA1,MAK16,PHF6,RHOU,MSRA,TRRAP,ZZEF1,CEBPZ,ZNF598,ZNF507 |
| 4.168e-03 | -5.48 | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_DN | 186 | 37 | 17758 | 2279 |
BANP,AK2,LYRM4,LIN28B,CCDC58,UTP14A,SIRT7,FARS2,NUP43,STK33,NOS1AP,DCTPP1,NUBPL,PSMG4,SETD5,BANF1,MRPL21,ZNRD1,CAV2,MPST,GTF2H3,TIMM8B,KCNQ3,NPM3,DHX34,PSMG1,FERMT2,SLC35F2,C11orf49,LAMA2,TRAPPC6B,MGST1,ARMC3,STOML2,ALKBH3,CCDC146,NFKBIB |
| 4.168e-03 | -5.48 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDM_DN | 186 | 37 | 17758 | 2279 |
CUL4A,SIRT7,DBF4,PIGH,ZNF346,CLINT1,PIBF1,FOXO3,RHBDD1,ANAPC1,MCAM,GATC,PHKA1,NT5C,CLDND1,POLR1B,RREB1,POLK,ANKMY2,GMFB,MEF2D,ATP8B2,SERP1,POLR3A,MFN2,MGAT2,SRCAP,ARHGAP21,ARNTL,ORC5,SURF1,MSH3,CRCP,ADAM9,FNTB,BRCC3,MEF2C |
| 4.168e-03 | -5.48 | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | MSigDB lists | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | 186 | 37 | 17758 | 2279 |
NDUFA5,SDSL,MMRN2,PRKAB2,SLC25A12,PTPN2,MMP7,ASNS,LYPLAL1,ZNHIT6,HIBCH,LDLRAD3,COQ3,AKAP11,RABEPK,ACSL5,METTL1,UPP1,TMEM126A,NOL8,TMEM216,PHACTR2,EIF2A,APTX,SGK2,CLNS1A,ATP9B,CCDC28B,HPRT1,WDR73,WDR7,ATM,RIOK1,FKBP5,UMPS,EIF2B3,N4BP2L2 |
| 4.191e-03 | -5.47 | intrinsic apoptotic signaling pathway in response to DNA damage | biological process | GO:0008630 | 72 | 18 | 16441 | 2138 |
POLB,TMEM109,CDIP1,MCL1,SHISA5,MLH1,BRCA1,DDIT4,ABL1,SNW1,BRCA2,PMAIP1,HIPK2,TNFRSF1A,ATM,AEN,FNIP2,HTRA2 |
| 4.191e-03 | -5.47 | fatty acid catabolic process | biological process | GO:0009062 | 72 | 18 | 16441 | 2138 |
MCEE,ACADS,SESN2,PCCA,CPT1A,ACOXL,MMAA,LPIN1,ECH1,ETFB,PEX7,ETFDH,DECR1,ACOX1,LPIN2,BDH2,PEX13,CPT1C |
| 4.207e-03 | -5.47 | pheochromocytoma | COSMIC cancer mutations | pheochromocytoma | 328 | 59 | 17775 | 2278 |
DCTN3,HERC2,PRPF38B,BRAF,RBM33,BIRC6,ZCCHC8,NF1,ATRX,LPCAT2,ZNF280C,CACNA1H,SMARCA4,ZNF107,WDR26,SPATS2,MLH1,PIBF1,GIGYF2,FAM8A1,CMTM3,ABCA7,SMARCB1,CAD,ABL1,PDZD2,DHX37,YLPM1,ZEB1,CTR9,MET,CAV2,PTPRK,TSHZ1,SCAF11,COL17A1,NRAS,ALG6,ZNF195,KMT2C,MEN1,ANKRD20A4,ZNF407,FGFR1,EXOC6,DYNC1H1,ASCC3,AHNAK,PALB2,VCAN,DNAH17,MSH3,ATM,IFT140,RWDD2B,HEATR1,WDR33,ZNF598,SMG1 |
| 4.228e-03 | -5.47 | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | MSigDB lists | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | 36 | 11 | 17758 | 2279 |
SMAD3,SKIL,NCOR2,CCNT1,CDK9,E2F4,MYC,SMAD7,NCOR1,MEN1,SKI |
| 4.238e-03 | -5.46 | KEGG_LYSINE_DEGRADATION | MSigDB lists | KEGG_LYSINE_DEGRADATION | 41 | 12 | 17758 | 2279 |
NSD1,ASH1L,SETD1B,SUV39H2,EHMT2,SETD2,EHMT1,PLOD1,SETD7,DLST,TMLHE,DOT1L |
| 4.243e-03 | -5.46 | CYTOPLASMIC_PART | MSigDB lists | CYTOPLASMIC_PART | 1354 | 206 | 17758 | 2279 |
LETM1,EIF3C,MRPL10,TUBE1,IKBIP,TOM1L1,RTN1,DST,PDZD2,PMAIP1,ATP5G2,ATG3,TRMU,ME1,SLC27A5,NDUFA6,FXN,LONP1,TIMM50,ACADS,ABCC4,AP4B1,ATOX1,KIF15,MSRB3,MCL1,CAV1,KRTCAP2,FOXRED1,PEX1,TIMM44,CCDC3,BRCA2,DNAJC1,MPV17,BDH2,FIS1,NRP1,TPM1,MTCH1,TNNC1,DCTN3,TTN,FN1,STX8,HSD17B10,PCSK7,DPM3,CLINT1,TIMM10,ETFB,NDUFS7,DOPEY1,EIF2S2,PI4KB,CEP290,ATXN2,PIGG,VAPB,LPCAT1,MAP3K12,TOMM34,CAV2,HMGCR,HSD17B14,MTHFD1,RABEPK,NIPSNAP1,VOPP1,USE1,TIMM8B,IFNGR2,EIF4A2,BCS1L,EIF2A,CPT1A,HERPUD1,MTHFD2,SRP68,D2HGDH,SURF1,TMEM117,PEX13,PDLIM5,DHCR7,SRP14,COG5,DMXL2,SART1,ABCA3,SUCLG1,PAFAH1B1,NTSR1,PDK4,MYO7A,PIGH,MYH9,GBF1,EEA1,HSPA1A,RPGRIP1L,FDX1,DECR1,SPG21,IDI1,DNAJB6,SNTG2,NBEA,CORO1A,CEP63,SERPINH1,VCL,HTRA2,LYST,MALL,FAM172A,PDK1,MTIF2,EIF3J,RAB7A,CPOX,PCMT1,PREX1,DLG4,CA5B,POLG2,ERC1,SERP1,TMEM186,EIF3H,ATP5D,PLIN2,TAMM41,SLC30A3,CDC16,YIPF2,COPS5,DNAJA3,TIMM17A,LARGE,PAM,SLC25A11,SEPT5,EIF2B3,XRCC4,AP2S1,RAB30,MAPT,DMGDH,BCKDK,MAP3K13,VPS45,TRAK1,SLC25A12,MAP1S,ARFIP2,RTN4,AKT1S1,NOL3,OPA1,MRPS11,MAN1A1,PEX7,NDUFV1,PTRF,TRIAP1,DCTN4,PMPCA,SHMT2,DYNC2H1,PCK2,AMOT,NT5M,SLC25A1,SPTAN1,PPP1R9B,APEX1,ZFYVE1,TMEM126A,ABCF2,TPM4,LDHA,TBRG4,MRPS10,YIPF3,MEN1,RHOT2,TMEM187,ECH1,MFN2,HSPA1B,YIF1A,RETSAT,GPC2,SERINC1,HERC1,STX18,SET,GLG1,EIF2S1,SVIL,APAF1,NDUFS5,RABEP1,KIF1B,GCSH |
| 4.265e-03 | -5.46 | JI_RESPONSE_TO_FSH_UP | MSigDB lists | JI_RESPONSE_TO_FSH_UP | 73 | 18 | 17758 | 2279 |
LAMA4,KAT8,FADS1,ACADS,XPC,ISG15,ECH1,SPOP,PAF1,IDI1,FDPS,SQLE,ZNF148,CLU,RBP1,FDFT1,HMGCR,TBC1D8 |
| 4.272e-03 | -5.46 | regulation of mRNA metabolic process | biological process | GO:1903311 | 106 | 24 | 16441 | 2138 |
PTCD2,SUPT6H,RBFOX2,SFSWAP,AGO2,DHX34,JMJD6,SUPT5H,CDC73,HSPA1A,MBNL1,RNF40,PAF1,SNW1,SRSF2,NSRP1,CCNT1,CDK9,CTR9,NCBP2,AHCYL1,PABPC1,PRPF19,SRPK2 |
| 4.282e-03 | -5.45 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | 341 | 61 | 17758 | 2279 |
CHST11,MCM6,MCM10,EGR1,C10orf2,URB2,SLC2A1,RPS6KA5,HSPA1A,GABPB2,PAIP2,DCTPP1,GART,IDI1,SLC38A5,NOP16,PYCRL,MCM5,MYC,XRCC2,SLC38A2,EXOSC4,GEMIN4,LPCAT1,PRPS1,TRIP13,SEH1L,IPO11,DBN1,RFC3,MPP6,PDK1,GINS3,PSAT1,RNMT,RB1CC1,POLA1,PSMC3IP,TCEB3,UTP15,NOL6,BRCA1,DCUN1D5,MCM2,DKC1,HERPUD1,HSPA1B,CHAF1A,EXO1,SLC39A14,ARHGAP21,TSR1,TOE1,INSIG1,POLE2,H2AFX,SQLE,SLC16A1,SLC25A19,UMPS,DHCR7 |
| 4.293e-03 | -5.45 | DDAH2 (dimethylarginine dimethylaminohydrolase 2) | protein interactions | 23564 | 33 | 11 | 16036 | 2270 |
FN1,ANXA7,CDK4,RAP1B,RPS6KA5,ZAK,CDC73,PPA1,TRIP13,VAC14,CLNS1A |
| 4.299e-03 | -5.45 | positive regulation of viral transcription | biological process | GO:0050434 | 56 | 15 | 16441 | 2138 |
ELL,SNW1,GTF2H3,SUPT4H1,CCNT1,CDK9,TCEB3,GTF2H1,SMARCA4,NCBP2,RSF1,NELFA,SUPT5H,POLR2A,SMARCB1 |
| 4.328e-03 | -5.44 | skin-trunk-malignant_melanoma | COSMIC cancer mutations | skin-trunk-malignant_melanoma | 2752 | 396 | 17775 | 2278 |
GGT1,CDCP1,PLRG1,NAT10,SYNJ1,UBR5,PABPC4,PCDH7,PDZD2,SREBF2,FXN,SPAG6,CSGALNACT2,ZNF646,SLC38A6,NRAS,RNMT,PTPRM,EHMT1,EYA3,VSNL1,CUX1,RFX2,WDHD1,AKAP12,SEMA3F,SON,DDX60,SLC50A1,OSBPL1A,AHNAK,BRCA2,TRRAP,SH3RF1,ZNF81,VPS13D,DNAH2,RIOK1,NRP1,SPOCK3,ZNF532,ZMAT3,PTPN14,HERC2,EP400,TMEM63C,ANKRD17,ZHX3,FAM189B,TRIO,DLGAP4,PIK3R4,RSF1,CDC73,MTUS1,TECTA,RBM20,C6orf48,UBE3A,PI4KB,DHX37,USPL1,SCAF1,ASAP1,CACNB2,MYC,MED24,IGF2BP1,GTF3C3,MAP3K12,FMNL2,NOM1,RABEPK,COL17A1,RREB1,PRDM16,RAPGEF4,TYW1,RDH10,ZNF512B,RYR2,ARID1A,ARRDC4,PLCB1,MTR,ABCF1,ARIH2,DYNC1H1,ASCC3,VPS13C,LRP1B,NME7,CLASRP,FGFBP1,LEMD3,VCAN,SPEN,ZCCHC6,CNDP2,IQSEC2,SRP14,COG5,RTTN,DNM3,ZNF516,RWDD1,NECAP1,GRINA,PTPRG,FLNB,TRIM66,CHD7,CD96,ZNF827,SLX4,FMNL1,CLCN6,NBEA,TTC3,CEP63,MSH4,PEG10,KMT2A,RFC4,GARS,KMT2D,NPM3,MTIF2,ARHGEF10,ADAM32,PCNXL2,PNN,GALK2,GSTCD,DSP,PDE8B,BAZ1A,ARHGAP21,CDC16,ELP2,KDM4B,ASTN2,HIPK2,WDR7,HOXA3,IFT140,BRCC3,LAMA5,CEP170,YEATS2,MID1,TRIM36,LRCH1,MORC2,ZNF786,SSH2,BRAF,NFX1,RTN4,GDPD5,GIGYF2,POM121,NEDD4,ZNF483,NEBL,ACAP3,UPF2,ERRFI1,SPTAN1,CLK2,FER1L5,TTPAL,FGF9,VPS37A,WDFY3,ZC4H2,GUF1,TRIB3,SRCAP,NME1-NME2,HELZ,HERC1,ACOX1,SRD5A3,RNF138,SVIL,MYOM2,STK4,CYP24A1,CUL7,ATRX,NF1,GPBP1L1,MFGE8,FANCD2,TRPM6,CSNK2A1,SLC29A1,BCOR,STK33,GIT2,BIRC2,RTN1,ZNF804A,ABL2,DST,PHKA1,YLPM1,MARVELD2,ANKRD11,RELB,ZEB1,GPATCH1,POLR3B,HCFC2,SRPK2,VPS13B,DSC3,CHD9,ATF4,SKAP2,MIOS,ABCC4,ANK2,TSN,KSR2,PSMG1,LAMA2,KMT2C,KCNH2,ST3GAL5,PEX1,KIF16B,CHAF1A,GEMIN5,TMEM132B,EPN2,LSS,TP53BP1,DNAJC1,FAM114A2,CTAGE5,CSMD3,PPP3CC,GALNT10,MAGI1,BEND6,CHMP4C,AK2,CLK1,TAF1,TRIM15,EVPL,QSER1,XPO7,RLF,ARID1B,DOPEY1,KIAA1958,SIPA1L3,ZNF358,CEP290,WDR27,ATXN2,TIMELESS,PNPLA3,ALDH18A1,ZCCHC7,AKAP11,N4BP2,MTHFD1,RANBP6,XPO5,SETD2,JMJD1C,TBXAS1,WDR25,OBSCN,ZNFX1,PRDM1,SUPT5H,CORIN,ANKRD20A4,ACOXL,DNAH14,TCF7L2,TBC1D2,BICD1,SPAG9,FAM135A,FAT1,INTS5,DNAH17,SDCCAG8,EXOC4,HK2,CASS4,PPP1R12B,KIAA1328,ZFP90,TBL1X,GGT7,C7orf26,TCF12,USP7,ASH1L,PCNT,ARID2,CELSR3,NTSR1,TMEM183A,GPR143,SMARCA4,COBLL1,ARSJ,TNKS1BP1,UBTD2,DDX60L,PLXNB1,ZSCAN5A,CAD,VPS18,METTL16,DUS4L,RPS6KL1,FGGY,SNTG2,SLC38A2,ANKRD24,ZNF142,MYH15,MET,ITGAX,IPO11,CTC1,TMEM200A,PHLDB2,COL5A2,PTBP2,NARS,MANBAL,CPOX,ATXN1,R3HDM1,SLC35F2,ATP8B2,UBR4,USP36,BTBD11,SMAD3,ARMC4,RANBP2,ADNP,COPS5,ATG7,ZNF436,NFASC,NFRKB,HEATR1,SMG1,PARD3,SUPT6H,DYM,DBF4,CLSTN2,SEMA3E,FOXP1,RMI1,POGZ,MAN1A1,IL17RE,SACS,SCN1B,TMEM161A,DSG2,DDX31,POLR1B,AMOT,TOP1,KDM6B,ADAMTSL3,LRRIQ1,KDM5A,ABCF2,EXOG,NAALADL2,MKX,ZNF221,CTIF,DSC2,L3MBTL3,CUL2,BCAS3,MSH3,RBM26,GCSH |
| 4.329e-03 | -5.44 | HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1) | protein interactions | 3181 | 164 | 36 | 16036 | 2270 |
CUL7,CUL4A,FN1,HSD17B10,NFX1,MAP1S,CSNK2A1,MBNL1,HNRNPA3,DENR,IGF2BP3,SRSF2,BRE,SERPINH1,SRRM2,ZMYM2,TOP1,RPS6KB2,ITPA,ABCF2,LIG4,BRCA1,FKBP3,ABCF1,S100A16,PHF6,ISG15,UBC,RPA1,HNRNPH3,COPS5,CDK9,CUL2,H2AFX,COPS6,ZMAT3 |
| 4.336e-03 | -5.44 | TNP1 (transition protein 1 (during histone to protamine replacement)) | protein interactions | 7141 | 9 | 5 | 16036 | 2270 |
CSNK2A1,PRKCA,PPARG,PRKACB,SDCBP2 |
| 4.336e-03 | -5.44 | KLHL8 (kelch-like family member 8) | protein interactions | 57563 | 9 | 5 | 16036 | 2270 |
ATXN1,USP7,COPS6,BMI1,COPS5 |
| 4.350e-03 | -5.44 | ARPC1B (actin related protein 2/3 complex subunit 1B) | protein interactions | 10095 | 47 | 14 | 16036 | 2270 |
METTL1,TPD52L2,UBE3A,ACTR3,RANGAP1,NT5C,ANP32B,AARS,ACTR3B,IPO11,PRKACB,SRPK2,ARPC3,TOM1L1 |
| 4.350e-03 | -5.44 | PPME1 (protein phosphatase methylesterase 1) | protein interactions | 51400 | 47 | 14 | 16036 | 2270 |
P3H1,SURF2,ALAD,TSTA3,CAMK1,XPO5,HK2,GPN1,LRSAM1,RPA1,NUDC,TJAP1,TOM1L1,LPP |
| 4.375e-03 | -5.43 | regulation of embryonic development | biological process | GO:0045995 | 112 | 25 | 16441 | 2138 |
LAMA4,PHLDB2,MAP2K5,COL5A2,CELSR1,PAFAH1B1,FZD3,WDPCP,GRHL3,MKS1,LAMA2,RBM19,PLCB1,PHLDA2,KDM1A,FGFR1,WNT2B,DKK1,KLF4,BMP4,NOCT,AMOT,LAMA5,PRKACB,STK4 |
| 4.380e-03 | -5.43 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | MSigDB lists | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | 22 | 8 | 17758 | 2279 |
BRCA2,TP53BP1,H2AFX,ATM,LIG4,BRCA1,XRCC4,RPA1 |
| 4.380e-03 | -5.43 | DALESSIO_TSA_RESPONSE | MSigDB lists | DALESSIO_TSA_RESPONSE | 22 | 8 | 17758 | 2279 |
STXBP6,TEX14,LGALS1,HSPB8,CLU,ARC,FOSL2,ANXA1 |
| 4.390e-03 | -5.43 | GTF2F1 (general transcription factor IIF subunit 1) | protein interactions | 2962 | 77 | 20 | 16036 | 2270 |
TAF1,SF3A3,CSNK2A1,ATF7IP,BRCA1,CDC73,POLR2A,ABL1,MSX2,DUS3L,GTF2A1,CCNT1,MYC,CDK9,HIRIP3,GTF2H1,PUS1,PSAP,PRPS1,SF3A1 |
| 4.399e-03 | -5.43 | NA-bd_OB-fold | interpro domains | IPR012340 | 79 | 19 | 18293 | 2341 |
NARS2,EXOSC2,MCM6,LIN28B,SUPT6H,NARS,LIG4,MCM2,MCM9,RPA1,BRCA2,SRBD1,MCM5,EIF2S1,SSBP1,YBX3,PDCD11,YARS,DIS3L2 |
| 4.433e-03 | -5.42 | TATTATA,MIR-374 | MSigDB lists | TATTATA,MIR-374 | 276 | 51 | 17758 | 2279 |
HERC2,TCF12,FOXO1,ARID2,ARL15,PDE4B,RSF1,BHLHE40,FOXP1,CHD7,FKBP1A,EIF2S2,MLX,HR,MMP14,WNT16,LARP4B,PKNOX1,SRPK2,ZCCHC14,PCGF3,MSX1,GPM6A,CRIM1,SKIV2L2,SMARCAD1,SETD2,ATXN1,MEX3B,CAMSAP2,PRDM1,MEF2D,ATP8B2,SOX4,DENND4A,SYT1,MBNL2,RAB10,MKX,FAM135A,LRP1B,GADD45A,PMEPA1,LEMD3,ZNF236,SOCS4,IQSEC2,NR2F2,MAP2K4,RNF214,TNRC6A |
| 4.447e-03 | -5.42 | core promoter sequence-specific DNA binding | molecular function | GO:0001046 | 94 | 22 | 16491 | 2164 |
ATF4,EGR1,RREB1,PPARG,BAZ2A,SMARCA4,SOX4,TCF7L2,SMARCB1,UBTF,RRN3,NRF1,NSD1,GATA6,ZFHX3,CHD2,RBPJ,PRMT5,NRIP1,KMT2A,SMYD3,TOP1 |
| 4.460e-03 | -5.41 | GSE17721_LPS_VS_POLYIC_4H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_4H_BMDM_DN | 193 | 38 | 17758 | 2279 |
TCF12,FEZ2,CELSR1,DDX18,HES6,VARS,ST7L,XPO7,AHCYL2,FRRS1,DCTPP1,FAM50A,ANKRD13A,CAMTA2,BCAS2,TRIAP1,LPIN2,NT5M,TMEM14C,PRPS1,C12orf4,POLK,GNL3,LDHA,GMFB,MEF2D,CPT1A,EIF3H,MGST1,KLF4,DNAJA3,H2AFX,GPN1,SLC25A11,PKIB,TNRC6A,NR2C2AP,TMEM141 |
| 4.460e-03 | -5.41 | GSE29618_PDC_VS_MDC_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DN | 193 | 38 | 17758 | 2279 |
SERINC5,PSTPIP2,PID1,ID2,ZFP36L1,AP1B1,CSTA,CD226,NAMPT,RTN1,SPG21,S100A10,ASAP1,ATG3,ANXA5,PTGS1,ITGAX,PPA1,EVL,TUBA1A,RAB7A,LGALS1,RNH1,PTPN12,COTL1,IL6R,ANXA1,VDR,FBXL5,PDLIM1,HIF1A,HK2,ANXA2,TBL1X,APAF1,RBPJ,PTP4A2,IFITM2 |
| 4.460e-03 | -5.41 | GSE17721_0.5H_VS_4H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDM_UP | 193 | 38 | 17758 | 2279 |
ZNF706,NCOR2,WDR75,ADAM19,TTC27,DDX18,LAGE3,SSBP2,TGFBR2,AHCYL2,IQGAP2,SKI,ABL1,BCAS2,ATG3,NCKIPSD,PTGS1,ADCK4,LYRM5,SLC35C2,TIMM50,SRPK2,MTHFD1,VOPP1,CDK4,GNL3,PPP1R21,TPRA1,ANGPTL4,VPS53,TIMM44,RPA1,KLHL22,SURF1,CDKAL1,SENP3,TXN2,HS2ST1 |
| 4.460e-03 | -5.41 | GSE17721_LPS_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_8H_BMDM_DN | 193 | 38 | 17758 | 2279 |
SEPHS2,ATP6V1A,MYO7A,LIAS,GFM2,NOP56,FKBP1A,COMMD9,FAM50A,NPRL2,SLC38A5,SURF2,NOP16,MYC,PPCDC,KDM5C,TSPAN14,WDR36,PXN,GARS,WDFY3,PPARG,XPO5,MED27,TBXAS1,MINA,SUMO3,GALK2,TARS,HERPUD1,TMEM186,CAT,ETFDH,AEN,SLC25A11,RPS6KB1,BPNT1,MED20 |
| 4.460e-03 | -5.41 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 193 | 38 | 17758 | 2279 |
JUP,UBN1,ISG20L2,PRKCA,EEA1,TADA3,FARSA,BRE,SREBF2,BANF1,NISCH,PMPCA,VPS52,MED24,SHMT2,PCK2,ITGAX,FBL,YARS,RPS6KB2,ATF4,GARS,CAMKK2,TSTA3,TEAD1,PCCA,ATP6V0A1,MARS,STK10,NEU1,MFN2,HLA-DMA,ETFDH,TPD52L2,TRAF3,COPS6,KDM4C,MEF2C |
| 4.465e-03 | -5.41 | adamantinomatous | COSMIC cancer mutations | adamantinomatous | 362 | 64 | 17775 | 2278 |
DMXL2,TBKBP1,ABCA3,PCNT,ARID2,RARS2,FANCD2,SMARCA4,RSL1D1,ZNF107,ZNF83,BCOR,PELP1,SKI,RTN1,DHX33,NT5C,CHD2,ETF1,ZNF3,CASP8AP2,CSGALNACT2,FMNL3,ATG9A,ALDH1L2,ARHGEF10,LAMA2,SON,ZNF91,DDX60,UBR4,DHX57,RBBP8,BRCA2,TRRAP,ZNF598,PARD3,BRAF,ITPRIP,RFX1,WDR37,QSER1,USPL1,NISCH,UNC13A,DDX31,ACTR3B,HMGCR,ZNF675,SLC40A1,KDM5A,PRDM16,KCNMA1,OBSCN,RSBN1,PHACTR2,MAP7D1,C8orf33,MBNL2,TBC1D2,ZNF708,DNAH17,ZNF430,ARHGAP12 |
| 4.465e-03 | -5.41 | pituitary-craniopharyngeal_duct-craniopharyngioma-adamantinomatous | COSMIC cancer mutations | pituitary-craniopharyngeal_duct-craniopharyngioma-adamantinomatous | 362 | 64 | 17775 | 2278 |
DMXL2,TBKBP1,ABCA3,PCNT,ARID2,RARS2,FANCD2,SMARCA4,RSL1D1,ZNF107,ZNF83,BCOR,PELP1,SKI,RTN1,DHX33,NT5C,CHD2,ETF1,ZNF3,CASP8AP2,CSGALNACT2,FMNL3,ATG9A,ALDH1L2,ARHGEF10,LAMA2,SON,ZNF91,DDX60,UBR4,DHX57,RBBP8,BRCA2,TRRAP,ZNF598,PARD3,BRAF,ITPRIP,RFX1,WDR37,QSER1,USPL1,NISCH,UNC13A,DDX31,ACTR3B,HMGCR,ZNF675,SLC40A1,KDM5A,PRDM16,KCNMA1,OBSCN,RSBN1,PHACTR2,MAP7D1,C8orf33,MBNL2,TBC1D2,ZNF708,DNAH17,ZNF430,ARHGAP12 |
| 4.466e-03 | -5.41 | MCMFAMILY | prints domains | PR01657 | 8 | 4 | 4759 | 462 |
MCM6,MCM2,MCM5,MCM9 |
| 4.499e-03 | -5.40 | Alpha6-Beta4 Integrin Signaling Pathway | WikiPathways | WP244 | 69 | 17 | 4455 | 564 |
COL17A1,LAMC1,VIM,PTK2,LAMA2,PRKCA,DSP,PIK3CB,DST,IRS1,SMAD3,ABL1,MMP7,SHC1,ITGB4,MET,LAMA5 |
| 4.504e-03 | -5.40 | CDC6 (cell division cycle 6) | protein interactions | 990 | 52 | 15 | 16036 | 2270 |
MCM10,AKAP8L,UBR1,POLA1,E2F4,MYC,CDK4,ORC5,ATM,ATRIP,MCM2,UBE2K,TGFBR2,BMI1,CDK6 |
| 4.504e-03 | -5.40 | RNF20 (ring finger protein 20, E3 ubiquitin protein ligase) | protein interactions | 56254 | 52 | 15 | 16036 | 2270 |
PAF1,RNF40,PMS1,SUPT6H,SIRT6,UCHL5,CDK9,WAC,XPNPEP1,ATM,CDC73,UBC,CIAPIN1,UBE2E1,USP15 |
| 4.504e-03 | -5.40 | AARS (alanyl-tRNA synthetase) | protein interactions | 16 | 52 | 15 | 16036 | 2270 |
METTL1,TPD52L2,GARS,ASNS,FN1,NARS,ANKMY2,SIRT7,NMD3,ISG15,SBDS,CIAPIN1,IPO11,WARS,TOM1L1 |
| 4.504e-03 | -5.40 | RSL1D1 (ribosomal L1 domain containing 1) | protein interactions | 26156 | 52 | 15 | 16036 | 2270 |
SNU13,NIFK,CUL7,MYBBP1A,FN1,COPS5,SIRT7,CSNK2A1,RNF2,BRCA1,FBL,NOLC1,NOP58,ZC3H3,NOP56 |
| 4.511e-03 | -5.40 | purine ribonucleotide metabolic process | biological process | GO:0009150 | 305 | 56 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,NDUFB5,PDE4B,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,PDE3A,NDUFB3,AMPD3,GART,NDUFV1,ENTPD5,ATP5G2,PDE10A,ATIC,PPCDC,MYH3,NDUFA6,FXN,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,PDE4A,PPAT,ITPA,SULT4A1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,PDE2A,PDE3B,HSPA1B,PDE8B,SNCA,STOML2,ATP5D,HPRT1,NME7,COQ9,HK2,SURF1,NDUFS5,BPNT1,ADK,PDE9A |
| 4.512e-03 | -5.40 | Metabolism | REACTOME pathways | R-HSA-1430728 | 1691 | 264 | 8202 | 1117 |
GGT1,GNB3,PRKAB2,TNFRSF21,GYG1,NT5C3A,PRKCA,SLC6A8,HMOX2,SYNJ1,NUP160,LPIN1,CIAPIN1,SREBF2,ATP5G2,FAAH2,SUCLG2,ME1,FXN,PPM1K,SEH1L,CSGALNACT2,ACADS,UPP1,GNG7,GNAI1,PYCR1,DDAH2,BDH2,PIK3R4,PLA2G12A,NDUFS7,PI4KB,CACNB2,ATIC,MED24,LPCAT1,AGL,COQ3,PRPS1,FDFT1,HMGCR,FADS1,PCCA,AOC2,IDH3G,RAPGEF4,SMARCD3,IMPDH2,SNAP25,PLCB1,CPT1A,ANGPTL4,MTR,CAT,GSTO2,VCAN,D2HGDH,MED15,SURF1,SQLE,DPEP1,UMPS,BPNT1,NCOR1,CNDP2,DHCR7,HS2ST1,GALE,NPAS2,PDK4,UROD,NDUFB5,NUP43,ST3GAL6,LCLAT1,NDUFB3,FLAD1,DECR1,ASNS,PYCRL,LPIN2,GSTA4,NT5C,CMPK1,MGLL,PDK1,MED16,SLC35D1,NUDT15,MAT2A,HSD3B7,GNG2,DCXR,G6PD,PEMT,NCOR2,NOSTRIN,INSIG2,B4GALT5,MRI1,SLC25A12,IP6K2,INPP1,PSMF1,POM121,ACOT11,PHYKPL,PTGS1,NT5M,MBTPS2,PFKFB4,PSAT1,AGPAT4,LDHA,ADSL,PPIP5K2,MMAA,UBC,SLC23A2,TRIB3,ETFDH,NME1-NME2,STX1A,ACOX1,SRD5A3,NDUFS5,GPAM,PSAP,ADK,MTMR1,CYP24A1,SRM,LYRM4,MVK,SLC52A3,PPARGC1B,SLC25A21,CERS5,COX10,AMPD3,RAP1A,PHKA1,PPCDC,HYAL1,RAN,SLC27A5,NDUFA6,CARM1,PRKACB,CHD9,ITPA,PPARG,MED27,GPCPD1,COL4A3BP,MTHFD1L,PITPNB,CAV1,DLST,ODC1,MPC1,MGST1,GLS,HPRT1,LSS,INSIG1,HLCS,ABCC3,XYLB,AOC3,CHST11,AK2,SEC24D,PRSS3,GPAT3,HSD17B10,MED13L,PHGDH,ETFB,NAMPT,MLX,VAPB,GLTP,SYNJ2,PNPLA3,ALDH18A1,MTHFD1,NT5E,PPAT,ELOVL6,TBXAS1,PSMA1,VAC14,PGD,FDPS,HK2,SLC16A1,TBL1X,HMBS,GGT7,PRKAR2A,PDSS2,SUCLG1,NDUFAF2,SLC5A5,CEMIP,LPCAT2,SLC2A1,LPCAT3,ARSJ,FDX1,CAD,NRF1,IDI1,NUP133,HIBCH,AHCYL1,GNG5,TMLHE,SEC24A,MCEE,ACSL5,CPOX,CA5B,NUP214,ATP5D,TPK1,PLIN2,RANBP2,HYAL3,ALAD,ARNTL,ABHD3,SLC25A11,SCARB1,MED20,BCKDK,AUH,SULT1C2,TKFC,APRT,MED18,PIP4K2A,SLC25A20,ADH5,GART,NDUFV1,HAS3,SEC24C,SHMT2,CPNE7,CD44,PCK2,HSD17B12,SLC25A1,GPHN,TEAD1,SULT4A1,PIK3CB,NEU1,GPC2,NDUFAF5,GCSH |
| 4.530e-03 | -5.40 | V$AP1_Q6 | MSigDB lists | V$AP1_Q6 | 244 | 46 | 17758 | 2279 |
TCF12,PTP4A1,RELL2,FAM46B,RTN4,AKT1S1,SPATS2,TGFBR2,PHLDA2,MMP7,ECM1,CCDC50,ANXA7,NEK6,VGF,ADCK4,PEA15,FLNC,LAMC1,WDFY3,TEX19,RB1CC1,BAZ2A,EIF3J,TOR1AIP2,VIM,ZNFX1,PRDM1,SLC9A5,NCDN,GNAI1,YIF1A,VDR,DYNC1H1,GADD45A,POLR3E,ZNF436,HSPB8,TRAF3,DIRAS1,RBPJ,NFRKB,BLMH,RAB30,ATXN7L2,LPP |
| 4.530e-03 | -5.40 | RICKMAN_METASTASIS_DN | MSigDB lists | RICKMAN_METASTASIS_DN | 244 | 46 | 17758 | 2279 |
CDCP1,JUP,BTBD2,SPRYD7,ACTR3,SLC2A1,PCSK7,FOSL2,SLC6A8,MTUS1,DST,FARSA,AMPD3,NAV1,TBC1D22A,UBAP2L,RDX,S100A14,CD44,TSPAN14,PRF1,DENND1A,PERP,CARM1,HN1,DSC3,MALL,CAMKK2,C19orf43,TPM4,LRRC8A,RNH1,SEMA3F,ARHGEF12,MEF2D,MEGF11,S100A16,SH3GL1,ATP5D,TBC1D2,CAMK2D,PDLIM1,TOM1L2,AHNAK2,ITGB4,WDR66 |
| 4.553e-03 | -5.39 | SNRNP200 (small nuclear ribonucleoprotein, U5 200kDa subunit) | protein interactions | 23020 | 142 | 32 | 16036 | 2270 |
SART1,CUL7,FN1,PRPF31,SIRT7,SF3A3,PDCD7,SNW1,BCAS2,MYC,RNF2,SRRM2,PABPC1,TOP1,PRPF19,SF3A1,SIRT6,ELP3,WDHD1,BRCA1,CPT1A,UBR4,PHF6,ISG15,RPA1,RANBP2,HNRNPR,COPS5,CUL2,IRAK2,PRPF4,YEATS2 |
| 4.564e-03 | -5.39 | HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2) | protein interactions | 8924 | 67 | 18 | 16036 | 2270 |
HERC2,PMS1,BIRC6,SIRT7,USP42,RIPK1,BRCA1,STK33,UBC,RPA1,FBXL5,UBE3A,UCHL5,TANK,ATRIP,USP20,RABEP1,CEP170 |
| 4.566e-03 | -5.39 | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | MSigDB lists | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | 102 | 23 | 17758 | 2279 |
RFC3,PRIM2,ELOVL6,TCF3,AKAP12,SMARCA4,WDHD1,CHCHD10,PDE2A,FKBP3,SMARCB1,IGF2BP3,GEMIN5,HPRT1,SRSF2,CDK9,RNF2,PLEKHA2,BLMH,MUTYH,ELOF1,MYB,MTHFD1 |
| 4.566e-03 | -5.39 | REACTOME_DNA_REPAIR | MSigDB lists | REACTOME_DNA_REPAIR | 102 | 23 | 17758 | 2279 |
RFC4,POLB,GTF2H3,RFC3,APEX1,XPC,FANCD2,LIG4,BRCA1,POLR2A,MAD2L2,RPA1,BRCA2,ALKBH3,POLE2,PALB2,TP53BP1,H2AFX,ATM,GTF2H1,XRCC4,OGG1,MUTYH |
| 4.569e-03 | -5.39 | PRC2_EDD_UP.V1_UP | MSigDB lists | PRC2_EDD_UP.V1_UP | 187 | 37 | 17758 | 2279 |
BCKDK,MCM10,JUP,BTBD2,RIPK1,VARS,FOSL2,MFHAS1,PLXNB1,CAD,SURF2,MCM5,ZDHHC6,NDRG4,WIZ,DDX31,CORO1A,SLC35C2,PNPLA3,PFKFB4,LRRC20,EXOSC2,TNK2,FBXO17,RANGAP1,PACS1,MCM2,PEAK1,SYMPK,VAC14,LSS,INSIG1,EHMT2,TRMT2A,USP20,FKBP5,TNFRSF10D |
| 4.569e-03 | -5.39 | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_DN | 187 | 37 | 17758 | 2279 |
NCOR2,FN1,CERS5,CMTM3,REEP5,MFSD10,NEDD4,PABPC4,PRKCH,ADH5,RPS16,SREBF2,COPS3,ANXA5,PTGS1,RAN,POLR1E,HSD17B12,PEA15,FAM98A,METTL1,CRIM1,IDH3G,TBRG4,MARCH6,STK10,ARIH2,ZC3H12A,GNG2,ARHGAP21,AHNAK,HLCS,AEN,USP20,ARHGAP12,ABCC3,CHMP4C |
| 4.571e-03 | -5.39 | CSR_EARLY_UP.V1_UP | MSigDB lists | CSR_EARLY_UP.V1_UP | 156 | 32 | 17758 | 2279 |
PTP4A1,PAPD4,VTA1,ACTR3,SMAD7,SMARCA4,PCSK7,GABPB2,POM121,MAP2K3,ELL,DHX33,NOP16,POLE3,NRIP1,TMEM200A,NT5E,TOP1,SEC24A,TRNP1,PXN,TCEB3,LRRC8A,PTPN12,DKC1,DSP,USP36,DOT1L,ZBTB12,SLC16A1,DLX2,NMD3 |
| 4.581e-03 | -5.39 | NLK (nemo-like kinase) | protein interactions | 51701 | 57 | 16 | 16036 | 2270 |
FBXW4,FOXO1,ZHX3,TLE3,RCHY1,ATXN1,RANGAP1,TNKS1BP1,FOXO3,TCF7L2,SKI,RANBP2,FAM222B,HIPK2,UBAP2L,MYB |
| 4.581e-03 | -5.39 | ASH2L (ash2 (absent, small, or homeotic)-like (Drosophila)) | protein interactions | 9070 | 57 | 16 | 16036 | 2270 |
KDM6B,KMT2D,SETD1B,PPARG,BRCA1,MEF2D,KMT2C,MEN1,CDC73,KDM4B,E2F4,SENP3,HCFC2,KMT2A,MYB,EMSY |
| 4.587e-03 | -5.38 | TINF2 (TERF1 (TRF1)-interacting nuclear factor 2) | protein interactions | 26277 | 93 | 23 | 16036 | 2270 |
VIPR1,DBN1,SARS,SULT1C2,STAG1,TRIM16,ANKMY2,LDHA,TRIM15,ZFP36L1,NOL3,MAP2K3,NCDN,TERF2IP,ACD,ARID3B,HOXA3,PAK1IP1,ANXA5,TBL1X,TOMM34,TERF2,NUDC |
| 4.596e-03 | -5.38 | MULLIGHAN_MLL_SIGNATURE_2_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_DN | 270 | 50 | 17758 | 2279 |
LUZP1,TRIM16,ATRX,TNFRSF21,KHDRBS1,TCF3,OLA1,BARX2,AP1B1,TGFBR2,UBR5,STAM,NEDD4,MAN1A1,PRKCH,CD96,PTRF,PMAIP1,TTC3,ZNF85,PRF1,HSD17B12,FDFT1,NAV3,DBN1,KDM5B,ABCC4,TFPI,PITPNB,SERP1,UBE2E1,FGFR1,PYCR1,GLS,SLC7A1,RANBP2,SYNCRIP,HIF1A,FSCN1,DNAJC12,DNAH2,RUNX1,TBXA2R,NR2F2,ADK,CEP170,LAMA5,PTPN14,N4BP2L2,HS2ST1 |
| 4.596e-03 | -5.38 | LU_EZH2_TARGETS_UP | MSigDB lists | LU_EZH2_TARGETS_UP | 270 | 50 | 17758 | 2279 |
BCAS4,TRIP6,WDR74,H2AFJ,PPP2R2A,DPM3,PHGDH,C1orf50,REEP5,C15orf57,RPAIN,ETFB,DDIT4,C6orf48,PHF5A,SURF2,PPFIBP1,PCK2,LPCAT1,OGG1,LONP1,RPS6KB2,ZNF629,VOPP1,TLCD1,FAM71E1,PRIM2,IFT43,TEX19,ATOX1,TPM4,TMEM216,MSRB3,OASL,KRTCAP2,PUSL1,ISG15,ARHGAP21,TRIB3,HYAL3,SERF2,HSDL2,CDK9,CFD,AHNAK2,NOLC1,SLC25A26,ZNF589,DDIT3,TMEM141 |
| 4.597e-03 | -5.38 | DHX8 (DEAH (Asp-Glu-Ala-His) box polypeptide 8) | protein interactions | 1659 | 62 | 17 | 16036 | 2270 |
SIRT7,RSL1D1,JMJD6,RBM28,SAP30BP,AHCYL2,SMAD3,SNW1,PHF5A,KANSL1,SHMT2,POLR1B,AHCYL1,FTSJ3,SRPK2,PRPF19,MORC2 |
| 4.597e-03 | -5.38 | SLAMF1 (signaling lymphocytic activation molecule family member 1) | protein interactions | 6504 | 62 | 17 | 16036 | 2270 |
ZNF292,PTCD2,NF1,URB2,LGALS1,SLC1A1,MAD2L2,SLC39A11,TAMM41,ANKRD13A,INTS7,INTS12,LTN1,VPS52,HEATR1,NR2F2,MTCH1 |
| 4.597e-03 | -5.38 | THAP7 (THAP domain containing 7) | protein interactions | 80764 | 62 | 17 | 16036 | 2270 |
ASH1L,DDX24,TFIP11,CCNDBP1,NLE1,PUM3,NOP56,GNAI1,PHC2,EXOC1,EHMT2,CEBPZ,SET,CCDC85B,C7orf50,PPP3CC,NCOR1 |
| 4.609e-03 | -5.38 | VIM (vimentin) | protein interactions | 7431 | 228 | 47 | 16036 | 2270 |
THOC5,FN1,TRIM16,UTP14A,RIBC2,UROD,PPHLN1,CEP126,BHLHE40,TOX4,ANXA7,RNF2,SERPINH1,CWF19L2,SRRM2,HTRA2,SERBP1,DIS3L2,SPTAN1,KRT20,OSBP2,SIRT6,UPP1,KIF15,PSMA1,SUMO3,VIM,RABAC1,MEN1,DSP,UBR4,ISG15,SH3GL1,RPA1,SMAD3,CAMK2D,GADD45A,PDLIM1,STX1A,CHD3,COPS5,SVIL,COPS6,ITGB4,POLR1C,TXN2,XRCC4 |
| 4.611e-03 | -5.38 | - | gene3d domains | 2.60.120.260 | 73 | 19 | 9988 | 1398 |
HERC2,MYCBP2,FBXO17,CUL7,LAMC1,CNTNAP3,MFGE8,HECTD3,DDR2,PCSK7,BTBD9,LAMA2,DCBLD2,ZZEF1,ANAPC10,NRP1,CNTNAP3B,NR2C2AP,PCSK6 |
| 4.630e-03 | -5.38 | CTCTGGA,MIR-520A,MIR-525 | MSigDB lists | CTCTGGA,MIR-520A,MIR-525 | 150 | 31 | 17758 | 2279 |
YDJC,TSHZ1,NCOR2,CGN,PPP1R9B,SNX27,CDCP1,FN1,PAFAH1B1,PSMC3IP,ALG8,NHS,ATXN1,SATB2,RSBN1,PRDM1,METTL22,SON,POGZ,ZNF655,BSN,ABL1,NSD1,TCF7L1,TSPAN2,IKZF4,THADA,GTF2H1,RAPGEFL1,SEH1L,SMG1 |
| 4.648e-03 | -5.37 | LAIHO_COLORECTAL_CANCER_SERRATED_UP | MSigDB lists | LAIHO_COLORECTAL_CANCER_SERRATED_UP | 108 | 24 | 17758 | 2279 |
SEC24A,LAMC1,LGALS1,NXN,CAV1,MON2,PALLD,CSNK1A1,DDX60,CLINT1,EPRS,SPG21,PXDN,SERF2,HIF1A,PAM,ANXA5,SVIL,SELT,BCAP29,ANXA2,PDLIM5,TROVE2,SRP14 |
| 4.675e-03 | -5.37 | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP | 181 | 36 | 17758 | 2279 |
USP7,BCKDK,ID1,DBF4,CENPB,ST7L,PITPNM1,RING1,PHC2,CAD,KDM2A,IKZF5,PVRL3,FMNL1,PYCRL,MAD1L1,RELB,ZFP37,ZNF148,NAA35,RPS6KB2,BRD4,KRT7,TSTA3,ITPA,PSMC3IP,ZNF512B,TPM4,MEF2D,TPRA1,ZBTB25,IFT81,APBB3,TTC38,USP11,SMG1 |
| 4.675e-03 | -5.37 | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | 181 | 36 | 17758 | 2279 |
RTTN,XPC,HMOX2,PELP1,PAG1,PRKCH,CD96,ATIC,FAAH2,MAP3K14,FBXO31,PRPS1,PNMA1,SPTAN1,VOPP1,EVL,DDX24,TSPYL4,ZNF512B,KIAA0586,PCNXL2,PHACTR2,ZNFX1,MTHFD1L,ATP8B2,EIF5B,SLC26A11,ZBTB25,TAF9B,MKL2,USP20,ZFP90,PPP3CC,NFRKB,SPOCK2,RNF214 |
| 4.675e-03 | -5.37 | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 181 | 36 | 17758 | 2279 |
C9orf78,FOXO1,ITPRIP,BCOR,CHD7,SRSF2,IKZF5,USPL1,CHD2,KIAA0922,NRIP1,MTHFD2L,CDK12,SF3A1,PXN,RB1CC1,JMJD1C,SETD2,NOL8,CUX1,TCEB3,MAPK1IP1L,SLC35D1,SOX4,NUP214,TCF7L2,ANXA1,DDX3X,NAP1L5,NSD1,LSM14A,HIF1A,ZZEF1,CSRNP1,RPS6KB1,BRD9 |
| 4.681e-03 | -5.36 | mitochondrial respiratory chain complex assembly | biological process | GO:0033108 | 36 | 11 | 16441 | 2138 |
IMMP2L,NUBPL,AARS2,BCS1L,NDUFAF5,NDUFS5,UQCC2,UQCC1,FOXRED1,COA1,NDUFS7 |
| 4.705e-03 | -5.36 | DNA-directed RNA polymerase III complex | cellular component | GO:0005666 | 18 | 7 | 17570 | 2233 |
CRCP,POLR3D,POLR3B,POLR1C,POLR3A,POLR3E,POLR3G |
| 4.705e-03 | -5.36 | small nucleolar ribonucleoprotein complex | cellular component | GO:0005732 | 18 | 7 | 17570 | 2233 |
POP1,SNU13,MPHOSPH10,FBL,DKC1,NOP58,NOP56 |
| 4.717e-03 | -5.36 | JMJN | prosite domains | PS51183 | 10 | 5 | 11866 | 1504 |
KDM5C,KDM5B,KDM4B,KDM5A,KDM4C |
| 4.730e-03 | -5.35 | ZNF394 (zinc finger protein 394) | protein interactions | 84124 | 6 | 4 | 16036 | 2270 |
USP7,CCNDBP1,ZNF397,CLK2 |
| 4.730e-03 | -5.35 | DHRS4L2 (dehydrogenase/reductase (SDR family) member 4 like 2) | protein interactions | 317749 | 6 | 4 | 16036 | 2270 |
MTIF2,ZZEF1,D2HGDH,AARS2 |
| 4.730e-03 | -5.35 | HELZ2 (helicase with zinc finger 2, transcriptional coactivator) | protein interactions | 85441 | 6 | 4 | 16036 | 2270 |
PPARG,BMI1,SIRT7,ISG15 |
| 4.730e-03 | -5.35 | SCML2 (sex comb on midleg-like 2 (Drosophila)) | protein interactions | 10389 | 6 | 4 | 16036 | 2270 |
PHC2,USP7,RNF2,BAG1 |
| 4.730e-03 | -5.35 | RNF214 (ring finger protein 214) | protein interactions | 257160 | 6 | 4 | 16036 | 2270 |
TRIP6,IGBP1,PLPPR2,LAGE3 |
| 4.749e-03 | -5.35 | PAL_PRMT5_TARGETS_UP | MSigDB lists | PAL_PRMT5_TARGETS_UP | 200 | 39 | 17758 | 2279 |
RARS2,LAGE3,SF3A3,ID2,PCDH7,COPS3,CFDP1,ANP32B,MET,TRIP13,CARM1,CASP8AP2,HN1,ELOF1,PTPRK,TMPO,EVL,PRIM2,APEX1,CDK4,WLS,HAUS6,MCM2,ODC1,CPT1A,NOP58,ECH1,NR2F1,EHMT2,POLE2,VCAN,LUC7L3,SET,H2AFX,NCBP2,DTD1,NR2F2,IGBP1,IPO4 |
| 4.759e-03 | -5.35 | KMCATNNWGGA_UNKNOWN | MSigDB lists | KMCATNNWGGA_UNKNOWN | 85 | 20 | 17758 | 2279 |
TSHZ1,SPRED2,MAP2K5,AEBP2,STAG1,CELSR3,CUX1,ENAH,CSNK1A1,GBF1,SCAF8,NR2F1,ABL1,SYNCRIP,CWC27,ARNTL,HIC2,GEMIN4,NR2F2,ZBTB11 |
| 4.760e-03 | -5.35 | ZHENG_BOUND_BY_FOXP3 | MSigDB lists | ZHENG_BOUND_BY_FOXP3 | 470 | 80 | 17758 | 2279 |
TCF12,ADAM19,FEM1C,ACTR3,COBLL1,TBCCD1,TUBE1,ADAMTS6,PAG1,SLC30A7,CHD7,CD96,ZNF608,RAP1A,THADA,RABGAP1L,ANKRD11,CHD2,PTPRK,EXOC6B,CPOX,ARHGEF10,AKAP13,STK10,SNCA,ZBTB25,SMAD3,GNG2,TMCO1,ARL4A,NSMCE2,NSMCE1,INTS9,PPP3CC,BEND6,NRP1,LRCH1,BANP,SSH2,IFT57,ST6GAL1,PDE4B,MYNN,WDR37,TGFBR2,FOXP1,ENOX1,CD226,PIP4K2A,MBNL1,BZW2,MAN1A1,PRKCH,CWC27,CD44,AMOT,NRIP1,C12orf4,NT5E,VOPP1,SIK3,GPHN,CRADD,JMJD1C,ARID5B,EPS15L1,PSMA1,PRDM1,ARID1A,CORIN,KLF6,EVI5,SLC23A2,ANXA1,ATXN7,TASP1,HIF1A,L3MBTL3,WDR35,VPS37B |
| 4.761e-03 | -5.35 | WD40_repeat_CS | interpro domains | IPR019775 | 163 | 33 | 18293 | 2341 |
GNB3,PAFAH1B1,PLRG1,PIK3R4,WDR37,NUP43,CORO6,DENND3,NLE1,AMBRA1,PEX7,PAK1IP1,CORO1A,LYST,PRPF19,WDR36,WDR61,WDFY3,TLE3,WDR18,UTP15,WDHD1,PWP1,GEMIN5,WDR5B,HERC1,WDR7,TSSC1,PRPF4,APAF1,TBL1X,BRWD3,CORO2B |
| 4.765e-03 | -5.35 | KOYAMA_SEMA3B_TARGETS_UP | MSigDB lists | KOYAMA_SEMA3B_TARGETS_UP | 264 | 49 | 17758 | 2279 |
CDCP1,NPAS2,CNTNAP3,OPHN1,KIF5C,TUBE1,CHAC1,LPAR3,DDIT4,SIPA1L3,UBE3A,IKZF5,SETD5,STC2,DYNC2H1,CELF1,TTC17,CD44,GMDS,FMNL2,TMEM200A,HSD17B14,ZNF629,FBXW4,RREB1,SLC38A1,KCNMA1,TMEM216,RABAC1,SUPT5H,SYT1,MGST1,POLR3A,DCBLD2,KIF16B,ANXA1,TBC1D2,PAF1,SUFU,DAGLB,LSM14A,KIAA0355,HK2,BDH2,TMEM117,C7orf50,BRCC3,MID1,N4BP2L2 |
| 4.776e-03 | -5.34 | human chr13q32 | chromosome location | human chr13q32 | 8 | 4 | 26250 | 2590 |
ZIC2,ABCC4,CLYBL,PCCA |
| 4.778e-03 | -5.34 | MODULE_126 | MSigDB lists | MODULE_126 | 175 | 35 | 17758 | 2279 |
ACTG1,CAMK1,TNFRSF21,TCF3,DBF4,CD99L2,CSNK2A1,DENND3,HDDC2,GART,NEK6,MYC,SHMT2,RAN,MGLL,ANGPT2,MYB,RFC4,RFC3,IFNGR2,APEX1,TUBA1A,ITPA,PPAT,CDK4,HSPA5,ADSL,IMPDH2,ODC1,TIMM44,ZFAND3,UMPS,ADK,BLMH,NOLC1 |
| 4.780e-03 | -5.34 | Activation of the pre-replicative complex | REACTOME pathways | R-HSA-68962 | 30 | 10 | 8202 | 1117 |
MCM6,MCM10,POLE2,PRIM2,POLA1,MCM5,ORC5,DBF4,MCM2,RPA1 |
| 4.781e-03 | -5.34 | PNKD (paroxysmal nonkinesigenic dyskinesia) | protein interactions | 25953 | 88 | 22 | 16036 | 2270 |
RANBP6,STAG1,GON4L,TFIP11,CAMK1,DYM,EIF3J,PPARGC1B,DCUN1D5,AP1B1,RADIL,NUP160,GBF1,LSS,PPFIBP1,ATRIP,TAF12,EIF2B3,ARL14EP,RTFDC1,IPO11,FDFT1 |
| 4.787e-03 | -5.34 | KAT8 (K(lysine) acetyltransferase 8) | protein interactions | 84148 | 38 | 12 | 16036 | 2270 |
PAF1,KAT8,DYRK1B,TNK2,BRD4,BAZ2A,KANSL1,TCEB3,H2AFX,ATM,RNF2,KMT2A |
| 4.836e-03 | -5.33 | cardiac ventricle morphogenesis | biological process | GO:0003208 | 62 | 16 | 16441 | 2138 |
TNNC1,PTCD2,DLL4,SMAD7,SMARCD3,RYR2,SOX4,DSP,FOXC1,FKBP1A,JAG1,HIF1A,SEMA3C,RBPJ,TPM1,MEF2C |
| 4.836e-03 | -5.33 | global genome nucleotide-excision repair | biological process | GO:0070911 | 62 | 16 | 16441 | 2138 |
GTF2H3,RFC4,RFC3,CUL4A,XPC,POLK,SUMO3,UBC,RPA1,COPS4,COPS5,COPS3,RNF111,GTF2H1,COPS7B,COPS6 |
| 4.852e-03 | -5.33 | ZC3H15 (zinc finger CCCH-type containing 15) | protein interactions | 55854 | 29 | 10 | 16036 | 2270 |
THOC5,GINS3,WDR74,ZCCHC8,ABCF2,CSNK2A1,RNF2,PPIP5K2,C8orf33,ISG15 |
| 4.852e-03 | -5.33 | CSTF1 (cleavage stimulation factor, 3' pre-RNA, subunit 1) | protein interactions | 1477 | 29 | 10 | 16036 | 2270 |
ASNS,TTC27,PAFAH1B1,BRCA1,PARN,BMI1,NMD3,XPO6,POLR2A,USP15 |
| 4.875e-03 | -5.32 | CELL_CYCLE_PHASE | MSigDB lists | CELL_CYCLE_PHASE | 169 | 34 | 17758 | 2279 |
DCTN3,TTN,CUL4A,TAF1,KHDRBS1,DBF4,MAD2L2,ABL1,NEK6,TRIAP1,XRCC2,ANAPC11,ANAPC10,PDS5B,TIMELESS,RAN,MSH4,PRMT5,CDK6,KRT7,CDK4,FOXN3,POLA1,KIF15,TOP3A,TBRG4,RAD54B,CDC16,CUL2,PAM,RAD51B,ATM,NOLC1,ANAPC4 |
| 4.877e-03 | -5.32 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN | 194 | 38 | 17758 | 2279 |
SLC12A7,UNC13D,WDR75,PTCD2,SCAMP3,H2AFJ,MYH9,PABPC4,FLNB,FRRS1,CAD,ANAPC11,ALDH18A1,PLEKHA2,LPCAT1,RPL22L1,PPA1,TRIM14,SEC24A,APEX1,CRIM1,ELP3,MRRF,ODC1,EIF5B,SLC26A11,WARS,HLA-DMA,RARS,ZDHHC11,IKZF4,NSF,ATM,UMPS,BMP4,GALNT10,SETD6,RNF114 |
| 4.877e-03 | -5.32 | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | 194 | 38 | 17758 | 2279 |
LUZP1,TRIM16,URB2,LETMD1,NFX1,FOSL2,CLINT1,DENND3,ABL1,RABGAP1L,GTF2H1,HARS2,TTC3,CLDND1,ZMYM2,TOMM34,MICAL3,FAM98A,CHD9,PXN,RAP1B,SUMO3,RSBN1,CAMSAP2,TRIM37,ODC1,MAT2A,OXSR1,PES1,APBB3,ARL4A,SNAP23,ACP1,NCBP2,ABCC3,ITGB4,IQSEC2,PDLIM5 |
| 4.877e-03 | -5.32 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | 194 | 38 | 17758 | 2279 |
SCAMP3,SEC24D,CSNK2A1,BCOR,MLH1,SPATS2L,CCDC47,SLC25A44,REEP5,NDUFB3,COPS4,TANK,PPCDC,CLDND1,LARP4B,AHCYL1,HSD17B12,PTPRK,MTHFD1,TIMM8B,KLHL23,ITPA,ATOX1,WDR18,PSMA1,SLC35F2,TARS,MGAT2,YIF1A,HPRT1,KPNA3,WDR5B,NME7,TP53BP1,FDPS,SLC16A1,NFKBIB,ZBTB24 |
| 4.884e-03 | -5.32 | endodeoxyribonuclease activity | molecular function | GO:0004520 | 51 | 14 | 16491 | 2164 |
EXO1,HMGA2,RBBP8,SLX4,APEX1,APLF,XRCC2,RAD51B,TATDN3,FAN1,ALKBH1,TATDN1,OGG1,ZRANB3 |
| 4.901e-03 | -5.32 | cytoplasmic stress granule | cellular component | GO:0010494 | 32 | 10 | 17570 | 2233 |
DDX3X,LSM14A,ATXN2,PQBP1,EIF2S1,IGF2BP1,LARP4B,MBNL1,PABPC1,PABPC4 |
| 4.901e-03 | -5.32 | small-subunit processome | cellular component | GO:0032040 | 32 | 10 | 17570 | 2233 |
WDR36,MPHOSPH10,UTP14A,UTP15,NOL6,HEATR1,FBL,PDCD11,NOP58,NOP56 |
| 4.902e-03 | -5.32 | regulation of DNA repair | biological process | GO:0006282 | 73 | 18 | 16441 | 2138 |
HMGA2,CUL4A,APEX1,SIRT6,NPAS2,EYA3,BRCA1,UBR5,KDM1A,TERF2IP,BRE,TMEM161A,CDK9,H2AFX,BRCC3,OGG1,SPIDR,TERF2 |
| 4.909e-03 | -5.32 | CALM1 (calmodulin 1 (phosphorylase kinase, delta)) | protein interactions | 801 | 276 | 55 | 16036 | 2270 |
HERC2,VIPR1,MYCBP2,TTN,PCNT,STX8,EIF3C,ATRX,CAMK1,PTPRA,TCF3,MYO7A,RCHY1,CSNK2A1,PDCD7,CLINT1,UBR5,IQGAP2,DST,UBE3A,UCHL5,MYC,PPIL2,JOSD1,RDX,RNF2,KDM5C,CASP8AP2,LYST,TRIM13,CAMKK2,STAG1,KCNQ3,MYO10,RYR2,OBSCN,C11orf65,SYT1,FKBP3,PUM3,UBC,SNCA,DDX3X,RANBP2,SET,PAM,H2AFX,SVIL,USP20,BMI1,XRCC4,SRP14,KIF1B,MAPT,ZBTB24 |
| 4.915e-03 | -5.32 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | 430 | 74 | 17758 | 2279 |
CDCP1,CYLD,LUZP1,RBFOX2,OSBPL9,MFGE8,SPATS2L,TUBB6,DST,PRKD3,JAG1,S100A10,MMP14,ETF1,CMPK1,MET,CDK6,PERP,DSC3,PHLDB2,SKAP2,SSFA2,UPP1,WLS,PTPRM,ANKRD33B,VSNL1,CAV1,COTL1,NUDT15,DCBLD2,GNAI1,SMAD3,HOXA3,ANXA2,TNFRSF10D,NRP1,HMGA2,IGF2BP2,TRIM22,TGFBR2,INPP1,MBNL1,IGF2BP3,NAMPT,PTPN2,FKBP1A,GART,PTRF,DSG2,CD44,FMNL2,CAV2,NT5E,FDFT1,ARNTL2,LAMC1,PSAT1,FGF2,NXN,MBNL2,EHBP1,ANXA1,RETSAT,KPNA1,FSCN1,FGFBP1,HIF1A,TBPL1,RIOK3,SLC16A1,SVIL,KIF1B,HRH1 |
| 4.929e-03 | -5.31 | JmjN | interpro domains | IPR003349 | 10 | 5 | 18293 | 2341 |
KDM5C,KDM5B,KDM4B,KDM5A,KDM4C |
| 4.966e-03 | -5.31 | PFDN1 (prefoldin subunit 1) | protein interactions | 5201 | 83 | 21 | 16036 | 2270 |
FBXW4,TUBA1A,EIF3C,HARS,EIF4A2,TSN,SUMO3,CEP126,RMI1,NR2F1,SH3GL1,SEC31A,P3H1,TTC38,IFT140,PRPF4,PUS1,PFDN2,IGBP1,PRPS1,PRKACB |
| 4.967e-03 | -5.30 | GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN | MSigDB lists | GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN | 163 | 33 | 17758 | 2279 |
DNAJA4,MCM10,RSL1D1,PPIL1,TIMM10,RMI1,DENR,NOP56,SFR1,RPP30,MPHOSPH10,SLC7A11,TAF3,DHX33,PPCDC,DTNBP1,FXN,CDC37,TMPO,ARHGAP17,KIAA1143,GINS3,TEX19,MYO10,PSMC3IP,CYB5B,GEMIN5,INF2,TOE1,SAMD5,DNAH2,NOLC1,BAG1 |
| 4.971e-03 | -5.30 | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MSigDB lists | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 464 | 79 | 17758 | 2279 |
CYP24A1,RIBC2,ST3GAL6,HSPA1A,DST,ASNS,BCAS2,ARMC6,GSTA4,CORO1A,PRMT3,LYST,MPP6,CDK4,MARCKSL1,SOX4,MCM2,ENC1,DSP,CXADR,PLIN2,VDR,TCF7L1,AHNAK,KLF4,COPS5,PPP3CC,MAGI1,MTCH1,MEF2C,SARS,GTF2IRD1,BHLHE40,PHGDH,MAN1A1,FKBP1A,UBE3A,CTNNBL1,SUV39H2,MCM5,DSG2,NISCH,PPIL2,BUD31,TNPO3,TIMELESS,SHMT2,CD44,PRF1,POLR1E,SOX6,MTHFD1,KLRD1,SLC40A1,PRIM2,CRIM1,HOMER2,RHOT2,EVI5,KLF6,CYB5B,CHCHD6,MMAA,DDX49,TARS,HSPA1B,ANXA1,BICD1,TASP1,DAGLB,GTF2A1,SYNCRIP,PMEPA1,IFITM2,KIF1B,TESC,GPATCH4,IPO4,HRH1 |
| 4.972e-03 | -5.30 | MIZUSHIMA_AUTOPHAGOSOME_FORMATION | MSigDB lists | MIZUSHIMA_AUTOPHAGOSOME_FORMATION | 18 | 7 | 17758 | 2279 |
ATG12,ATG9A,RB1CC1,ZFYVE1,ATG3,AMBRA1,ATG7 |
| 4.975e-03 | -5.30 | MODULE_358 | MSigDB lists | MODULE_358 | 74 | 18 | 17758 | 2279 |
WDR75,MIOS,DBF4,TRAK1,MARCH6,SEC16A,DDX49,STK10,C1orf159,INSIG1,PMAIP1,INTS7,FMNL1,AEN,NOC3L,NMD3,STK4,LPP |
| 4.975e-03 | -5.30 | ORGANELLE_INNER_MEMBRANE | MSigDB lists | ORGANELLE_INNER_MEMBRANE | 74 | 18 | 17758 | 2279 |
TIMM8B,BCS1L,OPA1,TIMM10,NDUFS7,ATP5D,TAMM41,NDUFV1,ATP5G2,LEMD3,TIMM17A,MPV17,SURF1,PMPCA,SLC25A11,NDUFA6,SLC25A1,TIMM50 |
| 5.002e-03 | -5.30 | SHEPARD_CRUSH_AND_BURN_MUTANT_UP | MSigDB lists | SHEPARD_CRUSH_AND_BURN_MUTANT_UP | 188 | 37 | 17758 | 2279 |
SLC12A7,CYP24A1,EGR1,FN1,DDX19A,OLA1,ID2,RCAN1,NLE1,FOXO3,PHLDA2,SRPRB,HARS2,ETF1,SERPINH1,FBL,FTSJ3,POLR1E,HTRA2,SLC3A2,ABCF2,NOL8,NOL6,WBSCR22,MARS,ODC1,DDX49,PWP1,PES1,ZNF622,TSR1,MYBBP1A,ZNF330,DNAJA3,TIMM17A,FTSJ1,PTRH2 |
| 5.002e-03 | -5.30 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_DN | 188 | 37 | 17758 | 2279 |
SEPHS2,SRM,TNFRSF21,LAMTOR3,LPCAT3,CMTM3,SH2B3,ARHGAP18,SREBF2,SOCS1,SLC7A11,NOP16,BANF1,LTN1,SELT,LPCAT1,WDFY3,PPP1R21,HSPA5,MINA,MARCH6,SOX4,C19orf70,CRYBG3,MAT2A,ANXA1,MGAT2,GNG2,LSS,HPRT1,ARHGAP21,GADD45A,FDPS,ATG7,SVIL,ADAM9,DHCR7 |
| 5.031e-03 | -5.29 | LYPD3 (LY6/PLAUR domain containing 3) | protein interactions | 27076 | 99 | 24 | 16036 | 2270 |
DNM3,TBRG4,ARFIP2,DCUN1D5,XPO7,GDPD5,FLVCR1,SYMPK,GBF1,BZW2,SLC30A7,COMMD9,THADA,TMEM94,ORC5,PDS5B,TNPO3,C16orf58,RBM26,CLDND1,GALNT10,NR2F2,C2CD5,XPO6 |
| 5.032e-03 | -5.29 | GCM_GSTA4 | MSigDB lists | GCM_GSTA4 | 63 | 16 | 17758 | 2279 |
FAM172A,TSPYL4,RBFOX2,ATAT1,FOXO3,POGZ,RERE,APBB3,TMEM237,KIDINS220,ASTN2,CLEC16A,DCTN4,NISCH,GSTA4,PKNOX1 |
| 5.032e-03 | -5.29 | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN | 63 | 16 | 17758 | 2279 |
IFRD1,FGF2,UPP1,PRKCA,RPS6KA5,FGFR1,RAD54B,MYC,ATM,NT5C,GSTA4,MAP3K14,MET,OGG1,DDIT3,TOP1 |
| 5.036e-03 | -5.29 | MORF_RBBP8 | MSigDB lists | MORF_RBBP8 | 207 | 40 | 17758 | 2279 |
ATRX,PAFAH1B1,FAM189B,SLC2A1,KLHL18,TTI1,PSMF1,IQGAP2,RAP1A,TBC1D22A,MYC,NCKIPSD,CEP135,ZNF710,RPS6KB2,KAT8,PMS1,GTF2H3,CHD9,SIK3,MSX1,LSM12,SFSWAP,BMS1,EIF5B,PIK3CB,RERE,MFN2,HTR7,TAF2,RANBP2,SLC30A3,RBBP8,CHD3,CRCP,SLC25A11,NFRKB,RUNX1,ARC,ZBTB11 |
| 5.056e-03 | -5.29 | transcription factor TFTC complex | cellular component | GO:0033276 | 14 | 6 | 17570 | 2233 |
TAF2,TADA3,TAF12,TRRAP,TAF4,TAF9B |
| 5.062e-03 | -5.29 | response to starvation | biological process | GO:0042594 | 149 | 31 | 16441 | 2138 |
ACADS,FADS1,ATF4,FOXO1,MIOS,PPARG,UPP1,HSPA5,PDK4,SLC2A1,PIK3R4,ATG12,ADSL,ATG2B,GAS6,SIRT2,CAV1,TCF7L2,WNT2B,NPRL2,MYBBP1A,ASNS,SREBF2,PMAIP1,ATG7,RRAGA,BCAS3,EIF2S1,DDIT3,SEH1L,TNRC6A |
| 5.074e-03 | -5.28 | MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS | 47 | 13 | 17758 | 2279 |
TAMM41,PMAIP1,TIMM17A,MPV17,FIS1,NDUFS5,OPA1,TOMM34,NDUFS7,SLC25A1,TIMM50,TIMM44,MFN2 |
| 5.083e-03 | -5.28 | 4 iron, 4 sulfur cluster binding | molecular function | GO:0051539 | 41 | 12 | 16491 | 2164 |
NUBPL,ETFDH,NDUFV1,IREB2,PRIM2,PPAT,POLA1,TYW1,CDKAL1,LIAS,MUTYH,NDUFS7 |
| 5.119e-03 | -5.27 | BAG3 (BCL2-associated athanogene 3) | protein interactions | 9531 | 416 | 78 | 16036 | 2270 |
AAMDC,URB2,UROD,OLA1,C1QTNF7,SSBP2,NT5C3A,HSPA1A,PAIP2,ACD,COPS4,ATG3,DNAJB6,UBAP2L,GSTA4,ZNF3,TNK2,ZCCHC14,EVL,RAB7A,ARRDC3,PSMG1,MCL1,VIM,PYCR1,SMAD3,SLC7A1,RANBP2,TOM1L2,G6PD,ATG7,HSPB8,XPNPEP1,ANXA2,FAM118A,ANKS1A,PPIL3,BAG1,SSH2,MCM6,AK2,CLK1,TIMM10,ANXA10,PTPN2,FKBP1A,CNST,PTRF,TMSB10,MCM5,PVRL3,TRIAP1,ANXA5,S100A14,IGF2BP1,GMDS,CCDC88C,AMOT,PABPC1,RTFDC1,TERF2,PSAT1,TSTA3,WDFY3,EIF4A2,MRPS10,UBE2K,ZNF655,ISG15,ANXA1,NAP1L5,IRAK2,PSAP,MACROD1,NFKBIB,PDE9A,GALE,NR2C2AP |
| 5.125e-03 | -5.27 | GSE27786_LIN_NEG_VS_BCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_BCELL_DN | 182 | 36 | 17758 | 2279 |
ESCO1,ADAMTS6,ZFP36L1,CCDC47,RLF,UBL5,MGA,CEP164,RABGAP1L,ANKRD11,CPSF3,CCDC88C,LYPLA2,LYST,SNX29,USE1,PFKFB4,FAM120B,ANTXR2,TUBA1A,PPP1R21,SETD2,ZMYM5,KRTCAP2,SAP30BP,ARMC3,DHX57,SPOP,FBXL5,PAF1,BAZ2B,SUFU,SSU72,CHD3,CDK9,FIS1 |
| 5.125e-03 | -5.27 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | 182 | 36 | 17758 | 2279 |
SEC24D,HECTD3,SLC25A21,ARFIP2,SF3A3,SIRT2,RAC3,FLNB,NOP56,NPRL2,PDZD2,TRIAP1,IKBKB,PAK1IP1,YARS,ARHGAP17,PARP2,ZMYM5,C11orf80,TOP3A,SNAP25,EXOG,DHX57,IFT81,TCF7L1,SRCAP,ATAD5,CDC16,YIPF2,COPS5,FTSJ1,CDKAL1,NCBP2,CCNB1IP1,COPS6,MTCH1 |
| 5.125e-03 | -5.27 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_UP | 182 | 36 | 17758 | 2279 |
NDUFA5,URB2,HSD17B10,PIK3R4,TUBB6,POP5,IKBKAP,MRPS11,EDC3,FLAD1,GATC,SUV39H2,YLPM1,GPATCH1,POLR3B,POLE3,PRADC1,MCEE,FAM98A,DDX28,NFIA,NAPEPLD,USP46,PEX1,POP1,NAP1L5,FBXO21,COQ9,TSSC1,ARHGAP12,UMPS,RUNX1,COPS6,BLMH,SETD6,HRH1 |
| 5.127e-03 | -5.27 | TMTCGCGANR_UNKNOWN | MSigDB lists | TMTCGCGANR_UNKNOWN | 151 | 31 | 17758 | 2279 |
BANP,PIGN,LRRC28,ZNF414,TMEM183A,IDH3G,SMG7,ZNF346,SUPT5H,SSR4,DENR,DDX3X,TSR1,CAMK2D,TMCO1,ADNP,HNRNPH3,COQ9,CYB5D1,WDR73,RRAGA,BCAS3,PTPN4,SLC25A11,RBM26,RBPJ,POLR1C,AGL,LRSAM1,CDK12,ANAPC4 |
| 5.134e-03 | -5.27 | INTRACELLULAR_TRANSPORT | MSigDB lists | INTRACELLULAR_TRANSPORT | 278 | 51 | 17758 | 2279 |
SCAMP3,TRIP6,NF1,KIF5A,KHDRBS1,TRAK1,VPS45,VTI1A,MAP1S,MYH9,SMG7,MON2,XPO7,OPA1,NUP160,GBF1,RPAIN,EEA1,DOPEY1,PEX7,NUP133,NCKIPSD,UPF2,TOMM34,LYST,SLC25A1,CDC37,USE1,ATXN1,RHOT2,NUP214,NOP58,RERE,MFN2,TIMM44,PEX1,TAMM41,SMAD3,RANBP2,MYBBP1A,KPNA1,KPNA3,SNAP23,TIMM17A,STX18,NCBP2,PEX13,NAPA,KIF1B,XPO6,SMG1 |
| 5.135e-03 | -5.27 | UBAP2L (ubiquitin associated protein 2 like) | protein interactions | 9898 | 43 | 13 | 16036 | 2270 |
PMS1,UBAP2,FN1,COPS5,SIRT7,MED15,ATXN1,FUS,MLH1,BMI1,YEATS2,ISG15,NEDD4 |
| 5.135e-03 | -5.27 | HEXIM1 (hexamethylene bis-acetamide inducible 1) | protein interactions | 10614 | 43 | 13 | 16036 | 2270 |
DYNC1H1,BRD4,SURF2,HIF1A,CCNT1,CDK9,C10orf2,AP1M1,CSNK2A1,SHMT2,COPS7B,TERF2,OSBPL1A |
| 5.135e-03 | -5.27 | ASCC2 (activating signal cointegrator 1 complex subunit 2) | protein interactions | 84164 | 43 | 13 | 16036 | 2270 |
DEAF1,ASCC3,SNW1,ASCC1,GADD45A,ALKBH3,GNL3,OLA1,MYH9,RADIL,CUTC,KDM1A,RPA1 |
| 5.136e-03 | -5.27 | HMGA1 (high mobility group AT-hook 1) | protein interactions | 3159 | 78 | 20 | 16036 | 2270 |
NCOR2,CUL7,APEX1,FN1,PPARG,OLA1,POU2F1,CSNK2A1,PRKCA,HSPA1A,ANXA1,EIF2S2,SUFU,SYNCRIP,CWC27,HIPK2,BANF1,UPF2,ANXA2,TERF2 |
| 5.140e-03 | -5.27 | RNA polymerase II transcription factor complex | cellular component | GO:0090575 | 98 | 22 | 17570 | 2233 |
TCF12,GTF2H3,ATF4,PPARG,TAF1,TCF3,MED18,TAF9B,VDR,TAF2,TADA3,TRRAP,GTF2A1,HIF1A,TAF3,HIPK2,TAF4,TBPL1,GTF2H1,TAF12,CARM1,DDIT3 |
| 5.148e-03 | -5.27 | vesicle docking | biological process | GO:0048278 | 57 | 15 | 16441 | 2138 |
VPS18,CEP83,NSF,STX1A,EXOC6B,UNC13A,EXOC4,SCFD2,NDRG4,VPS45,SNAP25,CAV2,RAB10,RABEPK,EXOC6 |
| 5.175e-03 | -5.26 | EFTUD2 (elongation factor Tu GTP binding domain containing 2) | protein interactions | 9343 | 132 | 30 | 16036 | 2270 |
SART1,SARS,CUL7,FN1,PRPF31,HARS,SIRT6,XPO5,RANGAP1,UBR4,RPA1,ARPC3,TTC1,RANBP2,SNW1,ZNF622,BCAS2,DUS3L,HNRNPR,EEFSEC,MYC,COPS5,GPN1,PRPF4,RNF2,BMI1,SRRM2,HNRNPM,TOP1,PRPF19 |
| 5.181e-03 | -5.26 | RIZKI_TUMOR_INVASIVENESS_3D_UP | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_3D_UP | 201 | 39 | 17758 | 2279 |
TNNC1,TCF12,HMGA2,BRAF,UBN1,HLTF,PRR4,SSBP2,INPP1,PIP4K2A,BMP6,SLC39A1,BCAS2,PMAIP1,VAPB,NUDC,PCSK6,SLC3A2,RREB1,TSTA3,LIMA1,TMEM126A,EPS15L1,MRPS10,MARS,SEMA3F,PTK2,PIK3CB,FGFR1,MLLT10,GNAI1,SLC23A2,STOML2,TIMM17A,FTSJ1,PAM,RPS6KB1,ZNF32,MAP2K4 |
| 5.206e-03 | -5.26 | UBA1 (ubiquitin-like modifier activating enzyme 1) | protein interactions | 7317 | 121 | 28 | 16036 | 2270 |
GARS,CUL7,TXLNG,HSD17B10,SEMA3F,AP1B1,UBE2K,UBTD2,AARS,BIRC2,UBC,ISG15,CIAPIN1,UBE2E1,EPRS,ASNS,ARMC6,ATIC,COPS5,WDR73,AP1M1,XPNPEP1,ARHGAP1,FUS,NMD3,PABPC1,TRIP13,MTHFD1 |
| 5.218e-03 | -5.26 | RNA Polymerase III Transcription Initiation | REACTOME pathways | R-HSA-76046 | 35 | 11 | 8202 | 1117 |
POLR3D,POLR3E,POU2F1,CRCP,GTF3C3,POLR3B,POLR1C,SNAPC4,POLR3A,SNAPC5,POLR3G |
| 5.235e-03 | -5.25 | human chr6p21.1 | chromosome location | human chr6p21.1 | 74 | 15 | 26250 | 2590 |
CUL7,TNFRSF21,KLC4,XPO5,AARS2,ADCY10P1,MRPS10,PPIL1,YIPF3,MED20,SLC29A1,POLR1C,C6orf223,FOXP4-AS1,TJAP1 |
| 5.236e-03 | -5.25 | Anticodon-bd | interpro domains | IPR004154 | 14 | 6 | 18293 | 2341 |
HARS2,EPRS,GARS,POLG2,HARS,TARS |
| 5.242e-03 | -5.25 | MORF_MSH3 | MSigDB lists | MORF_MSH3 | 233 | 44 | 17758 | 2279 |
TNIK,SPRED2,EP400,NF1,ATRX,SLC2A1,NFX1,KLHL18,BARX2,MON2,TTI1,RPS6KA5,CDC73,PSMF1,RAP1A,SURF2,TBC1D22A,SYNJ2,AMOT,CASP10,CHD9,TTLL5,PRIM2,RREB1,POLA1,KIAA0586,SULT4A1,BRCA1,PIK3CB,USP46,ERC1,MLLT10,HTR7,TAF2,CACNB1,ZNF266,MSH3,HIC2,USP20,FNTB,PPP1R12B,ARHGAP12,RUNX1,SMG1 |
| 5.245e-03 | -5.25 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN | 176 | 35 | 17758 | 2279 |
SEPHS2,C16orf52,SMG7,SPATS2L,RMI1,YARS2,NOP56,SCN1B,PAK1IP1,WIZ,ERRFI1,CNOT4,MTHFD2L,CLK2,MARCH9,ZNF234,KLHL23,ELP3,C1QTNF1,XPO5,PSMA1,APTX,RBM28,SYT1,EIF5B,LSG1,USP36,ELP2,KPNA3,WDR5B,SERINC1,CC2D1B,FAM114A2,RRAGA,POLR1C |
| 5.247e-03 | -5.25 | extragonadal | COSMIC cancer mutations | extragonadal | 170 | 34 | 17775 | 2278 |
BRAF,NF1,TNFRSF21,WDR26,NLE1,DNAH1,RPGRIP1L,SMARCB1,KDM2A,INTS7,SEMA3D,PRICKLE2,KMT2A,YARS,SRPK2,SPTAN1,RPS6KB2,FLNC,LAMA4,NRAS,TTLL5,ADAMTSL3,JMJD1C,TOP3A,SON,PHF6,ATP9B,SMAD3,EIF4ENIF1,BAZ2B,HLCS,SOCS4,ATM,RUNX1 |
| 5.253e-03 | -5.25 | MILI_PSEUDOPODIA | MSigDB lists | MILI_PSEUDOPODIA | 42 | 12 | 17758 | 2279 |
PHLDB2,ZBTB12,CENPB,ANKRD11,DDR2,EIF2A,DKC1,PALLD,BMI1,INPP1,SAMD4A,DCAF5 |
| 5.259e-03 | -5.25 | SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY | MSigDB lists | SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY | 32 | 10 | 17758 | 2279 |
SRM,FARSA,DDX28,SCAMP3,ARMC6,CCDC85B,SMG7,ARFIP2,NDUFS5,PYCR1 |
| 5.259e-03 | -5.25 | HU_GENOTOXIC_DAMAGE_24HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_24HR | 32 | 10 | 17758 | 2279 |
NAA38,MTHFD2,ATF4,PSAT1,BANF1,H2AFX,ALDH18A1,HERPUD1,ISG15,BATF3 |
| 5.259e-03 | -5.25 | CAFFAREL_RESPONSE_TO_THC_UP | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_UP | 32 | 10 | 17758 | 2279 |
SEC31A,SLC3A2,ASNS,SERINC1,MYC,SHMT2,ZFP36L1,ZRANB2,UBR4,HERPUD1 |
| 5.284e-03 | -5.24 | UBE2B (ubiquitin conjugating enzyme E2B) | protein interactions | 7320 | 73 | 19 | 16036 | 2270 |
SEC24A,UBR5,UBR4,BIRC2,UBC,TTC1,RNF40,SRSF2,RAD18,UBR1,WAC,ZRANB2,SSBP1,SERPINH1,AHCYL1,IGBP1,ZMYM2,CNOT4,NIPSNAP1 |
| 5.289e-03 | -5.24 | negative regulation of mRNA 3'-end processing | biological process | GO:0031441 | 10 | 5 | 16441 | 2138 |
RNF40,CTR9,SUPT5H,CCNT1,CDK9 |
| 5.289e-03 | -5.24 | protein deneddylation | biological process | GO:0000338 | 10 | 5 | 16441 | 2138 |
COPS7B,COPS6,COPS4,COPS3,COPS5 |
| 5.289e-03 | -5.24 | negative regulation of inclusion body assembly | biological process | GO:0090084 | 10 | 5 | 16441 | 2138 |
SACS,DNAJA4,DNAJB6,HSPA1A,HSPA1B |
| 5.302e-03 | -5.24 | PPP1CA (protein phosphatase 1, catalytic subunit, alpha isozyme) | protein interactions | 5499 | 277 | 55 | 16036 | 2270 |
CHMP2A,CUL7,FN1,SUPT6H,SIRT7,ID2,GYG1,CEP126,TGFBR2,STAM,PPP1R9A,PCDH7,SMARCB1,TOX4,CAD,ZNF827,MPHOSPH10,CNST,ASNS,YLPM1,MYC,LPIN2,IKBKB,ZNF326,POLR3B,AKAP11,NOM1,PPP1R9B,DEAF1,GLTSCR2,CDK4,PREX1,RYR2,CAV1,BRCA1,PTK2,SON,PEAK1,POLR3A,POLR2A,VDR,TOE1,SYNCRIP,STX1A,ARNTL,POLR3E,TNFRSF1A,H2AFX,CCDC85B,CSRNP1,ATM,APAF1,NCOR1,ZBTB11,CEP170 |
| 5.311e-03 | -5.24 | MODULE_509 | MSigDB lists | MODULE_509 | 14 | 6 | 17758 | 2279 |
SQLE,IDI1,SEC24D,AP2S1,FDPS,FDFT1 |
| 5.311e-03 | -5.24 | CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY | MSigDB lists | CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY | 14 | 6 | 17758 | 2279 |
PDE2A,PDE4A,PDE3B,PDE10A,PDE3A,PDE4B |
| 5.316e-03 | -5.24 | JmjN | pfam domains | PF02375 | 10 | 5 | 16629 | 2165 |
KDM5C,KDM5B,KDM4B,KDM5A,KDM4C |
| 5.324e-03 | -5.24 | KDM1A (lysine (K)-specific demethylase 1A) | protein interactions | 23028 | 295 | 58 | 16036 | 2270 |
NOSTRIN,ZNF516,ESCO1,CCDC53,TCF3,SIRT7,ID2,CSNK2A1,IKBIP,PDCD5,GABPB2,PELP1,HSPA1A,KDM1A,SLC25A20,PHC2,TADA3,EXOC1,PEX7,KANSL1,UCHL5,MBD2,MYC,GLYR1,SOCS6,RNF2,CCDC121,ZMYM2,SAMD3,TIMM50,ELOF1,PRAME,VPS37A,PRIM2,RREB1,KDM5B,KRT7,SMARCAD1,ZNF480,HAUS6,PRDM1,BRCA1,LENG8,GSTCD,SERGEF,RPA1,DNTTIP1,SMARCC1,TP53BP1,L3MBTL3,CHD3,ZNF333,DNAJA3,ZNF436,ASB3,RBPJ,KLHDC4,ZBTB24 |
| 5.326e-03 | -5.24 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 195 | 38 | 17758 | 2279 |
SLC12A7,MYCBP2,SPRED2,XPC,DYM,SMAD7,SSBP2,PABPC4,NOP56,SKI,RNF141,GART,EIF2S2,ENTPD5,MYC,FBL,TOMM34,LONP1,METTL1,SLC3A2,EVL,PDK1,RREB1,APEX1,CDK4,GNL3,RABAC1,IL6R,ARID1A,KLF6,ODC1,RERE,TSR1,GADD45A,KLF4,D2HGDH,PAM,IPO4 |
| 5.326e-03 | -5.24 | SANSOM_APC_TARGETS_REQUIRE_MYC | MSigDB lists | SANSOM_APC_TARGETS_REQUIRE_MYC | 195 | 38 | 17758 | 2279 |
SRM,MVK,TTC27,POLR1A,HES6,VARS,PHGDH,PABPC4,NOP56,CAD,NRF1,MYC,TIMELESS,SHMT2,EXOSC4,FBL,OGG1,TMPO,METTL1,SIGMAR1,CDK4,ARHGEF12,SOX4,DDX49,TMEM186,CENPP,DUS3L,SRRD,HSPBAP1,D2HGDH,BIVM,SNX24,USP20,MDN1,GALNT10,TSEN2,METTL2B,MUTYH |
| 5.326e-03 | -5.24 | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | 195 | 38 | 17758 | 2279 |
SRM,DCTN3,SDSL,PRKCSH,DLGAP4,RTN4,TUBB6,HLTF,ANXA10,SLC25A20,NEK6,THAP4,SLC39A7,AP1M1,ANXA5,PXK,LPCAT1,PABPC1,PERP,CDC37,MYB,RAB7A,C1QTNF1,ODC1,STK10,ST3GAL5,ARIH2,PLIN2,SERF2,RPL28,SSU72,GADD45A,INTS5,NSMCE1,SCARB1,NDUFS5,PSAP,PKIB |
| 5.326e-03 | -5.24 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 195 | 38 | 17758 | 2279 |
KLHL24,MFGE8,TNXB,WDR26,CCNL2,TRIM22,BHLHE40,DDX60L,LPIN1,PLXNB1,MAN1A1,JAG1,IDI1,CLCN6,ERRFI1,ETV1,ZBTB17,FADS1,SLC40A1,EIF4E3,SESN2,KDM5B,ARID5B,ATP6V0A1,MEF2D,GLS,LSS,SERF2,INSIG1,ELP2,MBTD1,FDPS,BDH2,SQLE,SVIL,ARHGAP12,IGBP1,ZMAT3 |
| 5.326e-03 | -5.24 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_UP | 195 | 38 | 17758 | 2279 |
SEPHS2,ARHGAP26,MCM10,SCAMP3,UTP14A,MRI1,PRAF2,ID2,VARS,GYG1,PABPC4,SHC1,DSG2,MSH4,GEMIN4,CD44,MET,SLC25A23,LPCAT1,LYST,DDX28,TFPI,UTP15,LGALS1,ANXA1,RERE,GNAI1,SMAD3,AHNAK,HIF1A,DNAJA3,GPN1,PUS1,ANXA2,TXN2,ADK,TESC,RBP1 |
| 5.326e-03 | -5.24 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP | 195 | 38 | 17758 | 2279 |
ASCC1,ARID2,ITFG1,UROD,MLH1,HLTF,PIP4K2A,AMPD3,NAV1,SLC39A7,ANAPC11,GLTP,CPSF3,PXK,PRKACB,IPO11,DDHD1,RFC3,CDK4,MTIF2,RAP1GDS1,FKBP3,STK10,NCDN,VAC14,ECH1,KIF16B,TMCO1,DAGLB,FAM114A2,COQ9,KLF4,HERC1,HK2,EXOC4,RNF138,H2AFX,CNDP2 |
| 5.332e-03 | -5.23 | GENTILE_UV_RESPONSE_CLUSTER_D5 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D5 | 37 | 11 | 17758 | 2279 |
UBTF,MLX,ZHX3,FERMT2,JMJD6,PITPNB,DLX2,FOSL2,STAM,DDIT3,NAV3 |
| 5.354e-03 | -5.23 | HNRNPD (heterogeneous nuclear ribonucleoprotein D) | protein interactions | 3184 | 189 | 40 | 16036 | 2270 |
IMMP2L,CUL7,CUL4A,FN1,PCSK7,IGF2BP2,SNAPC4,HNRNPA3,DENR,ERI1,MYC,BANF1,RMDN3,GTF3C3,EXOSC4,SLC27A5,TOMM34,PABPC1,IPO11,SLC3A2,PTBP2,SMARCAD1,LDHA,SHISA5,BRCA1,TARS,PYCR1,RPA1,AHNAK,SYNCRIP,HNRNPR,HNRNPH3,COPS5,CDK9,CUL2,H2AFX,GPN1,ADGRE5,FUS,COPS6 |
| 5.355e-03 | -5.23 | mitochondrial respiratory chain complex I biogenesis | biological process | GO:0097031 | 18 | 7 | 16441 | 2138 |
NUBPL,NDUFAF5,NDUFS5,COA1,FOXRED1,NDUFS7,BCS1L |
| 5.355e-03 | -5.23 | NADH dehydrogenase complex assembly | biological process | GO:0010257 | 18 | 7 | 16441 | 2138 |
NUBPL,NDUFAF5,NDUFS5,COA1,FOXRED1,NDUFS7,BCS1L |
| 5.355e-03 | -5.23 | transcription elongation from RNA polymerase III promoter | biological process | GO:0006385 | 18 | 7 | 16441 | 2138 |
CRCP,POLR3D,POLR3B,POLR1C,POLR3A,POLR3E,POLR3G |
| 5.355e-03 | -5.23 | mitochondrial respiratory chain complex I assembly | biological process | GO:0032981 | 18 | 7 | 16441 | 2138 |
NUBPL,NDUFAF5,NDUFS5,COA1,FOXRED1,NDUFS7,BCS1L |
| 5.355e-03 | -5.23 | termination of RNA polymerase III transcription | biological process | GO:0006386 | 18 | 7 | 16441 | 2138 |
CRCP,POLR3D,POLR3B,POLR1C,POLR3A,POLR3E,POLR3G |
| 5.361e-03 | -5.23 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | 170 | 34 | 17758 | 2279 |
PTP4A1,VIPR1,DCTN3,RBM33,ITPRIP,FOSL2,PRKCA,FAM8A1,DDIT4,SUCLG2,FHIT,CHD9,IL11RA,TSPYL4,AGPAT4,PTPRM,RAP1GAP2,ARRDC3,MEF2D,ENC1,SOX4,MBNL2,TTC28,ST3GAL5,SKIL,ZDHHC11,GADD45A,AGTPBP1,KLF4,ABHD3,PPP3CC,PDE9A,SMYD3,LPP |
| 5.363e-03 | -5.23 | Primary tooth development (number of teeth)(PMID:20195514) | GWAS genes | Primary tooth development (number of teeth)(PMID:20195514) | 3 | 3 | 2389 | 419 |
MSRB3,IGF2BP1,RAD51B |
| 5.363e-03 | -5.23 | Hippocampal volume(PMID:22504421) | GWAS genes | Hippocampal volume(PMID:22504421) | 3 | 3 | 2389 | 419 |
DPP4,MSRB3,ASTN2 |
| 5.363e-03 | -5.23 | eye | COSMIC cancer mutations | eye | 624 | 102 | 17775 | 2278 |
CGN,AMOTL1,ABCA3,PCNT,ARID2,NF1,OSBPL9,NTSR1,TRPM6,MKS1,BCOR,PTPRG,SYNJ1,UBR5,GBF1,EDC3,SMARCB1,EXOC1,ZNHIT6,INTS12,GSTA4,RNF2,MET,HRG,KMT2A,KIAA1549,DENND1A,MPST,KDM3B,SLC38A6,TNK2,EVL,SESN2,NRAS,KRT7,MIOS,VWCE,PREX1,ATG12,MCL1,KCNH3,BRCA1,KMT2C,TTC28,FLVCR1,MAK16,FGFR1,PDE8B,DCBLD2,STOML2,UBTF,BRCA2,SUFU,ITGA2,CTAGE5,VPS13D,RUNX1,ANXA2,WDR66,PPIL3,SMG1,USP15,TNRC6A,XYLB,BRAF,PRAF2,PDE4B,MLH1,LIAS,ABL1,IL17RE,ABCA5,SEC24C,SEMA3D,NLGN3,PABPC1,HSD17B14,DDHD1,VOPP1,RANBP6,TRAPPC9,ZFYVE1,KCNMA1,OBSCN,MEN1,GPNMB,EXOG,ANXA1,CENPP,RETSAT,MYBBP1A,SPAG9,PALB2,HERC1,SDCCAG8,ATM,MYOM2,MTMR1,NUDT22,MAP2K4,ANAPC4,COG5 |
| 5.384e-03 | -5.22 | HPRT1 (hypoxanthine phosphoribosyltransferase 1) | protein interactions | 3251 | 25 | 9 | 16036 | 2270 |
HPRT1,CUL7,NME1-NME2,PSAT1,PPID,PPAT,APRT,FUS,SNCA |
| 5.384e-03 | -5.22 | USB1 (U6 snRNA biogenesis 1) | protein interactions | 79650 | 25 | 9 | 16036 | 2270 |
SNW1,BCAS2,PLRG1,BUD31,CSNK2A1,GPATCH1,CWF19L2,DHX35,PRPF19 |
| 5.384e-03 | -5.22 | TIMM9 (translocase of inner mitochondrial membrane 9 homolog (yeast)) | protein interactions | 26520 | 25 | 9 | 16036 | 2270 |
TIMM8B,SART1,NDUFV1,PRDX6,TIMM10,HNRNPM,MPST,HTRA2,NUDC |
| 5.384e-03 | -5.22 | NUP43 (nucleoporin 43kDa) | protein interactions | 348995 | 25 | 9 | 16036 | 2270 |
CUL7,CUL4A,NUP133,KLC4,LAGE3,NUP160,SEH1L,ISG15,UBC |
| 5.384e-03 | -5.22 | LAS1L (LAS1-like, ribosome biogenesis factor) | protein interactions | 81887 | 25 | 9 | 16036 | 2270 |
CUL7,SMARCAD1,SIRT7,WDR18,SENP3,RNF2,BMI1,PELP1,UBC |
| 5.384e-03 | -5.22 | DDX52 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 52) | protein interactions | 11056 | 25 | 9 | 16036 | 2270 |
MPHOSPH10,NOL10,HLCS,COPS5,MYC,SIRT7,RSL1D1,RNF2,PUM3 |
| 5.393e-03 | -5.22 | - | gene3d domains | 1.10.1300.10 | 21 | 8 | 9988 | 1398 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 5.393e-03 | -5.22 | - | gene3d domains | 3.30.565.10 | 21 | 8 | 9988 | 1398 |
BCKDK,PMS1,SACS,PDK1,TRAP1,PDK4,MLH1,MORC2 |
| 5.403e-03 | -5.22 | MED12 (mediator complex subunit 12) | protein interactions | 9968 | 68 | 18 | 16036 | 2270 |
BRD4,MED27,SIRT7,MED13L,MED18,MED16,ZC3H13,VDR,TRRAP,EHMT2,HIF1A,MYC,CDK9,MED15,MED24,MED20,BMI1,LYST |
| 5.403e-03 | -5.22 | PFAS (phosphoribosylformylglycinamidine synthase) | protein interactions | 5198 | 68 | 18 | 16036 | 2270 |
PRDX6,GINS3,PPAT,SIRT7,FERMT2,RAP1GDS1,ADSL,BZW2,VAC14,WARS,FLAD1,GART,TTC38,UBR1,SHMT2,TNFRSF10D,VCL,PABPC1 |
| 5.403e-03 | -5.22 | BRCA2 (breast cancer 2, early onset) | protein interactions | 675 | 68 | 18 | 16036 | 2270 |
BCCIP,PMS1,FANCD2,BRCA1,NEDD4,RPA1,SMAD3,BRE,PALB2,DTNBP1,PDS5B,H2AFX,ATM,SERPINH1,USP11,BRCC3,UQCC1,EMSY |
| 5.403e-03 | -5.22 | XPO7 (exportin 7) | protein interactions | 23039 | 68 | 18 | 16036 | 2270 |
CARS,GARS,NARS,POLK,SIRT7,JMJD6,TTC1,COMMD9,GART,SEC24C,VPS37B,HIRIP3,RAN,USP11,TROVE2,PRMT3,CARM1,NT5E |
| 5.406e-03 | -5.22 | Biosynthesis of antibiotics | KEGG pathways | hsa01130 | 210 | 40 | 6908 | 881 |
SDSL,AK2,MVK,SUCLG1,AK6,HSD17B10,PHGDH,ADH5,AMPD3,GART,IDI1,ATIC,PYCRL,SUCLG2,SHMT2,PCK2,PRPS1,HMGCR,FDFT1,PSAT1,PPAT,PCCA,IDH3G,LDHA,ADSL,ODC1,DLST,PYCR1,PGD,CAT,LSS,NME1-NME2,NME7,G6PD,FDPS,HK2,FNTB,SQLE,BPNT1,GCSH |
| 5.421e-03 | -5.22 | CAGTATT,MIR-200B,MIR-200C,MIR-429 | MSigDB lists | CAGTATT,MIR-200B,MIR-200C,MIR-429 | 452 | 77 | 17758 | 2279 |
FEZ2,ATRX,ARID2,SYNJ1,GIT2,AMBRA1,PCDH7,SRSF2,DNAJB6,JAZF1,SLC38A2,PDS5B,ZEB1,BCAP29,PRKACB,CHD9,HMBOX1,GPM6A,AEBP2,RAB7A,NFIA,ATXN1,SEMA3F,DDX3X,KLF4,PAM,HIC2,CSMD3,RPS6KB1,BMI1,ZNF532,TMCC1,EFNB2,SSH2,FN1,KHDRBS1,ID2,RLF,FAM8A1,MTUS1,ASAP1,BUD31,ERRFI1,NRIP1,CNOT4,LYPLA2,MYB,NAV3,PPP1R9B,LAMC1,WDFY3,TEAD1,SMARCAD1,RDH10,RAP1B,FERMT2,MEX3B,PRDM1,SNAP25,R3HDM2,SYT1,EIF5B,EVI5,PHF6,SLC23A2,MGAT2,NAP1L5,LRP1B,BAZ2B,SERINC1,KIAA0355,STX1A,TAF4,EIF2S1,CNOT6,SH3PXD2A,HS2ST1 |
| 5.426e-03 | -5.22 | response to hyperoxia | biological process | GO:0055093 | 27 | 9 | 16441 | 2138 |
CAT,POLB,BDNF,FOXO1,EGR1,PPARG,CDK4,ATG7,CAV1 |
| 5.426e-03 | -5.22 | response to increased oxygen levels | biological process | GO:0036296 | 27 | 9 | 16441 | 2138 |
CAT,POLB,BDNF,FOXO1,EGR1,PPARG,CDK4,ATG7,CAV1 |
| 5.426e-03 | -5.22 | positive regulation of cell cycle G1/S phase transition | biological process | GO:1902808 | 27 | 9 | 16441 | 2138 |
DDX3X,CUL4A,ANKRD17,PLRG1,RDX,PPP1R1C,PLCB1,LSM10,ANXA1 |
| 5.433e-03 | -5.22 | PRMT1 (protein arginine methyltransferase 1) | protein interactions | 3276 | 138 | 31 | 16036 | 2270 |
CUL7,FN1,FGF2,WDFY3,GLTSCR2,KHDRBS1,ZMYM5,GRHL3,BRCA1,SUPT5H,SH3GL1,ARPC3,C20orf196,SYNCRIP,YLPM1,HNRNPR,MBD2,VPS72,CUL2,SHMT2,COPS7B,FUS,RUNX1,FBL,WDR33,NRIP1,CARM1,SAMD3,TERF2,CDC37,RPS6KB2 |
| 5.434e-03 | -5.22 | regulation of histone methylation | biological process | GO:0031060 | 52 | 14 | 16441 | 2138 |
PAF1,SNW1,NSD1,WDR61,PAXBP1,SUPT6H,CTR9,BCOR,BRCA1,SETD7,KMT2A,KDM1A,MYB,SMARCB1 |
| 5.434e-03 | -5.22 | intrinsic apoptotic signaling pathway by p53 class mediator | biological process | GO:0072332 | 52 | 14 | 16441 | 2138 |
SNW1,MYBBP1A,BRCA2,PMAIP1,HIPK2,TMEM109,CDIP1,AEN,SHISA5,FHIT,ZNF346,ZMAT3,PERP,DDIT4 |
| 5.444e-03 | -5.21 | NAD(P)-bd_dom | interpro domains | IPR016040 | 152 | 31 | 18293 | 2341 |
SUCLG1,TSTA3,KCNMA1,RDH10,HSD17B10,LDHA,MTHFD1L,PHGDH,AHCYL2,HSD3B7,PGD,PYCR1,RDH11,ADH5,DECR1,MTHFD2,HSDL2,DCXR,CBR4,G6PD,PYCRL,GLYR1,BDH2,ME1,GMDS,AHCYL1,MTHFD2L,HSD17B12,MTHFD1,HSD17B14,GALE |
| 5.455e-03 | -5.21 | EPAS1 (endothelial PAS domain protein 1) | protein interactions | 2034 | 105 | 25 | 16036 | 2270 |
ARNTL2,AKAP8L,DPF2,MED27,SMARCA4,MED18,MED16,IKBKAP,ARID1B,KDM1A,UBC,BATF3,SMARCB1,YTHDF2,TERF2IP,SMAD3,SMARCC1,HIF1A,MED15,ARNTL,MED24,GTF3C3,MED20,DDIT3,MEF2C |
| 5.467e-03 | -5.21 | DCUN1D1 (DCN1, defective in cullin neddylation 1, domain containing 1) | protein interactions | 54165 | 230 | 47 | 16036 | 2270 |
CUL4A,CEMIP,KLHL18,PLOD1,BTBD9,HSPA1A,HNRNPA3,PABPC4,NEDD4,DDX56,ASNS,COPS4,COPS3,CYB5D1,ZNF326,SOCS6,COPS7B,SSBP1,YBX3,AGL,PABPC1,MTHFD1,HMGCR,RNMT,KLHL23,LSM12,ARRDC3,HSPA5,DHX57,POLR2A,UBC,HSPA1B,DDX3X,KLHL22,TRRAP,SYNCRIP,HIF1A,HNRNPH3,COPS5,VPS37B,CUL2,ASB3,FUS,COPS6,XPO6,LRRC41,GALE |
| 5.467e-03 | -5.21 | RNA Polymerase III Abortive And Retractive Initiation | REACTOME pathways | R-HSA-749476 | 40 | 12 | 8202 | 1117 |
POLR3D,POLR3E,NFIA,POU2F1,CRCP,GTF3C3,POLR3B,POLR1C,SNAPC4,POLR3A,SNAPC5,POLR3G |
| 5.467e-03 | -5.21 | RNA Polymerase III Transcription | REACTOME pathways | R-HSA-74158 | 40 | 12 | 8202 | 1117 |
POLR3D,POLR3E,NFIA,POU2F1,CRCP,GTF3C3,POLR3B,POLR1C,SNAPC4,POLR3A,SNAPC5,POLR3G |
| 5.470e-03 | -5.21 | GSE30083_SP1_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_UP | 189 | 37 | 17758 | 2279 |
IFT57,AARS2,MEX3A,PLA2G12A,QSER1,TMEM132A,RBM19,UBTD2,NEDD4,FKBP1A,MCAM,SCN1B,ANP32B,TMEM120B,HSD17B12,PRPF19,TNK2,GPHN,LAMC1,TUBA1A,ZNF821,AGPAT4,MARCKSL1,NXN,RYR2,TCF7L2,TPK1,IFT81,LSS,SMARCC1,WDR35,NCBP2,KLHDC4,BLMH,CTXN1,HS2ST1,ATXN7L2 |
| 5.470e-03 | -5.21 | GSE3982_DC_VS_BASOPHIL_DN | MSigDB lists | GSE3982_DC_VS_BASOPHIL_DN | 189 | 37 | 17758 | 2279 |
PTP4A1,CYLD,KIF5A,DPF2,MED13L,NECAP1,RLF,DENND3,FAM8A1,GIT2,PCYOX1L,NAMPT,TERF2IP,CHN1,ZNF358,ZNF586,PMAIP1,ZEB1,INTS12,ZNF142,NLGN3,CEP63,MFAP2,SF3A1,MYB,TRA2A,KDM5A,HIST1H4J,R3HDM2,SPOP,PEX1,ZNF266,RIOK3,DPP4,IFITM2,SMYD3,DDIT3 |
| 5.470e-03 | -5.21 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 189 | 37 | 17758 | 2279 |
ITFG1,PLOD1,SPATS2,CLINT1,INPP1,RPAIN,BIRC2,STAM,CDC73,SLC39A7,HIBCH,CCDC88C,AVEN,SEC24A,PDK1,PARP2,C11orf80,ATXN1,PRDM1,PPIP5K2,SLC50A1,DDX49,ISG15,HERPUD1,SLC39A14,RARS,GADD45A,SERF2,DNAJC1,TTC38,NSF,ZCCHC6,PTRH2,XPNPEP1,RBPJ,EIF2B3,BLMH |
| 5.470e-03 | -5.21 | GSE17721_PAM3CSK4_VS_CPG_16H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_16H_BMDM_DN | 189 | 37 | 17758 | 2279 |
CARS,SARS,STX8,PLRG1,LETMD1,IGF2BP2,GRINA,CCNL2,SLC6A8,SH2B3,EIF2S2,COPS4,SNTG2,LPIN2,ANKRD24,DTNBP1,MET,NT5M,PLEKHA2,PXN,GARS,SHISA5,ZNFX1,APTX,SERP1,MRPL36,PES1,FSCN1,G6PD,SRD5A3,SYNGR2,TMEM219,DPEP1,ZNF397,PGAM5,CCNB1IP1,IGBP1 |
| 5.470e-03 | -5.21 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN | 189 | 37 | 17758 | 2279 |
SART1,ANKRD17,NDUFS7,NDUFV1,MPHOSPH10,SREBF2,COPS3,VPS52,SHMT2,CELF1,PCK2,CDK6,ATP6V0D1,PRKACB,ZNF629,RBCK1,SETD1B,SKAP2,TSTA3,ITPA,MTIF2,PCMT1,USP10,CHAF1A,MFN2,PWP1,TRRAP,HNRNPR,CFD,SET,WDR7,ACP1,MDN1,IQSEC2,AP2S1,HS2ST1,KAT6A |
| 5.470e-03 | -5.21 | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN | 189 | 37 | 17758 | 2279 |
XPC,WDR74,PDE4B,SMAD7,SBF2,NECAP1,FOXP1,SH2B3,RNF141,MPHOSPH10,RABGAP1L,CNOT4,PRMT3,TOMM34,HTRA2,LONP1,RABEPK,SLC3A2,EVL,DDX24,TFCP2,ZNF821,POU2F1,IL6R,MAT2A,RERE,MLLT10,GADD45A,ARID3B,KLF4,PER1,D2HGDH,SVIL,GALNT10,RPS6KC1,MUTYH,IPO4 |
| 5.471e-03 | -5.21 | UEDA_PERIFERAL_CLOCK | MSigDB lists | UEDA_PERIFERAL_CLOCK | 164 | 33 | 17758 | 2279 |
PTP4A1,PPDPF,AK2,MCM10,TRIP6,UBXN1,HES6,ID2,PLA2G12A,SLC29A1,BHLHE40,MAP2K3,FDX1,IDI1,S100A10,ATXN2,LPIN2,UBAP2L,C6orf89,HMGCR,TUBA1A,ELOVL6,GPCPD1,FERMT2,CYB5B,CPT1A,ST3GAL5,TARS,HERPUD1,FBXO21,FDPS,ARNTL,DHCR7 |
| 5.473e-03 | -5.21 | FAF2 (Fas associated factor family member 2) | protein interactions | 23197 | 172 | 37 | 16036 | 2270 |
DMXL2,INSIG2,ACTG1,NF1,WDR26,UBR5,MCM9,UBE3A,S100A10,INTS7,UBR1,VPS52,VAPB,RNF2,SERPINH1,MRPL21,LPCAT1,ARL14EP,AUP1,MTHFD1,HMGCR,GDAP1,TUBA1A,ATG9A,RAB7A,CAV1,MCM2,UBR4,UBC,VPS13C,KIDINS220,DAGLB,INSIG1,HIF1A,CUL2,SQLE,NOCT |
| 5.477e-03 | -5.21 | FEVR_CTNNB1_TARGETS_DN | MSigDB lists | FEVR_CTNNB1_TARGETS_DN | 534 | 89 | 17758 | 2279 |
TCF12,VMA21,POLB,TUBE1,BCOR,NOP56,SRSF2,BCAS2,ZFHX3,PPID,ZNHIT6,UCHL5,PDS5B,ZNF148,AHCYL1,TRIP13,CTC1,CASP8AP2,TMPO,RFC4,PMS1,RFC3,EVL,PPARG,PNN,BRCA1,SOX4,MCM2,FKBP3,EXO1,BRCA2,HNRNPR,EEFSEC,PQBP1,ACP1,SLC4A7,PRPF4,SCARB1,NOLC1,LPP,HMGA2,MCM6,TRIP6,SF3A3,RSF1,IKBKAP,PHGDH,GART,EIF2S2,MCM5,TIMELESS,GEMIN4,POLR1B,FBL,CD44,NRIP1,PABPC1,MYB,MTHFD1,MSI2,SLC40A1,APEX1,PRIM2,ALG6,PPAT,CRIM1,RB1CC1,POLA1,PSMC3IP,HAUS6,PSMA1,ADSL,EIF2A,IMPDH2,TRIM37,CPT1A,NOP58,RPA1,CENPP,ZFP62,POLE2,UBAP1,FGFBP1,SET,RNF138,MSH3,EIF2S1,IFITM2,ARHGAP27 |
| 5.483e-03 | -5.21 | MSH6 (mutS homolog 6) | protein interactions | 2956 | 63 | 17 | 16036 | 2270 |
PMS1,ANKRD17,POLK,SIRT6,SMARCAD1,SIRT7,CSNK2A1,BRCA1,MLH1,SUPT5H,CHAF1A,SLX4,MYC,MSH3,ATM,MUTYH,RPS6KB2 |
| 5.512e-03 | -5.20 | Notch-mediated HES/HEY network | Pathway Interaction DB | hes_heypathway | 48 | 14 | 2227 | 319 |
NCOR2,CAMK2D,RBBP8,ID1,GATA6,HIF1A,SPEN,TCF3,HES6,RCAN1,RBPJ,NCOR1,KDM1A,MYB |
| 5.518e-03 | -5.20 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | 279 | 51 | 17758 | 2279 |
EP400,TRIM16,XPC,TCF3,SLC29A1,SLC6A8,SEC16A,MAP2K3,PCDH7,CAD,RNFT2,NPRL2,PI4KB,MYC,NISCH,UBAP2L,PMPCA,KDM5C,AMOT,LPCAT1,SCAF11,SKIV2L,DBN1,FADS1,FLNC,PRAME,LAMC1,MYO10,ARHGEF10,ATXN1,BRCA1,AKAP13,MEN1,MAT2A,NCDN,POLR2A,ECH1,PEX1,LSS,AHNAK,INSIG1,FSCN1,CDK9,VCAN,CLEC16A,FTSJ1,SQLE,MYOM2,DHCR7,LAMA5,BAG1 |
| 5.521e-03 | -5.20 | CCAR2 (cell cycle and apoptosis regulator 2) | protein interactions | 57805 | 89 | 22 | 16036 | 2270 |
KAT8,DCTN3,TUBA1A,FN1,SIRT6,SIRT7,METTL23,BRCA1,GBF1,RPA1,RARS,NEK6,CDK9,MYC,COPS5,IKBKB,PRMT5,ACTR3B,PNMA1,CEP170,HTRA2,EMSY |
| 5.521e-03 | -5.20 | ACIN1 (apoptotic chromatin condensation inducer 1) | protein interactions | 22985 | 89 | 22 | 16036 | 2270 |
SLC3A2,CUL7,UTP14A,SIRT7,ZC3H18,NFIA,CSNK2A1,CAV1,EVPL,PRKCA,SON,RHOT2,SUB1,BCAS2,BANF1,RNF2,BMI1,SRRM2,SRP14,SRPK2,SF3A1,CLK2 |
| 5.527e-03 | -5.20 | cellular catabolic process | biological process | GO:0044248 | 1338 | 205 | 16441 | 2138 |
GGT1,CYP24A1,CUL7,CUL4A,PRDX6,DCP1B,SLC25A21,HECTD3,RCHY1,RNF43,SIRT2,GYG1,NT5C3A,HMOX2,ABHD6,BIRC2,UBR5,LPIN1,PABPC4,EDC3,TOM1L1,PCYOX1L,ANAPC1,AMPD3,RPS16,PMAIP1,PHKA1,ANAPC11,ANAPC10,HYAL1,RNF111,OGG1,PPM1K,LONP1,PRKACB,MPST,ACADS,TRIM13,RBCK1,SESN2,FBXW4,SKIV2L2,ITPA,UPP1,ALDH1L2,HSPA5,GPCPD1,TCEB3,DLST,SPOP,KIF16B,GLS,HPRT1,DDAH2,BDH2,XPNPEP1,NOCT,USP15,CHMP4C,XYLB,FBXO45,DROSHA,UBXN1,PIK3R4,HSD17B10,TATDN3,SMG7,ZFP36L1,CCDC47,PARN,ETFB,RNF40,UBE3A,COPS3,PDE10A,PNPLA3,CNOT4,AGL,PABPC1,NT5E,EXOSC2,WDR61,PDE4A,USP49,PPAT,PCCA,EIF4A2,RNH1,USP10,PSMA1,CPT1A,ACOXL,USP46,HERPUD1,ISG15,ARIH2,UBE2E1,CAT,DAGLA,POP1,KPNA1,RPL28,UBAP1,VCAN,ZCCHC6,DPEP1,DTD1,PEX13,CNOT6,TBL1X,C18orf25,PDE9A,AGO3,CPT1C,USP7,SDSL,CYLD,PAPD4,LIN28B,RPS29,PPP2R2A,RIPK1,RNF24,DENND3,TNKS1BP1,PDE3A,DECR1,UBR1,ERI1,UCHL5,LPIN2,SOCS6,TTC3,ETF1,NT5C,HIBCH,MGLL,HTRA2,AUP1,TMLHE,PRPF19,MCEE,SKIV2L,RAB7A,MARCH6,ENC1,EDEM2,NUDT15,UBR4,USP36,PDE8B,FBXL5,CDC16,DCXR,ARNTL,USP11,MUTYH,SMG1,DMGDH,BCKDK,AUH,PDE4B,MLH1,RNASEH2B,PSMF1,NEDD4,DCTPP1,ADH5,PEX7,PHYKPL,UPF2,NLGN3,EXOSC4,FBXO31,ERI3,NT5M,FBXL19,DIS3L2,VPS37A,USP42,DHX34,PDE2A,EXOG,UBE2K,PDE3B,MMAA,NAPEPLD,NEU1,SMPDL3B,UBC,ECH1,CTIF,FBXO21,ETFDH,PXDN,ACOX1,SRD5A3,CUL2,USP20,ATM,NCBP2,TATDN1,ANAPC4,DDIT3,GCSH |
| 5.529e-03 | -5.20 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 877 | 138 | 17775 | 2278 |
TRPM6,CSNK2A1,STK33,PRKCA,MAP2K3,ABL2,NEK6,ZFHX3,MYH3,PPCDC,RNF111,SRRM2,CDK6,PRKACB,CEP128,SRPK2,FAM184A,DTNB,TNK2,TRIM13,NRAS,EXOC6B,CDK4,KSR2,SGK2,KCNH2,DYRK1B,AHNAK,TRRAP,CHD3,SEMA3C,RIOK1,ASB3,RFXAP,RNF214,MCM6,ANKRD17,TAF1,CLK1,UBXN1,TRIO,PIK3R4,TGFBR2,PITPNM1,PRKCE,TECTA,SIPA1L3,ATIC,MAP3K12,ATP6V0D1,SAMD3,SIK3,CAMKK2,BCS1L,OBSCN,ARID1A,SYT1,ZNF850,ZNF655,VPS13C,ATAD5,ZZEF1,RIOK3,DHCR7,TBCK,PDSS2,MAP2K4,DDX18,ARID2,PDK4,DDR2,RIPK1,SMARCA4,PLEK2,RADIL,URB1,RPGRIP1L,RIOK2,DECR1,PRKD3,RPS6KL1,IKBKB,ZNF142,INTS12,ADCK4,MET,CDK12,LYST,PRAME,PHLDB2,ZCCHC14,BRD4,PDK1,STK10,UBR4,FGFR1,RAB10,ZBTB25,ARMC4,RANBP2,CAMK2D,HIPK2,ABHD3,CEBPZ,RPS6KB1,HEATR1,SMG1,TMEM33,BCKDK,TNIK,BRAF,MAP3K13,CAMK1,TCF3,TRIM22,CSNK1A1,PRKCH,ZNF239,ABL1,PTRF,CLK2,RPS6KB2,LRRIQ1,KDM5A,ANKMY2,LDHA,METTL23,TEX14,PEAR1,SYMPK,RERE,OXSR1,TRIB3,ATM,MYOM2,RPS6KC1,ZAK,STK4 |
| 5.529e-03 | -5.20 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 877 | 138 | 17775 | 2278 |
TRPM6,CSNK2A1,STK33,PRKCA,MAP2K3,ABL2,NEK6,ZFHX3,MYH3,PPCDC,RNF111,SRRM2,CDK6,PRKACB,CEP128,SRPK2,FAM184A,DTNB,TNK2,TRIM13,NRAS,EXOC6B,CDK4,KSR2,SGK2,KCNH2,DYRK1B,AHNAK,TRRAP,CHD3,SEMA3C,RIOK1,ASB3,RFXAP,RNF214,MCM6,ANKRD17,TAF1,CLK1,UBXN1,TRIO,PIK3R4,TGFBR2,PITPNM1,PRKCE,TECTA,SIPA1L3,ATIC,MAP3K12,ATP6V0D1,SAMD3,SIK3,CAMKK2,BCS1L,OBSCN,ARID1A,SYT1,ZNF850,ZNF655,VPS13C,ATAD5,ZZEF1,RIOK3,DHCR7,TBCK,PDSS2,MAP2K4,DDX18,ARID2,PDK4,DDR2,RIPK1,SMARCA4,PLEK2,RADIL,URB1,RPGRIP1L,RIOK2,DECR1,PRKD3,RPS6KL1,IKBKB,ZNF142,INTS12,ADCK4,MET,CDK12,LYST,PRAME,PHLDB2,ZCCHC14,BRD4,PDK1,STK10,UBR4,FGFR1,RAB10,ZBTB25,ARMC4,RANBP2,CAMK2D,HIPK2,ABHD3,CEBPZ,RPS6KB1,HEATR1,SMG1,TMEM33,BCKDK,TNIK,BRAF,MAP3K13,CAMK1,TCF3,TRIM22,CSNK1A1,PRKCH,ZNF239,ABL1,PTRF,CLK2,RPS6KB2,LRRIQ1,KDM5A,ANKMY2,LDHA,METTL23,TEX14,PEAR1,SYMPK,RERE,OXSR1,TRIB3,ATM,MYOM2,RPS6KC1,ZAK,STK4 |
| 5.548e-03 | -5.19 | FANCI (Fanconi anemia complementation group I) | protein interactions | 55215 | 34 | 11 | 16036 | 2270 |
CAMKK2,NEK6,RAD18,PRKAB2,MYC,SIRT7,FANCD2,FAN1,ATM,IMPDH2,USP36 |
| 5.548e-03 | -5.19 | FDPS (farnesyl diphosphate synthase) | protein interactions | 2224 | 34 | 11 | 16036 | 2270 |
SEC31A,GARS,NME1-NME2,EIF4ENIF1,STAMBP,TTC38,G6PD,ATXN1,PABPC1,HNRNPA3,FGFR1 |
| 5.548e-03 | -5.19 | STAG2 (stromal antigen 2) | protein interactions | 10735 | 34 | 11 | 16036 | 2270 |
SNU13,EXOSC2,STAG1,SSU72,KDM2A,NSMCE2,SIRT7,PDS5B,HDAC8,SRRM2,BZW2 |
| 5.548e-03 | -5.19 | ZC3H11A (zinc finger CCCH-type containing 11A) | protein interactions | 9877 | 34 | 11 | 16036 | 2270 |
USP7,CUL7,TXLNG,TRA2A,SIRT7,RAPGEF4,PQBP1,BRCA1,MLH1,SERPINH1,BMI1 |
| 5.557e-03 | -5.19 | Nuclear Envelope Breakdown | REACTOME pathways | R-HSA-2980766 | 50 | 14 | 8202 | 1117 |
RANBP2,NEK6,NUP133,LEMD3,BANF1,LPIN2,NUP43,PRKCA,NUP160,NUP214,POM121,LPIN1,SEH1L,TMPO |
| 5.574e-03 | -5.19 | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | 158 | 32 | 17758 | 2279 |
MCM6,MCM10,DDX19A,DBF4,SLC29A1,AARS,NEDD4,DCTPP1,ZNF358,VPS72,MCM5,MMP14,ANP32B,RAN,PCK2,TRIP13,CTC1,TMPO,NUDC,RFC3,PSAT1,GPHN,TUBA1A,POLA1,HAUS6,LDHA,WDHD1,RPA1,ATP5D,BRCA2,MTHFD2,H2AFX |
| 5.595e-03 | -5.19 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 312 | 56 | 17758 | 2279 |
SEPHS2,GGT1,SPRED2,FAM208B,CLSTN2,MED13L,RNF24,REEP5,ETFB,PCDH7,NAMPT,MTUS1,RTN1,RNF141,PDZD2,ABCA12,PMAIP1,RABGAP1L,IKBKB,GREB1,S100A14,PNMA1,PCSK6,FDFT1,MPP6,EVL,NRAS,KRT7,TSTA3,MYO10,KCNMA1,MINA,SMARCD3,OASL,POLG2,NUDT15,PIK3CB,SMAD3,DDAH2,HPRT1,MSX2,RBBP8,PDLIM1,G6PD,TBX3,PAM,ADAM9,FKBP5,CLU,TBL1X,BMI1,DHCR7,ECHDC1,BAG1,TRIM36,GALE |
| 5.595e-03 | -5.19 | V$FOXJ2_02 | MSigDB lists | V$FOXJ2_02 | 221 | 42 | 17758 | 2279 |
SSH2,ID1,TRERF1,PAFAH1B1,NDUFB5,PDE4B,PBX1,FOXP1,NRF1,PDZD2,PVRL3,FSIP2,ANAPC11,TTC3,CHD2,CDK6,SOBP,NRAS,TUBA1A,TXLNG,CRIM1,TEAD1,NFIA,SATB2,PRDM1,R3HDM2,ZNF407,PHF6,UBE2E1,NR2F1,C1orf122,SLC39A14,LRP1B,GSTO2,KIAA0355,ARNTL,CSMD3,DLX2,MBD6,BMI1,IPO4,CTXN1 |
| 5.611e-03 | -5.18 | DBF4B (DBF4 zinc finger B) | protein interactions | 80174 | 13 | 6 | 16036 | 2270 |
MAP1S,FUS,EVA1C,E2F4,KDM1A,SRPK2 |
| 5.611e-03 | -5.18 | CNN1 (calponin 1, basic, smooth muscle) | protein interactions | 1264 | 13 | 6 | 16036 | 2270 |
PRKCE,TNNC1,DNMBP,MTHFD1L,TPM1,MTHFD1 |
| 5.612e-03 | -5.18 | ANNEXIN | prints domains | PR00196 | 13 | 5 | 4759 | 462 |
ANXA5,ANXA2,ANXA7,ANXA1,ANXA10 |
| 5.634e-03 | -5.18 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | molecular function | GO:0016646 | 18 | 7 | 16491 | 2164 |
MTHFD2,MTHFD1L,MTHFD2L,ALDH1L2,PYCRL,MTHFD1,PYCR1 |
| 5.634e-03 | -5.18 | RNA polymerase III activity | molecular function | GO:0001056 | 18 | 7 | 16491 | 2164 |
CRCP,POLR3D,POLR3B,POLR1C,POLR3A,POLR3E,POLR3G |
| 5.637e-03 | -5.18 | ribonucleoprotein granule | cellular component | GO:0035770 | 141 | 29 | 17570 | 2233 |
DDX28,TUBA1A,BTBD2,DCP1B,AGO2,MEX3A,MEX3B,HNRNPA3,MBNL1,PABPC4,EDC3,YTHDF2,DDX3X,EIF4ENIF1,RPL28,LSM14A,ATXN2,ARNTL,PQBP1,EIF2S1,IGF2BP1,LARP4B,NOCT,PABPC1,AGO3,MAPT,DIS3L2,TNRC6A,TOP1 |
| 5.645e-03 | -5.18 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 202 | 39 | 17758 | 2279 |
DMXL2,HMGA2,TNIK,ADAM19,SEC24D,C16orf45,SMAD7,PID1,PABPC1L,ZNF239,CHN1,HR,STC2,MMP14,PRICKLE2,ARHGAP1,CEP135,CD44,NRIP1,MOSPD1,ELOVL6,PRDM1,GPNMB,EHBP1,DKK1,OSBPL1A,DCBLD2,IRS1,CAMK2D,GATA6,VCAN,SLC4A7,SVIL,RIOK1,SEMA3C,NRP1,NR2F2,TSPAN5,TMEM158 |
| 5.674e-03 | -5.17 | IMP metabolic process | biological process | GO:0046040 | 14 | 6 | 16441 | 2138 |
ADSL,HPRT1,AMPD3,GART,PPAT,ATIC |
| 5.675e-03 | -5.17 | pigment biosynthetic process | biological process | GO:0046148 | 47 | 13 | 16441 | 2138 |
HPRT1,GART,ALAD,PPAT,CPOX,UROD,GPR143,APRT,HMBS,COX10,FXN,TMEM14C,PRPS1 |
| 5.675e-03 | -5.17 | regulation of mitotic sister chromatid separation | biological process | GO:0010965 | 47 | 13 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,NSMCE2,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 5.675e-03 | -5.17 | ventricular cardiac muscle tissue development | biological process | GO:0003229 | 47 | 13 | 16441 | 2138 |
FKBP1A,TNNC1,PTCD2,DLL4,DSG2,TBX3,SMAD7,ID2,RYR2,RBPJ,TPM1,DSP,FOXC1 |
| 5.690e-03 | -5.17 | ZINC_FINGER_C2H2_1 | prosite domains | PS00028 | 754 | 119 | 11866 | 1504 |
ZNF254,ZNF292,ZNF706,ZNF76,ZNF516,TRERF1,ARID2,ZBTB37,ZNF107,ZNF83,ZNF709,ZNF44,ZNF121,EEA1,ZSCAN5A,ZNF37A,ZNF804A,ZNF827,ZBTB21,ZNF608,ZFHX3,IKZF5,ZKSCAN1,JAZF1,HKR1,ZNF142,ZEB1,WIZ,ZFP37,ZNF148,ZNF85,ZNF460,ZNF3,PRMT3,ZNF646,ZBTB17,DPF3,ZNF124,AEBP2,ZNF195,ZNF680,ZNF414,ZNF480,ZSCAN2,ZNF91,ZNF251,ZNF197,ZBTB25,GZF1,ZNF266,RBSN,IKZF4,ADNP,ZNF557,KLF4,ZNF333,ZNF236,ZNF81,HIC2,ZNF436,ZNF18,ZNF397,ZBTB11,ZNF598,ZNF589,ZNF532,ZNF507,ZNF786,EGR1,DPF2,ZNF280C,MYNN,ZIC2,ZNF691,ZNF346,RLF,FOXP1,POGZ,ZNF594,ZNF483,ZNF239,ZNF358,ZNF354A,ZNF586,ZNF561,ZNF710,ZNF518B,ZNF629,TSHZ1,ZNF675,ZNF234,RREB1,ZNF821,ZNF587,PRDM16,ZNF654,ZFP14,ZNF512B,ZNF324B,PRDM1,APTX,ZNF467,ZNF407,KLF6,ZNF850,ZNF655,ZNF221,ZNF708,ZFP62,ZNF425,ZNF155,ZBTB12,ZCCHC6,ZNF160,ZNF430,ZFP90,ZNF32,ZFHX2,ZBTB24 |
| 5.707e-03 | -5.17 | negative regulation of cell division | biological process | GO:0051782 | 74 | 18 | 16441 | 2138 |
TEX14,CSNK2A1,MAD2L2,UBE2E1,TOM1L1,KLHL22,ANAPC1,CDC16,TOM1L2,MYC,ANAPC11,ANAPC10,MAD1L1,ATM,BMP4,DMRT1,ANAPC4,CHMP4C |
| 5.710e-03 | -5.17 | AR (androgen receptor) | protein interactions | 367 | 272 | 54 | 16036 | 2270 |
NCOR2,FOXO1,TAF1,RCHY1,SMARCA4,RAC3,PELP1,HSPA1A,KDM1A,TADA3,RNF40,UBE3A,PPID,NISCH,GTF2H1,MED24,RNF2,RAN,NRIP1,CDK6,CDC37,GTF2H3,TNK2,PXN,RREB1,KDM5B,PSPC1,JMJD1C,PSMC3IP,POU2F1,USP10,CAV1,BRCA1,SETD7,TCF7L2,SPOP,SMAD3,NSD1,SRCAP,MYBBP1A,SMARCC1,PMEPA1,HIF1A,CDK9,E2F4,CUL2,SVIL,FKBP5,NCOR1,MDN1,RUNX1,BMI1,MID1,BAG1 |
| 5.714e-03 | -5.16 | Type 2 diabetes(PMID:18372903) | GWAS genes | Type 2 diabetes(PMID:18372903) | 8 | 5 | 2389 | 419 |
CDKAL1,IGF2BP2,THADA,JAZF1,TCF7L2 |
| 5.717e-03 | -5.16 | HSPA5 (heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)) | protein interactions | 3309 | 308 | 60 | 16036 | 2270 |
DNAJC2,SART1,INSIG2,CUL7,DNAJA4,BRAF,CUL4A,FN1,UPK3B,DPH1,UBXN1,ID2,MYH9,PCSK7,TMEM132A,HSPA1A,HNRNPA3,AMBRA1,SNW1,SUB1,RPS16,SHC1,ZSWIM7,SREBF2,UCHL5,FMNL1,SHMT2,RMDN3,SSBP1,SERPINH1,AHCYL1,VCL,SRRM2,SPTAN1,RPS6KB2,DDX24,RAB7A,LGALS1,METTL23,RAP1GDS1,METTL22,CPT1A,UBC,CLNS1A,RPA1,STOML2,PWP1,HNRNPR,TRAP1,DNAJC1,CDK9,COPS5,CAMKMT,CUL2,H2AFX,SIL1,FUS,CLU,COPS6,LPP |
| 5.720e-03 | -5.16 | V$NF1_Q6 | MSigDB lists | V$NF1_Q6 | 247 | 46 | 17758 | 2279 |
IMMP2L,HMGA2,JUP,RBFOX2,TNXB,LPCAT3,SSBP2,GDPD5,RPS6KA5,MBNL1,BMP6,CAMTA2,MCAM,JAZF1,TANK,ZNF148,NLGN3,WNT16,ZMYM2,SOBP,EXOSC2,BDNF,SESN2,IL11RA,STAG1,WDPCP,NFIA,ATG12,SOX4,KCNH2,KRTCAP2,MBNL2,MGST1,RERE,EXOC6,CACNB1,ZBTB8OS,SIX5,ZNF436,CSRNP1,TRMT2A,SEMA3C,RUNX1,MID1,PRKAR2A,MEF2C |
| 5.749e-03 | -5.16 | PML body | cellular component | GO:0016605 | 93 | 21 | 17570 | 2233 |
USP7,TRIM16,UBN1,WDFY3,ATRX,TOP3A,SUMO3,RPAIN,TCF7L2,SKI,RPA1,SKIL,EIF4ENIF1,SRSF2,CDK9,HIPK2,NSMCE2,ARNTL,ZMYM2,CASP8AP2,KAT6A |
| 5.765e-03 | -5.16 | endoribonuclease activity, producing 5'-phosphomonoesters | molecular function | GO:0016891 | 27 | 9 | 16491 | 2164 |
RPP30,POP1,EXO1,DROSHA,APEX1,AGO2,POP5,RNASEH2B,EDC3 |
| 5.765e-03 | -5.16 | oxidoreductase activity, acting on the CH-NH group of donors | molecular function | GO:0016645 | 27 | 9 | 16491 | 2164 |
DMGDH,ETFDH,MTHFD2,ALDH1L2,PYCRL,MTHFD1L,MTHFD2L,PYCR1,MTHFD1 |
| 5.772e-03 | -5.15 | KCCGNSWTTT_UNKNOWN | MSigDB lists | KCCGNSWTTT_UNKNOWN | 98 | 22 | 17758 | 2279 |
SPRED2,PTBP2,PAFAH1B1,RFX1,EIF4A2,GRHL3,NHS,POU2F1,CSNK1A1,FOXO3,GABPB2,UBC,IGF2BP3,RGS17,SYNCRIP,KDM2A,ATP5G2,ADNP,RBPJ,CELF1,WDR33,DMTF1 |
| 5.778e-03 | -5.15 | REACTOME_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | REACTOME_UNFOLDED_PROTEIN_RESPONSE | 75 | 18 | 17758 | 2279 |
ZBTB17,EXOSC2,ATF4,CUL7,HSPA5,PARN,SERP1,HERPUD1,SRPRB,SEC31A,YIF1A,ASNS,SHC1,EIF2S1,EXOSC4,ATP6V0D1,DDIT3,MBTPS2 |
| 5.778e-03 | -5.15 | CCGNMNNTNACG_UNKNOWN | MSigDB lists | CCGNMNNTNACG_UNKNOWN | 75 | 18 | 17758 | 2279 |
TTPAL,RFC4,SUPT6H,NSUN6,MRRF,MFHAS1,CAD,DDX50,SYNCRIP,HERC1,AP1M1,PTRH2,ADCK4,CNOT4,ZBTB11,TXN2,ANKS1A,PRKACB |
| 5.778e-03 | -5.15 | MORF_CCNF | MSigDB lists | MORF_CCNF | 75 | 18 | 17758 | 2279 |
SPRED2,LARS2,SIGMAR1,POLA1,BMS1,MARS,BRCA1,HLTF,TTI1,EIF5B,TIMM44,MFN2,TAF2,RAP1A,MSH3,SYNJ2,TRIP13,SMG1 |
| 5.798e-03 | -5.15 | PRPF19 (pre-mRNA processing factor 19) | protein interactions | 27339 | 133 | 30 | 16036 | 2270 |
SART1,CUL7,APEX1,FN1,UTP14A,SMARCAD1,PLRG1,UBXN1,SF3A3,SON,UBC,POLR2A,RPA1,SNW1,KPNA1,CTNNBL1,BCAS2,UCHL5,COPS5,BUD31,LTN1,PRPF4,RNF2,SRRM2,SRP14,MTCH1,HNRNPM,SF3A1,MTHFD1,PRPF19 |
| 5.805e-03 | -5.15 | DBF4 (DBF4 zinc finger) | protein interactions | 10926 | 21 | 8 | 16036 | 2270 |
MCM6,RAD18,ORC5,DBF4,BRCA1,MCM2,MEN1,CHAF1A |
| 5.805e-03 | -5.15 | GNL1 (guanine nucleotide binding protein-like 1) | protein interactions | 2794 | 21 | 8 | 16036 | 2270 |
PES1,PTP4A1,KPNA3,DDX18,RANGAP1,EIF5B,NOP58,PABPC4 |
| 5.805e-03 | -5.15 | NAPG (N-ethylmaleimide-sensitive factor attachment protein, gamma) | protein interactions | 8774 | 21 | 8 | 16036 | 2270 |
STX8,FN1,NSF,SCFD2,NAPA,MTR,AKAP11,PRKACB |
| 5.805e-03 | -5.15 | SESTO_RESPONSE_TO_UV_C2 | MSigDB lists | SESTO_RESPONSE_TO_UV_C2 | 53 | 14 | 17758 | 2279 |
JAG1,IFNGR2,TSTA3,ZKSCAN1,HIF1A,FAT1,PCMT1,PTPN12,USP11,NRIP1,TOP1,CXADR,KAT6A,SRPK2 |
| 5.806e-03 | -5.15 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 393 | 68 | 17775 | 2278 |
CDCP1,MVK,PDK4,CSNK2A1,PRKCA,MAP2K3,ABL2,RPS6KL1,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,TNK2,PDK1,CDK4,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,BRCA2,HIPK2,RPS6KB1,TROVE2,HMGA2,SEPHS2,TNIK,BRAF,AK2,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,PRKCH,ABL1,PI4KB,GTF2H1,ALDH18A1,MAP3K12,RPS6KB2,CAMKK2,CRIM1,RB1CC1,PALLD,PIK3CB,CENPP,TRIB3,HK2,ATM,RPS6KC1,PDLIM5,MAP2K4,PRKAR2A,DDIT3 |
| 5.806e-03 | -5.15 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 393 | 68 | 17775 | 2278 |
CDCP1,MVK,PDK4,CSNK2A1,PRKCA,MAP2K3,ABL2,RPS6KL1,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,TNK2,PDK1,CDK4,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,BRCA2,HIPK2,RPS6KB1,TROVE2,HMGA2,SEPHS2,TNIK,BRAF,AK2,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,PRKCH,ABL1,PI4KB,GTF2H1,ALDH18A1,MAP3K12,RPS6KB2,CAMKK2,CRIM1,RB1CC1,PALLD,PIK3CB,CENPP,TRIB3,HK2,ATM,RPS6KC1,PDLIM5,MAP2K4,PRKAR2A,DDIT3 |
| 5.806e-03 | -5.15 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 393 | 68 | 17775 | 2278 |
CDCP1,MVK,PDK4,CSNK2A1,PRKCA,MAP2K3,ABL2,RPS6KL1,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,TNK2,PDK1,CDK4,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,BRCA2,HIPK2,RPS6KB1,TROVE2,HMGA2,SEPHS2,TNIK,BRAF,AK2,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,PRKCH,ABL1,PI4KB,GTF2H1,ALDH18A1,MAP3K12,RPS6KB2,CAMKK2,CRIM1,RB1CC1,PALLD,PIK3CB,CENPP,TRIB3,HK2,ATM,RPS6KC1,PDLIM5,MAP2K4,PRKAR2A,DDIT3 |
| 5.806e-03 | -5.15 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 393 | 68 | 17775 | 2278 |
CDCP1,MVK,PDK4,CSNK2A1,PRKCA,MAP2K3,ABL2,RPS6KL1,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,TNK2,PDK1,CDK4,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,BRCA2,HIPK2,RPS6KB1,TROVE2,HMGA2,SEPHS2,TNIK,BRAF,AK2,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,PRKCH,ABL1,PI4KB,GTF2H1,ALDH18A1,MAP3K12,RPS6KB2,CAMKK2,CRIM1,RB1CC1,PALLD,PIK3CB,CENPP,TRIB3,HK2,ATM,RPS6KC1,PDLIM5,MAP2K4,PRKAR2A,DDIT3 |
| 5.806e-03 | -5.15 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 393 | 68 | 17775 | 2278 |
CDCP1,MVK,PDK4,CSNK2A1,PRKCA,MAP2K3,ABL2,RPS6KL1,CMPK1,MET,FXN,KMT2A,ZMYM2,CDK6,PRKACB,SRPK2,TNK2,PDK1,CDK4,KSR2,AKAP13,GALK2,SOX4,STK10,FGFR1,BRCA2,HIPK2,RPS6KB1,TROVE2,HMGA2,SEPHS2,TNIK,BRAF,AK2,FOXO1,MAP3K13,CLK1,TRIO,DBF4,PIK3R4,MAPK8IP3,ATF7IP,IP6K2,IKBKAP,TGFBR2,CSNK1A1,FOXO3,PRKCH,ABL1,PI4KB,GTF2H1,ALDH18A1,MAP3K12,RPS6KB2,CAMKK2,CRIM1,RB1CC1,PALLD,PIK3CB,CENPP,TRIB3,HK2,ATM,RPS6KC1,PDLIM5,MAP2K4,PRKAR2A,DDIT3 |
| 5.810e-03 | -5.15 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | 196 | 38 | 17758 | 2279 |
POLB,TRAK1,CHCHD10,RNASEH2B,LCLAT1,DDIT4,DECR1,IDI1,NVL,PDS5B,ELOF1,TMPO,HMGCR,FDFT1,RFC4,PRIM2,SKAP2,MINA,LGALS1,RNH1,BRCA1,CYB5B,TRIM37,TAMM41,AHNAK,HSDL2,LUC7L3,FDPS,HK2,SQLE,CRCP,NCBP2,ANXA2,NDUFS5,RBPJ,HMBS,DHCR7,BLMH |
| 5.841e-03 | -5.14 | regulation of DNA-templated transcription, elongation | biological process | GO:0032784 | 42 | 12 | 16441 | 2138 |
PAF1,ELL,THOC5,BRD4,SUPT4H1,WDR61,SUPT6H,ZNF326,CTR9,NELFA,SUPT5H,CDC73 |
| 5.857e-03 | -5.14 | SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit) | protein interactions | 11198 | 111 | 26 | 16036 | 2270 |
SNU13,POLB,CUL7,ATRX,POLR1A,SMARCAD1,ZC3H18,CSNK2A1,BRCA1,KRI1,PES1,PAF1,APLF,FMNL1,CDK9,H2AFX,CTR9,RNF2,BRCC3,BMI1,POLR1E,CDK12,HNRNPM,TOP1,SRPK2,SF3A1 |
| 5.872e-03 | -5.14 | histone deacetylase complex | cellular component | GO:0000118 | 59 | 15 | 17570 | 2233 |
GATAD2B,DNTTIP1,NCOR2,HR,CHD3,MBD2,CSNK2A1,HDAC8,SATB2,NCOR1,TBL1X,NRIP1,CHD5,RERE,SAP30 |
| 5.893e-03 | -5.13 | translation initiation factor activity | molecular function | GO:0003743 | 52 | 14 | 16491 | 2164 |
EIF4E3,EIF2S2,EIF3C,EIF3J,MTIF2,COPS5,EIF4A2,AGO2,EIF2S1,EIF2A,EIF2B3,EIF5B,EIF3H,DENR |
| 5.893e-03 | -5.13 | DNA strand elongation involved in DNA replication | biological process | GO:0006271 | 37 | 11 | 16441 | 2138 |
RFC4,MCM6,RFC3,GINS3,PRIM2,APEX1,MCM5,POLA1,LIG4,MCM2,RPA1 |
| 5.920e-03 | -5.13 | apoptotic signaling pathway | biological process | GO:0097190 | 368 | 65 | 16441 | 2138 |
SART1,POLB,CUL4A,NF1,TNFRSF21,TMEM109,RIPK1,CHAC1,PRKCA,BLOC1S2,PMAIP1,FNIP2,FHIT,CASP10,PERP,CASP8AP2,HTRA2,TIMM50,ATF4,PDK1,PARP2,MCL1,SHISA5,AKAP13,BRCA1,CAV1,SMAD3,DDX3X,ZNF622,BRCA2,HIPK2,ARL6IP5,TNFRSF1A,PPP3CC,FIS1,CLU,TNFRSF10D,ZMAT3,MAPT,DPF2,TRIO,CDIP1,MLH1,TGFB2,NOL3,ZNF346,FOXO3,DDIT4,ABL1,SNW1,CRADD,OBSCN,ARHGEF12,IL6R,RHOT2,UBE2K,UBC,TRIB3,MYBBP1A,CUL2,AEN,ATM,APAF1,BRSK2,DDIT3 |
| 5.921e-03 | -5.13 | inflammatory_myofibroblastic_tumour | COSMIC cancer mutations | inflammatory_myofibroblastic_tumour | 23 | 8 | 17775 | 2278 |
CARS,SEC31A,RANBP2,BRAF,ATIC,PPFIBP1,TPM4,FUS |
| 5.921e-03 | -5.13 | soft_tissue-fibrous_tissue_and_uncertain_origin-inflammatory_myofibroblastic_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-inflammatory_myofibroblastic_tumour | 23 | 8 | 17775 | 2278 |
CARS,SEC31A,RANBP2,BRAF,ATIC,PPFIBP1,TPM4,FUS |
| 5.927e-03 | -5.13 | CADWELL_ATG16L1_TARGETS_DN | MSigDB lists | CADWELL_ATG16L1_TARGETS_DN | 64 | 16 | 17758 | 2279 |
DNAJA4,SULT1C2,SKIV2L2,PDK4,SATB2,C15orf57,HSPA1A,HSPA1B,CAMK2D,ZNF266,PPFIBP1,PER1,C15orf40,D2HGDH,TTC3,CCDC88C |
| 5.928e-03 | -5.13 | embryonic morphogenesis | biological process | GO:0048598 | 556 | 93 | 16441 | 2138 |
DLL4,LUZP1,MYO7A,MKS1,PBX1,ENAH,SLC39A1,RPGRIP1L,SKI,CHD7,ACD,DNAJB6,MYH3,MMP14,HYAL1,ZEB1,CCDC40,RNF2,PRKACB,ZBTB17,SOBP,DEAF1,FBXW4,WLS,WDPCP,GRHL3,SATB2,MTHFD1L,SUPT20H,SOX4,TCTN1,FLVCR1,FGFR1,KIF16B,PAF1,SMAD3,MSX2,GATA6,INSIG1,HIPK2,KLF4,ITGA2,ARL13B,HOXA3,DLX2,NRP1,LAMA5,MEF2C,HMGA2,CHST11,IFT57,INSIG2,FN1,CELSR1,PAX2,ID2,ZIC2,ZFP36L1,TRIM15,LIAS,TGFBR2,CDC73,MBNL1,ZNF358,CEP290,NDRG4,CTR9,WNT16,MFAP2,DYNC2H1,AMOT,MTHFD1,TSHZ1,KDM6B,FGF9,MSX1,FGF2,FZD3,RDH10,SETD2,RYR2,ARID1A,FOXC1,TCF7L2,DKK1,HIF1A,TBX3,BMP4,APAF1,ITGB4,MMP16,STK4,HS2ST1 |
| 5.946e-03 | -5.12 | MORF_DNMT1 | MSigDB lists | MORF_DNMT1 | 116 | 25 | 17758 | 2279 |
RFC4,MCM6,GARS,SKIV2L2,KHDRBS1,R3HDM1,SF3A3,XPO7,MCM2,DKC1,TARS,HDDC2,POM121,PABPC4,CHAF1A,TRRAP,SREBF2,HNRNPR,MCM5,MRPS27,TNPO3,SSBP1,YARS,HNRNPM,NUDC |
| 5.951e-03 | -5.12 | NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | 254 | 47 | 17758 | 2279 |
ZNF254,ID1,ZHX3,RBFOX2,KHDRBS1,NFX1,ID2,ATF7IP,BCOR,SIRT2,RSF1,PAIP2,TERF2IP,SNW1,SOCS1,VPS72,JAZF1,TIMELESS,ZEB1,ZNF148,NRIP1,TERF2,KAT8,KDM5B,NR6A1,LIMA1,FOXN3,ARID5B,CUX1,ATXN1,POU2F1,HDAC8,PRDM1,BRCA1,MEN1,SUPT5H,VDR,SMAD3,NSD1,SUPT4H1,DNAJC1,KLF4,PER1,TBX3,SET,RBPJ,KAT6A |
| 5.966e-03 | -5.12 | KLF1 (Kruppel-like factor 1 (erythroid)) | protein interactions | 10661 | 17 | 7 | 16036 | 2270 |
GTF2H1,CSNK2A1,SMARCA4,ARID1A,SMARCC1,UBC,SMARCB1 |
| 5.966e-03 | -5.12 | NCBP3 (nuclear cap binding subunit 3) | protein interactions | 55421 | 17 | 7 | 16036 | 2270 |
RNF2,NIFK,BMI1,HNRNPH3,RSRC1,TRA2A,SRPK2 |
| 5.966e-03 | -5.12 | FAM13C (family with sequence similarity 13, member C) | protein interactions | 220965 | 17 | 7 | 16036 | 2270 |
PHC2,HMBOX1,AHCYL1,TFIP11,AHCYL2,CCDC85B,SDCBP2 |
| 5.966e-03 | -5.12 | METTL21C (methyltransferase like 21C) | protein interactions | 196541 | 17 | 7 | 16036 | 2270 |
DYNC1H1,BCKDK,KDM1A,HSPA5,UBC,CARM1,MAD1L1 |
| 5.966e-03 | -5.12 | POLR3E (polymerase (RNA) III (DNA directed) polypeptide E (80kD)) | protein interactions | 55718 | 17 | 7 | 16036 | 2270 |
CRCP,BCCIP,GPN1,POLR3D,POLR3B,POLR3A,POLR3G |
| 5.966e-03 | -5.12 | CLK4 (CDC like kinase 4) | protein interactions | 57396 | 17 | 7 | 16036 | 2270 |
JMJD6,SUB1,KPNA1,CLASRP,SRRM2,UBL5,AHCYL2 |
| 5.972e-03 | -5.12 | PID_NFKAPPAB_CANONICAL_PATHWAY | MSigDB lists | PID_NFKAPPAB_CANONICAL_PATHWAY | 23 | 8 | 17758 | 2279 |
CYLD,IKBKB,TNFRSF1A,ATM,RAN,PRKCA,BIRC2,ERC1 |
| 5.972e-03 | -5.12 | OXFORD_RALA_OR_RALB_TARGETS_DN | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_DN | 23 | 8 | 17758 | 2279 |
FSCN1,HK2,CLU,SLC6A8,TPM1,PALLD,PDE2A,METTL2B |
| 5.972e-03 | -5.12 | TRANSLATION_INITIATION_FACTOR_ACTIVITY | MSigDB lists | TRANSLATION_INITIATION_FACTOR_ACTIVITY | 23 | 8 | 17758 | 2279 |
EIF2S2,EIF3C,COPS5,EIF3J,EIF4A2,EIF2S1,EIF2A,EIF2B3 |
| 5.972e-03 | -5.12 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | MSigDB lists | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | 23 | 8 | 17758 | 2279 |
UBTF,GTF2H3,RRN3,EHMT2,POLR1A,GTF2H1,POLR1B,POLR1C |
| 5.974e-03 | -5.12 | GSE17721_0.5H_VS_12H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDM_UP | 190 | 37 | 17758 | 2279 |
MYCBP2,HM13,TNFRSF21,FOXP1,LCLAT1,PELP1,SCAF8,ANKRD54,ARMC6,UCHL5,PYCRL,C15orf40,METTL8,ALDH18A1,C6orf89,ATP6V0D1,KIAA1143,CMIP,SFSWAP,TTYH2,GALK2,NHSL1,ENC1,SLC50A1,SAP30BP,MRPL36,MGAT2,DDX3X,HLA-DMA,HPRT1,RPL28,PEMT,FDPS,H2AFX,LARGE,NOLC1,IPO4 |
| 5.974e-03 | -5.12 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP | 190 | 37 | 17758 | 2279 |
SART1,ACTG1,PDK4,ZFP36L1,SAFB2,AMBRA1,PABPC4,DDIT4,SLC25A20,FARSA,NDUFV1,SOCS1,BANF1,SLC39A7,COPS7B,TSPAN14,CDC37,NRAS,LSM12,HSPA5,WDR18,MARCKSL1,RABAC1,ATP8B2,ABCF1,HERPUD1,MFN2,ATP5D,SEC31A,DDX3X,NSD1,TPD52L2,ZDHHC11,HNRNPR,CDK9,SVIL,FKBP5 |
| 5.974e-03 | -5.12 | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN | 190 | 37 | 17758 | 2279 |
BCKDK,SCAMP3,STX8,TFIP11,DPM3,GRINA,VARS,AARS,FLNB,SMARCB1,NAMPT,NDUFV1,SOCS1,BUD31,ZEB1,RAN,PPA1,LYPLA2,COL5A2,UPP1,PSMC3IP,CPOX,WDHD1,MARS,PITPNB,MCM2,C8orf33,C19orf70,HSD3B7,WARS,HLA-DMA,FDPS,PQBP1,DPP4,NRP1,KIF1B,PKIB |
| 5.974e-03 | -5.12 | GSE14308_INDUCED_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_INDUCED_VS_NATURAL_TREG_UP | 190 | 37 | 17758 | 2279 |
CUL4A,SUCLG1,RCAN1,LIAS,EVPL,RPAIN,SLC39A1,EDC3,BLOC1S2,ZNF239,KCTD11,SLX4,ZSWIM7,CNIH3,THAP4,ATP5G2,UNC13A,DTNBP1,CD44,ATP6V0D1,SF3A1,TTLL5,SCFD2,MAPK1IP1L,PTK2,ENC1,SLC9A5,ERC1,CLNS1A,MFN2,WARS,YIF1A,OXSR1,DNAJC12,TAF12,MUTYH,METTL2B |
| 5.974e-03 | -5.12 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDM_UP | 190 | 37 | 17758 | 2279 |
ZNF706,NDUFA5,DNAJC2,SEC24D,ST6GAL1,OLA1,LAMTOR3,APRT,MRPS11,SACS,HVCN1,ATP5G2,CPSF3,FBXO31,LYRM5,AHCYL1,CTC1,C12orf4,NUDC,FADS1,FAM127A,SKIV2L2,IDH3G,XPO5,MRRF,IMPDH2,TPRA1,EHBP1,EVI5,HERPUD1,PWP1,UBAP2,ALAD,COPS5,HERC1,GPAM,ANXA2 |
| 5.982e-03 | -5.12 | CDK8 (cyclin-dependent kinase 8) | protein interactions | 1024 | 79 | 20 | 16036 | 2270 |
HERC2,MED27,MED13L,SMARCA4,MED18,MED16,BRCA1,POLR2A,SMARCB1,SMAD3,TRRAP,EHMT2,SMARCC1,HIF1A,MYC,MED15,MED24,MED20,NRIP1,TOP1 |
| 5.982e-03 | -5.12 | CEBPB (CCAAT/enhancer binding protein (C/EBP), beta) | protein interactions | 1051 | 79 | 20 | 16036 | 2270 |
NCOR2,ATF4,EGR1,FOXO1,PPARG,SMARCA4,BRCA1,RPS6KA5,SMARCB1,SMAD3,NRF1,EHMT2,SMARCC1,MYC,NCOR1,RUNX1,NOLC1,CARM1,DDIT3,MYB |
| 5.987e-03 | -5.12 | human chr4q32.3 | chromosome location | human chr4q32.3 | 18 | 6 | 26250 | 2590 |
PALLD,SH3RF1,DDX60,CBR4,DDX60L,SPOCK3 |
| 6.041e-03 | -5.11 | RBM28 (RNA binding motif protein 28) | protein interactions | 55131 | 39 | 12 | 16036 | 2270 |
PES1,ZNF622,NIFK,DDX18,SIRT7,RNF2,BRCA1,DKC1,ZC3H3,POLR3G,NOP56,TOP1 |
| 6.041e-03 | -5.11 | OIP5 (Opa interacting protein 5) | protein interactions | 11339 | 39 | 12 | 16036 | 2270 |
SKIL,RNF40,ABL2,EIF4ENIF1,BRAF,TRIP6,STX1A,TFIP11,CEP170,CASP10,KDM1A,TMPO |
| 6.041e-03 | -5.11 | TPRKB (TP53RK binding protein) | protein interactions | 51002 | 39 | 12 | 16036 | 2270 |
METTL1,PRAME,TPD52L2,P3H1,ACTR3,LAGE3,RANGAP1,NUP43,PRKACB,IPO11,SH3GL1,LPP |
| 6.041e-03 | -5.11 | TNRC6B (trinucleotide repeat containing 6B) | protein interactions | 23112 | 39 | 12 | 16036 | 2270 |
FLAD1,GARS,COPS5,AGO2,CUL2,CNOT6,BMI1,PABPC1,GIGYF2,AGO3,UBC,CARM1 |
| 6.066e-03 | -5.11 | CTGAGCC,MIR-24 | MSigDB lists | CTGAGCC,MIR-24 | 222 | 42 | 17758 | 2279 |
SSH2,ADAM19,CCDC58,TRPM6,DLGAP4,IP6K2,AARS,POGZ,RAP1A,STC2,CLCN6,MMP14,RNF2,KDM5C,TSPAN14,FBXL19,LYPLA2,TOP1,CLK2,DDN,ARID5B,RAP1B,PCNXL2,MARCKSL1,MEN1,DCBLD2,BSN,DAGLA,CACNB1,KPNA3,INSIG1,LMBR1L,PER1,G6PD,RNF138,H2AFX,HIC2,CNOT6,PSAP,MBD6,MAGI1,MMP16 |
| 6.085e-03 | -5.10 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IV | 48 | 13 | 17775 | 2278 |
AHNAK,BRAF,HR,TRAP1,NF1,ATRX,PSPC1,KIAA0586,WWC1,GREB1L,ZNF407,KIAA1549,DCAF5 |
| 6.091e-03 | -5.10 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 202 | 42 | 16036 | 2270 |
TTN,SPRED2,CUL7,CYLD,MAP2K5,C10orf2,PPHLN1,RIPK1,CSNK2A1,AKT1S1,MLH1,FLNB,MYC,GTF3C3,GEMIN4,SRRM2,NIPSNAP1,CDC37,TNK2,TRIM13,SESN2,TUBA1A,PDE4A,WDFY3,CAV1,AGAP1,ISG15,UBC,CHAF1A,SNCA,SMAD3,TOE1,HIF1A,CDK9,CUL2,GLG1,ATG7,RPS6KB1,FUS,NCOR1,NR2F2,MAPT |
| 6.096e-03 | -5.10 | replisome | cellular component | GO:0030894 | 28 | 9 | 17570 | 2233 |
BCAS2,POLE2,PRIM2,POLA1,PLRG1,PURB,POLE3,RPA1,PRPF19 |
| 6.105e-03 | -5.10 | Cellular responses to stress | REACTOME pathways | R-HSA-2262752 | 379 | 69 | 8202 | 1117 |
CHMP2A,ID1,PRDX6,UBN1,PRKAB2,NUP43,NUP160,HSPA1A,RING1,MAP2K3,AMBRA1,PHC2,TERF2IP,ANAPC1,ACD,NUP133,ATG3,DNAJB6,ANAPC11,ANAPC10,RNF2,CDK6,SEH1L,ATG9A,CDK4,ATOX1,HSPA5,EHMT1,ATG12,HIST1H2BL,NUP214,RANBP2,CAMK2D,CDC16,ATG7,H2AFX,TXN2,BMI1,BAG1,TNRC6A,CHMP4C,HMGA2,TNIK,DNAJC2,EP400,MINK1,PIK3R4,LAMTOR3,AKT1S1,POM121,HIST2H3D,TERF2,KDM6B,RB1CC1,SCMH1,HIST1H4J,UBE2E1,UBC,HSPA1B,RPA1,CAT,EHMT2,HIF1A,CUL2,RRAGA,ATM,MAP2K4,AGO3,ANAPC4 |
| 6.122e-03 | -5.10 | HNRNPU (heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)) | protein interactions | 3192 | 315 | 61 | 16036 | 2270 |
SART1,CUL7,EIF3C,FN1,UTP14A,RPS29,MRPL10,NFX1,MYH9,RSL1D1,HNRNPA3,NEDD4,PCDH7,NOP56,IGF2BP3,ELL,SNW1,RPS16,MCM5,MYC,IKBKB,GTF2H1,RNF2,YBX3,SRRM2,PABPC1,FTSJ3,RPS6KB2,SF3A1,SNU13,RFC4,EIF3J,SMARCAD1,TRA2A,HSPA5,ZC3H18,WDR18,NFIA,NOP58,ABCF1,FKBP3,UBC,PHF6,POLR2A,ISG15,RPA1,DOT1L,SYNCRIP,KDM4B,LSM14A,CDK9,LUC7L3,HNRNPH3,COPS5,CUL2,GPN1,PRPF4,FUS,ITGB4,EIF2B3,MTCH1 |
| 6.134e-03 | -5.09 | AAA | smart domains | SM00382 | 144 | 31 | 9131 | 1249 |
RFC4,RFC3,ABCA3,ABCC4,KATNAL1,ABCF2,BCS1L,ABCC2,MMAA,ABCF1,MCM9,PEX1,ABCA7,DYNC1H1,ASCC3,ATAD5,NAV1,ABCA12,NVL,NSF,ABCA5,RAD51B,GPN1,ABCC3,DNAH2,DYNC2H1,MDN1,TRIP13,LONP1,VWA8,NAV3 |
| 6.137e-03 | -5.09 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_DN | 184 | 36 | 17758 | 2279 |
YDJC,ID1,SHQ1,GPBP1L1,PRPF31,PRKAB2,NAT10,PABPC4,DENR,PHF5A,NOP16,VAPB,SHF,POLR1B,FXN,HCFC2,MTHFD1,SOBP,EXOSC2,TRAPPC9,APEX1,MINA,USP10,MEF2D,MTHFD1L,SYMPK,BATF3,ATP5D,PWP1,RARS,BAZ2B,RPL28,SGSM2,HEATR1,SLC16A10,RBP1 |
| 6.140e-03 | -5.09 | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP | 320 | 57 | 17758 | 2279 |
ZNF254,PTP4A1,IMMP2L,COMMD10,AOC3,SYT17,BRAF,SUCLG1,RBFOX2,CAMK1,PRSS3,PDCD5,LCLAT1,SNAPC4,TRIM66,ABL1,SRSF2,TSPAN2,ACD,TRMU,SERPINH1,PLEKHA2,DMRT1,PAQR6,TNK2,LAMC1,SSFA2,STAG1,GALK2,SNAP25,GPNMB,SOX4,DENND4A,CHCHD6,DCBLD2,ZNF266,IREB2,KPNA1,RBBP8,KIDINS220,DSC2,G6PD,LEMD3,CFD,TAF4,ZNF160,HSPB8,PQBP1,HK2,CCDC85B,PTRH2,RBM26,GPAM,TESC,RNF114,COG5,LPP |
| 6.145e-03 | -5.09 | ubiquitin ligase complex | cellular component | GO:0000151 | 270 | 49 | 17570 | 2233 |
KLHL24,CUL7,CUL4A,PLRG1,RCHY1,KLHL18,HSPA1A,MAD2L2,RING1,NEDD4,PHC2,RNF40,ANAPC1,BRE,UBR1,ATG3,ANAPC11,ANAPC10,MED24,IPP,RNF2,FBXO31,FBXL19,AUP1,FBXO17,RBCK1,FBXW4,ANAPC13,KLHL23,MED27,MARCH6,BRCA1,DCUN1D5,ENC1,ARIH2,UBE2E1,SPOP,HSPA1B,FBXL5,FBXO21,KLHL22,CDC16,RAD18,CUL2,MED20,BRCC3,BMI1,DCAF5,ANAPC4 |
| 6.148e-03 | -5.09 | STEIN_ESRRA_TARGETS | MSigDB lists | STEIN_ESRRA_TARGETS | 502 | 84 | 17758 | 2279 |
CYP24A1,SUCLG1,RBFOX2,NDUFB5,LPCAT3,TUBB6,TMEM132A,HMOX2,ZNF44,COX10,AHCYL2,FDX1,CIAPIN1,MRPS30,DECR1,AMPD3,ASNS,THAP4,INTS12,AHCYL1,CCDC121,TRIM14,TIMM50,SRPK2,FAM127A,NPM3,NOL6,WDHD1,SLC35F2,DLST,ST3GAL5,MLLT10,OSBPL1A,VDR,SLC39A14,YIPF2,SMARCC1,CLEC16A,TIMM17A,BDH2,HSPB8,MID1,MORC2,ZHX3,B4GALT5,SLK,TRIO,LETMD1,SLC25A12,ATG2B,PLA2G12A,JMJD6,GAS6,OPA1,TGFBR2,INPP1,NDUFS7,MRPS11,SLC25A20,DCTPP1,NDUFV1,SCN1B,DSG2,NDRG4,COQ3,CAV2,ZNF629,PEA15,EXOSC2,SIGMAR1,RAP1GAP2,WWC1,CPT1A,FOXC1,MFN2,ETFDH,FSCN1,COQ9,STX18,SNX24,SLC16A1,NR2F2,DDIT3,LRRC41 |
| 6.206e-03 | -5.08 | membrane docking | biological process | GO:0022406 | 69 | 17 | 16441 | 2138 |
CEP83,RAB7A,EXOC6B,SCFD2,VPS45,SNAP25,RAB10,EXOC6,VPS18,STX1A,NSF,UNC13A,EXOC4,NDRG4,PEX13,CAV2,RABEPK |
| 6.212e-03 | -5.08 | Export of Viral Ribonucleoproteins from Nucleus | REACTOME pathways | R-HSA-168274 | 31 | 10 | 8202 | 1117 |
RANBP2,NUP133,NUP43,RAN,NUP160,NUP214,HSPA1A,SEH1L,POM121,HSPA1B |
| 6.212e-03 | -5.08 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | REACTOME pathways | R-HSA-2173796 | 31 | 10 | 8202 | 1117 |
SMAD3,SNW1,CCNT1,CDK9,E2F4,MYC,SMAD7,RNF111,MEN1,UBC |
| 6.212e-03 | -5.08 | RNA Polymerase I Promoter Escape | REACTOME pathways | R-HSA-73772 | 31 | 10 | 8202 | 1117 |
UBTF,GTF2H3,RRN3,GTF2H2C,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 6.213e-03 | -5.08 | protein complex subunit organization | biological process | GO:0071822 | 1492 | 226 | 16441 | 2138 |
IMMP2L,UBN1,NF1,ATRX,PPARGC1B,AARS2,MRPL10,TRPM6,SBF2,ENAH,SIRT2,COA1,SEC16A,COX10,SYNJ1,BIRC2,CUTC,SKI,MRPS30,SMARCB1,ABL2,RPS16,NEK6,S100A10,CNIH3,ZNHIT6,WIZ,ME1,RAN,LONP1,SEH1L,ACADS,DBN1,SKAP2,LIMA1,KATNAL1,PSMG1,HIST1H2BL,CAV1,MCM2,FOXRED1,TMSB4X,MGST1,ARPC3,CHAF1A,STOML2,PAF1,GEMIN5,GLS,SKIL,HPRT1,AHNAK,CHD3,TNFRSF1A,FIS1,CLU,MAGI1,UQCC2,TTN,FN1,CDC42EP2,SEC24D,HSD17B10,RSF1,DNAH1,CHD5,SLC1A1,NDUFS7,SPIRE1,DDIT4,FKBP1A,P3H1,HR,MBD2,VPS72,MED24,ANP32B,MRPL21,CCDC88C,PRF1,CAV2,HMGCR,RANBP6,KRT20,TRAPPC9,LAMC1,PPAT,TSPYL4,SETD2,HAUS6,BCS1L,SMARCD3,SNAP25,IMPDH2,ARID1A,TRAPPC6B,SYT1,CPT1A,ANGPTL4,NAP1L5,CAT,SEC31A,DYNC1H1,EPRS,SPAG9,RPL28,NSF,FSCN1,SNAP23,FAT1,SURF1,KIAA0196,NCOR1,NAPA,SMYD3,PDSS2,VMA21,KCTD7,CHMP2A,CYLD,PCNT,ARID2,PAFAH1B1,SLC2A1,RPS29,ACTR3,C1QTNF7,TNXB,DDR2,SMARCA4,MYH9,RIPK1,COBLL1,PIBF1,PPP1R9A,BLOC1S2,NUBPL,DECR1,KCTD11,PPID,NUP133,DNAJB6,CBR4,MRPS27,CCDC40,ETF1,CORO1A,CEP63,SERPINH1,TMEM120B,KMT2A,SEC24A,EVL,MPP6,COL5A2,ASUN,C1QTNF1,PREX1,ARHGEF10,DLG4,MRRF,ATP6V0A1,VIM,DSP,ARMC4,HLA-DMA,SMAD3,CAMK2D,SMARCC1,ALAD,KPNA3,DCXR,H2AFX,MDN1,ANXA2,AP2S1,PARD3,TMEM33,NIFK,KIZ,BRAF,HM13,C10orf2,TRIM22,MLH1,CEP126,IKBKAP,TGFB2,NOL3,POGZ,GFM2,MAD2L2,MRPS11,IQGAP2,DCTPP1,PSMG4,NEBL,TMSB10,SEC24C,ANXA5,HIST2H3D,SHMT2,TTC17,ACTR3B,MICAL3,PPP1R9B,PXN,SMARCAD1,KCNMA1,MRPS10,FERMT2,ADSL,PTK2,HIST1H4J,UBE2K,FOXC1,MRPL36,CENPP,MKX,SET,NDUFAF5,NDUFS5,APAF1,UQCC1,IPO4,KAT6A |
| 6.249e-03 | -5.08 | Adipogenesis | WikiPathways | WP236 | 131 | 27 | 4455 | 564 |
NCOR2,FOXO1,PPARG,MEF2D,KLF6,MBNL1,NR2F1,LPIN1,NAMPT,PLIN2,SMAD3,IRS1,TRIB3,GADD45A,SOCS1,HIF1A,E2F4,CFD,LPIN2,BMP4,CELF1,NCOR1,PCK2,PNPLA3,NRIP1,DDIT3,MEF2C |
| 6.257e-03 | -5.07 | MITOTIC_CELL_CYCLE | MSigDB lists | MITOTIC_CELL_CYCLE | 153 | 31 | 17758 | 2279 |
DCTN3,TTN,CUL4A,TAF1,PAFAH1B1,POLA1,KHDRBS1,FOXN3,CDK4,DBF4,KIF15,TBRG4,FOXC1,MAD2L2,SMAD3,ABL1,ASNS,CDC16,NEK6,CUL2,TRIAP1,ANAPC11,ANAPC10,PAM,PDS5B,ATM,RAN,PRMT5,NOLC1,CDK6,ANAPC4 |
| 6.268e-03 | -5.07 | TTTTGAG,MIR-373 | MSigDB lists | TTTTGAG,MIR-373 | 216 | 41 | 17758 | 2279 |
USP7,PTP4A1,FN1,PAFAH1B1,ZIC2,RLF,CLINT1,IGF2BP3,RAP1A,NAV1,UBE3A,DNAJB6,WAC,SLC38A2,RELB,HARS2,ALDH18A1,SEH1L,MYB,ZCCHC14,ARID5B,DLG4,LENG8,SOX4,MBNL2,ST3GAL5,GNAI1,SLC23A2,BAZ1A,ZFAND3,ARHGAP21,KPNA3,HIF1A,LSM14A,PMEPA1,UBAP1,ZNF236,HOXA3,PURB,SH3PXD2A,TNRC6A |
| 6.277e-03 | -5.07 | CUI_TCF21_TARGETS_2_UP | MSigDB lists | CUI_TCF21_TARGETS_2_UP | 414 | 71 | 17758 | 2279 |
SRM,PRDX6,TMEM132A,CAD,ECM1,ZKSCAN1,PYCRL,MRPS27,POLE3,FXN,LAMA4,FLNC,METTL1,MPP6,RFC3,SESN2,SLC38A1,LGALS1,NFIA,SUMO3,LAMA2,PYCR1,RHOU,HLA-DMA,GATA6,RAD18,HNRNPR,SEMA3C,CLU,VASH2,RBP1,HMGA2,HM13,FN1,CELSR1,MEX3A,CLSTN2,APRT,GAS6,PHGDH,DNAH1,BZW2,ANKRD54,DCTPP1,C6orf48,RGS17,LDOC1L,VPS72,MCM5,ATIC,BANF1,TIMELESS,GREB1,MFAP2,CCDC88C,ALDH18A1,PPA1,NIPSNAP1,MSI2,APEX1,PSAT1,ARHGAP39,HOMER2,UTP15,BAZ2B,VCAN,BMP4,CNDP2,NR2F2,MACROD1,MMP16 |
| 6.297e-03 | -5.07 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | 178 | 35 | 17758 | 2279 |
PTP4A1,TTN,OXNAD1,PCNT,RBM33,ITPRIP,ST7L,PRKCA,TIGD1,FAM8A1,DDIT4,IQGAP2,COMMD9,SUCLG2,FHIT,SNX29,DIS3L2,EIF4E3,GPHN,TSPYL4,PTPRM,RAP1GAP2,ARRDC3,MEF2D,ENC1,TTC28,ST3GAL5,TMEM132B,ZDHHC11,GADD45A,MPP7,PPP3CC,DTD1,SMYD3,LPP |
| 6.310e-03 | -5.07 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | REACTOME pathways | R-HSA-6781827 | 77 | 19 | 8202 | 1117 |
USP7,GTF2H3,RFC4,RFC3,CUL4A,GTF2H2C,POLK,UBC,POLR2A,RPA1,ELL,COPS4,POLE2,COPS3,COPS5,GTF2H1,COPS7B,COPS6,PRPF19 |
| 6.317e-03 | -5.06 | PRPF8 (pre-mRNA processing factor 8) | protein interactions | 10594 | 145 | 32 | 16036 | 2270 |
SART1,CUL7,FN1,PRPF31,TCF3,PLRG1,SIRT7,GIGYF2,PIP4K2A,NEDD4,SNW1,BCAS2,MYC,SHMT2,RNF2,SRRM2,PABPC1,HNRNPM,TOP1,SRPK2,PRPF19,SF3A1,SIRT6,RANGAP1,PHF6,UBC,RPA1,DDX3X,RANBP2,MYBBP1A,HNRNPR,PRPF4 |
| 6.330e-03 | -5.06 | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | 197 | 38 | 17758 | 2279 |
MIF4GD,JUP,ATP6V1A,LPCAT3,BHLHE40,FOXP1,MAP2K3,ANXA10,SLC25A20,PHC2,FKBP1A,LPIN2,ANXA5,VAPB,ETF1,CNOT4,IFRD1,ANTXR2,AEBP2,SLC3A2,CMIP,TSN,HSPA5,TOR1AIP2,ZNFX1,PTK2,PITPNB,ISG15,ARIH2,SRCAP,DDX50,KPNA1,TNFRSF1A,MSH3,TRAF3,IFITM2,NFKBIB,PKIB |
| 6.347e-03 | -5.06 | fibula | COSMIC cancer mutations | fibula | 408 | 70 | 17775 | 2278 |
USP7,ABCA3,C16orf45,SBF2,STK33,RADIL,AARS,JAG1,CAMTA2,NAA35,DBN1,TNK2,KMT2D,SKAP2,ABCC4,LIMA1,EHMT1,MARCKSL1,GNL1,SERGEF,DHX57,OSBPL1A,BAZ1A,CC2D1B,ARL13B,ZNF436,TRMT2A,ABCC3,MDN1,NFRKB,ANKS1A,LAMA5,CEP170,UNC13D,BRAF,FN1,LARS2,PDE4B,EVPL,BZW2,SCAF1,NDRG4,GREB1,POLR1B,FBXL19,LPCAT1,ZNF675,TMC7,ZNF234,BDNF,KCNQ3,PDE4A,ADAMTSL3,EPS15L1,OBSCN,PDE3B,AGAP1,SMPDL3B,MFN2,EXOC6,KIDINS220,WDR35,LEMD3,FAT1,SPEN,MSH3,ATM,PGAM5,SORCS2,DDX10 |
| 6.353e-03 | -5.06 | DCTN1 (dynactin 1) | protein interactions | 1639 | 90 | 22 | 16036 | 2270 |
FLNC,DCTN3,FBXW4,APEX1,SEC24D,PAFAH1B1,ZNF512B,SF3A3,VIM,EIF2A,SAP30BP,MAP2K3,POP1,DST,FBXL5,DYNC1H1,BICD1,CC2D1B,DCTN4,DTNBP1,MAPT,CDC37 |
| 6.353e-03 | -5.06 | SMAD7 (SMAD family member 7) | protein interactions | 4092 | 90 | 22 | 16036 | 2270 |
ASH1L,STAMBP,SMAD7,ZNF107,TGFBR2,MAP2K3,NEDD4,TCF7L2,SMAD3,FKBP1A,KDM2A,UCHL5,MYC,COPS5,MKL2,ZEB1,RNF111,ATM,USP11,ZBTB11,PARD3,USP15 |
| 6.362e-03 | -5.06 | ANXA5 (annexin A5) | protein interactions | 308 | 44 | 13 | 16036 | 2270 |
UNC13D,TERF2IP,CUL7,SUPT4H1,IFNGR2,ACTG1,HARS,H2AFX,FUS,ISG15,ANXA1,TERF2,FDFT1 |
| 6.362e-03 | -5.06 | CIAPIN1 (cytokine induced apoptosis inhibitor 1) | protein interactions | 57019 | 44 | 13 | 16036 | 2270 |
DCTPP1,RNF40,EPRS,GARS,ATP6V1A,UCHL5,CUL2,HSPB8,XPNPEP1,MARS,AARS,NMD3,CIAPIN1 |
| 6.362e-03 | -5.06 | RBPJ (recombination signal binding protein for immunoglobulin kappa J region) | protein interactions | 3516 | 44 | 13 | 16036 | 2270 |
USP7,SNW1,NCOR2,SUFU,GADD45A,KDM5A,SPEN,MYC,MED27,SMARCA4,NCOR1,ZNF589,KDM1A |
| 6.362e-03 | -5.06 | SKI (SKI proto-oncogene) | protein interactions | 6497 | 44 | 13 | 16036 | 2270 |
SMAD3,SKIL,DYRK1B,SNW1,RB1CC1,PRDM16,HIPK2,EYA3,RNF111,NCOR1,PRMT5,MYB,SKI |
| 6.396e-03 | -5.05 | V$E47_01 | MSigDB lists | V$E47_01 | 242 | 45 | 17758 | 2279 |
ZNF706,RELL2,GNB3,CYLD,DLL4,MINK1,ID1,MYO7A,CACNA1H,HES6,FOXP1,CHD5,GIT2,WNT2B,STC2,CORO1A,TTC17,SERBP1,SPTAN1,FAM98A,FLNC,PPP1R9B,FGF9,KIRREL2,PPP1R21,KCNMA1,LGALS1,AKAP12,RANGAP1,KCNH2,PLCB1,SERGEF,HSD3B7,BTBD11,SPOP,EXOC6,NSD1,EIF4ENIF1,ARL4A,RBPJ,RUNX1,SORCS2,BRSK2,ZMAT3,ZNF532 |
| 6.426e-03 | -5.05 | methyltransferase complex | cellular component | GO:0034708 | 88 | 20 | 17570 | 2233 |
KAT8,METTL1,AEBP2,KMT2D,SETD1B,PRPF31,KMT2E,TAF1,KMT2C,MEN1,TRIM37,PELP1,CLNS1A,MGA,KANSL1,TAF4,SENP3,RNF2,PRMT5,KMT2A |
| 6.428e-03 | -5.05 | MASSARWEH_RESPONSE_TO_ESTRADIOL | MSigDB lists | MASSARWEH_RESPONSE_TO_ESTRADIOL | 59 | 15 | 17758 | 2279 |
IRS1,RBBP8,PMAIP1,LARGE,PSMG1,GREB1,SCARB1,APTX,SOX4,NRIP1,TMCO6,MAPT,SMPDL3B,FLNB,MYB |
| 6.428e-03 | -5.05 | MODULE_525 | MSigDB lists | MODULE_525 | 59 | 15 | 17758 | 2279 |
C1orf159,WDR75,INSIG1,MIOS,INTS7,PMAIP1,FMNL1,EXOC6B,DBF4,TRAK1,AEN,NOC3L,DDX49,STK10,NMD3 |
| 6.453e-03 | -5.04 | NAKAMURA_CANCER_MICROENVIRONMENT_DN | MSigDB lists | NAKAMURA_CANCER_MICROENVIRONMENT_DN | 43 | 12 | 17758 | 2279 |
CARS,RFC4,ASNS,SYNCRIP,PSAT1,SLC7A11,HOMER2,PSMG1,MARS,COTL1,TARS,TRIP13 |
| 6.504e-03 | -5.04 | CBS (cystathionine-beta-synthase) | protein interactions | 875 | 64 | 17 | 16036 | 2270 |
SKIV2L,CARS,VTA1,COL4A3BP,PSMA1,AP1B1,UBC,SEC31A,ASNS,IREB2,GPN1,LRSAM1,PDLIM5,SRP14,NMD3,RTFDC1,IPO4 |
| 6.525e-03 | -5.03 | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 677 | 109 | 17775 | 2278 |
SLC37A3,DMXL2,MYCBP2,ZNF76,THOC5,ACTG1,CNTNAP3,TMEM183A,NAT10,RIPK1,CSPP1,BCOR,HMOX2,DENND3,CIAPIN1,ZC3H13,DST,CCDC50,RPS6KL1,ZNF142,CHD2,GSTA4,BCAP29,POLR3B,MTHFD2L,SRRM2,ETV1,ZC3H3,FLNC,DPF3,KMT2D,OSBP2,ABCC4,GPCPD1,RFX2,ATXN1,LAMA2,EDEM2,SON,DSP,UBR4,BAZ1A,KPNA3,SMARCC1,LMBR1L,INTS9,FTSJ1,VPS13D,SCARB1,MAGI1,BRD9,LAMA5,SLC12A7,HERC2,CARS,TNIK,TMEM63C,BCKDK,BRAF,ZHX3,ITPRIP,RFX1,PAX2,ZNF280C,ATF7IP,ATG2B,DNAH1,NEDD4,MTUS1,RSPRY1,FAM50A,MCAM,PVRL3,ZNF710,ZCCHC7,MAP3K12,SAMD3,PKNOX1,HMGCR,FAM120B,KLRD1,TSHZ1,IFRD1,TSTA3,MYO10,OBSCN,CHCHD6,CCDC150,POLR3A,DAGLA,EPRS,RARS,PXDN,FAM135A,MYBBP1A,ALG5,ACOX1,FAT1,SNAP23,VPS37B,CSRNP1,EXOC4,MSH3,ATM,PFDN2,C12orf45,MIPOL1,KDM4C,IPO4 |
| 6.542e-03 | -5.03 | USP28 (ubiquitin specific peptidase 28) | protein interactions | 57646 | 49 | 14 | 16036 | 2270 |
USP7,TP53BP1,ZCCHC8,STAMBP,UCHL5,MYC,NSMCE2,RCHY1,USP20,JOSD1,STAM,KDM1A,UBC,USP15 |
| 6.542e-03 | -5.03 | TAF4 (TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa) | protein interactions | 6874 | 49 | 14 | 16036 | 2270 |
TAF2,TCF12,ANAPC1,TRRAP,CDC16,GTF2A1,ANAPC13,TAF1,TAF3,TAF4,TBPL1,TAF12,SOX6,TAF9B |
| 6.542e-03 | -5.03 | ABCF1 (ATP binding cassette subfamily F member 1) | protein interactions | 23 | 49 | 14 | 16036 | 2270 |
SUB1,RFC4,FN1,COPS5,FMNL1,CUL2,SIRT7,RNF2,YBX3,EIF2B3,FKBP3,HNRNPM,SPAG6,IGF2BP3 |
| 6.542e-03 | -5.03 | SP100 (SP100 nuclear antigen) | protein interactions | 6672 | 49 | 14 | 16036 | 2270 |
TERF2IP,RANBP2,USPL1,L3MBTL3,HIPK2,SUMO3,PUS1,AHCYL1,AGL,IGBP1,CASP8AP2,TERF2,TOM1L1,MYB |
| 6.544e-03 | -5.03 | RAD21 (RAD21 cohesin complex component) | protein interactions | 5885 | 244 | 49 | 16036 | 2270 |
CUL4A,EIF3C,ACTR3,SIRT7,H2AFJ,OLA1,SF3A3,CCDC7,CSTA,HNRNPA3,FLNB,WNT2B,CAD,SNW1,AMPD3,PDZD2,RPS16,MYC,PDS5B,RNF2,RAN,RPL22L1,TMPO,EVL,RFC3,STAG1,SIRT6,SKIV2L2,PSPC1,TOP3A,GNL1,BRCA1,HIST1H4J,MCM2,TMSB4X,UBC,RPA1,DDX3X,BRCA2,SYNCRIP,SSU72,TRAP1,CHD3,CDK9,NSMCE2,EIF2S1,CLU,YEATS2,ANAPC4 |
| 6.547e-03 | -5.03 | organelle inner membrane | cellular component | GO:0019866 | 515 | 85 | 17570 | 2233 |
CYP24A1,IMMP2L,NDUFA5,LETM1,SUCLG1,NDUFAF2,PDK4,MRPL10,NDUFB5,SLC25A21,SLC25A44,SLC9B2,COX10,COA1,MRPS30,NDUFB3,ABCA12,ATP5G2,LETM2,MRPS27,NDUFA6,MTHFD2L,TMEM120B,SLC25A23,MPST,TIMM50,TMPO,ACSL5,SFXN4,CPOX,FOXRED1,MGST1,MPC1,ATP5D,STOML2,SNCA,TIMM44,SMAD3,TAMM41,TIMM17A,MPV17,SLC25A11,FAHD1,UQCC2,SLC25A26,MTCH1,HERC2,AK2,HSD17B10,SLC25A12,OPA1,TIMM10,NDUFS7,SLC25A20,MRPS11,NDUFV1,PMPCA,SHMT2,ALDH18A1,MRPL21,COQ3,SLC25A1,NIPSNAP1,TIMM8B,BDNF,SIGMAR1,TMEM126A,BCS1L,MRPS10,EXOG,CPT1A,GUF1,CHCHD6,C19orf70,MRPL36,ETFDH,TRAP1,LEMD3,COQ9,SURF1,SLC25A19,NDUFAF5,GPAM,NDUFS5,UQCC1 |
| 6.550e-03 | -5.03 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | protein interactions | 11338 | 151 | 33 | 16036 | 2270 |
SART1,CUL7,ZCCHC8,RBFOX2,KHDRBS1,PLRG1,SIRT7,PHGDH,GIGYF2,NOP56,SRSF2,BCAS2,RNF2,HNRNPM,TERF2,TOP1,SRPK2,PRPF19,SCAF11,SMARCAD1,PSPC1,PSMA1,ATXN1,RANGAP1,SAP30BP,POLR2A,DYNC1H1,HLA-DMA,DDX3X,SMAD3,SYNCRIP,HNRNPR,COPS5 |
| 6.551e-03 | -5.03 | protein sumoylation | biological process | GO:0016925 | 92 | 21 | 16441 | 2138 |
HERC2,STAG1,XPC,SUMO3,SCMH1,NUP43,BRCA1,NUP160,NUP214,RING1,POM121,RPA1,PHC2,RANBP2,NUP133,NSMCE1,NSMCE2,RNF2,XRCC4,BMI1,SEH1L |
| 6.591e-03 | -5.02 | ARPC2 (actin related protein 2/3 complex subunit 2) | protein interactions | 10109 | 59 | 16 | 16036 | 2270 |
METTL1,ARHGAP17,CUL7,ACTR3,RANGAP1,MTR,SH3GL1,RPA1,ARPC3,TOM1L1,TPD52L2,TNPO3,ANP32B,PUS1,ACTR3B,PRKACB |
| 6.618e-03 | -5.02 | Cdc73/Paf1 complex | cellular component | GO:0016593 | 7 | 4 | 17570 | 2233 |
PAF1,CTR9,WDR61,CDC73 |
| 6.618e-03 | -5.02 | hemidesmosome | cellular component | GO:0030056 | 7 | 4 | 17570 | 2233 |
DST,COL17A1,ITGB4,JUP |
| 6.628e-03 | -5.02 | skin-scalp-malignant_melanoma-desmoplastic | COSMIC cancer mutations | skin-scalp-malignant_melanoma-desmoplastic | 33 | 10 | 17775 | 2278 |
BRCA2,BRAF,CYLD,NRAS,SUFU,NF1,ATRX,SMARCA4,ATM,ARID1A |
| 6.647e-03 | -5.01 | WW_DOMAIN_2 | prosite domains | PS50020 | 49 | 13 | 11866 | 1504 |
CEP164,PRPF40B,APBB3,SETD2,ARHGAP39,WAC,PQBP1,WWC1,ARHGAP12,MAGI1,ARHGAP27,NEDD4,IQGAP2 |
| 6.650e-03 | -5.01 | TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING | MSigDB lists | TRANSLATION_FACTOR_ACTIVITY_NUCLEIC_ACID_BINDING | 38 | 11 | 17758 | 2279 |
GTF2H3,EIF2S2,EIF3C,EIF3J,COPS5,EIF4A2,EIF2S1,EIF2A,EIF2B3,ABCF1,PABPC1 |
| 6.650e-03 | -5.01 | ACTR2 (ARP2 actin-related protein 2 homolog (yeast)) | protein interactions | 10097 | 85 | 21 | 16036 | 2270 |
METTL1,CUL7,FN1,ACTR3,SIRT7,RANGAP1,UBC,SH3GL1,RPA1,ARPC3,TOM1L1,IQGAP2,TPD52L2,P3H1,ALAD,SURF2,CORO1A,ANP32B,ACTR3B,BAG1,PRKACB |
| 6.650e-03 | -5.01 | SERPINH1 (serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)) | protein interactions | 871 | 85 | 21 | 16036 | 2270 |
CUL7,TRIP6,PPARG,TCF3,SIRT7,HSPA5,TPM4,LGALS1,METTL23,VIM,STAM,TIMM44,UBTF,COL26A1,BRCA2,TOM1L2,MYC,SEC24C,CDK9,ZEB1,AHCYL1 |
| 6.650e-03 | -5.01 | CLNS1A (chloride channel, nucleotide-sensitive, 1A) | protein interactions | 1207 | 85 | 21 | 16036 | 2270 |
SEC24A,FN1,TRIP6,RBFOX2,UBXN1,HSPA5,EIF4A2,LGALS1,CSNK2A1,DDAH2,TPD52L2,PDLIM1,SEC24C,ATIC,PFDN2,PRMT5,LSM10,PPA1,AGO3,LPP,RPS6KB2 |
| 6.652e-03 | -5.01 | RNA_BINDING | MSigDB lists | RNA_BINDING | 249 | 46 | 17758 | 2279 |
CARS,SARS,AUH,RBFOX2,KHDRBS1,RPS29,SF3A3,FARS2,ZFP36L1,IGF2BP2,ZNF346,NOL3,PARN,AARS,MBNL1,PABPC4,NOP56,IGF2BP3,ZNF239,EIF2S2,BCAS2,PTRF,ETF1,CELF1,FBL,PABPC1,SERBP1,SCAF11,EXOSC2,RNMT,NOL6,PSMA1,ATXN1,EIF2A,APTX,OASL,DKC1,GEMIN5,IREB2,SYNCRIP,RPL28,HNRNPR,PURB,ZRANB2,TROVE2,SRP14 |
| 6.652e-03 | -5.01 | V$GABP_B | MSigDB lists | V$GABP_B | 249 | 46 | 17758 | 2279 |
SCAMP3,WDR74,NF1,ANKRD17,UBXN1,SSR4,SLC30A7,FAM192A,RSPRY1,SPG21,BANF1,AP1M1,HARS2,UPF2,CELF1,AGL,CSGALNACT2,DIS3L2,RABEPK,VPS13B,SF3A1,USE1,NRAS,RAB7A,PPP1R21,IDH3G,SUPT5H,RHOT2,STK10,EIF3H,VPS53,PHF6,SEC31A,DNTTIP1,TMCO1,ELP2,PER1,CDK9,CCDC85B,ATM,TRMT2A,GALNT10,BRCC3,XRCC4,DDIT3,LRRC41 |
| 6.655e-03 | -5.01 | CSNK2A2 (casein kinase 2, alpha prime polypeptide) | protein interactions | 1459 | 203 | 42 | 16036 | 2270 |
HMGA2,NIFK,XPC,PLRG1,SIRT7,CSNK2A1,CCNL2,RSRC1,PIP4K2A,KDM1A,RING1,BCAS2,MYC,HIRIP3,RNF111,RNF2,KMT2A,TERF2,TOP1,PRPF19,CDC37,PCGF3,FGF2,EIF3J,ZC3H18,CAV1,PNN,SUPT5H,SAP30BP,FKBP3,EIF3H,TCF7L2,UBC,SNCA,RPA1,PAF1,POP1,GTF2A1,STX1A,NRP1,NOLC1,C18orf25 |
| 6.663e-03 | -5.01 | DNA-dependent ATPase activity | molecular function | GO:0008094 | 80 | 19 | 16491 | 2164 |
RFC4,GTF2H3,RFC3,MCM6,ATRX,SMARCA4,RAD54B,ANXA1,DDX3X,ASCC3,RAD18,CHD3,XRCC2,RAD51B,MSH3,GTF2H1,CHD2,MSH4,TOP1 |
| 6.684e-03 | -5.01 | ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE | MSigDB lists | ESTABLISHMENT_AND_OR_MAINTENANCE_OF_CHROMATIN_ARCHITECTURE | 76 | 18 | 17758 | 2279 |
KAT8,HMGA2,EHMT1,HDAC8,SIRT2,ARID1A,RSF1,RPS6KA5,CHAF1A,NSD1,SUPT4H1,SUV39H2,SMARCC1,SET,HIRIP3,MAP3K12,CARM1,KAT6A |
| 6.693e-03 | -5.01 | PETRETTO_CARDIAC_HYPERTROPHY | MSigDB lists | PETRETTO_CARDIAC_HYPERTROPHY | 33 | 10 | 17758 | 2279 |
DDX3X,COL5A2,FN1,CRIM1,SNAP23,ARID5B,RTN4,ST3GAL6,CD44,ANXA1 |
| 6.702e-03 | -5.01 | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | 185 | 36 | 17758 | 2279 |
OLFM2,LRRC28,ARL15,KLC4,TATDN3,LAGE3,MED13L,TMEM104,SSBP2,LYRM2,RTN1,MLX,RABGAP1L,HARS2,POLE3,LYRM5,PPM1K,RPS6KB2,MYB,KDM5B,ZC4H2,SLCO6A1,TOR1AIP2,MEN1,AGAP1,PLCXD2,CCDC28B,TAF9B,ZNF266,COPS5,METTL6,GREB1L,FNBP1L,DCAF5,DOCK6,SLC16A10 |
| 6.702e-03 | -5.01 | GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_DN | 185 | 36 | 17758 | 2279 |
MPI,INSIG2,NF1,LRRC28,MRI1,HES6,SSBP2,GBF1,BCAP29,NRIP1,AVEN,SNAPC5,MBTPS2,TERF2,SPTAN1,ANTXR2,CHD9,ELOVL6,ANKMY2,GNG7,TMEM123,ZNF467,DENND4A,EHBP1,PEAK1,NSD1,TASP1,DAGLB,HIPK2,IRAK2,CSRNP1,INTS9,SLC4A7,DTD1,TAF12,TMEM158 |
| 6.702e-03 | -5.01 | YAGI_AML_FAB_MARKERS | MSigDB lists | YAGI_AML_FAB_MARKERS | 185 | 36 | 17758 | 2279 |
LARS2,PRSS3,PBX1,CSTA,GIT2,MAN1A1,TOM1L1,S100A10,CTR9,ANXA5,SERPINH1,AHCYL1,ITGAX,VCL,SLC25A1,FADS1,RFC4,DEAF1,RFC3,ELOVL6,ARID5B,LGALS1,ATXN1,PSMG1,CAV1,PNN,CYB5B,ZNF91,CXADR,SLC7A1,AHNAK,TBPL1,SQLE,PTPN4,TPM1,LAMA5 |
| 6.794e-03 | -4.99 | V$CREB_Q2_01 | MSigDB lists | V$CREB_Q2_01 | 217 | 41 | 17758 | 2279 |
SPRED2,CYLD,BRAF,ID1,EGR1,NF1,PAFAH1B1,DDX19A,RPS29,PPHLN1,PPP2R2A,RCAN1,MCAM,SREBF2,THADA,CACNB2,GLYR1,IKBKB,RELB,JOSD1,CTC1,SNAPC5,DDX28,VPS37A,LDHA,SULT4A1,TPM4,MRRF,GNL1,SNAP25,MARCH6,MBNL2,SAP30BP,NCDN,TAF2,DNTTIP1,SPAG9,GTF2A1,SYNCRIP,ADNP,VPS37B |
| 6.809e-03 | -4.99 | phospholipid metabolic process | biological process | GO:0006644 | 311 | 56 | 16441 | 2138 |
SERINC5,PIGM,PIGN,MVK,PRDX6,PAFAH1B1,LPCAT2,GPAT3,PIGH,PIK3R4,PLA2G12A,DPM3,LPCAT3,IP6K2,ABHD6,SYNJ1,LCLAT1,INPP1,PIP4K2A,LPIN1,IDI1,PI4KB,LPIN2,PIGG,SYNJ2,CPNE7,PNPLA3,MGLL,LPCAT1,LYST,FDFT1,FADS1,FGF2,PI4KAP2,AGPAT4,GPCPD1,PITPNB,PLCB1,NAPEPLD,PIK3CB,SMPDL3B,VAC14,SNCA,TAMM41,ALG5,SERINC1,GATA6,PEMT,ABHD3,FDPS,SRD5A3,ATM,GPAM,BPNT1,MTMR1,SMG1 |
| 6.824e-03 | -4.99 | RUVBL2 (RuvB-like AAA ATPase 2) | protein interactions | 10856 | 215 | 44 | 16036 | 2270 |
USP7,EP400,CUL7,FN1,ACTG1,MLH1,TTI1,CAD,SHC1,NEK6,UCHL5,VPS72,CFDP1,MYC,ARHGAP1,RNF2,DYNC2H1,FBL,SRRM2,FDFT1,RPS6KB2,RFC4,SIRT6,SMARCAD1,HSPA5,LIG4,BRCA1,DKC1,NOP58,POLR2A,UBC,RPA1,DYNC1H1,SRCAP,EHMT2,HIF1A,CDK9,RIOK3,NFRKB,BMI1,C12orf45,IPO4,AGO3,SMG1 |
| 6.828e-03 | -4.99 | Global Genome Nucleotide Excision Repair (GG-NER) | REACTOME pathways | R-HSA-5696399 | 83 | 20 | 8202 | 1117 |
GTF2H3,RFC4,RFC3,CUL4A,XPC,GTF2H2C,POLK,PARP2,SUMO3,UBC,RPA1,COPS4,POLE2,COPS3,COPS5,RNF111,GTF2H1,COPS7B,NFRKB,COPS6 |
| 6.859e-03 | -4.98 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_AND_PAX3 | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_AND_PAX3 | 7 | 4 | 17758 | 2279 |
JAG1,FN1,PSTPIP2,NR2F1 |
| 6.859e-03 | -4.98 | LIU_CMYB_TARGETS_DN | MSigDB lists | LIU_CMYB_TARGETS_DN | 7 | 4 | 17758 | 2279 |
SOBP,ATP6V1A,CYB5B,SRRM2 |
| 6.861e-03 | -4.98 | neural tube formation | biological process | GO:0001841 | 104 | 23 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,LUZP1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SOX4,TCTN1,SKI,HIF1A,BMP4,APAF1,PRKACB,STK4,MTHFD1 |
| 6.876e-03 | -4.98 | visual learning | biological process | GO:0008542 | 48 | 13 | 16441 | 2138 |
ABL2,DEAF1,BRAF,SYNGAP1,NF1,HIF1A,NDRG4,ATXN1,NLGN3,KMT2A,PDE8B,HMGCR,HRH1 |
| 6.886e-03 | -4.98 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 179 | 35 | 17758 | 2279 |
ASCC1,MAP3K13,NBEAL1,PRKCH,FAM50A,CFDP1,DTNBP1,WDR60,CLDND1,LPCAT1,FUT11,SF3A1,SAP30,GTF2H3,VPS37A,SLC3A2,KIAA1143,DDX41,PDK1,LSM12,GNL1,ARL5B,ABCF1,TJAP1,GNAI1,ZFP62,UBAP2,NSMCE2,RIOK3,XPNPEP1,C7orf50,RBPJ,NFKBIB,CATSPERG,DDIT3 |
| 6.886e-03 | -4.98 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN | 179 | 35 | 17758 | 2279 |
SRM,PIGM,AK2,STXBP6,MED18,PPIL1,ZNF709,YARS2,ZNF239,POLR3D,ARHGAP18,ARMC6,LARP4B,PRADC1,MYB,ZNF234,ALG6,CRIM1,CDK4,SCFD2,PSMG1,ATXN1,PEAK1,RBM28,SLC39A14,SLC7A1,POP1,RBBP8,PAM,FNTB,MED20,TSEN2,FAHD1,METTL2B,PTPN14 |
| 6.888e-03 | -4.98 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 198 | 38 | 17758 | 2279 |
CARS,ITFG1,TCF3,RCHY1,CSNK2A1,SPATS2,INPP1,PDCD5,DECR1,UBE3A,SLC39A7,PDS5B,C16orf58,ALDH18A1,CCDC88C,AVEN,SNAPC5,TOP1,SEC24A,WDR61,C11orf80,R3HDM1,YIPF3,PPIP5K2,ATP5D,RARS,EPRS,YIPF2,SERF2,KPNA3,GADD45A,TIMM17A,POLR3E,SURF1,HMBS,COPS6,EIF2B3,TXN2 |
| 6.900e-03 | -4.98 | MORF_DEK | MSigDB lists | MORF_DEK | 256 | 47 | 17758 | 2279 |
PRPF31,KHDRBS1,RTN4,XPO7,POM121,TERF2IP,NDUFV1,SREBF2,BANF1,ETF1,SSBP1,RAN,POLE3,ANP32B,FBL,PRPS1,HNRNPM,TOP1,KDM3B,RFC4,IFRD1,EIF4A2,LDHA,PCMT1,R3HDM1,SUMO3,TMEM123,MCM2,SON,SERP1,DDX49,POLR2A,EIF3H,CLNS1A,UBE2E1,STOML2,RPA1,HPRT1,SYNCRIP,HNRNPR,COPS5,SET,ACP1,GPN1,COPS6,XPO6,SRP14 |
| 6.902e-03 | -4.98 | RNA Polymerase III Chain Elongation | REACTOME pathways | R-HSA-73780 | 18 | 7 | 8202 | 1117 |
CRCP,POLR3D,POLR3B,POLR1C,POLR3A,POLR3E,POLR3G |
| 6.905e-03 | -4.98 | human chr1q32.3 | chromosome location | human chr1q32.3 | 24 | 7 | 26250 | 2590 |
NAV1,VASH2,FLVCR1,INTS7,TMEM206,BATF3,TATDN3 |
| 6.918e-03 | -4.97 | POLR2C (polymerase (RNA) II (DNA directed) polypeptide C, 33kDa) | protein interactions | 5432 | 96 | 23 | 16036 | 2270 |
ATF4,FN1,SUPT6H,MED27,TCEB3,ATF7IP,BRCA1,NELFA,SUPT5H,UBC,NEDD4,POLR2A,POLR3G,HNRNPR,INTS5,COPS5,STC2,ZNF326,GTF2H1,INTS12,CTR9,POLR1C,PRMT5 |
| 6.928e-03 | -4.97 | SMTTTTGT_UNKNOWN | MSigDB lists | SMTTTTGT_UNKNOWN | 382 | 66 | 17758 | 2279 |
PTP4A1,ZNF706,TRERF1,NF1,ATRX,RNF43,PABPC4,NRF1,SRSF2,KDM2A,GLYR1,SLC38A2,MMP14,CHD2,ETV1,ZMYM2,IPO11,HN1,SRPK2,SOBP,ZCCHC14,DPF3,GPM6A,SLC3A2,AKAP8L,SLC38A1,NR6A1,SFSWAP,PREX1,POU2F1,SATB2,RAB10,RAD54B,C1orf122,YTHDF2,DDX3X,SLC7A1,EPN2,SLC30A3,LUC7L3,ZNF436,FKBP5,ZBTB11,MID1,JUP,CLK1,ID2,BTBD9,ZFP36L1,IP6K2,FOXP1,CSNK1A1,MBNL1,MTUS1,CHN1,PTGS1,NLGN3,IL11RA,USP49,MYO10,FOXN3,ZMYM5,SYCP2L,SET,ITGB4,KIF1B |
| 6.931e-03 | -4.97 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | MSigDB lists | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | 54 | 14 | 17758 | 2279 |
GTF2H3,ELL,SUPT4H1,GTF2A1,TAF1,CCNT1,CDK9,TAF4,TCEB3,GTF2H1,NCBP2,TAF12,SUPT5H,POLR2A |
| 6.931e-03 | -4.97 | PID_TAP63_PATHWAY | MSigDB lists | PID_TAP63_PATHWAY | 54 | 14 | 17758 | 2279 |
DST,VDR,ABL1,JAG1,GADD45A,PMAIP1,MFGE8,IKBKB,SMARCD3,AEN,EVPL,ITGB4,OGG1,PERP |
| 6.936e-03 | -4.97 | DOUGLAS_BMI1_TARGETS_DN | MSigDB lists | DOUGLAS_BMI1_TARGETS_DN | 302 | 54 | 17758 | 2279 |
KLHL24,PTCD2,OXNAD1,MIF4GD,INSIG2,ATP6V1A,KLHL18,NECAP1,TIGD1,HMOX2,BIRC2,DDX60L,PAG1,RNF141,ANAPC1,SLC7A11,NSRP1,CBR4,FGGY,C16orf58,ATP6V0D1,SOX6,CTC1,GPM6A,RBCK1,COL5A2,ZFYVE1,KATNAL1,MED16,CCNDBP1,ARL5B,FOXRED1,PIK3CB,TMEM175,NEU1,ECH1,APBB3,ATAD5,LRP1B,IREB2,SERINC1,INSIG1,ARNTL,MPV17,RWDD2B,CLU,APAF1,BMI1,TROVE2,ANKS1A,C18orf25,COG5,NIT1,LPP |
| 6.940e-03 | -4.97 | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | MSigDB lists | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | 409 | 70 | 17758 | 2279 |
CYLD,ID1,PDK4,FAM13A,ASNS,PMAIP1,RABGAP1L,ME1,MET,YARS,TMPO,ACSL5,FLNC,SOBP,ABCC4,KRT7,SLC38A1,PPARG,ANK2,TFPI,AKAP13,SOX4,DSP,WARS,GLS,SLC7A1,KLF4,G6PD,SYNPO,AP2S1,KLHL24,AOC3,FOXO1,EGR1,FN1,CLK1,RHOBTB1,BHLHE40,TGFB2,RPS6KA5,SLC1A1,MAN1A1,MTUS1,NAMPT,EIF2S2,SLC7A11,MYC,STC2,SHMT2,CD44,NRIP1,HNRNPM,PSAT1,ADAMTSL3,MYO10,FGF2,TPM4,RAP1GDS1,MARS,IL6R,GPNMB,OASL,KLF6,ANGPTL4,DKK1,TRIB3,LRP1B,PPP1R12B,PDLIM5,SLC43A1 |
| 6.951e-03 | -4.97 | HOOI_ST7_TARGETS_UP | MSigDB lists | HOOI_ST7_TARGETS_UP | 82 | 19 | 17758 | 2279 |
ARHGAP26,FLNC,TRIP6,ANKRD33B,COL4A3BP,SLC35G1,MED13L,NLN,ADAMTS6,SYT1,NAPEPLD,AHCYL2,ASNS,ARHGAP18,GPR87,TNPO3,TBL1X,MAP3K14,PEG10 |
| 6.961e-03 | -4.97 | transcription corepressor activity | molecular function | GO:0003714 | 219 | 42 | 16491 | 2164 |
NCOR2,ZHX3,RBFOX2,SMARCA4,ATF7IP,BCOR,TRIM22,BHLHE40,SKI,SNW1,SRSF2,HR,JAZF1,RELB,ZEB1,ZNF85,YBX3,PRMT5,NRIP1,CASP8AP2,SAP30,AEBP2,APEX1,KDM5B,SIRT6,BATF3,TAF9B,RERE,SKIL,TRIB3,NSD1,MYBBP1A,RBBP8,SUFU,HIPK2,SPEN,NCOR1,TBL1X,NR2F2,BEND6,N4BP2L2,DDIT3 |
| 7.012e-03 | -4.96 | COLLIS_PRKDC_SUBSTRATES | MSigDB lists | COLLIS_PRKDC_SUBSTRATES | 19 | 7 | 17758 | 2279 |
POU2F1,ABL1,XRCC4,MYC,POLR2A,RPA1,H2AFX |
| 7.012e-03 | -4.96 | GAJATE_RESPONSE_TO_TRABECTEDIN_DN | MSigDB lists | GAJATE_RESPONSE_TO_TRABECTEDIN_DN | 19 | 7 | 17758 | 2279 |
FARS2,GMDS,STX8,TRIM16,STAG1,DDX10,MCM5 |
| 7.012e-03 | -4.96 | RUAN_RESPONSE_TO_TROGLITAZONE_DN | MSigDB lists | RUAN_RESPONSE_TO_TROGLITAZONE_DN | 19 | 7 | 17758 | 2279 |
AOC3,AK2,NRIP1,PPARG,PEMT,IDH3G,HK2 |
| 7.034e-03 | -4.96 | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | MSigDB lists | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | 416 | 71 | 17758 | 2279 |
VMA21,USP7,BCCIP,PTP4A1,ASH1L,PRDX6,WDR74,TMEM109,GYG1,ZNF44,CUTC,PABPC4,PAIP2,TERF2IP,BRE,SPG21,DNAJB6,GSTA4,AHCYL1,VCL,NFIA,ATXN1,VIM,AKAP13,ODC1,MAT2A,CLNS1A,YTHDF2,ARPC3,SPOP,PLIN2,SLC39A14,LSM14A,COPS5,HIPK2,PAM,HSPB8,LARGE,COPS6,TPM1,MAPT,VIPR1,SEPHS2,C9orf78,ANKRD17,SLC25A12,POM121,MTUS1,SUB1,SNW1,UBE3A,EIF2S2,ANXA7,COPS3,VAPB,CELF1,MSI2,IFNGR2,TMEM126A,ADSL,MRPS10,MAPK1IP1L,PIK3CB,HERPUD1,OXSR1,SET,HK2,SVIL,PTP4A2,ZAK,SRP14 |
| 7.068e-03 | -4.95 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | 173 | 34 | 17758 | 2279 |
VIPR1,TTN,RBM33,ITPRIP,FOSL2,FAM8A1,ABL2,FHIT,KIAA0922,AMOT,SNX29,IL11RA,RREB1,TSPYL4,UPP1,PTPRM,ARRDC3,ST6GALNAC3,MEF2D,ENC1,SOX4,TTC28,ST3GAL5,PLCXD2,ZFAND3,FBXL5,NAP1L5,ARHGAP21,ZDHHC11,GADD45A,HELZ,BBIP1,PPP3CC,KAT6A |
| 7.075e-03 | -4.95 | BACH1 (BTB and CNC homology 1, basic leucine zipper transcription factor 1) | protein interactions | 571 | 35 | 11 | 16036 | 2270 |
SMAD3,RBCK1,BRCA2,PALB2,SHMT2,NCOR1,MLH1,BRCA1,BRCC3,CSNK1A1,DDIT3 |
| 7.080e-03 | -4.95 | HATPase_c | smart domains | SM00387 | 18 | 7 | 9131 | 1249 |
BCKDK,PMS1,MLH1,PDK1,TRAP1,PDK4,MORC2 |
| 7.095e-03 | -4.95 | ACTTTAT,MIR-142-5P | MSigDB lists | ACTTTAT,MIR-142-5P | 276 | 50 | 17758 | 2279 |
TCF12,SSH2,CUL4A,CELSR1,ARID2,WDR26,RSF1,HLTF,TGFBR2,SYNJ1,RPS6KA5,IGF2BP3,RTN1,SACS,UBR1,MBD2,PDS5B,ETV1,MGLL,HN1,DDHD1,ZCCHC14,PCGF3,CHD9,EIF4E3,STAG1,CMIP,BAZ2A,SETD2,JMJD1C,ZNF512B,RNH1,MCL1,MARCH6,SON,USP46,HERPUD1,ZFAND3,APBB3,RBBP8,LRP1B,HNRNPH3,SPEN,CUL2,PTPN4,NRP1,SPOCK2,NUDT22,ATXN7L2,TRIM36 |
| 7.099e-03 | -4.95 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP | 192 | 37 | 17758 | 2279 |
SHQ1,CCDC58,TTC27,ALG8,ISG20L2,IKBKAP,BZW2,RIOK2,CD96,ASAP1,DHX33,MCM5,GTF2H1,PRMT3,WDR61,SKIV2L2,TBRG4,FKBP3,UBE2E1,PLCXD2,SLC23A2,DDX3X,EXO1,POP1,TSR1,INSIG1,ELP2,ADNP,FAM206A,GPN1,SLC4A7,AEN,SLC16A1,NRP1,ADK,GPATCH4,USP15 |
| 7.099e-03 | -4.95 | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP | 192 | 37 | 17758 | 2279 |
TNIK,LRRC28,C16orf52,SBF2,ISG20L2,NUP160,UBTD2,PRKCE,ASAP1,INTS7,RABGAP1L,LPIN2,KDELC1,TTPAL,SIK3,PTBP2,FOXN3,SMARCAD1,HAUS6,GPCPD1,WDHD1,FKBP3,MAT2A,PLCXD2,BTBD11,PWP1,ATAD5,LSM14A,TP53BP1,LRRC40,ZNF436,SETD6,BLMH,MID1,GPATCH4,PKIB,TNRC6A |
| 7.099e-03 | -4.95 | CELL_CYCLE_PROCESS | MSigDB lists | CELL_CYCLE_PROCESS | 192 | 37 | 17758 | 2279 |
DCTN3,TTN,CUL4A,TAF1,PAFAH1B1,KHDRBS1,DBF4,TUBE1,MAD2L2,ABL1,NEK6,TRIAP1,XRCC2,ANAPC11,ANAPC10,PDS5B,TIMELESS,MSH4,RAN,PRMT5,CDK6,KRT7,CDK4,FOXN3,POLA1,KIF15,TOP3A,TBRG4,RAD54B,CDC16,BRCA2,CUL2,PAM,RAD51B,ATM,NOLC1,ANAPC4 |
| 7.107e-03 | -4.95 | WD_REPEATS_1 | prosite domains | PS00678 | 169 | 33 | 11866 | 1504 |
GNB3,PAFAH1B1,PLRG1,PIK3R4,WDR37,NUP43,CORO6,DENND3,NLE1,AMBRA1,PEX7,PAK1IP1,CORO1A,LYST,PRPF19,WDR36,WDR61,WDFY3,TLE3,WDR18,UTP15,WDHD1,PWP1,GEMIN5,WDR5B,HERC1,WDR7,TSSC1,PRPF4,APAF1,TBL1X,BRWD3,CORO2B |
| 7.108e-03 | -4.95 | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | MSigDB lists | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | 224 | 42 | 17758 | 2279 |
THOC5,AK2,XPC,PRPF31,SLC48A1,RBFOX2,TFIP11,MYH9,SPATS2,KDM1A,SFI1,SMARCB1,PHC2,CEP290,LRP2BP,SOCS6,JOSD1,YARS,SRRM2,LYPLA2,MPST,SF3A1,SCAF11,RANBP6,ATF4,TFCP2,HAUS6,RAP1B,SUMO3,MAK16,YTHDF2,VDR,LMBR1L,LEMD3,RRAGA,INTS9,TAF12,TXN2,PDSS2,SGSM3,ZBTB24,GALE |
| 7.142e-03 | -4.94 | glycosyl compound metabolic process | biological process | GO:1901657 | 338 | 60 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,MRI1,NDUFB5,OLA1,APRT,CHCHD10,NT5C3A,COX10,HSPA1A,NDUFS7,AHCYL2,NDUFB3,CAD,AMPD3,NDUFV1,ENTPD5,ATP5G2,CBR4,ATIC,MYH3,PPCDC,NT5C,CMPK1,NDUFA6,AHCYL1,FXN,NT5M,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,PPAT,UPP1,SULT4A1,LDHA,DLG4,ATP6V0A1,ADSL,IMPDH2,MAT2A,ATP5D,STOML2,SNCA,HSPA1B,HPRT1,NME7,COQ9,PEMT,SURF1,HK2,UMPS,NDUFS5,BPNT1,MACROD1,ADK |
| 7.154e-03 | -4.94 | ZHU_CMV_24_HR_DN | MSigDB lists | ZHU_CMV_24_HR_DN | 88 | 20 | 17758 | 2279 |
LAMA4,COL5A2,LAMC1,ACTG1,XPC,PAFAH1B1,TPM4,DDR2,ID2,ANXA1,PYCR1,CHN1,ABL1,VCAN,CFD,TNFRSF1A,C7orf50,RUNX1,TPM1,PABPC1 |
| 7.197e-03 | -4.93 | negative regulation of tyrosine phosphorylation of STAT protein | biological process | GO:0042532 | 7 | 4 | 16441 | 2138 |
PTPN2,CAV1,SOCS1,PIBF1 |
| 7.197e-03 | -4.93 | AMP biosynthetic process | biological process | GO:0006167 | 7 | 4 | 16441 | 2138 |
ADSL,APRT,ADK,PRPS1 |
| 7.197e-03 | -4.93 | snoRNA processing | biological process | GO:0043144 | 7 | 4 | 16441 | 2138 |
EXOSC2,EXOSC4,FBL,DKC1 |
| 7.197e-03 | -4.93 | snoRNA 3'-end processing | biological process | GO:0031126 | 7 | 4 | 16441 | 2138 |
EXOSC2,EXOSC4,FBL,DKC1 |
| 7.197e-03 | -4.93 | snRNA transcription from RNA polymerase II promoter | biological process | GO:0042795 | 7 | 4 | 16441 | 2138 |
ELL,ICE2,ZC3H8,SNAPC4 |
| 7.217e-03 | -4.93 | ANP32E (acidic nuclear phosphoprotein 32 family member E) | protein interactions | 81611 | 26 | 9 | 16036 | 2270 |
SARS,UCHL5,VPS72,ATG7,RDX,RNASEH2B,AHCYL1,PARD3,AHCYL2 |
| 7.217e-03 | -4.93 | GLTSCR2 (glioma tumor suppressor candidate region gene 2) | protein interactions | 29997 | 26 | 9 | 16036 | 2270 |
MPHOSPH10,SLX4,SIRT7,PSMA1,UPF2,EIF5B,ZC3H3,UTP4,PUM3 |
| 7.217e-03 | -4.93 | DNMBP (dynamin binding protein) | protein interactions | 23268 | 26 | 9 | 16036 | 2270 |
DBN1,ARHGAP17,DNM3,EVL,DNMBP,TUBA1A,KHDRBS1,ENAH,HSPA1B |
| 7.223e-03 | -4.93 | BRUINS_UVC_RESPONSE_EARLY_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_EARLY_LATE | 296 | 53 | 17758 | 2279 |
PTCD2,TTN,INSIG2,PHF3,ZCCHC8,UBN1,ATRX,C16orf95,EVPL,KDM1A,TOM1L1,PTPN2,ASAP1,APLF,DHX33,ATG3,BANF1,WAC,ALKBH8,ANKRD11,RNF111,PRICKLE2,SHMT2,CHD2,CCDC124,HCFC2,SRRM2,LPCAT1,CASP8AP2,C12orf4,ULBP1,DDHD1,IFRD1,ZCCHC14,GARS,MTIF2,GPCPD1,FRA10AC1,PTPN12,ARID1A,CHCHD6,PIK3CB,STK10,C19orf70,ZBTB25,EXO1,AHNAK,KPNA3,RAD18,SNAP23,VPS37B,SNX24,MACROD1 |
| 7.226e-03 | -4.93 | non-recombinational repair | biological process | GO:0000726 | 70 | 17 | 16441 | 2138 |
HERC2,POLA1,LIG4,BRCA1,HIST1H4J,MLH1,RBBP8,SLX4,BRE,KDM2A,TP53BP1,NSMCE2,H2AFX,ATM,BRCC3,XRCC4,PRPF19 |
| 7.247e-03 | -4.93 | MORF_ESR1 | MSigDB lists | MORF_ESR1 | 167 | 33 | 17758 | 2279 |
EP400,NF1,ATRX,SLC2A1,NFX1,KLHL18,BARX2,TTI1,PSMF1,MGA,TBC1D22A,MYC,NCKIPSD,CEP135,ZNF710,CASP10,RPS6KB2,KAT8,CHD9,MSX1,SULT4A1,KIAA0586,BRCA1,ERC1,PIK3CB,TAF2,HTR7,RBBP8,SLC30A3,MSH3,FNTB,RUNX1,SMG1 |
| 7.269e-03 | -4.92 | cellular amide metabolic process | biological process | GO:0043603 | 670 | 109 | 16441 | 2138 |
GGT1,IMMP2L,EIF3C,RARS2,AARS2,MRPL10,RPS29,CERS5,ST3GAL6,AARS,PABPC4,DENR,MRPS30,CAD,SRPRB,FARSA,MMP7,RPS16,ASNS,MRPS27,PPCDC,GSTA4,ETF1,YARS,MTHFD2L,HTRA2,NARS2,GDAP1,EIF4E3,GARS,NARS,HARS,EIF3J,ALDH1L2,MTIF2,COL4A3BP,MRRF,NLN,MTHFD1L,ST3GAL5,EIF3H,MGST1,WARS,DDX3X,HLCS,EEFSEC,COPS5,G6PD,BDH2,FTSJ1,PAM,XPNPEP1,EIF2B3,CARS,SARS,LARS2,AGO2,FARS2,PCSK7,VARS,SSR4,GFM2,YARS2,MRPS11,IGF2BP3,NAMPT,EIF2S2,GART,GATC,ATIC,UNC13A,HARS2,SHMT2,SELT,MRPL21,PPA1,PABPC1,RPL22L1,PCSK6,MTHFD1,RPS6KB2,GTF2H3,WARS2,PCCA,EIF4A2,MRPS10,ST6GALNAC3,MARS,EIF2A,CORIN,EIF5B,GUF1,ABCF1,NEU1,SMPDL3B,TARS,MRPL36,RARS,EPRS,MTHFD2,GSTO2,RPL28,SRP68,EIF2S1,CDKAL1,DPEP1,CNDP2,GGT7,SRP14 |
| 7.274e-03 | -4.92 | nuclear transcription factor complex | cellular component | GO:0044798 | 125 | 26 | 17570 | 2233 |
TCF12,GTF2H3,ATF4,PPARG,TAF1,TCF3,MED18,SOX4,SNAPC4,TAF9B,VDR,TAF2,TADA3,TRRAP,GTF2A1,HIF1A,TAF3,HIPK2,KLF4,TAF4,TBPL1,GTF2H1,GTF3C3,TAF12,DDIT3,CARM1 |
| 7.285e-03 | -4.92 | CD2AP (CD2-associated protein) | protein interactions | 23607 | 91 | 22 | 16036 | 2270 |
ARHGAP17,NRAS,PRDX6,SEC24D,TTC27,KHDRBS1,ARHGEF10,WDHD1,IMPDH2,IKBKAP,UBC,ASNS,SPAG9,ELP2,HNRNPR,SEC24C,KIAA0196,PFDN2,BRCC3,NOLC1,NIT1,GALE |
| 7.285e-03 | -4.92 | TCEB2 (transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)) | protein interactions | 6923 | 91 | 22 | 16036 | 2270 |
PRAME,TCEB3,LAGE3,AMBRA1,ARIH2,SEC31A,FAM50A,EPRS,MYBBP1A,COPS4,SOCS1,HIF1A,COPS3,COPS5,KLF4,CUL2,SOCS4,SOCS6,ASB3,COPS6,KMT2A,LRRC41 |
| 7.285e-03 | -4.92 | RBFOX2 (RNA binding protein, fox-1 homolog (C. elegans) 2) | protein interactions | 23543 | 91 | 22 | 16036 | 2270 |
MSI2,RBFOX2,KHDRBS1,BCS1L,ATXN1,MAPK1IP1L,MBNL1,PSMF1,VAC14,CLNS1A,CHAF1A,RPA1,RERE,POLR3D,UBAP2,HELZ,ATXN2,RIOK1,LARP4B,PRMT5,BMI1,SF3A1 |
| 7.306e-03 | -4.92 | Transcriptional regulation of white adipocyte differentiation | REACTOME pathways | R-HSA-381340 | 78 | 19 | 8202 | 1117 |
NCOR2,CHD9,PPARG,CDK4,MED27,MED13L,SMARCD3,MED18,MED16,ANGPTL4,SREBF2,KLF4,MED15,MED24,NCOR1,MED20,TBL1X,NR2F2,CARM1 |
| 7.310e-03 | -4.92 | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | 186 | 36 | 17758 | 2279 |
SLC37A3,CDC42EP2,ZCCHC8,ITFG1,PDE4B,PPHLN1,PPP2R2A,CHAC1,IKBIP,UBR5,GIT2,PITPNM1,IKBKB,GMDS,SLC35C2,ZNRD1,NAA35,ATP6V0D1,TRIM14,MCEE,FAM120B,TIMM8B,MINA,NLN,LIG4,PTPN12,ARRDC4,ZNF467,TMEM206,RARS,TPD52L2,RNF138,VPS13D,PURB,DHCR7,PRKAR2A |
| 7.310e-03 | -4.92 | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP | 186 | 36 | 17758 | 2279 |
TNIK,TTN,RAB11FIP4,GBF1,MRPS11,ABCA7,SKI,MLX,HR,SOCS1,PSMG4,NSRP1,LETM2,NDUFA6,MAP3K14,MEIS3,NT5E,MCEE,TSHZ1,VOPP1,OSBP2,ANKMY2,PTPN12,ZNFX1,MEGF11,IMPDH2,SLC26A11,ZFAND3,SMAD3,APBB3,SRD5A3,DIRAS1,PRRT3,TBL1X,SH3PXD2A,PDLIM5 |
| 7.310e-03 | -4.92 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | 186 | 36 | 17758 | 2279 |
UBN1,RHOBTB1,TFIP11,RPS29,PDE4B,TNXB,FOXP1,PIP4K2A,UBL5,SFR1,ELL,KDM2A,SOCS1,SLC38A2,CTR9,ETF1,MSI2,TUBA1A,SIGMAR1,MEF2D,IL6R,POLG2,FLVCR1,ANGPTL4,UBC,ZNF622,KPNA1,KLF4,SNX24,IFT140,PPP1R12B,RIOK1,IFITM2,WDR33,CCNB1IP1,LRCH1 |
| 7.310e-03 | -4.92 | GSE27786_LSK_VS_NKCELL_DN | MSigDB lists | GSE27786_LSK_VS_NKCELL_DN | 186 | 36 | 17758 | 2279 |
SLC37A3,CHMP2A,CERS5,DLGAP4,RCHY1,PLOD1,ST3GAL6,FOXP1,ABCA7,RTN1,MLX,MBD2,SNTG2,GLTP,CCDC124,ERRFI1,PLEKHA2,HTRA2,C19orf43,AKAP12,PTPN12,PLEKHM3,SON,MBNL2,PDE3B,MTHFD2,KIDINS220,DNAJC1,LSM14A,G6PD,CDK9,TNFRSF1A,PPP3CC,TAF12,CNDP2,DCAF5 |
| 7.310e-03 | -4.92 | GSE3982_BCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_BCELL_VS_NKCELL_UP | 186 | 36 | 17758 | 2279 |
LYRM4,TCF3,PDE4B,ISG20L2,SPATS2,SSBP2,RPAIN,PABPC4,AMPD3,THADA,TBC1D22A,MYH3,MRPS27,SHMT2,PPA1,NT5E,PTPRK,FDFT1,ADARB1,LAMC1,APTX,ZDHHC14,SERGEF,CLNS1A,TJAP1,ARPC3,HLA-DMA,PDLIM1,GTF2A1,HK2,SQLE,TRAF3,HMBS,PUS1,TSEN2,ADK |
| 7.310e-03 | -4.92 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_DN | 186 | 36 | 17758 | 2279 |
BCKDK,FAM189B,ACTR3,TMEM183A,DBF4,HLTF,PARN,LCLAT1,FAM8A1,ABL1,RAP1A,TRIAP1,SLC39A7,RNF111,PLEKHA2,TMEM14C,TERF2,ACSL5,FAM120B,PRIM2,EIF4A2,USP10,AKAP12,ATG12,BRCA1,SOX4,UBTF,GTF2A1,SYNCRIP,ADNP,SLC4A7,RIOK1,SENP3,MED20,C12orf45,USP15 |
| 7.310e-03 | -4.92 | GSE3982_MAST_CELL_VS_TH2_UP | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_UP | 186 | 36 | 17758 | 2279 |
ZNF516,JUP,PRDX6,SLC48A1,CLK1,KIAA0232,EVPL,TGFBR2,FLNB,LPIN1,ZNF804A,HARS2,PCOLCE2,VCL,RREB1,TBXAS1,PTK2,R3HDM2,VPS53,ANXA1,GNAI1,EPN2,KIDINS220,PMEPA1,HERC1,FAT1,ARNTL,TBX3,WDR7,SIL1,XPNPEP1,TPM1,NRP1,DOCK6,SMYD3,MID1 |
| 7.319e-03 | -4.92 | PDIESTERASE1 | prints domains | PR00387 | 19 | 6 | 4759 | 462 |
PDE2A,PDE4A,PDE9A,PDE10A,PDE8B,PDE4B |
| 7.325e-03 | -4.92 | RORA activates gene expression | REACTOME pathways | R-HSA-1368082 | 27 | 9 | 8202 | 1117 |
CHD9,NPAS2,ARNTL,SMARCD3,NCOR1,TBL1X,NRIP1,CPT1A,CARM1 |
| 7.328e-03 | -4.92 | cellular lipid metabolic process | biological process | GO:0044255 | 907 | 143 | 16441 | 2138 |
GGT1,PIGM,MVK,PRDX6,PRKAB2,TNFRSF21,CERS5,SIRT2,ABHD6,SYNJ1,LPIN1,FAAH2,ME1,SLC27A5,PRKACB,CARM1,ACADS,CHD9,SESN2,PPARG,GPCPD1,COL4A3BP,CAV1,BRCA1,PITPNB,ST3GAL5,GATA6,INSIG1,BDH2,TNFRSF1A,RBP1,PIGN,ST6GAL1,GPAT3,ALG8,PIK3R4,PLA2G12A,DPM3,ETFB,PI4KB,ISPD,PIGG,VAPB,GLTP,SYNJ2,PNPLA3,LPCAT1,FDFT1,HMGCR,FADS1,ALG6,ELOVL6,PCCA,RDH10,TBXAS1,SMARCD3,ST6GALNAC3,CPT1A,PLCB1,ACOXL,ANGPTL4,VAC14,RDH11,DAGLA,CAT,FAM135A,FDPS,DPEP1,PEX13,TBL1X,NCOR1,BPNT1,GGT7,PDSS2,CPT1C,MPI,NPAS2,PAFAH1B1,LPCAT2,TNXB,PIGH,LPCAT3,ST3GAL6,ARSJ,LCLAT1,PDE3A,DECR1,IDI1,CBR4,LPIN2,MGLL,HTRA2,LYST,ACSL5,MCEE,RAB7A,PI4KAP2,SNCA,PLIN2,TAMM41,PEMT,ABHD3,LARGE,SMG1,MORC2,SERINC5,NCOR2,INSIG2,IP6K2,LIAS,INPP1,PIP4K2A,SLC25A20,ADH5,PEX7,ACOT11,KDELC1,PTGS1,CPNE7,HSD17B12,LYPLA2,SLC25A1,FGF2,AGPAT4,NAPEPLD,MMAA,PIK3CB,SMPDL3B,ECH1,NEU1,TRIB3,RETSAT,ETFDH,ALG5,GPC2,DAGLB,SERINC1,ACOX1,SRD5A3,ATM,GPAM,PSAP,MTMR1 |
| 7.331e-03 | -4.92 | iron-sulfur cluster binding | molecular function | GO:0051536 | 64 | 16 | 16491 | 2164 |
PRIM2,PPAT,POLA1,ELP3,TYW1,LIAS,NDUFS7,FDX1,CIAPIN1,NUBPL,ETFDH,IREB2,NDUFV1,CDKAL1,FXN,MUTYH |
| 7.331e-03 | -4.92 | metal cluster binding | molecular function | GO:0051540 | 64 | 16 | 16491 | 2164 |
PRIM2,PPAT,POLA1,ELP3,TYW1,LIAS,NDUFS7,FDX1,CIAPIN1,NUBPL,ETFDH,IREB2,NDUFV1,CDKAL1,FXN,MUTYH |
| 7.339e-03 | -4.91 | secondary alcohol biosynthetic process | biological process | GO:1902653 | 38 | 11 | 16441 | 2138 |
LSS,IDI1,INSIG2,MVK,INSIG1,G6PD,FDPS,SQLE,DHCR7,FDFT1,HMGCR |
| 7.339e-03 | -4.91 | cholesterol biosynthetic process | biological process | GO:0006695 | 38 | 11 | 16441 | 2138 |
LSS,IDI1,INSIG2,MVK,INSIG1,G6PD,FDPS,SQLE,DHCR7,FDFT1,HMGCR |
| 7.349e-03 | -4.91 | AAGCACA,MIR-218 | MSigDB lists | AAGCACA,MIR-218 | 383 | 66 | 17758 | 2279 |
PTP4A1,SPRED2,BIRC6,NPAS2,PTPRA,RPS29,PPP2R2A,FAM13A,SYNJ1,SEMA6A,SLC39A1,WNT2B,KDM2A,SOCS6,MOSPD1,DBN1,GPM6A,ATXN1,SATB2,ARL5B,DLST,SERP1,DCBLD2,GNAI1,HTR7,ZNF236,HIC2,CSMD3,RPS6KB1,ZBTB11,BMI1,EFNB2,KHDRBS1,PAX2,MAPK8IP3,CENPB,RTN4,GDPD5,MBNL1,PRKCE,SACS,NEBL,HAS3,ATXN2,NDRG4,LARP4B,ZNF518B,LPCAT1,CPSF3L,NAV3,VOPP1,FOXN3,ZNF654,ATAT1,ARHGEF12,MBNL2,PHF6,SLC23A2,OXSR1,SPAG9,L3MBTL3,SLCO5A1,PURB,MBD6,GPAM,RABEP1 |
| 7.359e-03 | -4.91 | HSA | prosite domains | PS51204 | 4 | 3 | 11866 | 1504 |
SMARCA4,SRCAP,EP400 |
| 7.359e-03 | -4.91 | SCA7 | prosite domains | PS51505 | 4 | 3 | 11866 | 1504 |
ATXN7L1,ATXN7,ATXN7L2 |
| 7.362e-03 | -4.91 | uveal_tract | COSMIC cancer mutations | uveal_tract | 603 | 98 | 17775 | 2278 |
CGN,AMOTL1,ABCA3,PCNT,ARID2,NF1,OSBPL9,NTSR1,TRPM6,MKS1,PTPRG,SYNJ1,UBR5,GBF1,EDC3,SMARCB1,EXOC1,ZNHIT6,INTS12,GSTA4,RNF2,MET,KMT2A,DENND1A,MPST,KDM3B,SLC38A6,TNK2,EVL,SESN2,NRAS,KRT7,MIOS,VWCE,PREX1,ATG12,MCL1,KCNH3,BRCA1,KMT2C,TTC28,FLVCR1,MAK16,FGFR1,PDE8B,DCBLD2,UBTF,BRCA2,SUFU,ITGA2,CTAGE5,VPS13D,RUNX1,ANXA2,WDR66,PPIL3,SMG1,USP15,TNRC6A,XYLB,BRAF,PRAF2,PDE4B,MLH1,LIAS,IL17RE,ABL1,ABCA5,SEC24C,SEMA3D,NLGN3,PABPC1,HSD17B14,DDHD1,VOPP1,RANBP6,TRAPPC9,ZFYVE1,KCNMA1,OBSCN,MEN1,GPNMB,EXOG,ANXA1,CENPP,RETSAT,MYBBP1A,SPAG9,PALB2,HERC1,SDCCAG8,ATM,MYOM2,MTMR1,NUDT22,MAP2K4,ANAPC4,COG5 |
| 7.415e-03 | -4.90 | BROWNE_HCMV_INFECTION_20HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_UP | 231 | 43 | 17758 | 2279 |
EFNB2,BRAF,FOXO1,MAP3K13,B4GALT5,ARFIP2,KIF5C,SLC6A8,SAFB2,INPP1,GBF1,FAM49A,SLC25A20,ZNF37A,RNF40,UBE3A,YLPM1,RABGAP1L,TRMU,LTN1,CELF1,TMPO,PRPF19,PCGF3,MSX1,PDE4A,AKAP8L,WWC1,GNL1,ARHGAP32,KCNH2,TSR1,TOE1,IREB2,GTF2A1,E2F4,AGTPBP1,H2AFX,DLX2,MAP2K4,C18orf25,MAPT,SMG1 |
| 7.415e-03 | -4.90 | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | 231 | 43 | 17758 | 2279 |
RBM33,RHOBTB1,C1orf226,LAGE3,TUBB6,PTPRG,PABPC1L,FOXO3,TMCO6,IGSF1,FLNB,NAV1,HR,LONRF2,PMAIP1,LETM2,GREB1,NT5C,CD44,PNPLA3,NRIP1,MAP3K12,MYB,TEAD1,THSD4,CUX1,PSMG1,APTX,SOX4,SYT1,SMPDL3B,IRS1,RBBP8,ELP2,KDM4B,PDLIM1,E2F4,LARGE,FKBP5,SCARB1,MAPT,PKIB,ZSWIM6 |
| 7.418e-03 | -4.90 | BRCA1 (breast cancer 1, early onset) | protein interactions | 672 | 522 | 94 | 16036 | 2270 |
USP7,ACTG1,HECTD3,FANCD2,OLA1,NAT10,RSL1D1,CSNK2A1,SMARCA4,HLTF,FOSL2,KDM1A,WNT2B,SMARCB1,BRE,AP1M1,WIZ,ATRIP,UTP4,FAM184A,RFC4,SSFA2,CDK4,TCEB3,POU2F1,MARCKSL1,PSMG1,BRCA1,RBM28,SMAD3,VDR,BRCA2,CDC16,RBBP8,SMARCC1,RAD18,TP53BP1,E2F4,DNAJA3,H2AFX,BRCC3,TPM1,HERC2,JUP,ZCCHC8,SUPT6H,PAX2,UBXN1,DBF4,CENPB,PPHLN1,GTF2IRD1,MLH1,INPP1,FOXO3,POM121,ABL1,UBE3A,MYC,RDX,MAP3K14,NRIP1,CWF19L2,PABPC1,TERF2,CLK2,GATAD2B,PPP1R9B,DDX24,EIF4A2,ABCF2,OBSCN,SUPT5H,UBE2K,EIF5B,TARS,UBE2E1,POLR2A,UBC,RPA1,MRPL36,DYNC1H1,PALB2,RPL28,HIF1A,CDK9,HERC1,MSH3,GPN1,ATM,RWDD2B,PSAP,PGAM5,KIF1B |
| 7.421e-03 | -4.90 | telomeric heterochromatin | cellular component | GO:0031933 | 4 | 3 | 17570 | 2233 |
SIRT6,TNKS1BP1,ATRX |
| 7.421e-03 | -4.90 | histone locus body | cellular component | GO:0035363 | 4 | 3 | 17570 | 2233 |
ELL,ICE2,ZC3H8 |
| 7.421e-03 | -4.90 | nucleocytoplasmic shuttling complex | cellular component | GO:0031074 | 4 | 3 | 17570 | 2233 |
RAN,MYBBP1A,XPO5 |
| 7.421e-03 | -4.90 | t-UTP complex | cellular component | GO:0034455 | 4 | 3 | 17570 | 2233 |
HEATR1,UTP4,UTP15 |
| 7.421e-03 | -4.90 | NEGATIVE_REGULATION_OF_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_METABOLIC_PROCESS | 257 | 47 | 17758 | 2279 |
ZNF254,ID1,ZHX3,RBFOX2,KHDRBS1,NFX1,ID2,ATF7IP,BCOR,SIRT2,RSF1,PAIP2,TERF2IP,SNW1,SOCS1,VPS72,JAZF1,TIMELESS,ZEB1,ZNF148,NRIP1,TERF2,KAT8,KDM5B,NR6A1,LIMA1,FOXN3,ARID5B,CUX1,ATXN1,POU2F1,HDAC8,PRDM1,BRCA1,MEN1,SUPT5H,VDR,SMAD3,NSD1,SUPT4H1,DNAJC1,KLF4,PER1,TBX3,SET,RBPJ,KAT6A |
| 7.425e-03 | -4.90 | DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) | protein interactions | 1660 | 216 | 44 | 16036 | 2270 |
USP7,SART1,CUL7,CUL4A,FN1,UTP14A,KHDRBS1,AGO2,MBNL1,BIRC2,NOP56,IGF2BP3,PTRF,MBD2,GLYR1,RNF2,GEMIN4,YBX3,SRRM2,HNRNPM,TOP1,SPTAN1,RPS6KB2,RFC4,FBXW4,AKAP8L,SMARCAD1,TMEM126B,HSPA5,NFIA,BRCA1,SON,RHOT2,ABCF1,POLR2A,UBC,RPA1,RANBP2,HNRNPR,COPS5,CUL2,H2AFX,EIF2B3,ZMAT3 |
| 7.442e-03 | -4.90 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 687 | 110 | 17775 | 2278 |
PHF3,CELSR3,NF1,PDK4,DDR2,TRPM6,CSNK2A1,SMARCA4,RIPK1,RNF43,STK33,PRKCA,MAP2K3,RIOK2,ABL2,PRKD3,NEK6,RPS6KL1,IKBKB,ADCK4,MET,CDK12,CDK6,PRKACB,SRPK2,SLC38A6,TNK2,NRAS,BRD4,PDK1,NR6A1,PTPRM,CDK4,KSR2,MARCH6,BRCA1,SGK2,KMT2C,SON,STK10,FGFR1,SPOP,DYRK1B,PLIN2,SMAD3,CAMK2D,BRCA2,TRRAP,ELP2,CC2D1B,HIPK2,CSMD3,RPS6KB1,RIOK1,LAMA5,YEATS2,SMG1,SLC12A7,TNIK,BCKDK,BRAF,ZHX3,MAP3K13,CLK1,TAF1,CAMK1,TRIO,MRI1,PIK3R4,MED13L,MLH1,TGFBR2,CSNK1A1,CHD5,ARID1B,BZW2,ABL1,PRKCE,PRKCH,UBE3A,TANK,MAP3K12,RPS6KB2,CLK2,TOP1,DIS3L2,DDHD1,SIK3,CAMKK2,TEX14,OBSCN,R3HDM2,ARID1A,EIF5B,OXSR1,RETSAT,TRIB3,LRP1B,DSC2,GADD45A,ZZEF1,RIOK3,ATM,NR2F2,RPS6KC1,TBCK,ZAK,MAP2K4,PDE9A,STK4 |
| 7.442e-03 | -4.90 | pulmonary_blastoma | COSMIC cancer mutations | pulmonary_blastoma | 666 | 107 | 17775 | 2278 |
RTTN,SPRED2,ASH1L,SUCLG1,ARID2,NF1,WDR13,TNFRSF21,MYH9,ENAH,SPATS2,ST7L,BCOR,PTPRG,SEC16A,PIBF1,SEMA6A,DDX60L,JAG1,SLX4,IKZF5,ZFYVE28,MARVELD2,MYH3,CLCN6,ZNF85,KIAA0922,CPSF3,SRRM2,DENND1A,NAA35,FAM184A,LAMA4,NRAS,AKAP8L,STAMBP,KLHL23,CMIP,VWCE,ADAM32,ATP6V0A1,SATB2,AKAP13,MED16,TBC1D16,FKBP3,CHAF1A,BSN,DOT1L,CCDC3,DDAH2,ARHGAP21,SUFU,HLCS,KDM4B,ADNP,COPS5,CTAGE5,CSMD3,RNF130,LAMA5,MAPT,P2RY11,MEF2C,TMEM63C,BRAF,ST6GAL1,PIK3R4,SMG7,TRIM15,MED18,TGFBR2,ARID1B,ZNF594,ETFB,HR,SACS,CTNNBL1,NEBL,SEMA3D,WNT16,CALN1,SNX29,TRAPPC9,RB1CC1,WWC1,RSBN1,BMS1,PDE2A,EHBP1,MTR,NCDN,POLR3A,ANXA1,DYNC1H1,PRPF40B,NSD1,IREB2,MYBBP1A,HELZ,SYNCRIP,ATM,CASS4,AEN,NCOR1,ITGB4,COG5 |
| 7.442e-03 | -4.90 | pleura-pulmonary_blastoma | COSMIC cancer mutations | pleura-pulmonary_blastoma | 666 | 107 | 17775 | 2278 |
RTTN,SPRED2,ASH1L,SUCLG1,ARID2,NF1,WDR13,TNFRSF21,MYH9,ENAH,SPATS2,ST7L,BCOR,PTPRG,SEC16A,PIBF1,SEMA6A,DDX60L,JAG1,SLX4,IKZF5,ZFYVE28,MARVELD2,MYH3,CLCN6,ZNF85,KIAA0922,CPSF3,SRRM2,DENND1A,NAA35,FAM184A,LAMA4,NRAS,AKAP8L,STAMBP,KLHL23,CMIP,VWCE,ADAM32,ATP6V0A1,SATB2,AKAP13,MED16,TBC1D16,FKBP3,CHAF1A,BSN,DOT1L,CCDC3,DDAH2,ARHGAP21,SUFU,HLCS,KDM4B,ADNP,COPS5,CTAGE5,CSMD3,RNF130,LAMA5,MAPT,P2RY11,MEF2C,TMEM63C,BRAF,ST6GAL1,PIK3R4,SMG7,TRIM15,MED18,TGFBR2,ARID1B,ZNF594,ETFB,HR,SACS,CTNNBL1,NEBL,SEMA3D,WNT16,CALN1,SNX29,TRAPPC9,RB1CC1,WWC1,RSBN1,BMS1,PDE2A,EHBP1,MTR,NCDN,POLR3A,ANXA1,DYNC1H1,PRPF40B,NSD1,IREB2,MYBBP1A,HELZ,SYNCRIP,ATM,CASS4,AEN,NCOR1,ITGB4,COG5 |
| 7.450e-03 | -4.90 | CDH1 (cadherin 1, type 1) | protein interactions | 999 | 102 | 24 | 16036 | 2270 |
JUP,ACTG1,PTPRM,ACTR3,HSPA5,NKD2,SMAD7,DDR2,MYO7A,CSNK2A1,CAV1,ARHGAP32,IRS1,KLF4,SET,ZEB1,ADAM9,RNF2,ANP32B,MET,MAGI1,VCL,PTPN14,NIPSNAP1 |
| 7.450e-03 | -4.90 | ZC3H3 (zinc finger CCCH-type containing 3) | protein interactions | 23144 | 102 | 24 | 16036 | 2270 |
DDX24,ANKRD17,GLTSCR2,MRPS10,FARS2,RSL1D1,DKC1,RBM19,RBM28,HIST2H2AB,YARS2,PABPC4,AHCYL2,PUM3,MRPS11,KRI1,POP1,NOP16,PAK1IP1,DDX31,MRPL21,AHCYL1,ZC3H8,FTSJ3 |
| 7.450e-03 | -4.90 | ATCATGA,MIR-433 | MSigDB lists | ATCATGA,MIR-433 | 106 | 23 | 17758 | 2279 |
TTN,PRPF38B,LAMC1,CLYBL,FOXN3,KCNMA1,RSBN1,ARRDC4,CLINT1,UBR5,GABPB2,KIF16B,EPN2,RAP1A,UBR1,HIF1A,HNRNPR,CSMD3,CNOT6,CEP135,CEP170,TMEM33,TOP1 |
| 7.452e-03 | -4.90 | BROMODOMAIN_2 | prosite domains | PS50014 | 39 | 11 | 11866 | 1504 |
BAZ1A,ASH1L,BRD4,BAZ2B,TAF1,BAZ2A,SMARCA4,BRD9,KMT2A,BRWD3,TRIM66 |
| 7.462e-03 | -4.90 | CATTGTYY_V$SOX9_B1 | MSigDB lists | CATTGTYY_V$SOX9_B1 | 343 | 60 | 17758 | 2279 |
POLB,ZCCHC8,DBF4,PBX1,ADAMTS6,SPATS2,FOSL2,TMEM132A,RADIL,FAM49A,PRKCH,CHN1,CD96,NAV1,UBE3A,CYB5D1,PDS5B,ANKRD11,GREB1,IGF2BP1,CORO1A,ZNF710,VCL,HN1,TOP1,FGF9,TUBA1A,OSBP2,RREB1,SIRT6,TEAD1,ELOVL6,ABCF2,RDH10,TPM4,PTPN12,NXN,PRDM1,ARID1A,ZSCAN2,EHBP1,KLF6,FGFR1,PHF6,ZFAND3,DDAH2,SPAG9,GPC2,KPNA3,ADNP,SDCCAG8,ZNF436,HOXA3,CCDC85B,TRMT2A,PTPN4,YEATS2,KIF1B,MID1,KAT6A |
| 7.476e-03 | -4.90 | SFPQ (splicing factor proline/glutamine-rich) | protein interactions | 6421 | 158 | 34 | 16036 | 2270 |
CARS,SART1,CUL7,FN1,UTP14A,KHDRBS1,SIRT7,CSNK2A1,RNF43,SSR4,TIMM10,HNRNPA3,SNW1,PHF5A,ZMYM2,SRRM2,HNRNPM,SERBP1,TOP1,RPS6KB2,SF3A1,HN1,APEX1,PPARG,PSPC1,SON,TARS,UBC,YTHDF2,RPA1,HNRNPR,COPS5,ASB3,FUS |
| 7.500e-03 | -4.89 | binding, bridging | molecular function | GO:0060090 | 170 | 34 | 16491 | 2164 |
SH2D3A,KHDRBS1,MAPK8IP3,GAS6,EVPL,TRIM22,CSTA,STAM,PAG1,SH2B3,VPS18,CHN1,SHC1,ARHGAP1,CAV2,CRADD,SKAP2,ANK2,CUX1,WWC1,HSH2D,CAV1,MEN1,DSP,ANXA1,IRS1,BICD1,SPAG9,MPP7,STX1A,FSCN1,DUSP19,AP2S1,NMD3 |
| 7.520e-03 | -4.89 | GSE14000_UNSTIM_VS_4H_LPS_DC_UP | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_UP | 180 | 35 | 17758 | 2279 |
THOC5,LETM1,SHQ1,DCP1B,DBF4,NAT10,SMARCA4,LPCAT3,SLC25A44,PSMF1,LDOC1L,ATRIP,POLR3B,FTSJ3,EXOSC2,RFC3,KDM5B,GINS3,KIAA1143,PPAT,EPS15L1,TSN,HAUS6,LRRC8A,SATB2,IMPDH2,TAMM41,UBAP2,KDM4B,INTS5,MBTD1,BCAS3,H2AFX,SGSM2,CNOT6 |
| 7.524e-03 | -4.89 | 3'-5'-exoribonuclease activity | molecular function | GO:0000175 | 28 | 9 | 16491 | 2164 |
TOE1,EXOSC2,ERI1,CNOT6,EXOSC4,ERI3,NOCT,PARN,DIS3L2 |
| 7.524e-03 | -4.89 | thyroid hormone receptor binding | molecular function | GO:0046966 | 28 | 9 | 16491 | 2164 |
NSD1,HR,TRIP6,JMJD1C,MED24,MED16,NCOR1,FUS,OASL |
| 7.531e-03 | -4.89 | SWI/SNF complex | cellular component | GO:0016514 | 15 | 6 | 17570 | 2233 |
SMARCA4,SMARCD3,ARID1A,SMARCC1,ARID1B,SMARCB1 |
| 7.540e-03 | -4.89 | NUDT3 (nudix hydrolase 3) | protein interactions | 11165 | 40 | 12 | 16036 | 2270 |
DBN1,PRKD3,TUBA1A,APEX1,WDR74,UBR1,ITFG1,MCM5,XPNPEP1,MEX3B,PDCD5,REEP5 |
| 7.540e-03 | -4.89 | SPEN (spen family transcriptional repressor) | protein interactions | 23013 | 40 | 12 | 16036 | 2270 |
MSX2,NCOR2,TTN,CUL7,RBBP8,SIRT7,ATXN1,RBPJ,NCOR1,RUNX1,BMI1,SRA1 |
| 7.560e-03 | -4.88 | extraskeletal | COSMIC cancer mutations | extraskeletal | 942 | 146 | 17775 | 2278 |
CDCP1,PHF3,LUZP1,TNFRSF21,NAT10,TRPM6,ZNF107,NBEAL1,SEC16A,AMBRA1,TOM1L1,SMARCB1,PCYOX1L,EXOC1,PDZD2,ARHGAP18,ZFHX3,LONRF2,YLPM1,THADA,CHD2,SRRM2,LAMA4,FMNL3,NRAS,ANK2,KATNAL1,EHMT1,PLEKHM3,SGK2,KCNH2,TMEM206,PLCXD2,TCF7L1,AHNAK,BRCA2,TRRAP,CC2D1B,HIC2,ABCC3,NMD3,PTPN14,TNRC6A,VIPR1,HERC2,TMEM63C,WDR75,AK2,CELSR1,ANKRD17,TAF1,NHS,RSF1,RLF,ARID1B,ABCA7,DDX56,CNST,MCM5,ANGPT2,IFRD1,CAMKK2,RREB1,SETD2,ZBED4,CORIN,ABCF1,EPRS,DNAH17,KIAA1328,DDX10,PDLIM5,GALE,TCF12,SART1,ASH1L,OLFM2,DDX18,SPATA2L,MYO7A,TMEM104,ISG20L2,FAM122B,NECAP1,POP5,PTPRG,FLAD1,CHD7,ANKRD13A,FSIP2,PPFIBP1,ARMC5,VGF,MMP14,CORO1A,MET,MTHFD2L,CDK12,PRMT3,IPO11,PHLDB2,KMT2D,PCNXL2,ATP8B2,VDR,EXO1,TAF2,POLR3E,MDN1,FUS,YEATS2,CEP170,TMCC1,HMGA2,NOSTRIN,BRAF,C17orf80,MRI1,JMJD6,RTN4,MLH1,IKBKAP,GDPD5,BZW2,ADH5,RGS17,SACS,ZNF561,CTNNBL1,LRP2BP,HARS2,RDX,GREB1,PKNOX1,FAM120B,TEX14,ARHGAP32,RHOT2,ZNF407,CCDC150,ZNF155,ATM,MYOM2,RBM26,BRWD3,CORO2B |
| 7.563e-03 | -4.88 | heterocycle catabolic process | biological process | GO:0046700 | 392 | 68 | 16441 | 2138 |
LIN28B,PAPD4,DCP1B,RPS29,PPP2R2A,NT5C3A,HMOX2,TNKS1BP1,PDE3A,PABPC4,EDC3,AMPD3,RPS16,ERI1,NT5C,ETF1,OGG1,SKIV2L,SKIV2L2,ITPA,UPP1,ALDH1L2,NUDT15,PDE8B,HPRT1,NOCT,MUTYH,SMG1,DROSHA,TATDN3,PDE4B,SMG7,ZFP36L1,MLH1,RNASEH2B,PARN,DCTPP1,PDE10A,UPF2,EXOSC4,ERI3,NT5M,CNOT4,PABPC1,DIS3L2,NT5E,EXOSC2,WDR61,PDE4A,EIF4A2,DHX34,RNH1,EXOG,PDE2A,PDE3B,CTIF,POP1,CAT,KPNA1,RPL28,ZCCHC6,ATM,CNOT6,NCBP2,DPEP1,TATDN1,PDE9A,AGO3 |
| 7.571e-03 | -4.88 | DDT_dom | interpro domains | IPR004022 | 4 | 3 | 18293 | 2341 |
BAZ1A,BAZ2B,BAZ2A |
| 7.571e-03 | -4.88 | DUF4217 | interpro domains | IPR025313 | 4 | 3 | 18293 | 2341 |
DDX31,DDX10,DDX18 |
| 7.571e-03 | -4.88 | VPS13_C | interpro domains | IPR031645 | 4 | 3 | 18293 | 2341 |
VPS13D,VPS13C,VPS13B |
| 7.571e-03 | -4.88 | Beta_Casp | interpro domains | IPR022712 | 4 | 3 | 18293 | 2341 |
CPSF3,CPSF3L,INTS9 |
| 7.571e-03 | -4.88 | HSA_dom | interpro domains | IPR014012 | 4 | 3 | 18293 | 2341 |
SMARCA4,SRCAP,EP400 |
| 7.571e-03 | -4.88 | SCA7_dom | interpro domains | IPR013243 | 4 | 3 | 18293 | 2341 |
ATXN7L1,ATXN7,ATXN7L2 |
| 7.571e-03 | -4.88 | Lys_sp_deMease-like_dom | interpro domains | IPR013637 | 4 | 3 | 18293 | 2341 |
KDM5C,KDM5B,KDM5A |
| 7.571e-03 | -4.88 | Crontonase_C | interpro domains | IPR014748 | 4 | 3 | 18293 | 2341 |
HIBCH,AUH,ECH1 |
| 7.571e-03 | -4.88 | SHR-BD | interpro domains | IPR009543 | 4 | 3 | 18293 | 2341 |
VPS13D,VPS13C,VPS13B |
| 7.577e-03 | -4.88 | CUI_GLUCOSE_DEPRIVATION | MSigDB lists | CUI_GLUCOSE_DEPRIVATION | 60 | 15 | 17758 | 2279 |
SEPHS2,SARS,PRAME,SLC3A2,ASNS,GADD45A,ARNTL,RELB,KIF5C,HIST1H4J,PCK2,NEU1,DDIT4,PYCR1,NDUFB3 |
| 7.577e-03 | -4.88 | MORF_MSH2 | MSigDB lists | MORF_MSH2 | 60 | 15 | 17758 | 2279 |
RFC4,TRRAP,KHDRBS1,COPS5,SET,ALG8,GPN1,GTF2H1,SSBP1,POP5,MCM2,CLNS1A,CHAF1A,RPA1,NUDC |
| 7.603e-03 | -4.88 | anorectal | COSMIC cancer mutations | anorectal | 4 | 3 | 17775 | 2278 |
BRAF,CYLD,NRAS |
| 7.632e-03 | -4.88 | bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 928 | 144 | 17775 | 2278 |
CDCP1,PHF3,LUZP1,TNFRSF21,NAT10,TRPM6,ZNF107,NBEAL1,SEC16A,AMBRA1,TOM1L1,SMARCB1,PCYOX1L,EXOC1,PDZD2,ARHGAP18,ZFHX3,LONRF2,YLPM1,THADA,CHD2,SRRM2,LAMA4,FMNL3,NRAS,ANK2,KATNAL1,EHMT1,PLEKHM3,SGK2,KCNH2,TMEM206,PLCXD2,TCF7L1,AHNAK,BRCA2,TRRAP,CC2D1B,HIC2,ABCC3,NMD3,PTPN14,TNRC6A,VIPR1,HERC2,TMEM63C,WDR75,AK2,CELSR1,ANKRD17,TAF1,NHS,RSF1,RLF,ARID1B,ABCA7,DDX56,CNST,MCM5,ANGPT2,IFRD1,CAMKK2,RREB1,SETD2,ZBED4,CORIN,ABCF1,EPRS,DNAH17,KIAA1328,DDX10,PDLIM5,GALE,SART1,ASH1L,OLFM2,DDX18,SPATA2L,MYO7A,TMEM104,ISG20L2,FAM122B,NECAP1,POP5,PTPRG,FLAD1,CHD7,ANKRD13A,FSIP2,PPFIBP1,ARMC5,VGF,MMP14,CORO1A,MET,MTHFD2L,CDK12,PRMT3,IPO11,PHLDB2,KMT2D,PCNXL2,ATP8B2,VDR,EXO1,TAF2,POLR3E,MDN1,FUS,YEATS2,CEP170,TMCC1,NOSTRIN,BRAF,C17orf80,MRI1,JMJD6,RTN4,MLH1,IKBKAP,GDPD5,BZW2,ADH5,RGS17,SACS,ZNF561,CTNNBL1,LRP2BP,RDX,GREB1,HARS2,PKNOX1,FAM120B,TEX14,ARHGAP32,ZNF407,RHOT2,CCDC150,ZNF155,ATM,MYOM2,RBM26,BRWD3,CORO2B |
| 7.632e-03 | -4.88 | EWSR1 (EWS RNA binding protein 1) | protein interactions | 2130 | 240 | 48 | 16036 | 2270 |
USP7,NDUFA5,CUL7,MVK,CUL4A,FN1,TAF1,SEC24D,GPBP1L1,SIRT7,WDR37,CCDC7,HLTF,SSBP2,PRKCA,NLE1,SLC1A1,RIOK2,ABL1,NDUFV1,CNST,SUV39H2,VPS72,CFDP1,RNF2,CDK12,RPS6KB2,SEC24A,TMEM126A,SCMH1,MAPK1IP1L,TRIM37,SAP30BP,POLR3A,HERPUD1,POLR2A,RPA1,CXADR,GEMIN5,SUPT4H1,COPS5,CUL2,TRAF3,FUS,ANXA2,COPS6,BMI1,MTCH1 |
| 7.635e-03 | -4.87 | regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032434 | 147 | 30 | 16441 | 2138 |
TAF1,UBXN1,NKD2,TEX14,SMAD7,RCHY1,CSNK2A1,SIRT2,CAV1,UBE2K,MAD2L2,HERPUD1,UBE2E1,ARIH2,TRIB3,ANAPC1,KLHL22,CDC16,SMARCC1,NEK6,NSMCE2,WAC,ANAPC11,ANAPC10,SOCS4,MAD1L1,ATM,FHIT,CLU,ANAPC4 |
| 7.664e-03 | -4.87 | EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) | protein interactions | 1915 | 361 | 68 | 16036 | 2270 |
SART1,CUL7,CUL4A,ACTG1,BTBD2,POLR1A,NREP,UBR5,HSPA1A,PABPC4,NOP56,CAD,RPS16,ANKRD24,SSBP1,POLR3B,YARS,SRRM2,HTRA2,LAMA4,SNU13,NRAS,SIRT6,RAB7A,ABCC2,NUP214,SNCA,WARS,DLEU1,RANBP2,AHNAK,RBBP8,COPS5,H2AFX,PQBP1,FUS,MID1,NIFK,FN1,HSD17B10,VARS,PHGDH,RSRC1,SNW1,GART,ANXA7,EXOSC4,MAP3K14,FBL,PABPC1,RPS6KB2,CRADD,TSTA3,XPO5,LIG4,ISG15,POLR2A,ARIH2,NEU1,RPA1,MYBBP1A,GADD45A,POLE2,TRAP1,CUL2,PTPN4,KIF1B,AGO3 |
| 7.667e-03 | -4.87 | Cbx2 (chromobox 2) | protein interactions | 12416 | 10 | 5 | 16036 | 2270 |
PHC2,SCMH1,RNF2,BMI1,RING1 |
| 7.667e-03 | -4.87 | TIAM2 (T-cell lymphoma invasion and metastasis 2) | protein interactions | 26230 | 10 | 5 | 16036 | 2270 |
TNIK,RNF2,ANXA7,PARD3,H2AFX |
| 7.667e-03 | -4.87 | AKAP6 (A kinase (PRKA) anchor protein 6) | protein interactions | 9472 | 10 | 5 | 16036 | 2270 |
RYR2,PDE4A,PRKAR2A,MYC,DTNBP1 |
| 7.667e-03 | -4.87 | PCMTD2 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2) | protein interactions | 55251 | 10 | 5 | 16036 | 2270 |
TRIP13,VAC14,AUP1,CUL2,MRPS11 |
| 7.667e-03 | -4.87 | NEMF (nuclear export mediator factor) | protein interactions | 9147 | 10 | 5 | 16036 | 2270 |
LTN1,ZNF622,EIF2S2,DDX18,NOP56 |
| 7.667e-03 | -4.87 | C9orf16 (chromosome 9 open reading frame 16) | protein interactions | 79095 | 10 | 5 | 16036 | 2270 |
KRT20,IKBIP,CEP290,INPP1,DTNBP1 |
| 7.667e-03 | -4.87 | PSPH (phosphoserine phosphatase) | protein interactions | 5723 | 10 | 5 | 16036 | 2270 |
FLAD1,ATXN1,TIMM8B,SHC1,PHGDH |
| 7.683e-03 | -4.87 | V$TITF1_Q3 | MSigDB lists | V$TITF1_Q3 | 225 | 42 | 17758 | 2279 |
PRPF38B,ZBTB37,DLGAP4,FOXP1,POGZ,TECTA,NSRP1,CLCN6,WNT16,ETV1,MGLL,SRPK2,MAML3,DSC3,GPM6A,AEBP2,PXN,VPS37A,PTBP2,POLA1,TLE3,TRA2A,POU2F1,TOR1AIP2,IMPDH2,ZDHHC14,ODC1,ONECUT2,TMEM175,S100A16,RAD54B,MLLT10,NSD1,HERC1,LUC7L3,CSMD3,FIP1L1,BMI1,ZNF532,MID1,TNRC6A,MEF2C |
| 7.683e-03 | -4.87 | TGACGTCA_V$ATF3_Q6 | MSigDB lists | TGACGTCA_V$ATF3_Q6 | 225 | 42 | 17758 | 2279 |
CYLD,BRAF,ID1,NF1,MAP3K13,PAFAH1B1,ZBTB37,DDX19A,RPS29,OSBPL9,PPP2R2A,RCAN1,BRE,MCAM,SUV39H2,THADA,INTS7,VGF,IKBKB,ANAPC10,RELB,ZMYM2,CTC1,DDX28,SLC38A1,TEX14,LDHA,SULT4A1,PACRGL,MRRF,GNL1,SNAP25,MBNL2,NUP214,CAMK2D,DNTTIP1,SPAG9,TRAP1,PER1,VPS37B,UMPS,ZBTB11 |
| 7.708e-03 | -4.87 | V$CREBP1CJUN_01 | MSigDB lists | V$CREBP1CJUN_01 | 251 | 46 | 17758 | 2279 |
CYLD,BRAF,ID1,EGR1,NF1,MAP3K13,PAFAH1B1,ZBTB37,DDX19A,RPS29,OSBPL9,PPP2R2A,RCAN1,BRE,MCAM,SUV39H2,THADA,INTS7,SEC24C,VGF,IKBKB,ANAPC10,RELB,ZMYM2,CTC1,DDX28,STAG1,SLC38A1,TEX14,LDHA,SULT4A1,PACRGL,MRRF,GNL1,SNAP25,MBNL2,NUP214,DNTTIP1,CAMK2D,SPAG9,SYNCRIP,TRAP1,PER1,VPS37B,UMPS,ZBTB11 |
| 7.708e-03 | -4.87 | MORF_BRCA1 | MSigDB lists | MORF_BRCA1 | 251 | 46 | 17758 | 2279 |
CADM4,SPRED2,EP400,INSIG2,NF1,ATRX,SLC2A1,NFX1,KLHL18,BARX2,TTI1,RPS6KA5,CDC73,PSMF1,MGA,RAP1A,TSPAN2,SURF2,TBC1D22A,NCKIPSD,SYNJ2,CHD9,TTLL5,IL11RA,STAG1,PRIM2,RREB1,SIGMAR1,RB1CC1,POLA1,KIAA0586,SULT4A1,BRCA1,PIK3CB,ERC1,MLLT10,HTR7,TAF2,ZNF266,MSH3,HIC2,PPP1R12B,USP20,FNTB,RUNX1,SMG1 |
| 7.725e-03 | -4.86 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_UP | 193 | 37 | 17758 | 2279 |
NCOR2,MYCBP2,ASCC1,MCM6,TFIP11,RFX1,TTI1,SSR4,PAG1,DDIT4,RAP1A,ENTPD5,ATG3,RASSF3,GPR87,CORO1A,ANP32B,TSPAN14,TMEM14C,MCEE,MPP6,EIF4E3,LIMA1,CLYBL,CLNS1A,UBE2E1,MGAT2,TPD52L2,LUC7L3,ORC5,BCAS3,MPV17,SOCS4,ATM,SVIL,NDUFS5,SORCS2 |
| 7.725e-03 | -4.86 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | 193 | 37 | 17758 | 2279 |
TNIK,RWDD1,STX8,SUCLG1,PSTPIP2,NDUFB5,OLA1,SMAD7,IGF2BP3,S100A10,TRIAP1,PTGS1,AHCYL1,VCL,YARS,MGLL,PABPC1,ATF4,SKAP2,PSMA1,SUMO3,MRPS10,SOX4,ZNF91,SERP1,CLNS1A,ARL6IP5,ERVMER34-1,GLG1,MSH3,CLU,PTP4A2,TPM1,TROVE2,ZMAT3,SMG1,LPP |
| 7.725e-03 | -4.86 | GSE17721_CTRL_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDM_UP | 193 | 37 | 17758 | 2279 |
ITFG1,UBXN1,CERS5,ZNF280C,LCLAT1,PAG1,SKI,KRI1,KCTD11,PHF5A,C15orf40,DCTN4,SHMT2,BCAP29,ANP32B,NRIP1,TMEM14C,NAA35,SOBP,VPS37A,COL17A1,ELP3,ARID1A,IL6R,C1orf174,TMEM206,MGAT2,SRCAP,TSR1,ELP2,LUC7L3,PEMT,ATM,SVIL,NCOR1,HMBS,WDR33 |
| 7.744e-03 | -4.86 | V$OCT1_07 | MSigDB lists | V$OCT1_07 | 149 | 30 | 17758 | 2279 |
FAM98A,COMMD10,RANBP6,BDNF,TRERF1,TBXAS1,GRHL3,NFIA,MKS1,RCAN1,BCOR,PLCB1,NEDD4,NR2F1,STOML2,CXADR,MTUS1,ABL2,FAM50A,UBE3A,JAZF1,ANKRD11,PRICKLE2,ATM,TRAF3,ZNF148,RUNX1,ETV1,ZAK,MID1 |
| 7.772e-03 | -4.86 | upper_third | COSMIC cancer mutations | upper_third | 653 | 105 | 17775 | 2278 |
ZNF292,SART1,MVK,ZNF516,PHF3,BIRC6,UBN1,CACNA1H,ZNF107,NECAP1,SPATS2L,BCOR,SEC16A,STAM,DHX35,PCDH7,CAD,ABCA12,MRPS27,CCDC40,PCOLCE2,CEP135,ZMYM2,C6orf89,TMEM200A,GON4L,LIMA1,PTPRM,EHMT1,C5AR1,MEF2D,GALK2,BRCA1,KMT2C,TCTN1,VPS53,ASTN2,CHD3,DNAJA3,RLTPR,CSMD3,IFT140,TRMT2A,NFASC,MDN1,LAMA5,MUTYH,PTPN14,MORC2,SLC12A7,NCOR2,FN1,SUPT6H,TAF1,PIK3R4,SOGA1,GIGYF2,MTUS1,DOPEY1,SIPA1L3,PVRL3,UNC13A,VWDE,DSG2,ISPD,PNPLA3,AKAP11,NOM1,TMC7,FER1L5,TRAPPC9,DNMBP,RB1CC1,CRIM1,WDFY3,AOC2,TRA2A,TBXAS1,TEX14,DHX34,RYR2,SMARCD3,OBSCN,ARHGAP32,GUF1,RHOT2,ZNF407,ZNF850,PIK3CB,DYNC1H1,ZNF425,ATXN7,HELZ,L3MBTL3,HERC1,SPEN,FAT1,TBPL1,ATM,SVIL,C7orf50,WDR33,BRWD3,MMP16,LMBRD2 |
| 7.772e-03 | -4.86 | oesophagus-upper_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-upper_third-carcinoma-squamous_cell_carcinoma | 653 | 105 | 17775 | 2278 |
ZNF292,SART1,MVK,ZNF516,PHF3,BIRC6,UBN1,CACNA1H,ZNF107,NECAP1,SPATS2L,BCOR,SEC16A,STAM,DHX35,PCDH7,CAD,ABCA12,MRPS27,CCDC40,PCOLCE2,CEP135,ZMYM2,C6orf89,TMEM200A,GON4L,LIMA1,PTPRM,EHMT1,C5AR1,MEF2D,GALK2,BRCA1,KMT2C,TCTN1,VPS53,ASTN2,CHD3,DNAJA3,RLTPR,CSMD3,IFT140,TRMT2A,NFASC,MDN1,LAMA5,MUTYH,PTPN14,MORC2,SLC12A7,NCOR2,FN1,SUPT6H,TAF1,PIK3R4,SOGA1,GIGYF2,MTUS1,DOPEY1,SIPA1L3,PVRL3,UNC13A,VWDE,DSG2,ISPD,PNPLA3,AKAP11,NOM1,TMC7,FER1L5,TRAPPC9,DNMBP,RB1CC1,CRIM1,WDFY3,AOC2,TRA2A,TBXAS1,TEX14,DHX34,RYR2,SMARCD3,OBSCN,ARHGAP32,GUF1,RHOT2,ZNF407,ZNF850,PIK3CB,DYNC1H1,ZNF425,ATXN7,HELZ,L3MBTL3,HERC1,SPEN,FAT1,TBPL1,ATM,SVIL,C7orf50,WDR33,BRWD3,MMP16,LMBRD2 |
| 7.806e-03 | -4.85 | RNA phosphodiester bond hydrolysis | biological process | GO:0090501 | 111 | 24 | 16441 | 2138 |
EXOSC2,DROSHA,APEX1,AGO2,TSN,POP5,RNASEH2B,PARN,EDC3,RPP30,EXO1,POP1,TOE1,ERI1,NCBP2,CNOT6,EXOSC4,TSEN2,ERI3,CPSF3,WDR33,NOCT,AGO3,DIS3L2 |
| 7.811e-03 | -4.85 | PPP1R2 (protein phosphatase 1, regulatory (inhibitor) subunit 2) | protein interactions | 5504 | 45 | 13 | 16036 | 2270 |
TERF2IP,PPP1R9B,ZNF622,KDM2A,G6PD,SLK,CSNK2A1,RAP1GDS1,TATDN1,VCL,PPP1R9A,CIAPIN1,NCDN |
| 7.811e-03 | -4.85 | ELAC2 (elaC ribonuclease Z 2) | protein interactions | 60528 | 45 | 13 | 16036 | 2270 |
SMAD3,SARS,HARS,COPS5,ATIC,XPO5,TSN,CUX1,HSD17B10,TNPO3,FERMT2,RING1,MRPS30 |
| 7.811e-03 | -4.85 | CAP1 (CAP, adenylate cyclase-associated protein 1 (yeast)) | protein interactions | 10487 | 45 | 13 | 16036 | 2270 |
MCM6,PXN,FN1,ACTG1,TTC38,UCHL5,FMNL1,MCM5,SIRT7,TPM4,LIG4,MCM2,HTRA2 |
| 7.821e-03 | -4.85 | LGR4 (leucine-rich repeat containing G protein-coupled receptor 4) | protein interactions | 55366 | 199 | 41 | 16036 | 2270 |
MYCBP2,ACTG1,KHDRBS1,POLR1A,MYH9,URB1,PELP1,GIGYF2,CAD,YLPM1,NISCH,PIGG,GPATCH1,UPF2,KMT2A,AGL,FTSJ3,SCAF11,SKIV2L,PEA15,ANTXR2,SLC3A2,LAMC1,ZC3H18,CPT1A,EIF5B,POLR2A,UBC,GEMIN5,DDX3X,RANBP2,EPRS,ASCC3,MYBBP1A,KIDINS220,CHD3,SLC16A1,HEATR1,PDCD11,VWA8,N4BP2L2 |
| 7.833e-03 | -4.85 | HIST2H4A (histone cluster 2, H4a) | protein interactions | 8370 | 60 | 16 | 16036 | 2270 |
CUL7,BRD4,FN1,HDAC8,RPS6KA5,GADD45A,TAF3,TP53BP1,COPS5,E2F4,UCHL5,CUL2,SET,RAD51B,TBL1X,SAP30 |
| 7.833e-03 | -4.85 | WDR12 (WD repeat domain 12) | protein interactions | 55759 | 60 | 16 | 16036 | 2270 |
NIFK,DDX24,PSPC1,DDX19A,SIRT7,TSN,INPP1,PES1,VPS37B,RNF2,NOC3L,PUS1,BMI1,TXN2,FTSJ3,TOMM34 |
| 7.858e-03 | -4.85 | MARTIN_INTERACT_WITH_HDAC | MSigDB lists | MARTIN_INTERACT_WITH_HDAC | 44 | 12 | 17758 | 2279 |
NCOR2,CAMK2D,ATF4,CAMTA2,TP53BP1,HIF1A,DNAJB6,CAMK1,BCOR,NCOR1,NRIP1,PPA1 |
| 7.858e-03 | -4.85 | MODULE_284 | MSigDB lists | MODULE_284 | 44 | 12 | 17758 | 2279 |
CHD9,ASCC1,CUX1,ID2,PPP3CC,DKC1,SLC35D1,PPIP5K2,FXN,INPP1,PCSK6,SLC23A2 |
| 7.867e-03 | -4.85 | cell aging | biological process | GO:0007569 | 65 | 16 | 16441 | 2138 |
HMGA2,HSD17B10,ID2,CAV1,OPA1,BRCA2,NSMCE2,DNAJA3,ARNTL,TBX3,H2AFX,ATM,WNT16,CTC1,KAT6A,TERF2 |
| 7.902e-03 | -4.84 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | MSigDB lists | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | 15 | 6 | 17758 | 2279 |
GLS,SNAP25,STX1A,SYT1,SLC1A1,SLC38A2 |
| 7.927e-03 | -4.84 | ANP32A (acidic nuclear phosphoprotein 32 family member A) | protein interactions | 8125 | 55 | 15 | 16036 | 2270 |
OXSR1,TPD52L2,KPNA1,APEX1,PPARG,VPS72,SMARCAD1,SET,ATXN1,ANP32B,AHCYL1,PDLIM5,SRP14,BAG1,CHAF1A |
| 7.927e-03 | -4.84 | CLK3 (CDC like kinase 3) | protein interactions | 1198 | 55 | 15 | 16036 | 2270 |
FAM192A,USP7,KPNA1,TRA2A,TNPO3,FKBP5,USP11,PRMT5,SRRM2,PABPC1,PABPC4,NEDD4,TERF2,CLK2,SRPK2 |
| 7.927e-03 | -4.84 | DMAP1 (DNA methyltransferase 1 associated protein 1) | protein interactions | 55929 | 55 | 15 | 16036 | 2270 |
EP400,SRCAP,TRRAP,BRD4,ACTG1,VPS72,MYC,SMARCAD1,CFDP1,H2AFX,RNF2,ANP32B,TOMM34,CHAF1A,DENR |
| 7.929e-03 | -4.84 | DBNL (drebrin-like) | protein interactions | 28988 | 50 | 14 | 16036 | 2270 |
TERF2IP,HERC2,P3H1,UBE3A,KDM5B,ALAD,ACD,RB1CC1,CDK4,USP20,GPN1,RANGAP1,LRSAM1,LPP |
| 7.929e-03 | -4.84 | human chr6p24.2 | chromosome location | human chr6p24.2 | 9 | 4 | 26250 | 2590 |
PAK1IP1,SYCP2L,GCNT2,TMEM14C |
| 7.930e-03 | -4.84 | activation of meiosis | biological process | GO:0090427 | 4 | 3 | 16441 | 2138 |
MSX2,MSX1,PLCB1 |
| 7.930e-03 | -4.84 | positive regulation of histone H2B ubiquitination | biological process | GO:2001168 | 4 | 3 | 16441 | 2138 |
RNF40,CTR9,CDK9 |
| 7.930e-03 | -4.84 | regulation of glucose mediated signaling pathway | biological process | GO:1902659 | 4 | 3 | 16441 | 2138 |
SMARCA4,UBTF,SMARCB1 |
| 7.930e-03 | -4.84 | immunoglobulin V(D)J recombination | biological process | GO:0033152 | 4 | 3 | 16441 | 2138 |
LIG4,POLB,TCF3 |
| 7.930e-03 | -4.84 | 10-formyltetrahydrofolate metabolic process | biological process | GO:0009256 | 4 | 3 | 16441 | 2138 |
MTHFD2L,ALDH1L2,MTHFD1 |
| 7.930e-03 | -4.84 | L-serine biosynthetic process | biological process | GO:0006564 | 4 | 3 | 16441 | 2138 |
SHMT2,PSAT1,PHGDH |
| 7.930e-03 | -4.84 | regulation of histone H2B ubiquitination | biological process | GO:2001166 | 4 | 3 | 16441 | 2138 |
RNF40,CTR9,CDK9 |
| 7.930e-03 | -4.84 | negative regulation of histone H3-K4 methylation | biological process | GO:0051572 | 4 | 3 | 16441 | 2138 |
BCOR,BRCA1,KDM1A |
| 7.956e-03 | -4.83 | RNA Polymerase I Transcription Termination | REACTOME pathways | R-HSA-73863 | 32 | 10 | 8202 | 1117 |
UBTF,GTF2H3,PTRF,GTF2H2C,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 7.957e-03 | -4.83 | VPS13_C | pfam domains | PF16909 | 4 | 3 | 16629 | 2165 |
VPS13D,VPS13C,VPS13B |
| 7.957e-03 | -4.83 | PLU-1 | pfam domains | PF08429 | 4 | 3 | 16629 | 2165 |
KDM5C,KDM5B,KDM5A |
| 7.957e-03 | -4.83 | DUF4217 | pfam domains | PF13959 | 4 | 3 | 16629 | 2165 |
DDX31,DDX10,DDX18 |
| 7.957e-03 | -4.83 | SHR-BD | pfam domains | PF06650 | 4 | 3 | 16629 | 2165 |
VPS13D,VPS13C,VPS13B |
| 7.957e-03 | -4.83 | DDT | pfam domains | PF02791 | 4 | 3 | 16629 | 2165 |
BAZ1A,BAZ2B,BAZ2A |
| 7.957e-03 | -4.83 | Beta-Casp | pfam domains | PF10996 | 4 | 3 | 16629 | 2165 |
CPSF3,CPSF3L,INTS9 |
| 7.957e-03 | -4.83 | SCA7 | pfam domains | PF08313 | 4 | 3 | 16629 | 2165 |
ATXN7L1,ATXN7,ATXN7L2 |
| 7.957e-03 | -4.83 | MATH | pfam domains | PF00917 | 4 | 3 | 16629 | 2165 |
USP7,TRIM37,SPOP |
| 7.957e-03 | -4.83 | HSA | pfam domains | PF07529 | 4 | 3 | 16629 | 2165 |
SMARCA4,SRCAP,EP400 |
| 7.963e-03 | -4.83 | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDM_DN | 187 | 36 | 17758 | 2279 |
SEPHS2,PTCD2,EGR1,POLR1A,CERS5,HECTD3,LAMTOR3,HES6,ZFP36L1,XPO7,PRPF39,MPHOSPH10,RABGAP1L,KIAA0922,TSPAN14,TMEM14C,PRMT3,CSGALNACT2,CDC37,SESN2,PPARG,GPCPD1,PACS1,RHOT2,MGST1,USP36,RPA1,POLR3G,RPL28,NSF,ZNF330,AGTPBP1,SRD5A3,SLCO5A1,TMEM141,NR2C2AP |
| 7.963e-03 | -4.83 | GSE14308_TH2_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_TH2_VS_INDUCED_TREG_DN | 187 | 36 | 17758 | 2279 |
PCNT,PRKAB2,TRIO,CLSTN2,MAP1S,RNF24,ZNF483,NDUFV1,NOP16,CNIH3,COPS3,NISCH,BUD31,WDR60,CPSF3,TERF2,ACSL5,WDR61,RNMT,TSTA3,C2orf76,GNL3,C19orf43,CPOX,ANKDD1B,C11orf49,ARID1A,ARL5B,SLC26A11,FSCN1,LRRC40,RLTPR,HK2,CDKAL1,TXN2,ZBTB24 |
| 7.963e-03 | -4.83 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 187 | 36 | 17758 | 2279 |
MPI,ID1,ATRX,PTPRA,H2AFJ,NUP43,TMCO6,SFR1,NPRL2,CBR4,NISCH,MAD1L1,HKR1,PPM1K,SF3A1,SPTAN1,ZNF124,PARP2,EXOC6B,JMJD1C,LDHA,SUMO3,C11orf49,CPT1A,NAPEPLD,ZNF251,UBTF,NSF,NSMCE1,LRRC40,BDH2,CDKAL1,SGSM2,IGBP1,RFXAP,PKIB |
| 7.963e-03 | -4.83 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP | 187 | 36 | 17758 | 2279 |
SEPHS2,SARS,ID1,ATRX,VPS45,CENPB,LAGE3,GTF2IRD1,IKBKAP,CMTM3,FRRS1,SKI,CEP164,RNF141,THAP4,MYC,LRSAM1,NUDC,SRPK2,USE1,RFC4,PPARG,ANKMY2,EIF4A2,ATG12,SLC50A1,TBC1D2,PDE8B,ZNF708,ZNF622,ATAD5,ALAD,COQ9,C7orf50,TSEN2,DHCR7 |
| 7.963e-03 | -4.83 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | 187 | 36 | 17758 | 2279 |
TNNC1,SPRED2,ABHD6,PSMF1,PDE3A,EDC3,NEBL,MYC,BANF1,PMPCA,TSPAN14,ATP6V0D1,PABPC1,SLC25A1,TERF2,VOPP1,GPM6A,RBCK1,CAMKK2,TLE3,LDHA,ATXN1,KLF6,ZNF91,STK10,SLC9A5,ISG15,PGD,YIF1A,TPD52L2,ETFDH,GALNT10,MACROD1,BLMH,TROVE2,P2RY11 |
| 7.963e-03 | -4.83 | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | 187 | 36 | 17758 | 2279 |
LYRM4,LAGE3,PLA2G12A,RSF1,PRKCA,GDPD5,REEP5,UBR5,MFHAS1,DCTPP1,SH2B3,DDX56,DCTN4,HIRIP3,ZNF85,PPA1,TRIP13,SPTAN1,TOP1,LDHA,USP10,IMPDH2,PNN,MCM2,SUPT5H,DENND4A,RBM28,RAD54B,BAZ2B,POLE2,SERF2,SPEN,ZCCHC6,UMPS,MED20,BLMH |
| 7.963e-03 | -4.83 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 187 | 36 | 17758 | 2279 |
GGT1,ZNF292,BANP,NCOR2,CYLD,BRAF,MAP3K13,TRAK1,PDE4B,BHLHE40,NBEAL1,RLF,BMP6,MAP2K3,CYB5D1,PPCDC,CHD2,FUT11,PABPC1,BRD4,SLC3A2,PDK1,DDX41,CUX1,KCNH2,SRA1,SERP1,ABCF1,GZF1,ZBTB25,OXSR1,GNG2,SPAG9,INSIG1,RBPJ,PTP4A2 |
| 7.966e-03 | -4.83 | VALK_AML_CLUSTER_8 | MSigDB lists | VALK_AML_CLUSTER_8 | 24 | 8 | 17758 | 2279 |
OSBP2,PBX1,ARHGEF12,SLC6A8,TMEM158,TSPAN5,SNCA,MOSPD1 |
| 7.966e-03 | -4.83 | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN | 24 | 8 | 17758 | 2279 |
RAP1A,GATA6,UBAP2L,ID2,ZNF148,BRCA1,SEPT5,MYB |
| 7.966e-03 | -4.83 | chr10p11 | MSigDB lists | chr10p11 | 24 | 8 | 17758 | 2279 |
DNAJC1,CUL2,SVIL,ZEB1,CCDC7,PARD3,SPAG6,ZNF37A |
| 7.966e-03 | -4.83 | ORGANELLE_OUTER_MEMBRANE | MSigDB lists | ORGANELLE_OUTER_MEMBRANE | 24 | 8 | 17758 | 2279 |
RETSAT,MCL1,FIS1,OPA1,DHCR7,RHOT2,TOMM34,MFN2 |
| 7.966e-03 | -4.83 | RNA_CATABOLIC_PROCESS | MSigDB lists | RNA_CATABOLIC_PROCESS | 24 | 8 | 17758 | 2279 |
POP1,AUH,SMG7,UPF2,HSPA1A,SMG1,PABPC4,HSPA1B |
| 8.001e-03 | -4.83 | MODULE_252 | MSigDB lists | MODULE_252 | 232 | 43 | 17758 | 2279 |
MCM6,KHDRBS1,CSNK2A1,ZFP36L1,MLH1,HLTF,SNW1,SRSF2,HR,VPS72,MYC,RAN,CMPK1,TRIP13,TMPO,SRPK2,SAP30,RFC4,MSX1,RFC3,ZNF124,PRIM2,APEX1,RNMT,STAMBP,POLA1,CDK4,TSN,WDHD1,PNN,SOX4,DSP,CHAF1A,ZBTB25,RPA1,POLE2,CCNT1,HNRNPR,PER1,TAF4,H2AFX,NCBP2,BMI1 |
| 8.005e-03 | -4.83 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 245 | 45 | 17758 | 2279 |
ADAM19,CHST11,FOXO1,RHOBTB1,ID2,MYH9,SPATS2L,PRKCA,INPP1,FAM49A,PCDH7,ECM1,MCAM,NEBL,S100A10,FGGY,PTGS1,MET,CD44,CAV2,HMGCR,PEA15,ANK2,PCCA,MED27,ARID5B,TPM4,RAP1B,AKAP12,PHACTR2,CAV1,ST3GAL5,TCF7L2,DKK1,TCF7L1,MSX2,PXDN,GADD45A,KLF4,GALNT10,NFASC,BMP4,NR2F2,MMP16,AP2S1 |
| 8.008e-03 | -4.83 | LRR1 (leucine rich repeat protein 1) | protein interactions | 122769 | 22 | 8 | 16036 | 2270 |
COPS4,COPS5,COPS3,CUL2,COPS7B,COPS6,PTPN14,TRIP13 |
| 8.008e-03 | -4.83 | MARCH7 (membrane associated ring finger 7) | protein interactions | 64844 | 22 | 8 | 16036 | 2270 |
USP7,UBXN1,RNF111,TGFBR2,UBE2K,MAPT,UBE2E1,UBC |
| 8.013e-03 | -4.83 | FOSTER_TOLERANT_MACROPHAGE_DN | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_DN | 398 | 68 | 17758 | 2279 |
ARHGAP26,FAM208B,FEZ2,LUZP1,TUBB6,UBTD2,RAC3,HSPA1A,FLNB,PHC2,CHD7,NEK6,SOCS1,S100A10,PPFIBP1,PLEKHA4,PPM1K,EVL,GCNT2,AEBP2,UPP1,TOR1AIP2,CAV1,ODC1,SLC39A14,RANBP2,CAMK2D,KPNA3,ARL4A,SLC4A7,FKBP5,PRPF4,LRCH1,CHST11,B4GALT5,KHDRBS1,PDE4B,MED13L,RCAN1,FOXP1,INPP1,MTUS1,NAMPT,ERRFI1,PLEKHA2,PPA1,FMNL2,MYO10,TRA2A,TLE3,USP42,TPM4,HSPA1B,ATP9B,DYNC1H1,MPP7,FSCN1,PMEPA1,VCAN,ZCCHC6,CSRNP1,TMEM219,SLC16A1,APAF1,IQSEC2,PDLIM5,MAP2K4,KAT6A |
| 8.017e-03 | -4.83 | PDIA6 (protein disulfide isomerase family A, member 6) | protein interactions | 10130 | 81 | 20 | 16036 | 2270 |
KLHL24,CUL7,FN1,ZHX3,XPO5,HSPA5,METTL23,CSNK2A1,BTBD9,HNRNPLL,CLNS1A,TTC1,TPD52L2,P3H1,GTF2A1,COPS5,H2AFX,SERPINH1,PRMT5,IGBP1 |
| 8.017e-03 | -4.83 | USP4 (ubiquitin specific peptidase 4 (proto-oncogene)) | protein interactions | 7375 | 81 | 20 | 16036 | 2270 |
PDK1,PRPF31,DCP1B,LGALS1,RIPK1,PLOD1,ADSL,UBC,TCF7L2,EDC3,ANXA7,IKBKB,TNFRSF1A,PRPF4,PSAP,USP11,NOLC1,LAMA5,PRPF19,USP15 |
| 8.017e-03 | -4.83 | ASNS (asparagine synthetase (glutamine-hydrolyzing)) | protein interactions | 440 | 81 | 20 | 16036 | 2270 |
GARS,PXN,TTC27,PAFAH1B1,SIRT7,OLA1,ATXN1,RAP1GDS1,PHGDH,AARS,MAT2A,EPRS,AHNAK,TRAP1,WDR27,COPS5,XPNPEP1,VCL,NMD3,GALE |
| 8.017e-03 | -4.83 | ZYX (zyxin) | protein interactions | 7791 | 81 | 20 | 16036 | 2270 |
GARS,PXN,FN1,TPM4,FERMT2,ATXN1,ENAH,VIM,TARS,GART,NEBL,SREBF2,FSCN1,SEC24C,TPM1,AHCYL1,PDLIM5,TOMM34,NUDC,RABEPK |
| 8.017e-03 | -4.83 | HNRNPH3 (heterogeneous nuclear ribonucleoprotein H3 (2H9)) | protein interactions | 3189 | 81 | 20 | 16036 | 2270 |
CUL7,CUL4A,FN1,UTP14A,SF3A3,SEC16A,NLE1,MBNL1,HNRNPA3,PHF6,HNRNPR,HNRNPH3,COPS5,CUL2,H2AFX,RNF2,SSBP1,COPS6,ZMYM2,SRRM2 |
| 8.140e-03 | -4.81 | farnesyltranstransferase activity | molecular function | GO:0004311 | 4 | 3 | 16491 | 2164 |
FNTB,COX10,FDFT1 |
| 8.141e-03 | -4.81 | chiasm | COSMIC cancer mutations | chiasm | 11 | 5 | 17775 | 2278 |
RNF130,BRAF,KIAA1549,GNAI1,CLCN6 |
| 8.190e-03 | -4.80 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | MSigDB lists | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | 11 | 5 | 17758 | 2279 |
ADSL,GART,IMPDH2,PPAT,ATIC |
| 8.190e-03 | -4.80 | NUCLEAR_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | NUCLEAR_UBIQUITIN_LIGASE_COMPLEX | 11 | 5 | 17758 | 2279 |
BRE,BRCA1,BRCC3,ANAPC4,ANAPC11 |
| 8.190e-03 | -4.80 | FUNG_IL2_SIGNALING_1 | MSigDB lists | FUNG_IL2_SIGNALING_1 | 11 | 5 | 17758 | 2279 |
DKC1,NOLC1,NOP16,MAT2A,NOP56 |
| 8.190e-03 | -4.80 | PROTEIN_TARGETING_TO_MITOCHONDRION | MSigDB lists | PROTEIN_TARGETING_TO_MITOCHONDRION | 11 | 5 | 17758 | 2279 |
TAMM41,TIMM17A,TOMM34,MFN2,TIMM44 |
| 8.198e-03 | -4.80 | homeostasis of number of cells | biological process | GO:0048872 | 185 | 36 | 16441 | 2138 |
POLB,KMT2E,PDE4B,ID2,JMJD6,NLE1,RAC3,GIGYF2,PTPN2,RRN3,AMPD3,PMAIP1,ATXN2,IKBKB,UBAP2L,CORO1A,SOX6,PKNOX1,MYB,MTHFD1,SLC40A1,FLVCR1,RPA1,EXOC6,ANXA1,SKIL,HIF1A,L3MBTL3,DNAJA3,G6PD,HIPK2,RLTPR,BMP4,NCOR1,ZC3H8,MEF2C |
| 8.211e-03 | -4.80 | DELPUECH_FOXO3_TARGETS_DN | MSigDB lists | DELPUECH_FOXO3_TARGETS_DN | 39 | 11 | 17758 | 2279 |
EFNB2,SLC7A1,C6orf48,MTHFD2,GADD45A,APEX1,SHMT2,IMPDH2,PCK2,AARS,PYCR1 |
| 8.211e-03 | -4.80 | RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 | 39 | 11 | 17758 | 2279 |
ZBTB17,TCF12,EXO1,SRSF2,ID1,RAB7A,EIF4A2,CENPB,FOSL2,BMI1,SMARCB1 |
| 8.229e-03 | -4.80 | Metabolic pathways | KEGG pathways | hsa01100 | 1214 | 181 | 6908 | 881 |
SRM,CYP24A1,GGT1,PIGM,MVK,PRDX6,POLR1A,CERS5,NT5C3A,COX10,SYNJ1,AHCYL2,LPIN1,AMPD3,ATP5G2,PPCDC,HYAL1,SUCLG2,ME1,POLR3B,POLE3,SLC27A5,NDUFA6,GALNT18,ZNRD1,MPST,CSGALNACT2,ACADS,GCNT2,ITPA,UPP1,MTHFD1L,ODC1,DLST,ST3GAL5,PYCR1,GLS,LSS,HPRT1,HLCS,BDH2,GALNT10,SEPHS2,XYLB,AOC3,PIGN,AK2,ST6GAL1,GPAT3,AK6,ALG8,HSD17B10,PLA2G12A,DPM3,PHGDH,NDUFS7,NAMPT,PI4KB,ATIC,SYNJ2,ALDH18A1,GMDS,PNPLA3,LPCAT1,COQ3,AGL,POLR1E,PRPS1,ATP6V0D1,NT5E,HMGCR,MTHFD1,FDFT1,ALG6,PRIM2,TSTA3,PPAT,POLA1,AOC2,PCCA,IDH3G,RDH10,TBXAS1,ST6GALNAC3,IMPDH2,PLCB1,MTR,PGD,RDH11,MGAT2,EPRS,MTHFD2,NME7,FDPS,HK2,SQLE,UMPS,HMBS,BPNT1,GGT7,CNDP2,DHCR7,GALE,SDSL,MPI,NDUFA5,SUCLG1,PAFAH1B1,ATP6V1A,LPCAT2,UROD,NDUFB5,PIGH,ST3GAL6,LCLAT1,NDUFB3,FLAD1,CAD,IDI1,ASNS,PYCRL,LPIN2,NT5C,HIBCH,CMPK1,AHCYL1,MGLL,MTHFD2L,ACSL5,MCEE,CPOX,ATP6V0A1,POLG2,MAT2A,HSD3B7,TPK1,ATP5D,HYAL3,ALAD,DCXR,G6PD,PEMT,FAHD1,DMGDH,AUH,MRI1,TKFC,APRT,LIAS,INPP1,MAN1A1,DCTPP1,ADH5,POLR3D,GART,NDUFV1,GATC,SHMT2,PHYKPL,PTGS1,POLR1B,PCK2,NT5M,HSD17B12,PSAT1,AGPAT4,LDHA,ADSL,POLR2A,POLR3A,POLR3G,ALG5,NME1-NME2,POLE2,ACOX1,NDUFS5,GPAM,POLR1C,MTMR1,ADK,GCSH |
| 8.233e-03 | -4.80 | human chr3p14 | chromosome location | human chr3p14 | 5 | 3 | 26250 | 2590 |
PSMD6-AS2,EIF4E3,ARL6IP5 |
| 8.233e-03 | -4.80 | ARPC1A (actin related protein 2/3 complex subunit 1A) | protein interactions | 10552 | 31 | 10 | 16036 | 2270 |
TPD52L2,CUL7,ACTR3,OLA1,TRMT10A,CNDP2,ACTR3B,MTR,SH3GL1,ARPC3 |
| 8.233e-03 | -4.80 | MRM1 (mitochondrial rRNA methyltransferase 1) | protein interactions | 79922 | 31 | 10 | 16036 | 2270 |
GLS,UBR1,MTIF2,ZZEF1,CUL2,HECTD3,TOP3A,BMI1,UQCC1,LYRM7 |
| 8.233e-03 | -4.80 | POLR3D (polymerase (RNA) III (DNA directed) polypeptide D, 44kDa) | protein interactions | 661 | 31 | 10 | 16036 | 2270 |
MSX2,TSR1,APEX1,RBFOX2,POLR3E,CRCP,POLR3B,POLR1C,POLR3A,POLR3G |
| 8.233e-03 | -4.80 | DGCR8 (DGCR8 microprocessor complex subunit) | protein interactions | 54487 | 31 | 10 | 16036 | 2270 |
DROSHA,HNRNPR,PYCRL,HSPA5,NAT10,PRPF4,FUS,PLEK2,BMI1,SRPK2 |
| 8.239e-03 | -4.80 | V$SRF_Q4 | MSigDB lists | V$SRF_Q4 | 213 | 40 | 17758 | 2279 |
TNNC1,EGR1,NPAS2,ATRX,RSF1,FOXP1,MBNL1,TADA3,VGF,TANK,MMP14,SHF,CHD2,NLGN3,SERPINH1,CALN1,VCL,MSX1,PPARG,TLE3,NPM3,GRHL3,AKAP12,MCL1,KRTCAP2,KLF6,NR2F1,RERE,HERC1,H2AFX,HOXA3,SVIL,TBL1X,NR2F2,TPM1,PDLIM5,ZAK,MID1,RAB30,LPP |
| 8.249e-03 | -4.80 | SUMO1 (small ubiquitin-like modifier 1) | protein interactions | 7341 | 159 | 34 | 16036 | 2270 |
NCOR2,CUL7,SLC2A1,SREBF2,USPL1,RNF111,ZCCHC7,ZMYM2,PABPC1,SOX6,CASP8AP2,PRKACB,TOP1,MYB,MSX1,TFCP2,ZMYM5,ATXN1,MAPK1IP1L,RANGAP1,BRCA1,C11orf65,UBC,RAD54B,CHAF1A,TOE1,ATXN7,RANBP2,CHD3,HIPK2,TNFRSF1A,PFDN2,C18orf25,PPIL3 |
| 8.254e-03 | -4.80 | OSMAN_BLADDER_CANCER_UP | MSigDB lists | OSMAN_BLADDER_CANCER_UP | 385 | 66 | 17758 | 2279 |
ACTR3,RING1,YLPM1,JAZF1,GLYR1,ZNF148,HCFC2,LYST,TBC1D8,TMPO,SAP30,SEC24A,CHD9,FAM172A,COL4A3BP,ATXN1,AKAP13,RAB10,ZFAND3,KPNA3,HIPK2,XRCC4,TROVE2,ZMAT3,NMD3,SMG1,TMEM33,KLHL24,ANKRD17,VTA1,KHDRBS1,SESTD1,SMAD7,ATF7IP,RSF1,CSNK1A1,MBNL1,TNPO3,CCDC88C,LDLRAD3,CD44,TTC17,PRF1,NRIP1,SERBP1,TOP1,SCAF11,CAMKK2,HAUS6,USP42,LDHA,TPM4,MRPS10,RNH1,PHACTR2,RSBN1,TCF7L2,SYNCRIP,RIOK3,EIF2S1,PTP4A2,PDLIM5,RPS6KC1,BRWD3,ZAK,STK4 |
| 8.269e-03 | -4.80 | regulation of tumor necrosis factor-mediated signaling pathway | biological process | GO:0010803 | 49 | 13 | 16441 | 2138 |
PTPN2,ZNF675,RBCK1,CYLD,IKBKB,TNFRSF1A,RIPK1,GAS6,NOL3,HSPA1A,BIRC2,UBC,HSPA1B |
| 8.269e-03 | -4.80 | cellular modified amino acid biosynthetic process | biological process | GO:0042398 | 49 | 13 | 16441 | 2138 |
SEPHS2,GGT1,MTHFD2,GART,ATIC,PLOD1,MTHFD1L,ALDH18A1,CNDP2,GGT7,MTHFD2L,MAT2A,MTHFD1 |
| 8.269e-03 | -4.80 | protein monoubiquitination | biological process | GO:0006513 | 49 | 13 | 16441 | 2138 |
PAF1,RNF40,KLHL22,RAD18,WAC,CTR9,RNF2,BCOR,TRIM37,CDC73,RING1,NEDD4,UBE2E1 |
| 8.274e-03 | -4.79 | HDR through Single Strand Annealing (SSA) | REACTOME pathways | R-HSA-5685938 | 37 | 11 | 8202 | 1117 |
ABL1,EXO1,RFC4,RFC3,RBBP8,TOP3A,ATM,ATRIP,BRCA1,RMI1,RPA1 |
| 8.274e-03 | -4.79 | MLH1 (mutL homolog 1) | protein interactions | 4292 | 125 | 28 | 16036 | 2270 |
PMS1,WDR61,ACTG1,FANCD2,FAN1,PSMA1,PPP2R2A,APRT,BRCA1,EIF2A,TMSB4X,FLNB,UBC,EXO1,YLPM1,E2F4,MYC,MSH3,UBAP2L,ATM,ABCC3,PPP3CC,RAPGEFL1,ANXA2,MSH4,TXN2,AMOT,SPTAN1 |
| 8.285e-03 | -4.79 | TCANNTGAY_V$SREBP1_01 | MSigDB lists | TCANNTGAY_V$SREBP1_01 | 453 | 76 | 17758 | 2279 |
MAP2K5,ATP6V1A,ATRX,RBFOX2,DDR2,TM4SF19,AARS,GIT2,VPS18,ZNF827,SRSF2,KDM2A,ATG3,JOSD1,CHD2,TMEM136,AHCYL1,FUT11,MOSPD1,KDM3B,SLC3A2,AKAP12,S100A16,CAMK2D,SLC30A3,TP53BP1,HSPBAP1,NSMCE2,DLX2,EME1,MID1,ATXN7L2,KLHL24,ESCO1,BRAF,SEC24D,SUPT6H,ITPRIP,ANKRD17,PAX2,RTN4,FOXP1,GIGYF2,CHN1,PRKCE,FAM50A,COMMD9,DCTN4,STC2,GTF2H1,ATP6V0D1,MSI2,BDNF,APEX1,STAG1,ZFYVE1,SETD2,TOP3A,MARS,ARHGEF12,R3HDM2,GPNMB,MBNL2,MMAA,VAC14,NAP1L5,RPL28,HIF1A,ZBTB8OS,HK2,EIF2S1,MBD6,PSAP,NAPA,RABEP1,DDIT3 |
| 8.287e-03 | -4.79 | FORTSCHEGGER_PHF8_TARGETS_UP | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_UP | 252 | 46 | 17758 | 2279 |
PTP4A1,ZNF76,ID1,RBM33,PDK4,ZNF280C,ENAH,CHAC1,PHGDH,TGFBR2,BMP6,GABPB2,PABPC4,MAN1A1,DDIT4,FKBP1A,PTPN2,RNF141,ASNS,SLC7A11,NSRP1,STC2,PCK2,HN1,ATF4,SESN2,ALDH1L2,TFPI,NLN,MRRF,SERP1,RAB10,LYRM7,HERPUD1,NR2F1,PYCR1,DDX3X,CDH24,MTHFD2,SSU72,SYNCRIP,SET,MBTD1,SLC16A1,CNOT6,FNBP1L |
| 8.290e-03 | -4.79 | transcription regulatory region DNA binding | molecular function | GO:0044212 | 791 | 127 | 16491 | 2164 |
TCF12,ZNF516,NPAS2,SMARCA4,PBX1,BCOR,HLTF,FOSL2,GABPB2,KDM1A,SMARCB1,CHD7,RRN3,NRF1,SREBF2,ZFHX3,IKZF5,RELB,ZEB1,ZNF148,CHD2,ZNF85,ZNF460,ETV1,KMT2A,LONP1,CARM1,DDN,AEBP2,KMT2D,ATF4,ZNF195,PPARG,ZNF680,BAZ2A,NR6A1,ZNF480,NFIA,CUX1,RFX2,POU2F1,MEF2D,BRCA1,ZSCAN2,SOX4,SNCA,GZF1,BATF3,VDR,TAF2,SMAD3,UBTF,SKIL,MSX2,TCF7L1,SMARCC1,GATA6,IKZF4,CCNT1,SIX5,CC2D1B,PER1,KLF4,E2F4,ARNTL,CEBPZ,RUNX1,DLX2,ZC3H8,ZBTB11,MEF2C,HMGA2,EGR1,TAF1,RFX1,PAX2,TCF3,DPF2,AGO2,SMAD7,NFX1,HES6,BARX2,BHLHE40,ZNF691,FOXO3,MLX,ZNF586,ZNF561,SUV39H2,MBD2,MYC,YBX3,PRMT5,NRIP1,DMRT1,SOX6,MYB,TOP1,ARNTL2,ZNF675,GATAD2B,MSX1,RREB1,PAXBP1,ZNF821,PSPC1,ARID5B,PRDM1,MEN1,ONECUT2,FOXC1,TCF7L2,ZNF708,NSD1,MYBBP1A,GADD45A,ARID3B,CDK9,TBX3,PURB,ZNF430,RBPJ,NCOR1,TBL1X,SMYD3,DDIT3 |
| 8.310e-03 | -4.79 | IWANAGA_CARCINOGENESIS_BY_KRAS_DN | MSigDB lists | IWANAGA_CARCINOGENESIS_BY_KRAS_DN | 119 | 25 | 17758 | 2279 |
TNNC1,ARNTL2,PIGN,LETM1,SKAP2,GTF2IRD1,PITPNB,SAFB2,PLXNB1,RERE,TERF2IP,PRKCE,GRIK4,ETFDH,CDC16,HNRNPR,NSMCE2,KLF4,CFD,INTS12,MAP3K14,ITGB4,NR2F2,TRIM14,TMEM200A |
| 8.334e-03 | -4.79 | CSR_LATE_UP.V1_DN | MSigDB lists | CSR_LATE_UP.V1_DN | 156 | 31 | 17758 | 2279 |
FADS1,TRERF1,CDC42EP2,ELOVL6,ANKRD33B,TNXB,TRIM22,GAS6,C1orf52,LPAR3,DDX60L,ECH1,LPIN1,EXOC6,MAN1A1,DYRK1B,LSS,SAMD5,IDI1,INSIG1,FGGY,FDPS,NBEA,DPP4,ME1,DHCR7,IGBP1,PLEKHG4,SLC25A1,FDFT1,HMGCR |
| 8.351e-03 | -4.79 | UBE3A (ubiquitin protein ligase E3A) | protein interactions | 7337 | 142 | 31 | 16036 | 2270 |
HERC2,METTL1,ARNTL2,MYCBP2,ATG9A,UBXN1,ASAP3,MYH9,SUMO3,C11orf49,BRCA1,RMI1,UBC,UBE2E1,ANXA1,SRPRB,SACS,P3H1,UBE3A,UCHL5,CEBPZ,ARNTL,TNPO3,TTC3,RNF2,ARC,PSAP,ANXA2,LRSAM1,IPO11,LPP |
| 8.351e-03 | -4.79 | TADA2A (transcriptional adaptor 2A) | protein interactions | 6871 | 142 | 31 | 16036 | 2270 |
EIF3C,LUZP1,PRPF31,PRKAB2,PSPC1,TRA2A,TCF3,PLRG1,MED27,HSPA5,KLC4,SF3A3,FARS2,MED18,MED16,POLR2A,EIF3H,TADA3,DDX3X,ATXN7,SNW1,LUC7L3,MYC,MED15,MED20,SRRM2,YEATS2,DOCK6,HNRNPM,PRPF19,EMSY |
| 8.360e-03 | -4.78 | Transcriptional activation of mitochondrial biogenesis | REACTOME pathways | R-HSA-2151201 | 42 | 12 | 8202 | 1117 |
NRF1,CHD9,C10orf2,PPARGC1B,SMARCD3,TBL1X,MEF2D,NCOR1,SSBP1,POLG2,CARM1,MEF2C |
| 8.367e-03 | -4.78 | GGGCATT,MIR-365 | MSigDB lists | GGGCATT,MIR-365 | 107 | 23 | 17758 | 2279 |
SSH2,EIF4E3,ANKRD17,SESTD1,PAX2,ARRDC3,RAPGEF4,ADAMTS6,WDR37,MAPK1IP1L,SATB2,PRDM1,DCUN1D5,KCNH2,SYNJ1,YTHDF2,ANKRD11,C16orf58,ARHGAP12,ETV1,C18orf25,ANKS1A,HMGCR |
| 8.370e-03 | -4.78 | PLEC (plectin) | protein interactions | 5339 | 76 | 19 | 16036 | 2270 |
COL17A1,CUL7,JUP,FN1,ACTG1,TRA2A,SIRT7,VIM,GBF1,ISG15,FMNL1,CDK9,SOCS6,USP20,ITGB4,SRRM2,BMI1,RABEP1,SPTAN1 |
| 8.370e-03 | -4.78 | TTC1 (tetratricopeptide repeat domain 1) | protein interactions | 7265 | 76 | 19 | 16036 | 2270 |
SEC24A,CARS,SARS,GARS,TUBA1A,PSAT1,TRIP6,HARS,EIF3J,XPO5,UBXN1,XPO7,HSPA1A,SH3GL1,SRPRB,SREBF2,VAPB,ZRANB2,AHCYL1 |
| 8.370e-03 | -4.78 | TCERG1 (transcription elongation regulator 1) | protein interactions | 10915 | 76 | 19 | 16036 | 2270 |
EVL,BRD4,FN1,PSPC1,HSPA5,TPM4,SF3A3,PHGDH,HSPA1A,POLR2A,HSPA1B,CHAF1A,RPA1,CHD3,FMNL1,CBWD1,PSAP,HNRNPM,SF3A1 |
| 8.377e-03 | -4.78 | RNA Polymerase II Transcription | REACTOME pathways | R-HSA-73857 | 107 | 24 | 8202 | 1117 |
GTF2H3,GTF2H2C,RNMT,TAF1,AK6,TCEB3,NELFA,SUPT5H,POLR2A,TAF9B,TAF2,ELL,SUPT4H1,SRSF2,GTF2A1,TAF3,CCNT1,CDK9,TAF4,GTF2H1,NCBP2,TAF12,CPSF3,LSM10 |
| 8.378e-03 | -4.78 | organ regeneration | biological process | GO:0031100 | 71 | 17 | 16441 | 2138 |
PPARG,PPAT,CDK4,POU2F1,C5AR1,CAV1,GAS6,LPIN1,CAD,SOCS1,SHC1,ATIC,UPF2,HMBS,PRMT5,PRPS1,ANGPT2 |
| 8.378e-03 | -4.78 | fatty acid oxidation | biological process | GO:0019395 | 71 | 17 | 16441 | 2138 |
MCEE,ACADS,SESN2,PPARG,PCCA,CPT1A,ACOXL,MMAA,ECH1,ETFB,PEX7,ETFDH,DECR1,ACOX1,BDH2,PEX13,CPT1C |
| 8.396e-03 | -4.78 | GSE17721_CTRL_VS_POLYIC_1H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_1H_BMDM_DN | 194 | 37 | 17758 | 2279 |
PPDPF,CDCP1,ASH1L,LUZP1,ACTG1,CA11,SLC2A1,OPHN1,PDE4B,JMJD6,FOXP1,SLC25A20,DCTN4,KDM5C,LYST,TBC1D8,NAA38,GARS,ZNF124,LIMA1,RB1CC1,HSPA5,ATF7IP2,ATXN1,TMEM123,SEMA3F,KRTCAP2,C1orf174,TJAP1,ZFP62,FSCN1,CEBPZ,RAD51B,CDKAL1,EIF2S1,CATSPERG,CORO2B |
| 8.413e-03 | -4.78 | PID_ATM_PATHWAY | MSigDB lists | PID_ATM_PATHWAY | 34 | 10 | 17758 | 2279 |
ABL1,RBBP8,TP53BP1,FANCD2,H2AFX,TOP3A,ATM,BRCA1,XRCC4,TERF2 |
| 8.429e-03 | -4.78 | serine family amino acid biosynthetic process | biological process | GO:0009070 | 15 | 6 | 16441 | 2138 |
SEPHS2,GGT1,SHMT2,PSAT1,PHGDH,MTHFD1 |
| 8.429e-03 | -4.78 | mitochondrial fusion | biological process | GO:0008053 | 15 | 6 | 16441 | 2138 |
GDAP1,FIS1,OPA1,STOML2,MFN2,MIEF1 |
| 8.429e-03 | -4.78 | craniofacial suture morphogenesis | biological process | GO:0097094 | 15 | 6 | 16441 | 2138 |
MSX2,INSIG2,BMP4,INSIG1,MMP16,MMP14 |
| 8.430e-03 | -4.78 | purine nucleoside metabolic process | biological process | GO:0042278 | 275 | 50 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,MRI1,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,AHCYL2,NDUFB3,AMPD3,NDUFV1,ENTPD5,ATP5G2,PPCDC,MYH3,NDUFA6,AHCYL1,FXN,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,LDHA,SULT4A1,DLG4,ATP6V0A1,ADSL,IMPDH2,MAT2A,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,NME7,COQ9,PEMT,HK2,SURF1,NDUFS5,BPNT1,MACROD1,ADK |
| 8.441e-03 | -4.77 | GSE29618_BCELL_VS_PDC_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_UP | 175 | 34 | 17758 | 2279 |
PTP4A1,MYCBP2,IFT57,EGR1,FOXO1,ST6GAL1,UBXN1,TRIO,ZFP36L1,CHD7,SIPA1L3,PMAIP1,MYC,TANK,SHMT2,NOC3L,KIAA0922,PLEKHA2,LYST,NT5E,EVL,TUBA1A,PDK1,ARID5B,PTPN12,SLC35F2,PWP1,PDLIM1,HIF1A,HK2,TBL1X,SYNPO,DDIT3,RAB30 |
| 8.441e-03 | -4.77 | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP | 175 | 34 | 17758 | 2279 |
VIPR1,KCTD7,SSH2,TMEM63C,TRAK1,DLGAP4,SMAD7,MYH9,C1orf52,MRPS30,RAP1A,IKZF5,GLTP,JOSD1,CCDC88C,PFKFB4,TTLL5,SESN2,FBXW4,TSPYL4,PSPC1,TLE3,IDH3G,RAP1B,MEF2D,PTK2,GZF1,TAF9B,ZNF160,SVIL,SGSM2,PURB,SMYD3,ZNF598 |
| 8.442e-03 | -4.77 | SRSF5 (serine/arginine-rich splicing factor 5) | protein interactions | 6430 | 103 | 24 | 16036 | 2270 |
TNK2,SART1,SNU13,OLFM2,UTP14A,TRA2A,SIRT7,MYH9,IKBIP,PHGDH,SON,RHOT2,DDX3X,TMCO1,HNRNPR,COPS5,SURF1,PSAP,SRRM2,HNRNPM,TIMM50,SRPK2,PRPF19,SF3A1 |
| 8.442e-03 | -4.77 | KAT2A (K(lysine) acetyltransferase 2A) | protein interactions | 2648 | 103 | 24 | 16036 | 2270 |
CUL4A,PPARG,TCF3,MAPK8IP3,LDHA,PBX1,WDHD1,SIRT2,MED16,TAF9B,SMAD3,TADA3,ATXN7,TRRAP,TAF3,MYC,E2F4,TAF4,CUL2,H2AFX,ZNF148,RBPJ,YEATS2,MYB |
| 8.442e-03 | -4.77 | HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) | protein interactions | 9987 | 103 | 24 | 16036 | 2270 |
CUL7,CUL4A,FN1,CSNK2A1,HNRNPA3,YARS2,PABPC4,RPA1,DDX3X,SRSF2,AHNAK,HNRNPR,LSM14A,ATIC,HNRNPH3,COPS5,CUL2,UBAP2L,H2AFX,RNF2,RMDN3,FUS,COPS6,HNRNPM |
| 8.514e-03 | -4.77 | RNA Polymerase III Transcription Termination | REACTOME pathways | R-HSA-73980 | 23 | 8 | 8202 | 1117 |
POLR3D,POLR3E,NFIA,CRCP,POLR3B,POLR1C,POLR3A,POLR3G |
| 8.514e-03 | -4.77 | Cholesterol biosynthesis | REACTOME pathways | R-HSA-191273 | 23 | 8 | 8202 | 1117 |
LSS,IDI1,MVK,FDPS,SQLE,DHCR7,HMGCR,FDFT1 |
| 8.526e-03 | -4.76 | LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | MSigDB lists | LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | 207 | 39 | 17758 | 2279 |
SLC12A7,NDUFB5,NAT10,PBX1,MYNN,OPA1,POGZ,SLC39A1,KDM2A,SHC1,PI4KB,MYC,MET,CD44,LPCAT1,ZNF3,CAV2,METTL1,NAA38,AP4S1,TSTA3,CDK4,ABCF2,MANBAL,PNN,KCNH2,TARS,MRPL36,BAZ1A,CAT,CUL2,TECPR2,MBD6,COPS6,DHCR7,DDX10,MIPOL1,PARD3,DDIT3 |
| 8.586e-03 | -4.76 | ALL1 (Leukemia, acute lymphocytic, susceptibility to, 1) | protein interactions | 100310785 | 18 | 7 | 16036 | 2270 |
TASP1,RAN,SMARCC1,CHD3,TAF1,SMARCB1,SAP30 |
| 8.586e-03 | -4.76 | PALLD (palladin, cytoskeletal associated protein) | protein interactions | 23022 | 18 | 7 | 16036 | 2270 |
LIG4,SARS,NDUFV1,IGBP1,SIRT6,ACOX1,ISG15 |
| 8.586e-03 | -4.76 | OSBPL10 (oxysterol binding protein-like 10) | protein interactions | 114884 | 18 | 7 | 16036 | 2270 |
VAPB,PGAM5,USP11,SRRM2,CLINT1,OSBPL9,ZC3H18 |
| 8.586e-03 | -4.76 | ZC3H4 (zinc finger CCCH-type containing 4) | protein interactions | 23211 | 18 | 7 | 16036 | 2270 |
WIZ,DYNC1H1,PAF1,DBN1,RNF2,BMI1,FLNB |
| 8.586e-03 | -4.76 | UTP4 (UTP4 small subunit (SSU) processome component) | protein interactions | 84916 | 18 | 7 | 16036 | 2270 |
RNF2,BRCA1,FBL,GLTSCR2,SIRT7,ISG15,UTP15 |
| 8.586e-03 | -4.76 | TTC37 (tetratricopeptide repeat domain 37) | protein interactions | 9652 | 18 | 7 | 16036 | 2270 |
SKIV2L,PAF1,SNW1,EXOSC4,AP1B1,TRIP13,SIRT7 |
| 8.586e-03 | -4.76 | CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) | protein interactions | 1030 | 18 | 7 | 16036 | 2270 |
ZBTB17,CEP126,IKBKAP,CDK6,PYCRL,CDK4,ARPC3 |
| 8.587e-03 | -4.76 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | 352 | 61 | 17758 | 2279 |
TCF12,BCCIP,AK2,MCM6,EGR1,PRDX6,ATRX,OLA1,NDUFB5,RSL1D1,RCAN1,SSBP2,BHLHE40,BZW2,HDDC2,PRKCH,ATIC,MCM5,CFDP1,SHMT2,SSBP1,ANP32B,FBL,AHCYL1,PPA1,SERBP1,MTHFD1,MYB,RFC4,WDR61,APEX1,CDK4,PCCA,KIF15,LDHA,PCMT1,PSMG1,MARCKSL1,ADSL,AKAP12,IMPDH2,MCM2,EHBP1,CLNS1A,PGD,RPA1,GNAI1,STOML2,CAT,EPRS,HPRT1,PXDN,POLE2,PDLIM1,TRMT5,KLF4,SET,COPS6,BLMH,GCSH,MEF2C |
| 8.592e-03 | -4.76 | Height(PMID:18391950) | GWAS genes | Height(PMID:18391950) | 15 | 7 | 2389 | 419 |
WDR60,HMGA2,LIN28B,UQCC1,ADGRG6,CDK6,DOT1L |
| 8.620e-03 | -4.75 | HNRNPF (heterogeneous nuclear ribonucleoprotein F) | protein interactions | 3185 | 148 | 32 | 16036 | 2270 |
USP7,CUL7,CUL4A,FN1,RBFOX2,ACTR3,SIRT7,MBNL1,HNRNPA3,MYC,RDX,SRRM2,HNRNPM,CLK2,PRAME,HARS,HSPA5,ANKMY2,RHOT2,POLR2A,UBC,RPA1,TOE1,RANBP2,EIF4ENIF1,HNRNPR,COPS5,HNRNPH3,CUL2,NCBP2,FUS,COPS6 |
| 8.656e-03 | -4.75 | RSRP1 (arginine/serine-rich protein 1) | protein interactions | 57035 | 14 | 6 | 16036 | 2270 |
FAM192A,TNPO3,SHMT2,PRMT5,CLK2,SRPK2 |
| 8.665e-03 | -4.75 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN | 188 | 36 | 17758 | 2279 |
SLC12A7,SRM,MCM6,SHQ1,B4GALT5,RNASEH2B,PABPC4,FRRS1,NOP56,ZNF239,CAD,CD96,ZNF358,NEK6,ATIC,TIMELESS,PRADC1,PRF1,PPA1,TRIM14,ACSL5,RFC4,ANAPC13,ELP3,MANBAL,MTHFD1L,EIF2A,MEN1,PEAK1,BAZ1A,AHNAK,PMEPA1,DPP4,UMPS,ANXA2,SCARB1 |
| 8.665e-03 | -4.75 | GSE14308_TH1_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_TH1_VS_INDUCED_TREG_DN | 188 | 36 | 17758 | 2279 |
LUZP1,TRIP6,LIAS,AP1B1,RPAIN,FARSA,KCTD11,CNIH3,ATP5G2,ERI1,COPS3,BUD31,C16orf58,WDR60,HIBCH,LONP1,NAA38,ATF4,RBCK1,WDR61,SIGMAR1,USP49,PPP1R21,ZDHHC14,TRIM37,EHBP1,VAC14,PES1,INF2,FSCN1,GLG1,WDR7,ARC,PDSS2,BAG1,MORC2 |
| 8.666e-03 | -4.75 | embryonic viscerocranium morphogenesis | biological process | GO:0048703 | 11 | 5 | 16441 | 2138 |
CHST11,MTHFD1L,RDH10,MEF2C,MTHFD1 |
| 8.666e-03 | -4.75 | ribonucleoprotein complex disassembly | biological process | GO:0032988 | 11 | 5 | 16441 | 2138 |
MRRF,MTIF2,TFIP11,GFM2,DENR |
| 8.678e-03 | -4.75 | BROWNE_HCMV_INFECTION_18HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_DN | 169 | 33 | 17758 | 2279 |
MAP2K5,ID1,CDC42EP2,BTBD2,RFX1,TRAK1,LAGE3,APRT,GAS6,DENND3,PLXNB1,DST,PTRF,SOCS1,YLPM1,MYC,ARHGAP1,GSTA4,CD44,CCDC88C,OGG1,CARM1,SNX29,FADS1,TEAD1,TPM4,CTIF,IRS1,VDR,INSIG1,VCAN,CCDC85B,SURF1 |
| 8.678e-03 | -4.75 | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP | MSigDB lists | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP | 169 | 33 | 17758 | 2279 |
MINK1,STX8,BIRC6,PAFAH1B1,MRPL10,MKS1,JMJD6,CCDC47,MAP2K3,SRSF2,ANAPC11,FTSJ3,CTC1,HN1,MSI2,BRCA1,POLG2,RAB10,DHX57,PYCR1,EPN2,SUPT4H1,TOM1L2,SRP68,LUC7L3,SLC25A19,PTRH2,RPS6KB1,ABCC3,EME1,NCOR1,ZNF18,MAP2K4 |
| 8.689e-03 | -4.75 | regulation of cellular response to transforming growth factor beta stimulus | biological process | GO:1903844 | 106 | 23 | 16441 | 2138 |
CHST11,PRDM16,HSPA5,SMAD7,NREP,MEN1,TGFBR2,ONECUT2,UBC,SKI,SKIL,SMAD3,SNW1,PMEPA1,LEMD3,HIPK2,UCHL5,GLG1,RNF111,ZEB1,PEG10,CAV2,USP15 |
| 8.689e-03 | -4.75 | cytoskeleton-dependent intracellular transport | biological process | GO:0030705 | 106 | 23 | 16441 | 2138 |
IFT57,TUBA1A,MYO10,PAFAH1B1,IFT43,KIF5A,KIF5C,MAP1S,OPA1,RHOT2,BLOC1S4,BLOC1S2,ARHGAP21,IFT81,BICD1,NME7,WDR35,HIF1A,DTNBP1,IFT140,DYNC2H1,KIF1B,MAPT |
| 8.689e-03 | -4.75 | regulation of transforming growth factor beta receptor signaling pathway | biological process | GO:0017015 | 106 | 23 | 16441 | 2138 |
CHST11,PRDM16,HSPA5,SMAD7,NREP,MEN1,TGFBR2,ONECUT2,UBC,SKI,SKIL,SMAD3,SNW1,PMEPA1,LEMD3,HIPK2,UCHL5,GLG1,RNF111,ZEB1,PEG10,CAV2,USP15 |
| 8.709e-03 | -4.74 | nuclear envelope disassembly | biological process | GO:0051081 | 44 | 12 | 16441 | 2138 |
RANBP2,NEK6,PAFAH1B1,NUP133,BANF1,NUP43,PRKCA,NUP160,NUP214,POM121,SEH1L,LPIN1 |
| 8.709e-03 | -4.74 | membrane disassembly | biological process | GO:0030397 | 44 | 12 | 16441 | 2138 |
RANBP2,NEK6,PAFAH1B1,NUP133,BANF1,NUP43,PRKCA,NUP160,NUP214,POM121,SEH1L,LPIN1 |
| 8.716e-03 | -4.74 | regulation of protein ubiquitination | biological process | GO:0031396 | 256 | 47 | 16441 | 2138 |
UBXN1,SMAD7,RCHY1,BIRC2,PSMF1,UBR5,HSPA1A,MAD2L2,KDM1A,RNF40,ABL1,FKBP1A,ANAPC1,UBE3A,ANAPC11,ANAPC10,MAD1L1,RNF111,CTR9,PRMT3,ARRDC3,HSPA5,TEX14,NXN,SUMO3,PSMA1,BRCA1,CAV1,DCUN1D5,PTK2,SOX4,ARRDC4,HERPUD1,UBC,UBE2E1,ISG15,HSPA1B,TRIB3,KLHL22,CDC16,CDK9,DNAJA3,ATG7,ATM,CLU,BMI1,ANAPC4 |
| 8.776e-03 | -4.74 | WDR77 (WD repeat domain 77) | protein interactions | 79084 | 87 | 21 | 16036 | 2270 |
APEX1,CDK4,SMARCA4,PPIL1,SAP30BP,USP46,HIST2H2AB,UBC,CLNS1A,TOE1,CTNNBL1,COPS4,MBD2,MYC,CUL2,PQBP1,RIOK1,PRMT5,AGO3,HNRNPM,SF3A1 |
| 8.815e-03 | -4.73 | protein C-terminus binding | molecular function | GO:0008022 | 178 | 35 | 16491 | 2164 |
USP7,MIF4GD,ID1,VTA1,AGO2,BLOC1S2,DST,ABL1,ECM1,SREBF2,ATXN2,SDCBP2,CORO1A,CEP135,PXK,PABPC1,TERF2,CDC37,ATF4,TFCP2,FOXN3,DLG4,ATXN1,LIG4,EFHC1,VIM,RABAC1,PEX1,KPNA3,ARL6IP5,PQBP1,HIC2,TBL1X,MAGI1,XRCC4 |
| 8.823e-03 | -4.73 | human chr1p36 | chromosome location | human chr1p36 | 31 | 8 | 26250 | 2590 |
LUZP1,SPEN,EYA3,ZNF436,CLCN6,ERRFI1,UTS2,MAD2L2 |
| 8.830e-03 | -4.73 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 691 | 110 | 17775 | 2278 |
PHF3,CELSR3,NF1,PDK4,DDR2,TRPM6,CSNK2A1,SMARCA4,RIPK1,RNF43,STK33,PRKCA,MAP2K3,RIOK2,ABL2,PRKD3,NEK6,RPS6KL1,IKBKB,ADCK4,MET,CDK12,CDK6,PRKACB,SRPK2,SLC38A6,TNK2,NRAS,BRD4,PDK1,NR6A1,PTPRM,CDK4,KSR2,MARCH6,BRCA1,SGK2,KMT2C,SON,STK10,FGFR1,SPOP,DYRK1B,PLIN2,SMAD3,CAMK2D,BRCA2,TRRAP,ELP2,CC2D1B,HIPK2,CSMD3,RPS6KB1,RIOK1,LAMA5,YEATS2,SMG1,SLC12A7,TNIK,BCKDK,BRAF,ZHX3,MAP3K13,CLK1,TAF1,CAMK1,TRIO,MRI1,PIK3R4,MED13L,MLH1,TGFBR2,CSNK1A1,CHD5,ARID1B,BZW2,ABL1,PRKCE,PRKCH,UBE3A,TANK,MAP3K12,RPS6KB2,CLK2,TOP1,DIS3L2,DDHD1,SIK3,CAMKK2,TEX14,OBSCN,R3HDM2,ARID1A,EIF5B,OXSR1,RETSAT,TRIB3,LRP1B,DSC2,GADD45A,ZZEF1,RIOK3,ATM,NR2F2,RPS6KC1,TBCK,ZAK,MAP2K4,PDE9A,STK4 |
| 8.840e-03 | -4.73 | BHAT_ESR1_TARGETS_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_DN | 78 | 18 | 17758 | 2279 |
EFNB2,CGN,INSIG2,PDK4,ARID5B,LETMD1,GTF2IRD1,MEF2D,SEMA3E,ATP8B2,TGFB2,MKX,ALAD,ZKSCAN1,GALNT10,NRP1,CDK6,PTPN14 |
| 8.866e-03 | -4.73 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 138 | 28 | 17758 | 2279 |
INSIG2,PDK1,EGR1,KIF5A,ALDH1L2,JMJD1C,SLC2A1,JMJD6,RCAN1,PALLD,KLF6,RPS6KA5,ANGPTL4,GZF1,RARS,KCTD11,JAG1,ZNF330,KLF4,ARL6IP5,HK2,CSRNP1,XPNPEP1,ANXA2,RBPJ,CD44,ERRFI1,RPS6KC1 |
| 8.873e-03 | -4.72 | MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_DN | MSigDB lists | MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_DN | 50 | 13 | 17758 | 2279 |
PAF1,PCGF3,ADNP,TAF3,TCF3,RNF138,GTF2IRD1,GAS6,IGF2BP1,MET,TSEN2,LRRC37A,MTR |
| 8.873e-03 | -4.72 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | 50 | 13 | 17758 | 2279 |
SRM,CARS,SLC3A2,GARS,ASNS,ATF4,SRSF2,MYC,PPIL2,YARS,AARS,SERBP1,TIMM44 |
| 8.873e-03 | -4.72 | NUCLEOBASENUCLEOSIDE_AND_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | NUCLEOBASENUCLEOSIDE_AND_NUCLEOTIDE_METABOLIC_PROCESS | 50 | 13 | 17758 | 2279 |
HPRT1,AMPD3,PPAT,OLA1,UMPS,NT5C,ME1,FHIT,CMPK1,NT5M,ADK,PRPS1,PGD |
| 8.873e-03 | -4.72 | REACTOME_CIRCADIAN_CLOCK | MSigDB lists | REACTOME_CIRCADIAN_CLOCK | 50 | 13 | 17758 | 2279 |
ARNTL2,NPAS2,HIF1A,PER1,ARNTL,SMARCD3,MEF2D,NCOR1,TBL1X,BHLHE40,CPT1A,NAMPT,MEF2C |
| 8.909e-03 | -4.72 | Basal transcription factors | KEGG pathways | hsa03022 | 45 | 12 | 6908 | 881 |
TAF2,GTF2H3,GTF2A1,TAF1,TAF3,GTF2H2C,TAF4,TBPL1,GTF2H1,GTF2IRD1,TAF12,TAF9B |
| 8.909e-03 | -4.72 | Basal transcription factors | KEGG pathways | ko03022 | 45 | 12 | 6908 | 881 |
TAF2,GTF2H3,GTF2A1,TAF3,GTF2H2C,TAF1,TAF4,TBPL1,GTF2IRD1,GTF2H1,TAF12,TAF9B |
| 8.911e-03 | -4.72 | PBRM1 (polybromo 1) | protein interactions | 55193 | 36 | 11 | 16036 | 2270 |
CHD7,DPF3,SMARCC1,ARID2,COPS3,SMARCAD1,SIRT7,ZNF512B,SMARCA4,ARID1A,SMARCB1 |
| 8.911e-03 | -4.72 | TCEANC (transcription elongation factor A (SII) N-terminal and central domain containing) | protein interactions | 170082 | 36 | 11 | 16036 | 2270 |
HMBOX1,CSRNP1,CCDC85B,VPS52,ATXN1,BRCA1,PNMA1,MID1,VAC14,NEDD4,RAD54B |
| 8.911e-03 | -4.72 | EIF1B (eukaryotic translation initiation factor 1B) | protein interactions | 10289 | 36 | 11 | 16036 | 2270 |
HPRT1,TSR1,RAB7A,ACTR3,RPS29,PCMT1,EIF2S1,ATXN1,SHMT2,YARS,EIF3H |
| 8.917e-03 | -4.72 | cellular macromolecular complex assembly | biological process | GO:0034622 | 647 | 105 | 16441 | 2138 |
VMA21,IMMP2L,SART1,CHMP2A,EIF3C,UBN1,ATRX,AARS2,COBLL1,COA1,COX10,SYNJ1,SBDS,EDC3,DENR,BLOC1S2,NUBPL,ZNHIT6,XRCC2,CCDC40,LONP1,SRPK2,PRPF19,SF3A1,PTBP2,EIF3J,PREX1,PSMG1,ATP6V0A1,CAV1,HIST1H2BL,MCM2,FOXRED1,CLNS1A,EIF3H,CHAF1A,DDX3X,TAF2,ARMC4,SMAD3,HLA-DMA,GEMIN5,LSM14A,LUC7L3,H2AFX,RAD51B,CLU,MDN1,UQCC2,NOCT,AP2S1,TMEM33,TTN,SHQ1,TAF1,PRPF31,AGO2,SF3A3,RSF1,PRPF39,NOL3,DNAH1,MBNL1,POGZ,NDUFS7,MRPS11,FKBP1A,PSMG4,MBD2,ATXN2,HIST2H3D,CELF1,ANP32B,GEMIN4,TTC17,PRMT5,POLR1E,SCAF11,RANBP6,DDX28,PXN,TSPYL4,BCS1L,BMS1,EIF2A,SNAP25,HIST1H4J,PTK2,UBE2K,CENPP,NAP1L5,DYNC1H1,TSR1,BICD1,SNAP23,SET,SURF1,NCBP2,NDUFAF5,NDUFS5,UQCC1,SMYD3,AGO3,IPO4,KAT6A |
| 8.928e-03 | -4.72 | nuclear pore | cellular component | GO:0005643 | 73 | 17 | 17570 | 2233 |
DDX19A,PIK3R4,RANGAP1,NUP43,XPO7,NUP160,NUP214,POM121,RANBP2,KPNA1,KPNA3,NUP133,MAD1L1,RAN,SEH1L,IPO4,TMEM33 |
| 8.928e-03 | -4.72 | cellular localization | biological process | GO:0051641 | 2209 | 323 | 16441 | 2138 |
THOC5,PRKAB2,DDX19A,PLRG1,ENAH,NBEAL1,NUP160,SYNJ1,TOM1L1,EXOC1,RPS16,S100A10,PMAIP1,NSRP1,SYN2,ATP5G2,AP1M1,VPS52,HRG,SEH1L,GDAP1,NRAS,ATG9A,WLS,EXOC6B,AP4B1,CUX1,AKAP12,ZDHHC14,TMSB4X,STOML2,RBSN,BRCA2,CFD,VPS13D,FIS1,NRP1,NMD3,BANP,HERC2,IFT57,CELSR1,JUP,PRPF31,OPHN1,PIK3R4,SSR4,CLINT1,SLC1A1,ABCA7,PRKCE,TNPO3,TOMM34,TERF2,RABEPK,USE1,TIMM8B,BDNF,EXOSC2,SYNGAP1,MYO10,RAPGEF4,RYR2,SNAP25,EVI5,CPT1A,ATP9B,IRS1,SEC31A,DYNC1H1,VPS13C,KPNA1,KIDINS220,NME7,RPL28,NSF,HIF1A,SRP68,PEX13,SRP14,SGSM3,COG5,RAB11FIP4,SYT17,PAFAH1B1,ACTR3,VTI1A,MYH9,AP1B1,STAM,EEA1,FLNB,BLOC1S2,TERF2IP,ABCA12,ACD,VGF,DTNBP1,NBEA,ZC3H3,DENND1A,LYST,ASUN,DLG4,ERC1,VPS53,SNCA,PES1,ARHGAP21,DNAJA3,IFT140,ANXA2,LAMA5,MID1,RAB30,MAPT,TRIM36,BRAF,SCAMP3,TRAK1,SLC25A12,KIF5C,GAS6,MON2,MLH1,OPA1,TGFB2,NOL3,RSRC1,TMCO6,NEDD4,TAF3,UNC13A,NISCH,PMPCA,SDCBP2,UPF2,RDX,NLGN3,DYNC2H1,FGF9,CEP83,VPS37A,WDFY3,PACS1,PTK2,NOP58,UBC,ANXA1,ZDHHC11,STX1A,STX18,ATM,PSAP,GPAM,BMP4,DDIT3,IPO4,IMMP2L,BCAS4,NF1,KIF5A,SEC16A,SRPRB,ABL2,SRSF2,CNIH3,ATG3,NCKIPSD,RAN,TIMM50,PTPRK,CDC37,DBN1,ABCC4,MIOS,ANK2,ATOX1,HSPA5,NOL6,COL4A3BP,SUMO3,CAV1,FLVCR1,LSG1,MPC1,TIMM44,PEX1,KIF16B,GLS,PAF1,TOM1L2,CTAGE5,TNFRSF1A,SGSM2,CLU,C2CD5,CHMP4C,TTN,FN1,STX8,SEC24D,VTA1,STXBP6,NKD2,SMAD7,LAMTOR3,SMG7,XPO7,TIMM10,RHBDD1,SPIRE1,MLX,PPIL2,VAPB,RANBP6,TRAPPC9,IFT43,XPO5,OBSCN,MEX3B,TRAPPC6B,SYT1,BLOC1S4,HERPUD1,TCF7L2,EXOC6,SPAG9,BICD1,MYBBP1A,SNAP23,HK2,EXOC4,RRAGA,SIL1,BRSK2,NAPA,FNBP1L,TESC,CHMP2A,SNX27,ID1,OLFM2,RPS29,MYO7A,GPR143,TBCCD1,DENND3,PIBF1,RPAIN,GBF1,VPS18,NUP133,DNAJB6,ZDHHC6,IKBKB,SLC38A2,BCAP29,CORO1A,AHCYL1,CPSF3,VCL,TSPAN14,IPO11,AUP1,PRPF19,SEC24A,TUBA1A,RAB7A,ATXN1,TOR1AIP2,AKAP13,NUP214,RAB10,ATP5D,IFT81,RANBP2,KPNA3,COPS5,TIMM17A,NFASC,SEPT5,AP2S1,TSPAN5,SMG1,PARD3,TMEM33,UNC13D,TNIK,HM13,CAMK1,VPS45,MAP1S,FOXP1,ANKRD54,SLC25A20,PEX7,SEC24C,DCTN4,AMOT,MICAL3,PCSK6,MSX1,AP4S1,GPHN,FGF2,MON1A,SCFD2,FERMT2,PDE2A,RHOT2,RERE,MFN2,CACNB1,WDR35,TBX3,SET,VPS37B,NCBP2,RBPJ,NFKBIB,XPO6,KIF1B |
| 8.935e-03 | -4.72 | GSE22886_IL2_VS_IL15_STIM_NKCELL_DN | MSigDB lists | GSE22886_IL2_VS_IL15_STIM_NKCELL_DN | 182 | 35 | 17758 | 2279 |
SHQ1,PRPF31,CCDC47,PDCD5,NDUFS7,COMMD9,PUS3,RPS16,THADA,PAK1IP1,HIRIP3,VAPB,NDUFA6,TRMT12,LRP3,GNG5,NUDC,HN1,CRADD,MTIF2,PCMT1,FERMT2,CAV1,TRIB3,RPL28,DNAJC1,DCXR,NSF,CUL2,VPS37B,HIC2,RNF138,SLC4A7,RBP1,GALE |
| 8.950e-03 | -4.72 | POSITIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | MSigDB lists | POSITIVE_REGULATION_OF_CELLULAR_METABOLIC_PROCESS | 227 | 42 | 17758 | 2279 |
EGR1,TRERF1,CDC42EP2,FOXO1,NPAS2,PPARGC1B,TCF3,ATF7IP,RSF1,FOXO3,BMP6,MAP2K3,PSMG4,PHF5A,GTF2H1,NRIP1,SAMD4A,MAML3,KAT8,TNK2,CAMKK2,ATF4,KDM5A,SMARCD3,ARID1A,BRCA1,SUPT5H,SMAD3,DYRK1B,HPRT1,NSD1,SUPT4H1,SMARCC1,HIF1A,MKL2,ARNTL,ATG7,TNFRSF1A,RUNX1,BMP4,MAPT,KAT6A |
| 8.952e-03 | -4.72 | nucleocytoplasmic transport | biological process | GO:0006913 | 237 | 44 | 16441 | 2138 |
THOC5,CAMK1,DDX19A,SMG7,XPO7,TGFB2,NUP160,RSRC1,RPAIN,TMCO6,ANKRD54,MLX,SRSF2,NSRP1,NUP133,NCKIPSD,TNPO3,UPF2,RAN,AHCYL1,CPSF3,ZC3H3,IPO11,FGF9,RANBP6,XPO5,NOL6,ATXN1,AKAP13,NUP214,LSG1,NOP58,TCF7L2,RERE,RANBP2,KPNA1,MYBBP1A,KPNA3,SET,NCBP2,XPO6,NMD3,SMG1,IPO4 |
| 8.962e-03 | -4.71 | SIRT6 (sirtuin 6) | protein interactions | 51548 | 109 | 25 | 16036 | 2270 |
USP7,GATAD2B,TUBA1A,XPC,PARP2,ABCF2,USP10,WDHD1,VIM,IMPDH2,CCNDBP1,SUPT5H,PALLD,DSP,UBR5,HIST2H2AB,FLNB,RNF40,ANAPC1,SYNCRIP,CHD3,WAC,ANXA2,PRMT5,PDLIM5 |
| 9.003e-03 | -4.71 | KARS (lysyl-tRNA synthetase) | protein interactions | 3735 | 66 | 17 | 16036 | 2270 |
CARS,RANBP6,FN1,NARS,PAFAH1B1,SIRT7,JMJD6,MARS,VIM,CIAPIN1,EPRS,RARS,COPS5,MSH3,XPNPEP1,GEMIN4,NUDC |
| 9.009e-03 | -4.71 | protein binding involved in cell-cell adhesion | molecular function | GO:0098632 | 11 | 5 | 16491 | 2164 |
NFASC,DSC2,JUP,DSP,DSG2 |
| 9.009e-03 | -4.71 | ubiquitin-ubiquitin ligase activity | molecular function | GO:0034450 | 11 | 5 | 16491 | 2164 |
UBE2K,UBR5,PPIL2,ANAPC11,PRPF19 |
| 9.047e-03 | -4.71 | endoplasmic reticulum organization | biological process | GO:0007029 | 39 | 11 | 16441 | 2138 |
USE1,STX18,COL4A3BP,VAPB,TOR1AIP2,RTN4,CCDC47,SEC16A,CAV2,RAB10,TMEM33 |
| 9.047e-03 | -4.71 | DNA strand elongation | biological process | GO:0022616 | 39 | 11 | 16441 | 2138 |
RFC4,MCM6,RFC3,GINS3,PRIM2,APEX1,MCM5,POLA1,LIG4,MCM2,RPA1 |
| 9.053e-03 | -4.70 | ALKBH3 mediated reversal of alkylation damage | REACTOME pathways | R-HSA-112126 | 4 | 3 | 8202 | 1117 |
ASCC3,ASCC1,ALKBH3 |
| 9.076e-03 | -4.70 | GNF2_RAN | MSigDB lists | GNF2_RAN | 84 | 19 | 17758 | 2279 |
RFC4,RFC3,GNL3,OLA1,ADSL,ODC1,TARS,EPRS,MTHFD2,EIF2S2,NOP16,ATIC,BANF1,EIF2S1,RAN,SSBP1,PRMT5,YARS,SERBP1 |
| 9.098e-03 | -4.70 | 3',5'-cyclic-nucleotide phosphodiesterase activity | molecular function | GO:0004114 | 24 | 8 | 16491 | 2164 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 9.115e-03 | -4.70 | GSE28237_EARLY_VS_LATE_GC_BCELL_UP | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_UP | 195 | 37 | 17758 | 2279 |
ARL15,XPO7,NOL3,KCNJ14,ZNF483,THADA,DNAJB6,PDE10A,DCTN4,VAPB,WDR60,SELT,RNF2,CALN1,HCFC2,MBTPS2,RTN4RL2,CHD9,COL5A2,MIOS,TEX19,ATP6V0A1,PPIP5K2,NOP58,NR2F1,ARMC3,ZC3H12A,HTR7,IFT81,IREB2,BAZ2B,HIC2,RAD51B,PRRT3,APAF1,FNBP1L,MMP16 |
| 9.115e-03 | -4.70 | GSE14308_INDUCED_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_INDUCED_VS_NATURAL_TREG_DN | 195 | 37 | 17758 | 2279 |
UNC13D,DNAJA4,FOXO1,PPARGC1B,SLK,DCP1B,DLGAP4,HES6,MON2,CCDC47,OPA1,RLF,GBF1,GIGYF2,PAIP2,PRKCH,PUS3,SEMA3D,SELT,SYNJ2,MEIS3,ZNF710,CCDC88C,LYST,FAM172A,RAP1B,PNN,PPIP5K2,ARRDC4,SLC26A11,STK10,ZNF708,ATXN7,STX1A,PSAP,BRD9,STK4 |
| 9.117e-03 | -4.70 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | GO:0042771 | 29 | 9 | 16441 | 2138 |
SNW1,BRCA2,PMAIP1,HIPK2,TMEM109,CDIP1,AEN,SHISA5,DDIT4 |
| 9.117e-03 | -4.70 | heme metabolic process | biological process | GO:0042168 | 29 | 9 | 16441 | 2138 |
ALAD,CPOX,UROD,BDH2,HMBS,HMOX2,FXN,COX10,TMEM14C |
| 9.142e-03 | -4.69 | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_UP | 157 | 31 | 17758 | 2279 |
SCAF11,SOBP,TNIK,RFC3,JUP,PPAT,ATRX,LIMA1,SLC25A12,TBCCD1,SMARCA4,SMG7,PHACTR2,ATF7IP,SPATS2L,TRIM22,OASL,DDX60,RSRC1,ISG15,SPOP,SRCAP,SYNCRIP,PPID,LPIN2,GLG1,C16orf58,UPF2,CDK12,TRIM14,SMG1 |
| 9.145e-03 | -4.69 | NEGATIVE_REGULATION_OF_TRANSCRIPTION_DNA_DEPENDENT | MSigDB lists | NEGATIVE_REGULATION_OF_TRANSCRIPTION_DNA_DEPENDENT | 126 | 26 | 17758 | 2279 |
ZNF254,KDM5B,ZHX3,NR6A1,FOXN3,ARID5B,CUX1,NFX1,HDAC8,ATF7IP,PRDM1,BCOR,RSF1,MEN1,SUPT5H,SMAD3,NSD1,SUPT4H1,VPS72,KLF4,JAZF1,TBX3,ZEB1,ZNF148,RBPJ,NRIP1 |
| 9.170e-03 | -4.69 | Beta-Casp | smart domains | SM01027 | 4 | 3 | 9131 | 1249 |
CPSF3,CPSF3L,INTS9 |
| 9.170e-03 | -4.69 | FYRC | smart domains | SM00542 | 4 | 3 | 9131 | 1249 |
KMT2D,KMT2C,KMT2A |
| 9.184e-03 | -4.69 | CELLULAR_COMPONENT_ASSEMBLY | MSigDB lists | CELLULAR_COMPONENT_ASSEMBLY | 293 | 52 | 17758 | 2279 |
TTN,EIF3C,CDC42EP2,PRPF31,TNXB,SF3A3,PBX1,ATF7IP,RSF1,IKBKAP,COX10,NDUFS7,PAIP2,PTRF,ATXN2,MED24,CELF1,CCDC88C,VCL,SNAPC5,SF3A1,SRPK2,SCAF11,PXN,LAMC1,SKAP2,SFSWAP,MTIF2,EIF3J,MED27,EIF4A2,BCS1L,DLG4,MED16,EIF2A,SYT1,EIF3H,CHAF1A,GEMIN5,SMAD3,TAF2,EPRS,HPRT1,KPNA3,CDK9,SET,SURF1,PEX13,NDUFS5,EIF2B3,AP2S1,PARD3 |
| 9.184e-03 | -4.69 | ROZANOV_MMP14_TARGETS_UP | MSigDB lists | ROZANOV_MMP14_TARGETS_UP | 260 | 47 | 17758 | 2279 |
SLC12A7,CDCP1,FN1,PRDX6,RBFOX2,ST6GAL1,NKD2,CSNK2A1,DNAJC22,KDM1A,DDIT4,DENR,FKBP1A,JAG1,ANXA7,PMAIP1,MMP14,TRIML2,NDRG4,PTGS1,SERPINH1,ALDH18A1,ERRFI1,PAQR6,LAMA4,SOBP,MSX1,PPARG,FOXN3,ATF7IP2,TTYH2,NXN,SNAP25,ARRDC4,HERPUD1,HLA-DMA,C20orf196,PXDN,LMBR1L,PDLIM1,HIF1A,RWDD2B,TAF12,TPM1,IFITM2,KIF1B,N4BP2L2 |
| 9.208e-03 | -4.69 | aspartate family amino acid metabolic process | biological process | GO:0009066 | 55 | 14 | 16441 | 2138 |
MSRA,SDSL,ASNS,MRI1,SLC25A21,PLOD1,PHYKPL,AHCYL1,MTHFD2L,PHGDH,DLST,MTR,AHCYL2,MTHFD1 |
| 9.214e-03 | -4.69 | regulation of action potential | biological process | GO:0098900 | 34 | 10 | 16441 | 2138 |
CAMK2D,DSC2,JUP,ANK2,NTSR1,DSG2,RYR2,CAV1,DSP,NOS1AP |
| 9.214e-03 | -4.69 | histone ubiquitination | biological process | GO:0016574 | 34 | 10 | 16441 | 2138 |
PAF1,RNF40,WAC,CTR9,RNF2,BCOR,TRIM37,CDC73,RING1,UBE2E1 |
| 9.214e-03 | -4.69 | face morphogenesis | biological process | GO:0060325 | 34 | 10 | 16441 | 2138 |
MSX1,ARID5B,MYH3,CSRNP1,ANKRD11,TGFB2,TCF7L2,SKI,DKK1,KAT6A |
| 9.214e-03 | -4.69 | transcription initiation from RNA polymerase I promoter | biological process | GO:0006361 | 34 | 10 | 16441 | 2138 |
UBTF,RRN3,GTF2H3,PTRF,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 9.228e-03 | -4.69 | NCSTN (nicastrin) | protein interactions | 23385 | 82 | 20 | 16036 | 2270 |
SART1,RFC4,UTP14A,KHDRBS1,TRA2A,DPF2,WDR18,ZC3H18,RSL1D1,PHGDH,NOP58,NOP56,SMARCB1,ABL1,MYBBP1A,BCAS2,NOP16,HNRNPR,FTSJ3,TOP1 |
| 9.228e-03 | -4.69 | MED26 (mediator complex subunit 26) | protein interactions | 9441 | 82 | 20 | 16036 | 2270 |
TAF1,MED27,TCEB3,MED13L,MED18,MED16,POLR2A,ZC3H13,TAF2,ELL,TRRAP,TAF3,CCNT1,CDK9,TAF4,MED15,MED24,ICE2,MED20,RBP1 |
| 9.228e-03 | -4.69 | BROWNE_HCMV_INFECTION_1HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_1HR_DN | 208 | 39 | 17758 | 2279 |
BCKDK,PAX2,PCSK7,JMJD6,SEC16A,ETFB,TMCO6,DDIT4,TOX4,PHKA1,CACNB2,CLCN6,MAD1L1,VAPB,ERI3,ZNF710,AMOT,TERF2,MYB,KAT8,PPARG,BCS1L,DLG4,ARHGEF12,EIF5B,DHX57,SPOP,RDH11,SKIL,ETFDH,SPAG9,HIPK2,E2F4,HIC2,TBXA2R,IQSEC2,TXN2,MMP16,MORC2 |
| 9.237e-03 | -4.68 | MODULE_97 | MSigDB lists | MODULE_97 | 90 | 20 | 17758 | 2279 |
WDR75,BRAF,NRAS,MIOS,DBF4,OPA1,RLF,SEC16A,PIBF1,STK10,DDX49,C1orf159,PMAIP1,INTS7,DNAJA3,SEC24C,AEN,NCOR1,NMD3,STK4 |
| 9.237e-03 | -4.68 | NIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER | MSigDB lists | NIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER | 90 | 20 | 17758 | 2279 |
EP400,ZCCHC14,PCNT,KCNQ3,FAM189B,MYO7A,CACNA1H,RADIL,FGFR1,CHD7,POP1,GRIN2C,NSMCE2,DNAH17,IKBKB,HOXA3,CSMD3,PUS1,ARC,VPS13B |
| 9.238e-03 | -4.68 | TP53BP1 (tumor protein p53 binding protein 1) | protein interactions | 7158 | 126 | 28 | 16036 | 2270 |
MCM6,PCNT,DPF2,SIRT7,CUX1,PCMT1,LIG4,BRCA1,KDM1A,VAC14,RPA1,ANAPC1,SUB1,KPNA1,CDC16,SPAG9,KPNA3,RAD18,CCNT1,COPS5,ANAPC10,H2AFX,ATM,SHMT2,POLR1C,ANAPC4,TMPO,NUDC |
| 9.261e-03 | -4.68 | ribonucleoside metabolic process | biological process | GO:0009119 | 296 | 53 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,MRI1,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,AHCYL2,NDUFB3,CAD,AMPD3,NDUFV1,ENTPD5,ATP5G2,PPCDC,MYH3,CMPK1,NDUFA6,AHCYL1,FXN,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,UPP1,LDHA,SULT4A1,DLG4,ATP6V0A1,ADSL,IMPDH2,MAT2A,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,NME7,PEMT,COQ9,HK2,SURF1,UMPS,NDUFS5,BPNT1,ADK |
| 9.262e-03 | -4.68 | cellular response to nutrient levels | biological process | GO:0031669 | 149 | 30 | 16441 | 2138 |
CYP24A1,FADS1,ATF4,FOXO1,MIOS,PPARG,UPP1,PDK4,HSPA5,SLC2A1,PIK3R4,ATG12,ATG2B,GAS6,CAV1,SIRT2,TCF7L2,WNT2B,VDR,NPRL2,MYBBP1A,ASNS,SREBF2,PMAIP1,ATG7,RRAGA,EIF2S1,TXN2,SEH1L,TNRC6A |
| 9.276e-03 | -4.68 | CTNNB1 (catenin (cadherin-associated protein), beta 1) | protein interactions | 1499 | 315 | 60 | 16036 | 2270 |
FBXO45,EP400,CUL4A,JUP,FOXO1,TCF3,SMAD7,MYO7A,CSNK2A1,SMARCA4,PRKCA,CSNK1A1,TGFBR2,FOXO3,CDC73,TADA3,ABL1,COPS3,IKBKB,FHIT,IGF2BP1,MET,KMT2A,VCL,AMOT,CDK6,SOX6,HNRNPM,SERBP1,CARM1,PTPRK,DSC3,IFRD1,KMT2D,TUBA1A,PPARG,RB1CC1,PTPRM,CAV1,BRCA1,ARHGAP32,MEN1,TCF7L2,ISG15,HSPA1B,DKK1,GEMIN5,SMAD3,RANBP2,CDH24,TCF7L1,TRRAP,HIF1A,FSCN1,COPS5,ACP1,FUS,TBL1X,MAGI1,PTPN14 |
| 9.291e-03 | -4.68 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 234 | 43 | 17758 | 2279 |
DNAJC2,JMJD6,TGFBR2,HSPA1A,PHLDA2,TTC1,RRN3,SLC7A11,DNAJB6,ME1,SYNJ2,MAP3K14,SERPINH1,CD44,FLNC,SLC38A6,IFRD1,SLC3A2,UPP1,C11orf80,IL6R,PALLD,KLF6,UBR4,HSPA1B,WARS,SKIL,DYNC1H1,SLC7A1,GLS,MSX2,GADD45A,GTF2A1,FAT1,AGTPBP1,ABHD3,ANXA2,CLU,KIF1B,C18orf25,DDIT3,N4BP2L2,SMG1 |
| 9.303e-03 | -4.68 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 784 | 123 | 17775 | 2278 |
CUL4A,NF1,PDK4,DDR2,TRPM6,CSNK2A1,SMARCA4,RIPK1,SPATS2,TTI1,STK33,PRKCA,LCLAT1,MAP2K3,RIOK2,SMARCB1,ABL2,ANAPC1,PRKD3,NEK6,RPS6KL1,IKBKB,ME1,ADCK4,MET,HRG,KMT2A,CDK12,CDK6,PRKACB,CEP128,SRPK2,TNK2,NRAS,BRD4,PDK1,NR6A1,SIRT6,CDK4,KSR2,DLG4,MCL1,VIM,PNN,BRCA1,SGK2,GSTCD,STK10,FGFR1,DOT1L,DYRK1B,SMAD3,CAMK2D,AHNAK,BRCA2,TRRAP,SUFU,CHD3,HIPK2,HOXA3,RPS6KB1,RIOK1,RUNX1,MUTYH,SMG1,TNIK,BCKDK,BRAF,TAF1,CLK1,MAP3K13,ITPRIP,CAMK1,C10orf2,CMTM8,TRIO,PIK3R4,ZFP36L1,CCDC7,MLH1,CSNK1A1,TGFBR2,ABL1,PRKCH,PRKCE,SCN1B,CEP290,MYC,UNC13A,CTR9,MAP3K12,RPS6KB2,CLK2,TOP1,SIK3,CAMKK2,TEX14,OBSCN,ARID1A,MEN1,TMEM187,PIK3CB,RERE,OXSR1,EPRS,TRIB3,NSD1,INF2,LRP1B,PALB2,CUL2,STX18,RIOK3,ATM,NCOR1,WDR33,SORCS2,RPS6KC1,TBCK,ZAK,MAP2K4,NIT1,STK4 |
| 9.303e-03 | -4.68 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 784 | 123 | 17775 | 2278 |
CUL4A,NF1,PDK4,DDR2,TRPM6,CSNK2A1,SMARCA4,RIPK1,SPATS2,TTI1,STK33,PRKCA,LCLAT1,MAP2K3,RIOK2,SMARCB1,ABL2,ANAPC1,PRKD3,NEK6,RPS6KL1,IKBKB,ME1,ADCK4,MET,HRG,KMT2A,CDK12,CDK6,PRKACB,CEP128,SRPK2,TNK2,NRAS,BRD4,PDK1,NR6A1,SIRT6,CDK4,KSR2,DLG4,MCL1,VIM,PNN,BRCA1,SGK2,GSTCD,STK10,FGFR1,DOT1L,DYRK1B,SMAD3,CAMK2D,AHNAK,BRCA2,TRRAP,SUFU,CHD3,HIPK2,HOXA3,RPS6KB1,RIOK1,RUNX1,MUTYH,SMG1,TNIK,BCKDK,BRAF,TAF1,CLK1,MAP3K13,ITPRIP,CAMK1,C10orf2,CMTM8,TRIO,PIK3R4,ZFP36L1,CCDC7,MLH1,CSNK1A1,TGFBR2,ABL1,PRKCH,PRKCE,SCN1B,CEP290,MYC,UNC13A,CTR9,MAP3K12,RPS6KB2,CLK2,TOP1,SIK3,CAMKK2,TEX14,OBSCN,ARID1A,MEN1,TMEM187,PIK3CB,RERE,OXSR1,EPRS,TRIB3,NSD1,INF2,LRP1B,PALB2,CUL2,STX18,RIOK3,ATM,NCOR1,WDR33,SORCS2,RPS6KC1,TBCK,ZAK,MAP2K4,NIT1,STK4 |
| 9.317e-03 | -4.68 | SNAPIN (SNAP-associated protein) | protein interactions | 23557 | 41 | 12 | 16036 | 2270 |
BCAS4,LAMC1,COPS4,SNAP23,DTNBP1,KIF5C,SNAP25,MET,IKBKAP,BLOC1S4,CEP170,BLOC1S2 |
| 9.317e-03 | -4.68 | TNIK (TRAF2 and NCK interacting kinase) | protein interactions | 23043 | 41 | 12 | 16036 | 2270 |
DST,DYNC1H1,TNIK,NCOR2,ACTG1,HARS,PAFAH1B1,ANK2,AGTPBP1,WWC1,CLU,NEDD4 |
| 9.332e-03 | -4.67 | HELLER_HDAC_TARGETS_DN | MSigDB lists | HELLER_HDAC_TARGETS_DN | 280 | 50 | 17758 | 2279 |
DNAJC2,CLK1,SEC24D,ST6GAL1,PBX1,VARS,CHAC1,ST3GAL6,HSPA1A,NOP56,IQGAP2,SLC7A11,PMAIP1,CNIH3,NOP16,FMNL1,ATIC,MYC,PPFIBP1,PAK1IP1,SHMT2,RAN,SERPINH1,CD44,AVEN,MYB,SLC3A2,ATF4,PSAT1,SLC38A1,ELOVL6,HSPA5,SUMO3,PHACTR2,IL6R,SERP1,UBE2E1,HERPUD1,HSPA1B,OSBPL1A,TIMM44,TRIB3,GADD45A,SET,MYOM2,PUS1,TNFRSF10D,ZNF532,DDIT3,LRRC41 |
| 9.335e-03 | -4.67 | V$PAX6_01 | MSigDB lists | V$PAX6_01 | 96 | 21 | 17758 | 2279 |
ARHGAP26,GPM6A,MAP2K5,TRERF1,TEAD1,WDPCP,JMJD1C,HSD17B10,SOX4,MBNL1,STOML2,BAZ1A,ZBED2,LUC7L3,RRAGA,PTPN4,FIP1L1,ETV1,YARS,MAML3,SRPK2 |
| 9.335e-03 | -4.67 | BROWNE_HCMV_INFECTION_12HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_12HR_DN | 96 | 21 | 17758 | 2279 |
PTP4A1,ZNF516,TUBA1A,APEX1,PRIM2,PAFAH1B1,EXOC6B,TRAK1,ID2,ATXN1,DENND3,UBR5,POP1,HNRNPH3,CBR4,RABGAP1L,RUNX1,TSPAN5,MID1,TBC1D8,VPS13B |
| 9.340e-03 | -4.67 | - | gene3d domains | 2.40.50.140 | 67 | 17 | 9988 | 1398 |
NARS2,MCM6,LIN28B,SUPT6H,NARS,LIG4,MCM2,MCM9,RPA1,BRCA2,SRBD1,MCM5,EIF2S1,SSBP1,YBX3,YARS,PDCD11 |
| 9.356e-03 | -4.67 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | 340 | 59 | 17758 | 2279 |
DMXL2,SERINC5,ATP6V1A,DYM,PSTPIP2,DCP1B,LETMD1,ANKRD18A,SPATS2,SSBP2,NBEAL1,CSTA,AHCYL2,FRRS1,GIPR,ABCA7,SLC25A20,C6orf48,AMPD3,SLC7A11,FGGY,ANXA5,ANO8,CHD2,TTC17,AGL,ATP6AP1L,SPTAN1,SLC38A6,GPHN,LIMA1,TEX19,TRA2A,ARRDC3,ATF7IP2,LIG4,ATXN1,EFHC1,PRDM1,R3HDM2,ANKRD20A4,ZNF91,NEU1,MGST1,ZNF251,RHOU,HLA-DMA,ZFAND3,SYCP2L,MTHFD2,RPL28,AGTPBP1,SDCCAG8,CCDC146,PSAP,TAF12,RNF130,CCNB1IP1,ZMAT3 |
| 9.364e-03 | -4.67 | MODULE_257 | MSigDB lists | MODULE_257 | 151 | 30 | 17758 | 2279 |
IFT43,TLE3,TRA2A,DLGAP4,ARFIP2,LRRC8A,WDR37,CCNL2,MEF2D,PPIP5K2,CHAF1A,EDC3,ABCA7,SKI,YIF1A,DCTPP1,CAD,RNF40,ELL,MCAM,SHC1,ATXN2,FAT1,PMPCA,ZNF3,TBCK,N4BP2,MUTYH,TNRC6A,MEF2C |
| 9.364e-03 | -4.67 | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | MSigDB lists | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | 151 | 30 | 17758 | 2279 |
ACSL5,ARHGAP17,EPM2AIP1,PSPC1,TRA2A,XPO5,PPHLN1,PNN,AKAP13,LENG8,NUP214,SNAPC4,SLC23A2,TJAP1,ATXN7,SRSF2,TRRAP,GPC2,DHX37,EHMT2,HNRNPH3,MCM5,HSPBAP1,ZNF142,RBM26,CHD2,FBXL19,ECHDC1,ZNF532,XPO6 |
| 9.377e-03 | -4.67 | GTCNYYATGR_UNKNOWN | MSigDB lists | GTCNYYATGR_UNKNOWN | 102 | 22 | 17758 | 2279 |
OXNAD1,ID1,TUBA1A,STX8,JMJD1C,MRPS10,ODC1,EHBP1,RING1,STOML2,DAGLA,SKIL,THADA,TP53BP1,TBPL1,CSMD3,GPN1,RAPGEFL1,FIS1,NLGN3,CCDC121,TSPAN5 |
| 9.393e-03 | -4.67 | oesophagus-middle_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-middle_third-carcinoma-squamous_cell_carcinoma | 3681 | 515 | 17775 | 2278 |
AARS2,TUBE1,SBF2,CSPP1,HLTF,ZNF44,LPAR3,AMBRA1,PDZD2,ZFHX3,AP1M1,MAD1L1,ZNF148,KLHL23,LIMA1,PTPRM,PACRGL,RFX2,WDHD1,AKAP12,SHISA5,ABCC2,STOML2,DDX3X,AHNAK,BRCA2,ZNF266,RBP1,MEF2C,HERC2,EP400,TMEM63C,CLDN15,TRIP6,PITPNM1,YARS2,ABCA7,SLC39A11,DHX37,KIAA1671,ZNF326,CCDC88C,FMNL2,SAMD3,GATAD2B,STAG1,MYO10,PRDM16,ARID5B,RYR2,ABCF1,DYNC1H1,LRP1B,CLASRP,KIAA0196,WDR33,SPRED2,RAB11FIP4,ABCA3,ZNF516,DDX18,VTI1A,DDR2,MYH9,UBL5,MCM9,RPGRIP1L,ZKSCAN1,WAC,C16orf58,INTS12,MSH4,ZC3H3,LYST,PMS1,GARS,KMT2D,FAM111B,SLCO6A1,PCNXL2,MEF2D,DSP,FKBP3,PDE8B,IQCH,CDC16,KDM4B,ASTN2,HIPK2,ARL13B,POLR3E,ANKS1A,LAMA5,YEATS2,LRCH1,MORC2,COMMD10,SHQ1,ATG2B,TGFB2,NOP16,ARHGAP1,HNRNPM,SPTAN1,DIS3L2,DDX24,ZC4H2,ARHGAP39,CCDC113,PPIP5K2,CCDC150,TRIB3,RARS,SRCAP,NSD1,PXDN,PLPPR2,HERC1,SLCO5A1,AEN,SORCS2,MTMR1,DOCK6,NUDT22,CORO2B,CUL7,TFIP11,FAM13A,TTI1,GIT2,SCAF8,BIRC2,MAP2K3,MARVELD2,NCKIPSD,ANKRD11,VPS13B,FAM184A,DSC3,FLNC,CHD9,SLC3A2,MIOS,HARS,KATNAL1,ANK2,MED27,NOL6,LAMA2,KCNH2,ZNF91,KIF16B,PEX1,TP53BP1,CHD3,TECPR2,TNFRSF1A,PRPF4,CHMP4C,ITFG1,NKD2,FAN1,MAPK8IP3,MEX3A,ARID1B,DNAH1,DOPEY1,KIAA1958,ABCA5,CEP290,VPS72,SAMD11,TIMELESS,SYNJ2,SNX29,TRAPPC9,CRADD,USP49,HOMER2,SETD2,UTP15,OBSCN,METTL22,SUPT5H,TRAPPC6B,GRIK4,ITPRIPL1,FAM135A,SPAG9,SYNCRIP,PALB2,TTC38,DNAH17,CASS4,DDX10,MPI,PAPD4,LPCAT2,LPCAT3,DENND3,TNKS1BP1,RADIL,URB1,KDM1A,CAD,JAG1,GRIN2C,UBR1,ARMC5,FSIP2,ANKRD24,CCDC40,ANO8,MYH15,KDM3B,KAT8,SOBP,WDR36,ARHGAP17,EVL,ANKRD33B,CPOX,AKAP13,NHSL1,ZNF251,BTBD11,EXO1,RANBP2,RBBP8,LMBR1L,ZNF333,CLEC16A,ITGA2,ZNF436,MED20,PARD3,FOXP1,RMI1,IQGAP2,PTPN2,SACS,ANXA7,CWC27,TRNP1,MON1A,FOXN3,ZMYM5,TEX14,DHX34,ARHGEF12,RHOT2,CHCHD6,ARMC3,SMPDL3B,POLR3A,ZRANB3,ZBTB8OS,TAF4,TBX3,FNTB,USP20,TMEM219,RBM26,ITGB4,NR2F2,LMBRD2,MYCBP2,POLB,TNFRSF21,NBEAL1,RAC3,GABPB2,UBR5,AARS,EXOC1,PAK1IP1,RNF111,TBC1D8,ENHO,DENND4A,SAP30BP,DOT1L,SH3GL1,TRRAP,CCNT1,NSMCE1,VPS13D,GREB1L,SEMA3C,FAM118A,SPOCK2,PTPN14,WDR75,CELSR1,ZHX3,ANKRD17,ANXA10,TECTA,NAV1,PI4KB,VWDE,SLC16A9,CNOT4,DDX28,RREB1,PRIM2,AOC2,KIAA0586,ARID1A,ZNF850,DAGLA,ASCC3,KIDINS220,HIF1A,UBAP1,ZZEF1,SPEN,VCAN,SQLE,DPEP1,NCOR1,MAP2K4,ZFHX2,CPT1C,PTCD2,TRPM2,AMOTL1,BIRC6,SPATA2L,ZBTB37,PABPC1L,FOSL2,SLC25A44,PDE3A,FLAD1,NUBPL,CHD7,ZNF827,SLX4,PPID,GLYR1,DTNBP1,NBEA,TTC3,KMT2A,CDK12,CASP8AP2,C18orf21,MPP6,C1orf228,LRRC8A,DLG4,MED16,POLG2,DHX57,CPED1,BAZ1A,DNTTIP1,ZNF236,SLC4A7,TRMT2A,IFT140,MDN1,KLHDC4,NOSTRIN,C10orf2,SLC25A12,FARS2,NFX1,RTN4,MON2,GIGYF2,ZNF239,ABL1,COMMD9,NEBL,NLGN3,DYNC2H1,NAV3,PSAT1,ZFYVE1,WDFY3,TMEM126B,BMS1,GUF1,RETSAT,INF2,KLHL22,ZNF155,ZDHHC11,COQ9,ORC5,SVIL,ATM,IMMP2L,PHF3,NF1,ATRX,SLC52A3,KIF5A,BCOR,SLC29A1,STK33,DST,RTN1,YLPM1,PCOLCE2,LONP1,TRIM14,CEP128,LAMA4,DEAF1,GPM6A,SESN2,ZNF195,SIRT6,VWCE,ARRDC3,MINA,MTHFD1L,ZSCAN2,KMT2C,PAF1,EIF4ENIF1,GATA6,RLTPR,CSMD3,ASB3,ABCC3,GALNT10,TNRC6A,SLC12A7,PIGN,FN1,TAF1,DPF2,SMG7,QSER1,XPO7,ELL,HVCN1,SIPA1L3,SEMA3D,PRF1,AKAP11,LRP3,RANBP6,JMJD1C,ELP3,WWC1,PRDM1,CORIN,AGAP1,EXOC6,POP1,SYCP2L,ATAD5,FSCN1,KIAA0754,FAT1,PFDN2,ZBTB24,DMXL2,PCNT,SLC5A5,CELSR3,PSTPIP2,MYO7A,COBLL1,ARSJ,RIOK2,CCDC50,SOCS1,LYPLAL1,PPFIBP1,ZNF142,MET,TMLHE,PARP2,ATXN1,ATP8B2,UBR4,WARS,TPK1,ARNTL,CEBPZ,FKBP5,SMG1,TMEM33,TNIK,DNAJC2,SH2D3A,CAMK1,CLSTN2,IGF2BP2,SEMA3E,PRKCH,IL17RE,DSG2,TMEM99,TTC17,PKNOX1,ARNTL2,KDM6B,DNMBP,KDM5A,PSMC3IP,METTL23,SCMH1,LENG8,TARS,RERE,AGTPBP1,MBD6,SLC16A10 |
| 9.402e-03 | -4.67 | IDENTICAL_PROTEIN_BINDING | MSigDB lists | IDENTICAL_PROTEIN_BINDING | 300 | 53 | 17758 | 2279 |
TTN,AOC3,MVK,AMOTL1,MCM6,CLDN15,TRIP6,ACTG1,MAP3K13,MRI1,TCF3,PLOD1,MYH9,SMARCA4,MED18,NOL3,TGFB2,EEA1,IGSF1,BLOC1S2,DCTPP1,PHC2,PVRL3,IKBKB,PDS5B,DTNBP1,SDCBP2,VAPB,UPF2,MAP3K12,CAV2,TRIP13,CASP10,NR6A1,PCMT1,ATXN1,RABAC1,POLG2,POP1,OXSR1,SMAD3,HPRT1,SUFU,MKL2,ORC5,IRAK2,ITGA2,RRAGA,MSH3,HSPB8,ACP1,ZAK,STK4 |
| 9.402e-03 | -4.67 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 300 | 53 | 17758 | 2279 |
HMGA2,PDE4B,GTF2IRD1,PBX1,PHGDH,LCLAT1,UBTD2,PPP1R9A,IGF2BP3,IQGAP2,FKBP1A,NUBPL,PRKD3,LYPLAL1,NISCH,GSTA4,ZNF518B,TRIM14,EIF4E3,GCNT2,SSFA2,SLC38A1,HOMER2,LGALS1,MARCKSL1,ATXN1,SCMH1,VIM,SOX4,ENC1,ARRDC4,PDE3B,RERE,TPK1,POLR3G,SKIL,HLA-DMA,KLHL22,IFT81,BRCA2,TMEM237,PDLIM1,L3MBTL3,HK2,SLC4A7,SVIL,TRAF3,FKBP5,SMYD3,PTPN14,FGFBP3,MEF2C,LRCH1 |
| 9.406e-03 | -4.67 | TRNASYNTHARG | prints domains | PR01038 | 2 | 2 | 4759 | 462 |
RARS,RARS2 |
| 9.406e-03 | -4.67 | TRNASYNTHTYR | prints domains | PR01040 | 2 | 2 | 4759 | 462 |
YARS,YARS2 |
| 9.406e-03 | -4.67 | CD97PROTEIN | prints domains | PR01278 | 2 | 2 | 4759 | 462 |
ADGRE5,ADGRE2 |
| 9.406e-03 | -4.67 | TRNASYNTHTRP | prints domains | PR01039 | 2 | 2 | 4759 | 462 |
WARS2,WARS |
| 9.406e-03 | -4.67 | TRNASYNTHALA | prints domains | PR00980 | 2 | 2 | 4759 | 462 |
AARS,AARS2 |
| 9.407e-03 | -4.67 | PROTEIN_RNA_COMPLEX_ASSEMBLY | MSigDB lists | PROTEIN_RNA_COMPLEX_ASSEMBLY | 67 | 16 | 17758 | 2279 |
SCAF11,EIF3C,PRPF31,SFSWAP,MTIF2,EIF3J,EIF4A2,SF3A3,EIF2A,EIF3H,PAIP2,ATXN2,CELF1,EIF2B3,SRPK2,SF3A1 |
| 9.416e-03 | -4.67 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 36 | 17758 | 2279 |
DCTN3,PTP4A1,LUZP1,PSTPIP2,CLINT1,GIT2,MAN1A1,CHD7,SH2B3,CTNNBL1,CEP63,VCL,CAV2,HTRA2,PERP,MYB,TIMM8B,SSFA2,RREB1,KDM5B,RB1CC1,PTPN12,TRIM37,ANXA1,ARPC3,SUPT4H1,BAZ2B,SERINC1,NSF,ACOX1,RIOK3,SVIL,RNF130,IFITM2,FNBP1L,BAG1 |
| 9.416e-03 | -4.67 | GSE27786_CD4_VS_CD8_TCELL_DN | MSigDB lists | GSE27786_CD4_VS_CD8_TCELL_DN | 189 | 36 | 17758 | 2279 |
GGT1,CHST11,WDR74,CCDC53,ALG8,FRRS1,NOP56,PUS3,RPS16,UCHL5,PRF1,KLRD1,USE1,HBG2,TRIM13,ZNF414,NARS,ZBED4,SLC35G1,MRRF,GSTCD,PDE2A,PDE3B,CLNS1A,TAMM41,KIAA0355,POLR3E,ORC5,SRFBP1,PPP3CC,CNDP2,ZC3H8,RABEP1,YEATS2,IPO4,TMEM141 |
| 9.416e-03 | -4.67 | GSE17721_LPS_VS_PAM3CSK4_4H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_4H_BMDM_DN | 189 | 36 | 17758 | 2279 |
TCF12,PTCD2,WDR75,SARS,ATP6V1A,RBFOX2,SLC2A1,XPO7,SLC6A8,SEC16A,KCNJ14,NUP160,REEP5,SLC39A1,SACS,SHC1,WIZ,LTN1,TTC3,POLE3,LYRM5,C12orf4,CLK2,ACSL5,IFNGR2,ELOVL6,RNH1,MEF2D,GALK2,ATP5D,HLCS,SMARCC1,CEBPZ,MBTD1,SENP3,TMEM101 |
| 9.416e-03 | -4.67 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | 189 | 36 | 17758 | 2279 |
ADAM19,ZNF516,EGR1,RBFOX2,MYH9,TUBB6,BHLHE40,SLC6A8,ANXA10,JAG1,PVRL3,ME1,PTGS1,BCAP29,PNMA1,CARM1,VOPP1,PEA15,SLC38A6,FGF2,UPP1,PTPN12,VIM,ARHGEF12,TBC1D16,FOXC1,DKK1,HIF1A,KLF4,LARGE,RPS6KC1,ZNF532,CEP170,TMEM158,CORO2B,HS2ST1 |
| 9.416e-03 | -4.67 | GSE11924_TH1_VS_TH17_CD4_TCELL_DN | MSigDB lists | GSE11924_TH1_VS_TH17_CD4_TCELL_DN | 189 | 36 | 17758 | 2279 |
CDCP1,SLK,PSTPIP2,SLC25A12,AKT1S1,GYG1,RPS6KA5,PITPNM1,MFSD10,RSPRY1,C6orf48,LTN1,RAPGEFL1,CHD2,ITGAX,DENND1A,RPS6KB2,SEC24A,AEBP2,TUBA1A,RNMT,UPP1,PCCA,PPP1R21,ARID5B,GPNMB,VDR,GPC2,MKL2,TMEM219,IFT140,DNAJC12,MED20,PSAP,SH3PXD2A,FAM118A |
| 9.416e-03 | -4.67 | GSE17721_POLYIC_VS_CPG_24H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDM_DN | 189 | 36 | 17758 | 2279 |
HERC2,BCCIP,SLC48A1,TNFRSF21,NUP160,MGA,FLNB,PRKCH,ATXN7L1,RRN3,HAS3,UBR1,KDELC1,CD44,CTC1,C12orf4,FAM98A,RNMT,C2orf76,NXN,RAP1GDS1,WWC1,CAV1,RBM28,TARS,OXSR1,SLC39A14,ARHGAP21,CDC16,ZBTB8OS,SLC4A7,ADAM9,GPN1,XRCC4,ZNF598,PTPN14 |
| 9.426e-03 | -4.66 | adenoma | COSMIC cancer mutations | adenoma | 2966 | 420 | 17775 | 2278 |
GGT1,MYCBP2,GNB3,PRKCSH,DCP1B,TNFRSF21,NAT10,MKS1,SBF2,CHAC1,CCNL2,PRKCA,SYNJ1,LPAR3,UBR5,LPIN1,MGA,AMBRA1,ZNF37A,PCDH7,PDZD2,ZFHX3,RNF111,VPS52,CHD2,KDM5C,HRG,AVEN,CNTNAP3B,SPAG6,ZNF646,TBC1D8,NRAS,KLHL23,PTPRM,RFX2,EFHC1,SEMA3F,ABCC2,SON,DDX60,SPOP,SKIL,AHNAK,BRCA2,TRRAP,ZNF266,CCNT1,VPS13D,DNAH2,GREB1L,SLC25A26,NMD3,ZMAT3,PTPN14,HERC2,CELSR1,FAM189B,PRPF31,TRIO,NHS,DLGAP4,TATDN3,RSF1,CDC73,CD226,PITPNM1,IGF2BP3,MTUS1,TECTA,DDX56,NAV1,TSPAN2,LDOC1L,COPS3,PIGG,MED24,GTF3C3,CCDC88C,CALN1,LPCAT1,ZNF518B,MAP3K12,PPA1,SERBP1,ANGPT2,LRRC20,SCAF11,USE1,SIK3,COL17A1,SYNGAP1,ALG6,WDR61,KCNQ3,PRDM16,RAPGEF4,TTYH2,SMARCD3,ARID1A,SRA1,ANGPTL4,ZNF783,IRS1,DYNC1H1,ZNF425,EPRS,LRP1B,UBAP1,HIF1A,VCAN,ZZEF1,ZCCHC6,IQSEC2,DHCR7,MAP2K4,COG5,SPRED2,PTCD2,RAB11FIP4,ABCA3,SYT17,TRPM2,BIRC6,ATP6V1A,NPAS2,HFM1,C1QTNF7,OLA1,MYH9,NECAP1,NUP43,ST3GAL6,SAFB2,HNRNPA3,FLNB,PDE3A,DECR1,ESAM,SHC1,ABCA12,VGF,WAC,MMP14,TTC3,SSBP1,KMT2A,ZC3H3,NAA35,LYST,C18orf21,ZCCHC14,KMT2D,BRD4,GON4L,NPM3,PCMT1,PREX1,ATP6V0A1,MEF2D,KCNH3,DSP,ERC1,HSD3B7,PDE8B,SLC39A14,CDC16,KDM4B,ASTN2,CAMKMT,POLR3E,WDR7,PAM,IFT140,TRAF3,MDN1,ZBTB11,LAMA5,MAPT,LRCH1,HMGA2,NCOR2,BRAF,SLC25A12,KIF5C,MON2,OPA1,IKBKAP,POLR3D,RGS17,NEBL,LRP2BP,PVRL3,UNC13A,UPF2,DYNC2H1,LARP4B,SAMD4A,HNRNPM,SPTAN1,NAV3,DDHD1,TMC7,FAM98A,APEX1,CLYBL,WDFY3,LSM12,FZD3,KCNMA1,TBRG4,RSBN1,FAM126B,SLC23A2,RPA1,YIF1A,SRCAP,IREB2,ORC5,ATM,MYOM2,APAF1,PSAP,GPAM,IGBP1,IMMP2L,PHF3,ATRX,NF1,KIF5A,TRPM6,RNF43,SIRT2,FAM13A,TMEM132A,DST,ANAPC1,JAZF1,ANKRD11,MYH3,TRIML2,GPATCH1,JOSD1,POLR3B,TRIM14,PTPRK,DSC3,FLNC,LAMA4,DEAF1,GPM6A,SESN2,ABCC4,ZNF680,SKIV2L2,KATNAL1,GPCPD1,LAMA2,BRCA1,CAV1,SGK2,KMT2C,KCNH2,KIF16B,PEX1,BSN,CHAF1A,RHOU,GEMIN5,PAF1,TCF7L1,GATA6,TP53BP1,DNAJC1,CHD3,TECPR2,CCDC146,RAD51B,SGSM2,CSMD3,ABCC3,GALNT10,COPS6,OXNAD1,CHST11,STX8,FN1,RHOBTB1,VTA1,ALG8,MAPK8IP3,PCSK7,PHGDH,ARID1B,DNAH1,ETFB,RNF40,SIPA1L3,ZNF354A,ABCA5,CTR9,ZCCHC7,NT5E,NAA38,RANBP6,LAMC1,TSTA3,IFT43,MEX3B,CORIN,ANKRD20A4,SYT1,AGAP1,NR2F1,TCF7L2,PGD,PWP1,NAP1L5,GRIK4,UBAP2,SPAG9,ATAD5,FSCN1,FAT1,DNAH17,CASS4,KIAA1328,DDX10,SH3PXD2A,TBCK,ZBTB24,TCF12,FEZ2,CYLD,ASH1L,PCNT,CELSR3,SLC5A5,TMEM183A,GPR143,PIGH,SSBP2,DENND3,TNKS1BP1,PPP1R9A,SLC39A1,PLXNB1,ZC3H13,NRF1,BRE,MPHOSPH10,FGGY,ZFP37,CORO1A,AKNAD1,MET,ITGAX,VCL,IPO11,MCEE,ARHGAP17,PHLDB2,KIRREL2,ANKRD33B,MANBAL,NLN,POU2F1,DKC1,UBR4,RAB10,USP36,SMAD3,SLC30A3,ALAD,KLF4,CEBPZ,ATG7,DISP1,NFASC,NFRKB,EIF2B3,USP11,TSPAN5,PARD3,DMGDH,SUPT6H,DYM,KLC4,CMTM8,CLSTN2,ARFIP2,BMP6,MAN1A1,IQGAP2,SACS,SEC24C,DDX31,TTC17,LDLRAD3,C12orf4,DNMBP,ADAMTSL3,ANKMY2,ZMYM5,TOP3A,SCMH1,PDE2A,MEN1,EIF5B,NAPEPLD,PIK3CB,MFN2,DAGLB,GPC2,TBX3,CSRNP1,RPS6KC1,KIF1B,MMP16,NIT1 |
| 9.443e-03 | -4.66 | POLR1A (polymerase (RNA) I polypeptide A) | protein interactions | 25885 | 56 | 15 | 16036 | 2270 |
UBTF,RRN3,MYBBP1A,SIRT7,SHMT2,RNF2,ANP32B,POLR1B,POLR3B,POLR1C,USP11,NFKBIB,NOLC1,POLR1E,POLR3A |
| 9.443e-03 | -4.66 | NR1H2 (nuclear receptor subfamily 1, group H, member 2) | protein interactions | 7376 | 56 | 15 | 16036 | 2270 |
VDR,USP7,NCOR2,CHD3,TMEM161A,PPARGC1B,SMARCA4,SENP3,VIM,NCOR1,PRKCA,NRIP1,FOXO3,RMI1,KDM1A |
| 9.443e-03 | -4.66 | POLR2H (polymerase (RNA) II (DNA directed) polypeptide H) | protein interactions | 5437 | 56 | 15 | 16036 | 2270 |
POLR3D,INTS5,POLR1A,TCEB3,CRCP,RNF2,BRCA1,POLR3B,POLR1B,POLR1C,NFKBIB,SUPT5H,ZNRD1,POLR2A,POLR3A |
| 9.444e-03 | -4.66 | BYSL (bystin-like) | protein interactions | 705 | 115 | 26 | 16036 | 2270 |
HMBOX1,TRIP6,UTP14A,DDX18,FAM207A,SIRT7,SMARCA4,RBM19,PARN,TRIM37,PHC2,DDX3X,TSR1,L3MBTL3,HERC1,COPS5,VPS37B,RNF2,SRFBP1,POLR1C,FBL,DDX10,MIPOL1,MID1,PNMA1,FTSJ3 |
| 9.478e-03 | -4.66 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | 170 | 33 | 17758 | 2279 |
NECAP1,RCAN1,SEMA3E,FOSL2,AARS,URB1,ABL2,PEX7,POLR3D,ANXA7,DHX37,WIZ,GEMIN4,FBXL19,PPA1,PRPF19,SESN2,TRIM13,CRIM1,TEAD1,TRA2A,USP42,C1QTNF1,NOL6,PTPN12,EIF2A,DCUN1D5,IMPDH2,BATF3,LSS,ZNF81,SEMA3C,IPO4 |
| 9.491e-03 | -4.66 | PCF11 (PCF11 cleavage and polyadenylation factor subunit) | protein interactions | 51585 | 27 | 9 | 16036 | 2270 |
BCAS2,EEFSEC,PLRG1,RANGAP1,FIP1L1,WDR33,PLCB1,PABPC4,RPA1 |
| 9.491e-03 | -4.66 | XPA (xeroderma pigmentosum, complementation group A) | protein interactions | 7507 | 27 | 9 | 16036 | 2270 |
HERC2,XPC,MSH3,ATM,GPN1,GTF2H1,NUP43,POLR2A,RPA1 |
| 9.491e-03 | -4.66 | RAD17 (RAD17 checkpoint clamp loader component) | protein interactions | 5884 | 27 | 9 | 16036 | 2270 |
RFC4,SNU13,RFC3,POLE2,H2AFX,ATM,USP20,POLE3,FOXO3 |
| 9.491e-03 | -4.66 | ATG12 (autophagy related 12) | protein interactions | 9140 | 27 | 9 | 16036 | 2270 |
WDFY3,ATG3,EXOC4,ATG7,MCL1,PTK2,CAV1,AUP1,SF3A1 |
| 9.509e-03 | -4.66 | Nhp2l1 (NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)) | protein interactions | 20826 | 46 | 13 | 16036 | 2270 |
SNU13,KPNA1,ZNHIT6,RSL1D1,FBL,DKC1,NOLC1,NOP58,PABPC1,URB1,PABPC4,GPATCH4,NOP56 |
| 9.509e-03 | -4.66 | SUPT6H (SPT6 homolog, histone chaperone) | protein interactions | 6830 | 46 | 13 | 16036 | 2270 |
RNF40,SUPT4H1,CUL7,S100A10,TBC1D22A,SIRT7,CSNK2A1,BRCA1,SUPT5H,BMI1,PDCD11,SLC39A1,POLR2A |
| 9.509e-03 | -4.66 | MAP3K14 (mitogen-activated protein kinase kinase kinase 14) | protein interactions | 9020 | 46 | 13 | 16036 | 2270 |
TANK,IKBKB,RIPK1,TRAF3,BRCA1,MAP3K14,FBL,IKBKAP,BIRC2,MAP2K4,CASP10,UBC,CDC37 |
| 9.519e-03 | -4.65 | PERK regulates gene expression | REACTOME pathways | R-HSA-381042 | 28 | 9 | 8202 | 1117 |
EXOSC2,ASNS,ATF4,HSPA5,EIF2S1,EXOSC4,PARN,HERPUD1,DDIT3 |
| 9.531e-03 | -4.65 | ubiquitin protein ligase binding | molecular function | GO:0031625 | 255 | 47 | 16491 | 2164 |
HERC2,USP7,CUL7,CUL4A,HM13,SCAMP3,PRDX6,FOXO1,ACTG1,STX8,UBXN1,NKD2,SMAD7,RIPK1,HSPA1A,AMBRA1,SKI,RNF40,CCDC50,TANK,FHIT,VCL,CASP10,PRKACB,ZNF675,KCNQ3,HSPA5,RANGAP1,BRCA1,KCNH2,UBE2K,TRIM37,POLR2A,HSPA1B,MFN2,SPOP,SMAD3,TRIB3,RAD18,HIF1A,PER1,CUL2,RRAGA,TRAF3,CLU,PRKAR2A,MID1 |
| 9.537e-03 | -4.65 | SEC13 (SEC13 homolog, nuclear pore and COPII coat complex component) | protein interactions | 6396 | 51 | 14 | 16036 | 2270 |
SEC31A,SARS,SESN2,MIOS,NUP133,SIRT7,RNF2,FUS,NUP43,CSNK1A1,NUP160,FLNB,SEH1L,PRPF19 |
| 9.539e-03 | -4.65 | MORF4L1 (mortality factor 4 like 1) | protein interactions | 10933 | 104 | 24 | 16036 | 2270 |
KAT8,EP400,HMBOX1,ASH1L,TUBA1A,ACTG1,TFCP2,KDM5A,ARRDC3,BRCA1,SRCAP,KPNA1,BRCA2,TRRAP,PALB2,SYNCRIP,EP400NL,L3MBTL3,HNRNPR,VPS72,MBTD1,VAPB,HNRNPM,EMSY |
| 9.540e-03 | -4.65 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Hodgkin_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Hodgkin_lymphoma | 20 | 7 | 17775 | 2278 |
ATM,SEC31A,SSBP2,BRAF,CYLD,NRAS,SOCS1 |
| 9.553e-03 | -4.65 | SANSOM_APC_MYC_TARGETS | MSigDB lists | SANSOM_APC_MYC_TARGETS | 202 | 38 | 17758 | 2279 |
VIPR1,MVK,TTC27,VARS,PHGDH,COX10,PABPC4,COMMD9,SRSF2,MYC,SHMT2,PRPF19,MTHFD1,METTL1,BDNF,PXN,DNMBP,SIGMAR1,TRA2A,ARHGEF12,IMPDH2,MEN1,SOX4,KLF6,UBE2K,DDX49,NSD1,DNAJC1,SRRD,HSPBAP1,BIVM,BCAS3,USP20,MDN1,TATDN1,WDR33,TXN2,DCAF5 |
| 9.577e-03 | -4.65 | V$PAX5_01 | MSigDB lists | V$PAX5_01 | 145 | 29 | 17758 | 2279 |
FLNC,PRPF38B,IL11RA,WDPCP,ARFIP2,MEX3B,JMJD6,NECAP1,ARHGEF12,BCOR,ARID1A,DNAJC22,GSTCD,SYNJ1,POLR2A,NR2F1,TCF7L2,PAIP2,UBTF,PRKCE,SH2B3,NRF1,ATP5G2,CDK9,HIC2,INTS12,RAPGEFL1,ZNF710,MAML3 |
| 9.583e-03 | -4.65 | RNA localization | biological process | GO:0006403 | 168 | 33 | 16441 | 2138 |
THOC5,PRPF31,SUPT6H,DDX19A,KIF5C,SMG7,IGF2BP2,NUP43,XPO7,NUP160,HNRNPA3,POM121,IGF2BP3,SRSF2,NUP133,ZNHIT6,ATXN2,UPF2,RAN,IGF2BP1,FBL,CPSF3,ZC3H3,SEH1L,EXOSC2,XPO5,NOL6,NUP214,NOP58,RANBP2,BICD1,NCBP2,SMG1 |
| 9.612e-03 | -4.64 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | MSigDB lists | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | 20 | 7 | 17758 | 2279 |
UBTF,GTF2H1,GTF2H3,POLR1B,PTRF,POLR1C,POLR1A |
| 9.612e-03 | -4.64 | WENG_POR_DOSAGE | MSigDB lists | WENG_POR_DOSAGE | 20 | 7 | 17758 | 2279 |
ANXA5,RETSAT,ANTXR2,ASNS,ENTPD5,ACTG1,LGALS1 |
| 9.612e-03 | -4.64 | RNA_EXPORT_FROM_NUCLEUS | MSigDB lists | RNA_EXPORT_FROM_NUCLEUS | 20 | 7 | 17758 | 2279 |
SMG7,NCBP2,UPF2,NUP160,NUP133,KHDRBS1,SMG1 |
| 9.620e-03 | -4.64 | V$STAT_01 | MSigDB lists | V$STAT_01 | 241 | 44 | 17758 | 2279 |
FN1,SCAMP3,PPARGC1B,STXBP6,C1QTNF7,SBF2,TRIM15,ZFP36L1,NEDD4,MAP2K3,SLC38A5,NEK6,UBR1,ATP5G2,SEC24C,VGF,MED24,ADCK4,CNOT4,PNMA1,IPO11,PPP1R9B,BDNF,MPP6,ADAMTSL3,IFT43,POLK,RDH10,HOMER2,COL4A3BP,PRDM1,SYMPK,RAB10,HSD3B7,PDLIM1,NME7,EHMT2,HNRNPR,ARL6IP5,SET,MBD6,CLU,NRP1,ATXN7L2 |
| 9.629e-03 | -4.64 | exonuclease activity | molecular function | GO:0004527 | 77 | 18 | 16491 | 2164 |
EXOSC2,APEX1,POLA1,FAN1,ISG20L2,APTX,PARN,EXO1,TOE1,APLF,ERI1,AEN,CNOT6,EXOSC4,CPSF3,ERI3,NOCT,DIS3L2 |
| 9.666e-03 | -4.64 | Mitotic Spindle Checkpoint | REACTOME pathways | R-HSA-69618 | 19 | 7 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10,MAD1L1 |
| 9.672e-03 | -4.64 | lipid oxidation | biological process | GO:0034440 | 72 | 17 | 16441 | 2138 |
MCEE,ACADS,SESN2,PPARG,PCCA,CPT1A,ACOXL,MMAA,ECH1,ETFB,PEX7,ETFDH,DECR1,ACOX1,BDH2,PEX13,CPT1C |
| 9.674e-03 | -4.64 | NCBP1 (nuclear cap binding protein subunit 1) | protein interactions | 4686 | 77 | 19 | 16036 | 2270 |
THOC5,GARS,FN1,LIN28B,SIRT7,IMPDH2,ZNF346,ERC1,PGD,TTC1,RNF40,DYNC1H1,COPS5,RNF2,NCBP2,RPS6KB1,PUS1,PRMT5,BMI1 |
| 9.702e-03 | -4.64 | GGTGAAG,MIR-412 | MSigDB lists | GGTGAAG,MIR-412 | 56 | 14 | 17758 | 2279 |
FKBP1A,WARS2,TRMT5,HIF1A,ANK2,ABHD3,ARRDC3,BRCA1,IQSEC2,FOXO3,FMNL2,SOX6,BSN,CLK2 |
| 9.702e-03 | -4.64 | GCM_PTPRD | MSigDB lists | GCM_PTPRD | 56 | 14 | 17758 | 2279 |
FADS1,HERC2,SIK3,ANKRD17,RASSF3,ZFP14,TTYH2,PTK2,PREPL,ABHD6,RABEP1,KIF1B,SPIRE1,GZF1 |
| 9.702e-03 | -4.64 | ZWANG_EGF_PERSISTENTLY_DN | MSigDB lists | ZWANG_EGF_PERSISTENTLY_DN | 56 | 14 | 17758 | 2279 |
ESAM,ERVMER34-1,TMEM126A,HECTD3,ARHGEF10,ACOT11,FARS2,ABCC3,RWDD2B,CCNDBP1,PCK2,MACROD1,FOXP1,CTC1 |
| 9.716e-03 | -4.63 | cytoplasmic ribonucleoprotein granule | cellular component | GO:0036464 | 134 | 27 | 17570 | 2233 |
TUBA1A,BTBD2,DCP1B,AGO2,MEX3A,MEX3B,MBNL1,PABPC4,EDC3,YTHDF2,DDX3X,EIF4ENIF1,RPL28,LSM14A,ATXN2,ARNTL,PQBP1,EIF2S1,IGF2BP1,LARP4B,NOCT,PABPC1,AGO3,MAPT,DIS3L2,TNRC6A,TOP1 |
| 9.721e-03 | -4.63 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 183 | 35 | 17758 | 2279 |
ADAM19,ST6GAL1,HECTD3,NHS,MED13L,ATG2B,HMOX2,TGFBR2,LCLAT1,RMI1,FAM8A1,IQGAP2,HVCN1,RABGAP1L,UPF2,ARHGAP1,MAP3K14,VCL,CDK6,HSD17B12,SLC40A1,DDX28,PXN,ANAPC13,TUBA1A,PDE3B,G6PD,HERC1,MBTD1,GALNT10,TBL1X,ZMAT3,STK4,TMCC1,RNF114 |
| 9.721e-03 | -4.63 | PENG_LEUCINE_DEPRIVATION_DN | MSigDB lists | PENG_LEUCINE_DEPRIVATION_DN | 183 | 35 | 17758 | 2279 |
SRM,ALG8,TMEM109,SLC29A1,PSMF1,KDM1A,MAP2K3,NOP56,CAD,FARSA,GART,IDI1,NOP16,DNAJB6,UBAP2L,ETF1,LPCAT1,ZC3H3,TRIP13,SF3A1,MTHFD1,FAM98A,PSMC3IP,HSPA5,LDHA,UBC,HPRT1,TIMM17A,CEBPZ,FDPS,TNFRSF1A,SQLE,EIF2S1,UMPS,XPO6 |
| 9.721e-03 | -4.63 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN | 183 | 35 | 17758 | 2279 |
CARS,CHMP2A,PIGM,EGR1,MED18,PPIL1,BCOR,ZNF709,NLE1,AARS,RING1,POLR3D,SHMT2,GNG5,NT5E,TOP1,FAM98A,SEC24A,ZNF234,EIF3J,CDK4,RBM28,SLC7A1,MTHFD2,RBBP8,TP53BP1,COPS5,ZNF557,DNAJA3,RRAGA,ZCCHC6,TRAF3,CENPBD1,MED20,GPATCH4 |
| 9.721e-03 | -4.63 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN | 183 | 35 | 17758 | 2279 |
CHST11,ZNF516,APRT,C11orf54,TGFB2,RBM19,ABHD6,IGF2BP3,ZNF239,SNW1,KCTD11,PSMG4,NEK6,ABCA5,DSG2,TMEM14C,SAMD4A,FMNL2,PERP,LAMA4,SKAP2,KATNAL1,WDR18,RFX2,PLEKHM3,TOR1AIP2,DSP,PLIN2,EIF4ENIF1,HSDL2,METTL6,SET,CCNB1IP1,COPS6,SLC16A10 |
| 9.721e-03 | -4.63 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN | 183 | 35 | 17758 | 2279 |
SRM,CHMP2A,PIGM,AK2,MED18,PPIL1,AARS,ZNF239,DCTPP1,POLR3D,EIF2S2,ASNS,DNAJB6,WIZ,FTSJ3,PKNOX1,LYST,NT5E,USE1,ZNF234,MPP6,CDK4,PSMG1,MRRF,PEAK1,RBM28,TMEM206,TIMM44,POP1,SLC39A14,TP53BP1,ARL13B,UMPS,DDX10,IPO4 |
| 9.721e-03 | -4.63 | GSE3982_BASOPHIL_VS_TH1_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_UP | 183 | 35 | 17758 | 2279 |
KLHL24,CLK1,KIF5A,POGZ,LPIN1,IQGAP2,SH2B3,EXOC1,YLPM1,PTGS1,VCL,PRKACB,FAM172A,KDM5A,EIF4A2,R3HDM2,HIST1H4J,POLR2A,RERE,FBXL5,ZNF266,IQCH,BAZ2B,SERINC1,LSM14A,SPEN,AGTPBP1,RRAGA,ATM,SVIL,ZNF32,IFITM2,MAP2K4,N4BP2L2,USP15 |
| 9.724e-03 | -4.63 | regulatory region nucleic acid binding | molecular function | GO:0001067 | 795 | 127 | 16491 | 2164 |
TCF12,ZNF516,NPAS2,SMARCA4,PBX1,BCOR,HLTF,FOSL2,GABPB2,KDM1A,SMARCB1,CHD7,RRN3,NRF1,SREBF2,ZFHX3,IKZF5,RELB,ZEB1,ZNF148,CHD2,ZNF85,ZNF460,ETV1,KMT2A,LONP1,CARM1,DDN,AEBP2,KMT2D,ATF4,ZNF195,PPARG,ZNF680,BAZ2A,NR6A1,ZNF480,NFIA,CUX1,RFX2,POU2F1,MEF2D,BRCA1,ZSCAN2,SOX4,SNCA,GZF1,BATF3,VDR,TAF2,SMAD3,UBTF,SKIL,MSX2,TCF7L1,SMARCC1,GATA6,IKZF4,CCNT1,SIX5,CC2D1B,PER1,KLF4,E2F4,ARNTL,CEBPZ,RUNX1,DLX2,ZC3H8,ZBTB11,MEF2C,HMGA2,EGR1,TAF1,RFX1,PAX2,TCF3,DPF2,AGO2,SMAD7,NFX1,HES6,BARX2,BHLHE40,ZNF691,FOXO3,MLX,ZNF586,ZNF561,SUV39H2,MBD2,MYC,YBX3,PRMT5,NRIP1,DMRT1,SOX6,MYB,TOP1,ARNTL2,ZNF675,GATAD2B,MSX1,RREB1,PAXBP1,ZNF821,PSPC1,ARID5B,PRDM1,MEN1,ONECUT2,FOXC1,TCF7L2,ZNF708,NSD1,MYBBP1A,GADD45A,ARID3B,CDK9,TBX3,PURB,ZNF430,RBPJ,NCOR1,TBL1X,SMYD3,DDIT3 |
| 9.724e-03 | -4.63 | regulatory region DNA binding | molecular function | GO:0000975 | 795 | 127 | 16491 | 2164 |
TCF12,ZNF516,NPAS2,SMARCA4,PBX1,BCOR,HLTF,FOSL2,GABPB2,KDM1A,SMARCB1,CHD7,RRN3,NRF1,SREBF2,ZFHX3,IKZF5,RELB,ZEB1,ZNF148,CHD2,ZNF85,ZNF460,ETV1,KMT2A,LONP1,CARM1,DDN,AEBP2,KMT2D,ATF4,ZNF195,PPARG,ZNF680,BAZ2A,NR6A1,ZNF480,NFIA,CUX1,RFX2,POU2F1,MEF2D,BRCA1,ZSCAN2,SOX4,SNCA,GZF1,BATF3,VDR,TAF2,SMAD3,UBTF,SKIL,MSX2,TCF7L1,SMARCC1,GATA6,IKZF4,CCNT1,SIX5,CC2D1B,PER1,KLF4,E2F4,ARNTL,CEBPZ,RUNX1,DLX2,ZC3H8,ZBTB11,MEF2C,HMGA2,EGR1,TAF1,RFX1,PAX2,TCF3,DPF2,AGO2,SMAD7,NFX1,HES6,BARX2,BHLHE40,ZNF691,FOXO3,MLX,ZNF586,ZNF561,SUV39H2,MBD2,MYC,YBX3,PRMT5,NRIP1,DMRT1,SOX6,MYB,TOP1,ARNTL2,GATAD2B,ZNF675,MSX1,RREB1,PAXBP1,ZNF821,PSPC1,ARID5B,PRDM1,MEN1,ONECUT2,FOXC1,TCF7L2,ZNF708,NSD1,MYBBP1A,GADD45A,ARID3B,CDK9,TBX3,PURB,ZNF430,RBPJ,NCOR1,TBL1X,SMYD3,DDIT3 |
| 9.732e-03 | -4.63 | human chr10pter-q25.3 | chromosome location | human chr10pter-q25.3 | 2 | 2 | 26250 | 2590 |
ASCC1,SPOCK2 |
| 9.732e-03 | -4.63 | human chr10p14-p13 | chromosome location | human chr10p14-p13 | 2 | 2 | 26250 | 2590 |
UPF2,STAM |
| 9.749e-03 | -4.63 | regulation of sequence-specific DNA binding transcription factor activity | biological process | GO:0051090 | 363 | 63 | 16441 | 2138 |
USP7,ID1,MAP2K5,CYLD,JUP,MAP3K13,PPARGC1B,TCF3,DDR2,SMAD7,SMARCA4,PBX1,RIPK1,ID2,ZIC2,TRIM15,GAS6,TRIM22,BHLHE40,RPS6KA5,HSPA1A,MAD2L2,KDM1A,SMARCB1,TERF2IP,PRKCH,HR,TAF3,IKBKB,BUD31,RNF2,TRIM14,MBTPS2,ZNF675,BDNF,TRIM13,RBCK1,PPARG,ARID5B,IL6R,MEN1,TRIM37,ERC1,UBC,TCF7L2,SPOP,HSPA1B,CAT,ZC3H12A,MSX2,SUFU,TP53BP1,HIPK2,DNAJA3,KLF4,IRAK2,TRAF3,CLU,TAF12,NFKBIB,SETD6,DDIT3,KAT6A |
| 9.762e-03 | -4.63 | middle_third | COSMIC cancer mutations | middle_third | 3683 | 515 | 17775 | 2278 |
AARS2,TUBE1,SBF2,CSPP1,HLTF,ZNF44,LPAR3,AMBRA1,PDZD2,ZFHX3,AP1M1,MAD1L1,ZNF148,KLHL23,LIMA1,PTPRM,PACRGL,RFX2,WDHD1,AKAP12,SHISA5,ABCC2,STOML2,DDX3X,AHNAK,BRCA2,ZNF266,RBP1,MEF2C,HERC2,EP400,TMEM63C,CLDN15,TRIP6,PITPNM1,YARS2,ABCA7,SLC39A11,DHX37,KIAA1671,ZNF326,CCDC88C,FMNL2,SAMD3,GATAD2B,STAG1,MYO10,PRDM16,ARID5B,RYR2,ABCF1,DYNC1H1,LRP1B,CLASRP,KIAA0196,WDR33,SPRED2,RAB11FIP4,ABCA3,ZNF516,DDX18,VTI1A,DDR2,MYH9,UBL5,MCM9,RPGRIP1L,ZKSCAN1,WAC,C16orf58,INTS12,MSH4,ZC3H3,LYST,PMS1,GARS,KMT2D,FAM111B,SLCO6A1,PCNXL2,MEF2D,DSP,FKBP3,PDE8B,IQCH,CDC16,KDM4B,ASTN2,HIPK2,ARL13B,POLR3E,ANKS1A,LAMA5,YEATS2,LRCH1,MORC2,COMMD10,SHQ1,ATG2B,TGFB2,NOP16,ARHGAP1,HNRNPM,SPTAN1,DIS3L2,DDX24,ZC4H2,ARHGAP39,CCDC113,PPIP5K2,CCDC150,TRIB3,RARS,SRCAP,NSD1,PXDN,PLPPR2,HERC1,SLCO5A1,AEN,SORCS2,MTMR1,DOCK6,NUDT22,CORO2B,CUL7,TFIP11,FAM13A,TTI1,GIT2,SCAF8,BIRC2,MAP2K3,MARVELD2,NCKIPSD,ANKRD11,VPS13B,FAM184A,DSC3,FLNC,CHD9,SLC3A2,MIOS,HARS,KATNAL1,ANK2,MED27,NOL6,LAMA2,KCNH2,ZNF91,KIF16B,PEX1,TP53BP1,CHD3,TECPR2,TNFRSF1A,PRPF4,CHMP4C,ITFG1,NKD2,FAN1,MAPK8IP3,MEX3A,ARID1B,DNAH1,DOPEY1,KIAA1958,ABCA5,CEP290,VPS72,SAMD11,TIMELESS,SYNJ2,SNX29,TRAPPC9,CRADD,USP49,HOMER2,SETD2,UTP15,OBSCN,METTL22,SUPT5H,TRAPPC6B,GRIK4,ITPRIPL1,FAM135A,SPAG9,SYNCRIP,PALB2,TTC38,DNAH17,CASS4,DDX10,MPI,PAPD4,LPCAT2,LPCAT3,DENND3,TNKS1BP1,RADIL,URB1,KDM1A,CAD,JAG1,GRIN2C,UBR1,ARMC5,FSIP2,ANKRD24,CCDC40,ANO8,MYH15,KDM3B,KAT8,SOBP,WDR36,ARHGAP17,EVL,ANKRD33B,CPOX,AKAP13,NHSL1,ZNF251,BTBD11,EXO1,RANBP2,RBBP8,LMBR1L,ZNF333,CLEC16A,ITGA2,ZNF436,MED20,PARD3,FOXP1,RMI1,IQGAP2,PTPN2,SACS,ANXA7,CWC27,TRNP1,MON1A,FOXN3,ZMYM5,TEX14,DHX34,ARHGEF12,RHOT2,CHCHD6,ARMC3,SMPDL3B,POLR3A,ZRANB3,ZBTB8OS,TAF4,TBX3,FNTB,USP20,TMEM219,RBM26,ITGB4,NR2F2,LMBRD2,MYCBP2,POLB,TNFRSF21,NBEAL1,RAC3,GABPB2,UBR5,AARS,EXOC1,PAK1IP1,RNF111,TBC1D8,ENHO,DENND4A,SAP30BP,DOT1L,SH3GL1,TRRAP,CCNT1,NSMCE1,VPS13D,GREB1L,SEMA3C,FAM118A,SPOCK2,PTPN14,WDR75,CELSR1,ZHX3,ANKRD17,ANXA10,TECTA,NAV1,PI4KB,VWDE,SLC16A9,CNOT4,DDX28,RREB1,PRIM2,AOC2,KIAA0586,ARID1A,ZNF850,DAGLA,ASCC3,KIDINS220,HIF1A,UBAP1,ZZEF1,SPEN,VCAN,SQLE,DPEP1,NCOR1,MAP2K4,ZFHX2,CPT1C,PTCD2,TRPM2,AMOTL1,BIRC6,SPATA2L,ZBTB37,PABPC1L,FOSL2,SLC25A44,PDE3A,FLAD1,NUBPL,CHD7,ZNF827,SLX4,PPID,GLYR1,DTNBP1,NBEA,TTC3,KMT2A,CDK12,CASP8AP2,C18orf21,MPP6,C1orf228,LRRC8A,DLG4,MED16,POLG2,DHX57,CPED1,BAZ1A,DNTTIP1,ZNF236,SLC4A7,TRMT2A,IFT140,MDN1,KLHDC4,NOSTRIN,C10orf2,SLC25A12,FARS2,NFX1,RTN4,MON2,GIGYF2,ZNF239,ABL1,COMMD9,NEBL,NLGN3,DYNC2H1,NAV3,PSAT1,ZFYVE1,WDFY3,TMEM126B,BMS1,GUF1,RETSAT,INF2,KLHL22,ZNF155,ZDHHC11,COQ9,ORC5,SVIL,ATM,IMMP2L,PHF3,NF1,ATRX,SLC52A3,KIF5A,BCOR,SLC29A1,STK33,DST,RTN1,YLPM1,PCOLCE2,LONP1,TRIM14,CEP128,LAMA4,DEAF1,GPM6A,SESN2,ZNF195,SIRT6,VWCE,ARRDC3,MINA,MTHFD1L,ZSCAN2,KMT2C,PAF1,EIF4ENIF1,GATA6,RLTPR,CSMD3,ASB3,ABCC3,GALNT10,TNRC6A,SLC12A7,PIGN,FN1,TAF1,DPF2,SMG7,QSER1,XPO7,ELL,HVCN1,SIPA1L3,SEMA3D,PRF1,AKAP11,LRP3,RANBP6,JMJD1C,ELP3,WWC1,PRDM1,CORIN,AGAP1,EXOC6,POP1,SYCP2L,ATAD5,FSCN1,KIAA0754,FAT1,PFDN2,ZBTB24,DMXL2,PCNT,SLC5A5,CELSR3,PSTPIP2,MYO7A,COBLL1,ARSJ,RIOK2,CCDC50,SOCS1,LYPLAL1,PPFIBP1,ZNF142,MET,TMLHE,PARP2,ATXN1,ATP8B2,UBR4,WARS,TPK1,ARNTL,CEBPZ,FKBP5,SMG1,TMEM33,TNIK,DNAJC2,SH2D3A,CAMK1,CLSTN2,IGF2BP2,SEMA3E,PRKCH,IL17RE,DSG2,TMEM99,TTC17,PKNOX1,ARNTL2,KDM6B,DNMBP,KDM5A,PSMC3IP,METTL23,SCMH1,LENG8,TARS,RERE,AGTPBP1,MBD6,SLC16A10 |
| 9.779e-03 | -4.63 | V$STAT3_02 | MSigDB lists | V$STAT3_02 | 139 | 28 | 17758 | 2279 |
ZBTB17,EGR1,GPHN,ZC3H18,VSNL1,COL4A3BP,SMG7,ST7L,KCNH3,UBR5,TCF7L2,ZBTB25,TJAP1,UBTF,SOCS1,ATG3,SET,SLCO5A1,SENP3,S100A14,BMP4,MBD6,RBPJ,VCL,BMI1,ZBTB11,DDIT3,TNRC6A |
| 9.801e-03 | -4.63 | - | gene3d domains | 1.10.12.10 | 4 | 3 | 9988 | 1398 |
HIBCH,AUH,ECH1 |
| 9.803e-03 | -4.63 | TRIM72 (tripartite motif containing 72, E3 ubiquitin protein ligase) | protein interactions | 493829 | 7 | 4 | 16036 | 2270 |
MYH9,TCF12,PTK2,PTRF |
| 9.803e-03 | -4.63 | GALT (galactose-1-phosphate uridylyltransferase) | protein interactions | 2592 | 7 | 4 | 16036 | 2270 |
TNK2,UBTD2,TRIP13,ARPC3 |
| 9.803e-03 | -4.63 | ACOT8 (acyl-CoA thioesterase 8) | protein interactions | 10005 | 7 | 4 | 16036 | 2270 |
RNF2,KLHL23,MYC,ISG15 |
| 9.803e-03 | -4.63 | XIRP1 (xin actin binding repeat containing 1) | protein interactions | 165904 | 7 | 4 | 16036 | 2270 |
FLNC,ENAH,EVL,NEBL |
| 9.803e-03 | -4.63 | GPR25 (G protein-coupled receptor 25) | protein interactions | 2848 | 7 | 4 | 16036 | 2270 |
VAPB,GGT7,NAALADL2,PNMA1 |
| 9.803e-03 | -4.63 | Ep300 (E1A binding protein p300) | protein interactions | 328572 | 7 | 4 | 16036 | 2270 |
CCNT1,FOXO3,CDK9,POLR2A |
| 9.803e-03 | -4.63 | IL36RN (interleukin 36 receptor antagonist) | protein interactions | 26525 | 7 | 4 | 16036 | 2270 |
SKIL,MCM6,SSBP2,ZNF512B |
| 9.803e-03 | -4.63 | RNF169 (ring finger protein 169) | protein interactions | 254225 | 7 | 4 | 16036 | 2270 |
DYRK1B,BRCA1,UBC,UBE2E1 |
| 9.803e-03 | -4.63 | GGT1 (gamma-glutamyltransferase 1) | protein interactions | 2678 | 7 | 4 | 16036 | 2270 |
GGT1,GYG1,KCNMA1,NAMPT |
| 9.803e-03 | -4.63 | RIBIN (rRNA promoter binding protein) | protein interactions | 125168 | 7 | 4 | 16036 | 2270 |
UBTF,RRN3,POLR1B,MYC |
| 9.803e-03 | -4.63 | NAIF1 (nuclear apoptosis inducing factor 1) | protein interactions | 203245 | 7 | 4 | 16036 | 2270 |
TERF2IP,CCNDBP1,INTS5,TERF2 |
| 9.803e-03 | -4.63 | HMGN3 (high mobility group nucleosomal binding domain 3) | protein interactions | 9324 | 7 | 4 | 16036 | 2270 |
TERF2IP,VDR,TERF2,SRPK2 |
| 9.803e-03 | -4.63 | HTB1 (histone H2B) | protein interactions | 851810 | 7 | 4 | 16036 | 2270 |
ATXN7,EP400,SRCAP,MCM2 |
| 9.875e-03 | -4.62 | regulation of mitotic sister chromatid segregation | biological process | GO:0033047 | 50 | 13 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,NSMCE2,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,MAD2L2,ANAPC4,UBE2E1 |
| 9.884e-03 | -4.62 | MODULE_105 | MSigDB lists | MODULE_105 | 196 | 37 | 17758 | 2279 |
CARS,TCF12,UBXN1,HSD17B10,BIRC2,IGF2BP3,GART,IDI1,ASNS,SREBF2,PMAIP1,LPIN2,MAD1L1,GTF2H1,KDM5C,NRIP1,ADARB1,PFKFB4,MALL,COL5A2,LGALS1,SUPT5H,SOX4,FGFR1,ANXA1,RPA1,CHAF1A,PLIN2,HELZ,VCAN,ADAM9,NCBP2,UMPS,NOLC1,TROVE2,RBP1,GCSH |
| 9.939e-03 | -4.61 | V$CETS1P54_01 | MSigDB lists | V$CETS1P54_01 | 248 | 45 | 17758 | 2279 |
INSIG2,HM13,WDR74,NF1,PIK3R4,PPHLN1,PPIL1,AKT1S1,AP1B1,SLC30A7,CEP164,SHC1,SEC24C,AP1M1,VPS52,CTR9,CHD2,ARHGAP1,CELF1,OGG1,PNMA1,PRKACB,CSGALNACT2,LYPLA2,PRPF19,NRAS,CRADD,IL11RA,BAZ2A,TFCP2,MTIF2,FOXN3,KRTCAP2,DLST,ARL5B,STK10,STOML2,PALB2,DNAJC1,PTRH2,ZBTB11,DMTF1,LRRC41,STK4,MEF2C |
| 9.973e-03 | -4.61 | HDMs demethylate histones | REACTOME pathways | R-HSA-3214842 | 48 | 13 | 8202 | 1117 |
KDM6B,KDM3B,KDM4B,KDM2A,KDM5B,KDM5A,ARID5B,HIST2H3D,JMJD6,HIST1H4J,KDM5C,KDM1A,KDM4C |
| 9.973e-03 | -4.61 | RNA Polymerase I Transcription Initiation | REACTOME pathways | R-HSA-73762 | 48 | 13 | 8202 | 1117 |
UBTF,GATAD2B,GTF2H3,RRN3,EHMT2,CHD3,GTF2H2C,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 1.001e-02 | -4.60 | chr17q25 | MSigDB lists | chr17q25 | 158 | 31 | 17758 | 2279 |
UNC13D,CCDC57,MIF4GD,ACTG1,C17orf80,TEX19,SIRT7,C1QTNF1,METTL23,TTYH2,JMJD6,TMEM104,EVPL,TBC1D16,SAP30BP,RAC3,SLC26A11,USP36,PYCR1,SRSF2,DCXR,SRP68,SYNGR2,ANAPC11,DNAH17,CCDC40,SLC25A19,NT5C,B3GNTL1,ITGB4,HN1 |
| 1.003e-02 | -4.60 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | 177 | 34 | 17758 | 2279 |
PPDPF,SART1,WDR74,UBXN1,SSBP2,AP1B1,BHLHE40,DENND3,GIT2,MGA,SH2B3,FAM192A,RNF141,PEX7,SOCS1,ZFP37,CORO1A,CLK2,PTPRK,NT5E,FGF9,GPM6A,EVL,RBCK1,TRIM13,PTBP2,GON4L,IL11RA,KIF16B,CHD3,KLF4,RIOK3,GALNT10,ZMAT3 |
| 1.003e-02 | -4.60 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | 177 | 34 | 17758 | 2279 |
ZNF706,MCM6,ACTG1,ALG8,SPATS2,GYG1,SSR4,PABPC4,MAN1A1,DECR1,S100A10,INTS7,ANXA5,HIBCH,MGLL,PPA1,HN1,CDK4,HSPA5,GNG7,LGALS1,PSMG1,CAV1,MGAT2,DDAH2,RETSAT,RBBP8,MTHFD2,TTC38,SIL1,ANXA2,BRCC3,BLMH,AP2S1 |
| 1.004e-02 | -4.60 | Height(PMID:19343178) | GWAS genes | Height(PMID:19343178) | 12 | 6 | 2389 | 419 |
HMGA2,ADAMTSL3,UQCC1,CDK6,JAZF1,ADGRG6 |
| 1.004e-02 | -4.60 | GNF2_NS | MSigDB lists | GNF2_NS | 40 | 11 | 17758 | 2279 |
EPRS,MTHFD2,SKIV2L2,ATIC,GNL3,OLA1,MRPS27,ADSL,SSBP1,IMPDH2,RAN |
| 1.005e-02 | -4.60 | DNA strand elongation | REACTOME pathways | R-HSA-69190 | 33 | 10 | 8202 | 1117 |
RFC4,MCM6,RFC3,APEX1,GINS3,PRIM2,POLA1,MCM5,MCM2,RPA1 |
| 1.008e-02 | -4.60 | regulation of viral transcription | biological process | GO:0046782 | 78 | 18 | 16441 | 2138 |
HMGA2,GTF2H3,TRIM13,TCEB3,SMARCA4,RSF1,NELFA,SUPT5H,POLR2A,SMARCB1,ELL,SNW1,SUPT4H1,CCNT1,CDK9,GTF2H1,NCBP2,TRIM14 |
| 1.013e-02 | -4.59 | RPO21 (DNA-directed RNA polymerase II core subunit RPO21) | protein interactions | 851415 | 4 | 3 | 16036 | 2270 |
SSU72,UBC,NEDD4 |
| 1.013e-02 | -4.59 | EPHA10 (EPH receptor A10) | protein interactions | 284656 | 4 | 3 | 16036 | 2270 |
BANP,CAMK2D,TFCP2 |
| 1.013e-02 | -4.59 | NAT8L (N-acetyltransferase 8-like (GCN5-related, putative)) | protein interactions | 339983 | 4 | 3 | 16036 | 2270 |
FLNC,TSPAN5,KIAA0232 |
| 1.013e-02 | -4.59 | APOBEC3F (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F) | protein interactions | 200316 | 4 | 3 | 16036 | 2270 |
ACD,BMI1,TRA2A |
| 1.013e-02 | -4.59 | IFT22 (intraflagellar transport 22) | protein interactions | 64792 | 4 | 3 | 16036 | 2270 |
IFT57,RBM33,ARL13B |
| 1.013e-02 | -4.59 | ACSS2 (acyl-CoA synthetase short-chain family member 2) | protein interactions | 55902 | 4 | 3 | 16036 | 2270 |
CAD,MAT2A,WARS |
| 1.013e-02 | -4.59 | ced-3 (Cell death protein 3 subunit 1) | protein interactions | 178272 | 4 | 3 | 16036 | 2270 |
NOL3,CRADD,CASP8AP2 |
| 1.013e-02 | -4.59 | ZNF200 (zinc finger protein 200) | protein interactions | 7752 | 4 | 3 | 16036 | 2270 |
SKIL,FAM208B,PPARGC1B |
| 1.013e-02 | -4.59 | WDR46 (WD repeat domain 46) | protein interactions | 9277 | 4 | 3 | 16036 | 2270 |
RNF2,SIRT7,PUM3 |
| 1.013e-02 | -4.59 | ADPRH (ADP-ribosylarginine hydrolase) | protein interactions | 141 | 4 | 3 | 16036 | 2270 |
ACD,TFCP2,SRPK2 |
| 1.013e-02 | -4.59 | C14orf169 (chromosome 14 open reading frame 169) | protein interactions | 79697 | 4 | 3 | 16036 | 2270 |
TRRAP,MYC,USP42 |
| 1.013e-02 | -4.59 | MORC1 (MORC family CW-type zinc finger 1) | protein interactions | 27136 | 4 | 3 | 16036 | 2270 |
RNF40,HERC1,MORC2 |
| 1.013e-02 | -4.59 | SEMA4B (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B) | protein interactions | 10509 | 4 | 3 | 16036 | 2270 |
DLG4,PLXNB1,DCBLD2 |
| 1.013e-02 | -4.59 | Shprh (SNF2 histone linker PHD RING helicase) | protein interactions | 268281 | 4 | 3 | 16036 | 2270 |
HLTF,RAD18,POLK |
| 1.013e-02 | -4.59 | MUC16 (mucin 16, cell surface associated) | protein interactions | 94025 | 4 | 3 | 16036 | 2270 |
IGBP1,UBC,LGALS1 |
| 1.013e-02 | -4.59 | TNCATNTCCYR_UNKNOWN | MSigDB lists | TNCATNTCCYR_UNKNOWN | 127 | 26 | 17758 | 2279 |
BDNF,CHMP2A,MPI,HMBOX1,DROSHA,TSTA3,MON1A,PAX2,OPHN1,HDAC8,ZNFX1,MEN1,SYMPK,C19orf70,MTR,RDH11,TTC1,CD96,ALKBH8,INTS9,FTSJ1,CSMD3,POLR1B,C15orf41,ACTR3B,PRPF19 |
| 1.019e-02 | -4.59 | FLNA (filamin A, alpha) | protein interactions | 2316 | 167 | 35 | 16036 | 2270 |
TTN,CUL7,FN1,SIRT7,TRIO,MYH9,IKBIP,IKBKAP,PRKCA,FLNB,SH2B3,MYC,BANF1,SRRM2,DBN1,CAMKK2,SIRT6,CMIP,LGALS1,LIG4,AKAP12,CAV1,BRCA1,ISG15,RPA1,DYNC1H1,SMAD3,RANBP2,BRCA2,TP53BP1,SVIL,PFDN2,NMD3,MAP2K4,AGO3 |
| 1.020e-02 | -4.59 | HIV Transcription Elongation | REACTOME pathways | R-HSA-167169 | 43 | 12 | 8202 | 1117 |
ELL,GTF2H3,SUPT4H1,CCNT1,GTF2H2C,CDK9,TCEB3,GTF2H1,NCBP2,NELFA,SUPT5H,POLR2A |
| 1.020e-02 | -4.59 | Tat-mediated elongation of the HIV-1 transcript | REACTOME pathways | R-HSA-167246 | 43 | 12 | 8202 | 1117 |
ELL,GTF2H3,SUPT4H1,CCNT1,GTF2H2C,CDK9,TCEB3,GTF2H1,NCBP2,NELFA,SUPT5H,POLR2A |
| 1.020e-02 | -4.59 | Formation of HIV-1 elongation complex containing HIV-1 Tat | REACTOME pathways | R-HSA-167200 | 43 | 12 | 8202 | 1117 |
ELL,GTF2H3,SUPT4H1,CCNT1,GTF2H2C,CDK9,TCEB3,GTF2H1,NCBP2,NELFA,SUPT5H,POLR2A |
| 1.021e-02 | -4.58 | thyroid-carcinoma-anaplastic_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-anaplastic_carcinoma | 886 | 137 | 17775 | 2278 |
GGT1,ASCC1,CDCP1,GPBP1L1,TFIP11,SBF2,CCNL2,SEC16A,UBR5,PCDH7,RTN1,ANAPC1,SYN2,ZNF85,VPS13B,LAMA4,FLNC,DEAF1,NRAS,CUX1,NFIA,KSR2,SON,ZNF91,TCF7L1,AHNAK,TOM1L2,SH3RF1,SGSM2,GALNT10,TPM1,PTPN14,VIPR1,HERC2,EP400,JUP,TRIO,EVPL,TECTA,DDX56,SIPA1L3,ALDH18A1,SYNGAP1,IFNGR2,USP49,ZNF512B,OBSCN,MAP7D1,ZNFX1,SLC26A11,ARIH2,VAC14,TBC1D2,SPAG9,ALKBH3,KIAA0355,HIF1A,SPEN,DNAH17,ZNF430,UMPS,CNDP2,DMXL2,TRERF1,PCNT,RSL1D1,SMARCA4,ZNF83,TNKS1BP1,ARMC6,CAMTA2,FMNL1,GLYR1,TTC3,ITGAX,MET,KMT2A,ZC3H3,LSM10,LYST,KDM3B,SSFA2,KIRREL2,CCNDBP1,MED16,DSP,ERC1,RAB10,HLA-DMA,TAF2,SIX5,ZNF557,ITGA2,HOXA3,TRMT2A,IFT140,MDN1,BRD9,TROVE2,SMG1,ATXN7L2,BRAF,DNAJA4,UTP14A,C10orf2,MRI1,MLH1,CCDC7,ENOX1,POM121,NDUFV1,HAS3,DSG2,LTN1,UPF2,AMOT,MBTPS2,SLC6A16,KDM6B,ARHGAP39,WDR18,ADSL,TBRG4,MEN1,PIK3CB,POLR3A,SMPDL3B,RPA1,ZNF708,GPC2,HELZ,AGTPBP1,BCAS3,AEN,ZRANB2,NFKBIB,MTMR1 |
| 1.021e-02 | -4.58 | anaplastic_carcinoma | COSMIC cancer mutations | anaplastic_carcinoma | 886 | 137 | 17775 | 2278 |
GGT1,ASCC1,CDCP1,GPBP1L1,TFIP11,SBF2,CCNL2,SEC16A,UBR5,PCDH7,RTN1,ANAPC1,SYN2,ZNF85,VPS13B,LAMA4,FLNC,DEAF1,NRAS,NFIA,CUX1,KSR2,SON,ZNF91,TCF7L1,AHNAK,TOM1L2,SH3RF1,SGSM2,GALNT10,TPM1,PTPN14,VIPR1,HERC2,EP400,JUP,TRIO,EVPL,TECTA,DDX56,SIPA1L3,ALDH18A1,SYNGAP1,IFNGR2,USP49,ZNF512B,OBSCN,MAP7D1,ZNFX1,SLC26A11,ARIH2,VAC14,TBC1D2,SPAG9,ALKBH3,HIF1A,KIAA0355,SPEN,DNAH17,ZNF430,UMPS,CNDP2,DMXL2,TRERF1,PCNT,RSL1D1,SMARCA4,ZNF83,TNKS1BP1,ARMC6,CAMTA2,FMNL1,GLYR1,TTC3,ITGAX,MET,KMT2A,LSM10,ZC3H3,LYST,KDM3B,SSFA2,KIRREL2,MED16,CCNDBP1,DSP,ERC1,RAB10,HLA-DMA,TAF2,SIX5,ZNF557,ITGA2,HOXA3,TRMT2A,IFT140,MDN1,BRD9,TROVE2,SMG1,ATXN7L2,DNAJA4,BRAF,UTP14A,C10orf2,MRI1,MLH1,CCDC7,ENOX1,POM121,NDUFV1,HAS3,DSG2,LTN1,UPF2,AMOT,MBTPS2,SLC6A16,KDM6B,WDR18,ARHGAP39,TBRG4,ADSL,MEN1,PIK3CB,POLR3A,SMPDL3B,RPA1,ZNF708,HELZ,GPC2,AGTPBP1,BCAS3,AEN,ZRANB2,NFKBIB,MTMR1 |
| 1.022e-02 | -4.58 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 190 | 36 | 17758 | 2279 |
CLK1,FAM189B,ID2,UBTD2,PCYOX1L,DST,SRSF2,MBD2,NDRG4,ME1,PFKFB4,ZCCHC14,ITPA,FOXN3,AKAP12,ARHGEF12,PRDM1,PALLD,USP36,RERE,BSN,ANXA1,PES1,GLS,UBTF,CAMK2D,SMARCC1,INSIG1,SERINC1,PAM,RNF138,RWDD2B,KLHDC4,SH3PXD2A,TSPAN5,SPOCK2 |
| 1.022e-02 | -4.58 | GSE17721_CTRL_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_4H_BMDM_UP | 190 | 36 | 17758 | 2279 |
TNNC1,NCOR2,AUH,TNFRSF21,RFX1,SMARCA4,NUP43,PIP4K2A,ADH5,RAP1A,KDELC1,CTR9,POLE3,TSPAN14,TMEM14C,RABEPK,KLRD1,ACADS,VOPP1,CPT1A,ABCF1,VAC14,ZBTB25,STOML2,RPA1,MGAT2,HLA-DMA,ELP2,ADNP,DUSP19,ATM,ARC,HMBS,ECHDC1,SYNPO,MAP2K4 |
| 1.022e-02 | -4.58 | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | 190 | 36 | 17758 | 2279 |
STX8,UBN1,GPBP1L1,C10orf2,TRPM6,DLGAP4,CCNL2,INPP1,SUB1,HR,ATP5G2,NCKIPSD,GREB1,FHIT,RPL22L1,DENND1A,MS4A15,SOBP,FAM127A,EVL,AP4S1,RREB1,STAMBP,KCNMA1,PLEKHM3,MEGF11,COTL1,C8orf33,SON,TCF7L1,ZBTB8OS,CLEC16A,RLTPR,RNF138,TNFRSF1A,TBXA2R |
| 1.022e-02 | -4.58 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 190 | 36 | 17758 | 2279 |
COMMD10,ASH1L,SPATS2L,RPS6KA5,TOM1L1,GART,PUS3,EIF2S2,ZNF586,ASAP1,TANK,GTF2H1,AHCYL1,CCDC121,VCL,ACSL5,CHD9,KIAA0586,PSMA1,ARHGEF12,C11orf49,SON,KLF6,FOXC1,SPOP,OSBPL1A,KPNA3,SERF2,ARL6IP5,STX18,MSH3,ABCC3,RBPJ,ANXA2,ADK,LPP |
| 1.022e-02 | -4.58 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | 190 | 36 | 17758 | 2279 |
ARHGAP26,BCKDK,FEZ2,SYT17,SESTD1,B4GALT5,TRAK1,DENND3,NAMPT,SH2B3,RTN1,HVCN1,CCDC50,PTGS1,ZNF710,VCL,LYST,MPST,SAP30,TBC1D8,PEA15,PDE4A,PTPN12,UBE2E1,HERPUD1,RAB10,PGD,RHOU,CAT,MTHFD2,PDLIM1,SNAP23,CFD,GALNT10,RNF130,USP15 |
| 1.022e-02 | -4.58 | GSE27786_LSK_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LSK_VS_ERYTHROBLAST_UP | 190 | 36 | 17758 | 2279 |
IMMP2L,MYCBP2,BCKDK,PGPEP1,BTBD2,PPHLN1,SF3A3,TTI1,PIBF1,MGA,KDM1A,FRRS1,CAD,EXOC1,COPS3,IKBKB,PPM1K,MTHFD1,TSHZ1,SIK3,FAM172A,SIGMAR1,NOL8,SCFD2,PACRGL,MEX3B,SUPT5H,ATP8B2,GUF1,DUS3L,PDLIM1,CHD3,CDK9,ZNF32,SCARB1,ZBTB24 |
| 1.022e-02 | -4.58 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN | 190 | 36 | 17758 | 2279 |
TTC27,B4GALT5,RIPK1,CHCHD10,PRKCH,RNF141,DECR1,PHKA1,CBR4,GPATCH1,PLEKHA2,PPA1,LONP1,MTHFD1,WDR61,PSAT1,SLC38A1,TYW1,ELP3,PEAR1,FOXRED1,BAZ1A,PWP1,RARS,DAGLB,ACP1,C7orf50,HEATR1,HMBS,PUS1,TSEN2,SETD6,NOLC1,PPIL3,FGFBP3,RAB30 |
| 1.022e-02 | -4.58 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP | 190 | 36 | 17758 | 2279 |
SART1,RWDD1,WDR74,PRPF31,UBN1,SAFB2,MFSD10,AMBRA1,ATP5G2,CFDP1,BANF1,COPS7B,CORO1A,TSPAN14,HTRA2,HNRNPM,PRPF19,CDC37,ZBTB17,ARHGAP17,TSTA3,LSM12,WDR18,ZNF512B,MARCKSL1,IMPDH2,ATP5D,PAF1,LSM14A,CDK9,TAF4,H2AFX,CCDC85B,PFDN2,NFKBIB,LRRC41 |
| 1.025e-02 | -4.58 | Znf_U1 | interpro domains | IPR003604 | 25 | 8 | 18293 | 2341 |
RBM20,ZNF622,ZFHX3,ZNF346,ZMAT2,ZNF407,ZMAT3,ZFHX2 |
| 1.027e-02 | -4.58 | MODULE_36 | MSigDB lists | MODULE_36 | 152 | 30 | 17758 | 2279 |
PHF3,STX8,CELSR3,ZNF821,TSN,TRAK1,SLC25A12,SLC35D1,PIBF1,CYB5B,SYMPK,UBE2E1,BAZ1A,FLAD1,SURF2,PVRL3,SPEN,ACOX1,ORC5,LPIN2,ALKBH1,GTF2H1,FKBP5,UPF2,KIAA0922,HRG,RNF114,COG5,ZNF646,MORC2 |
| 1.028e-02 | -4.58 | AAAGGAT,MIR-501 | MSigDB lists | AAAGGAT,MIR-501 | 121 | 25 | 17758 | 2279 |
PDK1,CLK1,WDFY3,ZMYM5,SATB2,RSBN1,PNN,SOX4,SYNJ1,PLXNB1,RPGRIP1L,LPIN1,PHF6,PRKCE,SRSF2,UBAP1,H2AFX,RDX,SENP3,NFASC,ERRFI1,NR2F2,CLK2,MEF2C,MYB |
| 1.028e-02 | -4.58 | RODRIGUES_DCC_TARGETS_DN | MSigDB lists | RODRIGUES_DCC_TARGETS_DN | 121 | 25 | 17758 | 2279 |
KDM5B,MYO10,PRKAB2,FOXN3,PTPRG,FOSL2,TGFB2,FOXP1,KLF6,ECH1,NR2F1,IQGAP2,GNG2,CAT,BICD1,GADD45A,UBR1,ACOX1,TANK,TBX3,RIOK3,HOXA3,NRP1,CD44,MID1 |
| 1.031e-02 | -4.58 | WW_dom | interpro domains | IPR001202 | 51 | 13 | 18293 | 2341 |
CEP164,PRPF40B,APBB3,SETD2,ARHGAP39,WAC,PQBP1,WWC1,ARHGAP12,MAGI1,ARHGAP27,NEDD4,IQGAP2 |
| 1.032e-02 | -4.57 | GAVIN_FOXP3_TARGETS_CLUSTER_P7 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P7 | 85 | 19 | 17758 | 2279 |
KLRD1,WLS,AGPAT4,ADAMTS6,ENC1,ST3GAL6,AHCYL2,ANXA1,DST,MSRA,ECM1,IKZF4,RABGAP1L,HIPK2,GSTA4,PRF1,TMEM158,LYST,NT5E |
| 1.032e-02 | -4.57 | heme biosynthetic process | biological process | GO:0006783 | 20 | 7 | 16441 | 2138 |
HMBS,ALAD,COX10,FXN,TMEM14C,CPOX,UROD |
| 1.032e-02 | -4.57 | error-prone translesion synthesis | biological process | GO:0042276 | 20 | 7 | 16441 | 2138 |
RFC4,RFC3,POLE2,POLK,MAD2L2,UBC,RPA1 |
| 1.032e-02 | -4.57 | ARM-like | interpro domains | IPR011989 | 210 | 39 | 18293 | 2341 |
RTTN,JUP,NF1,PIK3R4,MON2,AP1B1,TTI1,ARID1B,TMCO6,CTNNBL1,ARMC6,INTS7,ARMC5,PDS5B,TNPO3,SPAG6,IPO11,IFRD1,RANBP6,C1orf228,WDFY3,TANGO6,XPO5,AP4B1,PACRGL,RAP1GDS1,SYMPK,VAC14,PUM3,ARMC3,ARMC4,KPNA1,TRRAP,KPNA3,AGTPBP1,SIL1,HEATR1,XPO6,IPO4 |
| 1.034e-02 | -4.57 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | 171 | 33 | 17758 | 2279 |
SLC12A7,PTP4A1,TTN,ITPRIP,VTI1A,ST7L,FAM8A1,DDIT4,IQGAP2,FHIT,PERP,DIS3L2,CHD9,PTPRM,RAP1GAP2,ARRDC3,MEF2D,ENC1,PLCXD2,ZBTB25,ZFAND3,NAP1L5,SKIL,AHNAK,PXDN,ZDHHC11,GADD45A,DCXR,AGTPBP1,KLF4,EXOC4,SMYD3,LPP |
| 1.035e-02 | -4.57 | mucoepidermoid_carcinoma | COSMIC cancer mutations | mucoepidermoid_carcinoma | 97 | 21 | 17775 | 2278 |
HMGA2,BRAF,NRAS,METTL23,MKS1,DSP,MFSD10,MTUS1,ZFP62,DST,DHX33,FAT1,WDR73,TMEM99,LTN1,ANXA2,GEMIN4,MET,PDCD11,KMT2A,MAP2K4 |
| 1.036e-02 | -4.57 | PETROVA_PROX1_TARGETS_DN | MSigDB lists | PETROVA_PROX1_TARGETS_DN | 62 | 15 | 17758 | 2279 |
SLC38A6,KRT7,TNFRSF21,VCAN,ARL6IP5,TANK,AHNAK2,MMP14,TRIM22,NRP1,TPM1,CD44,BMP6,PRKACB,IGF2BP3 |
| 1.040e-02 | -4.57 | Response to fenofibrate(PMID:22890011) | GWAS genes | Response to fenofibrate(PMID:22890011) | 6 | 4 | 2389 | 419 |
PDE10A,PPARGC1B,JMJD1C,AHCYL2 |
| 1.040e-02 | -4.57 | Type 2 diabetes(PMID:17463246) | GWAS genes | Type 2 diabetes(PMID:17463246) | 6 | 4 | 2389 | 419 |
CDKAL1,IGF2BP2,PPARG,TCF7L2 |
| 1.042e-02 | -4.56 | BIOCARTA_STRESS_PATHWAY | MSigDB lists | BIOCARTA_STRESS_PATHWAY | 25 | 8 | 17758 | 2279 |
CRADD,TANK,IKBKB,TNFRSF1A,RIPK1,MAP3K14,MAP2K4,MAP2K3 |
| 1.042e-02 | -4.56 | OUTER_MEMBRANE | MSigDB lists | OUTER_MEMBRANE | 25 | 8 | 17758 | 2279 |
RETSAT,MCL1,FIS1,OPA1,RHOT2,DHCR7,TOMM34,MFN2 |
| 1.044e-02 | -4.56 | bone-rib-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-rib-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 165 | 32 | 17775 | 2278 |
HERC2,ZNF786,BRAF,FANCD2,DBF4,DNAH1,PAG1,KRI1,VPS18,CNST,KDM2A,GRIN2C,SHF,FBL,FBXO31,MAML3,FAM71E1,DPF3,AP4B1,OBSCN,PNN,KMT2C,MTR,CAT,HSPBAP1,FAT1,ITGA2,CRCP,MYOM2,MBD6,METTL2B,KDM4C |
| 1.045e-02 | -4.56 | KEGG_BASAL_TRANSCRIPTION_FACTORS | MSigDB lists | KEGG_BASAL_TRANSCRIPTION_FACTORS | 35 | 10 | 17758 | 2279 |
TAF2,GTF2H3,GTF2A1,TAF1,TAF4,TBPL1,GTF2H1,GTF2IRD1,TAF12,TAF9B |
| 1.045e-02 | -4.56 | CHROMATIN | MSigDB lists | CHROMATIN | 35 | 10 | 17758 | 2279 |
SUV39H2,ATRX,POLA1,PAM,TIMELESS,APTX,RAN,MCM2,FOXC1,TMPO |
| 1.045e-02 | -4.56 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | MSigDB lists | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | 35 | 10 | 17758 | 2279 |
RFC4,MCM6,RFC3,MCM10,MCM5,ORC5,DBF4,ATRIP,MCM2,RPA1 |
| 1.045e-02 | -4.56 | LOPEZ_TRANSLATION_VIA_FN1_SIGNALING | MSigDB lists | LOPEZ_TRANSLATION_VIA_FN1_SIGNALING | 35 | 10 | 17758 | 2279 |
EFNB2,TRIO,TNPO3,MCL1,SOX4,TGFBR2,EIF5B,MMP16,PDE3A,SRPK2 |
| 1.047e-02 | -4.56 | MODULE_321 | MSigDB lists | MODULE_321 | 109 | 23 | 17758 | 2279 |
PXN,TRIP6,LPCAT2,WLS,LDHA,MYH9,FERMT2,PLOD1,LRRC8A,SPATS2L,FOSL2,TGFBR2,KLF6,DCBLD2,SHC1,NEK6,S100A10,MYC,ADAM9,ANXA5,FKBP5,CD44,VCL |
| 1.047e-02 | -4.56 | PROTEIN_TARGETING | MSigDB lists | PROTEIN_TARGETING | 109 | 23 | 17758 | 2279 |
TRIP6,NF1,TRAK1,XPO7,NUP214,NOP58,RPAIN,RERE,MFN2,PEX1,TIMM44,TAMM41,SMAD3,PEX7,RANBP2,KPNA1,KPNA3,TIMM17A,NCKIPSD,PEX13,TOMM34,XPO6,CDC37 |
| 1.049e-02 | -4.56 | SPAG9 (sperm associated antigen 9) | protein interactions | 9043 | 32 | 10 | 16036 | 2270 |
ABL1,SPAG9,TP53BP1,MYC,SIRT7,EIF4A2,BRCC3,NOLC1,MAP2K4,MAP2K3 |
| 1.049e-02 | -4.56 | ATXN2L (ataxin 2-like) | protein interactions | 11273 | 32 | 10 | 16036 | 2270 |
SMAD3,LSM12,KHDRBS1,SIRT7,ATXN1,FUS,BMI1,PABPC1,ISG15,PABPC4 |
| 1.049e-02 | -4.56 | Ddb1 (damage specific DNA binding protein 1) | protein interactions | 13194 | 32 | 10 | 16036 | 2270 |
ABL1,CUL4A,COPS4,COPS5,COPS3,COPS7B,COPS6,PHGDH,AMBRA1,NUDC |
| 1.051e-02 | -4.56 | ATTACAT,MIR-380-3P | MSigDB lists | ATTACAT,MIR-380-3P | 97 | 21 | 17758 | 2279 |
BDNF,LIN28B,BIRC6,USP49,B4GALT5,WDR26,BCOR,SNAP25,MBNL1,NAMPT,HTR7,C6orf141,ADAT2,LTN1,RBM26,APAF1,CNOT4,BMI1,C15orf41,MEF2C,TRIM36 |
| 1.051e-02 | -4.56 | CLK2 (CDC like kinase 2) | protein interactions | 1196 | 67 | 17 | 16036 | 2270 |
ZCCHC8,SKIV2L2,TRA2A,SETD2,PPHLN1,PNN,BRCA1,SON,UBL5,ATRIP,TNPO3,WDR33,FIP1L1,PABPC1,HNRNPM,SRPK2,CLK2 |
| 1.053e-02 | -4.55 | CDC5L (cell division cycle 5-like) | protein interactions | 988 | 179 | 37 | 16036 | 2270 |
CUL7,MCM10,UTP14A,PLRG1,TRIO,TRAK1,SCAF8,KDM1A,SFI1,SFR1,DST,EXOC1,SNW1,SUB1,SRSF2,EIF2S2,RPS16,CTNNBL1,BCAS2,KANSL1,MCM5,SRRM2,FTSJ3,PRPF19,SF3A1,PMS1,TRA2A,ZC3H18,WDR18,WWC1,SON,RPA1,DYNC1H1,HNRNPR,ORC5,FUS,SRP14 |
| 1.053e-02 | -4.55 | Heme biosynthesis | REACTOME pathways | R-HSA-189451 | 11 | 5 | 8202 | 1117 |
HMBS,ALAD,COX10,CPOX,UROD |
| 1.053e-02 | -4.55 | Purine ribonucleoside monophosphate biosynthesis | REACTOME pathways | R-HSA-73817 | 11 | 5 | 8202 | 1117 |
ADSL,IMPDH2,GART,PPAT,ATIC |
| 1.054e-02 | -4.55 | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 30 | 9 | 17775 | 2278 |
BRCA2,BRAF,NRAS,NF1,ATM,MLH1,BRCA1,MET,MAP2K4 |
| 1.054e-02 | -4.55 | ZHU_CMV_8_HR_DN | MSigDB lists | ZHU_CMV_8_HR_DN | 51 | 13 | 17758 | 2279 |
ANAPC1,TP53BP1,TFPI,TNFRSF1A,MYH9,ID2,ZFP36L1,BMP4,RUNX1,NR2F2,AARS,TCF7L2,DDIT4 |
| 1.055e-02 | -4.55 | ribonuclease activity | molecular function | GO:0004540 | 95 | 21 | 16491 | 2164 |
EXOSC2,DROSHA,APEX1,AGO2,TSN,POP5,RNASEH2B,PARN,EDC3,EXO1,POP1,RPP30,TOE1,ERI1,CNOT6,EXOSC4,CPSF3,TSEN2,ERI3,NOCT,DIS3L2 |
| 1.056e-02 | -4.55 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_UP | 184 | 35 | 17758 | 2279 |
CYLD,MAP2K5,ACTR3,NDUFB5,C14orf159,RIPK1,RNF43,C11orf54,DDIT4,NDUFB3,ARHGAP18,PXK,CWF19L2,C12orf4,TRIM13,KIAA1143,EXOC6B,AP4B1,ATOX1,LGALS1,FRA10AC1,COTL1,RABAC1,CA5B,CHCHD6,MMAA,ATP5D,COQ9,SDCCAG8,VPS37B,RIOK3,DNAJC12,PDLIM5,MTMR1,COG5 |
| 1.056e-02 | -4.55 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN | 184 | 35 | 17758 | 2279 |
ZNF254,EGR1,ABCA7,NOP56,PPFIBP1,GPATCH1,GEMIN4,POLR1E,LYST,USE1,DPF3,APEX1,SKAP2,TXLNG,RAB7A,RFX2,ATXN1,SATB2,TRIM37,UBR4,TJAP1,TMCO1,ADNP,ZCCHC6,NCBP2,FKBP5,MYOM2,APAF1,TAF12,PREPL,PDLIM5,NOLC1,ARHGAP10,SYNPO,GPATCH4 |
| 1.056e-02 | -4.55 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | 184 | 35 | 17758 | 2279 |
CHST11,B4GALT5,SLC2A1,MRPL10,SMAD7,SPATS2L,GYG1,BHLHE40,MAN1A1,SH2B3,JAZF1,LPCAT1,PRF1,SAP30,KLRD1,PHLDB2,SESN2,KATNAL1,RAP1GAP2,ELP3,TPM4,ATXN1,TTYH2,ZDHHC14,KLF6,PLCXD2,SMAD3,RHOU,AHNAK,TTC38,DNAJC1,PAM,ANXA2,PTP4A2,LPP |
| 1.056e-02 | -4.55 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | 184 | 35 | 17758 | 2279 |
DCTN3,SCAMP3,PPIL1,SLC29A1,ABHD6,GFM2,MAD2L2,ADH5,RNF141,FARSA,RPS16,S100A10,ATG3,COPS3,ATIC,SELT,RAN,POLE3,PRPS1,ATP6V0D1,RFC4,RFC3,WDR61,CDK4,PSMG1,CCNDBP1,DCUN1D5,CLNS1A,NEU1,WARS,GNAI1,STOML2,PGD,POLE2,KIAA0196 |
| 1.056e-02 | -4.55 | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_UP | 184 | 35 | 17758 | 2279 |
ABCA3,RFX1,RSL1D1,RNF24,LIAS,SSBP2,CAD,PDZD2,ZFP37,SYNJ2,SLC27A5,SLC35C2,FBL,POLR1E,NT5E,MAML3,ADARB1,FGF9,IL11RA,FOXN3,PRDM16,CUX1,SERGEF,EIF3H,RERE,DOT1L,ANXA1,ZDHHC11,DNAH17,RNF130,MACROD1,ZMAT3,SLC16A10,SGSM3,SLC43A1 |
| 1.057e-02 | -4.55 | Nucleotide Excision Repair | REACTOME pathways | R-HSA-5696398 | 109 | 24 | 8202 | 1117 |
USP7,GTF2H3,RFC4,RFC3,CUL4A,XPC,GTF2H2C,POLK,PARP2,SUMO3,UBC,POLR2A,RPA1,ELL,COPS4,POLE2,COPS3,COPS5,GTF2H1,RNF111,COPS7B,NFRKB,COPS6,PRPF19 |
| 1.058e-02 | -4.55 | DNAJB1 (DnaJ (Hsp40) homolog, subfamily B, member 1) | protein interactions | 3337 | 83 | 20 | 16036 | 2270 |
NRAS,FN1,ANK2,ADSL,BRCA1,XPO7,RNASEH2B,HSPA1A,UBC,ISG15,AMBRA1,SNCA,HIF1A,PPID,VPS37B,ETF1,BAG1,NUDC,CDC37,RPS6KB2 |
| 1.058e-02 | -4.55 | SSB (Sjogren syndrome antigen B (autoantigen La)) | protein interactions | 6741 | 83 | 20 | 16036 | 2270 |
NIFK,FN1,WDR74,ANKMY2,SIRT7,NAT10,MYH9,CSNK2A1,SAFB2,UBC,NOP56,SURF2,COPS5,CUL2,H2AFX,RNF2,POLR1C,BMI1,TROVE2,CDC37 |
| 1.060e-02 | -4.55 | nuclear hormone receptor binding | molecular function | GO:0035257 | 143 | 29 | 16491 | 2164 |
PRAME,TRIP6,JUP,PPARG,PPARGC1B,JMJD1C,HSD17B10,SMARCA4,SMARCD3,MED16,BRCA1,OASL,FOXP1,KDM1A,TCF7L2,VDR,SNW1,NSD1,HR,HIF1A,PPID,BUD31,BCAS3,MED24,FUS,RAN,NCOR1,NRIP1,KDM4C |
| 1.061e-02 | -4.55 | cellular amino acid biosynthetic process | biological process | GO:0008652 | 90 | 20 | 16441 | 2138 |
SEPHS2,GGT1,PSAT1,MRI1,PLOD1,MTHFD1L,PHGDH,MTR,PYCR1,GLS,CAD,MTHFD2,ASNS,GART,PYCRL,ATIC,SHMT2,ALDH18A1,MTHFD2L,MTHFD1 |
| 1.062e-02 | -4.54 | protein acetyltransferase complex | cellular component | GO:0031248 | 98 | 21 | 17570 | 2233 |
KAT8,NAA38,WDR75,EP400,ELP3,SUPT20H,IKBKAP,TAF9B,TADA3,TAF2,ATXN7,TRRAP,ELP2,KANSL1,TAF4,UBAP2L,POLE3,TAF12,YEATS2,NAA35,KAT6A |
| 1.062e-02 | -4.54 | acetyltransferase complex | cellular component | GO:1902493 | 98 | 21 | 17570 | 2233 |
KAT8,NAA38,WDR75,EP400,ELP3,SUPT20H,IKBKAP,TAF9B,TADA3,TAF2,ATXN7,TRRAP,ELP2,KANSL1,TAF4,UBAP2L,POLE3,TAF12,YEATS2,NAA35,KAT6A |
| 1.063e-02 | -4.54 | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP | MSigDB lists | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP | 30 | 9 | 17758 | 2279 |
SLC39A14,RFC4,SLK,HSPB8,SNX24,SLC16A1,SLC35F2,MLLT10,ZNF629 |
| 1.063e-02 | -4.54 | CACGTTT,MIR-302A | MSigDB lists | CACGTTT,MIR-302A | 30 | 9 | 17758 | 2279 |
SOBP,UCHL5,LEMD3,CUL2,ARRDC3,LRRC8A,NBEA,SSBP2,IGF2BP1 |
| 1.064e-02 | -4.54 | PUJANA_XPRSS_INT_NETWORK | MSigDB lists | PUJANA_XPRSS_INT_NETWORK | 165 | 32 | 17758 | 2279 |
MCM6,TCF3,CSNK2A1,SSBP2,RNASEH2B,CAD,MCM5,COPS3,TIMELESS,KIAA0922,PRPS1,TOP1,TMPO,RFC4,RFC3,USP49,POLA1,BRCA1,PNN,MCM2,EIF3H,MAT2A,RPA1,CHAF1A,SLC7A1,SEC31A,RBBP8,BRCA2,ZNF330,ATM,PRPF4,BLMH |
| 1.066e-02 | -4.54 | DDX17 (DEAD (Asp-Glu-Ala-Asp) box helicase 17) | protein interactions | 10521 | 133 | 29 | 16036 | 2270 |
CUL7,FN1,TXLNG,KHDRBS1,SMARCAD1,TCF3,CSNK2A1,MBNL1,HNRNPA3,UBC,ISG15,SBDS,RPA1,RANBP2,P3H1,SYNCRIP,YLPM1,MYC,HNRNPH3,ATXN2,COPS5,CUL2,FUS,FBL,RTFDC1,TOP1,CDC37,SF3A1,RPS6KB2 |
| 1.066e-02 | -4.54 | V$ERR1_Q2 | MSigDB lists | V$ERR1_Q2 | 249 | 45 | 17758 | 2279 |
ASCC1,ATP6V1A,KIF5A,CSNK2A1,SSR4,BZW2,PCDH7,ANKRD13A,NAV1,PHF5A,CACNB2,RNF2,CHD2,KDM5C,VCL,FBXL19,SRPK2,MSI2,TIMM8B,FGF9,RREB1,WDFY3,AOC2,KDM5A,IDH3G,JMJD1C,GDPD1,KIAA0586,VSNL1,WWC1,OBSCN,KCNH2,PHF6,YTHDF2,ATAD5,SLC30A3,SPAG9,HOXA3,SOCS4,ADAM9,DIRAS1,TNRC6A,ATXN7L2,KAT6A,MEF2C |
| 1.071e-02 | -4.54 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | 197 | 37 | 17758 | 2279 |
ACTG1,SLK,DBF4,PLA2G12A,IGF2BP2,SIRT2,SPATS2,ST3GAL6,TIMM10,NEDD4,ANXA10,ZNF239,CHD7,SUB1,SLC7A11,CLDND1,RAN,PRF1,SERBP1,PTPRK,BDNF,COL5A2,SKAP2,CPOX,LDHA,PRDM1,HERPUD1,SPOP,GNG2,LSS,ALAD,IKZF4,VPS37B,SURF1,RBPJ,ZMAT3,LPP |
| 1.072e-02 | -4.54 | purine ribonucleoside metabolic process | biological process | GO:0046128 | 272 | 49 | 16441 | 2138 |
NDUFA5,AK2,SULT1C2,ATP6V1A,MRI1,NDUFB5,OLA1,APRT,CHCHD10,COX10,HSPA1A,NDUFS7,AHCYL2,NDUFB3,AMPD3,NDUFV1,ENTPD5,ATP5G2,PPCDC,MYH3,NDUFA6,AHCYL1,FXN,PRPS1,NT5E,HMGCR,MCEE,PFKFB4,BDNF,LDHA,SULT4A1,DLG4,ATP6V0A1,ADSL,IMPDH2,MAT2A,HSPA1B,SNCA,STOML2,ATP5D,HPRT1,NME7,COQ9,PEMT,HK2,SURF1,NDUFS5,BPNT1,ADK |
| 1.078e-02 | -4.53 | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | 210 | 39 | 17758 | 2279 |
PTP4A1,ITPRIP,C16orf52,SLC2A1,SMAD7,ZFP36L1,RCAN1,BHLHE40,FOSL2,DENND3,JAG1,PPFIBP1,JOSD1,CLDND1,KDM6B,PHLDB2,DNMBP,TLE3,GPCPD1,VSNL1,ATXN1,WWC1,FERMT2,MCL1,ARL5B,MBNL2,ZC3H12A,GATA6,KLF4,PER1,ITGA2,CSRNP1,PURB,DPP4,SEMA3C,FKBP5,RUNX1,HRH1,ZSWIM6 |
| 1.078e-02 | -4.53 | WDR3 (WD repeat domain 3) | protein interactions | 10885 | 23 | 8 | 16036 | 2270 |
WDR36,CUL7,DDX18,PDE10A,SIRT7,PUS1,USP36,RPA1 |
| 1.078e-02 | -4.53 | RABEP2 (rabaptin, RAB GTPase binding effector protein 2) | protein interactions | 79874 | 23 | 8 | 16036 | 2270 |
IFT57,SPAG9,HNRNPR,WDHD1,BRCC3,NOLC1,RABEP1,UBC |
| 1.078e-02 | -4.53 | ELL (elongation factor RNA polymerase II) | protein interactions | 8178 | 23 | 8 | 16036 | 2270 |
USPL1,CDK9,ICE2,SIRT2,MCM2,KMT2A,POLR2A,UBC |
| 1.078e-02 | -4.53 | NIP7 (NIP7, nucleolar pre-rRNA processing protein) | protein interactions | 51388 | 23 | 8 | 16036 | 2270 |
PES1,DDX24,DDX18,GLTSCR2,NOL8,CEBPZ,RBM28,ZC3H3 |
| 1.078e-02 | -4.53 | PELI1 (pellino E3 ubiquitin protein ligase 1) | protein interactions | 57162 | 23 | 8 | 16036 | 2270 |
DEAF1,IKBKB,IRAK2,RIPK1,UBC,VAC14,TRIP13,SRPK2 |
| 1.079e-02 | -4.53 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 974 | 151 | 16441 | 2138 |
LUZP1,ACTG1,WDR74,PPARGC1B,MFGE8,CACNA1H,MKS1,ENAH,PRKCA,NLE1,SKI,ECM1,XRCC2,MYH3,HRG,PRKACB,SRPK2,DEAF1,FMNL3,WLS,PTPRM,TMEM216,CAV1,MTHFD1L,SOX4,TCTN1,CCDC28B,KIF16B,PAF1,SKIL,DYRK1B,GATA6,E2F4,BBIP1,SEMA3C,CCNB1IP1,NRP1,TPM1,PTPN14,MEF2C,EFNB2,TTN,IFT57,FN1,CELSR1,PAX2,TRIM15,ZIC2,TGFBR2,DNAH1,CDC73,CEP164,FKBP1A,MCAM,CEP290,ATXN2,CTR9,WNT16,MFAP2,ATP6V0D1,ANGPT2,MTHFD1,SETD2,RDH10,KIAA0586,SMARCD3,OBSCN,ARID1A,ONECUT2,ANGPTL4,PALB2,HIF1A,LEMD3,SDCCAG8,TBPL1,SH3PXD2A,FNBP1L,HS2ST1,ID1,DLL4,PCNT,CELSR3,MMRN2,PAFAH1B1,C16orf45,MYH9,PIBF1,RPGRIP1L,JAG1,SHC1,MMP14,CCDC40,PERP,WDPCP,GRHL3,MEGF11,FGFR1,WARS,ZC3H12A,ARMC4,SMAD3,IFT81,MSX2,KLF4,HIPK2,ARL13B,ITGA2,HOXA3,IFT140,NFASC,ANXA2,LAMA5,HMGA2,UNC13D,JMJD6,SEMA3E,LIAS,CEP126,TGFB2,NEBL,DYNC2H1,PKNOX1,FER1L5,KDM6B,SLC40A1,FGF9,MSX1,TTLL5,CEP83,FGF2,FZD3,CCDC113,PTK2,PDE3B,FOXC1,PIK3CB,MFN2,DKK1,MKX,TMEM237,WDR35,HERC1,AGTPBP1,TBX3,BCAS3,ATM,APAF1,RBPJ,BMP4,ITGB4,STK4 |
| 1.083e-02 | -4.53 | 1-phosphatidylinositol binding | molecular function | GO:0005545 | 20 | 7 | 16491 | 2164 |
SCARB1,WDFY3,SYT1,ZFYVE1,PLEKHA4,EEA1,SESTD1 |
| 1.088e-02 | -4.52 | RBM25 (RNA binding motif protein 25) | protein interactions | 58517 | 62 | 16 | 16036 | 2270 |
SART1,CUL7,BRD4,UTP14A,PRPF31,TRA2A,SIRT7,NFIA,JMJD6,RPA1,PRPF40B,PHF5A,SRRM2,HNRNPM,PRPF19,TOP1 |
| 1.088e-02 | -4.52 | LMO4 (LIM domain only 4) | protein interactions | 8543 | 62 | 16 | 16036 | 2270 |
ZNF675,BANP,DEAF1,PPARG,SEC24D,TFIP11,BRCA1,PITPNB,SSBP2,KIAA1958,KPNA1,RBBP8,GADD45A,VPS52,ZNF397,AMOT |
| 1.098e-02 | -4.51 | positive regulation of cellular process | biological process | GO:0048522 | 4598 | 643 | 16441 | 2138 |
PTP4A1,THOC5,CACNA1H,CSPP1,HLTF,CCNL2,SYNJ1,LPAR3,AMBRA1,NOS1AP,SKI,TOM1L1,NEK6,SREBF2,ZFHX3,PMAIP1,WIZ,ZNF148,FNIP2,HRG,FXN,CDK6,HMBOX1,NRAS,WLS,GNL3,NFIA,AKAP12,C5AR1,MCL1,SHISA5,DCUN1D5,STOML2,DDX3X,BRCA2,SUPT4H1,RAD18,FIS1,DIRAS1,RUNX1,TPM1,VASH2,P2RY11,MEF2C,BANP,EPM2AIP1,TRIP6,SLK,KHDRBS1,TRIO,SIRT7,PIK3R4,RSF1,PDCD7,CDC73,ABCA7,SH2B3,CHN1,RBM20,CNST,UBE3A,APLF,MED24,ANP32B,PRMT5,MAP3K12,PABPC1,MYB,HMGCR,PEA15,GTF2H3,BDNF,WDR61,STAG1,MYO10,RB1CC1,PRDM16,ARID5B,RYR2,ATAT1,SMARCD3,SNAP25,ARRDC4,CPT1A,TRIM37,ONECUT2,ABCF1,IRS1,TASP1,KPNA1,RPL28,FGFBP1,CDK9,CNOT6,SPRED2,DNM3,MAP2K5,ZNF516,TRERF1,PAFAH1B1,NPAS2,ACTR3,DDR2,MYH9,STAM,UBL5,HSPA1A,ABCA12,ACD,WAC,MMP14,ZC3H3,LSM10,PERP,LYST,KMT2D,STAMBP,LGALS1,ARHGEF10,MEF2D,FGFR1,TAF2,FBXL5,HLA-DMA,CDC16,NSMCE2,PEMT,HIPK2,HOXA3,RPS6KB1,BRCC3,MAPT,HMGA2,SHQ1,INSIG2,ID2,GAS6,TRIM22,IP6K2,RNASEH2B,TGFB2,PSMF1,TADA3,SNW1,UNC13A,ANXA5,ARHGAP1,ACTR3B,SAMD4A,PNMA1,SOX6,SPTAN1,DDHD1,FGF9,CEP295,LDHA,IL6R,UBE2K,FOXC1,UBC,ANXA1,RPA1,OXSR1,TRIB3,NSD1,ARID3B,STX1A,GPAM,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,KDM4C,CUL7,TRIM16,AAMDC,GPBP1L1,PPARGC1B,MFGE8,CSNK2A1,NLE1,BIRC2,HNRNPLL,MAP2K3,ABL2,ECM1,PHF5A,DHX33,NCKIPSD,XRCC2,RAN,ETV1,RBCK1,ATF4,GCNT2,MIOS,PPARG,CDK4,ANK2,HSPA5,MARCKSL1,SUMO3,BRCA1,LAMA2,KCNH2,ODC1,MLLT10,DYRK1B,HPRT1,ZNF622,TCF7L1,INSIG1,TP53BP1,PER1,E2F4,SOCS4,TNFRSF1A,RAD51B,DPP4,ADAM9,PPP3CC,DLX2,BEND6,UQCC2,C2CD5,CHMP4C,FOXO1,NKD2,MAPK8IP3,LAMTOR3,SMAD7,BARX2,TRIM15,ZIC2,RLF,ARID1B,SPIRE1,RNF40,SUB1,MLX,CEP290,MBD2,NDRG4,GTF2H1,VAPB,CTR9,ICE2,WNT16,LRSAM1,CAMKK2,LAMC1,PAXBP1,CRADD,UTP15,OBSCN,MEX3B,SUPT5H,TCF7L2,NR2F1,ATXN7,SPAG9,IRAK2,TESC,PRKAR2A,SART1,ID1,CYLD,OLFM2,NTSR1,RIPK1,PAG1,PELP1,SEMA6A,PLXNB1,KDM1A,NRF1,JAG1,GRIN2C,IKBKB,CORO1A,SPIDR,CASP10,CTC1,PRPF19,SEC24A,KAT8,EVL,DDX41,RAB7A,C1QTNF1,AKAP13,ENC1,USP36,SMAD3,SIX5,KLF4,ATG7,PUS1,PKIB,PARD3,UNC13D,MINK1,MAP3K13,AGO2,ZNF346,CSNK1A1,FOXP1,ANKRD54,IQGAP2,PTPN2,TMEM161A,FBXO31,CD44,HSD17B12,SMARCAD1,ARHGEF12,PIK3CB,NEU1,POLR3A,DKK1,TAF4,TBX3,CSRNP1,BCAS3,FNTB,MYRF,RBPJ,TAF12,NR2F2,ZNF292,CUL4A,PLRG1,PRKCA,RAC3,GABPB2,UBR5,LPIN1,GIPR,EXOC1,S100A10,RNF111,DPH6,MEIS3,SEH1L,TBC1D8,DDN,NR6A1,NOL8,EYA3,CUX1,VSNL1,TCEB3,HSH2D,SEMA3F,SUPT20H,DDX60,SAP30BP,SPOP,SKIL,DDAH2,LSM14A,CCNT1,ARL6IP5,NSMCE1,SEMA3C,NRP1,BMI1,SPOCK2,RFXAP,SYNPO,ZMAT3,EFNB2,WDR75,IFT57,JUP,CDC42EP2,EGR1,ZHX3,ANKRD17,PID1,CRACR2A,PDCD5,TGFBR2,CD226,CHD5,PRKCE,FKBP1A,ENTPD5,MYC,PLEKHA2,CAV2,TERF2,ADARB1,EXOSC2,SYNGAP1,RREB1,RAP1B,ARID1A,NELFA,PLCB1,ARIH2,CAT,KIDINS220,NSF,HIF1A,SPEN,NCOR1,SMYD3,AMOTL1,SYT17,BIRC6,FOSL2,PDE3A,BLOC1S2,TERF2IP,ASNS,SLX4,SHC1,PPID,LPIN2,DTNBP1,KMT2A,CASP8AP2,BRD4,PREX1,DLG4,SATB2,MED16,SETD7,STK10,SERP1,ERC1,SNCA,VDR,MSX2,CAMK2D,SMARCC1,DNAJA3,H2AFX,ANXA2,MID1,FGFBP3,BRAF,TCF3,IKBKAP,GDPD5,RPS6KA5,FOXO3,MAD2L2,NEDD4,SFR1,ABL1,ELP5,TRIAP1,RDX,NLGN3,EXOSC4,S100A14,DYNC2H1,YBX3,LARP4B,MAP3K14,MBTPS2,SLC40A1,PXN,APEX1,WDFY3,FZD3,KCNMA1,TBRG4,PTK2,KLF6,GUF1,POLR2A,COL26A1,STX18,ATM,SVIL,APAF1,DDIT3,STK4,KAT6A,NF1,ATRX,KMT2E,PTPRA,RCHY1,SIRT2,WNT2B,SMARCB1,ANAPC1,RAP1A,ANAPC11,ANAPC10,HYAL1,ZEB1,RELB,PCOLCE2,SLC35C2,CARM1,TRIM14,PRKACB,SRPK2,ZBTB17,TNK2,DEAF1,TRIM13,GPM6A,FBXW4,SKAP2,SIRT6,VWCE,ARRDC3,CAV1,SOX4,KMT2C,ARPC3,TAF9B,UBTF,RHOU,PAF1,GATA6,MKL2,RLTPR,CLU,ZC3H8,NOCT,MTCH1,VIPR1,RELL2,FN1,TAF1,PAX2,CMTM3,RHBDD1,DDIT4,NAMPT,ELL,MCAM,BUD31,SEMA3D,TENM3,NRIP1,XPO5,ELP3,PSMA1,WWC1,LIG4,PRDM1,EIF2A,SYT1,HERPUD1,ISG15,UBE2E1,MYBBP1A,BICD1,FSCN1,RRAGA,PTRH2,ZFP90,PFDN2,TBL1X,FNBP1L,N4BP2L2,TCF12,CHMP2A,DLL4,ASH1L,CEMIP,SMARCA4,PBX1,PIBF1,MIEF1,RRN3,KCTD11,BRE,CAMTA2,NVL,MET,ITGAX,TSPAN14,C6orf89,HTRA2,MAML3,MOSPD1,PRAME,PHLDB2,GRHL3,ATXN1,DKC1,EDEM2,ZC3H12A,IKZF4,ADNP,COPS5,CEBPZ,ARNTL,DUSP19,HEATR1,DISP1,SCARB1,ARC,TMEM101,TSPAN5,DNAJC2,TNIK,SH2D3A,SUPT6H,CAMK1,CLSTN2,ATF7IP,SEMA3E,PPP1R1C,PIP4K2A,BMP6,PRKCH,CTNNBL1,HAS3,SCN1B,SHMT2,UTS2,AMOT,DMRT1,PKNOX1,RPS6KB2,ARNTL2,KDM6B,MSX1,FGF2,ZNF821,KDM5A,MEN1,SYMPK,HSPA1B,RERE,GADD45A,MPP7,VPS37B,NCBP2,NFKBIB,ZAK,HRH1 |
| 1.098e-02 | -4.51 | V$CREB_Q2 | MSigDB lists | V$CREB_Q2 | 256 | 46 | 17758 | 2279 |
PTP4A1,OXNAD1,IFT57,CYLD,BRAF,ID1,EGR1,MAP3K13,PAFAH1B1,ZBTB37,OSBPL9,RCAN1,CHAC1,RING1,JAG1,SREBF2,CACNB2,GLYR1,IKBKB,RELB,JOSD1,ETF1,ALDH18A1,PABPC1,FGF9,SLC38A1,NR6A1,RAB7A,TLE3,TEX14,TPM4,LDHA,MRRF,GNL1,MARCH6,MBNL2,TMEM175,HERPUD1,DDX3X,CAMK2D,RBBP8,GTF2A1,ZZEF1,PER1,VPS37B,ADAM9 |
| 1.099e-02 | -4.51 | AGGGCAG,MIR-18A | MSigDB lists | AGGGCAG,MIR-18A | 134 | 27 | 17758 | 2279 |
PFKFB4,SNX27,ZCCHC14,BCKDK,PXN,ZFYVE1,AGPAT4,SETD2,HOMER2,MAPK8IP3,LRRC8A,ARID1A,KCNH3,ENC1,MBNL2,MAT2A,PHC2,VDR,RNF40,EIF4ENIF1,KDM2A,HIC2,CRCP,RUNX1,IGF2BP1,MAPT,PCSK6 |
| 1.100e-02 | -4.51 | EIF6 (eukaryotic translation initiation factor 6) | protein interactions | 3692 | 139 | 30 | 16036 | 2270 |
BCCIP,SNU13,CUL7,EIF3C,GINS3,ACTG1,GLTSCR2,GNL3,EIF3J,SIRT7,AKT1S1,CEP126,ENOX1,NOP58,ABCF1,BZW2,HSPA1A,PUM3,POP1,RARS,HPRT1,ZNF622,ACAP3,RNF2,FUS,RAN,ITGB4,FBL,YARS,NMD3 |
| 1.105e-02 | -4.51 | mitotic recombination | biological process | GO:0006312 | 40 | 11 | 16441 | 2138 |
RFC4,RFC3,POLE2,PRIM2,APEX1,NSMCE2,POLA1,XRCC2,RAD51B,RAD54B,RPA1 |
| 1.106e-02 | -4.50 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia | 1489 | 220 | 17775 | 2278 |
IMMP2L,ZNF292,MYCBP2,THOC5,UBN1,NF1,ATRX,ZNF107,RNF43,BCOR,SEC16A,ZNF37A,SMARCB1,DST,PDZD2,SRSF2,RAP1A,FAAH2,HKR1,ZNF85,KDM5C,HCFC2,ZNF3,ZNF646,PTPRK,DSC3,CHD9,NRAS,BAZ2A,NR6A1,CDK4,ANK2,NOL8,BRCA1,KMT2C,ZSCAN2,KCNH2,SON,TCTN1,ZNF91,ZNF197,SPOP,PEX1,DDX3X,DYRK1B,GLS,LSS,AHNAK,BRCA2,TRRAP,SUFU,TP53BP1,EEFSEC,ARL6IP5,DPP4,CSMD3,DNAH2,ABCC3,RUNX1,MAGI1,DCAF5,PTPN14,EP400,CDC42EP2,FAM189B,SEC24D,ANKRD17,TRIO,NKD2,OPHN1,NHS,BARX2,EVPL,CDC73,ARID1B,MTUS1,TOX4,TECTA,PRKCE,SIPA1L3,SCAF1,CACNB2,ISPD,SEMA3D,TIMELESS,SLC16A9,AGL,ANGPT2,SCAF11,GTF2H3,TRAPPC9,COL17A1,IFNGR2,KIAA1143,RREB1,IFT43,EPS15L1,SETD2,RYR2,PTPN12,PRDM1,IMPDH2,ARID1A,SRA1,ZNF425,DAGLA,SYCP2L,ATXN7,LRP1B,ATAD5,FAM135A,SPAG9,TTC38,KIAA0355,VCAN,SPEN,FAT1,DNAH17,ZNF160,ARHGAP12,BPNT1,WDR33,PDSS2,MAP2K4,DMXL2,TCF12,RTTN,CYLD,TRPM2,ABCA3,SUCLG1,PCNT,ARID2,LPCAT2,URB2,NTSR1,SMARCA4,TMEM104,DENND3,HNRNPA3,PLXNB1,ZNF608,SOCS1,GSTA4,ADCK4,MET,TMEM200A,KDM3B,PHLDB2,KMT2D,STAMBP,SLCO6A1,LRRC8A,R3HDM1,ATP8B2,NUP214,ERC1,UBR4,FGFR1,BTBD11,SLC39A14,ADNP,ATG7,ZNF436,IFT140,SLC25A11,PDCD11,DMGDH,NOSTRIN,BRAF,SULT1C2,CLSTN2,JMJD6,ATG2B,CCDC7,MLH1,BHLHE40,RNASEH2B,RBM19,IKBKAP,RMI1,PIP4K2A,NEDD4,IQGAP2,ABL1,ZNF239,SACS,NEBL,STC2,PRICKLE2,UPF2,PCK2,AMOT,DIS3L2,NAV3,FAM120B,KDM6B,TSHZ1,TMC7,DDHD1,PPP1R21,PSMC3IP,MARS,R3HDM2,MEN1,ZNF467,GUF1,CASC1,TMEM175,UBC,CDH24,DSC2,EIF2S1,ATM,RWDD2B,TAF12,ITGB4,SORCS2,RPS6KC1,DOCK6 |
| 1.106e-02 | -4.50 | hairy_cell_leukaemia | COSMIC cancer mutations | hairy_cell_leukaemia | 1489 | 220 | 17775 | 2278 |
ZNF292,IMMP2L,MYCBP2,THOC5,UBN1,NF1,ATRX,ZNF107,RNF43,BCOR,SEC16A,ZNF37A,SMARCB1,DST,PDZD2,SRSF2,RAP1A,FAAH2,HKR1,ZNF85,KDM5C,HCFC2,ZNF3,ZNF646,PTPRK,DSC3,CHD9,NRAS,BAZ2A,NR6A1,CDK4,ANK2,NOL8,BRCA1,KMT2C,KCNH2,ZSCAN2,SON,TCTN1,ZNF91,ZNF197,PEX1,SPOP,DYRK1B,GLS,DDX3X,LSS,AHNAK,BRCA2,TRRAP,SUFU,TP53BP1,EEFSEC,ARL6IP5,CSMD3,DPP4,ABCC3,DNAH2,RUNX1,MAGI1,DCAF5,PTPN14,EP400,CDC42EP2,SEC24D,ANKRD17,FAM189B,TRIO,NKD2,NHS,OPHN1,BARX2,EVPL,CDC73,ARID1B,MTUS1,TOX4,TECTA,PRKCE,SIPA1L3,SCAF1,CACNB2,ISPD,SEMA3D,TIMELESS,SLC16A9,AGL,ANGPT2,SCAF11,GTF2H3,TRAPPC9,COL17A1,IFNGR2,KIAA1143,RREB1,IFT43,SETD2,EPS15L1,RYR2,PTPN12,IMPDH2,PRDM1,ARID1A,SRA1,DAGLA,ZNF425,SYCP2L,ATXN7,LRP1B,FAM135A,SPAG9,ATAD5,KIAA0355,TTC38,VCAN,SPEN,FAT1,DNAH17,ZNF160,ARHGAP12,BPNT1,WDR33,PDSS2,MAP2K4,RTTN,DMXL2,TCF12,ABCA3,CYLD,TRPM2,SUCLG1,PCNT,ARID2,URB2,LPCAT2,NTSR1,SMARCA4,TMEM104,DENND3,HNRNPA3,PLXNB1,ZNF608,SOCS1,GSTA4,ADCK4,MET,TMEM200A,KDM3B,PHLDB2,KMT2D,STAMBP,SLCO6A1,R3HDM1,LRRC8A,ATP8B2,NUP214,ERC1,UBR4,FGFR1,BTBD11,SLC39A14,ADNP,ATG7,ZNF436,IFT140,SLC25A11,PDCD11,DMGDH,NOSTRIN,BRAF,SULT1C2,CLSTN2,JMJD6,ATG2B,CCDC7,MLH1,RNASEH2B,RBM19,IKBKAP,BHLHE40,RMI1,PIP4K2A,NEDD4,IQGAP2,ABL1,ZNF239,SACS,NEBL,STC2,PRICKLE2,UPF2,PCK2,AMOT,NAV3,DIS3L2,FAM120B,KDM6B,DDHD1,TMC7,TSHZ1,PSMC3IP,PPP1R21,MARS,R3HDM2,ZNF467,MEN1,GUF1,TMEM175,CASC1,UBC,CDH24,DSC2,EIF2S1,ATM,TAF12,RWDD2B,SORCS2,ITGB4,RPS6KC1,DOCK6 |
| 1.108e-02 | -4.50 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | 191 | 36 | 17758 | 2279 |
SEPHS2,COMMD10,WDR75,SARS,FAM189B,DYM,CAMK1,TUBE1,LPCAT3,CCDC47,POP5,FRRS1,RNF141,FKBP1A,NT5C,PRADC1,C15orf41,MCEE,NARS2,ANTXR2,RFC4,GINS3,APEX1,CCNDBP1,EVI5,POLG2,POLR3G,PLIN2,ETFDH,COQ9,WDR7,ABCC3,PUS1,TSEN2,TSPAN5,AP2S1 |
| 1.108e-02 | -4.50 | GSE17721_POLYIC_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDM_DN | 191 | 36 | 17758 | 2279 |
SRM,ID1,FN1,DDX18,PSTPIP2,SPRYD7,JMJD6,SLC6A8,PDCD5,LYRM2,DENR,FARSA,RRN3,POLR3D,DNAJB6,IKBKB,POLE3,ANP32B,PRMT3,FDFT1,PEA15,LAMA4,SLC40A1,AP4S1,CDK4,GNL3,PSMG1,RAP1GDS1,RAB10,HSD3B7,FDPS,NCBP2,ZC3H8,DDX10,FAM118A,GPATCH4 |
| 1.108e-02 | -4.50 | GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN | MSigDB lists | GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN | 191 | 36 | 17758 | 2279 |
SEPHS2,TRIM16,SEC24D,TRPM6,TRAK1,TBCCD1,ZFP36L1,SPATS2L,SEMA6A,SLC39A1,RGS17,SYN2,SLC39A7,ZNF142,SHMT2,ZNRD1,PPM1K,TLCD1,TSTA3,ZNF414,TMEM126A,TOP3A,WDHD1,ZNF324B,PRDM1,TRAPPC6B,RBM28,SLC9A5,SAP30BP,S100A16,WARS,ZNF557,TIMM17A,TBX3,RNF214,TMEM158 |
| 1.108e-02 | -4.50 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | 191 | 36 | 17758 | 2279 |
COMMD10,MPI,NCOR2,TTN,SPRED2,BCKDK,EGR1,TFIP11,SIRT7,LAGE3,FAM13A,PRKCA,DOPEY1,MAD1L1,FHIT,MAP3K14,CLK2,TBC1D8,GON4L,UPP1,EYA3,HIST1H4J,HLA-DMA,PAF1,SEC31A,TPD52L2,ZNF266,LMBR1L,KIAA0355,ABHD3,SYNGR2,SURF1,INTS9,TRAF3,VASH2,RNF114 |
| 1.108e-02 | -4.50 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | 191 | 36 | 17758 | 2279 |
TRIP6,PPARGC1B,ZNF280C,CMTM3,UBR5,MBNL1,PIP4K2A,LPIN1,MAN1A1,NAMPT,CD96,SACS,LPIN2,SYNJ2,PCK2,NRIP1,CNOT4,PRKACB,EIF4E3,IL11RA,GPHN,RB1CC1,WLS,ZMYM5,CUX1,FAM126B,DDX60,RAB10,MAT2A,OSBPL1A,HLA-DMA,RBBP8,SYNCRIP,PURB,ANXA2,TESC |
| 1.109e-02 | -4.50 | GLO1 (glyoxalase I) | protein interactions | 2739 | 37 | 11 | 16036 | 2270 |
CUL7,PSMG4,PRDX6,MAP3K13,ITPA,ATIC,UMPS,AGL,IGBP1,PPA1,HSD17B14 |
| 1.109e-02 | -4.50 | GSPT1 (G1 to S phase transition 1) | protein interactions | 2935 | 37 | 11 | 16036 | 2270 |
MCM5,ATG7,ATXN1,RDX,ETF1,UBR5,PABPC1,BIRC2,SMG1,PABPC4,SPTAN1 |
| 1.109e-02 | -4.50 | MYL12A (myosin light chain 12A) | protein interactions | 10627 | 37 | 11 | 16036 | 2270 |
GLS,SYNCRIP,SUV39H2,TP53BP1,HERC1,SVIL,LIG4,MYH9,BRCA1,IGBP1,CDC73 |
| 1.111e-02 | -4.50 | MACROMOLECULAR_COMPLEX_ASSEMBLY | MSigDB lists | MACROMOLECULAR_COMPLEX_ASSEMBLY | 276 | 49 | 17758 | 2279 |
EIF3C,CDC42EP2,PRPF31,SF3A3,PBX1,ATF7IP,RSF1,IKBKAP,COX10,NDUFS7,PAIP2,PTRF,ATXN2,MED24,CELF1,CCDC88C,VCL,SNAPC5,SF3A1,SRPK2,SCAF11,PXN,LAMC1,SKAP2,SFSWAP,MTIF2,EIF3J,EIF4A2,MED27,BCS1L,DLG4,MED16,EIF2A,SYT1,EIF3H,CHAF1A,GEMIN5,SMAD3,TAF2,EPRS,HPRT1,KPNA3,CDK9,SET,SURF1,PEX13,NDUFS5,EIF2B3,PARD3 |
| 1.111e-02 | -4.50 | TGATTTRY_V$GFI1_01 | MSigDB lists | TGATTTRY_V$GFI1_01 | 276 | 49 | 17758 | 2279 |
TCF12,SARS,GNB3,FN1,TRERF1,ATRX,PAX2,C1QTNF7,LAMTOR3,MAB21L3,CLSTN2,PPP2R2A,IP6K2,CD226,POGZ,IGF2BP3,PHC2,CHN1,ATP5G2,PVRL3,JAZF1,RNF111,JOSD1,GEMIN4,CALN1,SRPK2,BDNF,GPM6A,CRIM1,TEAD1,FOXN3,AGPAT4,WDPCP,JMJD1C,POU2F1,RANGAP1,SNAP25,SOX4,SNCA,ALKBH3,KPNA3,HERC1,HOXA3,TMEM117,SEMA3C,ANXA2,MID1,RAB30,MEF2C |
| 1.114e-02 | -4.50 | EIF3F (eukaryotic translation initiation factor 3, subunit F) | protein interactions | 8665 | 78 | 19 | 16036 | 2270 |
EIF3C,FN1,ATP6V1A,EIF3J,EIF4A2,ATXN1,CSNK2A1,C11orf49,DKC1,UBC,EIF3H,DDX3X,ASCC3,COPS5,JOSD1,RNF2,RPS6KB1,MSH4,SRRM2 |
| 1.114e-02 | -4.50 | FLNB (filamin B, beta) | protein interactions | 2317 | 78 | 19 | 16036 | 2270 |
FLNC,DCTN3,CUL7,FN1,SIRT6,SIRT7,ATF7IP,MLH1,AP1B1,UBR4,FLNB,ISG15,AHNAK,FMNL1,MAD1L1,RNF2,MAP2K4,NMD3,HNRNPM |
| 1.114e-02 | -4.50 | EIF3I (eukaryotic translation initiation factor 3, subunit I) | protein interactions | 8668 | 78 | 19 | 16036 | 2270 |
HERC2,SLC3A2,DNAJA4,EIF3C,EIF3J,SIRT7,SETD2,NDUFB5,LIG4,TGFBR2,UBR5,EIF3H,DDX3X,SUB1,MYC,RNF2,RAN,POLR1C,SRRM2 |
| 1.116e-02 | -4.50 | cofactor biosynthetic process | biological process | GO:0051188 | 151 | 30 | 16441 | 2138 |
ACSL5,GPHN,ELOVL6,CPOX,UROD,MTHFD1L,LIAS,COX10,MAT2A,TPK1,NAMPT,FLAD1,GART,MTHFD2,ALAD,COQ9,ATIC,BDH2,ACOT11,PPCDC,ME1,HMBS,FXN,COQ3,MTHFD2L,TMEM14C,PDSS2,HSD17B12,SLC25A1,MTHFD1 |
| 1.117e-02 | -4.49 | superpathway of cholesterol biosynthesis | BIOCYC pathways | META_PWY66-5 | 23 | 8 | 907 | 131 |
LSS,IDI1,MVK,FDPS,SQLE,DHCR7,HMGCR,FDFT1 |
| 1.117e-02 | -4.49 | intracellular transport | biological process | GO:0046907 | 1375 | 207 | 16441 | 2138 |
IMMP2L,THOC5,BCAS4,PRKAB2,KIF5A,DDX19A,ENAH,NBEAL1,NUP160,SEC16A,TOM1L1,SRPRB,EXOC1,RPS16,SRSF2,PMAIP1,NSRP1,ATP5G2,CNIH3,ATG3,NCKIPSD,AP1M1,VPS52,RAN,TIMM50,CDC37,GDAP1,WLS,ANK2,ATOX1,AP4B1,COL4A3BP,CUX1,NOL6,AKAP12,ZDHHC14,FLVCR1,LSG1,MPC1,STOML2,KIF16B,PEX1,TIMM44,RBSN,TOM1L2,CTAGE5,VPS13D,SGSM2,FIS1,C2CD5,NMD3,CHMP4C,HERC2,IFT57,STX8,SEC24D,VTA1,STXBP6,NKD2,PIK3R4,SMG7,XPO7,SSR4,CLINT1,TIMM10,RHBDD1,SPIRE1,PRKCE,MLX,VAPB,TNPO3,TOMM34,USE1,TIMM8B,RANBP6,TRAPPC9,MYO10,IFT43,XPO5,RYR2,TRAPPC6B,EVI5,CPT1A,BLOC1S4,HERPUD1,TCF7L2,ATP9B,SEC31A,VPS13C,MYBBP1A,SPAG9,KPNA1,BICD1,KIDINS220,NME7,RPL28,NSF,HIF1A,SNAP23,SRP68,HK2,SIL1,PEX13,NAPA,SRP14,TESC,SGSM3,COG5,SNX27,CHMP2A,RAB11FIP4,PAFAH1B1,RPS29,MYO7A,VTI1A,AP1B1,DENND3,STAM,EEA1,GBF1,RPAIN,BLOC1S2,VPS18,ACD,NUP133,ZDHHC6,DTNBP1,NBEA,BCAP29,CORO1A,CPSF3,AHCYL1,ZC3H3,IPO11,LYST,AUP1,SEC24A,TUBA1A,RAB7A,ATXN1,AKAP13,NUP214,ERC1,VPS53,RAB10,ATP5D,RANBP2,ARHGAP21,IFT81,KPNA3,TIMM17A,IFT140,NFASC,ANXA2,AP2S1,SMG1,RAB30,PARD3,MAPT,HM13,SCAMP3,CAMK1,TRAK1,VPS45,SLC25A12,MAP1S,KIF5C,GAS6,MON2,OPA1,TGFB2,NOL3,RSRC1,TMCO6,ANKRD54,NEDD4,SLC25A20,PEX7,SEC24C,PMPCA,SDCBP2,UPF2,DYNC2H1,FGF9,VPS37A,AP4S1,FGF2,WDFY3,PACS1,PDE2A,RHOT2,NOP58,UBC,RERE,MFN2,CACNB1,ZDHHC11,WDR35,STX1A,STX18,VPS37B,SET,NCBP2,XPO6,KIF1B,DDIT3,IPO4 |
| 1.118e-02 | -4.49 | TAF15 (TATA box binding protein associated factor 15) | protein interactions | 8148 | 57 | 15 | 16036 | 2270 |
CUL7,CUL4A,TAF1,COPS5,SIRT7,CUL2,RNF2,FUS,TAF12,COPS6,BMI1,SAP30BP,POLR2A,RPA1,RPS6KB2 |
| 1.118e-02 | -4.49 | BABAM1 (BRISC and BRCA1 A complex member 1) | protein interactions | 29086 | 57 | 15 | 16036 | 2270 |
TERF2IP,USP7,NDUFA5,BRE,NSF,SFXN4,PYCRL,UBXN1,SHMT2,SLC25A11,RANGAP1,BRCA1,FAM210A,BRCC3,UBC |
| 1.118e-02 | -4.49 | MRPL11 (mitochondrial ribosomal protein L11) | protein interactions | 65003 | 57 | 15 | 16036 | 2270 |
DDX28,CAMK2D,HMBOX1,TFCP2,COPS5,MRPL10,MPV17,VPS52,TMEM177,RNF2,SLC16A9,SSBP1,PNMA1,POLR3A,MRPS30 |
| 1.120e-02 | -4.49 | NEGATIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_RNA_METABOLIC_PROCESS | 128 | 26 | 17758 | 2279 |
ZNF254,KDM5B,ZHX3,NR6A1,FOXN3,ARID5B,CUX1,NFX1,HDAC8,ATF7IP,PRDM1,BCOR,RSF1,MEN1,SUPT5H,SMAD3,NSD1,SUPT4H1,VPS72,KLF4,JAZF1,TBX3,ZEB1,ZNF148,RBPJ,NRIP1 |
| 1.121e-02 | -4.49 | Canonical NF-kappaB pathway | Pathway Interaction DB | nfkappabcanonicalpathway | 23 | 8 | 2227 | 319 |
CYLD,IKBKB,TNFRSF1A,ATM,RAN,PRKCA,BIRC2,ERC1 |
| 1.125e-02 | -4.49 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | 74 | 17 | 17758 | 2279 |
PTP4A1,CLDN15,EGR1,CDC42EP2,GPCPD1,ARRDC3,AKAP12,FAM126B,FOSL2,KLF6,SPIRE1,SLC7A11,MYC,PVRL3,SLC4A7,CLDND1,SMG1 |
| 1.125e-02 | -4.49 | RIZ_ERYTHROID_DIFFERENTIATION | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION | 74 | 17 | 17758 | 2279 |
ZBTB17,ID1,RAB7A,POLA1,CENPB,POU2F1,BRCA1,MCM2,FOSL2,POLG2,EXO1,POLE2,MCM5,ARNTL,BMI1,MID1,TERF2 |
| 1.126e-02 | -4.49 | positive regulation of cardiac muscle tissue development | biological process | GO:0055025 | 25 | 8 | 16441 | 2138 |
EFNB2,FGF9,GATA6,FGF2,BMP4,RBPJ,FGFR1,MEF2C |
| 1.126e-02 | -4.49 | nucleotide-excision repair, DNA damage recognition | biological process | GO:0000715 | 25 | 8 | 16441 | 2138 |
CUL4A,COPS4,XPC,COPS3,COPS5,COPS7B,COPS6,UBC |
| 1.126e-02 | -4.49 | mesodermal cell differentiation | biological process | GO:0048333 | 25 | 8 | 16441 | 2138 |
KDM6B,HMGA2,KLF4,PAX2,ITGA2,TRIM15,BMP4,ITGB4 |
| 1.129e-02 | -4.48 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | MSigDB lists | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | 16 | 6 | 17758 | 2279 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 1.129e-02 | -4.48 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | MSigDB lists | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | 16 | 6 | 17758 | 2279 |
ATM,BRCA1,BRCA2,TP53BP1,RPA1,H2AFX |
| 1.129e-02 | -4.48 | FARMER_BREAST_CANCER_CLUSTER_6 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_6 | 16 | 6 | 17758 | 2279 |
RPS6KB1,RNF43,SUPT4H1,POLG2,TRIM37,FTSJ3 |
| 1.129e-02 | -4.48 | KYNG_NORMAL_AGING_UP | MSigDB lists | KYNG_NORMAL_AGING_UP | 16 | 6 | 17758 | 2279 |
PMEPA1,MBNL2,NSMCE1,C15orf41,ITGA2,FRA10AC1 |
| 1.129e-02 | -4.48 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | MSigDB lists | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | 16 | 6 | 17758 | 2279 |
GLS,ASNS,ALDH18A1,PSAT1,PHGDH,PYCR1 |
| 1.135e-02 | -4.48 | actin binding | molecular function | GO:0003779 | 389 | 67 | 16491 | 2164 |
CGN,PSTPIP2,ACTR3,MYO7A,MYH9,TBCCD1,COBLL1,ENAH,CORO6,PPP1R9A,FLNB,DST,VPS18,ABL2,FMNL1,SNTG2,MYH3,IPP,MYH15,CORO1A,PXK,VCL,FLNC,DBN1,FMNL3,EVL,SSFA2,LIMA1,GMFB,MARCKSL1,COTL1,ENC1,TMSB4X,ARPC3,MISP,MKL2,TPM1,SYNPO,TNNC1,TTN,SSH2,OPHN1,MAP1S,SPIRE1,IQGAP2,PRKCE,ABL1,NEBL,TMSB10,RDX,ACTR3B,FMNL2,MICAL3,SPTAN1,PPP1R9B,MYO10,KCNMA1,HOMER2,TPM4,PHACTR2,PTK2,PALLD,INF2,FSCN1,SVIL,PDLIM5,CORO2B |
| 1.138e-02 | -4.48 | GCM_SUPT4H1 | MSigDB lists | GCM_SUPT4H1 | 57 | 14 | 17758 | 2279 |
HMGA2,NRF1,MVK,SLC30A3,SUPT4H1,TAF1,DDX18,TIMM17A,VPS72,DPF2,SLC16A1,TRIP13,LYST,RING1 |
| 1.138e-02 | -4.48 | GTGTCAA,MIR-514 | MSigDB lists | GTGTCAA,MIR-514 | 57 | 14 | 17758 | 2279 |
TCF12,EIF4ENIF1,PCCA,ARRDC3,PRICKLE2,SVIL,ENAH,PPIL1,PTPRG,IGBP1,AGAP1,DHX57,CARM1,NAV3 |
| 1.139e-02 | -4.47 | RPAP2 (RNA polymerase II associated protein 2) | protein interactions | 79871 | 52 | 14 | 16036 | 2270 |
RFC4,INTS7,PRPF31,EIF4A2,POLR3E,MED24,GPN1,GTF3C3,BRCA1,POLR3B,EHBP1,POLR3A,NEDD4,POLR2A |
| 1.139e-02 | -4.47 | POLD1 (polymerase (DNA directed), delta 1, catalytic subunit) | protein interactions | 5424 | 52 | 14 | 16036 | 2270 |
TERF2IP,POLK,COPS5,MYC,CDK4,PURB,RNF2,UPF2,CEP126,COPS6,TSEN2,TERF2,RPA1,TBC1D2 |
| 1.139e-02 | -4.47 | CHROMOSOME_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | CHROMOSOME_ORGANIZATION_AND_BIOGENESIS | 122 | 25 | 17758 | 2279 |
KAT8,HMGA2,EHMT1,HDAC8,SIRT2,RSF1,ARID1A,DKC1,RPS6KA5,CHAF1A,TERF2IP,NSD1,SUPT4H1,ACD,SMARCC1,SUV39H2,SET,MSH3,PDS5B,PAM,HIRIP3,MAP3K12,CARM1,TERF2,KAT6A |
| 1.140e-02 | -4.47 | NAT10 (N-acetyltransferase 10 (GCN5-related)) | protein interactions | 55226 | 42 | 12 | 16036 | 2270 |
TSR1,CUL7,FN1,DHX37,DDX18,SIRT7,ABCF2,RNF2,BRCA1,BMI1,NOP58,TOP1 |
| 1.140e-02 | -4.47 | TRIP4 (thyroid hormone receptor interactor 4) | protein interactions | 9325 | 42 | 12 | 16036 | 2270 |
ASCC3,ASCC1,GTF2A1,NEK6,ALKBH3,PPARG,MED27,MED15,MED24,FUS,NR2F2,POLR2A |
| 1.140e-02 | -4.47 | VPS4B (vacuolar protein sorting 4 homolog B (S. cerevisiae)) | protein interactions | 9525 | 42 | 12 | 16036 | 2270 |
CHMP2A,NSF,ITPA,VTA1,UBXN1,VPS45,PRKCA,AHCYL1,IGBP1,NUP214,BIRC2,HTRA2 |
| 1.140e-02 | -4.47 | PSIP1 (PC4 and SFRS1 interacting protein 1) | protein interactions | 11168 | 42 | 12 | 16036 | 2270 |
HMGA2,SUB1,CUL7,BANF1,ZC3H18,CSNK2A1,EXOSC4,MEN1,KMT2A,SON,FTSJ3,RPA1 |
| 1.140e-02 | -4.47 | SULT1A1 (sulfotransferase family 1A member 1) | protein interactions | 6817 | 42 | 12 | 16036 | 2270 |
TTC1,SULT1C2,TOM1L2,TRIP6,THADA,UBXN1,TPM4,ZRANB2,TUBB6,TPM1,AHCYL1,STAM |
| 1.140e-02 | -4.47 | EXOC1 (exocyst complex component 1) | protein interactions | 55763 | 42 | 12 | 16036 | 2270 |
DST,KANSL1,RB1CC1,CEP295,KIF5A,TRIO,EXOC4,KIAA1551,DTNBP1,KDM1A,SPTAN1,SFR1 |
| 1.140e-02 | -4.47 | CORO1A (coronin, actin binding protein, 1A) | protein interactions | 11151 | 42 | 12 | 16036 | 2270 |
SMAD3,SNU13,IFT57,FMNL1,RABGAP1L,ACTR3,VARS,CORO6,POLR1C,GIT2,TJAP1,DKK1 |
| 1.140e-02 | -4.47 | DST (dystonin) | protein interactions | 667 | 42 | 12 | 16036 | 2270 |
EXOC1,TNIK,COL17A1,CELSR3,PRKAB2,SIRT7,DTNBP1,CEP63,ITGB4,PRMT5,KIAA1549,TERF2 |
| 1.144e-02 | -4.47 | PABPC4 (poly(A) binding protein, cytoplasmic 4 (inducible form)) | protein interactions | 8761 | 128 | 28 | 16036 | 2270 |
MSI2,SART1,SNU13,CUL7,CUL4A,FN1,SKIV2L2,TRA2A,PLRG1,SIRT7,GNL1,APRT,PHGDH,UBC,ECH1,RPA1,SURF2,ATXN2,COPS5,CUL2,RNF2,FBL,BMI1,IGBP1,ZC3H3,PPA1,TERF2,SRPK2 |
| 1.146e-02 | -4.47 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 185 | 35 | 17758 | 2279 |
ZNF516,FEZ2,FOXO1,TRIM16,DDR2,SSR4,CHD5,SRPRB,SACS,RAN,ARNTL2,FAM127A,NARS,EIF3J,PCCA,ELOVL6,ARID5B,FZD3,ATXN1,CAMSAP2,SLC35F2,SERP1,UBE2E1,ZC3H12A,DYNC1H1,SMAD3,YIF1A,IFT81,LARGE,BBIP1,DNAJC12,TRAF3,MAGI1,IFITM2,CEP170 |
| 1.146e-02 | -4.47 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_DN | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_DN | 185 | 35 | 17758 | 2279 |
GGT1,OXNAD1,CCDC53,C16orf52,ALG8,CHAC1,TIMM10,GBF1,FLNB,MAN1A1,PRKCH,ZNF827,SIPA1L3,UBE3A,SHMT2,FHIT,HSD17B14,DDN,NAA38,TUBA1A,SIRT6,CLYBL,EIF2A,GSTCD,PLCXD2,CCDC28B,GEMIN5,AHNAK,DAGLB,ZZEF1,SURF1,FNTB,SEMA3C,TBXA2R,PRKAR2A |
| 1.146e-02 | -4.47 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_UP | 185 | 35 | 17758 | 2279 |
PTCD2,UTP14A,TUBB6,HLTF,CIAPIN1,CEP164,CAD,GATC,SUV39H2,YLPM1,NVL,GPATCH1,CTR9,POLR3B,SAMD13,PRADC1,PRMT5,PRPS1,PKNOX1,FAM98A,DDX28,FAM172A,PPAT,CDK4,BCS1L,FLVCR1,POLG2,NAPEPLD,USP46,HLCS,COQ9,ORC5,TSSC1,UMPS,WDR66 |
| 1.146e-02 | -4.47 | GSE27786_LSK_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_LSK_VS_CD4_TCELL_DN | 185 | 35 | 17758 | 2279 |
ZNF292,CHMP2A,DNAJA4,ACTG1,CERS5,WDR26,GRINA,SIRT2,HLTF,MFHAS1,CHD7,TTLL11,RAP1A,MLX,JAZF1,PPCDC,ANKRD11,GLTP,PLEKHA2,FMNL3,TNK2,C19orf43,PREX1,RAP1GDS1,GNL1,DNTTIP1,KIDINS220,AGTPBP1,GLG1,TBPL1,CTAGE5,VPS13D,DPP4,BRD9,TNRC6A |
| 1.146e-02 | -4.47 | GSE3982_MAC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_UP | 185 | 35 | 17758 | 2279 |
PCNT,LUZP1,ITFG1,PRPF39,STAM,ETFB,LPIN1,JAG1,NOP16,RAN,ALDH18A1,AHCYL1,ZNF629,TIMM8B,FGF9,ZCCHC14,PCMT1,MINA,R3HDM1,ADSL,PTK2,SOX4,ABCF1,FKBP3,STOML2,IRS1,RARS,FBXO21,NME7,FAM114A2,INTS5,CUL2,PRPF4,ABCC3,CEP170 |
| 1.146e-02 | -4.47 | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDM_DN | 185 | 35 | 17758 | 2279 |
HERC2,BCCIP,TNFRSF21,SLK,WDR13,CENPB,CCDC47,IKBKAP,TTI1,NOP56,FKBP1A,ABL1,DDX56,MPHOSPH10,INTS7,IGF2BP1,PRMT5,LYRM5,LONP1,CARM1,STAG1,DDX24,TBRG4,IMPDH2,HERPUD1,MGAT2,SEC31A,KPNA1,SMARCC1,SYNCRIP,TP53BP1,ZNF330,SOCS4,PPP3CC,FAM118A |
| 1.147e-02 | -4.47 | RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription | REACTOME pathways | R-HSA-504046 | 145 | 30 | 8202 | 1117 |
GATAD2B,GTF2H3,GTF2H2C,POLR1A,NFIA,POU2F1,HIST1H4J,HIST1H2BL,SNAPC4,POLR3A,POLR3G,UBTF,POLR3D,RRN3,PTRF,EHMT2,CHD3,MBD2,POLR3E,H2AFX,CRCP,GTF2H1,HIST2H3D,GTF3C3,POLR3B,POLR1B,POLR1C,ZNRD1,POLR1E,SNAPC5 |
| 1.148e-02 | -4.47 | LUC7L3 (LUC7-like 3 pre-mRNA splicing factor) | protein interactions | 51747 | 47 | 13 | 16036 | 2270 |
SART1,CUL7,CLK1,LUC7L3,COPS5,BANF1,CUL2,NFIA,SHMT2,RNF2,ZRANB2,BMI1,SRPK2 |
| 1.154e-02 | -4.46 | deoxyribonuclease activity | molecular function | GO:0004536 | 67 | 16 | 16491 | 2164 |
HMGA2,APEX1,TATDN3,FAN1,MAP1S,APTX,ZRANB3,EXO1,SLX4,RBBP8,APLF,XRCC2,RAD51B,ALKBH1,TATDN1,OGG1 |
| 1.157e-02 | -4.46 | CDKN2A (cyclin-dependent kinase inhibitor 2A) | protein interactions | 1029 | 151 | 32 | 16036 | 2270 |
NCOR2,MCM6,MCM10,EGR1,FN1,ACTG1,LAMTOR3,ARFIP2,SMARCA4,PRKCA,MCM5,MYC,IKBKB,RNF2,CDK6,TOP1,CLK2,DEAF1,PPP1R9B,TUBA1A,CDK4,GNL3,BRCA1,MCM2,MTR,DYRK1B,AHNAK,HIF1A,COPS5,CUL2,SENP3,NCOR1 |
| 1.161e-02 | -4.46 | MYC_UP.V1_UP | MSigDB lists | MYC_UP.V1_UP | 166 | 32 | 17758 | 2279 |
UTP14A,C10orf2,CHCHD10,NLE1,DCTPP1,PUS3,MPHOSPH10,CCDC124,PCOLCE2,B3GNTL1,POLR1E,PRMT3,METTL1,USE1,ABCC4,MON1A,SCFD2,NOL6,UTP15,TTYH2,PES1,TMEM132B,GEMIN5,HSPBAP1,ERVMER34-1,CAMKMT,PUS1,DDX10,SLC25A26,MMP16,IPO4,NR2C2AP |
| 1.163e-02 | -4.45 | BROMODOMAIN | prints domains | PR00503 | 33 | 8 | 4759 | 462 |
BAZ1A,BRD4,BAZ2B,TAF1,BAZ2A,SMARCA4,BRWD3,BRD9 |
| 1.163e-02 | -4.45 | pigment metabolic process | biological process | GO:0042440 | 62 | 15 | 16441 | 2138 |
HPRT1,GART,ALAD,PPAT,CPOX,UROD,BDH2,GPR143,APRT,HMBS,HMOX2,FXN,COX10,TMEM14C,PRPS1 |
| 1.168e-02 | -4.45 | TRAP1 (TNF receptor-associated protein 1) | protein interactions | 10131 | 73 | 18 | 16036 | 2270 |
USP7,CUL7,AK2,FN1,CDK4,HSPA5,PCMT1,WDHD1,TGFBR2,UBC,ASNS,HSDL2,CDK9,TNFRSF1A,H2AFX,FKBP5,COQ3,PRKACB |
| 1.168e-02 | -4.45 | TALDO1 (transaldolase 1) | protein interactions | 6888 | 73 | 18 | 16036 | 2270 |
XYLB,PSAT1,LGALS1,LDHA,ATG2B,PITPNB,ZNF655,DENR,PGD,TERF2IP,RNF40,NME1-NME2,PSMG4,CFDP1,FDPS,ACP1,PRKACB,TERF2 |
| 1.168e-02 | -4.45 | LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) | protein interactions | 4055 | 73 | 18 | 16036 | 2270 |
TNIK,RBCK1,MAP7D1,CCDC113,SPATS2,SPATS2L,TRIM37,BIRC2,MGA,POM121,FGFR1,SKI,IFT81,CCDC112,VAPB,TRAF3,CCDC121,ZC3H3 |
| 1.174e-02 | -4.44 | thyroid | COSMIC cancer mutations | thyroid | 10345 | 1376 | 17775 | 2278 |
ARHGAP26,GGT1,CDCP1,DPH1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,CIAPIN1,SKI,PDZD2,ZFHX3,ATP5G2,THAP4,LETM2,SRRM2,FTSJ3,PPM1K,CCDC57,NRAS,RNMT,KLHL23,LIMA1,UPP1,NFIA,KIF15,C5AR1,WDHD1,ABCC2,SLC9A5,ZNF197,PYCR1,AHNAK,RAD18,SYNGR2,MPV17,RIOK1,TPM1,ZNF532,SLC25A26,P2RY11,BANP,TMEM63C,TRIO,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,MED24,GEMIN4,MRPL21,CCDC88C,PABPC1,PPA1,ANGPT2,NOM1,GATAD2B,IFRD1,STAG1,ZNF587,ARID5B,TYW1,USP10,MAP7D1,ARRDC4,SRA1,USP46,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,RPL28,EHMT2,TRAP1,PDLIM5,SRP14,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,C16orf95,PAFAH1B1,MAB21L3,VTI1A,CD99L2,GRINA,NUP43,ST3GAL6,CBWD5,MCM9,ACD,SETD5,WAC,CLCN6,MMP14,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,EIF3J,SLCO6A1,PCNXL2,CCNDBP1,MEF2D,KCNH3,NUDT15,DSP,VPS53,SLC39A14,ZFAND3,FBXL5,KDM4B,ASTN2,NSMCE2,METTL6,CAMKMT,HOXA3,RPS6KB1,CEP170,METTL2B,CATSPERG,BAG1,MAPT,MORC2,SHQ1,XRRA1,ATG2B,IP6K2,PSMF1,TTLL11,POLR3D,PSMG4,TAF3,NOP16,UNC13A,LTN1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,SAMD4A,RPL22L1,PNMA1,SPTAN1,TTPAL,DDX24,ZC3H18,LDHA,NXN,PPIP5K2,UBC,CCDC150,ANXA1,NSD1,SRCAP,HERC1,ACOX1,ERVMER34-1,AEN,SORCS2,MTMR1,CYP24A1,CUL7,RBM33,WDR13,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,SRSF2,NCKIPSD,ANKRD11,HKR1,ZNF3,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,CDK4,ANK2,HSPA5,PSMG1,LAMA2,KCNH2,BSN,DYRK1B,TCF7L1,LSS,CHD3,AHNAK2,DPP4,PRPF4,MAGI1,BEND6,USP15,CTU2,CLK1,PRSS3,SMAD7,MAPK8IP3,FAN1,ZIC2,ARID1B,RNFT2,MLX,ZNF358,CEP290,CTR9,PNPLA3,LRSAM1,CWF19L2,NIPSNAP1,IFT43,USP49,SETD2,HAUS6,OBSCN,METTL22,ACOXL,TCF7L2,TBC1D2,GRIK4,TTC38,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,OLFM2,UPK3B,ARID2,OSBPL9,NTSR1,RPS29,SLC2A1,DENND3,TNKS1BP1,RADIL,SEMA6A,DDX60L,URB1,PLXNB1,ZNF608,IDI1,NUP133,GRIN2C,ANKRD24,CCDC40,MYH15,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,TLCD1,ARHGAP17,AKAP8L,SSFA2,KIRREL2,ANKRD33B,VIM,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,IFT81,LMBR1L,KLF4,ATG7,INTS9,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,RFX1,VARS,RBM19,FOXP1,POGZ,ANKRD54,SURF2,TMEM161A,POLR1B,CPNE7,TRNP1,AP4S1,LRRIQ1,MON1A,SMARCAD1,C22orf34,ABCF2,KRTCAP3,ARHGEF12,RANGAP1,YIPF3,PALLD,C8orf33,SMPDL3B,POLR3A,CDH24,CACNB1,SAMD5,DSC2,TAF4,TBX3,CSRNP1,BCAS3,USP20,TMEM219,RBPJ,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,PRKCA,LRP5L,ZFYVE28,CSGALNACT2,SPAG6,ZNF646,ACADS,GDAP1,OSBP2,C2orf76,CAMSAP2,ZDHHC14,SON,CLNS1A,GZF1,SPOP,DOT1L,TRRAP,SH3RF1,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,CFD,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,RFXAP,SPOCK3,SPOCK2,PRPF38B,CDC42EP2,JUP,LARS2,DLGAP4,PRPF39,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,USPL1,SCAF1,MYC,PIGG,MFAP2,RTFDC1,IFNGR2,RREB1,PRIM2,PCCA,RAP1GAP2,RDH10,ARID1A,EHBP1,ANGPTL4,SLC26A11,PHF6,ATP9B,ASCC3,ALKBH3,HIF1A,VCAN,SPEN,SRP68,MED15,SQLE,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,SYT17,BIRC6,UROD,KIAA0232,TMEM104,PLEK2,POP5,PTPRG,CORO6,FLNB,IGSF1,RING1,NOP56,BLOC1S2,NUBPL,SLX4,ARMC6,PPID,DTNBP1,TTC3,CMPK1,CDK12,BRD4,GON4L,PCMT1,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,ERC1,HSD3B7,DNTTIP1,SMARCC1,WDR5B,G6PD,LARGE,IFT140,SLC4A7,CBWD1,TBXA2R,SETD6,MID1,FGFBP3,SSH2,NOSTRIN,BRAF,B4GALT5,KIF5C,DNAJC22,OPA1,GIGYF2,FAM8A1,ABL1,ELP5,DYNC2H1,ERRFI1,NAV3,TMC7,SLC40A1,PXN,TTLL5,PSAT1,APEX1,ZFYVE1,ADSL,PACS1,BMS1,KLF6,SLC23A2,RETSAT,DDX50,ZNF155,IREB2,COQ9,ATM,SVIL,APAF1,IPO4,ZNF76,LETM1,EIF3C,ATRX,RARS2,SLC52A3,SLC30A7,PCYOX1L,DST,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,CARM1,CEP128,SRPK2,DTNB,TNK2,DEAF1,SKAP2,SIRT6,ITPA,TFPI,KSR2,MTHFD1L,SGK2,KMT2C,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,CSMD3,ASB3,CLU,DCAF5,RHOBTB1,VTA1,PCSK7,SMG7,QSER1,EVPL,ELL,ZNF354A,ISPD,LRP3,ATP6V0D1,AKAP11,MTHFD1,ZNF234,PPAT,TRA2A,JMJD1C,ZBED4,LIG4,CORIN,SYT1,AGAP1,SYCP2L,BICD1,KIAA0355,FAT1,KIAA0754,FDPS,TMEM117,CDKAL1,SLC16A1,IFITM2,TBCK,FNBP1L,PDE9A,DMXL2,FEZ2,TMEM183A,PIGH,TNXB,SMARCA4,TBCCD1,SPATS2,PIBF1,RIOK2,ZC3H13,RRN3,KCTD11,PPFIBP1,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,GNG5,MAML3,NPW,ANTXR2,PRAME,ATXN1,POU2F1,DKC1,UBR4,BATF3,ARMC4,ALAD,KPNA3,IKZF4,DUS3L,HNRNPR,ZNF557,CEBPZ,WDR73,ARNTL,FKBP5,TMEM101,ARC,RNF130,NFRKB,BRD9,SMG1,TMCC1,BCKDK,SUPT6H,PDE4B,CHCHD10,MED18,SEMA3E,SOGA1,ENOX1,MFHAS1,BMP6,PEX7,SCN1B,STC2,DCTN4,LDLRAD3,PKNOX1,MICAL3,RPS6KB2,MARCH9,KDM6B,SLC6A16,DNMBP,FGF2,CRIM1,KDM5A,SCFD2,SCMH1,ZNF324B,PDE2A,TMEM187,EIF5B,NAALADL2,ZNF221,DAGLB,WDR35,AGTPBP1,ANKRD30BL,NFKBIB,ZSWIM6,GNB3,ASCC1,CACNA1H,CSPP1,HLTF,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,SREBF2,NSRP1,SYN2,PMAIP1,RASSF3,RABGAP1L,PDS5B,ZNF148,HRG,CNTNAP3B,WLS,PTPRM,RFX2,AKAP12,PLEKHM3,C10orf76,RBM28,STOML2,DDX3X,BRCA2,TMEM139,MEF2C,HERC2,CARS,TNNC1,EP400,CLDN15,TRIP6,KHDRBS1,NHS,RSF1,CLINT1,SLC1A1,YARS2,ABCA7,SH2B3,DDX56,EIF2S2,KIAA1671,SLC38A5,CACNB2,ANP32B,AGL,MAP3K12,FMNL2,FADS1,COL17A1,RB1CC1,TSPYL4,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,NCDN,VPS13C,LRP1B,LEMD3,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,TRERF1,DDX18,ATP6V1A,NPAS2,BTBD2,PDK4,MYH9,AGAP6,SAFB2,EEA1,STAM,HSPA1A,PRKD3,BCAS2,ABCA12,ERI1,PYCRL,FMNL1,NT5C,MTHFD2L,LSM10,PERP,MALL,GARS,KRT7,FAM111B,NPM3,ARHGEF10,TTC28,FGFR1,PDE8B,HLA-DMA,TAF2,CDC16,HIPK2,WDR7,FUS,BRCC3,ANKS1A,LAMA5,YEATS2,TRIM36,ZNF786,XPC,SESTD1,TRAK1,ID2,SF3A3,BHLHE40,TGFB2,MBNL1,POM121,KRI1,NPRL2,GATC,SUV39H2,PVRL3,ACAP3,HNRNPM,ULBP1,DIS3L2,DDHD1,FAM98A,CLYBL,ARHGAP39,MRPS10,R3HDM2,FAM126B,ZNF467,FOXC1,RPA1,KISS1R,ETFDH,TRIB3,BAZ2B,PXDN,POLE2,ARID3B,PLPPR2,STX1A,PTPN4,SLC25A19,SLCO5A1,PSAP,GPAM,IGBP1,DOCK6,KDM4C,SRM,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,RNF43,TMEM132A,TTI1,SEC16A,BIRC2,ABL2,ARHGAP18,PHKA1,PPCDC,UBAP2L,ZNF85,RAN,ETV1,PTPRK,SF3A1,FLNC,CHD9,GCNT2,SLC3A2,ABCC4,HARS,ZNF414,KATNAL1,GDPD1,MED27,NOL6,ATG12,BRCA1,ZNF91,PEX1,TOM1L2,TP53BP1,PER1,EEFSEC,TECPR2,CCDC146,TNFRSF1A,RAD51B,SGSM2,RNF214,TMEM158,CHMP4C,XYLB,NOMO3,OXNAD1,AOC3,HES6,ZFP36L1,DNAH1,RNF40,KIAA1958,ABCA5,SAMD11,GMDS,ALDH18A1,NT5E,CAMKK2,LAMC1,TLE3,HOMER2,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,VAC14,PGD,ATXN7,SPAG9,ITPRIPL1,FAM135A,PALB2,SYNCRIP,DNAH17,ZNF430,ARHGAP12,PRKAR2A,NDUFA5,CYLD,RSL1D1,ZNF83,RPAIN,PELP1,CAD,UBR1,FSIP2,ARMC5,CYB5D1,C15orf40,ZDHHC6,ETF1,RNF2,ANO8,ZFP37,CORO1A,AKNAD1,PRMT3,CTC1,TMEM200A,KAT8,SKIV2L,WDR36,GLTSCR2,CPOX,AKAP13,ENC1,NUP214,USP36,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,CLEC16A,ZNF333,ITGA2,ZNF436,PUS1,NFASC,ZNF589,ATXN7L2,UNC13D,MAP3K13,ARFIP2,C14orf159,MAP1S,ZNF346,C15orf57,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,ANXA7,IFIT5,PRICKLE2,HIST2H3D,GREB1,DDX31,CD44,PCK2,FBXO31,HSD17B12,ADAMTSL3,ZNF654,DHX34,TEX14,PEAR1,HIST1H4J,GPNMB,RHOT2,PIK3CB,ARMC3,GPC2,SRBD1,MSH3,GLG1,EIF2S1,ITGB4,MIPOL1,GCSH,MYCBP2,POLB,CGN,TNFRSF21,TMEM109,ENAH,UBR5,AARS,MGA,GIPR,RPS16,VPS52,PAK1IP1,RNF111,CEP135,SEH1L,TBC1D8,DDN,DPF3,SETD1B,ATG9A,NOL8,CUX1,TCEB3,SEMA3F,FOXRED1,SKIL,VPS13D,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,DROSHA,CELSR1,ANKRD17,CCDC53,ZHX3,GTF2IRD1,PID1,TGFBR2,PRKCE,NAV1,PI4KB,TSPAN2,ASAP1,COPS3,VWDE,GTF3C3,LPCAT1,PRPS1,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,KIAA0586,TTYH2,PLCB1,ARIH2,DAGLA,EPRS,KIDINS220,SERF2,SRRD,UBAP1,PMEPA1,ZZEF1,ZBTB12,D2HGDH,PURB,UMPS,IQSEC2,MACROD1,MAP2K4,ZFHX2,RTTN,PTCD2,TBKBP1,AMOTL1,TRPM2,URB2,HFM1,C1QTNF7,SPATS2L,FOSL2,AP1B1,LTB4R,TRIM66,PDE3A,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,SHC1,KDM2A,GLYR1,SSBP1,SERPINH1,KMT2A,ZCCHC14,MTIF2,WDPCP,DLG4,GALK2,MED16,PNN,TBC1D16,STK10,DHX57,CPED1,DCBLD2,VDR,YIPF2,DNAJA3,ZNF236,H2AFX,ALKBH1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,CA11,UTP14A,TTC27,C10orf2,TCF3,MRI1,ZNF280C,NFX1,SLC25A12,MYNN,MON2,MLH1,IKBKAP,GDPD5,FOXO3,NEDD4,ZNF483,LRP2BP,NISCH,UPF2,NLGN3,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,OASL,MMAA,ECH1,ZDHHC11,HELZ,STX18,RNF138,MYOM2,PGAM5,BRWD3,LRRC41,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,FANCD2,PLOD1,ZNF107,ANKRD18A,SLC29A1,BCOR,SNAPC4,MRPS30,SMARCB1,RTN1,SRPRB,ZNF804A,ANAPC1,RAP1A,YLPM1,THADA,LONRF2,ATG3,GPR87,POLR3B,PCOLCE2,SLC27A5,TRIM14,TRIP13,LONP1,ELOF1,ZBTB17,LAMA4,TRIM13,CMIP,ZNF680,HDAC8,ZSCAN2,TCTN1,CHAF1A,RHOU,GEMIN5,TMEM132B,UBTF,EPN2,GATA6,SUFU,TRMT5,DNAJC1,MKL2,ABCC3,GALNT10,COPS6,DMTF1,TNRC6A,VIPR1,SLC12A7,RELL2,AK2,CHST11,FN1,SEC24D,TAF1,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,TOX4,CEP164,SIPA1L3,ATXN2,BANF1,NRIP1,N4BP2,CPSF3L,VOPP1,KRT20,RANBP6,PDE4A,TSTA3,WBSCR22,WWC1,C11orf65,PRDM1,ANKRD20A4,DNAH14,ISG15,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,HK2,EXOC4,KIAA1328,ZFP90,C7orf26,ZBTB24,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,GBF1,ZSCAN5A,FARSA,BRE,CCDC50,CAMTA2,LYPLAL1,RPS6KL1,ZNF142,CPSF3,MET,TSPAN14,HN1,MCEE,PHLDB2,FAM172A,SFSWAP,R3HDM1,TOR1AIP2,ATP8B2,RAB10,PUSL1,RAD54B,WARS,PLIN2,ZC3H12A,HYAL3,ADNP,SLC25A11,DISP1,SCARB1,HEATR1,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,H2AFJ,NSUN6,CLSTN2,LETMD1,CCDC7,PPP1R1C,SFI1,MAN1A1,IL17RE,CTNNBL1,HAS3,DSG2,KDELC1,CLDND1,AMOT,PAQR6,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,MEN1,LENG8,ZNF407,MFN2,RERE,HSPA1B,ZNF708,CUL2,ZRANB2,MBD6,PREPL,MMP16,HRH1 |
| 1.177e-02 | -4.44 | TCCAGAT,MIR-516-5P | MSigDB lists | TCCAGAT,MIR-516-5P | 104 | 22 | 17758 | 2279 |
DBN1,SNX27,BRD4,CLK1,OLA1,GMFB,RAP1B,LRRC8A,ATXN1,WDR26,ADAMTS6,ARHGEF12,CCDC47,SLC1A1,DDX3X,SPAG9,UBAP2,SH3RF1,IQSEC2,MMP16,TIMM50,ATXN7L2 |
| 1.179e-02 | -4.44 | MCM_2 | prosite domains | PS50051 | 8 | 4 | 11866 | 1504 |
MCM6,MCM2,MCM9,MCM5 |
| 1.179e-02 | -4.44 | S1 | prosite domains | PS50126 | 8 | 4 | 11866 | 1504 |
EIF2S1,SRBD1,SUPT6H,PDCD11 |
| 1.180e-02 | -4.44 | ATAGGAA,MIR-202 | MSigDB lists | ATAGGAA,MIR-202 | 98 | 21 | 17758 | 2279 |
TCF12,EIF4E3,LUZP1,GPBP1L1,MED13L,SMG7,ATXN1,ENAH,MEX3B,SSBP2,UBE2K,TGFBR2,DDX3X,ZFAND3,ANKRD13A,ASAP1,LEMD3,CNOT6,LDLRAD3,NR2F2,USP15 |
| 1.182e-02 | -4.44 | CDK6 (cyclin-dependent kinase 6) | protein interactions | 1021 | 117 | 26 | 16036 | 2270 |
MCM10,TRA2A,CDK4,TRAK1,PPHLN1,RCHY1,ATXN1,SSBP2,MEF2D,MCM2,FOXO3,POGZ,LPIN1,EIF4ENIF1,SRSF2,CLASRP,CCNT1,MYC,ZEB1,SENP3,RUNX1,WDR33,CDK6,RTFDC1,DDIT3,CDC37 |
| 1.184e-02 | -4.44 | - | gene3d domains | 1.10.730.10 | 11 | 5 | 9988 | 1398 |
MARS,VARS,RARS,LARS2,RARS2 |
| 1.185e-02 | -4.44 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP | 179 | 34 | 17758 | 2279 |
MYCBP2,ARL15,ST6GAL1,UROD,DOPEY1,SIPA1L3,DSG2,CMPK1,MPST,SRPK2,SPTAN1,RPS6KB2,KDM3B,KAT8,PFKFB4,KDM5B,JMJD1C,GNG7,SUMO3,ATP6V0A1,C11orf49,EDEM2,ZNF467,PDE2A,NUP214,ZNF251,MKL2,BDH2,ZCCHC6,LARGE,PTPN4,PPIL3,RFXAP,DCAF5 |
| 1.187e-02 | -4.43 | MODULE_198 | MSigDB lists | MODULE_198 | 297 | 52 | 17758 | 2279 |
TCF12,MCM6,KHDRBS1,CSNK2A1,ZFP36L1,MLH1,HLTF,SNW1,SRSF2,HR,VPS72,MYC,RAN,CMPK1,TRIP13,TMPO,SRPK2,CLK2,SAP30,RFC4,MSX1,RFC3,ZNF124,ATF4,PRIM2,APEX1,ZNF195,RNMT,STAMBP,POLA1,TSN,WBSCR22,LIG4,PNN,SOX4,DSP,CHAF1A,ZBTB25,RPA1,RBBP8,SMARCC1,POLE2,HIF1A,CCNT1,HNRNPR,PER1,TAF4,H2AFX,NCBP2,FKBP5,BMI1,BLMH |
| 1.187e-02 | -4.43 | actin monomer binding | molecular function | GO:0003785 | 25 | 8 | 16491 | 2164 |
ABL1,PRKCE,ABL2,TMSB10,LIMA1,COBLL1,CORO1A,TMSB4X |
| 1.187e-02 | -4.43 | cyclic-nucleotide phosphodiesterase activity | molecular function | GO:0004112 | 25 | 8 | 16491 | 2164 |
PDE4A,PDE10A,PDE4B,PDE2A,PDE3B,PDE9A,PDE3A,PDE8B |
| 1.196e-02 | -4.43 | RNF139 (ring finger protein 139) | protein interactions | 11236 | 19 | 7 | 16036 | 2270 |
INSIG2,HM13,SREBF2,INSIG1,COPS5,AUP1,HMGCR |
| 1.196e-02 | -4.43 | SAR1A (secretion associated, Ras related GTPase 1A) | protein interactions | 56681 | 19 | 7 | 16036 | 2270 |
SEC31A,ATXN1,TRAF3,HMBS,CUL7,FN1,MTHFD1 |
| 1.196e-02 | -4.43 | Bcl7b (B cell CLL/lymphoma 7B) | protein interactions | 12054 | 19 | 7 | 16036 | 2270 |
SMARCA4,ARID1A,SMARCC1,ARID2,ARID1B,DPF2,SMARCB1 |
| 1.196e-02 | -4.43 | TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein) | protein interactions | 26133 | 19 | 7 | 16036 | 2270 |
RIPK1,CUL4A,COPS5,MYC,IKBKB,CHMP4C,TNFRSF1A |
| 1.196e-02 | -4.43 | CPSF4 (cleavage and polyadenylation specific factor 4) | protein interactions | 10898 | 19 | 7 | 16036 | 2270 |
RANGAP1,WDR33,FIP1L1,SYMPK,CDC73,CLK2,RRAGA |
| 1.196e-02 | -4.43 | CD3EAP (CD3e molecule, epsilon associated protein) | protein interactions | 10849 | 19 | 7 | 16036 | 2270 |
UBTF,RNF2,POLR1B,POLR1C,NFKBIB,POLR1E,POLR1A |
| 1.197e-02 | -4.42 | histone acetyltransferase complex | cellular component | GO:0000123 | 87 | 19 | 17570 | 2233 |
KAT8,WDR75,EP400,ELP3,SUPT20H,IKBKAP,TAF9B,TADA3,TAF2,ATXN7,TRRAP,ELP2,KANSL1,TAF4,UBAP2L,POLE3,TAF12,YEATS2,KAT6A |
| 1.200e-02 | -4.42 | GSE17721_CTRL_VS_LPS_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDM_UP | 192 | 36 | 17758 | 2279 |
SEC24D,UBXN1,OLA1,SLC39A11,SKI,PRKCH,CTNNBL1,APLF,ATG3,RASSF3,NCKIPSD,METTL8,DTNBP1,SOCS6,CTR9,KIAA0922,TSPAN14,TMEM14C,FAM98A,ZNF124,CRADD,CMIP,CLNS1A,RERE,TPK1,MLLT10,MRPL36,BSN,RPL28,SRP68,MPV17,CDKAL1,NCOR1,KLHDC4,TXN2,NIT1 |
| 1.200e-02 | -4.42 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | 192 | 36 | 17758 | 2279 |
AOC3,CYLD,ITPRIP,LPCAT2,AMBRA1,SYN2,ATXN2,WAC,ETF1,CDK12,SLC25A1,ACSL5,DDHD1,VOPP1,VPS37A,SETD1B,SIRT6,MYO10,ZNF654,EPS15L1,GDPD1,C1QTNF1,GNL1,AKAP13,ZNF467,DNAJC1,SPEN,TMEM219,PRPF4,APAF1,IFITM2,CCNB1IP1,SLC16A10,CTXN1,TRIM36,LRRC41 |
| 1.200e-02 | -4.42 | GSE17721_CTRL_VS_CPG_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_8H_BMDM_UP | 192 | 36 | 17758 | 2279 |
CERS5,C14orf159,PIP4K2A,PABPC4,SKI,CTNNBL1,RASSF3,ACOT11,CORO1A,AGL,TMEM14C,RPS6KB2,MCEE,KLRD1,SOBP,ZNF124,TUBA1A,TFCP2,LIMA1,RAB7A,SMARCAD1,TMEM216,TPRA1,NEU1,PGD,HLA-DMA,ELP2,LUC7L3,HNRNPH3,FDPS,CDKAL1,GPAM,HMBS,MTMR1,TSPAN5,SYNPO |
| 1.200e-02 | -4.42 | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 192 | 36 | 17758 | 2279 |
SARS,PRPF31,WDR37,HLTF,XPO7,IKBKAP,CLINT1,CUTC,PITPNM1,ZNF354A,COPS3,LTN1,TTC3,ANP32B,TBC1D8,PFKFB4,CHD9,WDR61,RREB1,DDX41,NARS,IDH3G,TSN,PPIP5K2,DKC1,RPA1,ZFAND3,KIDINS220,HNRNPH3,FAM206A,MBTD1,ACP1,NFRKB,RNF130,PTP4A2,TXN2 |
| 1.200e-02 | -4.42 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | 192 | 36 | 17758 | 2279 |
CHST11,B4GALT5,SMAD7,SPATS2L,GYG1,BHLHE40,DENND3,CD226,MAN1A1,TSPAN2,RABGAP1L,JAZF1,LPCAT1,PRF1,SAP30,KLRD1,SESN2,PDE4A,AGPAT4,KATNAL1,RAP1GAP2,PREX1,LGALS1,ATXN1,TTYH2,ZDHHC14,SMAD3,RHOU,AHNAK,DNAJC1,TTC38,PAM,PTPN4,ANXA2,PTP4A2,LPP |
| 1.200e-02 | -4.42 | GSE7852_THYMUS_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TCONV_DN | 192 | 36 | 17758 | 2279 |
EFNB2,MIF4GD,DNAJA4,LUZP1,SEC24D,SPRYD7,KIF5C,ATXN7L1,CAMTA2,SLC38A2,ACOT11,TMEM14C,PNMA1,ANTXR2,ZCCHC14,CRIM1,AGPAT4,HSPA5,LGALS1,TBRG4,CAV1,AKAP13,ODC1,CPT1A,DENND4A,PHF6,BTBD11,ARHGAP21,C20orf196,ARL4A,CFD,CASS4,SLC4A7,SQLE,ANXA2,IFITM2 |
| 1.200e-02 | -4.42 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 192 | 36 | 17758 | 2279 |
EFNB2,SPRED2,FEZ2,EGR1,ATP6V1A,TNFRSF21,CSNK2A1,RMI1,IGF2BP3,DSG2,RAN,AVEN,C12orf4,SLC25A1,MYB,SAP30,PTPRK,DNMBP,TFPI,KIF15,MARCKSL1,C11orf49,ARHGAP32,BRCA1,EXOG,NUP214,ST3GAL5,IFT81,PDLIM1,TP53BP1,FAT1,FDPS,PTP4A2,USP11,ECHDC1,HS2ST1 |
| 1.200e-02 | -4.42 | GSE339_CD4POS_VS_CD8POS_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_DN | 192 | 36 | 17758 | 2279 |
SLC12A7,ZNF706,CUL4A,ARID2,VTA1,PTPRA,SLK,PLA2G12A,TUBB6,REEP5,ANXA10,TOX4,PHC2,RNF141,FKBP1A,NEK6,PSMG4,THAP4,ETF1,CLDND1,PPA1,MYB,DTNB,HSPA5,TCEB3,KRTCAP2,ODC1,MAT2A,HERPUD1,CAT,HTR7,AHNAK,ARID3B,HIPK2,UMPS,PKIB |
| 1.201e-02 | -4.42 | V$SRF_Q6 | MSigDB lists | V$SRF_Q6 | 231 | 42 | 17758 | 2279 |
TNNC1,EGR1,NPAS2,PRKAB2,ACTR3,RSF1,FOXP1,MBNL1,PCDH7,TADA3,ABL1,RAP1A,NAV1,ZEB1,VCL,AGL,BDNF,MSX1,ATF4,PPARG,TLE3,NPM3,TMEM126A,SETD2,LDHA,PRDM1,KRTCAP2,KLF6,NR2F1,RERE,SLC7A1,SYNCRIP,HERC1,HOXA3,H2AFX,SVIL,CSMD3,NR2F2,PDLIM5,ZAK,KIF1B,LPP |
| 1.202e-02 | -4.42 | monocyte differentiation | biological process | GO:0030224 | 16 | 6 | 16441 | 2138 |
MYH9,THOC5,BMP4,PDE2A,PPARG,MEF2C |
| 1.202e-02 | -4.42 | positive regulation of histone H3-K4 methylation | biological process | GO:0051571 | 16 | 6 | 16441 | 2138 |
CTR9,SNW1,BRCA1,WDR61,KMT2A,MYB |
| 1.202e-02 | -4.42 | regulation of inclusion body assembly | biological process | GO:0090083 | 16 | 6 | 16441 | 2138 |
SACS,CLU,DNAJA4,DNAJB6,HSPA1A,HSPA1B |
| 1.203e-02 | -4.42 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | 63 | 15 | 17758 | 2279 |
GLS,FADS1,SUB1,ATRX,ST6GAL1,GNG7,SLC38A2,GTF2IRD1,MARS,PRDM1,CAV1,BMI1,RAB30,TAF9B,MYB |
| 1.205e-02 | -4.42 | ovary-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | ovary-carcinoma-undifferentiated_carcinoma | 41 | 11 | 17775 | 2278 |
BRCA2,BRAF,NRAS,NF1,SMARCA4,ATM,RNF43,BRCA1,ARID1A,MET,FGFR1 |
| 1.207e-02 | -4.42 | mRNA cleavage and polyadenylation specificity factor complex | cellular component | GO:0005847 | 12 | 5 | 17570 | 2233 |
FIP1L1,WDR33,CPSF3,CSNK1A1,ZC3H3 |
| 1.207e-02 | -4.42 | npBAF complex | cellular component | GO:0071564 | 12 | 5 | 17570 | 2233 |
SMARCA4,SMARCD3,ARID1A,SMARCC1,SMARCB1 |
| 1.209e-02 | -4.42 | PRPF4 (pre-mRNA processing factor 4) | protein interactions | 9128 | 84 | 20 | 16036 | 2270 |
SART1,SNU13,FN1,GPHN,KDM5B,PRPF31,CLK1,TFIP11,PLRG1,EPS15L1,SF3A3,UBC,SNW1,DHX37,PRPF4,CDK12,N4BP2L2,SF3A1,PRPF19,USP15 |
| 1.209e-02 | -4.42 | protein modification by small protein conjugation or removal | biological process | GO:0070647 | 843 | 132 | 16441 | 2138 |
MYCBP2,CUL7,CUL4A,FEM1C,HECTD3,RCHY1,RNF43,BCOR,HLTF,NUP160,BIRC2,UBR5,ANAPC1,COPS4,ATG3,ANAPC11,ANAPC10,TRIML2,IPP,RNF111,SEH1L,TRIM13,RBCK1,KLHL23,MED27,TCEB3,SUMO3,DCUN1D5,BRCA1,SPOP,PAF1,UBE3D,TRRAP,RAD18,SH3RF1,NSMCE1,SOCS4,ASB3,CCNB1IP1,COPS6,BMI1,BLMH,DCAF5,USP15,FBXO45,CTU2,HERC2,CDC73,RNF40,RNF141,UBE3A,USPL1,COPS3,PPIL2,MED24,CTR9,CNOT4,LRSAM1,ANAPC13,STAG1,USP49,PSMA1,USP10,TRIM37,USP46,ARIH2,UBE2E1,ATXN7,SENP3,C18orf25,RNF114,USP7,CYLD,BIRC6,KLHL18,RNF24,NUP43,RING1,PHC2,KCTD11,SOCS1,UBR1,NUP133,UCHL5,WAC,SOCS6,RNF2,TTC3,PRPF19,STAMBP,MARCH6,ENC1,NUP214,UBR4,USP36,FBXL5,RANBP2,CDC16,COPS5,NSMCE2,ATG7,TRAF3,MED20,RNF130,USP11,BRCC3,XRCC4,TRIM36,KLHL24,XPC,TRIM22,PSMF1,POM121,NEDD4,LTN1,COPS7B,FBXO31,FBXL19,MARCH9,USP42,SCMH1,UBE2K,UBC,RPA1,FBXO21,KLHL22,HERC1,CUL2,RNF138,USP20,ANAPC4,LRRC41 |
| 1.209e-02 | -4.42 | Acyltransferase | pfam domains | PF01553 | 16 | 6 | 16629 | 2165 |
GPAM,LCLAT1,LPCAT1,LPCAT2,AGPAT4,GPAT3 |
| 1.211e-02 | -4.41 | CAGCCTC,MIR-485-5P | MSigDB lists | CAGCCTC,MIR-485-5P | 135 | 27 | 17758 | 2279 |
MSI2,HMGA2,TBKBP1,CHD9,SSH2,LIN28B,ITPRIP,BAZ2A,SETD2,TTYH2,IGF2BP2,ARHGAP32,MEF2D,TNKS1BP1,DHX57,MAN1A1,SLC23A2,OXSR1,NRF1,DNAJA3,TRMU,HIC2,NBEA,COPS7B,HTRA2,SMG1,TMCC1 |
| 1.217e-02 | -4.41 | NUCLEAR_MEMBRANE_PART | MSigDB lists | NUCLEAR_MEMBRANE_PART | 41 | 11 | 17758 | 2279 |
RANBP2,RETSAT,KPNA1,KPNA3,NUP133,LEMD3,RANGAP1,XPO7,NUP214,DHCR7,NUP160 |
| 1.217e-02 | -4.41 | REACTOME_G2_M_CHECKPOINTS | MSigDB lists | REACTOME_G2_M_CHECKPOINTS | 41 | 11 | 17758 | 2279 |
RFC4,RFC3,MCM6,MCM10,MCM5,ORC5,DBF4,ATM,ATRIP,MCM2,RPA1 |
| 1.217e-02 | -4.41 | AMIT_EGF_RESPONSE_480_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_480_MCF10A | 41 | 11 | 17758 | 2279 |
TRIB3,CHST11,SRRD,PMAIP1,ITGA2,PLEK2,ODC1,TIMM10,PHLDA2,GIT2,NAV3 |
| 1.217e-02 | -4.41 | human chr17q25.1 | chromosome location | human chr17q25.1 | 81 | 15 | 26250 | 2590 |
UNC13D,MIF4GD,SRSF2,C17orf80,GRIN2C,TMEM94,ACOX1,SRP68,METTL23,TTYH2,TMEM104,NT5C,EVPL,SAP30BP,HN1 |
| 1.219e-02 | -4.41 | human chr18q12.2 | chromosome location | human chr18q12.2 | 10 | 4 | 26250 | 2590 |
C18orf21,KIAA1328,ZNF397,ELP2 |
| 1.219e-02 | -4.41 | human chr12q14 | chromosome location | human chr12q14 | 10 | 4 | 26250 | 2590 |
LEMD3,CDK4,RAP1B,USP15 |
| 1.219e-02 | -4.41 | human chr12q24.22 | chromosome location | human chr12q24.22 | 10 | 4 | 26250 | 2590 |
RNFT2,FBXO21,LINC00173,TESC |
| 1.220e-02 | -4.41 | endoribonuclease complex | cellular component | GO:1902555 | 21 | 7 | 17570 | 2233 |
RPP30,POP1,POP5,DROSHA,TSEN2,AGO3,AGO2 |
| 1.220e-02 | -4.41 | podosome | cellular component | GO:0002102 | 21 | 7 | 17570 | 2233 |
SVIL,PTPN12,RHOU,FSCN1,SH3PXD2A,SH3GL1,TPM4 |
| 1.220e-02 | -4.41 | carboxy-terminal domain protein kinase complex | cellular component | GO:0032806 | 21 | 7 | 17570 | 2233 |
GTF2H1,SNW1,GTF2H3,BRD4,CCNT1,CDK9,KDM5A |
| 1.221e-02 | -4.41 | aa-tRNA-synt_IIb | interpro domains | IPR002314 | 8 | 4 | 18293 | 2341 |
EPRS,SARS,GARS,TARS |
| 1.221e-02 | -4.41 | PH-BEACH_dom | interpro domains | IPR023362 | 8 | 4 | 18293 | 2341 |
NBEA,NBEAL1,WDFY3,LYST |
| 1.221e-02 | -4.41 | VPS13_N | interpro domains | IPR026854 | 8 | 4 | 18293 | 2341 |
VPS13D,ATG2B,VPS13C,VPS13B |
| 1.221e-02 | -4.41 | MCM | interpro domains | IPR031327 | 8 | 4 | 18293 | 2341 |
MCM6,MCM2,MCM9,MCM5 |
| 1.222e-02 | -4.41 | AIFM1 (apoptosis-inducing factor, mitochondrion-associated, 1) | protein interactions | 9131 | 68 | 17 | 16036 | 2270 |
CPOX,BCS1L,WWC1,MLH1,HSPA1A,ISG15,HSPA1B,OXSR1,SHC1,FSCN1,COPS5,STC2,CUL2,H2AFX,RNF2,BMI1,RPS6KB2 |
| 1.222e-02 | -4.40 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | 225 | 41 | 17775 | 2278 |
DMXL2,CACNA1H,DHX35,YARS2,IGSF1,ZNF608,NAV1,SIPA1L3,SLX4,FUT11,NUDC,NRAS,TTLL5,CRIM1,THSD4,SETD2,GRHL3,NLN,ATP6V0A1,WWC1,BRCA1,PRDM1,LAMA2,EDEM2,PPIP5K2,PLCB1,MMAA,BTBD11,DDX3X,GRIK4,FAM135A,GSTO2,ADNP,EXOC4,CTAGE5,VPS13D,ATM,CSMD3,HEATR1,IPO4,LMBRD2 |
| 1.223e-02 | -4.40 | exoribonuclease activity, producing 5'-phosphomonoesters | molecular function | GO:0016896 | 30 | 9 | 16491 | 2164 |
TOE1,EXOSC2,ERI1,CNOT6,EXOSC4,ERI3,NOCT,PARN,DIS3L2 |
| 1.226e-02 | -4.40 | UBE2I (ubiquitin conjugating enzyme E2I) | protein interactions | 7329 | 406 | 74 | 16036 | 2270 |
SART1,SLC2A1,NAT10,MYH9,SEMA6A,HNRNPLL,KDM1A,NOP56,SKI,SREBF2,SOCS6,RNF111,FHIT,ETV1,ZMYM2,ZNRD1,CASP8AP2,CARM1,ZNF646,CDC37,PPARG,NOL6,SUMO3,ATXN1,CAMSAP2,BRCA1,SOX4,RAD54B,SKIL,RANBP2,RAD18,TP53BP1,CHD3,HIPK2,ARL13B,TNFRSF1A,TRAF3,FUS,BMI1,BLMH,MEF2C,NCOR2,TAF1,TCF3,UBXN1,ATF7IP,JMJD6,XPO7,BHLHE40,RNF40,MYC,ZCCHC7,HNRNPM,SOX6,MYB,CLK2,TOP1,DDX24,APEX1,MAPK1IP1L,RANGAP1,UBE2K,SYMPK,NOP58,UBE2E1,TCF7L2,ANXA1,ATXN7,MYBBP1A,HIF1A,TAF12,NCOR1,TATDN1,C18orf25 |
| 1.227e-02 | -4.40 | SHTN1 (shootin 1) | protein interactions | 57698 | 28 | 9 | 16036 | 2270 |
SEC24A,PSAT1,NME7,TFCP2,UBXN1,TPM4,TPM1,AHCYL1,NEDD4 |
| 1.227e-02 | -4.40 | GLMN (glomulin, FKBP associated protein) | protein interactions | 11146 | 28 | 9 | 16036 | 2270 |
FKBP1A,CUL7,CUL4A,CUL2,FKBP5,IMPDH2,MET,CDC37,NT5E |
| 1.227e-02 | -4.40 | SYMPK (symplekin) | protein interactions | 8189 | 28 | 9 | 16036 | 2270 |
SSU72,SMARCAD1,SIRT7,WDR33,CPSF3,KMT2A,KAT6A,TOP1,RPA1 |
| 1.227e-02 | -4.40 | EXOC4 (exocyst complex component 4) | protein interactions | 60412 | 28 | 9 | 16036 | 2270 |
EXOC1,MYC,DLGAP4,DTNBP1,DLG4,ATG12,CEP63,TPM1,EXOC6 |
| 1.227e-02 | -4.40 | VSIG2 (V-set and immunoglobulin domain containing 2) | protein interactions | 23584 | 28 | 9 | 16036 | 2270 |
THADA,DYM,LEMD3,XPO5,TNPO3,XPO7,TTI1,XPO6,COG5 |
| 1.227e-02 | -4.40 | CETN2 (centrin 2) | protein interactions | 1069 | 28 | 9 | 16036 | 2270 |
POLB,BCKDK,XPC,USP49,APLF,EIF4A2,IMPDH2,DNAH14,SFI1 |
| 1.227e-02 | -4.40 | WIPI2 (WD repeat domain, phosphoinositide interacting 2) | protein interactions | 26100 | 28 | 9 | 16036 | 2270 |
TERF2IP,FLNC,DPH1,COPS5,BCAS3,ATG12,RABAC1,COPS6,NUDC |
| 1.228e-02 | -4.40 | DTNBP1 (dystrobrevin binding protein 1) | protein interactions | 84062 | 123 | 27 | 16036 | 2270 |
DTNB,BCAS4,PCNT,STX8,CCDC53,KIF5A,EXOC6B,OSBPL9,ARFIP2,BLOC1S4,VPS53,EXOC6,IQGAP2,BLOC1S2,SFR1,DST,EXOC1,BRCA2,NAV1,RBSN,KANSL1,CEP290,CCDC146,EXOC4,TSSC1,NBEA,COG5 |
| 1.233e-02 | -4.40 | Formation of RNA Pol II elongation complex | REACTOME pathways | R-HSA-112382 | 44 | 12 | 8202 | 1117 |
GTF2H3,ELL,SUPT4H1,GTF2H2C,CCNT1,CDK9,TCEB3,GTF2H1,NCBP2,SUPT5H,NELFA,POLR2A |
| 1.233e-02 | -4.40 | Formation of HIV elongation complex in the absence of HIV Tat | REACTOME pathways | R-HSA-167152 | 44 | 12 | 8202 | 1117 |
ELL,GTF2H3,SUPT4H1,CCNT1,GTF2H2C,CDK9,TCEB3,GTF2H1,NCBP2,NELFA,SUPT5H,POLR2A |
| 1.233e-02 | -4.40 | RNA Polymerase II Transcription Elongation | REACTOME pathways | R-HSA-75955 | 44 | 12 | 8202 | 1117 |
GTF2H3,ELL,SUPT4H1,GTF2H2C,CCNT1,CDK9,TCEB3,GTF2H1,NCBP2,SUPT5H,NELFA,POLR2A |
| 1.233e-02 | -4.40 | phospholipid biosynthetic process | biological process | GO:0008654 | 222 | 41 | 16441 | 2138 |
SERINC5,PIGM,PIGN,MVK,LPCAT2,GPAT3,PIGH,PIK3R4,PLA2G12A,DPM3,LPCAT3,LCLAT1,SYNJ1,PIP4K2A,LPIN1,IDI1,PI4KB,LPIN2,PIGG,SYNJ2,CPNE7,PNPLA3,MGLL,LPCAT1,FADS1,FGF2,AGPAT4,GPCPD1,PITPNB,PIK3CB,VAC14,TAMM41,ALG5,SERINC1,PEMT,ABHD3,SRD5A3,FDPS,ATM,GPAM,MTMR1 |
| 1.233e-02 | -4.40 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 2864 | 410 | 16441 | 2138 |
ZNF292,THOC5,HLTF,CCNL2,PRKCA,LPAR3,GABPB2,LPIN1,AMBRA1,NOS1AP,SKI,GIPR,TOM1L1,SREBF2,ZFHX3,PMAIP1,WIZ,RNF111,ZNF148,FNIP2,MEIS3,DDN,HMBOX1,NRAS,NR6A1,GNL3,EYA3,NFIA,TCEB3,CUX1,AKAP12,C5AR1,SUPT20H,DCUN1D5,STOML2,DDX3X,DDAH2,BRCA2,SUPT4H1,CCNT1,ARL6IP5,FIS1,DIRAS1,RUNX1,NRP1,BMI1,RFXAP,P2RY11,MEF2C,BANP,EPM2AIP1,IFT57,EGR1,JUP,SLK,KHDRBS1,SIRT7,PIK3R4,PID1,RSF1,TGFBR2,PDCD5,CDC73,ABCA7,RBM20,PRKCE,FKBP1A,UBE3A,ENTPD5,APLF,MYC,MED24,ANP32B,MAP3K12,CAV2,PABPC1,TERF2,MYB,HMGCR,PEA15,GTF2H3,BDNF,SYNGAP1,WDR61,STAG1,RREB1,RB1CC1,PRDM16,ARID5B,RAP1B,SMARCD3,ARID1A,NELFA,ARRDC4,PLCB1,CPT1A,TRIM37,ONECUT2,ABCF1,ARIH2,IRS1,CAT,TASP1,KIDINS220,NSF,HIF1A,CDK9,SPEN,NCOR1,SMYD3,MAP2K5,ZNF516,TRERF1,NPAS2,DDR2,MYH9,FOSL2,HSPA1A,BLOC1S2,TERF2IP,SLX4,SHC1,ACD,WAC,LPIN2,MMP14,KMT2A,PERP,CASP8AP2,KMT2D,BRD4,DLG4,SATB2,MED16,MEF2D,SETD7,STK10,ERC1,SERP1,FGFR1,SNCA,VDR,TAF2,FBXL5,CAMK2D,CDC16,SMARCC1,NSMCE2,DNAJA3,PEMT,HIPK2,H2AFX,RPS6KB1,ANXA2,BRCC3,MID1,HMGA2,INSIG2,BRAF,TCF3,ID2,GAS6,TRIM22,TGFB2,RPS6KA5,FOXO3,PSMF1,MAD2L2,SFR1,TADA3,ABL1,SNW1,TRIAP1,RDX,YBX3,LARP4B,MAP3K14,SAMD4A,SOX6,SPTAN1,MBTPS2,SLC40A1,FGF9,PXN,APEX1,WDFY3,PTK2,IL6R,UBE2K,GUF1,KLF6,FOXC1,UBC,POLR2A,ANXA1,OXSR1,TRIB3,NSD1,ARID3B,APAF1,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,DDIT3,KAT6A,STK4,TRIM16,AAMDC,ATRX,NF1,KMT2E,GPBP1L1,PPARGC1B,PTPRA,RCHY1,SIRT2,HNRNPLL,BIRC2,MAP2K3,SMARCB1,ABL2,ANAPC1,RAP1A,PHF5A,DHX33,ANAPC11,ANAPC10,RELB,ZEB1,PCOLCE2,RAN,ETV1,TRIM14,PRKACB,ZBTB17,DEAF1,TNK2,TRIM13,RBCK1,ATF4,GCNT2,PPARG,CDK4,ARRDC3,HSPA5,SUMO3,BRCA1,CAV1,SOX4,MLLT10,UBTF,DYRK1B,PAF1,HPRT1,ZNF622,TCF7L1,GATA6,INSIG1,TP53BP1,E2F4,PER1,MKL2,SOCS4,TNFRSF1A,ADAM9,CLU,DLX2,ZC3H8,UQCC2,MTCH1,FN1,FOXO1,TAF1,PAX2,NKD2,MAPK8IP3,LAMTOR3,SMAD7,BARX2,TRIM15,ZIC2,RLF,ARID1B,RHBDD1,NAMPT,RNF40,ELL,SUB1,MLX,CEP290,NDRG4,BUD31,GTF2H1,CTR9,VAPB,ICE2,WNT16,NRIP1,LRSAM1,CAMKK2,CRADD,PAXBP1,UTP15,WWC1,PSMA1,EIF2A,SUPT5H,HERPUD1,UBE2E1,TCF7L2,NR2F1,ATXN7,SPAG9,IRAK2,ZFP90,TBL1X,PRKAR2A,TESC,TCF12,ASH1L,CEMIP,NTSR1,SMARCA4,PBX1,RIPK1,PIBF1,PELP1,KDM1A,RRN3,NRF1,BRE,JAG1,CAMTA2,NVL,GRIN2C,IKBKB,MET,SPIDR,CASP10,HTRA2,CTC1,MAML3,PRPF19,MOSPD1,KAT8,DDX41,C1QTNF1,GRHL3,ATXN1,DKC1,ZC3H12A,SMAD3,IKZF4,ADNP,SIX5,COPS5,KLF4,CEBPZ,ARNTL,ATG7,DUSP19,PUS1,HEATR1,SCARB1,PKIB,DNAJC2,TNIK,MINK1,SUPT6H,MAP3K13,CAMK1,AGO2,ATF7IP,PIP4K2A,BMP6,PTPN2,PRKCH,TMEM161A,HAS3,CD44,DMRT1,PKNOX1,RPS6KB2,KDM6B,ARNTL2,MSX1,FGF2,ZNF821,SMARCAD1,KDM5A,MEN1,SYMPK,PIK3CB,HSPA1B,RERE,GADD45A,TBX3,TAF4,CSRNP1,BCAS3,NCBP2,MYRF,RBPJ,TAF12,NFKBIB,NR2F2,ZAK,HRH1 |
| 1.239e-02 | -4.39 | DAGPEDOMAIN | prints domains | PR00008 | 21 | 6 | 4759 | 462 |
CHN1,PRKCE,PRKCH,PRKD3,BRAF,PRKCA |
| 1.239e-02 | -4.39 | V$FREAC3_01 | MSigDB lists | V$FREAC3_01 | 238 | 43 | 17758 | 2279 |
KLHL24,BRAF,TRERF1,SESTD1,VPS45,DLGAP4,ID2,ZIC2,AKT1S1,XPO7,FOSL2,PRPF39,PIP4K2A,ARID1B,POGZ,NEDD4,CHN1,ATXN7L1,NSRP1,ATP5G2,CCDC112,PRICKLE2,KIAA0922,ETV1,CDK6,LRP3,ANGPT2,MAML3,NAV3,FGF9,MPP6,AGPAT4,TBXAS1,KIAA0586,POU2F1,MEX3B,PRDM1,MARCH6,MBNL2,TCF7L2,HERPUD1,HOXA3,TRAF3 |
| 1.243e-02 | -4.39 | S1_dom | interpro domains | IPR022967 | 12 | 5 | 18293 | 2341 |
EIF2S1,EXOSC2,SRBD1,SUPT6H,PDCD11 |
| 1.243e-02 | -4.39 | Mab-21_dom | interpro domains | IPR024810 | 12 | 5 | 18293 | 2341 |
ITPRIPL1,ITPRIP,MB21D2,MIEF1,MAB21L3 |
| 1.243e-02 | -4.39 | JAMM/MPN+_dom | interpro domains | IPR000555 | 12 | 5 | 18293 | 2341 |
COPS6,BRCC3,STAMBP,COPS5,EIF3H |
| 1.243e-02 | -4.39 | PRTase-like | interpro domains | IPR029057 | 12 | 5 | 18293 | 2341 |
UMPS,APRT,HPRT1,PPAT,PRPS1 |
| 1.243e-02 | -4.39 | GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN | 186 | 35 | 17758 | 2279 |
SEPHS2,SH2D3A,NDUFB5,PRKCA,INPP1,REEP5,PABPC4,SRPRB,ADH5,ASNS,NISCH,AGL,ACTR3B,PNMA1,SF3A1,RABEPK,CLK2,ACSL5,FGF9,HARS,MTIF2,TSN,GMFB,SUMO3,PSMG1,MARCH6,ST3GAL5,EIF3H,PAF1,DDX50,TASP1,SERINC1,SVIL,IGBP1,TROVE2 |
| 1.243e-02 | -4.39 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP | 186 | 35 | 17758 | 2279 |
SARS,EIF3C,PAPD4,WDR74,APRT,SPATS2L,NUP43,PHGDH,SBDS,ESAM,ASNS,PSMG4,SHMT2,PCOLCE2,YARS,C18orf21,HMBOX1,GARS,MPP6,WDR61,NARS,TBRG4,ZSCAN2,ABCF1,WARS,ZFAND3,SLC7A1,PWP1,RARS,ZNF622,MTHFD2,INSIG1,TBPL1,SQLE,PURB |
| 1.243e-02 | -4.39 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP | 186 | 35 | 17758 | 2279 |
USP7,BANP,MYCBP2,MCM6,MVK,CLK1,LAGE3,SF3A3,BCOR,RNASEH2B,ETFB,MPHOSPH10,THADA,FMNL1,MCM5,TIMELESS,WDR60,SLC27A5,TOP1,CCDC57,TRAPPC9,RAP1GAP2,POU2F1,ARHGAP32,IMPDH2,ZNF467,POLG2,ABCF1,CHAF1A,PWP1,CAT,APBB3,HSPBAP1,CNDP2,RNF114 |
| 1.243e-02 | -4.39 | SANT | prosite domains | PS51293 | 26 | 8 | 11866 | 1504 |
DNAJC2,NCOR2,SMARCC1,TRERF1,DNAJC1,NCOR1,CRAMP1,RERE |
| 1.243e-02 | -4.39 | GTF2A2 (general transcription factor IIA 2) | protein interactions | 2958 | 11 | 5 | 16036 | 2270 |
GTF2A1,POLR2A,TAF4,TERF2,TBPL1 |
| 1.243e-02 | -4.39 | VPS50 (VPS50 EARP/GARPII complex subunit) | protein interactions | 55610 | 11 | 5 | 16036 | 2270 |
VPS52,AMBRA1,VPS53,TSSC1,DTNBP1 |
| 1.243e-02 | -4.39 | FAM131C (family with sequence similarity 131, member C) | protein interactions | 348487 | 11 | 5 | 16036 | 2270 |
DNAJA3,MYC,SFI1,VSNL1,MAD1L1 |
| 1.243e-02 | -4.39 | TRAK1 (trafficking protein, kinesin binding 1) | protein interactions | 22906 | 11 | 5 | 16036 | 2270 |
KIF5C,SKIL,CDK6,POLR2A,TRAK1 |
| 1.243e-02 | -4.39 | BRD1 (bromodomain containing 1) | protein interactions | 23774 | 11 | 5 | 16036 | 2270 |
VIM,FEZ2,CEP126,ZNF512B,H2AFX |
| 1.243e-02 | -4.39 | C1orf111 (chromosome 1 open reading frame 111) | protein interactions | 284680 | 11 | 5 | 16036 | 2270 |
HLCS,CSNK1A1,MGLL,SNX24,CCDC85B |
| 1.252e-02 | -4.38 | HALLMARK_XENOBIOTIC_METABOLISM | MSigDB lists | HALLMARK_XENOBIOTIC_METABOLISM | 199 | 37 | 17758 | 2279 |
JUP,PDK4,HES6,ID2,TGFB2,ABHD6,MAN1A1,ADH5,GART,ENTPD5,LPIN2,SHMT2,HRG,LONP1,MTHFD1,GCNT2,UPP1,AP4B1,ABCC2,MARCH6,SLC35D1,ECH1,PYCR1,PGD,CAT,DDAH2,HPRT1,RETSAT,ETFDH,DCXR,ACOX1,PEMT,TNFRSF1A,ACP1,ABCC3,CNDP2,PDLIM5 |
| 1.256e-02 | -4.38 | retinoid X receptor binding | molecular function | GO:0046965 | 16 | 6 | 16491 | 2164 |
VDR,NSD1,FUS,NCOR1,NRIP1,PPARG |
| 1.256e-02 | -4.38 | poly-pyrimidine tract binding | molecular function | GO:0008187 | 16 | 6 | 16491 | 2164 |
ATXN1,MSI2,PABPC1,KHDRBS1,PABPC4,DIS3L2 |
| 1.256e-02 | -4.38 | poly-purine tract binding | molecular function | GO:0070717 | 16 | 6 | 16491 | 2164 |
DDX3X,ATXN1,SYNCRIP,PABPC1,KHDRBS1,PABPC4 |
| 1.257e-02 | -4.38 | sulfur amino acid metabolic process | biological process | GO:0000096 | 46 | 12 | 16441 | 2138 |
GGT1,MSRA,MRI1,DPEP1,AHCYL1,CNDP2,MTHFD2L,MTR,MPST,AHCYL2,PCYOX1L,MTHFD1 |
| 1.257e-02 | -4.38 | regulation of actin filament-based movement | biological process | GO:1903115 | 46 | 12 | 16441 | 2138 |
TNNC1,CAMK2D,DSC2,JUP,SCN1B,ANK2,DSG2,PDE4B,RYR2,CAV1,KCNH2,DSP |
| 1.257e-02 | -4.38 | RIBONUCLEOPROTEIN_BINDING | MSigDB lists | RIBONUCLEOPROTEIN_BINDING | 12 | 5 | 17758 | 2279 |
ETF1,EIF2A,PRPF31,MTIF2,TIMM50 |
| 1.257e-02 | -4.38 | MODULE_272 | MSigDB lists | MODULE_272 | 12 | 5 | 17758 | 2279 |
UMPS,MTHFD2,ODC1,MTHFD1,PYCR1 |
| 1.257e-02 | -4.38 | TRANSCRIPTION_ELONGATION_REGULATOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_ELONGATION_REGULATOR_ACTIVITY | 12 | 5 | 17758 | 2279 |
ELL,SUPT4H1,IKBKAP,SUPT5H,ELP3 |
| 1.257e-02 | -4.38 | ISOPRENOID_METABOLIC_PROCESS | MSigDB lists | ISOPRENOID_METABOLIC_PROCESS | 12 | 5 | 17758 | 2279 |
RETSAT,IDI1,MVK,PDSS2,RDH11 |
| 1.258e-02 | -4.38 | ubiquitin-like protein ligase binding | molecular function | GO:0044389 | 259 | 47 | 16491 | 2164 |
HERC2,USP7,CUL7,CUL4A,HM13,SCAMP3,PRDX6,FOXO1,ACTG1,STX8,UBXN1,NKD2,SMAD7,RIPK1,HSPA1A,AMBRA1,SKI,RNF40,CCDC50,TANK,FHIT,VCL,CASP10,PRKACB,ZNF675,KCNQ3,HSPA5,RANGAP1,BRCA1,KCNH2,UBE2K,TRIM37,POLR2A,HSPA1B,MFN2,SPOP,SMAD3,TRIB3,RAD18,HIF1A,PER1,CUL2,RRAGA,TRAF3,CLU,PRKAR2A,MID1 |
| 1.260e-02 | -4.37 | cytoskeletal part | cellular component | GO:0044430 | 1403 | 206 | 17570 | 2233 |
PTP4A1,POLB,CGN,CUL7,ACTG1,KIF5A,MKS1,TUBE1,ENAH,CSPP1,SIRT2,RAC3,BIRC2,SKI,DST,SRPRB,NEK6,RASSF3,NCKIPSD,XRCC2,MYH3,MAD1L1,RELB,SUCLG2,FNIP2,RAN,CEP135,CDK6,SPAG6,PRKACB,CEP128,DBN1,ATF4,LIMA1,KATNAL1,EYA3,KIF15,CAMSAP2,EFHC1,BRCA1,SH3GL1,ARPC3,CCDC28B,KIF16B,GNAI1,RHOU,DDAH2,BRCA2,RAD18,CHD3,RLTPR,CCDC146,PQBP1,DNAH2,TPM1,TSEN2,NRP1,C2CD5,HERC2,DCTN3,TNNC1,TTN,IFT57,JUP,PAX2,DPF2,SMAD7,DNAH1,MTUS1,CEP164,NAV1,CEP290,CCDC124,ATP6V0D1,AKAP11,PEA15,KRT20,MYO10,IFT43,HAUS6,RAP1GAP2,KIAA0586,PTPN12,ATAT1,PSMA1,MAP7D1,EVI5,DNAH14,IRS1,DYNC1H1,SPAG9,BICD1,NME7,FSCN1,SDCCAG8,DNAH17,CCDC85B,SLC16A1,TBL1X,NCOR1,SH3PXD2A,BRSK2,PRKAR2A,RTTN,DNM3,ID1,RAB11FIP4,CYLD,MAP2K5,PCNT,BIRC6,PAFAH1B1,SLC2A1,ACTR3,MYO7A,OLA1,MYH9,TBCCD1,TUBB6,RADIL,PIBF1,PPP1R9A,HSPA1A,FLNB,RPGRIP1L,SBDS,BLOC1S2,VPS18,MYH15,RMDN3,CORO1A,CEP63,PXK,VCL,PRPF19,TUBA1A,KRT7,ARHGEF10,VIM,PNN,DSP,TTC28,UBR4,SERP1,IFT81,CDC16,IKZF4,DCXR,G6PD,DNAJA3,WDR73,IFT140,XRCC4,YEATS2,MID1,CEP170,PARD3,MAPT,KIZ,KLC4,PDE4B,MAP1S,KIF5C,ID2,CEP126,CSNK1A1,MBNL1,MAD2L2,SFI1,IQGAP2,TTLL11,TADA3,NEBL,DCTN4,RDX,DYNC2H1,FBXO31,AMOT,ACTR3B,NUDC,SPTAN1,PXN,CEP83,VPS37A,TTLL5,APEX1,CEP295,TPM4,FERMT2,CCDC113,RANGAP1,PTK2,PALLD,HSPA1B,YIF1A,KLHL22,WDR35,STX1A,BCAS3,FNTB,SVIL,USP20,ATM,MYOM2,IGBP1,KIF1B |
| 1.260e-02 | -4.37 | TRANSCRIPTION_COACTIVATOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_COACTIVATOR_ACTIVITY | 123 | 25 | 17758 | 2279 |
APEX1,PPARGC1B,MED27,SMARCD3,SMARCA4,MED16,NR2F1,DYRK1B,SUB1,SNW1,SRCAP,GTF2A1,SMARCC1,COPS5,TAF4,MKL2,TBPL1,PQBP1,ZEB1,NFKBIB,NRIP1,HCFC2,RFXAP,CARM1,MAML3 |
| 1.261e-02 | -4.37 | Armadillo | interpro domains | IPR000225 | 36 | 10 | 18293 | 2341 |
ARMC4,KPNA1,KPNA3,ARMC6,JUP,ARMC5,RAP1GDS1,ARMC3,SPAG6,TMCO6 |
| 1.264e-02 | -4.37 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP | 167 | 32 | 17758 | 2279 |
SH2D3A,PRKAB2,ATF7IP,WDR37,TIGD1,ZNF44,PRKD3,GTF2H1,CELF1,TSHZ1,SLC40A1,RANBP6,IFNGR2,RSBN1,SLC26A11,ATXN7,GPC2,KIDINS220,CHD3,KIAA0355,TAF4,ZNF160,RIOK3,TBL1X,TNFRSF10D,PREPL,SETD6,FAM118A,XPO6,MID1,DCAF5,N4BP2L2 |
| 1.265e-02 | -4.37 | PRMT6 (protein arginine methyltransferase 6) | protein interactions | 55170 | 112 | 25 | 16036 | 2270 |
HMGA2,NOSTRIN,TFCP2,WDFY3,GRHL3,ID2,SMG7,ENAH,LENG8,FOSL2,GSTCD,SERGEF,UBR4,FOXC1,PEX7,ZNF557,PYCRL,DNAJA3,ZNF436,DNAJC12,ASB3,FBL,FIP1L1,PABPC1,N4BP2L2 |
| 1.266e-02 | -4.37 | nuclear replisome | cellular component | GO:0043601 | 26 | 8 | 17570 | 2233 |
BCAS2,POLE2,POLA1,PLRG1,PURB,POLE3,RPA1,PRPF19 |
| 1.270e-02 | -4.37 | regulation of sister chromatid segregation | biological process | GO:0033045 | 57 | 14 | 16441 | 2138 |
ANAPC1,KLHL22,CDC16,NSMCE2,ANAPC11,ANAPC10,TEX14,MAD1L1,CSNK2A1,ATM,HDAC8,MAD2L2,ANAPC4,UBE2E1 |
| 1.270e-02 | -4.37 | human chr16p11.2 | chromosome location | human chr16p11.2 | 127 | 21 | 26250 | 2590 |
KAT8,SEPHS2,SMG1P2,BCKDK,EIF3C,HSD3B7,DCTPP1,SRCAP,FBXL19-AS1,ARMC5,TMEM219,C16orf58,HIRIP3,FUS,CORO1A,ITGAX,FBXL19,XPO6,ZNF646,TNRC6A,ZNF629 |
| 1.271e-02 | -4.37 | SF3B6 (splicing factor 3b subunit 6) | protein interactions | 51639 | 63 | 16 | 16036 | 2270 |
SART1,CUL7,FN1,UTP14A,TRA2A,WDR18,ZC3H18,SON,PHF5A,BCAS2,ZNF326,RAN,FTSJ3,AGO3,PRPF19,TOP1 |
| 1.271e-02 | -4.37 | MARS (methionyl-tRNA synthetase) | protein interactions | 4141 | 63 | 16 | 16036 | 2270 |
GARS,CUL7,FN1,HARS,VARS,EEA1,CIAPIN1,OXSR1,EPRS,RARS,MYC,CDK9,HK2,XPNPEP1,EIF2S1,RNF2 |
| 1.272e-02 | -4.36 | ZC3H12A (zinc finger CCCH-type containing 12A) | protein interactions | 80149 | 15 | 6 | 16036 | 2270 |
SMAD3,USP10,ZC3H12A,UBC,TANK,IRAK2 |
| 1.272e-02 | -4.36 | DDX31 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 31) | protein interactions | 64794 | 15 | 6 | 16036 | 2270 |
RNF2,NIFK,DKC1,DDX24,ZC3H3,SIRT7 |
| 1.272e-02 | -4.36 | HSP90AB4P (heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene) | protein interactions | 664618 | 15 | 6 | 16036 | 2270 |
LRRC28,CDK9,SMYD3,PRPS1,CDK4,AGO3 |
| 1.272e-02 | -4.36 | POLE4 (polymerase (DNA-directed), epsilon 4, accessory subunit) | protein interactions | 56655 | 15 | 6 | 16036 | 2270 |
POLE3,UBE3A,POLE2,NUP133,POLA1,YEATS2 |
| 1.273e-02 | -4.36 | carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | carcinosarcoma-malignant_mesodermal_mixed_tumour | 36 | 10 | 17775 | 2278 |
BRCA2,BRAF,NRAS,NF1,ATM,MLH1,BRCA1,MET,MAP2K4,SMARCB1 |
| 1.273e-02 | -4.36 | negative regulation of transforming growth factor beta receptor signaling pathway | biological process | GO:0030512 | 74 | 17 | 16441 | 2138 |
CHST11,PRDM16,HSPA5,SMAD7,TGFBR2,ONECUT2,UBC,SKI,SKIL,SMAD3,PMEPA1,UCHL5,LEMD3,GLG1,PEG10,CAV2,USP15 |
| 1.273e-02 | -4.36 | negative regulation of cellular response to transforming growth factor beta stimulus | biological process | GO:1903845 | 74 | 17 | 16441 | 2138 |
CHST11,PRDM16,HSPA5,SMAD7,TGFBR2,ONECUT2,UBC,SKI,SKIL,SMAD3,PMEPA1,UCHL5,LEMD3,GLG1,PEG10,CAV2,USP15 |
| 1.273e-02 | -4.36 | regulation of translational initiation | biological process | GO:0006446 | 74 | 17 | 16441 | 2138 |
ATF4,EIF3C,EIF3J,MTIF2,KHDRBS1,EIF4A2,AGO2,EIF5B,EIF3H,PAIP2,CTIF,DDX3X,EIF2S1,NCBP2,RPS6KB1,EIF2B3,RPS6KB2 |
| 1.275e-02 | -4.36 | PML (promyelocytic leukemia) | protein interactions | 5371 | 193 | 39 | 16036 | 2270 |
USP7,BANP,NCOR2,FOXO1,ATRX,CSNK2A1,SMARCA4,ATF7IP,TGFBR2,SKI,TERF2IP,UBE3A,MYC,RNF111,ZMYM2,CDK6,CASP8AP2,MYB,RFC4,RBCK1,PPARG,SUMO3,ATXN1,TCF7L2,ARIH2,SH3GL1,SMAD3,SKIL,RANBP2,EHMT2,CCNT1,HIPK2,E2F4,TBX3,H2AFX,NCOR1,RUNX1,MAP2K4,KAT6A |
| 1.276e-02 | -4.36 | pancreas-carcinoma-mixed_acinar-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-mixed_acinar-ductal_carcinoma | 21 | 7 | 17775 | 2278 |
ATM,BRCA2,BRAF,BRCA1,NRAS,MET,HERPUD1 |
| 1.276e-02 | -4.36 | mixed_acinar-ductal_carcinoma | COSMIC cancer mutations | mixed_acinar-ductal_carcinoma | 21 | 7 | 17775 | 2278 |
ATM,BRCA2,BRAF,BRCA1,NRAS,MET,HERPUD1 |
| 1.276e-02 | -4.36 | pancreas-carcinoma-mixed_acinar-neuroendocrine-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-mixed_acinar-neuroendocrine-ductal_carcinoma | 21 | 7 | 17775 | 2278 |
ATM,BRCA2,BRAF,BRCA1,NRAS,MET,HERPUD1 |
| 1.276e-02 | -4.36 | pancreas-carcinoma-mixed_acinar-neuroendocrine_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-mixed_acinar-neuroendocrine_carcinoma | 21 | 7 | 17775 | 2278 |
ATM,BRCA2,BRAF,BRCA1,NRAS,MET,HERPUD1 |
| 1.276e-02 | -4.36 | mixed_acinar-neuroendocrine-ductal_carcinoma | COSMIC cancer mutations | mixed_acinar-neuroendocrine-ductal_carcinoma | 21 | 7 | 17775 | 2278 |
ATM,BRCA2,BRAF,BRCA1,NRAS,MET,HERPUD1 |
| 1.276e-02 | -4.36 | mixed_acinar-neuroendocrine_carcinoma | COSMIC cancer mutations | mixed_acinar-neuroendocrine_carcinoma | 21 | 7 | 17775 | 2278 |
ATM,BRCA2,BRAF,BRCA1,NRAS,MET,HERPUD1 |
| 1.277e-02 | -4.36 | HIST1H1C (histone cluster 1, H1c) | protein interactions | 3006 | 79 | 19 | 16036 | 2270 |
CUL4A,AEBP2,WDR61,SEC24D,ATRX,PRKCA,CDC73,POLR2A,PHF6,DOT1L,PAF1,NSD1,COPS5,CUL2,CTR9,RNF2,FIP1L1,ZC3H3,TOP1 |
| 1.278e-02 | -4.36 | single-organism intracellular transport | biological process | GO:1902582 | 1200 | 182 | 16441 | 2138 |
IMMP2L,THOC5,PRKAB2,KIF5A,DDX19A,NBEAL1,NUP160,SEC16A,SRPRB,EXOC1,RPS16,SRSF2,PMAIP1,ATP5G2,CNIH3,ATG3,NCKIPSD,AP1M1,VPS52,RAN,TIMM50,CDC37,GDAP1,ANK2,ATOX1,AP4B1,COL4A3BP,CUX1,NOL6,AKAP12,ZDHHC14,FLVCR1,MPC1,STOML2,PEX1,KIF16B,TIMM44,RBSN,CTAGE5,VPS13D,SGSM2,FIS1,C2CD5,NMD3,CHMP4C,IFT57,STX8,SEC24D,VTA1,STXBP6,NKD2,PIK3R4,SMG7,XPO7,SSR4,CLINT1,TIMM10,RHBDD1,SPIRE1,PRKCE,VAPB,TNPO3,TOMM34,USE1,TIMM8B,RANBP6,TRAPPC9,MYO10,IFT43,XPO5,RYR2,TRAPPC6B,EVI5,CPT1A,BLOC1S4,HERPUD1,TCF7L2,ATP9B,SEC31A,VPS13C,SPAG9,KPNA1,BICD1,NME7,RPL28,NSF,HIF1A,SNAP23,SRP68,HK2,PEX13,NAPA,SRP14,TESC,SGSM3,COG5,CHMP2A,SNX27,RAB11FIP4,PAFAH1B1,RPS29,VTI1A,AP1B1,DENND3,STAM,EEA1,GBF1,RPAIN,BLOC1S2,VPS18,NUP133,ZDHHC6,DTNBP1,NBEA,BCAP29,CORO1A,CPSF3,AHCYL1,ZC3H3,IPO11,LYST,AUP1,SEC24A,TUBA1A,RAB7A,NUP214,ERC1,VPS53,RAB10,ATP5D,RANBP2,ARHGAP21,IFT81,KPNA3,TIMM17A,IFT140,NFASC,ANXA2,SMG1,PARD3,MAPT,HM13,SCAMP3,TRAK1,SLC25A12,MAP1S,KIF5C,GAS6,MON2,NOL3,OPA1,TGFB2,TMCO6,NEDD4,SLC25A20,PEX7,SEC24C,PMPCA,UPF2,DYNC2H1,FGF9,VPS37A,AP4S1,FGF2,WDFY3,PACS1,PDE2A,RHOT2,NOP58,UBC,RERE,MFN2,CACNB1,ZDHHC11,WDR35,STX18,VPS37B,NCBP2,XPO6,KIF1B,IPO4,DDIT3 |
| 1.281e-02 | -4.36 | ANTI_APOPTOSIS | MSigDB lists | ANTI_APOPTOSIS | 117 | 24 | 17758 | 2279 |
PEA15,BRAF,BIRC6,FOXO1,RTN4,MCL1,AKT1S1,NOL3,OPA1,SON,HSPA1A,ERC1,CIAPIN1,HSPA1B,SNCA,ANXA1,DDAH2,BRE,TRIAP1,TBX3,ANXA5,TNFRSF10D,AVEN,BAG1 |
| 1.283e-02 | -4.36 | nuclear transport | biological process | GO:0051169 | 242 | 44 | 16441 | 2138 |
THOC5,CAMK1,DDX19A,SMG7,XPO7,TGFB2,NUP160,RSRC1,RPAIN,TMCO6,ANKRD54,MLX,SRSF2,NSRP1,NUP133,NCKIPSD,TNPO3,UPF2,RAN,AHCYL1,CPSF3,ZC3H3,IPO11,FGF9,RANBP6,XPO5,NOL6,ATXN1,AKAP13,NUP214,LSG1,NOP58,TCF7L2,RERE,RANBP2,KPNA1,MYBBP1A,KPNA3,SET,NCBP2,XPO6,NMD3,SMG1,IPO4 |
| 1.285e-02 | -4.35 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | MSigDB lists | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | 36 | 10 | 17758 | 2279 |
ACSL5,ELOVL6,AGPAT4,LPIN2,GPAM,LCLAT1,LPCAT1,LPIN1,HSD17B12,SLC25A1 |
| 1.285e-02 | -4.35 | BIOCARTA_P53HYPOXIA_PATHWAY | MSigDB lists | BIOCARTA_P53HYPOXIA_PATHWAY | 21 | 7 | 17758 | 2279 |
ATM,NFKBIB,GADD45A,CSNK1A1,HIF1A,TAF1,RPA1 |
| 1.286e-02 | -4.35 | MAHAJAN_RESPONSE_TO_IL1A_DN | MSigDB lists | MAHAJAN_RESPONSE_TO_IL1A_DN | 75 | 17 | 17758 | 2279 |
LAMA4,IL11RA,FOXN3,SLC25A12,RNF24,SLC29A1,UBR5,ADH5,ARL6IP5,VCAN,ACOX1,ZEB1,GSTA4,ME1,SYNJ2,POLR1C,LPP |
| 1.286e-02 | -4.35 | GCAAAAA,MIR-129 | MSigDB lists | GCAAAAA,MIR-129 | 180 | 34 | 17758 | 2279 |
PTP4A1,EFNB2,PAX2,TRIO,MED13L,ZFP36L1,ZMAT2,PCDH7,MAN1A1,CHD7,ZNF608,JAG1,NEBL,KDM2A,GLYR1,ETV1,TSHZ1,LSM12,ZMYM5,MARCKSL1,RSBN1,PRDM1,C11orf65,PITPNB,SOX4,AGAP1,SYT1,DDX3X,PMEPA1,HIC2,RPS6KB1,RUNX1,DLX2,PDLIM5 |
| 1.290e-02 | -4.35 | SF3A3 (splicing factor 3a subunit 3) | protein interactions | 10946 | 101 | 23 | 16036 | 2270 |
FLNC,SART1,CUL7,FN1,PRPF31,TCF3,PLRG1,WDHD1,TOX4,POP1,PRPF40B,HNRNPR,MCM5,COPS3,HNRNPH3,COPS5,CCDC85B,RNF2,PRPF4,FUS,PRMT5,SF3A1,PRPF19 |
| 1.292e-02 | -4.35 | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | MSigDB lists | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | 657 | 104 | 17758 | 2279 |
NDUFA5,PRDX6,SUCLG1,ACTG1,C16orf45,NDUFB5,PPP2R2A,NECAP1,GRINA,GYG1,SEC16A,AARS,KDM1A,NDUFB3,RTN1,FARSA,IDI1,ASNS,LPIN2,CLCN6,VPS52,CORO1A,RAN,NDUFA6,PEG10,YARS,PTPRK,GARS,FAM127A,NARS,ITPA,PTPRM,ATOX1,LGALS1,VSNL1,GMFB,MARCKSL1,SUMO3,CAMSAP2,VIM,CLNS1A,GNAI1,ARPC3,CDC16,DCXR,ARL4A,COPS5,WDR7,PAM,SLC25A11,AP2S1,MAPT,BAG1,DCTN3,SARS,AUH,SCAMP3,CA11,PRSS3,HSD17B10,PRAF2,FAN1,ARFIP2,SLC25A12,MLH1,SSR4,XPO7,NDUFS7,TTC1,FKBP1A,SUB1,NDUFV1,MLX,VPS72,NISCH,NDRG4,ERI3,FBL,TOMM34,ATP6V0D1,AKAP11,APEX1,ANKMY2,SULT4A1,SMARCD3,RNH1,RABAC1,R3HDM2,PDE2A,EHBP1,TRIM37,NCDN,ECH1,UBC,DYNC1H1,NSF,STX1A,TRAP1,FDPS,RRAGA,PSAP,IGBP1,SRP14,CORO2B |
| 1.292e-02 | -4.35 | ribosome disassembly | biological process | GO:0032790 | 8 | 4 | 16441 | 2138 |
MRRF,MTIF2,GFM2,DENR |
| 1.292e-02 | -4.35 | nucleoside monophosphate catabolic process | biological process | GO:0009125 | 8 | 4 | 16441 | 2138 |
HPRT1,AMPD3,NT5M,NT5E |
| 1.292e-02 | -4.35 | purine nucleotide salvage | biological process | GO:0032261 | 8 | 4 | 16441 | 2138 |
APRT,HPRT1,AMPD3,ADK |
| 1.292e-02 | -4.35 | protoporphyrinogen IX biosynthetic process | biological process | GO:0006782 | 8 | 4 | 16441 | 2138 |
HMBS,ALAD,CPOX,UROD |
| 1.292e-02 | -4.35 | negative regulation of cell migration involved in sprouting angiogenesis | biological process | GO:0090051 | 8 | 4 | 16441 | 2138 |
DLL4,MAP2K5,MMRN2,KLF4 |
| 1.292e-02 | -4.35 | tRNA wobble uridine modification | biological process | GO:0002098 | 8 | 4 | 16441 | 2138 |
CTU2,TRMU,ELP3,ALKBH8 |
| 1.292e-02 | -4.35 | heart field specification | biological process | GO:0003128 | 8 | 4 | 16441 | 2138 |
SMARCD3,RBPJ,BMP4,MEF2C |
| 1.292e-02 | -4.35 | secondary heart field specification | biological process | GO:0003139 | 8 | 4 | 16441 | 2138 |
SMARCD3,RBPJ,BMP4,MEF2C |
| 1.292e-02 | -4.35 | peptidyl-lysine monomethylation | biological process | GO:0018026 | 8 | 4 | 16441 | 2138 |
SETD7,KMT2A,SETD6,EHMT1 |
| 1.292e-02 | -4.35 | snoRNA metabolic process | biological process | GO:0016074 | 8 | 4 | 16441 | 2138 |
EXOSC2,EXOSC4,FBL,DKC1 |
| 1.292e-02 | -4.35 | regulation of transforming growth factor beta2 production | biological process | GO:0032909 | 8 | 4 | 16441 | 2138 |
SMAD3,GATA6,TGFB2,HIF1A |
| 1.294e-02 | -4.35 | hydrolase activity, acting on ester bonds | molecular function | GO:0016788 | 719 | 115 | 16491 | 2164 |
PTP4A1,PRDX6,PTPRA,PPP2R2A,ISG20L2,POP5,NT5C3A,ARSJ,PTPRG,PUDP,SYNJ1,ABHD6,AARS,PDE3A,LPIN1,EDC3,RPP30,SLX4,LYPLAL1,ERI1,XRCC2,LPIN2,HIBCH,NT5C,CPSF3,PNPLA4,MGLL,OGG1,PPM1K,TIMM50,PTPRK,PTPRM,GPCPD1,EYA3,GDPD1,TSN,PLCXD2,PDE8B,ZC3H12A,EXO1,RBBP8,SSU72,ABHD3,RAD51B,DUSP19,ALKBH1,ACP1,PPP3CC,EME1,TSEN2,NOCT,PTPN14,LDAH,HMGA2,SSH2,DROSHA,LARS2,AGO2,FAN1,TATDN3,PDE4B,MAP1S,VARS,PLA2G12A,C11orf54,RNASEH2B,GDPD5,PARN,INPP1,PTPN2,APLF,PDE10A,ACOT11,EXOSC4,NLGN3,SYNJ2,PNPLA3,ERI3,NT5M,N4BP2,LYPLA2,NT5E,DIS3L2,PFKFB4,EXOSC2,PDE4A,APEX1,POLA1,PTPN12,APTX,EXOG,PPIP5K2,PDE2A,PLCB1,PDE3B,NAPEPLD,SMPDL3B,ZRANB3,DAGLA,POP1,TOE1,FAM135A,DAGLB,PLPPR2,PTRH2,AEN,PTPN4,DTD1,CNOT6,BPNT1,TATDN1,PGAM5,PTP4A2,MTMR1,PDE9A |
| 1.298e-02 | -4.34 | S1 | pfam domains | PF00575 | 8 | 4 | 16629 | 2165 |
EIF2S1,SRBD1,SUPT6H,PDCD11 |
| 1.298e-02 | -4.34 | tRNA-synt_2b | pfam domains | PF00587 | 8 | 4 | 16629 | 2165 |
EPRS,SARS,GARS,TARS |
| 1.298e-02 | -4.34 | Chorein_N | pfam domains | PF12624 | 8 | 4 | 16629 | 2165 |
VPS13D,ATG2B,VPS13C,VPS13B |
| 1.298e-02 | -4.34 | JUN (jun proto-oncogene) | protein interactions | 3725 | 217 | 43 | 16036 | 2270 |
NCOR2,SARS,EGR1,TAF1,CSNK2A1,NECAP1,FOSL2,CLINT1,NEDD4,SKI,ABL1,JAG1,MYC,IKBKB,NRIP1,ETV1,SNAPC5,HNRNPM,TOP1,ELOF1,ATF4,PPARG,SMARCD3,SUMO3,PACS1,BRCA1,CCNDBP1,KMT2C,UBC,BATF3,SMAD3,VDR,MYBBP1A,HIF1A,CHD3,COPS5,TAF4,NCOR1,RUNX1,TPM1,RABEP1,MAP2K4,DDIT3 |
| 1.298e-02 | -4.34 | GSE27786_CD8_TCELL_VS_NKCELL_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_UP | 193 | 36 | 17758 | 2279 |
GGT1,USP7,AUH,NKD2,MAB21L3,IP6K2,SLC6A8,PHGDH,FLNB,DENR,ZKSCAN1,GRIN2C,DHX33,TTC3,HIBCH,RPL22L1,SERBP1,MYB,PMS1,ZNF654,ANKMY2,TBRG4,MTHFD1L,MEN1,TTC28,ACOXL,SLC39A14,CHD3,INTS9,AEN,HEATR1,PUS1,POLR1C,FAM118A,SMG1,STK4 |
| 1.298e-02 | -4.34 | GSE29618_BCELL_VS_MDC_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DN | 193 | 36 | 17758 | 2279 |
ACTG1,PSTPIP2,ID2,RTN4,RCAN1,SPATS2L,BHLHE40,ST3GAL6,DDIT4,DST,FKBP1A,RTN1,S100A10,ASAP1,ATG3,ANXA5,CORO1A,NDUFA6,ITGAX,GNG5,PEA15,WDR61,RAB7A,LGALS1,VIM,IL6R,COTL1,CPT1A,BATF3,CAT,KLF4,SYNGR2,ANXA2,APAF1,RBPJ,RNF130 |
| 1.298e-02 | -4.34 | GSE17721_POLYIC_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDM_UP | 193 | 36 | 17758 | 2279 |
POLB,MCM6,INSIG2,HES6,ZFP36L1,INPP1,REEP5,BIRC2,AHCYL2,MAP2K3,FRRS1,RPS16,HR,METTL8,TSPAN14,PLEKHA2,MPP6,RREB1,KDM5B,ZC3H18,PSMG1,SEMA3F,ATXN7,HSDL2,SRRD,SPEN,LRRC40,CTAGE5,DNAJC12,HMBS,BRWD3,ECHDC1,KIF1B,TNRC6A,MEF2C,USP15 |
| 1.298e-02 | -4.34 | GSE2826_WT_VS_XID_BCELL_UP | MSigDB lists | GSE2826_WT_VS_XID_BCELL_UP | 193 | 36 | 17758 | 2279 |
C9orf78,PRPF38B,MVK,MIF4GD,CCDC53,FAM207A,PTPRA,AP1B1,ST3GAL6,SLC1A1,UBL5,PABPC4,MAN1A1,NVL,MCM5,CMPK1,PPA1,GDAP1,STAG1,AKAP8L,DDX41,MARCKSL1,SHISA5,GALK2,SLC50A1,ISG15,POLR3A,ATP5D,DYNC1H1,GNG2,GTF2A1,SLC25A19,PPP3CC,KLHDC4,MUTYH,GCSH |
| 1.298e-02 | -4.34 | LINSLEY_MIR16_TARGETS | MSigDB lists | LINSLEY_MIR16_TARGETS | 193 | 36 | 17758 | 2279 |
EGR1,FAM189B,TMEM109,COX10,HSPA1A,PIP4K2A,SFR1,ELL,DNAJB6,NCKIPSD,SLC39A7,SLC16A9,MGLL,CDK6,LYPLA2,CHD9,ANAPC13,ATG9A,PCMT1,RNH1,PACS1,ZNFX1,NAPEPLD,USP46,MFN2,HSPA1B,POLR3G,PAF1,TSR1,INTS5,H2AFX,RNF138,EIF2S1,NMD3,ANKS1A,USP15 |
| 1.299e-02 | -4.34 | BROWNE_HCMV_INFECTION_16HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_UP | 219 | 40 | 17758 | 2279 |
BRAF,MAP3K13,ARFIP2,NECAP1,HLTF,SLC6A8,FAM49A,ZNF37A,RNF40,PRKD3,RNF2,SAP30,PRPF19,DTNB,PCGF3,MPP6,AKAP8L,KLHL23,SETD2,POU2F1,KCNH2,SON,VAC14,MAT2A,SLC7A1,ETFDH,IREB2,ARL4A,ABHD3,ALKBH1,SLC16A1,FKBP5,TRAF3,RPS6KB1,PRPF4,DDX10,BLMH,C18orf25,RFXAP,SMG1 |
| 1.299e-02 | -4.34 | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 400 | 67 | 17758 | 2279 |
MFGE8,MYH9,PLOD1,ARSJ,PRKCA,ECM1,S100A10,ATG3,MMP14,LAMA4,SEC24A,SKAP2,COL5A2,LIMA1,WLS,ATOX1,CAV1,SERP1,ARPC3,DCBLD2,SMAD3,SLC39A14,VDR,TNFRSF1A,FTSJ1,PAM,ADAM9,SEMA3C,CLU,ANXA2,NRP1,AP2S1,LPP,FN1,SEC24D,SMAD7,PRAF2,GAS6,TGFBR2,MBNL1,REEP5,ANXA7,PTRF,ASAP1,ANXA5,GMDS,CAV2,ATP6V0D1,SLC25A1,NT5E,VOPP1,PEA15,BDNF,LAMC1,FGF2,RAP1B,TPM4,RABAC1,KLF6,NEU1,ANXA1,CAT,SPAG9,ALG5,SNAP23,VCAN,PDLIM5 |
| 1.301e-02 | -4.34 | human chr5q31.3 | chromosome location | human chr5q31.3 | 33 | 8 | 26250 | 2590 |
RELL2,HARS,LOC101926941,HARS2,VTRNA1-3,SRA1,ZMAT2,TMCO6 |
| 1.308e-02 | -4.34 | RRCCGTTA_UNKNOWN | MSigDB lists | RRCCGTTA_UNKNOWN | 81 | 18 | 17758 | 2279 |
KLHL24,ID1,NFIA,KIAA0586,ATF7IP,VIM,SON,UBR4,RBBP8,GART,HNRNPR,PVRL3,MYC,BANF1,STC2,AP1M1,TNPO3,ZEB1 |
| 1.311e-02 | -4.33 | V$USF_Q6 | MSigDB lists | V$USF_Q6 | 252 | 45 | 17758 | 2279 |
DCTN3,DYM,NFX1,CHAC1,GYG1,BMP6,MFHAS1,GIGYF2,NOP56,PRKCE,FAM192A,SLC38A5,ARMC6,ATG3,ATIC,GLYR1,ACAP3,DCTN4,NCKIPSD,SLC38A2,GTF2H1,JOSD1,IGF2BP1,KIAA0922,PRPS1,HNRNPM,PPP1R9B,NRAS,CPT1A,SLC23A2,DDX3X,GTF2A1,TOM1L2,PER1,POLR3E,VPS37B,HOXA3,MPV17,TRMT2A,SLC16A1,DLX2,PFDN2,EME1,KDM4C,NIT1 |
| 1.312e-02 | -4.33 | parietal_lobe | COSMIC cancer mutations | parietal_lobe | 58 | 14 | 17775 | 2278 |
BRAF,NRAS,NF1,ATRX,CLCN6,BMP4,BCOR,RNF130,MET,MEN1,KIAA1549,FGFR1,GNAI1,SMARCB1 |
| 1.317e-02 | -4.33 | UBXN1 (UBX domain protein 1) | protein interactions | 51035 | 118 | 26 | 16036 | 2270 |
BTBD2,ATP6V1A,PAFAH1B1,VTA1,CDK4,UBXN1,HSPA5,HOMER2,BTBD9,BRCA1,UBR5,UBR4,UBC,CLNS1A,S100A16,DENR,RPA1,TTC1,KLHL22,UBE3A,HIF1A,UBR1,CUL2,AHCYL1,IGBP1,PRPF19 |
| 1.318e-02 | -4.33 | SANT_dom | interpro domains | IPR017884 | 26 | 8 | 18293 | 2341 |
DNAJC2,NCOR2,SMARCC1,TRERF1,DNAJC1,NCOR1,CRAMP1,RERE |
| 1.318e-02 | -4.33 | YTHDF1 (YTH N(6)-methyladenosine RNA binding protein 1) | protein interactions | 54915 | 33 | 10 | 16036 | 2270 |
PLPPR2,MFGE8,AGO2,IRAK2,SLC25A11,RNF2,SERPINH1,LRSAM1,BMI1,RPA1 |
| 1.318e-02 | -4.33 | PIK3C3 (phosphatidylinositol 3-kinase, catalytic subunit type 3) | protein interactions | 5289 | 33 | 10 | 16036 | 2270 |
DBN1,HSPA5,PIK3R4,MYH9,RNF2,PRMT5,USP11,KIF1B,HSPA1A,AMBRA1 |
| 1.318e-02 | -4.33 | ORC4 (origin recognition complex subunit 4) | protein interactions | 5000 | 33 | 10 | 16036 | 2270 |
FBXL5,MCM6,MCM10,KPNA1,ORC5,DBF4,MLH1,MCM2,PABPC1,MTUS1 |
| 1.318e-02 | -4.33 | BAZ1B (bromodomain adjacent to zinc finger domain 1B) | protein interactions | 9031 | 33 | 10 | 16036 | 2270 |
VDR,BAZ1A,ATAD5,CUL7,MYBBP1A,SMARCC1,SIRT7,SMARCA4,RNF2,SRRM2 |
| 1.318e-02 | -4.33 | ANXA6 (annexin A6) | protein interactions | 309 | 33 | 10 | 16036 | 2270 |
HPRT1,SIRT7,H2AFX,MLH1,POLE3,PRKCA,TXN2,CDC73,NAMPT,SNCA |
| 1.319e-02 | -4.33 | multi-organism cellular process | biological process | GO:0044764 | 698 | 111 | 16441 | 2138 |
USP7,CHMP2A,THOC5,CUL7,RAB11FIP4,CUL4A,UBN1,MFGE8,RPS29,NUP43,AP1B1,NUP160,GBF1,HSPA1A,SMARCB1,VPS18,RPS16,SHC1,NUP133,PPID,AP1M1,RAN,HCFC2,SEH1L,CARM1,RBCK1,BRD4,KRT7,RNMT,RAB7A,NFIA,TCEB3,VIM,CAV1,NUP214,UBR4,CXADR,CDHR3,TAF9B,DDX3X,TAF2,SMAD3,RANBP2,SUPT4H1,KPNA3,CCNT1,LSM14A,HIPK2,ITGA2,ATG7,TNFRSF1A,H2AFX,DPP4,SCARB1,COPS6,XRCC4,AP2S1,CHMP4C,EFNB2,TAF1,SUPT6H,ANKRD17,VTA1,NFX1,ATF7IP,GAS6,TRIM22,PSMF1,POM121,NEDD4,ELL,SNW1,UBE3A,TAF3,BANF1,GTF2H1,VAPB,LRSAM1,CAV2,TOP1,GTF2H3,VPS37A,POLA1,EIF4A2,LIG4,PSMA1,PACS1,SUPT5H,NELFA,VAC14,UBC,ISG15,POLR2A,HSPA1B,SRCAP,BICD1,KPNA1,SYNCRIP,GTF2A1,RPL28,CDK9,SPEN,VPS37B,SET,CUL2,TAF4,FDPS,RRAGA,NCBP2,TAF12,SLC52A2 |
| 1.327e-02 | -4.32 | WAKASUGI_HAVE_ZNF143_BINDING_SITES | MSigDB lists | WAKASUGI_HAVE_ZNF143_BINDING_SITES | 58 | 14 | 17758 | 2279 |
EXO1,POLB,PMS1,APEX1,RAD18,XPC,POLK,MSH3,FANCD2,LIG4,BRCA1,MSH4,APTX,MUTYH |
| 1.328e-02 | -4.32 | response to redox state | biological process | GO:0051775 | 12 | 5 | 16441 | 2138 |
RYR2,ADH5,SIRT2,NPAS2,ARNTL |
| 1.328e-02 | -4.32 | purine nucleobase biosynthetic process | biological process | GO:0009113 | 12 | 5 | 16441 | 2138 |
APRT,HPRT1,GART,PPAT,PRPS1 |
| 1.328e-02 | -4.32 | positive regulation of meiotic nuclear division | biological process | GO:0045836 | 12 | 5 | 16441 | 2138 |
MSX2,MSX1,SIRT2,PLCB1,DMRT1 |
| 1.328e-02 | -4.32 | positive regulation of DNA-dependent DNA replication | biological process | GO:2000105 | 12 | 5 | 16441 | 2138 |
WIZ,BMP4,ATRX,BMP6,STOML2 |
| 1.328e-02 | -4.32 | V$CP2_02 | MSigDB lists | V$CP2_02 | 239 | 43 | 17758 | 2279 |
TNNC1,ARHGAP26,GNB3,PRPF38B,MINK1,TRERF1,KIF5A,PAX2,NHS,MAB21L3,RSF1,CORO6,NBEAL1,TGFBR2,DDIT4,PRKCH,RTN1,NRF1,NISCH,GLTP,ETV1,TLCD1,PPP1R9B,BDNF,FGF9,IL11RA,LSM12,GRHL3,KCNH2,ODC1,RAB10,NR2F1,DDAH2,DSC2,LMBR1L,ADNP,HIF1A,XPNPEP1,BMP4,BRWD3,ZNF532,RAB30,ATXN7L2 |
| 1.331e-02 | -4.32 | chr4q32 | MSigDB lists | chr4q32 | 31 | 9 | 17758 | 2279 |
ETFDH,SH3RF1,CBR4,FNIP2,PALLD,DDX60,DDX60L,SPOCK3,ANXA10 |
| 1.331e-02 | -4.32 | CHO_NR4A1_TARGETS | MSigDB lists | CHO_NR4A1_TARGETS | 31 | 9 | 17758 | 2279 |
ABL2,SLC3A2,ASNS,ATF4,HLCS,INSIG1,KDM5A,DDIT3,HERPUD1 |
| 1.331e-02 | -4.32 | PROTEIN_AMINO_ACID_AUTOPHOSPHORYLATION | MSigDB lists | PROTEIN_AMINO_ACID_AUTOPHOSPHORYLATION | 31 | 9 | 17758 | 2279 |
TTN,CAMKK2,TAF1,MAP3K13,MEX3B,MAP3K12,CDK12,SMG1,STK4 |
| 1.331e-02 | -4.32 | NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSPORT | MSigDB lists | NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_TRANSPORT | 31 | 9 | 17758 | 2279 |
NUP133,KHDRBS1,SMG7,NCBP2,UPF2,SLC29A1,NUP160,SMG1,SLC23A2 |
| 1.334e-02 | -4.32 | hydroxymethyl-, formyl- and related transferase activity | molecular function | GO:0016742 | 8 | 4 | 16491 | 2164 |
SHMT2,GART,ATIC,ALDH1L2 |
| 1.334e-02 | -4.32 | hyalurononglucosaminidase activity | molecular function | GO:0004415 | 8 | 4 | 16491 | 2164 |
HYAL1,HYAL3,CD44,CEMIP |
| 1.335e-02 | -4.32 | Mab-21 | pfam domains | PF03281 | 12 | 5 | 16629 | 2165 |
ITPRIPL1,MB21D2,ITPRIP,MIEF1,MAB21L3 |
| 1.335e-02 | -4.32 | JAB | pfam domains | PF01398 | 12 | 5 | 16629 | 2165 |
COPS6,BRCC3,STAMBP,COPS5,EIF3H |
| 1.338e-02 | -4.31 | RRM_dom | interpro domains | IPR000504 | 220 | 40 | 18293 | 2341 |
NIFK,RBM33,RBFOX2,PPARGC1B,IGF2BP2,PABPC1L,RBM19,ENOX1,SYNJ1,SAFB2,HNRNPA3,SCAF8,HNRNPLL,PABPC4,IGF2BP3,RBM20,SRSF2,CELF1,IGF2BP1,SYNJ2,LARP4B,CNOT4,PABPC1,HNRNPM,MSI2,PTBP2,SETD1B,PSPC1,TRA2A,NOL8,RBM28,SYNCRIP,HNRNPR,SPEN,HNRNPH3,TRMT2A,NCBP2,RBM26,FUS,TNRC6A |
| 1.340e-02 | -4.31 | AMINO_ACID_TRANSPORT | MSigDB lists | AMINO_ACID_TRANSPORT | 26 | 8 | 17758 | 2279 |
SLC3A2,SERINC1,ARL6IP5,PRAF2,SLC25A12,SLC1A1,SLC16A10,SLC43A1 |
| 1.340e-02 | -4.31 | ONE_CARBON_COMPOUND_METABOLIC_PROCESS | MSigDB lists | ONE_CARBON_COMPOUND_METABOLIC_PROCESS | 26 | 8 | 17758 | 2279 |
NSD1,ATRX,EHMT1,PCMT1,ATF7IP,PRMT5,CARM1,MPST |
| 1.340e-02 | -4.31 | XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | MSigDB lists | XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | 26 | 8 | 17758 | 2279 |
LSS,DNMBP,PXN,UPP1,CD44,ANGPTL4,PHLDA2,NAV3 |
| 1.340e-02 | -4.31 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | MSigDB lists | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | 26 | 8 | 17758 | 2279 |
POLR3D,POLR3E,POU2F1,POLR3B,POLR1C,SNAPC4,POLR3A,SNAPC5 |
| 1.342e-02 | -4.31 | cilium organization | biological process | GO:0044782 | 191 | 36 | 16441 | 2138 |
RTTN,IFT57,PCNT,CELSR3,MKS1,ZIC2,CEP126,PIBF1,DNAH1,RPGRIP1L,CEP164,CEP290,CCDC40,DYNC2H1,TTC17,ATP6V0D1,TTLL5,CEP83,IFT43,WDPCP,TMEM216,KIAA0586,CCDC113,ONECUT2,CCDC28B,ARMC4,IFT81,TMEM237,NME7,WDR35,E2F4,ARL13B,BBIP1,IFT140,FNBP1L,LAMA5 |
| 1.345e-02 | -4.31 | GSE17721_CTRL_VS_LPS_2H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_2H_BMDM_UP | 187 | 35 | 17758 | 2279 |
TMEM183A,GRINA,LIAS,QSER1,TTI1,SEC16A,SCAF8,ANKRD54,SKI,NCKIPSD,TIMELESS,TSPAN14,PLEKHA2,TMEM14C,PRMT3,C12orf4,ELOF1,ACADS,PSMC3IP,HAUS6,ELP3,ATG12,TPRA1,TMEM186,TPK1,ZBTB25,PGD,MGAT2,VDR,COQ9,CRCP,PEX13,MED20,PTP4A2,BRCC3 |
| 1.345e-02 | -4.31 | MODULE_244 | MSigDB lists | MODULE_244 | 187 | 35 | 17758 | 2279 |
SEPHS2,CARS,MCM6,AK2,CAMK1,CSNK2A1,VARS,HLTF,MLH1,ABL2,MED24,CMPK1,CDK6,TRIP13,CLK2,SRPK2,MTHFD1,PFKFB4,PMS1,RFC4,RFC3,PRIM2,HARS,NARS,CDK4,POLA1,LIG4,MAT2A,TIMM44,PEX1,HELZ,POLE2,TRAP1,DDX10,NOLC1 |
| 1.345e-02 | -4.31 | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | 187 | 35 | 17758 | 2279 |
POLB,ZNF516,PRDX6,SLC48A1,TRAK1,COBLL1,OPA1,ABHD6,AARS,FLNB,SH2B3,YLPM1,NBEA,CTR9,RDX,SSBP1,MPST,MTHFD1,TBC1D8,FADS1,LRRC20,TIMM8B,ZNF124,RAB7A,SMARCD3,ALG5,BAZ2B,ARL4A,FAT1,SIL1,KIAA0196,MED20,NRP1,SMYD3,HS2ST1 |
| 1.345e-02 | -4.31 | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | 187 | 35 | 17758 | 2279 |
C17orf80,NDUFAF2,MED18,PDCD5,PABPC4,MRPS30,DCTPP1,HVCN1,NEK6,ATIC,SHMT2,LRP3,RABEPK,GTF2H3,ELP3,TMEM216,WBSCR22,SLC35F2,EXOG,CYB5B,VAC14,C1orf174,STOML2,CXADR,SLC7A1,TPD52L2,ALG5,SUPT4H1,FDPS,SLC25A19,SENP3,DTD1,SLC25A26,PDSS2,NR2C2AP |
| 1.345e-02 | -4.31 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 187 | 35 | 17758 | 2279 |
SLC12A7,PTCD2,AK2,GPBP1L1,PLA2G12A,CHN1,PRKCH,RPS16,NUP133,ATIC,TRIAP1,MYH3,ANP32B,RAN,ALDH18A1,FXN,SEH1L,IL11RA,RNMT,PARP2,R3HDM1,SLC35D1,PDE3B,MAT2A,RAD54B,RPA1,FBXO21,GRIK4,RARS,ZNF266,LSM14A,HERC1,POLR3E,PPP3CC,EIF2B3 |
| 1.345e-02 | -4.31 | GSE27786_CD8_TCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_NKTCELL_UP | 187 | 35 | 17758 | 2279 |
SNX27,NOSTRIN,ASH1L,ABCA3,HM13,APRT,NUP43,TGFBR2,CLINT1,RRN3,CTNNBL1,MBD2,DCTN4,PPCDC,CEP135,AVEN,GATAD2B,TMC7,USE1,IFRD1,PDK1,MON1A,SETD2,SLC35G1,USP10,MRRF,MEX3B,MEN1,PLCXD2,TMEM186,CCDC28B,PES1,NME7,STX1A,RLTPR |
| 1.345e-02 | -4.31 | GSE27786_BCELL_VS_NKCELL_UP | MSigDB lists | GSE27786_BCELL_VS_NKCELL_UP | 187 | 35 | 17758 | 2279 |
IMMP2L,JMJD6,PLA2G12A,COX10,UBTD2,MGA,ACD,RABGAP1L,ZEB1,SHMT2,CHD2,ETV1,FXN,POLR1E,LONP1,TIMM50,ZNF124,SETD2,FRA10AC1,TBRG4,MEN1,CLNS1A,CCDC150,PHF6,RDH11,YTHDF2,ADNP,POLR3E,HIC2,IFT140,BMP4,ADK,ZBTB11,IPO4,PKIB |
| 1.345e-02 | -4.31 | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN | 187 | 35 | 17758 | 2279 |
ZNF292,PCNT,RCHY1,C14orf159,PBX1,ZFP36L1,LCLAT1,PHLDA2,SBDS,ABL2,GART,ABCA5,NISCH,VGF,RELB,CORO1A,ERRFI1,NRIP1,TRMT12,C15orf41,FBXO17,GNL3,NPM3,SRA1,ST3GAL5,UBC,NCDN,ARIH2,GRIK4,GADD45A,HSPBAP1,ARNTL,TBX3,PSAP,MID1 |
| 1.345e-02 | -4.31 | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_UP | 187 | 35 | 17758 | 2279 |
FOXO1,TRIO,DLGAP4,ST3GAL6,FAM49A,PRKCH,FAM50A,NRIP1,FMNL2,TRIM14,TBC1D8,MSI2,PEA15,FBXW4,DNMBP,KDM5B,TXLNG,ZFYVE1,CRIM1,ARRDC3,TCEB3,CUX1,MEF2D,IL6R,PEAK1,MBNL2,ACOXL,HSD3B7,RERE,BTBD11,DCXR,BCAS3,IFT140,BAG1,PKIB |
| 1.346e-02 | -4.31 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | molecular function | GO:0016796 | 46 | 12 | 16491 | 2164 |
EXO1,TOE1,EXOSC2,APEX1,ERI1,CNOT6,APTX,EXOSC4,ERI3,NOCT,PARN,DIS3L2 |
| 1.349e-02 | -4.31 | GABRIELY_MIR21_TARGETS | MSigDB lists | GABRIELY_MIR21_TARGETS | 279 | 49 | 17758 | 2279 |
KLHL24,ZNF292,USP7,MYCBP2,TAF1,ATRX,PRKAB2,ST6GAL1,DDR2,PBX1,COBLL1,ENAH,RSF1,TGFB2,TGFBR2,UBR5,PAG1,MGA,LPIN1,RSPRY1,LONRF2,ZNF326,NBEA,IPP,PRICKLE2,POLR3B,ZMYM2,SRPK2,SCAF11,COL5A2,FOXN3,FERMT2,PHACTR2,ARHGEF12,PALLD,LYRM7,FBXL5,DDX3X,ARHGAP21,SAMD5,IREB2,GTF2A1,ADNP,PURB,APAF1,GPAM,TPM1,VASH2,ZNF532 |
| 1.349e-02 | -4.31 | primary neural tube formation | biological process | GO:0014020 | 92 | 20 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,LUZP1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SKI,HIF1A,BMP4,APAF1,PRKACB,MTHFD1 |
| 1.349e-02 | -4.31 | DNA-templated transcription, termination | biological process | GO:0006353 | 92 | 20 | 16441 | 2138 |
GTF2H3,POLR1A,MED18,POLR3A,POLR3G,UBTF,POLR3D,SRSF2,PTRF,POLR3E,CRCP,GTF2H1,NCBP2,POLR3B,POLR1B,POLR1C,CPSF3,ZNRD1,POLR1E,LSM10 |
| 1.350e-02 | -4.31 | gag (Pr55(Gag)) | protein interactions | 155030 | 895 | 150 | 16036 | 2270 |
PRDX6,ACTG1,DCP1B,NAT10,CSNK2A1,PRKCA,PABPC4,SMARCB1,TOM1L1,SRPRB,RAP1A,UBAP2L,AP1M1,RAN,PRKACB,TMPO,DBN1,SNU13,SLC3A2,PPARG,HSPA5,CAV1,ST3GAL5,GEMIN5,DDX3X,AHNAK,CCNT1,SH3RF1,TNFRSF1A,FIP1L1,CHMP4C,STX8,DROSHA,TRIM15,RLF,TGFBR2,ETFB,IGF2BP3,TOX4,PRKCE,MYC,BANF1,TNPO3,IGF2BP1,ALDH18A1,LRSAM1,PRF1,ATP6V0D1,PABPC1,DDX28,RAPGEF4,EIF4A2,RAP1B,RNH1,ISG15,DYNC1H1,EPRS,UBAP2,MYBBP1A,KPNA1,SYNCRIP,NSF,SRP68,SDCCAG8,RRAGA,IFITM2,DHCR7,DDX10,SRP14,PRKAR2A,CPT1C,SART1,CHMP2A,CYLD,AMOTL1,DNM3,LIN28B,OLA1,MYH9,PPP2R2A,HNRNPA3,HSPA1A,EEA1,FLNB,CAD,VPS18,SHC1,SOCS1,DNAJB6,ETF1,SERPINH1,ITGAX,VCL,ACSL5,NARS2,TUBA1A,MTIF2,RAB7A,VIM,RAB10,WARS,HLA-DMA,RANBP2,KPNA3,HNRNPR,COPS5,ZNF333,ATG7,SLC25A11,ANXA2,NOLC1,AP2S1,NIFK,AGO2,MAP1S,IGF2BP2,MON2,TRIM22,GIGYF2,NEDD4,PRKCH,DSG2,ANXA5,HARS2,RDX,DYNC2H1,CD44,AMOT,HNRNPM,RPS6KB2,SPTAN1,TOP1,PXN,VPS37A,LSM12,LDHA,PACS1,MARS,EIF5B,DDX49,TARS,UBC,HSPA1B,RARS,HNRNPH3,CUL2,VPS37B,EIF2S1,RBM26,KIF1B |
| 1.350e-02 | -4.30 | axoneme | cellular component | GO:0005930 | 88 | 19 | 17570 | 2233 |
IFT57,CFAP221,WDPCP,PIK3R4,EFHC1,DNAH1,RPGRIP1L,AMBRA1,ARMC4,WDR35,DNAH17,ARL13B,ATG7,IFT140,CCDC40,DNAH2,DYNC2H1,MAPT,SPAG6 |
| 1.350e-02 | -4.30 | ciliary cytoplasm | cellular component | GO:0097014 | 88 | 19 | 17570 | 2233 |
IFT57,CFAP221,WDPCP,PIK3R4,EFHC1,DNAH1,RPGRIP1L,AMBRA1,ARMC4,WDR35,DNAH17,ARL13B,ATG7,IFT140,CCDC40,DNAH2,DYNC2H1,MAPT,SPAG6 |
| 1.354e-02 | -4.30 | DNA_RECOMBINATION | MSigDB lists | DNA_RECOMBINATION | 47 | 12 | 17758 | 2279 |
EXO1,KPNA1,ATRX,SMARCAD1,TSN,RAD51B,ATM,BRCA1,MSH4,RPAIN,RAD54B,RPA1 |
| 1.354e-02 | -4.30 | LEONARD_HYPOXIA | MSigDB lists | LEONARD_HYPOXIA | 47 | 12 | 17758 | 2279 |
PLIN2,PFKFB4,PHC2,STC2,SLC2A1,HK2,JMJD6,BHLHE40,FOSL2,DDIT3,DDIT4,SAP30 |
| 1.354e-02 | -4.30 | PRDX1 (peroxiredoxin 1) | protein interactions | 5052 | 107 | 24 | 16036 | 2270 |
METTL1,SESN2,CUL7,CUL4A,FN1,PRDX6,RNH1,IKBKAP,ISG15,RPA1,SNCA,CAT,ADH5,ABL1,UBE3A,SHC1,FSCN1,UCHL5,MYC,COPS5,CUL2,FUS,COPS6,RPS6KB2 |
| 1.361e-02 | -4.30 | nucleoside triphosphate metabolic process | biological process | GO:0009141 | 204 | 38 | 16441 | 2138 |
NDUFA5,AK2,SUCLG1,ATP6V1A,NDUFB5,OLA1,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,DCTPP1,CAD,AMPD3,NDUFV1,ENTPD5,ATP5G2,MYH3,CMPK1,NDUFA6,FXN,PFKFB4,BDNF,ITPA,LDHA,ATP6V0A1,NUDT15,HSPA1B,SNCA,STOML2,ATP5D,NME7,COQ9,TBPL1,SURF1,HK2,NDUFS5,ADK |
| 1.362e-02 | -4.30 | V$PR_02 | MSigDB lists | V$PR_02 | 130 | 26 | 17758 | 2279 |
LAMA4,KRT20,BDNF,PXN,RWDD1,ZNF654,KHDRBS1,FRA10AC1,ATF7IP,PACS1,IP6K2,CA5B,NEDD4,NCDN,RERE,PHC2,SKIL,TECTA,DST,NSD1,EIF4ENIF1,SYNCRIP,ADNP,LUC7L3,DLX2,RAB30 |
| 1.364e-02 | -4.29 | KAT2B (K(lysine) acetyltransferase 2B) | protein interactions | 8850 | 182 | 37 | 16036 | 2270 |
NPAS2,POLR1A,TCF3,SMAD7,SIRT2,SMARCB1,TADA3,MYC,NRIP1,ETV1,PNMA1,CARM1,SERBP1,MYB,RPS6KB2,GATAD2B,ATF4,PDK1,CUX1,MEF2D,POLR2A,UBTF,SMAD3,SRCAP,BRCA2,TRRAP,EHMT2,CCNT1,HIF1A,HIPK2,ARNTL,BCAS3,H2AFX,RPS6KB1,TAF12,RBPJ,YEATS2 |
| 1.366e-02 | -4.29 | HOLLMANN_APOPTOSIS_VIA_CD40_DN | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_DN | 246 | 44 | 17758 | 2279 |
USP7,IFT57,TRIP6,PDE4B,ID2,TRIM22,BZW2,ABL1,ZNF239,DECR1,SUB1,BRE,VPS72,SUCLG2,ANXA5,GTF3C3,SERPINH1,UTS2,NAA35,PNMA1,FADS1,MSX1,TRIM13,ZNF124,ZNF195,TSTA3,STAMBP,ELOVL6,ANKMY2,CPOX,NXN,VIM,SATB2,C8orf33,ST3GAL5,TARS,MGAT2,OXSR1,PDLIM1,RNF138,BDH2,RWDD2B,ANXA2,CCNB1IP1 |
| 1.366e-02 | -4.29 | GTACTGT,MIR-101 | MSigDB lists | GTACTGT,MIR-101 | 246 | 44 | 17758 | 2279 |
ESCO1,FEM1C,ANKRD17,ATRX,C1orf52,BZW2,MBNL1,SLC1A1,POGZ,PLXNB1,DDIT4,SLC30A7,PRKCE,SH2B3,SUB1,ASAP1,CACNB2,ANKRD11,CDK6,TERF2,SRPK2,AEBP2,PDE4A,SYNGAP1,ADAMTSL3,CMIP,BAZ2A,SETD2,RAP1B,ATXN1,ARID1A,DCBLD2,DOT1L,GZF1,SPOP,ZFAND3,DDX3X,KIAA0355,PURB,GREB1L,MAGI1,SH3PXD2A,ZNF532,STK4 |
| 1.366e-02 | -4.29 | MAT2B (methionine adenosyltransferase II, beta) | protein interactions | 27430 | 38 | 11 | 16036 | 2270 |
P3H1,TUBA1A,KPNA3,TSTA3,G6PD,XPO5,ATG7,FERMT2,GMDS,MAT2A,GALE |
| 1.366e-02 | -4.29 | PAIP1 (poly(A) binding protein interacting protein 1) | protein interactions | 10605 | 38 | 11 | 16036 | 2270 |
SYNCRIP,TRA2A,H2AFX,ADSL,UPF2,PABPC1L,BMI1,UBR5,FTSJ3,PABPC1,PAIP2 |
| 1.366e-02 | -4.29 | ESRRA (estrogen-related receptor alpha) | protein interactions | 2101 | 38 | 11 | 16036 | 2270 |
ADH5,WDR36,NSD1,MAP2K5,ATXN1,SMARCD3,HDAC8,FUS,NRIP1,C2CD5,LYST |
| 1.366e-02 | -4.29 | TRIP12 (thyroid hormone receptor interactor 12) | protein interactions | 9320 | 38 | 11 | 16036 | 2270 |
USP7,CELSR3,CDK9,GNL3,MYC,SIRT7,ATF7IP,USP11,SOX6,UBC,RPA1 |
| 1.366e-02 | -4.29 | POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) | protein interactions | 55703 | 38 | 11 | 16036 | 2270 |
POLR3D,TSR1,POLR1A,POLR3E,CRCP,GPN1,POLR1B,POLR1C,POLR2A,POLR3A,POLR3G |
| 1.368e-02 | -4.29 | soft_tissue-striated_muscle-rhabdomyosarcoma | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma | 610 | 97 | 17775 | 2278 |
ARHGAP26,DMXL2,PHF3,PCNT,TRIM16,NF1,FANCD2,CACNA1H,PLOD1,BCOR,PTPRG,PABPC1L,SYNJ1,RADIL,SMARCB1,CHD7,JAG1,NUP133,NBEA,CCDC40,HIBCH,SRRM2,SEC24A,METTL1,NRAS,MIOS,SKIV2L2,CMIP,FAM111B,VIM,SATB2,AKAP13,ZDHHC14,DSP,SLC50A1,CHAF1A,BSN,ARMC4,CCDC3,MSRA,SLC30A3,ASTN2,ATG7,IFT140,ADAM9,SRFBP1,SMG1,ATXN7L2,MORC2,ZNF507,HERC2,IFT57,BRAF,ITFG1,MEX3A,ATF7IP,MLH1,RMI1,CDC73,BZW2,IQGAP2,FAM192A,COPS3,PMPCA,VAPB,PRICKLE2,ARHGAP1,ATP6V0D1,SOX6,FER1L5,ADAMTSL3,PRDM16,ZBED4,LDHA,RYR2,PRDM1,SYMPK,NR2F1,ZNF425,DYNC1H1,ASCC3,LRP1B,SPAG9,FAM135A,PMEPA1,HERC1,FAT1,DNAH17,ATM,RBPJ,MBD6,WDR33,TBCK,ZAK,MMP16,ZFHX2,CPT1C |
| 1.370e-02 | -4.29 | Fanconi anemia pathway | KEGG pathways | hsa03460 | 53 | 13 | 6908 | 881 |
BRCA2,SLX4,PALB2,POLK,FANCD2,TOP3A,FAN1,ATRIP,MLH1,BRCA1,EME1,RMI1,RPA1 |
| 1.370e-02 | -4.29 | Fanconi anemia pathway | KEGG pathways | ko03460 | 53 | 13 | 6908 | 881 |
BRCA2,SLX4,PALB2,POLK,FANCD2,TOP3A,FAN1,ATRIP,MLH1,BRCA1,EME1,RMI1,RPA1 |
| 1.374e-02 | -4.29 | humerus | COSMIC cancer mutations | humerus | 568 | 91 | 17775 | 2278 |
ARHGAP26,TRPM2,PHF3,PCNT,NAT10,ENAH,DDX60L,AHCYL2,PCDH7,JAG1,ABCA12,ZFHX3,RABGAP1L,SNTG2,ANKRD11,MRPS27,ME1,FHIT,PCOLCE2,ITGAX,VCL,FTSJ3,TBC1D8,KDM3B,LAMA4,GPM6A,EVL,COL5A2,PTPRM,ADAM32,METTL15,R3HDM1,PCNXL2,KSR2,MTHFD1L,LAMA2,SETD7,ZDHHC14,UBR4,TMEM132B,ARHGAP21,HYAL3,ELP2,ASTN2,LARGE,VPS13D,CSMD3,RUNX1,FUS,BEND6,RNF214,ZNF532,SMG1,RELL2,CSNK1A1,IQGAP2,ABCA7,TECTA,NEBL,UNC13A,LTN1,GREB1,LDLRAD3,GMDS,FMNL2,SNX29,HMGCR,USE1,TTLL5,PRIM2,DDX24,CRIM1,ELOVL6,RDH10,RYR2,ST6GALNAC3,MEN1,AGAP1,CYB5B,NAALADL2,ARMC3,CCDC150,POLR3G,CTIF,DYNC1H1,LRP1B,ZNF160,EXOC4,MBD6,ARHGAP10,MIPOL1 |
| 1.376e-02 | -4.29 | MACF1 (microtubule-actin crosslinking factor 1) | protein interactions | 23499 | 48 | 13 | 16036 | 2270 |
SKIL,USP7,EXOC1,TNIK,CUL7,FN1,TANGO6,SIRT7,DTNBP1,ATF7IP,CEP63,YBX3,TERF2 |
| 1.376e-02 | -4.29 | KPNA6 (karyopherin alpha 6 (importin alpha 7)) | protein interactions | 23633 | 48 | 13 | 16036 | 2270 |
TTC1,RANBP6,SURF2,KPNA3,RELB,BRCA1,RAN,EXOSC4,FBL,NOP58,PRKAR2A,SPOP,NOP56 |
| 1.376e-02 | -4.29 | SEC22B (SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)) | protein interactions | 9554 | 48 | 13 | 16036 | 2270 |
SART1,CUL7,FN1,STX1A,UBXN1,STX18,VAPB,SUCLG2,RNF2,SERPINH1,S100A16,MPST,RPA1 |
| 1.376e-02 | -4.29 | LPP (LIM domain containing preferred translocation partner in lipoma) | protein interactions | 4026 | 48 | 13 | 16036 | 2270 |
P3H1,UBE3A,SURF2,ALAD,COPS5,HSPA5,RDX,RANGAP1,RNF2,CPT1A,IPO11,CLNS1A,ARPC3 |
| 1.376e-02 | -4.29 | ORC2 (origin recognition complex subunit 2) | protein interactions | 4999 | 48 | 13 | 16036 | 2270 |
PES1,MCM6,MCM10,RAD18,MCM5,MYC,ORC5,DBF4,SIRT2,BRCA1,MCM2,TERF2,RPA1 |
| 1.376e-02 | -4.29 | HARS (histidyl-tRNA synthetase) | protein interactions | 3035 | 48 | 13 | 16036 | 2270 |
TTC1,SNW1,TNIK,SARS,C9orf78,GARS,G6PD,XPO5,ANXA5,DTD1,MARS,TARS,WARS |
| 1.376e-02 | -4.29 | CARD8 (caspase recruitment domain family, member 8) | protein interactions | 22900 | 48 | 13 | 16036 | 2270 |
FLNC,SRCAP,BRCA2,DPH1,WDR74,VPS72,ATXN2,ZNHIT6,NFRKB,BCOR,PEAK1,YEATS2,MGA |
| 1.376e-02 | -4.29 | SNRPA (small nuclear ribonucleoprotein polypeptide A) | protein interactions | 6626 | 85 | 20 | 16036 | 2270 |
CUL7,CUL4A,PTBP2,FN1,LIN28B,C19orf43,SF3A3,LENG8,UBC,ATIC,HNRNPH3,COPS5,CUL2,RNF2,AHCYL1,YARS,PABPC1,SF3A1,SRPK2,PRPF19 |
| 1.377e-02 | -4.28 | rRNA modification | biological process | GO:0000154 | 21 | 7 | 16441 | 2138 |
METTL15,METTL16,FBL,DKC1,FTSJ3,NOP58,NOP56 |
| 1.380e-02 | -4.28 | RNA polymerase I activity | molecular function | GO:0001054 | 12 | 5 | 16491 | 2164 |
POLR1B,POLR1C,ZNRD1,POLR1E,POLR1A |
| 1.380e-02 | -4.28 | mismatched DNA binding | molecular function | GO:0030983 | 12 | 5 | 16491 | 2164 |
PMS1,MSH4,MLH1,XPC,MSH3 |
| 1.380e-02 | -4.28 | PUJANA_BRCA2_PCC_NETWORK | MSigDB lists | PUJANA_BRCA2_PCC_NETWORK | 408 | 68 | 17758 | 2279 |
CSNK2A1,SMARCA4,HLTF,SSBP2,TTI1,PRKCA,UBR5,KDM1A,CAD,RPP30,BCAS2,HIRIP3,ZNF85,KIAA0922,TMPO,RFC4,RFC3,RBCK1,WDHD1,PNN,BRCA1,MCM2,TMEM186,MAT2A,EIF3H,CHAF1A,DCBLD2,PEX1,SLC7A1,HPRT1,RBBP8,BRCA2,TRRAP,INSIG1,H2AFX,PRPF4,MED20,RUNX1,BLMH,MUTYH,RFXAP,MCM6,TCF3,DBF4,MLH1,RNASEH2B,CLINT1,MFHAS1,ZNF354A,CEP290,MCM5,COPS3,TIMELESS,PRPS1,MYB,FDFT1,TOP1,FADS1,EXOSC2,POLA1,LIG4,CYB5B,RPA1,POLE2,ZNF330,FAT1,TAF4,ADK |
| 1.383e-02 | -4.28 | EDC4 (enhancer of mRNA decapping 4) | protein interactions | 23644 | 43 | 12 | 16036 | 2270 |
RFC4,DCP1B,SIRT7,SHMT2,EIF2B3,BMI1,ABCF1,FKBP3,GIT2,EDC3,RPA1,IGF2BP3 |
| 1.383e-02 | -4.28 | CDV3 (CDV3 homolog (mouse)) | protein interactions | 55573 | 43 | 12 | 16036 | 2270 |
CHMP2A,SNU13,TXLNG,NDUFAF2,LEMD3,IDH3G,UBAP2L,MRRF,FIS1,LARP4B,TIMM44,PGD |
| 1.383e-02 | -4.28 | SHMT1 (serine hydroxymethyltransferase 1 (soluble)) | protein interactions | 6470 | 43 | 12 | 16036 | 2270 |
CARS,DLEU1,TTC1,GARS,HARS,PPAT,ITPA,ATIC,XPO5,TSN,SHMT2,C18orf25 |
| 1.383e-02 | -4.28 | BMPR1A (bone morphogenetic protein receptor type IA) | protein interactions | 657 | 43 | 12 | 16036 | 2270 |
FKBP1A,MYC,SMAD7,CLDND1,CAV1,BMP4,PEG10,TGFBR2,BMP6,IGSF1,NEDD4,USP15 |
| 1.383e-02 | -4.28 | POSITIVE_REGULATION_OF_METABOLIC_PROCESS | MSigDB lists | POSITIVE_REGULATION_OF_METABOLIC_PROCESS | 233 | 42 | 17758 | 2279 |
EGR1,TRERF1,CDC42EP2,FOXO1,NPAS2,PPARGC1B,TCF3,ATF7IP,RSF1,FOXO3,BMP6,MAP2K3,PHF5A,PSMG4,GTF2H1,NRIP1,SAMD4A,MAML3,KAT8,TNK2,CAMKK2,ATF4,KDM5A,SMARCD3,BRCA1,ARID1A,SUPT5H,SMAD3,DYRK1B,HPRT1,NSD1,SUPT4H1,SMARCC1,HIF1A,MKL2,ARNTL,TNFRSF1A,ATG7,BMP4,RUNX1,MAPT,KAT6A |
| 1.383e-02 | -4.28 | V$NERF_Q2 | MSigDB lists | V$NERF_Q2 | 233 | 42 | 17758 | 2279 |
TCF12,SPRED2,MMRN2,ACTR3,VPS45,ST7L,BCOR,RSF1,GBF1,PCDH7,SLC30A7,JAG1,SLX4,UCHL5,IKBKB,CHD2,CORO1A,AGL,VCL,LYPLA2,HN1,PPP1R9B,IL11RA,ADAMTSL3,BAZ2A,NFIA,GMFB,FOXRED1,C1orf122,UBTF,SDCCAG8,CCDC85B,TRMT2A,BMP4,GGT7,NRP1,MID1,ZMAT3,TROVE2,DDIT3,LRRC41,SLC43A1 |
| 1.384e-02 | -4.28 | CAGCACT,MIR-512-3P | MSigDB lists | CAGCACT,MIR-512-3P | 149 | 29 | 17758 | 2279 |
PTBP2,FEM1C,ACTG1,FOXN3,ARHGEF10,ATXN1,PCNXL2,LPCAT3,RSBN1,MBNL2,MBNL1,USP46,MAT2A,ANKRD54,SPOP,ATXN7,UBAP1,LSM14A,DNAJA3,HIC2,PURB,SGSM2,PTPN4,JOSD1,ETV1,FNBP1L,MAP2K4,KAT6A,NIT1 |
| 1.390e-02 | -4.28 | CTGRYYYNATT_UNKNOWN | MSigDB lists | CTGRYYYNATT_UNKNOWN | 64 | 15 | 17758 | 2279 |
CCDC3,GNB3,PCNT,SREBF2,GADD45A,SOCS1,RREB1,CACNB2,TMEM109,GTF2IRD1,CSMD3,ERRFI1,SOX4,NCDN,DKK1 |
| 1.394e-02 | -4.27 | GSE27786_LIN_NEG_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NEUTROPHIL_UP | 181 | 34 | 17758 | 2279 |
RTTN,IMMP2L,SARS,DNAJA4,FOXO1,DDX19A,TMEM177,SPATS2L,PSMF1,RSRC1,MCM9,MFHAS1,METTL16,FARSA,CBR4,C16orf58,POLR1B,NT5M,LONP1,SLC25A1,ACSL5,CHD9,WBSCR22,SCFD2,PNN,SLC35D1,ANGPTL4,C1orf174,RARS,COQ9,ARNTL,CEBPZ,SRFBP1,TXN2 |
| 1.394e-02 | -4.27 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN | 181 | 34 | 17758 | 2279 |
RHOBTB1,GPR143,TMEM104,DPM3,SEMA6A,TTC1,DST,EIF2S2,S100A10,TNPO3,PNPLA4,MTHFD2L,VCL,RABEPK,ZNF629,TIMM8B,SFSWAP,EPS15L1,KCNMA1,ATAT1,HIST1H2BL,C10orf76,EIF5B,TCTN1,OSBPL1A,SERF2,DNAJC1,CCNT1,FAM206A,MPV17,ANXA2,IGBP1,TROVE2,LPP |
| 1.396e-02 | -4.27 | RAO_BOUND_BY_SALL4 | MSigDB lists | RAO_BOUND_BY_SALL4 | 220 | 40 | 17758 | 2279 |
INSIG2,FN1,PRDX6,ZNF280C,SMG7,ZFP36L1,SEC16A,UBR5,CHD7,ZNF608,ASNS,SLC38A2,ZNF148,CHD2,GTF3C3,LYRM5,CWF19L2,ETV1,SERBP1,SLC25A1,MBTPS2,GPM6A,AEBP2,GCNT2,TXLNG,UPP1,ARRDC3,AKAP12,ZDHHC14,FGFR1,DKK1,PLIN2,SLC39A14,SYNCRIP,FGFBP1,TP53BP1,SLCO5A1,NOLC1,ZNF532,LMBRD2 |
| 1.396e-02 | -4.27 | KONDO_EZH2_TARGETS | MSigDB lists | KONDO_EZH2_TARGETS | 220 | 40 | 17758 | 2279 |
COMMD10,ZNF76,NPAS2,CNTNAP3,TNFRSF21,VTI1A,ID2,NOL3,ST3GAL6,ANXA10,CCDC50,NEBL,HAS3,ABCA5,CNIH3,CFDP1,ZEB1,UTS2,MTHFD2L,MGLL,C6orf89,SAMD4A,CSGALNACT2,NT5E,DPF3,ANTXR2,WDR61,PRIM2,KCNMA1,TFPI,MEF2D,IL6R,AKAP13,MSX2,VPS13C,C2orf82,SCARB1,DLX2,NRP1,C18orf25 |
| 1.400e-02 | -4.27 | TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 422 | 70 | 17758 | 2279 |
POLB,MVK,PDK4,DDR2,CSNK2A1,RIPK1,MAP2K3,PRKD3,NEK6,PHKA1,POLE3,CMPK1,MET,PXK,FXN,PRKACB,SRPK2,TNK2,PDK1,COL4A3BP,GALK2,SGK2,DKC1,POLG2,STK10,FGFR1,NRP1,SMG1,XYLB,TNIK,BCKDK,TTN,MINK1,AK2,CLK1,MAP3K13,TAF1,TRIO,RPS6KA5,CSNK1A1,TGFBR2,PRKCH,PRKCE,PI4KB,PIGG,GTF2H1,MAP3K12,N4BP2,PRPS1,CLK2,RPS6KB2,SIK3,CAMKK2,PRIM2,CRIM1,POLA1,PIK3CB,POLR3G,OXSR1,POLE2,CDK9,IRAK2,HK2,ATM,POLR1C,ADK,BRSK2,RPS6KC1,ZAK,STK4 |
| 1.403e-02 | -4.27 | one-carbon metabolic process | biological process | GO:0006730 | 36 | 10 | 16441 | 2138 |
MTHFD2,ALDH1L2,SHMT2,MTHFD1L,CA5B,AHCYL1,MTHFD2L,MAT2A,AHCYL2,MTHFD1 |
| 1.403e-02 | -4.27 | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | 194 | 36 | 17758 | 2279 |
ARHGAP26,FAM208B,FEZ2,SESTD1,PPARGC1B,SPRYD7,C16orf45,SLC25A12,BIRC2,FLNB,SLC30A7,TOX4,TANK,PLEKHA2,SEH1L,VOPP1,CHD9,TXLNG,USP49,TLE3,USP42,RSBN1,GNL1,ZNF407,C8orf33,WARS,EXOC6,SKIL,RANBP2,RBBP8,APAF1,BRWD3,LRRC41,KAT6A,LRCH1,RNF114 |
| 1.403e-02 | -4.27 | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | 194 | 36 | 17758 | 2279 |
CHMP2A,FEZ2,ATP6V1A,ID2,RTN4,GYG1,CSTA,CSNK1A1,IQGAP2,S100A10,ATG3,PAK1IP1,TOP1,TIMM8B,PXN,LGALS1,C5AR1,ATXN1,RNH1,VIM,MAP7D1,IL6R,UBR4,TCF7L2,NEU1,WARS,TBC1D2,ANXA1,PGD,G6PD,VCAN,TNFRSF1A,SVIL,RNF130,PSAP,ANXA2 |
| 1.403e-02 | -4.27 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 194 | 36 | 17758 | 2279 |
SRM,ZNF292,TRIP6,C16orf45,PDE4B,MED13L,ARFIP2,RCAN1,FOSL2,RPS6KA5,BMP6,KDM2A,BCAS2,S100A10,SOCS1,SYN2,MCM5,MAP3K14,SERPINH1,TOMM34,SLC25A1,PDK1,PSMC3IP,TPM4,MARCKSL1,IMPDH2,MEN1,SLC35D1,MCM2,ANXA1,SLC39A14,GADD45A,VCAN,KLF4,ZZEF1,SLC43A1 |
| 1.403e-02 | -4.27 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | 194 | 36 | 17758 | 2279 |
SLC12A7,RTTN,WDR75,ASH1L,SUPT6H,TTC27,XPC,FAM189B,WDR13,H2AFJ,NECAP1,CCNL2,FAM8A1,SBDS,NEDD4,CD96,RPS16,SURF2,ZEB1,TTC3,POLR1B,PRMT3,PRKACB,EVL,PDK1,EPS15L1,ELP3,SHISA5,IL6R,RABAC1,POLR3A,RERE,TSR1,COQ9,ZFP90,DDIT3 |
| 1.413e-02 | -4.26 | ATP5O (ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit) | protein interactions | 539 | 69 | 17 | 16036 | 2270 |
HMBOX1,CUL7,TRIP6,TFIP11,RAB7A,ATP6V0A1,RTN4,UBC,ATP5D,ANXA7,RNF2,BCAP29,BRCC3,PNMA1,ATP6V0D1,MIPOL1,MTCH1 |
| 1.413e-02 | -4.26 | GTF3C1 (general transcription factor IIIC subunit 1) | protein interactions | 2975 | 69 | 17 | 16036 | 2270 |
SNU13,SMARCAD1,SIRT7,SUPT5H,PHGDH,KLF6,CHN1,SUB1,HNRNPR,MYC,RNF2,GTF3C3,FBL,BMI1,NOLC1,HNRNPM,TOP1 |
| 1.418e-02 | -4.26 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP | 118 | 24 | 17758 | 2279 |
BANP,IFRD1,DNAJA4,SLC3A2,SESN2,VPS37A,RBM33,C16orf52,RSL1D1,RNF24,JMJD6,RCAN1,HERPUD1,SPIRE1,CNST,PMAIP1,DNAJB6,HSPB8,RELB,PPP3CC,MTHFD2L,KIF1B,DDIT3,N4BP2L2 |
| 1.419e-02 | -4.25 | skeletal system morphogenesis | biological process | GO:0048705 | 211 | 39 | 16441 | 2138 |
CHST11,INSIG2,PPARGC1B,DDR2,BARX2,TGFB2,TGFBR2,NLE1,BMP6,SLC39A1,SKI,PEX7,MMP14,ANKRD11,HYAL1,ZEB1,SERPINH1,CARM1,MTHFD1,MSX1,ARID5B,SETD2,RDH10,SATB2,MEF2D,MTHFD1L,FLVCR1,FGFR1,SMAD3,MSX2,INSIG1,CSRNP1,HOXA3,GLG1,IFT140,BMP4,DLX2,MMP16,MEF2C |
| 1.421e-02 | -4.25 | PNPT1 (polyribonucleotide nucleotidyltransferase 1) | protein interactions | 87178 | 24 | 8 | 16036 | 2270 |
GATC,PDLIM1,PRKCSH,SIRT7,PMPCA,RANGAP1,NUP214,FAHD1 |
| 1.421e-02 | -4.25 | FAM208B (family with sequence similarity 208, member B) | protein interactions | 54906 | 24 | 8 | 16036 | 2270 |
FAM208B,NEK6,PRKAB2,SIRT7,CCDC85B,ATRIP,NFX1,POLR1C |
| 1.421e-02 | -4.25 | ADAP1 (ArfGAP with dual PH domains 1) | protein interactions | 11033 | 24 | 8 | 16036 | 2270 |
PRKCE,SUB1,SRSF2,GADD45A,SDCBP2,SF3A3,PRKCA,CSNK1A1 |
| 1.421e-02 | -4.25 | FAM175B (family with sequence similarity 175, member B) | protein interactions | 23172 | 24 | 8 | 16036 | 2270 |
USP7,BRE,SPAG9,LAMC1,BIRC6,BRCC3,UBC,AUP1 |
| 1.421e-02 | -4.25 | PELO (pelota homolog (Drosophila)) | protein interactions | 53918 | 24 | 8 | 16036 | 2270 |
TP53BP1,MYC,SMARCA4,SLC25A12,HEATR1,YBX3,NOP56,TIMM50 |
| 1.421e-02 | -4.25 | human chr4q12 | chromosome location | human chr4q12 | 40 | 9 | 26250 | 2590 |
EXOC1,DANCR,PPAT,ERVMER34-1,SRD5A3,SCFD2,CEP135,FIP1L1,USP46 |
| 1.424e-02 | -4.25 | cellular lipid catabolic process | biological process | GO:0044242 | 160 | 31 | 16441 | 2138 |
MCEE,ACADS,SESN2,PRDX6,RAB7A,PCCA,GPCPD1,SIRT2,ABHD6,CPT1A,NAPEPLD,ACOXL,MMAA,NEU1,LPIN1,SMPDL3B,ECH1,ETFB,DAGLA,DECR1,PEX7,ETFDH,ACOX1,SRD5A3,LPIN2,BDH2,PEX13,PNPLA3,MGLL,PRKACB,CPT1C |
| 1.429e-02 | -4.25 | heat shock protein binding | molecular function | GO:0031072 | 80 | 18 | 16491 | 2164 |
DNAJC2,DNAJA4,NPAS2,CSNK2A1,BCOR,DLST,HSPA1A,HSPA1B,SACS,HIF1A,PPID,DNAJA3,DNAJB6,ARNTL,FKBP5,APAF1,TOMM34,CDC37 |
| 1.432e-02 | -4.25 | HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1) | protein interactions | 3320 | 760 | 129 | 16036 | 2270 |
CUL4A,ACTG1,HECTD3,CSNK2A1,STK33,PRKCA,AARS,AMBRA1,RPS16,THAP4,RNF111,CDK6,PRKACB,CDC37,ZBTB17,TNK2,RBCK1,KLHL23,CDK4,HSPA5,KSR2,HDAC8,CAV1,BRCA1,KCNH2,SGK2,DYRK1B,TNFRSF1A,ASB3,COPS6,FN1,RHOBTB1,SSR4,TGFBR2,CDC73,RNF40,PRKCE,MCM5,MYC,COPS3,PPIL2,PRMT5,MAP3K12,LRSAM1,TOMM34,TERF2,MTHFD1,CAMKK2,ZBED4,PRDM1,METTL22,SUPT5H,TRIM37,ISG15,DYNC1H1,EPRS,HIF1A,CDK9,IRAK2,SENP3,CNOT6,SMYD3,AGO3,RNF114,MAP2K5,PAFAH1B1,NPAS2,DDR2,RIPK1,MYH9,HSPA1A,VPS18,SHC1,PPID,ARMC5,RPS6KL1,IKBKB,SOCS6,SSBP1,MET,PRPF19,PCGF3,TUBA1A,ENC1,EIF3H,FGFR1,SNCA,CAMK2D,DNAJA3,COPS5,ARNTL,CAMKMT,H2AFX,FKBP5,RPS6KB1,NFRKB,FUS,MID1,SMG1,TRIM36,BRAF,MINK1,AGO2,RCAN1,IP6K2,RPS6KA5,CSNK1A1,GIGYF2,ABL1,PRKCH,NPRL2,LARP4B,MAP3K14,RPS6KB2,SPTAN1,CLK2,NUDC,MARCH9,FBXO17,PSAT1,LDHA,PTK2,HSPA1B,MKX,KLHL22,CUL2,SVIL,APAF1,RPS6KC1 |
| 1.443e-02 | -4.24 | PPARG (peroxisome proliferator-activated receptor gamma) | protein interactions | 5468 | 136 | 29 | 16036 | 2270 |
USP7,NCOR2,MIF4GD,FOXO1,PPARG,JMJD1C,SMARCD3,SMARCA4,CAV1,PRKCA,SYT1,UBC,NEDD4,SMAD3,VDR,MSX2,NSD1,BCAS2,KLF4,JAZF1,COPS5,IKBKB,SVIL,MED24,NCOR1,SERPINH1,NFKBIB,NRIP1,KDM4C |
| 1.443e-02 | -4.24 | GSE10325_BCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_BCELL_VS_MYELOID_UP | 175 | 33 | 17758 | 2279 |
ADAM19,WDR74,ST6GAL1,TCF3,PDE4B,NFX1,ASNS,ATIC,SHMT2,NT5C,FBL,PRPS1,MICAL3,HTRA2,CTC1,PRKACB,PTPRK,FBXW4,EVL,SLC38A1,ARID5B,GNG7,BCS1L,MCM2,MEN1,ODC1,TCTN1,DSP,GLS,PDLIM1,POLR3E,LARGE,SYNPO |
| 1.444e-02 | -4.24 | response to catecholamine | biological process | GO:0071869 | 31 | 9 | 16441 | 2138 |
GNG2,ABL1,BDNF,ID1,EGR1,PDE4B,RYR2,SIRT2,SNCA |
| 1.444e-02 | -4.24 | termination of RNA polymerase I transcription | biological process | GO:0006363 | 31 | 9 | 16441 | 2138 |
UBTF,GTF2H3,PTRF,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 1.445e-02 | -4.24 | mRNA splice site selection | biological process | GO:0006376 | 26 | 8 | 16441 | 2138 |
PTBP2,LUC7L3,SF3A3,CELF1,PRPF39,NOL3,MBNL1,SF3A1 |
| 1.453e-02 | -4.23 | glial cell development | biological process | GO:0021782 | 75 | 17 | 16441 | 2138 |
KCNQ3,NF1,ARHGEF10,ID2,VIM,SIRT2,LAMA2,SOX4,PHGDH,TCF7L2,SKI,TSPAN2,CLU,MYRF,EIF2B3,CDK6,PARD3 |
| 1.455e-02 | -4.23 | REACTOME_HIV_INFECTION | MSigDB lists | REACTOME_HIV_INFECTION | 188 | 35 | 17758 | 2279 |
TAF1,NUP43,AP1B1,PSMF1,POM121,ELL,NUP133,BANF1,AP1M1,GTF2H1,RAN,SEH1L,GTF2H3,VPS37A,RNMT,TCEB3,PSMA1,LIG4,RANGAP1,PACS1,SUPT5H,NUP214,POLR2A,RANBP2,KPNA1,SUPT4H1,GTF2A1,CCNT1,CDK9,VPS37B,TAF4,NCBP2,TAF12,XRCC4,AP2S1 |
| 1.455e-02 | -4.23 | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | 188 | 35 | 17758 | 2279 |
FBXO45,PIGM,MCM10,SF3A3,C1orf52,XPO7,NAMPT,DCTPP1,NUBPL,ARMC5,DDX31,CDK6,PPA1,CDK12,NUDC,LAMC1,NARS,CDK4,GNL3,ZBED4,PCMT1,MARS,MTHFD1L,ANXA1,STOML2,OXSR1,HPRT1,COPS5,ARL4A,ADAT2,HNRNPH3,MDN1,TXN2,PDCD11,CEP170 |
| 1.455e-02 | -4.23 | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | 188 | 35 | 17758 | 2279 |
KCTD7,NDUFA5,EGR1,TTC27,ANKRD17,ITFG1,PARN,NLE1,BRE,ASNS,INTS7,ZNHIT6,TRIAP1,SHMT2,SSBP1,RAN,PRMT5,FBL,PNMA1,HSD17B12,NIPSNAP1,FAM127A,PCCA,ABCF2,C11orf49,SOX4,CLNS1A,RERE,STOML2,RPA1,SLC39A14,SMARCC1,SQLE,UMPS,COPS6 |
| 1.455e-02 | -4.23 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 188 | 35 | 17758 | 2279 |
DNM3,PSTPIP2,RPS29,OPHN1,NUP43,TRIM22,OPA1,TGFBR2,POGZ,ABCA7,SACS,PPID,IKBKB,RNF111,VAPB,CORO1A,AGL,AKAP11,PRKACB,LYST,CASP8AP2,PTPRK,NIPSNAP1,HMBOX1,RFC3,WDFY3,PSPC1,RAP1GDS1,BAZ1A,CAT,HLA-DMA,KIAA0355,SET,FNBP1L,KAT6A |
| 1.455e-02 | -4.23 | GSE17721_0.5H_VS_12H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_POLYIC_BMDM_UP | 188 | 35 | 17758 | 2279 |
MVK,AUH,FOXO1,DDX18,FAM189B,RARS2,SEC16A,PIP4K2A,PABPC4,SLC39A11,RAP1A,PHF5A,KDELC1,ANP32B,ALDH18A1,YARS,C6orf89,VPS37A,COL17A1,NOL6,USP10,KRTCAP2,SLC50A1,CHCHD6,CLNS1A,STOML2,PES1,LSM14A,ACOX1,HMBS,KLHDC4,ADK,ZNF532,AP2S1,SYNPO |
| 1.455e-02 | -4.23 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | 188 | 35 | 17758 | 2279 |
SPRED2,AK2,EGR1,HSD17B10,CSNK2A1,TMEM177,TUBB6,HDDC2,NDUFS7,MRPS11,DCTPP1,DSG2,KDELC1,PAK1IP1,TIMELESS,SHMT2,NT5C,PRF1,COQ3,TRIP13,MYB,TIMM8B,WARS2,DDX41,TSTA3,LGALS1,BRCA1,PALLD,PYCR1,SLC39A14,YIF1A,TRIB3,MTHFD2,POLE2,PEMT |
| 1.460e-02 | -4.23 | protein localization to nucleus | biological process | GO:0034504 | 154 | 30 | 16441 | 2138 |
BANP,RANBP6,FGF9,MSX1,ASUN,PLRG1,SUMO3,TOR1AIP2,TGFB2,NUP214,RPAIN,NOP58,TMCO6,TCF7L2,ABCA7,RERE,IRS1,PAF1,RANBP2,KPNA1,KPNA3,NUP133,TAF3,DNAJB6,NCKIPSD,TNPO3,RAN,BMP4,IPO11,IPO4 |
| 1.460e-02 | -4.23 | chr5q13 | MSigDB lists | chr5q13 | 53 | 13 | 17758 | 2279 |
PTCD2,POLK,MARVELD2,VCAN,UTP15,COL4A3BP,MRPS27,ANKDD1B,ADAMTS6,ENC1,GFM2,HMGCR,PDE8B |
| 1.461e-02 | -4.23 | GAGCCAG,MIR-149 | MSigDB lists | GAGCCAG,MIR-149 | 137 | 27 | 17758 | 2279 |
TCF12,MPI,LSM12,TNXB,RAP1B,DLG4,USP10,MARCKSL1,ARID1A,SLC6A8,CYB5B,NCDN,OXSR1,UBAP2,RAP1A,SERF2,LMBR1L,LUC7L3,SEC24C,CLCN6,PURB,RNF2,IGF2BP1,IQSEC2,SH3PXD2A,RPS6KB2,TOP1 |
| 1.462e-02 | -4.23 | GGTGTGT,MIR-329 | MSigDB lists | GGTGTGT,MIR-329 | 106 | 22 | 17758 | 2279 |
DNM3,PTBP2,PAX2,ARID5B,DLGAP4,OLA1,ATXN1,ZNF655,KCTD11,AHNAK,STC2,ALKBH8,PAM,CNOT6,CLDND1,NFASC,KDM5C,ERI3,LARP4B,PRKACB,MEF2C,NAV3 |
| 1.462e-02 | -4.23 | cell projection cytoplasm | cellular component | GO:0032838 | 107 | 22 | 17570 | 2233 |
IFT57,CFAP221,WLS,WDPCP,PIK3R4,DLG4,EFHC1,DNAH1,RPGRIP1L,AMBRA1,ARMC4,WDR35,DNAH17,ARL13B,ATG7,PQBP1,IFT140,CCDC40,DNAH2,DYNC2H1,MAPT,SPAG6 |
| 1.464e-02 | -4.22 | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | 76 | 17 | 17758 | 2279 |
PDK1,GPHN,WDHD1,PACS1,SSBP2,ST3GAL6,PIP4K2A,RPA1,SLC25A20,SET,ACP1,JOSD1,DTD1,ANP32B,HMBS,PCK2,MEF2C |
| 1.464e-02 | -4.22 | MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP | MSigDB lists | MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP | 76 | 17 | 17758 | 2279 |
ZNF706,CRADD,ARHGEF10,ID2,SMARCD3,CYB5B,SYNJ1,UBR4,ISG15,ESAM,RETSAT,MCAM,SNAP23,DNAH17,CELF1,GGT7,ADK |
| 1.467e-02 | -4.22 | CLN3 (ceroid-lipofuscinosis, neuronal 3) | protein interactions | 1201 | 91 | 21 | 16036 | 2270 |
SCAMP3,SIGMAR1,SFXN4,RARS2,XPO5,CCDC47,SSR4,PHGDH,CPT1A,C19orf70,SBDS,ARMC6,ATG7,SLC25A11,GEMIN4,TRIP13,HSD17B12,AUP1,SLC25A1,TMPO,TMEM33 |
| 1.469e-02 | -4.22 | YKACATTT_UNKNOWN | MSigDB lists | YKACATTT_UNKNOWN | 267 | 47 | 17758 | 2279 |
TTN,MPI,AMOTL1,CYLD,BIRC6,DPF2,TGFB2,TECTA,TTC1,PDZD2,CCDC50,CNIH3,GLYR1,ALKBH8,CHD2,ADCK4,POLR1B,MAP3K14,AMOT,PRPF19,SOBP,DPF3,HMBOX1,BDNF,PPARG,MON1A,ZNF654,FOXN3,EIF4A2,RAP1GDS1,ATG12,ZNFX1,PRDM1,SYMPK,RDH11,IRS1,LRP1B,POLE2,KIAA0355,ARNTL,INTS9,HOXA3,FTSJ1,ARHGAP12,CLU,NR2F2,MEF2C |
| 1.469e-02 | -4.22 | RESPONSE_TO_STRESS | MSigDB lists | RESPONSE_TO_STRESS | 499 | 81 | 17758 | 2279 |
PRDX6,NF1,ATRX,PLOD1,LTB4R,UBR5,RPAIN,HSPA1A,PABPC4,BRE,ASNS,XRCC2,ATRIP,NDUFA6,SERPINH1,MGLL,OGG1,HTRA2,PMS1,RTN4RL2,RFC3,ATF4,TFPI,ATOX1,BRCA1,SGK2,SERP1,RAD54B,DCBLD2,SMAD3,EXO1,MSRA,RBBP8,BRCA2,LUC7L3,ITGA2,TNFRSF1A,RAD51B,ALKBH1,NFRKB,BRCC3,EIF2B3,XRCC4,MUTYH,AOC3,TNIK,MINK1,XPC,SMAD7,VPS45,NFX1,MLH1,TGFB2,RPS6KA5,ABL1,TRIAP1,VAPB,GTF2H1,ERRFI1,FADS1,APEX1,POLA1,FOXN3,LIG4,APTX,ABCF1,HERPUD1,HSPA1B,RPA1,ANXA1,OXSR1,POLE2,GADD45A,PDLIM1,HIF1A,IRAK2,MSH3,ATM,ZAK,DDIT3,HRH1 |
| 1.470e-02 | -4.22 | CSNK2B (casein kinase 2, beta polypeptide) | protein interactions | 1460 | 267 | 51 | 16036 | 2270 |
BCCIP,CUL7,FN1,UTP14A,NPAS2,PRKAB2,CENPB,CSNK2A1,ZNF44,RPS6KA5,LRP5L,PIP4K2A,PHC2,ADH5,NRF1,EIF2S2,PPID,COPS3,IKBKB,HIRIP3,SHMT2,RNF2,CPNE7,LYST,CPSF3L,ANGPT2,TERF2,RPS6KB2,PTPRK,PFKFB4,KDM6B,PCGF3,FGF2,WDR18,BRCA1,SUPT5H,ODC1,FKBP3,EIF3H,RPA1,FBXL5,DYNC1H1,IRS1,TRIB3,PER1,CDK9,ARNTL,RPS6KB1,PPP3CC,NOLC1,BMI1 |
| 1.478e-02 | -4.21 | ACTR3 (ARP3 actin-related protein 3 homolog (yeast)) | protein interactions | 10096 | 64 | 16 | 16036 | 2270 |
METTL1,ARHGAP17,CUL7,FN1,SIRT7,HSD17B10,RANGAP1,SH3GL1,RPA1,ARPC3,TPD52L2,TNPO3,ANP32B,CORO1A,PUS1,PRKACB |
| 1.479e-02 | -4.21 | protein homotetramerization | biological process | GO:0051289 | 58 | 14 | 16441 | 2138 |
ACADS,DCTPP1,CAT,GLS,DECR1,HPRT1,EVL,HM13,PPAT,DCXR,CBR4,HSD17B10,SHMT2,IMPDH2 |
| 1.483e-02 | -4.21 | MODULE_32 | MSigDB lists | MODULE_32 | 234 | 42 | 17758 | 2279 |
CARS,EIF3C,SUCLG1,KHDRBS1,RPS29,ARFIP2,SF3A3,AARS,PABPC4,IGF2BP3,SUB1,RPS16,SRSF2,ETF1,SSBP1,RAN,FBL,PABPC1,SF3A1,TMPO,APEX1,RNMT,NARS,SFSWAP,EIF3J,POLA1,EIF4A2,RAP1B,R3HDM1,PSMA1,RAB10,EIF3H,CHAF1A,RPA1,SMARCC1,HNRNPR,RRAGA,EIF2S1,NCBP2,NOLC1,TROVE2,SRP14 |
| 1.485e-02 | -4.21 | oesophagus-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-carcinoma-squamous_cell_carcinoma | 6791 | 918 | 17775 | 2278 |
GGT1,ADAM19,GNB3,CDCP1,THOC5,CNTNAP3,CACNA1H,SBF2,CCNL2,NUP160,SYNJ1,CIAPIN1,AMBRA1,SKI,TOM1L1,PDZD2,NEK6,ZFHX3,LETM2,AP1M1,PDS5B,WIZ,ZNF148,KDM5C,HRG,MSANTD2,AVEN,SRRM2,CNTNAP3B,NRAS,RNMT,LIMA1,PTPRM,EXOC6B,UPP1,EHMT1,AP4B1,C11orf80,AKAP12,ABCC2,C10orf76,SLC50A1,SLC9A5,SLC7A1,DDX3X,AHNAK,BRCA2,BDH2,FIS1,TNNC1,CARS,BANP,HERC2,EP400,EPM2AIP1,TMEM63C,TRIP6,FAM189B,TRIO,PIK3R4,RSF1,CLINT1,PITPNM1,CHN1,RBM20,CNST,EIF2S2,DHX37,SLC38A5,APLF,INTS7,CACNB2,MED24,GEMIN4,NOC3L,CCDC88C,MAP3K12,AGL,PABPC1,SERBP1,SAMD3,ANGPT2,NOM1,HMGCR,RABEPK,GATAD2B,ZNF675,IFRD1,COL17A1,STAG1,KCNQ3,MYO10,ZNF587,RB1CC1,PRDM16,ARID5B,TYW1,EPS15L1,RYR2,USP10,MAP7D1,ST6GALNAC3,TRIM37,EVI5,NCDN,RDH11,DYNC1H1,VPS13C,TSR1,LRP1B,NME7,CLASRP,SURF1,ZNF160,GPN1,KIAA0196,WDR33,MB21D2,ARHGAP10,COG5,SDSL,ABCA3,DNM3,TRERF1,DDX18,PAFAH1B1,PDK4,DDR2,MYH9,NUP43,TUBB6,ST3GAL6,SAFB2,EEA1,STAM,RPGRIP1L,CD96,SPG21,ZSWIM7,ABCA12,ZKSCAN1,WAC,CLCN6,ATRIP,CEP63,MSH4,TMEM136,MTHFD2L,ZC3H3,DENND1A,LYST,KMT2D,STAMBP,FAM111B,ARHGEF10,SLCO6A1,PCNXL2,ATP6V0A1,TTC28,DSP,VPS53,FGFR1,PDE8B,FBXL5,ARHGAP21,CDC16,KDM4B,ASTN2,HIPK2,PAM,RPS6KB1,FUS,ZBTB11,ANKS1A,LAMA5,CEP170,CATSPERG,COMMD10,ZNF786,SHQ1,SESTD1,C1orf226,SF3A3,ATG2B,AKT1S1,IP6K2,RSRC1,SNW1,TAF3,PVRL3,ACAP3,UNC13A,LTN1,FBXL19,SAMD4A,SOX6,HNRNPM,LYPLA2,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,FBXO17,ZC3H18,FRA10AC1,LDHA,RSBN1,CCDC113,FAM126B,ZNF467,PPIP5K2,CASC1,DDX49,UBC,CCDC150,OXSR1,ETFDH,SRCAP,NSD1,BAZ2B,PXDN,POLE2,HERC1,ACOX1,SRD5A3,SLCO5A1,PTPN4,BMP4,GPAM,SORCS2,DOCK6,ANAPC4,GPATCH4,CUL7,FAM227A,RBM33,GPBP1L1,TFIP11,CSNK2A1,RNF43,TTI1,TMEM132A,NLE1,FRRS1,ABL2,AMPD3,ECM1,PHF5A,ARHGAP18,MARVELD2,XRCC2,ANKRD11,METTL8,TRIML2,UBAP2L,ZNF85,ETV1,VPS13B,FLNC,DSC3,DBN1,CHD9,SLC3A2,ZNF124,GCNT2,RBCK1,ATF4,ABCC4,BAZ2A,ZNF414,KATNAL1,ANK2,MED27,NOL6,GMFB,LAMA2,BRCA1,KCNH2,ODC1,ZNF91,MGST1,PEX1,KIF16B,BSN,DYRK1B,GLS,TP53BP1,CHD3,EEFSEC,TECPR2,CCDC146,SOCS4,AHNAK2,DPP4,PPP3CC,MAGI1,SARS,AOC3,MCM6,SMAD7,MAPK8IP3,FAN1,HES6,DNAH1,DOPEY1,RNF40,KIAA1958,MLX,ABCA5,CEP290,PDE10A,PPIL2,NDRG4,GTF2H1,TIMELESS,ALDH18A1,LRSAM1,TRAPPC9,CRADD,IFT43,TLE3,HOMER2,SETD2,HAUS6,WDR25,OBSCN,RNH1,ZNFX1,VAC14,TBC1D2,PWP1,NAP1L5,GRIK4,FAM135A,ITPRIPL1,SPAG9,PALB2,DNAH17,PPP1R12B,ZNF430,ARHGAP12,DDX10,RNF114,USP7,SART1,CYLD,PAPD4,ARID2,RBFOX2,LPCAT3,SSBP2,DENND3,PPP1R9A,SEMA6A,DDX60L,PLXNB1,KDM1A,CAD,METTL16,ANKRD13A,ZNF608,NRF1,JAG1,NUP133,GRIN2C,UBR1,DNAJB6,FGGY,FSIP2,ZDHHC6,ANKRD24,CCDC40,MYH15,BCAP29,ANO8,CASP10,CTC1,PRPF19,TMEM200A,KDM3B,KAT8,AKAP8L,VIM,AKAP13,NUP214,ARL5B,EIF3H,USP36,TJAP1,SMAD3,IFT81,RBBP8,SIX5,CLEC16A,ITGA2,ZNF436,INTS9,PRRT3,NFASC,ZNF589,PARD3,ATXN7L2,ZNF507,UNC13D,DMGDH,RFX1,FAM46B,MAP1S,ARFIP2,RBM19,FOXP1,POGZ,ZNF594,IQGAP2,SACS,ZNF561,CWC27,SELT,DDX31,POLR1B,CPNE7,C12orf4,HSD17B12,ADAMTSL3,LRRIQ1,FOXN3,SMARCAD1,ABCF2,KRTCAP3,TEX14,TOP3A,PEAR1,FERMT2,ARHGEF12,RANGAP1,HIST1H4J,PALLD,PIK3CB,ARMC3,POLR3G,ZRANB3,DKK1,CACNB1,TMEM237,GPC2,ADAT2,SET,BCAS3,FNTB,DNAJC12,USP20,TMEM219,ZNF32,RBPJ,TAF12,ITGB4,NR2F2,KIF1B,ZNF292,POLB,MYCBP2,CGN,CUL4A,LUZP1,TNFRSF21,PRKCA,LRP5L,AARS,UBR5,GABPB2,MGA,GIPR,CHD2,ME1,CEP135,SPAG6,ZNF646,TBC1D8,GDAP1,DPF3,ATG9A,ALDH1L2,NOL8,CUX1,TCEB3,CAMSAP2,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,GNAI1,DOT1L,SPOP,SKIL,TRRAP,SH3RF1,CCNT1,HSPBAP1,ZNF81,VPS13D,SEMA3C,GREB1L,DNAH2,NRP1,WDR66,FAM118A,RFXAP,ZNF598,SPOCK2,PTPN14,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,LARS2,DLGAP4,OPHN1,GTF2IRD1,TGFBR2,MTUS1,IGF2BP3,FAM192A,PRKCE,TECTA,HR,PI4KB,ZNF586,ENTPD5,NOVA2,ASAP1,SCAF1,USPL1,VWDE,IGF2BP1,CNOT4,LPCAT1,FDFT1,ADARB1,SCAF11,RREB1,AOC2,PCCA,RAP1GAP2,KIAA0586,RAP1B,PTPN12,ARID1A,TPRA1,PLCB1,EHBP1,MTR,LYRM7,DAGLA,ZNF425,EPRS,ASCC3,KIDINS220,HIF1A,NSF,VCAN,SPEN,ZZEF1,D2HGDH,BIVM,ZCCHC6,RIOK3,PEX13,NCOR1,CNDP2,CPT1C,RTTN,AMOTL1,TRPM2,BIRC6,SPATA2L,URB2,RIBC2,HFM1,KIAA0232,C1QTNF7,KLHL18,SPATS2L,PLEK2,PTPRG,AP1B1,CORO6,LTB4R,FLNB,IGSF1,CHD7,NUBPL,ZNF827,DECR1,KDM2A,LPIN2,DTNBP1,SHF,NBEA,TTC3,SERPINH1,KMT2A,CDK12,CASP8AP2,ZCCHC14,RFC4,BRD4,RFC3,GON4L,C1orf228,SFXN4,MTIF2,DLG4,PNN,GALK2,TBC1D16,STK10,ERC1,DHX57,BAZ1A,WDR5B,SMARCC1,ZNF236,LARGE,ALKBH1,IFT140,MDN1,ANXA2,PDCD11,XRCC4,NOLC1,TROVE2,NCOR2,SSH2,BRAF,SCAMP3,CA11,TTC27,B4GALT5,C10orf2,TCF3,KIF5C,SLC25A12,FARS2,MLH1,MON2,OPA1,GDPD5,INPP1,GIGYF2,MAD2L2,ABL1,ZNF239,NEBL,LRP2BP,NISCH,SDCBP2,UPF2,RDX,COPS7B,DYNC2H1,ERRFI1,PLEKHG4,NAV3,FER1L5,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,BMS1,OASL,GUF1,YIF1A,ZFP62,KLHL22,FBXO21,ZNF155,IREB2,DDX50,HELZ,HNRNPH3,ATM,SVIL,MYOM2,APAF1,BRWD3,IPO4,DDIT3,STK4,PHF3,NF1,KIF5A,SLC52A3,FANCD2,TRPM6,ZNF107,PLOD1,ANKRD18A,SLC29A1,BCOR,SNAPC4,SLC30A7,ZNF804A,SRPRB,DST,ANAPC1,YLPM1,CNIH3,GPR87,MYH3,IPP,ZEB1,PCOLCE2,POLR3B,SLC27A5,SLC35C2,HCFC2,CCDC121,PRKACB,LONP1,CEP128,ELOF1,TIMM50,LAMA4,DTNB,DEAF1,GPM6A,TXLNG,CMIP,VWCE,GPCPD1,MINA,KSR2,KMT2C,ST3GAL5,TIMM44,CHAF1A,UBTF,TMEM132B,GEMIN5,EIF4ENIF1,SUFU,DNAJC1,CC2D1B,MKL2,CTAGE5,CSMD3,ABCC3,ASB3,GALNT10,ZC3H8,MTCH1,VIPR1,SLC12A7,FN1,RHOBTB1,SEC24D,TAF1,DPF2,MED13L,PHGDH,CEP164,SIPA1L3,ZNF354A,ATXN2,SEMA3D,PRF1,NRIP1,AKAP11,N4BP2,HSD17B14,ZNF234,KRT20,TSTA3,TRA2A,ELP3,JMJD1C,WBSCR22,WWC1,LIG4,PRDM1,CORIN,ANKRD20A4,AGAP1,DNAH14,UBE2E1,ISG15,POP1,APBB3,SYCP2L,ATAD5,MYBBP1A,INTS5,FAT1,KIAA0754,SDCCAG8,EXOC4,KIAA1328,TBL1X,TMEM182,PDSS2,ZBTB24,DMXL2,FEZ2,ASH1L,PCNT,CELSR3,SLC5A5,PSTPIP2,MYO7A,SMARCA4,COBLL1,TBCCD1,ST7L,GBF1,DHX35,ZSCAN5A,ZC3H13,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,CBR4,PPFIBP1,SNTG2,MET,CPSF3,ITGAX,VCL,TMEM120B,HTRA2,MAML3,ACSL5,NARS2,ANTXR2,PHLDB2,COL5A2,PTBP2,PARP2,ATXN1,POU2F1,DKC1,ATP8B2,UBR4,C1orf174,RAB10,S100A16,TPK1,RAD54B,ARMC4,IKZF4,CEBPZ,ARNTL,SRFBP1,FKBP5,DISP1,HEATR1,BRD9,SMG1,KLHL24,TNIK,DYM,NSUN6,CLSTN2,PPHLN1,WDR26,IGF2BP2,ATF7IP,SEMA3E,FAM49A,BMP6,HDDC2,SFI1,MAN1A1,IL17RE,GART,CTNNBL1,SEC24C,DSG2,CLDND1,TTC17,LDLRAD3,ERI3,AMOT,MICAL3,RPS6KB2,KDM6B,SLC6A16,MSX1,FGF2,CRIM1,KDM5A,TEAD1,PPP1R21,METTL23,ASAP3,SCMH1,ARHGAP32,PDE2A,MEN1,ZNF407,NAALADL2,NAPEPLD,SYMPK,TARS,MFN2,CTIF,DAGLB,GADD45A,SERINC1,AGTPBP1,ZRANB2,MMP16,ZSWIM6 |
| 1.486e-02 | -4.21 | viral process | biological process | GO:0016032 | 694 | 110 | 16441 | 2138 |
USP7,CHMP2A,THOC5,CUL7,RAB11FIP4,CUL4A,UBN1,MFGE8,RPS29,NUP43,AP1B1,NUP160,GBF1,HSPA1A,SMARCB1,VPS18,RPS16,SHC1,NUP133,PPID,AP1M1,RAN,HCFC2,SEH1L,CARM1,RBCK1,BRD4,KRT7,RNMT,RAB7A,NFIA,TCEB3,VIM,CAV1,NUP214,UBR4,CXADR,CDHR3,TAF9B,DDX3X,TAF2,SMAD3,RANBP2,SUPT4H1,KPNA3,CCNT1,HIPK2,ITGA2,ATG7,TNFRSF1A,H2AFX,DPP4,SCARB1,COPS6,XRCC4,AP2S1,CHMP4C,EFNB2,TAF1,SUPT6H,ANKRD17,VTA1,NFX1,ATF7IP,GAS6,TRIM22,PSMF1,POM121,NEDD4,ELL,SNW1,UBE3A,TAF3,BANF1,GTF2H1,VAPB,LRSAM1,CAV2,TOP1,GTF2H3,VPS37A,POLA1,EIF4A2,LIG4,PSMA1,PACS1,SUPT5H,NELFA,VAC14,UBC,ISG15,POLR2A,HSPA1B,SRCAP,BICD1,KPNA1,SYNCRIP,GTF2A1,RPL28,CDK9,SPEN,VPS37B,SET,CUL2,TAF4,FDPS,RRAGA,NCBP2,TAF12,SLC52A2 |
| 1.488e-02 | -4.21 | IGARASHI_ATF4_TARGETS_DN | MSigDB lists | IGARASHI_ATF4_TARGETS_DN | 88 | 19 | 17758 | 2279 |
SLC3A2,ATF4,PSAT1,SEC24D,RHOBTB1,ANK2,KIAA0232,TRAK1,PHGDH,TRIM37,ATP9B,KPNA1,ASNS,NEBL,KLF4,DSG2,STC2,SUCLG2,PCK2 |
| 1.490e-02 | -4.21 | signal sequence binding | molecular function | GO:0005048 | 36 | 10 | 16491 | 2164 |
RANBP6,PEX7,BRE,KPNA1,KPNA3,CEMIP,SRP68,TNPO3,SRP14,IPO4 |
| 1.493e-02 | -4.20 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | 169 | 32 | 17758 | 2279 |
TTN,ZNF516,NPAS2,LAGE3,PRKCA,PHGDH,TGFBR2,FOXP1,AARS,MGA,FLNB,C6orf48,NBEA,PRICKLE2,MTHFD2L,MYB,SETD1B,PDK1,TTC28,PDE3B,CCDC3,ZNF708,TOM1L2,HIPK2,ATM,TBL1X,SCARB1,GGT7,USP11,PDE9A,LAMA5,SLC16A10 |
| 1.498e-02 | -4.20 | V$CREB_01 | MSigDB lists | V$CREB_01 | 254 | 45 | 17758 | 2279 |
CHMP2A,CYLD,BRAF,ID1,NF1,MAP3K13,PAFAH1B1,ZBTB37,DDX19A,RPS29,OSBPL9,PPP2R2A,RCAN1,BRE,MCAM,SUV39H2,SREBF2,THADA,INTS7,VGF,IKBKB,ANAPC10,RELB,ZMYM2,CTC1,DDX28,SLC38A1,LDHA,SULT4A1,PACRGL,TEX14,MRRF,GNL1,SNAP25,MBNL2,NUP214,DNTTIP1,CAMK2D,SPAG9,ADNP,TRAP1,PER1,VPS37B,UMPS,ZBTB11 |
| 1.498e-02 | -4.20 | WHITFIELD_CELL_CYCLE_G1_S | MSigDB lists | WHITFIELD_CELL_CYCLE_G1_S | 131 | 26 | 17758 | 2279 |
PMS1,MCM6,GINS3,ZNF414,FAM111B,TRA2A,MRI1,AP4B1,KIAA1586,PNN,EIF2A,NUP43,LENG8,MCM2,CHAF1A,ABCA7,PCDH7,FLAD1,ACD,VPS72,LUC7L3,MCM5,HSPB8,ZRANB2,RUNX1,CASP8AP2 |
| 1.498e-02 | -4.20 | ONDER_CDH1_TARGETS_1_UP | MSigDB lists | ONDER_CDH1_TARGETS_1_UP | 131 | 26 | 17758 | 2279 |
KLHL24,CADM4,ZNF516,SEC24D,THSD4,KCNMA1,DLGAP4,SEMA3F,CHAC1,PRKCA,PHGDH,TMEM187,ASNS,YIPF2,HERC1,PPFIBP1,PER1,SLC39A7,STC2,PTGS1,SSBP1,PCK2,CD44,ZMYM2,ZMAT3,N4BP2L2 |
| 1.504e-02 | -4.20 | ZnF_U1 | smart domains | SM00451 | 25 | 8 | 9131 | 1249 |
RBM20,ZNF622,ZFHX3,ZNF346,ZMAT2,ZNF407,ZMAT3,ZFHX2 |
| 1.509e-02 | -4.19 | E2F1_UP.V1_DN | MSigDB lists | E2F1_UP.V1_DN | 182 | 34 | 17758 | 2279 |
VPS45,TNXB,HES6,WDR26,SLC6A8,LCLAT1,SLC1A1,AMPD3,MMP7,MLX,MYC,TANK,NDRG4,GSTA4,PTGS1,ADARB1,LAMA4,HBG2,LIMA1,MCL1,NHSL1,CPT1A,ANGPTL4,ANXA1,PGD,ZC3H12A,PLIN2,TRIB3,GADD45A,SIX5,VCAN,ACOX1,MDN1,SYNPO |
| 1.509e-02 | -4.19 | GSE27786_LSK_VS_NKCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKCELL_UP | 182 | 34 | 17758 | 2279 |
PIGN,MFGE8,TMEM177,NOP56,DDX56,GART,FGGY,COPS3,NISCH,GPATCH1,BCAP29,PCK2,SLC25A23,IPO11,MTHFD1,TRIM13,IL11RA,RNMT,PSPC1,WDPCP,EHBP1,CLNS1A,YTHDF2,RDH11,RETSAT,CDC16,H2AFX,ALKBH1,PEX13,PUS1,POLR1C,TXN2,PDSS2,IPO4 |
| 1.509e-02 | -4.19 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 182 | 34 | 17758 | 2279 |
KLHL24,BCKDK,H2AFJ,DLGAP4,MAPK8IP3,HES6,CCDC47,FOXP1,FAM49A,ESAM,NOP16,UPF2,NT5C,LDLRAD3,ZNF710,SLC35C2,SLC25A23,LRRC20,KDM3B,TSPYL4,RAP1GAP2,ATP8B2,TRIM37,STK10,CCDC28B,DYNC1H1,SUPT4H1,ATAD5,HERC1,HIPK2,DUSP19,SENP3,MBD6,RNF114 |
| 1.512e-02 | -4.19 | NCL (nucleolin) | protein interactions | 4691 | 219 | 43 | 16036 | 2270 |
CUL7,CUL4A,EIF3C,FN1,SUPT6H,SIRT7,NFX1,CSNK2A1,NOP56,ANAPC1,RPS16,PHF5A,MYC,RDX,PTGS1,RNF2,ANP32B,FBL,PRMT5,KMT2A,PABPC1,TERF2,TOP1,MYB,RPS6KB2,NPM3,RANGAP1,MCM2,SUPT5H,EIF5B,UBC,RPA1,GZF1,SUPT4H1,MYBBP1A,COPS5,TAF4,CUL2,H2AFX,COPS6,POLR1C,BMI1,RFXAP |
| 1.514e-02 | -4.19 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN | 195 | 36 | 17758 | 2279 |
NCOR2,ACTR3,KLHL18,LPCAT3,SLC29A1,AP1B1,NDUFS7,PCDH7,SH2B3,ABL1,NPRL2,SHC1,ZFHX3,SREBF2,ATXN2,CFDP1,VPS52,ANXA5,GTF2H1,KIAA0922,SNAPC5,TSTA3,ITPA,PCMT1,USP10,TRIM37,STK10,RERE,SLC23A2,PAF1,PES1,CTAGE5,IQSEC2,PDCD11,KIF1B,ZBTB24 |
| 1.514e-02 | -4.19 | GSE17721_POLYIC_VS_CPG_1H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_1H_BMDM_DN | 195 | 36 | 17758 | 2279 |
IMMP2L,SEC24D,SUPT6H,C16orf45,LAMTOR3,SMAD7,KDM1A,SLC39A11,RTN1,SLC38A2,INTS12,ETF1,MSH4,ERRFI1,TOP1,DTNB,RREB1,CLYBL,SFXN4,TFPI,SMARCD3,TTYH2,DLST,UBC,MLLT10,DCBLD2,SKIL,APBB3,KPNA3,SERINC1,HK2,LARGE,APAF1,NFKBIB,MTMR1,KDM4C |
| 1.515e-02 | -4.19 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043154 | 93 | 20 | 16441 | 2138 |
MAP2K5,PAX2,CSNK2A1,RIPK1,GAS6,NOL3,NLE1,BIRC2,HERPUD1,SNCA,DDX3X,SH3RF1,DNAJB6,KLF4,DNAJA3,TRIAP1,DPEP1,TNFRSF10D,CD44,IGBP1 |
| 1.517e-02 | -4.19 | regulation of striated muscle tissue development | biological process | GO:0016202 | 99 | 21 | 16441 | 2138 |
EFNB2,BDNF,FGF9,NRAS,FGF2,NLN,SIRT2,TCF7L2,FGFR1,DKK1,SMAD3,GATA6,ARNTL,MKL2,RPS6KB1,RBPJ,BMP4,YBX3,UQCC2,HMGCR,MEF2C |
| 1.525e-02 | -4.18 | Dual Incision in GG-NER | REACTOME pathways | R-HSA-5696400 | 40 | 11 | 8202 | 1117 |
GTF2H3,RFC4,RFC3,CUL4A,POLE2,GTF2H2C,POLK,PARP2,GTF2H1,UBC,RPA1 |
| 1.526e-02 | -4.18 | human chr14q22.2 | chromosome location | human chr14q22.2 | 6 | 3 | 26250 | 2590 |
WDHD1,SAMD4A,GMFB |
| 1.533e-02 | -4.18 | V$NRF2_01 | MSigDB lists | V$NRF2_01 | 261 | 46 | 17758 | 2279 |
INSIG2,NF1,WDR74,PRKCSH,ITFG1,UBXN1,AKT1S1,CUTC,EDC3,SHC1,ZFHX3,SEC24C,AP1M1,VPS52,ARHGAP1,CELF1,KDM5C,AGL,PRKACB,SERBP1,CSGALNACT2,PRPF19,HMBOX1,TIMM8B,NRAS,TFCP2,AKAP12,ARL5B,DLST,VPS53,PHF6,BAZ1A,TMCO1,DDX50,PALB2,DNAJC1,E2F4,INTS9,CCDC85B,TNFRSF1A,PTRH2,EIF2S1,ZBTB11,DDIT3,LRRC41,STK4 |
| 1.538e-02 | -4.17 | Plipid/glycerol_acylTrfase | interpro domains | IPR002123 | 17 | 6 | 18293 | 2341 |
GPAM,LPCAT1,LCLAT1,AGPAT4,LPCAT2,GPAT3 |
| 1.540e-02 | -4.17 | MORF_SS18 | MSigDB lists | MORF_SS18 | 59 | 14 | 17758 | 2279 |
TAF2,SEC31A,RBBP8,ATRX,PRKCSH,CHD3,FAM189B,SFSWAP,SLC25A11,PARN,ZBTB11,PIK3CB,MFN2,RERE |
| 1.542e-02 | -4.17 | TOP2A (topoisomerase (DNA) II alpha) | protein interactions | 7153 | 75 | 18 | 16036 | 2270 |
CUL7,FN1,SMARCAD1,CSNK2A1,BRCA1,PRKCA,RING1,ISG15,RPA1,RANBP2,MYC,COPS5,E2F4,GLYR1,CUL2,BMI1,TERF2,TOP1 |
| 1.542e-02 | -4.17 | HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2 (H')) | protein interactions | 3188 | 75 | 18 | 16036 | 2270 |
MSI2,CUL7,FN1,PRPF31,RBFOX2,GMFB,PLOD1,MBNL1,HNRNPA3,COPS5,CUL2,PQBP1,GPN1,HIBCH,COPS6,SERPINH1,YARS,SRPK2 |
| 1.542e-02 | -4.17 | SEPT2 (septin 2) | protein interactions | 4735 | 75 | 18 | 16036 | 2270 |
SART1,FN1,UTP14A,TRA2A,ZC3H18,CSNK2A1,SON,ISG15,SNCA,RNF40,SNW1,STX1A,ADNP,SNX24,ZNF326,SEPT5,SRRM2,HNRNPM |
| 1.542e-02 | -4.17 | MAPRE1 (microtubule-associated protein, RP/EB family, member 1) | protein interactions | 22919 | 75 | 18 | 16036 | 2270 |
CYLD,TUBA1A,FN1,PAFAH1B1,TRIO,OLA1,PIK3R4,PSMA1,SUMO3,HSPA1A,DST,NAV1,POLE2,COPS5,PQBP1,PRKACB,NAV3,SPTAN1 |
| 1.543e-02 | -4.17 | MCM | smart domains | SM00350 | 8 | 4 | 9131 | 1249 |
MCM6,MCM2,MCM9,MCM5 |
| 1.544e-02 | -4.17 | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | 163 | 31 | 17758 | 2279 |
IL11RA,ITPRIP,CLK1,UPP1,ARRDC3,RAP1GAP2,PDE4B,VTI1A,MEF2D,TIGD1,SOX4,FOSL2,ENC1,FAM8A1,SLC26A11,PLCXD2,TCF7L2,ANXA1,SKIL,ZFAND3,MSX2,ZDHHC11,GADD45A,ZFYVE28,KLF4,PPP1R12B,C3orf35,FHIT,TNFRSF10D,SOX6,KAT6A |
| 1.549e-02 | -4.17 | hypothalamus | COSMIC cancer mutations | hypothalamus | 17 | 6 | 17775 | 2278 |
RNF130,BRAF,NRAS,KIAA1549,GNAI1,CLCN6 |
| 1.549e-02 | -4.17 | ovary-low_malignant_potential_(borderline)_tumour-mucinous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-mucinous | 37 | 10 | 17775 | 2278 |
BRCA2,SRSF2,BRAF,NRAS,RNF43,BRCA1,ARID1A,MET,MAP2K4,FGFR1 |
| 1.553e-02 | -4.17 | SF3B1 (splicing factor 3b, subunit 1, 155kDa) | protein interactions | 23451 | 160 | 33 | 16036 | 2270 |
SART1,MCM6,CUL7,FN1,PRPF31,PLRG1,SIRT7,SF3A3,CSNK2A1,TOX4,PHF5A,MCM5,MYC,UBAP2L,ZNF326,RNF2,SSBP1,SRRM2,LONP1,HNRNPM,TOP1,SF3A1,PRPF19,TFPI,ATG12,MCM2,SON,RPA1,EPRS,HNRNPR,COPS5,PRPF4,TPM1 |
| 1.558e-02 | -4.16 | human chr19q13.11 | chromosome location | human chr19q13.11 | 34 | 8 | 26250 | 2590 |
KIAA0355,LSM14A,GPATCH1,LOC400684,SCGB2B2,PDCD5,LRP3,ZNF507 |
| 1.559e-02 | -4.16 | LE_SKI_TARGETS_UP | MSigDB lists | LE_SKI_TARGETS_UP | 17 | 6 | 17758 | 2279 |
HMGA2,ADAMTS6,ITGB4,CD44,NRP1,HSPB8 |
| 1.559e-02 | -4.16 | MYOBLAST_DIFFERENTIATION | MSigDB lists | MYOBLAST_DIFFERENTIATION | 17 | 6 | 17758 | 2279 |
TTN,IFRD1,BMP4,MBNL1,TBX3,CACNA1H |
| 1.559e-02 | -4.16 | chr4q24 | MSigDB lists | chr4q24 | 17 | 6 | 17758 | 2279 |
INTS12,SLC9B2,GSTCD,TBCK,LAMTOR3,BDH2 |
| 1.559e-02 | -4.16 | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | MSigDB lists | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | 17 | 6 | 17758 | 2279 |
TRIB3,GADD45A,PDK4,HERPUD1,INTS9,RERE |
| 1.559e-02 | -4.16 | TOMIDA_METASTASIS_DN | MSigDB lists | TOMIDA_METASTASIS_DN | 17 | 6 | 17758 | 2279 |
SARS,GARS,TRIP6,CLK1,FOXC1,WARS |
| 1.559e-02 | -4.16 | KYNG_WERNER_SYNDROM_UP | MSigDB lists | KYNG_WERNER_SYNDROM_UP | 17 | 6 | 17758 | 2279 |
LIG4,MBNL2,NSMCE1,C15orf41,ITGA2,FRA10AC1 |
| 1.559e-02 | -4.16 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | MSigDB lists | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | 17 | 6 | 17758 | 2279 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 1.559e-02 | -4.16 | KIM_PTEN_TARGETS_UP | MSigDB lists | KIM_PTEN_TARGETS_UP | 17 | 6 | 17758 | 2279 |
RCHY1,GPM6A,GALNT10,SKAP2,SLC7A11,BUD31 |
| 1.559e-02 | -4.16 | CHROMATIN_REMODELING_COMPLEX | MSigDB lists | CHROMATIN_REMODELING_COMPLEX | 17 | 6 | 17758 | 2279 |
RSF1,ARID1A,SMARCC1,ARID1B,CHAF1A,SMARCB1 |
| 1.560e-02 | -4.16 | GINS4 (GINS complex subunit 4 (Sld5 homolog)) | protein interactions | 84296 | 29 | 9 | 16036 | 2270 |
GINS3,POLA1,MCM5,LAGE3,WDHD1,AHCYL1,IGBP1,PPIL3,NCDN |
| 1.560e-02 | -4.16 | PDLIM1 (PDZ and LIM domain 1) | protein interactions | 9124 | 29 | 9 | 16036 | 2270 |
SUPT4H1,CUL7,PDLIM1,HK2,VIM,IGBP1,RPS6KA5,CLNS1A,ARIH2 |
| 1.560e-02 | -4.16 | BRF2 (BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit) | protein interactions | 55290 | 29 | 9 | 16036 | 2270 |
SLC3A2,TNPO3,MARS,GEMIN4,XPO7,SNAPC4,XPO6,IPO4,TMEM33 |
| 1.560e-02 | -4.16 | TIA1 (TIA1 cytotoxic granule-associated RNA binding protein) | protein interactions | 7072 | 29 | 9 | 16036 | 2270 |
MPI,CUL4A,FN1,FMNL1,COPS5,CUL2,PITPNB,BMI1,HTRA2 |
| 1.563e-02 | -4.16 | chr10p12 | MSigDB lists | chr10p12 | 37 | 10 | 17758 | 2279 |
ARMC4,ARHGAP21,NEBL,MPP7,CACNB2,WAC,NRP1,ARMC3,MKX,MLLT10 |
| 1.563e-02 | -4.16 | SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS | MSigDB lists | SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS | 37 | 10 | 17758 | 2279 |
PTP4A1,JAG1,MMP7,ADAM9,RBPJ,CD44,CDK6,BIRC2,FGFR1,KDM4C |
| 1.563e-02 | -4.16 | CHEN_HOXA5_TARGETS_9HR_DN | MSigDB lists | CHEN_HOXA5_TARGETS_9HR_DN | 37 | 10 | 17758 | 2279 |
UBTF,FAM127A,SYNGR2,H2AFX,GLG1,SLC29A1,GEMIN4,SERPINH1,LPCAT1,MAT2A |
| 1.564e-02 | -4.16 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | 176 | 33 | 17758 | 2279 |
MYCBP2,IFT57,EGR1,FOXO1,ST6GAL1,ZFP36L1,SSBP2,DENND3,UBR5,CHD7,AMPD3,SIPA1L3,MBD2,MYC,KIAA0922,PLEKHA2,LYST,NT5E,EVL,IFNGR2,TUBA1A,ARID5B,CA5B,SLC50A1,PDLIM1,HK2,AEN,ATM,TBL1X,SYNPO,SPOCK2,KDM4C,DDIT3 |
| 1.567e-02 | -4.16 | CSAPPISMRASE | prints domains | PR00153 | 22 | 6 | 4759 | 462 |
PPIL1,RANBP2,PPID,CWC27,PPIL3,PPIL2 |
| 1.572e-02 | -4.15 | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 189 | 35 | 17758 | 2279 |
XPC,TRAK1,CSNK2A1,MYH9,RTN4,NBEAL1,RPS6KA5,C1orf159,ADH5,RNF141,GART,ARHGAP18,COQ3,PTPRK,TUBA1A,FGF2,RB1CC1,ANKMY2,RDH10,PTPN12,SETD7,PDE2A,ATP8B2,TTC28,CRYBG3,ZNF251,SPOP,DAGLB,ARL4A,LRRC40,BIVM,AEN,ECHDC1,SLC25A26,METTL2B |
| 1.572e-02 | -4.15 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | 189 | 35 | 17758 | 2279 |
SEPHS2,RARS2,WDR13,VARS,PAG1,NEDD4,INTS7,TBC1D22A,PYCRL,MED24,SUCLG2,PRADC1,KDM3B,DDHD1,ACSL5,ANAPC13,PDK1,PPP1R21,ARHGAP39,RAP1GDS1,ARID1A,LENG8,KRTCAP2,C1orf174,GNAI1,CAT,EHMT2,COQ9,CDK9,SET,CTAGE5,GPN1,DTD1,PSAP,NRP1 |
| 1.572e-02 | -4.15 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 189 | 35 | 17758 | 2279 |
ZNF76,SH2D3A,TTC27,OLA1,QSER1,BZW2,MFHAS1,ADH5,RPS16,ZNHIT6,SUCLG2,MAP3K14,FBL,CASP8AP2,PRKACB,NIPSNAP1,METTL1,GPM6A,EHMT1,RPA1,PWP1,FBXO21,KIAA0355,MKL2,GLG1,PAM,ATM,IFT140,COPS6,ADK,TXN2,NOLC1,NMD3,SPOCK2,TROVE2 |
| 1.572e-02 | -4.15 | GSE3982_MAST_CELL_VS_TH1_UP | MSigDB lists | GSE3982_MAST_CELL_VS_TH1_UP | 189 | 35 | 17758 | 2279 |
DROSHA,ZHX3,ARL15,TMEM183A,CCNL2,PHLDA2,PSMF1,AHCYL2,LPIN1,ZNF804A,DOPEY1,EXOC1,YLPM1,HARS2,S100A14,SERPINH1,VCL,LYST,TRIM13,LAMC1,RAB7A,EIF4A2,HOMER2,TBXAS1,BCS1L,ATG12,CAMSAP2,TMEM123,PTK2,ANXA1,HLCS,PMEPA1,FAT1,HERC1,COG5 |
| 1.572e-02 | -4.15 | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 189 | 35 | 17758 | 2279 |
PRDX6,RHOBTB1,B4GALT5,BCOR,RLF,SH2B3,PMAIP1,MAD1L1,MTHFD2L,SEH1L,HNRNPM,VOPP1,KDM6B,DEAF1,ZCCHC14,WARS2,PXN,ZNF124,EIF3J,TLE3,RAP1GAP2,PITPNB,CYB5B,MTR,HLA-DMA,DDX50,KPNA1,SYNCRIP,KLF4,POLR3E,VPS37B,GPN1,KLHDC4,PSAP,CNDP2 |
| 1.572e-02 | -4.15 | GSE7852_LN_VS_THYMUS_TREG_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_UP | 189 | 35 | 17758 | 2279 |
SLC12A7,TTN,CDCP1,KIAA0232,KIF5C,ATF7IP,BCOR,PRKCA,LCLAT1,FLNB,LPIN1,PRKCE,HVCN1,MARVELD2,ACOT11,ETV1,NT5E,ANTXR2,ABCC4,FOXN3,NFIA,PEAR1,ARHGEF12,PACS1,PDE2A,TMEM175,MAT2A,USP36,BTBD11,TASP1,D2HGDH,TNFRSF1A,GALNT10,PDCD11,SYNPO |
| 1.572e-02 | -4.15 | GSE17721_4H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDM_UP | 189 | 35 | 17758 | 2279 |
SPRYD7,NDUFB5,PRAF2,CHCHD10,NUP160,CMTM3,MFSD10,HDDC2,TOX4,FKBP1A,ANKRD13A,RPS16,SLC38A5,MET,LPCAT1,PRMT3,SEH1L,HMGCR,ANAPC13,LSM12,COTL1,BRCA1,C19orf70,ATP5D,CAMK2D,LSS,IKZF4,MBTD1,TNFRSF1A,TSSC1,EXOC4,SLC4A7,ANXA2,TSPAN5,MEF2C |
| 1.572e-02 | -4.15 | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDM_DN | 189 | 35 | 17758 | 2279 |
AK2,TMEM183A,C1orf52,RBM19,SCAF8,FLNB,FKBP1A,KCTD11,EIF2S2,ASNS,ANXA7,UCHL5,ZDHHC6,MMP14,ANXA5,ZEB1,LARP4B,ETV1,NUDC,HARS,WDFY3,FZD3,PITPNB,PALLD,RAB10,RANBP2,FSCN1,COPS5,HNRNPH3,HSPB8,ZNF436,RIOK3,NOLC1,IPO4,LPP |
| 1.572e-02 | -4.15 | GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_DN | MSigDB lists | GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_DN | 189 | 35 | 17758 | 2279 |
UNC13D,TMEM63C,SULT1C2,TRIM16,SEC24D,WDR13,TRPM6,TRAK1,TBCCD1,SPATS2L,ZNF44,PRKCE,STC2,ZNF142,SHMT2,ZNRD1,PPM1K,TLCD1,ZNF414,TMEM126A,TOP3A,TRAPPC6B,RBM28,SLC9A5,SAP30BP,S100A16,WARS,BAZ1A,RHOU,YIPF2,TIMM17A,TBX3,TMEM139,WDR33,TRIM36 |
| 1.575e-02 | -4.15 | cellular response to external stimulus | biological process | GO:0071496 | 245 | 44 | 16441 | 2138 |
CYP24A1,FOXO1,EGR1,PDK4,SLC2A1,PIK3R4,ATG2B,GAS6,SIRT2,BMP6,WNT2B,NPRL2,MMP7,ASNS,SREBF2,PMAIP1,MAP3K14,CASP8AP2,SEH1L,FADS1,PPP1R9B,ATF4,CRADD,MIOS,PPARG,UPP1,HSPA5,LDHA,ATG12,CAV1,PDE2A,TCF7L2,VDR,MYBBP1A,GADD45A,ADNP,ATG7,RRAGA,TNFRSF1A,EIF2S1,BMP4,TXN2,MAP2K4,TNRC6A |
| 1.579e-02 | -4.15 | Znf_RING | interpro domains | IPR001841 | 316 | 54 | 18293 | 2341 |
MYCBP2,ATRX,DPF2,MEX3A,RCHY1,NFX1,RNF24,TRIM15,RNF43,HLTF,TRIM22,CHD5,BIRC2,RING1,RNF141,RNF40,RSPRY1,RNFT2,LONRF2,ANAPC11,RNF111,LTN1,TTC3,RNF2,CNOT4,LRSAM1,SCAF11,PCGF3,DPF3,TRIM13,KMT2D,RBCK1,MEX3B,BRCA1,KMT2C,TRIM37,ARIH2,BAZ1A,NSD1,RAD18,CHD3,SH3RF1,NSMCE1,RNF138,TRAF3,RNF130,CCNB1IP1,BMI1,MID1,ZNF598,RNF214,KAT6A,TRIM36,RNF114 |
| 1.581e-02 | -4.15 | cilium morphogenesis | biological process | GO:0060271 | 206 | 38 | 16441 | 2138 |
IFT57,PCNT,CELSR3,ACTR3,MKS1,CEP126,PIBF1,DNAH1,RPGRIP1L,CEP164,ASAP1,CEP290,CCDC40,DYNC2H1,ATP6V0D1,CEP83,TTLL5,CFAP221,IFT43,WDPCP,TMEM216,KIAA0586,CCDC113,TCTN1,ONECUT2,CCDC28B,ARMC4,IFT81,TMEM237,WDR35,E2F4,ARL13B,PQBP1,BBIP1,IFT140,FNBP1L,TROVE2,LAMA5 |
| 1.583e-02 | -4.15 | regulation of proteasomal protein catabolic process | biological process | GO:0061136 | 232 | 42 | 16441 | 2138 |
USP7,TAF1,UBXN1,NKD2,OPHN1,SMAD7,RCHY1,CSNK2A1,SIRT2,PSMF1,MAD2L2,RNF40,ANAPC1,NEK6,UCHL5,WAC,ANAPC11,ANAPC10,MAD1L1,FHIT,USP49,USP42,TEX14,USP10,CAV1,UBE2K,ARIH2,USP36,UBE2E1,HERPUD1,TRIB3,KLHL22,CDC16,SMARCC1,NSMCE2,SOCS4,ATM,USP20,CLU,USP11,ANAPC4,USP15 |
| 1.591e-02 | -4.14 | Selenoamino Acid Metabolism | SMPDB pathways | SMP00029 | 11 | 5 | 978 | 148 |
GGT1,SEPHS2,MARS,METTL6,MAT2A |
| 1.593e-02 | -4.14 | PTCD3 (pentatricopeptide repeat domain 3) | protein interactions | 55037 | 54 | 14 | 16036 | 2270 |
NIFK,ATF4,SYNCRIP,TRA2A,SIRT7,H2AFX,TBPL1,MPV17,TRMT10B,RNF2,IFITM2,BMI1,ZC3H3,MRPS11 |
| 1.593e-02 | -4.14 | CNBP (CCHC-type zinc finger, nucleic acid binding protein) | protein interactions | 7555 | 54 | 14 | 16036 | 2270 |
RPS16,SYNCRIP,HNRNPR,HK2,FERMT2,RSL1D1,RNF2,IGF2BP1,BMI1,NMD3,HNRNPA3,BZW2,PABPC4,IGF2BP3 |
| 1.593e-02 | -4.14 | ATP6V0D1 (ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1) | protein interactions | 9114 | 54 | 14 | 16036 | 2270 |
NDUFV1,RPS16,MCAM,NSF,ATP6V1A,ATP6V0A1,ATXN1,LIG4,YBX3,ERC1,UBC,MTCH1,ATP5D,RPA1 |
| 1.593e-02 | -4.14 | CORO1B (coronin, actin binding protein, 1B) | protein interactions | 57175 | 54 | 14 | 16036 | 2270 |
SNU13,IFT57,FN1,ACTG1,SIRT6,ACTR3,ETF1,ZRANB2,CORO1A,PRKCA,POLR1C,CEP170,TARS,NUDC |
| 1.593e-02 | -4.14 | CDK19 (cyclin-dependent kinase 19) | protein interactions | 23097 | 54 | 14 | 16036 | 2270 |
NIFK,RB1CC1,MED27,MED15,MED13L,MED24,SMARCA4,GPN1,MED18,MED16,CLU,MED20,ERC1,ZC3H13 |
| 1.593e-02 | -4.14 | TSSC4 (tumor suppressing subtransferable candidate 4) | protein interactions | 10078 | 54 | 14 | 16036 | 2270 |
TERF2IP,SNW1,PAXBP1,BCAS2,KPNA3,TFIP11,BUD31,GPATCH1,TPM1,EIF5B,CWF19L2,RSRC1,DHX35,SPTAN1 |
| 1.598e-02 | -4.14 | ZAMORA_NOS2_TARGETS_UP | MSigDB lists | ZAMORA_NOS2_TARGETS_UP | 65 | 15 | 17758 | 2279 |
SRM,IFRD1,MCM6,SUPT4H1,ACTG1,MCM5,PCSK7,APRT,RAN,MCM2,STAM,PPA1,PTPN14,BAG1,PABPC4 |
| 1.598e-02 | -4.14 | MORF_BUB1B | MSigDB lists | MORF_BUB1B | 65 | 15 | 17758 | 2279 |
RFC4,MCM6,GARS,RFC3,SKIV2L2,CEBPZ,SHMT2,MARS,MCM2,TBXA2R,YARS,ABCF1,TARS,TRIP13,NUDC |
| 1.598e-02 | -4.14 | SESTO_RESPONSE_TO_UV_C7 | MSigDB lists | SESTO_RESPONSE_TO_UV_C7 | 65 | 15 | 17758 | 2279 |
ASNS,FGFBP1,ATIC,HSPA5,PAM,LGALS1,VSNL1,MLH1,PCK2,ODC1,ADK,YARS,AARS,PGD,MTHFD1 |
| 1.599e-02 | -4.14 | V$AP1_Q2 | MSigDB lists | V$AP1_Q2 | 255 | 45 | 17758 | 2279 |
TCF12,CYP24A1,RELL2,SSH2,MINK1,ID1,MFGE8,NHS,AKT1S1,TGFBR2,LCLAT1,MMP7,UBE3A,CCDC50,ANXA7,SRPK2,FAM184A,FLNC,PPP1R9B,NRAS,LAMC1,WDFY3,BAZ2A,TEX19,JMJD1C,RAP1GAP2,NLN,ZNFX1,VIM,PRDM1,ARRDC4,KCNH2,SLC9A5,NCDN,STOML2,GNAI1,VDR,LRP1B,GADD45A,SUFU,POLR3E,HOXA3,BLMH,LPP,ATXN7L2 |
| 1.599e-02 | -4.14 | LU_AGING_BRAIN_UP | MSigDB lists | LU_AGING_BRAIN_UP | 255 | 45 | 17758 | 2279 |
SERINC5,PHF3,PRDX6,CLK1,TGFBR2,UBR5,PIP4K2A,AHCYL2,LPIN1,PLXNB1,DDIT4,NEBL,ANXA5,RDX,GREB1,ANP32B,SERPINH1,AHCYL1,AMOT,OGG1,CAV2,FADS1,SSFA2,FGF2,MYO10,RAPGEF4,RAP1B,FERMT2,VIM,TMEM123,CAV1,PALLD,PEX1,TPD52L2,AHNAK,BAZ2B,HIF1A,HNRNPH3,VCAN,SNAP23,SLC16A1,PTP4A2,PDLIM5,CEP170,LPP |
| 1.600e-02 | -4.14 | PROTEIN_DNA_COMPLEX_ASSEMBLY | MSigDB lists | PROTEIN_DNA_COMPLEX_ASSEMBLY | 48 | 12 | 17758 | 2279 |
TAF2,PTRF,CDK9,SET,MED27,MED24,PBX1,ATF7IP,MED16,RSF1,SNAPC5,CHAF1A |
| 1.603e-02 | -4.13 | mitotic nuclear envelope disassembly | biological process | GO:0007077 | 42 | 11 | 16441 | 2138 |
RANBP2,NEK6,NUP133,BANF1,NUP43,PRKCA,NUP214,NUP160,POM121,SEH1L,LPIN1 |
| 1.603e-02 | -4.13 | regulation of cardiac muscle cell contraction | biological process | GO:0086004 | 42 | 11 | 16441 | 2138 |
CAMK2D,DSC2,JUP,SCN1B,ANK2,DSG2,PDE4B,RYR2,CAV1,KCNH2,DSP |
| 1.605e-02 | -4.13 | skin-face-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-face-carcinoma-squamous_cell_carcinoma | 2109 | 302 | 17775 | 2278 |
GGT1,MYCBP2,ADAM19,DPH1,MKS1,SBF2,HLTF,HMOX2,NUP160,SYNJ1,LPIN1,NOS1AP,EXOC1,PDZD2,NEK6,ZFHX3,PDS5B,WIZ,SRRM2,SPAG6,ZNF646,NRAS,OSBP2,LIMA1,PTPRM,ALDH1L2,EHMT1,TCEB3,WDHD1,AKAP12,ABCC2,SON,AHNAK,TRRAP,SYNGR2,VPS13D,DNAH2,NRP1,TNFRSF10D,WDR66,PTPN14,TNNC1,EP400,CELSR1,ZHX3,TRIO,CCDC47,PITPNM1,IGF2BP3,SLC38A5,USPL1,INTS7,PIGG,IGF2BP1,CALN1,ZNF518B,AGL,CAV2,PABPC1,ANGPT2,GATAD2B,KCNQ3,RB1CC1,PRDM16,AOC2,PLCB1,ONECUT2,ANGPTL4,ABCF1,DYNC1H1,ZNF425,VPS13C,LRP1B,KIDINS220,VCAN,SPEN,ZZEF1,ZBTB12,BIVM,WDR33,PDLIM5,SMYD3,COG5,RTTN,PTCD2,ABCA3,NPAS2,RIBC2,HFM1,ACTR3,KIAA0232,OLA1,RING1,RPGRIP1L,PDE3A,NOP56,SLX4,PPID,GLYR1,INTS12,TTC3,SSBP1,MSH4,KMT2A,ZC3H3,DENND1A,ARHGEF10,SLCO6A1,LRRC8A,FGFR1,PDE8B,VDR,IQCH,KDM4B,ASTN2,NSMCE2,IFT140,MDN1,PDCD11,LAMA5,CATSPERG,MID1,YEATS2,LRCH1,BRAF,SESTD1,TCF3,BHLHE40,NEDD4,KRI1,TTLL11,TADA3,ABL1,ZNF239,ZNF483,RGS17,NEBL,TAF3,LRP2BP,NISCH,LTN1,UPF2,ERRFI1,NAV3,ULBP1,FAM120B,TMC7,TTPAL,TSHZ1,TTLL5,TBRG4,BMS1,UBC,YIF1A,SRCAP,IREB2,HELZ,ATM,SVIL,MYOM2,PSAP,GPATCH4,MVK,TRIM16,UBN1,NF1,POLR1A,TFIP11,MFGE8,TRPM6,RNF43,COX10,SMARCB1,DST,ZNF804A,RTN1,GPR87,ZEB1,KIAA0922,POLR3B,SLC27A5,ZNF3,TRIP13,PTPRK,VPS13B,FLNC,LAMA4,FMNL3,GPM6A,SLC3A2,ABCC4,PPARG,ANK2,NOL6,KCNH2,KMT2C,ST3GAL5,BSN,PEX1,EIF4ENIF1,GATA6,TP53BP1,CHD3,ADAM9,DPP4,CSMD3,MAGI1,SLC12A7,OXNAD1,ITFG1,MED13L,BARX2,QSER1,DOPEY1,TOX4,ABCA5,VPS72,PPIL2,CCDC112,CCDC167,N4BP2,NT5E,MTHFD1,MSI2,RANBP6,LAMC1,IFT43,JMJD1C,TBXAS1,UTP15,ZNFX1,PRDM1,CORIN,GRIK4,BICD1,HK2,EXOC4,SLC16A1,PPP1R12B,USP7,CYLD,ASH1L,PCNT,PAPD4,OLFM2,ARID2,TMEM183A,ARSJ,DENND3,PIBF1,RADIL,PPP1R9A,ZC3H13,VPS18,BRE,CAMTA2,CCDC40,RNF2,ITGAX,MET,GNG5,C6orf89,HTRA2,ACSL5,COL5A2,BTBD11,ZC3H12A,RANBP2,ZNF557,PRRT3,NFRKB,PARD3,ZNF507,ATXN7L2,DMGDH,KLHL24,HM13,C17orf80,PDE4B,LETMD1,MAP1S,IGF2BP2,IQGAP2,SACS,SCN1B,SEC24C,PCK2,KDM6B,DNMBP,ADAMTSL3,LRRIQ1,C11orf49,PALLD,POLR3A,SMPDL3B,MFN2,RERE,GPC2,TAF4,CSRNP1,BCAS3,PREPL |
| 1.606e-02 | -4.13 | Pyrimidine catabolism | REACTOME pathways | R-HSA-73621 | 12 | 5 | 8202 | 1117 |
NT5C,NT5C3A,NT5M,UPP1,NT5E |
| 1.606e-02 | -4.13 | FTHFS_2 | prosite domains | PS00722 | 2 | 2 | 11866 | 1504 |
MTHFD1L,MTHFD1 |
| 1.606e-02 | -4.13 | SAM_MT_TRM5_TYW2 | prosite domains | PS51684 | 2 | 2 | 11866 | 1504 |
TRMT5,TRMT12 |
| 1.606e-02 | -4.13 | G_BMS1 | prosite domains | PS51714 | 2 | 2 | 11866 | 1504 |
BMS1,TSR1 |
| 1.606e-02 | -4.13 | THF_DHG_CYH_1 | prosite domains | PS00766 | 2 | 2 | 11866 | 1504 |
MTHFD2,MTHFD1 |
| 1.606e-02 | -4.13 | FTHFS_1 | prosite domains | PS00721 | 2 | 2 | 11866 | 1504 |
MTHFD1L,MTHFD1 |
| 1.615e-02 | -4.13 | CHOP-ATF4 complex | cellular component | GO:1990617 | 2 | 2 | 17570 | 2233 |
ATF4,DDIT3 |
| 1.615e-02 | -4.13 | nuclear telomeric heterochromatin | cellular component | GO:0005724 | 2 | 2 | 17570 | 2233 |
SIRT6,TNKS1BP1 |
| 1.615e-02 | -4.13 | Lewy body core | cellular component | GO:1990037 | 2 | 2 | 17570 | 2233 |
ATF4,HERPUD1 |
| 1.615e-02 | -4.13 | RNA nuclear export complex | cellular component | GO:0042565 | 2 | 2 | 17570 | 2233 |
RAN,XPO5 |
| 1.615e-02 | -4.13 | DNA ligase IV complex | cellular component | GO:0032807 | 2 | 2 | 17570 | 2233 |
LIG4,XRCC4 |
| 1.615e-02 | -4.13 | nuclear pore cytoplasmic filaments | cellular component | GO:0044614 | 2 | 2 | 17570 | 2233 |
RANBP2,RANGAP1 |
| 1.615e-02 | -4.13 | DSIF complex | cellular component | GO:0032044 | 2 | 2 | 17570 | 2233 |
SUPT4H1,SUPT5H |
| 1.615e-02 | -4.13 | hyaluranon cable | cellular component | GO:0036117 | 2 | 2 | 17570 | 2233 |
HYAL1,HAS3 |
| 1.618e-02 | -4.12 | visual behavior | biological process | GO:0007632 | 53 | 13 | 16441 | 2138 |
ABL2,DEAF1,BRAF,SYNGAP1,NF1,HIF1A,NDRG4,ATXN1,NLGN3,KMT2A,PDE8B,HMGCR,HRH1 |
| 1.619e-02 | -4.12 | HNRNPR (heterogeneous nuclear ribonucleoprotein R) | protein interactions | 10236 | 190 | 38 | 16036 | 2270 |
SART1,CUL7,FN1,DDX18,KHDRBS1,TCF3,SF3A3,TIMM10,FARSA,SNW1,NDUFV1,RNF2,FBL,PABPC1,SERBP1,HNRNPM,TOP1,SPTAN1,SF3A1,SNU13,FBXW4,SMARCAD1,HSPA5,WDHD1,RHOT2,POLR2A,UBC,RPA1,DDX3X,MYBBP1A,SYNCRIP,HNRNPH3,COPS5,CDK9,CUL2,H2AFX,MPV17,BRCC3 |
| 1.620e-02 | -4.12 | MAPKAPK3 (mitogen-activated protein kinase-activated protein kinase 3) | protein interactions | 7867 | 20 | 7 | 16036 | 2270 |
PHC2,SUMO3,RNF2,COPS6,BMI1,TCF3,NEDD4 |
| 1.620e-02 | -4.12 | NOP16 (NOP16 nucleolar protein) | protein interactions | 51491 | 20 | 7 | 16036 | 2270 |
ADARB1,SNU13,MYBBP1A,NOLC1,COPS5,ZC3H3,SRPK2 |
| 1.620e-02 | -4.12 | AUTS2 (autism susceptibility candidate 2) | protein interactions | 26053 | 20 | 7 | 16036 | 2270 |
CSNK2A1,ZNF608,PCGF3,RNF2,TLE3,RING1,RERE |
| 1.620e-02 | -4.12 | HIST1H4E (histone cluster 1, H4e) | protein interactions | 8367 | 20 | 7 | 16036 | 2270 |
NFX1,SHMT2,CUL7,FN1,UCHL5,COPS5,CUL2 |
| 1.620e-02 | -4.12 | GSPT2 (G1 to S phase transition 2) | protein interactions | 23708 | 20 | 7 | 16036 | 2270 |
SHMT2,RDX,ETF1,UBR5,PABPC1,SMG1,ATG7 |
| 1.620e-02 | -4.12 | CHD7 (chromodomain helicase DNA binding protein 7) | protein interactions | 55636 | 20 | 7 | 16036 | 2270 |
SMARCA4,VARS,ARID1A,SMARCC1,ARID2,SIRT7,TERF2 |
| 1.620e-02 | -4.12 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | 170 | 32 | 17758 | 2279 |
PTP4A1,BANP,EGR1,ID2,CHAC1,BHLHE40,SLC9B2,ST3GAL6,PHLDA2,DDIT4,SFR1,ABL2,PMAIP1,CYB5D1,SLC38A2,FNIP2,ERRFI1,N4BP2,SESN2,SLC3A2,FERMT2,PHACTR2,KLF6,ARL5B,DENND4A,NEU1,ZC3H12A,RBBP8,SPAG9,GADD45A,GTF2A1,CSRNP1 |
| 1.622e-02 | -4.12 | RNPS1 (RNA binding protein S1, serine-rich domain) | protein interactions | 10921 | 143 | 30 | 16036 | 2270 |
USP7,SNU13,CUL7,DDX41,SKIV2L2,GNL3,SFSWAP,TRA2A,ZC3H18,CSNK2A1,PNN,TAF2,RARS,SRSF2,MYBBP1A,LUC7L3,COPS5,CUL2,SDCBP2,RNF2,UPF2,GEMIN4,FIP1L1,WDR33,SRRM2,BMI1,HNRNPM,CLK2,SRPK2,PRPF19 |
| 1.631e-02 | -4.12 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | 183 | 34 | 17758 | 2279 |
PGPEP1,AUH,TRAK1,PLA2G12A,MRPS11,PAIP2,KIAA1958,TBC1D22A,WDR27,PPIL2,CTC1,KDM3B,FADS1,PCGF3,RFC4,EIF4E3,SLC38A1,POLA1,GDPD1,TCEB3,NXN,HIST1H2BL,TRIM37,GZF1,RPA1,EXO1,EHMT2,EEFSEC,HNRNPH3,CASS4,BRCC3,BRD9,PTPN14,USP15 |
| 1.631e-02 | -4.12 | GSE13306_TREG_VS_TCONV_DN | MSigDB lists | GSE13306_TREG_VS_TCONV_DN | 183 | 34 | 17758 | 2279 |
TCF3,IKBIP,ST3GAL6,PARN,CUTC,ZNF804A,DCTPP1,ENTPD5,HIRIP3,ANP32B,TSPAN14,CDK6,FADS1,RFC4,AP4S1,HARS,RAPGEF4,PCMT1,ADSL,TBRG4,HSH2D,R3HDM2,MBNL2,PIK3CB,ZNF251,GNG2,YIF1A,LSS,DAGLB,SRD5A3,DUSP19,FNTB,FKBP5,TBL1X |
| 1.632e-02 | -4.12 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | 196 | 36 | 17758 | 2279 |
TCF3,LAGE3,MED13L,GAS6,FAM13A,GBF1,PABPC4,ACD,PMAIP1,ATXN2,PRMT3,TOMM34,ACADS,RFC4,STAG1,CPOX,TPM4,PSMG1,MCM2,MEN1,ODC1,CPT1A,PLCB1,ST3GAL5,TIMM44,RANBP2,SRRD,TRAP1,FDPS,ACP1,SCARB1,IQSEC2,KIF1B,ZBTB24,SLC43A1,NIT1 |
| 1.636e-02 | -4.11 | S1 | smart domains | SM00316 | 12 | 5 | 9131 | 1249 |
EIF2S1,EXOSC2,SRBD1,SUPT6H,PDCD11 |
| 1.636e-02 | -4.11 | JAB_MPN | smart domains | SM00232 | 12 | 5 | 9131 | 1249 |
BRCC3,COPS6,STAMBP,COPS5,EIF3H |
| 1.636e-02 | -4.11 | Cebpb (CCAAT/enhancer binding protein (C/EBP), beta) | protein interactions | 24253 | 49 | 13 | 16036 | 2270 |
TERF2IP,BAZ1A,RFC3,SMARCC1,TFCP2,RFX1,SMARCA4,SSBP1,HLTF,POLE3,NR2F2,DDX49,SMARCB1 |
| 1.636e-02 | -4.11 | HSPBP1 (HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1) | protein interactions | 23640 | 49 | 13 | 16036 | 2270 |
GARS,P3H1,ASNS,SURF2,ALAD,HSPA5,GPN1,LRSAM1,NMD3,HSPA1A,HSPA1B,TOM1L1,LPP |
| 1.636e-02 | -4.11 | BRD7 (bromodomain containing 7) | protein interactions | 29117 | 49 | 13 | 16036 | 2270 |
LAMA4,CHD7,DPF3,SMARCC1,BTBD2,ARID2,RBFOX2,MYC,SMARCA4,POU2F1,GTF3C3,BRCA1,BHLHE40 |
| 1.636e-02 | -4.11 | GTF2E1 (general transcription factor IIE subunit 1) | protein interactions | 2960 | 49 | 13 | 16036 | 2270 |
TTC1,SARS,GTF2A1,TAF1,HARS,XPO5,GTF2H1,TRIM15,ATF7IP,BRCA1,POLR2A,SH3GL1,SRPK2 |
| 1.636e-02 | -4.11 | ARPC4 (actin related protein 2/3 complex subunit 4) | protein interactions | 10093 | 49 | 13 | 16036 | 2270 |
METTL1,FN1,ACTR3,RNF2,RNF130,ACTR3B,BAG1,PRKACB,SH3GL1,RPA1,ARPC3,TOM1L1,LPP |
| 1.636e-02 | -4.11 | PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4) | protein interactions | 5303 | 34 | 10 | 16036 | 2270 |
DYNC1H1,SRPRB,CSNK2A1,SHMT2,MARS,FBL,PNMA1,RTFDC1,SPTAN1,TIMM44 |
| 1.636e-02 | -4.11 | NOC4L (nucleolar complex associated 4 homolog) | protein interactions | 79050 | 34 | 10 | 16036 | 2270 |
PES1,NIFK,DNAJA3,ARL6IP5,SIRT7,VIM,ZNF148,BHLHE40,DKC1,NOP58 |
| 1.636e-02 | -4.11 | POLDIP3 (polymerase (DNA-directed), delta interacting protein 3) | protein interactions | 84271 | 34 | 10 | 16036 | 2270 |
BANP,CUL7,KPNA3,SIRT7,USP20,RNF2,RPS6KB1,PNMA1,TERF2,RPS6KB2 |
| 1.636e-02 | -4.11 | STX8 (syntaxin 8) | protein interactions | 9482 | 34 | 10 | 16036 | 2270 |
VPS18,SRPRB,NSF,STX1A,STX18,HECTD3,DTNBP1,VTI1A,NAPA,CEP170 |
| 1.637e-02 | -4.11 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 71 | 16 | 17758 | 2279 |
USE1,EFNB2,HMGA2,GLTSCR2,WLS,ID2,DSP,DDIT4,CFD,PAM,MED24,ME1,CLU,ITGB4,IGBP1,PERP |
| 1.637e-02 | -4.11 | GGGGCCC,MIR-296 | MSigDB lists | GGGGCCC,MIR-296 | 71 | 16 | 17758 | 2279 |
DBN1,TRPM2,SYNGAP1,SMG7,ATG2B,ONECUT2,FOXP1,CTIF,CACNB1,SLC30A3,GPC2,LARGE,IQSEC2,IPO11,LYPLA2,LRRC41 |
| 1.637e-02 | -4.11 | PKK | interpro domains | IPR022165 | 2 | 2 | 18293 | 2341 |
STK10,SLK |
| 1.637e-02 | -4.11 | DUF1387 | interpro domains | IPR009816 | 2 | 2 | 18293 | 2341 |
SPATS2,SPATS2L |
| 1.637e-02 | -4.11 | Tex-like_dom | interpro domains | IPR023323 | 2 | 2 | 18293 | 2341 |
SRBD1,SUPT6H |
| 1.637e-02 | -4.11 | NOP5_N | interpro domains | IPR012974 | 2 | 2 | 18293 | 2341 |
NOP58,NOP56 |
| 1.637e-02 | -4.11 | His-tRNA-ligase | interpro domains | IPR015807 | 2 | 2 | 18293 | 2341 |
HARS2,HARS |
| 1.637e-02 | -4.11 | SNAP-25 | interpro domains | IPR000928 | 2 | 2 | 18293 | 2341 |
SNAP25,SNAP23 |
| 1.637e-02 | -4.11 | Ski2 | interpro domains | IPR016438 | 2 | 2 | 18293 | 2341 |
SKIV2L,SKIV2L2 |
| 1.637e-02 | -4.11 | Cdc42_binding_dom-like | interpro domains | IPR015116 | 2 | 2 | 18293 | 2341 |
TNK2,ERRFI1 |
| 1.637e-02 | -4.11 | DUF1866 | interpro domains | IPR015047 | 2 | 2 | 18293 | 2341 |
SYNJ2,SYNJ1 |
| 1.637e-02 | -4.11 | N-CoR_GPS2_interact | interpro domains | IPR031557 | 2 | 2 | 18293 | 2341 |
NCOR2,NCOR1 |
| 1.637e-02 | -4.11 | G_Bms1/Tsr1_dom | interpro domains | IPR030387 | 2 | 2 | 18293 | 2341 |
BMS1,TSR1 |
| 1.637e-02 | -4.11 | Ala_tRNA_ligase_euk/bac | interpro domains | IPR023033 | 2 | 2 | 18293 | 2341 |
AARS,AARS2 |
| 1.637e-02 | -4.11 | Ribosomal_S6_kinase | interpro domains | IPR016238 | 2 | 2 | 18293 | 2341 |
RPS6KB1,RPS6KB2 |
| 1.637e-02 | -4.11 | Ala-tRNA-lgiase_IIc | interpro domains | IPR002318 | 2 | 2 | 18293 | 2341 |
AARS,AARS2 |
| 1.637e-02 | -4.11 | Sec15 | interpro domains | IPR007225 | 2 | 2 | 18293 | 2341 |
EXOC6B,EXOC6 |
| 1.637e-02 | -4.11 | Arg-tRNA-synth_N | interpro domains | IPR005148 | 2 | 2 | 18293 | 2341 |
RARS,RARS2 |
| 1.637e-02 | -4.11 | MoaB/Mog_dom | interpro domains | IPR001453 | 2 | 2 | 18293 | 2341 |
FLAD1,GPHN |
| 1.637e-02 | -4.11 | GPCR_2_CD97 | interpro domains | IPR003056 | 2 | 2 | 18293 | 2341 |
ADGRE5,ADGRE2 |
| 1.637e-02 | -4.11 | BAF250/Osa | interpro domains | IPR021906 | 2 | 2 | 18293 | 2341 |
ARID1A,ARID1B |
| 1.637e-02 | -4.11 | DUF3697_Uba2 | interpro domains | IPR022166 | 2 | 2 | 18293 | 2341 |
UBAP2,UBAP2L |
| 1.637e-02 | -4.11 | INSIG_fam | interpro domains | IPR025929 | 2 | 2 | 18293 | 2341 |
INSIG2,INSIG1 |
| 1.637e-02 | -4.11 | MeTrfase_TRM5/TYW2 | interpro domains | IPR030382 | 2 | 2 | 18293 | 2341 |
TRMT5,TRMT12 |
| 1.637e-02 | -4.11 | Spt5_C_dom | interpro domains | IPR024945 | 2 | 2 | 18293 | 2341 |
SUPT5H,SRRM2 |
| 1.637e-02 | -4.11 | Formate_THF_ligase | interpro domains | IPR000559 | 2 | 2 | 18293 | 2341 |
MTHFD1L,MTHFD1 |
| 1.637e-02 | -4.11 | RIO_kinase | interpro domains | IPR000687 | 2 | 2 | 18293 | 2341 |
RIOK1,RIOK3 |
| 1.637e-02 | -4.11 | Ala-tRNA-ligase_IIc_anticod-bd | interpro domains | IPR018162 | 2 | 2 | 18293 | 2341 |
AARS,AARS2 |
| 1.637e-02 | -4.11 | L28e/Mak16 | interpro domains | IPR029004 | 2 | 2 | 18293 | 2341 |
RPL28,MAK16 |
| 1.637e-02 | -4.11 | Ribosomal_S27_mit | interpro domains | IPR019266 | 2 | 2 | 18293 | 2341 |
PTCD2,MRPS27 |
| 1.637e-02 | -4.11 | ATF7-int | interpro domains | IPR026085 | 2 | 2 | 18293 | 2341 |
ATF7IP,ATF7IP2 |
| 1.637e-02 | -4.11 | Mig-6 | interpro domains | IPR021619 | 2 | 2 | 18293 | 2341 |
TNK2,ERRFI1 |
| 1.637e-02 | -4.11 | MAP3K12_MAP3K13 | interpro domains | IPR017419 | 2 | 2 | 18293 | 2341 |
MAP3K13,MAP3K12 |
| 1.637e-02 | -4.11 | FOXO_KIX-bd | interpro domains | IPR032068 | 2 | 2 | 18293 | 2341 |
FOXO1,FOXO3 |
| 1.637e-02 | -4.11 | Sec3-PIP2_bind | interpro domains | IPR028258 | 2 | 2 | 18293 | 2341 |
EXOC1,STXBP6 |
| 1.637e-02 | -4.11 | Fungal_lipase-like | interpro domains | IPR002921 | 2 | 2 | 18293 | 2341 |
DAGLA,DAGLB |
| 1.637e-02 | -4.11 | Cappuccino | interpro domains | IPR024857 | 2 | 2 | 18293 | 2341 |
BCAS4,BLOC1S4 |
| 1.637e-02 | -4.11 | GCV_H | interpro domains | IPR002930 | 2 | 2 | 18293 | 2341 |
FAM206A,GCSH |
| 1.637e-02 | -4.11 | RNF111_N | interpro domains | IPR029306 | 2 | 2 | 18293 | 2341 |
RNF111,C18orf25 |
| 1.637e-02 | -4.11 | Ski2_C | interpro domains | IPR012961 | 2 | 2 | 18293 | 2341 |
SKIV2L,SKIV2L2 |
| 1.637e-02 | -4.11 | rRNA_proc-arch_dom | interpro domains | IPR025696 | 2 | 2 | 18293 | 2341 |
SKIV2L,SKIV2L2 |
| 1.637e-02 | -4.11 | Gly-tRNA_synthase/POLG2 | interpro domains | IPR027031 | 2 | 2 | 18293 | 2341 |
GARS,POLG2 |
| 1.637e-02 | -4.11 | AARP2CN | interpro domains | IPR012948 | 2 | 2 | 18293 | 2341 |
BMS1,TSR1 |
| 1.637e-02 | -4.11 | DUF1370_TMEM126 | interpro domains | IPR009801 | 2 | 2 | 18293 | 2341 |
TMEM126B,TMEM126A |
| 1.637e-02 | -4.11 | SWAP_N_domain | interpro domains | IPR019147 | 2 | 2 | 18293 | 2341 |
CLASRP,SFSWAP |
| 1.637e-02 | -4.11 | HisRS/HisZ | interpro domains | IPR004516 | 2 | 2 | 18293 | 2341 |
HARS2,HARS |
| 1.637e-02 | -4.11 | BMS1_TSR1_C | interpro domains | IPR007034 | 2 | 2 | 18293 | 2341 |
BMS1,TSR1 |
| 1.637e-02 | -4.11 | Phenylalanyl-tRNA_Synthase | interpro domains | IPR002319 | 2 | 2 | 18293 | 2341 |
FARS2,FARSA |
| 1.637e-02 | -4.11 | Arg-tRNA-ligase | interpro domains | IPR001278 | 2 | 2 | 18293 | 2341 |
RARS,RARS2 |
| 1.637e-02 | -4.11 | Glyco_trans_ALG6/ALG8 | interpro domains | IPR004856 | 2 | 2 | 18293 | 2341 |
ALG6,ALG8 |
| 1.637e-02 | -4.11 | F-actin_binding | interpro domains | IPR015015 | 2 | 2 | 18293 | 2341 |
ABL1,ABL2 |
| 1.637e-02 | -4.11 | CASPR3 | interpro domains | IPR028873 | 2 | 2 | 18293 | 2341 |
CNTNAP3,CNTNAP3B |
| 1.637e-02 | -4.11 | 5'(3')-deoxyribonucleotidase | interpro domains | IPR010708 | 2 | 2 | 18293 | 2341 |
NT5C,NT5M |
| 1.637e-02 | -4.11 | Asn-tRNA-ligase | interpro domains | IPR004522 | 2 | 2 | 18293 | 2341 |
NARS2,NARS |
| 1.637e-02 | -4.11 | TIF_IF2_dom3 | interpro domains | IPR023115 | 2 | 2 | 18293 | 2341 |
EIF5B,MTIF2 |
| 1.637e-02 | -4.11 | Formate_THF_ligase_CS | interpro domains | IPR020628 | 2 | 2 | 18293 | 2341 |
MTHFD1L,MTHFD1 |
| 1.637e-02 | -4.11 | JIP_LZII | interpro domains | IPR032486 | 2 | 2 | 18293 | 2341 |
SPAG9,MAPK8IP3 |
| 1.637e-02 | -4.11 | YqgF/RNaseH-like_dom | interpro domains | IPR006641 | 2 | 2 | 18293 | 2341 |
SRBD1,SUPT6H |
| 1.637e-02 | -4.11 | ATF7IP_BD | interpro domains | IPR031870 | 2 | 2 | 18293 | 2341 |
ATF7IP,ATF7IP2 |
| 1.637e-02 | -4.11 | Trp-tRNA-ligase | interpro domains | IPR002306 | 2 | 2 | 18293 | 2341 |
WARS2,WARS |
| 1.637e-02 | -4.11 | Tyr-tRNA-ligase | interpro domains | IPR002307 | 2 | 2 | 18293 | 2341 |
YARS,YARS2 |
| 1.637e-02 | -4.11 | GREB1 | interpro domains | IPR028422 | 2 | 2 | 18293 | 2341 |
GREB1L,GREB1 |
| 1.641e-02 | -4.11 | Metabolism of lipids and lipoproteins | REACTOME pathways | R-HSA-556833 | 628 | 104 | 8202 | 1117 |
CYP24A1,GGT1,MVK,NPAS2,PRKAB2,LPCAT2,TNFRSF21,PPARGC1B,CERS5,LPCAT3,ARSJ,SYNJ1,LCLAT1,FDX1,LPIN1,DECR1,NRF1,IDI1,SREBF2,FAAH2,LPIN2,ME1,RAN,SLC27A5,MGLL,PRKACB,CARM1,ACSL5,MCEE,SEC24A,ACADS,CHD9,PPARG,GPCPD1,MED27,COL4A3BP,CAV1,MED16,PITPNB,HSD3B7,PLIN2,LSS,INSIG1,PEMT,ABHD3,ARNTL,BDH2,ABCC3,MED20,SCARB1,NCOR2,INSIG2,SEC24D,GPAT3,PIK3R4,MED13L,PLA2G12A,MED18,PIP4K2A,SLC25A20,PI4KB,SEC24C,ACOT11,VAPB,MED24,PTGS1,GLTP,CPNE7,SYNJ2,PNPLA3,COQ3,LPCAT1,HSD17B12,SLC25A1,MBTPS2,FDFT1,HMGCR,FADS1,TEAD1,ELOVL6,PCCA,AGPAT4,TBXAS1,SMARCD3,CPT1A,ANGPTL4,PIK3CB,MMAA,VAC14,NEU1,TRIB3,ACOX1,FDPS,MED15,SRD5A3,SQLE,DPEP1,TBL1X,NCOR1,GPAM,PSAP,DHCR7,MTMR1,PDSS2 |
| 1.645e-02 | -4.11 | UDAYAKUMAR_MED1_TARGETS_UP | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_UP | 132 | 26 | 17758 | 2279 |
GARS,PSAT1,NF1,KLHL23,SLK,CAMSAP2,SLC29A1,UBR5,MBNL1,FDX1,CHAF1A,POLR3G,RDH11,SUB1,ASNS,KDELC1,MAD1L1,SLC16A1,ME1,CNOT6,BRD9,OGG1,TROVE2,CAV2,LONP1,TMPO |
| 1.646e-02 | -4.11 | PROTEIN_AUTOPROCESSING | MSigDB lists | PROTEIN_AUTOPROCESSING | 32 | 9 | 17758 | 2279 |
TTN,CAMKK2,TAF1,MAP3K13,MEX3B,MAP3K12,CDK12,SMG1,STK4 |
| 1.646e-02 | -4.11 | NUCLEAR_BODY | MSigDB lists | NUCLEAR_BODY | 32 | 9 | 17758 | 2279 |
GEMIN5,SRSF2,NSRP1,PRPF31,TFIP11,HIPK2,RPAIN,RPA1,TIMM50 |
| 1.646e-02 | -4.11 | MODULE_278 | MSigDB lists | MODULE_278 | 32 | 9 | 17758 | 2279 |
HERC2,CAD,FBXO21,GART,ASNS,UBE2K,UBR5,UBE2E1,MTHFD1 |
| 1.649e-02 | -4.10 | PEDRIOLI_MIR31_TARGETS_DN | MSigDB lists | PEDRIOLI_MIR31_TARGETS_DN | 384 | 64 | 17758 | 2279 |
MYCBP2,FEM1C,NPAS2,PDK4,CACNA1H,KLHL18,SBF2,TMEM177,HLTF,PPP1R9A,TRIM66,NOS1AP,SBDS,RAET1E,PDZD2,MMP7,FMNL1,SOCS6,RELB,CEP135,PEG10,PPM1K,TRIM14,VPS13B,CHD9,AKAP12,ADAM32,LAMA2,GSTCD,ARMC4,ZFAND3,RHOU,ZNF333,ARL6IP5,CLU,MDN1,NRP1,SPOCK2,ZNF532,LAMTOR3,TGFBR2,CMTM3,ABCA7,CNST,SLC7A11,CACNB2,DCTN4,DSG2,CPNE7,CWF19L2,ANGPT2,COL17A1,SETD2,ARHGEF12,PLCB1,KLF6,SMPDL3B,DSC2,ADAT2,IRAK2,SVIL,RBPJ,ITGB4,MMP16 |
| 1.655e-02 | -4.10 | XU_GH1_AUTOCRINE_TARGETS_UP | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_UP | 229 | 41 | 17758 | 2279 |
ARHGAP26,SARS,NOSTRIN,TMEM212,TRPM2,CYLD,ID1,DBF4,OPHN1,C1orf226,VTI1A,RCAN1,APRT,GRINA,SPATS2L,SSR4,PHGDH,CDC73,EDC3,PHC2,TECTA,ZNF827,PRKD3,ABCA12,PEG10,MTHFD2L,PPA1,MAML3,LGALS1,ST6GALNAC3,HIST1H2BL,MARCH6,CASC1,UBE2E1,SNCA,TOM1L2,NSMCE2,CSRNP1,SNX24,ADK,SLC43A1 |
| 1.656e-02 | -4.10 | Ribosomal_S5_D2-typ_fold_subgr | interpro domains | IPR014721 | 22 | 7 | 18293 | 2341 |
PMS1,MVK,MLH1,GALK2,RPS16,GFM2,LONP1 |
| 1.658e-02 | -4.10 | pteridine-containing compound biosynthetic process | biological process | GO:0042559 | 17 | 6 | 16441 | 2138 |
MTHFD1L,MTHFD2,GART,MTHFD2L,ATIC,MTHFD1 |
| 1.658e-02 | -4.10 | oocyte maturation | biological process | GO:0001556 | 17 | 6 | 16441 | 2138 |
KIAA0196,BRCA2,PABPC1L,FOXO3,TRIP13,PDE3A |
| 1.658e-02 | -4.10 | negative regulation of transcription regulatory region DNA binding | biological process | GO:2000678 | 17 | 6 | 16441 | 2138 |
ZNF675,MSX2,ID1,MSX1,MAD2L2,DDIT3 |
| 1.659e-02 | -4.10 | COPS4 (COP9 signalosome subunit 4) | protein interactions | 51138 | 81 | 19 | 16036 | 2270 |
FBXO17,FBXW4,CUL4A,BTBD2,KLHL18,CSNK2A1,TOR1AIP2,ENAH,UBC,COPS4,COPS3,COPS5,IKBKB,CUL2,CCDC85B,COPS7B,COPS6,PRMT5,PTPN14 |
| 1.660e-02 | -4.10 | JIANG_HYPOXIA_CANCER | MSigDB lists | JIANG_HYPOXIA_CANCER | 77 | 17 | 17758 | 2279 |
FBXO17,FN1,LIN28B,PRDX6,ATP6V1A,FERMT2,SERP1,ISG15,ARPC3,DDX3X,LUC7L3,SUCLG2,VAPB,PRMT5,BRD9,CAV2,AUP1 |
| 1.663e-02 | -4.10 | SAP30BP (SAP30 binding protein) | protein interactions | 29115 | 44 | 12 | 16036 | 2270 |
DYNC1H1,FLNC,MLX,TFIP11,FRA10AC1,CSNK2A1,SHMT2,FUS,SUPT5H,TERF2,SAP30,SNCA |
| 1.663e-02 | -4.10 | CREB3 (cAMP responsive element binding protein 3) | protein interactions | 10488 | 44 | 12 | 16036 | 2270 |
MALL,DECR1,TTLL5,ATF4,STX8,COPS5,SQLE,SHMT2,RABAC1,HCFC2,C18orf25,DDIT3 |
| 1.666e-02 | -4.09 | THOC2 (THO complex 2) | protein interactions | 57187 | 39 | 11 | 16036 | 2270 |
TTC1,USP7,THOC5,CUL7,SIRT7,WBSCR22,VIM,RNF2,TPM1,VPS53,RPA1 |
| 1.666e-02 | -4.09 | FYRN | prosite domains | PS51542 | 5 | 3 | 11866 | 1504 |
KMT2D,KMT2C,KMT2A |
| 1.666e-02 | -4.09 | DDT | prosite domains | PS50827 | 5 | 3 | 11866 | 1504 |
BAZ1A,BAZ2B,BAZ2A |
| 1.666e-02 | -4.09 | HIS_KIN | prosite domains | PS50109 | 5 | 3 | 11866 | 1504 |
BCKDK,PDK1,PDK4 |
| 1.666e-02 | -4.09 | FYRC | prosite domains | PS51543 | 5 | 3 | 11866 | 1504 |
KMT2D,KMT2C,KMT2A |
| 1.666e-02 | -4.09 | AWS | prosite domains | PS51215 | 5 | 3 | 11866 | 1504 |
NSD1,ASH1L,SETD2 |
| 1.668e-02 | -4.09 | upper_aerodigestive_tract-head_neck-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma | 22 | 7 | 17775 | 2278 |
ABL1,SRSF2,BRAF,NRAS,KMT2C,MET,NF1 |
| 1.668e-02 | -4.09 | V$TCF1P_Q6 | MSigDB lists | V$TCF1P_Q6 | 249 | 44 | 17758 | 2279 |
TNNC1,ARHGAP26,C16orf52,NECAP1,DPM3,LCLAT1,PABPC4,NRF1,PI4KB,UBR1,INTS7,UCHL5,GPR87,WAC,GLTP,ZMYM2,C12orf4,ZNF646,ZCCHC14,SIK3,FGF9,PPARG,MTIF2,TLE3,ZNF654,R3HDM1,RANGAP1,POLR2A,PRPF40B,NAP1L5,SPAG9,SLC30A3,GATA6,LMBR1L,ADNP,HIF1A,PER1,TBX3,BCAS3,ATM,FIP1L1,TSPAN5,TROVE2,C18orf25 |
| 1.671e-02 | -4.09 | BURTON_ADIPOGENESIS_9 | MSigDB lists | BURTON_ADIPOGENESIS_9 | 89 | 19 | 17758 | 2279 |
FADS1,EGR1,SKAP2,JUP,TSPYL4,CDK4,ID2,AKAP12,FERMT2,TOR1AIP2,SIRT2,GALK2,ANXA1,DDAH2,ASAP1,KLF4,EXOC4,NDRG4,TPM1 |
| 1.671e-02 | -4.09 | Mitochondrial biogenesis | REACTOME pathways | R-HSA-1592230 | 51 | 13 | 8202 | 1117 |
NRF1,CHD9,C10orf2,PRKAB2,PPARGC1B,SMARCD3,TBL1X,SSBP1,MEF2D,NCOR1,POLG2,CARM1,MEF2C |
| 1.672e-02 | -4.09 | head_neck | COSMIC cancer mutations | head_neck | 16165 | 2099 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,THAP4,LETM2,MAD1L1,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SGSM3,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,MCM9,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,CEP170,METTL2B,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,MAGI1,USP15,CTU2,FOXO1,LAMTOR3,FAN1,ZIC2,C1orf52,MBD2,NDRG4,VAPB,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,MTR,SLC26A11,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PABPC1L,HNRNPA3,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,AGPAT4,ADSL,PACS1,BMS1,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,C10orf76,RBM28,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,DNAH17,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,NFASC,ZNF18,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,BZW2,IQGAP2,FAM50A,ZNF561,ANXA7,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,CENPP,ZRANB3,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,TNFRSF21,ADAMTS6,GIPR,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,LIN28B,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,DCBLD2,CPED1,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,TSHZ1,WDFY3,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,OGG1,TRIM14,PRKACB,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,UBAP2,MYBBP1A,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,PRKCH,GART,TANK,KDELC1,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,CUL2,NCBP2,ZRANB2,MBD6,MMP16,SLC16A10,HRH1,GGT1,PTP4A1,ARHGAP26,ADAM19,CNTNAP3,MKS1,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,RNMT,KLHL23,UPP1,C11orf80,NFIA,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,SAMD3,RABEPK,NOM1,MYB,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,DYNC1H1,IRS1,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,INTS12,C16orf58,MSH4,PEG10,TRMT12,KIAA1549,LYST,ZNF480,PI4KAP2,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,DSP,NUDT15,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,TRIML2,ANKRD11,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,LAMA2,KRTCAP2,KCNH2,LSG1,BSN,CXADR,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,MAPK8IP3,SMAD7,NKD2,ARID1B,SPIRE1,RNFT2,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TNKS1BP1,DENND3,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,NRF1,ZNF608,ANKRD13A,JAG1,IDI1,GRIN2C,FGGY,AHCYL1,IPO11,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,INTS9,ATG7,MED20,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,C12orf4,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,DSC2,CSRNP1,TMEM219,USP20,FNTB,RBM26,RBPJ,C6orf223,KIF1B,XPO6,LMBRD2,LUZP1,GYG1,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,DDX60,SON,DENND4A,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,NMD3,SPOCK2,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,SCAF1,USPL1,LDOC1L,NOVA2,MFAP2,CNOT4,RTFDC1,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,CORO6,PTPRG,RING1,IGSF1,FLNB,NOP56,DECR1,ARMC6,PPID,LPIN2,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,YARS,HCFC2,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,COTL1,PITPNB,ST3GAL5,CC2D1B,FAM114A2,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,STXBP6,VTA1,PCSK7,ELL,HVCN1,ZNF354A,ISPD,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,FEZ2,DLL4,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,IGF2BP2,ATF7IP,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,ZNF821,FGF2,KDM5A,PSPC1,ASAP3,SCFD2,PDE2A,EIF5B,NAALADL2,ZNF221,WDR35,VPS37B,ANKRD30BL,POLR1C,NIT1,ZSWIM6,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,PMAIP1,NSRP1,FAAH2,RASSF3,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,PTPRM,WLS,RFX2,PACRGL,AKAP12,MCL1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,CACNB2,MCM5,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,COL17A1,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,VPS13C,TASP1,LRP1B,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,ABCA12,BCAS2,ZKSCAN1,FMNL1,GSTA4,CEP63,PERP,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,MBNL1,POM121,TADA3,KRI1,GATC,PVRL3,SOX6,ULBP1,DIS3L2,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,SLC3A2,ZNF124,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,KIF16B,PEX1,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,NARS,THSD4,BTBD11,SMAD3,RANBP2,SIX5,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,MAP1S,C14orf159,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,SET,MSH3,EIF2S1,ITGB4,MIPOL1,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,UBR5,AARS,MGA,PAK1IP1,VPS52,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,TCEB3,CUX1,SEMA3F,MAK16,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,DAGLA,KIDINS220,SRRD,NSF,PMEPA1,UBAP1,ZZEF1,RIOK3,PEX13,RTTN,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SERPINH1,PNPLA4,KMT2A,NAA35,MPP6,PDK1,MTIF2,SFXN4,DLG4,MED16,GALK2,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,TCF3,MRI1,NFX1,RTN4,MON2,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,ZNF804A,ANAPC1,RAP1A,LONRF2,THADA,YLPM1,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,COPS6,ZNF397,TNRC6A,SLC12A7,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,CCDC112,SEMA3D,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,SH2D3A,SULT1C2,DBF4,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.673e-02 | -4.09 | - | gene3d domains | 2.30.29.40 | 8 | 4 | 9988 | 1398 |
NBEA,NBEAL1,WDFY3,LYST |
| 1.675e-02 | -4.09 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1940 | 279 | 17775 | 2278 |
ARHGAP26,POLB,THOC5,PRKAB2,HLTF,PRKCA,NUP160,LPAR3,UBR5,SKI,GIPR,EXOC1,PMAIP1,MAD1L1,KDM5C,CDK6,ZNF646,CCDC57,NRAS,NOL8,C11orf80,CUX1,SLC9A5,SH3GL1,SPOP,BRCA2,RAD18,SH3RF1,DIRAS1,RUNX1,CCNB1IP1,NRP1,FIP1L1,ZNF598,LPP,MEF2C,CARS,CELSR1,TRIO,DLGAP4,PIK3R4,PDCD7,TGFBR2,CDC73,PRKCE,UBE3A,USPL1,ATIC,MYC,SAMD13,CCDC88C,FMNL2,GATAD2B,PEA15,SIK3,GTF2H3,COL17A1,PRDM16,RAP1B,RYR2,USP10,PTPN12,ARID1A,TRIM37,USP46,IRS1,DYNC1H1,VPS13C,ZCCHC6,SQLE,MAP2K4,SPRED2,ABCA3,DDR2,FOSL2,LTB4R,FLNB,SHC1,KDM2A,ZKSCAN1,UCHL5,SOCS6,TTC3,MSH4,KMT2A,TRMT12,CDK12,LYST,PMS1,ZCCHC14,KMT2D,BRD4,PDK1,STAMBP,PCNXL2,MARCH6,MEF2D,SLC35D1,STK10,ERC1,FGFR1,BAZ1A,SMARCC1,ACP1,RPS6KB1,TRAF3,FUS,BRCC3,TRIM36,BRAF,XPC,TTC27,TCF3,ATG2B,MLH1,TGFB2,FOXO3,FAM8A1,MAD2L2,NEDD4,ABL1,LTN1,FBXL19,SPTAN1,FGF9,PXN,APEX1,FZD3,C9orf153,KLF6,HERC1,ATM,BMP4,RABEP1,DDIT3,STK4,FAM227A,ATRX,NF1,GPBP1L1,FANCD2,HECTD3,CSNK2A1,RNF43,SEC16A,BIRC2,MAP2K3,SMARCB1,WNT2B,ABL2,RAP1A,YLPM1,JAZF1,NCKIPSD,ANAPC11,XRCC2,RELB,JOSD1,RAN,ZMYM2,ETV1,OGG1,PRKACB,LONP1,CDC37,DBN1,RBCK1,PPARG,CDK4,KSR2,BRCA1,CAV1,KMT2C,SGK2,MLLT10,RHOU,LSS,TCF7L1,SUFU,PER1,SOCS4,CTAGE5,RAD51B,TNFRSF1A,ADAM9,COPS6,MAGI1,USP15,FBXO45,FN1,FOXO1,MAPK8IP3,MEX3A,LAMTOR3,PCSK7,ARID1B,ELL,GTF2H1,WNT16,MSI2,RANBP6,PDE4A,USP49,TLE3,OBSCN,LIG4,TCF7L2,SPAG9,PALB2,SDCCAG8,PPP1R12B,DDX10,PRKAR2A,USP7,TCF12,DLL4,CYLD,ARID2,NTSR1,PBX1,RIPK1,PPP2R2A,SMARCA4,RADIL,PLXNB1,SBDS,JAG1,SOCS1,FSIP2,IKBKB,RNF2,ITGAX,MET,CASP10,MAML3,KIRREL2,PARP2,SFSWAP,NUP214,USP36,EIF3H,BTBD11,EXO1,RANBP2,RBBP8,COPS5,NFRKB,SEPT5,USP11,MUTYH,SMG1,UNC13D,KLHL24,BCKDK,SEMA3E,CSNK1A1,ANXA7,CTNNBL1,TTC17,TOP1,RPS6KB2,ADAMTSL3,FGF2,KDM5A,TEX14,RAP1GDS1,ARHGEF12,MEN1,PIK3CB,ZRANB3,DKK1,CACNB1,SET,MSH3,DNAJC12,USP20,RBPJ,NFKBIB,KIF1B |
| 1.675e-02 | -4.09 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1940 | 279 | 17775 | 2278 |
ARHGAP26,POLB,THOC5,PRKAB2,HLTF,PRKCA,NUP160,LPAR3,UBR5,SKI,GIPR,EXOC1,PMAIP1,MAD1L1,KDM5C,CDK6,ZNF646,CCDC57,NRAS,NOL8,C11orf80,CUX1,SLC9A5,SH3GL1,SPOP,BRCA2,RAD18,SH3RF1,DIRAS1,RUNX1,CCNB1IP1,NRP1,FIP1L1,ZNF598,LPP,MEF2C,CARS,CELSR1,TRIO,DLGAP4,PIK3R4,PDCD7,TGFBR2,CDC73,PRKCE,UBE3A,USPL1,ATIC,MYC,SAMD13,CCDC88C,FMNL2,GATAD2B,PEA15,SIK3,GTF2H3,COL17A1,PRDM16,RAP1B,RYR2,USP10,PTPN12,ARID1A,TRIM37,USP46,IRS1,DYNC1H1,VPS13C,ZCCHC6,SQLE,MAP2K4,SPRED2,ABCA3,DDR2,FOSL2,LTB4R,FLNB,SHC1,KDM2A,ZKSCAN1,UCHL5,SOCS6,TTC3,MSH4,KMT2A,TRMT12,CDK12,LYST,PMS1,ZCCHC14,KMT2D,BRD4,PDK1,STAMBP,PCNXL2,MARCH6,MEF2D,SLC35D1,STK10,ERC1,FGFR1,BAZ1A,SMARCC1,ACP1,RPS6KB1,TRAF3,FUS,BRCC3,TRIM36,BRAF,XPC,TTC27,TCF3,ATG2B,MLH1,TGFB2,FOXO3,FAM8A1,MAD2L2,NEDD4,ABL1,LTN1,FBXL19,SPTAN1,FGF9,PXN,APEX1,FZD3,C9orf153,KLF6,HERC1,ATM,BMP4,RABEP1,DDIT3,STK4,FAM227A,ATRX,NF1,GPBP1L1,FANCD2,HECTD3,CSNK2A1,RNF43,SEC16A,BIRC2,MAP2K3,SMARCB1,WNT2B,ABL2,RAP1A,YLPM1,JAZF1,NCKIPSD,ANAPC11,XRCC2,RELB,JOSD1,RAN,ZMYM2,ETV1,OGG1,PRKACB,LONP1,CDC37,DBN1,RBCK1,PPARG,CDK4,KSR2,BRCA1,CAV1,KMT2C,SGK2,MLLT10,RHOU,LSS,TCF7L1,SUFU,PER1,SOCS4,CTAGE5,RAD51B,TNFRSF1A,ADAM9,COPS6,MAGI1,USP15,FBXO45,FN1,FOXO1,MAPK8IP3,MEX3A,LAMTOR3,PCSK7,ARID1B,ELL,GTF2H1,WNT16,MSI2,RANBP6,PDE4A,USP49,TLE3,OBSCN,LIG4,TCF7L2,SPAG9,PALB2,SDCCAG8,PPP1R12B,DDX10,PRKAR2A,USP7,TCF12,DLL4,CYLD,ARID2,NTSR1,PBX1,RIPK1,PPP2R2A,SMARCA4,RADIL,PLXNB1,SBDS,JAG1,SOCS1,FSIP2,IKBKB,RNF2,ITGAX,MET,CASP10,MAML3,KIRREL2,PARP2,SFSWAP,NUP214,USP36,EIF3H,BTBD11,EXO1,RANBP2,RBBP8,COPS5,NFRKB,SEPT5,USP11,MUTYH,SMG1,UNC13D,KLHL24,BCKDK,SEMA3E,CSNK1A1,ANXA7,CTNNBL1,TTC17,TOP1,RPS6KB2,ADAMTSL3,FGF2,KDM5A,TEX14,RAP1GDS1,ARHGEF12,MEN1,PIK3CB,ZRANB3,DKK1,CACNB1,SET,MSH3,DNAJC12,USP20,RBPJ,NFKBIB,KIF1B |
| 1.676e-02 | -4.09 | ZnF_C2H2 | smart domains | SM00355 | 800 | 130 | 9131 | 1249 |
ZNF292,ZNF76,ZNF107,ZNF44,ZNF37A,ZNF804A,ZFHX3,IKZF5,JAZF1,HKR1,ZEB1,WIZ,ZNF148,ZNF85,ZNF3,ZNF646,ZBTB17,DPF3,AEBP2,ZNF124,ZNF195,ZNF680,ZNF414,ZSCAN2,ZNF91,ZNF197,GZF1,ZNF622,ZNF266,RBSN,ZNF81,HIC2,ZNF397,ZMAT3,ZNF598,ZNF532,EGR1,ZHX3,DPF2,ZIC2,RLF,RBM20,ZNF358,ZNF354A,ZNF586,ZNF326,ZNF518B,ZNF629,ZNF675,ZNF234,RREB1,ZNF587,PRDM16,ZFP14,ZNF512B,PRDM1,ZNF850,ZNF655,ZNF425,ATXN7,ZBTB12,ZNF160,ZNF430,ZFP90,ZFHX2,ZBTB24,RNF114,ZNF254,ZNF706,ZNF516,TRERF1,ARID2,ZBTB37,ZNF83,ZNF709,ZMAT2,EEA1,ZNF121,ZSCAN5A,ZNF608,ZBTB21,ZNF827,ZKSCAN1,ZNF142,ZFP37,ZNF460,PRMT3,AKAP8L,ZNF480,ZNF251,ZBTB25,IKZF4,ADNP,ZNF333,KLF4,ZNF557,ZNF236,ZNF436,ZNF18,ZBTB11,ZNF589,ZNF507,ZNF786,ZNF280C,SF3A3,MYNN,ZNF346,ZNF691,FOXP1,POGZ,ZNF594,ZNF239,ZNF483,ZNF561,ZNF710,TSHZ1,ZNF821,ZNF654,DHX34,ZNF324B,APTX,ZNF467,KLF6,ZNF407,ZNF221,ZNF708,ZFP62,ZNF155,RNF138,ZNF32 |
| 1.677e-02 | -4.09 | V$SREBP1_01 | MSigDB lists | V$SREBP1_01 | 164 | 31 | 17758 | 2279 |
KLHL24,BDNF,ATF4,APEX1,ANAPC13,SUPT6H,ATP6V1A,SETD2,TOP3A,AKAP12,ATF7IP,GPNMB,MCM2,AARS,GIGYF2,FAM192A,PRKCE,RSPRY1,CAMK2D,ATG3,HSPBAP1,SET,DCTN4,HK2,GTF2H1,JOSD1,CHD2,DLX2,CEP63,EME1,ATP6V0D1 |
| 1.680e-02 | -4.09 | paranodal junction | cellular component | GO:0033010 | 5 | 3 | 17570 | 2233 |
NFASC,SIRT2,MARVELD2 |
| 1.680e-02 | -4.09 | MRNA_BINDING | MSigDB lists | MRNA_BINDING | 22 | 7 | 17758 | 2279 |
PURB,ZFP36L1,AUH,PARN,PABPC1,SERBP1,PABPC4 |
| 1.680e-02 | -4.09 | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN | MSigDB lists | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN | 22 | 7 | 17758 | 2279 |
ID2,CAT,BDNF,MET,KRT7,JUP,MGST1 |
| 1.680e-02 | -4.09 | CHIBA_RESPONSE_TO_TSA_DN | MSigDB lists | CHIBA_RESPONSE_TO_TSA_DN | 22 | 7 | 17758 | 2279 |
ADAM9,PTK2,BRCA2,LAMC1,TGFB2,DSP,TOP1 |
| 1.682e-02 | -4.09 | HSP90AB1 (heat shock protein 90kDa alpha (cytosolic), class B member 1) | protein interactions | 3326 | 269 | 51 | 16036 | 2270 |
MCM6,CUL7,BRAF,CUL4A,FN1,ACTG1,MYH9,CSNK2A1,IP6K2,STK33,SSR4,AARS,HSPA1A,PRKCE,RPS16,SHC1,ACD,COPS4,PPID,MCM5,IKBKB,ARHGAP1,MAP3K14,TOMM34,PRKACB,CDC37,RPS6KB2,SPTAN1,MTHFD1,TUBA1A,PSAT1,DDX24,NPM3,CDK4,HSPA5,LDHA,MCM2,METTL22,EIF3H,ISG15,UBC,STOML2,HIF1A,CDK9,CAMKMT,CUL2,GPN1,FKBP5,FUS,SMYD3,AGO3 |
| 1.688e-02 | -4.08 | DYNC1H1 (dynein, cytoplasmic 1, heavy chain 1) | protein interactions | 1778 | 109 | 24 | 16036 | 2270 |
FLNC,USP7,TNIK,CUL7,FN1,PAFAH1B1,SIRT7,AKAP12,BRCA1,IKBKAP,TNKS1BP1,SAP30BP,SNCA,NUP133,MYC,COPS5,RNF2,FUS,PRMT5,YARS,BMI1,LONP1,SERBP1,SF3A1 |
| 1.690e-02 | -4.08 | LEE_RECENT_THYMIC_EMIGRANT | MSigDB lists | LEE_RECENT_THYMIC_EMIGRANT | 203 | 37 | 17758 | 2279 |
HERC2,SPRED2,AUH,TRIO,ID2,BCOR,IGF2BP3,ZNF827,LYPLAL1,DSG2,FNIP2,YARS,MTHFD2L,N4BP2,MAML3,PRPF19,TIMM8B,AEBP2,SKAP2,ERICH1,MTHFD1L,SOX4,ISG15,PLCXD2,GNAI1,RHOU,VPS13C,PXDN,PDLIM1,SERF2,MPP7,PMEPA1,MBTD1,RNF138,PEX13,ZAK,LPP |
| 1.690e-02 | -4.08 | GDP-L-fucose biosynthetic process | biological process | GO:0042350 | 2 | 2 | 16441 | 2138 |
GMDS,TSTA3 |
| 1.690e-02 | -4.08 | regulation of serine C-palmitoyltransferase activity | biological process | GO:1904220 | 2 | 2 | 16441 | 2138 |
SERINC5,SERINC1 |
| 1.690e-02 | -4.08 | uropod organization | biological process | GO:0032796 | 2 | 2 | 16441 | 2138 |
MYH9,CORO1A |
| 1.690e-02 | -4.08 | lysosomal microautophagy | biological process | GO:0016237 | 2 | 2 | 16441 | 2138 |
ATG9A,ATG7 |
| 1.690e-02 | -4.08 | negative regulation of phospholipase C activity | biological process | GO:1900275 | 2 | 2 | 16441 | 2138 |
ABL1,BICD1 |
| 1.690e-02 | -4.08 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity | biological process | GO:1904217 | 2 | 2 | 16441 | 2138 |
SERINC5,SERINC1 |
| 1.690e-02 | -4.08 | meiotic metaphase I plate congression | biological process | GO:0043060 | 2 | 2 | 16441 | 2138 |
MLH1,BRCA2 |
| 1.690e-02 | -4.08 | positive regulation of RNA export from nucleus | biological process | GO:0046833 | 2 | 2 | 16441 | 2138 |
NCBP2,KHDRBS1 |
| 1.690e-02 | -4.08 | positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity | biological process | GO:1904219 | 2 | 2 | 16441 | 2138 |
SERINC5,SERINC1 |
| 1.690e-02 | -4.08 | positive regulation of serine C-palmitoyltransferase activity | biological process | GO:1904222 | 2 | 2 | 16441 | 2138 |
SERINC5,SERINC1 |
| 1.690e-02 | -4.08 | cellular response to lead ion | biological process | GO:0071284 | 2 | 2 | 16441 | 2138 |
HMBS,ALAD |
| 1.690e-02 | -4.08 | peptidyl-lysine hydroxylation | biological process | GO:0017185 | 2 | 2 | 16441 | 2138 |
PLOD1,JMJD6 |
| 1.690e-02 | -4.08 | peroxisome localization | biological process | GO:0060151 | 2 | 2 | 16441 | 2138 |
PEX13,PEX1 |
| 1.690e-02 | -4.08 | regulation of endocannabinoid signaling pathway | biological process | GO:2000124 | 2 | 2 | 16441 | 2138 |
MGLL,ABHD6 |
| 1.690e-02 | -4.08 | piecemeal microautophagy of nucleus | biological process | GO:0034727 | 2 | 2 | 16441 | 2138 |
ATG9A,ATG7 |
| 1.690e-02 | -4.08 | negative regulation of chemokine (C-X-C motif) ligand 2 production | biological process | GO:2000342 | 2 | 2 | 16441 | 2138 |
MAP2K5,KLF4 |
| 1.690e-02 | -4.08 | regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter | biological process | GO:0072368 | 2 | 2 | 16441 | 2138 |
NCOR1,SREBF2 |
| 1.690e-02 | -4.08 | pre-miRNA export from nucleus | biological process | GO:0035281 | 2 | 2 | 16441 | 2138 |
RAN,XPO5 |
| 1.690e-02 | -4.08 | regulation of histone H3-K79 methylation | biological process | GO:2001160 | 2 | 2 | 16441 | 2138 |
CTR9,WDR61 |
| 1.690e-02 | -4.08 | positive regulation of mineralocorticoid secretion | biological process | GO:2000857 | 2 | 2 | 16441 | 2138 |
BMP6,C1QTNF1 |
| 1.690e-02 | -4.08 | regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | biological process | GO:1901295 | 2 | 2 | 16441 | 2138 |
RBPJ,DKK1 |
| 1.690e-02 | -4.08 | single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0039692 | 2 | 2 | 16441 | 2138 |
SUPT5H,SMARCB1 |
| 1.690e-02 | -4.08 | regulation of SA node cell action potential | biological process | GO:0098907 | 2 | 2 | 16441 | 2138 |
RYR2,ANK2 |
| 1.690e-02 | -4.08 | positive regulation of histone H3-K79 methylation | biological process | GO:2001162 | 2 | 2 | 16441 | 2138 |
CTR9,WDR61 |
| 1.690e-02 | -4.08 | microtubule-based peroxisome localization | biological process | GO:0060152 | 2 | 2 | 16441 | 2138 |
PEX13,PEX1 |
| 1.690e-02 | -4.08 | tryptophanyl-tRNA aminoacylation | biological process | GO:0006436 | 2 | 2 | 16441 | 2138 |
WARS2,WARS |
| 1.690e-02 | -4.08 | regulation of mineralocorticoid secretion | biological process | GO:2000855 | 2 | 2 | 16441 | 2138 |
BMP6,C1QTNF1 |
| 1.690e-02 | -4.08 | AMP catabolic process | biological process | GO:0006196 | 2 | 2 | 16441 | 2138 |
AMPD3,NT5E |
| 1.690e-02 | -4.08 | male germ cell proliferation | biological process | GO:0002176 | 2 | 2 | 16441 | 2138 |
EIF2S2,DMRT1 |
| 1.690e-02 | -4.08 | single-organism membrane invagination | biological process | GO:1902534 | 2 | 2 | 16441 | 2138 |
ATG9A,ATG7 |
| 1.690e-02 | -4.08 | protein localization to M-band | biological process | GO:0036309 | 2 | 2 | 16441 | 2138 |
OBSCN,ANK2 |
| 1.690e-02 | -4.08 | tyrosyl-tRNA aminoacylation | biological process | GO:0006437 | 2 | 2 | 16441 | 2138 |
YARS,YARS2 |
| 1.690e-02 | -4.08 | positive regulation of aldosterone secretion | biological process | GO:2000860 | 2 | 2 | 16441 | 2138 |
BMP6,C1QTNF1 |
| 1.690e-02 | -4.08 | meiotic metaphase plate congression | biological process | GO:0051311 | 2 | 2 | 16441 | 2138 |
MLH1,BRCA2 |
| 1.690e-02 | -4.08 | regulation of mRNA binding | biological process | GO:1902415 | 2 | 2 | 16441 | 2138 |
CDK9,CARM1 |
| 1.690e-02 | -4.08 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol | biological process | GO:1904211 | 2 | 2 | 16441 | 2138 |
HM13,RHBDD1 |
| 1.690e-02 | -4.08 | histidine biosynthetic process | biological process | GO:0000105 | 2 | 2 | 16441 | 2138 |
MTHFD2L,MTHFD1 |
| 1.690e-02 | -4.08 | late nucleophagy | biological process | GO:0044805 | 2 | 2 | 16441 | 2138 |
ATG9A,ATG7 |
| 1.690e-02 | -4.08 | establishment of cell polarity involved in ameboidal cell migration | biological process | GO:0003365 | 2 | 2 | 16441 | 2138 |
AMOTL1,AMOT |
| 1.690e-02 | -4.08 | blood vessel lumenization | biological process | GO:0072554 | 2 | 2 | 16441 | 2138 |
DLL4,RBPJ |
| 1.690e-02 | -4.08 | histone H2A-K119 monoubiquitination | biological process | GO:0036353 | 2 | 2 | 16441 | 2138 |
RNF2,TRIM37 |
| 1.690e-02 | -4.08 | histidyl-tRNA aminoacylation | biological process | GO:0006427 | 2 | 2 | 16441 | 2138 |
HARS2,HARS |
| 1.690e-02 | -4.08 | histone H2B conserved C-terminal lysine deubiquitination | biological process | GO:0035616 | 2 | 2 | 16441 | 2138 |
USP49,USP15 |
| 1.690e-02 | -4.08 | regulation of aldosterone secretion | biological process | GO:2000858 | 2 | 2 | 16441 | 2138 |
BMP6,C1QTNF1 |
| 1.690e-02 | -4.08 | DNA rewinding | biological process | GO:0036292 | 2 | 2 | 16441 | 2138 |
ZRANB3,ANXA1 |
| 1.690e-02 | -4.08 | 'de novo' GDP-L-fucose biosynthetic process | biological process | GO:0042351 | 2 | 2 | 16441 | 2138 |
GMDS,TSTA3 |
| 1.690e-02 | -4.08 | AMP salvage | biological process | GO:0044209 | 2 | 2 | 16441 | 2138 |
APRT,ADK |
| 1.694e-02 | -4.08 | MAYBURD_RESPONSE_TO_L663536_UP | MSigDB lists | MAYBURD_RESPONSE_TO_L663536_UP | 27 | 8 | 17758 | 2279 |
ARHGAP26,GARS,SLC7A11,SLC38A2,SMARCA4,ZNF346,USP11,YARS |
| 1.694e-02 | -4.08 | ATF7IP_BD | pfam domains | PF16788 | 2 | 2 | 16629 | 2165 |
ATF7IP,ATF7IP2 |
| 1.694e-02 | -4.08 | Inhibitor_Mig-6 | pfam domains | PF11555 | 2 | 2 | 16629 | 2165 |
TNK2,ERRFI1 |
| 1.694e-02 | -4.08 | Sec3-PIP2_bind | pfam domains | PF15277 | 2 | 2 | 16629 | 2165 |
EXOC1,STXBP6 |
| 1.694e-02 | -4.08 | RNF111_N | pfam domains | PF15303 | 2 | 2 | 16629 | 2165 |
RNF111,C18orf25 |
| 1.694e-02 | -4.08 | MoCF_biosynth | pfam domains | PF00994 | 2 | 2 | 16629 | 2165 |
FLAD1,GPHN |
| 1.694e-02 | -4.08 | DSHCT | pfam domains | PF08148 | 2 | 2 | 16629 | 2165 |
SKIV2L,SKIV2L2 |
| 1.694e-02 | -4.08 | rRNA_proc-arch | pfam domains | PF13234 | 2 | 2 | 16629 | 2165 |
SKIV2L,SKIV2L2 |
| 1.694e-02 | -4.08 | INSIG | pfam domains | PF07281 | 2 | 2 | 16629 | 2165 |
INSIG2,INSIG1 |
| 1.694e-02 | -4.08 | SNAP-25 | pfam domains | PF00835 | 2 | 2 | 16629 | 2165 |
SNAP25,SNAP23 |
| 1.694e-02 | -4.08 | Lipase_3 | pfam domains | PF01764 | 2 | 2 | 16629 | 2165 |
DAGLA,DAGLB |
| 1.694e-02 | -4.08 | FOXO_KIX_bdg | pfam domains | PF16675 | 2 | 2 | 16629 | 2165 |
FOXO1,FOXO3 |
| 1.694e-02 | -4.08 | DUF3518 | pfam domains | PF12031 | 2 | 2 | 16629 | 2165 |
ARID1A,ARID1B |
| 1.694e-02 | -4.08 | NOP5NT | pfam domains | PF08156 | 2 | 2 | 16629 | 2165 |
NOP58,NOP56 |
| 1.694e-02 | -4.08 | Alg6_Alg8 | pfam domains | PF03155 | 2 | 2 | 16629 | 2165 |
ALG6,ALG8 |
| 1.694e-02 | -4.08 | tRNA-synt_2d | pfam domains | PF01409 | 2 | 2 | 16629 | 2165 |
FARS2,FARSA |
| 1.694e-02 | -4.08 | Ribosomal_L28e | pfam domains | PF01778 | 2 | 2 | 16629 | 2165 |
RPL28,MAK16 |
| 1.694e-02 | -4.08 | MRP-S27 | pfam domains | PF10037 | 2 | 2 | 16629 | 2165 |
PTCD2,MRPS27 |
| 1.694e-02 | -4.08 | DRY_EERY | pfam domains | PF09750 | 2 | 2 | 16629 | 2165 |
CLASRP,SFSWAP |
| 1.694e-02 | -4.08 | AARP2CN | pfam domains | PF08142 | 2 | 2 | 16629 | 2165 |
TSR1,BMS1 |
| 1.694e-02 | -4.08 | DUF3697 | pfam domains | PF12478 | 2 | 2 | 16629 | 2165 |
UBAP2,UBAP2L |
| 1.694e-02 | -4.08 | DUF1387 | pfam domains | PF07139 | 2 | 2 | 16629 | 2165 |
SPATS2,SPATS2L |
| 1.694e-02 | -4.08 | Complex1_LYR_1 | pfam domains | PF13232 | 2 | 2 | 16629 | 2165 |
LYRM4,LYRM2 |
| 1.694e-02 | -4.08 | Met_10 | pfam domains | PF02475 | 2 | 2 | 16629 | 2165 |
TRMT5,TRMT12 |
| 1.694e-02 | -4.08 | Sec15 | pfam domains | PF04091 | 2 | 2 | 16629 | 2165 |
EXOC6B,EXOC6 |
| 1.694e-02 | -4.08 | JIP_LZII | pfam domains | PF16471 | 2 | 2 | 16629 | 2165 |
SPAG9,MAPK8IP3 |
| 1.694e-02 | -4.08 | DUF1866 | pfam domains | PF08952 | 2 | 2 | 16629 | 2165 |
SYNJ2,SYNJ1 |
| 1.694e-02 | -4.08 | GTPase_binding | pfam domains | PF09027 | 2 | 2 | 16629 | 2165 |
TNK2,ERRFI1 |
| 1.694e-02 | -4.08 | tRNA-synt_1d | pfam domains | PF00750 | 2 | 2 | 16629 | 2165 |
RARS,RARS2 |
| 1.694e-02 | -4.08 | GREB1 | pfam domains | PF15782 | 2 | 2 | 16629 | 2165 |
GREB1L,GREB1 |
| 1.694e-02 | -4.08 | DUF1370 | pfam domains | PF07114 | 2 | 2 | 16629 | 2165 |
TMEM126B,TMEM126A |
| 1.694e-02 | -4.08 | GCV_H | pfam domains | PF01597 | 2 | 2 | 16629 | 2165 |
FAM206A,GCSH |
| 1.694e-02 | -4.08 | IF-2 | pfam domains | PF11987 | 2 | 2 | 16629 | 2165 |
EIF5B,MTIF2 |
| 1.694e-02 | -4.08 | NT5C | pfam domains | PF06941 | 2 | 2 | 16629 | 2165 |
NT5C,NT5M |
| 1.694e-02 | -4.08 | RIBIOP_C | pfam domains | PF04950 | 2 | 2 | 16629 | 2165 |
BMS1,TSR1 |
| 1.694e-02 | -4.08 | FTHFS | pfam domains | PF01268 | 2 | 2 | 16629 | 2165 |
MTHFD1L,MTHFD1 |
| 1.694e-02 | -4.08 | GPS2_interact | pfam domains | PF15784 | 2 | 2 | 16629 | 2165 |
NCOR2,NCOR1 |
| 1.694e-02 | -4.08 | PKK | pfam domains | PF12474 | 2 | 2 | 16629 | 2165 |
STK10,SLK |
| 1.694e-02 | -4.08 | F_actin_bind | pfam domains | PF08919 | 2 | 2 | 16629 | 2165 |
ABL1,ABL2 |
| 1.695e-02 | -4.08 | positive regulation of molecular function | biological process | GO:0044093 | 1782 | 261 | 16441 | 2138 |
ARHGAP26,DCP1B,SBF2,CCNL2,PRKCA,LPAR3,AMBRA1,NOS1AP,SKI,GIPR,TOM1L1,S100A10,PMAIP1,RABGAP1L,FXN,TBC1D8,NRAS,C5AR1,DCUN1D5,DENND4A,DDX3X,CCNT1,ARL6IP5,FIS1,DIRAS1,TPM1,NRP1,BMI1,P2RY11,MEF2C,HERC2,EPM2AIP1,IFT57,CDC42EP2,JUP,SLK,TRIO,OPHN1,PIK3R4,CRACR2A,TGFBR2,PDCD5,ABCA7,PRKCE,FKBP1A,CHN1,ASAP1,MYC,ANP32B,MAP3K12,CAV2,TERF2,PEA15,BDNF,SYNGAP1,ARID5B,RAPGEF4,RAP1GAP2,RYR2,ARRDC4,EVI5,PLCB1,TRIM37,SRA1,IRS1,CAT,KIDINS220,HIF1A,CDK9,CNOT6,IQSEC2,ARHGAP10,SGSM3,MAP2K5,DDR2,AGAP6,HSPA1A,TERF2IP,SLX4,SHC1,ACD,TBC1D22A,MMP14,SSBP1,KMT2A,DENND1A,PERP,CASP8AP2,BRD4,ARHGEF10,PREX1,DLG4,MED16,TBC1D16,STK10,ERC1,FGFR1,SNCA,VDR,ARHGAP21,CAMK2D,CDC16,HIPK2,DNAJA3,ANXA2,TBXA2R,XRCC4,HMGA2,SERINC5,BRAF,TCF3,GAS6,TRIM22,MON2,TGFB2,RPS6KA5,PSMF1,ABL1,NPRL2,RGS17,ACAP3,RAPGEFL1,ARHGAP1,NLGN3,MAP3K14,ERRFI1,PLEKHG4,SPTAN1,MBTPS2,FGF9,PXN,PACS1,PTK2,IL6R,UBC,OXSR1,TRIB3,HERC1,APAF1,PSAP,BMP4,PGAM5,RABEP1,DOCK6,ANAPC4,STK4,NF1,PTPRA,PPARGC1B,SIRT2,FAM13A,GIT2,MAP2K3,SMARCB1,ABL2,ANAPC1,RAP1A,ARHGAP18,ANAPC11,ANAPC10,PCOLCE2,RAN,TRIM14,PRKACB,TRIM13,RBCK1,PPARG,ANK2,HSPA5,ARRDC3,GMFB,CAV1,SGK2,SERGEF,ZNF622,DNAJC1,TP53BP1,CTAGE5,ADAM9,SGSM2,CLU,MTCH1,FN1,LAMTOR3,MAPK8IP3,TRIM15,ZIC2,SIPA1L3,BUD31,VAPB,CRADD,OBSCN,PSMA1,MEX3B,AGAP1,UBE2E1,TCF7L2,HERPUD1,TBC1D2,SPAG9,IRAK2,PPP1R12B,ARHGAP12,PRKAR2A,TESC,CEMIP,NTSR1,RIPK1,SMARCA4,PIBF1,DENND3,GBF1,KDM1A,PLXNB1,NVL,GRIN2C,DNAJB6,IKBKB,HTRA2,CASP10,ARHGAP17,GRHL3,TOR1AIP2,AKAP13,DKC1,SMAD3,ADNP,KLF4,DUSP19,ARC,SCARB1,EIF2B3,PKIB,TNIK,MINK1,SH2D3A,MAP3K13,CAMK1,DBF4,IQGAP2,PRKCH,DNMBP,FGF2,ASAP3,RAP1GDS1,RANGAP1,ARHGEF12,ARHGAP32,MEN1,PIK3CB,HSPA1B,GADD45A,SERINC1,BCAS3,MSH3,TAF12,NFKBIB,MMP16,ZAK,ARHGAP27,HRH1 |
| 1.696e-02 | -4.08 | GSE3982_NEUTROPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_NKCELL_UP | 190 | 35 | 17758 | 2279 |
CDC42EP2,B4GALT5,ACTR3,C14orf159,RNF24,ZFP36L1,WDR26,SLC25A44,DENND3,GIT2,NDUFB3,CHD7,RNF141,AMPD3,PNPLA3,CNTNAP3B,GNG5,SRPK2,DBN1,RBCK1,BRD4,FOXN3,KDM5A,EPS15L1,DHX34,C5AR1,VDR,FBXL5,MSRA,ARL4A,CFD,TBX3,VPS37B,PSAP,MAP2K4 |
| 1.696e-02 | -4.08 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_DN | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_DN | 190 | 35 | 17758 | 2279 |
SLC12A7,VIPR1,ITFG1,ARFIP2,COBLL1,RIPK1,LPCAT3,APRT,GYG1,FARSA,ANXA7,COPS3,BANF1,CORO1A,MGLL,YARS,GNG5,CDK6,TBC1D8,ATOX1,R3HDM1,MBNL2,PIK3CB,EIF3H,ZDHHC11,SERF2,HK2,TSSC1,DPEP1,PEX13,TBL1X,RBPJ,FIP1L1,BRCC3,CCNB1IP1 |
| 1.696e-02 | -4.08 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | 190 | 35 | 17758 | 2279 |
SRM,ZNF706,GNB3,TRIP6,UROD,GAS6,SSR4,REEP5,SRPRB,SLC39A7,MPST,SEC24A,SLC3A2,WBSCR22,C11orf80,TPM4,CUX1,OBSCN,YIPF3,CAV1,SMPDL3B,NEU1,PYCR1,YIF1A,TMCO1,SERF2,YIPF2,DNAJC1,VPS37B,CFD,SURF1,PAM,SIL1,COPS6,MACROD1 |
| 1.696e-02 | -4.08 | GSE7852_THYMUS_VS_FAT_TREG_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TREG_DN | 190 | 35 | 17758 | 2279 |
MIF4GD,FEM1C,PRKAB2,BHLHE40,KCNJ14,LCLAT1,FLNB,SLC38A2,NDRG4,TSHZ1,VOPP1,ZCCHC14,ATF4,GLTSCR2,RAP1GAP2,DENND4A,MAT2A,HERPUD1,NR2F1,MFN2,ZC3H12A,PLIN2,SMAD3,FAM135A,INSIG1,PER1,VPS37B,ARL13B,CASS4,PTPN4,RBPJ,NFKBIB,CEP170,PARD3,TRIM36 |
| 1.696e-02 | -4.08 | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDM_UP | 190 | 35 | 17758 | 2279 |
MVK,PRDX6,PTPRA,UBXN1,LAMTOR3,C14orf159,SLC38A5,DTNBP1,B3GNTL1,TMEM14C,C6orf89,MCEE,KRT7,CMIP,SMARCAD1,ELOVL6,IL6R,TPRA1,EVI5,TMEM186,TPK1,MRPL36,DDX3X,HELZ,PDLIM1,SH3RF1,NSMCE2,SNAP23,TAF4,PAM,FIS1,TBL1X,MACROD1,POLR1C,TMEM141 |
| 1.699e-02 | -4.08 | V$AR_Q6 | MSigDB lists | V$AR_Q6 | 236 | 42 | 17758 | 2279 |
ARHGAP26,PRPF38B,MAP2K5,DLL4,ID1,JUP,LUZP1,ACTR3,H2AFJ,OLA1,VPS45,SLC25A12,IP6K2,CORO6,UBR5,MBNL1,ANKRD54,DST,MLX,NBEA,AKNAD1,NOC3L,SIK3,WDFY3,NR6A1,NPM3,ZNF654,MARS,SGK2,NR2F1,GZF1,RPL28,TOM1L2,SYNCRIP,LUC7L3,HOXA3,CSMD3,TBL1X,TSPAN5,MID1,TNRC6A,MEF2C |
| 1.704e-02 | -4.07 | transcription from RNA polymerase I promoter | biological process | GO:0006360 | 37 | 10 | 16441 | 2138 |
UBTF,RRN3,GTF2H3,PTRF,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 1.704e-02 | -4.07 | positive regulation of response to extracellular stimulus | biological process | GO:0032106 | 37 | 10 | 16441 | 2138 |
SNW1,TRIM13,WDFY3,HIF1A,WAC,ATG7,SUPT5H,LRSAM1,PIP4K2A,AMBRA1 |
| 1.704e-02 | -4.07 | positive regulation of response to nutrient levels | biological process | GO:0032109 | 37 | 10 | 16441 | 2138 |
SNW1,TRIM13,WDFY3,HIF1A,WAC,ATG7,SUPT5H,LRSAM1,PIP4K2A,AMBRA1 |
| 1.704e-02 | -4.07 | double-stranded DNA binding | molecular function | GO:0003690 | 740 | 117 | 16491 | 2164 |
TCF12,ZNF516,SMARCA4,PBX1,HLTF,FOSL2,SMARCB1,CHD7,RRN3,NRF1,SREBF2,IKZF5,ZFHX3,DHX33,XRCC2,RELB,ZNF148,CHD2,ZNF85,MSH4,ZNF460,ETV1,KMT2A,DDN,PMS1,AEBP2,ATF4,ZNF195,PPARG,ZNF680,BAZ2A,NR6A1,ZNF480,NFIA,RFX2,CUX1,POU2F1,MEF2D,MCM2,SOX4,ZSCAN2,DDX60,GZF1,BATF3,SMAD3,UBTF,SKIL,MSX2,SMARCC1,GATA6,LSM14A,SIX5,CC2D1B,PER1,KLF4,E2F4,ARNTL,CEBPZ,RAD51B,RUNX1,DLX2,ZC3H8,ZBTB11,MEF2C,HMGA2,MCM10,EGR1,XPC,RFX1,PAX2,TCF3,DPF2,CENPB,NFX1,HES6,BARX2,MLH1,ZNF691,MLX,ZNF586,ZNF561,SUV39H2,MCM5,MBD2,MYC,YBX3,PRMT5,NRIP1,DMRT1,TERF2,MYB,TOP1,GATAD2B,ZNF675,MSX1,RREB1,PAXBP1,PSPC1,ARID5B,PRDM1,APTX,MEN1,ONECUT2,KLF6,FOXC1,TCF7L2,ZNF708,NSD1,ARID3B,ORC5,TBX3,MSH3,PURB,ZNF430,RBPJ,SMYD3,DDIT3 |
| 1.709e-02 | -4.07 | Bromodomain | interpro domains | IPR001487 | 43 | 11 | 18293 | 2341 |
BAZ1A,ASH1L,BRD4,BAZ2B,TAF1,BAZ2A,SMARCA4,BRD9,KMT2A,BRWD3,TRIM66 |
| 1.710e-02 | -4.07 | MUS81 (MUS81 structure-specific endonuclease subunit) | protein interactions | 80198 | 65 | 16 | 16036 | 2270 |
BRAF,VWCE,FANCD2,PCNXL2,PLEK2,FBXL5,ATXN7L1,SNW1,SLX4,ZNF358,DUS3L,ZNF142,TIMELESS,EME1,BRD9,TERF2 |
| 1.710e-02 | -4.07 | PLIN3 (perilipin 3) | protein interactions | 10226 | 65 | 16 | 16036 | 2270 |
VMA21,ANKMY2,LGALS1,ADSL,PHGDH,CLNS1A,ATIC,DSG2,TBPL1,IGBP1,LRSAM1,PDLIM5,SRP14,PPA1,IPO11,HN1 |
| 1.710e-02 | -4.07 | MPG (N-methylpurine DNA glycosylase) | protein interactions | 4350 | 65 | 16 | 16036 | 2270 |
SART1,RFC4,PRPF38B,PPARG,TFIP11,GNL3,ELP3,OBSCN,EIF2A,IKBKAP,RPA1,TERF2IP,KDM2A,ELP2,DHX33,HSD17B14 |
| 1.711e-02 | -4.07 | regulation of chromatin modification | biological process | GO:1903308 | 137 | 27 | 16441 | 2138 |
WDR61,PAXBP1,SUPT6H,KDM5A,CAMK1,BCOR,BRCA1,SETD7,RPS6KA5,UBR5,KDM1A,SKI,SNCA,SMARCB1,PAF1,RNF40,TADA3,SNW1,NSD1,CAMK2D,CDK9,SET,ATG7,CTR9,NCOR1,KMT2A,MYB |
| 1.713e-02 | -4.07 | CobW/HypB/UreG_dom | interpro domains | IPR003495 | 5 | 3 | 18293 | 2341 |
CBWD1,CBWD6,CBWD5 |
| 1.713e-02 | -4.07 | FYrich_C | interpro domains | IPR003889 | 5 | 3 | 18293 | 2341 |
KMT2D,KMT2C,KMT2A |
| 1.713e-02 | -4.07 | BCDHK/PDK_N | interpro domains | IPR018955 | 5 | 3 | 18293 | 2341 |
BCKDK,PDK1,PDK4 |
| 1.713e-02 | -4.07 | WHIM3_domain | interpro domains | IPR028935 | 5 | 3 | 18293 | 2341 |
BAZ1A,BAZ2B,BAZ2A |
| 1.713e-02 | -4.07 | Znf_C5HC2 | interpro domains | IPR004198 | 5 | 3 | 18293 | 2341 |
KDM5C,KDM5B,KDM5A |
| 1.713e-02 | -4.07 | DDT_dom_superfamily | interpro domains | IPR018501 | 5 | 3 | 18293 | 2341 |
BAZ1A,BAZ2B,BAZ2A |
| 1.713e-02 | -4.07 | PABP_1234 | interpro domains | IPR006515 | 5 | 3 | 18293 | 2341 |
PABPC1L,PABPC1,PABPC4 |
| 1.713e-02 | -4.07 | His_kinase_dom | interpro domains | IPR005467 | 5 | 3 | 18293 | 2341 |
BCKDK,PDK1,PDK4 |
| 1.713e-02 | -4.07 | Znf_Rad18_put | interpro domains | IPR006642 | 5 | 3 | 18293 | 2341 |
RAD18,POLK,FAN1 |
| 1.713e-02 | -4.07 | Laminin_aI | interpro domains | IPR009254 | 5 | 3 | 18293 | 2341 |
LAMA4,LAMA2,LAMA5 |
| 1.713e-02 | -4.07 | FYrich_N | interpro domains | IPR003888 | 5 | 3 | 18293 | 2341 |
KMT2D,KMT2C,KMT2A |
| 1.713e-02 | -4.07 | DUF4704 | interpro domains | IPR031570 | 5 | 3 | 18293 | 2341 |
NBEA,NBEAL1,WDFY3 |
| 1.713e-02 | -4.07 | DDT_dom_subgr | interpro domains | IPR018500 | 5 | 3 | 18293 | 2341 |
BAZ1A,BAZ2B,BAZ2A |
| 1.713e-02 | -4.07 | WHIM1_dom | interpro domains | IPR028942 | 5 | 3 | 18293 | 2341 |
BAZ1A,RSF1,BAZ2A |
| 1.713e-02 | -4.07 | AWS_dom | interpro domains | IPR006560 | 5 | 3 | 18293 | 2341 |
NSD1,ASH1L,SETD2 |
| 1.713e-02 | -4.07 | Laminin_domII | interpro domains | IPR010307 | 5 | 3 | 18293 | 2341 |
LAMA4,LAMA2,LAMA5 |
| 1.713e-02 | -4.07 | Cbl_biosynth_CobW-like_C | interpro domains | IPR011629 | 5 | 3 | 18293 | 2341 |
CBWD1,CBWD6,CBWD5 |
| 1.713e-02 | -4.07 | BRK_domain | interpro domains | IPR006576 | 5 | 3 | 18293 | 2341 |
SMARCA4,CHD7,CHD9 |
| 1.717e-02 | -4.06 | transcription from RNA polymerase II promoter | biological process | GO:0006366 | 768 | 120 | 16441 | 2138 |
ZNF292,TCF12,ZNF516,ASH1L,PRKAB2,PBX1,HLTF,SNAPC4,SKI,NRF1,SRSF2,ZFHX3,CAMTA2,RNF111,ZNF148,MEIS3,CPSF3,ETV1,KMT2A,LSM10,TRIP13,MAML3,DEAF1,SESN2,ATF4,RNMT,PPARG,NR6A1,MED27,GRHL3,NFIA,TCEB3,CUX1,C5AR1,MED16,SOX4,TAF9B,BATF3,VDR,TAF2,PAF1,SMAD3,SKIL,GLS,MSX2,SUPT4H1,ELP2,GATA6,CCNT1,KLF4,COPS5,E2F4,G6PD,CEBPZ,RUNX1,NFRKB,DLX2,MED20,ZC3H8,NOCT,MEF2C,HMGA2,NCOR2,EGR1,TAF1,PAX2,LAMTOR3,SMAD7,NFX1,BARX2,MED18,IKBKAP,CDC73,CHD5,FOXO3,DDIT4,ELL,SNW1,SUB1,SCAF1,TAF3,MYC,GTF2H1,MED24,ICE2,DMRT1,PKNOX1,SNAPC5,MYB,GTF2H3,MSX1,RREB1,STAG1,TEAD1,KDM5A,ELP3,SETD2,NELFA,MEN1,SUPT5H,ONECUT2,FOXC1,UBC,NR2F1,POLR2A,GTF2A1,HIF1A,ARID3B,CDK9,MED15,TAF4,CSRNP1,RRAGA,TBPL1,NCBP2,RBPJ,TAF12,NCOR1,DDIT3,NR2C2AP |
| 1.719e-02 | -4.06 | adenofibroma | COSMIC cancer mutations | adenofibroma | 5 | 3 | 17775 | 2278 |
BRCA2,BRAF,BRCA1 |
| 1.719e-02 | -4.06 | ovary-adenoma-adenofibroma | COSMIC cancer mutations | ovary-adenoma-adenofibroma | 5 | 3 | 17775 | 2278 |
BRCA2,BRAF,BRCA1 |
| 1.721e-02 | -4.06 | phenethylamine:oxygen oxidoreductase (deaminating) activity | molecular function | GO:0052596 | 2 | 2 | 16491 | 2164 |
AOC3,AOC2 |
| 1.721e-02 | -4.06 | aliphatic-amine oxidase activity | molecular function | GO:0052595 | 2 | 2 | 16491 | 2164 |
AOC3,AOC2 |
| 1.721e-02 | -4.06 | dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity | molecular function | GO:0042281 | 2 | 2 | 16491 | 2164 |
ALG6,ALG8 |
| 1.721e-02 | -4.06 | tryptamine:oxygen oxidoreductase (deaminating) activity | molecular function | GO:0052593 | 2 | 2 | 16491 | 2164 |
AOC3,AOC2 |
| 1.721e-02 | -4.06 | succinate-CoA ligase (GDP-forming) activity | molecular function | GO:0004776 | 2 | 2 | 16491 | 2164 |
SUCLG2,SUCLG1 |
| 1.721e-02 | -4.06 | tyrosine binding | molecular function | GO:0072545 | 2 | 2 | 16491 | 2164 |
YARS2,GPR143 |
| 1.721e-02 | -4.06 | histidine-tRNA ligase activity | molecular function | GO:0004821 | 2 | 2 | 16491 | 2164 |
HARS2,HARS |
| 1.721e-02 | -4.06 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity | molecular function | GO:0004119 | 2 | 2 | 16491 | 2164 |
PDE3B,PDE3A |
| 1.721e-02 | -4.06 | asparagine-tRNA ligase activity | molecular function | GO:0004816 | 2 | 2 | 16491 | 2164 |
NARS2,NARS |
| 1.721e-02 | -4.06 | histone deacetylase activity (H4-K16 specific) | molecular function | GO:0034739 | 2 | 2 | 16491 | 2164 |
SIRT2,SIRT7 |
| 1.721e-02 | -4.06 | RNA polymerase I transcription factor binding | molecular function | GO:0001179 | 2 | 2 | 16491 | 2164 |
CAV1,POLR1E |
| 1.721e-02 | -4.06 | tryptophan-tRNA ligase activity | molecular function | GO:0004830 | 2 | 2 | 16491 | 2164 |
WARS2,WARS |
| 1.721e-02 | -4.06 | glycerophosphocholine phosphodiesterase activity | molecular function | GO:0047389 | 2 | 2 | 16491 | 2164 |
GDPD5,GPCPD1 |
| 1.721e-02 | -4.06 | aminoacetone:oxygen oxidoreductase(deaminating) activity | molecular function | GO:0052594 | 2 | 2 | 16491 | 2164 |
AOC3,AOC2 |
| 1.721e-02 | -4.06 | tyrosine-tRNA ligase activity | molecular function | GO:0004831 | 2 | 2 | 16491 | 2164 |
YARS,YARS2 |
| 1.721e-02 | -4.06 | acetyltransferase activator activity | molecular function | GO:0010698 | 2 | 2 | 16491 | 2164 |
PDCD5,BCAS3 |
| 1.721e-02 | -4.06 | peptide-methionine (S)-S-oxide reductase activity | molecular function | GO:0008113 | 2 | 2 | 16491 | 2164 |
MSRA,TXN2 |
| 1.721e-02 | -4.06 | U4atac snRNA binding | molecular function | GO:0030622 | 2 | 2 | 16491 | 2164 |
SNU13,PRPF31 |
| 1.726e-02 | -4.06 | KANG_GIST_WITH_PDGFRA_DN | MSigDB lists | KANG_GIST_WITH_PDGFRA_DN | 5 | 3 | 17758 | 2279 |
SVIL,TSPAN5,NAMPT |
| 1.726e-02 | -4.06 | JONES_TCOF1_TARGETS | MSigDB lists | JONES_TCOF1_TARGETS | 5 | 3 | 17758 | 2279 |
PMAIP1,ZMAT3,PERP |
| 1.726e-02 | -4.06 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_6 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_6 | 5 | 3 | 17758 | 2279 |
RABEP1,MAP2K4,PER1 |
| 1.729e-02 | -4.06 | protein binding involved in cell adhesion | molecular function | GO:0098631 | 17 | 6 | 16491 | 2164 |
NFASC,DSC2,JUP,DSP,DSG2,ITGA2 |
| 1.738e-02 | -4.05 | ANNEXIN | prosite domains | PS00223 | 13 | 5 | 11866 | 1504 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 1.741e-02 | -4.05 | GTTTGTT,MIR-495 | MSigDB lists | GTTTGTT,MIR-495 | 243 | 43 | 17758 | 2279 |
UBN1,TNFRSF21,TMEM183A,FAM122B,TGFB2,RLF,FOXO3,DDIT4,ANAPC1,RGS17,UBE3A,SLC38A2,JOSD1,CELF1,DMRT1,CDK6,SOX6,MAML3,BDNF,GPM6A,CRIM1,NR6A1,HSPA5,GMFB,RSBN1,PNN,FAM126B,R3HDM2,CYB5B,MBNL2,PHF6,DDX3X,MGAT2,ZFAND3,IREB2,HSDL2,ADAT2,LUC7L3,LARGE,VPS13D,FKBP5,C18orf25,TNRC6A |
| 1.742e-02 | -4.05 | Znf_C2H2 | interpro domains | IPR007087 | 766 | 118 | 18293 | 2341 |
ZNF254,ZNF292,ZNF76,ZNF516,TRERF1,ARID2,GTF2H2C,ZBTB37,ZNF107,ZNF83,ZNF709,ZNF44,ZNF121,EEA1,ZSCAN5A,ZNF37A,ZNF804A,ZNF827,ZBTB21,ZNF608,ZFHX3,IKZF5,ZKSCAN1,JAZF1,HKR1,ZNF142,ZEB1,WIZ,ZFP37,ZNF148,ZNF85,ZNF460,ZNF3,PRMT3,ZNF646,ZBTB17,DPF3,AEBP2,ZNF124,ZNF195,ZNF680,ZNF414,ZNF480,ZSCAN2,ZNF91,ZNF251,ZNF197,ZBTB25,GZF1,ZNF622,ZNF266,RBSN,IKZF4,ADNP,ZNF557,KLF4,ZNF333,ZNF236,ZNF81,HIC2,ZNF436,ZNF18,ZNF397,ZBTB11,ZNF598,ZNF589,ZNF532,ZNF507,ZNF786,EGR1,DPF2,ZNF280C,MYNN,ZIC2,ZNF691,ZNF346,RLF,POGZ,ZNF594,ZNF483,ZNF239,ZNF358,ZNF354A,ZNF586,ZNF561,ZNF710,ZNF518B,ZNF629,TSHZ1,ZNF675,ZNF234,RREB1,ZNF821,ZNF587,PRDM16,ZNF654,ZFP14,ZNF512B,ZNF324B,PRDM1,APTX,ZNF467,ZNF407,KLF6,ZNF850,ZNF655,ZNF221,ZNF708,ZFP62,ZNF425,ZNF155,ZBTB12,ZNF160,ZNF430,ZFP90,ZNF32,ZFHX2,ZBTB24 |
| 1.742e-02 | -4.05 | CCNL1 (cyclin L1) | protein interactions | 57018 | 8 | 4 | 16036 | 2270 |
JMJD6,SRSF2,TFIP11,ISG15 |
| 1.742e-02 | -4.05 | DENND6A (DENN/MADD domain containing 6A) | protein interactions | 201627 | 8 | 4 | 16036 | 2270 |
EFNB2,TGFBR2,RPS6KC1,PRKCSH |
| 1.742e-02 | -4.05 | SEMA4G (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G) | protein interactions | 57715 | 8 | 4 | 16036 | 2270 |
DLG4,LIG4,ATXN1,TRIP13 |
| 1.742e-02 | -4.05 | SLBP (stem-loop binding protein) | protein interactions | 7884 | 8 | 4 | 16036 | 2270 |
ERI1,LSM10,CDK6,CDK4 |
| 1.742e-02 | -4.05 | Melk (maternal embryonic leucine zipper kinase) | protein interactions | 17279 | 8 | 4 | 16036 | 2270 |
SMAD3,ZNF622,UBC,SMAD7 |
| 1.742e-02 | -4.05 | USP9Y (ubiquitin specific peptidase 9, Y-linked) | protein interactions | 8287 | 8 | 4 | 16036 | 2270 |
PMS1,SHC1,UBC,MAPT |
| 1.742e-02 | -4.05 | PCSK7 (proprotein convertase subtilisin/kexin type 7) | protein interactions | 9159 | 8 | 4 | 16036 | 2270 |
PCSK7,SYNCRIP,PABPC1,HSPA5 |
| 1.742e-02 | -4.05 | PDCD2L (programmed cell death 2-like) | protein interactions | 84306 | 8 | 4 | 16036 | 2270 |
NAP1L5,COPS6,PRMT3,SRP14 |
| 1.742e-02 | -4.05 | ADH6 (alcohol dehydrogenase 6 (class V)) | protein interactions | 130 | 8 | 4 | 16036 | 2270 |
RSL1D1,ANKRD17,RPAIN,RPS29 |
| 1.742e-02 | -4.05 | GUCY1A3 (guanylate cyclase 1, soluble, alpha 3) | protein interactions | 2982 | 8 | 4 | 16036 | 2270 |
CSNK2A1,COPS4,AGAP1,COPS5 |
| 1.742e-02 | -4.05 | LIPT1 (lipoyltransferase 1) | protein interactions | 51601 | 8 | 4 | 16036 | 2270 |
METTL15,MPP6,SUFU,UBR1 |
| 1.742e-02 | -4.05 | NUDT12 (nudix hydrolase 12) | protein interactions | 83594 | 8 | 4 | 16036 | 2270 |
SIRT2,PDLIM1,BLMH,VWA8 |
| 1.742e-02 | -4.05 | CCDC124 (coiled-coil domain containing 124) | protein interactions | 115098 | 8 | 4 | 16036 | 2270 |
ADARB1,ZNF346,APEX1,RPS6KB2 |
| 1.742e-02 | -4.05 | SH3YL1 (SH3 and SYLF domain containing 1) | protein interactions | 26751 | 8 | 4 | 16036 | 2270 |
VIM,HELZ,KHDRBS1,VPS37B |
| 1.742e-02 | -4.05 | HSFX1 (heat shock transcription factor family, X-linked 1) | protein interactions | 100506164 | 8 | 4 | 16036 | 2270 |
FAM192A,ATXN1,CCDC57,VCAN |
| 1.743e-02 | -4.05 | IKEDA_MIR133_TARGETS_UP | MSigDB lists | IKEDA_MIR133_TARGETS_UP | 43 | 11 | 17758 | 2279 |
DDX3X,CYLD,HIF1A,DNAJB6,ACTR3,MYH9,RBPJ,PITPNB,FMNL2,HS2ST1,SLC23A2 |
| 1.745e-02 | -4.05 | programmed cell death | biological process | GO:0012501 | 1074 | 163 | 16441 | 2138 |
POLB,CUL4A,NF1,TNFRSF21,TMEM109,CSNK2A1,SIRT2,CHAC1,PRKCA,NLE1,BIRC2,CIAPIN1,MRPS30,NEK6,PMAIP1,ATG3,FNIP2,YARS,AVEN,TIMM50,ATF4,PPARG,C5AR1,MCL1,SHISA5,CAV1,BRCA1,SAP30BP,DDX3X,ZNF622,BRCA2,SH3RF1,ARL6IP5,TNFRSF1A,FIS1,PPP3CC,CLU,ZC3H8,TNFRSF10D,ZMAT3,MTCH1,MEF2C,IFT57,FOXO1,SLK,PAX2,TRIO,DPF2,CDIP1,ZFP36L1,PDCD7,TGFBR2,PDCD5,RHBDD1,DDIT4,PRKCE,MYC,ANP32B,PRF1,PEA15,KRT20,CRADD,STPG1,PSMA1,RYR2,LIG4,OBSCN,SRA1,HERPUD1,MYBBP1A,KPNA1,HK2,RRAGA,PTRH2,DPEP1,BRSK2,ARHGAP10,MAP2K4,SART1,MAP2K5,CYLD,BIRC6,RIPK1,SEMA6A,BLOC1S2,BRE,PPID,DNAJB6,SHF,BCAP29,RMDN3,FHIT,PEG10,KMT2A,CASP10,PERP,CASP8AP2,HTRA2,PRAME,PDK1,DDX41,PARP2,LGALS1,VIM,MEF2D,AKAP13,DSP,SNCA,SMAD3,ZC3H12A,KLF4,HIPK2,DNAJA3,SLC4A7,TRAF3,RPS6KB1,RNF130,BAG1,MAPT,MAP1S,RTN4,MLH1,GAS6,ZNF346,OPA1,TGFB2,NOL3,FOXO3,PHLDA2,PSMF1,MFSD10,ABL1,SNW1,CTNNBL1,DSG2,TRIAP1,NISCH,S100A14,CD44,SPTAN1,TOP1,ARHGEF12,PTK2,IL6R,CAAP1,UBE2K,RHOT2,UBC,MFN2,TRIB3,GADD45A,CUL2,CSRNP1,TMEM219,AEN,ATM,APAF1,PGAM5,IGBP1,RABEP1,KIF1B,DDIT3,STK4 |
| 1.747e-02 | -4.05 | APC/C:Cdc20 mediated degradation of Cyclin B | REACTOME pathways | R-HSA-174048 | 21 | 7 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBC,UBE2E1,ANAPC11,ANAPC10 |
| 1.754e-02 | -4.04 | regulation of cellular component organization | biological process | GO:0051128 | 2113 | 306 | 16441 | 2138 |
MYCBP2,SYNJ1,RAC3,LPAR3,UBR5,AMBRA1,SKI,TOM1L1,NEK6,SREBF2,S100A10,PMAIP1,MAD1L1,DPH6,FNIP2,HRG,FXN,TBC1D8,LIMA1,NOL8,CUX1,WDHD1,CAMSAP2,SEMA3F,STOML2,DDX3X,SKIL,FIS1,SEMA3C,TPM1,NRP1,SYNPO,MEF2C,WDR75,CDC42EP2,CELSR1,OPHN1,PID1,BTBD9,PDCD5,ABCA7,PRKCE,CHN1,CNST,ASAP1,MYC,PRMT5,CAV2,FMNL2,TERF2,MYB,BDNF,EXOSC2,IFRD1,SYNGAP1,WDR61,RREB1,MYO10,RAP1GAP2,RAP1B,ATAT1,SNAP25,EVI5,PLCB1,TRIM37,ARIH2,KIDINS220,RPL28,PMEPA1,HIF1A,LEMD3,CDK9,CCDC85B,CNOT6,NCOR1,PDLIM5,SGSM3,DNM3,MAP2K5,SYT17,PAFAH1B1,C16orf45,ACTR3,DDR2,MYH9,STAM,HSPA1A,UBL5,PDE3A,TERF2IP,SLX4,ACD,TBC1D22A,FMNL1,MMP14,TTC3,KMT2A,WDPCP,LGALS1,ARHGEF10,PREX1,DLG4,SETD7,TBC1D16,FGFR1,SNCA,DCBLD2,MSX2,ARHGAP21,CAMK2D,CDC16,NSMCE2,PEMT,IFT140,ANXA2,MID1,MAPT,SSH2,BRAF,RTN4,GAS6,IP6K2,OPA1,TGFB2,NOL3,RPS6KA5,MAD2L2,NEDD4,TADA3,ABL1,SNW1,CFDP1,UNC13A,TRIAP1,RDX,NLGN3,EXOSC4,ACTR3B,SPTAN1,DDHD1,PXN,CEP295,PTK2,ANXA1,INF2,KLHL22,NSD1,STX1A,STX18,ATM,APAF1,BMP4,BRWD3,UQCC1,ANAPC4,CUL7,ATRX,MFGE8,CSNK2A1,BCOR,SIRT2,BIRC2,SMARCB1,ABL2,ANAPC1,RAP1A,ARHGAP18,YLPM1,ATG3,ANAPC11,NCKIPSD,ANAPC10,HYAL1,CARM1,ZBTB17,DBN1,FMNL3,TNK2,GPM6A,GCNT2,PPARG,GMFB,HDAC8,BRCA1,CAV1,SGK2,TAF9B,ARPC3,RHOU,PAF1,EPN2,INSIG1,TOM1L2,PQBP1,ADAM9,DPP4,PPP3CC,CLU,UQCC2,C2CD5,CHMP4C,FN1,STX8,TAF1,STXBP6,PAX2,NKD2,SMAD7,SPIRE1,RNF40,ATXN2,NDRG4,SEMA3D,CTR9,TENM3,LRSAM1,PAXBP1,MEX3B,SYT1,UBE2E1,TCF7L2,TBC1D2,BICD1,FSCN1,PFDN2,NAPA,FNBP1L,CHMP2A,FEZ2,CYLD,ID1,CEMIP,GPR143,TBCCD1,SMARCA4,ST7L,SEMA6A,PLXNB1,SBDS,KDM1A,MIEF1,VPS18,RRN3,LYPLAL1,DNAJB6,IKBKB,ETF1,CORO1A,ITGAX,SPIDR,HTRA2,CTC1,WDR36,PHLDB2,EVL,RAB7A,GRHL3,VIM,DKC1,ENC1,USP36,SMAD3,ADNP,ATG7,SCARB1,ARC,AP2S1,PKIB,UNC13D,TNIK,DNAJA4,SUPT6H,CAMK1,ARFIP2,MAP1S,CLSTN2,ATF7IP,SEMA3E,PPP1R1C,CSNK1A1,PIP4K2A,IQGAP2,PRKCH,SACS,ANXA7,HAS3,SCN1B,FBXO31,AMOT,DMRT1,PPP1R9B,MSX1,CRIM1,KDM5A,ASAP3,TEX14,FERMT2,PIK3CB,NEU1,POLR3A,HSPA1B,DKK1,MPP7,SET,VPS37B,BCAS3 |
| 1.758e-02 | -4.04 | GSE20715_0H_VS_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_DN | 197 | 36 | 17758 | 2279 |
BANP,DNAJA4,ID1,LUZP1,PRDX6,BIRC6,PDE4B,PLOD1,STAM,NAMPT,KCTD11,MCM5,SERPINH1,ERRFI1,ZC3H3,PPA1,PKNOX1,TOP1,FAM120B,TSHZ1,MPP6,PSAT1,POLA1,HOMER2,HSPA5,LDHA,SLC23A2,RHOU,POLE2,SYNCRIP,H2AFX,HSPB8,XPNPEP1,FKBP5,BPNT1,DDIT3 |
| 1.758e-02 | -4.04 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN | 197 | 36 | 17758 | 2279 |
TNNC1,ASH1L,EGR1,STX8,DLGAP4,CSNK2A1,MAP2K3,CHD7,RRN3,FMNL1,RELB,MED24,POLR1B,CNOT4,HMGCR,RABEPK,ZBTB17,PXN,TXLNG,ZNF821,POLK,TLE3,PACRGL,C5AR1,LRRC8A,ZNFX1,MEN1,ARRDC4,DDX49,MGST1,HLA-DMA,SKIL,GADD45A,PER1,PQBP1,DDIT3 |
| 1.759e-02 | -4.04 | MAPK3 (mitogen-activated protein kinase 3) | protein interactions | 5595 | 209 | 41 | 16036 | 2270 |
PHF3,BRAF,TTC27,VTA1,TCF3,LAMTOR3,ID2,RCAN1,UBR5,MAP2K3,PRKCE,ASNS,SREBF2,MYC,NCKIPSD,VPS52,MAP3K14,AMOT,ETV1,HTRA2,PEA15,PXN,KIRREL2,GMFB,KSR2,FERMT2,CAV1,BRCA1,PLCB1,SNCA,VDR,UBTF,TP53BP1,L3MBTL3,HIF1A,HSPB8,RPS6KB1,METTL2B,NMD3,RNF114,GALE |
| 1.759e-02 | -4.04 | integrator complex | cellular component | GO:0032039 | 13 | 5 | 17570 | 2233 |
INTS12,INTS7,INTS5,CPSF3L,INTS9 |
| 1.759e-02 | -4.04 | DNA-directed RNA polymerase I complex | cellular component | GO:0005736 | 13 | 5 | 17570 | 2233 |
POLR1B,POLR1C,ZNRD1,POLR1E,POLR1A |
| 1.759e-02 | -4.04 | Prp19 complex | cellular component | GO:0000974 | 13 | 5 | 17570 | 2233 |
BCAS2,CTNNBL1,POLR2A,PLRG1,PRPF19 |
| 1.760e-02 | -4.04 | RNA Polymerase II Promoter Escape | REACTOME pathways | R-HSA-73776 | 46 | 12 | 8202 | 1117 |
TAF2,GTF2H3,GTF2A1,GTF2H2C,TAF1,TAF3,AK6,TAF4,GTF2H1,TAF12,POLR2A,TAF9B |
| 1.760e-02 | -4.04 | RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | REACTOME pathways | R-HSA-73779 | 46 | 12 | 8202 | 1117 |
TAF2,GTF2H3,GTF2A1,GTF2H2C,TAF1,TAF3,AK6,TAF4,GTF2H1,TAF12,POLR2A,TAF9B |
| 1.760e-02 | -4.04 | RNA Polymerase II Transcription Initiation And Promoter Clearance | REACTOME pathways | R-HSA-76042 | 46 | 12 | 8202 | 1117 |
TAF2,GTF2H3,GTF2A1,GTF2H2C,TAF1,TAF3,AK6,TAF4,GTF2H1,TAF12,POLR2A,TAF9B |
| 1.760e-02 | -4.04 | DNA Damage Bypass | REACTOME pathways | R-HSA-73893 | 46 | 12 | 8202 | 1117 |
RFC4,RFC3,CUL4A,RAD18,POLE2,POLK,RCHY1,USP10,MAD2L2,UBC,ISG15,RPA1 |
| 1.760e-02 | -4.04 | HIV Transcription Initiation | REACTOME pathways | R-HSA-167161 | 46 | 12 | 8202 | 1117 |
TAF2,GTF2H3,GTF2A1,TAF1,TAF3,GTF2H2C,AK6,TAF4,GTF2H1,TAF12,POLR2A,TAF9B |
| 1.760e-02 | -4.04 | RNA Polymerase II HIV Promoter Escape | REACTOME pathways | R-HSA-167162 | 46 | 12 | 8202 | 1117 |
TAF2,GTF2H3,GTF2A1,TAF1,TAF3,GTF2H2C,AK6,TAF4,GTF2H1,TAF12,POLR2A,TAF9B |
| 1.760e-02 | -4.04 | RNA Polymerase II Transcription Initiation | REACTOME pathways | R-HSA-75953 | 46 | 12 | 8202 | 1117 |
TAF2,GTF2H3,GTF2A1,GTF2H2C,TAF1,TAF3,AK6,TAF4,GTF2H1,TAF12,POLR2A,TAF9B |
| 1.760e-02 | -4.04 | squamous_cell_carcinoma | COSMIC cancer mutations | squamous_cell_carcinoma | 17441 | 2248 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,WDHD1,C5AR1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,SLC25A26,ZNF532,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,YTHDF2,TIMM44,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,RTN4RL2,NPW,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,ATP6V1A,NPAS2,AGAP6,HSPA1A,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,GMFB,COL4A3BP,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,ITPRIPL1,FAM135A,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,TSPAN2,ZNF586,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,D2HGDH,ZBTB12,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,MDN1,KLHDC4,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,GALNT10,DMTF1,VIPR1,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,NSUN6,H2AFJ,LETMD1,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,RERE,MFN2,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,PSMG1,MARCKSL1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,PLXNB1,FDX1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,CAT,SEC31A,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,DNTTIP1,MSX2,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,LRP3,ATP6V0D1,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,METTL2A,GRHL3,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,IGF2BP2,WDR26,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,ANKRD30BL,VPS37B,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RASSF3,FAAH2,RABGAP1L,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,LGALS1,ATP6V0A1,FGFR1,TAF2,GNG2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,MCM6,PGPEP1,STX8,ITPRIP,LRRC28,MEX3A,HSD17B10,HES6,BARX2,ZFP36L1,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,PALB2,SYNCRIP,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,GPC2,SRBD1,ZBTB8OS,SET,MSH3,EIF2S1,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,CEP135,MEIS3,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,TTYH2,PTPN12,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27 |
| 1.761e-02 | -4.04 | EIF4A1 (eukaryotic translation initiation factor 4A1) | protein interactions | 1973 | 76 | 18 | 16036 | 2270 |
CUL7,FN1,ATP6V1A,SIRT7,HSPA5,EIF4A2,LAGE3,LIG4,ABCC2,TRAP1,UCHL5,MYC,COPS5,H2AFX,UPF2,FUS,SRRM2,PABPC1 |
| 1.761e-02 | -4.04 | TAF9 (TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa) | protein interactions | 6880 | 76 | 18 | 16036 | 2270 |
TAF1,ANK2,KLF6,TAF9B,TAF2,TADA3,ATXN7,KPNA1,TRRAP,ELP2,MYC,TAF4,RNF138,CHD2,NCOR1,TAF12,FBL,KMT2A |
| 1.761e-02 | -4.04 | GFI1B (growth factor independent 1B transcription repressor) | protein interactions | 8328 | 76 | 18 | 16036 | 2270 |
RAB11FIP4,TRIP6,TAF1,MON1A,VSNL1,CENPB,RCHY1,BRCA1,KDM1A,PHC2,BRE,EHMT2,DNAJA3,ATXN2,COPS5,CCDC85B,PDLIM5,ZNRD1 |
| 1.761e-02 | -4.04 | GCN1 (GCN1 eIF2 alpha kinase activator homolog) | protein interactions | 10985 | 76 | 18 | 16036 | 2270 |
NDUFA5,CAMKK2,CUL7,FN1,HARS,PRKAB2,SIRT7,HNRNPA3,HSPA1A,INF2,SNW1,EIF2S2,NEK6,GTF2A1,MYC,ANXA5,RNF2,BMI1 |
| 1.762e-02 | -4.04 | V$ATF_B | MSigDB lists | V$ATF_B | 184 | 34 | 17758 | 2279 |
SPRED2,CYLD,ID1,MAP3K13,PAFAH1B1,DDX19A,OSBPL9,PPP2R2A,RCAN1,MBNL1,RING1,BRE,MCAM,SUV39H2,THADA,VGF,IKBKB,ANAPC10,CTC1,AGPAT4,LDHA,SULT4A1,PACRGL,TEX14,GNL1,SNAP25,MBNL2,DNTTIP1,CAMK2D,SPAG9,TRAP1,PER1,VPS37B,ZBTB11 |
| 1.762e-02 | -4.04 | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP | 184 | 34 | 17758 | 2279 |
TNIK,WDR74,DLGAP4,APRT,PRKCA,LPIN1,PHC2,ABL1,CTNNBL1,ERI1,RABGAP1L,TRMU,NCKIPSD,ZNF3,DENND1A,LONP1,IPO11,SPAG6,C18orf21,EIF4E3,PCCA,LGALS1,TBXAS1,TOR1AIP2,DLST,LSG1,TARS,FGFR1,HTR7,HELZ,FSCN1,DPEP1,IQSEC2,ZAK |
| 1.762e-02 | -4.04 | E2F1_UP.V1_UP | MSigDB lists | E2F1_UP.V1_UP | 184 | 34 | 17758 | 2279 |
EFNB2,DNAJC2,MCM10,UBN1,DBF4,NUP43,PIP4K2A,PITPNM1,NOP56,DCTPP1,CAD,ZSWIM7,LPIN2,LARP4B,PRADC1,FMNL3,EVL,PRIM2,ARHGAP39,USP10,WDHD1,PACS1,GUF1,ATP5D,SLC7A1,KPNA1,BRCA2,GATA6,KPNA3,VPS37B,MSH3,TRAF3,MED20,NOLC1 |
| 1.762e-02 | -4.04 | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | 184 | 34 | 17758 | 2279 |
CHST11,CLK1,RFX1,ZFP36L1,DENND3,NPRL2,SNW1,MLX,S100A10,ASAP1,CEP290,USPL1,MBD2,WAC,PMPCA,ZNF85,CMPK1,VCL,NT5E,LAMC1,ARID5B,RAP1GAP2,TCEB3,STK10,ANXA1,SLC23A2,CAT,BAZ2B,VCAN,CFD,TAF4,RBM26,ANKS1A,KDM4C |
| 1.762e-02 | -4.04 | positive regulation of muscle organ development | biological process | GO:0048636 | 48 | 12 | 16441 | 2138 |
EFNB2,FGF9,GATA6,FGF2,MKL2,ARNTL,RPS6KB1,RBPJ,BMP4,FGFR1,HMGCR,MEF2C |
| 1.762e-02 | -4.04 | negative regulation of response to DNA damage stimulus | biological process | GO:2001021 | 48 | 12 | 16441 | 2138 |
HMGA2,THOC5,BRD4,TMEM161A,TRIAP1,CLU,CD44,UBR5,OGG1,KDM1A,TERF2,TAF9B |
| 1.762e-02 | -4.04 | positive regulation of striated muscle tissue development | biological process | GO:0045844 | 48 | 12 | 16441 | 2138 |
EFNB2,FGF9,GATA6,FGF2,MKL2,ARNTL,RPS6KB1,RBPJ,BMP4,FGFR1,HMGCR,MEF2C |
| 1.765e-02 | -4.04 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | 114 | 23 | 17758 | 2279 |
POLB,FGF2,SMAD7,MARS,CAV1,BRCA1,TGFB2,PRKCA,MTR,FGFR1,ABL1,IDI1,SHC1,GADD45A,TANK,UMPS,GSTA4,APAF1,PRKACB,PERP,FDFT1,SPTAN1,HMGCR |
| 1.765e-02 | -4.04 | VTN (vitronectin) | protein interactions | 7448 | 87 | 20 | 16036 | 2270 |
SNU13,CUL7,CRADD,FGF2,WDR18,NFIA,CSNK2A1,PRKCA,TGFB2,PHGDH,DSP,SMARCB1,ADH5,HNRNPR,COPS5,LUC7L3,BUD31,HNRNPM,SF3A1,PRPF19 |
| 1.768e-02 | -4.04 | human chr2q32 | chromosome location | human chr2q32 | 11 | 4 | 26250 | 2590 |
SLC40A1,DLX2,INPP1,TFPI |
| 1.771e-02 | -4.03 | V$SP1_01 | MSigDB lists | V$SP1_01 | 230 | 41 | 17758 | 2279 |
TCF12,DNM3,DLL4,OSBPL9,SLC2A1,RNF24,JMJD6,SSR4,GBF1,BZW2,RING1,TADA3,KDM2A,PI4KB,FBXL19,BDNF,NRAS,SESN2,ZNF414,ANKMY2,PPP1R21,KCNMA1,IDH3G,RDH10,TPM4,ATAT1,POU2F1,ATXN1,PACS1,MEX3B,ARID1A,RAB10,PUSL1,C1orf122,EPN2,SYNCRIP,ZBTB8OS,HOXA3,NR2F2,HS2ST1,GALE |
| 1.779e-02 | -4.03 | SONG_TARGETS_OF_IE86_CMV_PROTEIN | MSigDB lists | SONG_TARGETS_OF_IE86_CMV_PROTEIN | 60 | 14 | 17758 | 2279 |
FLAD1,RFC4,RFC3,MCM6,POLA1,MCM5,PSMC3IP,H2AFX,UMPS,SLC29A1,MCM2,NUP214,RPA1,TMPO |
| 1.779e-02 | -4.03 | BILD_SRC_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_SRC_ONCOGENIC_SIGNATURE | 60 | 14 | 17758 | 2279 |
LSS,ASH1L,SACS,SSFA2,KDM4B,TSPYL4,EHMT1,MARCH6,CSNK1A1,ZBTB11,DMTF1,DCBLD2,VPS13B,TMCC1 |
| 1.779e-02 | -4.03 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 60 | 14 | 17758 | 2279 |
GPM6A,MAP2K5,CLSTN2,FARS2,PBX1,SEMA3C,PEG10,PTPRG,PERP,NR2F1,TPK1,PCDH7,NT5E,MAN1A1 |
| 1.779e-02 | -4.03 | BILBAN_B_CLL_LPL_UP | MSigDB lists | BILBAN_B_CLL_LPL_UP | 60 | 14 | 17758 | 2279 |
SLC39A14,SERINC5,DNMBP,TRRAP,NSF,ST6GAL1,ATOX1,AKAP12,HEATR1,PEG10,CPT1A,FLNB,SLC23A2,TOP1 |
| 1.779e-02 | -4.03 | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | 60 | 14 | 17758 | 2279 |
SUB1,SLC3A2,GARS,ASNS,TUBA1A,LRRC28,DCTN4,ZRANB2,SHMT2,SEC16A,UBR4,HERPUD1,WARS,NDUFB3 |
| 1.779e-02 | -4.03 | MORF_RPA1 | MSigDB lists | MORF_RPA1 | 60 | 14 | 17758 | 2279 |
PWP1,RFC4,SYNCRIP,COPS5,KHDRBS1,CFDP1,SET,GTF2H1,NCBP2,POP5,POLE3,CYB5B,CLNS1A,RPA1 |
| 1.781e-02 | -4.03 | V$ATF4_Q2 | MSigDB lists | V$ATF4_Q2 | 250 | 44 | 17758 | 2279 |
CYP24A1,BRAF,ID1,NF1,MAP3K13,PAFAH1B1,TNXB,KLHL18,CHAC1,SMARCB1,JAG1,ECM1,SREBF2,THADA,IKBKB,SLC38A2,RELB,JOSD1,CHD2,ADCK4,PABPC1,CTC1,HN1,FLNC,BAZ2A,RAB7A,SMARCAD1,TEX14,TPM4,SULT4A1,MRRF,GNL1,MARCH6,MBNL2,BSN,DDX3X,MSX2,RBBP8,GTF2A1,ZZEF1,VPS37B,POLR3E,ANKS1A,LPP |
| 1.782e-02 | -4.03 | amino acid transport | biological process | GO:0006865 | 125 | 25 | 16441 | 2138 |
SLC6A16,BDNF,SLC38A6,SERINC5,SLC3A2,NF1,SLC38A1,NTSR1,PRAF2,SLC25A12,SNAP25,SLC6A8,SYT1,SLC1A1,GLS,SLC7A1,SERINC1,SLC38A5,SLC7A11,STX1A,ARL6IP5,SLC38A2,SLC25A26,SLC16A10,SLC43A1 |
| 1.783e-02 | -4.03 | positive regulation of macroautophagy | biological process | GO:0016239 | 32 | 9 | 16441 | 2138 |
TRIM13,WDFY3,HIF1A,WAC,ATG7,SUPT5H,LRSAM1,PIP4K2A,AMBRA1 |
| 1.783e-02 | -4.03 | RNA phosphodiester bond hydrolysis, exonucleolytic | biological process | GO:0090503 | 32 | 9 | 16441 | 2138 |
TOE1,EXOSC2,ERI1,CNOT6,EXOSC4,ERI3,PARN,NOCT,DIS3L2 |
| 1.783e-02 | -4.03 | regulation of transcription regulatory region DNA binding | biological process | GO:2000677 | 32 | 9 | 16441 | 2138 |
HMGA2,ZNF675,MSX2,NSD1,ID1,MSX1,MAD2L2,DDIT3,DOT1L |
| 1.785e-02 | -4.03 | double-strand break repair via nonhomologous end joining | biological process | GO:0006303 | 65 | 15 | 16441 | 2138 |
HERC2,BRE,KDM2A,TP53BP1,POLA1,NSMCE2,H2AFX,ATM,LIG4,BRCA1,HIST1H4J,MLH1,BRCC3,XRCC4,PRPF19 |
| 1.785e-02 | -4.03 | positive regulation of stem cell proliferation | biological process | GO:2000648 | 65 | 15 | 16441 | 2138 |
IRS1,HMGA2,FGF9,FBXW4,SIRT6,HIF1A,MYC,FZD3,TBX3,SMARCD3,BMP4,TGFBR2,KDM1A,N4BP2L2,FGFR1 |
| 1.787e-02 | -4.02 | TGANTCA_V$AP1_C | MSigDB lists | TGANTCA_V$AP1_C | 1074 | 161 | 17758 | 2279 |
PTP4A1,PHF3,ADAMTS6,GIT2,RTN1,SRSF2,ECM1,MMP7,NEK6,S100A10,JAZF1,GPR87,ANAPC10,KDM5C,CEP135,SLC25A23,SRPK2,FAM184A,DSC3,FLNC,SLC38A6,DTNB,GPM6A,NRAS,ATF4,TXLNG,BAZ2A,SLC38A1,SHISA5,KCNH2,STOML2,GNAI1,PAF1,SUPT4H1,SH3RF1,MPV17,CSMD3,DIRAS1,RUNX1,BLMH,SYNPO,TNRC6A,MEF2C,LPP,RELL2,PRPF38B,CLDN15,ZHX3,SEC24D,ZFP36L1,TGFBR2,ETFB,ELL,UBE3A,LRSAM1,PRF1,MYB,PEA15,BDNF,LAMC1,RB1CC1,TBXAS1,PSMA1,ZNFX1,MAP7D1,PRDM1,SNAP25,ONECUT2,ANGPTL4,NCDN,DYNC1H1,TSR1,LRP1B,SPAG9,TBL1X,TCF12,MMRN2,PAFAH1B1,ATP6V1A,TNXB,PPP2R2A,TMEM104,SPATS2,TM4SF19,ZNF827,BRE,CCDC50,FSIP2,VGF,SLC38A2,ADCK4,ITGAX,VCL,IPO11,PERP,COL5A2,TEX19,EIF3J,LGALS1,DLG4,ATP6V0A1,TOR1AIP2,KCNH3,STK10,HSD3B7,BTBD11,VDR,METTL6,POLR3E,ARNTL,ITGA2,ZNF436,TRAF3,FKBP5,NFRKB,RAB30,ATXN7L2,COMMD10,SSH2,SH2D3A,FAM46B,RTN4,RCAN1,AKT1S1,CSNK1A1,FAM49A,GIGYF2,PHLDA2,SFR1,TTC1,NEBL,ANXA7,PTRF,STC2,TMEM99,NLGN3,PCSK6,ARNTL2,FGF9,PPP1R9B,AP4S1,WDFY3,ZNF654,AGPAT4,C11orf49,ARHGAP32,GPNMB,RERE,YIF1A,NSD1,GADD45A,DSC2,STX1A,ARID3B,BCAS3,CSRNP1,SLCO5A1,SVIL,RBPJ,ITGB4,DDIT3 |
| 1.788e-02 | -4.02 | chondrosarcoma | COSMIC cancer mutations | chondrosarcoma | 1221 | 181 | 17775 | 2278 |
PHF3,CNTNAP3,NF1,KIF5A,MRPL10,NAT10,ZNF107,CSPP1,TTI1,PCDH7,SMARCB1,ZFHX3,THADA,ANKRD11,AP1M1,CHD2,ME1,MEIS3,FTSJ3,PRKACB,TBC1D8,CHD9,NRAS,BAZ2A,SLC38A1,KIF15,MCL1,LAMA2,KCNH2,DENND4A,FLVCR1,ZNF197,SLC7A1,TMEM132B,ZNF622,AHNAK,SUFU,TNFRSF1A,DNAH2,ZNF532,DMTF1,SYNPO,DCTN3,HERC2,C9orf78,CHST11,VTA1,RSF1,CDC73,ABCA7,MTUS1,IGF2BP3,RBM20,ELL,C6orf48,SIPA1L3,HVCN1,SCAF1,TIMELESS,CTR9,PNPLA3,PRMT5,NRIP1,FMNL2,TRA2A,XPO5,SETD2,RYR2,OBSCN,LIG4,MTR,ATP9B,DYNC1H1,GRIK4,EPRS,ASCC3,LRP1B,ATAD5,PALB2,FSCN1,KIAA0754,SDCCAG8,MED15,EXOC4,ZNF160,HK2,UMPS,VMA21,TCF12,TRPM2,DNM3,PCNT,ATP6V1A,NDUFAF2,HFM1,NTSR1,TNXB,MYH9,ZNF83,SSBP2,CORO6,SEMA6A,ABCA12,FSIP2,SNTG2,INTS12,TTC3,FHIT,CORO1A,AKNAD1,VCL,LYST,MAML3,KDM3B,WDR36,PHLDB2,KMT2D,COL5A2,PCNXL2,R3HDM1,METTL15,AKAP13,UBR4,VPS53,DHX57,PDE8B,RANBP2,KDM4B,HYAL3,ASTN2,ZNF236,WDR7,LARGE,ZNF436,PRRT3,FUS,FAHD1,MUTYH,YEATS2,METTL2B,BRAF,PDE4B,WDR37,RTN4,SEMA3E,LIAS,OPA1,CSNK1A1,GIGYF2,NEDD4,IQGAP2,TADA3,ZNF483,GART,SACS,DSG2,LTN1,GREB1,POLR1B,PLEKHG4,NAV3,DNMBP,DDX24,ADAMTSL3,ZC4H2,FERMT2,PACS1,ARHGEF12,R3HDM2,MEN1,ZNF407,SYMPK,YIF1A,SRCAP,HELZ,ORC5,APAF1,XPO6,MIPOL1,KDM4C,ANAPC4 |
| 1.791e-02 | -4.02 | regulation of mRNA export from nucleus | biological process | GO:0010793 | 5 | 3 | 16441 | 2138 |
SUPT6H,ZC3H3,SETD2 |
| 1.791e-02 | -4.02 | BMP signaling pathway involved in heart development | biological process | GO:0061312 | 5 | 3 | 16441 | 2138 |
MSX2,MSX1,BMP4 |
| 1.791e-02 | -4.02 | regulation of ribonucleoprotein complex localization | biological process | GO:2000197 | 5 | 3 | 16441 | 2138 |
SUPT6H,ZC3H3,SETD2 |
| 1.791e-02 | -4.02 | negative regulation of response to interferon-gamma | biological process | GO:0060331 | 5 | 3 | 16441 | 2138 |
PTPN2,PPARG,DNAJA3 |
| 1.791e-02 | -4.02 | negative regulation of centriole replication | biological process | GO:0046600 | 5 | 3 | 16441 | 2138 |
CHMP2A,BRCA1,TRIM37 |
| 1.791e-02 | -4.02 | protein repair | biological process | GO:0030091 | 5 | 3 | 16441 | 2138 |
MSRB3,MSRA,PCMT1 |
| 1.791e-02 | -4.02 | response to aluminum ion | biological process | GO:0010044 | 5 | 3 | 16441 | 2138 |
ALAD,LONP1,NT5E |
| 1.791e-02 | -4.02 | L-proline biosynthetic process | biological process | GO:0055129 | 5 | 3 | 16441 | 2138 |
ALDH18A1,PYCRL,PYCR1 |
| 1.791e-02 | -4.02 | response to cell cycle checkpoint signaling | biological process | GO:0072396 | 5 | 3 | 16441 | 2138 |
APAF1,SLX4,EME1 |
| 1.791e-02 | -4.02 | ribonucleoside monophosphate catabolic process | biological process | GO:0009158 | 5 | 3 | 16441 | 2138 |
HPRT1,AMPD3,NT5E |
| 1.791e-02 | -4.02 | negative regulation of interferon-gamma-mediated signaling pathway | biological process | GO:0060336 | 5 | 3 | 16441 | 2138 |
PTPN2,PPARG,DNAJA3 |
| 1.791e-02 | -4.02 | positive regulation of alkaline phosphatase activity | biological process | GO:0010694 | 5 | 3 | 16441 | 2138 |
SMAD3,PPARGC1B,MEF2C |
| 1.791e-02 | -4.02 | purine ribonucleoside monophosphate catabolic process | biological process | GO:0009169 | 5 | 3 | 16441 | 2138 |
HPRT1,AMPD3,NT5E |
| 1.791e-02 | -4.02 | regulation of transcription during mitosis | biological process | GO:0045896 | 5 | 3 | 16441 | 2138 |
SMARCA4,TCF7L1,SIRT7 |
| 1.791e-02 | -4.02 | response to DNA damage checkpoint signaling | biological process | GO:0072423 | 5 | 3 | 16441 | 2138 |
APAF1,SLX4,EME1 |
| 1.791e-02 | -4.02 | purine ribonucleoside salvage | biological process | GO:0006166 | 5 | 3 | 16441 | 2138 |
APRT,HPRT1,ADK |
| 1.791e-02 | -4.02 | His-Purkinje system development | biological process | GO:0003164 | 5 | 3 | 16441 | 2138 |
ID2,DSG2,TBX3 |
| 1.791e-02 | -4.02 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological process | GO:1903025 | 5 | 3 | 16441 | 2138 |
NSD1,ID1,DDIT3 |
| 1.791e-02 | -4.02 | response to DNA integrity checkpoint signaling | biological process | GO:0072402 | 5 | 3 | 16441 | 2138 |
APAF1,SLX4,EME1 |
| 1.791e-02 | -4.02 | NSUN2 (NOP2/Sun RNA methyltransferase family, member 2) | protein interactions | 54888 | 60 | 15 | 16036 | 2270 |
WDR74,HARS,COPS5,ACTR3,SIRT7,XPO5,TSN,RDX,RANGAP1,PUS1,FBL,AARS,DDX49,SH3GL1,RPA1 |
| 1.791e-02 | -4.02 | UBTF (upstream binding transcription factor, RNA polymerase I) | protein interactions | 7343 | 60 | 15 | 16036 | 2270 |
IRS1,UBTF,RRN3,CUL7,MYBBP1A,TAF1,POLR1A,CDK4,SIRT7,MAD1L1,CSNK2A1,RNF2,SERPINH1,ZMYM2,POLR1E |
| 1.791e-02 | -4.02 | XPO5 (exportin 5) | protein interactions | 57510 | 60 | 15 | 16036 | 2270 |
TTC1,SARS,P3H1,NEK6,FN1,DUS3L,HARS,UCHL5,MYC,SIRT7,RAN,ZNF346,NUP214,UBC,BAG1 |
| 1.791e-02 | -4.02 | PFN1 (profilin 1) | protein interactions | 5216 | 60 | 15 | 16036 | 2270 |
VIPR1,SRPRB,DBN1,CUL7,FN1,GPHN,TMSB10,UCHL5,FMNL1,SET,LIG4,ENAH,FUS,XPO6,ISG15 |
| 1.791e-02 | -4.02 | TLN1 (talin 1) | protein interactions | 7094 | 60 | 15 | 16036 | 2270 |
CUL7,PXN,TUBA1A,FN1,TXLNG,TRIP6,CC2D1B,SIRT7,WAC,SHMT2,PTK2,VCL,NMD3,TERF2,NUDC |
| 1.792e-02 | -4.02 | hydrolase activity | molecular function | GO:0016787 | 2416 | 350 | 16491 | 2164 |
PTP4A1,GGT1,CGN,GNB3,ADAM19,PRDX6,DCP1B,DDX19A,TUBE1,ADAMTS6,HLTF,NT5C3A,SYNJ1,ABHD6,AARS,RAC3,LPIN1,MMP7,FAAH2,CHD2,PPM1K,GNL3,PTPRM,EYA3,KIF15,DESI1,ABCC2,MCM2,DDX60,PLCXD2,GNAI1,DDX3X,DDAH2,SSU72,RAD18,CFD,XPNPEP1,DNAH2,DIRAS1,BLMH,PTPN14,EP400,DROSHA,LARS2,AK6,SIRT7,TATDN3,PLA2G12A,RSF1,PARN,CHD5,ABCA7,DDX56,ENTPD5,DHX37,USPL1,APLF,MCM5,ATIC,AGL,PPA1,ADARB1,GTF2H3,DDX28,EXOSC2,MYO10,POLA1,EIF4A2,RAP1B,PTPN12,USP10,PLCB1,ABCF1,USP46,ATP9B,DAGLA,CAT,DYNC1H1,ASCC3,TASP1,MTHFD2,ALKBH3,NSF,GPN1,SENP3,DPEP1,CNOT6,BPNT1,CNDP2,MACROD1,PLPP6,DNM3,TRPM2,ABCA3,DDX18,ATP6V1A,HFM1,OLA1,MYH9,ISG20L2,TUBB6,POP5,PTPRG,MCM9,HSPA1A,PDE3A,RPP30,CHD7,SLX4,ABCA12,ERI1,UCHL5,LPIN2,MMP14,NT5C,MSH4,PNPLA4,MGLL,MTHFD2L,ATP6AP1L,RFC4,PMS1,RFC3,STAMBP,MTIF2,ATP6V0A1,ADAM32,GNL1,NUDT15,DHX57,PDE8B,TAF2,ALKBH1,ACP1,MDN1,BRCC3,RAB30,VWA8,HMGA2,SSH2,C10orf2,KIF5C,MLH1,OPA1,RNASEH2B,GDPD5,INPP1,DCTPP1,PMPCA,ACOT11,NLGN3,DYNC2H1,EXOSC4,NT5M,LYPLA2,MBTPS2,DIS3L2,PFKFB4,DDHD1,APEX1,DDX24,USP42,APTX,PPIP5K2,GUF1,PDE3B,DDX49,MMAA,ANXA1,TOE1,SRCAP,DDX50,HELZ,PLPPR2,PTPN4,AEN,PGAM5,MTMR1,NUDT22,IMMP2L,ATRX,KIF5A,PTPRA,SIRT2,AHCYL2,EDC3,AMPD3,RAP1A,COPS4,LONRF2,DHX33,XRCC2,MYH3,HYAL1,JOSD1,RAN,OGG1,LONP1,TIMM50,PTPRK,CHD9,ABCC4,SIRT6,ITPA,SKIV2L2,KATNAL1,LVRN,GPCPD1,TSN,GDPD1,HSPA5,HDAC8,MTHFD1L,LSG1,PEX1,KIF16B,GLS,RHOU,CHD3,EEFSEC,RAD51B,ADAM9,DPP4,ABCC3,PPP3CC,EME1,CLU,TSEN2,NOCT,USP15,LDAH,PGPEP1,MCM6,PRSS3,FAN1,PCSK7,C11orf54,DNAH1,RHBDD1,ABCA5,PDE10A,GTF2H1,SYNJ2,PNPLA3,N4BP2,ATP6V0D1,CPSF3L,MTHFD1,NT5E,PDE4A,USP49,PSMA1,CORIN,DNAH14,POP1,FAM135A,DNAH17,RRAGA,PTRH2,DTD1,GGT7,PTP4A2,DDX10,PDE9A,USP7,CYLD,CEMIP,MYO7A,PPP2R2A,SMARCA4,ARSJ,PUDP,DDX60L,DHX35,CAD,IDI1,LYPLAL1,HIBCH,MYH15,FHIT,CPSF3,AHCYL1,GNG5,CASP10,HTRA2,SKIV2L,DDX41,TUBA1A,THSD4,RAB7A,NLN,EDEM2,ATP8B2,USP36,RAB10,RAD54B,ATP5D,EXO1,ZC3H12A,RBBP8,HYAL3,COPS5,ABHD3,DUSP19,SEPT5,USP11,FAHD1,MUTYH,YDJC,HM13,KLC4,AGO2,PDE4B,MAP1S,VARS,ATF7IP,GFM2,MAN1A1,PTPN2,DDX31,CD44,ERI3,PCSK6,TOP1,ADAMTSL3,SMARCAD1,ABCF2,DHX34,EXOG,PDE2A,RHOT2,EIF5B,NAPEPLD,NEU1,SMPDL3B,HSPA1B,ZRANB3,MFN2,DAGLB,ADAT2,AGTPBP1,MSH3,USP20,MYRF,PREPL,TATDN1,MMP16,KIF1B,NIT1,TRAPPC12 |
| 1.794e-02 | -4.02 | primary_central_nervous_system_lymphoma | COSMIC cancer mutations | primary_central_nervous_system_lymphoma | 723 | 112 | 17775 | 2278 |
GGT1,AMOTL1,CNTNAP3,CACNA1H,CSNK2A1,RIPK1,CSPP1,PTPRG,CORO6,COX10,AARS,DHX35,BIRC2,RPGRIP1L,KDM1A,AMBRA1,ZSCAN5A,DST,ZNF608,AMPD3,NRF1,MPHOSPH10,THADA,ZNHIT6,RNF111,ZNF142,TTC3,MSANTD2,LYST,CASP10,FAM184A,LAMA4,FLNC,RFC3,SSFA2,HARS,WLS,CPOX,LRRC8A,SGK2,KMT2C,KCNH2,FOXRED1,TMSB4X,UBR4,PDE8B,EPN2,AHNAK,TRRAP,EIF4ENIF1,ZNF333,ITGA2,ZNF236,TNFRSF1A,CSMD3,FIS1,NFRKB,WDR66,FAM118A,BLMH,SPOCK3,YEATS2,PARD3,CTU2,BANP,PRPF38B,ZNF786,MIF4GD,CHST11,FN1,ST6GAL1,DPF2,PRSS3,TCF3,PDE4B,FOXO3,POM121,MAD2L2,ABCA7,PRKCE,HIST2H3D,GTF3C3,ERRFI1,NRIP1,AKAP11,PABPC1,SAMD4A,MYB,LRRC20,LRRIQ1,RYR2,OBSCN,PRDM1,CORIN,LENG8,ANKRD20A4,FOXC1,SYMPK,DYNC1H1,RETSAT,RARS,VPS13C,LRP1B,FAM135A,FSCN1,PLPPR2,SLC16A1,MYOM2,ARHGAP12,SORCS2,NR2F2,MMP16 |
| 1.794e-02 | -4.02 | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma | 723 | 112 | 17775 | 2278 |
GGT1,AMOTL1,CNTNAP3,CACNA1H,CSNK2A1,RIPK1,CSPP1,PTPRG,CORO6,COX10,AARS,DHX35,BIRC2,RPGRIP1L,KDM1A,AMBRA1,ZSCAN5A,DST,ZNF608,AMPD3,NRF1,MPHOSPH10,THADA,ZNHIT6,RNF111,ZNF142,TTC3,MSANTD2,LYST,CASP10,FAM184A,LAMA4,FLNC,RFC3,SSFA2,HARS,WLS,CPOX,LRRC8A,SGK2,KMT2C,KCNH2,FOXRED1,TMSB4X,UBR4,PDE8B,EPN2,AHNAK,TRRAP,EIF4ENIF1,ZNF333,ITGA2,ZNF236,TNFRSF1A,CSMD3,FIS1,NFRKB,WDR66,FAM118A,BLMH,SPOCK3,YEATS2,PARD3,CTU2,BANP,PRPF38B,ZNF786,MIF4GD,CHST11,FN1,ST6GAL1,DPF2,PRSS3,TCF3,PDE4B,FOXO3,POM121,MAD2L2,ABCA7,PRKCE,HIST2H3D,GTF3C3,ERRFI1,NRIP1,AKAP11,PABPC1,SAMD4A,MYB,LRRC20,LRRIQ1,RYR2,OBSCN,PRDM1,CORIN,LENG8,ANKRD20A4,FOXC1,SYMPK,DYNC1H1,RETSAT,RARS,VPS13C,LRP1B,FAM135A,FSCN1,PLPPR2,SLC16A1,MYOM2,ARHGAP12,SORCS2,NR2F2,MMP16 |
| 1.796e-02 | -4.02 | CLASRP (CLK4-associating serine/arginine rich protein) | protein interactions | 11129 | 16 | 6 | 16036 | 2270 |
SMAD3,VDR,ATXN1,CDK6,TERF2,SRPK2 |
| 1.796e-02 | -4.02 | LCP1 (lymphocyte cytosolic protein 1 (L-plastin)) | protein interactions | 3936 | 16 | 6 | 16036 | 2270 |
RDX,CNDP2,FN1,ATXN2,SIRT7,GLYR1 |
| 1.796e-02 | -4.02 | IRF2BPL (interferon regulatory factor 2 binding protein-like) | protein interactions | 64207 | 16 | 6 | 16036 | 2270 |
HIBCH,FOSL2,NSF,NPM3,ETFB,FANCD2 |
| 1.796e-02 | -4.02 | CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4) | protein interactions | 131474 | 16 | 6 | 16036 | 2270 |
SENP3,TIMM10,SON,RHOT2,CIAPIN1,SURF1 |
| 1.796e-02 | -4.02 | SHPRH (SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase) | protein interactions | 257218 | 16 | 6 | 16036 | 2270 |
HLTF,RAD18,USP49,USP36,FDFT1,LPP |
| 1.796e-02 | -4.02 | HIST1H4B (histone cluster 1, H4b) | protein interactions | 8366 | 16 | 6 | 16036 | 2270 |
TERF2IP,CUL7,FN1,UCHL5,COPS5,CUL2 |
| 1.796e-02 | -4.02 | NDUFAB1 (NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa) | protein interactions | 4706 | 16 | 6 | 16036 | 2270 |
LYRM4,LYRM5,NT5C3A,LYRM2,SMYD3,LYRM7 |
| 1.796e-02 | -4.02 | NOL9 (nucleolar protein 9) | protein interactions | 79707 | 16 | 6 | 16036 | 2270 |
RNF2,AHNAK,BMI1,PELP1,SIRT7,WDR18 |
| 1.796e-02 | -4.02 | LOXL4 (lysyl oxidase-like 4) | protein interactions | 84171 | 16 | 6 | 16036 | 2270 |
SEPHS2,TRIP13,LONP1,KDM1A,EXOC6,CDC37 |
| 1.797e-02 | -4.02 | BRK | pfam domains | PF07533 | 5 | 3 | 16629 | 2165 |
SMARCA4,CHD7,CHD9 |
| 1.797e-02 | -4.02 | CobW_C | pfam domains | PF07683 | 5 | 3 | 16629 | 2165 |
CBWD1,CBWD6,CBWD5 |
| 1.797e-02 | -4.02 | Laminin_II | pfam domains | PF06009 | 5 | 3 | 16629 | 2165 |
LAMA4,LAMA2,LAMA5 |
| 1.797e-02 | -4.02 | WHIM3 | pfam domains | PF15614 | 5 | 3 | 16629 | 2165 |
BAZ1A,BAZ2B,BAZ2A |
| 1.797e-02 | -4.02 | FYRN | pfam domains | PF05964 | 5 | 3 | 16629 | 2165 |
KMT2D,KMT2C,KMT2A |
| 1.797e-02 | -4.02 | cobW | pfam domains | PF02492 | 5 | 3 | 16629 | 2165 |
CBWD1,CBWD6,CBWD5 |
| 1.797e-02 | -4.02 | DUF4704 | pfam domains | PF15787 | 5 | 3 | 16629 | 2165 |
NBEA,NBEAL1,WDFY3 |
| 1.797e-02 | -4.02 | FYRC | pfam domains | PF05965 | 5 | 3 | 16629 | 2165 |
KMT2D,KMT2C,KMT2A |
| 1.797e-02 | -4.02 | Laminin_I | pfam domains | PF06008 | 5 | 3 | 16629 | 2165 |
LAMA4,LAMA2,LAMA5 |
| 1.797e-02 | -4.02 | WHIM1 | pfam domains | PF15612 | 5 | 3 | 16629 | 2165 |
BAZ1A,RSF1,BAZ2A |
| 1.797e-02 | -4.02 | BCDHK_Adom3 | pfam domains | PF10436 | 5 | 3 | 16629 | 2165 |
BCKDK,PDK1,PDK4 |
| 1.797e-02 | -4.02 | zf-C5HC2 | pfam domains | PF02928 | 5 | 3 | 16629 | 2165 |
KDM5C,KDM5B,KDM5A |
| 1.798e-02 | -4.02 | negative regulation of blood vessel endothelial cell migration | biological process | GO:0043537 | 22 | 7 | 16441 | 2138 |
DLL4,MAP2K5,HRG,MMRN2,FGF2,KLF4,ANGPT2 |
| 1.798e-02 | -4.02 | snRNA processing | biological process | GO:0016180 | 22 | 7 | 16441 | 2138 |
INTS12,EXOSC2,EXOSC4,INTS7,INTS5,CPSF3L,INTS9 |
| 1.798e-02 | -4.02 | blastocyst growth | biological process | GO:0001832 | 22 | 7 | 16441 | 2138 |
CTR9,BRCA2,BRD4,PALB2,SBDS,RAD51B,PRPF19 |
| 1.799e-02 | -4.02 | - | gene3d domains | 3.40.50.2020 | 12 | 5 | 9988 | 1398 |
UMPS,APRT,HPRT1,PPAT,PRPS1 |
| 1.799e-02 | -4.02 | RARA (retinoic acid receptor, alpha) | protein interactions | 5914 | 121 | 26 | 16036 | 2270 |
USP7,PRAME,NCOR2,RFC4,FN1,PRDX6,FOXO1,NPAS2,KDM5A,SMARCD3,POU2F1,ARID1A,PRKCA,SKI,TADA3,SNW1,NSD1,HR,UBE3A,GADD45A,SPEN,ARNTL,NCOR1,RUNX1,NRIP1,BAG1 |
| 1.805e-02 | -4.01 | ARRB2 (arrestin, beta 2) | protein interactions | 409 | 338 | 62 | 16036 | 2270 |
POLR1A,NTSR1,MYH9,CSNK2A1,WDR26,AP1B1,UBR5,HIST2H2AB,PABPC4,NDUFS7,NEDD4,NOP56,STC2,IGF2BP1,POLR1B,MAP3K14,FBL,YBX3,PRMT5,SRRM2,PABPC1,HNRNPM,SERBP1,TMPO,SPTAN1,SRPK2,DBN1,ARHGAP17,TUBA1A,LIMA1,CDK4,ARRDC3,HSPA5,C5AR1,RANGAP1,VIM,ARHGEF12,DKC1,ARRDC4,SLC9A5,UBC,CLNS1A,HSPA1B,RPA1,BSN,PES1,DYNC1H1,DDX3X,ARHGAP21,CAMK2D,RPL28,KPNA3,HNRNPR,H2AFX,PRPF4,TRAF3,ZRANB2,ANXA2,POLR1C,TBXA2R,NOLC1,MAP2K4 |
| 1.809e-02 | -4.01 | genital_tract-extragonadal-germ_cell_tumour-seminoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-seminoma | 66 | 15 | 17775 | 2278 |
LAMA4,FLNC,TTLL5,BRAF,NRAS,HLCS,NF1,TNFRSF21,SOCS4,PRICKLE2,SON,NLE1,DNAH1,SPTAN1,ATP9B |
| 1.810e-02 | -4.01 | Annexin_repeat | interpro domains | IPR018502 | 13 | 5 | 18293 | 2341 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 1.810e-02 | -4.01 | Annexin_repeat_CS | interpro domains | IPR018252 | 13 | 5 | 18293 | 2341 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 1.810e-02 | -4.01 | Annexin | interpro domains | IPR001464 | 13 | 5 | 18293 | 2341 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 1.816e-02 | -4.01 | V$ARNT_02 | MSigDB lists | V$ARNT_02 | 237 | 42 | 17758 | 2279 |
OLFM2,ANKRD17,ATP6V1A,NFX1,ATF7IP,GYG1,UBR5,GIGYF2,IGF2BP3,PRKCE,SPG21,SLC38A5,ATG3,GLYR1,VGF,DCTN4,ACAP3,GTF2H1,JOSD1,CEP63,FBXL19,LONP1,BDNF,ATF4,ANAPC13,APEX1,GMFB,CPT1A,UBR4,PES1,CAMK2D,SYNCRIP,ZBTB8OS,HIF1A,HSPBAP1,VPS37B,SLCO5A1,DLX2,EME1,YEATS2,RAB30,SLC43A1 |
| 1.820e-02 | -4.01 | endometrium-ovary-endometriosis | COSMIC cancer mutations | endometrium-ovary-endometriosis | 13 | 5 | 17775 | 2278 |
ARID1A,BRAF,BRCA1,NRAS,MAP2K4 |
| 1.822e-02 | -4.01 | cell projection assembly | biological process | GO:0030031 | 267 | 47 | 16441 | 2138 |
TNIK,DNM3,MINK1,IFT57,PCNT,CELSR3,OPHN1,MKS1,ARFIP2,CEP126,PIBF1,RAC3,DNAH1,LPAR3,RPGRIP1L,ABL2,CEP164,RAP1A,CEP290,CCDC40,RDX,DYNC2H1,VCL,ATP6V0D1,PPP1R9B,TTLL5,CEP83,PXN,WDPCP,RAP1B,TMEM216,KIAA0586,CCDC113,ONECUT2,CCDC28B,ARMC4,IFT81,TMEM237,WDR35,FSCN1,E2F4,ARL13B,IFT140,BBIP1,ITGB4,FNBP1L,LAMA5 |
| 1.825e-02 | -4.00 | regulation of histone H3-K4 methylation | biological process | GO:0051569 | 27 | 8 | 16441 | 2138 |
SNW1,WDR61,CTR9,BRCA1,BCOR,KMT2A,KDM1A,MYB |
| 1.825e-02 | -4.00 | telomere maintenance via recombination | biological process | GO:0000722 | 27 | 8 | 16441 | 2138 |
RFC4,RFC3,POLE2,PRIM2,APEX1,POLA1,NSMCE2,RPA1 |
| 1.825e-02 | -4.00 | regulation of hormone metabolic process | biological process | GO:0032350 | 27 | 8 | 16441 | 2138 |
TRERF1,HIF1A,KCNMA1,STC2,BMP6,TCF7L2,KDM1A,PDE8B |
| 1.825e-02 | -4.00 | cell fate commitment involved in formation of primary germ layer | biological process | GO:0060795 | 27 | 8 | 16441 | 2138 |
PAF1,GATA6,KLF4,PAX2,CTR9,TRIM15,BMP4,CDC73 |
| 1.826e-02 | -4.00 | regulation of response to cytokine stimulus | biological process | GO:0060759 | 144 | 28 | 16441 | 2138 |
ZNF675,RBCK1,MAP2K5,CYLD,IFNGR2,PAFAH1B1,PPARG,RIPK1,GAS6,CAV1,NOL3,UBE2K,BIRC2,HSPA1A,UBC,HSPA1B,PTPN2,ECM1,PXDN,SOCS1,HIF1A,LSM14A,DNAJA3,KLF4,IRAK2,IKBKB,TNFRSF1A,CDC37 |
| 1.826e-02 | -4.00 | regulation of chromatin organization | biological process | GO:1902275 | 144 | 28 | 16441 | 2138 |
WDR61,PAXBP1,SUPT6H,KDM5A,CAMK1,MAP1S,BCOR,BRCA1,SETD7,RPS6KA5,UBR5,KDM1A,SKI,SNCA,SMARCB1,PAF1,RNF40,TADA3,SNW1,NSD1,CAMK2D,CDK9,SET,ATG7,CTR9,NCOR1,KMT2A,MYB |
| 1.828e-02 | -4.00 | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | 191 | 35 | 17758 | 2279 |
VIPR1,SPRED2,DLL4,CLK1,IGF2BP2,PDCD7,RNASEH2B,GBF1,CUTC,FAM49A,SURF2,NSRP1,RASSF3,MYC,DSG2,METTL8,GPATCH1,GEMIN4,CD44,AHCYL1,ACSL5,C2orf76,SETD2,C8orf33,GUF1,TMEM186,TSR1,PDLIM1,ARL4A,DPP4,SQLE,CDKAL1,C7orf50,FAHD1,PRKAR2A |
| 1.828e-02 | -4.00 | GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP | 191 | 35 | 17758 | 2279 |
TCF12,MCM10,SHQ1,TRIP6,PTPRA,DPM3,UBL5,ADH5,TTC1,SUV39H2,S100A10,PPID,ZNHIT6,ATIC,PIGG,BCAP29,AHCYL1,TSPAN14,SIK3,MIOS,GLTSCR2,TMEM126B,ARID5B,EHBP1,CLNS1A,SLC39A14,HLA-DMA,TASP1,CUL2,ITGA2,RRAGA,SIL1,CDKAL1,ACP1,CEP170 |
| 1.828e-02 | -4.00 | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | 191 | 35 | 17758 | 2279 |
SPRED2,BRAF,SLK,DCP1B,ACTR3,MYH9,CSPP1,MCM9,SCAF8,SFI1,TADA3,TBC1D22A,CORO1A,FHIT,MAP3K14,CNOT4,PPM1K,DIS3L2,ZNF646,ZFYVE1,C19orf43,NFIA,PEAR1,POLG2,POLR2A,ARPC3,DNTTIP1,TRRAP,SUFU,GADD45A,CCNT1,AGTPBP1,HIPK2,PQBP1,ASB3 |
| 1.828e-02 | -4.00 | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | 191 | 35 | 17758 | 2279 |
FEM1C,CDC42EP2,SPRYD7,ID2,FOSL2,HSPA1A,SBDS,NAMPT,ABL2,MYC,SLC38A2,RNF2,ETF1,KDM6B,AEBP2,TRIM13,LIMA1,ANKRD33B,JMJD1C,KIAA0586,MCL1,CAV1,KLF6,ARL5B,HERPUD1,ARIH2,ISG15,HSPA1B,ZC3H12A,ZNF622,ZNF81,CSRNP1,HK2,SRFBP1,ZBTB11 |
| 1.828e-02 | -4.00 | GSE17721_LPS_VS_POLYIC_2H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_2H_BMDM_DN | 191 | 35 | 17758 | 2279 |
ASH1L,FEZ2,HES6,TTI1,FAM8A1,ABL1,HVCN1,FGGY,COPS3,ZNF148,RAN,LYRM5,KDM5B,SIGMAR1,MANBAL,TBXAS1,TOP3A,RAP1GDS1,MCM2,SOX4,C8orf33,C1orf174,DHX57,MGAT2,IREB2,KLF4,SPEN,POLR3E,RIOK3,AEN,USP20,ZFP90,MED20,FAM118A,NIT1 |
| 1.828e-02 | -4.00 | GSE3982_DC_VS_TH2_DN | MSigDB lists | GSE3982_DC_VS_TH2_DN | 191 | 35 | 17758 | 2279 |
DDX18,COX10,PDCD5,HDDC2,SOCS1,PMAIP1,DSG2,KDELC1,ANKRD11,ZNF142,HIRIP3,ZEB1,RAN,TRIP13,PERP,NT5E,SF3A1,MYB,RFC4,RFC3,GINS3,HARS,TRA2A,ARID5B,KIF15,MARCKSL1,RYR2,ZDHHC14,SLC39A14,TRMT5,FTSJ1,MDN1,CCNB1IP1,USP11,TESC |
| 1.829e-02 | -4.00 | RATTENBACHER_BOUND_BY_CELF1 | MSigDB lists | RATTENBACHER_BOUND_BY_CELF1 | 386 | 64 | 17758 | 2279 |
SYT17,PPARGC1B,CERS5,CSPP1,SPATS2,SPATS2L,SLC25A44,FOSL2,C15orf40,NBEA,ADCK4,B3GNTL1,CDK12,KAT8,CHD9,LRRC8A,MCL1,TBC1D16,SKIL,MSRA,TMCO1,IKZF4,METTL6,SOCS4,PPP3CC,NFASC,LPP,PRPF38B,MAP3K13,RFX1,PSMF1,MBNL1,MAD2L2,PSMG4,CACNB2,UNC13A,PIGG,GTF2H1,ALDH18A1,TTC17,FMNL2,ATP6V0D1,NAV3,MSI2,RANBP6,KIAA1143,RREB1,PRIM2,CLYBL,PRDM16,MARS,RABAC1,NAPEPLD,VAC14,PGD,NSD1,INF2,GRIK4,TTC38,ZCCHC6,RNF138,TBL1X,GGT7,MMP16 |
| 1.829e-02 | -4.00 | HOXA9_DN.V1_DN | MSigDB lists | HOXA9_DN.V1_DN | 178 | 33 | 17758 | 2279 |
SERINC5,MPI,MCM10,EGR1,LPCAT3,SLC29A1,BHLHE40,STAM,TMCO6,METTL16,EXOC1,DCTN4,TOMM34,SLC25A1,HMGCR,FADS1,PRIM2,GINS3,PDK1,SLC38A1,ELOVL6,MEN1,ECH1,LSS,TRIB3,BRCA2,INTS9,SQLE,ALKBH1,FKBP5,MACROD1,TBXA2R,DHCR7 |
| 1.830e-02 | -4.00 | GTTAAAG,MIR-302B | MSigDB lists | GTTAAAG,MIR-302B | 66 | 15 | 17758 | 2279 |
SMAD3,RANBP2,SRSF2,KPNA3,KHDRBS1,ANK2,KCNMA1,ARNTL,PURB,ATXN1,TM4SF19,NRP1,SYNJ1,LCLAT1,LPIN1 |
| 1.830e-02 | -4.00 | V$STAT1_01 | MSigDB lists | V$STAT1_01 | 66 | 15 | 17758 | 2279 |
CEP164,SCAMP3,SLC38A5,UBR1,HNRNPR,IFT43,SET,CCDC85B,TNPO3,TXN2,PARN,ANKS1A,GABPB2,RAB10,VPS53 |
| 1.831e-02 | -4.00 | INTEGRATOR_COMPLEX | MSigDB lists | INTEGRATOR_COMPLEX | 13 | 5 | 17758 | 2279 |
INTS12,INTS7,INTS5,CPSF3L,INTS9 |
| 1.831e-02 | -4.00 | N_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | N_METHYLTRANSFERASE_ACTIVITY | 13 | 5 | 17758 | 2279 |
NSD1,SUV39H2,RNMT,PEMT,EHMT1 |
| 1.831e-02 | -4.00 | IVANOV_MUTATED_IN_COLON_CANCER | MSigDB lists | IVANOV_MUTATED_IN_COLON_CANCER | 13 | 5 | 17758 | 2279 |
MAP1S,LTN1,RNF43,NCOR1,MSH3 |
| 1.831e-02 | -4.00 | INAMURA_LUNG_CANCER_SCC_DN | MSigDB lists | INAMURA_LUNG_CANCER_SCC_DN | 13 | 5 | 17758 | 2279 |
ADARB1,PHACTR2,CAV1,ADAMTSL3,NR2F1 |
| 1.836e-02 | -4.00 | PCGF3 (polycomb group ring finger 3) | protein interactions | 10336 | 25 | 8 | 16036 | 2270 |
PHC2,USP7,CSNK2A1,RNF2,BCOR,BMI1,RING1,MGA |
| 1.836e-02 | -4.00 | MSX2 (msh homeobox 2) | protein interactions | 4488 | 25 | 8 | 16036 | 2270 |
ZBTB17,MSX2,POLR3D,MSX1,PPARG,SPEN,ATXN1,DLX2 |
| 1.836e-02 | -4.00 | sodium channel inhibitor activity | molecular function | GO:0019871 | 5 | 3 | 16491 | 2164 |
CAMK2D,SCN1B,NEDD4 |
| 1.836e-02 | -4.00 | U4 snRNA binding | molecular function | GO:0030621 | 5 | 3 | 16491 | 2164 |
PRPF4,SNU13,PRPF31 |
| 1.836e-02 | -4.00 | TFIID-class transcription factor binding | molecular function | GO:0001094 | 5 | 3 | 16491 | 2164 |
FBL,NOP58,ZNHIT6 |
| 1.836e-02 | -4.00 | 1-acylglycerophosphocholine O-acyltransferase activity | molecular function | GO:0047184 | 5 | 3 | 16491 | 2164 |
LPCAT3,LPCAT1,LPCAT2 |
| 1.836e-02 | -4.00 | Y-form DNA binding | molecular function | GO:0000403 | 5 | 3 | 16491 | 2164 |
RAD18,MEN1,MSH3 |
| 1.841e-02 | -3.99 | face | COSMIC cancer mutations | face | 2212 | 315 | 17775 | 2278 |
PTP4A1,GGT1,MYCBP2,ADAM19,DPH1,MKS1,SBF2,HLTF,HMOX2,NUP160,SYNJ1,LPIN1,NOS1AP,EXOC1,PDZD2,NEK6,ZFHX3,PDS5B,WIZ,SRRM2,SPAG6,ZNF646,NRAS,OSBP2,LIMA1,PTPRM,ALDH1L2,EHMT1,TCEB3,WDHD1,AKAP12,ABCC2,SON,AHNAK,TRRAP,LSM14A,SYNGR2,VPS13D,DNAH2,NRP1,TNFRSF10D,WDR66,PTPN14,TNNC1,EP400,CELSR1,ZHX3,TRIO,CCDC47,PITPNM1,IGF2BP3,SLC38A5,USPL1,INTS7,PIGG,IGF2BP1,CALN1,ZNF518B,AGL,CAV2,PABPC1,ANGPT2,GATAD2B,KCNQ3,RB1CC1,PRDM16,AOC2,PTPN12,PLCB1,CPT1A,ONECUT2,ANGPTL4,ABCF1,DYNC1H1,ZNF425,VPS13C,LRP1B,KIDINS220,VCAN,SPEN,ZZEF1,ZBTB12,BIVM,WDR33,PDLIM5,SMYD3,COG5,RTTN,PTCD2,ABCA3,NPAS2,RIBC2,HFM1,ACTR3,KIAA0232,OLA1,RING1,RPGRIP1L,PDE3A,NOP56,SLX4,PPID,GLYR1,MMP14,INTS12,TTC3,SSBP1,MSH4,KMT2A,ZC3H3,DENND1A,ARHGEF10,SLCO6A1,LRRC8A,ERC1,FGFR1,PDE8B,VDR,IQCH,KDM4B,ASTN2,NSMCE2,IFT140,MDN1,PDCD11,LAMA5,YEATS2,CATSPERG,MID1,LRCH1,BRAF,SESTD1,TCF3,BHLHE40,NEDD4,KRI1,TTLL11,TADA3,ABL1,ZNF239,ZNF483,RGS17,NEBL,TAF3,LRP2BP,NISCH,LTN1,UPF2,ERRFI1,LARP4B,NAV3,ULBP1,FAM120B,TMC7,TTPAL,TSHZ1,TTLL5,TBRG4,BMS1,UBC,YIF1A,SRCAP,IREB2,HELZ,ATM,SVIL,MYOM2,PSAP,GPATCH4,MVK,TRIM16,UBN1,NF1,POLR1A,TFIP11,MFGE8,TRPM6,RNF43,COX10,SMARCB1,RTN1,DST,ZNF804A,GPR87,ZEB1,KIAA0922,POLR3B,SLC27A5,ZNF3,TRIP13,PTPRK,VPS13B,FLNC,LAMA4,FMNL3,GPM6A,SLC3A2,ABCC4,PPARG,ANK2,NOL6,KCNH2,KMT2C,ST3GAL5,BSN,PEX1,TMEM132B,EIF4ENIF1,GATA6,SUFU,TP53BP1,CHD3,ADAM9,DPP4,CSMD3,MAGI1,SLC12A7,OXNAD1,ZCCHC8,ITFG1,MED13L,BARX2,QSER1,DOPEY1,TOX4,ABCA5,VPS72,PPIL2,CCDC112,CCDC167,ZCCHC7,N4BP2,NT5E,MTHFD1,MSI2,RANBP6,LAMC1,IFT43,JMJD1C,SETD2,TBXAS1,UTP15,ZNFX1,PRDM1,CORIN,GRIK4,BICD1,HK2,EXOC4,SLC16A1,PPP1R12B,USP7,CYLD,ASH1L,OLFM2,PCNT,PAPD4,ARID2,TMEM183A,ARSJ,DENND3,PIBF1,RADIL,PPP1R9A,ZC3H13,VPS18,BRE,CAMTA2,PPFIBP1,CCDC40,RNF2,ITGAX,MET,GNG5,C6orf89,HTRA2,ACSL5,COL5A2,BTBD11,ZC3H12A,RANBP2,ZNF557,PRRT3,NFRKB,PARD3,ZNF507,ATXN7L2,KLHL24,DMGDH,HM13,C17orf80,PDE4B,LETMD1,MAP1S,IGF2BP2,IQGAP2,SACS,SCN1B,SEC24C,PCK2,KDM6B,DNMBP,ADAMTSL3,LRRIQ1,C11orf49,PALLD,SMPDL3B,POLR3A,RERE,MFN2,GPC2,TAF4,CSRNP1,BCAS3,PREPL |
| 1.841e-02 | -3.99 | response to calcium ion | biological process | GO:0051592 | 113 | 23 | 16441 | 2138 |
TTN,BRAF,ACTG1,KCNMA1,SLC25A12,RYR2,CAV1,SYT1,NEDD4,S100A16,GIPR,SEC31A,CAMK2D,ANXA7,D2HGDH,ANXA5,ADAM9,DPEP1,FUS,CPNE7,AHCYL1,SLC25A23,MEF2C |
| 1.844e-02 | -3.99 | COPS6 (COP9 signalosome subunit 6) | protein interactions | 10980 | 295 | 55 | 16036 | 2270 |
KLHL24,KCTD7,USP7,CUL4A,BTBD2,RHOBTB1,RIBC2,SLC2A1,KLHL18,BTBD9,RSF1,HMOX2,COA1,ZMAT2,HSPA1A,ANXA7,COPS4,S100A10,COPS3,COPS7B,RPL22L1,PABPC1,DIS3L2,LAMA4,FBXO17,FBXW4,CDK4,HSPA5,KSR2,TOR1AIP2,VIM,MAP7D1,IMPDH2,EHBP1,C1orf174,UBC,HSPA1B,RAD54B,ANXA1,DDX3X,DLEU1,PWP1,KLHL22,TRIB3,FBXO21,SYNCRIP,HNRNPH3,COPS5,MBTD1,CUL2,RNF138,PPP1R12B,FUS,PSAP,COPS6 |
| 1.853e-02 | -3.99 | MATTIOLI_MGUS_VS_PCL | MSigDB lists | MATTIOLI_MGUS_VS_PCL | 96 | 20 | 17758 | 2279 |
EXOSC2,MCM6,SHQ1,ITPA,WDR18,ACTR3,OPHN1,TBRG4,CSNK2A1,SMARCA4,MCM2,SSR4,CDC73,CAD,INTS7,MCM5,EXOSC4,RAN,CORO1A,SAP30 |
| 1.853e-02 | -3.99 | LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | LIPID_BIOSYNTHETIC_PROCESS | 96 | 20 | 17758 | 2279 |
FADS1,MVK,CERS5,PIGH,DPM3,BRCA1,BMP6,HSD3B7,PEX7,IDI1,PI4KB,PEMT,FDPS,PIGG,LARGE,PTGS1,PNPLA3,LPCAT1,DHCR7,PDSS2 |
| 1.853e-02 | -3.99 | Viral RNP Complexes in the Host Cell Nucleus | REACTOME pathways | R-HSA-168330 | 2 | 2 | 8202 | 1117 |
HSPA1A,HSPA1B |
| 1.853e-02 | -3.99 | Abasic sugar-phosphate removal via the single-nucleotide replacement pathway | REACTOME pathways | R-HSA-73930 | 2 | 2 | 8202 | 1117 |
POLB,APEX1 |
| 1.853e-02 | -3.99 | Interactions of Tat with host cellular proteins | REACTOME pathways | R-HSA-176034 | 2 | 2 | 8202 | 1117 |
CCNT1,CDK9 |
| 1.855e-02 | -3.99 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 352 | 59 | 17758 | 2279 |
IMMP2L,VMA21,MYCBP2,ID1,FEM1C,CCDC58,EGR1,RHOBTB1,ST6GAL1,MFGE8,SMAD7,HLTF,NOL3,BHLHE40,TMCO6,LPIN1,NDUFB3,DECR1,IDI1,RABGAP1L,IPP,VAPB,ERRFI1,AMOT,COQ3,TMLHE,KAT8,KDM6B,RANBP6,GCNT2,COL5A2,PDK1,SKAP2,CLYBL,C2orf76,WDPCP,ARID5B,METTL15,TOR1AIP2,SGK2,CPT1A,KLF6,UBC,S100A16,ZRANB3,SKIL,CAT,LSS,GSTO2,NSMCE1,IRAK2,SNX24,PTRH2,SIL1,ARHGAP12,RBPJ,CLU,MUTYH,NIT1 |
| 1.855e-02 | -3.99 | pancreas-other-adenoma | COSMIC cancer mutations | pancreas-other-adenoma | 231 | 41 | 17775 | 2278 |
GGT1,NCOR2,BRAF,PRKCSH,ATRX,KLC4,SBF2,RNF43,PRKCA,IKBKAP,UBR5,ANAPC1,ESAM,ANKRD11,CTR9,SSBP1,KMT2A,MAP3K12,CNTNAP3B,NAV3,SIK3,NRAS,KCNQ3,ADAMTSL3,RFX2,SCMH1,EFHC1,SGK2,ANKRD20A4,ERC1,MFN2,GRIK4,ATAD5,SLC30A3,TRRAP,TP53BP1,CHD3,ASTN2,KLF4,USP11,DDX10 |
| 1.858e-02 | -3.99 | protein N-terminus binding | molecular function | GO:0047485 | 100 | 21 | 16491 | 2164 |
GTF2H3,NCOR2,ID1,NTSR1,MYO7A,CSNK2A1,SMARCA4,APTX,MEN1,BIRC2,SNCA,SMARCC1,STX1A,ACOX1,DCTN4,UNC13A,EXOC4,ATM,RBPJ,SRRM2,PDLIM5 |
| 1.859e-02 | -3.99 | V$WHN_B | MSigDB lists | V$WHN_B | 244 | 43 | 17758 | 2279 |
BANP,CHST11,DLL4,JUP,NF1,ANKRD17,ZBTB37,DBF4,OPHN1,ID2,RNF43,BHLHE40,SYNJ1,UBR5,MBNL1,PCDH7,SLC30A7,CEP164,JAG1,PHF5A,UCHL5,STC2,SDCBP2,TOP1,BDNF,ELOVL6,GALK2,POLR2A,CXADR,YTHDF2,LRP1B,NSF,HNRNPH3,HERC1,METTL6,TBX3,ZBTB12,HOXA3,PRPF4,GREB1L,NOLC1,ZBTB11,TROVE2 |
| 1.861e-02 | -3.98 | negative regulation of cellular component organization | biological process | GO:0051129 | 574 | 92 | 16441 | 2138 |
CHMP2A,DNM3,ID1,FEZ2,PAFAH1B1,C16orf45,CSNK2A1,BCOR,SIRT2,BIRC2,SEMA6A,UBR5,HSPA1A,KDM1A,SBDS,SKI,TOM1L1,SMARCB1,TERF2IP,ANAPC1,LYPLAL1,ACD,DNAJB6,IKBKB,ANAPC11,ANAPC10,MMP14,MAD1L1,TTC3,CORO1A,HRG,FXN,CARM1,PHLDB2,EVL,LIMA1,LGALS1,GMFB,DLG4,VIM,SEMA3F,BRCA1,CAV1,SNCA,DDX3X,CDC16,TOM1L2,INSIG1,ATG7,DPP4,SEMA3C,CLU,ANXA2,NRP1,MID1,DNAJA4,SUPT6H,SMAD7,PID1,RTN4,SEMA3E,OPA1,NOL3,MAD2L2,SACS,ASAP1,ATXN2,TRIAP1,SEMA3D,RDX,NLGN3,LRSAM1,DMRT1,TERF2,SPTAN1,IFRD1,SYNGAP1,KDM5A,RAP1GAP2,TEX14,PTK2,TRIM37,UBE2E1,HSPA1B,DKK1,KLHL22,PMEPA1,SET,BCAS3,ATM,BMP4,ANAPC4 |
| 1.861e-02 | -3.98 | DITTMER_PTHLH_TARGETS_DN | MSigDB lists | DITTMER_PTHLH_TARGETS_DN | 72 | 16 | 17758 | 2279 |
SEC24A,CUL4A,MINK1,ACTG1,MYH9,FERMT2,PTK2,NDUFB3,RPP30,GLS,UBAP2,MCAM,SPEN,FAT1,TIMELESS,SAP30 |
| 1.861e-02 | -3.98 | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | 72 | 16 | 17758 | 2279 |
VOPP1,GPHN,TFPI,ZFP14,OBSCN,ATXN1,ENAH,RNF43,BHLHE40,PIK3CB,ACOXL,ZNF827,ASNS,NRIP1,CDK6,RAB30 |
| 1.862e-02 | -3.98 | KH_TYPE_1 | prosite domains | PS50084 | 33 | 9 | 11866 | 1504 |
ASCC1,NOVA2,ANKRD17,KHDRBS1,MEX3A,IGF2BP2,MEX3B,IGF2BP1,IGF2BP3 |
| 1.864e-02 | -3.98 | cellular response to extracellular stimulus | biological process | GO:0031668 | 176 | 33 | 16441 | 2138 |
CYP24A1,FOXO1,PDK4,SLC2A1,PIK3R4,ATG2B,GAS6,SIRT2,WNT2B,NPRL2,ASNS,SREBF2,PMAIP1,SEH1L,FADS1,PPP1R9B,ATF4,MIOS,PPARG,UPP1,HSPA5,LDHA,ATG12,CAV1,TCF7L2,VDR,MYBBP1A,ADNP,RRAGA,ATG7,EIF2S1,TXN2,TNRC6A |
| 1.865e-02 | -3.98 | Metabolite levels(PMID:20037589) | GWAS genes | Metabolite levels(PMID:20037589) | 4 | 3 | 2389 | 419 |
ACADS,FADS1,PPID |
| 1.865e-02 | -3.98 | Insulin-like growth factors(PMID:21216879) | GWAS genes | Insulin-like growth factors(PMID:21216879) | 4 | 3 | 2389 | 419 |
SORCS2,FOXO3,SPOCK2 |
| 1.865e-02 | -3.98 | Eosinophil counts(PMID:19198610) | GWAS genes | Eosinophil counts(PMID:19198610) | 4 | 3 | 2389 | 419 |
SH2B3,WDR36,TNXB |
| 1.865e-02 | -3.98 | Body mass index(PMID:22344219) | GWAS genes | Body mass index(PMID:22344219) | 4 | 3 | 2389 | 419 |
CDKAL1,MAP2K5,GIPR |
| 1.865e-02 | -3.98 | Aortic root size(PMID:21223598) | GWAS genes | Aortic root size(PMID:21223598) | 4 | 3 | 2389 | 419 |
CRCP,KCTD7,FHIT |
| 1.865e-02 | -3.98 | VAV2 (vav 2 guanine nucleotide exchange factor) | protein interactions | 7410 | 71 | 17 | 16036 | 2270 |
TTN,BIRC6,SF3A3,CAV1,POGZ,TOM1L1,SMAD3,TPD52L2,SNW1,SOCS1,CRCP,CD44,PNMA1,CEP170,SERBP1,IPO4,SRPK2 |
| 1.865e-02 | -3.98 | ABI2 (abl-interactor 2) | protein interactions | 10152 | 71 | 17 | 16036 | 2270 |
KRT20,ADAM19,DTNB,TRIP6,CCDC53,TFIP11,KHDRBS1,PCMT1,ENAH,ARHGAP32,EIF3H,ABL1,SNAP23,SHMT2,TPM1,VCL,CDK6 |
| 1.867e-02 | -3.98 | MCOLN3 (mucolipin 3) | protein interactions | 55283 | 55 | 14 | 16036 | 2270 |
DAGLA,RETSAT,ABCA3,TMEM219,TMEM177,ST7L,RNF130,KIAA0922,TTC17,ATP8B2,COA1,TMEM206,RDH11,SRPK2 |
| 1.867e-02 | -3.98 | RAB5C (RAB5C, member RAS oncogene family) | protein interactions | 5878 | 55 | 14 | 16036 | 2270 |
RAP1A,CUL7,RBSN,FN1,RAB7A,LGALS1,RAP1B,LAMTOR3,LDHA,RABAC1,EEA1,SGSM3,RAB10,RPA1 |
| 1.867e-02 | -3.98 | P3H1 (prolyl 3-hydroxylase 1) | protein interactions | 64175 | 55 | 14 | 16036 | 2270 |
UBE3A,SURF2,ALAD,MYC,XPO5,TSN,H2AFX,GPN1,PUS1,ZNF397,LRSAM1,SRP14,TOM1L1,LPP |
| 1.867e-02 | -3.98 | mucinous | COSMIC cancer mutations | mucinous | 38 | 10 | 17775 | 2278 |
BRCA2,SRSF2,BRAF,NRAS,RNF43,BRCA1,ARID1A,MET,MAP2K4,FGFR1 |
| 1.870e-02 | -3.98 | MoCF_biosynth | smart domains | SM00852 | 2 | 2 | 9131 | 1249 |
FLAD1,GPHN |
| 1.870e-02 | -3.98 | AARP2CN | smart domains | SM00785 | 2 | 2 | 9131 | 1249 |
BMS1,TSR1 |
| 1.870e-02 | -3.98 | FABD | smart domains | SM00808 | 2 | 2 | 9131 | 1249 |
ABL1,ABL2 |
| 1.870e-02 | -3.98 | YqgFc | smart domains | SM00732 | 2 | 2 | 9131 | 1249 |
SRBD1,SUPT6H |
| 1.870e-02 | -3.98 | RIO | smart domains | SM00090 | 2 | 2 | 9131 | 1249 |
RIOK1,RIOK3 |
| 1.870e-02 | -3.98 | CTD | smart domains | SM01104 | 2 | 2 | 9131 | 1249 |
SUPT5H,SRRM2 |
| 1.870e-02 | -3.98 | RNA Polymerase III Transcription Initiation From Type 2 Promoter | REACTOME pathways | R-HSA-76066 | 26 | 8 | 8202 | 1117 |
POLR3D,POLR3E,CRCP,POLR3B,GTF3C3,POLR1C,POLR3A,POLR3G |
| 1.870e-02 | -3.98 | RNA_SPLICING | MSigDB lists | RNA_SPLICING | 90 | 19 | 17758 | 2279 |
SCAF11,PRPF31,SFSWAP,TRA2A,SF3A3,NOL3,GEMIN5,SNW1,SRSF2,SYNCRIP,PHF5A,BCAS2,HNRNPH3,LUC7L3,NCBP2,ZRANB2,CELF1,SF3A1,SRPK2 |
| 1.875e-02 | -3.98 | aromatic compound catabolic process | biological process | GO:0019439 | 402 | 67 | 16441 | 2138 |
LIN28B,PAPD4,DCP1B,RPS29,PPP2R2A,NT5C3A,HMOX2,TNKS1BP1,PDE3A,PABPC4,EDC3,AMPD3,RPS16,ERI1,NT5C,ETF1,OGG1,SKIV2L,SKIV2L2,ITPA,UPP1,ALDH1L2,NUDT15,PDE8B,HPRT1,NOCT,MUTYH,SMG1,DROSHA,TATDN3,PDE4B,SMG7,ZFP36L1,MLH1,RNASEH2B,PARN,DCTPP1,PDE10A,UPF2,EXOSC4,ERI3,NT5M,CNOT4,PABPC1,NT5E,DIS3L2,EXOSC2,WDR61,PDE4A,EIF4A2,DHX34,RNH1,EXOG,PDE2A,PDE3B,CTIF,POP1,CAT,KPNA1,RPL28,ZCCHC6,ATM,CNOT6,NCBP2,TATDN1,PDE9A,AGO3 |
| 1.877e-02 | -3.98 | head development | biological process | GO:0060322 | 693 | 109 | 16441 | 2138 |
IMMP2L,ID1,PCNT,NF1,ATRX,PAFAH1B1,RBFOX2,C16orf45,MKS1,SIRT2,SEC16A,RAC3,AARS,KDM1A,RPGRIP1L,WNT2B,SKI,CHD7,ABL2,ZFHX3,UCHL5,ANKRD11,MYH3,ZNF148,RAN,CDK6,HTRA2,HSPA5,PSMG1,C5AR1,SATB2,EFHC1,TCTN1,FLVCR1,FGFR1,ARMC4,HPRT1,TCF7L1,BRCA2,G6PD,ARL13B,ATG7,H2AFX,SLC4A7,DLX2,NRP1,MAPT,FBXO45,BRAF,PAX2,MAPK8IP3,ID2,MAP1S,RTN4,ZIC2,TGFB2,GDPD5,TGFBR2,PHGDH,PITPNM1,CHD5,DDIT4,GART,UBE3A,SLC7A11,TSPAN2,CEP290,ATIC,ATXN2,NDRG4,DYNC2H1,IGF2BP1,ANP32B,ATP6V0D1,NT5E,KDM6B,FGF9,MSX1,TRNP1,IL11RA,FZD3,SETD2,ARID5B,LDHA,ATAT1,ARID1A,MEN1,PLCB1,FOXC1,NR2F1,TCF7L2,RERE,DKK1,NME7,HIF1A,HERC1,AGTPBP1,TBX3,CSRNP1,ZNF430,ATM,PEX13,RBPJ,APAF1,NCOR1,BMP4,NR2F2,NAPA,KAT6A |
| 1.878e-02 | -3.97 | BECKER_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | BECKER_TAMOXIFEN_RESISTANCE_DN | 49 | 12 | 17758 | 2279 |
MSX2,MSX1,BCAS2,SEMA3C,ME1,PEG10,NR2F2,CEP170,RBP1,FGFR1,PTPRK,OSBPL1A |
| 1.878e-02 | -3.97 | CAGTCAC,MIR-134 | MSigDB lists | CAGTCAC,MIR-134 | 49 | 12 | 17758 | 2279 |
APBB3,NRF1,SRSF2,UBAP2,KPNA3,EIF3J,SMARCAD1,BANF1,HIC2,ETF1,MBNL1,MAT2A |
| 1.879e-02 | -3.97 | AGGCACT,MIR-515-3P | MSigDB lists | AGGCACT,MIR-515-3P | 84 | 18 | 17758 | 2279 |
GATAD2B,FMNL3,SSFA2,BAZ2A,NPAS2,PAFAH1B1,ARHGEF12,RNF43,BCOR,PTPRG,SYT1,IKZF4,ZKSCAN1,DCTN4,LARP4B,STK4,GALE,KAT6A |
| 1.882e-02 | -3.97 | DCTN2 (dynactin 2 (p50)) | protein interactions | 10540 | 82 | 19 | 16036 | 2270 |
DCTN3,MCM6,PAFAH1B1,TPM4,PSMA1,MARCKSL1,CSPP1,NUP43,FLNB,UBC,POLR2A,DYNC1H1,BICD1,GADD45A,SMARCC1,DCTN4,SHMT2,RABEP1,SEH1L |
| 1.883e-02 | -3.97 | regulation of muscle tissue development | biological process | GO:1901861 | 101 | 21 | 16441 | 2138 |
EFNB2,BDNF,FGF9,NRAS,FGF2,NLN,SIRT2,TCF7L2,FGFR1,DKK1,SMAD3,GATA6,ARNTL,MKL2,RPS6KB1,RBPJ,BMP4,YBX3,UQCC2,HMGCR,MEF2C |
| 1.883e-02 | -3.97 | negative regulation of cellular amide metabolic process | biological process | GO:0034249 | 101 | 21 | 16441 | 2138 |
ATF4,AGO2,IGF2BP2,ENC1,GIGYF2,PAIP2,ABCA7,IGF2BP3,DDX3X,EPRS,EIF4ENIF1,IREB2,SYNCRIP,EIF2S1,CELF1,IGF2BP1,CLU,EIF2B3,SAMD4A,AGO3,TNRC6A |
| 1.883e-02 | -3.97 | regulation of muscle organ development | biological process | GO:0048634 | 101 | 21 | 16441 | 2138 |
EFNB2,BDNF,FGF9,NRAS,FGF2,NLN,SIRT2,TCF7L2,FGFR1,DKK1,SMAD3,GATA6,ARNTL,MKL2,RPS6KB1,RBPJ,BMP4,YBX3,UQCC2,HMGCR,MEF2C |
| 1.884e-02 | -3.97 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | MSigDB lists | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | 38 | 10 | 17758 | 2279 |
GTF2H3,ELL,SUPT4H1,CCNT1,CDK9,TCEB3,GTF2H1,NCBP2,SUPT5H,POLR2A |
| 1.884e-02 | -3.97 | chr14q21 | MSigDB lists | chr14q21 | 38 | 10 | 17758 | 2279 |
GNG2,RTN1,DDHD1,MGAT2,POLE2,HIF1A,EIF2S1,PNN,PRPF39,FKBP3 |
| 1.884e-02 | -3.97 | GU_PDEF_TARGETS_DN | MSigDB lists | GU_PDEF_TARGETS_DN | 38 | 10 | 17758 | 2279 |
EIF3C,PI4KB,KRT7,FOXO1,PIK3R4,ITGB4,TGFB2,FOXO3,FOXC1,PIK3CB |
| 1.884e-02 | -3.97 | ligand-dependent nuclear receptor binding | molecular function | GO:0016922 | 22 | 7 | 16491 | 2164 |
TADA3,SMARCD3,NCOR2,NCOR1,ARID1A,BAZ2A,SRA1 |
| 1.884e-02 | -3.97 | ferrous iron binding | molecular function | GO:0008198 | 22 | 7 | 16491 | 2164 |
ALKBH1,PLOD1,ALKBH3,FXN,UROD,NT5E,SNCA |
| 1.884e-02 | -3.97 | neuromuscular process controlling balance | biological process | GO:0050885 | 54 | 13 | 16441 | 2138 |
ABL2,PAFAH1B1,GRIN2C,RBFOX2,HERC1,KCNMA1,MYO7A,DLG4,BLOC1S4,RAC3,AARS,GIGYF2,PDE8B |
| 1.887e-02 | -3.97 | PRAF2 (PRA1 domain family, member 2) | protein interactions | 11230 | 12 | 5 | 16036 | 2270 |
RTN4,HMOX2,TSPAN5,ARL6IP5,PRAF2 |
| 1.887e-02 | -3.97 | SPRR2A (small proline-rich protein 2A) | protein interactions | 6700 | 12 | 5 | 16036 | 2270 |
DLG4,ABL1,PEX13,RNF2,EVPL |
| 1.887e-02 | -3.97 | ATG10 (autophagy related 10) | protein interactions | 83734 | 12 | 5 | 16036 | 2270 |
ATG12,USP7,USP11,ATG3,ATG7 |
| 1.887e-02 | -3.97 | TSPYL4 (TSPY-like 4) | protein interactions | 23270 | 12 | 5 | 16036 | 2270 |
NAP1L5,CELSR3,TFIP11,PNMA1,CCDC85B |
| 1.887e-02 | -3.97 | PIM2 (Pim-2 proto-oncogene, serine/threonine kinase) | protein interactions | 11040 | 12 | 5 | 16036 | 2270 |
ATXN1,SOCS1,ZNF821,CUTC,HNRNPH3 |
| 1.887e-02 | -3.97 | TTF1 (transcription termination factor, RNA polymerase I) | protein interactions | 7270 | 12 | 5 | 16036 | 2270 |
NIFK,PTRF,BAZ2A,SIRT7,SMAD7 |
| 1.887e-02 | -3.97 | FAM208A (family with sequence similarity 208, member A) | protein interactions | 23272 | 12 | 5 | 16036 | 2270 |
RNF2,CORO1A,ZCCHC7,BMI1,TOM1L1 |
| 1.887e-02 | -3.97 | KIF13A (kinesin family member 13A) | protein interactions | 63971 | 12 | 5 | 16036 | 2270 |
GTF2H1,ATF7IP,AP1B1,SMARCAD1,AP1M1 |
| 1.887e-02 | -3.97 | VGLL4 (vestigial-like family member 4) | protein interactions | 9686 | 12 | 5 | 16036 | 2270 |
TERF2IP,USP11,TEAD1,CDK6,MEF2C |
| 1.887e-02 | -3.97 | CCSER2 (coiled-coil serine rich protein 2) | protein interactions | 54462 | 12 | 5 | 16036 | 2270 |
GTF2H1,EXOC1,CRADD,STX1A,ATRX |
| 1.887e-02 | -3.97 | HIST1H2AL (histone cluster 1, H2al) | protein interactions | 8332 | 12 | 5 | 16036 | 2270 |
TERF2IP,CUL4A,GADD45A,COPS5,SAP30 |
| 1.887e-02 | -3.97 | TXNRD2 (thioredoxin reductase 2) | protein interactions | 10587 | 12 | 5 | 16036 | 2270 |
TADA3,GTF2H1,RDX,NCOR1,BCAS2 |
| 1.891e-02 | -3.97 | actomyosin | cellular component | GO:0042641 | 61 | 14 | 17570 | 2233 |
DBN1,PXN,NEBL,FSCN1,LIMA1,STX1A,TPM4,FERMT2,MYH9,ENAH,PTK2,TPM1,AMOT,FLNB |
| 1.891e-02 | -3.97 | Tonometry(PMID:17903302) | GWAS genes | Tonometry(PMID:17903302) | 10 | 5 | 2389 | 419 |
VPS37A,TGFBR2,EXOC4,MEF2C,PREX1 |
| 1.894e-02 | -3.97 | monocarboxylic acid catabolic process | biological process | GO:0072329 | 95 | 20 | 16441 | 2138 |
MCEE,XYLB,ACADS,SESN2,PCCA,CPT1A,ACOXL,MMAA,LPIN1,ECH1,ETFB,DECR1,PEX7,ETFDH,DCXR,ACOX1,LPIN2,BDH2,PEX13,CPT1C |
| 1.894e-02 | -3.97 | regulation of stem cell proliferation | biological process | GO:0072091 | 95 | 20 | 16441 | 2138 |
HMGA2,BDNF,FGF9,FBXW4,SIRT6,NF1,FZD3,SMARCD3,TGFBR2,KDM1A,FGFR1,IRS1,KCTD11,HIF1A,MYC,TBX3,ZEB1,BMP4,AGO3,N4BP2L2 |
| 1.896e-02 | -3.97 | Heme Biosynthesis | WikiPathways | WP561 | 9 | 4 | 4455 | 564 |
HMBS,ALAD,CPOX,UROD |
| 1.897e-02 | -3.96 | SAGA-type complex | cellular component | GO:0070461 | 33 | 9 | 17570 | 2233 |
TAF2,TADA3,WDR75,ATXN7,TRRAP,TAF4,SUPT20H,TAF12,TAF9B |
| 1.899e-02 | -3.96 | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 172 | 32 | 17758 | 2279 |
COBLL1,SPATS2,PHGDH,MAN1A1,SRPRB,SUB1,SLC7A11,SLC38A5,HIBCH,NOC3L,TRIP13,PERP,CEP128,NARS2,VOPP1,SEC24A,MCEE,GARS,GNG7,C11orf80,LIG4,EFHC1,CCDC113,SLC35F2,GALK2,CAV1,FKBP3,ACOXL,POLR3G,ALG5,CBWD1,RAB30 |
| 1.899e-02 | -3.96 | GSE29618_BCELL_VS_MONOCYTE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_UP | 172 | 32 | 17758 | 2279 |
ADAM19,IFT57,ST6GAL1,TCF3,SLC2A1,ZNF107,COBLL1,CHD7,SIPA1L3,MYC,SHMT2,NOC3L,PRKACB,NT5E,ZNF675,EVL,MPP6,DDX24,SLC38A1,ARID5B,GNG7,SLC35F2,ODC1,PWP1,PDLIM1,ATM,AEN,BBIP1,PPP3CC,SYNPO,RABEP1,RAB30 |
| 1.899e-02 | -3.96 | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | MSigDB lists | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | 172 | 32 | 17758 | 2279 |
SEPHS2,ARHGAP26,BTBD2,RHOBTB1,UBXN1,PID1,GAS6,AP1B1,FAM49A,ABL1,MCAM,KDM2A,NISCH,ZMYM2,LPCAT1,MAML3,SLC6A16,CAMKK2,EIF4A2,WDPCP,COL4A3BP,NLN,NEU1,LSS,KIAA0355,PSAP,RNF130,IQSEC2,ZNF397,XPO6,TESC,ZSWIM6 |
| 1.900e-02 | -3.96 | KRAS.DF.V1_UP | MSigDB lists | KRAS.DF.V1_UP | 185 | 34 | 17758 | 2279 |
MPI,SEC24D,PRSS3,DLGAP4,PID1,PTPRG,RPS6KA5,CUTC,BMP6,ETFB,RGS17,CTNNBL1,CBR4,MED24,CORO1A,TBC1D8,SAP30,ZNF654,AKAP12,SMARCD3,DKK1,CAT,RETSAT,PXDN,GATA6,G6PD,VCAN,CCDC85B,SLC4A7,NRP1,TSPAN5,SMYD3,TMEM158,STK4 |
| 1.900e-02 | -3.96 | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP | 185 | 34 | 17758 | 2279 |
ASCC1,PGPEP1,CUL4A,NDUFB5,VTI1A,SLC29A1,UBL5,TTLL11,NDUFV1,NBEA,ERRFI1,C15orf41,CAV2,FADS1,RAP1GAP2,MINA,METTL15,DCUN1D5,MEN1,SRA1,SAP30BP,VPS53,OXSR1,DDX3X,RETSAT,GRIK4,INTS5,COPS5,CUL2,SURF1,FKBP5,NDUFS5,RPS6KC1,HS2ST1 |
| 1.900e-02 | -3.96 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP | 185 | 34 | 17758 | 2279 |
LARS2,RBFOX2,PBX1,GAS6,PRKCA,FAM49A,ETFB,NUBPL,INTS7,UCHL5,ATIC,METTL8,ETF1,POLR3B,PRMT5,ZNF460,DSC3,MALL,ZCCHC14,APEX1,LAMC1,TUBA1A,RAP1GAP2,MINA,VIM,AGAP1,PDE3B,TCF7L2,STOML2,HLA-DMA,BAZ2B,CDKAL1,RNF130,EIF2B3 |
| 1.908e-02 | -3.96 | Vpr-mediated nuclear import of PICs | REACTOME pathways | R-HSA-180910 | 31 | 9 | 8202 | 1117 |
RANBP2,KPNA1,NUP133,BANF1,NUP43,NUP160,NUP214,POM121,SEH1L |
| 1.908e-02 | -3.96 | negative regulation of response to cytokine stimulus | biological process | GO:0060761 | 43 | 11 | 16441 | 2138 |
PTPN2,ZNF675,ECM1,PXDN,MAP2K5,PPARG,KLF4,DNAJA3,GAS6,CAV1,NOL3 |
| 1.908e-02 | -3.96 | sterol biosynthetic process | biological process | GO:0016126 | 43 | 11 | 16441 | 2138 |
LSS,IDI1,INSIG2,MVK,INSIG1,G6PD,FDPS,SQLE,DHCR7,FDFT1,HMGCR |
| 1.910e-02 | -3.96 | superpathway of cholesterol biosynthesis | BIOCYC pathways | HUMAN_PWY66-5 | 25 | 8 | 907 | 131 |
LSS,IDI1,MVK,FDPS,SQLE,DHCR7,HMGCR,FDFT1 |
| 1.911e-02 | -3.96 | HTH_MYB | prosite domains | PS51294 | 9 | 4 | 11866 | 1504 |
DMTF1,SNAPC4,TERF2,MYB |
| 1.911e-02 | -3.96 | BEACH | prosite domains | PS50197 | 9 | 4 | 11866 | 1504 |
NBEA,NBEAL1,WDFY3,LYST |
| 1.913e-02 | -3.96 | negative regulation of cell cycle | biological process | GO:0045786 | 464 | 76 | 16441 | 2138 |
SART1,CHMP2A,THOC5,CUL4A,KMT2E,PRKAB2,CSNK2A1,SMARCA4,NLE1,TOM1L1,DST,ANAPC1,ZFHX3,ANAPC11,ANAPC10,MAD1L1,CDK6,HTRA2,PRKACB,PRPF19,PTPRK,ZBTB17,BRD4,CDK4,BRCA1,SOX4,SMAD3,SKIL,CDC16,TRRAP,TOM1L2,CHMP4C,HMGA2,XPC,KHDRBS1,LAMTOR3,GAS6,TGFB2,PSMF1,CDC73,GIGYF2,MAD2L2,ABL1,MYC,TRIAP1,FBXO31,DMRT1,TERF2,PPP1R9B,CRADD,FOXN3,FZD3,TEX14,PSMA1,TBRG4,TPRA1,MEN1,TRIM37,FOXC1,TCF7L2,UBE2E1,ZNF655,UBC,MFN2,KLHL22,GADD45A,CDK9,CUL2,RRAGA,ATM,BMP4,NR2F2,ZAK,ANAPC4,SGSM3,DDIT3 |
| 1.924e-02 | -3.95 | PILON_KLF1_TARGETS_UP | MSigDB lists | PILON_KLF1_TARGETS_UP | 484 | 78 | 17758 | 2279 |
CGN,PIGM,AMOTL1,CYLD,PAPD4,OLA1,PBX1,SPATS2L,PLEK2,SLC6A8,IGSF1,CIAPIN1,ESAM,ZSWIM7,LPIN2,ME1,HIBCH,SERPINH1,COL5A2,MIOS,HARS,DHX57,S100A16,DCBLD2,CXADR,OSBPL1A,SNCA,ZNF266,GATA6,RAD18,CCNT1,HIPK2,FTSJ1,ABCC3,CLU,TMEM158,RBP1,LPP,DNAJA4,PIGN,FN1,TRIO,PCSK7,WDR37,DNAJC22,CSNK1A1,GIGYF2,MBNL1,FOXO3,ZNF239,ASAP1,HARS2,MFAP2,LARP4B,AMOT,N4BP2,CLK2,VOPP1,TMC7,HBG2,TTLL5,WDR61,GINS3,TEAD1,PCCA,TBXAS1,WWC1,FERMT2,EXOG,SLC23A2,EXOC6,VPS13C,RARS,MTHFD2,KPNA1,PXDN,KIAA0355,PRKAR2A |
| 1.926e-02 | -3.95 | damaged DNA binding | molecular function | GO:0003684 | 65 | 15 | 16491 | 2164 |
GTF2H3,POLB,RBBP8,RAD18,APEX1,TP53BP1,XPC,POLK,MSH3,H2AFX,MSH4,BRCA1,APTX,OGG1,RPA1 |
| 1.927e-02 | -3.95 | YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta) | protein interactions | 10971 | 427 | 76 | 16036 | 2270 |
MYCBP2,CUL7,ACTG1,AARS2,MYH9,CSNK2A1,ANKRD18A,HSPA1A,PDE3A,PABPC4,EDC3,ZC3H13,COPS4,PPFIBP1,MRPS27,RMDN3,SSBP1,VCL,LYST,ZBTB17,PHLDB2,PDK1,TUBA1A,SSFA2,LIMA1,VIM,MEF2D,DENND4A,CHAF1A,SNCA,EXO1,DDX3X,G6PD,H2AFX,FUS,ANXA2,TPM1,NOLC1,CEP170,MAPT,TTN,BRAF,FOXO1,FN1,LARS2,KLC4,KIF5C,VARS,AKT1S1,CSNK1A1,FOXO3,SPIRE1,ABL1,SIPA1L3,PI4KB,MYC,PRMT5,NRIP1,RPS6KB2,SIK3,WDR61,USP42,LDHA,WWC1,PDE3B,PIK3CB,PGD,ANXA1,DYNC1H1,TPD52L2,NME7,FSCN1,CUL2,ITGB4,RABEP1,ARHGAP10 |
| 1.931e-02 | -3.95 | Seh1-associated complex | cellular component | GO:0035859 | 9 | 4 | 17570 | 2233 |
NPRL2,MIOS,SEH1L,RRAGA |
| 1.931e-02 | -3.95 | cytoplasmic mRNA processing body assembly | biological process | GO:0033962 | 13 | 5 | 16441 | 2138 |
DYNC1H1,NOCT,LSM14A,ATXN2,EDC3 |
| 1.931e-02 | -3.95 | negative regulation of fatty acid biosynthetic process | biological process | GO:0045717 | 13 | 5 | 16441 | 2138 |
TRIB3,INSIG2,BRCA1,INSIG1,PIBF1 |
| 1.931e-02 | -3.95 | regulation of necroptotic process | biological process | GO:0060544 | 13 | 5 | 16441 | 2138 |
RIPK1,RBCK1,CAV1,YBX3,BIRC2 |
| 1.931e-02 | -3.95 | cellular response to arsenic-containing substance | biological process | GO:0071243 | 13 | 5 | 16441 | 2138 |
DDX3X,HMBS,ATF4,GSTO2,UROD |
| 1.931e-02 | -3.95 | CDP-diacylglycerol biosynthetic process | biological process | GO:0016024 | 13 | 5 | 16441 | 2138 |
TAMM41,GPAM,LCLAT1,AGPAT4,GPAT3 |
| 1.931e-02 | -3.95 | negative regulation of necrotic cell death | biological process | GO:0060547 | 13 | 5 | 16441 | 2138 |
RBCK1,CAV1,YBX3,NOL3,BIRC2 |
| 1.931e-02 | -3.95 | negative regulation of neurotransmitter transport | biological process | GO:0051589 | 13 | 5 | 16441 | 2138 |
BRAF,RAP1A,NF1,RAP1B,SNCA |
| 1.931e-02 | -3.95 | negative regulation of peptidyl-threonine phosphorylation | biological process | GO:0010801 | 13 | 5 | 16441 | 2138 |
SPRED2,SIRT2,PARD3,DDIT4,SMAD7 |
| 1.931e-02 | -3.95 | interleukin-1-mediated signaling pathway | biological process | GO:0070498 | 13 | 5 | 16441 | 2138 |
EGR1,RPS6KA5,PLCB1,IRAK2,IKBKB |
| 1.932e-02 | -3.95 | RNF111 (ring finger protein 111) | protein interactions | 54778 | 50 | 13 | 16036 | 2270 |
SMAD3,SKIL,XPC,RB1CC1,ANAPC11,SMAD7,SUMO3,CSNK2A1,RNF111,UBE2K,LRSAM1,UBE2E1,SKI |
| 1.932e-02 | -3.95 | ANAPC7 (anaphase promoting complex subunit 7) | protein interactions | 51434 | 50 | 13 | 16036 | 2270 |
ANAPC1,CDC16,ANAPC13,TP53BP1,SUPT6H,SIRT6,PRKCSH,COPS5,SMARCAD1,TAF4,ANAPC10,ANAPC4,UBC |
| 1.932e-02 | -3.95 | STK11 (serine/threonine kinase 11) | protein interactions | 6794 | 50 | 13 | 16036 | 2270 |
SMARCC1,COPS4,COPS3,H2AFX,ATM,SMARCA4,RPS6KB1,FKBP5,USP11,RPS6KA5,HSPA1A,PARD3,CDC37 |
| 1.932e-02 | -3.95 | PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 54623 | 50 | 13 | 16036 | 2270 |
KAT8,RNF40,WDR61,CDK9,CTR9,CSNK2A1,CHD2,SUPT5H,KMT2A,CDC73,UBE2E1,POLR2A,CHAF1A |
| 1.932e-02 | -3.95 | ANP32B (acidic nuclear phosphoprotein 32 family member B) | protein interactions | 10541 | 50 | 13 | 16036 | 2270 |
KPNA1,FN1,UCHL5,VPS72,POLR1A,ACTR3,CSNK2A1,AHCYL1,BAG1,AHCYL2,CHAF1A,SH3GL1,RPA1 |
| 1.932e-02 | -3.95 | DYRK2 (dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2) | protein interactions | 8445 | 50 | 13 | 16036 | 2270 |
TTN,RB1CC1,HSPA5,PCMT1,ATM,SSBP2,DLST,UBR5,DCAF5,HSPA1A,HSPA1B,RAD54B,RPA1 |
| 1.937e-02 | -3.94 | KIAA0368 (KIAA0368) | protein interactions | 23392 | 116 | 25 | 16036 | 2270 |
TIMM8B,SNU13,CCDC57,RAB11FIP4,TUBA1A,FN1,ANKRD17,MYO10,ANK2,SIRT7,WDR26,UBR4,HSPA1A,ZNF483,DST,FARSA,TSR1,KDM2A,UCHL5,TATDN1,RABEP1,KIF1B,HNRNPM,BAG1,SPTAN1 |
| 1.937e-02 | -3.94 | NCOA3 (nuclear receptor coactivator 3) | protein interactions | 8202 | 116 | 25 | 16036 | 2270 |
NCOR2,PPARG,NPAS2,RFX1,MYH9,BRCA1,BMP6,NR2F1,SPOP,SMAD3,ABL1,VDR,UBE3A,BRE,SUFU,TP53BP1,MYC,IKBKB,MKL2,ANKRD11,NCOR1,ANXA2,ETV1,CARM1,MORC2 |
| 1.941e-02 | -3.94 | Annexin | pfam domains | PF00191 | 13 | 5 | 16629 | 2165 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 1.944e-02 | -3.94 | CTTN (cortactin) | protein interactions | 2017 | 99 | 22 | 16036 | 2270 |
TNK2,ARHGAP17,SARS,GARS,PXN,ACTG1,VTA1,ACTR3,PTK2,RPA1,ARPC3,ACD,ASAP1,CHD3,ATG7,SUCLG2,SHMT2,RDX,ME1,MET,SH3PXD2A,CDC37 |
| 1.945e-02 | -3.94 | CELLULAR_BIOSYNTHETIC_PROCESS | MSigDB lists | CELLULAR_BIOSYNTHETIC_PROCESS | 312 | 53 | 17758 | 2279 |
CHST11,EIF3C,DPH1,MRPL10,GPR143,FARS2,PLOD1,IGF2BP2,TGFB2,COX10,AARS,BMP6,PABPC4,PAIP2,PEX7,ETF1,ME1,PTGS1,CMPK1,ALDH18A1,PNPLA3,GMDS,YARS,COQ3,SAMD4A,CSGALNACT2,RPS6KB2,FADS1,ATF4,KRT7,TSTA3,PPAT,MTIF2,EIF3J,CPOX,EIF4A2,BRCA1,EIF2A,ABCF1,EIF3H,HSD3B7,PYCR1,WARS,RARS,DDAH2,HPRT1,RPL28,ALAD,COPS5,UMPS,EIF2B3,ADK,PDSS2 |
| 1.956e-02 | -3.93 | MSL1 (male-specific lethal 1 homolog (Drosophila)) | protein interactions | 339287 | 30 | 9 | 16036 | 2270 |
PAF1,KAT8,RNF40,SNW1,SMARCC1,TP53BP1,CDK9,RAN,AHCYL2 |
| 1.956e-02 | -3.93 | ANAPC11 (anaphase promoting complex subunit 11) | protein interactions | 51529 | 30 | 9 | 16036 | 2270 |
CDC16,BIRC6,ANAPC11,ANAPC10,NKD2,RNF111,UBE2K,UBC,ANAPC4 |
| 1.956e-02 | -3.93 | NEURL4 (neuralized E3 ubiquitin protein ligase 4) | protein interactions | 84461 | 30 | 9 | 16036 | 2270 |
HERC2,UBE3A,CEP290,USP20,MAP7D1,CEP170,VAC14,POLR2A,RPA1 |
| 1.956e-02 | -3.93 | PPHLN1 (periphilin 1) | protein interactions | 51535 | 30 | 9 | 16036 | 2270 |
CCDC57,PPHLN1,SHMT2,VIM,BRCA1,BMI1,CDK6,CDC37,CLK2 |
| 1.956e-02 | -3.93 | TOM1 (target of myb1 membrane trafficking protein) | protein interactions | 10043 | 30 | 9 | 16036 | 2270 |
GARS,PTBP2,ZNF512B,ME1,EXOSC4,SSBP2,EEA1,NEDD4,UBC |
| 1.956e-02 | -3.93 | PABPN1 (poly(A) binding protein, nuclear 1) | protein interactions | 8106 | 30 | 9 | 16036 | 2270 |
SNW1,COPS5,CUL2,SMARCA4,BMI1,PRMT3,CARM1,ARIH2,UBC |
| 1.956e-02 | -3.93 | PLOD1 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1) | protein interactions | 5351 | 30 | 9 | 16036 | 2270 |
GEMIN5,COPS5,SIRT7,CUL2,H2AFX,PLOD1,NCDN,ISG15,TERF2 |
| 1.956e-02 | -3.93 | BIRC7 (baculoviral IAP repeat containing 7) | protein interactions | 79444 | 30 | 9 | 16036 | 2270 |
PCNT,WIZ,NFKBIB,POLR1C,UBE2K,BIRC2,UBE2E1,HTRA2,UBC |
| 1.956e-02 | -3.93 | CPSF3 (cleavage and polyadenylation specific factor 3) | protein interactions | 51692 | 30 | 9 | 16036 | 2270 |
SMARCAD1,SIRT7,RRAGA,FIP1L1,WDR33,SYMPK,CDC73,POLR1E,POLR2A |
| 1.956e-02 | -3.93 | TEAD4 (TEA domain family member 4) | protein interactions | 7004 | 30 | 9 | 16036 | 2270 |
AMOTL1,FN1,TEAD1,VTA1,CCDC85B,VPS52,CCNDBP1,PARN,PNMA1 |
| 1.956e-02 | -3.93 | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 632 | 99 | 17758 | 2279 |
KCTD7,PRKCSH,TNFRSF21,MFGE8,SLC2A1,CERS5,TMEM109,CD99L2,SLC29A1,ZMAT2,LCLAT1,FLNB,SLC30A7,SRPRB,SREBF2,SOCS1,ATP5G2,PPFIBP1,SLC39A7,SLC38A2,ANKRD11,CLCN6,ZNF142,SERPINH1,TSPAN14,VCL,PTPRK,TLCD1,FLNC,ZCCHC14,SLC38A1,ATG9A,SFSWAP,HSPA5,ATP6V0A1,SHISA5,ENC1,SON,SLC50A1,SLC9A5,FGFR1,DCBLD2,SLC39A14,ZNF266,DNAJC1,CCNT1,SYNGR2,LARGE,SLC4A7,SCARB1,TMEM101,PDCD11,TMEM158,METTL2B,TMEM33,HMGA2,SCAMP3,ITPRIP,B4GALT5,DPF2,TRIO,RTN4,WDR26,VARS,DNAJC22,MFHAS1,MFSD10,PI4KB,TMEM161A,NISCH,PPIL2,STC2,KDELC1,CTR9,PTGS1,HSD17B12,HMGCR,SIGMAR1,RAP1GAP2,TYW1,PEAR1,ARID1A,YIPF3,LENG8,MEN1,POLR3A,SLC23A2,CTIF,MGAT2,RETSAT,PXDN,SERINC1,ZZEF1,SRD5A3,GLG1,SLC16A1,SQLE,IPO4,HS2ST1 |
| 1.956e-02 | -3.93 | GGGYGTGNY_UNKNOWN | MSigDB lists | GGGYGTGNY_UNKNOWN | 632 | 99 | 17758 | 2279 |
DLL4,TRERF1,OLFM2,KIF5A,ZBTB37,SLC25A21,LTB4R,DHX35,SEMA6A,FLNB,IGSF1,SMARCB1,RTN1,JAG1,PDZD2,CAMTA2,ATP5G2,SLC38A2,RNF111,ZEB1,CHD2,ADCK4,CDK6,PERP,MALL,TUBA1A,ZNF414,HSPA5,LGALS1,NLN,VIM,CAV1,MEF2D,KCNH2,UBR4,RAB10,ZFAND3,SLC7A1,TCF7L1,DDAH2,AHNAK,IKZF4,HNRNPR,SH3RF1,PER1,EEFSEC,ARL4A,CBWD1,SRFBP1,ANXA2,SPOCK2,RAB30,USP15,NOSTRIN,JUP,C17orf80,FAM46B,HSD17B10,SLC25A12,XPO7,BHLHE40,RPS6KA5,CHD5,GIGYF2,BMP6,DDIT4,FKBP1A,ATXN7L1,ELL,NOVA2,RAPGEFL1,CELF1,CD44,AMOT,SIK3,BDNF,PXN,LSM12,ZMYM5,BCS1L,WDR25,ATAT1,PACS1,LENG8,CPT1A,MFN2,POLR3G,RDH11,EXOC6,GPC2,FGFBP1,STX1A,CSRNP1,SENP3,ITGB4,NAPA,PDLIM5,SLC16A10,SLC43A1 |
| 1.956e-02 | -3.93 | human chr1q21 | chromosome location | human chr1q21 | 78 | 14 | 26250 | 2590 |
CGN,ECM1,SCAMP3,SHC1,PI4KB,S100A10,FAM189B,VPS72,MCL1,IL6R,HIST2H2AB,S100A16,SLC39A1,CLK2 |
| 1.958e-02 | -3.93 | - | gene3d domains | 1.10.3500.10 | 2 | 2 | 9988 | 1398 |
SRBD1,SUPT6H |
| 1.958e-02 | -3.93 | - | gene3d domains | 3.40.50.10050 | 2 | 2 | 9988 | 1398 |
EIF5B,MTIF2 |
| 1.958e-02 | -3.93 | - | gene3d domains | 3.30.420.110 | 2 | 2 | 9988 | 1398 |
MSH4,MSH3 |
| 1.958e-02 | -3.93 | - | gene3d domains | 3.40.980.10 | 2 | 2 | 9988 | 1398 |
FLAD1,GPHN |
| 1.958e-02 | -3.93 | - | gene3d domains | 3.30.420.140 | 2 | 2 | 9988 | 1398 |
SRBD1,SUPT6H |
| 1.958e-02 | -3.93 | - | gene3d domains | 3.30.1360.70 | 2 | 2 | 9988 | 1398 |
RARS,RARS2 |
| 1.959e-02 | -3.93 | PRTYPHPHTASE | prints domains | PR00700 | 36 | 8 | 4759 | 462 |
PTPN2,PTPRM,PTPRA,PTPN12,PTPN4,PTPRG,PTPN14,PTPRK |
| 1.968e-02 | -3.93 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 35 | 17758 | 2279 |
SERINC5,JUP,URB2,ISG20L2,SLC6A8,AARS,MGA,NRF1,MPHOSPH10,ASNS,GATC,VPS52,ZNF148,MAP3K14,ITGAX,TOMM34,PABPC1,TRIP13,MICAL3,ATF4,GARS,TSTA3,FOXN3,HSPA5,GPNMB,STK10,MAK16,TARS,TPD52L2,AHNAK,CUL2,SGSM2,SVIL,KDM4C,DDIT3 |
| 1.968e-02 | -3.93 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | 192 | 35 | 17758 | 2279 |
WDR74,FAM189B,TUBB6,SLC25A44,MAN1A1,IDI1,PMAIP1,KDELC1,PPCDC,PAK1IP1,TIMELESS,JOSD1,YARS,PRF1,HTRA2,SAP30,MTHFD1,DBN1,WARS2,AP4S1,DDX41,CDK4,ELOVL6,IDH3G,LGALS1,BRCA1,UBE2K,PYCR1,RAD54B,YIF1A,ASCC3,MTHFD2,POLE2,SLC25A11,TMEM33 |
| 1.968e-02 | -3.93 | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | 192 | 35 | 17758 | 2279 |
SLC12A7,CARS,ADAM19,JUP,ATP6V1A,PTPRA,PBX1,TUBB6,REEP5,HDDC2,PHC2,TTC1,RNF141,FKBP1A,NEK6,UCHL5,GTF2H1,SELT,ETF1,SLC25A1,ANAPC13,IL11RA,KRTCAP2,ODC1,C19orf70,MAT2A,ARPC3,SPOP,GNG2,ARID3B,RIOK3,NCBP2,MDN1,RPS6KC1,ADK |
| 1.968e-02 | -3.93 | GSE17721_PAM3CSK4_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_2H_BMDM_UP | 192 | 35 | 17758 | 2279 |
TTN,APRT,SLC25A44,IL17RE,ZNF239,SHC1,CEP290,SNTG2,UTS2,CD44,PRMT5,CALN1,NIPSNAP1,FAM127A,ZNF124,ZNF821,KDM5A,NOL6,NXN,IL6R,METTL22,MMAA,SNCA,HTR7,FBXO21,APBB3,SRCAP,SMARCC1,IKZF4,ARL4A,POLR3E,CRCP,PUS1,DCAF5,RFXAP |
| 1.968e-02 | -3.93 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | 192 | 35 | 17758 | 2279 |
PPDPF,XPC,DYM,ST6GAL1,PIP4K2A,MLX,FBL,PRMT3,CDC37,DEAF1,HBG2,TSTA3,ITPA,YIPF3,CCNDBP1,IMPDH2,C8orf33,UBR4,MAT2A,RERE,TIMM44,PWP1,SRCAP,DDX50,SRP68,NSMCE1,ORC5,INTS9,EIF2S1,GALNT10,PSAP,CNDP2,SETD6,IPO4,MTCH1 |
| 1.968e-02 | -3.93 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | 192 | 35 | 17758 | 2279 |
PPDPF,FAM189B,HSD17B10,SLC9B2,HMOX2,CMTM3,PIP4K2A,FAM50A,S100A10,MCM5,BUD31,METTL8,ANXA5,PRKACB,SERBP1,HNRNPM,CTC1,MYB,GLTSCR2,TMEM126A,FERMT2,MCM2,FOXC1,ARPC3,RPA1,CCDC28B,HLA-DMA,PDLIM1,NSMCE1,HNRNPH3,PQBP1,INTS9,NRP1,SYNPO,MTCH1 |
| 1.971e-02 | -3.93 | FA58C_1 | prosite domains | PS01285 | 18 | 6 | 11866 | 1504 |
NRP1,CNTNAP3,CNTNAP3B,MFGE8,DCBLD2,DDR2 |
| 1.975e-02 | -3.92 | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | 179 | 33 | 17758 | 2279 |
SLC12A7,KCTD7,ARHGAP26,PDK4,SLC25A12,ID2,FARS2,SSBP2,TGFB2,GDPD5,DENND3,MFSD10,IGSF1,SLC25A20,NUP133,ZDHHC6,ZFP37,PCOLCE2,CCDC88C,TRMT12,NT5E,PSAT1,ZNF480,ARID5B,TYW1,CAMSAP2,SLC35D1,PES1,RARS,WDR7,ALKBH1,TNFRSF10D,ADK |
| 1.975e-02 | -3.92 | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP | 179 | 33 | 17758 | 2279 |
TCF12,CELSR1,MED13L,HES6,ST3GAL6,GIGYF2,SACS,ECM1,NISCH,PRICKLE2,B3GNTL1,CASP8AP2,TERF2,ANTXR2,FAM127A,KDM5B,AP4S1,PTPN12,ZNF467,TRAPPC6B,TPRA1,RAB10,ZNF708,MSRA,IREB2,STX1A,CCDC146,RPS6KB1,DLX2,IGBP1,ZBTB11,XRCC4,TESC |
| 1.977e-02 | -3.92 | MODULE_256 | MSigDB lists | MODULE_256 | 55 | 13 | 17758 | 2279 |
SARS,MIF4GD,LRRC40,ZNF160,PAK1IP1,FNTB,ST7L,RSF1,NUP214,CHCHD6,ZC3H3,YTHDF2,ABCA7 |
| 1.977e-02 | -3.92 | BEACH_dom | interpro domains | IPR000409 | 9 | 4 | 18293 | 2341 |
NBEA,NBEAL1,WDFY3,LYST |
| 1.977e-02 | -3.92 | rSAM | interpro domains | IPR007197 | 9 | 4 | 18293 | 2341 |
CDKAL1,LIAS,ELP3,TYW1 |
| 1.977e-02 | -3.92 | Myb_dom | interpro domains | IPR017930 | 9 | 4 | 18293 | 2341 |
DMTF1,SNAPC4,TERF2,MYB |
| 1.977e-02 | -3.92 | GTPase-bd | interpro domains | IPR010473 | 9 | 4 | 18293 | 2341 |
INF2,FMNL3,FMNL1,FMNL2 |
| 1.977e-02 | -3.92 | MCM_dom | interpro domains | IPR001208 | 9 | 4 | 18293 | 2341 |
MCM6,MCM2,MCM9,MCM5 |
| 1.977e-02 | -3.92 | Methyltransf_11 | interpro domains | IPR013216 | 9 | 4 | 18293 | 2341 |
NDUFAF5,ALKBH8,CIAPIN1,WBSCR22 |
| 1.977e-02 | -3.92 | RAWUL | interpro domains | IPR032443 | 9 | 4 | 18293 | 2341 |
PCGF3,RNF2,BMI1,RING1 |
| 1.977e-02 | -3.92 | S1_domain | interpro domains | IPR003029 | 9 | 4 | 18293 | 2341 |
EIF2S1,SRBD1,SUPT6H,PDCD11 |
| 1.977e-02 | -3.92 | FH3_dom | interpro domains | IPR010472 | 9 | 4 | 18293 | 2341 |
INF2,FMNL3,FMNL1,FMNL2 |
| 1.982e-02 | -3.92 | regulation of protein modification by small protein conjugation or removal | biological process | GO:1903320 | 275 | 48 | 16441 | 2138 |
EGR1,UBXN1,SMAD7,RCHY1,BIRC2,PSMF1,UBR5,HSPA1A,MAD2L2,KDM1A,RNF40,ABL1,FKBP1A,ANAPC1,UBE3A,ANAPC11,ANAPC10,MAD1L1,RNF111,CTR9,PRMT3,ARRDC3,HSPA5,TEX14,NXN,SUMO3,PSMA1,BRCA1,CAV1,DCUN1D5,PTK2,SOX4,ARRDC4,HERPUD1,UBC,UBE2E1,ISG15,HSPA1B,TRIB3,KLHL22,CDC16,CDK9,DNAJA3,ATG7,ATM,CLU,BMI1,ANAPC4 |
| 1.983e-02 | -3.92 | RPAP1 (RNA polymerase II associated protein 1) | protein interactions | 26015 | 45 | 12 | 16036 | 2270 |
TERF2IP,ANAPC1,SNU13,MCM10,LAGE3,GPN1,HLTF,IGF2BP1,POLR3B,IGBP1,PPIL3,POLR3A |
| 1.983e-02 | -3.92 | SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3) | protein interactions | 6604 | 45 | 12 | 16036 | 2270 |
DPF3,SMARCC1,PPARG,DPF2,PBX1,SMARCA4,ARHGAP1,UPF2,TBL1X,ARID1A,ARID1B,SMARCB1 |
| 1.983e-02 | -3.92 | ZC3H13 (zinc finger CCCH-type containing 13) | protein interactions | 23091 | 45 | 12 | 16036 | 2270 |
CDK9,MED27,SIRT7,MED15,MED24,CSNK2A1,MED16,MED20,BMI1,POLR2A,TERF2,USP15 |
| 1.984e-02 | -3.92 | chromatin remodeling | biological process | GO:0006338 | 164 | 31 | 16441 | 2138 |
HMGA2,GATAD2B,BRD4,BAZ2A,ATRX,SUPT6H,SMARCAD1,SMARCA4,SCMH1,SMARCD3,SATB2,RSF1,ARID1A,HIST1H4J,SUPT5H,CHD5,ARID1B,RERE,CENPP,SMARCB1,TOX4,BAZ1A,UBTF,SUPT4H1,SMARCC1,SUV39H2,MBD2,MYC,VPS72,MYB,TOP1 |
| 1.986e-02 | -3.92 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 436 | 71 | 17758 | 2279 |
DNM3,ID1,RBFOX2,ENAH,LPCAT3,TUBB6,SLC25A44,SLC6A8,CSTA,FLNB,JAG1,MET,PEG10,SPAG6,HN1,DBN1,ZCCHC14,GPM6A,TUBA1A,TFPI,ATF7IP2,ATG12,AKAP12,MARCKSL1,EFHC1,AKAP13,COTL1,SOX4,ODC1,FGFR1,DDAH2,BRCA2,G6PD,ZNF557,WDR7,AHNAK2,DLX2,TPM1,ZMAT3,MAPT,MEF2C,KLHL24,EFNB2,FN1,JUP,TRIP6,EGR1,KIF5C,ID2,PHLDA2,FAM49A,TADA3,DOPEY1,RNFT2,DMRT1,ATP6V0D1,ADARB1,MSX1,KDM5B,NXN,SMARCD3,SNAP25,PTK2,SYT1,NEU1,SPAG9,FSCN1,SNAP23,ORC5,PSAP,PDLIM5 |
| 1.987e-02 | -3.92 | NS-carcinoid-endocrine_tumour | COSMIC cancer mutations | NS-carcinoid-endocrine_tumour | 9 | 4 | 17775 | 2278 |
BRAF,NRAS,MET,MEN1 |
| 1.987e-02 | -3.92 | ovary-carcinoma-Brenner_tumour | COSMIC cancer mutations | ovary-carcinoma-Brenner_tumour | 9 | 4 | 17775 | 2278 |
BRAF,BRCA1,CYLD,MAP2K4 |
| 1.987e-02 | -3.92 | central_nervous_system-medulla-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-medulla-glioma-astrocytoma_Grade_I | 9 | 4 | 17775 | 2278 |
BRAF,NRAS,NF1,KIAA1549 |
| 1.987e-02 | -3.92 | soft_tissue-other-neoplasm | COSMIC cancer mutations | soft_tissue-other-neoplasm | 9 | 4 | 17775 | 2278 |
FUS,BRAF,NRAS,NF1 |
| 1.988e-02 | -3.92 | HSP90B1 (heat shock protein 90kDa beta (Grp94), member 1) | protein interactions | 7184 | 122 | 26 | 16036 | 2270 |
CUL7,CUL4A,PRKCSH,RAB7A,HSPA5,METTL23,SMARCA4,CSNK2A1,MARS,BIRC2,TSR1,SMARCC1,KPNA3,KDM4B,ZBTB8OS,FMNL1,COPS5,CUL2,H2AFX,SUCLG2,FUS,CLU,COPS6,TPM1,HSD17B12,TERF2 |
| 1.995e-02 | -3.91 | PCBP1 (poly(rC) binding protein 1) | protein interactions | 5093 | 157 | 32 | 16036 | 2270 |
MPI,CUL7,FN1,TRIP6,TCF3,TUBB6,HNRNPLL,ANXA7,MYC,TRIAP1,MET,PABPC1,TERF2,RPS6KB2,SRPK2,CDC37,PSAT1,LSM12,SMARCAD1,LGALS1,COTL1,PITPNB,CPT1A,PIK3CB,FSCN1,COPS5,CUL2,ACP1,IGBP1,ADK,FAHD1,PPIL3 |
| 1.995e-02 | -3.91 | cell cortex | cellular component | GO:0005938 | 234 | 41 | 17570 | 2233 |
PAFAH1B1,STXBP6,SLC2A1,MYO7A,MYH9,ARFIP2,PPP1R9A,FLNB,NEDD4,SPIRE1,DST,EXOC1,FMNL1,RDX,CORO1A,VCL,SPTAN1,DBN1,PHLDB2,PXN,MYO10,EXOC6B,WDPCP,TPM4,DLG4,FERMT2,AKAP12,ARHGAP32,CAV1,PTK2,RAB10,BSN,SNCA,EXOC6,MISP,EXOC4,ANXA2,SEPT5,FNBP1L,C2CD5,PARD3 |
| 1.995e-02 | -3.91 | salivary_gland-submandibular-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-submandibular-carcinoma-adenoid_cystic_carcinoma | 33 | 9 | 17775 | 2278 |
UBTF,SYCP2L,LRP1B,BRAF,NRAS,PRDM16,SPEN,CHD2,ZNF507 |
| 1.996e-02 | -3.91 | negative regulation of protein catabolic process | biological process | GO:0042177 | 120 | 24 | 16441 | 2138 |
BANP,MYCBP2,UBXN1,OPHN1,TEX14,CSNK2A1,SIRT2,PSMF1,MAD2L2,UBE2E1,SMAD3,ANAPC1,KLHL22,CDC16,SMARCC1,GRIN2C,WAC,ANAPC11,ANAPC10,MAD1L1,ATM,FHIT,ANXA2,ANAPC4 |
| 1.997e-02 | -3.91 | PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS | 9 | 4 | 17758 | 2279 |
UMPS,NT5C,CMPK1,NT5M |
| 1.997e-02 | -3.91 | chr3p13 | MSigDB lists | chr3p13 | 9 | 4 | 17758 | 2279 |
ZBED2,CD96,SHQ1,MGLL |
| 1.998e-02 | -3.91 | exocyst | cellular component | GO:0000145 | 18 | 6 | 17570 | 2233 |
EXOC1,STXBP6,EXOC6B,RAB10,EXOC6,EXOC4 |
| 2.003e-02 | -3.91 | BPY2C (basic charge, Y-linked, 2C) | protein interactions | 442868 | 2 | 2 | 16036 | 2270 |
MAP1S,UBE3A |
| 2.003e-02 | -3.91 | RABGEF1 (RAB guanine nucleotide exchange factor (GEF) 1) | protein interactions | 282335 | 2 | 2 | 16036 | 2270 |
RABEP1,UBC |
| 2.003e-02 | -3.91 | uspl1 (ubiquitin specific peptidase like 1) | protein interactions | 445403 | 2 | 2 | 16036 | 2270 |
SUMO3,RANGAP1 |
| 2.003e-02 | -3.91 | SGMS1 (sphingomyelin synthase 1) | protein interactions | 259230 | 2 | 2 | 16036 | 2270 |
ATXN1,STK4 |
| 2.003e-02 | -3.91 | RPL39L (ribosomal protein L39-like) | protein interactions | 116832 | 2 | 2 | 16036 | 2270 |
CCNDBP1,SRPK2 |
| 2.003e-02 | -3.91 | NEURL3 (neuralized E3 ubiquitin protein ligase 3) | protein interactions | 93082 | 2 | 2 | 16036 | 2270 |
CCNDBP1,UBC |
| 2.003e-02 | -3.91 | Atg10 (autophagy related 10) | protein interactions | 66795 | 2 | 2 | 16036 | 2270 |
ATG12,ATG7 |
| 2.003e-02 | -3.91 | MIR4435-2HG (MIR4435-2 host gene) | protein interactions | 541471 | 2 | 2 | 16036 | 2270 |
BANP,HSD17B14 |
| 2.003e-02 | -3.91 | DCAF12L2 (DDB1 and CUL4 associated factor 12-like 2) | protein interactions | 340578 | 2 | 2 | 16036 | 2270 |
CUL4A,COPS6 |
| 2.003e-02 | -3.91 | TOM20 (Tom20p) | protein interactions | 852973 | 2 | 2 | 16036 | 2270 |
CSNK2A1,CSNK1A1 |
| 2.003e-02 | -3.91 | TSL1 (Tsl1p) | protein interactions | 854872 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | Myh10 (myosin, heavy polypeptide 10, non-muscle) | protein interactions | 77579 | 2 | 2 | 16036 | 2270 |
PBX1,SNCA |
| 2.003e-02 | -3.91 | BPY2 (basic charge, Y-linked, 2) | protein interactions | 9083 | 2 | 2 | 16036 | 2270 |
MAP1S,UBE3A |
| 2.003e-02 | -3.91 | SUI3 (translation initiation factor eIF2 subunit beta) | protein interactions | 855838 | 2 | 2 | 16036 | 2270 |
BZW2,UBC |
| 2.003e-02 | -3.91 | THR1 (homoserine kinase) | protein interactions | 856420 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | Scap (SREBF chaperone) | protein interactions | 235623 | 2 | 2 | 16036 | 2270 |
SREBF2,INSIG1 |
| 2.003e-02 | -3.91 | RPB4 (DNA-directed RNA polymerase II subunit RPB4) | protein interactions | 853301 | 2 | 2 | 16036 | 2270 |
BRCA1,UBC |
| 2.003e-02 | -3.91 | GLO4 (hydroxyacylglutathione hydrolase GLO4) | protein interactions | 854205 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | YMR226C (oxidoreductase) | protein interactions | 855266 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | WDR27 (WD repeat domain 27) | protein interactions | 253769 | 2 | 2 | 16036 | 2270 |
SHMT2,ASNS |
| 2.003e-02 | -3.91 | CEP112 (centrosomal protein 112kDa) | protein interactions | 201134 | 2 | 2 | 16036 | 2270 |
USP7,FUS |
| 2.003e-02 | -3.91 | HSP30 (Hsp30p) | protein interactions | 850385 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | BDH2 (3-hydroxybutyrate dehydrogenase, type 2) | protein interactions | 56898 | 2 | 2 | 16036 | 2270 |
SNCA,BDH2 |
| 2.003e-02 | -3.91 | GSP1 (Ran GTPase GSP1) | protein interactions | 851000 | 2 | 2 | 16036 | 2270 |
RANGAP1,UBC |
| 2.003e-02 | -3.91 | YRB1 (Ran GTPase-binding protein YRB1) | protein interactions | 851565 | 2 | 2 | 16036 | 2270 |
RAN,UBC |
| 2.003e-02 | -3.91 | SRD5A3 (steroid 5 alpha-reductase 3) | protein interactions | 79644 | 2 | 2 | 16036 | 2270 |
NUDT15,ADK |
| 2.003e-02 | -3.91 | rnf-5 (RING finger protein 5) | protein interactions | 175532 | 2 | 2 | 16036 | 2270 |
PXN,UBC |
| 2.003e-02 | -3.91 | ERI2 (ERI1 exoribonuclease family member 2) | protein interactions | 112479 | 2 | 2 | 16036 | 2270 |
DNAJC12,FLNC |
| 2.003e-02 | -3.91 | MET17 (bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17) | protein interactions | 851010 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | APE2 (Ape2p) | protein interactions | 853699 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | SUB1 (chromatin-binding transcription coactivator SUB1) | protein interactions | 855055 | 2 | 2 | 16036 | 2270 |
SUB1,BRCA1 |
| 2.003e-02 | -3.91 | ZNF177 (zinc finger protein 177) | protein interactions | 7730 | 2 | 2 | 16036 | 2270 |
SLC37A3,ARHGAP21 |
| 2.003e-02 | -3.91 | Trim3 (tripartite motif-containing 3) | protein interactions | 55992 | 2 | 2 | 16036 | 2270 |
ZFYVE28,SNCA |
| 2.003e-02 | -3.91 | Cdon (cell adhesion associated, oncogene regulated) | protein interactions | 50938 | 2 | 2 | 16036 | 2270 |
ABL1,SPAG9 |
| 2.003e-02 | -3.91 | LINC00152 (long intergenic non-protein coding RNA 152) | protein interactions | 112597 | 2 | 2 | 16036 | 2270 |
BANP,HSD17B14 |
| 2.003e-02 | -3.91 | BBC1 (Bbc1p) | protein interactions | 853433 | 2 | 2 | 16036 | 2270 |
BRCA1,UBC |
| 2.003e-02 | -3.91 | MIA40 (Mia40p) | protein interactions | 853639 | 2 | 2 | 16036 | 2270 |
UBC,CIAPIN1 |
| 2.003e-02 | -3.91 | CEP83 (centrosomal protein 83kDa) | protein interactions | 51134 | 2 | 2 | 16036 | 2270 |
CEP83,UBC |
| 2.003e-02 | -3.91 | NUP53 (FG-nucleoporin NUP53) | protein interactions | 855184 | 2 | 2 | 16036 | 2270 |
BRCA1,SNCA |
| 2.003e-02 | -3.91 | SBP1 (Sbp1p) | protein interactions | 856351 | 2 | 2 | 16036 | 2270 |
FUS,UBC |
| 2.003e-02 | -3.91 | Snca (synuclein, alpha) | protein interactions | 20617 | 2 | 2 | 16036 | 2270 |
CAV1,NEDD4 |
| 2.003e-02 | -3.91 | XRS2 (Xrs2p) | protein interactions | 851975 | 2 | 2 | 16036 | 2270 |
ATM,BRCA1 |
| 2.003e-02 | -3.91 | BFR1 (Bfr1p) | protein interactions | 854373 | 2 | 2 | 16036 | 2270 |
CASP10,UBC |
| 2.003e-02 | -3.91 | Tbx6 (T-box 6) | protein interactions | 21389 | 2 | 2 | 16036 | 2270 |
TCF3,UBC |
| 2.003e-02 | -3.91 | Myod1 (myogenic differentiation 1) | protein interactions | 17927 | 2 | 2 | 16036 | 2270 |
TCF3,KDM1A |
| 2.003e-02 | -3.91 | Per1 (period circadian clock 1) | protein interactions | 18626 | 2 | 2 | 16036 | 2270 |
TIMELESS,HIF1A |
| 2.003e-02 | -3.91 | Rxrb (retinoid X receptor beta) | protein interactions | 20182 | 2 | 2 | 16036 | 2270 |
NRIP1,UBC |
| 2.003e-02 | -3.91 | Usp19 (ubiquitin specific peptidase 19) | protein interactions | 71472 | 2 | 2 | 16036 | 2270 |
MARCH6,UBC |
| 2.003e-02 | -3.91 | CFAP65 (cilia and flagella associated protein 65) | protein interactions | 255101 | 2 | 2 | 16036 | 2270 |
CCNDBP1,GART |
| 2.003e-02 | -3.91 | ABCA10 (ATP binding cassette subfamily A member 10) | protein interactions | 10349 | 2 | 2 | 16036 | 2270 |
CUL4A,COPS5 |
| 2.003e-02 | -3.91 | OPI3 (bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase) | protein interactions | 853536 | 2 | 2 | 16036 | 2270 |
UBC,SNCA |
| 2.003e-02 | -3.91 | GPR143 (G protein-coupled receptor 143) | protein interactions | 4935 | 2 | 2 | 16036 | 2270 |
SUCLG2,GNAI1 |
| 2.003e-02 | -3.91 | TMEM25 (transmembrane protein 25) | protein interactions | 84866 | 77 | 18 | 16036 | 2270 |
BANP,NOMO3,TUBA1A,LPCAT2,ALDH1L2,HSPA5,TMEM132A,TCTN1,NAMPT,PAM,LARGE,ADAM9,WDR60,FUT11,GALNT18,CNTNAP3B,LAMA5,PCSK6 |
| 2.003e-02 | -3.91 | poly(A) binding | molecular function | GO:0008143 | 13 | 5 | 16491 | 2164 |
DDX3X,SYNCRIP,PABPC1,KHDRBS1,PABPC4 |
| 2.003e-02 | -3.91 | DNA-(apurinic or apyrimidinic site) lyase activity | molecular function | GO:0003906 | 13 | 5 | 16491 | 2164 |
ALKBH1,HMGA2,APEX1,APLF,OGG1 |
| 2.008e-02 | -3.91 | FHL1 (four and a half LIM domains 1) | protein interactions | 2273 | 35 | 10 | 16036 | 2270 |
SMAD3,DBN1,DEAF1,TTN,AKAP12,RBPJ,NRIP1,UBC,RING1,USP15 |
| 2.008e-02 | -3.91 | PPAT (phosphoribosyl pyrophosphate amidotransferase) | protein interactions | 5471 | 35 | 10 | 16036 | 2270 |
CARS,HPRT1,GART,G6PD,ATXN1,ARHGAP1,IMPDH2,TROVE2,PRPS1,CARM1 |
| 2.008e-02 | -3.91 | EVA1C (eva-1 homolog C (C. elegans)) | protein interactions | 59271 | 35 | 10 | 16036 | 2270 |
RETSAT,ABCA3,KIDINS220,FAM189B,DNAJC1,TYW1,NRP1,PDE3B,POM121,POLR3A |
| 2.008e-02 | -3.91 | SRP9 (signal recognition particle 9kDa) | protein interactions | 6726 | 35 | 10 | 16036 | 2270 |
GEMIN5,P3H1,S100A10,SRP68,MYC,GEMIN4,BMI1,AARS,SRP14,IPO11 |
| 2.008e-02 | -3.91 | GADD45GIP1 (growth arrest and DNA-damage-inducible, gamma interacting protein 1) | protein interactions | 90480 | 35 | 10 | 16036 | 2270 |
NIFK,TSR1,EIF3C,GADD45A,COPS5,PTRH2,TMEM177,UPF2,EXOSC4,MRPS30 |
| 2.008e-02 | -3.91 | mitochondrion organization | biological process | GO:0007005 | 548 | 88 | 16441 | 2138 |
IMMP2L,PTCD2,LETM1,RARS2,PPARGC1B,PRKAB2,AARS2,MRPL10,COA1,COX10,AMBRA1,MRPS30,MIEF1,BLOC1S2,NUBPL,NRF1,PMAIP1,ATG3,MRPS27,SSBP1,FXN,LONP1,HTRA2,TIMM50,CDC37,DPF3,GDAP1,SESN2,PDK1,ATG9A,HARS,MTIF2,COL4A3BP,MRRF,ATG12,MCL1,POLG2,FOXRED1,CXADR,STOML2,SNCA,TIMM44,TIMM17A,DNAJA3,ATG7,MPV17,FIS1,CLU,UQCC2,C10orf2,PID1,CHCHD10,ATG2B,OPA1,NOL3,TIMM10,GFM2,NDUFS7,YARS2,MRPS11,GATC,PMPCA,ANXA5,HARS2,MRPL21,MAP3K12,TOMM34,CAV2,DDHD1,TIMM8B,BCS1L,MRPS10,OBSCN,PDE2A,RHOT2,C19orf70,CHCHD6,UBC,MRPL36,MFN2,FGFBP1,AGTPBP1,HK2,EIF2S1,NDUFAF5,PEX13,NDUFS5,UQCC1 |
| 2.012e-02 | -3.91 | NUDCD2 (NudC domain containing 2) | protein interactions | 134492 | 40 | 11 | 16036 | 2270 |
TTC1,SRSF2,PXN,SSU72,ACD,PAFAH1B1,TPM1,PRMT5,IGBP1,PPIL3,RNF114 |
| 2.012e-02 | -3.91 | REACTOME_RNA_POL_III_TRANSCRIPTION | MSigDB lists | REACTOME_RNA_POL_III_TRANSCRIPTION | 33 | 9 | 17758 | 2279 |
POLR3D,POLR3E,POU2F1,POLR3B,GTF3C3,POLR1C,SNAPC4,SNAPC5,POLR3A |
| 2.012e-02 | -3.91 | MODULE_419 | MSigDB lists | MODULE_419 | 33 | 9 | 17758 | 2279 |
FLNC,TPM4,SVIL,MYH9,CORO1A,ENC1,VCL,FLNB,SPTAN1 |
| 2.015e-02 | -3.90 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 499 | 80 | 17758 | 2279 |
TRIM16,BTBD2,PTPRA,PPP2R2A,SSBP2,STAM,MAP2K3,MRPS30,BRE,GPR87,GSTA4,TUBA1A,ABCC4,SSFA2,SKAP2,GLTSCR2,LIMA1,PITPNB,MARCH6,ODC1,SAP30BP,MAT2A,GNAI1,PLIN2,MSRA,LSS,ALAD,DNAJC1,DCXR,ITGA2,ARNTL,CFD,BDH2,HSPB8,ABCC3,RPS6KB1,SCARB1,ZBTB11,LPP,VIPR1,HERC2,NCOR2,PIGN,SH2D3A,STX8,EGR1,B4GALT5,DBF4,SMAD7,VPS45,PDE4B,RCAN1,GAS6,PHGDH,RPS6KA5,RLF,FAM8A1,NAMPT,PRKCH,NEBL,RAPGEFL1,SPTAN1,FOXN3,TLE3,ARID1A,IL6R,PIK3CB,ANXA1,OXSR1,ATXN7,SPAG9,SYNCRIP,HIF1A,FSCN1,UBAP1,HERC1,LEMD3,HK2,PEX13,DDX10 |
| 2.017e-02 | -3.90 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR | 147 | 28 | 17758 | 2279 |
ACADS,MMRN2,CMIP,ATP6V1A,PSPC1,C2orf76,DLG4,LPCAT3,VIM,CPT1A,PITPNM1,ETFB,ECH1,MGST1,ZNF655,OXSR1,ETFDH,DECR1,HSDL2,TOM1L2,ACOX1,SEC24C,ORC5,HOXA3,CMPK1,ARC,COQ3,MAP3K12 |
| 2.019e-02 | -3.90 | BLM (Bloom syndrome, RecQ helicase-like) | protein interactions | 641 | 105 | 23 | 16036 | 2270 |
RREB1,ATRX,SIRT7,FANCD2,TOP3A,FAN1,SUMO3,TRIM15,BRCA1,MLH1,SUPT5H,RMI1,CHAF1A,RPA1,EXO1,PWP1,TP53BP1,COPS5,XRCC2,H2AFX,ATM,UPF2,TERF2 |
| 2.019e-02 | -3.90 | ligase activity, forming carbon-nitrogen bonds | molecular function | GO:0016879 | 54 | 13 | 16491 | 2164 |
CAD,GART,ASNS,MTHFD2,GATC,HLCS,FAAH2,PCCA,DPH6,LIAS,MTHFD1L,MTHFD2L,MTHFD1 |
| 2.028e-02 | -3.90 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090092 | 216 | 39 | 16441 | 2138 |
CHST11,SMAD7,NREP,ZIC2,TGFB2,TGFBR2,BMP6,SKI,FKBP1A,SNW1,UCHL5,ZEB1,RNF111,PEG10,ZC3H3,CAV2,DMRT1,PCSK6,FGF9,MSX1,PRDM16,HSPA5,CAV1,MEN1,ONECUT2,TCF7L2,UBC,DKK1,SKIL,SMAD3,MSX2,GATA6,PMEPA1,HIPK2,LEMD3,GLG1,RBPJ,BMP4,USP15 |
| 2.032e-02 | -3.90 | GSE17721_LPS_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDM_UP | 199 | 36 | 17758 | 2279 |
PIGM,PTPRA,NKD2,PCSK7,LETMD1,BHLHE40,TNKS1BP1,FAM8A1,SBDS,PTPN2,WAC,AP1M1,ACOT11,HTRA2,SEH1L,HN1,SAP30,VOPP1,GCNT2,PRIM2,PSAT1,TRA2A,AP4B1,TOR1AIP2,RSBN1,GNL1,CPT1A,C8orf33,TJAP1,RDH11,DYRK1B,KPNA3,PMEPA1,KLF4,TMEM219,APAF1 |
| 2.032e-02 | -3.90 | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP | 199 | 36 | 17758 | 2279 |
SARS,MCM6,SYT17,UBN1,CAMK1,TRIO,ISG20L2,INPP1,FOXO3,GIT2,PIP4K2A,PITPNM1,POM121,SIPA1L3,CAMTA2,SOCS1,TBC1D22A,ATXN2,VPS52,PTGS1,ZMYM2,SPTAN1,NARS,FOXN3,RNH1,EIF3H,MFN2,RERE,DDAH2,ZNF266,ADNP,WDR7,SGSM2,SLC25A11,PTP4A2,P2RY11 |
| 2.034e-02 | -3.90 | lipid metabolic process | biological process | GO:0006629 | 1158 | 174 | 16441 | 2138 |
GGT1,CYP24A1,PIGM,MVK,PRDX6,PRKAB2,TNFRSF21,CERS5,CACNA1H,SIRT2,ABHD6,SYNJ1,LPIN1,SREBF2,FAAH2,JAZF1,ME1,SLC27A5,PRKACB,CARM1,ACADS,CHD9,SESN2,PPARG,GPCPD1,GDPD1,COL4A3BP,CAV1,BRCA1,PITPNB,ST3GAL5,PLCXD2,OSBPL1A,LSS,INSIG1,GATA6,BDH2,TNFRSF1A,ABCC3,CLU,RBP1,LDAH,PIGN,ST6GAL1,GPAT3,PIK3R4,ALG8,HSD17B10,DPM3,PLA2G12A,PITPNM1,ETFB,PI4KB,ISPD,PIGG,VAPB,GLTP,SYNJ2,PNPLA3,LPCAT1,FDFT1,HSD17B14,HMGCR,FADS1,ALG6,ELOVL6,PCCA,RDH10,TBXAS1,SMARCD3,ST6GALNAC3,TPRA1,PLCB1,CPT1A,ANGPTL4,ACOXL,VAC14,RDH11,IRS1,CAT,DAGLA,FAM135A,FDPS,SLC16A1,SQLE,DPEP1,PEX13,BPNT1,TBL1X,NCOR1,GGT7,DHCR7,PDSS2,CPT1C,MPI,TRERF1,NPAS2,PAFAH1B1,LPCAT2,PIGH,TNXB,PBX1,LPCAT3,ST3GAL6,ARSJ,LCLAT1,FDX1,PDE3A,DECR1,IDI1,CBR4,LPIN2,PNPLA4,MGLL,HTRA2,LYST,PRPF19,MCEE,ACSL5,PI4KAP2,RAB7A,HSD3B7,SNCA,TAMM41,PLIN2,G6PD,PEMT,ABHD3,LARGE,SMG1,MORC2,SERINC5,NCOR2,INSIG2,LIAS,IP6K2,GDPD5,INPP1,PIP4K2A,SLC25A20,ADH5,PEX7,ACOT11,KDELC1,PTGS1,CPNE7,LYPLA2,HSD17B12,SLC25A1,MBTPS2,DDHD1,FGF2,AGPAT4,SULT4A1,PIK3CB,NAPEPLD,MMAA,NEU1,ECH1,SMPDL3B,TRIB3,RETSAT,ETFDH,ALG5,SERINC1,DAGLB,GPC2,ACOX1,SRD5A3,ATM,GPAM,PSAP,NR2F2,MTMR1 |
| 2.034e-02 | -3.90 | Propionyl-CoA catabolism | REACTOME pathways | R-HSA-71032 | 5 | 3 | 8202 | 1117 |
MCEE,PCCA,MMAA |
| 2.034e-02 | -3.90 | Reversal of alkylation damage by DNA dioxygenases | REACTOME pathways | R-HSA-73943 | 5 | 3 | 8202 | 1117 |
ASCC3,ASCC1,ALKBH3 |
| 2.035e-02 | -3.89 | ACTA1 (actin, alpha 1, skeletal muscle) | protein interactions | 58 | 175 | 35 | 16036 | 2270 |
TTN,CUL7,TRIP6,ACTG1,MYO7A,PRKCA,CSNK1A1,SMARCB1,ABL1,PRKCE,RRN3,UBE3A,CTNNBL1,SHC1,POLR1B,AMOT,VCL,HTRA2,SPTAN1,RPS6KB2,PPP1R9B,DNMBP,MYO10,HDAC8,VIM,COTL1,TMSB4X,ISG15,SNCA,FSCN1,ITGA2,RPS6KB1,TRAF3,XPO6,CORO2B |
| 2.035e-02 | -3.89 | MODULE_118 | MSigDB lists | MODULE_118 | 395 | 65 | 17758 | 2279 |
ADAM19,TRPM2,RIBC2,SLC2A1,GYG1,TTI1,RAC3,AP1M1,WIZ,CORO1A,CEP135,PEG10,MGLL,HTRA2,TRIP13,PRPF19,DBN1,RFC4,PRAME,COL5A2,PARP2,NPM3,GNG7,AKAP12,CAV1,SOX4,MCM2,DSP,FGFR1,CHAF1A,PLIN2,HPRT1,INSIG1,PER1,H2AFX,ADAM9,MAGI1,TPM1,TMEM158,RBP1,MCM6,FN1,UBXN1,PDE4B,ZIC2,TGFBR2,PHLDA2,IGF2BP3,DDIT4,SLC7A11,PTRF,MYC,MFAP2,CAV2,MYB,FADS1,EXOSC2,KCNQ3,CRIM1,MYO10,ZBED4,ARID1A,ISG15,ANXA1,FDPS |
| 2.044e-02 | -3.89 | MARSON_FOXP3_TARGETS_UP | MSigDB lists | MARSON_FOXP3_TARGETS_UP | 61 | 14 | 17758 | 2279 |
PLIN2,TNK2,ECM1,S100A10,OSBPL9,MYH9,MCL1,VIM,CORO1A,CD44,NRIP1,MBNL2,STK10,DDIT4 |
| 2.044e-02 | -3.89 | GCM_CRKL | MSigDB lists | GCM_CRKL | 61 | 14 | 17758 | 2279 |
HERC2,DYNC1H1,KDM3B,SPRED2,TSR1,GTF2A1,ANKRD17,MYO10,ZFP14,FAN1,RTN4,UBE2K,XPO6,SPIRE1 |
| 2.047e-02 | -3.89 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | 186 | 34 | 17758 | 2279 |
DNAJA4,CHST11,AUH,APRT,TMEM132A,RPS6KA5,CDC73,NEDD4,MAP2K3,KCTD11,RAP1A,ASNS,LYPLAL1,DNAJB6,MARVELD2,DSG2,NT5M,SKAP2,MYO10,LGALS1,RNH1,SLC35F2,PRDM1,EVI5,SMPDL3B,PLIN2,PMEPA1,DNAJC1,SLC4A7,CASS4,TAF12,RBPJ,BMI1,SLC16A10 |
| 2.047e-02 | -3.89 | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDM_DN | 186 | 34 | 17758 | 2279 |
PTCD2,SIRT7,HES6,RBM19,SEC16A,ABL1,SACS,UBE3A,CMPK1,POLE3,PLEKHA2,SF3A1,VOPP1,RREB1,ANKMY2,TOP3A,RAP1GDS1,MARCH6,SERP1,POLR3A,DHX57,MLLT10,MFN2,MGAT2,GADD45A,TP53BP1,EXOC4,RIOK3,AEN,DNAJC12,CRCP,WDR33,SRP14,KIF1B |
| 2.047e-02 | -3.89 | GSE17721_CTRL_VS_POLYIC_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_4H_BMDM_UP | 186 | 34 | 17758 | 2279 |
ESCO1,TNFRSF21,RFX1,SLC2A1,MLH1,LCLAT1,NDUFS7,RAP1A,ARMC6,C15orf40,CLCN6,SAMD4A,TMLHE,ELOF1,FDFT1,FAM98A,SLC40A1,TUBA1A,BAZ2A,RFX2,RABAC1,C1orf174,TMEM206,ECH1,TSR1,SSU72,COPS5,FDPS,DUSP19,SVIL,KLHDC4,PTP4A2,BRCC3,AP2S1 |
| 2.047e-02 | -3.89 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 186 | 34 | 17758 | 2279 |
ACTR3,MYH9,ZFP36L1,DENND3,MBNL1,EEA1,PHC2,PRKCE,SH2B3,ANKRD13A,RPS16,CCDC50,ATP5G2,MCM5,MYC,BANF1,METTL8,CELF1,ZNF518B,SNX29,SIK3,SETD2,ARID1A,DDX60,ZNF655,ATXN7,TASP1,RPL28,HNRNPR,KIAA0355,TAF4,SYNGR2,MDN1,C7orf26 |
| 2.047e-02 | -3.89 | GSE7852_LN_VS_FAT_TCONV_UP | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_UP | 186 | 34 | 17758 | 2279 |
ALG8,C14orf159,HES6,IGF2BP2,BCOR,SLC30A7,AHCYL1,N4BP2,TERF2,PCGF3,RREB1,STAG1,PDK1,RAPGEF4,RDH10,BCS1L,PSMG1,HIST1H2BL,TTC28,NCDN,RERE,PWP1,FBXL5,ZNF266,IREB2,CC2D1B,LRRC40,SOCS4,AEN,FNTB,RBM26,PREPL,SH3PXD2A,SMG1 |
| 2.047e-02 | -3.89 | Metabolism of porphyrins | REACTOME pathways | R-HSA-189445 | 17 | 6 | 8202 | 1117 |
HMBS,ALAD,HMOX2,COX10,CPOX,UROD |
| 2.047e-02 | -3.89 | Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | REACTOME pathways | R-HSA-176407 | 17 | 6 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 2.047e-02 | -3.89 | Translesion synthesis by POLK | REACTOME pathways | R-HSA-5655862 | 17 | 6 | 8202 | 1117 |
RFC4,RFC3,POLK,MAD2L2,UBC,RPA1 |
| 2.047e-02 | -3.89 | Phosphorylation of the APC/C | REACTOME pathways | R-HSA-176412 | 17 | 6 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 2.049e-02 | -3.89 | human chr3p21.31 | chromosome location | human chr3p21.31 | 86 | 15 | 26250 | 2590 |
CDCP1,SMARCC1,KIAA1143,MON1A,CELSR3,SETD2,KIF15,HYAL1,KLHL18,ATRIP,SHISA5,IP6K2,PLXNB1,SLC25A20,BSN |
| 2.050e-02 | -3.89 | collagen fibril organization | biological process | GO:0030199 | 38 | 10 | 16441 | 2138 |
P3H1,COL5A2,NF1,DDR2,TNXB,ANXA2,TGFB2,SERPINH1,FOXC1,MKX |
| 2.052e-02 | -3.89 | GSE2706_UNSTIM_VS_2H_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_UP | 173 | 32 | 17758 | 2279 |
KLHL24,ZNF292,PTCD2,ZNF786,DROSHA,ZHX3,DCP1B,RNASEH2B,CEP290,SLC38A2,HARS2,ZNF148,POLR3B,FBXO31,C12orf4,ZNF680,AP4B1,SETD2,NOL8,SPOP,WDR5B,KDM4B,KLF4,MKL2,BIVM,TNFRSF1A,GLG1,SLC25A19,RBM26,YEATS2,ZNF589,C12orf45 |
| 2.052e-02 | -3.89 | MODULE_197 | MSigDB lists | MODULE_197 | 173 | 32 | 17758 | 2279 |
ZNF254,TCF12,MCM6,CUL4A,EGR1,KHDRBS1,TOX4,SNW1,MYC,CORO1A,CDK6,SNAPC5,ZNF646,PMS1,ATF4,ZNF124,ZNF195,CDK4,KDM5A,RFX2,WDHD1,TBRG4,MEF2D,SOX4,RBBP8,HIF1A,TAF4,CEBPZ,BMI1,NOLC1,MID1,ZBTB24 |
| 2.060e-02 | -3.88 | FYRN | smart domains | SM00541 | 5 | 3 | 9131 | 1249 |
KMT2D,KMT2C,KMT2A |
| 2.060e-02 | -3.88 | AWS | smart domains | SM00570 | 5 | 3 | 9131 | 1249 |
NSD1,ASH1L,SETD2 |
| 2.060e-02 | -3.88 | CobW_C | smart domains | SM00833 | 5 | 3 | 9131 | 1249 |
CBWD1,CBWD6,CBWD5 |
| 2.060e-02 | -3.88 | DDT | smart domains | SM00571 | 5 | 3 | 9131 | 1249 |
BAZ1A,BAZ2B,BAZ2A |
| 2.060e-02 | -3.88 | BRK | smart domains | SM00592 | 5 | 3 | 9131 | 1249 |
SMARCA4,CHD7,CHD9 |
| 2.060e-02 | -3.88 | ZnF_Rad18 | smart domains | SM00734 | 5 | 3 | 9131 | 1249 |
RAD18,POLK,FAN1 |
| 2.062e-02 | -3.88 | ZHAN_MULTIPLE_MYELOMA_CD1_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_UP | 44 | 11 | 17758 | 2279 |
TRIB3,SESN2,VPS37A,SLC7A11,STC2,PCK2,CSTA,PHGDH,TBC1D16,RBP1,BATF3 |
| 2.062e-02 | -3.88 | BROWNE_HCMV_INFECTION_8HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_8HR_DN | 44 | 11 | 17758 | 2279 |
PLIN2,VDR,SMAD3,DST,SACS,TFCP2,XPC,MYC,ANKMY2,BMP4,NAV3 |
| 2.062e-02 | -3.88 | MODULE_125 | MSigDB lists | MODULE_125 | 44 | 11 | 17758 | 2279 |
RFC4,RFC3,MCM6,BRCA2,POLE2,PRIM2,POLA1,LIG4,SSBP1,RPA1,CHAF1A |
| 2.062e-02 | -3.88 | BURTON_ADIPOGENESIS_4 | MSigDB lists | BURTON_ADIPOGENESIS_4 | 44 | 11 | 17758 | 2279 |
RHOU,ZNF706,GART,UCHL5,ABCF2,H2AFX,LDHA,DPEP1,PEG10,ANGPTL4,BZW2 |
| 2.065e-02 | -3.88 | body morphogenesis | biological process | GO:0010171 | 49 | 12 | 16441 | 2138 |
MSX1,BRAF,ARID5B,MYH3,CSRNP1,ANKRD11,TGFB2,FLVCR1,TCF7L2,SKI,DKK1,KAT6A |
| 2.065e-02 | -3.88 | positive regulation of muscle tissue development | biological process | GO:1901863 | 49 | 12 | 16441 | 2138 |
EFNB2,FGF9,GATA6,FGF2,MKL2,ARNTL,RPS6KB1,RBPJ,BMP4,FGFR1,HMGCR,MEF2C |
| 2.068e-02 | -3.88 | translation factor activity, RNA binding | molecular function | GO:0008135 | 89 | 19 | 16491 | 2164 |
GTF2H3,EIF4E3,EIF3C,EIF3J,MTIF2,EIF4A2,AGO2,EIF2A,EIF5B,ABCF1,GFM2,EIF3H,DENR,EIF2S2,COPS5,EEFSEC,EIF2S1,ETF1,EIF2B3 |
| 2.068e-02 | -3.88 | ZF_C3H1 | prosite domains | PS50103 | 56 | 13 | 11866 | 1504 |
TOE1,DUS3L,HELZ,ZC3H18,ZFP36L1,RBM26,ZC3H8,MBNL2,CNOT4,ZC3H3,MBNL1,DHX57,ZC3H13 |
| 2.072e-02 | -3.88 | UMP biosynthesis | BIOCYC pathways | HUMAN_PWY-5686 | 2 | 2 | 907 | 131 |
CAD,UMPS |
| 2.072e-02 | -3.88 | 5-aminoimidazole ribonucleotide biosynthesis | BIOCYC pathways | HUMAN_PWY-6121 | 2 | 2 | 907 | 131 |
GART,PPAT |
| 2.072e-02 | -3.88 | epoxysqualene biosynthesis | BIOCYC pathways | HUMAN_PWY-5670 | 2 | 2 | 907 | 131 |
SQLE,FDFT1 |
| 2.072e-02 | -3.88 | epoxysqualene biosynthesis | BIOCYC pathways | META_PWY-5670 | 2 | 2 | 907 | 131 |
SQLE,FDFT1 |
| 2.072e-02 | -3.88 | proline biosynthesis | BIOCYC pathways | HUMAN_PROSYN-PWY | 2 | 2 | 907 | 131 |
ALDH18A1,PYCR1 |
| 2.072e-02 | -3.88 | tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate | BIOCYC pathways | META_PWY-6613 | 2 | 2 | 907 | 131 |
GART,MTHFD1 |
| 2.072e-02 | -3.88 | L-proline biosynthesis I | BIOCYC pathways | META_PROSYN-PWY | 2 | 2 | 907 | 131 |
ALDH18A1,PYCR1 |
| 2.072e-02 | -3.88 | tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate | BIOCYC pathways | HUMAN_PWY-6613 | 2 | 2 | 907 | 131 |
GART,MTHFD1 |
| 2.072e-02 | -3.88 | 5-aminoimidazole ribonucleotide biosynthesis I | BIOCYC pathways | META_PWY-6121 | 2 | 2 | 907 | 131 |
GART,PPAT |
| 2.074e-02 | -3.88 | NDUFS1 (NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)) | protein interactions | 4719 | 61 | 15 | 16036 | 2270 |
NDUFV1,SEC24C,TMEM126B,MYC,SIRT7,NDUFB5,RNF2,OPA1,CPT1A,RHOT2,ATP6V0D1,KDM1A,MTCH1,UBC,NDUFS7 |
| 2.074e-02 | -3.88 | DDB2 (damage-specific DNA binding protein 2) | protein interactions | 1643 | 61 | 15 | 16036 | 2270 |
POP1,ZBTB17,ABL1,CUL4A,COPS4,XPC,SUPT6H,COPS5,COPS3,MYC,BANF1,COPS7B,COPS6,ISG15,TOP1 |
| 2.075e-02 | -3.88 | Mismatch repair | KEGG pathways | ko03430 | 23 | 7 | 6908 | 881 |
EXO1,RFC4,MLH1,RFC3,SSBP1,MSH3,RPA1 |
| 2.075e-02 | -3.88 | Mismatch repair | KEGG pathways | hsa03430 | 23 | 7 | 6908 | 881 |
EXO1,RFC4,MLH1,RFC3,SSBP1,MSH3,RPA1 |
| 2.080e-02 | -3.87 | TGCTTTG,MIR-330 | MSigDB lists | TGCTTTG,MIR-330 | 320 | 54 | 17758 | 2279 |
EFNB2,TCF12,MAP2K5,LUZP1,PAFAH1B1,SMAD7,ID2,SMG7,BCOR,QSER1,CSNK1A1,RLF,MBNL1,GIGYF2,PAIP2,IGF2BP3,PHC2,RAP1A,RNF111,GTF2H1,LTN1,ETF1,CMPK1,AMOT,CDK6,SRPK2,GATAD2B,ANTXR2,GPM6A,GPHN,WDFY3,TEAD1,FOXN3,PCMT1,GNL1,MBNL2,PLCB1,FGFR1,MLLT10,SKIL,IQCH,LRP1B,SNAP23,SET,PTPN4,FNTB,GPAM,PDLIM5,BMI1,SH3PXD2A,KIF1B,CEP170,MTCH1,MEF2C |
| 2.084e-02 | -3.87 | regulation of cellular response to heat | biological process | GO:1900034 | 72 | 16 | 16441 | 2138 |
DNAJC2,NUP43,AKT1S1,NUP160,NUP214,HSPA1A,POM121,RPA1,HSPA1B,CAMK2D,RANBP2,NUP133,DNAJB6,ATM,SEH1L,BAG1 |
| 2.086e-02 | -3.87 | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | MSigDB lists | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | 67 | 15 | 17758 | 2279 |
CARS,GARS,ASNS,TUBA1A,GADD45A,CFD,DDR2,GSTA4,CLU,OASL,PCK2,CD44,GPNMB,ISG15,ANXA1 |
| 2.086e-02 | -3.87 | MODULE_438 | MSigDB lists | MODULE_438 | 67 | 15 | 17758 | 2279 |
DTNB,TRIM13,KRT7,STX1A,CCNT1,KIF5A,KIF5C,CORO1A,SNAP25,EVPL,SEPT5,DSP,LAMA5,MID1,MAPT |
| 2.087e-02 | -3.87 | KEGG_SPLICEOSOME | MSigDB lists | KEGG_SPLICEOSOME | 122 | 24 | 17758 | 2279 |
NAA38,PRPF38B,SART1,PRPF31,TRA2A,PLRG1,SF3A3,PPIL1,ZMAT2,HSPA1A,HSPA1B,PRPF40B,SNW1,SRSF2,CTNNBL1,PHF5A,BCAS2,BUD31,PQBP1,NCBP2,PRPF4,HNRNPM,SF3A1,PRPF19 |
| 2.089e-02 | -3.87 | stress granule assembly | biological process | GO:0034063 | 9 | 4 | 16441 | 2138 |
DDX3X,DYNC1H1,BICD1,ATXN2 |
| 2.089e-02 | -3.87 | endoplasmic reticulum tubular network organization | biological process | GO:0071786 | 9 | 4 | 16441 | 2138 |
USE1,RTN4,RAB10,TMEM33 |
| 2.089e-02 | -3.87 | negative regulation of thymocyte aggregation | biological process | GO:2000399 | 9 | 4 | 16441 | 2138 |
PTPN2,BMP4,KIAA0922,ZC3H8 |
| 2.089e-02 | -3.87 | L-serine metabolic process | biological process | GO:0006563 | 9 | 4 | 16441 | 2138 |
SHMT2,SDSL,PSAT1,PHGDH |
| 2.089e-02 | -3.87 | intraciliary retrograde transport | biological process | GO:0035721 | 9 | 4 | 16441 | 2138 |
IFT140,DYNC2H1,WDR35,IFT43 |
| 2.089e-02 | -3.87 | mitochondrion transport along microtubule | biological process | GO:0047497 | 9 | 4 | 16441 | 2138 |
MAP1S,RHOT2,KIF1B,MAPT |
| 2.089e-02 | -3.87 | miRNA metabolic process | biological process | GO:0010586 | 9 | 4 | 16441 | 2138 |
DROSHA,LIN28B,AGO2,DIS3L2 |
| 2.089e-02 | -3.87 | negative regulation of neurotransmitter secretion | biological process | GO:0046929 | 9 | 4 | 16441 | 2138 |
BRAF,RAP1A,NF1,RAP1B |
| 2.089e-02 | -3.87 | DNA dealkylation involved in DNA repair | biological process | GO:0006307 | 9 | 4 | 16441 | 2138 |
ALKBH1,ASCC3,ASCC1,ALKBH3 |
| 2.089e-02 | -3.87 | negative regulation of sprouting angiogenesis | biological process | GO:1903671 | 9 | 4 | 16441 | 2138 |
DLL4,MAP2K5,MMRN2,KLF4 |
| 2.089e-02 | -3.87 | negative regulation of multicellular organismal metabolic process | biological process | GO:0044252 | 9 | 4 | 16441 | 2138 |
IL6R,ERRFI1,PPARG,ARRDC3 |
| 2.089e-02 | -3.87 | regulation of alkaline phosphatase activity | biological process | GO:0010692 | 9 | 4 | 16441 | 2138 |
SMAD3,TGFB2,PPARGC1B,MEF2C |
| 2.089e-02 | -3.87 | negative regulation of T cell differentiation in thymus | biological process | GO:0033085 | 9 | 4 | 16441 | 2138 |
PTPN2,BMP4,KIAA0922,ZC3H8 |
| 2.089e-02 | -3.87 | establishment of mitochondrion localization, microtubule-mediated | biological process | GO:0034643 | 9 | 4 | 16441 | 2138 |
MAP1S,RHOT2,KIF1B,MAPT |
| 2.089e-02 | -3.87 | ribonucleoside biosynthetic process | biological process | GO:0042455 | 102 | 21 | 16441 | 2138 |
AK2,UPP1,ATP6V0A1,ADSL,APRT,CHCHD10,IMPDH2,MAT2A,ATP5D,STOML2,CAD,HPRT1,NME7,ATP5G2,SURF1,PPCDC,UMPS,CMPK1,ADK,PRPS1,NT5E |
| 2.089e-02 | -3.87 | REACTOME_DEADENYLATION_OF_MRNA | MSigDB lists | REACTOME_DEADENYLATION_OF_MRNA | 18 | 6 | 17758 | 2279 |
CNOT6,CNOT4,TNKS1BP1,PARN,PABPC1,EIF4A2 |
| 2.089e-02 | -3.87 | SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP | MSigDB lists | SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP | 18 | 6 | 17758 | 2279 |
ID2,EXOSC4,ID1,BHLHE40,DDIT3,GZF1 |
| 2.089e-02 | -3.87 | PODAR_RESPONSE_TO_ADAPHOSTIN_DN | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_DN | 18 | 6 | 17758 | 2279 |
IDI1,INSIG1,ACTG1,DHCR7,FDFT1,HK2 |
| 2.089e-02 | -3.87 | DNA_POLYMERASE_ACTIVITY | MSigDB lists | DNA_POLYMERASE_ACTIVITY | 18 | 6 | 17758 | 2279 |
POLB,POLE3,POLE2,DKC1,POLG2,POLA1 |
| 2.089e-02 | -3.87 | chr16q21 | MSigDB lists | chr16q21 | 18 | 6 | 17758 | 2279 |
CCDC113,NOL3,GINS3,SETD6,E2F4,NDRG4 |
| 2.089e-02 | -3.87 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | MSigDB lists | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | 18 | 6 | 17758 | 2279 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 2.089e-02 | -3.87 | YIH_RESPONSE_TO_ARSENITE_C2 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C2 | 18 | 6 | 17758 | 2279 |
TCF12,ABL1,MCL1,GADD45A,TANK,NIT1 |
| 2.089e-02 | -3.87 | MITOCHONDRIAL_OUTER_MEMBRANE | MSigDB lists | MITOCHONDRIAL_OUTER_MEMBRANE | 18 | 6 | 17758 | 2279 |
FIS1,MCL1,OPA1,RHOT2,TOMM34,MFN2 |
| 2.089e-02 | -3.87 | BIOCARTA_TNFR2_PATHWAY | MSigDB lists | BIOCARTA_TNFR2_PATHWAY | 18 | 6 | 17758 | 2279 |
RIPK1,TRAF3,MAP3K14,IKBKAP,TANK,IKBKB |
| 2.089e-02 | -3.87 | NAGY_TFTC_COMPONENTS_HUMAN | MSigDB lists | NAGY_TFTC_COMPONENTS_HUMAN | 18 | 6 | 17758 | 2279 |
TADA3,TAF2,ATXN7,TRRAP,TAF12,TAF4 |
| 2.089e-02 | -3.87 | NUCLEOTIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | NUCLEOTIDE_BIOSYNTHETIC_PROCESS | 18 | 6 | 17758 | 2279 |
UMPS,ME1,HPRT1,CMPK1,PPAT,ADK |
| 2.091e-02 | -3.87 | PlsC | smart domains | SM00563 | 17 | 6 | 9131 | 1249 |
GPAM,LPCAT1,LCLAT1,AGPAT4,LPCAT2,GPAT3 |
| 2.094e-02 | -3.87 | Type 2 diabetes(PMID:17463248) | GWAS genes | Type 2 diabetes(PMID:17463248) | 7 | 4 | 2389 | 419 |
CDKAL1,IGF2BP2,PPARG,TCF7L2 |
| 2.094e-02 | -3.87 | Metabolic syndrome(PMID:20694148) | GWAS genes | Metabolic syndrome(PMID:20694148) | 7 | 4 | 2389 | 419 |
FADS1,GIT2,TCF7L2,HERPUD1 |
| 2.094e-02 | -3.87 | QT interval(PMID:20031603) | GWAS genes | QT interval(PMID:20031603) | 7 | 4 | 2389 | 419 |
TTN,PTPRG,ARHGAP10,PDE3A |
| 2.094e-02 | -3.87 | Pulmonary function(PMID:20010835) | GWAS genes | Pulmonary function(PMID:20010835) | 7 | 4 | 2389 | 419 |
INTS12,ADAM19,FAM13A,ADGRG6 |
| 2.096e-02 | -3.87 | human chr3q21 | chromosome location | human chr3q21 | 17 | 5 | 26250 | 2590 |
ZNF148,KPNA1,MCM2,CSTA,MYLK-AS1 |
| 2.098e-02 | -3.86 | Drf_FH3 | pfam domains | PF06367 | 9 | 4 | 16629 | 2165 |
FMNL3,INF2,FMNL1,FMNL2 |
| 2.098e-02 | -3.86 | MCM | pfam domains | PF00493 | 9 | 4 | 16629 | 2165 |
MCM6,MCM2,MCM9,MCM5 |
| 2.098e-02 | -3.86 | RAWUL | pfam domains | PF16207 | 9 | 4 | 16629 | 2165 |
PCGF3,RNF2,BMI1,RING1 |
| 2.098e-02 | -3.86 | Beach | pfam domains | PF02138 | 9 | 4 | 16629 | 2165 |
NBEA,NBEAL1,WDFY3,LYST |
| 2.098e-02 | -3.86 | Radical_SAM | pfam domains | PF04055 | 9 | 4 | 16629 | 2165 |
CDKAL1,LIAS,ELP3,TYW1 |
| 2.098e-02 | -3.86 | MIF4G | pfam domains | PF02854 | 9 | 4 | 16629 | 2165 |
UPF2,MIF4GD,CTIF,NOM1 |
| 2.098e-02 | -3.86 | Methyltransf_11 | pfam domains | PF08241 | 9 | 4 | 16629 | 2165 |
NDUFAF5,ALKBH8,CIAPIN1,WBSCR22 |
| 2.098e-02 | -3.86 | Drf_GBD | pfam domains | PF06371 | 9 | 4 | 16629 | 2165 |
FMNL3,INF2,FMNL1,FMNL2 |
| 2.103e-02 | -3.86 | BERENJENO_TRANSFORMED_BY_RHOA_UP | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_UP | 521 | 83 | 17758 | 2279 |
SRM,FEZ2,DDX18,SLC2A1,RSL1D1,TUBB6,FLNB,TOM1L1,PHC2,RPP30,RRN3,PHF5A,PPID,UCHL5,ETF1,FTSJ3,TRIP13,CASP8AP2,TMPO,SAP30,ACSL5,PHLDB2,RFC4,TNK2,RFC3,HARS,EIF3J,WDHD1,BRCA1,MCM2,SLC35D1,ODC1,MAK16,TAMM41,EXO1,HPRT1,KLF4,TRAF3,RUNX1,EFNB2,HMGA2,SEPHS2,DNAJC2,MCM10,TTC27,SLK,SF3A3,VARS,DCTPP1,GART,MYC,MCM5,BANF1,TIMELESS,PTGS1,ERRFI1,FBL,CD44,POLR1E,PPA1,IFRD1,BDNF,NAA38,PRIM2,PSAT1,POLA1,ABCF2,HAUS6,LDHA,PSMA1,USP10,MRPS10,RANGAP1,NOP58,RPA1,RARS,MTHFD2,PDLIM1,GADD45A,POLE2,HK2,GPN1,EIF2S1 |
| 2.107e-02 | -3.86 | NELSON_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | NELSON_RESPONSE_TO_ANDROGEN_UP | 85 | 18 | 17758 | 2279 |
DCTN3,CAMKK2,ABCC4,SEC24D,HOMER2,ARID5B,HES6,ID2,AKAP12,SNAP25,IQGAP2,IDI1,PMEPA1,KLF4,SLC38A2,FKBP5,PDLIM5,HSD17B14 |
| 2.108e-02 | -3.86 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 73 | 16 | 17758 | 2279 |
HERC2,SIK3,STAMBP,COL4A3BP,MAPK8IP3,RTN4,ATG2B,PTK2,ABHD6,NAPEPLD,ARHGAP21,MKL2,GLTP,CLDND1,ZNF710,PREPL |
| 2.109e-02 | -3.86 | negative regulation of cysteine-type endopeptidase activity | biological process | GO:2000117 | 96 | 20 | 16441 | 2138 |
MAP2K5,PAX2,CSNK2A1,RIPK1,GAS6,NOL3,NLE1,BIRC2,HERPUD1,SNCA,DDX3X,SH3RF1,DNAJB6,DNAJA3,KLF4,TRIAP1,DPEP1,TNFRSF10D,CD44,IGBP1 |
| 2.109e-02 | -3.86 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | 1322 | 194 | 17775 | 2278 |
CUL7,ACTG1,UBN1,NAT10,ENAH,ANKRD18A,ADAMTS6,IKBIP,NUP160,SNAPC4,SCAF8,PCDH7,SMARCB1,ZNF804A,SRSF2,ZFHX3,YLPM1,AP1M1,VPS52,ZNF148,KIAA0922,SLC27A5,SLC35C2,SRRM2,ETV1,TBC1D8,PTPRK,LAMA4,GPM6A,SESN2,NRAS,HARS,BAZ2A,KLHL23,SKIV2L2,GNL3,ANK2,VWCE,RFX2,EFHC1,SEMA3F,BRCA1,DDX60,GZF1,GNAI1,BSN,CCDC3,UBTF,AHNAK,CHD3,CSMD3,DPP4,DNAH2,NMD3,EFNB2,CLDN15,JUP,CELSR1,ITFG1,PAX2,TRIO,CCDC47,KCNJ14,TGFBR2,HVCN1,CEP290,MCM5,WDR27,MYC,BUD31,NOM1,COL17A1,LAMC1,MYO10,USP49,RAP1GAP2,IDH3G,ZNF512B,BCS1L,RYR2,WWC1,OBSCN,PRDM1,CORIN,PHF6,LRP1B,RPL28,NME7,PMEPA1,VCAN,SPEN,ZZEF1,FAT1,FDPS,ZCCHC6,ZNF430,KIAA1328,C7orf50,KIAA0196,NCOR1,COG5,USP7,SPRED2,CYLD,ASH1L,PCNT,ATP6V1A,URB2,C16orf45,SPRYD7,SMARCA4,MYH9,SPATS2,PTPRG,PABPC1L,TNKS1BP1,PPP1R9A,DDX60L,PAG1,FLNB,PLXNB1,NOP56,CAD,CD96,PRKD3,KDM2A,ABCA12,SOCS1,GRIN2C,SNTG2,ANKRD24,C16orf58,SHF,CCDC40,MYH15,FHIT,SERPINH1,KMT2A,GNG5,CASP10,LYST,ZCCHC14,KMT2D,COL5A2,SSFA2,FAM111B,KIAA1586,ENC1,DSP,TTC28,STK10,PLIN2,MSX2,ARHGAP21,ASTN2,ATG7,LARGE,MDN1,NFASC,USP11,LAMA5,MUTYH,UNC13D,DMGDH,TNIK,BRAF,ESCO1,RFX1,SOGA1,GDPD5,CSNK1A1,SACS,NEBL,SCN1B,DDX31,LDLRAD3,PLEKHG4,NAV3,TTPAL,LRRIQ1,MON1A,CRIM1,ZNF324B,C11orf49,NAALADL2,CASC1,POLR3A,PXDN,HELZ,HNRNPH3,ATM,MYOM2,SORCS2,POLR1C |
| 2.109e-02 | -3.86 | plasma_cell_myeloma | COSMIC cancer mutations | plasma_cell_myeloma | 1322 | 194 | 17775 | 2278 |
CUL7,ACTG1,UBN1,NAT10,ENAH,ANKRD18A,ADAMTS6,IKBIP,NUP160,SNAPC4,SCAF8,PCDH7,SMARCB1,ZNF804A,SRSF2,ZFHX3,YLPM1,AP1M1,VPS52,ZNF148,KIAA0922,SLC27A5,SLC35C2,SRRM2,ETV1,TBC1D8,PTPRK,LAMA4,GPM6A,SESN2,NRAS,HARS,BAZ2A,KLHL23,SKIV2L2,GNL3,ANK2,VWCE,RFX2,EFHC1,SEMA3F,BRCA1,DDX60,GZF1,GNAI1,BSN,CCDC3,UBTF,AHNAK,CHD3,CSMD3,DPP4,DNAH2,NMD3,EFNB2,CLDN15,JUP,CELSR1,ITFG1,PAX2,TRIO,CCDC47,KCNJ14,TGFBR2,HVCN1,CEP290,MCM5,WDR27,MYC,BUD31,NOM1,COL17A1,LAMC1,MYO10,USP49,RAP1GAP2,IDH3G,ZNF512B,BCS1L,RYR2,WWC1,OBSCN,PRDM1,CORIN,PHF6,LRP1B,RPL28,NME7,PMEPA1,VCAN,SPEN,ZZEF1,FAT1,FDPS,ZCCHC6,ZNF430,KIAA1328,C7orf50,KIAA0196,NCOR1,COG5,USP7,SPRED2,CYLD,ASH1L,PCNT,ATP6V1A,URB2,C16orf45,SPRYD7,SMARCA4,MYH9,SPATS2,PTPRG,PABPC1L,TNKS1BP1,PPP1R9A,DDX60L,PAG1,FLNB,PLXNB1,NOP56,CAD,CD96,PRKD3,KDM2A,ABCA12,SOCS1,GRIN2C,SNTG2,ANKRD24,C16orf58,SHF,CCDC40,MYH15,FHIT,SERPINH1,KMT2A,GNG5,CASP10,LYST,ZCCHC14,KMT2D,COL5A2,SSFA2,FAM111B,KIAA1586,ENC1,DSP,TTC28,STK10,PLIN2,MSX2,ARHGAP21,ASTN2,ATG7,LARGE,MDN1,NFASC,USP11,LAMA5,MUTYH,UNC13D,DMGDH,TNIK,BRAF,ESCO1,RFX1,SOGA1,GDPD5,CSNK1A1,SACS,NEBL,SCN1B,DDX31,LDLRAD3,PLEKHG4,NAV3,TTPAL,LRRIQ1,MON1A,CRIM1,ZNF324B,C11orf49,NAALADL2,CASC1,POLR3A,PXDN,HELZ,HNRNPH3,ATM,MYOM2,SORCS2,POLR1C |
| 2.109e-02 | -3.86 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | 1094 | 163 | 17758 | 2279 |
PTP4A1,CUL4A,UBN1,TNFRSF21,MFGE8,CHAC1,CCNL2,IKBIP,TMEM132A,SLC6A8,AHCYL2,LPIN1,MAP2K3,ECM1,ATG3,SLC39A7,HYAL1,PAK1IP1,POLE3,FTSJ3,TBC1D8,SF3A1,GCNT2,FBXW4,SESN2,EIF4E3,ITPA,PTPRM,UPP1,ATOX1,MARCKSL1,MCL1,SHISA5,COTL1,SOX4,SGK2,FLVCR1,DDX60,MAK16,SAP30BP,ZNF622,AHNAK,TRMT5,TMEM158,ZMAT3,SLC12A7,EFNB2,SEPHS2,DCTN3,EPM2AIP1,C9orf78,EGR1,JUP,ANKRD17,FAM189B,SIRT7,HES6,PLA2G12A,PHGDH,PITPNM1,FAM192A,HR,NDRG4,CTR9,ATP6V0D1,PPA1,RABEPK,COL17A1,WDR61,IFNGR2,TRA2A,RDH10,MAP7D1,TPRA1,ISG15,UBE2E1,MGAT2,GTF2A1,PDLIM1,EXOC4,ZCCHC6,NAPA,PDLIM5,C12orf45,SRP14,FAM207A,PSTPIP2,PDK4,OLA1,GRINA,PLEK2,SLC25A44,HSPA1A,DENR,VPS18,KCTD11,GSTA4,CORO1A,NAA35,PLEKHA4,PERP,HN1,SAP30,MCEE,C1QTNF1,CPOX,LRRC8A,SLC35D1,PLIN2,YIPF2,LMBR1L,ALAD,DCXR,METTL6,ARNTL,SCARB1,BAG1,TTC27,RCAN1,CHCHD10,ZNF346,PHLDA2,FAM8A1,PSMF1,SFI1,POM121,POLR3D,FAM50A,PTRF,NOP16,SCN1B,PMPCA,SHMT2,CLDND1,C12orf4,AP4S1,KDM5B,POLK,SMARCAD1,PSMC3IP,ARHGAP39,TOP3A,NXN,SCMH1,IL6R,OASL,POLR2A,HSPA1B,KLHL22,RETSAT,ETFDH,GADD45A,ZBTB8OS,HERC1,AGTPBP1,VPS37B,USP20,AEN,APAF1,ITGB4,NUDT22,ARHGAP27,DDIT3 |
| 2.112e-02 | -3.86 | NUCLEAR_HORMONE_RECEPTOR_BINDING | MSigDB lists | NUCLEAR_HORMONE_RECEPTOR_BINDING | 28 | 8 | 17758 | 2279 |
NSD1,PPARGC1B,JMJD1C,MED24,SMARCD3,MED16,OASL,NRIP1 |
| 2.112e-02 | -3.86 | KEGG_HOMOLOGOUS_RECOMBINATION | MSigDB lists | KEGG_HOMOLOGOUS_RECOMBINATION | 28 | 8 | 17758 | 2279 |
BRCA2,XRCC2,RAD51B,TOP3A,EME1,SSBP1,RPA1,RAD54B |
| 2.113e-02 | -3.86 | V$E2F_Q4_01 | MSigDB lists | V$E2F_Q4_01 | 226 | 40 | 17758 | 2279 |
MCM6,ZCCHC8,MAP3K13,PIK3R4,RPS6KA5,PCDH7,DCTPP1,ZNF827,SRSF2,INTS7,ATP5G2,MYC,PDS5B,KIAA0922,ZMYM2,DMRT1,CASP8AP2,IPO11,SERBP1,TOP1,PPP1R9B,GINS3,STAG1,SLC38A1,USP49,POLA1,C19orf43,ABCF2,IMPDH2,MCM2,DLST,MAT2A,POLE2,SSU72,ZBTB8OS,TBX3,CSRNP1,TRMT2A,RBPJ,SMG1 |
| 2.114e-02 | -3.86 | SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP | MSigDB lists | SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP | 79 | 17 | 17758 | 2279 |
RFC4,MCM6,ALG6,CELSR3,FAM111B,RIBC2,NDUFB5,KIF15,TBCCD1,MYNN,MLH1,HLTF,MCM2,OPA1,RMI1,RAD18,NR2C2AP |
| 2.116e-02 | -3.86 | GSE17721_LPS_VS_CPG_0.5H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_0.5H_BMDM_UP | 193 | 35 | 17758 | 2279 |
LETM1,FAM207A,DDX18,TFIP11,CD99L2,CHCHD10,RTN1,ZFHX3,ATXN2,TANK,IKBKB,SLC38A2,COPS7B,LYRM5,ZNF518B,MTHFD1,ACADS,GNL3,IMPDH2,TPRA1,RBM28,DDX49,NCDN,TIMM44,RPA1,PRPF40B,LSS,ALAD,DNAJC1,PQBP1,NCOR1,RFXAP,ZNF598,GPATCH4,PARD3 |
| 2.116e-02 | -3.86 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | 193 | 35 | 17758 | 2279 |
CELSR1,PAFAH1B1,RNF24,SSBP2,SLC25A44,MFHAS1,SH2B3,S100A10,NOP16,PVRL3,TNPO3,BCAP29,FBXO31,HTRA2,TOP1,GARS,ZNF654,LGALS1,FERMT2,MARCH6,PITPNB,GPNMB,TPRA1,PDE2A,EIF5B,SAP30BP,TARS,SNCA,PWP1,RBBP8,KIDINS220,DSC2,SERINC1,LARGE,ANXA2 |
| 2.116e-02 | -3.86 | GSE17721_0.5H_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_CPG_BMDM_UP | 193 | 35 | 17758 | 2279 |
ZNF706,MYCBP2,PPARGC1B,ZFP36L1,CHCHD10,APRT,GYG1,SSBP2,CMTM3,ETFB,LPIN1,IQGAP2,ATP5G2,ATG3,PTGS1,POLE3,SLC35C2,IL11RA,CDK4,RAB7A,GNL3,PPP1R21,LGALS1,SOX4,ODC1,C19orf70,BATF3,HLA-DMA,VDR,DAGLB,KLF4,VPS37B,TNFRSF1A,HMBS,TXN2 |
| 2.116e-02 | -3.86 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN | 193 | 35 | 17758 | 2279 |
DCTN3,PRDX6,PDK4,PLA2G12A,TUBB6,RIOK2,SLC30A7,RAP1A,MYC,MMP14,ETF1,MFAP2,PPA1,IFRD1,ATF4,SLC3A2,SSFA2,EIF3J,HSPA5,GDPD1,HOMER2,LAMA2,ANGPTL4,SLC23A2,PGD,PLIN2,RHOU,OXSR1,SLC39A14,KPNA1,PMEPA1,ARNTL,MYOM2,POLR1C,PRKAR2A |
| 2.116e-02 | -3.86 | GSE17721_PAM3CSK4_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_6H_BMDM_UP | 193 | 35 | 17758 | 2279 |
SEPHS2,PTCD2,SARS,SPRED2,WDR13,SIRT7,PRAF2,LPCAT3,PRPF39,POLR3D,RPS16,GATC,BCAS2,NOP16,GTF2H1,TSPAN14,TMLHE,ELOF1,SRPK2,XPO5,R3HDM1,ADSL,COTL1,AGAP1,EVI5,MFN2,MLLT10,BATF3,HSPB8,SVIL,TRMT2A,SENP3,DHCR7,FAM118A,LPP |
| 2.116e-02 | -3.86 | GSE17721_POLYIC_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_2H_BMDM_UP | 193 | 35 | 17758 | 2279 |
SLC12A7,SEPHS2,LUZP1,SIRT7,PIBF1,ABL1,COMMD9,ANKRD13A,ATP5G2,NUP133,CBR4,FGGY,MYC,C15orf40,NDRG4,HARS2,GLTP,KIAA0922,LYRM5,PRPS1,CLK2,KDM3B,ITPA,KDM5A,FZD3,COL4A3BP,ZNFX1,METTL22,SOX4,DHX57,TBPL1,ARHGAP12,BAG1,ANAPC4,NR2C2AP |
| 2.117e-02 | -3.86 | NK-T_cell_lymphoma | COSMIC cancer mutations | NK-T_cell_lymphoma | 233 | 41 | 17775 | 2278 |
DMXL2,CACNA1H,DHX35,YARS2,IGSF1,ZNF608,NAV1,SIPA1L3,SLX4,FUT11,NUDC,NRAS,TTLL5,CRIM1,THSD4,SETD2,GRHL3,NLN,ATP6V0A1,WWC1,BRCA1,PRDM1,LAMA2,EDEM2,PPIP5K2,PLCB1,MMAA,BTBD11,DDX3X,GRIK4,FAM135A,GSTO2,ADNP,EXOC4,CTAGE5,VPS13D,ATM,CSMD3,HEATR1,IPO4,LMBRD2 |
| 2.124e-02 | -3.85 | FA58C | interpro domains | IPR000421 | 23 | 7 | 18293 | 2341 |
BTBD9,NRP1,CNTNAP3,CNTNAP3B,MFGE8,DCBLD2,DDR2 |
| 2.126e-02 | -3.85 | SART3 (squamous cell carcinoma antigen recognized by T-cells 3) | protein interactions | 9733 | 83 | 19 | 16036 | 2270 |
PRPF31,SIRT6,SIRT7,ARHGEF10,VARS,NUP160,UBR4,UBC,CMSS1,SRBD1,HIF1A,CDK9,COPS5,DSG2,RNF2,PRPF4,BMI1,AMOT,USP15 |
| 2.126e-02 | -3.85 | PRPF6 (pre-mRNA processing factor 6) | protein interactions | 24148 | 83 | 19 | 16036 | 2270 |
SART1,SNU13,CUL7,DDX18,PRPF31,TRA2A,SIRT7,SF3A3,SON,GIGYF2,RPA1,TIMM44,MYC,ZNF326,PRPF4,SRRM2,HNRNPM,SF3A1,PRPF19 |
| 2.129e-02 | -3.85 | BMPR1B (bone morphogenetic protein receptor type IB) | protein interactions | 658 | 72 | 17 | 16036 | 2270 |
EVA1C,TTC27,STAMBP,CDK4,UBXN1,SMAD7,BMP6,IGSF1,CHN1,OXSR1,SOCS6,PPP3CC,RAN,BMP4,TTC17,PEG10,USP15 |
| 2.129e-02 | -3.85 | GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN | 180 | 33 | 17758 | 2279 |
KCTD7,OXNAD1,ARL15,HECTD3,GTF2IRD1,DPM3,NUP43,PDCD7,REEP5,GIGYF2,POGZ,YARS2,PUS3,SACS,HIRIP3,RDX,ZFP37,PNMA1,HTRA2,SPTAN1,MCEE,ELP3,PPP1R21,TPRA1,PDE2A,ZNF407,NAPEPLD,SPOP,C1orf122,HSPBAP1,TIMM17A,FNTB,PRKAR2A |
| 2.129e-02 | -3.85 | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | 180 | 33 | 17758 | 2279 |
NCOR2,RBM33,SMAD7,NECAP1,AKT1S1,XPO7,DHX35,VPS18,SH2B3,ABL1,FMNL1,UBAP2L,GLTP,ITGAX,ZNF3,DENND1A,PXN,KDM5B,ATG9A,USP42,ZBED4,CUX1,MAP7D1,MEF2D,SUPT5H,NUDT15,GZF1,VPS37B,XPNPEP1,PPP1R12B,PURB,ANKS1A,LPP |
| 2.134e-02 | -3.85 | AKT1 (v-akt murine thymoma viral oncogene homolog 1) | protein interactions | 207 | 285 | 53 | 16036 | 2270 |
NCOR2,CYLD,BRAF,FOXO1,PPARGC1B,SMAD7,ARFIP2,CSNK2A1,ZFP36L1,AKT1S1,FOXO3,PLXNB1,NEDD4,PDE3A,SMARCB1,SKI,TERF2IP,IKBKB,TTC3,PPA1,CDC37,CLK2,METTL1,PEA15,TNK2,TRIM13,PDK1,SIRT6,HSPA5,TPM4,PREX1,LDHA,ATXN1,VIM,ARHGAP32,BRCA1,IMPDH2,PDE3B,PIK3CB,SNCA,SMAD3,IRS1,TRIB3,AHNAK,SMARCC1,NSF,SH3RF1,FKBP5,RPS6KB1,MAP2K4,MAPT,STK4,KAT6A |
| 2.139e-02 | -3.84 | ovary-carcinoma-mixed_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mixed_carcinoma | 23 | 7 | 17775 | 2278 |
ATM,RNF43,BRCA2,BRAF,BRCA1,MLH1,MAP2K4 |
| 2.139e-02 | -3.84 | BLOC1S2 (biogenesis of lysosomal organelles complex-1, subunit 2) | protein interactions | 282991 | 21 | 7 | 16036 | 2270 |
BCAS4,HMOX2,C8orf33,BLOC1S4,OSBPL9,DTNBP1,RDH11 |
| 2.139e-02 | -3.84 | Cdc23 (CDC23 cell division cycle 23) | protein interactions | 52563 | 21 | 7 | 16036 | 2270 |
ANAPC1,CFAP97,CDC16,ANAPC13,ANAPC4,ANAPC11,ANAPC10 |
| 2.139e-02 | -3.84 | DEGS1 (delta(4)-desaturase, sphingolipid 1) | protein interactions | 8560 | 21 | 7 | 16036 | 2270 |
SLC16A1,SIRT2,EIF5B,SUPT6H,LSG1,TSSC1,NT5E |
| 2.139e-02 | -3.84 | HIST1H4I (histone cluster 1, H4i) | protein interactions | 8294 | 21 | 7 | 16036 | 2270 |
SHMT2,CUL7,FN1,UCHL5,COPS5,CUL2,KAT6A |
| 2.139e-02 | -3.84 | TRPV5 (transient receptor potential cation channel, subfamily V, member 5) | protein interactions | 56302 | 21 | 7 | 16036 | 2270 |
PUS1,ANXA2,UBE3A,S100A10,PSPC1,RNF138,USP15 |
| 2.139e-02 | -3.84 | FOXR1 (forkhead box R1) | protein interactions | 283150 | 21 | 7 | 16036 | 2270 |
BANP,EP400,TRRAP,VPS72,MYC,MBTD1,PPCDC |
| 2.139e-02 | -3.84 | GALE (UDP-galactose-4-epimerase) | protein interactions | 2582 | 21 | 7 | 16036 | 2270 |
GALK2,PXN,ASNS,FN1,TSTA3,ITPA,GALE |
| 2.139e-02 | -3.84 | SETD2 (SET domain containing 2) | protein interactions | 29072 | 21 | 7 | 16036 | 2270 |
SMAD3,ATXN1,WDR37,SETD2,POLR2A,CLK2,ARHGEF10 |
| 2.140e-02 | -3.84 | ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN | MSigDB lists | ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN | 341 | 57 | 17758 | 2279 |
MVK,ACTG1,DDX18,CAMK1,UROD,CACNA1H,CD99L2,CHCHD10,PLEK2,PHGDH,ABHD6,AARS,PSMF1,MRPS11,ANXA10,SRPRB,SH2B3,NPRL2,SREBF2,ARMC6,FGGY,LPIN2,SHMT2,PCOLCE2,POLE3,PRADC1,SAMD4A,LONP1,SERBP1,SLC25A1,HMGCR,HSD17B14,SPTAN1,ZCCHC14,EVL,HSPA5,ABCC2,TBC1D16,CYB5B,SLC50A1,HSD3B7,RETSAT,TRRAP,KPNA1,SSU72,UBAP1,ZNF330,CDK9,VPS37B,TSSC1,TNFRSF1A,MYOM2,CENPBD1,TBL1X,MACROD1,CNDP2,ARHGAP10 |
| 2.140e-02 | -3.84 | GCANCTGNY_V$MYOD_Q6 | MSigDB lists | GCANCTGNY_V$MYOD_Q6 | 863 | 131 | 17758 | 2279 |
GNB3,BCAS4,TNFRSF21,PPARGC1B,AARS2,TMEM109,NBEAL1,DST,SREBF2,ZFHX3,MYH3,METTL8,VPS52,ZEB1,ETV1,ZMYM2,PTPRK,SRPK2,DPF3,NRAS,TXLNG,BAZ2A,LIMA1,ANK2,HSPA5,KCNH2,KRTCAP2,ODC1,ST3GAL5,YTHDF2,SPOP,SKIL,EIF4ENIF1,PER1,LUC7L3,CSMD3,RUNX1,MAGI1,ZMAT3,USP15,CLDN15,ANKRD17,FAM189B,HES6,BARX2,XPO7,CDC73,DDIT4,MTUS1,MCAM,CACNB2,MYC,BDNF,EIF4A2,WWC1,WDR25,PRDM1,RABAC1,MBNL2,SERF2,TBPL1,CCDC85B,SQLE,TBL1X,BRSK2,TCF12,ID1,SYT17,DLL4,DNM3,CYLD,TRERF1,MYO7A,FOSL2,RADIL,RPAIN,SPG21,JAG1,TMEM184A,NBEA,ETF1,PLEKHA4,HN1,MOSPD1,SOBP,BRD4,KIRREL2,RAB7A,GRHL3,LGALS1,POU2F1,MEF2D,ARL5B,HSD3B7,FGFR1,TJAP1,ZBTB25,VDR,SLC30A3,LMBR1L,ITGA2,HOXA3,PAM,EIF2B3,LAMA5,ATXN7L2,RFX1,ATF7IP,ENOX1,GIGYF2,BMP6,MBNL1,NEBL,ERRFI1,ZNF710,LDLRAD3,PNMA1,AP4S1,GPHN,C19orf43,ARHGEF12,UBE2K,NAPEPLD,CACNB1,BCAS3,SVIL,RBM26,NR2F2,ITGB4,ADK,KIF1B |
| 2.150e-02 | -3.84 | WW | smart domains | SM00456 | 47 | 12 | 9131 | 1249 |
CEP164,PRPF40B,APBB3,SETD2,ARHGAP39,WAC,PQBP1,WWC1,ARHGAP12,MAGI1,ARHGAP27,NEDD4 |
| 2.154e-02 | -3.84 | WENG_POR_TARGETS_GLOBAL_DN | MSigDB lists | WENG_POR_TARGETS_GLOBAL_DN | 23 | 7 | 17758 | 2279 |
RETSAT,EGR1,HSDL2,MGLL,RAB30,HSD17B10,RAD51B |
| 2.154e-02 | -3.84 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | MSigDB lists | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | 23 | 7 | 17758 | 2279 |
EXOSC2,EXOSC4,ASNS,ATF4,PARN,DDIT3,HERPUD1 |
| 2.154e-02 | -3.84 | KEGG_MISMATCH_REPAIR | MSigDB lists | KEGG_MISMATCH_REPAIR | 23 | 7 | 17758 | 2279 |
EXO1,RFC4,SSBP1,MLH1,RFC3,MSH3,RPA1 |
| 2.154e-02 | -3.84 | chr6p24 | MSigDB lists | chr6p24 | 23 | 7 | 17758 | 2279 |
PAK1IP1,SYCP2L,RIOK1,GCNT2,DSP,TMEM14C,BMP6 |
| 2.154e-02 | -3.84 | S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY | 23 | 7 | 17758 | 2279 |
METTL1,NSD1,SUV39H2,RNMT,PEMT,EHMT1,PCMT1 |
| 2.154e-02 | -3.84 | OSADA_ASCL1_TARGETS_DN | MSigDB lists | OSADA_ASCL1_TARGETS_DN | 23 | 7 | 17758 | 2279 |
CYP24A1,SEMA3C,AHNAK,CD44,CRIM1,FGFR1,DKK1 |
| 2.154e-02 | -3.84 | CAIRO_PML_TARGETS_BOUND_BY_MYC_UP | MSigDB lists | CAIRO_PML_TARGETS_BOUND_BY_MYC_UP | 23 | 7 | 17758 | 2279 |
CAD,ID2,POLR3D,EIF2A,DDX18,ODC1,CDK4 |
| 2.155e-02 | -3.84 | DNA polymerase binding | molecular function | GO:0070182 | 9 | 4 | 16491 | 2164 |
SMARCA4,ACD,LONP1,FANCD2 |
| 2.155e-02 | -3.84 | DNA replication origin binding | molecular function | GO:0003688 | 9 | 4 | 16491 | 2164 |
MCM10,MCM2,MCM5,ORC5 |
| 2.169e-02 | -3.83 | SART1 (squamous cell carcinoma antigen recognized by T-cells 1) | protein interactions | 9092 | 100 | 22 | 16036 | 2270 |
SART1,SNU13,CUL7,PRPF31,TFIP11,SIRT7,HSPA5,SF3A3,TIMM10,NOP58,UBL5,PABPC4,SUB1,SNW1,HNRNPR,LUC7L3,RNF2,PRPF4,SRRM2,PABPC1,SF3A1,PRPF19 |
| 2.172e-02 | -3.83 | regulation of DNA metabolic process | biological process | GO:0051052 | 310 | 53 | 16441 | 2138 |
HMGA2,DNAJC2,ESCO1,CUL4A,ANKRD17,NPAS2,ATRX,SUPT6H,PID1,MLH1,BMP6,UBR5,KDM1A,TOM1L1,TERF2IP,SLX4,BRE,SHC1,ACD,TMEM161A,YLPM1,APLF,NVL,MYC,WIZ,PRMT5,SPIDR,OGG1,CTC1,TERF2,APEX1,SIRT6,PPARG,SMARCAD1,EYA3,BRCA1,MEN1,DKC1,ZNF91,ZRANB3,STOML2,KPNA1,BRCA2,EHMT2,RAD18,CDK9,KLF4,MSH3,H2AFX,APAF1,BMP4,BRCC3,PKIB |
| 2.174e-02 | -3.83 | TOPBP1 (topoisomerase (DNA) II binding protein 1) | protein interactions | 11073 | 56 | 14 | 16036 | 2270 |
ZBTB17,ABL1,SLX4,ACTG1,HSPA5,ATM,SMARCA4,ATRIP,DTD1,BRCA1,UBR5,RMI1,RPA1,CLK2 |
| 2.174e-02 | -3.83 | ECHS1 (enoyl-CoA hydratase, short chain, 1, mitochondrial) | protein interactions | 1892 | 56 | 14 | 16036 | 2270 |
TPD52L2,CAMK2D,RAP1A,CUL7,GINS3,ITPA,UCHL5,HERC1,SUMO3,RAP1GDS1,CNDP2,AHCYL1,VCL,USP15 |
| 2.174e-02 | -3.83 | CIRBP (cold inducible RNA binding protein) | protein interactions | 1153 | 56 | 14 | 16036 | 2270 |
FN1,NARS,LSM14A,KHDRBS1,COPS5,CUL2,ATXN1,CSNK2A1,RTN4,RNF2,POLR1C,BMI1,PRKAR2A,TMPO |
| 2.177e-02 | -3.83 | response to monoamine | biological process | GO:0071867 | 33 | 9 | 16441 | 2138 |
GNG2,ABL1,BDNF,ID1,EGR1,PDE4B,RYR2,SIRT2,SNCA |
| 2.177e-02 | -3.83 | oocyte development | biological process | GO:0048599 | 33 | 9 | 16441 | 2138 |
BRCA2,KMT2D,ATM,KIAA0196,PABPC1L,DMRT1,FOXO3,PDE3A,TRIP13 |
| 2.177e-02 | -3.83 | regulation of DNA-dependent DNA replication | biological process | GO:0090329 | 33 | 9 | 16441 | 2138 |
BRCA2,ATRX,WIZ,PID1,BMP4,BMP6,TERF2,STOML2,ZRANB3 |
| 2.178e-02 | -3.83 | nuclear chromosome, telomeric region | cellular component | GO:0000784 | 80 | 17 | 17570 | 2233 |
HMBOX1,MCM6,SIRT6,NAT10,HIST1H4J,MCM2,TNKS1BP1,CDC73,RPA1,TERF2IP,SLX4,ACD,TP53BP1,MCM5,ORC5,CTC1,TERF2 |
| 2.181e-02 | -3.83 | HALLMARK_ESTROGEN_RESPONSE_EARLY | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_EARLY | 200 | 36 | 17758 | 2279 |
NCOR2,ABCA3,CELSR1,SLC2A1,MED13L,ISG20L2,BHLHE40,SLC1A1,FLNB,HR,PMAIP1,MYC,STC2,MED24,GREB1,RAPGEFL1,CD44,NRIP1,MYB,FDFT1,THSD4,WWC1,FOXC1,MYBBP1A,RBBP8,KDM4B,KLF4,HSPB8,SNX24,SVIL,SLC16A1,FKBP5,SCARB1,DHCR7,BAG1,MAPT |
| 2.182e-02 | -3.82 | DELYS_THYROID_CANCER_UP | MSigDB lists | DELYS_THYROID_CANCER_UP | 438 | 71 | 17758 | 2279 |
TNFRSF21,MFGE8,C16orf45,PTPRG,STAM,IGSF1,PLXNB1,PCDH7,ECM1,MMP7,S100A10,PMAIP1,MET,TRIM14,MALL,COL5A2,UPP1,LGALS1,SEMA3F,ENC1,SOX4,DSP,ODC1,ST3GAL5,SH3GL1,WARS,PLIN2,RBBP8,SYNGR2,ARNTL,ITGA2,TNFRSF1A,AHNAK2,MPV17,H2AFX,DPP4,ABCC3,RUNX1,ANXA2,SPOCK2,HMGA2,FN1,CA11,PRSS3,PRAF2,IGF2BP2,EVPL,TRIM22,BHLHE40,PHLDA2,MTUS1,SCN1B,ATIC,MFAP2,CD44,NRIP1,SAMD4A,NT5E,KCNQ3,TSTA3,PRDM1,NCDN,ANXA1,BICD1,PXDN,PDLIM1,DSC2,VCAN,ADK,DHCR7,GALE |
| 2.191e-02 | -3.82 | mitochondrial intermembrane space | cellular component | GO:0005758 | 74 | 16 | 17570 | 2233 |
TIMM8B,AK2,CPOX,NLN,CHCHD10,OPA1,TIMM10,CIAPIN1,STOML2,CAT,TRAP1,TRIAP1,SHMT2,NDUFS5,UQCC2,HTRA2 |
| 2.191e-02 | -3.82 | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | MSigDB lists | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | 50 | 12 | 17758 | 2279 |
EXOSC2,MCM6,MCM5,MYC,H2AFX,SDCBP2,TIMELESS,NFRKB,MCM2,CHAF1A,MYB,MTHFD1 |
| 2.192e-02 | -3.82 | FN1 (fibronectin 1) | protein interactions | 2335 | 758 | 127 | 16036 | 2270 |
SRM,NDUFA5,PRDX6,ACTG1,DDX18,ACTR3,OLA1,NAT10,MYH9,RSL1D1,CSNK2A1,PPIL1,TUBB6,AARS,PELP1,HSPA1A,HNRNPA3,PABPC4,FLNB,DECR1,IDI1,RPS16,PPID,UBAP2L,SSBP1,RAN,HRG,VCL,YARS,PRPF19,FLNC,DBN1,RFC4,SNU13,SLC3A2,NARS,RAB7A,HSPA5,LGALS1,PCMT1,PSMG1,VIM,MCM2,RAB10,CLNS1A,YTHDF2,ARPC3,SKIL,DDX3X,DDAH2,AHNAK,HNRNPR,G6PD,ACP1,PRPF4,FUS,ANXA2,MDN1,USP15,MCM6,SIRT7,HSD17B10,SF3A3,IGF2BP2,VARS,APRT,PHGDH,RPS6KA5,PDCD5,MBNL1,BZW2,IGF2BP3,SUB1,GART,MCM5,MYC,SEC24C,ANP32B,IGF2BP1,FBL,PRMT5,CD44,TOMM34,PABPC1,PPA1,HNRNPM,SLC25A1,FDFT1,NT5E,PXN,LSM12,XPO5,RAP1B,LDHA,RNH1,MARS,IMPDH2,HIST1H4J,SUPT5H,EIF5B,NOP58,ABCF1,TARS,UBC,HSPA1B,RPA1,ANXA1,DYNC1H1,ATXN7,TRIB3,EPRS,KIDINS220,SYNCRIP,RPL28,FSCN1,TRAP1,SNAP23,HNRNPH3,SET,EIF2S1,PGAM5,POLR1C,NAPA,PDLIM5,SRP14,IPO4,GALE |
| 2.195e-02 | -3.82 | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN | 110 | 22 | 17758 | 2279 |
SLC12A7,EVL,DDX18,TSPYL4,CCDC53,OLA1,ATG12,TMEM123,IMPDH2,PITPNB,EIF5B,FAM8A1,PCYOX1L,SLC7A1,UBAP2,SYNCRIP,ATIC,LUC7L3,PPP3CC,RBM26,TTC3,SNAPC5 |
| 2.196e-02 | -3.82 | - | gene3d domains | 1.20.140.20 | 5 | 3 | 9988 | 1398 |
BCKDK,PDK1,PDK4 |
| 2.196e-02 | -3.82 | - | gene3d domains | 3.30.1220.10 | 5 | 3 | 9988 | 1398 |
CBWD1,CBWD6,CBWD5 |
| 2.198e-02 | -3.82 | MULLIGHAN_NPM1_SIGNATURE_3_UP | MSigDB lists | MULLIGHAN_NPM1_SIGNATURE_3_UP | 321 | 54 | 17758 | 2279 |
AK2,RWDD1,XPC,ATRX,PLOD1,IGF2BP2,ATF7IP,NUP43,RSRC1,SLC39A1,PDE3A,DST,PI4KB,TANK,PDS5B,PAK1IP1,EXOSC4,CELF1,CEP135,ITGAX,ZMYM2,CNOT4,PRPS1,PKNOX1,TMPO,TOP1,SRPK2,VOPP1,FADS1,FAM127A,ZMYM5,ZBED4,TOP3A,SMARCD3,APTX,LAMA2,SON,MBNL2,UBE2K,ARIH2,SH3GL1,MLLT10,CAT,ETFDH,TMCO1,INSIG1,HNRNPH3,TIMM17A,MSH3,HOXA3,PTPN4,ATM,PPP3CC,PDLIM5 |
| 2.201e-02 | -3.82 | ILK (integrin linked kinase) | protein interactions | 3611 | 206 | 40 | 16036 | 2270 |
FN1,SLC2A1,CCDC47,TUBB6,SSR4,CAD,SHC1,UBAP2L,SHMT2,SSBP1,GEMIN4,RAN,IGF2BP1,SRRM2,LPCAT1,LONP1,AUP1,CARM1,HNRNPM,SLC25A1,TIMM50,PXN,AKAP8L,PPAT,ABCF2,FERMT2,MARS,CAV1,RHOT2,TMSB4X,DDX3X,ADNP,DNAJA3,COPS5,FAT1,SLC16A1,FKBP5,HEATR1,ITGB4,PDLIM5 |
| 2.203e-02 | -3.82 | regulation of neurogenesis | biological process | GO:0050767 | 620 | 98 | 16441 | 2138 |
TCF12,DNM3,DLL4,SYT17,CUL7,ID1,NF1,PAFAH1B1,TNFRSF21,C16orf45,NREP,PBX1,SIRT2,RAC3,SEMA6A,LPAR3,PLXNB1,SKI,CHD7,ABL2,KCTD11,RRN3,RAP1A,JAG1,ZFHX3,XRCC2,NCKIPSD,ZEB1,TTC3,CARM1,PRPF19,DBN1,WDR36,PPARG,CUX1,LGALS1,PREX1,ATXN1,SEMA3F,VIM,CAV1,ENC1,FGFR1,SKIL,EIF4ENIF1,ADNP,ARNTL,PQBP1,SEMA3C,DLX2,NRP1,BEND6,MAPT,MEF2C,TNIK,SSH2,BRAF,FN1,CAMK1,TCF3,ID2,RTN4,SEMA3E,GDPD5,BMP6,NEDD4,ABL1,PRKCH,CHN1,SNW1,ASAP1,SCN1B,UNC13A,NDRG4,SEMA3D,TENM3,NLGN3,FBXO31,PRMT5,BDNF,IFRD1,SYNGAP1,FZD3,RAP1GAP2,SMARCD3,LIG4,SNAP25,PTK2,SYT1,NEU1,TCF7L2,SPAG9,KIDINS220,HIF1A,SPEN,BMP4,PDLIM5,ZSWIM6 |
| 2.203e-02 | -3.82 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | 187 | 34 | 17758 | 2279 |
SERINC5,SEC24D,ST6GAL1,OSBPL9,WDR26,RSF1,AP1B1,PIP4K2A,PITPNM1,FKBP1A,RAP1A,CAMTA2,CAMKK2,RREB1,SETD1B,IFNGR2,MYO10,EXOC6B,FOXN3,JMJD1C,ARHGEF10,AKAP12,PRDM1,IL6R,ERC1,ASCC3,LSM14A,CHD3,MKL2,GALNT10,TBL1X,ZMAT3,XPO6,TESC |
| 2.203e-02 | -3.82 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_DN | 187 | 34 | 17758 | 2279 |
SRM,ADAM19,SCAMP3,BTBD2,WDR13,SLK,SLC2A1,REEP5,UBR5,PABPC4,ATXN7L1,AMPD3,PRKD3,RPS16,RASSF3,NDRG4,TBC1D8,RDH10,RAPGEF4,ARHGAP39,PRDM1,POLR2A,SMPDL3B,TPK1,ARPC3,ETFDH,KLHL22,EIF4ENIF1,TASP1,GLG1,ADAM9,TRAF3,HEATR1,MED20 |
| 2.203e-02 | -3.82 | GSE27786_BCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_BCELL_VS_ERYTHROBLAST_UP | 187 | 34 | 17758 | 2279 |
IMMP2L,C10orf2,PRKAB2,VPS45,SF3A3,GYG1,OPA1,ABHD6,UBTD2,NOP56,PTPN2,MLX,ENTPD5,ACD,CFDP1,LTN1,GMDS,SIK3,FAM172A,PDK1,NOL8,MEF2D,ATP8B2,KLF6,RBM28,DHX57,PEX1,YIF1A,PDLIM1,CHD3,ALKBH1,ZNF32,NCOR1,POLR1C |
| 2.203e-02 | -3.82 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | 187 | 34 | 17758 | 2279 |
KLHL24,CTU2,MYCBP2,SSH2,FAM208B,MED13L,GAS6,RLF,PAIP2,RIOK2,SKI,FAM50A,PRKD3,AMPD3,USPL1,TRMU,CELF1,CCDC88C,PKNOX1,RBCK1,AKAP8L,KDM5B,PDK1,WLS,MEF2D,IL6R,BTBD11,SH3GL1,ZZEF1,TNFRSF1A,GLG1,RNF130,YEATS2,STK4 |
| 2.203e-02 | -3.82 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | 187 | 34 | 17758 | 2279 |
WDR74,UBXN1,ZFP36L1,BHLHE40,TGFBR2,CUTC,GIT2,PIP4K2A,RNF141,C6orf48,NISCH,CORO1A,POLR1E,TRIM14,PTPRK,USE1,HMBOX1,CHD9,RBCK1,KDM5B,SKAP2,JMJD1C,DLST,C8orf33,STK10,MSRA,ZNF266,ADNP,SYNGR2,NCOR1,MDN1,GALNT10,IFITM2,USP11 |
| 2.203e-02 | -3.82 | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | 187 | 34 | 17758 | 2279 |
TRIO,MYH9,HLTF,CCNL2,GYG1,C11orf54,FOXO3,KCTD11,ZNF358,XRCC2,LPCAT1,CNOT4,RPL22L1,FBXW4,SETD1B,IL11RA,USP49,POLK,ALDH1L2,TMEM126A,ZMYM5,ZNF512B,LGALS1,COL4A3BP,FERMT2,ARHGAP32,LENG8,ENC1,YTHDF2,BAZ1A,CHD3,COPS5,TNFRSF1A,NCBP2 |
| 2.203e-02 | -3.82 | GSE17721_LPS_VS_POLYIC_16H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDM_UP | 187 | 34 | 17758 | 2279 |
DCTN3,UROD,PDE4B,NUP43,RNF141,MLX,ZDHHC6,UPF2,PRADC1,FBL,PRMT5,COQ3,ETV1,PRPS1,POLA1,EIF3J,WDHD1,LSG1,TMEM206,ECH1,PWP1,CDC16,RAD18,ACOX1,METTL6,FDPS,GLG1,TRMT2A,BPNT1,COPS6,NFKBIB,IGBP1,BLMH,IPO4 |
| 2.204e-02 | -3.81 | endoribonuclease activity | molecular function | GO:0004521 | 49 | 12 | 16491 | 2164 |
RPP30,POP1,EXO1,DROSHA,APEX1,AGO2,TSN,POP5,CPSF3,RNASEH2B,TSEN2,EDC3 |
| 2.204e-02 | -3.81 | glycerolipid metabolic process | biological process | GO:0046486 | 344 | 58 | 16441 | 2138 |
SERINC5,PIGM,INSIG2,PIGN,PAFAH1B1,LPCAT2,GPAT3,PIGH,TNXB,PIK3R4,PLA2G12A,DPM3,LPCAT3,IP6K2,ABHD6,SYNJ1,LCLAT1,INPP1,PIP4K2A,LPIN1,PI4KB,LPIN2,ACOT11,PIGG,SYNJ2,CPNE7,PNPLA3,SLC27A5,MGLL,LPCAT1,PRKACB,HSD17B12,SLC25A1,ACSL5,FGF2,ELOVL6,PI4KAP2,AGPAT4,GPCPD1,PITPNB,CAV1,CPT1A,PLCB1,PIK3CB,VAC14,DAGLA,TAMM41,CAT,ALG5,SERINC1,INSIG1,PEMT,ABHD3,ATM,GPAM,BPNT1,MTMR1,SMG1 |
| 2.207e-02 | -3.81 | V$IPF1_Q4 | MSigDB lists | V$IPF1_Q4 | 240 | 42 | 17758 | 2279 |
TCF12,ZHX3,RHOBTB1,PPP2R2A,RNF24,NECAP1,ATF7IP,IP6K2,FOXO3,UBR5,MBNL1,ZNF827,ENTPD5,SREBF2,SAMD11,PAK1IP1,MAML3,SOBP,BDNF,DPF3,MPP6,SESN2,FOXN3,ELOVL6,PPP1R21,TCEB3,CUX1,PRDM1,SOX4,C1orf122,GNAI1,SLC39A14,SYNCRIP,PMEPA1,ARID3B,PPP3CC,BMP4,NRP1,NR2F2,BMI1,PDLIM5,MEF2C |
| 2.214e-02 | -3.81 | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN | 174 | 32 | 17758 | 2279 |
SEC24D,SMAD7,MAP2K3,EDC3,SRPRB,ATXN7L1,FARSA,RAP1A,PHF5A,GATC,WAC,ARHGAP1,ALDH18A1,MGLL,AKAP11,CNTNAP3B,TRIM14,SF3A1,DDX28,EIF3J,NOL8,ATP6V0A1,MED16,ACOXL,MLLT10,GLS,PAF1,SUPT4H1,HYAL3,CCNT1,SIX5,SLC4A7 |
| 2.214e-02 | -3.81 | V$MYC_Q2 | MSigDB lists | V$MYC_Q2 | 174 | 32 | 17758 | 2279 |
CGN,AK2,UBXN1,NAT10,ATF7IP,TGFB2,RLF,TIMM10,PABPC4,CNST,ACAP3,GTF2H1,SHMT2,ALDH18A1,SERBP1,NUDC,RTN4RL2,NRAS,LDHA,KRTCAP2,UBR4,POLR3A,BATF3,HNRNPH3,SLC16A1,PFDN2,MACROD1,ADK,USP15,NIT1,ATXN7L2,SLC43A1 |
| 2.219e-02 | -3.81 | regulation of synaptic vesicle exocytosis | biological process | GO:2000300 | 18 | 6 | 16441 | 2138 |
BRAF,RAP1A,SEPT5,NAPA,STX1A,RAP1B |
| 2.219e-02 | -3.81 | regulation of hormone biosynthetic process | biological process | GO:0046885 | 18 | 6 | 16441 | 2138 |
TRERF1,HIF1A,BMP6,KDM1A,STC2,PDE8B |
| 2.219e-02 | -3.81 | positive regulation of cardiac muscle cell proliferation | biological process | GO:0060045 | 18 | 6 | 16441 | 2138 |
FGF9,RBPJ,GATA6,FGF2,FGFR1,MEF2C |
| 2.224e-02 | -3.81 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | 294 | 50 | 17758 | 2279 |
ZNF292,TNIK,CYLD,LUZP1,TFIP11,PDE4B,NFX1,ID2,RTN4,WDR37,TRIM22,TGFBR2,REEP5,GIT2,MCM9,SFI1,MAN1A1,MTUS1,CHN1,IDI1,KDM2A,BCAS2,PMAIP1,RABGAP1L,CTR9,RDX,PRF1,KLRD1,FAM98A,BAZ2A,PTPRM,RAP1GAP2,ARHGEF10,ATG12,ATXN1,PHACTR2,PRDM1,ENC1,SERINC1,HNRNPH3,ARL6IP5,CUL2,CEBPZ,ARNTL,PAM,ATM,PPP3CC,GALNT10,ANXA2,N4BP2L2 |
| 2.230e-02 | -3.80 | fourth_ventricle | COSMIC cancer mutations | fourth_ventricle | 39 | 10 | 17775 | 2278 |
BRAF,NRAS,CLCN6,RNF130,MEN1,MET,KIAA1549,FGFR1,SMARCB1,GNAI1 |
| 2.231e-02 | -3.80 | parathyroid-adenoma | COSMIC cancer mutations | parathyroid-adenoma | 194 | 35 | 17775 | 2278 |
FEZ2,BRAF,PCNT,TNFRSF21,GPR143,MAPK8IP3,MKS1,SLC25A12,KIF5C,CDC73,FLNB,PDE3A,ZNF354A,TTC3,DYNC2H1,CCDC88C,IPO11,LYST,HNRNPM,NT5E,TBC1D8,ZCCHC14,GPM6A,NRAS,MANBAL,NLN,FAM126B,MEN1,KCNH2,EPRS,ATAD5,FAT1,DNAH17,NFRKB,MMP16 |
| 2.233e-02 | -3.80 | Znf_CCCH | interpro domains | IPR000571 | 56 | 13 | 18293 | 2341 |
TOE1,DUS3L,HELZ,ZC3H18,ZFP36L1,RBM26,ZC3H8,MBNL2,CNOT4,ZC3H3,MBNL1,DHX57,ZC3H13 |
| 2.235e-02 | -3.80 | CTBP2 (C-terminal binding protein 2) | protein interactions | 1488 | 89 | 20 | 16036 | 2270 |
NOL4L,ACTG1,RPS29,EHMT1,ZNF512B,PNN,PLCB1,PSMF1,UBC,DYRK1B,BAZ2B,RBBP8,EHMT2,BCAS3,ZEB1,WIZ,RUNX1,NRIP1,SOX6,CASP8AP2 |
| 2.235e-02 | -3.80 | IKZF1 (IKAROS family zinc finger 1) | protein interactions | 10320 | 89 | 20 | 16036 | 2270 |
NCOR2,SYT17,PRKAB2,PSMA1,SMARCA4,C8orf33,ZMAT2,C1orf174,MAD2L2,SNW1,RBBP8,IKZF5,ALKBH3,IKZF4,NEK6,CHD3,AP1M1,ANKRD11,AEN,RWDD2B |
| 2.237e-02 | -3.80 | MOHANKUMAR_TLX1_TARGETS_UP | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_UP | 390 | 64 | 17758 | 2279 |
PTP4A1,SNX27,OSBPL9,PBX1,ISG20L2,HSPA1A,LPIN1,SKI,SPG21,COPS4,TTC3,CARM1,GDAP1,TFPI,MARCKSL1,MAT2A,ADNP,TIMM17A,G6PD,E2F4,DNAJA3,MKL2,LARGE,HSPB8,H2AFX,CLU,NOLC1,TSPAN5,SEPHS2,BCKDK,CDC42EP2,TTC27,SEC24D,ALG8,SMG7,MED13L,CCDC47,BHLHE40,PIP4K2A,BZW2,CHN1,GTF2H1,SELT,CELF1,PNPLA3,HNRNPM,MTHFD1,GINS3,LDHA,TBRG4,PALLD,CYB5B,UBE2K,NAALADL2,UBE2E1,PGD,RPA1,HSPA1B,CAT,HELZ,TRAP1,FAT1,GLG1,HMBS |
| 2.240e-02 | -3.80 | TTGTTT_V$FOXO4_01 | MSigDB lists | TTGTTT_V$FOXO4_01 | 1950 | 279 | 17758 | 2279 |
DPH1,TNFRSF21,UBR5,NOS1AP,PCDH7,RNF111,CHD2,CDK6,NRAS,PTPRM,NFIA,MSRB3,ZDHHC14,DENND4A,SLC50A1,PLCXD2,STOML2,SLC7A1,LUC7L3,HSPBAP1,RUNX1,FIP1L1,NRP1,BMI1,ZMAT3,ZNF532,MEF2C,LPP,PRPF38B,EGR1,JUP,CCDC53,ST6GAL1,DLGAP4,RSF1,CLINT1,SLC1A1,CHN1,HR,UBE3A,TSPAN2,SLC7A11,TNPO3,CALN1,AGL,CAV2,SERBP1,ANGPT2,SIK3,BDNF,RREB1,STAG1,RDH10,KIAA0586,RAP1B,PTPN12,IMPDH2,PLCB1,ONECUT2,MBNL2,EHBP1,NCDN,PHF6,SEC31A,IRS1,C6orf141,GTF2A1,EHMT2,NSF,HIF1A,RIOK3,TRERF1,BIRC6,ATP6V1A,NPAS2,ZBTB37,PDK4,OLA1,C1QTNF7,MAB21L3,FOSL2,ZMAT2,IGSF1,PAIP2,CD96,KDM2A,INTS12,PXK,MGLL,SAP30,ZCCHC14,MPP6,SFXN4,NPM3,ATP6V0A1,SATB2,GSTCD,DSP,SERP1,DHX57,MAT2A,VDR,MSX2,CAMKMT,PAM,HOXA3,SLC4A7,RPS6KB1,XRCC4,ANKS1A,RAB30,HMGA2,SSH2,NOSTRIN,ZNF280C,SLC25A12,ID2,AKT1S1,IP6K2,TGFB2,DNAJC22,INPP1,NEDD4,SOX6,NAV3,PFKFB4,FGF9,SLC40A1,ZFYVE1,NXN,APTX,PDE3B,GUF1,ANXA1,NSD1,IREB2,STX18,RNF138,BMP4,IMMP2L,PHF3,NF1,MFGE8,CSNK2A1,RNF43,BCOR,STK33,DST,RTN1,ZNF804A,SRSF2,SLC39A7,ZMYM2,ETV1,TRIM14,VPS13B,SRPK2,LAMA4,FMNL3,SESN2,GPM6A,TXLNG,ARRDC3,MED27,GMFB,ZSCAN2,BSN,EPN2,INSIG1,TOM1L2,GATA6,ARL4A,PER1,DLX2,MAGI1,RNF214,TNRC6A,TTN,FN1,FOXO1,STXBP6,PAX2,ZIC2,XPO7,ARID1B,DDIT4,CCDC112,CTR9,CWF19L2,MSI2,LAMC1,USP49,PPAT,ELOVL6,TLE3,JMJD1C,HOMER2,UTP15,WDR25,ZNFX1,PRDM1,TCF7L2,NR2F1,NAP1L5,GRIK4,BICD1,SPAG9,EXOC4,HMBS,ID1,PAPD4,TNXB,SMARCA4,TBCCD1,PBX1,RNF24,SPATS2,SSBP2,SEMA6A,RRN3,JAG1,CCDC50,CYB5D1,SLC38A2,CORO1A,VCL,GNG5,MAML3,PRPF19,SOBP,EVL,TUBA1A,CPOX,NLN,POU2F1,ATXN1,TOR1AIP2,ENC1,RAB10,RAD54B,SMAD3,IKZF4,LMBR1L,ITGA2,ZNF436,FKBP5,TSPAN5,SMG1,ATXN7L2,KLHL24,UNC13D,MAP3K13,KLC4,CLSTN2,ATF7IP,FOXP1,MAN1A1,STC2,GREB1,TTC17,AMOT,TOP1,MSX1,MON1A,CRIM1,TEAD1,FOXN3,KDM5A,ZNF654,PALLD,NAALADL2,ZBTB8OS,TBX3,EIF2S1,PREPL,NR2F2,POLR1C,ITGB4,ZAK |
| 2.243e-02 | -3.80 | BIDUS_METASTASIS_UP | MSigDB lists | BIDUS_METASTASIS_UP | 207 | 37 | 17758 | 2279 |
PTP4A1,MCM10,NF1,KHDRBS1,DBF4,ZIC2,CCDC47,ANKRD54,RRN3,SRSF2,RABGAP1L,DCTN4,WAC,PNMA1,CCDC57,RFC4,NRAS,KLHL23,RAB7A,WDHD1,EFHC1,DKC1,DSP,ODC1,AGAP1,MLLT10,IFT81,TSR1,ADNP,HNRNPR,HNRNPH3,RNF138,SQLE,NCBP2,PREPL,KIF1B,TMEM33 |
| 2.244e-02 | -3.80 | trunk | COSMIC cancer mutations | trunk | 3691 | 510 | 17775 | 2278 |
ARHGAP26,GGT1,MYCBP2,CGN,CDCP1,THOC5,PLRG1,NAT10,ADAMTS6,SYNJ1,UBR5,PABPC4,PCDH7,PDZD2,SREBF2,ZFHX3,CHD2,FXN,SPAG6,CSGALNACT2,ZNF646,SLC38A6,NRAS,RNMT,PTPRM,EHMT1,EYA3,VSNL1,CUX1,RFX2,WDHD1,AKAP12,SEMA3F,SON,DDX60,SLC50A1,TMEM206,OSBPL1A,AHNAK,BRCA2,TRRAP,SH3RF1,LRRC40,ZNF81,VPS13D,DNAH2,RIOK1,NRP1,SPOCK3,ZNF532,ZMAT3,PTPN14,CADM4,HERC2,EP400,TMEM63C,CELSR1,ANKRD17,ZHX3,FAM189B,TRIO,DLGAP4,OPHN1,PIK3R4,RSF1,CDC73,ABCA7,MTUS1,TECTA,RBM20,C6orf48,UBE3A,PI4KB,DHX37,APLF,USPL1,SCAF1,ASAP1,CACNB2,MYC,MED24,IGF2BP1,GTF3C3,LPCAT1,MAP3K12,FMNL2,MYB,NOM1,RABEPK,GATAD2B,DDX28,COL17A1,RREB1,PRDM16,AOC2,RAPGEF4,TYW1,RDH10,ZNF512B,RYR2,PTPN12,SNAP25,ARID1A,ARRDC4,PLCB1,MTR,ABCF1,ARIH2,DYNC1H1,ASCC3,VPS13C,LRP1B,NME7,PDLIM1,CLASRP,FGFBP1,LEMD3,VCAN,SPEN,ZZEF1,ZNF160,ZCCHC6,CNDP2,IQSEC2,DHCR7,SRP14,COG5,CPT1C,RTTN,SYT17,DNM3,TRPM2,ZNF516,RWDD1,URB2,NECAP1,ISG20L2,GRINA,PTPRG,FLNB,TRIM66,CHD7,PRKD3,CD96,ZNF827,SLX4,ABCA12,FMNL1,CLCN6,NBEA,TTC3,CEP63,MSH4,PEG10,KMT2A,RFC4,GARS,KMT2D,GON4L,NPM3,MTIF2,ARHGEF10,ADAM32,PCNXL2,ATP6V0A1,PNN,GALK2,GSTCD,DSP,FKBP3,DHX57,PDE8B,BAZ1A,ARHGAP21,IQCH,CDC16,ELP2,KDM4B,ASTN2,HIPK2,WDR7,LARGE,HOXA3,IFT140,BRCC3,LAMA5,CEP170,YEATS2,MID1,TRIM36,LRCH1,MORC2,ZNF786,SSH2,BRAF,TTC27,NFX1,RTN4,GDPD5,GIGYF2,POM121,NEDD4,ZNF483,NEBL,ACAP3,UPF2,ERRFI1,SPTAN1,CLK2,FER1L5,TTPAL,FGF9,VPS37A,CLYBL,WDFY3,LSM12,POLK,ZC4H2,FZD3,FAM126B,GUF1,CASC1,ETFDH,KLHL22,TRIB3,RARS,SRCAP,NSD1,NME1-NME2,IREB2,HELZ,HERC1,ACOX1,SRD5A3,RNF138,SVIL,MYOM2,SLC43A1,STK4,CYP24A1,CUL7,ATRX,NF1,GPBP1L1,PTPRA,MFGE8,FANCD2,TRPM6,CSNK2A1,SLC29A1,BCOR,STK33,GIT2,BIRC2,RTN1,ZNF804A,ABL2,DST,ARHGAP18,PHKA1,YLPM1,MARVELD2,ANKRD11,MYH3,TRIML2,RELB,GPATCH1,ZEB1,B3GNTL1,KIAA0922,POLR3B,HCFC2,SLC25A23,OGG1,TRIM14,MPST,SRPK2,PTPRK,VPS13B,DSC3,CHD9,ATF4,SKAP2,ABCC4,MIOS,PPARG,ANK2,TSN,NOL6,KSR2,PSMG1,LAMA2,KMT2C,KCNH2,ODC1,ST3GAL5,PEX1,KIF16B,CHAF1A,DYRK1B,TMEM132B,GEMIN5,EPN2,LSS,TP53BP1,DNAJC1,FAM114A2,TECPR2,CCDC146,CTAGE5,CSMD3,PPP3CC,GALNT10,MAGI1,BEND6,CHMP4C,TNRC6A,AOC3,AK2,STX8,SEC24D,TAF1,CLK1,HSD17B10,SMG7,TRIM15,QSER1,EVPL,XPO7,RLF,ARID1B,DOPEY1,RNF40,KIAA1958,SIPA1L3,ZNF358,CEP290,PDE10A,ATXN2,WDR27,TIMELESS,SYNJ2,PNPLA3,ALDH18A1,ZCCHC7,AKAP11,N4BP2,MTHFD1,RANBP6,XPO5,SETD2,JMJD1C,TBXAS1,WDR25,OBSCN,ZNFX1,PRDM1,CORIN,SUPT5H,ANKRD20A4,AGAP1,ACOXL,DNAH14,TCF7L2,TBC1D2,BICD1,FAM135A,SPAG9,KIAA0355,INTS5,FAT1,DNAH17,SDCCAG8,EXOC4,HK2,PPP1R12B,CASS4,KIAA1328,ARHGAP12,ZFP90,TBL1X,GGT7,TBCK,PDE9A,C7orf26,TCF12,USP7,ASH1L,PCNT,ARID2,CELSR3,NTSR1,TMEM183A,GPR143,SMARCA4,COBLL1,ARSJ,DENND3,TNKS1BP1,UBTD2,DDX60L,DHX35,PLXNB1,ZSCAN5A,CAD,VPS18,METTL16,DUS4L,GRIN2C,RPS6KL1,FGGY,ZDHHC6,CYB5D1,SNTG2,SLC38A2,ANKRD24,ZNF142,MYH15,AKNAD1,MET,ITGAX,C6orf89,IPO11,CTC1,TMEM200A,WDR36,PRAME,PHLDB2,COL5A2,SSFA2,PTBP2,NARS,MANBAL,CPOX,ATXN1,R3HDM1,SLC35F2,ATP8B2,NUP214,UBR4,USP36,BTBD11,SMAD3,ARMC4,RANBP2,RBBP8,ADNP,COPS5,ATG7,ZNF436,FKBP5,NFASC,NFRKB,HEATR1,SMG1,PARD3,SULT1C2,SH2D3A,SUPT6H,DYM,DBF4,CLSTN2,C14orf159,VARS,SEMA3E,FOXP1,RMI1,POGZ,MAN1A1,IQGAP2,IL17RE,SACS,SCN1B,TMEM161A,DSG2,DDX31,POLR1B,CPNE7,AMOT,TOP1,KDM6B,ADAMTSL3,LRRIQ1,FOXN3,KDM5A,ABCF2,TEX14,TOP3A,YIPF3,PALLD,EXOG,NAALADL2,MKX,CTIF,ZNF221,CACNB1,GPC2,DSC2,L3MBTL3,MPP7,AGTPBP1,CUL2,GLG1,BCAS3,MSH3,RBM26,PREPL,ITGB4,GCSH,ARHGAP27 |
| 2.246e-02 | -3.80 | human chr1q22 | chromosome location | human chr1q22 | 50 | 10 | 26250 | 2590 |
PAQR6,ASH1L,GON4L,FDPS,MEX3A,DPM3,SLC25A44,KRTCAP2,SLC50A1,GPATCH4 |
| 2.250e-02 | -3.79 | STRIATED_MUSCLE_DEVELOPMENT | MSigDB lists | STRIATED_MUSCLE_DEVELOPMENT | 39 | 10 | 17758 | 2279 |
TTN,IFRD1,CACNB2,MKL2,TBX3,CACNA1H,SVIL,SIRT2,BMP4,MBNL1 |
| 2.250e-02 | -3.79 | CHUNG_BLISTER_CYTOTOXICITY_DN | MSigDB lists | CHUNG_BLISTER_CYTOTOXICITY_DN | 39 | 10 | 17758 | 2279 |
FKBP1A,SLC40A1,PDLIM1,SNAP23,C12orf76,RAP1GAP2,MED13L,CSTA,VCL,MAML3 |
| 2.250e-02 | -3.79 | KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN | MSigDB lists | KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN | 39 | 10 | 17758 | 2279 |
GLS,BRCA2,S100A10,HK2,PPP2R2A,NT5C,BLMH,TESC,CLNS1A,TMPO |
| 2.250e-02 | -3.79 | GENTILE_UV_RESPONSE_CLUSTER_D8 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D8 | 39 | 10 | 17758 | 2279 |
IRS1,SPRED2,INSIG1,PPID,HNRNPH3,SQLE,NR2F2,MET,TSPAN5,HMGCR |
| 2.254e-02 | -3.79 | negative regulation of chromatin modification | biological process | GO:1903309 | 44 | 11 | 16441 | 2138 |
SUPT6H,KDM5A,SET,ATG7,BCOR,BRCA1,UBR5,KDM1A,SKI,SMARCB1,SNCA |
| 2.257e-02 | -3.79 | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_IV | 56 | 13 | 17775 | 2278 |
BRAF,KMT2D,KPNA3,SUPT6H,IDH3G,ATG7,ATM,SMARCD3,TRAPPC6B,HCFC2,DDX60,KIAA1549,FGFR1 |
| 2.258e-02 | -3.79 | PFKP (phosphofructokinase, platelet) | protein interactions | 5214 | 67 | 16 | 16036 | 2270 |
CUL7,FN1,SIRT7,AGO2,PSMG1,OXSR1,EPRS,SNW1,ACD,COPS5,ARHGAP1,FUS,NMD3,PARD3,TMPO,MTHFD1 |
| 2.258e-02 | -3.79 | CBX4 (chromobox homolog 4) | protein interactions | 8535 | 67 | 16 | 16036 | 2270 |
MYCBP2,PCGF3,KDM5B,SCMH1,CSNK2A1,MGA,RING1,ISG15,SNCA,SKIL,PHC2,HIPK2,RNF2,BMI1,KMT2A,DIS3L2 |
| 2.258e-02 | -3.79 | DNAJA2 (DnaJ (Hsp40) homolog, subfamily A, member 2) | protein interactions | 10294 | 67 | 16 | 16036 | 2270 |
DNAJA4,SMARCAD1,ABCF2,HSPA5,METTL23,HSPA1A,UBC,CAD,SMAD3,SHC1,MYC,COPS5,RNF2,RPS6KB2,NUDC,TERF2 |
| 2.262e-02 | -3.79 | regulation of autophagy | biological process | GO:0010506 | 185 | 34 | 16441 | 2138 |
WDR75,FEZ2,FOXO1,SIRT2,TRIM22,SOGA1,PIP4K2A,AMBRA1,ABL2,ABL1,TMEM150C,SREBF2,WAC,MET,LRSAM1,HTRA2,KAT8,ZBTB17,TRIM13,RB1CC1,WDFY3,RAB7A,USP10,SUPT5H,PIK3CB,USP36,POLR3A,ZC3H12A,RPL28,HIF1A,HERC1,ATG7,RRAGA,MAPT |
| 2.266e-02 | -3.79 | modulation by virus of host morphology or physiology | biological process | GO:0019048 | 61 | 14 | 16441 | 2138 |
SMAD3,RANBP2,KPNA1,KPNA3,NUP133,HIPK2,ATG7,RRAGA,VAPB,NUP43,NUP160,NUP214,SEH1L,POM121 |
| 2.266e-02 | -3.79 | ZNF606 (zinc finger protein 606) | protein interactions | 80095 | 5 | 3 | 16036 | 2270 |
THOC5,UBN1,CDK12 |
| 2.266e-02 | -3.79 | Mical3 (microtubule associated monooxygenase, calponin and LIM domain containing 3) | protein interactions | 194401 | 5 | 3 | 16036 | 2270 |
GNL1,ALDH18A1,MICAL3 |
| 2.266e-02 | -3.79 | HELB (helicase (DNA) B) | protein interactions | 92797 | 5 | 3 | 16036 | 2270 |
PMS1,POLA1,RPA1 |
| 2.266e-02 | -3.79 | NPM2 (nucleophosmin/nucleoplasmin 2) | protein interactions | 10361 | 5 | 3 | 16036 | 2270 |
NPM3,SRPK2,SDCBP2 |
| 2.266e-02 | -3.79 | CRYZL1 (crystallin zeta like 1) | protein interactions | 9946 | 5 | 3 | 16036 | 2270 |
SHMT2,BRCA1,PPP1R21 |
| 2.266e-02 | -3.79 | DCLRE1A (DNA cross-link repair 1A) | protein interactions | 9937 | 5 | 3 | 16036 | 2270 |
ATM,TP53BP1,UBC |
| 2.266e-02 | -3.79 | CACNA1H (calcium channel, voltage-dependent, T type, alpha 1H subunit) | protein interactions | 8912 | 5 | 3 | 16036 | 2270 |
GNG2,KDM5B,KCNMA1 |
| 2.266e-02 | -3.79 | ZFP28 (ZFP28 zinc finger protein) | protein interactions | 140612 | 5 | 3 | 16036 | 2270 |
HMOX2,C8orf33,KDM1A |
| 2.266e-02 | -3.79 | LDOC1L (leucine zipper, down-regulated in cancer 1-like) | protein interactions | 84247 | 5 | 3 | 16036 | 2270 |
DDIT3,STX18,TERF2 |
| 2.266e-02 | -3.79 | DCLRE1B (DNA cross-link repair 1B) | protein interactions | 64858 | 5 | 3 | 16036 | 2270 |
SLX4,TERF2,FANCD2 |
| 2.266e-02 | -3.79 | FBLN7 (fibulin 7) | protein interactions | 129804 | 5 | 3 | 16036 | 2270 |
EDEM2,HSPA5,CLNS1A |
| 2.266e-02 | -3.79 | COX20 (COX20 cytochrome c oxidase assembly factor) | protein interactions | 116228 | 5 | 3 | 16036 | 2270 |
CBWD1,UQCC2,UQCC1 |
| 2.266e-02 | -3.79 | Haus8 (4HAUS augmin-like complex, subunit 8) | protein interactions | 76478 | 5 | 3 | 16036 | 2270 |
POP1,HAUS6,WDR18 |
| 2.266e-02 | -3.79 | PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1-like 1) | protein interactions | 221823 | 5 | 3 | 16036 | 2270 |
COPS5,PRPS1,TERF2 |
| 2.266e-02 | -3.79 | POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220kDa) | protein interactions | 282312 | 5 | 3 | 16036 | 2270 |
BRCA1,CCNT1,CDK9 |
| 2.266e-02 | -3.79 | NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor) | protein interactions | 26012 | 5 | 3 | 16036 | 2270 |
RAN,SUPT5H,POLR2A |
| 2.266e-02 | -3.79 | TEX9 (testis expressed 9) | protein interactions | 374618 | 5 | 3 | 16036 | 2270 |
CCDC112,NOL4L,KDM1A |
| 2.266e-02 | -3.79 | MYOM2 (myomesin 2) | protein interactions | 9172 | 5 | 3 | 16036 | 2270 |
MYH9,TTN,TERF2 |
| 2.266e-02 | -3.79 | LGALSL (lectin, galactoside-binding-like) | protein interactions | 29094 | 5 | 3 | 16036 | 2270 |
TERF2IP,ACD,MAD1L1 |
| 2.266e-02 | -3.79 | TSKS (testis-specific serine kinase substrate) | protein interactions | 60385 | 5 | 3 | 16036 | 2270 |
SF3A3,USP10,SF3A1 |
| 2.266e-02 | -3.79 | HMGB3P1 (high mobility group box 3 pseudogene 1) | protein interactions | 128872 | 5 | 3 | 16036 | 2270 |
BANP,COPS5,CHMP4C |
| 2.266e-02 | -3.79 | BCKDHA (branched chain keto acid dehydrogenase E1, alpha polypeptide) | protein interactions | 593 | 5 | 3 | 16036 | 2270 |
POLB,BCKDK,PPM1K |
| 2.266e-02 | -3.79 | PAPOLB (poly(A) polymerase beta) | protein interactions | 56903 | 5 | 3 | 16036 | 2270 |
MTHFD1L,TTC38,PABPC1 |
| 2.266e-02 | -3.79 | WNT9B (wingless-type MMTV integration site family, member 9B) | protein interactions | 7484 | 5 | 3 | 16036 | 2270 |
ZZEF1,HSPA5,HECTD3 |
| 2.266e-02 | -3.79 | ATP4B (ATPase, H+/K+ exchanging, beta polypeptide) | protein interactions | 496 | 5 | 3 | 16036 | 2270 |
CCNDBP1,STX1A,AGO3 |
| 2.266e-02 | -3.79 | TDRD1 (tudor domain containing 1) | protein interactions | 56165 | 5 | 3 | 16036 | 2270 |
RNF2,TFCP2,BMI1 |
| 2.266e-02 | -3.79 | SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1) | protein interactions | 79987 | 5 | 3 | 16036 | 2270 |
SMAD3,SKIL,ATF7IP |
| 2.266e-02 | -3.79 | CPSF4L (cleavage and polyadenylation specific factor 4-like) | protein interactions | 642843 | 5 | 3 | 16036 | 2270 |
BANP,WDR33,FIP1L1 |
| 2.266e-02 | -3.79 | MSC (musculin) | protein interactions | 9242 | 5 | 3 | 16036 | 2270 |
ID2,TCF12,TCF3 |
| 2.266e-02 | -3.79 | PXDNL (peroxidasin like) | protein interactions | 137902 | 5 | 3 | 16036 | 2270 |
CSPP1,CARM1,SPTAN1 |
| 2.267e-02 | -3.79 | PLRG1 (pleiotropic regulator 1) | protein interactions | 5356 | 51 | 13 | 16036 | 2270 |
SNW1,KPNA1,CTNNBL1,BCAS2,UCHL5,USP42,SF3A3,PRPF4,BMI1,PABPC1,PABPC4,PRPF19,SF3A1 |
| 2.267e-02 | -3.79 | UGP2 (UDP-glucose pyrophosphorylase 2) | protein interactions | 7360 | 51 | 13 | 16036 | 2270 |
GART,CC2D1B,SET,SNX24,PTPN12,HIRIP3,TROVE2,TARS,CARM1,ARIH2,ISG15,USP15,NUDC |
| 2.267e-02 | -3.79 | EIF3L (eukaryotic translation initiation factor 3, subunit L) | protein interactions | 51386 | 51 | 13 | 16036 | 2270 |
DDX3X,RRN3,RPS16,EIF3C,FN1,SIRT7,EIF4A2,H2AFX,RNF2,POLR1B,AGO3,EIF3H,RIOK2 |
| 2.267e-02 | -3.79 | STX6 (syntaxin 6) | protein interactions | 10228 | 51 | 13 | 16036 | 2270 |
VPS18,STX8,NSF,SNAP23,STX18,CUX1,VPS45,VTI1A,VPS52,GTF3C3,NAPA,EEA1,VPS53 |
| 2.268e-02 | -3.79 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway | REACTOME pathways | R-HSA-110373 | 22 | 7 | 8202 | 1117 |
RFC4,POLB,RFC3,APEX1,POLE2,PARP2,RPA1 |
| 2.268e-02 | -3.79 | cleavage furrow | cellular component | GO:0032154 | 45 | 11 | 17570 | 2233 |
DCTN3,RAB11FIP4,LIMA1,STAMBP,WDR73,MYH9,SVIL,RDX,MEN1,PITPNM1,SPIRE1 |
| 2.268e-02 | -3.79 | cell surface furrow | cellular component | GO:0097610 | 45 | 11 | 17570 | 2233 |
DCTN3,RAB11FIP4,LIMA1,STAMBP,WDR73,MYH9,SVIL,RDX,MEN1,PITPNM1,SPIRE1 |
| 2.269e-02 | -3.79 | TCATCTC,MIR-143 | MSigDB lists | TCATCTC,MIR-143 | 142 | 27 | 17758 | 2279 |
MSI2,SOBP,DTNB,SSH2,COL5A2,SIGMAR1,ATP6V1A,ARL15,RAB7A,NECAP1,AKAP13,BRCA1,GIGYF2,SCAF8,PHF6,BSN,PRKCE,BICD1,SLC38A2,PTPN4,VAPB,HMBS,AHCYL1,SH3PXD2A,CNOT4,MIPOL1,PRPF19 |
| 2.271e-02 | -3.79 | histone mRNA metabolic process | biological process | GO:0008334 | 28 | 8 | 16441 | 2138 |
PAPD4,ERI1,ZCCHC6,ATM,NCBP2,EXOSC4,CPSF3,LSM10 |
| 2.271e-02 | -3.79 | folic acid-containing compound metabolic process | biological process | GO:0006760 | 28 | 8 | 16441 | 2138 |
MTHFD2,GART,ATIC,ALDH1L2,SHMT2,MTHFD1L,MTHFD2L,MTHFD1 |
| 2.271e-02 | -3.79 | tetrapyrrole biosynthetic process | biological process | GO:0033014 | 28 | 8 | 16441 | 2138 |
ALAD,CPOX,UROD,HMBS,COX10,FXN,TMEM14C,MMAA |
| 2.271e-02 | -3.79 | cellular response to catecholamine stimulus | biological process | GO:0071870 | 28 | 8 | 16441 | 2138 |
GNG2,ABL1,BDNF,ID1,PDE4B,RYR2,SIRT2,SNCA |
| 2.271e-02 | -3.79 | response to arsenic-containing substance | biological process | GO:0046685 | 28 | 8 | 16441 | 2138 |
DDX3X,ATF4,ALAD,GSTO2,CPOX,UROD,ABCC2,HMBS |
| 2.273e-02 | -3.78 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | 194 | 35 | 17758 | 2279 |
SRM,HERC2,USP7,MCM10,RWDD1,ATP6V1A,OSBPL9,MAP1S,CSNK1A1,AARS,DENR,NUBPL,CAD,NDUFV1,IPP,ANP32B,SERBP1,HNRNPM,TERF2,TOP1,WDR61,POLA1,TMEM126B,EIF3J,ATOX1,KIF15,COTL1,SON,STOML2,RPA1,HPRT1,SERF2,POLR3E,ABHD3,ANXA2 |
| 2.273e-02 | -3.78 | GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDM_DN | 194 | 35 | 17758 | 2279 |
WDR75,DNAJC2,PIGM,PRDX6,RBM19,SCAF8,PABPC4,TMCO6,RIOK2,SHC1,PMPCA,ME1,MET,LYRM5,LPCAT1,PRPS1,FTSJ3,SF3A1,FAM98A,ANTXR2,LSM12,SMARCAD1,ARHGEF12,IMPDH2,MCM2,SMPDL3B,GNG2,ETFDH,METTL6,EEFSEC,ADAM9,SETD6,DHCR7,FAM118A,PTPN14 |
| 2.273e-02 | -3.78 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | 194 | 35 | 17758 | 2279 |
MINK1,RPS29,MYNN,ZFP36L1,WDR37,PARN,PEX7,VPS72,TIMELESS,VAPB,CORO1A,PEG10,AKAP11,LYST,TERF2,MTHFD1,SOBP,SLC6A16,GPM6A,EVL,MCM2,TPK1,MLLT10,HLA-DMA,IRS1,OXSR1,CAT,SMAD3,INTS9,ALKBH1,MDN1,TSEN2,ZNF532,STK4,KAT6A |
| 2.273e-02 | -3.78 | GSE360_CTRL_VS_T_GONDII_MAC_UP | MSigDB lists | GSE360_CTRL_VS_T_GONDII_MAC_UP | 194 | 35 | 17758 | 2279 |
CAMK1,GAS6,ST3GAL6,GBF1,FOXO3,POM121,MAP2K3,FKBP1A,SREBF2,TRIAP1,ANXA5,KIAA0922,SRRM2,TRIM14,VOPP1,ACADS,CCDC57,DTNB,FAM172A,STAMBP,ATG9A,ATOX1,ATP9B,ATP5D,CHAF1A,HTR7,TPD52L2,AHNAK,SMARCC1,ACOX1,MTMR1,PDCD11,AP2S1,NIT1,MEF2C |
| 2.273e-02 | -3.78 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | 194 | 35 | 17758 | 2279 |
MIF4GD,ITPRIP,DLGAP4,RNF24,JMJD6,CIAPIN1,USPL1,WAC,ZEB1,SLC25A1,MYB,VOPP1,LAMA4,IFNGR2,MYO10,EXOC6B,EPS15L1,RAP1B,ARID1A,AKAP13,FOXRED1,TJAP1,DOT1L,ATXN7,GTF2A1,DNAJC1,CCNT1,SPEN,HERC1,ZNF236,ZNF436,AEN,TMEM219,IFITM2,TRIM36 |
| 2.273e-02 | -3.78 | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | 194 | 35 | 17758 | 2279 |
AOC3,EGR1,FEM1C,B4GALT5,SPRYD7,PPP2R2A,ID2,BHLHE40,MAP2K3,PCDH7,NAMPT,SLC7A11,LPIN2,TANK,NRIP1,CDK12,SAP30,KDM6B,SLC3A2,ANKRD33B,MCL1,ZNFX1,DENND4A,SERP1,HERPUD1,ISG15,DCBLD2,AHNAK,HIF1A,ZNF81,IRAK2,CSRNP1,APAF1,FNBP1L,SLC16A10 |
| 2.274e-02 | -3.78 | macromolecule catabolic process | biological process | GO:0009057 | 918 | 140 | 16441 | 2138 |
CUL7,CUL4A,DCP1B,HECTD3,RCHY1,RNF43,SIRT2,GYG1,BIRC2,UBR5,PABPC4,EDC3,TOM1L1,PCYOX1L,ANAPC1,RPS16,PMAIP1,PHKA1,ANAPC11,ANAPC10,HYAL1,RNF111,LONP1,TRIM13,RBCK1,FBXW4,SKIV2L2,HSPA5,TCEB3,SPOP,KIF16B,NOCT,USP15,CHMP4C,FBXO45,DROSHA,UBXN1,TATDN3,PIK3R4,SMG7,ZFP36L1,CCDC47,PARN,RHBDD1,RNF40,UBE3A,COPS3,CNOT4,LRSAM1,AGL,PABPC1,USE1,EXOSC2,WDR61,USP49,EIF4A2,RNH1,PSMA1,USP10,USP46,HERPUD1,ISG15,ARIH2,UBE2E1,POP1,KPNA1,RPL28,UBAP1,VCAN,ZCCHC6,CNOT6,TBL1X,BRSK2,C18orf25,AGO3,USP7,CYLD,PAPD4,LIN28B,CEMIP,RPS29,PPP2R2A,RIPK1,RNF24,TNKS1BP1,DENND3,LYPLAL1,UBR1,ERI1,UCHL5,SOCS6,TTC3,ETF1,AUP1,HTRA2,PRPF19,SKIV2L,RAB7A,MARCH6,ENC1,EDEM2,UBR4,USP36,FBXL5,CDC16,HYAL3,ARNTL,ATG7,USP11,SMG1,HM13,MLH1,RNASEH2B,PSMF1,NEDD4,UPF2,EXOSC4,FBXO31,ERI3,CD44,FBXL19,LYPLA2,DIS3L2,VPS37A,FGF2,USP42,DHX34,EXOG,UBE2K,UBC,CTIF,FBXO21,GPC2,CUL2,ATM,USP20,NCBP2,TATDN1,ANAPC4,DDIT3 |
| 2.275e-02 | -3.78 | Cell cycle | KEGG pathways | hsa04110 | 124 | 24 | 6908 | 881 |
ZBTB17,MCM6,STAG1,ANAPC13,CDK4,DBF4,TGFB2,MCM2,MAD2L2,SMAD3,ABL1,ANAPC1,CDC16,GADD45A,E2F4,MYC,MCM5,ORC5,ANAPC11,ANAPC10,MAD1L1,ATM,CDK6,ANAPC4 |
| 2.275e-02 | -3.78 | Cell cycle | KEGG pathways | ko04110 | 124 | 24 | 6908 | 881 |
ZBTB17,MCM6,STAG1,ANAPC13,CDK4,DBF4,TGFB2,MCM2,MAD2L2,SMAD3,ABL1,ANAPC1,CDC16,GADD45A,E2F4,MYC,MCM5,ORC5,ANAPC11,ANAPC10,MAD1L1,ATM,CDK6,ANAPC4 |
| 2.277e-02 | -3.78 | muscle structure development | biological process | GO:0061061 | 454 | 74 | 16441 | 2138 |
TCF12,PTCD2,DLL4,ACTG1,NF1,CACNA1H,MYH9,KDM1A,FLNB,SKI,JAG1,ZFHX3,MYH3,CHD2,ETV1,SAP30,FLNC,SIRT6,ANK2,GPCPD1,LGALS1,CAV1,LAMA2,MEF2D,DSP,SERP1,CXADR,DYRK1B,SKIL,CAMK2D,GATA6,MKL2,LARGE,ATG7,DISP1,TPM1,LAMA5,MEF2C,TNNC1,TTN,EGR1,TCF3,SMAD7,BARX2,MBNL1,ABL1,FKBP1A,SNW1,NEBL,CAV2,SOX6,HMGCR,FER1L5,KDM6B,IFRD1,MSX1,PAXBP1,ARID5B,OBSCN,RYR2,SMARCD3,ARID1A,FOXC1,TCF7L2,MKX,SPAG9,LEMD3,TBX3,SVIL,BMP4,RBPJ,NR2F2,PDLIM5,SMYD3 |
| 2.281e-02 | -3.78 | WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT | MSigDB lists | WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT | 56 | 13 | 17758 | 2279 |
DST,KAT8,FN1,DCXR,USPL1,PARP2,RABGAP1L,TOP3A,MCL1,LTB4R,CIAPIN1,HDDC2,PRPF19 |
| 2.281e-02 | -3.78 | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | 56 | 13 | 17758 | 2279 |
ADARB1,SOBP,MAP2K5,METTL8,SLC4A7,COBLL1,PTK2,SYNJ2,UTS2,NRIP1,ADK,ZNF532,MEF2C |
| 2.281e-02 | -3.78 | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | MSigDB lists | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | 56 | 13 | 17758 | 2279 |
C1orf159,EPN2,CHST11,MCAM,FN1,PPFIBP1,CDK4,TPM4,LGALS1,MARCKSL1,MCM2,TPM1,KLF6 |
| 2.281e-02 | -3.78 | EIF4A3 (eukaryotic translation initiation factor 4A3) | protein interactions | 9775 | 243 | 46 | 16036 | 2270 |
SART1,CUL7,FN1,LIN28B,ATP6V1A,PLRG1,MYH9,AARS,HSPA1A,ZC3H13,SMARCB1,SNW1,SRSF2,BCAS2,RNF2,RAN,FBL,YBX3,PRMT5,SRRM2,IPO11,HNRNPM,SF3A1,SRPK2,PRPF19,SPTAN1,SKIV2L2,GNL3,TRA2A,TSN,EIF4A2,WDR18,VIM,PNN,SON,RHOT2,CLNS1A,DDX3X,RPL28,HNRNPR,RIOK1,PGAM5,PDLIM5,BMI1,SRP14,SMG1 |
| 2.283e-02 | -3.78 | Activation of ATR in response to replication stress | REACTOME pathways | R-HSA-176187 | 37 | 10 | 8202 | 1117 |
RFC4,MCM6,RFC3,MCM10,MCM5,ORC5,DBF4,ATRIP,MCM2,RPA1 |
| 2.283e-02 | -3.78 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | REACTOME pathways | R-HSA-110313 | 37 | 10 | 8202 | 1117 |
RFC4,RFC3,POLE2,POLK,RCHY1,USP10,MAD2L2,ISG15,UBC,RPA1 |
| 2.285e-02 | -3.78 | human chr17p13.3 | chromosome location | human chr17p13.3 | 72 | 13 | 26250 | 2590 |
METTL16,TSR1,MYBBP1A,DPH1,PAFAH1B1,RAP1GAP2,NXN,SGSM2,MIR22HG,SLC25A11,VPS53,PITPNA-AS1,RPA1 |
| 2.286e-02 | -3.78 | Arm | pfam domains | PF00514 | 28 | 8 | 16629 | 2165 |
ARMC4,KPNA1,JUP,KPNA3,ARMC6,RAP1GDS1,SPAG6,ARMC3 |
| 2.293e-02 | -3.78 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 181 | 33 | 17758 | 2279 |
PIGM,TRERF1,CNTNAP3,PRKAB2,PDK4,NHS,C14orf159,ATF7IP,HLTF,TGFBR2,IQGAP2,SLC39A11,SLC25A20,METTL16,IFIT5,MED24,ARHGAP1,CORO1A,VCL,OGG1,PRPS1,GTF2H3,TUBA1A,PDE3B,VPS13C,G6PD,SET,PTRH2,ZNF32,SEMA3C,RUNX1,MTMR1,PDSS2 |
| 2.293e-02 | -3.78 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | 181 | 33 | 17758 | 2279 |
DMXL2,NOMO3,C9orf78,CDCP1,LARS2,RCAN1,SSBP2,FAM13A,SOCS1,ASAP1,TAF3,C12orf76,VCL,SAMD3,PTPRK,MSI2,ANTXR2,LIMA1,PPARG,ZMYM5,GPCPD1,SOX4,CPT1A,SLC50A1,GNAI1,OSBPL1A,CAMK2D,FSCN1,INTS5,SVIL,TPM1,RAB30,PTPN14 |
| 2.295e-02 | -3.77 | TAATGTG,MIR-323 | MSigDB lists | TAATGTG,MIR-323 | 155 | 29 | 17758 | 2279 |
GPM6A,AUH,TEAD1,SMARCAD1,EIF3J,DPF2,MARCKSL1,PCNXL2,ADAMTS6,RSBN1,LCLAT1,USP46,RAB10,RPGRIP1L,DDX3X,FAM135A,KPNA1,ENTPD5,KPNA3,TBPL1,ZMYM2,FNBP1L,RNF214,YEATS2,TNRC6A,TMPO,LPP,HS2ST1,TOP1 |
| 2.301e-02 | -3.77 | protein localization | biological process | GO:0008104 | 1685 | 246 | 16441 | 2138 |
IMMP2L,KIF5A,DDX19A,PLRG1,NUP160,SEC16A,TOM1L1,ABL2,SRPRB,EXOC1,RPS16,RAP1A,S100A10,ATG3,NCKIPSD,AP1M1,VPS52,RAN,SEH1L,TIMM50,VPS13B,CDC37,PTPRK,DBN1,GDAP1,NRAS,MIOS,ATG9A,PPARG,WLS,ANK2,EXOC6B,HSPA5,AP4B1,AKAP12,SUMO3,MCL1,CAV1,ZDHHC14,LSG1,PEX1,TIMM44,PAF1,RBSN,EIF4ENIF1,TOM1L2,RLTPR,TNFRSF1A,VPS13D,BBIP1,FIS1,CLU,NRP1,NMD3,ZMAT3,C2CD5,CHMP4C,BANP,HERC2,JUP,CELSR1,SEC24D,CCDC53,VTA1,STXBP6,PRAF2,NKD2,MAPK8IP3,PIK3R4,LAMTOR3,SMAD7,XPO7,SSR4,TIMM10,PITPNM1,RHBDD1,SPIRE1,ABCA7,DOPEY1,CEP290,PPIL2,TNPO3,LRSAM1,ATP6V0D1,TOMM34,TERF2,USE1,TIMM8B,RANBP6,SYNGAP1,XPO5,RAPGEF4,RYR2,OBSCN,MEX3B,AGAP1,HERPUD1,TCF7L2,EXOC6,ATP9B,IRS1,SEC31A,VPS13C,LRP1B,BICD1,KPNA1,NME7,RPL28,NSF,UBAP1,SNAP23,SRP68,SNX24,RRAGA,EXOC4,HK2,SIL1,PEX13,KIAA0196,NAPA,SRP14,SMYD3,TESC,COG5,SNX27,CHMP2A,ID1,OLFM2,PAFAH1B1,ATP6V1A,RPS29,MYO7A,VTI1A,MYH9,NECAP1,NUP43,AP1B1,PIBF1,STAM,GBF1,RPAIN,FLNB,TERF2IP,VPS18,ACD,ABCA12,GRIN2C,PPID,NUP133,DNAJB6,VGF,IKBKB,ZDHHC6,NBEA,BCAP29,AHCYL1,VCL,TSPAN14,DENND1A,IPO11,LYST,AUP1,PRPF19,SEC24A,PHLDB2,RAB7A,ASUN,WDPCP,DLG4,ATP6V0A1,TOR1AIP2,DSP,NUP214,ERC1,SERP1,VPS53,RAB10,PES1,HLA-DMA,RANBP2,KPNA3,DNAJA3,TIMM17A,ATG7,IFT140,NFASC,ANXA2,AP2S1,LAMA5,MID1,TSPAN5,RAB30,PARD3,TMEM33,TNIK,BRAF,HM13,SCAMP3,TRAK1,VPS45,KIF5C,GAS6,MON2,TGFB2,FOXP1,TMCO6,NEDD4,POM121,ABL1,PEX7,TAF3,SEC24C,PMPCA,RDX,DYNC2H1,AMOT,FGF9,CEP83,VPS37A,MSX1,GPHN,AP4S1,MON1A,SCFD2,FERMT2,PACS1,PDE2A,NOP58,ANXA1,MFN2,RERE,YIF1A,CACNB1,ZDHHC11,WDR35,MPP7,STX1A,STX18,VPS37B,RBPJ,GPAM,BMP4,NFKBIB,RABEP1,XPO6,IPO4 |
| 2.301e-02 | -3.77 | RBM39 (RNA binding motif protein 39) | protein interactions | 9584 | 141 | 29 | 16036 | 2270 |
BANP,SNU13,CUL7,UTP14A,TCF3,PLRG1,SIRT7,PNN,SON,SAP30BP,UBC,RPA1,PHC2,DDX3X,TOE1,MLX,CTNNBL1,BCAS2,CDK9,COPS5,GPATCH1,RNF2,RAN,SRRM2,CDK12,TOP1,SRPK2,PRPF19,CLK2 |
| 2.302e-02 | -3.77 | cardiac muscle hypertrophy | biological process | GO:0003300 | 23 | 7 | 16441 | 2138 |
RYR2,CAMK2D,TTN,CAMTA2,GATA6,PDLIM5,MEF2C |
| 2.302e-02 | -3.77 | telomere maintenance via semi-conservative replication | biological process | GO:0032201 | 23 | 7 | 16441 | 2138 |
RFC4,RFC3,POLE2,PRIM2,APEX1,POLA1,RPA1 |
| 2.302e-02 | -3.77 | protein targeting to plasma membrane | biological process | GO:0072661 | 23 | 7 | 16441 | 2138 |
PACS1,GAS6,ANXA2,NFASC,TESC,ANK2,NKD2 |
| 2.306e-02 | -3.77 | V$CREB_Q3 | MSigDB lists | V$CREB_Q3 | 234 | 41 | 17758 | 2279 |
OXNAD1,SPRED2,DNM3,JUP,PRPF31,SEC24D,TMEM183A,C1QTNF7,NAT10,KLHL18,LIAS,CORO6,POGZ,PELP1,HIST2H2AB,PIP4K2A,RING1,JAG1,BRE,SREBF2,ANAPC10,GTF2H1,CHD2,NARS2,SMARCAD1,ZC3H18,JMJD1C,SCFD2,RAP1GDS1,ATP8B2,MBNL2,SAP30BP,USP36,BTBD11,LRP1B,SPAG9,NOL10,VPS37B,GPAM,NOLC1,TMEM33 |
| 2.306e-02 | -3.77 | femur | COSMIC cancer mutations | femur | 1252 | 184 | 17775 | 2278 |
IMMP2L,PIGM,CNTNAP3,KIF5A,CACNA1H,SBF2,CSPP1,CCNL2,TTI1,TMEM132A,SEC16A,PCDH7,ZNF804A,SREBF2,ZFHX3,THADA,ZFYVE28,IPP,RNF111,SUCLG2,ZNF148,CHD2,POLR3B,PRKACB,CHD9,BAZ2A,SLC38A1,KIF15,MCL1,ABCC2,LAMA2,FLVCR1,ZNF197,AHNAK,CCDC146,TNFRSF1A,CSMD3,DNAH2,SYNPO,ZNF598,XYLB,DCTN3,EP400,FOXO1,VTA1,RSF1,CDC73,ETFB,SLC39A11,MTUS1,NAMPT,DOPEY1,C6orf48,HVCN1,SIPA1L3,DHX37,INTS7,CTR9,ATP6V0D1,N4BP2,FMNL2,ZNF675,PRIM2,XPO5,JMJD1C,ZBED4,SETD2,LIG4,OBSCN,EIF2A,EVI5,SYT1,MTR,ABCF1,VAC14,TBC1D2,PRPF40B,DYNC1H1,VPS13C,GRIK4,LRP1B,TASP1,ATAD5,VCAN,FAT1,ZZEF1,SDCCAG8,FDPS,TMEM117,SQLE,KIAA1328,TBCK,DMXL2,DNM3,TRPM2,PCNT,ATP6V1A,HFM1,TNXB,SMARCA4,MYH9,SSBP2,SPATS2,PTPRG,AP1B1,PPP1R9A,EEA1,RPGRIP1L,ZSCAN5A,SHC1,ABCA12,CLCN6,MYH15,TTC3,FHIT,AKNAD1,MAML3,AKAP8L,SSFA2,TFCP2,PREX1,DLG4,ATXN1,GALK2,AKAP13,UBR4,DHX57,ZFAND3,ARMC4,RANBP2,SMARCC1,CLEC16A,TSSC1,LARGE,PRRT3,MDN1,FUS,EIF2B3,TBXA2R,FAHD1,MUTYH,CEP170,SMG1,DMGDH,BRAF,SUPT6H,MRI1,ZNF280C,TRAK1,NSUN6,PDE4B,CLSTN2,RTN4,SEMA3E,MON2,FOXO3,IQGAP2,IL17RE,ZNF483,ADH5,SACS,GART,CTNNBL1,TAF3,UNC13A,RDX,ERRFI1,PLEKHG4,TOP1,DDX24,DHX34,MARS,PACS1,PALLD,EIF5B,ZNF407,SYMPK,YIF1A,RARS,SRCAP,BAZ2B,ORC5,BCAS3,KIF1B |
| 2.309e-02 | -3.77 | Ubiquitin mediated proteolysis | KEGG pathways | ko04120 | 137 | 26 | 6908 | 881 |
HERC2,CUL7,CUL4A,BIRC6,ANAPC13,RHOBTB1,RCHY1,BRCA1,UBE2K,TRIM37,BIRC2,UBR5,UBE2E1,NEDD4,ANAPC1,UBE3A,CDC16,SOCS1,HERC1,CUL2,PPIL2,ANAPC11,ANAPC10,MID1,ANAPC4,PRPF19 |
| 2.309e-02 | -3.77 | Ubiquitin mediated proteolysis | KEGG pathways | hsa04120 | 137 | 26 | 6908 | 881 |
HERC2,CUL7,CUL4A,BIRC6,ANAPC13,RHOBTB1,RCHY1,BRCA1,UBE2K,TRIM37,BIRC2,UBR5,UBE2E1,NEDD4,ANAPC1,UBE3A,CDC16,SOCS1,HERC1,CUL2,PPIL2,ANAPC11,ANAPC10,MID1,ANAPC4,PRPF19 |
| 2.311e-02 | -3.77 | death | biological process | GO:0016265 | 1112 | 167 | 16441 | 2138 |
POLB,CUL4A,NF1,TNFRSF21,TMEM109,CSNK2A1,SIRT2,CHAC1,PRKCA,NLE1,BIRC2,CIAPIN1,MRPS30,NEK6,PMAIP1,ATG3,FNIP2,YARS,AVEN,TIMM50,ATF4,PPARG,C5AR1,MCL1,SHISA5,CAV1,BRCA1,SAP30BP,DDX3X,ZNF622,BRCA2,SH3RF1,ARL6IP5,TNFRSF1A,FIS1,PPP3CC,CLU,ZC3H8,TNFRSF10D,MAGI1,ZMAT3,MTCH1,MEF2C,IFT57,FOXO1,SLK,PAX2,TRIO,DPF2,CDIP1,ZFP36L1,PDCD7,TGFBR2,PDCD5,RHBDD1,DDIT4,PRKCE,MYC,ANP32B,PRF1,PEA15,KRT20,CRADD,STPG1,PSMA1,RYR2,LIG4,OBSCN,SRA1,HERPUD1,MYBBP1A,KPNA1,HK2,RRAGA,PTRH2,DPEP1,BRSK2,ARHGAP10,MAP2K4,SART1,MAP2K5,CYLD,BIRC6,RIPK1,FOSL2,SEMA6A,BLOC1S2,BRE,PPID,DNAJB6,SHF,BCAP29,RMDN3,FHIT,PEG10,KMT2A,CASP10,PERP,CASP8AP2,HTRA2,PRAME,PDK1,DDX41,PARP2,LGALS1,VIM,TMEM123,MEF2D,AKAP13,DSP,SNCA,SMAD3,ZC3H12A,KLF4,HIPK2,DNAJA3,SLC4A7,TRAF3,RPS6KB1,RNF130,BAG1,MAPT,MAP1S,RTN4,MLH1,GAS6,ZNF346,OPA1,TGFB2,NOL3,FOXO3,PHLDA2,PSMF1,MFSD10,ABL1,SNW1,CTNNBL1,DSG2,TRIAP1,NISCH,S100A14,CD44,SPTAN1,TOP1,ARHGEF12,PTK2,IL6R,CAAP1,UBE2K,RHOT2,UBC,MFN2,TRIB3,GADD45A,CUL2,CSRNP1,TMEM219,AEN,ATM,APAF1,PGAM5,IGBP1,RABEP1,KIF1B,ZAK,DDIT3,STK4 |
| 2.311e-02 | -3.77 | cell death | biological process | GO:0008219 | 1112 | 167 | 16441 | 2138 |
POLB,CUL4A,NF1,TNFRSF21,TMEM109,CSNK2A1,SIRT2,CHAC1,PRKCA,NLE1,BIRC2,CIAPIN1,MRPS30,NEK6,PMAIP1,ATG3,FNIP2,YARS,AVEN,TIMM50,ATF4,PPARG,C5AR1,MCL1,SHISA5,CAV1,BRCA1,SAP30BP,DDX3X,ZNF622,BRCA2,SH3RF1,ARL6IP5,TNFRSF1A,FIS1,PPP3CC,CLU,ZC3H8,TNFRSF10D,MAGI1,ZMAT3,MTCH1,MEF2C,IFT57,FOXO1,SLK,PAX2,TRIO,DPF2,CDIP1,ZFP36L1,PDCD7,TGFBR2,PDCD5,RHBDD1,DDIT4,PRKCE,MYC,ANP32B,PRF1,PEA15,KRT20,CRADD,STPG1,PSMA1,RYR2,LIG4,OBSCN,SRA1,HERPUD1,MYBBP1A,KPNA1,HK2,RRAGA,PTRH2,DPEP1,BRSK2,ARHGAP10,MAP2K4,SART1,MAP2K5,CYLD,BIRC6,RIPK1,FOSL2,SEMA6A,BLOC1S2,BRE,PPID,DNAJB6,SHF,BCAP29,RMDN3,FHIT,PEG10,KMT2A,CASP10,PERP,CASP8AP2,HTRA2,PRAME,PDK1,DDX41,PARP2,LGALS1,VIM,TMEM123,MEF2D,AKAP13,DSP,SNCA,SMAD3,ZC3H12A,KLF4,HIPK2,DNAJA3,SLC4A7,TRAF3,RPS6KB1,RNF130,BAG1,MAPT,MAP1S,RTN4,MLH1,GAS6,ZNF346,OPA1,TGFB2,NOL3,FOXO3,PHLDA2,PSMF1,MFSD10,ABL1,SNW1,CTNNBL1,DSG2,TRIAP1,NISCH,S100A14,CD44,SPTAN1,TOP1,ARHGEF12,PTK2,IL6R,CAAP1,UBE2K,RHOT2,UBC,MFN2,TRIB3,GADD45A,CUL2,CSRNP1,TMEM219,AEN,ATM,APAF1,PGAM5,IGBP1,RABEP1,KIF1B,ZAK,DDIT3,STK4 |
| 2.316e-02 | -3.77 | F5_F8_type_C | pfam domains | PF00754 | 23 | 7 | 16629 | 2165 |
BTBD9,NRP1,CNTNAP3,CNTNAP3B,MFGE8,DCBLD2,DDR2 |
| 2.322e-02 | -3.76 | transcription initiation from RNA polymerase II promoter | biological process | GO:0006367 | 251 | 44 | 16441 | 2138 |
NCOR2,TAF1,PRKAB2,SMAD7,LAMTOR3,SKI,DDIT4,SNW1,TAF3,MYC,GTF2H1,MED24,RNF111,MAML3,GTF2H3,SESN2,NR6A1,PPARG,TEAD1,MED27,MED16,MEN1,NR2F1,POLR2A,UBC,TAF9B,VDR,TAF2,SKIL,GLS,SMAD3,GTF2A1,CCNT1,G6PD,E2F4,CDK9,MED15,TAF4,RRAGA,RBPJ,NCOR1,MED20,TAF12,NR2C2AP |
| 2.323e-02 | -3.76 | mesoderm morphogenesis | biological process | GO:0048332 | 67 | 15 | 16441 | 2138 |
SMAD3,KDM6B,HMGA2,TCF7L1,WLS,KLF4,PAX2,ITGA2,TBX3,SETD2,TRIM15,BMP4,ITGB4,FOXC1,DKK1 |
| 2.325e-02 | -3.76 | central | COSMIC cancer mutations | central | 86 | 18 | 17775 | 2278 |
VMA21,NAT10,PCNXL2,WDR37,ARHGEF12,AKAP13,MEN1,ABCA7,IGF2BP3,TMEM132B,DYNC1H1,ASCC3,ZFHX3,HYAL3,ASTN2,EXOC4,LTN1,YEATS2 |
| 2.325e-02 | -3.76 | MUSCLE_DEVELOPMENT | MSigDB lists | MUSCLE_DEVELOPMENT | 92 | 19 | 17758 | 2279 |
TCF12,TTN,IFRD1,NF1,CACNA1H,SIRT2,LAMA2,MEF2D,MBNL1,MKX,GATA6,CACNB2,TBX3,MKL2,MYH3,LARGE,SVIL,BMP4,MEF2C |
| 2.331e-02 | -3.76 | cofactor metabolic process | biological process | GO:0051186 | 318 | 54 | 16441 | 2138 |
MVK,SUCLG1,MRI1,UROD,LIAS,HMOX2,COX10,AHCYL2,NAMPT,FLAD1,GART,CBR4,ATIC,ACOT11,PPCDC,SUCLG2,ME1,SHMT2,AHCYL1,FXN,COQ3,MTHFD2L,TMEM14C,HSD17B12,SLC25A1,MTHFD1,HMGCR,MCEE,PFKFB4,ACSL5,GPHN,ELOVL6,ALDH1L2,PCCA,CPOX,IDH3G,LDHA,MTHFD1L,DLST,MAT2A,PGD,TPK1,MTHFD2,ALAD,HLCS,DCXR,COQ9,G6PD,PEMT,BDH2,HK2,HMBS,GPAM,PDSS2 |
| 2.331e-02 | -3.76 | MSH3 (mutS homolog 3) | protein interactions | 4437 | 26 | 8 | 16036 | 2270 |
EXO1,SLX4,MYC,SMARCAD1,RCHY1,MLH1,BRCA1,RPA1 |
| 2.331e-02 | -3.76 | CENPF (centromere protein F) | protein interactions | 1063 | 26 | 8 | 16036 | 2270 |
CUL7,NUP133,SIRT7,FNTB,SVIL,SNAP25,COPS6,TERF2 |
| 2.338e-02 | -3.76 | PROTEIN_IMPORT | MSigDB lists | PROTEIN_IMPORT | 62 | 14 | 17758 | 2279 |
TAMM41,SMAD3,RANBP2,PEX7,KPNA1,TRIP6,KPNA3,NF1,NCKIPSD,PEX13,NOP58,RPAIN,RERE,PEX1 |
| 2.339e-02 | -3.76 | HALLMARK_ESTROGEN_RESPONSE_LATE | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_LATE | 201 | 36 | 17758 | 2279 |
TNNC1,NCOR2,ABCA3,ID2,SLC29A1,ETFB,FLNB,IGSF1,PLXNB1,HR,RAPGEFL1,CD44,NRIP1,PERP,MYB,FDFT1,TSTA3,HOMER2,CAV1,FOXC1,HPRT1,RBBP8,DCXR,DNAJC1,KLF4,LARGE,HSPB8,SLC16A1,DNAJC12,FKBP5,SCARB1,DHCR7,RABEP1,BAG1,MAPT,GALE |
| 2.343e-02 | -3.75 | Rev-mediated nuclear export of HIV RNA | REACTOME pathways | R-HSA-165054 | 32 | 9 | 8202 | 1117 |
RANBP2,NUP133,RANGAP1,NUP43,RAN,NUP160,NUP214,SEH1L,POM121 |
| 2.345e-02 | -3.75 | posterior_fossa | COSMIC cancer mutations | posterior_fossa | 80 | 17 | 17775 | 2278 |
BRAF,KMT2D,NRAS,ZHX3,SUPT6H,ARHGAP39,IDH3G,SMARCD3,TRAPPC6B,DDX60,FGFR1,SMARCB1,KPNA3,ATG7,ATM,HCFC2,KIAA1549 |
| 2.347e-02 | -3.75 | PDGF_ERK_DN.V1_UP | MSigDB lists | PDGF_ERK_DN.V1_UP | 136 | 26 | 17758 | 2279 |
DDN,MPI,MVK,ST6GAL1,PAX2,PPIP5K2,NUP160,PHLDA2,MRPS11,ANXA10,ATXN7,RARS,SERINC1,ANXA7,CFDP1,ATXN2,SLC39A7,ACOT11,HYAL1,TAF12,NRIP1,CDK6,MID1,TSPAN5,CORO2B,MAML3 |
| 2.348e-02 | -3.75 | NFKBIB (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta) | protein interactions | 4793 | 46 | 12 | 16036 | 2270 |
NCOR2,PPARG,MTIF2,DNAJA3,POLR1A,IKBKB,VPS52,CSNK2A1,POLR1B,POLR1C,GIT2,POLR1E |
| 2.348e-02 | -3.75 | EIF2B3 (eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa) | protein interactions | 8891 | 46 | 12 | 16036 | 2270 |
RFC4,EIF2S2,EIF3C,STC2,EIF2S1,EIF2B3,YBX3,ABCF1,FKBP3,ECH1,HNRNPM,IGF2BP3 |
| 2.348e-02 | -3.75 | TP53RK (TP53 regulating kinase) | protein interactions | 112858 | 46 | 12 | 16036 | 2270 |
METTL1,PRAME,TPD52L2,ACTR3,LAGE3,RANGAP1,VARS,NUP43,PRPS1,PRKACB,SH3GL1,TOM1L1 |
| 2.348e-02 | -3.75 | TANK (TRAF family member-associated NFKB activator) | protein interactions | 10010 | 46 | 12 | 16036 | 2270 |
SMAD3,HERC2,ZC3H12A,USP7,LAMC1,TANK,IKBKB,TRAF3,CEP63,MAP3K14,TRIM37,BIRC2 |
| 2.349e-02 | -3.75 | RNA Polymerase III Transcription Initiation From Type 1 Promoter | REACTOME pathways | R-HSA-76061 | 27 | 8 | 8202 | 1117 |
POLR3D,POLR3E,CRCP,POLR3B,GTF3C3,POLR1C,POLR3A,POLR3G |
| 2.355e-02 | -3.75 | BHATTACHARYA_EMBRYONIC_STEM_CELL | MSigDB lists | BHATTACHARYA_EMBRYONIC_STEM_CELL | 86 | 18 | 17758 | 2279 |
PPAT,ELOVL6,GNL3,IGF2BP2,IMPDH2,TUBB6,ARL5B,SEMA6A,MAD2L2,MGST1,EPRS,DNTTIP1,MTHFD2,DSG2,SET,SLC16A1,SERPINH1,MTHFD1 |
| 2.356e-02 | -3.75 | cardiac muscle tissue development | biological process | GO:0048738 | 147 | 28 | 16441 | 2138 |
KDM6B,TNNC1,PTCD2,TTN,DLL4,SIRT6,SMAD7,ID2,RYR2,ARID1A,TGFB2,DSP,FOXC1,CXADR,FKBP1A,CAMK2D,NEBL,GATA6,DSG2,TBX3,MKL2,ATG7,NDRG4,RBPJ,TPM1,PDLIM5,SOX6,MEF2C |
| 2.357e-02 | -3.75 | transcription-coupled nucleotide-excision repair | biological process | GO:0006283 | 73 | 16 | 16441 | 2138 |
USP7,GTF2H3,RFC4,RFC3,CUL4A,POLK,POLR2A,UBC,RPA1,COPS4,COPS5,COPS3,GTF2H1,COPS7B,COPS6,PRPF19 |
| 2.363e-02 | -3.75 | DESMOCADHERN | prints domains | PR01818 | 7 | 3 | 4759 | 462 |
DSC3,DSC2,DSG2 |
| 2.363e-02 | -3.75 | NCTRNSLOCATR | prints domains | PR00785 | 7 | 3 | 4759 | 462 |
ARNTL2,NPAS2,ARNTL |
| 2.364e-02 | -3.74 | ANX | smart domains | SM00335 | 13 | 5 | 9131 | 1249 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 2.368e-02 | -3.74 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP | 188 | 34 | 17758 | 2279 |
ZNF786,TRIO,ADAMTS6,PELP1,PIP4K2A,RGS17,ZNF827,CD96,AMPD3,PUS3,ASAP1,DHX33,RABGAP1L,MYC,PNPLA3,PRMT3,CRIM1,ARHGEF10,KCNH2,DSP,EXOC6,PRPF40B,TASP1,IKZF4,PDLIM1,HSDL2,STX1A,HIPK2,SLC16A1,DPP4,MDN1,ARC,TBXA2R,SYNPO |
| 2.368e-02 | -3.74 | GSE3982_EOSINOPHIL_VS_TH2_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH2_DN | 188 | 34 | 17758 | 2279 |
CUL4A,EGR1,TTC27,RIBC2,TMEM177,MLH1,XPO7,PIBF1,MFHAS1,FDX1,CAD,PUS3,MRPS27,RAN,PRMT5,FBL,CPSF3L,PERP,C12orf4,PEA15,LDHA,RANGAP1,PALLD,ZDHHC14,TBC1D16,PWP1,SMARCC1,MKL2,SQLE,DPP4,NFRKB,TNFRSF10D,PDLIM5,LAMA5 |
| 2.368e-02 | -3.74 | GSE2197_IMMUNOSUPPRESSIVE_DNA__VS_UNTREATEDIN_DC_DN | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA__VS_UNTREATEDIN_DC_DN | 188 | 34 | 17758 | 2279 |
TNNC1,SARS,CUL4A,TFIP11,MKS1,MAP1S,AKT1S1,UBR5,FAM50A,GART,CNST,CTNNBL1,KDELC1,ACOT11,KIAA0922,LYRM5,SF3A1,TLCD1,AKAP8L,SIGMAR1,TEAD1,POU2F1,MTHFD1L,MTR,C1orf174,PAF1,TASP1,ZNF330,DUSP19,DNAJC12,NCBP2,GPAM,GCSH,NR2C2AP |
| 2.368e-02 | -3.74 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | 188 | 34 | 17758 | 2279 |
STXBP6,B4GALT5,DBF4,CHCHD10,PPIL1,PDCD5,ETFB,FKBP1A,DECR1,COPS4,MARVELD2,BANF1,SDCBP2,MPP6,ALG6,WDR61,LGALS1,MRPS10,TBRG4,PRDM1,SLC35D1,TRIM37,USP46,CENPP,PLIN2,TMCO1,LSS,ALAD,UMPS,EME1,HMBS,ANXA2,LAMA5,PDSS2 |
| 2.368e-02 | -3.74 | GSE17721_CTRL_VS_POLYIC_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDM_UP | 188 | 34 | 17758 | 2279 |
MYCBP2,AUH,MVK,GPBP1L1,CD99L2,SEC16A,SKI,RNF141,RASSF3,KDELC1,BCAP29,POLE3,TSPAN14,C12orf4,RPS6KB2,KLRD1,SLC40A1,CLYBL,CDK4,SMARCAD1,IL6R,ANGPTL4,SLC50A1,CLNS1A,ARHGAP21,HERC1,FDPS,D2HGDH,CDKAL1,ABCC3,HMBS,ADK,MTMR1,ZNF532 |
| 2.368e-02 | -3.74 | RAF_UP.V1_UP | MSigDB lists | RAF_UP.V1_UP | 188 | 34 | 17758 | 2279 |
ARHGAP26,TNFRSF21,RCAN1,FAM13A,ABHD6,FAM49A,NEDD4,MAN1A1,PRKCH,CORO1A,PEG10,CD44,PRPS1,TBC1D8,SKAP2,ABCC4,LAMC1,CRIM1,PPARG,TEAD1,UPP1,ANKMY2,FERMT2,COTL1,KLF6,ANGPTL4,OSBPL1A,TBC1D2,GNAI1,MSX2,DSC2,ACOX1,ERVMER34-1,ABCC3 |
| 2.368e-02 | -3.74 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 188 | 34 | 17758 | 2279 |
TCF12,PRPF38B,ABCA3,CUL4A,ATP6V1A,DDX18,PELP1,CHN1,ABL1,PRKD3,RPS16,TRIAP1,COPS7B,NOC3L,COQ3,TRIM14,PERP,C12orf4,CASP8AP2,NIPSNAP1,PEA15,TSTA3,LIMA1,KLHL23,PWP1,KIAA0355,CUL2,PAM,DPP4,ZNF32,UMPS,COPS6,BLMH,TXN2 |
| 2.368e-02 | -3.74 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | 188 | 34 | 17758 | 2279 |
TBKBP1,MYCBP2,SNX27,SPATA2L,TRIO,TMEM109,CENPB,MAPK8IP3,MED13L,APRT,TRIM22,BHLHE40,FOXO3,RSRC1,PPP1R9A,METTL16,IKZF5,LPIN2,ANKRD11,PCK2,NRIP1,ZNF629,PDK1,ITPA,WDFY3,ARHGEF10,C10orf76,AKAP13,ZSCAN2,TPK1,VPS13C,INSIG1,LARGE,VPS13D |
| 2.368e-02 | -3.74 | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | 188 | 34 | 17758 | 2279 |
ZNF706,NDUFA5,SCAMP3,ITFG1,ALG8,OLA1,SPATS2,AARS,PABPC4,FDX1,NDUFB3,FLAD1,MLX,ASNS,INTS7,THAP4,PPA1,CTC1,SERBP1,SLC25A1,HN1,EIF3J,GNG7,C11orf80,RANGAP1,STOML2,RETSAT,ALG5,FAM114A2,ABHD3,FIS1,NCOR1,AP2S1,LRRC41 |
| 2.369e-02 | -3.74 | INTERPHASE | MSigDB lists | INTERPHASE | 68 | 15 | 17758 | 2279 |
ABL1,CUL4A,KRT7,TAF1,POLA1,KHDRBS1,FOXN3,CDK4,CUL2,DBF4,ANAPC10,TBRG4,TIMELESS,CDK6,ANAPC4 |
| 2.372e-02 | -3.74 | stress fiber | cellular component | GO:0001725 | 51 | 12 | 17570 | 2233 |
PXN,NEBL,FSCN1,LIMA1,TPM4,FERMT2,MYH9,ENAH,PTK2,TPM1,AMOT,FLNB |
| 2.372e-02 | -3.74 | contractile actin filament bundle | cellular component | GO:0097517 | 51 | 12 | 17570 | 2233 |
PXN,NEBL,FSCN1,LIMA1,TPM4,FERMT2,MYH9,ENAH,PTK2,TPM1,AMOT,FLNB |
| 2.374e-02 | -3.74 | NR3C1 (nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)) | protein interactions | 2908 | 165 | 33 | 16036 | 2270 |
NCOR2,CENPB,PBX1,SMARCA4,HMOX2,RPS6KA5,HSPA1A,SMARCB1,PPID,RAN,NRIP1,SF3A1,CHD9,IFNGR2,PPARG,KDM5A,PSMC3IP,POU2F1,SRA1,SYT1,SMAD3,MSX2,SMARCC1,HNRNPR,SET,SVIL,FKBP5,NCOR1,NR2F2,BRCC3,COPS6,TXN2,BAG1 |
| 2.374e-02 | -3.74 | MODULE_159 | MSigDB lists | MODULE_159 | 80 | 17 | 17758 | 2279 |
EIF3C,NARS,EIF3J,EIF4A2,RAP1B,R3HDM1,ARFIP2,AARS,ABCF1,EIF3H,RAB10,EIF2S2,RRAGA,EIF2S1,ETF1,RAN,NOLC1 |
| 2.374e-02 | -3.74 | PID_SMAD2_3NUCLEAR_PATHWAY | MSigDB lists | PID_SMAD2_3NUCLEAR_PATHWAY | 80 | 17 | 17758 | 2279 |
ZBTB17,LAMC1,FOXO1,CDK4,TCF3,SMAD7,FOXO3,SKI,SMAD3,SKIL,VDR,MYC,E2F4,NCOR1,RUNX1,SAP30,MEF2C |
| 2.374e-02 | -3.74 | DNA biosynthetic process | biological process | GO:0071897 | 85 | 18 | 16441 | 2138 |
POLB,RFC4,CUL4A,RFC3,POLK,POLA1,RCHY1,LIG4,USP10,POLG2,MAD2L2,UBC,ISG15,RPA1,MYBBP1A,POLE2,RAD18,POLE3 |
| 2.375e-02 | -3.74 | pleura-mesothelioma-epithelial | COSMIC cancer mutations | pleura-mesothelioma-epithelial | 371 | 61 | 17775 | 2278 |
CGN,DNM3,BRAF,TRERF1,ARID2,NUP160,PITPNM1,AMBRA1,MAN1A1,ABCA7,DST,SNW1,PDZD2,NUP133,CEP290,NVL,THAP4,SEC24C,PDE10A,MYC,ANKRD11,RDX,AKNAD1,YARS,MAP3K12,AUP1,CARM1,TOP1,VPS13B,ARNTL2,KMT2D,RREB1,FAM111B,NOL8,ARHGAP39,C11orf80,SCFD2,RYR2,ATXN1,PEAR1,ZNFX1,RABAC1,PALLD,FGFR1,TPK1,LRP1B,AHNAK,HELZ,EHMT2,SUFU,TECPR2,DISP1,MDN1,ITGB4,PDCD11,ZBTB11,KIF1B,MMP16,DCAF5,PTPN14,TMCC1 |
| 2.377e-02 | -3.74 | Antiviral mechanism by IFN-stimulated genes | REACTOME pathways | R-HSA-1169410 | 70 | 16 | 8202 | 1117 |
EIF4E3,EIF4A2,NUP43,NUP214,NUP160,ISG15,NEDD4,POM121,UBC,FLNB,UBE2E1,RANBP2,KPNA1,KPNA3,NUP133,SEH1L |
| 2.377e-02 | -3.74 | ISG15 antiviral mechanism | REACTOME pathways | R-HSA-1169408 | 70 | 16 | 8202 | 1117 |
EIF4E3,EIF4A2,NUP43,NUP214,NUP160,ISG15,NEDD4,POM121,UBC,FLNB,UBE2E1,RANBP2,KPNA1,KPNA3,NUP133,SEH1L |
| 2.380e-02 | -3.74 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | 74 | 16 | 17758 | 2279 |
SIK3,EGR1,MAP3K13,C19orf43,NSUN6,WWC1,ID2,PITPNB,MBNL2,NAMPT,SLC39A14,HSDL2,ACOX1,MARVELD2,PCSK6,TNRC6A |
| 2.381e-02 | -3.74 | One Carbon Metabolism | WikiPathways | WP241 | 29 | 8 | 4455 | 564 |
GART,MTHFD2,ATIC,SHMT2,MTHFD1L,MTR,AHCYL2,MTHFD1 |
| 2.384e-02 | -3.74 | Type 2 diabetes(PMID:20581827) | GWAS genes | Type 2 diabetes(PMID:20581827) | 14 | 6 | 2389 | 419 |
CDKAL1,IGF2BP2,OASL,RPSAP52,JAZF1,TCF7L2 |
| 2.384e-02 | -3.74 | HIV-1 control(PMID:20041166) | GWAS genes | HIV-1 control(PMID:20041166) | 14 | 6 | 2389 | 419 |
SLCO5A1,NBEA,C6orf48,ZNRD1-AS1,WDR27,TNXB |
| 2.387e-02 | -3.74 | protein phosphatase 2A binding | molecular function | GO:0051721 | 28 | 8 | 16491 | 2164 |
FOXO1,SHC1,SMG7,PPP2R2A,RPS6KB1,IGBP1,MAPT,HMGCR |
| 2.387e-02 | -3.74 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | 175 | 32 | 17758 | 2279 |
RELL2,SSH2,THOC5,BRAF,ST6GAL1,PCSK7,DDIT4,FKBP1A,DOPEY1,DECR1,RAP1A,IKZF5,JAZF1,VCL,RANBP6,TSPYL4,SETD2,GNG7,R3HDM1,MEF2D,COTL1,EDEM2,NUP214,TAF9B,HSPBAP1,BCAS3,MSH3,PTPN4,SGSM2,MTMR1,RFXAP,PPIL3 |
| 2.387e-02 | -3.74 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | 175 | 32 | 17758 | 2279 |
PTP4A1,OXNAD1,PCNT,FAM189B,PDE4B,TIGD1,DDIT4,PRKCE,SPG21,THADA,FHIT,MAP3K12,SNX29,ADARB1,EVL,IL11RA,RAP1GAP2,ARRDC3,SLC35G1,PCNXL2,MEF2D,R3HDM2,ENC1,STK10,ZDHHC11,GADD45A,KLF4,CCDC85B,C3orf35,DTD1,PPP3CC,RPS6KC1 |
| 2.388e-02 | -3.73 | RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase) | protein interactions | 51493 | 62 | 15 | 16036 | 2270 |
RFC4,CUL7,FN1,COPS5,SIRT7,CUL2,FUS,POLR1C,EIF2B3,YBX3,BMI1,ABCF1,HNRNPM,RPS6KB2,IGF2BP3 |
| 2.388e-02 | -3.73 | PCBD1 (pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha) | protein interactions | 5092 | 62 | 15 | 16036 | 2270 |
DYRK1B,CUL4A,ZNF195,COPS5,MYC,CEBPZ,EHMT1,TIMELESS,SCMH1,GTF3C3,SUPT5H,DENND4A,POLR3A,ZBTB25,SAP30 |
| 2.394e-02 | -3.73 | Ribosomal_S5_D2-typ_fold | interpro domains | IPR020568 | 34 | 9 | 18293 | 2341 |
PMS1,MVK,RPS16,TRAP1,GALK2,MLH1,EXOSC4,GFM2,LONP1 |
| 2.394e-02 | -3.73 | SPRTN (SprT-like N-terminal domain) | protein interactions | 83932 | 84 | 19 | 16036 | 2270 |
UBXN1,AKAP12,VIM,TUBB6,HLTF,HIST1H2BL,MLH1,UBR5,HSPA1A,UBC,RPA1,CAD,DYNC1H1,SLX4,SYNCRIP,RAD18,SSBP1,ANXA2,TMPO |
| 2.394e-02 | -3.73 | vasculature development | biological process | GO:0001944 | 462 | 75 | 16441 | 2138 |
IMMP2L,DLL4,CUL7,ID1,LUZP1,MMRN2,NF1,MFGE8,MYH9,PRKCA,CHD7,JAG1,ECM1,SHC1,MMP14,HRG,SRPK2,FMNL3,CAV1,SOX4,FLVCR1,FGFR1,WARS,ZC3H12A,GATA6,MKL2,HOXA3,SLC4A7,SEMA3C,ANXA2,NRP1,LAMA5,PTPN14,MEF2C,EFNB2,EGR1,FOXO1,FN1,ANKRD17,SMAD7,ZFP36L1,JMJD6,SEMA3E,TGFB2,TGFBR2,NEDD4,MCAM,ANP32B,ERRFI1,AMOT,ANGPT2,PKNOX1,FGF9,WARS2,FGF2,SETD2,PRDM1,PTK2,ARID1A,PDE3B,PIK3CB,FOXC1,ANGPTL4,TCF7L2,HIF1A,LEMD3,TBX3,BCAS3,BMP4,RBPJ,NR2F2,DHCR7,DDIT3,STK4,KAT6A |
| 2.397e-02 | -3.73 | CUL5 (cullin 5) | protein interactions | 8065 | 406 | 72 | 16036 | 2270 |
CUL4A,LUZP1,KLHL18,PLOD1,HSPA1A,HNRNPA3,PABPC4,SRSF2,RPS16,ACD,COPS4,ANAPC11,SOCS6,RNF2,SSBP1,CARM1,GARS,RNMT,HSPA5,TOR1AIP2,CCNDBP1,DCUN1D5,GEMIN5,DDX3X,GLS,HPRT1,HNRNPR,COPS5,DNAJA3,SOCS4,ASB3,FUS,COPS6,UNC13D,RHOBTB1,AGO2,HSD17B10,SSR4,PRPF39,PHGDH,NEDD4,NAMPT,DCTPP1,DDX56,GART,ANXA7,COPS3,SHMT2,COPS7B,IGF2BP1,YBX3,AGL,PABPC1,FAM98A,FBXO17,TRA2A,LDHA,HIST1H4J,ARIH2,POLR2A,UBC,HSPA1B,ANXA1,TPD52L2,SYNCRIP,TRAP1,HNRNPH3,CUL2,GPN1,AGO3,LRRC41,STK4 |
| 2.400e-02 | -3.73 | third_ventricle | COSMIC cancer mutations | third_ventricle | 45 | 11 | 17775 | 2278 |
BRAF,NRAS,CLCN6,RNF130,BCOR,MET,CPT1A,KIAA1549,FGFR1,SMARCB1,GNAI1 |
| 2.406e-02 | -3.73 | translesion synthesis | biological process | GO:0019985 | 50 | 12 | 16441 | 2138 |
RFC4,RFC3,CUL4A,RAD18,POLE2,POLK,RCHY1,USP10,MAD2L2,ISG15,UBC,RPA1 |
| 2.408e-02 | -3.73 | BIRC6 (baculoviral IAP repeat containing 6) | protein interactions | 57448 | 41 | 11 | 16036 | 2270 |
HERC2,BIRC6,CA11,TBC1D22A,EPS15L1,SIRT7,ANAPC11,CSNK2A1,GBF1,HTRA2,UBC |
| 2.408e-02 | -3.73 | RBM23 (RNA binding motif protein 23) | protein interactions | 55147 | 41 | 11 | 16036 | 2270 |
ANKRD17,RBFOX2,JMJD6,CEP126,BHLHE40,PRMT5,FBL,CDK6,AHCYL2,RPA1,SRPK2 |
| 2.408e-02 | -3.73 | MLLT3 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3) | protein interactions | 4300 | 41 | 11 | 16036 | 2270 |
PAF1,ELL,MCM6,CCNT1,CDK9,RNF2,BCOR,KMT2A,CDK6,MLLT10,DOT1L |
| 2.408e-02 | -3.73 | V$GCM_Q2 | MSigDB lists | V$GCM_Q2 | 228 | 40 | 17758 | 2279 |
DLL4,CHST11,ANKRD17,PPARGC1B,HFM1,BTBD9,LPCAT3,CORO6,LTB4R,CHD5,MBNL1,SRSF2,ANKRD11,SEMA3D,NLGN3,DIS3L2,SRPK2,KDM3B,TTPAL,BDNF,PPP1R9B,MPP6,ENHO,SCMH1,WWC1,PRDM1,ARID1A,HSD3B7,SPOP,YTHDF2,TCF7L1,KPNA1,GATA6,VCAN,PTRH2,ZNF32,RBPJ,TBL1X,MAGI1,BMI1 |
| 2.411e-02 | -3.73 | human chr11q14.1 | chromosome location | human chr11q14.1 | 30 | 7 | 26250 | 2590 |
NARS2,RSF1,AAMDC,TMEM126B,TMEM126A,RAB30,ALG8 |
| 2.411e-02 | -3.73 | SRSF3 (serine/arginine-rich splicing factor 3) | protein interactions | 6428 | 124 | 26 | 16036 | 2270 |
SCAF11,SLC3A2,CUL7,CUL4A,FN1,UTP14A,DDX18,CLK1,KHDRBS1,TRA2A,SIRT7,TMEM126A,NFIA,NFX1,ATP6V0A1,TMEM177,SRSF2,SYNCRIP,TIMM17A,COPS5,CUL2,BUD31,RNF2,HEATR1,HNRNPM,SRPK2 |
| 2.414e-02 | -3.72 | heart morphogenesis | biological process | GO:0003007 | 212 | 38 | 16441 | 2138 |
TNNC1,PTCD2,TTN,IFT57,DLL4,SMAD7,ID2,RTN4,TGFB2,NEDD4,CHD7,FKBP1A,JAG1,NDRG4,CCDC40,WNT16,MSX1,SIRT6,COL4A3BP,RYR2,SMARCD3,PTK2,SOX4,DSP,FOXC1,SMAD3,MSX2,GATA6,HIF1A,MKL2,TBX3,ARL13B,SEMA3C,RBPJ,BMP4,TPM1,KAT6A,MEF2C |
| 2.414e-02 | -3.72 | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | 34 | 9 | 17775 | 2278 |
BRAF,NRAS,CLCN6,RNF130,BCOR,MET,KIAA1549,FGFR1,GNAI1 |
| 2.418e-02 | -3.72 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 615 | 95 | 17570 | 2233 |
DNM3,CUL7,CYLD,PAFAH1B1,KIF5A,VTI1A,HECTD3,SIRT2,STK33,PRKCA,RAC3,HSPA1A,NOS1AP,SLC30A7,RAP1A,DNAJB6,VPS52,PRKACB,MOSPD1,SEC24A,TRIM13,PPARG,PTPRM,CDK4,ANK2,PREX1,COL4A3BP,AKAP13,CAV1,KCNH2,ODC1,VPS53,RAB10,SNCA,FBXL5,CAMK2D,SH3RF1,COPS5,RPS6KB1,SRFBP1,CLU,FUS,ANXA2,NOCT,DCTN3,STX8,SEC24D,MAP1S,GDPD5,CLINT1,SPIRE1,NEDD4,PRKCE,ABL1,PI4KB,SEC24C,ATXN2,TRIAP1,STC2,UPF2,IGF2BP1,S100A14,YBX3,CALN1,CAV2,SERBP1,ZNF675,BDNF,APEX1,PDE4A,ZFYVE1,RAP1GAP2,EIF4A2,WWC1,RANGAP1,PACS1,SNAP25,PDE2A,TRIM37,CTIF,ATP9B,HSPA1B,SEC31A,INF2,SRCAP,TPD52L2,SPAG9,BICD1,FAT1,SET,USP20,BRSK2,ARHGAP10,PDE9A,DOCK6 |
| 2.419e-02 | -3.72 | MBD1 (methyl-CpG binding domain protein 1) | protein interactions | 4152 | 31 | 9 | 16036 | 2270 |
SMAD3,ATF7IP2,ZNF512B,SMAD7,SHMT2,RNF2,ATF7IP,OASL,CHAF1A |
| 2.419e-02 | -3.72 | TROVE2 (TROVE domain family, member 2) | protein interactions | 6738 | 31 | 9 | 16036 | 2270 |
CARS,SUB1,GARS,GART,PPAT,HIRIP3,JMJD6,XPO7,PRMT3 |
| 2.419e-02 | -3.72 | APLF (aprataxin and PNKP like factor) | protein interactions | 200558 | 31 | 9 | 16036 | 2270 |
POLB,XPC,APLF,PARP2,LIG4,HLTF,XRCC4,HIST2H2AB,TOP1 |
| 2.420e-02 | -3.72 | KPNA1 (karyopherin alpha 1) | protein interactions | 3836 | 73 | 17 | 16036 | 2270 |
CRADD,PRPF31,PLRG1,FANCD2,NOP58,UBR5,NOP56,SUB1,RANBP2,SLX4,CTNNBL1,TP53BP1,COPS5,RAN,ANP32B,FBL,PRPF19 |
| 2.420e-02 | -3.72 | USP5 (ubiquitin specific peptidase 5 (isopeptidase T)) | protein interactions | 8078 | 73 | 17 | 16036 | 2270 |
PMS1,ATP6V1A,SIRT7,LAGE3,MLH1,STK33,UBTD2,UBC,CLNS1A,WARS,YTHDF2,OXSR1,TADA3,RAD18,UBR1,KDM5C,AGL |
| 2.420e-02 | -3.72 | VAMP2 (vesicle associated membrane protein 2) | protein interactions | 6844 | 73 | 17 | 16036 | 2270 |
USP7,UBXN1,LAMTOR3,ATP6V0A1,ABCC2,RABAC1,SNAP25,SYT1,S100A16,PRKD3,TRAP1,STX1A,SNAP23,UBAP2L,VAPB,NAPA,TIMM50 |
| 2.420e-02 | -3.72 | IMPDH2 (IMP (inosine 5'-monophosphate) dehydrogenase 2) | protein interactions | 3615 | 73 | 17 | 16036 | 2270 |
SNU13,CUL7,FN1,PPAT,SIRT6,ASUN,SIRT7,IMPDH2,SLC25A44,NEDD4,PUSL1,RPA1,DDX3X,COPS5,COPS6,PRKAR2A,NMD3 |
| 2.422e-02 | -3.72 | GCM_AQP4 | MSigDB lists | GCM_AQP4 | 45 | 11 | 17758 | 2279 |
RNF141,ARHGAP21,PSAT1,HIPK2,PREX1,TTYH2,RDX,AHCYL1,SAMD4A,FMNL2,PDE8B |
| 2.422e-02 | -3.72 | ARM_REPEAT | prosite domains | PS50176 | 29 | 8 | 11866 | 1504 |
ARMC4,KPNA1,KPNA3,ARMC6,JUP,ARMC5,RAP1GDS1,ARMC3 |
| 2.424e-02 | -3.72 | RODWELL_AGING_KIDNEY_DN | MSigDB lists | RODWELL_AGING_KIDNEY_DN | 130 | 25 | 17758 | 2279 |
KLHL24,AK2,SULT1C2,WDR61,NF1,SLK,GNG7,TRPM6,C1orf226,CSNK2A1,RTN4,PDE3B,MTR,DCBLD2,BTBD11,ADH5,FBXO21,AMPD3,NEBL,ABCA5,CACNB2,UCHL5,CCNB1IP1,NAA35,PPM1K |
| 2.433e-02 | -3.72 | nucleobase-containing compound transport | biological process | GO:0015931 | 186 | 34 | 16441 | 2138 |
THOC5,SUPT6H,DDX19A,KIF5C,SMG7,IGF2BP2,SLC29A1,NUP43,XPO7,NUP160,HNRNPA3,POM121,IGF2BP3,SRSF2,NUP133,ATXN2,UPF2,RAN,IGF2BP1,SLC35C2,CPSF3,SLC25A23,ZC3H3,SEH1L,XPO5,NOL6,SLC35D1,TMEM241,NUP214,RANBP2,SLC25A19,NCBP2,SLC25A26,SMG1 |
| 2.434e-02 | -3.72 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | MSigDB lists | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | 34 | 9 | 17758 | 2279 |
ARNTL2,NPAS2,PER1,ARNTL,SMARCD3,NCOR1,TBL1X,BHLHE40,NAMPT |
| 2.434e-02 | -3.72 | V$PAX8_01 | MSigDB lists | V$PAX8_01 | 34 | 9 | 17758 | 2279 |
HR,FAM172A,OLFM2,IKZF5,LUC7L3,JMJD1C,AHCYL1,TCF7L2,PCDH7 |
| 2.434e-02 | -3.72 | PID_MAPK_TRK_PATHWAY | MSigDB lists | PID_MAPK_TRK_PATHWAY | 34 | 9 | 17758 | 2279 |
RAP1A,MAP2K5,BRAF,NRAS,EGR1,RAP1B,RPS6KA5,MAP2K3,MEF2C |
| 2.436e-02 | -3.71 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 255 | 44 | 17758 | 2279 |
DNAJA4,SLC48A1,ID2,PLEK2,PHLDA2,PITPNM1,PCDH7,DDIT4,TOM1L1,RSPRY1,PRKCH,ATXN7L1,PRKCE,TMEM184A,NBEA,CPNE7,LYST,FDFT1,MSI2,VOPP1,KDM5B,TLE3,GPCPD1,ZNF324B,ST6GALNAC3,C11orf65,KLF6,SERGEF,HSD3B7,TAF9B,BAZ2B,DCXR,TECPR2,WDR7,BCAS3,SLC25A11,RUNX1,MAGI1,FNBP1L,PDLIM5,ZMAT3,MAPT,SLC43A1,CPT1C |
| 2.437e-02 | -3.71 | SEC16A (SEC16 homolog A, endoplasmic reticulum export factor) | protein interactions | 9919 | 36 | 10 | 16036 | 2270 |
AHNAK,SHC1,HNRNPH3,SIRT7,TRAF3,RNF2,HDAC8,CSNK1A1,FKBP3,TERF2 |
| 2.437e-02 | -3.71 | PACSIN1 (protein kinase C and casein kinase substrate in neurons 1) | protein interactions | 29993 | 36 | 10 | 16036 | 2270 |
CARS,ARHGAP17,ASAP1,KHDRBS1,TPM4,ANKRD24,COBLL1,SYNJ1,EHBP1,HSPA1A |
| 2.437e-02 | -3.71 | KPTN (kaptin (actin binding protein)) | protein interactions | 11133 | 36 | 10 | 16036 | 2270 |
RBM33,ELP2,DPH1,KLC4,ELP3,SNX24,KIF5C,NFRKB,IKBKAP,AUP1 |
| 2.437e-02 | -3.71 | HLTF (helicase-like transcription factor) | protein interactions | 6596 | 36 | 10 | 16036 | 2270 |
USP7,SULT1C2,RAD18,S100A10,APLF,CDK9,BRCA1,HLTF,UBC,RPA1 |
| 2.437e-02 | -3.71 | TATDN1 (TatD DNase domain containing 1) | protein interactions | 83940 | 36 | 10 | 16036 | 2270 |
GART,PAFAH1B1,PSPC1,ATIC,RAP1GDS1,CMPK1,GMDS,YARS,LONP1,WARS |
| 2.437e-02 | -3.71 | SP1 (Sp1 transcription factor) | protein interactions | 6667 | 244 | 46 | 16036 | 2270 |
NCOR2,TTN,EGR1,LUZP1,DROSHA,ACTG1,MYH9,CSNK2A1,SMARCA4,ATF7IP,HLTF,BCOR,RSF1,POGZ,SUB1,SHC1,SREBF2,MYC,TIMELESS,SF3A1,DBN1,MSX1,SKIV2L2,PPARG,CDK4,TPM4,ATF7IP2,POU2F1,VIM,BRCA1,MEF2D,KLF6,NR2F1,SMAD3,DDX3X,ARHGAP21,BRCA2,SMARCC1,GATA6,HIF1A,KLF4,TAF4,NCOR1,ANXA2,TPM1,MEF2C |
| 2.439e-02 | -3.71 | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | 195 | 35 | 17758 | 2279 |
NOSTRIN,ATRX,OSBPL9,H2AFJ,ATF7IP,CCDC47,AP1B1,IKBIP,SMARCB1,SLC25A20,ENTPD5,UBR1,CACNB2,MBD2,PPCDC,SOCS6,DTNBP1,NT5C,MAP3K12,C15orf41,TMLHE,MTHFD1,SOBP,RANBP6,FMNL3,PDK1,SIGMAR1,ANKMY2,DHX57,GZF1,RPA1,MSRA,TNFRSF1A,SLC25A26,ANAPC4 |
| 2.439e-02 | -3.71 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 195 | 35 | 17758 | 2279 |
DMXL2,ZNF292,CTU2,TNIK,CYLD,PSTPIP2,DLGAP4,GIT2,PITPNM1,LPIN1,AMPD3,SOCS1,TRMU,ZEB1,SLC16A9,VCL,PLEKHA2,LRSAM1,LYST,SRPK2,TNK2,KDM5B,ANKRD33B,RAP1GAP2,HSH2D,MCL1,DSP,DENND4A,FGFR1,NEU1,SMAD3,SKIL,GADD45A,CLU,TMCC1 |
| 2.439e-02 | -3.71 | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | 195 | 35 | 17758 | 2279 |
BCKDK,FEZ2,ATP6V1A,LAMTOR3,PLOD1,CSNK2A1,CCDC47,TUBB6,ABHD6,ZNF804A,SPG21,ANXA5,SELT,PTGS1,GNG5,HN1,HMGCR,TOP1,SLC3A2,SSFA2,RREB1,CRIM1,WDFY3,HOMER2,RNH1,VIM,PGD,CAT,HLA-DMA,MTHFD2,SERF2,SYNGR2,RNF130,ANXA2,AP2S1 |
| 2.439e-02 | -3.71 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | 195 | 35 | 17758 | 2279 |
MYCBP2,TTC27,CLK1,C16orf52,HECTD3,ADAMTS6,ST7L,MLH1,CSNK1A1,INPP1,IL17RE,ANXA7,ANKRD11,CHD2,FDFT1,PDK1,SFSWAP,MTIF2,ARHGAP39,ZMYM5,USP10,ST6GALNAC3,SLC35F2,POLR3A,MAT2A,HERPUD1,ZBTB25,RPA1,BTBD11,LRP1B,TASP1,ZNF330,TAF4,SQLE,ARHGAP12 |
| 2.439e-02 | -3.71 | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 195 | 35 | 17758 | 2279 |
SEPHS2,IMMP2L,SERINC5,SSH2,CHST11,MCM10,ZCCHC8,RFX1,PBX1,CHAC1,CCNL2,SYNJ1,MTUS1,AMPD3,TSPAN2,NEK6,SLC7A11,AP1M1,NT5E,NARS2,FMNL3,SIK3,SETD1B,ATG9A,PTPN12,LENG8,CXADR,SKIL,BRCA2,GADD45A,CCDC146,ZCCHC6,NCOR1,TMCC1,RNF114 |
| 2.440e-02 | -3.71 | RRM | prosite domains | PS50102 | 211 | 37 | 11866 | 1504 |
NIFK,RBFOX2,PPARGC1B,IGF2BP2,PABPC1L,RBM19,ENOX1,SYNJ1,SAFB2,HNRNPA3,SCAF8,HNRNPLL,PABPC4,IGF2BP3,RBM20,SRSF2,CELF1,IGF2BP1,SYNJ2,CNOT4,PABPC1,HNRNPM,MSI2,SETD1B,PTBP2,PSPC1,TRA2A,NOL8,RBM28,SYNCRIP,HNRNPR,SPEN,HNRNPH3,TRMT2A,NCBP2,RBM26,FUS |
| 2.443e-02 | -3.71 | Integration of provirus | REACTOME pathways | R-HSA-162592 | 9 | 4 | 8202 | 1117 |
LIG4,KPNA1,XRCC4,BANF1 |
| 2.445e-02 | -3.71 | posttranscriptional gene silencing by RNA | biological process | GO:0035194 | 39 | 10 | 16441 | 2138 |
SMAD3,LIN28B,DROSHA,XPO5,AGO2,CNOT6,RAN,CELF1,AGO3,TNRC6A |
| 2.445e-02 | -3.71 | nucleotide-excision repair, DNA incision | biological process | GO:0033683 | 39 | 10 | 16441 | 2138 |
GTF2H3,RFC4,RFC3,CUL4A,POLK,FAN1,GTF2H1,OGG1,UBC,RPA1 |
| 2.445e-02 | -3.71 | regulation of mitophagy | biological process | GO:1903146 | 39 | 10 | 16441 | 2138 |
ZBTB17,WDR75,SREBF2,RPL28,HIF1A,ATG7,HTRA2,AMBRA1,USP36,POLR3A |
| 2.449e-02 | -3.71 | human chr16q24.2 | chromosome location | human chr16q24.2 | 12 | 4 | 26250 | 2590 |
ZCCHC14,FBXO31,C16orf95,ZC3H18 |
| 2.450e-02 | -3.71 | HIST1H4J (histone cluster 1, H4j) | protein interactions | 8363 | 17 | 6 | 16036 | 2270 |
CUL7,FN1,ATRX,UCHL5,COPS5,CUL2 |
| 2.450e-02 | -3.71 | PIGR (polymeric immunoglobulin receptor) | protein interactions | 5284 | 17 | 6 | 16036 | 2270 |
ICE2,HVCN1,TMEM237,SSFA2,CDK6,AP1M1 |
| 2.450e-02 | -3.71 | ASUN (asunder spermatogenesis regulator) | protein interactions | 55726 | 17 | 6 | 16036 | 2270 |
JMJD6,IMPDH2,INTS7,INTS5,C7orf26,ZNF655 |
| 2.450e-02 | -3.71 | RAI1 (retinoic acid induced 1) | protein interactions | 10743 | 17 | 6 | 16036 | 2270 |
GADD45A,RPS6KA5,TESC,SIRT7,DDIT3,MAML3 |
| 2.450e-02 | -3.71 | CASP14 (caspase 14) | protein interactions | 23581 | 17 | 6 | 16036 | 2270 |
FN1,UCHL5,TCF3,CASP10,CUL2,METTL23 |
| 2.450e-02 | -3.71 | DYNLT3 (dynein, light chain, Tctex-type 3) | protein interactions | 6990 | 17 | 6 | 16036 | 2270 |
DYNC1H1,DCTN3,RPS16,TESC,RPS29,SERBP1 |
| 2.451e-02 | -3.71 | SNRPA1 (small nuclear ribonucleoprotein polypeptide A') | protein interactions | 6627 | 130 | 27 | 16036 | 2270 |
SART1,CUL7,PRPF31,PLRG1,SF3A3,ZNF346,S100A16,GEMIN5,DYNC1H1,TOE1,ELL,SNW1,SYNCRIP,PHF5A,UCHL5,BUD31,PRPF4,ICE2,PSAP,SRRM2,CWF19L2,SRP14,GPATCH11,HNRNPM,TOP1,SF3A1,PRPF19 |
| 2.456e-02 | -3.71 | DNA replication factor A complex | cellular component | GO:0005662 | 14 | 5 | 17570 | 2233 |
PURB,BCAS2,PLRG1,PRPF19,RPA1 |
| 2.458e-02 | -3.71 | FBXO6 (F-box protein 6) | protein interactions | 26270 | 618 | 105 | 16036 | 2270 |
ACTG1,DDX18,ATP6V1A,SLC25A21,PLOD1,SMARCA4,TUBB6,IKBIP,TTI1,HSPA1A,PCYOX1L,SRPRB,CAD,FARSA,COPS4,NUP133,KIAA0922,SERPINH1,MET,C6orf89,TRIP13,AUP1,IPO11,TIMM50,CDC37,TMPO,DBN1,GARS,RFC3,TUBA1A,HSPA5,TOR1AIP2,VIM,NUP214,MAT2A,CLNS1A,STOML2,YTHDF2,GEMIN5,DDX3X,TMCO1,HSDL2,HNRNPR,COPS5,SLC25A11,RIOK1,CLU,SCARB1,COPS6,EIF2B3,LAMA5,NOMO3,SCAMP3,ITPRIP,ITFG1,TTC27,SLC25A12,VARS,SSR4,PHGDH,ADGRG6,NDUFS7,IGF2BP3,P3H1,GART,ENTPD5,MCM5,COPS3,VWDE,PTGS1,COPS7B,IGF2BP1,TTC17,PRMT5,PRF1,AMOT,PPA1,PABPC1,PRPS1,HNRNPM,SLC25A1,FDFT1,MTHFD1,LAMC1,ABCF2,LDHA,PSMA1,MARS,IMPDH2,CPT1A,RHOT2,NEU1,HSPA1B,RPA1,RARS,TSR1,EPRS,PXDN,SYNCRIP,RPL28,TRAP1,TAF4,HK2,SIL1,PSAP |
| 2.458e-02 | -3.71 | carcinoma | COSMIC cancer mutations | carcinoma | 17748 | 2278 | 17775 | 2278 |
CDCP1,THOC5,DPH1,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,HMOX2,SLC6A8,ABHD6,LPAR3,CIAPIN1,SKI,IKZF5,ZFHX3,ATP5G2,THAP4,LETM2,MAD1L1,ZNRD1,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,LIMA1,EXOC6B,EHMT1,AP4B1,KIF15,C5AR1,WDHD1,SHISA5,ABCC2,MCM2,PYCR1,SLC7A1,LRRC40,MPV17,DIRAS1,VASH2,ZNF532,SLC25A26,BANP,TRIO,PIK3R4,PARN,CDC73,PITPNM1,RBM20,UBE3A,DHX37,APLF,MED24,WDR60,GEMIN4,PABPC1,PPA1,ANGPT2,KLRD1,GATAD2B,ZNF675,IFRD1,WDR61,ZNF587,IDH3G,MAP7D1,SNAP25,TRIM37,USP46,RDH11,TSR1,C2orf82,KPNA1,NME7,EHMT2,TRAP1,BPNT1,PDLIM5,SRP14,SGSM3,C16orf95,PAFAH1B1,C16orf45,VTI1A,FAM122B,GRINA,ST3GAL6,LCLAT1,ZMAT2,UBL5,MCM9,NDUFB3,CD96,SPG21,ACD,TBC1D22A,SETD5,WAC,MMP14,MGLL,ZC3H3,DENND1A,PMS1,KMT2D,MEF2D,KCNH3,GSTCD,SLC35D1,VPS53,MAT2A,FBXL5,NSMCE2,METTL6,ARL13B,H19,POLR3E,CAMKMT,HOXA3,METTL2B,CEP170,BAG1,MAPT,MORC2,COMMD10,HMGA2,XRRA1,ATG2B,RNASEH2B,ZNF691,POLR3D,TAF3,NOP16,CFDP1,UNC13A,ACOT11,ANXA5,LTN1,PTGS1,RAPGEFL1,ZNF710,ACTR3B,C15orf41,RPL22L1,PNMA1,SPTAN1,DDX24,ZC4H2,ZC3H18,LDHA,CCDC113,CCDC150,ANXA1,MRPL36,NSD1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,TRIM16,FAM13A,FRRS1,AMPD3,COPS4,NCKIPSD,HKR1,METTL8,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,AEBP2,ATF4,MIOS,CDK4,TSN,SUMO3,ODC1,DLST,CRYBG3,MLLT10,DYRK1B,HPRT1,TCF7L1,INSIG1,ADAM9,TSEN2,MAGI1,USP15,CTU2,FOXO1,ITFG1,LAMTOR3,FAN1,ZIC2,C1orf52,LYRM2,SUB1,MBD2,NDRG4,VAPB,CCDC167,WNT16,LRSAM1,SNX29,WARS2,METTL22,CYB5B,TCF7L2,PRPF40B,TTC38,CASS4,PTP4A2,GGT7,DDX10,USP7,ID1,PAPD4,UPK3B,SUCLG1,ARID2,NTSR1,SLC2A1,RADIL,PPP1R9A,PAG1,DDX60L,NUP133,ANKRD24,CCDC40,MYH15,BCAP29,PRPF19,KDM3B,SOBP,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,ANKRD33B,EIF3H,TJAP1,EXO1,IFT81,EIF2B3,MUTYH,PARD3,DMGDH,MCM10,HM13,APRT,RBM19,HIST2H2AB,ANKRD54,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,MON1A,FOXN3,SMARCAD1,TOP3A,ARHGEF12,YIPF3,PALLD,EXOG,POLR3A,DKK1,CDH24,CACNB1,NOL10,L3MBTL3,TAF4,TBX3,BCAS3,ZNF32,TAF12,NR2F2,ZNF292,CUL4A,PRKCSH,PRR4,PRKCA,NBEAL1,LPIN1,S100A10,SUCLG2,CSGALNACT2,ACADS,FAM127A,OSBP2,EFHC1,HIST1H2BL,ZDHHC14,CLNS1A,TMEM206,GZF1,OSBPL1A,SPOP,DOT1L,DDAH2,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,CFD,HIC2,TNFRSF10D,BLMH,BMI1,SPOCK3,ZMAT3,PRPF38B,C9orf78,ST6GAL1,CENPB,DPM3,SSR4,C1orf50,TECTA,MYC,PIGG,EXOSC2,KIAA1143,ANAPC13,RREB1,PRIM2,RAPGEF4,RDH10,RAP1B,ANGPTL4,SLC26A11,MTR,PHF6,ALKBH3,VCAN,SRP68,MED15,BIVM,C7orf50,NCOR1,BIRC6,KIAA0232,TMEM104,PLEK2,PABPC1L,HNRNPA3,BLOC1S2,NUBPL,SLX4,ASNS,DTNBP1,CMPK1,CDK12,SAP30,BRD4,GON4L,LRRC8A,SERP1,HSD3B7,BAZ1A,CAMK2D,WDR5B,MBTD1,CBWD1,SLC4A7,TRAF3,TBXA2R,SETD6,XRCC4,NOSTRIN,BRAF,RCAN1,INPP1,GIGYF2,PHLDA2,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,S100A14,MS4A15,NAV3,TMC7,SLC40A1,PXN,TTLL5,TMEM126B,AGPAT4,TMEM126A,ADSL,PACS1,BMS1,C9orf153,KLF6,INF2,DDX50,IREB2,ATM,APAF1,ADK,IPO4,IMMP2L,PIGM,LETM1,LYRM4,ATRX,SLC52A3,PPIL1,SLC30A7,PCYOX1L,JAZF1,ANAPC11,SLC39A7,MYH3,B3GNTL1,KIAA0922,SLC35C2,CARM1,SRPK2,DTNB,FBXW4,ZNF195,SIRT6,ITPA,VWCE,TMEM216,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ARPC3,TIMM44,YTHDF2,CCDC3,TMCO1,EIF4ENIF1,HLCS,CTAGE5,ASB3,DCTN3,FBXO45,SCART1,SMG7,QSER1,EVPL,NAMPT,RNF141,WDR27,CCDC124,ZCCHC7,PRF1,AKAP11,ZNF629,MTHFD1,MSI2,ZNF234,HBG2,PPAT,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,EIF2A,AGAP1,HERPUD1,UBE2E1,MGAT2,SYCP2L,BICD1,FSCN1,KIAA0355,FDPS,CDKAL1,IFITM2,PDE9A,TCF12,DMXL2,PIGH,SMARCA4,COBLL1,ARSJ,PIBF1,SBDS,RIOK2,RAET1E,RRN3,SOCS1,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,GNG5,C6orf89,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,ATXN1,METTL15,EDEM2,S100A16,ALAD,KPNA3,DUS3L,ZNF557,ARNTL,WDR73,DUSP19,FKBP5,TMEM101,NFRKB,BCKDK,ARL15,KLC4,CHCHD10,SOGA1,PIP4K2A,FAM49A,MFHAS1,PEX7,SEC24C,DCTN4,STC2,LDLRAD3,RPS6KB2,MARCH9,SLC6A16,ARNTL2,DNMBP,GPHN,CRIM1,SULT4A1,SCMH1,ZNF324B,TMEM187,CTIF,DAGLB,GADD45A,AGTPBP1,NFKBIB,ASCC1,CACNA1H,CHAC1,NUP160,SYNJ1,NOS1AP,AMBRA1,TOM1L1,C1orf159,SREBF2,SYN2,PDS5B,LYRM5,HRG,AVEN,CNTNAP3B,MSRB3,PLEKHM3,DCUN1D5,C10orf76,RBM28,TMSB4X,DLEU1,DDX3X,BRCA2,ZNF266,TMEM139,FIP1L1,LPP,MEF2C,TNNC1,CLDN15,TRIP6,NHS,RSF1,CLINT1,DDX56,C6orf48,EIF2S2,KIAA1671,SLC38A5,ALKBH8,NOC3L,PRMT5,CALN1,COQ3,AGL,ZNF518B,FMNL2,SERBP1,HMGCR,FADS1,RB1CC1,MYO10,EIF4A2,CPT1A,ONECUT2,MBNL2,EVI5,ZNF655,NCDN,CLASRP,LEMD3,SURF1,GPN1,CNOT6,WDR33,MB21D2,SPRED2,ABCA3,NPAS2,ATP6V1A,AGAP6,HSPA1A,TMEM150C,PRKD3,ERI1,PYCRL,ATRIP,NT5C,MTHFD2L,KRT7,STAMBP,ARHGEF10,ADAM32,TTC28,FKBP3,PDE8B,HLA-DMA,CDC16,HIPK2,PEMT,PAM,ZBTB11,ANKS1A,YEATS2,TMEM141,TRIM36,C1orf226,WDR37,TGFB2,RSRC1,NPRL2,SUV39H2,TMSB10,ACAP3,ARHGAP1,LYPLA2,HNRNPM,DDHD1,FGF9,POLK,ARHGAP39,FRA10AC1,FAM126B,IL6R,ZNF467,PDE3B,FOXC1,CASC1,KISS1R,ETFDH,PXDN,NME1-NME2,POLE2,PLPPR2,SLC25A19,PSAP,GPAM,IGBP1,NUDT22,DOCK6,CORO2B,KDM4C,BCAS4,FAM227A,GPBP1L1,POLR1A,PPARGC1B,CSNK2A1,RNF43,TMEM132A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,XRCC2,RAN,POLE3,ETV1,MPST,PTPRK,SF3A1,CDC37,TMPO,METTL1,FLNC,CHD9,GCNT2,HARS,ZNF414,SKIV2L2,GDPD1,NOL6,COL4A3BP,GMFB,ATG12,FLVCR1,GLS,ZNF622,TOM1L2,CCDC146,RAD51B,SGSM2,RNF214,XYLB,SARS,AOC3,OXNAD1,RNF40,ABCA5,PDE10A,GTF2H1,SYNJ2,GMDS,NT5E,NAA38,HOMER2,UTP15,RNH1,MEX3B,SUPT5H,TRAPPC6B,NR2F1,PGD,PWP1,FAM135A,ITPRIPL1,SPAG9,SNAP23,DNAH17,TBPL1,ZNF430,PRKAR2A,KCTD7,NDUFA5,CYLD,GPR143,RSL1D1,RNF24,LPCAT3,ZNF709,RPAIN,PELP1,CAD,DUS4L,UBR1,ARMC5,FSIP2,IKBKB,C15orf40,CYB5D1,RNF2,HIBCH,ANO8,CTC1,KAT8,PCGF3,EVL,GLTSCR2,C1QTNF1,MANBAL,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,RBBP8,SLC30A3,CLEC16A,ITGA2,TSSC1,ZNF436,ZNF18,NFASC,SEPT5,ZNF589,PPIL3,ATXN7L2,MAP3K13,ARFIP2,C15orf57,BZW2,IQGAP2,FAM50A,ANXA7,ZNF561,IFIT5,HIST2H3D,PRICKLE2,CD44,HSD17B12,ADAMTSL3,GINS3,DHX34,RAP1GDS1,HIST1H4J,GPNMB,RHOT2,TMEM175,PIK3CB,ARMC3,NEU1,MKX,POLR3G,CENPP,ZRANB3,TPD52L2,ADAT2,GLG1,DNAJC12,RPS6KC1,POLB,MYCBP2,PRDX6,TNFRSF21,ADAMTS6,GIPR,RPS16,RNF111,ME1,SEH1L,TBC1D8,DDN,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,FOXRED1,SKIL,FAM122C,VPS13D,SYNPO,EFNB2,DROSHA,ANKRD17,CCDC53,OPHN1,PID1,TGFBR2,IGF2BP3,ANXA10,FKBP1A,PRKCE,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,COPS3,ATIC,SLC16A9,IGF2BP1,LPCAT1,PRPS1,USE1,SIK3,DDX28,SIGMAR1,AOC2,KIAA0586,PLCB1,ARIH2,LYRM7,ZNF425,EPRS,ZBTB12,D2HGDH,PURB,UMPS,TMEM254,MACROD1,IQSEC2,MAP2K4,ZFHX2,TBKBP1,PTCD2,AMOTL1,TRPM2,CCDC58,RWDD1,LIN28B,SPATA2L,HFM1,SPRYD7,OLA1,C1QTNF7,SPATS2L,TM4SF19,FOSL2,LTB4R,TRIM66,CHD7,FLAD1,TMEM184A,KDM2A,GLYR1,VGF,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,RFC3,WDPCP,KIAA1586,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,DNAJA3,H2AFX,ACP1,TRMT2A,ANXA2,KLHDC4,MDN1,PDCD11,NCOR2,TMEM212,SCAMP3,CA11,TTC27,C10orf2,ZNF280C,SLC25A12,LIAS,MLH1,NOL3,IKBKAP,GDPD5,TMCO6,NEDD4,ZNF239,PTRF,TRIAP1,PMPCA,UPF2,COPS7B,EXOSC4,LARP4B,NT5M,PLEKHG4,C6orf163,TSHZ1,WDFY3,C19orf43,WDR18,APTX,MMAA,ECH1,FBXO21,ZDHHC11,HNRNPH3,STX18,MYOM2,SLC43A1,SLC37A3,MVK,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,PLOD1,ANKRD18A,BCOR,STK33,SNAPC4,AHCYL2,MRPS30,SMARCB1,RTN1,SRPRB,ZNHIT6,GPR87,HYAL1,IPP,PCOLCE2,POLR3B,SLC27A5,CCDC121,OGG1,TRIM14,PRKACB,ELOF1,ZBTB17,TXLNG,SLC38A1,CMIP,LVRN,HDAC8,SOX4,TCTN1,CDHR3,TAF9B,UBTF,RHOU,PAF1,EPN2,GATA6,DNAJC1,MKL2,PQBP1,BBIP1,GALNT10,DMTF1,VIPR1,AK2,CHST11,PIGN,FN1,SEC24D,TAF1,XPO7,CMTM3,ETFB,DDIT4,CEP164,ATXN2,GLTP,POLR1E,N4BP2,CPSF3L,VOPP1,PDE4A,WBSCR22,WWC1,ANKRD20A4,C19orf70,DNAH14,ISG15,UBAP2,MYBBP1A,RRAGA,HK2,PTRH2,ZFP90,TMEM182,ZBTB24,ZNF706,MYO7A,SLC9B2,GBF1,ZSCAN5A,VPS18,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,ZNF142,MET,CPSF3,ZNF460,TMEM14C,HTRA2,MOSPD1,HN1,TMLHE,PHLDB2,COL5A2,FAM172A,TFCP2,SFSWAP,NLN,ATP8B2,RAB10,PUSL1,WARS,ZC3H12A,ADNP,COPS5,SRFBP1,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,C17orf80,H2AFJ,NSUN6,LETMD1,PPP1R1C,HDDC2,SFI1,MAN1A1,MRPS11,PRKCH,GART,TANK,KDELC1,UTS2,AMOT,IL11RA,PSMC3IP,MARS,ARHGAP32,MEN1,ZNF407,MFN2,RERE,ZNF708,ALG5,MPP7,CUL2,NCBP2,ZRANB2,MBD6,TATDN1,MMP16,SLC16A10,HRH1,ARHGAP26,GGT1,PTP4A1,ADAM19,CNTNAP3,MKS1,ZNF44,ZNF37A,MMP7,PDZD2,AP1M1,KDM5C,MSANTD2,SRRM2,EIF4E3,RNMT,KLHL23,UPP1,NFIA,C11orf80,SLC9A5,ZNF197,AHNAK,RAD18,SSU72,SYNGR2,BDH2,RIOK1,RUNX1,TPM1,P2RY11,TMEM63C,EPM2AIP1,FAM189B,BTBD9,PDCD7,CHN1,RSPRY1,CNST,CCDC88C,MRPL21,SAMD3,MYB,RABEPK,NOM1,LRRC20,KCNQ3,ALG6,STAG1,TYW1,ARID5B,USP10,ATAT1,ST6GALNAC3,ARRDC4,SRA1,IRS1,DYNC1H1,RPL28,PDLIM1,GSTO2,FGFBP1,CCDC85B,KIAA0196,ARHGAP10,GALE,SDSL,RAB11FIP4,GTF2H2C,DDR2,MAB21L3,CD99L2,ISG20L2,NUP43,CBWD5,RPGRIP1L,ESAM,ZBED2,ZSWIM7,CLCN6,C16orf58,INTS12,MSH4,PEG10,TRMT12,KIAA1549,LYST,EIF3J,PI4KAP2,ZNF480,FAM171A2,SLCO6A1,PCNXL2,CCNDBP1,NUDT15,DSP,ZFAND3,SLC39A14,ARHGAP21,KDM4B,ELP2,ASTN2,RPS6KB1,CENPBD1,CATSPERG,RAB30,SHQ1,IP6K2,TRIM22,GAS6,PSMF1,TTLL11,SNW1,PSMG4,FBXL19,SAMD4A,TTPAL,VPS37A,LSM12,NXN,RSBN1,PPIP5K2,UBC,OXSR1,SRCAP,HERC1,ERVMER34-1,SRD5A3,CYP24A1,CUL7,RBM33,WDR13,SLC25A21,NLE1,SCAF8,MAP2K3,SRSF2,ECM1,PHF5A,ANKRD11,TRIML2,ZNF3,DSC3,FMNL3,RBCK1,PPARG,ANK2,HSPA5,ATOX1,MARCKSL1,PSMG1,LAMA2,KRTCAP2,KCNH2,LSG1,CXADR,BSN,C1orf122,LSS,CHD3,E2F4,ARL4A,AHNAK2,C3orf35,DPP4,PRPF4,PPP3CC,BEND6,CLK1,PRSS3,NKD2,MAPK8IP3,SMAD7,ARID1B,SPIRE1,RNFT2,MLX,ZNF358,CEP290,VPS72,CTR9,PNPLA3,CWF19L2,NIPSNAP1,USP49,IFT43,HAUS6,SETD2,OBSCN,MAPK1IP1L,ACOXL,TBC1D2,GRIK4,SNX24,SIL1,DTD1,SH3PXD2A,BCCIP,SART1,MPI,OLFM2,SLC48A1,NDUFAF2,RPS29,OSBPL9,LAGE3,RIPK1,SSBP2,TIGD1,DENND3,TNKS1BP1,URB1,ZNF121,SEMA6A,FDX1,PLXNB1,ZNF608,ANKRD13A,NRF1,IDI1,JAG1,GRIN2C,FGGY,AHCYL1,IPO11,TLCD1,ARHGAP17,VIM,NHSL1,CA5B,ZNF251,LMBR1L,KLF4,ATG7,INTS9,MED20,FAHD1,ZNF507,AUH,ESCO1,RFX1,VARS,FOXP1,POGZ,SURF2,CPNE7,SNAPC5,C12orf4,TRNP1,AP4S1,LRRIQ1,ABCF2,C22orf34,KRTCAP3,PLAC8L1,FERMT2,RANGAP1,C8orf33,SMPDL3B,SAMD5,DSC2,CSRNP1,FNTB,TMEM219,USP20,RBM26,RBPJ,XPO6,C6orf223,KIF1B,LMBRD2,LUZP1,GYG1,LRP5L,GABPB2,EXOC1,ZFYVE28,CHD2,SPAG6,ZNF646,GDAP1,C2orf76,VSNL1,CAMSAP2,SON,DENND4A,DDX60,PLCXD2,GNAI1,TRRAP,LUC7L3,XPNPEP1,WDR66,NRP1,RFXAP,NMD3,SPOCK2,CADM4,JUP,CDC42EP2,PRPF31,LARS2,TATDN3,DLGAP4,PRPF39,PDCD5,NDUFS7,MTUS1,FAM192A,HR,SLC7A11,NOVA2,SCAF1,USPL1,LDOC1L,MFAP2,CNOT4,RTFDC1,CAV2,FDFT1,IFNGR2,PCCA,RAP1GAP2,ARID1A,TPRA1,EHBP1,ZNF850,ATP9B,SEC31A,CAT,ASCC3,MTHFD2,C6orf141,HIF1A,SPEN,ZCCHC6,SQLE,DPEP1,CNDP2,DHCR7,SMYD3,HS2ST1,CPT1C,VMA21,SYT17,UROD,POP5,PTPRG,CORO6,FLNB,RING1,IGSF1,NOP56,DECR1,ARMC6,PPID,LPIN2,MRPS27,SOCS6,SHF,TTC3,CASP8AP2,C1orf228,PREX1,PCMT1,SATB2,GNL1,MEGF11,MARCH6,SETD7,ERC1,ZBTB25,SNCA,MSX2,DNTTIP1,SMARCC1,DCXR,G6PD,FTSJ1,LARGE,IFT140,MID1,FGFBP3,SSH2,B4GALT5,KIF5C,FARS2,OPA1,DNAJC22,FAM8A1,CELF1,DYNC2H1,ERRFI1,CLK2,FER1L5,APEX1,PSAT1,ZFYVE1,GUF1,SLC23A2,ZFP62,RETSAT,ZNF155,COQ9,ORC5,SVIL,NDUFS5,DDIT3,ZNF76,EIF3C,RARS2,DST,CNIH3,ZEB1,GPATCH1,HCFC2,YARS,CEP128,TNK2,DEAF1,SESN2,SKAP2,TFPI,ARRDC3,PITPNB,COTL1,ST3GAL5,CC2D1B,FAM114A2,CRCP,CSMD3,EME1,CLU,ZC3H8,DCAF5,MTCH1,ZCCHC8,RHOBTB1,VTA1,STXBP6,UBXN1,PCSK7,TIMM10,ELL,HVCN1,ZNF354A,ISPD,ATP6V0D1,LRP3,HSD17B14,ELOVL6,XPO5,LIG4,CORIN,SYT1,EXOC6,POP1,APBB3,FAT1,KIAA0754,SLC16A1,TMEM117,TBL1X,PFDN2,FNBP1L,TBCK,N4BP2L2,NR2C2AP,SNX27,CHMP2A,DLL4,FEZ2,PSTPIP2,TMEM183A,TNXB,TBCCD1,PBX1,TMEM177,SPATS2,DHX35,ZC3H13,KCTD11,MPHOSPH10,NVL,CBR4,FHIT,VCL,AUP1,PRAME,GRHL3,METTL2A,MRRF,POU2F1,DKC1,UBR4,BATF3,ARMC4,IKZF4,HNRNPR,CEBPZ,RNF130,ARC,BRD9,SMG1,TMCC1,TMEM33,DNAJC2,SUPT6H,DYM,CAMK1,CMTM8,VPS45,PDE4B,MED18,ATF7IP,WDR26,IGF2BP2,SEMA3E,ENOX1,GFM2,BMP6,SCN1B,TMEM99,ERI3,FBL,MICAL3,PKNOX1,TOP1,KDM6B,FGF2,ZNF821,KDM5A,PSPC1,ASAP3,SCFD2,METTL23,PDE2A,EIF5B,NAALADL2,ZNF221,SERINC1,WDR35,VPS37B,ANKRD30BL,POLR1C,ZSWIM6,NIT1,GNB3,WDR74,CSPP1,HLTF,PABPC4,PCDH7,NEK6,NSRP1,PMAIP1,RABGAP1L,FAAH2,RASSF3,C12orf76,WIZ,FNIP2,ZNF148,FXN,CDK6,GNL3,WLS,PTPRM,PACRGL,RFX2,AKAP12,MCL1,SLC50A1,STOML2,SUPT4H1,FIS1,RBP1,CARS,HERC2,EP400,KHDRBS1,SIRT7,PRAF2,PLA2G12A,KCNJ14,SLC1A1,YARS2,SLC39A11,ABCA7,SH2B3,INTS7,MCM5,CACNB2,ZNF326,ANP32B,MAP3K12,TOMM34,PEA15,GTF2H3,BDNF,TIMM8B,COL17A1,TSPYL4,PRDM16,EPS15L1,STPG1,ZNF512B,SMARCD3,RYR2,IMPDH2,ABCF1,ZNF783,VPS13C,LRP1B,TASP1,GTF2A1,ZNF160,COG5,ZNF516,DNM3,TRERF1,DDX18,BTBD2,PDK4,ACTR3,MYH9,NECAP1,TUBB6,SAFB2,STAM,EEA1,RPP30,BCAS2,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,LSM10,PERP,MALL,GARS,FAM111B,NPM3,LGALS1,ATF7IP2,ATP6V0A1,FGFR1,GNG2,TAF2,PES1,IQCH,WDR7,FUS,BRCC3,LAMA5,LRCH1,ZNF786,SERINC5,INSIG2,XPC,SESTD1,TRAK1,ID2,SF3A3,JMJD6,AKT1S1,BHLHE40,MBNL1,POM121,KRI1,TADA3,GATC,PVRL3,SOX6,ULBP1,DIS3L2,NUDC,FAM98A,C21orf58,FBXO17,ERICH1,CLYBL,MRPS10,R3HDM2,UBE2K,DDX49,RPA1,TOE1,RARS,TRIB3,BAZ2B,ARID3B,STX1A,PTPN4,SLCO5A1,ANAPC4,SRM,TFIP11,MFGE8,HECTD3,TTI1,SEC16A,TRMU,UBAP2L,PPCDC,ZNF85,ZNF124,SLC3A2,ABCC4,BAZ2A,KATNAL1,MED27,BRCA1,ZNF91,MGST1,PEX1,KIF16B,CCDC28B,MSRA,TP53BP1,PER1,EEFSEC,TECPR2,SOCS4,TNFRSF1A,DLX2,TMEM158,CHMP4C,SEPHS2,NOMO3,PGPEP1,MCM6,STX8,ITPRIP,LRRC28,C16orf52,MEX3A,HSD17B10,HES6,ZFP36L1,BARX2,TRIM15,RLF,DNAH1,DOPEY1,KIAA1958,SAMD11,PPIL2,TIMELESS,ALDH18A1,CAMKK2,TRAPPC9,LAMC1,CRADD,KTN1-AS1,TLE3,BCS1L,WDR25,ZNFX1,VAC14,NAP1L5,ATXN7,SYNCRIP,PALB2,PPP1R12B,ARHGAP12,HMBS,NAPA,TESC,RNF114,LPCAT2,RBFOX2,PPP2R2A,ZNF83,KDM1A,DENR,METTL16,DNAJB6,ZDHHC6,HIRIP3,ETF1,ZFP37,AKNAD1,CORO1A,PRMT3,CASP10,TMEM200A,SEC24A,SKIV2L,WDR36,TUBA1A,NARS,THSD4,CPOX,TMEM123,ATP5D,BTBD11,SMAD3,RANBP2,SIX5,TIMM17A,ZNF333,ABHD3,PRRT3,PUS1,AP2S1,PKIB,UNC13D,MIF4GD,FAM46B,C14orf159,MAP1S,ZNF346,CSNK1A1,RMI1,ZNF594,PTPN2,SACS,NDUFV1,CWC27,SELT,DDX31,GREB1,PCK2,FBXO31,FAM71E1,ZNF654,ZMYM5,TPM4,TEX14,PEAR1,C11orf49,CHCHD6,C20orf196,TMEM237,SRBD1,GPC2,ZBTB8OS,SET,MSH3,EIF2S1,RWDD2B,ITGB4,MIPOL1,GCSH,CGN,PRKAB2,PLRG1,TMEM109,ENAH,IKBIP,RAC3,AARS,UBR5,MGA,VPS52,PAK1IP1,MEIS3,CEP135,PRADC1,FUT11,DPF3,SLC38A6,NOL8,GNG7,EYA3,TCEB3,CUX1,SEMA3F,MAK16,SAP30BP,SH3GL1,HSDL2,ZNF81,GREB1L,DNAH2,SEMA3C,CCNB1IP1,TXN2,FAM118A,ZNF598,PTPN14,WDR75,IFT57,EGR1,CELSR1,ZHX3,GTF2IRD1,CCDC47,CD226,CHD5,ASAP1,VWDE,SAMD13,GTF3C3,TERF2,ADARB1,SCAF11,SYNGAP1,POLA1,PTPN12,TTYH2,RABAC1,DAGLA,KIDINS220,SERF2,SRRD,NSF,UBAP1,PMEPA1,ZZEF1,RIOK3,PEX13,RTTN,PPDPF,ZBTB37,RIBC2,URB2,NDUFB5,KLHL18,SLC25A44,AP1B1,PDE3A,PAIP2,PHC2,TERF2IP,ZNF827,PUS3,SHC1,UCHL5,NBEA,SSBP1,SERPINH1,PNPLA4,KMT2A,NAA35,C18orf21,MPP6,PDK1,MTIF2,SFXN4,DLG4,GALK2,MED16,PNN,HTR7,YIPF2,ZNF236,ALKBH1,NOLC1,TROVE2,UTP14A,MRI1,TCF3,NFX1,MYNN,RTN4,MON2,REEP5,FOXO3,MAD2L2,DCTPP1,ZNF483,RGS17,COMMD9,LRP2BP,NISCH,RDX,HARS2,NLGN3,MBTPS2,FAM120B,PFKFB4,FZD3,KCNMA1,TBRG4,OASL,NOP58,YIF1A,KLHL22,HELZ,RNF138,PGAM5,BRWD3,RABEP1,STK4,LRRC41,TRPM6,RCHY1,ZNF107,SLC29A1,SIRT2,CUTC,EDC3,WNT2B,ZNF804A,ANAPC1,RAP1A,LONRF2,YLPM1,THADA,ATG3,ANAPC10,RELB,JOSD1,NDUFA6,TRIP13,LONP1,TIMM50,LAMA4,GPM6A,TRIM13,ZNF680,GPCPD1,CAV1,ZSCAN2,SERGEF,CHAF1A,GEMIN5,TMEM132B,SUFU,TRMT5,RLTPR,ABCC3,ZNF397,COPS6,TNRC6A,SLC12A7,RELL2,PAX2,DPF2,ALG8,MED13L,C11orf54,PHGDH,RHBDD1,TOX4,SIPA1L3,MCAM,BANF1,BUD31,SEMA3D,CCDC112,NRIP1,KRT20,RANBP6,TSTA3,TBXAS1,PSMA1,C11orf65,PRDM1,ZSCAN16-AS1,TMEM241,ATAD5,EP400NL,INTS5,SDCCAG8,EXOC4,KIAA1328,C12orf45,PDSS2,C7orf26,ASH1L,PCNT,SLC5A5,CELSR3,MMRN2,ST7L,CSTA,UBTD2,SLC39A1,FARSA,SLC38A2,TSPAN14,MCEE,ACSL5,PTBP2,PARP2,R3HDM1,TOR1AIP2,C1orf174,RAD54B,TPK1,PLIN2,HYAL3,SLC25A11,ECHDC1,NBR2,SH2D3A,SULT1C2,DBF4,PPHLN1,CLSTN2,CCDC7,MFSD10,IL17RE,CTNNBL1,HAS3,DSG2,SHMT2,CLDND1,TTC17,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,PPP1R21,ANKMY2,PHACTR2,LENG8,NAPEPLD,SYMPK,TARS,HSPA1B,ZNF330,PREPL,ZAK,ARHGAP27,CTXN1 |
| 2.458e-02 | -3.71 | positive regulation of binding | biological process | GO:0051099 | 116 | 23 | 16441 | 2138 |
HMGA2,BRD4,PACS1,SIRT2,CAV1,MEN1,HERPUD1,TCF7L2,SKI,ABL2,FKBP1A,ABL1,TRIB3,S100A10,ACD,CDK9,HIPK2,RAN,ANXA2,BMP4,NRP1,MEF2C,STK4 |
| 2.464e-02 | -3.70 | Bromodomain | pfam domains | PF00439 | 39 | 10 | 16629 | 2165 |
BAZ1A,ASH1L,BAZ2B,BRD4,TAF1,BAZ2A,SMARCA4,BRD9,BRWD3,TRIM66 |
| 2.467e-02 | -3.70 | GSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_DN | MSigDB lists | GSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_DN | 182 | 33 | 17758 | 2279 |
TNNC1,USP7,WDR74,TRPM6,TRAK1,TBCCD1,SPATS2L,ZNF44,SEMA6A,TMCO6,SKI,RGS17,SYN2,STC2,ZNF142,SHMT2,TMLHE,TLCD1,TOP3A,SLC26A11,SLC9A5,SAP30BP,S100A16,WARS,SNCA,YIPF2,TMEM139,ZNF430,WDR33,USP11,SETD6,TMEM158,TRIM36 |
| 2.467e-02 | -3.70 | BURTON_ADIPOGENESIS_6 | MSigDB lists | BURTON_ADIPOGENESIS_6 | 182 | 33 | 17758 | 2279 |
NDUFA5,AOC3,SUCLG1,NDUFB5,LIAS,REEP5,NDUFB3,DECR1,MCAM,TANK,ME1,HIBCH,MGLL,FXN,HSD17B12,SLC25A1,ACADS,PSAT1,CYB5B,DLST,MGST1,ATP5D,CAT,RETSAT,ETFDH,ALAD,PEMT,ARL4A,HIPK2,CFD,SCARB1,DHCR7,GCSH |
| 2.467e-02 | -3.70 | GSE14000_UNSTIM_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_UP | 182 | 33 | 17758 | 2279 |
MAP2K5,CAMK1,VPS45,SLC25A44,GIT2,MBNL1,PABPC4,COPS3,TTC3,PTGS1,PRADC1,VCL,TMEM14C,PLEKHG4,LSM10,SNX29,MOSPD1,KAT8,CHD9,SKAP2,TMEM126A,LRRC8A,ATXN1,SATB2,ITPRIPL1,VPS37B,SCARB1,PREPL,TNFRSF10D,CCNB1IP1,TXN2,ZMAT3,HS2ST1 |
| 2.467e-02 | -3.70 | GSE3982_EOSINOPHIL_VS_MAC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAC_UP | 182 | 33 | 17758 | 2279 |
EPM2AIP1,DDX18,CLK1,KIF5A,PIGH,NFX1,CUTC,UBR5,POGZ,UBL5,TOX4,PTPN2,TSPAN2,NUP133,RAPGEFL1,LPCAT1,DSC3,RANBP6,CAMKK2,PTBP2,IDH3G,NXN,POU2F1,CASC1,ISG15,FBXL5,RANBP2,NOL10,HIPK2,PQBP1,BBIP1,MUTYH,USP15 |
| 2.467e-02 | -3.70 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 182 | 33 | 17758 | 2279 |
CYLD,SH2D3A,PCSK7,SBF2,HMOX2,FAM13A,RPS6KA5,DDX60L,GLYR1,ACAP3,TMEM200A,PXN,IFNGR2,UPP1,ARRDC3,CPOX,RSBN1,ARHGEF12,IL6R,SLC26A11,ST3GAL5,STK10,UBC,ANXA1,ZC3H12A,VPS13C,KIAA0355,SPEN,PTPN4,PREPL,TNFRSF10D,PDLIM5,N4BP2L2 |
| 2.475e-02 | -3.70 | actin cytoskeleton | cellular component | GO:0015629 | 445 | 71 | 17570 | 2233 |
CGN,ACTG1,ACTR3,SLC2A1,MYO7A,MYH9,ENAH,CORO6,RAC3,PPP1R9A,FLNB,DST,VPS18,ABL2,MYH3,MAD1L1,IPP,MYH15,CORO1A,VCL,DBN1,LIMA1,SH3GL1,ARPC3,STOML2,SNCA,RHOU,MSRA,AHNAK,DNAJA3,RLTPR,ARC,TPM1,SYNPO,DCTN3,TNNC1,TTN,CCDC53,OPHN1,IQGAP2,ABL1,ELL,NEBL,IFIT5,DCTN4,RDX,TTC17,AMOT,ACTR3B,SPTAN1,PPP1R9B,PXN,MYO10,TPM4,PTPN12,FERMT2,PTK2,ARHGAP32,PALLD,ONECUT2,PEAK1,TARS,APBB3,FSCN1,STX1A,PPP1R12B,SVIL,MYOM2,PDLIM5,SH3PXD2A,CORO2B |
| 2.476e-02 | -3.70 | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP | MSigDB lists | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP | 105 | 21 | 17758 | 2279 |
SARS,IDH3G,NDUFB5,LAGE3,USP10,GAS6,SLC35D1,CYB5B,SON,AARS,MFSD10,RERE,TERF2IP,RAP1A,PPID,SURF1,AHCYL1,CD44,MPST,HRH1,NUDC |
| 2.476e-02 | -3.70 | AAACCAC,MIR-140 | MSigDB lists | AAACCAC,MIR-140 | 105 | 21 | 17758 | 2279 |
TSHZ1,ABCC4,STAG1,ZNF654,ANK2,ZBED4,R3HDM1,TTYH2,SOX4,DHX57,TAF9B,DDX3X,ZNF608,BAZ2B,TSPAN2,HNRNPH3,TBX3,SLC38A2,ADAM9,DPP4,NAV3 |
| 2.476e-02 | -3.70 | human chr10p11.2 | chromosome location | human chr10p11.2 | 7 | 3 | 26250 | 2590 |
ZEB1,SVIL,ZNF37A |
| 2.481e-02 | -3.70 | Beach | smart domains | SM01026 | 9 | 4 | 9131 | 1249 |
NBEA,NBEAL1,WDFY3,LYST |
| 2.482e-02 | -3.70 | YAGI_AML_WITH_INV_16_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_INV_16_TRANSLOCATION | 406 | 66 | 17758 | 2279 |
SPRED2,MAP2K5,NF1,RIBC2,SPRYD7,RPS29,TMEM109,PPP2R2A,SCAF8,LPIN1,RPS16,DUS4L,S100A10,PMAIP1,ETF1,ZNF646,ZCCHC14,COL5A2,SSFA2,TFCP2,BAZ2A,SFSWAP,PARP2,TFPI,PCMT1,ABCC2,VIM,PNN,AKAP13,STK10,GNAI1,HTR7,FBXL5,BRCA2,CLEC16A,SLC4A7,MED20,RUNX1,XRCC4,FOXO1,TAF1,MON2,RNASEH2B,PRKCH,ZNF354A,PI4KB,VPS72,PPIL2,HARS2,PABPC1,NT5E,CRIM1,RB1CC1,HOMER2,DHX34,ARHGEF12,EIF5B,UBC,ECH1,RERE,POLR3G,CAT,IRS1,DYNC1H1,SPEN,ACOX1 |
| 2.483e-02 | -3.70 | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP | 169 | 31 | 17758 | 2279 |
KLHL24,PTCD2,DDX28,PIGM,PRPF38B,MPP6,ANKRD17,GNL3,KIAA0232,USP10,RSBN1,PDCD7,ZNF691,POLG2,ZNF850,LSG1,MRPS11,ZFP62,NSD1,EIF4ENIF1,ITPRIPL1,DAGLB,CDK9,ZNF557,GTF2H1,ZNF148,NOC3L,ZNF397,ZNF3,DDIT3,ZNF646 |
| 2.490e-02 | -3.69 | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | MSigDB lists | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | 296 | 50 | 17758 | 2279 |
MCM6,SCAMP3,SEC24D,DDX18,ISG20L2,PRKCA,KDM1A,FKBP1A,RAP1A,TRIAP1,UBAP2L,RNF2,SSBP1,RAN,FBL,PABPC1,SERBP1,SLC25A1,SRPK2,SAP30,FADS1,DBN1,RFC4,GARS,KDM5B,LAMC1,TUBA1A,CDK4,PCMT1,RAP1B,RAP1GDS1,DKC1,EIF3H,RPA1,PYCR1,HPRT1,RARS,EPRS,SMARCC1,ADNP,FSCN1,COPS5,FTSJ1,SQLE,NCBP2,ANXA2,TAF12,BLMH,TROVE2,AP2S1 |
| 2.494e-02 | -3.69 | Homologous recombination | KEGG pathways | ko03440 | 29 | 8 | 6908 | 881 |
BRCA2,XRCC2,TOP3A,RAD51B,EME1,SSBP1,RAD54B,RPA1 |
| 2.494e-02 | -3.69 | Homologous recombination | KEGG pathways | hsa03440 | 29 | 8 | 6908 | 881 |
BRCA2,XRCC2,TOP3A,RAD51B,SSBP1,EME1,RPA1,RAD54B |
| 2.495e-02 | -3.69 | regulation of organelle assembly | biological process | GO:1902115 | 135 | 26 | 16441 | 2138 |
CHMP2A,FEZ2,CYLD,RAB7A,CEP295,BRCA1,EVI5,TRIM37,TBC1D16,STAM,PIP4K2A,AMBRA1,TBC1D2,FSCN1,TBC1D22A,ATXN2,ATG3,STX18,IFT140,RDX,CNOT6,LRSAM1,SGSM3,MEF2C,TBC1D8,CHMP4C |
| 2.495e-02 | -3.69 | TGCGCANK_UNKNOWN | MSigDB lists | TGCGCANK_UNKNOWN | 518 | 82 | 17758 | 2279 |
PAPD4,PPARGC1B,KLHL18,TBCCD1,SMARCA4,RNF24,LPCAT3,FAM122B,PCDH7,SMARCB1,NRF1,SRSF2,RPS16,ATG3,XRCC2,KDM5C,NDUFA6,SRRM2,ZNF646,TXLNG,ARRDC3,VSNL1,POU2F1,PNN,KRTCAP2,RAB10,SPOP,DDX3X,SUFU,COPS5,MKL2,TSSC1,ACP1,RPS6KB1,ZC3H8,TSEN2,ZMAT3,PKIB,BAG1,BANP,SSH2,MINK1,CA11,MRI1,ATF7IP,RPS6KA5,RSRC1,NPRL2,SNW1,EIF2S2,HR,PTRF,VAPB,UPF2,COQ3,CNOT4,PABPC1,FAM98A,NAA38,FGF9,BDNF,LSM12,POLA1,PSPC1,EIF4A2,EPS15L1,PTPN12,ZNFX1,MARS,LENG8,METTL22,UBE2K,POLR2A,VPS13C,PALB2,GTF2A1,SDCCAG8,CDKAL1,SENP3,NCOR1,RBPJ,NR2F2 |
| 2.502e-02 | -3.69 | KEGG_CELL_CYCLE | MSigDB lists | KEGG_CELL_CYCLE | 124 | 24 | 17758 | 2279 |
ZBTB17,MCM6,ANAPC13,STAG1,CDK4,DBF4,TGFB2,MCM2,MAD2L2,SMAD3,ABL1,ANAPC1,CDC16,GADD45A,E2F4,MYC,MCM5,ORC5,ANAPC11,ANAPC10,MAD1L1,ATM,CDK6,ANAPC4 |
| 2.502e-02 | -3.69 | YAGI_AML_WITH_T_9_11_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_T_9_11_TRANSLOCATION | 124 | 24 | 17758 | 2279 |
EFNB2,KCTD7,RANBP6,AK2,CYLD,NARS,ITPA,TRA2A,JMJD1C,PIGH,ATXN1,POP5,SLC35D1,PALLD,EVI5,FLNB,ZBTB25,WARS,BRE,TBL1X,BMI1,ZBTB11,SRPK2,MEF2C |
| 2.503e-02 | -3.69 | IPO5 (importin 5) | protein interactions | 3843 | 90 | 20 | 16036 | 2270 |
PMS1,CUL7,FN1,SCAMP3,SIRT7,RANGAP1,NUP214,PELP1,RANBP2,DDX56,KPNA1,ACD,ATIC,DTNBP1,HK2,RAN,FBL,IPO4,HSD17B12,RPS6KB2 |
| 2.503e-02 | -3.69 | V$SF1_Q6 | MSigDB lists | V$SF1_Q6 | 242 | 42 | 17758 | 2279 |
SYT17,AK2,C17orf80,KIF5A,MAPK8IP3,GIT2,PABPC4,ANKRD13A,AMPD3,NAV1,NEBL,HAS3,CACNB2,CHD2,TMEM136,VCL,FBXL19,MSI2,TIMM8B,FGF9,SIK3,ZCCHC14,KDM5A,GDPD1,KIAA0586,VSNL1,MEF2D,ST3GAL5,NCDN,FBXO21,EPN2,SLC30A3,SPAG9,TOM1L2,TRAP1,LUC7L3,ABHD3,SOCS4,DIRAS1,MACROD1,XPO6,TNRC6A |
| 2.506e-02 | -3.69 | CTATGCA,MIR-153 | MSigDB lists | CTATGCA,MIR-153 | 202 | 36 | 17758 | 2279 |
EFNB2,ADAM19,FEM1C,FOXO1,PAX2,WDR26,TGFBR2,DDIT4,JAG1,UBR1,MYB,ZCCHC14,CAMKK2,LAMC1,CMIP,SIGMAR1,RYR2,MAPK1IP1L,MCL1,ZNFX1,SNAP25,SYT1,PLCB1,MAT2A,BSN,DOT1L,SNCA,MKX,SLC30A3,HLCS,YIPF2,ARL4A,SLCO5A1,RPS6KB1,BPNT1,MAGI1 |
| 2.518e-02 | -3.68 | EIF4A2 (eukaryotic translation initiation factor 4A2) | protein interactions | 1974 | 57 | 14 | 16036 | 2270 |
DDX3X,SPAG9,ATRX,RPS29,EIF4A2,LAGE3,SLC16A9,BRCA1,PABPC1,VAC14,IPO11,EIF3H,CLNS1A,TRIM36 |
| 2.518e-02 | -3.68 | AKAP9 (A kinase (PRKA) anchor protein 9) | protein interactions | 10142 | 57 | 14 | 16036 | 2270 |
PRKCE,TNIK,PMS1,PCNT,SUV39H2,WAC,RNF2,BMI1,CEP170,PRKAR2A,KDM1A,SAMD3,PRKACB,HNRNPM |
| 2.518e-02 | -3.68 | RING1 (ring finger protein 1) | protein interactions | 6015 | 57 | 14 | 16036 | 2270 |
PHC2,USP7,PCGF3,SMARCAD1,CSNK2A1,RNF2,KDM5C,BCOR,USP11,UBE2K,BMI1,RING1,UBE2E1,TERF2 |
| 2.518e-02 | -3.68 | TRIM33 (tripartite motif containing 33) | protein interactions | 51592 | 57 | 14 | 16036 | 2270 |
SMAD3,SKIL,TCF12,ANAPC1,RFC4,CDC16,DHX33,CDK9,TCF3,SSBP2,NCOR1,RUNX1,ANAPC4,UBE2E1 |
| 2.518e-02 | -3.68 | EAF1 (ELL associated factor 1) | protein interactions | 85403 | 57 | 14 | 16036 | 2270 |
ELL,SART1,TFCP2,CDK9,LUC7L3,FGGY,SFSWAP,RSBN1,ICE2,FIP1L1,MIPOL1,PIP4K2A,NOS1AP,TOP1 |
| 2.518e-02 | -3.68 | DCP2 (decapping mRNA 2) | protein interactions | 167227 | 57 | 14 | 16036 | 2270 |
GARS,TRRAP,INTS7,DCP1B,AGO2,ELP3,AP1M1,FANCD2,TRMT2A,UPF2,GGT7,IKBKAP,TARS,EDC3 |
| 2.524e-02 | -3.68 | Dynein_heavy_chain_D4_dom | interpro domains | IPR024317 | 14 | 5 | 18293 | 2341 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 2.531e-02 | -3.68 | HSPA8 (heat shock 70kDa protein 8) | protein interactions | 3312 | 344 | 62 | 16036 | 2270 |
DNAJC2,INSIG2,DNAJA4,BRAF,CUL4A,FN1,LRRC28,FAM189B,WDR37,HLTF,HSPA1A,HNRNPA3,AMBRA1,TADA3,CAD,TTC1,ABL1,POLR3D,UBE3A,SHC1,BCAS2,PPID,DNAJB6,SEC24C,SSBP1,YARS,PABPC1,RPS6KB2,TUBA1A,SIRT6,CDK4,HSPA5,POU2F1,ATXN1,MCL1,BRCA1,KCNH2,METTL22,MEN1,SON,USP46,UBC,ISG15,RPA1,SNCA,SEC31A,RBSN,HIF1A,DNAJC1,DNAJA3,COPS5,CUL2,CAMKMT,FDPS,TNFRSF1A,PPP1R12B,GPN1,FUS,COPS6,PARD3,MAPT,BAG1 |
| 2.538e-02 | -3.67 | mixed | COSMIC cancer mutations | mixed | 150 | 28 | 17775 | 2278 |
ABCA3,BRAF,NRAS,NF1,JMJD1C,PDE4B,PREX1,TRPM6,MKS1,SMARCA4,OBSCN,RNF43,WDR26,GBF1,RPGRIP1L,EDC3,PDE8B,CENPP,EXOC1,KDM2A,HERC1,ITGA2,INTS12,GSTA4,FUS,MET,WDR66,KMT2A |
| 2.539e-02 | -3.67 | endometriosis | COSMIC cancer mutations | endometriosis | 14 | 5 | 17775 | 2278 |
ARID1A,BRAF,BRCA1,NRAS,MAP2K4 |
| 2.539e-02 | -3.67 | cellular macromolecule catabolic process | biological process | GO:0044265 | 779 | 120 | 16441 | 2138 |
USP7,CUL7,CUL4A,CYLD,LIN28B,PAPD4,DCP1B,RPS29,HECTD3,RCHY1,PPP2R2A,RIPK1,RNF24,RNF43,SIRT2,DENND3,TNKS1BP1,BIRC2,UBR5,PABPC4,EDC3,TOM1L1,PCYOX1L,ANAPC1,RPS16,PMAIP1,ERI1,UBR1,UCHL5,ANAPC11,ANAPC10,SOCS6,RNF111,ETF1,TTC3,LONP1,HTRA2,AUP1,PRPF19,SKIV2L,TRIM13,RBCK1,FBXW4,SKIV2L2,RAB7A,HSPA5,TCEB3,MARCH6,EDEM2,ENC1,UBR4,USP36,SPOP,FBXL5,CDC16,ARNTL,USP11,NOCT,SMG1,USP15,CHMP4C,FBXO45,DROSHA,UBXN1,TATDN3,SMG7,ZFP36L1,CCDC47,MLH1,RNASEH2B,PARN,PSMF1,NEDD4,RNF40,UBE3A,COPS3,UPF2,EXOSC4,FBXO31,ERI3,CNOT4,FBXL19,PABPC1,DIS3L2,EXOSC2,VPS37A,WDR61,USP49,EIF4A2,USP42,DHX34,RNH1,PSMA1,USP10,EXOG,UBE2K,USP46,HERPUD1,UBC,ISG15,ARIH2,UBE2E1,CTIF,POP1,FBXO21,KPNA1,RPL28,UBAP1,CUL2,ZCCHC6,USP20,ATM,NCBP2,CNOT6,TBL1X,TATDN1,C18orf25,ANAPC4,AGO3,DDIT3 |
| 2.541e-02 | -3.67 | establishment of localization in cell | biological process | GO:0051649 | 1843 | 267 | 16441 | 2138 |
THOC5,PRKAB2,DDX19A,ENAH,NBEAL1,NUP160,SYNJ1,TOM1L1,EXOC1,RPS16,NSRP1,PMAIP1,SYN2,ATP5G2,AP1M1,VPS52,HRG,SEH1L,GDAP1,WLS,EXOC6B,AP4B1,CUX1,AKAP12,ZDHHC14,TMSB4X,STOML2,RBSN,BRCA2,CFD,VPS13D,FIS1,NMD3,HERC2,IFT57,OPHN1,PIK3R4,SSR4,CLINT1,SLC1A1,PRKCE,TNPO3,TOMM34,RABEPK,USE1,TIMM8B,BDNF,MYO10,RAPGEF4,RYR2,SNAP25,EVI5,CPT1A,ATP9B,SEC31A,DYNC1H1,VPS13C,KPNA1,KIDINS220,NME7,RPL28,NSF,HIF1A,SRP68,PEX13,SRP14,SGSM3,COG5,RAB11FIP4,SYT17,PAFAH1B1,ACTR3,VTI1A,MYH9,AP1B1,STAM,EEA1,BLOC1S2,ACD,ABCA12,VGF,DTNBP1,NBEA,ZC3H3,DENND1A,LYST,ERC1,VPS53,SNCA,ARHGAP21,IFT140,ANXA2,RAB30,MAPT,TRIM36,SCAMP3,TRAK1,SLC25A12,KIF5C,GAS6,MLH1,MON2,OPA1,TGFB2,NOL3,RSRC1,TMCO6,NEDD4,UNC13A,NISCH,PMPCA,SDCBP2,UPF2,NLGN3,DYNC2H1,FGF9,VPS37A,WDFY3,PACS1,PTK2,NOP58,UBC,ANXA1,ZDHHC11,STX1A,STX18,ATM,GPAM,PSAP,DDIT3,IPO4,IMMP2L,BCAS4,NF1,KIF5A,SEC16A,SRPRB,SRSF2,CNIH3,ATG3,NCKIPSD,RAN,TIMM50,CDC37,ABCC4,ANK2,HSPA5,ATOX1,NOL6,COL4A3BP,FLVCR1,LSG1,MPC1,TIMM44,KIF16B,PEX1,GLS,TOM1L2,CTAGE5,SGSM2,CLU,C2CD5,CHMP4C,TTN,STX8,FN1,SEC24D,STXBP6,VTA1,NKD2,SMG7,XPO7,TIMM10,RHBDD1,SPIRE1,MLX,VAPB,RANBP6,TRAPPC9,IFT43,XPO5,TRAPPC6B,SYT1,BLOC1S4,TCF7L2,HERPUD1,EXOC6,SPAG9,BICD1,MYBBP1A,SNAP23,HK2,EXOC4,SIL1,BRSK2,NAPA,FNBP1L,TESC,CHMP2A,SNX27,OLFM2,RPS29,GPR143,MYO7A,PIBF1,DENND3,RPAIN,GBF1,VPS18,NUP133,ZDHHC6,SLC38A2,BCAP29,CORO1A,AHCYL1,CPSF3,VCL,AUP1,IPO11,SEC24A,TUBA1A,RAB7A,ATXN1,AKAP13,NUP214,RAB10,ATP5D,IFT81,RANBP2,KPNA3,TIMM17A,COPS5,NFASC,SEPT5,AP2S1,PARD3,SMG1,UNC13D,HM13,CAMK1,VPS45,MAP1S,FOXP1,ANKRD54,SLC25A20,PEX7,SEC24C,DCTN4,MICAL3,PCSK6,AP4S1,MON1A,FGF2,SCFD2,PDE2A,RHOT2,RERE,MFN2,CACNB1,WDR35,TBX3,SET,VPS37B,NCBP2,RBPJ,KIF1B,XPO6 |
| 2.541e-02 | -3.67 | MODULE_325 | MSigDB lists | MODULE_325 | 51 | 12 | 17758 | 2279 |
SLC40A1,MSX2,DECR1,PMEPA1,VTA1,MED24,UMPS,EDEM2,MMP16,TOMM34,STK4,SPOP |
| 2.541e-02 | -3.67 | PID_CASPASE_PATHWAY | MSigDB lists | PID_CASPASE_PATHWAY | 51 | 12 | 17758 | 2279 |
CRADD,SLK,TNFRSF1A,RIPK1,VIM,PTK2,APAF1,PRF1,BIRC2,CASP10,SPTAN1,TOP1 |
| 2.541e-02 | -3.67 | chr6q21 | MSigDB lists | chr6q21 | 51 | 12 | 17758 | 2279 |
LAMA4,SOBP,PEX7,LIN28B,TUBE1,PRDM1,COQ3,PDSS2,FOXO3,SLC16A10,PKIB,ZBTB24 |
| 2.541e-02 | -3.67 | NUCLEAR_CHROMOSOME | MSigDB lists | NUCLEAR_CHROMOSOME | 51 | 12 | 17758 | 2279 |
TERF2IP,TTN,ACD,ATRX,POLA1,NOL6,PAM,TIMELESS,PURB,HDAC8,FOXC1,RPA1 |
| 2.543e-02 | -3.67 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 189 | 34 | 17758 | 2279 |
ZNF516,PRDX6,C10orf2,LAGE3,CHAC1,ABHD6,BZW2,SRPRB,ZNF804A,AMPD3,TNPO3,SHMT2,NDUFA6,TBC1D8,ZNF124,SSFA2,ABCC4,AKAP12,MRPS10,CAMSAP2,PTK2,SOX4,EVI5,ARPC3,SLC7A1,PMEPA1,FAT1,ADAM9,SIL1,DNAJC12,PFDN2,NRP1,SMYD3,NMD3 |
| 2.543e-02 | -3.67 | CAMP_UP.V1_UP | MSigDB lists | CAMP_UP.V1_UP | 189 | 34 | 17758 | 2279 |
TNIK,NDUFB5,LETMD1,RCHY1,NFX1,C14orf159,AARS,SNW1,NDUFV1,PMAIP1,ATP5G2,MYC,CCDC124,PXK,AHCYL1,LONP1,IFRD1,RBCK1,ATF4,SESN2,UPP1,HSPA5,MRRF,MARS,RHOT2,SPOP,CHAF1A,MTHFD2,SIL1,SLC25A11,SCARB1,CNDP2,EIF2B3,IPO4 |
| 2.543e-02 | -3.67 | GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 189 | 34 | 17758 | 2279 |
ASH1L,EGR1,PAFAH1B1,B4GALT5,PIK3R4,MON2,RLF,RPS6KA5,GIGYF2,PUS3,ZNF586,USPL1,CACNB2,ZNF234,DNMBP,ANAPC13,WDFY3,ZNF654,USP10,LIG4,MCL1,C11orf49,HIST1H2BL,SON,KLF6,FOXC1,SPOP,PLIN2,TSSC1,VPS13D,PTRH2,RBPJ,XRCC4,ZBTB24 |
| 2.543e-02 | -3.67 | CHANDRAN_METASTASIS_UP | MSigDB lists | CHANDRAN_METASTASIS_UP | 189 | 34 | 17758 | 2279 |
FBXO45,MYCBP2,EP400,FN1,BIRC6,PRKAB2,TRIO,HES6,DDIT4,LONRF2,ATXN2,ARHGAP1,ZNF148,CELF1,PABPC1,HN1,MSI2,HMBOX1,KDM5A,C19orf43,NOL8,C11orf80,MINA,SOX4,TARS,DYNC1H1,NSD1,FSCN1,VCAN,SLC16A1,PDLIM5,LRRC37A,SMG1,TMCC1 |
| 2.543e-02 | -3.67 | GSE14308_TH1_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_TH1_VS_NATURAL_TREG_DN | 189 | 34 | 17758 | 2279 |
DNAJA4,PPP2R2A,BTBD9,TTI1,CIAPIN1,CEP164,CAD,FAM50A,SIPA1L3,VPS13B,HSD17B14,LRRC20,KDM5B,FAM172A,TFCP2,C2orf76,SCMH1,RAP1GDS1,KCNH2,PDE2A,MFN2,ATXN7,DDX50,BAZ2B,HLCS,LUC7L3,ORC5,PAM,SVIL,DPEP1,TBL1X,BRD9,TXN2,TMCC1 |
| 2.546e-02 | -3.67 | human chr2q33.1 | chromosome location | human chr2q33.1 | 37 | 8 | 26250 | 2590 |
FTCDNL1,SATB2-AS1,GTF3C3,SPATS2L,FAM126B,NOP58,PPIL3,CCDC150 |
| 2.546e-02 | -3.67 | human chr11q12.2 | chromosome location | human chr11q12.2 | 37 | 8 | 26250 | 2590 |
DAGLA,AHNAK,VWCE,TMEM109,TKFC,TMEM132A,PRPF19,MS4A15 |
| 2.547e-02 | -3.67 | pituitary | COSMIC cancer mutations | pituitary | 428 | 69 | 17775 | 2278 |
DMXL2,TBKBP1,ABCA3,PCNT,ARID2,RARS2,FANCD2,SMARCA4,RSL1D1,ZNF107,ZNF83,BCOR,PELP1,SKI,RTN1,DHX33,NT5C,CHD2,ETF1,ZNF3,CASP8AP2,CSGALNACT2,FMNL3,NRAS,ATG9A,ALDH1L2,ARHGEF10,LAMA2,SON,ZNF91,DDX60,UBR4,DHX57,RBBP8,BRCA2,TRRAP,KLF4,ZNF598,PARD3,PTPN14,DMGDH,BRAF,ITPRIP,RFX1,WDR37,QSER1,USPL1,NISCH,UNC13A,DDX31,ACTR3B,HMGCR,ZNF675,SLC40A1,PRDM16,KDM5A,KCNMA1,OBSCN,RSBN1,PHACTR2,MAP7D1,MEN1,C8orf33,MBNL2,TBC1D2,ZNF708,DNAH17,ZNF430,ARHGAP12 |
| 2.550e-02 | -3.67 | ATXN1 (ataxin 1) | protein interactions | 6310 | 257 | 48 | 16036 | 2270 |
DCTN3,USP7,NCOR2,TRIP6,ZHX3,FAM46B,RBFOX2,CDIP1,HSPA1A,HNRNPLL,POM121,TOX4,ZNF804A,ASNS,SREBF2,DHX37,ELP5,ATXN2,UBAP2L,LRSAM1,CDK6,ATP6V0D1,NARS,PPAT,EHMT1,RAPGEF4,SETD2,VSNL1,R3HDM1,ATXN1,PRDM1,R3HDM2,ARHGAP32,SUPT20H,UBE2E1,MSX2,EIF4ENIF1,CLASRP,SIX5,DNAJA3,SPEN,FDPS,MED15,PQBP1,RBM26,NCOR1,ITGB4,KAT6A |
| 2.553e-02 | -3.67 | REACTOME_METABOLISM_OF_PORPHYRINS | MSigDB lists | REACTOME_METABOLISM_OF_PORPHYRINS | 14 | 5 | 17758 | 2279 |
HMBS,ALAD,HMOX2,CPOX,UROD |
| 2.553e-02 | -3.67 | RIBONUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | RIBONUCLEOTIDE_METABOLIC_PROCESS | 14 | 5 | 17758 | 2279 |
UMPS,AMPD3,CMPK1,ADK,OLA1 |
| 2.553e-02 | -3.67 | ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS | MSigDB lists | ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS | 14 | 5 | 17758 | 2279 |
MSX2,MSX1,ATF4,TXLNG,FOSL2 |
| 2.553e-02 | -3.67 | DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY | MSigDB lists | DNA_DIRECTED_DNA_POLYMERASE_ACTIVITY | 14 | 5 | 17758 | 2279 |
POLB,POLE3,POLE2,POLG2,POLA1 |
| 2.553e-02 | -3.67 | PROTEIN_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | PROTEIN_METHYLTRANSFERASE_ACTIVITY | 14 | 5 | 17758 | 2279 |
NSD1,SUV39H2,CARM1,EHMT1,PCMT1 |
| 2.553e-02 | -3.67 | MODULE_547 | MSigDB lists | MODULE_547 | 14 | 5 | 17758 | 2279 |
ZNF266,AHNAK,NUDT22,CPSF3L,MGA |
| 2.554e-02 | -3.67 | BASSO_B_LYMPHOCYTE_NETWORK | MSigDB lists | BASSO_B_LYMPHOCYTE_NETWORK | 137 | 26 | 17758 | 2279 |
FAM98A,RFC4,GARS,CYLD,WDR18,DBF4,LGALS1,BHLHE40,HDDC2,PES1,SLC39A14,HPRT1,ASNS,AHNAK,NOP16,TIMM17A,NISCH,ORC5,BUD31,EIF2S1,SSBP1,CD44,BLMH,TRIP13,SERBP1,N4BP2L2 |
| 2.557e-02 | -3.67 | CELL_DEVELOPMENT | MSigDB lists | CELL_DEVELOPMENT | 568 | 89 | 17758 | 2279 |
FEZ2,CUL4A,BIRC6,NF1,CACNA1H,RIPK1,FOSL2,IKBIP,PRKCA,HSPA1A,CIAPIN1,MRPS30,RTN1,BRE,ASNS,PMAIP1,DNAJB6,AVEN,YARS,CDK6,CASP10,CASP8AP2,SPAG6,RTN4RL2,DEAF1,DDX41,LGALS1,ATG12,MCL1,BRCA1,SON,SAP30BP,ERC1,SNCA,SMAD3,DDAH2,LUC7L3,FIS1,TRAF3,EIF2B3,TNFRSF10D,NRP1,MTCH1,PARD3,BAG1,MAPT,TTN,IFT57,BRAF,FOXO1,PAX2,DPF2,OPHN1,MAP1S,RTN4,IP6K2,AKT1S1,NOL3,ZNF346,PDCD7,OPA1,TGFB2,PDCD5,FOXO3,PHLDA2,MBNL1,PRKCE,ABL1,CEP290,CACNB2,TRIAP1,ANXA5,PEA15,IFRD1,CRADD,RHOT2,SRA1,ANGPTL4,HSPA1B,ANXA1,GADD45A,CUL2,TBX3,RRAGA,BMP4,APAF1,BRSK2,ZAK,STK4 |
| 2.563e-02 | -3.66 | PRKAR1A (protein kinase, cAMP-dependent, regulatory, type I, alpha) | protein interactions | 5573 | 79 | 18 | 16036 | 2270 |
CUL7,PRPF31,CDK4,AGO2,MYO7A,SETD7,MEN1,UBC,STOML2,ARPC3,DYRK1B,NPRL2,SLC38A5,SET,AKAP11,PRKACB,MAPT,AGO3 |
| 2.564e-02 | -3.66 | 3'-5' exonuclease activity | molecular function | GO:0008408 | 50 | 12 | 16491 | 2164 |
TOE1,EXOSC2,APEX1,ERI1,APLF,POLA1,CNOT6,EXOSC4,ERI3,NOCT,PARN,DIS3L2 |
| 2.571e-02 | -3.66 | glycerophospholipid metabolic process | biological process | GO:0006650 | 246 | 43 | 16441 | 2138 |
SERINC5,PIGM,PIGN,PAFAH1B1,LPCAT2,GPAT3,PIGH,PIK3R4,PLA2G12A,DPM3,LPCAT3,IP6K2,SYNJ1,LCLAT1,INPP1,PIP4K2A,LPIN1,PI4KB,LPIN2,PIGG,SYNJ2,CPNE7,PNPLA3,MGLL,LPCAT1,FGF2,PI4KAP2,AGPAT4,GPCPD1,PITPNB,PLCB1,PIK3CB,VAC14,TAMM41,ALG5,SERINC1,PEMT,ABHD3,ATM,GPAM,BPNT1,MTMR1,SMG1 |
| 2.576e-02 | -3.66 | PROTEIN_KINASE_ACTIVITY | MSigDB lists | PROTEIN_KINASE_ACTIVITY | 283 | 48 | 17758 | 2279 |
TNIK,TTN,BCKDK,MINK1,CLK1,TAF1,MAP3K13,PDK4,TRIO,DDR2,RIPK1,CSNK2A1,CSNK1A1,RPS6KA5,TGFBR2,MAP2K3,PRKCH,PRKCE,PRKD3,NEK6,PHKA1,GTF2H1,PXK,MET,MAP3K12,PRKACB,CLK2,RPS6KB2,SRPK2,TNK2,SIK3,CAMKK2,PDK1,CRIM1,COL4A3BP,SGK2,STK10,FGFR1,OXSR1,CDK9,IRAK2,ATM,NRP1,BRSK2,RPS6KC1,ZAK,SMG1,STK4 |
| 2.576e-02 | -3.66 | BROWNE_HCMV_INFECTION_14HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_DN | 283 | 48 | 17758 | 2279 |
MPI,MAP2K5,PRKAB2,TRIO,TRAK1,SLC25A12,FARS2,ZFP36L1,MLH1,DENND3,EEA1,ETFB,TMCO6,PRKCE,DST,SOCS1,ZKSCAN1,CEP290,STC2,SYNJ2,MET,AMOT,ETV1,SKIV2L,CRADD,FGF2,MYO10,STAMBP,MTIF2,EIF3J,MINA,PSMG1,AKAP13,TCF7L2,DKK1,SMAD3,IRS1,SPAG9,ACOX1,HIPK2,ITGA2,AHNAK2,ANXA2,HMBS,MMP16,SGSM3,GALE,NIT1 |
| 2.577e-02 | -3.66 | CSTF2 (cleavage stimulation factor, 3' pre-RNA, subunit 2) | protein interactions | 1478 | 68 | 16 | 16036 | 2270 |
CHMP2A,CUL7,KIAA1143,TTC27,BRCA1,CEP126,IKBKAP,PARN,SYMPK,CDC73,ECH1,POLR2A,SUB1,CHD3,CPSF3,PABPC1 |
| 2.577e-02 | -3.66 | GANAB (glucosidase, alpha; neutral AB) | protein interactions | 23193 | 68 | 16 | 16036 | 2270 |
GARS,CUL7,JUP,NARS,PRKCSH,SIRT7,METTL23,PTPN12,SUPT5H,CUTC,PDE3A,ISG15,RAP1A,MYC,H2AFX,TERF2 |
| 2.578e-02 | -3.66 | genital_tract-extragonadal-germ_cell_tumour-mixed | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-mixed | 29 | 8 | 17775 | 2278 |
BRAF,NRAS,KDM2A,NF1,JMJD1C,WDR26,KMT2A,RPGRIP1L |
| 2.579e-02 | -3.66 | CSA_PPIASE_1 | prosite domains | PS00170 | 19 | 6 | 11866 | 1504 |
PPIL1,RANBP2,PPID,CWC27,PPIL3,PPIL2 |
| 2.582e-02 | -3.66 | ATGGYGGA_UNKNOWN | MSigDB lists | ATGGYGGA_UNKNOWN | 93 | 19 | 17758 | 2279 |
BDNF,TUBA1A,PPP1R21,KLHL18,PBX1,POU2F1,BRCA1,TBC1D16,CSNK1A1,SYMPK,GABPB2,EXOC6,RGS17,APBB3,HOXA3,NBEA,WDR33,ZMYM2,PRPS1 |
| 2.583e-02 | -3.66 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 163 | 30 | 17758 | 2279 |
TSHZ1,SCAF11,CGN,FGF9,SERINC5,SLC40A1,TSPYL4,MED13L,MARCKSL1,ADAMTS6,ATF7IP,ARHGAP32,PTK2,TGFBR2,MLLT10,ATXN7,HELZ,CHD3,KIAA0355,HERC1,ZCCHC6,ATM,RBM26,CELF1,PREPL,ZNF397,PRKACB,PTPRK,CPT1C,KAT6A |
| 2.592e-02 | -3.65 | sarcoma | COSMIC cancer mutations | sarcoma | 57 | 13 | 17775 | 2278 |
ABL1,SRSF2,BRAF,NRAS,SUFU,JAZF1,FUS,MLH1,RUNX1,MET,KIAA1549,FGFR1,SMARCB1 |
| 2.593e-02 | -3.65 | - | gene3d domains | 1.10.220.10 | 13 | 5 | 9988 | 1398 |
ANXA5,ANXA2,ANXA7,ANXA10,ANXA1 |
| 2.597e-02 | -3.65 | BIOCARTA_VEGF_PATHWAY | MSigDB lists | BIOCARTA_VEGF_PATHWAY | 29 | 8 | 17758 | 2279 |
EIF2S2,PXN,SHC1,HIF1A,EIF2S1,PTK2,EIF2B3,PRKCA |
| 2.597e-02 | -3.65 | HORMONE_RECEPTOR_BINDING | MSigDB lists | HORMONE_RECEPTOR_BINDING | 29 | 8 | 17758 | 2279 |
NSD1,PPARGC1B,JMJD1C,MED24,SMARCD3,MED16,OASL,NRIP1 |
| 2.597e-02 | -3.65 | RAS_GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | RAS_GTPASE_ACTIVATOR_ACTIVITY | 29 | 8 | 17758 | 2279 |
CDC42EP2,NF1,OPHN1,PREX1,RANGAP1,ERRFI1,ARHGAP10,ARHGAP27 |
| 2.599e-02 | -3.65 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | 762 | 116 | 17775 | 2278 |
ZNF292,USP7,SPRED2,TRPM2,CYLD,NF1,SMARCA4,ZNF107,BCOR,ST3GAL6,HMOX2,DENND3,NOP56,SMARCB1,IDI1,JAG1,PDZD2,SOCS1,ACD,ZFHX3,TBC1D22A,PPFIBP1,FSIP2,ANKRD11,NBEA,ME1,CORO1A,KDM5C,MET,DENND1A,VPS13B,SF3A1,NARS2,FLNC,ACSL5,NRAS,KMT2D,NR6A1,KLHL23,PTPRM,CDK4,LRRC8A,MEF2D,BRCA1,ODC1,MAK16,FGFR1,RANBP2,LSM14A,HNRNPR,ASTN2,ZNF236,VPS13D,CSMD3,DNAH2,RUNX1,BRCC3,PTPN14,BRAF,CELSR1,FN1,KLC4,NHS,TRAK1,C1orf226,FAN1,OPHN1,CLSTN2,CCDC7,MLH1,QSER1,TGFBR2,GFM2,DNAH1,MFSD10,MTUS1,ABL1,SH2B3,PTPN2,GLTP,RDX,SYNJ2,POLR1B,LDLRAD3,SOX6,MYB,NOM1,CLK2,ZNF234,ZC4H2,SMARCAD1,ELOVL6,SETD2,ARHGAP39,ZBED4,RYR2,MARS,MAP7D1,PRDM1,PPIP5K2,ANKRD20A4,PIK3CB,PHF6,CENPP,PRPF40B,HERC1,SPEN,FAT1,MSH3,DNAJC12,ATM,TMEM117,APAF1,ITGB4,MAP2K4,ZSWIM6 |
| 2.599e-02 | -3.65 | acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_T_cell_leukaemia | 762 | 116 | 17775 | 2278 |
ZNF292,USP7,SPRED2,TRPM2,CYLD,NF1,SMARCA4,ZNF107,BCOR,ST3GAL6,HMOX2,DENND3,NOP56,SMARCB1,IDI1,JAG1,PDZD2,SOCS1,ACD,ZFHX3,TBC1D22A,PPFIBP1,FSIP2,ANKRD11,NBEA,ME1,CORO1A,KDM5C,MET,DENND1A,VPS13B,SF3A1,NARS2,FLNC,ACSL5,NRAS,KMT2D,NR6A1,KLHL23,PTPRM,CDK4,LRRC8A,MEF2D,BRCA1,ODC1,MAK16,FGFR1,RANBP2,LSM14A,HNRNPR,ASTN2,ZNF236,VPS13D,CSMD3,DNAH2,RUNX1,BRCC3,PTPN14,BRAF,CELSR1,FN1,KLC4,NHS,TRAK1,C1orf226,FAN1,OPHN1,CLSTN2,CCDC7,MLH1,QSER1,TGFBR2,GFM2,DNAH1,MFSD10,MTUS1,ABL1,SH2B3,PTPN2,GLTP,RDX,SYNJ2,POLR1B,LDLRAD3,SOX6,MYB,NOM1,CLK2,ZNF234,ZC4H2,SMARCAD1,ELOVL6,SETD2,ARHGAP39,ZBED4,RYR2,MARS,MAP7D1,PRDM1,PPIP5K2,ANKRD20A4,PIK3CB,PHF6,CENPP,PRPF40B,HERC1,SPEN,FAT1,MSH3,DNAJC12,ATM,TMEM117,APAF1,ITGB4,MAP2K4,ZSWIM6 |
| 2.601e-02 | -3.65 | human chr4q26 | chromosome location | human chr4q26 | 24 | 6 | 26250 | 2590 |
LOC645513,CAMK2D,SNHG8,ARSJ,FGF2,SEC24D |
| 2.601e-02 | -3.65 | human chr20q13.13 | chromosome location | human chr20q13.13 | 24 | 6 | 26250 | 2590 |
ZFAS1,ZNFX1,BCAS4,ADNP,RNF114,PREX1 |
| 2.603e-02 | -3.65 | CCT5 (chaperonin containing TCP1, subunit 5 (epsilon)) | protein interactions | 22948 | 119 | 25 | 16036 | 2270 |
CUL7,FBXW4,CUL4A,FN1,SIRT6,SIRT7,PPP2R2A,IKBKAP,SGK2,TARS,UBC,PEX7,SRSF2,AHNAK,CDK9,MYC,ATXN2,H2AFX,GPN1,RNF2,FUS,AHCYL1,IGBP1,SRRM2,RPS6KB2 |
| 2.603e-02 | -3.65 | PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR | MSigDB lists | PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR | 331 | 55 | 17758 | 2279 |
XYLB,TNIK,TTN,BCKDK,MVK,MINK1,TAF1,MAP3K13,CLK1,PDK4,TRIO,DDR2,CSNK2A1,RIPK1,TGFBR2,CSNK1A1,RPS6KA5,MAP2K3,PRKCH,PRKCE,PRKD3,PI4KB,NEK6,PHKA1,GTF2H1,MET,PXK,MAP3K12,N4BP2,PRKACB,RPS6KB2,CLK2,SRPK2,SIK3,TNK2,CAMKK2,PDK1,CRIM1,COL4A3BP,GALK2,SGK2,STK10,PIK3CB,FGFR1,OXSR1,CDK9,IRAK2,HK2,ATM,NRP1,RPS6KC1,BRSK2,ZAK,SMG1,STK4 |
| 2.607e-02 | -3.65 | - | gene3d domains | 3.30.230.10 | 22 | 7 | 9988 | 1398 |
PMS1,MVK,MLH1,GALK2,RPS16,GFM2,LONP1 |
| 2.614e-02 | -3.64 | male germ cell nucleus | cellular component | GO:0001673 | 19 | 6 | 17570 | 2233 |
RAN,MLH1,TRIP13,TERF2,H2AFX,RPA1 |
| 2.614e-02 | -3.64 | Spliceosome | KEGG pathways | ko03040 | 132 | 25 | 6908 | 881 |
SART1,PRPF38B,SNU13,PRPF31,TRA2A,PLRG1,SF3A3,PPIL1,ZMAT2,HNRNPA3,HSPA1A,HSPA1B,PRPF40B,SNW1,SRSF2,CTNNBL1,BCAS2,PHF5A,BUD31,PQBP1,NCBP2,PRPF4,HNRNPM,PRPF19,SF3A1 |
| 2.614e-02 | -3.64 | Spliceosome | KEGG pathways | hsa03040 | 132 | 25 | 6908 | 881 |
SART1,PRPF38B,SNU13,PRPF31,TRA2A,PLRG1,SF3A3,PPIL1,ZMAT2,HNRNPA3,HSPA1A,HSPA1B,PRPF40B,SNW1,SRSF2,CTNNBL1,BCAS2,PHF5A,BUD31,PQBP1,NCBP2,PRPF4,HNRNPM,PRPF19,SF3A1 |
| 2.614e-02 | -3.64 | SANSOM_APC_TARGETS | MSigDB lists | SANSOM_APC_TARGETS | 196 | 35 | 17758 | 2279 |
HMGA2,TTC27,MRI1,MED13L,RNF43,IKBKAP,SNW1,POLR3D,PVRL3,MYC,ANKRD11,MAD1L1,SHMT2,KIAA0922,CD44,CDC37,SESN2,PSAT1,MTHFD1L,AKAP13,SOX4,EIF5B,CENPP,SRCAP,SRRD,HSPBAP1,ORC5,SNX24,CBWD1,FKBP5,GALNT10,TSEN2,METTL2B,MUTYH,ANAPC4 |
| 2.614e-02 | -3.64 | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN | 196 | 35 | 17758 | 2279 |
USP7,MPI,TRIP6,URB2,SLC6A8,HDDC2,PABPC4,WNT2B,TOX4,CAD,BRE,IFIT5,KIAA0922,MAP3K12,ZMYM2,SLC25A1,FADS1,PFKFB4,RBCK1,HSPA5,GNG7,WDR18,RFX2,RYR2,RSBN1,RABAC1,GPNMB,CRYBG3,SEC31A,PWP1,CHD3,E2F4,SQLE,MTMR1,ZBTB24 |
| 2.614e-02 | -3.64 | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDM_UP | 196 | 35 | 17758 | 2279 |
XPC,SPATS2,DDIT4,MARVELD2,NCKIPSD,MAD1L1,TSPAN14,LYST,ZNF124,MPP6,WDR61,KIAA1143,CRADD,CLYBL,POLA1,TMEM216,ATG12,TTYH2,GALK2,TPRA1,SUPT5H,CPT1A,EVI5,CHCHD6,STK10,ECH1,PGD,HLA-DMA,NCOR1,HMBS,USP11,BRCC3,CATSPERG,SYNPO,DDIT3 |
| 2.614e-02 | -3.64 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 196 | 35 | 17758 | 2279 |
ADAM19,DYM,ID2,DPM3,BHLHE40,ST3GAL6,EEA1,ETFB,IQGAP2,SHC1,S100A10,MBD2,CLDND1,CD44,ITGAX,ERRFI1,PRF1,LYPLA2,SF3A1,CDK4,LGALS1,MAP7D1,PACS1,KRTCAP2,ODC1,KLF6,UBC,ANXA1,AHNAK,KLF4,RNF138,PPP3CC,ANXA2,NRP1,ZMAT3 |
| 2.614e-02 | -3.64 | GSE22886_CTRL_VS_LPS_24H_DC_UP | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_UP | 196 | 35 | 17758 | 2279 |
COMMD10,SEC24D,SLC48A1,CAMK1,NDUFB5,HSD17B10,MAP1S,WDR37,POP5,AP1B1,PABPC4,PCYOX1L,RAP1A,NDUFV1,COPS4,SUCLG2,PTGS1,PABPC1,WDR61,ANAPC13,APEX1,GPHN,RNMT,RAB7A,TBXAS1,COTL1,HLA-DMA,MSRA,PEMT,SLC16A1,FIS1,KIAA0196,NRP1,ZBTB11,HS2ST1 |
| 2.614e-02 | -3.64 | GSE27786_BCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_BCELL_VS_CD8_TCELL_UP | 196 | 35 | 17758 | 2279 |
PPHLN1,TUBE1,BTBD9,BHLHE40,DNAJC22,REEP5,HSPA1A,PAIP2,SMARCB1,ZNF326,RELB,ATP6V0D1,CEP128,ELOF1,PRIM2,ANKRD33B,PPP1R21,RDH10,ATAT1,LIG4,VIM,SON,HSPA1B,EXOC6,PEX1,SKIL,BAZ2B,SUFU,ARID3B,SLC25A19,ADAM9,SLC4A7,IFT140,TRAF3,TXN2 |
| 2.618e-02 | -3.64 | JI_RESPONSE_TO_FSH_DN | MSigDB lists | JI_RESPONSE_TO_FSH_DN | 57 | 13 | 17758 | 2279 |
DDX3X,FN1,FGF2,SNAP23,VCAN,HK2,BRCA1,PITPNB,CYB5B,PRPS1,MAT2A,SERBP1,TOP1 |
| 2.618e-02 | -3.64 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN | 57 | 13 | 17758 | 2279 |
PTCD2,GATA6,SIX5,GDPD1,FAN1,HOXA3,GSTA4,BMP4,GPAM,ZNF397,NAPEPLD,CMTM3,DHX35 |
| 2.622e-02 | -3.64 | epithelial | COSMIC cancer mutations | epithelial | 373 | 61 | 17775 | 2278 |
CGN,DNM3,BRAF,TRERF1,ARID2,NUP160,PITPNM1,AMBRA1,MAN1A1,ABCA7,DST,SNW1,PDZD2,NUP133,CEP290,NVL,THAP4,SEC24C,PDE10A,MYC,ANKRD11,RDX,AKNAD1,YARS,MAP3K12,AUP1,CARM1,TOP1,VPS13B,ARNTL2,KMT2D,RREB1,FAM111B,NOL8,ARHGAP39,C11orf80,SCFD2,RYR2,ATXN1,PEAR1,ZNFX1,RABAC1,PALLD,FGFR1,TPK1,LRP1B,AHNAK,HELZ,EHMT2,SUFU,TECPR2,DISP1,MDN1,ITGB4,PDCD11,ZBTB11,KIF1B,MMP16,DCAF5,PTPN14,TMCC1 |
| 2.625e-02 | -3.64 | lung-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | lung-carcinoma-mucoepidermoid_carcinoma | 81 | 17 | 17775 | 2278 |
NRAS,METTL23,MKS1,DSP,MFSD10,MTUS1,DST,ZFP62,DHX33,FAT1,WDR73,LTN1,TMEM99,GEMIN4,ANXA2,KMT2A,PDCD11 |
| 2.626e-02 | -3.64 | alpha-amino acid metabolic process | biological process | GO:1901605 | 253 | 44 | 16441 | 2138 |
SEPHS2,GGT1,DMGDH,SERINC5,SDSL,AUH,MRI1,SLC25A21,PLOD1,PLA2G12A,LPCAT3,SLC6A8,PHGDH,AHCYL2,CAD,GART,ASNS,PYCRL,ATIC,PHYKPL,HIBCH,SHMT2,AHCYL1,ALDH18A1,MTHFD2L,MPST,MTHFD1,PSAT1,PPAT,ALDH1L2,MTHFD1L,ODC1,DLST,MTR,PYCR1,GLS,DDAH2,MSRA,MTHFD2,SERINC1,PEMT,DPEP1,DTD1,GCSH |
| 2.629e-02 | -3.64 | auditory receptor cell differentiation | biological process | GO:0042491 | 34 | 9 | 16441 | 2138 |
JAG1,PAFAH1B1,KCNMA1,WDPCP,CUX1,MYO7A,SLC4A7,RBPJ,FGFR1 |
| 2.629e-02 | -3.64 | blood vessel remodeling | biological process | GO:0001974 | 34 | 9 | 16441 | 2138 |
DLL4,JAG1,HOXA3,SEMA3C,RBPJ,TGFB2,NOL3,FOXC1,MEF2C |
| 2.630e-02 | -3.64 | cardiac chamber development | biological process | GO:0003205 | 123 | 24 | 16441 | 2138 |
TNNC1,PTCD2,DLL4,LUZP1,ANK2,SMAD7,ID2,SMARCD3,RYR2,ARID1A,SOX4,DSP,FOXC1,FKBP1A,MSX2,JAG1,GATA6,HIF1A,TBX3,SEMA3C,BMP4,RBPJ,TPM1,MEF2C |
| 2.634e-02 | -3.64 | oxidative phosphorylation | biological process | GO:0006119 | 68 | 15 | 16441 | 2138 |
BDNF,NDUFA5,NDUFV1,COQ9,NDUFB5,SURF1,CHCHD10,NDUFS5,NDUFA6,COX10,FXN,NDUFS7,NDUFB3,SNCA,ATP5D |
| 2.640e-02 | -3.63 | ATHOOK | prints domains | PR00929 | 3 | 2 | 4759 | 462 |
HMGA2,SRCAP |
| 2.640e-02 | -3.63 | INOS145TPRIP | prints domains | PR02107 | 3 | 2 | 4759 | 462 |
ITPRIPL1,ITPRIP |
| 2.640e-02 | -3.63 | CUDAOXIDASE | prints domains | PR00766 | 3 | 2 | 4759 | 462 |
AOC3,AOC2 |
| 2.640e-02 | -3.63 | ANGIOMOTIN | prints domains | PR01807 | 3 | 2 | 4759 | 462 |
AMOTL1,AMOT |
| 2.643e-02 | -3.63 | response to radiation | biological process | GO:0009314 | 485 | 78 | 16441 | 2138 |
POLB,NF1,TMEM109,FANCD2,IKBIP,PRKCA,RPAIN,KDM1A,ABL2,ASNS,BRE,PMAIP1,PPID,XRCC2,HYAL1,KMT2A,SPIDR,OGG1,PTPRK,DEAF1,TRIM13,ATF4,EYA3,ATXN1,BRCA1,CAV1,PDE8B,BRCA2,HYAL3,ALAD,RAD18,TP53BP1,PER1,H2AFX,RAD51B,BRCC3,XRCC4,TROVE2,RBP1,BRAF,EGR1,XPC,XRRA1,ID2,BHLHE40,PITPNM1,RHBDD1,NEDD4,INTS7,TMEM161A,COPS3,MYC,TRIAP1,NDRG4,NLGN3,ANGPT2,HMGCR,CLK2,BDNF,SYNGAP1,RDH10,LIG4,IL6R,MEN1,NAPEPLD,ZRANB3,RDH11,ANXA1,CAT,GADD45A,GPC2,HIF1A,EIF2S1,FNTB,AEN,ATM,ZAK,HRH1 |
| 2.643e-02 | -3.63 | GSK3A (glycogen synthase kinase 3 alpha) | protein interactions | 2931 | 52 | 13 | 16036 | 2270 |
PRKCH,DEAF1,PRKD3,BICD1,PXN,SPG21,VTA1,MYC,MCL1,PPP3CC,PRKCA,LRSAM1,MAPT |
| 2.643e-02 | -3.63 | CDC16 (cell division cycle 16) | protein interactions | 8881 | 52 | 13 | 16036 | 2270 |
SMAD3,SKIL,ANAPC1,ANAPC13,TP53BP1,TAF3,SMARCAD1,ANAPC11,TAF4,ANAPC10,C11orf49,BRCA1,ANAPC4 |
| 2.644e-02 | -3.63 | Formation of TC-NER Pre-Incision Complex | REACTOME pathways | R-HSA-6781823 | 54 | 13 | 8202 | 1117 |
USP7,GTF2H3,CUL4A,COPS4,GTF2H2C,COPS5,COPS3,GTF2H1,COPS7B,COPS6,UBC,POLR2A,PRPF19 |
| 2.647e-02 | -3.63 | TP73 (tumor protein p73) | protein interactions | 7161 | 125 | 26 | 16036 | 2270 |
FBXO45,TNK2,DNM3,TTLL5,STAG1,DPH1,AGO2,RCHY1,BRCA1,DENND4A,KDM1A,NEDD4,SMAD3,ADH5,ABL1,TP53BP1,CCNT1,CHD3,DNAJB6,MYC,HIPK2,CEBPZ,IKBKB,FUS,IGF2BP1,N4BP2 |
| 2.647e-02 | -3.63 | SMAD9 (SMAD family member 9) | protein interactions | 4093 | 125 | 26 | 16036 | 2270 |
HMGA2,KMT2D,EIF3C,STAG1,FN1,ZNF587,RFX1,C10orf2,ZNF83,ARID1B,PELP1,KDM1A,PABPC4,DKK1,SMAD3,DST,BAZ1A,UBE3A,ZNF557,LEMD3,DNAJA3,SIL1,CTR9,PSAP,CEP135,SMG1 |
| 2.651e-02 | -3.63 | GSE3982_MAST_CELL_VS_MAC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_DN | 183 | 33 | 17758 | 2279 |
ZNF706,CELSR1,GTF2IRD1,SIRT2,TUBB6,QSER1,PLEK2,FOXO3,FDX1,ZNF804A,RNF40,ADH5,S100A10,CNIH3,MCM5,ME1,PCOLCE2,NR6A1,PHACTR2,GNL1,EIF5B,TPK1,INF2,SPAG9,NSF,UBAP1,ACOX1,MKL2,TNFRSF1A,ADAM9,FKBP5,RPS6KB1,ADK |
| 2.651e-02 | -3.63 | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP | 183 | 33 | 17758 | 2279 |
TRPM2,TNFRSF21,C16orf52,NAT10,ID2,MYNN,C1orf52,FOSL2,TNKS1BP1,LTB4R,PCDH7,JAG1,ZFYVE28,APLF,FBXO31,PPM1K,TNK2,ADAMTSL3,WDFY3,UPP1,PTPRM,PLAC8L1,C5AR1,FERMT2,DSP,SLC23A2,ASCC3,ZDHHC11,BICD1,PUS1,NRP1,RFXAP,DDIT3 |
| 2.662e-02 | -3.63 | GTGTGAG,MIR-342 | MSigDB lists | GTGTGAG,MIR-342 | 63 | 14 | 17758 | 2279 |
DDX3X,CAMKK2,DDX50,MINK1,UBN1,AGPAT4,NBEA,RPS6KB1,RSBN1,SLC6A8,RPS6KA5,ZAK,ARID1B,SOX6 |
| 2.662e-02 | -3.63 | BOYAULT_LIVER_CANCER_SUBCLASS_G6_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G6_UP | 63 | 14 | 17758 | 2279 |
FBXL5,CTNNBL1,HSDL2,CCDC53,RHOBTB1,TIMM17A,SULT4A1,VSNL1,GREB1,RNF43,BMP4,FHIT,LPIN1,TMCC1 |
| 2.662e-02 | -3.63 | PID_MYC_REPRESS_PATHWAY | MSigDB lists | PID_MYC_REPRESS_PATHWAY | 63 | 14 | 17758 | 2279 |
SMAD3,ZBTB17,GADD45A,MYC,TMEM126A,LGALS1,ID2,ZFP36L1,BRCA1,CLU,ITGB4,FOXO3,DDIT3,DKK1 |
| 2.663e-02 | -3.63 | MITSIADES_RESPONSE_TO_APLIDIN_DN | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_DN | 243 | 42 | 17758 | 2279 |
USP7,DROSHA,SLK,CSNK2A1,RCAN1,PRKCA,RSRC1,MBNL1,MFHAS1,CAD,MCAM,MCM5,MYC,SLC38A2,PDS5B,TTC3,CMPK1,LPCAT1,AKAP11,TRIP13,SERBP1,MYB,RFC4,SLC38A1,PPAT,SUMO3,ATXN1,MCM2,DSP,PIK3CB,CHAF1A,SLC7A1,EPRS,TRRAP,PALB2,HNRNPR,SPEN,TRAF3,HEATR1,MDN1,TBL1X,PRKAR2A |
| 2.663e-02 | -3.63 | V$NGFIC_01 | MSigDB lists | V$NGFIC_01 | 243 | 42 | 17758 | 2279 |
EGR1,CA11,FAM122B,IP6K2,BHLHE40,RSPRY1,FAM192A,ZNF827,KDM2A,SREBF2,VGF,STC2,RELB,SHF,ETF1,IGF2BP1,AMOT,ZMYM2,PABPC1,MYB,KDM3B,BDNF,TLE3,TPM4,ATG12,GNL1,KCNH3,SNAP25,EHBP1,AGAP1,UBTF,DAGLA,SMAD3,TSR1,AHNAK,SYNCRIP,HNRNPR,CSRNP1,RBM26,ARHGAP12,BRWD3,MEF2C |
| 2.666e-02 | -3.62 | CARBOXYLIC_ACID_TRANSPORT | MSigDB lists | CARBOXYLIC_ACID_TRANSPORT | 40 | 10 | 17758 | 2279 |
SLC3A2,SERINC1,ARL6IP5,PRAF2,SLC16A1,SLC25A12,SLC1A1,SLC16A10,SLC25A1,SLC43A1 |
| 2.666e-02 | -3.62 | chr2q32 | MSigDB lists | chr2q32 | 40 | 10 | 17758 | 2279 |
ZNF804A,GLS,WDR75,SLC40A1,SSFA2,FSIP2,DUSP19,HIBCH,DLX2,INPP1 |
| 2.666e-02 | -3.62 | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN | 40 | 10 | 17758 | 2279 |
ARHGAP21,ADAM19,CAMKK2,TRAPPC9,CUL7,TSPAN2,PHKA1,PSTPIP2,LGALS1,MTCH1 |
| 2.672e-02 | -3.62 | human chr5q23.1 | chromosome location | human chr5q23.1 | 18 | 5 | 26250 | 2590 |
COMMD10,SRFBP1,SEMA6A-AS1,SEMA6A,LVRN |
| 2.672e-02 | -3.62 | human chr3p14.1 | chromosome location | human chr3p14.1 | 18 | 5 | 26250 | 2590 |
PRICKLE2,SUCLG2,MAGI1,FOXP1,SLC25A26 |
| 2.673e-02 | -3.62 | BROMO | smart domains | SM00297 | 43 | 11 | 9131 | 1249 |
BAZ1A,ASH1L,BRD4,BAZ2B,TAF1,BAZ2A,SMARCA4,BRD9,KMT2A,BRWD3,TRIM66 |
| 2.676e-02 | -3.62 | ADF-H/Gelsolin-like_dom | interpro domains | IPR029006 | 24 | 7 | 18293 | 2341 |
SVIL,SEC24A,DBN1,COTL1,SEC24D,SEC24C,GMFB |
| 2.676e-02 | -3.62 | CATGTAA,MIR-496 | MSigDB lists | CATGTAA,MIR-496 | 170 | 31 | 17758 | 2279 |
ZCCHC14,TTN,BDNF,PAFAH1B1,KHDRBS1,B4GALT5,SETD2,USP42,SATB2,RSBN1,PRDM1,BRCA1,LENG8,PRPF39,ZMAT2,UBR5,SEMA6A,PDE3A,MAT2A,CHD7,DDX3X,HNRNPR,LEMD3,TECPR2,TAF4,NBEA,ZMYM2,MEF2C,ZNF507,NAV3,TMEM33 |
| 2.676e-02 | -3.62 | YAMAZAKI_TCEB3_TARGETS_UP | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_UP | 170 | 31 | 17758 | 2279 |
PRPF38B,LAMC1,SLC38A1,PTPRM,MFGE8,TFPI,HSPA5,PLOD1,ID2,COBLL1,GRINA,MBNL2,USP46,SEMA6A,HERPUD1,FDX1,TCF7L2,WARS,SRPRB,SLC7A1,RSPRY1,PXDN,GATA6,ZFHX3,SLC16A1,ANXA2,PSAP,CLU,SERPINH1,NR2F2,LPP |
| 2.676e-02 | -3.62 | VERHAAK_GLIOBLASTOMA_PRONEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_PRONEURAL | 170 | 31 | 17758 | 2279 |
DBN1,FGF9,GPM6A,DNM3,MCM10,MYO10,ZNF821,ZC4H2,ATAT1,MARCKSL1,CAMSAP2,BCOR,SOX4,SLC1A1,KDM1A,ZNF804A,CHD7,FBXO21,RNFT2,ATAD5,PDE10A,SLCO5A1,GSTA4,TTC3,NLGN3,RBPJ,MMP16,MAPT,HN1,MYB,TMCC1 |
| 2.676e-02 | -3.62 | GROSS_HYPOXIA_VIA_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_UP | 75 | 16 | 17758 | 2279 |
ACSL5,SRM,USP42,H2AFJ,NOP58,BZW2,USP46,MAT2A,FRRS1,NOP56,MGAT2,TSR1,GART,PPID,SHMT2,TNRC6A |
| 2.676e-02 | -3.62 | RADMACHER_AML_PROGNOSIS | MSigDB lists | RADMACHER_AML_PROGNOSIS | 75 | 16 | 17758 | 2279 |
MSI2,SKAP2,FOXO1,SLC2A1,TBXAS1,PIK3R4,SEMA3F,SLC6A8,FGFR1,PLIN2,PXDN,PMEPA1,NFKBIB,NR2F2,TMEM158,SMG1 |
| 2.680e-02 | -3.62 | MORF_ORC1L | MSigDB lists | MORF_ORC1L | 69 | 15 | 17758 | 2279 |
SIK3,TNK2,MVK,TAF1,PRKCSH,LSM12,FAM189B,XRCC2,RAP1GAP2,PSMA1,PITPNM1,TOMM34,POLR2A,ARIH2,ARPC3 |
| 2.682e-02 | -3.62 | V$RREB1_01 | MSigDB lists | V$RREB1_01 | 203 | 36 | 17758 | 2279 |
CYLD,DLL4,TRERF1,PRKCE,NOVA2,GLYR1,IGF2BP1,ADCK4,S100A14,AHCYL1,CDK12,FLNC,HMBOX1,FMNL3,BDNF,ZNF821,ATG12,TOR1AIP2,VIM,KRTCAP2,C8orf33,PLCB1,UBE2E1,S100A16,NCDN,RERE,MLLT10,C1orf122,ADNP,HNRNPR,LUC7L3,INTS9,HOXA3,RUNX1,BRWD3,ZNF532 |
| 2.682e-02 | -3.62 | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 203 | 36 | 17758 | 2279 |
TNIK,TTN,BCKDK,MINK1,CLK1,TAF1,MAP3K13,TRIO,RIPK1,CSNK2A1,CSNK1A1,RPS6KA5,TGFBR2,PRKCH,PRKCE,PRKD3,NEK6,PHKA1,GTF2H1,MAP3K12,PRKACB,CLK2,RPS6KB2,SRPK2,SIK3,SGK2,STK10,OXSR1,CDK9,IRAK2,ATM,RPS6KC1,BRSK2,ZAK,SMG1,STK4 |
| 2.683e-02 | -3.62 | - | gene3d domains | 1.10.1540.10 | 9 | 4 | 9988 | 1398 |
NBEA,NBEAL1,WDFY3,LYST |
| 2.686e-02 | -3.62 | FUS (FUS RNA binding protein) | protein interactions | 2521 | 320 | 58 | 16036 | 2270 |
CUL7,CUL4A,FN1,MFGE8,SIRT7,NKD2,SF3A3,PHGDH,SAFB2,HNRNPA3,ABL1,SRSF2,ARMC6,PYCRL,UBAP2L,ANXA5,HARS2,UPF2,SSBP1,RAN,AMOT,ZMYM2,TOMM34,SERBP1,TIMM50,SF3A1,MTHFD1,RPS6KB2,FAM98A,PTBP2,TUBA1A,LSM12,PSPC1,RAB7A,ABCF2,HSPA5,BCS1L,LDHA,MEF2D,SAP30BP,TARS,TCF7L2,MAT2A,POLR2A,UBC,RAD54B,RPA1,PYCR1,DYNC1H1,HPRT1,UBAP2,SYNCRIP,COPS5,CUL2,TBPL1,FUS,COPS6,BMI1 |
| 2.686e-02 | -3.62 | large_intestine-colon-carcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma | 2718 | 380 | 17775 | 2278 |
MYCBP2,CGN,DPH1,AARS2,SBF2,AARS,AMBRA1,TOM1L1,PCDH7,PDZD2,ZFHX3,NSRP1,AP1M1,MEIS3,SEH1L,CSGALNACT2,NRAS,UPP1,CUX1,MSRB3,C10orf76,SON,SLC9A5,GZF1,GNAI1,OSBPL1A,AHNAK,BRCA2,TRRAP,HIC2,VPS13D,SEMA3C,DNAH2,RUNX1,SPOCK3,ZNF532,CARS,HERC2,EP400,C9orf78,CELSR1,ANKRD17,LARS2,PRPF31,SIRT7,DLGAP4,PIK3R4,BTBD9,CCDC47,RSF1,TGFBR2,C1orf50,ABCA7,SLC39A11,TECTA,NAV1,PI4KB,TSPAN2,SLC38A5,SCAF1,CALN1,AGL,ANGPT2,NOM1,HMGCR,ADARB1,SCAF11,SIK3,DDX28,STAG1,AOC2,RAPGEF4,CPT1A,EHBP1,ARIH2,NCDN,DAGLA,DYNC1H1,ZNF425,EPRS,LRP1B,TASP1,KIDINS220,CLASRP,LEMD3,SPEN,ZZEF1,ZCCHC6,DPEP1,NCOR1,ARHGAP10,HS2ST1,RTTN,SYT17,TRPM2,TRERF1,NPAS2,RIBC2,C16orf45,NDUFB5,DDR2,MYH9,ISG20L2,TUBB6,PTPRG,AP1B1,SLC25A44,LCLAT1,SAFB2,IGSF1,PAIP2,PHC2,PRKD3,ZNF827,SLX4,PUS3,ARMC6,ABCA12,TBC1D22A,ZKSCAN1,CLCN6,TTC3,PNPLA4,KMT2A,PLEKHA4,LYST,BRD4,GON4L,MTIF2,WDPCP,SATB2,PNN,DSP,TBC1D16,BAZ1A,CDC16,HOXA3,IFT140,MDN1,ANKS1A,LAMA5,YEATS2,CATSPERG,BAG1,BRAF,CA11,UTP14A,C10orf2,FARS2,ATG2B,IP6K2,MLH1,MON2,OPA1,ZNF691,GIGYF2,NEDD4,ABL1,ZNF483,NISCH,SDCBP2,LTN1,COPS7B,PLEKHG4,SAMD4A,SPTAN1,NAV3,DIS3L2,CLK2,FAM120B,DDHD1,TSHZ1,TTLL5,ARHGAP39,ADSL,PACS1,PPIP5K2,GUF1,DDX49,SLC23A2,RPA1,NSD1,SRCAP,BAZ2B,PLPPR2,AEN,SVIL,NUDT22,CORO2B,IPO4,PHF3,ATRX,NF1,GPBP1L1,POLR1A,FANCD2,TRPM6,RNF43,BCOR,SNAPC4,FRRS1,AHCYL2,ZNF804A,DST,ECM1,ZNHIT6,HKR1,MYH3,UBAP2L,ZEB1,POLR3B,SLC27A5,LONP1,VPS13B,DSC3,TNK2,SLC3A2,GCNT2,SKAP2,PPARG,SKIV2L2,MED27,NOL6,LAMA2,KMT2C,CRYBG3,CCDC28B,KIF16B,BSN,MSRA,TMCO1,GATA6,TOM1L2,CHD3,PER1,CTAGE5,CSMD3,ABCC3,ASB3,MAGI1,ZNF397,CTU2,RELL2,RHOBTB1,SEC24D,LRRC28,VTA1,MAPK8IP3,ZIC2,EVPL,ARID1B,RHBDD1,SIPA1L3,MCAM,ABCA5,MBD2,PNPLA3,HSD17B14,RANBP6,TRAPPC9,PDE4A,USP49,ELOVL6,JMJD1C,SETD2,ZFP14,LIG4,SUPT5H,CORIN,C19orf70,ISG15,VAC14,NR2F1,PRPF40B,GRIK4,SPAG9,FAM135A,PALB2,KIAA0355,INTS5,HK2,CDKAL1,ZFP90,NAPA,TBCK,PDE9A,N4BP2L2,DMXL2,ARID2,CELSR3,SLC2A1,SMARCA4,TMEM177,ARSJ,DENND3,PPP1R9A,RIOK2,CAD,VPS18,NRF1,UBR1,GRIN2C,CBR4,PPFIBP1,C15orf40,CCDC40,BCAP29,CORO1A,ADCK4,MET,AHCYL1,VCL,TSPAN14,PRMT3,SOBP,KDM3B,ARHGAP17,PHLDB2,EVL,COL5A2,PTBP2,PARP2,ATXN1,AKAP13,UBR4,EIF3H,TJAP1,WARS,RANBP2,RBBP8,SIX5,CEBPZ,PRRT3,NFASC,ZNF18,AP2S1,PARD3,BCKDK,C17orf80,MAP3K13,SUPT6H,RFX1,DYM,KLC4,CLSTN2,MED18,ENOX1,FOXP1,SFI1,SACS,ANXA7,SEC24C,IFIT5,CPNE7,LDLRAD3,HSD17B12,KDM6B,SLC6A16,ARNTL2,ADAMTSL3,LRRIQ1,PSPC1,TOP3A,FERMT2,SCMH1,MARS,ARHGEF12,TARS,POLR3A,RERE,WDR35,L3MBTL3,USP20,RBM26,MBD6,POLR1C,MMP16,SLC16A10,LMBRD2,HRH1 |
| 2.687e-02 | -3.62 | ACTA2 (actin, alpha 2, smooth muscle, aorta) | protein interactions | 59 | 85 | 19 | 16036 | 2270 |
MINK1,KCNMA1,MYH9,AARS,TMSB4X,RPA1,NOP56,RPS16,YIPF2,FSCN1,UBAP1,COPS5,CUL2,DUSP19,ICE2,TPM1,ZMAT3,PNMA1,SPTAN1 |
| 2.687e-02 | -3.62 | HHV8GK18_gp81 (ORF73) | protein interactions | 4961527 | 85 | 19 | 16036 | 2270 |
USP7,RELL2,POLB,ID1,APEX1,RBM19,ZMAT2,REEP5,UBC,RPA1,NRF1,ERI1,ZRANB2,RBPJ,PRMT5,HCFC2,PRMT3,SERBP1,CARM1 |
| 2.688e-02 | -3.62 | activating transcription factor binding | molecular function | GO:0033613 | 56 | 13 | 16491 | 2164 |
SMAD3,ZNF516,TP53BP1,PPARG,DHX33,PRDM16,HIPK2,TBX3,MEF2D,NCOR1,BHLHE40,MAD2L2,MEF2C |
| 2.689e-02 | -3.62 | positive regulation of meiotic cell cycle | biological process | GO:0051446 | 14 | 5 | 16441 | 2138 |
MSX2,MSX1,SIRT2,PLCB1,DMRT1 |
| 2.689e-02 | -3.62 | histone mRNA catabolic process | biological process | GO:0071044 | 14 | 5 | 16441 | 2138 |
ATM,EXOSC4,PAPD4,ERI1,ZCCHC6 |
| 2.689e-02 | -3.62 | pyrimidine nucleoside monophosphate metabolic process | biological process | GO:0009129 | 14 | 5 | 16441 | 2138 |
CAD,UMPS,CMPK1,NT5M,UPP1 |
| 2.689e-02 | -3.62 | CDP-diacylglycerol metabolic process | biological process | GO:0046341 | 14 | 5 | 16441 | 2138 |
TAMM41,GPAM,LCLAT1,AGPAT4,GPAT3 |
| 2.689e-02 | -3.62 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway | biological process | GO:0039531 | 14 | 5 | 16441 | 2138 |
TKFC,TRIM15,DDX60,ANKRD17,BIRC2 |
| 2.689e-02 | -3.62 | regulation of histone H3-K9 methylation | biological process | GO:0051570 | 14 | 5 | 16441 | 2138 |
BRCA1,SETD7,KDM1A,MYB,SMARCB1 |
| 2.689e-02 | -3.62 | nucleotide salvage | biological process | GO:0043173 | 14 | 5 | 16441 | 2138 |
APRT,HPRT1,AMPD3,ADK,UPP1 |
| 2.696e-02 | -3.61 | Cyclophilin-type_PPIase_CS | interpro domains | IPR020892 | 19 | 6 | 18293 | 2341 |
PPIL1,RANBP2,PPID,CWC27,PPIL3,PPIL2 |
| 2.696e-02 | -3.61 | PDEase | interpro domains | IPR023088 | 19 | 6 | 18293 | 2341 |
PDE2A,PDE4A,PDE9A,PDE10A,PDE4B,PDE8B |
| 2.701e-02 | -3.61 | AAA_8 | pfam domains | PF12780 | 14 | 5 | 16629 | 2165 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 2.705e-02 | -3.61 | LAM_G_DOMAIN | prosite domains | PS50025 | 35 | 9 | 11866 | 1504 |
LAMA4,CELSR1,CELSR3,CNTNAP3,FAT1,GAS6,LAMA2,CNTNAP3B,LAMA5 |
| 2.713e-02 | -3.61 | GCM_FANCL | MSigDB lists | GCM_FANCL | 24 | 7 | 17758 | 2279 |
IKBKAP,ANKRD17,ZMYM2,LUC7L3,DMTF1,ZNF655,ZFP14 |
| 2.713e-02 | -3.61 | SHI_SPARC_TARGETS_UP | MSigDB lists | SHI_SPARC_TARGETS_UP | 24 | 7 | 17758 | 2279 |
MRRF,ABL2,SEMA3C,TGFBR2,SEMA6A,DDIT3,ANKRD11 |
| 2.713e-02 | -3.61 | XU_CREBBP_TARGETS_UP | MSigDB lists | XU_CREBBP_TARGETS_UP | 24 | 7 | 17758 | 2279 |
ADSL,HLTF,LMBR1L,MCM2,TSTA3,NVL,GNL3 |
| 2.715e-02 | -3.61 | FAM170A (family with sequence similarity 170, member A) | protein interactions | 340069 | 13 | 5 | 16036 | 2270 |
USP7,VAPB,ZNF358,QSER1,CSNK1A1 |
| 2.715e-02 | -3.61 | KRIT1 (KRIT1, ankyrin repeat containing) | protein interactions | 889 | 13 | 5 | 16036 | 2270 |
RCHY1,RAP1A,PLCB1,RAP1B,PIK3R4 |
| 2.715e-02 | -3.61 | KLHL18 (kelch-like family member 18) | protein interactions | 23276 | 13 | 5 | 16036 | 2270 |
COPS6,COPS4,COPS5,COPS3,PCMT1 |
| 2.715e-02 | -3.61 | C4BPB (complement component 4 binding protein, beta) | protein interactions | 725 | 13 | 5 | 16036 | 2270 |
VPS52,DCTN3,FAM127A,ZNF655,DCTN4 |
| 2.715e-02 | -3.61 | FABP4 (fatty acid binding protein 4, adipocyte) | protein interactions | 2167 | 13 | 5 | 16036 | 2270 |
ACP1,TNK2,VIM,CHD3,USP15 |
| 2.715e-02 | -3.61 | STK36 (serine/threonine kinase 36) | protein interactions | 27148 | 13 | 5 | 16036 | 2270 |
SUFU,ARMC6,CDK9,MID1,CDC37 |
| 2.715e-02 | -3.61 | H3F3C (H3 histone, family 3C) | protein interactions | 440093 | 13 | 5 | 16036 | 2270 |
KDM4B,PRMT5,SMYD3,KDM1A,KAT6A |
| 2.715e-02 | -3.61 | A1BG (alpha-1-B glycoprotein) | protein interactions | 1 | 13 | 5 | 16036 | 2270 |
SHMT2,SETD7,ANXA7,GDPD1,SNCA |
| 2.715e-02 | -3.61 | BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2) | protein interactions | 60468 | 13 | 5 | 16036 | 2270 |
NCOR2,COPS6,FOSL2,DDIT3,BATF3 |
| 2.715e-02 | -3.61 | ALDH9A1 (aldehyde dehydrogenase 9 family, member A1) | protein interactions | 223 | 13 | 5 | 16036 | 2270 |
BCCIP,BRCA1,USP46,CIAPIN1,PGD |
| 2.715e-02 | -3.61 | AHCTF1 (AT hook containing transcription factor 1) | protein interactions | 25909 | 13 | 5 | 16036 | 2270 |
VAPB,SHMT2,NUP160,NUP133,SIRT7 |
| 2.715e-02 | -3.61 | CSN1S1 (casein alpha s1) | protein interactions | 1446 | 13 | 5 | 16036 | 2270 |
CSNK2A1,CUL4A,COPS5,HTRA2,STK4 |
| 2.715e-02 | -3.61 | DYNLL1 (dynein, light chain, LC8-type 1) | protein interactions | 8655 | 137 | 28 | 16036 | 2270 |
DNM3,GPHN,ACTG1,MYO10,PAFAH1B1,LDHA,DLG4,WWC1,VIM,CSNK1A1,INPP1,FKBP3,MTR,AMBRA1,DYNC1H1,DYRK1B,DDX3X,NRF1,CACNB1,NEK6,ZNF354A,TP53BP1,AMOT,BMI1,PABPC1,PKIB,PARD3,PRKACB |
| 2.726e-02 | -3.60 | Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | REACTOME pathways | R-HSA-141405 | 18 | 6 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 2.726e-02 | -3.60 | Inactivation of APC/C via direct inhibition of the APC/C complex | REACTOME pathways | R-HSA-141430 | 18 | 6 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 2.726e-02 | -3.60 | cGMP effects | REACTOME pathways | R-HSA-418457 | 18 | 6 | 8202 | 1117 |
PDE2A,PDE3B,PDE10A,PDE9A,KCNMA1,PDE3A |
| 2.727e-02 | -3.60 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | 106 | 21 | 17758 | 2279 |
PTP4A1,CDCP1,CDC42EP2,LUZP1,LIMA1,AGPAT4,CAV1,TUBB6,PLEK2,ARRDC4,NEDD4,OXSR1,ASCC3,HIF1A,PTGS1,WDR66,PERP,ANGPT2,PKNOX1,RPS6KB2,USP15 |
| 2.728e-02 | -3.60 | GSE30083_SP1_VS_SP3_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP3_THYMOCYTE_UP | 190 | 34 | 17758 | 2279 |
SLC37A3,CYP24A1,EIF3C,WDR74,NAT10,COBLL1,NECAP1,UBTD2,PIP4K2A,NEDD4,MRPS30,VPS18,TTLL11,ZNF608,VPS72,TRIAP1,HSD17B12,SLC3A2,APEX1,LAMC1,TUBA1A,ZNF821,TFPI,NUDT15,TCF7L2,TPK1,CAMK2D,ADAM9,RNF130,NFKBIB,TXN2,N4BP2L2,IPO4,PKIB |
| 2.728e-02 | -3.60 | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | 190 | 34 | 17758 | 2279 |
SLC37A3,GGT1,FEZ2,JUP,SIRT7,CERS5,KLHL18,WDR26,SYNJ1,REEP5,BIRC2,FAM49A,MFHAS1,FKBP1A,SLX4,SETD5,RELB,CORO1A,MAP3K14,CCDC88C,LYPLA2,PEA15,ATG9A,ARID5B,ZMYM5,RERE,TTC38,CHD3,TNFRSF1A,TRAF3,TBL1X,MMP16,XPO6,RNF114 |
| 2.728e-02 | -3.60 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | 190 | 34 | 17758 | 2279 |
MIF4GD,SBF2,AP1B1,FOXO3,LPIN1,PRKCH,RPP30,SUB1,PHKA1,VAPB,PCK2,PKNOX1,ANGPT2,MCEE,PDK1,TSN,ATOX1,WDHD1,POU2F1,IL6R,ZDHHC14,TPRA1,RERE,MLLT10,CHAF1A,IFT81,VPS13C,ACOX1,ASB3,NRP1,MTMR1,PKIB,MEF2C,TMEM141 |
| 2.728e-02 | -3.60 | GSE3982_DC_VS_TH1_DN | MSigDB lists | GSE3982_DC_VS_TH1_DN | 190 | 34 | 17758 | 2279 |
THOC5,ADAM19,CHST11,CYLD,LETM1,RNASEH2B,COX10,NAMPT,CHN1,YLPM1,PMAIP1,STC2,KDELC1,ZNF142,HIRIP3,ZEB1,RAN,PERP,SF3A1,FAM184A,MYB,PRPF19,RBCK1,HARS,ABCC2,KLF6,SLC39A14,VDR,ARL4A,FAM206A,FTSJ1,SQLE,SMYD3,TESC |
| 2.728e-02 | -3.60 | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_UP | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_UP | 190 | 34 | 17758 | 2279 |
DNAJC2,SHQ1,TRIP6,UTP14A,MLH1,FDX1,LPIN1,MRPS11,EIF2S2,ATP5G2,NUP133,TRIAP1,GPATCH1,GTF3C3,MICAL3,ARNTL2,WDR61,PDE4A,FAM172A,STAG1,APEX1,HARS,AGPAT4,TMEM126B,ATOX1,SLC35D1,PGD,PALB2,SRD5A3,RRAGA,ACP1,ABCC3,BRCC3,KDM4C |
| 2.728e-02 | -3.60 | GSE7852_THYMUS_VS_FAT_TREG_UP | MSigDB lists | GSE7852_THYMUS_VS_FAT_TREG_UP | 190 | 34 | 17758 | 2279 |
RWDD1,CELSR1,ST6GAL1,PPHLN1,CHCHD10,PDCD7,EDC3,ADH5,NUBPL,BCAS2,PSMG4,HCFC2,N4BP2,RABEPK,EVL,KIAA1143,SMARCAD1,SFXN4,ANKMY2,BCS1L,DCUN1D5,GUF1,TTC28,EXOC6,POLR3G,HPRT1,TRIB3,IREB2,CDC16,LUC7L3,METTL6,WDR73,PPIL3,NIT1 |
| 2.728e-02 | -3.60 | GSE17721_CTRL_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_12H_BMDM_UP | 190 | 34 | 17758 | 2279 |
SLC37A3,HM13,SSBP2,PAG1,NDUFB3,CEP164,UBR1,GPR87,METTL8,NDRG4,SOCS6,SYNJ2,MCEE,VPS37A,ZNF124,LIMA1,ELOVL6,WDPCP,GALK2,PDE2A,CPT1A,MLLT10,VDR,SUPT4H1,NME7,HELZ,FDPS,SVIL,ATM,FIS1,ABCC3,ADK,TXN2,ECHDC1 |
| 2.728e-02 | -3.60 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 190 | 34 | 17758 | 2279 |
SLC12A7,PTCD2,ADAM19,PRKCSH,TRIO,LAMTOR3,APRT,TUBB6,HLTF,REEP5,SLC25A20,FKBP1A,PEX7,SHC1,NEK6,ZFHX3,ANXA5,MRPL21,PABPC1,IFNGR2,TSTA3,GALK2,EDEM2,ODC1,UBE2E1,HLA-DMA,RPL28,TNFRSF1A,DTD1,SCARB1,BMP4,PSAP,PKIB,COG5 |
| 2.728e-02 | -3.60 | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN | 190 | 34 | 17758 | 2279 |
EGR1,FOXO1,ST6GAL1,HECTD3,APRT,C1orf52,PRKCA,ARID1B,GIT2,PIP4K2A,PAG1,MRPS30,BLOC1S2,SKI,ABL2,DECR1,ATIC,KDELC1,ETF1,AVEN,WDR61,TOR1AIP2,SLC26A11,CLNS1A,KPNA1,INSIG1,PDLIM1,INTS5,CUL2,ZNF81,TBL1X,SYNPO,IPO4,STK4 |
| 2.728e-02 | -3.60 | human chr7q34-q35 | chromosome location | human chr7q34-q35 | 3 | 2 | 26250 | 2590 |
TPK1,TBXAS1 |
| 2.728e-02 | -3.60 | human chr13q11-q12 | chromosome location | human chr13q11-q12 | 3 | 2 | 26250 | 2590 |
FGF9,ZMYM2 |
| 2.728e-02 | -3.60 | human chr3q22.2 | chromosome location | human chr3q22.2 | 3 | 2 | 26250 | 2590 |
CEP63,ANAPC13 |
| 2.730e-02 | -3.60 | TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER | MSigDB lists | TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER | 19 | 6 | 17758 | 2279 |
ZNF76,BRCA1,SNAPC4,TROVE2,SNAPC5,POLR3G |
| 2.730e-02 | -3.60 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | MSigDB lists | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | 19 | 6 | 17758 | 2279 |
EXOC1,SNAP25,STX1A,EXOC4,EXOC6,SLC30A7 |
| 2.730e-02 | -3.60 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN | 19 | 6 | 17758 | 2279 |
ZNF827,ZNF18,GEMIN4,LPCAT1,B4GALT5,CCDC85B |
| 2.730e-02 | -3.60 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN | 19 | 6 | 17758 | 2279 |
XRCC4,CDK9,MYC,CDK4,TCF3,CDC37 |
| 2.730e-02 | -3.60 | OUYANG_PROSTATE_CANCER_PROGRESSION_DN | MSigDB lists | OUYANG_PROSTATE_CANCER_PROGRESSION_DN | 19 | 6 | 17758 | 2279 |
ARFIP2,TRIB3,DIRAS1,ARL4A,MAP2K3,MAPK8IP3 |
| 2.730e-02 | -3.60 | ZHANG_RESPONSE_TO_CANTHARIDIN_UP | MSigDB lists | ZHANG_RESPONSE_TO_CANTHARIDIN_UP | 19 | 6 | 17758 | 2279 |
TRAF3,IFRD1,TRIM13,TGFBR2,PMAIP1,NAMPT |
| 2.730e-02 | -3.60 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B | MSigDB lists | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B | 19 | 6 | 17758 | 2279 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 2.730e-02 | -3.60 | MYOFIBRIL | MSigDB lists | MYOFIBRIL | 19 | 6 | 17758 | 2279 |
TNNC1,SVIL,TTN,TPM1,VCL,TPM4 |
| 2.730e-02 | -3.60 | RHO_GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | RHO_GTPASE_ACTIVATOR_ACTIVITY | 19 | 6 | 17758 | 2279 |
ERRFI1,CDC42EP2,ARHGAP10,ARHGAP27,OPHN1,PREX1 |
| 2.732e-02 | -3.60 | NS1 Mediated Effects on Host Pathways | REACTOME pathways | R-HSA-168276 | 38 | 10 | 8202 | 1117 |
RANBP2,KPNA1,KPNA3,NUP133,NUP43,NUP160,NUP214,ISG15,POM121,SEH1L |
| 2.732e-02 | -3.60 | DNA Damage Recognition in GG-NER | REACTOME pathways | R-HSA-5696394 | 38 | 10 | 8202 | 1117 |
CUL4A,COPS4,XPC,PARP2,COPS5,COPS3,COPS7B,NFRKB,COPS6,UBC |
| 2.732e-02 | -3.60 | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN | MSigDB lists | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN | 125 | 24 | 17758 | 2279 |
SARS,NOSTRIN,IFRD1,GARS,SESN2,ATF4,PSAT1,GLTSCR2,AARS,HERPUD1,PDE8B,PYCR1,ZFP62,EPRS,TRIB3,AMPD3,TCF7L1,MTHFD2,MACROD1,CCNB1IP1,IGBP1,SNAPC5,BAG1,DDIT3 |
| 2.737e-02 | -3.60 | NSFL1C (NSFL1 (p97) cofactor (p47)) | protein interactions | 55968 | 63 | 15 | 16036 | 2270 |
HIF1A,NF1,UBR1,ITPA,ATIC,SLK,UBXN1,CUL2,C11orf54,TATDN1,PRMT5,GMDS,SRP14,HSPA1A,UBC |
| 2.737e-02 | -3.60 | AHNAK (AHNAK nucleoprotein) | protein interactions | 79026 | 63 | 15 | 16036 | 2270 |
CUL7,AHNAK,ASNS,FN1,S100A10,FMNL1,SIRT7,VARS,SEC16A,YARS,XRCC4,TARS,FLNB,ISG15,RPA1 |
| 2.737e-02 | -3.60 | PKN1 (protein kinase N1) | protein interactions | 5585 | 63 | 15 | 16036 | 2270 |
ARHGAP26,PDK1,TUBA1A,MYC,CCDC85B,WBSCR22,VIM,TBXA2R,CD44,KMT2A,MID1,ARHGAP10,MAP2K3,MAPT,TOM1L1 |
| 2.739e-02 | -3.60 | RHOA (ras homolog family member A) | protein interactions | 387 | 143 | 29 | 16036 | 2270 |
ARHGAP26,SPRED2,PRDX6,TRIP6,TRIO,OPHN1,SLC25A12,RAP1GDS1,ARHGEF12,CAV1,RABAC1,ARHGAP32,AKAP13,PRKCA,CPT1A,BIRC2,HSPA1A,PITPNM1,PLXNB1,UBC,CLNS1A,ARHGAP21,TNFRSF1A,MPV17,SHMT2,ARHGAP1,TBXA2R,ARHGAP10,CASP10 |
| 2.741e-02 | -3.60 | OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) | protein interactions | 55611 | 74 | 17 | 16036 | 2270 |
DDX24,STAMBP,NAT10,CSNK2A1,BIRC2,KDM1A,UBC,ANXA1,SMAD3,ANXA7,H2AFX,TRAF3,RNF2,CPNE7,FUS,SERBP1,USP15 |
| 2.746e-02 | -3.59 | V$AP1_Q4 | MSigDB lists | V$AP1_Q4 | 257 | 44 | 17758 | 2279 |
TCF12,RELL2,RTN4,AKT1S1,TGFBR2,LCLAT1,ATXN7L1,MMP7,UBE3A,NEK6,CCDC50,ANXA7,FAM184A,SRPK2,PPP1R9B,NRAS,LAMC1,BAZ2A,TEX19,RB1CC1,WDFY3,EIF3J,RAP1GAP2,ATXN1,C11orf49,ZNFX1,VIM,PRDM1,ARRDC4,KCNH2,SLC9A5,STOML2,GNAI1,YIF1A,VDR,LRP1B,POLR3E,ZNF436,NFRKB,BLMH,RABEP1,SYNPO,ATXN7L2,LPP |
| 2.750e-02 | -3.59 | TCEB1 (transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)) | protein interactions | 6921 | 108 | 23 | 16036 | 2270 |
PRAME,APEX1,TCEB3,LAGE3,ARID1B,ARIH2,POP1,MYBBP1A,COPS4,SOCS1,HIF1A,COPS3,COPS5,CUL2,SOCS4,SOCS6,XPNPEP1,ARHGAP1,ASB3,FUS,COPS6,KMT2A,LRRC41 |
| 2.750e-02 | -3.59 | HNRNPUL1 (heterogeneous nuclear ribonucleoprotein U-like 1) | protein interactions | 11100 | 108 | 23 | 16036 | 2270 |
DBN1,CUL7,CUL4A,APEX1,SIRT7,HSPA5,MAPK1IP1L,MARS,PPIL1,SAFB2,GIT2,ECH1,NEDD4,RPA1,HNRNPH3,COPS5,CUL2,ATRIP,ATM,RNF2,COPS6,PEG10,POLR1E |
| 2.757e-02 | -3.59 | internal peptidyl-lysine acetylation | biological process | GO:0018393 | 111 | 22 | 16441 | 2138 |
KAT8,WDR75,EP400,BRD4,TRIM16,TAF1,TCF3,ELP3,ATAT1,CHD5,TADA3,SRCAP,TRRAP,BRCA2,KANSL1,PER1,MED24,POLE3,TAF12,KMT2A,YEATS2,KAT6A |
| 2.759e-02 | -3.59 | ARFIP1 (ADP-ribosylation factor interacting protein 1) | protein interactions | 27236 | 47 | 12 | 16036 | 2270 |
SEC24A,SARS,GART,TSTA3,SEC24D,G6PD,ATOX1,ARFIP2,SHMT2,PRMT3,ECH1,FLNB |
| 2.759e-02 | -3.59 | AARSD1 (alanyl-tRNA synthetase domain containing 1) | protein interactions | 80755 | 47 | 12 | 16036 | 2270 |
SRM,TTC1,TPD52L2,TUBA1A,HARS,XPO5,SERPINH1,TRMT10A,TARS,SBDS,SH3GL1,RPA1 |
| 2.759e-02 | -3.59 | NRDC (nardilysin convertase) | protein interactions | 4898 | 47 | 12 | 16036 | 2270 |
NCOR2,P3H1,KPNA3,XPO5,TSN,MAD1L1,PPP2R2A,COBLL1,PUS1,TBL1X,NCOR1,YARS |
| 2.759e-02 | -3.59 | - | gene3d domains | 4.10.1000.10 | 32 | 9 | 9988 | 1398 |
HELZ,RBM26,ZFP36L1,ZC3H8,MBNL2,ZC3H3,MBNL1,DHX57,ZC3H13 |
| 2.764e-02 | -3.59 | ZBTB46 (zinc finger and BTB domain containing 46) | protein interactions | 140685 | 22 | 7 | 16036 | 2270 |
DESI1,WIZ,GATAD2B,FBXO21,SUFU,EHMT2,EHMT1 |
| 2.764e-02 | -3.59 | CPSF3L (cleavage and polyadenylation specific factor 3-like) | protein interactions | 54973 | 22 | 7 | 16036 | 2270 |
CBWD1,ANXA7,INTS7,INTS5,TRIP13,POLR2A,INTS9 |
| 2.764e-02 | -3.59 | MYO1B (myosin IB) | protein interactions | 4430 | 22 | 7 | 16036 | 2270 |
CSNK2A1,CUL7,MYC,TCF3,SIRT7,EIF4A2,RPA1 |
| 2.764e-02 | -3.59 | TRIO (trio Rho guanine nucleotide exchange factor) | protein interactions | 7204 | 22 | 7 | 16036 | 2270 |
EXOC1,PTK2,NAV1,BCAS2,SSU72,BLMH,NAV3 |
| 2.764e-02 | -3.59 | KNSTRN (kinetochore-localized astrin/SPAG5 binding protein) | protein interactions | 90417 | 22 | 7 | 16036 | 2270 |
SHMT2,MPP6,IFT57,CLU,HSPA1A,CEP170,PRPF19 |
| 2.764e-02 | -3.59 | KLHL13 (kelch-like family member 13) | protein interactions | 90293 | 22 | 7 | 16036 | 2270 |
KLHL22,CSPP1,COPS6,USP11,COPS4,COPS5,UBC |
| 2.764e-02 | -3.59 | SUGP2 (SURP and G-patch domain containing 2) | protein interactions | 10147 | 22 | 7 | 16036 | 2270 |
ATXN1,RNF2,TIMM10,NDUFAF2,BMI1,TMEM126B,SIRT7 |
| 2.764e-02 | -3.59 | PLPPR2 (phospholipid phosphatase related 2) | protein interactions | 64748 | 22 | 7 | 16036 | 2270 |
DNAJC12,NME7,UQCC2,SEC24D,RNF214,WDR73,ANAPC10 |
| 2.764e-02 | -3.59 | KIAA1033 (KIAA1033) | protein interactions | 23325 | 22 | 7 | 16036 | 2270 |
CSNK2A1,WDHD1,RTN4,KIAA0196,ELP2,CCDC53,RPA1 |
| 2.764e-02 | -3.59 | NAA50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit) | protein interactions | 80218 | 22 | 7 | 16036 | 2270 |
FERMT2,JMJD6,TIMM8B,SNU13,FUS,BHLHE40,TARS |
| 2.771e-02 | -3.59 | translation regulator activity | molecular function | GO:0045182 | 34 | 9 | 16491 | 2164 |
IREB2,IGF2BP2,CELF1,IGF2BP1,PABPC1,SAMD4A,ABCF1,PAIP2,IGF2BP3 |
| 2.771e-02 | -3.59 | exoribonuclease activity | molecular function | GO:0004532 | 34 | 9 | 16491 | 2164 |
TOE1,EXOSC2,ERI1,CNOT6,EXOSC4,ERI3,NOCT,PARN,DIS3L2 |
| 2.775e-02 | -3.58 | WHITFIELD_CELL_CYCLE_M_G1 | MSigDB lists | WHITFIELD_CELL_CYCLE_M_G1 | 138 | 26 | 17758 | 2279 |
AOC3,KDM5B,STAG1,FAM189B,AOC2,TLE3,JMJD1C,ELP3,KIAA0586,NFIA,WWC1,PPP2R2A,ZNFX1,AKAP13,DKC1,DSP,ZSCAN5A,SYNCRIP,HIF1A,DNAJB6,PAK1IP1,CTR9,RAN,VCL,TOP1,HMGCR |
| 2.775e-02 | -3.58 | ACTACCT,MIR-196A,MIR-196B | MSigDB lists | ACTACCT,MIR-196A,MIR-196B | 138 | 26 | 17758 | 2279 |
HMGA2,NRAS,LIN28B,TRERF1,BIRC6,SFSWAP,GPCPD1,DDX19A,VSNL1,WDR37,CCDC47,ZNF655,IGF2BP3,RANBP2,LRP1B,GATA6,SMARCC1,RIOK3,SOCS4,LTN1,PPP1R12B,RDX,RBM26,IGF2BP1,USP15,CLK2 |
| 2.777e-02 | -3.58 | RPS6 (ribosomal protein S6) | protein interactions | 6194 | 185 | 36 | 16036 | 2270 |
NIFK,CUL7,OLFM2,FN1,DDX18,PRKCSH,SIRT7,RPS29,PLA2G12A,WDR26,CLINT1,NOP56,RPS16,UPF2,FBL,PABPC1,SERBP1,HNRNPM,PRKACB,TERF2,RPS6KB2,SNU13,ATF4,GNL3,NFIA,EIF2A,IMPDH2,EIF5B,NOP58,TSR1,MYBBP1A,RPL28,COPS5,CUL2,RPS6KB1,NOLC1 |
| 2.783e-02 | -3.58 | craniopharyngeal_duct | COSMIC cancer mutations | craniopharyngeal_duct | 409 | 66 | 17775 | 2278 |
DMXL2,TBKBP1,ABCA3,PCNT,ARID2,RARS2,FANCD2,SMARCA4,RSL1D1,ZNF107,ZNF83,BCOR,PELP1,SKI,RTN1,DHX33,NT5C,CHD2,ETF1,ZNF3,CASP8AP2,CSGALNACT2,FMNL3,ATG9A,ALDH1L2,ARHGEF10,LAMA2,SON,ZNF91,DDX60,UBR4,DHX57,RBBP8,BRCA2,TRRAP,ZNF598,PTPN14,PARD3,DMGDH,BRAF,ITPRIP,RFX1,WDR37,QSER1,USPL1,NISCH,UNC13A,DDX31,ACTR3B,HMGCR,ZNF675,SLC40A1,PRDM16,KDM5A,KCNMA1,OBSCN,RSBN1,PHACTR2,MAP7D1,C8orf33,MBNL2,TBC1D2,ZNF708,DNAH17,ZNF430,ARHGAP12 |
| 2.783e-02 | -3.58 | craniopharyngioma | COSMIC cancer mutations | craniopharyngioma | 409 | 66 | 17775 | 2278 |
DMXL2,TBKBP1,ABCA3,PCNT,ARID2,RARS2,FANCD2,SMARCA4,RSL1D1,ZNF107,ZNF83,BCOR,PELP1,SKI,RTN1,DHX33,NT5C,CHD2,ETF1,ZNF3,CASP8AP2,CSGALNACT2,FMNL3,ATG9A,ALDH1L2,ARHGEF10,LAMA2,SON,ZNF91,DDX60,UBR4,DHX57,RBBP8,BRCA2,TRRAP,ZNF598,PTPN14,PARD3,DMGDH,BRAF,ITPRIP,RFX1,WDR37,QSER1,USPL1,NISCH,UNC13A,DDX31,ACTR3B,HMGCR,ZNF675,SLC40A1,PRDM16,KDM5A,KCNMA1,OBSCN,RSBN1,PHACTR2,MAP7D1,C8orf33,MBNL2,TBC1D2,ZNF708,DNAH17,ZNF430,ARHGAP12 |
| 2.785e-02 | -3.58 | histone H4 acetylation | biological process | GO:0043967 | 51 | 12 | 16441 | 2138 |
KAT8,EP400,TRRAP,BRD4,BRCA2,TRIM16,KANSL1,PER1,TCF3,ELP3,KMT2A,CHD5 |
| 2.787e-02 | -3.58 | nucleotidase activity | molecular function | GO:0008252 | 14 | 5 | 16491 | 2164 |
NT5C,BPNT1,NT5C3A,NT5M,NT5E |
| 2.787e-02 | -3.58 | GTPase activating protein binding | molecular function | GO:0032794 | 14 | 5 | 16491 | 2164 |
FMNL3,MEX3B,FMNL1,PLXNB1,GNAI1 |
| 2.789e-02 | -3.58 | cellular response to glucose starvation | biological process | GO:0042149 | 29 | 8 | 16441 | 2138 |
MYBBP1A,ASNS,ATF4,PMAIP1,UPP1,HSPA5,SLC2A1,PIK3R4 |
| 2.789e-02 | -3.58 | DNA replication initiation | biological process | GO:0006270 | 29 | 8 | 16441 | 2138 |
MCM6,MCM10,POLE2,PRIM2,MCM5,POLA1,ORC5,MCM2 |
| 2.789e-02 | -3.58 | cellular response to monoamine stimulus | biological process | GO:0071868 | 29 | 8 | 16441 | 2138 |
GNG2,ABL1,BDNF,ID1,PDE4B,RYR2,SIRT2,SNCA |
| 2.789e-02 | -3.58 | regulation of extracellular matrix organization | biological process | GO:1903053 | 29 | 8 | 16441 | 2138 |
ABL2,SMAD3,PHLDB2,FSCN1,LEMD3,DDR2,DPP4,TGFB2 |
| 2.790e-02 | -3.58 | KRT76 (keratin 76, type II) | protein interactions | 51350 | 9 | 4 | 16036 | 2270 |
CUL4A,COPS6,COPS5,CUL2 |
| 2.790e-02 | -3.58 | EIF2AK1 (eukaryotic translation initiation factor 2-alpha kinase 1) | protein interactions | 27102 | 9 | 4 | 16036 | 2270 |
EIF2S1,LIG4,CDK6,CDC37 |
| 2.790e-02 | -3.58 | CLIP3 (CAP-GLY domain containing linker protein 3) | protein interactions | 25999 | 9 | 4 | 16036 | 2270 |
RIPK1,CYLD,TNFRSF21,TNFRSF1A |
| 2.790e-02 | -3.58 | FAM117B (family with sequence similarity 117, member B) | protein interactions | 150864 | 9 | 4 | 16036 | 2270 |
FNTB,DYRK1B,BANP,SHMT2 |
| 2.790e-02 | -3.58 | CORO2A (coronin, actin binding protein, 2A) | protein interactions | 7464 | 9 | 4 | 16036 | 2270 |
CORO1A,TBL1X,NCOR1,THAP4 |
| 2.790e-02 | -3.58 | ANXA2P2 (annexin A2 pseudogene 2) | protein interactions | 304 | 9 | 4 | 16036 | 2270 |
FUS,CUL2,RPA1,H2AFX |
| 2.790e-02 | -3.58 | CMBL (carboxymethylenebutenolidase homolog (Pseudomonas)) | protein interactions | 134147 | 9 | 4 | 16036 | 2270 |
ATIC,CUL2,EIF4A2,H2AFX |
| 2.790e-02 | -3.58 | BRWD1 (bromodomain and WD repeat domain containing 1) | protein interactions | 54014 | 9 | 4 | 16036 | 2270 |
SMARCA4,RDX,CUL4A,COPS5 |
| 2.790e-02 | -3.58 | CCDC86 (coiled-coil domain containing 86) | protein interactions | 79080 | 9 | 4 | 16036 | 2270 |
FBL,DLST,SIRT7,NOP56 |
| 2.790e-02 | -3.58 | CDKL1 (cyclin-dependent kinase-like 1 (CDC2-related kinase)) | protein interactions | 8814 | 9 | 4 | 16036 | 2270 |
FKBP5,SUPT5H,TRIP6,CDC37 |
| 2.790e-02 | -3.58 | SNX15 (sorting nexin 15) | protein interactions | 29907 | 9 | 4 | 16036 | 2270 |
RTN4,RABAC1,FN1,KDM1A |
| 2.790e-02 | -3.58 | SNORD3A (small nucleolar RNA, C/D box 3A) | protein interactions | 780851 | 9 | 4 | 16036 | 2270 |
NSD1,FBL,NOP58,NOP56 |
| 2.791e-02 | -3.58 | negative regulation of protein modification process | biological process | GO:0031400 | 584 | 92 | 16441 | 2138 |
SPRED2,ASH1L,UBN1,PAFAH1B1,NF1,BCOR,SIRT2,PRKCA,PIBF1,UBR5,HSPA1A,KDM1A,SKI,SMARCB1,ANAPC1,MPHOSPH10,SOCS1,ZFYVE28,IKBKB,ANAPC11,ANAPC10,SOCS6,MAD1L1,PRMT3,KIRREL2,GMFB,BRCA1,CAV1,SOX4,SNCA,SMAD3,CDC16,PER1,KLF4,DNAJA3,G6PD,SOCS4,ATG7,DUSP19,PKIB,PARD3,NIFK,FOXO1,SUPT6H,UBXN1,SMAD7,PID1,PPP1R1C,AKT1S1,TGFB2,PSMF1,MAD2L2,SFI1,DDIT4,PTPN2,FKBP1A,ABL1,ELL,P3H1,CNST,MYC,FBXO31,ERRFI1,HMGCR,ADARB1,ZNF675,ZFYVE1,KDM5A,TEX14,NXN,PSMA1,MEN1,ISG15,UBE2E1,UBC,HSPA1B,DKK1,TRIB3,KLHL22,GADD45A,PMEPA1,SET,ATM,RBM26,NCOR1,BMP4,NR2F2,IGBP1,SMYD3,PRKAR2A,TESC,ANAPC4 |
| 2.795e-02 | -3.58 | heterochromatin | cellular component | GO:0000792 | 70 | 15 | 17570 | 2233 |
PHC2,RNF40,HMGA2,SIRT6,BAZ2A,ATRX,MBD2,SMARCAD1,RNF2,SIRT2,EME1,TNKS1BP1,CHD5,FOXC1,RING1 |
| 2.795e-02 | -3.58 | UBE2E3 (ubiquitin-conjugating enzyme E2E 3) | protein interactions | 10477 | 91 | 20 | 16036 | 2270 |
CUL4A,NKD2,ATXN1,RANGAP1,RNF43,BRCA1,TRIM37,RING1,UBC,ARIH2,SPOP,RNF111,RNF2,RNF130,TBL1X,CCDC121,CNOT4,MID1,IPO11,RNF114 |
| 2.795e-02 | -3.58 | SAP18 (Sin3A associated protein 18kDa) | protein interactions | 10284 | 91 | 20 | 16036 | 2270 |
SART1,SNU13,TRA2A,TFPI,WDR18,NFIA,PNN,PHGDH,SMARCB1,DDX3X,TADA3,SUFU,POLE2,ADNP,NSF,RNF2,PSAP,NOLC1,BMI1,YARS |
| 2.796e-02 | -3.58 | BENPORATH_ES_CORE_NINE_CORRELATED | MSigDB lists | BENPORATH_ES_CORE_NINE_CORRELATED | 100 | 20 | 17758 | 2279 |
ATF4,WDHD1,SMARCA4,SOX4,SUPT5H,FOXC1,KDM1A,TAF2,TCF7L1,MYBBP1A,GATA6,HIF1A,MYC,TBPL1,RELB,DMRT1,POLR1E,YEATS2,TRIP13,SAP30 |
| 2.796e-02 | -3.58 | chr7q22 | MSigDB lists | chr7q22 | 100 | 20 | 17758 | 2279 |
DNAJC2,CLDN15,TRIP6,CUX1,NAPEPLD,ZNF655,CDHR3,NAMPT,ATXN7L1,DUS4L,GPC2,ZKSCAN1,VGF,ORC5,BUD31,BCAP29,FIS1,COPS6,ZNF3,SRPK2 |
| 2.799e-02 | -3.58 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP | 197 | 35 | 17758 | 2279 |
GGT1,MYCBP2,OSBPL9,SBF2,SCAF8,SKI,VPS18,AMPD3,PRKD3,MLX,ZNF142,MAP3K14,IPO11,CARM1,GTF2H3,IFNGR2,RB1CC1,ZNFX1,OASL,ZNF467,TTC28,PYCR1,UBTF,DYNC1H1,ZFAND3,PDLIM1,DSC2,STX1A,GALNT10,SORCS2,ANKS1A,KDM4C,IPO4,MEF2C,HS2ST1 |
| 2.799e-02 | -3.58 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | 197 | 35 | 17758 | 2279 |
UBN1,SLK,KIAA0232,VPS45,GAS6,PIP4K2A,HDDC2,SREBF2,NUP133,LARP4B,MGLL,SAMD4A,ZNF629,GTF2H3,TUBA1A,SKAP2,ITPA,ATG9A,HSPA5,ATOX1,RNH1,SMARCD3,CA5B,STK10,CHAF1A,RERE,APBB3,HELZ,ACOX1,SPEN,PTPN4,TAF12,IQSEC2,PDCD11,MTMR1 |
| 2.799e-02 | -3.58 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN | 197 | 35 | 17758 | 2279 |
SLC37A3,TCF12,ARHGAP26,DNAJA4,PHGDH,NEDD4,FRRS1,ELL,ANXA7,S100A10,NUP133,FMNL1,MBD2,TOMM34,TRIM14,LYST,DDHD1,AEBP2,CMIP,CRIM1,CDK4,AGPAT4,ELOVL6,RAP1GAP2,PREX1,SCFD2,PLCB1,PLCXD2,MKX,CCDC3,LRRC40,CDK9,BIVM,DUSP19,ANAPC4 |
| 2.807e-02 | -3.57 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | molecular function | GO:0016706 | 45 | 11 | 16491 | 2164 |
P3H1,KDM2A,KDM5B,ALKBH3,KDM5A,ALKBH8,ALKBH1,PLOD1,JMJD6,KDM5C,TMLHE |
| 2.813e-02 | -3.57 | KINASE_ACTIVITY | MSigDB lists | KINASE_ACTIVITY | 367 | 60 | 17758 | 2279 |
XYLB,TNIK,BCKDK,TTN,MINK1,AK2,MVK,MAP3K13,CLK1,TAF1,PDK4,TRIO,DDR2,RIPK1,CSNK2A1,CSNK1A1,RPS6KA5,TGFBR2,MAP2K3,PRKCH,PRKCE,PRKD3,NEK6,PI4KB,PHKA1,GTF2H1,CMPK1,MET,PXK,MAP3K12,FXN,N4BP2,PRPS1,PRKACB,RPS6KB2,SRPK2,CLK2,TNK2,SIK3,CAMKK2,PDK1,CRIM1,COL4A3BP,GALK2,SGK2,PIK3CB,STK10,FGFR1,OXSR1,CDK9,IRAK2,HK2,ATM,NRP1,RPS6KC1,BRSK2,ADK,ZAK,SMG1,STK4 |
| 2.820e-02 | -3.57 | fibrous_tissue_and_uncertain_origin | COSMIC cancer mutations | fibrous_tissue_and_uncertain_origin | 285 | 48 | 17775 | 2278 |
CARS,BRAF,FN1,NF1,CSPP1,MLH1,SAFB2,IGSF1,PDE3A,SMARCB1,ABL1,SRSF2,SOCS1,ATIC,PPFIBP1,JAZF1,DTNBP1,TIMELESS,CHD2,CD44,FBL,MET,NRIP1,KIAA1549,SF3A1,NRAS,MYO10,SETD2,JMJD1C,TPM4,KIAA0586,MEN1,SLC26A11,FGFR1,DHX57,SEC31A,EPRS,CAMK2D,RANBP2,ASCC3,BAZ2B,TRRAP,SUFU,FAT1,HIPK2,ATM,FUS,CPT1C |
| 2.821e-02 | -3.57 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 119 | 23 | 17758 | 2279 |
ACSL5,HMGA2,UPP1,TCEB3,PREX1,MARCKSL1,PHACTR2,SATB2,COTL1,ODC1,LYRM2,PHLDA2,CHN1,JAG1,NEK6,SLC7A11,CELF1,GMDS,NR2F2,CD44,BMI1,TSPAN5,PTPRK |
| 2.834e-02 | -3.56 | Eukaryotic Transcription Initiation | WikiPathways | WP405 | 41 | 10 | 4455 | 564 |
POLR3D,GTF2H3,POLR1A,POLR3E,GTF2H1,TAF12,POLR1B,POLR3B,POLR1E,POLR2A |
| 2.845e-02 | -3.56 | superpathway of pyrimidine ribonucleotides de novo biosynthesis | BIOCYC pathways | HUMAN_PWY0-162 | 13 | 5 | 907 | 131 |
CAD,UMPS,NME1-NME2,CMPK1,NME7 |
| 2.845e-02 | -3.56 | superpathway of purine nucleotides de novo biosynthesis I | BIOCYC pathways | META_PWY-841 | 13 | 5 | 907 | 131 |
GART,NME1-NME2,IMPDH2,PPAT,ATIC |
| 2.845e-02 | -3.56 | GSE16755_CTRL_VS_IFNA_TREATED_MAC_UP | MSigDB lists | GSE16755_CTRL_VS_IFNA_TREATED_MAC_UP | 184 | 33 | 17758 | 2279 |
TCF12,ESCO1,EIF3C,ID2,TMEM177,BCOR,XPO7,FAM13A,TGFBR2,UBR5,GIT2,SFR1,ABL1,DUS4L,ARHGAP18,TRMT12,ZNF518B,MIOS,RNMT,STAMBP,ATP6V0A1,TMEM175,PHF6,HELZ,TP53BP1,SNAP23,WDR73,ARHGAP12,BMI1,PDSS2,XPO6,ZNF589,MEF2C |
| 2.845e-02 | -3.56 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | 184 | 33 | 17758 | 2279 |
KLHL24,RELL2,ZNF76,PHF3,CLK1,SMAD7,ZFP36L1,CCNL2,SEC16A,FAM8A1,MGA,SFI1,LPIN1,PRKCE,SRSF2,DHX33,SLC38A2,HARS2,CPNE7,CNOT4,SNX29,MARCH9,FBXW4,KDM5B,CRIM1,EIF4A2,CAMSAP2,PDE2A,PEAK1,BTBD11,ATXN7,HNRNPH3,IFT140 |
| 2.845e-02 | -3.56 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 184 | 33 | 17758 | 2279 |
HLTF,MAD2L2,SLC25A20,SUV39H2,FGGY,ATIC,STC2,HIRIP3,RDX,B3GNTL1,ALDH18A1,PNPLA3,GMDS,VCL,TRIP13,IPO11,CARM1,RABEPK,GINS3,ZNF821,RAB7A,POLA1,EYA3,PCMT1,PEAK1,TMEM187,RDH11,DDAH2,PAM,ATG7,FNTB,TXN2,ZNF589 |
| 2.847e-02 | -3.56 | sequence-specific double-stranded DNA binding | molecular function | GO:1990837 | 670 | 105 | 16491 | 2164 |
TCF12,ZNF516,SMARCA4,PBX1,HLTF,FOSL2,SMARCB1,CHD7,RRN3,NRF1,SREBF2,ZFHX3,IKZF5,DHX33,RELB,ZNF148,CHD2,ZNF85,ZNF460,ETV1,KMT2A,DDN,AEBP2,ATF4,ZNF195,PPARG,ZNF680,BAZ2A,NR6A1,ZNF480,NFIA,RFX2,CUX1,POU2F1,MEF2D,SOX4,ZSCAN2,MCM2,GZF1,BATF3,SMAD3,UBTF,SKIL,MSX2,SMARCC1,GATA6,SIX5,CC2D1B,PER1,KLF4,E2F4,ARNTL,CEBPZ,RUNX1,DLX2,ZC3H8,ZBTB11,MEF2C,HMGA2,MCM10,EGR1,RFX1,PAX2,TCF3,DPF2,CENPB,NFX1,HES6,BARX2,ZNF691,MLX,ZNF586,ZNF561,SUV39H2,MCM5,MBD2,MYC,YBX3,PRMT5,NRIP1,DMRT1,MYB,TOP1,ZNF675,GATAD2B,MSX1,RREB1,PAXBP1,PSPC1,ARID5B,PRDM1,ONECUT2,FOXC1,TCF7L2,ZNF708,NSD1,ARID3B,ORC5,TBX3,MSH3,PURB,ZNF430,RBPJ,SMYD3,DDIT3 |
| 2.853e-02 | -3.56 | Ibandronate Action Pathway | SMPDB pathways | SMP00079 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Mevalonic aciduria | SMPDB pathways | SMP00510 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Wolman disease | SMPDB pathways | SMP00511 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Hypercholesterolemia | SMPDB pathways | SMP00209 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Steroid Biosynthesis | SMPDB pathways | SMP00023 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Smith-Lemli-Opitz Syndrome (SLOS) | SMPDB pathways | SMP00389 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Pamidronate Action Pathway | SMPDB pathways | SMP00117 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Atorvastatin Action Pathway | SMPDB pathways | SMP00131 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | CHILD Syndrome | SMPDB pathways | SMP00387 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Zoledronate Action Pathway | SMPDB pathways | SMP00107 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Cholesteryl ester storage disease | SMPDB pathways | SMP00508 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Lysosomal Acid Lipase Deficiency (Wolman Disease) | SMPDB pathways | SMP00319 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Lovastatin Action Pathway | SMPDB pathways | SMP00099 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Risedronate Action Pathway | SMPDB pathways | SMP00112 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Simvastatin Action Pathway | SMPDB pathways | SMP00082 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Fluvastatin Action Pathway | SMPDB pathways | SMP00119 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Rosuvastatin Action Pathway | SMPDB pathways | SMP00092 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Desmosterolosis | SMPDB pathways | SMP00386 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Pravastatin Action Pathway | SMPDB pathways | SMP00089 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Alendronate Action Pathway | SMPDB pathways | SMP00095 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Chondrodysplasia Punctata II- X Linked Dominant (CDPX2) | SMPDB pathways | SMP00388 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Cerivastatin Action Pathway | SMPDB pathways | SMP00111 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.853e-02 | -3.56 | Hyper-IgD syndrome | SMPDB pathways | SMP00509 | 21 | 7 | 978 | 148 |
SQLE,LSS,IDI1,MVK,FDPS,HMGCR,FDFT1 |
| 2.858e-02 | -3.56 | ZRSR2 (zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2) | protein interactions | 8233 | 42 | 11 | 16036 | 2270 |
SART1,SRSF2,SDCBP2,SF3A3,JMJD6,PDCD7,C8orf33,GPATCH11,CLK2,SRPK2,SF3A1 |
| 2.858e-02 | -3.56 | SEC23B (Sec23 homolog B, COPII coat complex component) | protein interactions | 10483 | 42 | 11 | 16036 | 2270 |
SEC24A,SEC31A,PXN,FN1,SEC24D,SEC24C,SIRT7,HOXA3,SUMO3,CSNK1A1,SRPK2 |
| 2.858e-02 | -3.56 | CASP6 (caspase 6) | protein interactions | 839 | 42 | 11 | 16036 | 2270 |
BIRC6,CHD3,PRKAB2,EIF2S1,VIM,COPS6,DSP,MAPT,NEDD4,CASP10,TOP1 |
| 2.858e-02 | -3.56 | CLIC1 (chloride intracellular channel 1) | protein interactions | 1192 | 42 | 11 | 16036 | 2270 |
MTHFD2,CUL7,FN1,HSD17B10,FRA10AC1,PSMA1,ATP6V0A1,RDX,HIBCH,CPT1A,ISG15 |
| 2.858e-02 | -3.56 | FUBP3 (far upstream element (FUSE) binding protein 3) | protein interactions | 8939 | 42 | 11 | 16036 | 2270 |
CUL7,SMARCC1,FN1,COPS5,SMARCAD1,SIRT7,ATXN1,RNF2,ISG15,RAB10,RPA1 |
| 2.858e-02 | -3.56 | AGO1 (argonaute RISC catalytic component 1) | protein interactions | 26523 | 42 | 11 | 16036 | 2270 |
KHDRBS1,COPS5,AGO2,FKBP5,MEX3B,BMI1,PABPC1,AGO3,POLR2A,UBC,TNRC6A |
| 2.858e-02 | -3.56 | SS18 (synovial sarcoma translocation, chromosome 18) | protein interactions | 6760 | 42 | 11 | 16036 | 2270 |
DPF3,SMARCC1,ARID2,DPF2,SMARCD3,SMARCA4,ARID1A,BRD9,ARID1B,MLLT10,SMARCB1 |
| 2.867e-02 | -3.55 | ATATGCA,MIR-448 | MSigDB lists | ATATGCA,MIR-448 | 204 | 36 | 17758 | 2279 |
PHF3,DNM3,ARID2,CLK1,PRKAB2,NHS,DLGAP4,MED13L,NAV1,SLC7A11,SYN2,MYH3,NBEA,NRIP1,ETV1,SERBP1,LYST,GPM6A,GPHN,WDFY3,ANK2,RAB7A,AGAP1,MBNL2,GNAI1,DAGLA,RANBP2,KPNA3,TBX3,ARNTL,DPP4,RBM26,VASH2,DCAF5,MEF2C,STK4 |
| 2.871e-02 | -3.55 | CYTOCHROME_B5_2 | prosite domains | PS50255 | 10 | 4 | 11866 | 1504 |
FADS1,HERC2,CYB5B,CYB5D1 |
| 2.873e-02 | -3.55 | embryonic epithelial tube formation | biological process | GO:0001838 | 124 | 24 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,LUZP1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SOX4,TCTN1,SKI,HIF1A,BMP4,APAF1,PRKACB,STK4,HS2ST1,MTHFD1 |
| 2.873e-02 | -3.55 | V$BACH1_01 | MSigDB lists | V$BACH1_01 | 251 | 43 | 17758 | 2279 |
RELL2,SSH2,SEC24D,TNXB,RTN4,GIGYF2,PHLDA2,ZNF827,ELL,ECM1,SRSF2,NEK6,S100A10,ADCK4,SRPK2,MYB,FAM184A,PPP1R9B,NRAS,LAMC1,RB1CC1,EIF3J,RAP1GAP2,DLG4,C11orf49,NCDN,GNAI1,YIF1A,DYNC1H1,TSR1,DSC2,ZNF436,CSRNP1,HSPB8,MPV17,CSMD3,DIRAS1,TRAF3,ITGB4,RAB30,DDIT3,TNRC6A,LPP |
| 2.873e-02 | -3.55 | V$AP1_01 | MSigDB lists | V$AP1_01 | 251 | 43 | 17758 | 2279 |
RELL2,SSH2,PRPF38B,DPH1,MMRN2,FAM46B,TNXB,SPATS2,TGFBR2,FAM49A,PHLDA2,MMP7,CCDC50,ANXA7,NEK6,SLC38A2,ADCK4,ITGAX,VCL,FAM184A,MYB,PEA15,PPP1R9B,FGF9,LAMC1,TEX19,RB1CC1,BAZ2A,EIF3J,RAP1GAP2,TBXAS1,HSD3B7,NCDN,VDR,DYNC1H1,LRP1B,GADD45A,HSPB8,CSMD3,TRAF3,DIRAS1,TNRC6A,ATXN7L2 |
| 2.873e-02 | -3.55 | V$GFI1_01 | MSigDB lists | V$GFI1_01 | 251 | 43 | 17758 | 2279 |
TCF12,CGN,MAP2K5,LUZP1,PPARGC1B,DDR2,C1QTNF7,PPP2R2A,ID2,PBX1,FAM122B,MBNL1,SRSF2,SREBF2,ATP5G2,LRP2BP,CACNB2,JAZF1,CALN1,C15orf41,TOP1,PEA15,DPF3,BDNF,AGPAT4,JMJD1C,ABCF2,XPO5,NFIA,MEX3B,SGK2,SOX4,CAMK2D,GADD45A,PDLIM1,HOXA3,INTS9,SLC4A7,RPS6KB1,RBM26,BMP4,NR2F2,MEF2C |
| 2.874e-02 | -3.55 | TPR_1 | interpro domains | IPR001440 | 52 | 12 | 18293 | 2341 |
TTC1,TTC27,PPID,IFIT5,CTR9,TTC3,FKBP5,GTF3C3,TTC17,TTC28,TOMM34,TRAPPC12 |
| 2.880e-02 | -3.55 | nitrogen compound transport | biological process | GO:0071705 | 487 | 78 | 16441 | 2138 |
THOC5,SLC48A1,NF1,SLC52A3,PRKAB2,DDX19A,NTSR1,SLC29A1,NUP43,SLC6A8,NUP160,HNRNPA3,MMP7,SRSF2,ABCA12,NUP133,VGF,SLC38A2,RAN,HRG,SLC35C2,CPSF3,SLC25A23,ZC3H3,SEH1L,SLC38A6,SLC3A2,SLC38A1,NOL6,COL4A3BP,ABCC2,SLC35D1,NUP214,FLVCR1,SNCA,SLC7A1,GLS,RANBP2,ARL6IP5,DISP1,SLC25A26,SMG1,SERINC5,SUPT6H,PRAF2,SLC25A12,SMG7,KIF5C,IGF2BP2,XPO7,SLC1A1,POM121,SLC25A20,IGF2BP3,SLC7A11,SLC38A5,ATXN2,NISCH,UPF2,IGF2BP1,SLC6A16,BDNF,XPO5,RAPGEF4,SNAP25,TMEM241,CPT1A,SYT1,ANXA1,SLC23A2,SERINC1,STX1A,SNAP23,SLC25A19,NCBP2,SLC52A2,SLC16A10,SLC43A1 |
| 2.882e-02 | -3.55 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological process | GO:0000288 | 57 | 13 | 16441 | 2138 |
EXOSC2,DCP1B,EIF4A2,ZFP36L1,CNOT6,MLH1,EXOSC4,CNOT4,NOCT,PARN,TNKS1BP1,PABPC1,EDC3 |
| 2.882e-02 | -3.55 | cellular response to drug | biological process | GO:0035690 | 57 | 13 | 16441 | 2138 |
CAD,BRAF,EGR1,PDE4A,PPAT,MYC,PDE4B,DPEP1,UMPS,GAS6,PDE2A,KCNH2,MEF2C |
| 2.884e-02 | -3.55 | LRPPRC (leucine-rich pentatricopeptide repeat containing) | protein interactions | 10128 | 80 | 18 | 16036 | 2270 |
ADARB1,NAA38,CUL7,FN1,FOXO1,USP49,SIRT7,MAP1S,METTL22,BRE,NEK6,MYC,SHMT2,RNF2,NFKBIB,TNFRSF10D,BMI1,RPS6KB2 |
| 2.884e-02 | -3.55 | ITSN2 (intersectin 2) | protein interactions | 50618 | 80 | 18 | 16036 | 2270 |
BCCIP,ANKRD17,KHDRBS1,EPS15L1,TRIO,GPNMB,MBNL1,ERC1,SEMA6A,KDM1A,SH3GL1,DST,YLPM1,LUC7L3,SYNJ2,CCDC88C,RABEP1,KIAA1549 |
| 2.884e-02 | -3.55 | LMNB1 (lamin B1) | protein interactions | 4001 | 80 | 18 | 16036 | 2270 |
DCTN3,CUL7,MCM10,ATF4,FN1,URB2,SMARCAD1,POU2F1,SMARCA4,VIM,PRKCA,GIT2,UBC,RPA1,ZZEF1,HNRNPM,SPTAN1,TMPO |
| 2.884e-02 | -3.55 | COPS3 (COP9 signalosome subunit 3) | protein interactions | 8533 | 80 | 18 | 16036 | 2270 |
FBXO17,FBXW4,CUL4A,BTBD2,KLHL18,SF3A3,CSNK2A1,TOR1AIP2,COPS4,COPS3,COPS5,LRP2BP,IKBKB,CUL2,COPS7B,COPS6,SRP14,DDIT3 |
| 2.888e-02 | -3.54 | RBM14 (RNA binding motif protein 14) | protein interactions | 10432 | 97 | 21 | 16036 | 2270 |
CUL7,FN1,DROSHA,PLRG1,ZC3H18,RSL1D1,SYT1,RPA1,HNRNPR,COPS5,CUL2,TRAF3,RNF2,RUNX1,COPS6,BMI1,FTSJ3,HNRNPM,TOP1,SF3A1,PRPF19 |
| 2.888e-02 | -3.54 | Downregulation of SMAD2/3:SMAD4 transcriptional activity | REACTOME pathways | R-HSA-2173795 | 23 | 7 | 8202 | 1117 |
SMAD3,SKIL,RNF111,NCOR2,NCOR1,UBC,SKI |
| 2.888e-02 | -3.54 | APC-Cdc20 mediated degradation of Nek2A | REACTOME pathways | R-HSA-179409 | 23 | 7 | 8202 | 1117 |
ANAPC1,CDC16,ANAPC4,UBC,UBE2E1,ANAPC11,ANAPC10 |
| 2.888e-02 | -3.54 | Telomere C-strand (Lagging Strand) Synthesis | REACTOME pathways | R-HSA-174417 | 23 | 7 | 8202 | 1117 |
RFC4,RFC3,APEX1,POLE2,PRIM2,POLA1,RPA1 |
| 2.888e-02 | -3.54 | Amino acid synthesis and interconversion (transamination) | REACTOME pathways | R-HSA-70614 | 23 | 7 | 8202 | 1117 |
GLS,ASNS,ALDH18A1,PSAT1,PHGDH,PYCRL,PYCR1 |
| 2.891e-02 | -3.54 | genital_tract-extragonadal-germ_cell_tumour-teratoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-teratoma | 35 | 9 | 17775 | 2278 |
BAZ2B,BRAF,NRAS,ADAMTSL3,INTS7,NF1,JMJD1C,RPS6KB2,SMARCB1 |
| 2.892e-02 | -3.54 | reciprocal meiotic recombination | biological process | GO:0007131 | 40 | 10 | 16441 | 2138 |
HFM1,XRCC2,MSH3,RAD51B,ATM,MLH1,MSH4,CCNB1IP1,TRIP13,RAD54B |
| 2.892e-02 | -3.54 | reciprocal DNA recombination | biological process | GO:0035825 | 40 | 10 | 16441 | 2138 |
HFM1,XRCC2,MSH3,RAD51B,ATM,MLH1,MSH4,CCNB1IP1,TRIP13,RAD54B |
| 2.892e-02 | -3.54 | ventricular cardiac muscle tissue morphogenesis | biological process | GO:0055010 | 40 | 10 | 16441 | 2138 |
FKBP1A,TNNC1,PTCD2,DLL4,SMAD7,RYR2,RBPJ,TPM1,DSP,FOXC1 |
| 2.892e-02 | -3.54 | negative regulation of fat cell differentiation | biological process | GO:0045599 | 40 | 10 | 16441 | 2138 |
TRIB3,MSX2,JAG1,FOXO1,INSIG1,ARNTL,CCDC85B,SIRT2,TCF7L2,DDIT3 |
| 2.892e-02 | -3.54 | posttranscriptional gene silencing | biological process | GO:0016441 | 40 | 10 | 16441 | 2138 |
SMAD3,LIN28B,DROSHA,XPO5,AGO2,CNOT6,RAN,CELF1,AGO3,TNRC6A |
| 2.894e-02 | -3.54 | GDHRDH | prints domains | PR00081 | 53 | 10 | 4759 | 462 |
DECR1,HSDL2,DCXR,CBR4,RDH10,HSD17B10,BDH2,HSD17B12,RDH11,HSD17B14 |
| 2.895e-02 | -3.54 | cell surface receptor signaling pathway involved in heart development | biological process | GO:0061311 | 19 | 6 | 16441 | 2138 |
MSX2,MSX1,DLL4,RBPJ,JAG1,BMP4 |
| 2.895e-02 | -3.54 | striated muscle hypertrophy | biological process | GO:0014897 | 24 | 7 | 16441 | 2138 |
RYR2,CAMK2D,TTN,CAMTA2,GATA6,PDLIM5,MEF2C |
| 2.895e-02 | -3.54 | nucleotide-excision repair, DNA gap filling | biological process | GO:0006297 | 24 | 7 | 16441 | 2138 |
LIG4,RFC4,POLB,RFC3,POLK,UBC,RPA1 |
| 2.896e-02 | -3.54 | regulation of cellular catabolic process | biological process | GO:0031329 | 599 | 94 | 16441 | 2138 |
USP7,FEZ2,RCHY1,CSNK2A1,SIRT2,AMBRA1,ABL2,TMEM150C,ANAPC1,NEK6,SREBF2,UCHL5,WAC,ANAPC11,ANAPC10,MAD1L1,FHIT,MET,HTRA2,KAT8,ZBTB17,TRIM13,SIRT6,RAB7A,SUMO3,CAV1,USP36,SNCA,FBXL5,ZC3H12A,CDC16,SMARCC1,NSMCE2,SOCS4,ATG7,ADAM9,SCARB1,CLU,ANXA2,USP11,UQCC2,MAPT,USP15,WDR75,FOXO1,TAF1,AGO2,UBXN1,NKD2,OPHN1,SMAD7,TRIM22,SOGA1,PIP4K2A,PSMF1,MAD2L2,DDIT4,ABL1,RNF40,UBE3A,ENTPD5,RDX,LRSAM1,PABPC1,WDFY3,USP49,RB1CC1,USP42,DHX34,TEX14,PSMA1,USP10,PTK2,SUPT5H,UBE2K,CPT1A,PIK3CB,HERPUD1,POLR3A,ARIH2,UBE2E1,UBC,IRS1,TRIB3,KLHL22,RPL28,HIF1A,HERC1,RRAGA,ATM,USP20,APAF1,NCOR1,ANAPC4 |
| 2.899e-02 | -3.54 | nuclear pore outer ring | cellular component | GO:0031080 | 10 | 4 | 17570 | 2233 |
NUP43,NUP160,NUP133,SEH1L |
| 2.899e-02 | -3.54 | GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_UP | MSigDB lists | GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_UP | 158 | 29 | 17758 | 2279 |
CHD9,BDNF,EPM2AIP1,ADAMTSL3,FAM111B,DDX18,EYA3,AP4B1,BCS1L,GTF2IRD1,CAMSAP2,ARSJ,CSTA,GUF1,CHAF1A,CEP164,HELZ,GPC2,DUS4L,GATC,CC2D1B,ARL4A,DNAH17,ABCC3,HEATR1,GEMIN4,CLU,C6orf223,DOCK6 |
| 2.900e-02 | -3.54 | PELP1 (proline, glutamate and leucine rich protein 1) | protein interactions | 27043 | 58 | 14 | 16036 | 2270 |
CUL7,FN1,SMARCAD1,SIRT7,WDR18,BCAS3,SENP3,RNF2,MDN1,NOLC1,KDM1A,RPA1,SNCA,TOM1L1 |
| 2.900e-02 | -3.54 | DYRK1B (dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B) | protein interactions | 9149 | 58 | 14 | 16036 | 2270 |
KAT8,DYRK1B,EP400,SIPA1L3,ZNF516,HIPK2,ARNTL,KIAA0232,ENAH,ICE2,USP11,AKAP11,MAP2K3,SKI |
| 2.900e-02 | -3.54 | MAP4 (microtubule associated protein 4) | protein interactions | 4134 | 58 | 14 | 16036 | 2270 |
CUL4A,FN1,HNRNPR,SLK,SIRT7,HSPA5,EIF2S1,WDHD1,FLNB,SERBP1,POLR2A,ISG15,UBC,RPA1 |
| 2.900e-02 | -3.54 | KBTBD7 (kelch repeat and BTB (POZ) domain containing 7) | protein interactions | 84078 | 58 | 14 | 16036 | 2270 |
PHC2,AEBP2,SURF2,PI4KB,UBXN1,PCMT1,RBM26,FOSL2,C8orf33,BLMH,CPT1A,BRSK2,ERC1,GBF1 |
| 2.909e-02 | -3.54 | IKEDA_MIR30_TARGETS_UP | MSigDB lists | IKEDA_MIR30_TARGETS_UP | 113 | 22 | 17758 | 2279 |
BDNF,CHD9,B4GALT5,SSBP2,SON,PIP4K2A,NEDD4,PTPN2,IRS1,ELL,ASAP1,WDR7,HIC2,SOCS6,LARGE,GTF2H1,SLC4A7,CNOT6,NRIP1,CDK6,TNRC6A,USP15 |
| 2.912e-02 | -3.54 | V$GATA1_01 | MSigDB lists | V$GATA1_01 | 231 | 40 | 17758 | 2279 |
FEZ2,TRERF1,ANKRD17,C16orf52,TNXB,PPP2R2A,RCAN1,RSF1,IL17RE,ZNF827,HR,SREBF2,WAC,TNPO3,ZMYM2,YARS,MAML3,SOBP,AEBP2,TLE3,PPP1R21,NFIA,R3HDM1,POU2F1,ARL5B,MAK16,RAB10,NCDN,RERE,SPOP,SNCA,TCF7L1,SUFU,GADD45A,SYNCRIP,RPS6KB1,CLU,TSPAN5,KIF1B,ATXN7L2 |
| 2.913e-02 | -3.54 | NAP1L5 (nucleosome assembly protein 1-like 5) | protein interactions | 266812 | 27 | 8 | 16036 | 2270 |
ZBTB21,EVL,TSPYL4,FAM207A,RNF138,NOL6,COL4A3BP,CEP126 |
| 2.913e-02 | -3.54 | AP3S1 (adaptor-related protein complex 3, sigma 1 subunit) | protein interactions | 1176 | 27 | 8 | 16036 | 2270 |
IRS1,SRPRB,FLNC,SLC30A3,KRT7,DTNBP1,CDC73,AGO3 |
| 2.913e-02 | -3.54 | SYNE1 (spectrin repeat containing, nuclear envelope 1) | protein interactions | 23345 | 27 | 8 | 16036 | 2270 |
TNIK,IFT57,DTNBP1,NLN,RNF2,CEP63,BMI1,TERF2 |
| 2.913e-02 | -3.54 | CLUH (clustered mitochondria (cluA/CLU1) homolog) | protein interactions | 23277 | 27 | 8 | 16036 | 2270 |
TRIM16,CELSR3,SIRT7,ABCF2,WDR37,FAHD1,YARS,ARPC3 |
| 2.913e-02 | -3.54 | FBXO5 (F-box protein 5) | protein interactions | 26271 | 27 | 8 | 16036 | 2270 |
ANAPC1,CDC16,MYC,ANAPC11,SHMT2,BRCA1,EVI5,ANAPC4 |
| 2.913e-02 | -3.54 | LMNB2 (lamin B2) | protein interactions | 84823 | 27 | 8 | 16036 | 2270 |
CUL7,BANF1,SIRT7,FNTB,SVIL,RNF2,SOX4,TMPO |
| 2.913e-02 | -3.54 | MIER2 (mesoderm induction early response 1, family member 2) | protein interactions | 54531 | 27 | 8 | 16036 | 2270 |
BRCA2,EHMT2,EHMT1,WIZ,RNF2,USP11,AGAP1,MGA |
| 2.913e-02 | -3.54 | DPP9 (dipeptidyl-peptidase 9) | protein interactions | 91039 | 27 | 8 | 16036 | 2270 |
SURF2,DUS3L,PLPPR2,MTR,AARS,TMCO6,TOM1L1,LPP |
| 2.914e-02 | -3.54 | cilium assembly | biological process | GO:0042384 | 169 | 31 | 16441 | 2138 |
CEP83,TTLL5,IFT57,PCNT,CELSR3,WDPCP,KIAA0586,TMEM216,MKS1,CCDC113,CEP126,PIBF1,ONECUT2,DNAH1,RPGRIP1L,CCDC28B,ARMC4,CEP164,IFT81,TMEM237,WDR35,CEP290,E2F4,ARL13B,IFT140,CCDC40,BBIP1,DYNC2H1,FNBP1L,LAMA5,ATP6V0D1 |
| 2.914e-02 | -3.54 | HALLMARK_HEDGEHOG_SIGNALING | MSigDB lists | HALLMARK_HEDGEHOG_SIGNALING | 35 | 9 | 17758 | 2279 |
RTN1,CELSR1,NF1,TLE3,OPHN1,MYH9,NRP1,AMOT,CDK6 |
| 2.916e-02 | -3.53 | MORF_CCNI | MSigDB lists | MORF_CCNI | 88 | 18 | 17758 | 2279 |
ATF4,BAZ2A,KHDRBS1,DPF2,EIF4A2,RSL1D1,TMEM123,DDX49,EIF3H,ARPC3,SRSF2,LSM14A,ACP1,ANP32B,PTP4A2,TROVE2,SRP14,SF3A1 |
| 2.916e-02 | -3.53 | CCAGGGG,MIR-331 | MSigDB lists | CCAGGGG,MIR-331 | 88 | 18 | 17758 | 2279 |
RELL2,MINK1,CRIM1,B4GALT5,DLGAP4,VTI1A,PCNXL2,XPO7,SEMA6A,PHC2,CACNB1,SOCS1,HOXA3,NBEA,IGF2BP1,MBD6,GGT7,SLC25A1 |
| 2.916e-02 | -3.53 | ELVIDGE_HIF1A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_TARGETS_DN | 88 | 18 | 17758 | 2279 |
ZNF292,INSIG2,PDK1,SLC2A1,ATXN1,CAV1,NOL3,FAM13A,ANGPTL4,PLIN2,KDM4B,DSC2,PTRF,HK2,AHNAK2,PAM,RBPJ,YEATS2 |
| 2.918e-02 | -3.53 | dolichyl-diphosphooligosaccharide biosynthesis | BIOCYC pathways | HUMAN_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS | 9 | 4 | 907 | 131 |
DPM3,ALG5,ALG6,ALG8 |
| 2.922e-02 | -3.53 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | 191 | 34 | 17758 | 2279 |
SLC12A7,SRM,SPRED2,PRDX6,TTC27,CCDC53,ST6GAL1,NDUFB5,HSD17B10,SMAD7,TUBB6,SSBP2,BZW2,BIRC2,MFHAS1,PIP4K2A,AMPD3,IKBKB,TIMELESS,TTC3,PRMT3,EVL,PDK1,APEX1,WLS,IL6R,POLR3A,PWP1,SRCAP,DDX50,MBTD1,VPS37B,FNTB,IPO4 |
| 2.922e-02 | -3.53 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP | 191 | 34 | 17758 | 2279 |
SART1,STX8,TRIM16,ACTG1,FAM13A,SAFB2,PABPC4,DDIT4,FARSA,NDUFV1,MBD2,SLC39A7,ANXA5,COPS7B,HNRNPM,MTHFD1,NRAS,PRIM2,LSM12,HSPA5,WDR18,SUMO3,MRPS10,MAPK1IP1L,SOX4,C8orf33,DDX49,SEC31A,DDX3X,LSM14A,HIF1A,HNRNPR,PTP4A2,BAG1 |
| 2.922e-02 | -3.53 | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDM_UP | 191 | 34 | 17758 | 2279 |
MCM10,CUL7,CCDC58,GPBP1L1,GYG1,PITPNM1,DCTPP1,PTPN2,BCAS2,ATG3,VPS72,NCKIPSD,SSBP1,MGLL,MPST,SRPK2,KDM3B,SKIV2L,RBCK1,SSFA2,IL6R,KLF6,WARS,TPK1,SPOP,RHOU,MSRA,EIF4ENIF1,BAZ2B,VPS37B,CTAGE5,BAG1,PKIB,USP15 |
| 2.922e-02 | -3.53 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | 191 | 34 | 17758 | 2279 |
SLC12A7,PPDPF,SSH2,RBM33,SESTD1,MFGE8,KLC4,ADAMTS6,PRKCA,ARID1B,MFHAS1,MTUS1,RABGAP1L,RASSF3,IKBKB,CCDC88C,CHD9,AKAP8L,GPHN,CRADD,RAP1GAP2,ZMYM5,ARHGEF10,MCL1,TBC1D16,SLC50A1,ARMC3,RERE,SMAD3,SYCP2L,TASP1,TMEM219,NRP1,SH3PXD2A |
| 2.928e-02 | -3.53 | DARS (aspartyl-tRNA synthetase) | protein interactions | 1615 | 69 | 16 | 16036 | 2270 |
USP7,GARS,CUL7,FN1,ATP6V1A,VTA1,MARS,AARS,CIAPIN1,UBC,CAD,EPRS,RARS,XPNPEP1,EIF2S1,ZNF598 |
| 2.928e-02 | -3.53 | NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)) | protein interactions | 4722 | 69 | 16 | 16036 | 2270 |
NDUFA5,SLC3A2,CUL7,FN1,TMEM126B,NDUFB5,NDUFS7,UBC,NDUFB3,NDUFV1,MYC,SURF1,NDUFAF5,SHMT2,SSBP1,TMEM14C |
| 2.929e-02 | -3.53 | GNB5 (guanine nucleotide binding protein (G protein), beta 5) | protein interactions | 10681 | 37 | 10 | 16036 | 2270 |
GNG2,OLFM2,ANXA7,NR6A1,EIF3J,COPS5,GNG7,MCM2,GNG5,RPA1 |
| 2.929e-02 | -3.53 | HMGB2 (high mobility group box 2) | protein interactions | 3148 | 37 | 10 | 16036 | 2270 |
APEX1,FN1,SET,POU2F1,SHMT2,CSNK1A1,SCAF8,PKNOX1,CHAF1A,PGD |
| 2.929e-02 | -3.53 | PPL (periplakin) | protein interactions | 5493 | 37 | 10 | 16036 | 2270 |
SKIL,USP7,COL17A1,DROSHA,PPHLN1,PSMA1,VIM,EVPL,AHCYL1,UBC |
| 2.929e-02 | -3.53 | TGFB1I1 (transforming growth factor beta 1 induced transcript 1) | protein interactions | 7041 | 37 | 10 | 16036 | 2270 |
SMAD3,FKBP1A,PXN,SMAD7,PTPN12,SVIL,PTK2,TGFBR2,VCL,GIT2 |
| 2.929e-02 | -3.53 | PKP2 (plakophilin 2) | protein interactions | 5318 | 37 | 10 | 16036 | 2270 |
EFNB2,JUP,DSC2,DROSHA,DSG2,RNF2,BMI1,DSP,POLR3A,CLK2 |
| 2.929e-02 | -3.53 | BAG4 (BCL2-associated athanogene 4) | protein interactions | 9530 | 37 | 10 | 16036 | 2270 |
CUL4A,DNAJB6,COPS5,DCP1B,CUL2,TNFRSF1A,MCL1,HSPA1A,HSPA1B,EDC3 |
| 2.929e-02 | -3.53 | GSTP1 (glutathione S-transferase pi 1) | protein interactions | 2950 | 37 | 10 | 16036 | 2270 |
CUL7,FN1,SCAF1,COPS5,SIRT7,CUL2,LIG4,FUS,MLH1,ISG15 |
| 2.930e-02 | -3.53 | HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR | MSigDB lists | HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR | 52 | 12 | 17758 | 2279 |
MGAT2,PTP4A1,MIF4GD,SYNCRIP,APEX1,DNAJB6,IPP,PAG1,SLC50A1,TOMM34,UBE2E1,LYPLA2 |
| 2.938e-02 | -3.53 | organic cyclic compound catabolic process | biological process | GO:1901361 | 432 | 70 | 16441 | 2138 |
CYP24A1,TRERF1,LIN28B,PAPD4,DCP1B,RPS29,PPP2R2A,NT5C3A,HMOX2,TNKS1BP1,PDE3A,PABPC4,EDC3,AMPD3,RPS16,ERI1,NT5C,ETF1,OGG1,SKIV2L,SKIV2L2,ITPA,UPP1,ALDH1L2,NUDT15,PDE8B,HPRT1,NOCT,MUTYH,SMG1,DROSHA,TATDN3,PDE4B,SMG7,ZFP36L1,MLH1,RNASEH2B,PARN,DCTPP1,PDE10A,UPF2,EXOSC4,ERI3,NT5M,CNOT4,PABPC1,DIS3L2,HSD17B14,NT5E,EXOSC2,WDR61,PDE4A,EIF4A2,DHX34,RNH1,EXOG,PDE2A,PDE3B,CTIF,POP1,CAT,KPNA1,RPL28,ZCCHC6,ATM,CNOT6,NCBP2,TATDN1,PDE9A,AGO3 |
| 2.943e-02 | -3.53 | Cellular Senescence | REACTOME pathways | R-HSA-2559583 | 187 | 35 | 8202 | 1117 |
HMGA2,EP400,TNIK,MINK1,ID1,UBN1,RING1,MAP2K3,PHC2,TERF2IP,ANAPC1,ACD,ANAPC11,ANAPC10,HIST2H3D,RNF2,CDK6,TERF2,KDM6B,CDK4,EHMT1,SCMH1,HIST1H2BL,HIST1H4J,UBE2E1,UBC,CDC16,EHMT2,H2AFX,ATM,BMI1,MAP2K4,AGO3,ANAPC4,TNRC6A |
| 2.943e-02 | -3.53 | oesophagus-carcinoma | COSMIC cancer mutations | oesophagus-carcinoma | 4462 | 609 | 17775 | 2278 |
ADAM19,DCP1B,NAT10,CACNA1H,SBF2,CSPP1,HLTF,CCNL2,HMOX2,SLC6A8,SYNJ1,NOS1AP,ZNF37A,PDZD2,SREBF2,ZFHX3,FAAH2,AP1M1,MAD1L1,PDS5B,HRG,SRRM2,FTSJ3,HMBOX1,NRAS,WLS,PTPRM,EHMT1,NFIA,KIF15,RFX2,C5AR1,MCL1,ABCC2,SLC7A1,AHNAK,BRCA2,LRRC40,BANP,HERC2,TRIP6,TRIO,NHS,BTBD9,CHN1,RBM20,DDX56,DHX37,KIAA1671,INTS7,MCM5,WDR60,GEMIN4,COQ3,MAP3K12,MYB,RABEPK,KLRD1,STAG1,ALG6,MYO10,RB1CC1,PRDM16,ARID5B,TYW1,RYR2,ST6GALNAC3,TRIM37,SRA1,USP46,NCDN,IRS1,DYNC1H1,VPS13C,TSR1,LRP1B,KPNA1,CLASRP,WDR33,MB21D2,ARHGAP10,ABCA3,DNM3,ZNF516,TRERF1,DDX18,NPAS2,BTBD2,PDK4,MYH9,NUP43,EEA1,STAM,RPGRIP1L,CD96,SPG21,ABCA12,SETD5,MMP14,TRMT12,ZC3H3,DENND1A,KMT2D,KRT7,ADAM32,PCNXL2,ATP6V0A1,TTC28,DSP,FGFR1,PDE8B,TAF2,KDM4B,NSMCE2,HIPK2,ARL13B,POLR3E,WDR7,FUS,ZBTB11,ANKS1A,CEP170,CATSPERG,TRIM36,XPC,C1orf226,WDR37,ATG2B,JMJD6,RSRC1,GATC,ACAP3,UNC13A,LTN1,C15orf41,SPTAN1,DIS3L2,DDHD1,FAM98A,POLK,ZC4H2,ZC3H18,CCDC113,CASC1,FOXC1,UBC,RARS,SRCAP,NSD1,BAZ2B,PXDN,POLE2,HERC1,SLCO5A1,SORCS2,DOCK6,GPATCH4,CUL7,RBM33,FAM13A,TTI1,SCAF8,BIRC2,MAP2K3,ECM1,SRSF2,DHX33,PHKA1,NCKIPSD,ANKRD11,HKR1,TRIML2,ETV1,MPST,PTPRK,VPS13B,FAM184A,FMNL3,CHD9,ABCC4,MIOS,ANK2,NOL6,PSMG1,LAMA2,KIF16B,BSN,GLS,HPRT1,LSS,TECPR2,RNF214,USP15,CHMP4C,LRRC28,FAN1,RLF,ARID1B,DNAH1,DOPEY1,RNFT2,ZNF358,ABCA5,CEP290,PDE10A,VPS72,SYNJ2,ALDH18A1,CWF19L2,NT5E,TRAPPC9,WARS2,LAMC1,USP49,HOMER2,SETD2,HAUS6,WDR25,OBSCN,ZNFX1,SUPT5H,NR2F1,FAM135A,SPAG9,PALB2,SYNCRIP,TTC38,DNAH17,TBPL1,PPP1R12B,CASS4,HMBS,DDX10,SH3PXD2A,USP7,MPI,CYLD,ARID2,SLC2A1,NTSR1,RSL1D1,ZNF83,DENND3,TNKS1BP1,PPP1R9A,ZNF121,URB1,DDX60L,PELP1,PLXNB1,CAD,ZNF608,ANKRD13A,JAG1,NUP133,UBR1,DNAJB6,FGGY,FSIP2,ANKRD24,ZFP37,MYH15,IPO11,TLCD1,EVL,GLTSCR2,KIRREL2,THSD4,CPOX,AKAP13,NHSL1,EIF3H,RBBP8,ZNF333,KLF4,CLEC16A,ITGA2,ATG7,PRRT3,AP2S1,PARD3,ESCO1,MAP3K13,RBM19,ZNF594,IQGAP2,SACS,ANXA7,CWC27,TMEM161A,PRICKLE2,SELT,HSD17B12,ADAMTSL3,LRRIQ1,TEX14,TOP3A,RAP1GDS1,PALLD,C8orf33,ARMC3,MKX,CACNB1,SRBD1,TAF4,TBX3,EIF2S1,USP20,TMEM219,RBM26,RBPJ,NR2F2,RPS6KC1,LMBRD2,ZNF292,LUZP1,PRKCSH,PRKAB2,NBEAL1,UBR5,MGA,PAK1IP1,ME1,CHD2,CSGALNACT2,TBC1D8,ZNF646,DDN,GDAP1,SETD1B,OSBP2,NOL8,TCEB3,SEMA3F,CAMSAP2,EFHC1,SON,FOXRED1,MAK16,PLCXD2,OSBPL1A,SH3GL1,SKIL,TRRAP,LSM14A,VPS13D,GREB1L,DNAH2,NRP1,RFXAP,SYNPO,SPOCK2,SPOCK3,DROSHA,ZHX3,ANKRD17,ST6GAL1,OPHN1,GTF2IRD1,PID1,PRPF39,TGFBR2,CD226,TECTA,NAV1,SLC7A11,SCAF1,LDOC1L,VWDE,CNOT4,SCAF11,SIK3,DDX28,PRIM2,AOC2,RABAC1,TPRA1,EHBP1,PLCB1,SLC26A11,ANGPTL4,CAT,ASCC3,EPRS,KIDINS220,VCAN,SRP68,SPEN,D2HGDH,SQLE,DPEP1,UMPS,IQSEC2,MACROD1,ZFHX2,CPT1C,TRPM2,SYT17,LIN28B,BIRC6,URB2,KIAA0232,SLC25A44,AP1B1,FLNB,IGSF1,FLAD1,CHD7,ZNF827,KDM2A,NBEA,PLEKHA4,NAA35,CASP8AP2,GON4L,MTIF2,PREX1,DLG4,SATB2,PNN,ZBTB25,DCBLD2,G6PD,LARGE,ACP1,TRMT2A,IFT140,MDN1,NCOR2,BRAF,NFX1,FARS2,LIAS,MLH1,MON2,IKBKAP,GDPD5,REEP5,NEDD4,ABL1,UPF2,CELF1,LARP4B,PLEKHG4,NAV3,FAM120B,FER1L5,SLC40A1,TTLL5,WDFY3,TMEM126B,KCNMA1,PACS1,MMAA,SLC23A2,ZFP62,ZDHHC11,ATM,MYOM2,APAF1,NDUFS5,BRWD3,PHF3,NF1,ATRX,KIF5A,ZNF107,BCOR,SMARCB1,PCYOX1L,WNT2B,MRPS30,ZNF804A,RTN1,YLPM1,THADA,ZNHIT6,MYH3,RELB,GPATCH1,ZEB1,HYAL1,POLR3B,TRIP13,CARM1,TIMM50,CEP128,ZBTB17,DEAF1,GPM6A,SLC38A1,ZNF680,LVRN,KSR2,HDAC8,SGK2,ZSCAN2,KMT2C,CDHR3,GEMIN5,TMEM132B,TMCO1,SUFU,TRMT5,DNAJC1,RLTPR,CSMD3,ABCC3,GALNT10,DMTF1,TNRC6A,SLC12A7,CHST11,AK2,FN1,TAF1,MED13L,QSER1,XPO7,CEP164,SIPA1L3,SEMA3D,GLTP,NRIP1,LRP3,MTHFD1,RANBP6,PPAT,ELP3,JMJD1C,WWC1,PRDM1,CORIN,DNAH14,EXOC6,POP1,SYCP2L,MYBBP1A,KIAA0754,FAT1,INTS5,SDCCAG8,EXOC4,FNBP1L,ZBTB24,DMXL2,ASH1L,PCNT,CELSR3,PSTPIP2,MYO7A,COBLL1,ARSJ,SLC9B2,PIBF1,GBF1,SBDS,ZC3H13,BRE,CAMTA2,SLC38A2,MET,HTRA2,AUP1,TMLHE,MAML3,NARS2,PRAME,COL5A2,PARP2,NLN,R3HDM1,ATXN1,TOR1AIP2,UBR4,TPK1,KPNA3,SCARB1,DISP1,HEATR1,RNF130,BRD9,SMG1,TNIK,SH2D3A,ARL15,PDE4B,CLSTN2,SEMA3E,SOGA1,ENOX1,SEC24C,DSG2,SHMT2,TTC17,FBL,DMRT1,PKNOX1,SLC25A1,TOP1,KDM6B,CRIM1,SCMH1,ARHGAP32,WDR35,CUL2,ZRANB2,MMP16,HRH1 |
| 2.947e-02 | -3.52 | PAS | prosite domains | PS50112 | 30 | 8 | 11866 | 1504 |
ARNTL2,HIF1A,NPAS2,PER1,ARNTL,KCNH3,KCNH2,PDE8B |
| 2.948e-02 | -3.52 | neural tube closure | biological process | GO:0001843 | 87 | 18 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SKI,APAF1,BMP4,PRKACB,MTHFD1 |
| 2.948e-02 | -3.52 | regulation of DNA binding | biological process | GO:0051101 | 87 | 18 | 16441 | 2138 |
HMGA2,ZNF675,ID1,MSX1,BRD4,ID2,RSF1,SIRT2,MAD2L2,KDM1A,SKI,DOT1L,MSX2,NSD1,ACD,HIPK2,ZFP90,DDIT3 |
| 2.949e-02 | -3.52 | actin filament-based process | biological process | GO:0030029 | 439 | 71 | 16441 | 2138 |
ARHGAP26,ACTG1,NF1,PAFAH1B1,PPARGC1B,ACTR3,MYO7A,TNXB,MYH9,COBLL1,ENAH,PLEK2,CORO6,RAC3,PPP1R9A,FLNB,ABL2,SHC1,DNAJB6,FMNL1,IKBKB,DTNBP1,MYH3,CORO1A,RAN,DBN1,FMNL3,EVL,LIMA1,PREX1,VIM,TMSB4X,CXADR,ARPC3,RHOU,CAMK2D,TPM1,PARD3,TNNC1,TTN,TNIK,SSH2,MINK1,CDC42EP2,OPHN1,ARFIP2,MON2,MAD2L2,SPIRE1,IQGAP2,ABL1,NEBL,TMSB10,NISCH,TTC17,AMOT,ACTR3B,FMNL2,MICAL3,PPP1R9B,TPM4,OBSCN,PALLD,ANXA1,INF2,FSCN1,FAT1,IQSEC2,FNBP1L,BRSK2,CORO2B |
| 2.955e-02 | -3.52 | human chr3p25.3 | chromosome location | human chr3p25.3 | 38 | 8 | 26250 | 2590 |
IL17RE,TADA3,RAD18,CAMK1,SETD5,IRAK2,ATG7,PRRT3 |
| 2.955e-02 | -3.52 | EIF4G3 (eukaryotic translation initiation factor 4 gamma, 3) | protein interactions | 8672 | 32 | 9 | 16036 | 2270 |
RBFOX2,CAMK1,SIRT7,EIF4A2,USP10,LIG4,PABPC1,EIF3H,PABPC4 |
| 2.955e-02 | -3.52 | RBM7 (RNA binding motif protein 7) | protein interactions | 10179 | 32 | 9 | 16036 | 2270 |
ZCCHC8,SKIV2L2,KHDRBS1,HAUS6,CCDC85B,SF3A3,SRRM2,SF3A1,CLK2 |
| 2.955e-02 | -3.52 | YTHDF2 (YTH N(6)-methyladenosine RNA binding protein 2) | protein interactions | 51441 | 32 | 9 | 16036 | 2270 |
SMAD3,FN1,RNF2,HMBS,BMI1,AGL,EIF3H,RPS6KB2,RPA1 |
| 2.955e-02 | -3.52 | ZNF622 (zinc finger protein 622) | protein interactions | 90441 | 32 | 9 | 16036 | 2270 |
POP1,ZNF622,G6PD,NOC3L,WDR33,RBM28,FTSJ3,LSG1,NMD3 |
| 2.955e-02 | -3.52 | DDX47 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 47) | protein interactions | 51202 | 32 | 9 | 16036 | 2270 |
CUL7,FN1,DDX18,WDR74,CBWD1,MLH1,EXOSC4,POLR1C,NOP58 |
| 2.956e-02 | -3.52 | temporal_lobe | COSMIC cancer mutations | temporal_lobe | 107 | 21 | 17775 | 2278 |
BRAF,NRAS,NF1,ATRX,PSPC1,KIAA0586,WWC1,RNF43,BCOR,MEN1,ZNF407,FGFR1,SMARCB1,AHNAK,HR,TRAP1,GREB1L,ANO8,MET,DCAF5,KIAA1549 |
| 2.958e-02 | -3.52 | actin filament binding | molecular function | GO:0051015 | 117 | 23 | 16491 | 2164 |
FLNC,TNNC1,PPP1R9B,TTN,SSFA2,MYO10,LIMA1,ACTR3,MYO7A,MAP1S,MYH9,CORO6,PPP1R9A,ARPC3,IQGAP2,ABL2,NEBL,FSCN1,FMNL1,MYH3,SVIL,CORO1A,CORO2B |
| 2.960e-02 | -3.52 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | 238 | 41 | 17758 | 2279 |
TTN,SPRED2,ADAM19,ATRX,TCF3,MED13L,BCOR,GAS6,ST3GAL6,LTB4R,C6orf48,JAG1,DNAJB6,MCM5,UBAP2L,KIAA0922,MAP3K14,MGLL,PKNOX1,SETD1B,HOMER2,MARCKSL1,MCL1,SON,HERPUD1,BATF3,VDR,GLS,SMARCC1,LMBR1L,RPL28,FSCN1,VCAN,ARL6IP5,RNF138,SQLE,ANXA2,RUNX1,DHCR7,TROVE2,LPP |
| 2.964e-02 | -3.52 | STEIN_ESR1_TARGETS | MSigDB lists | STEIN_ESR1_TARGETS | 82 | 17 | 17758 | 2279 |
CYP24A1,RFC4,MCM6,MCM10,GINS3,MED13L,MCM2,SACS,POLE2,KIDINS220,MCM5,NDRG4,SNX24,HSPB8,SLC16A1,GREB1,TMPO |
| 2.967e-02 | -3.52 | MIF4G-like_typ-3 | interpro domains | IPR003890 | 10 | 4 | 18293 | 2341 |
UPF2,MIF4GD,CTIF,NOM1 |
| 2.967e-02 | -3.52 | LUC7L (LUC7-like) | protein interactions | 55692 | 103 | 22 | 16036 | 2270 |
PRPF38B,ZCCHC8,TRA2A,SETD2,ZC3H18,CSNK2A1,JMJD6,PNN,DDX50,CTNNBL1,SYNCRIP,CLASRP,HNRNPR,LUC7L3,MRPS27,TNPO3,ZRANB2,RBM26,PRMT5,SRRM2,SRPK2,CLK2 |
| 2.967e-02 | -3.52 | HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3) | protein interactions | 220988 | 103 | 22 | 16036 | 2270 |
CHMP2A,CUL7,FN1,ITPA,RAB7A,SIRT7,HSPA5,HSD17B10,CYB5B,UBC,RAB10,PHF6,RPA1,SYNCRIP,HNRNPH3,COPS5,FDPS,CUL2,RNF2,FUS,SRRM2,TOP1 |
| 2.968e-02 | -3.52 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | 178 | 32 | 17758 | 2279 |
DNAJA4,EGR1,ID2,MYH9,WDR37,ST3GAL6,ARSJ,GIT2,SETD5,WAC,KDM5C,GMDS,SRRM2,ZMYM2,MBTPS2,PCSK6,NAV3,PDK1,WLS,JMJD1C,ARRDC3,ARHGAP32,ZNF467,CA5B,TMEM206,GATA6,RNF138,DISP1,RNF130,WDR33,NRP1,TNRC6A |
| 2.978e-02 | -3.51 | tube morphogenesis | biological process | GO:0035239 | 343 | 57 | 16441 | 2138 |
EFNB2,IFT57,DLL4,CELSR1,LUZP1,PAX2,MKS1,ID2,PBX1,ENAH,ZIC2,LIAS,SEMA3E,TGFBR2,SKI,CHD7,MYC,MMP14,NDRG4,TIMELESS,ZEB1,CCDC40,MET,CD44,PRKACB,MTHFD1,DEAF1,PXN,FGF2,FZD3,SETD2,RDH10,GRHL3,RYR2,ARID1A,MTHFD1L,SOX4,TCTN1,TCF7L2,GZF1,VDR,SMAD3,MSX2,GATA6,HIF1A,SDCCAG8,TBX3,ARL13B,BCAS3,RBPJ,BMP4,APAF1,NRP1,LAMA5,STK4,MEF2C,HS2ST1 |
| 2.978e-02 | -3.51 | macromolecule localization | biological process | GO:0033036 | 2012 | 289 | 16441 | 2138 |
THOC5,PRKAB2,DDX19A,PLRG1,NUP160,TOM1L1,EXOC1,RPS16,S100A10,AP1M1,VPS52,SEH1L,GDAP1,NRAS,OSBP2,ATG9A,WLS,EXOC6B,AP4B1,AKAP12,MCL1,ABCC2,ZDHHC14,OSBPL1A,STOML2,RBSN,VPS13D,FIS1,NRP1,NMD3,ZMAT3,BANP,HERC2,CELSR1,JUP,PRPF31,CCDC53,PRAF2,PIK3R4,SSR4,PITPNM1,ABCA7,IGF2BP3,TNPO3,IGF2BP1,TOMM34,TERF2,USE1,TIMM8B,EXOSC2,SYNGAP1,SIGMAR1,RAPGEF4,RYR2,CPT1A,ATP9B,IRS1,SEC31A,VPS13C,LRP1B,KPNA1,NME7,RPL28,NSF,UBAP1,SRP68,PEX13,KIAA0196,SRP14,SMYD3,COG5,ABCA3,PAFAH1B1,ATP6V1A,VTI1A,MYH9,NECAP1,NUP43,AP1B1,STAM,HNRNPA3,FLNB,TERF2IP,ACD,ABCA12,PPID,VGF,NBEA,ZC3H3,DENND1A,LYST,ASUN,WDPCP,DLG4,ATP6V0A1,DSP,ERC1,SERP1,VPS53,PES1,HLA-DMA,DNAJA3,IFT140,ANXA2,LAMA5,MID1,RAB30,BRAF,SCAMP3,TRAK1,KIF5C,GAS6,MON2,TGFB2,TMCO6,NEDD4,POM121,ABL1,TAF3,TRIAP1,PMPCA,UPF2,RDX,DYNC2H1,FGF9,CEP83,VPS37A,PACS1,NOP58,ANXA1,YIF1A,ZDHHC11,STX1A,STX18,GPAM,PSAP,BMP4,RABEP1,IPO4,IMMP2L,KIF5A,SEC16A,SRPRB,ABL2,RAP1A,SRSF2,ZNHIT6,ATG3,NCKIPSD,RAN,SLC27A5,TIMM50,PTPRK,CDC37,VPS13B,DBN1,MIOS,PPARG,ANK2,HSPA5,NOL6,COL4A3BP,SUMO3,PITPNB,CAV1,LSG1,TIMM44,PEX1,PAF1,EIF4ENIF1,TOM1L2,RLTPR,TNFRSF1A,BBIP1,ABCC3,CLU,C2CD5,CHMP4C,LDAH,CHST11,SEC24D,VTA1,STXBP6,NKD2,SMAD7,LAMTOR3,MAPK8IP3,SMG7,XPO7,TIMM10,RHBDD1,SPIRE1,DOPEY1,CEP290,ABCA5,ATXN2,PPIL2,GLTP,NRIP1,LRSAM1,ATP6V0D1,RANBP6,XPO5,OBSCN,MEX3B,AGAP1,TCF7L2,HERPUD1,EXOC6,BICD1,SNAP23,HK2,EXOC4,RRAGA,SNX24,SIL1,NAPA,TESC,CHMP2A,SNX27,ID1,OLFM2,RPS29,OSBPL9,MYO7A,PIBF1,RPAIN,GBF1,VPS18,GRIN2C,NUP133,DNAJB6,ZDHHC6,IKBKB,BCAP29,AHCYL1,CPSF3,VCL,TSPAN14,IPO11,AUP1,PRPF19,SEC24A,PHLDB2,RAB7A,TOR1AIP2,ATP8B2,NUP214,RAB10,PLIN2,RANBP2,KPNA3,TIMM17A,ATG7,NFASC,SCARB1,AP2S1,TSPAN5,SMG1,PARD3,TMEM33,TNIK,HM13,SUPT6H,VPS45,IGF2BP2,FOXP1,SLC25A20,PEX7,SEC24C,FBL,AMOT,MSX1,AP4S1,GPHN,MON1A,SCFD2,FERMT2,PDE2A,RERE,MFN2,CACNB1,WDR35,MPP7,VPS37B,NCBP2,RBPJ,NFKBIB,XPO6 |
| 2.981e-02 | -3.51 | parathyroid-hyperplasia | COSMIC cancer mutations | parathyroid-hyperplasia | 10 | 4 | 17775 | 2278 |
BRAF,NRAS,MEN1,CDC73 |
| 2.982e-02 | -3.51 | regulation of organ growth | biological process | GO:0046620 | 75 | 16 | 16441 | 2138 |
FGF9,FGF2,WWC1,PTK2,FLVCR1,SERP1,FOXC1,TCF7L2,FGFR1,GATA6,RBPJ,YBX3,FXN,CARM1,STK4,MEF2C |
| 2.982e-02 | -3.51 | regulation of chromosome segregation | biological process | GO:0051983 | 75 | 16 | 16441 | 2138 |
TEX14,CSNK2A1,HDAC8,SIRT2,MAD2L2,UBE2E1,KLHL22,ANAPC1,CDC16,RAD18,NSMCE2,ANAPC11,MAD1L1,ANAPC10,ATM,ANAPC4 |
| 2.987e-02 | -3.51 | AATGTGA,MIR-23A,MIR-23B | MSigDB lists | AATGTGA,MIR-23A,MIR-23B | 403 | 65 | 17758 | 2279 |
SNX27,ADAM19,DNM3,LIN28B,ADAMTS6,RNF43,SYNJ1,AMBRA1,CHD7,NEK6,GLYR1,SOCS6,ZEB1,KIAA0922,MET,ETV1,ZMYM2,TMPO,TNK2,NR6A1,VSNL1,AKAP12,MARCKSL1,ATXN1,SATB2,MAT2A,SMAD3,GLS,SLC7A1,TRMT5,HOXA3,MAGI1,TNRC6A,MEF2C,LPP,SSH2,AUH,PDE4B,TGFBR2,SLC1A1,POM121,MTUS1,ENTPD5,CFDP1,BUD31,PKNOX1,TOP1,ELOVL6,TEAD1,SETD2,RSBN1,PHACTR2,IL6R,PRDM1,PALLD,USP46,ZNF655,NAP1L5,KPNA1,UBAP2,WDR33,FNBP1L,SH3PXD2A,ARHGAP27,STK4 |
| 2.991e-02 | -3.51 | FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP | MSigDB lists | FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP | 58 | 13 | 17758 | 2279 |
ECM1,PSAT1,S100A10,PDLIM1,CA11,KLF4,VTI1A,DPP4,ABCC3,IGF2BP2,ETV1,VCL,TESC |
| 2.991e-02 | -3.51 | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | MSigDB lists | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | 58 | 13 | 17758 | 2279 |
IRS1,CYLD,TRAPPC9,PDK1,DNAJA3,TANK,RIPK1,ATM,FKBP5,MAP3K14,FOXO3,ERC1,CDC37 |
| 2.991e-02 | -3.51 | PID_FAK_PATHWAY | MSigDB lists | PID_FAK_PATHWAY | 58 | 13 | 17758 | 2279 |
ARHGAP26,RAP1A,PXN,BRAF,ASAP1,RAP1B,MAPK8IP3,MMP14,PTK2,VCL,MAP2K4,GIT2,SH3GL1 |
| 2.995e-02 | -3.51 | STARK_BRAIN_22Q11_DELETION | MSigDB lists | STARK_BRAIN_22Q11_DELETION | 10 | 4 | 17758 | 2279 |
USP7,CLEC16A,BSN,TRAK1 |
| 2.995e-02 | -3.51 | NUCLEAR_SPECK | MSigDB lists | NUCLEAR_SPECK | 10 | 4 | 17758 | 2279 |
NSRP1,PRPF31,TFIP11,TIMM50 |
| 2.995e-02 | -3.51 | HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS | MSigDB lists | HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS | 10 | 4 | 17758 | 2279 |
APEX1,OGG1,MUTYH,MSH3 |
| 2.995e-02 | -3.51 | RNA_ELONGATION | MSigDB lists | RNA_ELONGATION | 10 | 4 | 17758 | 2279 |
ELL,SUPT4H1,SUPT5H,CDK9 |
| 2.995e-02 | -3.51 | ANTIPORTER_ACTIVITY | MSigDB lists | ANTIPORTER_ACTIVITY | 10 | 4 | 17758 | 2279 |
SLC25A11,SLC3A2,SLC7A11,SLC9A5 |
| 2.995e-02 | -3.51 | EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX | MSigDB lists | EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX | 10 | 4 | 17758 | 2279 |
EIF3C,COPS5,EIF3J,EIF3H |
| 2.995e-02 | -3.51 | TRNA_PROCESSING | MSigDB lists | TRNA_PROCESSING | 10 | 4 | 17758 | 2279 |
FARS2,METTL1,SARS,AARS |
| 2.995e-02 | -3.51 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | MSigDB lists | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | 10 | 4 | 17758 | 2279 |
POLB,APEX1,OGG1,MUTYH |
| 2.996e-02 | -3.51 | regulation of molecular function | biological process | GO:0065009 | 2753 | 389 | 16441 | 2138 |
ARHGAP26,DCP1B,PRKAB2,SBF2,CCNL2,PRKCA,LPAR3,AMBRA1,NOS1AP,SKI,GIPR,TOM1L1,S100A10,PMAIP1,ZFYVE28,RABGAP1L,MAD1L1,HRG,FXN,TBC1D8,NRAS,C5AR1,DCUN1D5,DENND4A,SPOP,DOT1L,DDX3X,DDAH2,AHNAK,CCNT1,SH3RF1,ARL6IP5,FIS1,DIRAS1,TPM1,NRP1,TNFRSF10D,BMI1,SPOCK3,P2RY11,MEF2C,HERC2,TNNC1,EPM2AIP1,IFT57,CDC42EP2,JUP,SLK,TRIO,OPHN1,PIK3R4,CRACR2A,RSF1,TGFBR2,PDCD5,ABCA7,PRKCE,FKBP1A,CHN1,CNST,HR,ASAP1,CACNB2,MYC,ANP32B,MAP3K12,CAV2,TERF2,HMGCR,ADARB1,PEA15,ZNF675,BDNF,SYNGAP1,ARID5B,EIF4A2,RAPGEF4,RAP1GAP2,RYR2,SMARCD3,ARRDC4,EVI5,PLCB1,TRIM37,SRA1,ANGPTL4,IRS1,CAT,KIDINS220,HIF1A,CDK9,DPEP1,CNOT6,IQSEC2,ARHGAP10,SMYD3,SGSM3,SPRED2,MAP2K5,BIRC6,PAFAH1B1,DDR2,AGAP6,HSPA1A,RING1,TERF2IP,SLX4,SHC1,ACD,TBC1D22A,UCHL5,SOCS6,MMP14,DTNBP1,SSBP1,SERPINH1,PXK,KMT2A,DENND1A,CDK12,PERP,CASP8AP2,BRD4,ARHGEF10,PREX1,DLG4,MED16,TBC1D16,STK10,ERC1,FGFR1,SNCA,VDR,MSX2,ARHGAP21,CAMK2D,CDC16,HIPK2,DNAJA3,TRAF3,ANXA2,BRCC3,TBXA2R,XRCC4,SETD6,HMGA2,NOSTRIN,SERINC5,BRAF,TCF3,ID2,RCAN1,GAS6,MON2,AKT1S1,TRIM22,BHLHE40,IKBKAP,NOL3,TGFB2,RPS6KA5,PSMF1,MAD2L2,NEDD4,ABL1,NPRL2,RGS17,TAF3,ACAP3,TRIAP1,ANXA5,RAPGEFL1,ARHGAP1,RDX,NLGN3,ERRFI1,MAP3K14,PLEKHG4,SPTAN1,MBTPS2,FGF9,PXN,ZFYVE1,PACS1,PTK2,IL6R,UBC,ANXA1,OXSR1,TRIB3,KLHL22,NSD1,HERC1,ATM,APAF1,PSAP,BMP4,PGAM5,IGBP1,RABEP1,DOCK6,ANAPC4,DDIT3,KAT6A,STK4,UBN1,NF1,PPARGC1B,PTPRA,CSNK2A1,SIRT2,FAM13A,NLE1,BIRC2,GIT2,MAP2K3,SMARCB1,ABL2,ANAPC1,ECM1,RAP1A,ARHGAP18,CNIH3,GPR87,ANAPC11,ANAPC10,PCOLCE2,RAN,CARM1,PRKACB,TRIM14,CDC37,TNK2,TRIM13,RBCK1,SESN2,PPARG,ANK2,CDK4,TFPI,ARRDC3,HSPA5,GMFB,CAV1,SGK2,SERGEF,ZNF622,SUFU,TP53BP1,DNAJC1,SOCS4,CTAGE5,ADAM9,SGSM2,CLU,MTCH1,TTN,FN1,PAX2,UBXN1,SMAD7,LAMTOR3,MAPK8IP3,TRIM15,ZIC2,ELL,SIPA1L3,BUD31,GTF2H1,VAPB,CAMKK2,CRADD,ELP3,OBSCN,PSMA1,RNH1,MEX3B,AGAP1,HERPUD1,VAC14,UBE2E1,TCF7L2,TBC1D2,SPAG9,BICD1,IRAK2,PPP1R12B,SIL1,ARHGAP12,ZFP90,BRSK2,PRKAR2A,TESC,BCCIP,USP7,ID1,CYLD,CEMIP,NTSR1,TNXB,PPP2R2A,SMARCA4,PBX1,RIPK1,DENND3,CSTA,PIBF1,GBF1,PLXNB1,KDM1A,MPHOSPH10,SOCS1,NVL,GRIN2C,DNAJB6,IKBKB,RNF2,AHCYL1,CASP10,HTRA2,AUP1,CTC1,TMLHE,ARHGAP17,GRHL3,TOR1AIP2,AKAP13,DKC1,ZC3H12A,SMAD3,RANBP2,ADNP,KLF4,DUSP19,SCARB1,ARC,EIF2B3,PKIB,KLHL24,TNIK,NIFK,MINK1,SH2D3A,MAP3K13,CAMK1,PDE4B,DBF4,CHCHD10,PPP1R1C,CSNK1A1,SFI1,ANKRD54,IQGAP2,PTPN2,PRKCH,SCN1B,FBXO31,CD44,AMOT,PPP1R9B,DNMBP,MSX1,FGF2,CRIM1,KDM5A,ASAP3,TEX14,RAP1GDS1,ARHGEF12,RANGAP1,PHACTR2,ARHGAP32,MEN1,PIK3CB,HSPA1B,CACNB1,SERINC1,GADD45A,SET,MSH3,BCAS3,RBM26,TAF12,NFKBIB,NR2F2,ZAK,MMP16,ARHGAP27,HRH1 |
| 2.997e-02 | -3.51 | lipid modification | biological process | GO:0030258 | 150 | 28 | 16441 | 2138 |
MCEE,ACADS,SESN2,PPARG,PI4KAP2,PCCA,IP6K2,INPP1,SYNJ1,CPT1A,ACOXL,PIK3CB,PIP4K2A,MMAA,ETFB,ECH1,DECR1,PEX7,ETFDH,PI4KB,ACOX1,BDH2,PEX13,SYNJ2,BPNT1,MTMR1,SMG1,CPT1C |
| 3.001e-02 | -3.51 | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 165 | 30 | 17758 | 2279 |
CTU2,SERINC5,PXN,TFIP11,GPCPD1,SIRT7,TMEM183A,TCEB3,UTP15,NOL6,ID2,EFHC1,BTBD9,BCOR,C1orf52,RBM19,ARIH2,ANXA1,VPS18,ARHGAP21,IKZF5,L3MBTL3,ZNF326,JOSD1,RPS6KB1,TBL1X,TTC17,POLR1C,SOX6,SF3A1 |
| 3.010e-02 | -3.50 | RBBP4 (retinoblastoma binding protein 4) | protein interactions | 5928 | 168 | 33 | 16036 | 2270 |
CUL7,CUL4A,FN1,ATP6V1A,SIRT7,CSNK2A1,SMARCA4,HMOX2,CHD5,KDM1A,SMARCB1,ANXA7,MBD2,BANF1,RNF2,SRRM2,SAP30,GATAD2B,AEBP2,KDM5B,SIRT6,GNL3,BRCA1,PHF6,ISG15,UBC,CHAF1A,BAZ1A,CHD3,SPEN,NCOR1,FUS,RBP1 |
| 3.011e-02 | -3.50 | WILCOX_RESPONSE_TO_PROGESTERONE_UP | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_UP | 139 | 26 | 17758 | 2279 |
KLHL24,FADS1,MVK,ELOVL6,TBCCD1,WDHD1,ATG2B,MON2,GALK2,NUP160,CYB5B,KLF6,SMPDL3B,LPIN1,LSS,ZBED2,IDI1,INSIG1,FDPS,PEG10,DHCR7,XRCC4,ETV1,FDFT1,PCSK6,HMGCR |
| 3.016e-02 | -3.50 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | 279 | 47 | 17758 | 2279 |
EFNB2,FN1,RBFOX2,DBF4,ID2,QSER1,IKBIP,CHN1,ADH5,GART,SOCS1,ASAP1,PMAIP1,ERI1,RAN,CEP135,FMNL2,ANGPT2,TMEM200A,TMPO,PMS1,RFC3,LAMC1,ERICH1,ZNF195,COL5A2,FGF2,KCNMA1,HAUS6,KIF15,WDHD1,SOX4,DDX60,FLVCR1,MTR,OSBPL1A,GLS,SLC39A14,ASCC3,C6orf141,RBBP8,POLE2,GATA6,VCAN,MBTD1,FKBP5,VASH2 |
| 3.017e-02 | -3.50 | MORF_DDX11 | MSigDB lists | MORF_DDX11 | 152 | 28 | 17758 | 2279 |
KAT8,SIK3,GTF2H3,MSX1,SETD1B,PRKCSH,LSM12,FAM189B,SFSWAP,TRA2A,SLC2A1,KLHL18,CSNK2A1,TTI1,EIF5B,PITPNM1,HTR7,RANBP2,SLC30A3,RBBP8,CHD3,PPIL2,NCKIPSD,IFT140,CRCP,SLC25A11,NFRKB,RPS6KB2 |
| 3.017e-02 | -3.50 | ubiquitin-like protein binding | molecular function | GO:0032182 | 111 | 22 | 16491 | 2164 |
HERC2,DNAJC2,RBCK1,UBXN1,FAN1,DCUN1D5,SIRT2,UBR5,NEDD4,ZRANB3,TOM1L1,SMAD3,BRE,RAD18,USPL1,UBAP1,RNF111,ATRIP,BRCC3,AGL,AUP1,CASP8AP2 |
| 3.018e-02 | -3.50 | protein complex biogenesis | biological process | GO:0070271 | 1042 | 156 | 16441 | 2138 |
IMMP2L,UBN1,ATRX,AARS2,TRPM6,SBF2,SIRT2,COA1,SEC16A,COX10,SYNJ1,BIRC2,CUTC,SKI,NEK6,S100A10,CNIH3,ZNHIT6,WIZ,ME1,LONP1,ACADS,SKAP2,PSMG1,HIST1H2BL,CAV1,MCM2,FOXRED1,MGST1,CHAF1A,STOML2,GEMIN5,GLS,SKIL,HPRT1,AHNAK,TNFRSF1A,FIS1,CLU,MAGI1,UQCC2,TTN,FN1,SEC24D,HSD17B10,RSF1,DNAH1,SLC1A1,NDUFS7,FKBP1A,HR,MBD2,MED24,ANP32B,CCDC88C,PRF1,CAV2,HMGCR,RANBP6,TRAPPC9,LAMC1,TSPYL4,PPAT,HAUS6,BCS1L,SNAP25,IMPDH2,TRAPPC6B,SYT1,CPT1A,ANGPTL4,NAP1L5,CAT,SEC31A,EPRS,SPAG9,NSF,SNAP23,SURF1,KIAA0196,NCOR1,NAPA,SMYD3,PDSS2,VMA21,KCTD7,CHMP2A,CYLD,SLC2A1,C1QTNF7,COBLL1,RIPK1,PIBF1,BLOC1S2,NUBPL,DECR1,KCTD11,PPID,CBR4,CCDC40,CEP63,TMEM120B,KMT2A,SEC24A,EVL,MPP6,C1QTNF1,PREX1,ARHGEF10,DLG4,ATP6V0A1,HLA-DMA,SMAD3,ARMC4,CAMK2D,KPNA3,ALAD,DCXR,H2AFX,MDN1,ANXA2,AP2S1,PARD3,TMEM33,NIFK,BRAF,HM13,C10orf2,TRIM22,MLH1,NOL3,IKBKAP,POGZ,DCTPP1,PSMG4,SEC24C,HIST2H3D,ANXA5,SHMT2,TTC17,PXN,SMARCAD1,KCNMA1,FERMT2,ADSL,HIST1H4J,PTK2,UBE2K,CENPP,SET,NDUFAF5,NDUFS5,APAF1,UQCC1,IPO4,KAT6A |
| 3.018e-02 | -3.50 | protein complex assembly | biological process | GO:0006461 | 1042 | 156 | 16441 | 2138 |
IMMP2L,UBN1,ATRX,AARS2,TRPM6,SBF2,SIRT2,COA1,SEC16A,COX10,SYNJ1,BIRC2,CUTC,SKI,NEK6,S100A10,CNIH3,ZNHIT6,WIZ,ME1,LONP1,ACADS,SKAP2,PSMG1,HIST1H2BL,CAV1,MCM2,FOXRED1,MGST1,CHAF1A,STOML2,GEMIN5,GLS,SKIL,HPRT1,AHNAK,TNFRSF1A,FIS1,CLU,MAGI1,UQCC2,TTN,FN1,SEC24D,HSD17B10,RSF1,DNAH1,SLC1A1,NDUFS7,FKBP1A,HR,MBD2,MED24,ANP32B,CCDC88C,PRF1,CAV2,HMGCR,RANBP6,TRAPPC9,LAMC1,TSPYL4,PPAT,HAUS6,BCS1L,SNAP25,IMPDH2,TRAPPC6B,SYT1,CPT1A,ANGPTL4,NAP1L5,SEC31A,CAT,EPRS,SPAG9,NSF,SNAP23,SURF1,KIAA0196,NCOR1,NAPA,SMYD3,PDSS2,VMA21,KCTD7,CHMP2A,CYLD,SLC2A1,C1QTNF7,COBLL1,RIPK1,PIBF1,BLOC1S2,NUBPL,DECR1,KCTD11,PPID,CBR4,CCDC40,CEP63,TMEM120B,KMT2A,SEC24A,EVL,MPP6,C1QTNF1,PREX1,ARHGEF10,DLG4,ATP6V0A1,HLA-DMA,SMAD3,ARMC4,CAMK2D,KPNA3,ALAD,DCXR,H2AFX,MDN1,ANXA2,AP2S1,PARD3,TMEM33,NIFK,BRAF,HM13,C10orf2,TRIM22,MLH1,NOL3,IKBKAP,POGZ,DCTPP1,PSMG4,SEC24C,HIST2H3D,ANXA5,SHMT2,TTC17,PXN,SMARCAD1,KCNMA1,FERMT2,ADSL,HIST1H4J,PTK2,UBE2K,CENPP,SET,NDUFAF5,NDUFS5,APAF1,UQCC1,IPO4,KAT6A |
| 3.018e-02 | -3.50 | ELVIDGE_HIF1A_TARGETS_UP | MSigDB lists | ELVIDGE_HIF1A_TARGETS_UP | 64 | 14 | 17758 | 2279 |
SRM,SOBP,KPNA1,LARS2,URB2,ABCF2,GLYR1,SLC29A1,CORO1A,GYG1,SLC25A44,LSG1,TMEM33,TAF9B |
| 3.019e-02 | -3.50 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | MSigDB lists | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | 70 | 15 | 17758 | 2279 |
NCOR2,PPARG,KLF4,CDK4,MED27,MED13L,SMARCD3,MED24,MED18,MED16,TBL1X,MED20,NCOR1,NR2F2,ANGPTL4 |
| 3.019e-02 | -3.50 | AGTCTTA,MIR-499 | MSigDB lists | AGTCTTA,MIR-499 | 70 | 15 | 17758 | 2279 |
AEBP2,PTBP2,LIN28B,KPNA3,UBN1,ARID2,HIC2,ARHGAP12,RSBN1,ZNF518B,SOX6,UBE2E1,ZNF655,TOP1,MYB |
| 3.020e-02 | -3.50 | human chr17q25.3 | chromosome location | human chr17q25.3 | 98 | 16 | 26250 | 2590 |
CCDC57,TEX19,OXLD1,C1QTNF1,TBC1D16,RAC3,SLC26A11,USP36,PYCR1,DCXR,SYNGR2,ANAPC11,DNAH17,SLC25A19,CCDC40,B3GNTL1 |
| 3.021e-02 | -3.50 | MCM_1 | prosite domains | PS00847 | 6 | 3 | 11866 | 1504 |
MCM6,MCM2,MCM5 |
| 3.021e-02 | -3.50 | FATC | prosite domains | PS51190 | 6 | 3 | 11866 | 1504 |
ATM,TRRAP,SMG1 |
| 3.021e-02 | -3.50 | FAT | prosite domains | PS51189 | 6 | 3 | 11866 | 1504 |
ATM,TRRAP,SMG1 |
| 3.024e-02 | -3.50 | neuron migration | biological process | GO:0001764 | 112 | 22 | 16441 | 2138 |
FBXO45,GPM6A,PCNT,CELSR1,CELSR3,PAFAH1B1,FZD3,ELP3,SATB2,GAS6,PTK2,FGFR1,NR2F1,DDIT4,PEX7,NAV1,SDCCAG8,PEX13,NR2F2,NRP1,MAPT,MEF2C |
| 3.026e-02 | -3.50 | cAMP binding | molecular function | GO:0030552 | 24 | 7 | 16491 | 2164 |
PDE2A,PDE4A,PDE10A,PRKAR2A,RAPGEF4,PDE3A,PDE4B |
| 3.027e-02 | -3.50 | human chr19p13.2 | chromosome location | human chr19p13.2 | 188 | 27 | 26250 | 2590 |
OLFM2,PDE4A,ZNF414,PRKCSH,C19orf43,MRI1,SMARCA4,ZNF709,ZNF44,TIMM44,KRI1,FARSA,ZNF358,ZNF266,ZNF561,YIPF2,PLPPR2,ZNF557,ZNF561-AS1,DOCK6,HNRNPM,CARM1,LONP1,CTXN1,P2RY11,CDC37,ELOF1 |
| 3.034e-02 | -3.50 | ALYREF (Aly/REF export factor) | protein interactions | 10189 | 109 | 23 | 16036 | 2270 |
SKIV2L,THOC5,CUL7,FN1,TLE3,SIRT7,GNL1,PABPC4,UBC,ZC3H13,DOT1L,DDX3X,SRSF2,WDR35,COPS5,CUL2,H2AFX,RNF2,PXK,SRRM2,PABPC1,TRIP13,HNRNPM |
| 3.037e-02 | -3.49 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III | 120 | 23 | 17775 | 2278 |
SCAF11,ASH1L,BRAF,NRAS,LARS2,ATRX,PPP1R21,RYR2,RCAN1,DENND3,DSP,TMCO6,PCDH7,SMARCB1,TBC1D2,TP53BP1,ZKSCAN1,ATM,CSMD3,NFKBIB,ZBTB11,AMOT,AVEN |
| 3.043e-02 | -3.49 | nuclear periphery | cellular component | GO:0034399 | 121 | 23 | 17570 | 2233 |
RANBP6,NCOR2,ATF4,AKAP8L,POLA1,PSPC1,SMARCAD1,ATXN1,SATB2,ENC1,MEN1,SCAF8,CAD,SNW1,ATXN7,PHF5A,HLCS,ZNF326,OGG1,HNRNPM,MAPT,IPO4,MYB |
| 3.044e-02 | -3.49 | telosome | cellular component | GO:0070187 | 6 | 3 | 17570 | 2233 |
TERF2IP,ACD,TERF2 |
| 3.044e-02 | -3.49 | pre-snoRNP complex | cellular component | GO:0070761 | 6 | 3 | 17570 | 2233 |
NOP58,ZNHIT6,NOP56 |
| 3.046e-02 | -3.49 | tRNA processing in the nucleus | REACTOME pathways | R-HSA-6784531 | 55 | 13 | 8202 | 1117 |
RPP30,POP1,RANBP2,ZBTB8OS,NUP133,RAN,NUP43,POP5,TSEN2,NUP160,NUP214,POM121,SEH1L |
| 3.048e-02 | -3.49 | V$AP1_Q4_01 | MSigDB lists | V$AP1_Q4_01 | 252 | 43 | 17758 | 2279 |
RELL2,SSH2,SEC24D,FAM46B,TNXB,SPATS2,FAM49A,PHLDA2,TTC1,ZNF827,ECM1,SRSF2,ANXA7,ADCK4,SRPK2,MYB,FAM184A,PEA15,PPP1R9B,NRAS,LAMC1,WDFY3,RB1CC1,BAZ2A,PRDM1,NCDN,GNAI1,YIF1A,VDR,DYNC1H1,TSR1,GADD45A,HSPB8,MPV17,ZNF436,CSMD3,TRAF3,DIRAS1,RBPJ,ITGB4,BLMH,SYNPO,DDIT3 |
| 3.051e-02 | -3.49 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | 185 | 33 | 17758 | 2279 |
SRM,FBXO45,MVK,RSL1D1,RTN4,TMEM132A,ETFB,PHF5A,MCM5,CCDC40,ETF1,YARS,SEH1L,HNRNPM,TMPO,FDFT1,GTF2H3,RFC4,PTBP2,POLA1,STOML2,EXO1,SLC7A1,KPNA3,BIVM,SVIL,EIF2S1,PTRH2,HMBS,PREPL,TSEN2,ADK,IPO4 |
| 3.058e-02 | -3.49 | O-acyltransferase activity | molecular function | GO:0008374 | 40 | 10 | 16491 | 2164 |
LPCAT2,AGPAT4,GPAT3,LPCAT3,GPAM,PNPLA3,LCLAT1,CPT1A,LPCAT1,CPT1C |
| 3.063e-02 | -3.49 | PAFAH1B2 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)) | protein interactions | 5049 | 53 | 13 | 16036 | 2270 |
TPD52L2,FN1,GINS3,TRIP6,PAFAH1B1,PSMG1,RAP1GDS1,SHMT2,ZFP36L1,VARS,TATDN1,BZW2,TIMM50 |
| 3.063e-02 | -3.49 | TUBB6 (tubulin, beta 6 class V) | protein interactions | 84617 | 53 | 13 | 16036 | 2270 |
SEC24A,CUL7,DNAJA4,SHC1,TUBA1A,PSAT1,FN1,CAMKMT,METTL23,CLU,AHCYL1,HTRA2,RPS6KB2 |
| 3.063e-02 | -3.49 | TGOLN2 (trans-golgi network protein 2) | protein interactions | 10618 | 53 | 13 | 16036 | 2270 |
PPP1R9B,LARS2,NF1,INTS5,AP1M1,PDS5B,C16orf58,LTN1,INTS12,MDN1,HEATR1,PPP1R9A,HS2ST1 |
| 3.070e-02 | -3.48 | Polycystic ovary syndrome(PMID:21151128) | GWAS genes | Polycystic ovary syndrome(PMID:21151128) | 2 | 2 | 2389 | 419 |
THADA,DENND1A |
| 3.070e-02 | -3.48 | Diabetes (gestational)(PMID:22233651) | GWAS genes | Diabetes (gestational)(PMID:22233651) | 2 | 2 | 2389 | 419 |
CDKAL1,IGF2BP2 |
| 3.070e-02 | -3.48 | Kawasaki disease(PMID:19132087) | GWAS genes | Kawasaki disease(PMID:19132087) | 2 | 2 | 2389 | 419 |
ZFHX3,NAALADL2 |
| 3.070e-02 | -3.48 | Colorectal cancer(PMID:20972440) | GWAS genes | Colorectal cancer(PMID:20972440) | 2 | 2 | 2389 | 419 |
MYNN,LAMA5 |
| 3.070e-02 | -3.48 | Coronary heart disease(PMID:22319020) | GWAS genes | Coronary heart disease(PMID:22319020) | 2 | 2 | 2389 | 419 |
IL6R,FN1 |
| 3.070e-02 | -3.48 | Brain imaging in schizophrenia (interaction)(PMID:19023125) | GWAS genes | Brain imaging in schizophrenia (interaction)(PMID:19023125) | 2 | 2 | 2389 | 419 |
TNIK,TRAF3 |
| 3.070e-02 | -3.48 | Alcoholism (alcohol dependence factor score)(PMID:21529783) | GWAS genes | Alcoholism (alcohol dependence factor score)(PMID:21529783) | 2 | 2 | 2389 | 419 |
MBNL2,ANKS1A |
| 3.070e-02 | -3.48 | Chronic obstructive pulmonary disease(PMID:20173748) | GWAS genes | Chronic obstructive pulmonary disease(PMID:20173748) | 2 | 2 | 2389 | 419 |
IREB2,FAM13A |
| 3.070e-02 | -3.48 | Male infertility(PMID:19478329) | GWAS genes | Male infertility(PMID:19478329) | 2 | 2 | 2389 | 419 |
CRACR2A,PDE3A |
| 3.073e-02 | -3.48 | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | 293 | 49 | 17758 | 2279 |
EFNB2,HM13,POLR1A,C1orf52,SLC9B2,C11orf54,MGA,SKI,KCTD11,ZNF354A,ZKSCAN1,NSRP1,SYN2,DSG2,CCDC112,NBEA,SLC16A9,MET,HN1,PAQR6,ADARB1,FAM71E1,GDAP1,KRT7,LAMC1,IFT43,PPAT,CRIM1,FOXN3,PRDM16,ARHGEF10,ATXN1,PRDM1,LENG8,ZNF467,VDR,GLS,TCF7L1,EIF4ENIF1,SIX5,LARGE,PRRT3,SYNPO,DCAF5,SMYD3,LAMA5,MAPT,RBP1,LPP |
| 3.079e-02 | -3.48 | response to antibiotic | biological process | GO:0046677 | 46 | 11 | 16441 | 2138 |
SKIL,AOC3,HYAL3,EGR1,HSPA5,HYAL1,HMBS,ZC3H8,RSRC1,RAB10,MEF2C |
| 3.080e-02 | -3.48 | HSPB1 (heat shock 27kDa protein 1) | protein interactions | 3315 | 392 | 69 | 16036 | 2270 |
THOC5,LUZP1,PRDX6,ZBTB37,PTPRA,OSBPL9,OLA1,SMARCA4,ISG20L2,FLNB,NVL,KANSL1,UCHL5,IKBKB,NCKIPSD,TTC3,CPSF3,SRRM2,HN1,PRPF19,ZBTB17,GARS,ITPA,MTIF2,HSPA5,VIM,PITPNB,CCNDBP1,ZNF197,SNCA,PAF1,AHNAK,KPNA3,G6PD,COPS5,HSPB8,WDR66,UQCC2,SARS,MCM6,FN1,CCDC53,CAMK1,SF3A3,RPS6KA5,C15orf57,NAMPT,TOX4,SNW1,MYC,ATIC,PPA1,PSAT1,EIF4A2,SUPT5H,PALLD,TARS,ISG15,UBC,ANXA1,RPA1,PDLIM1,HNRNPH3,EIF2S1,RBPJ,PFDN2,IGBP1,NAPA,RNF114 |
| 3.080e-02 | -3.48 | V$GATA2_01 | MSigDB lists | V$GATA2_01 | 101 | 20 | 17758 | 2279 |
RELL2,DPF3,SHQ1,PAFAH1B1,TRA2A,NFIA,PPP2R2A,ST7L,SYMPK,PHF6,NCDN,SPOP,UBTF,TCF7L1,SRSF2,SYNCRIP,MPV17,AMOT,MAML3,ATXN7L2 |
| 3.080e-02 | -3.48 | GGAANCGGAANY_UNKNOWN | MSigDB lists | GGAANCGGAANY_UNKNOWN | 101 | 20 | 17758 | 2279 |
CHMP2A,SUPT6H,C10orf2,UBXN1,BMS1,SLC25A44,UBL5,EIF3H,FARSA,TMCO1,RARS,CNST,RPL28,E2F4,SEC24C,BANF1,EIF2S1,NCBP2,TTC17,MRPL21 |
| 3.090e-02 | -3.48 | P4HB (prolyl 4-hydroxylase, beta polypeptide) | protein interactions | 5034 | 115 | 24 | 16036 | 2270 |
ZNF292,CUL7,TRIP6,PRKCSH,SIRT7,AGO2,HSPA5,EIF4A2,HSD17B10,CLNS1A,PGD,PRPF40B,TPD52L2,P3H1,CUL2,H2AFX,EIF2S1,RDX,BCAP29,RNF2,PFDN2,SERPINH1,BMI1,PABPC1 |
| 3.092e-02 | -3.48 | HNF4A (hepatocyte nuclear factor 4, alpha) | protein interactions | 3172 | 75 | 17 | 16036 | 2270 |
NCOR2,FOXO1,PPARGC1B,ELP3,SMARCA4,MED16,PABPC4,NR2F1,VDR,SMAD3,SUB1,SREBF2,COPS5,GTF2H1,MED24,ANP32B,NRIP1 |
| 3.092e-02 | -3.48 | SERBP1 (SERPINE1 mRNA binding protein 1) | protein interactions | 26135 | 75 | 17 | 16036 | 2270 |
GARS,ITFG1,SIRT7,RPS29,CSNK2A1,VIM,EIF2A,ISG15,DYNC1H1,TSR1,CHD3,HNRNPR,UPF2,FUS,PABPC1,SERBP1,RPS6KB2 |
| 3.095e-02 | -3.48 | histone acetylation | biological process | GO:0016573 | 106 | 21 | 16441 | 2138 |
KAT8,WDR75,EP400,BRD4,TRIM16,TAF1,TCF3,ELP3,CHD5,TADA3,SRCAP,BRCA2,TRRAP,KANSL1,PER1,MED24,TAF12,POLE3,KMT2A,YEATS2,KAT6A |
| 3.101e-02 | -3.47 | Exportin-1/Importin-b-like | interpro domains | IPR013598 | 6 | 3 | 18293 | 2341 |
TNPO3,XPO6,XPO5 |
| 3.101e-02 | -3.47 | Znf_Sec23_Sec24 | interpro domains | IPR006895 | 6 | 3 | 18293 | 2341 |
SEC24A,SEC24D,SEC24C |
| 3.101e-02 | -3.47 | Sec23/24_trunk_dom | interpro domains | IPR006896 | 6 | 3 | 18293 | 2341 |
SEC24A,SEC24D,SEC24C |
| 3.101e-02 | -3.47 | MCM_CS | interpro domains | IPR018525 | 6 | 3 | 18293 | 2341 |
MCM6,MCM2,MCM5 |
| 3.101e-02 | -3.47 | Beta2_adaptin/TBP_C_dom | interpro domains | IPR012295 | 6 | 3 | 18293 | 2341 |
AP1B1,AP4B1,TBPL1 |
| 3.101e-02 | -3.47 | tRNA_SAD | interpro domains | IPR012947 | 6 | 3 | 18293 | 2341 |
AARS,TARS,AARS2 |
| 3.101e-02 | -3.47 | Sec23/24_helical_dom | interpro domains | IPR006900 | 6 | 3 | 18293 | 2341 |
SEC24A,SEC24D,SEC24C |
| 3.101e-02 | -3.47 | PIK_FAT | interpro domains | IPR014009 | 6 | 3 | 18293 | 2341 |
ATM,TRRAP,SMG1 |
| 3.101e-02 | -3.47 | Sec23_24_beta_S | interpro domains | IPR012990 | 6 | 3 | 18293 | 2341 |
SEC24A,SEC24D,SEC24C |
| 3.101e-02 | -3.47 | LNS2/PITP | interpro domains | IPR031315 | 6 | 3 | 18293 | 2341 |
PITPNM1,LPIN2,LPIN1 |
| 3.101e-02 | -3.47 | MCM_N | interpro domains | IPR027925 | 6 | 3 | 18293 | 2341 |
MCM6,MCM2,MCM5 |
| 3.101e-02 | -3.47 | TIF_beta_prop-like | interpro domains | IPR013979 | 6 | 3 | 18293 | 2341 |
WDHD1,EIF2A,WDR5B |
| 3.101e-02 | -3.47 | FATC_dom | interpro domains | IPR003152 | 6 | 3 | 18293 | 2341 |
ATM,TRRAP,SMG1 |
| 3.101e-02 | -3.47 | Isoprenoid_synthase_dom | interpro domains | IPR008949 | 6 | 3 | 18293 | 2341 |
PDSS2,FDPS,FDFT1 |
| 3.105e-02 | -3.47 | KAT5 (K(lysine) acetyltransferase 5) | protein interactions | 10524 | 217 | 41 | 16036 | 2270 |
USP7,EP400,ACTG1,FANCD2,RCHY1,CEP126,PDCD5,PHC2,PRKCE,SRSF2,VPS72,MYC,ZEB1,PLEKHA4,MYB,TNK2,HMBOX1,PPARG,LDHA,ATXN1,BRCA1,ODC1,TRIM37,ANGPTL4,C1orf174,ARIH2,NAP1L5,DLEU1,UBTF,TRIB3,SRCAP,TRRAP,POLE2,HNRNPH3,KLF4,MBTD1,H2AFX,PTPN4,ATM,RBPJ,BMI1 |
| 3.106e-02 | -3.47 | low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | low_malignant_potential_(borderline)_tumour | 41 | 10 | 17775 | 2278 |
BRCA2,SRSF2,BRAF,NRAS,RNF43,BRCA1,ARID1A,MET,MAP2K4,FGFR1 |
| 3.112e-02 | -3.47 | VCL (vinculin) | protein interactions | 7414 | 92 | 20 | 16036 | 2270 |
PXN,TUBA1A,FN1,GINS3,TRIP6,ATP6V1A,SIRT7,HSPA5,FERMT2,RAP1GDS1,PTK2,PRKCA,ASNS,SSU72,UBR1,G6PD,SVIL,VAPB,VCL,CORO2B |
| 3.112e-02 | -3.47 | KIF5B (kinesin family member 5B) | protein interactions | 3799 | 92 | 20 | 16036 | 2270 |
DTNB,CUL7,TRIP6,KIF5A,SIRT7,KLC4,TRAK1,KIF5C,NUP43,SNAP25,KDM1A,RANBP2,ELP2,USPL1,SRP68,SNAP23,COPS5,DTNBP1,VPS52,RPS6KB2 |
| 3.113e-02 | -3.47 | salivary_gland-pharynx-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-pharynx-carcinoma-adenoid_cystic_carcinoma | 6 | 3 | 17775 | 2278 |
BRAF,NRAS,SPEN |
| 3.113e-02 | -3.47 | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_I | 6 | 3 | 17775 | 2278 |
BRAF,NRAS,KIAA1549 |
| 3.113e-02 | -3.47 | salivary_gland-maxillary_sinus-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-maxillary_sinus-carcinoma-adenoid_cystic_carcinoma | 6 | 3 | 17775 | 2278 |
BRAF,NRAS,SPEN |
| 3.113e-02 | -3.47 | maxillary_sinus | COSMIC cancer mutations | maxillary_sinus | 6 | 3 | 17775 | 2278 |
BRAF,NRAS,SPEN |
| 3.113e-02 | -3.47 | central_nervous_system-parietal_lobe-other-ganglioglioma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-other-ganglioglioma | 6 | 3 | 17775 | 2278 |
BRAF,KIAA1549,SMARCB1 |
| 3.113e-02 | -3.47 | sella_turcica | COSMIC cancer mutations | sella_turcica | 6 | 3 | 17775 | 2278 |
BRAF,KIAA1549,SMARCB1 |
| 3.113e-02 | -3.47 | central_nervous_system-cerebrum-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-cerebrum-glioma-astrocytoma_Grade_I | 6 | 3 | 17775 | 2278 |
BRAF,NRAS,KIAA1549 |
| 3.115e-02 | -3.47 | - | gene3d domains | 1.20.920.10 | 43 | 11 | 9988 | 1398 |
BAZ1A,ASH1L,BAZ2B,BRD4,TAF1,BAZ2A,SMARCA4,BRD9,KMT2A,BRWD3,TRIM66 |
| 3.120e-02 | -3.47 | MODULE_53 | MSigDB lists | MODULE_53 | 390 | 63 | 17758 | 2279 |
ADAM19,MCM6,AK2,TRPM2,RIBC2,SLC2A1,CSNK2A1,ZIC2,TTI1,CSTA,RAC3,DDIT4,IGF2BP3,ASNS,SLC7A11,ACD,COPS3,MYC,AP1M1,WIZ,SHMT2,CORO1A,MFAP2,CEP135,PEG10,CDK6,LRP3,TRIP13,HTRA2,SERBP1,MYB,PRPF19,DBN1,FADS1,GTF2H3,PRAME,EXOSC2,RFC4,RFC3,KCNQ3,PARP2,NPM3,GNG7,ZBED4,SULT4A1,ADSL,ARID1A,MCM2,SOX4,ISG15,CHAF1A,RPA1,ANXA1,PLIN2,HLA-DMA,HPRT1,SYNCRIP,INSIG1,PER1,FDPS,H2AFX,TNFRSF10D,MAGI1 |
| 3.124e-02 | -3.47 | purine nucleoside triphosphate metabolic process | biological process | GO:0009144 | 183 | 33 | 16441 | 2138 |
NDUFA5,AK2,ATP6V1A,NDUFB5,OLA1,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,AMPD3,NDUFV1,ENTPD5,ATP5G2,MYH3,NDUFA6,FXN,PFKFB4,BDNF,ITPA,LDHA,ATP6V0A1,NUDT15,HSPA1B,SNCA,STOML2,ATP5D,NME7,COQ9,SURF1,HK2,NDUFS5,ADK |
| 3.125e-02 | -3.47 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_21 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_21 | 6 | 3 | 17758 | 2279 |
HMGA2,CDK4,DDIT3 |
| 3.125e-02 | -3.47 | TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_DN | MSigDB lists | TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_DN | 6 | 3 | 17758 | 2279 |
EHBP1,TSPAN5,MBTPS2 |
| 3.125e-02 | -3.47 | CHESLER_BRAIN_QTL_TRANS | MSigDB lists | CHESLER_BRAIN_QTL_TRANS | 6 | 3 | 17758 | 2279 |
MYH9,PITPNB,TSPAN5 |
| 3.125e-02 | -3.47 | MCBRYAN_TERMINAL_END_BUD_DN | MSigDB lists | MCBRYAN_TERMINAL_END_BUD_DN | 6 | 3 | 17758 | 2279 |
CORO1A,NRIP1,PHGDH |
| 3.125e-02 | -3.47 | BAFNA_MUC4_TARGETS_UP | MSigDB lists | BAFNA_MUC4_TARGETS_UP | 6 | 3 | 17758 | 2279 |
ATF7IP,PTGS1,NEK6 |
| 3.125e-02 | -3.47 | TSAI_DNAJB4_TARGETS_DN | MSigDB lists | TSAI_DNAJB4_TARGETS_DN | 6 | 3 | 17758 | 2279 |
HMGA2,CD44,NOLC1 |
| 3.128e-02 | -3.46 | regulation of nuclear division | biological process | GO:0051783 | 157 | 29 | 16441 | 2138 |
PPP1R9B,CHMP2A,CUL7,MSX1,TEX14,CSNK2A1,SIRT2,PLCB1,MAD2L2,UBE2E1,PDE3A,TOM1L1,MSX2,ANAPC1,KLHL22,CDC16,NEK6,TOM1L2,NSMCE2,ANAPC11,ANAPC10,MAD1L1,ATM,BMP4,PRMT5,CAV2,DMRT1,ANAPC4,CHMP4C |
| 3.128e-02 | -3.46 | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | 192 | 34 | 17758 | 2279 |
FEZ2,SEC24D,ANKRD17,PAFAH1B1,B4GALT5,PDE4B,PPP2R2A,CUTC,BIRC2,NAMPT,PHC2,PTPN2,MBD2,TANK,LPIN2,TIMELESS,PPA1,TMPO,DDHD1,FAM172A,DDX24,UPP1,USP42,NFIA,TOP3A,TEX14,GNL1,UBR4,DCBLD2,GLS,RARS,IRAK2,PEX13,SLC43A1 |
| 3.128e-02 | -3.46 | GSE14308_TH17_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH17_VS_INDUCED_TREG_UP | 192 | 34 | 17758 | 2279 |
TCF12,DCTN3,MYCBP2,FEZ2,ATRX,OLA1,ZFP36L1,GYG1,INPP1,FOXO3,PAIP2,MAN1A1,SACS,MCAM,ENTPD5,ANAPC11,SSBP1,SIK3,KDM5B,FAM172A,STAG1,TSPYL4,KDM5A,ATOX1,RAP1B,MEX3B,FAM126B,PHF6,GADD45A,EHMT2,ADAM9,SLC4A7,NCOR1,MED20 |
| 3.128e-02 | -3.46 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 192 | 34 | 17758 | 2279 |
SLC12A7,SRM,PPDPF,SPRED2,EGR1,ARID2,ST6GAL1,HES6,CCNL2,BZW2,MFHAS1,DDIT4,AMPD3,INTS7,TTC3,TMEM14C,MYB,APEX1,TUBA1A,PDK1,ELOVL6,RAPGEF4,ARHGAP39,ZDHHC14,STK10,ISG15,PGD,GEMIN5,POLE2,GADD45A,DNAJC1,HIF1A,NSMCE1,ADK |
| 3.128e-02 | -3.46 | GSE17721_12H_VS_24H_POLYIC_BMDM_DN | MSigDB lists | GSE17721_12H_VS_24H_POLYIC_BMDM_DN | 192 | 34 | 17758 | 2279 |
TCF12,HMGA2,FOXO1,DDX18,FAM189B,FAM192A,MPHOSPH10,NOP16,TMEM161A,ANAPC11,PPCDC,PTGS1,KIAA0922,TMEM14C,SERBP1,PEA15,FAM98A,SLC40A1,RAB7A,TMEM126A,GPNMB,RHOT2,POLR2A,MLLT10,PWP1,TRAP1,DNAJA3,SYNGR2,RNF138,NCBP2,RIOK1,SENP3,KLHDC4,PTPN14 |
| 3.128e-02 | -3.46 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 192 | 34 | 17758 | 2279 |
VIPR1,EFNB2,ZNF292,MFGE8,KLC4,PDE4B,MAPK8IP3,GRINA,AP1B1,FOSL2,BMP6,SCAF8,HR,SLC7A11,METTL8,LYST,PEA15,FBXW4,TRIM13,RAPGEF4,RFX2,CUX1,SCMH1,CCNDBP1,IL6R,SOX4,RERE,SH3GL1,ARID3B,HIPK2,MBTD1,PSAP,GALNT10,BRWD3 |
| 3.128e-02 | -3.46 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | 192 | 34 | 17758 | 2279 |
TNIK,TCF3,ALG8,SBF2,CSNK1A1,RSRC1,CD96,PUS3,IDI1,ASAP1,UBR1,NUP133,ATIC,METTL8,PIGG,DDX31,KIAA0922,KDM5C,POLR1B,HMGCR,MYB,ANKRD33B,FOXN3,MAT2A,SLC23A2,EXO1,DDX3X,INSIG1,SQLE,CNOT6,NRP1,MID1,GPATCH4,PKIB |
| 3.128e-02 | -3.46 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | 192 | 34 | 17758 | 2279 |
SERINC5,SMAD7,ID2,SF3A3,RSL1D1,PRKCA,IQGAP2,PRKCH,MPHOSPH10,S100A10,FMNL1,FXN,POLR1E,RPS6KB2,KAT8,DDX28,PXN,GARS,SLC3A2,UPP1,ZNF512B,R3HDM1,MAP7D1,SUPT5H,SOX4,GADD45A,CHD3,PTPN4,FKBP5,RUNX1,MACROD1,TXN2,MUTYH,SPOCK2 |
| 3.128e-02 | -3.46 | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | 192 | 34 | 17758 | 2279 |
PCNT,ACTG1,PTPRA,RSL1D1,SF3A3,SLC25A44,PRKCA,HMOX2,FAM8A1,LPIN1,CIAPIN1,SACS,MPHOSPH10,UBE3A,FMNL1,CCDC88C,FXN,PRF1,POLR1E,HN1,TIMM8B,PXN,LGALS1,R3HDM1,MAP7D1,RANGAP1,DDX60,CPT1A,ANXA1,SVIL,PTPN4,FKBP5,RUNX1,TXN2 |
| 3.129e-02 | -3.46 | response to methylmercury | biological process | GO:0051597 | 10 | 4 | 16441 | 2138 |
HMBS,ALAD,CPOX,UROD |
| 3.129e-02 | -3.46 | cranial suture morphogenesis | biological process | GO:0060363 | 10 | 4 | 16441 | 2138 |
MSX2,INSIG2,BMP4,INSIG1 |
| 3.129e-02 | -3.46 | positive regulation of cardiac muscle cell differentiation | biological process | GO:2000727 | 10 | 4 | 16441 | 2138 |
EFNB2,RBPJ,BMP4,MEF2C |
| 3.129e-02 | -3.46 | negative regulation of necroptotic process | biological process | GO:0060546 | 10 | 4 | 16441 | 2138 |
RBCK1,CAV1,YBX3,BIRC2 |
| 3.129e-02 | -3.46 | membrane raft assembly | biological process | GO:0001765 | 10 | 4 | 16441 | 2138 |
ANXA2,CAV1,S100A10,CAV2 |
| 3.129e-02 | -3.46 | UMP biosynthetic process | biological process | GO:0006222 | 10 | 4 | 16441 | 2138 |
CAD,UMPS,CMPK1,UPP1 |
| 3.129e-02 | -3.46 | pyrimidine ribonucleoside monophosphate biosynthetic process | biological process | GO:0009174 | 10 | 4 | 16441 | 2138 |
CAD,UMPS,CMPK1,UPP1 |
| 3.129e-02 | -3.46 | pyrimidine ribonucleoside monophosphate metabolic process | biological process | GO:0009173 | 10 | 4 | 16441 | 2138 |
CAD,UMPS,CMPK1,UPP1 |
| 3.129e-02 | -3.46 | protoporphyrinogen IX metabolic process | biological process | GO:0046501 | 10 | 4 | 16441 | 2138 |
HMBS,ALAD,CPOX,UROD |
| 3.129e-02 | -3.46 | regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter | biological process | GO:0072364 | 10 | 4 | 16441 | 2138 |
NCOR2,SUPT20H,FOXO1,TCF7L2 |
| 3.129e-02 | -3.46 | snRNA transcription | biological process | GO:0009301 | 10 | 4 | 16441 | 2138 |
ELL,ICE2,ZC3H8,SNAPC4 |
| 3.129e-02 | -3.46 | fatty acid transmembrane transport | biological process | GO:1902001 | 10 | 4 | 16441 | 2138 |
SLC27A5,CPT1A,PRKAB2,SLC25A20 |
| 3.129e-02 | -3.46 | chondrocyte proliferation | biological process | GO:0035988 | 10 | 4 | 16441 | 2138 |
HMGA2,MMP16,DDR2,MMP14 |
| 3.129e-02 | -3.46 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' | biological process | GO:0034427 | 10 | 4 | 16441 | 2138 |
EXOSC2,EXOSC4,WDR61,DIS3L2 |
| 3.129e-02 | -3.46 | histone H4 deacetylation | biological process | GO:0070933 | 10 | 4 | 16441 | 2138 |
SIRT2,BAZ2A,SMARCAD1,SIRT7 |
| 3.129e-02 | -3.46 | UMP metabolic process | biological process | GO:0046049 | 10 | 4 | 16441 | 2138 |
CAD,UMPS,CMPK1,UPP1 |
| 3.132e-02 | -3.46 | epithelial tube formation | biological process | GO:0072175 | 125 | 24 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,LUZP1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SOX4,TCTN1,SKI,HIF1A,BMP4,APAF1,PRKACB,STK4,HS2ST1,MTHFD1 |
| 3.133e-02 | -3.46 | ORGANIC_ACID_TRANSPORT | MSigDB lists | ORGANIC_ACID_TRANSPORT | 41 | 10 | 17758 | 2279 |
SLC3A2,SERINC1,ARL6IP5,PRAF2,SLC25A12,SLC16A1,SLC1A1,SLC16A10,SLC25A1,SLC43A1 |
| 3.133e-02 | -3.46 | MODULE_455 | MSigDB lists | MODULE_455 | 41 | 10 | 17758 | 2279 |
RHOU,UNC13A,NKD2,ABCC2,DYNC2H1,NHSL1,CSTA,FOXRED1,PKIB,MEF2C |
| 3.133e-02 | -3.46 | NAKAMURA_METASTASIS_MODEL_UP | MSigDB lists | NAKAMURA_METASTASIS_MODEL_UP | 41 | 10 | 17758 | 2279 |
MALL,COL17A1,DDX24,ACD,PDE10A,HIRIP3,AKAP13,TUBB6,CMTM3,HTRA2 |
| 3.136e-02 | -3.46 | negative regulation of cellular protein metabolic process | biological process | GO:0032269 | 957 | 144 | 16441 | 2138 |
UBN1,NF1,CSNK2A1,BCOR,CHAC1,SIRT2,PRKCA,NLE1,BIRC2,UBR5,SKI,SMARCB1,ANAPC1,ECM1,ZFYVE28,ANAPC11,ANAPC10,MAD1L1,HRG,ATF4,TFPI,GMFB,CAV1,BRCA1,SOX4,DDX3X,EIF4ENIF1,DNAJC1,SH3RF1,PER1,SOCS4,TNFRSF10D,SPOCK3,TNRC6A,FOXO1,PAX2,UBXN1,OPHN1,SMAD7,PID1,PDCD5,IGF2BP3,DDIT4,FKBP1A,ELL,P3H1,CNST,MYC,IGF2BP1,HMGCR,ADARB1,ZNF675,PSMA1,HERPUD1,ISG15,UBE2E1,EPRS,SYNCRIP,PMEPA1,DPEP1,NCOR1,SMYD3,PRKAR2A,TESC,AGO3,SPRED2,ASH1L,MAP2K5,BIRC6,PAFAH1B1,RIPK1,CSTA,PIBF1,HSPA1A,KDM1A,PAIP2,MPHOSPH10,SOCS1,DNAJB6,UCHL5,WAC,IKBKB,SOCS6,FHIT,SERPINH1,PRMT3,KIRREL2,ENC1,SNCA,SMAD3,CDC16,SMARCC1,G6PD,DNAJA3,KLF4,DUSP19,ATG7,ANXA2,EIF2B3,PARD3,PKIB,NIFK,SUPT6H,AGO2,IGF2BP2,AKT1S1,PPP1R1C,GAS6,NOL3,TGFB2,PSMF1,GIGYF2,MAD2L2,SFI1,PTPN2,ABL1,TRIAP1,CELF1,FBXO31,ERRFI1,CD44,SAMD4A,ZFYVE1,CRIM1,KDM5A,TEX14,NXN,MEN1,UBC,HSPA1B,DKK1,TRIB3,KLHL22,IREB2,GADD45A,SET,GLG1,EIF2S1,ATM,RBM26,BMP4,NR2F2,IGBP1,ANAPC4 |
| 3.137e-02 | -3.46 | V$AR_01 | MSigDB lists | V$AR_01 | 146 | 27 | 17758 | 2279 |
DTNB,TRERF1,ZNF654,ID2,LRRC8A,PRDM1,R3HDM2,SNAP25,IP6K2,KCNH2,SYMPK,FAM49A,SLC9A5,RAB10,NCDN,STOML2,DAGLA,ADNP,TP53BP1,PER1,LUC7L3,VGF,NCKIPSD,SDCBP2,ZNF532,TNRC6A,SLC43A1 |
| 3.141e-02 | -3.46 | inclusion body | cellular component | GO:0016234 | 71 | 15 | 17570 | 2233 |
RANBP2,ATF4,RAD18,WDFY3,URB2,ATXN1,CLU,AGL,TRIM37,HSPA1A,HERPUD1,TRIM66,MAPT,SNCA,HSPA1B |
| 3.142e-02 | -3.46 | RNase_T | pfam domains | PF00929 | 10 | 4 | 16629 | 2165 |
AEN,ISG20L2,ERI3,ERI1 |
| 3.143e-02 | -3.46 | TTCYNRGAA_V$STAT5B_01 | MSigDB lists | TTCYNRGAA_V$STAT5B_01 | 314 | 52 | 17758 | 2279 |
DLL4,FN1,RBFOX2,PPARGC1B,STXBP6,SBF2,ADAMTS6,TRIM15,BIRC2,MAP2K3,SLC30A7,ELL,PI4KB,SLC38A5,NEK6,UBR1,SEC24C,VGF,MED24,ADCK4,OGG1,HTRA2,AUP1,IPO11,TMLHE,PPP1R9B,BDNF,MPP6,ADAMTSL3,IFT43,POLK,TEAD1,C1QTNF1,HOMER2,SETD2,COL4A3BP,PRDM1,LAMA2,KRTCAP2,PALLD,SYMPK,SLC50A1,HSD3B7,PDLIM1,NME7,HNRNPR,KLF4,CTAGE5,CLU,NRP1,AP2S1,ATXN7L2 |
| 3.143e-02 | -3.46 | gene silencing by miRNA | biological process | GO:0035195 | 35 | 9 | 16441 | 2138 |
SMAD3,LIN28B,DROSHA,XPO5,AGO2,CNOT6,RAN,AGO3,TNRC6A |
| 3.143e-02 | -3.46 | pteridine-containing compound metabolic process | biological process | GO:0042558 | 35 | 9 | 16441 | 2138 |
MTHFD2,GART,ALDH1L2,ATIC,SHMT2,MTHFD1L,MTHFD2L,MTR,MTHFD1 |
| 3.143e-02 | -3.46 | transport of virus | biological process | GO:0046794 | 35 | 9 | 16441 | 2138 |
THOC5,VPS37A,KPNA1,KPNA3,VPS37B,CAV1,RAN,CAV2,UBC |
| 3.144e-02 | -3.46 | V$AP4_Q6_01 | MSigDB lists | V$AP4_Q6_01 | 239 | 41 | 17758 | 2279 |
GNB3,CLDN15,DLL4,MAP3K13,MYO7A,TMEM109,HES6,BARX2,ATF7IP,RSRC1,GIGYF2,GABPB2,WNT2B,TMEM184A,SPG21,MCAM,KDM2A,MYC,MYH3,METTL8,ETV1,PNMA1,HN1,MOSPD1,ZNF646,FAM98A,BRD4,KIRREL2,PPAT,LGALS1,MEF2D,MBNL2,HSD3B7,SPOP,YTHDF2,EIF4ENIF1,HOXA3,SVIL,CSMD3,ZMAT3,SPOCK2 |
| 3.144e-02 | -3.46 | MORF_MT4 | MSigDB lists | MORF_MT4 | 239 | 41 | 17758 | 2279 |
ZNF292,NF1,ATRX,PRKCSH,FAM189B,SLC2A1,KLHL18,JMJD6,TTI1,PSMF1,POLR3D,RAP1A,JAG1,TBC1D22A,CACNB2,NCKIPSD,ZNF710,OGG1,RPS6KB2,ZBTB17,CHD9,SIK3,MSX1,LSM12,SFSWAP,FOXN3,KIAA0586,PIK3CB,RERE,HTR7,SEC31A,RANBP2,SLC30A3,RBBP8,CHD3,CRCP,SLC25A11,ZNF32,RUNX1,NFRKB,ARC |
| 3.145e-02 | -3.46 | microtubule-based process | biological process | GO:0007017 | 517 | 82 | 16441 | 2138 |
CGN,CUL7,PCNT,PAFAH1B1,KIF5A,ACTR3,TUBE1,MYH9,TUBB6,PIBF1,BIRC2,BLOC1S2,DST,NEK6,XRCC2,DTNBP1,CCDC40,CEP63,RAN,CEP135,LYST,SEH1L,PHLDB2,CFAP221,TUBA1A,KATNAL1,ASUN,KIF15,ARHGEF10,CAMSAP2,CAV1,BRCA1,SON,PEX1,KIF16B,ARMC4,IFT81,ARHGAP21,BRCA2,CHD3,E2F4,IFT140,DNAH2,MID1,MAPT,PARD3,DCTN3,KIZ,IFT57,KIF5C,MAP1S,MLH1,CEP126,OPA1,DNAH1,SPIRE1,NAV1,DYNC2H1,TTLL5,IFT43,HAUS6,TEX14,MAP7D1,PTK2,RHOT2,BLOC1S4,DNAH14,DYNC1H1,ATXN7,BICD1,NME7,GADD45A,WDR35,HIF1A,SDCCAG8,DNAH17,BCAS3,SLC16A1,PEX13,NCOR1,KIAA0196,KIF1B |
| 3.145e-02 | -3.46 | human chr22q12.1 | chromosome location | human chr22q12.1 | 25 | 6 | 26250 | 2590 |
PES1,PITPNB,TTC28,SRRD,TFIP11,TTC28-AS1 |
| 3.155e-02 | -3.46 | NUCLEAR_PORE | MSigDB lists | NUCLEAR_PORE | 30 | 8 | 17758 | 2279 |
RANBP2,KPNA1,KPNA3,NUP133,RANGAP1,XPO7,NUP160,NUP214 |
| 3.155e-02 | -3.46 | BIOCARTA_NO1_PATHWAY | MSigDB lists | BIOCARTA_NO1_PATHWAY | 30 | 8 | 17758 | 2279 |
SLC7A1,RYR2,CAV1,PDE2A,PDE3B,PRKAR2A,PDE3A,PRKACB |
| 3.155e-02 | -3.46 | MODULE_524 | MSigDB lists | MODULE_524 | 30 | 8 | 17758 | 2279 |
FLNC,TPM4,SVIL,MYH9,ENC1,VCL,FLNB,SPTAN1 |
| 3.155e-02 | -3.46 | REACTOME_DNA_STRAND_ELONGATION | MSigDB lists | REACTOME_DNA_STRAND_ELONGATION | 30 | 8 | 17758 | 2279 |
RFC4,MCM6,RFC3,PRIM2,POLA1,MCM5,MCM2,RPA1 |
| 3.155e-02 | -3.46 | SKELETAL_MUSCLE_DEVELOPMENT | MSigDB lists | SKELETAL_MUSCLE_DEVELOPMENT | 30 | 8 | 17758 | 2279 |
TTN,IFRD1,CACNB2,TBX3,CACNA1H,SVIL,BMP4,MBNL1 |
| 3.155e-02 | -3.46 | GCM_MAX | MSigDB lists | GCM_MAX | 30 | 8 | 17758 | 2279 |
MYCBP2,HNRNPR,USPL1,LSM14A,LEMD3,BANF1,RNF138,SMG1 |
| 3.159e-02 | -3.45 | CHROMOSOMAL_PART | MSigDB lists | CHROMOSOMAL_PART | 95 | 19 | 17758 | 2279 |
RFC4,RFC3,ATRX,PAFAH1B1,POLA1,SUMO3,APTX,MCM2,FOXC1,RPA1,ACD,SUV39H2,ZNF330,PAM,TIMELESS,PURB,RAN,TMPO,TERF2 |
| 3.161e-02 | -3.45 | DEAD_ATP_HELICASE | prosite domains | PS00039 | 25 | 7 | 11866 | 1504 |
DDX3X,DDX31,DDX24,DDX10,DDX18,DDX49,EIF4A2 |
| 3.165e-02 | -3.45 | Laminin_G_2 | pfam domains | PF02210 | 35 | 9 | 16629 | 2165 |
LAMA4,CELSR1,CELSR3,CNTNAP3,FAT1,GAS6,LAMA2,CNTNAP3B,LAMA5 |
| 3.178e-02 | -3.45 | acral_lentiginous | COSMIC cancer mutations | acral_lentiginous | 768 | 116 | 17775 | 2278 |
RTTN,SPRED2,TRPM2,DPH1,PCNT,DDX18,UBN1,NF1,KIF5A,OSBPL9,ST3GAL6,STK33,CUTC,FLNB,ARMC6,PHKA1,RABGAP1L,MYH3,HYAL1,ZFP37,MYH15,ANO8,BCAP29,MET,TMLHE,PHLDB2,NRAS,ABCC4,SSFA2,KIRREL2,SLC38A1,WDHD1,AKAP13,BRCA1,KMT2C,CA5B,ATP8B2,EDEM2,ZNF91,FGFR1,TPK1,KIF16B,WARS,OSBPL1A,TIMM44,RAD54B,VDR,MSX2,BRCA2,IQCH,TRRAP,ASTN2,CCNT1,INTS9,ACP1,CSMD3,DPP4,ABCC3,NFASC,TNFRSF10D,ZNF532,CATSPERG,PARD3,EP400,WDR75,BRAF,CELSR1,SH2D3A,SUPT6H,PAX2,PDE4B,GTF2IRD1,SMG7,RCAN1,OPA1,ARID1B,ANXA10,ABL1,ZNF239,SACS,STC2,PRICKLE2,TTC17,AMOT,ZCCHC7,PABPC1,NAV3,SCAF11,FBXO17,RREB1,LRRIQ1,TYW1,DHX34,FERMT2,BMS1,IMPDH2,ARID1A,ARHGAP32,MEN1,PLCB1,CPT1A,ZNF708,APBB3,VPS13C,LRP1B,ATAD5,FAM135A,HIF1A,ZZEF1,ZCCHC6,ITGB4,BRWD3,TBCK,SMYD3,ARHGAP27,IPO4 |
| 3.184e-02 | -3.45 | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 179 | 32 | 17758 | 2279 |
SPRED2,FEZ2,RTN4,CMTM3,SLC39A11,CHN1,AMPD3,ELL,MCAM,SURF2,S100A10,LDOC1L,PVRL3,RABGAP1L,GLTP,NDUFA6,SAMD3,TBC1D8,ANTXR2,TMEM216,LGALS1,RABAC1,PRDM1,ODC1,NEU1,MGAT2,TP53BP1,PMEPA1,PAM,PPP3CC,ANXA2,ZSWIM6 |
| 3.184e-02 | -3.45 | GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN | 179 | 32 | 17758 | 2279 |
SPRED2,KLHL18,RTN4,CMTM3,PHLDA2,ANKRD13A,TAF3,LDOC1L,PVRL3,RABGAP1L,AGL,MPST,PEA15,POLK,SETD2,RAP1GDS1,SETD7,ODC1,SRA1,MGAT2,TAF2,EPN2,TRRAP,SPAG9,ITPRIPL1,POLR3E,XPNPEP1,RBPJ,ANXA2,HEATR1,DHCR7,ZSWIM6 |
| 3.194e-02 | -3.44 | skin-ear-malignant_melanoma | COSMIC cancer mutations | skin-ear-malignant_melanoma | 127 | 24 | 17775 | 2278 |
GDAP1,BRAF,NRAS,BIRC6,UPK3B,NF1,MAP3K13,ARID1A,KCNH3,STK33,CPT1A,EHBP1,FOXO3,PIK3CB,TMEM132B,LRP1B,BRCA2,TRRAP,VCAN,TSSC1,SMG1,LYST,PTPRK,MEF2C |
| 3.196e-02 | -3.44 | negative regulation of organelle organization | biological process | GO:0010639 | 290 | 49 | 16441 | 2138 |
CHMP2A,FEZ2,SUPT6H,C16orf45,CSNK2A1,PID1,BCOR,NOL3,OPA1,UBR5,HSPA1A,MAD2L2,KDM1A,SBDS,SKI,TOM1L1,SMARCB1,TERF2IP,ANAPC1,ACD,ANAPC11,TRIAP1,ANAPC10,MAD1L1,RDX,CORO1A,FXN,DMRT1,TERF2,SPTAN1,PHLDB2,LIMA1,KDM5A,GMFB,TEX14,BRCA1,TRIM37,UBE2E1,SNCA,KLHL22,CDC16,TOM1L2,INSIG1,SET,ATG7,ATM,BMP4,MID1,ANAPC4 |
| 3.200e-02 | -3.44 | HALLMARK_E2F_TARGETS | MSigDB lists | HALLMARK_E2F_TARGETS | 199 | 35 | 17758 | 2279 |
MCM6,AK2,MLH1,NOP56,DCTPP1,SRSF2,PHF5A,MCM5,MYC,PDS5B,TIMELESS,RAN,PRPS1,TRIP13,TMPO,HN1,NAA38,RFC3,PRIM2,GINS3,STAG1,CDK4,PSMC3IP,TBRG4,BRCA1,PNN,MCM2,RPA1,BRCA2,MTHFD2,SYNCRIP,LUC7L3,H2AFX,EIF2S1,NOLC1 |
| 3.201e-02 | -3.44 | regulation of cytokine-mediated signaling pathway | biological process | GO:0001959 | 138 | 26 | 16441 | 2138 |
ZNF675,RBCK1,CYLD,IFNGR2,PAFAH1B1,PPARG,RIPK1,GAS6,CAV1,NOL3,UBE2K,BIRC2,HSPA1A,UBC,HSPA1B,PTPN2,ECM1,PXDN,SOCS1,HIF1A,LSM14A,DNAJA3,IRAK2,IKBKB,TNFRSF1A,CDC37 |
| 3.202e-02 | -3.44 | CBX3 (chromobox homolog 3) | protein interactions | 11335 | 98 | 21 | 16036 | 2270 |
CUL7,FN1,SMARCAD1,SIRT7,BRCA1,TNKS1BP1,POGZ,MAD2L2,MGA,RING1,POLR2A,CHAF1A,EHMT2,ADNP,TP53BP1,BANF1,TAF4,RELB,RNF2,KDM5C,ATXN7L2 |
| 3.202e-02 | -3.44 | SMC1A (structural maintenance of chromosomes 1A) | protein interactions | 8243 | 98 | 21 | 16036 | 2270 |
CAMKK2,MCM6,CUL7,STAG1,SIRT6,ATRX,POLA1,SMARCAD1,CDK4,HDAC8,BRCA1,MLH1,POLR2A,RPA1,EHMT2,SSU72,NSMCE2,PDS5B,ATM,RNF2,MET |
| 3.220e-02 | -3.44 | PAPOLA (poly(A) polymerase alpha) | protein interactions | 10914 | 48 | 12 | 16036 | 2270 |
SARS,NARS,RRAGA,SIRT2,MTHFD1L,WDR33,SUPT5H,CPSF3,PABPC1,TARS,NUDC,MTHFD1 |
| 3.220e-02 | -3.44 | SENP3 (SUMO1/sentrin/SMT3 specific peptidase 3) | protein interactions | 26168 | 48 | 12 | 16036 | 2270 |
KMT2D,HIF1A,CDK4,WDR18,ATF7IP,RNF2,MEF2D,MEN1,KMT2A,CDK6,PELP1,USP15 |
| 3.220e-02 | -3.44 | RPE (ribulose-5-phosphate-3-epimerase) | protein interactions | 6120 | 48 | 12 | 16036 | 2270 |
XYLB,DNM3,TRAP1,TLE3,G6PD,UPP1,MRI1,TRIO,NSUN6,ADSL,CLU,PRKACB |
| 3.220e-02 | -3.44 | CTNNBL1 (catenin, beta like 1) | protein interactions | 56259 | 48 | 12 | 16036 | 2270 |
SNW1,KPNA1,CTNNBL1,BCAS2,NSRP1,PRPF31,STAMBP,PLRG1,BUD31,PRMT5,PRPF19,SRPK2 |
| 3.220e-02 | -3.44 | AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase) | protein interactions | 178 | 48 | 12 | 16036 | 2270 |
CAT,FKBP1A,GARS,TOM1L2,COPS5,PRKAB2,CUL2,TKFC,ASB3,PUS1,RAN,YTHDF2 |
| 3.220e-02 | -3.44 | TCOF1 (Treacher Collins-Franceschetti syndrome 1) | protein interactions | 6949 | 48 | 12 | 16036 | 2270 |
UBTF,NDUFV1,CUL7,SIRT6,SIRT7,GPN1,S100A16,TERF2,RPA1,SRPK2,NOP56,TOP1 |
| 3.225e-02 | -3.43 | 3',5'-cyclic-AMP phosphodiesterase activity | molecular function | GO:0004115 | 10 | 4 | 16491 | 2164 |
PDE4A,PDE3A,PDE8B,PDE4B |
| 3.232e-02 | -3.43 | TTGGGAG,MIR-150 | MSigDB lists | TTGGGAG,MIR-150 | 89 | 18 | 17758 | 2279 |
YDJC,PAFAH1B1,ZMYM5,ATAT1,IKBIP,FOXP1,ERC1,POM121,SRSF2,IRAK2,MMP14,ETF1,MBD6,NR2F2,MAP3K12,SEH1L,MYB,TMCC1 |
| 3.232e-02 | -3.43 | CHEN_LIVER_METABOLISM_QTL_CIS | MSigDB lists | CHEN_LIVER_METABOLISM_QTL_CIS | 89 | 18 | 17758 | 2279 |
PIGM,PIGN,INSIG2,C2orf76,ACTR3,TMEM183A,TATDN3,DDR2,HES6,ZRANB3,NAV1,NME7,UCHL5,RABGAP1L,BPNT1,RPS6KC1,CEP170,NIT1 |
| 3.233e-02 | -3.43 | TPR_1 | pfam domains | PF00515 | 52 | 12 | 16629 | 2165 |
TTC1,TTC27,PPID,IFIT5,CTR9,TTC3,FKBP5,GTF3C3,TTC17,TTC28,TOMM34,TRAPPC12 |
| 3.234e-02 | -3.43 | HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B) | protein interactions | 3182 | 81 | 18 | 16036 | 2270 |
CUL7,CUL4A,PTBP2,FN1,DROSHA,RBFOX2,HSD17B10,HNRNPA3,RPA1,POLR3D,AHNAK,SNAP23,COPS5,CUL2,H2AFX,SHMT2,RNF2,COPS6 |
| 3.238e-02 | -3.43 | histone H3-K4 demethylation | biological process | GO:0034720 | 6 | 3 | 16441 | 2138 |
KDM5C,KDM5B,KDM1A |
| 3.238e-02 | -3.43 | RNA replication | biological process | GO:0039703 | 6 | 3 | 16441 | 2138 |
SUPT5H,ATG7,SMARCB1 |
| 3.238e-02 | -3.43 | regulation of MDA-5 signaling pathway | biological process | GO:0039533 | 6 | 3 | 16441 | 2138 |
TKFC,DDX60,ANKRD17 |
| 3.238e-02 | -3.43 | pyrimidine nucleobase biosynthetic process | biological process | GO:0019856 | 6 | 3 | 16441 | 2138 |
CAD,UMPS,CMPK1 |
| 3.238e-02 | -3.43 | purine nucleoside monophosphate catabolic process | biological process | GO:0009128 | 6 | 3 | 16441 | 2138 |
HPRT1,AMPD3,NT5E |
| 3.238e-02 | -3.43 | hepatocyte growth factor receptor signaling pathway | biological process | GO:0048012 | 6 | 3 | 16441 | 2138 |
SIRT2,NRP1,MET |
| 3.238e-02 | -3.43 | positive regulation of vesicle fusion | biological process | GO:0031340 | 6 | 3 | 16441 | 2138 |
ANXA2,C2CD5,ANXA1 |
| 3.238e-02 | -3.43 | mitochondrial respiratory chain complex III biogenesis | biological process | GO:0097033 | 6 | 3 | 16441 | 2138 |
UQCC2,UQCC1,BCS1L |
| 3.238e-02 | -3.43 | S-adenosylmethionine cycle | biological process | GO:0033353 | 6 | 3 | 16441 | 2138 |
AHCYL1,MRI1,AHCYL2 |
| 3.238e-02 | -3.43 | cGMP catabolic process | biological process | GO:0046069 | 6 | 3 | 16441 | 2138 |
PDE2A,PDE10A,PDE9A |
| 3.238e-02 | -3.43 | protection from non-homologous end joining at telomere | biological process | GO:0031848 | 6 | 3 | 16441 | 2138 |
TERF2IP,ACD,TERF2 |
| 3.238e-02 | -3.43 | histone H3-K27 methylation | biological process | GO:0070734 | 6 | 3 | 16441 | 2138 |
EHMT2,CHD5,EHMT1 |
| 3.238e-02 | -3.43 | 'de novo' pyrimidine nucleobase biosynthetic process | biological process | GO:0006207 | 6 | 3 | 16441 | 2138 |
CAD,UMPS,CMPK1 |
| 3.238e-02 | -3.43 | meiotic cytokinesis | biological process | GO:0033206 | 6 | 3 | 16441 | 2138 |
KIAA0196,ACTR3,SPIRE1 |
| 3.238e-02 | -3.43 | respiratory chain complex III assembly | biological process | GO:0017062 | 6 | 3 | 16441 | 2138 |
UQCC2,UQCC1,BCS1L |
| 3.238e-02 | -3.43 | tetrahydrofolate biosynthetic process | biological process | GO:0046654 | 6 | 3 | 16441 | 2138 |
GART,ATIC,MTHFD1 |
| 3.238e-02 | -3.43 | regulation of heart rate by chemical signal | biological process | GO:0003062 | 6 | 3 | 16441 | 2138 |
TPM1,KCNH2,NOS1AP |
| 3.238e-02 | -3.43 | osteoclast development | biological process | GO:0036035 | 6 | 3 | 16441 | 2138 |
ANXA2,FOXP1,PAFAH1B1 |
| 3.238e-02 | -3.43 | mitochondrial respiratory chain complex III assembly | biological process | GO:0034551 | 6 | 3 | 16441 | 2138 |
UQCC2,UQCC1,BCS1L |
| 3.238e-02 | -3.43 | viral RNA genome replication | biological process | GO:0039694 | 6 | 3 | 16441 | 2138 |
SUPT5H,ATG7,SMARCB1 |
| 3.239e-02 | -3.43 | PSME3 (proteasome activator subunit 3) | protein interactions | 10197 | 145 | 29 | 16036 | 2270 |
PRKAB2,HSPA5,PSMA1,WDR25,SF3A3,MYH9,SNAPC4,MGA,UBC,FAM192A,TSR1,CMSS1,AHNAK,SRSF2,SERF2,CAMTA2,RAD18,ZKSCAN1,KANSL1,MBTD1,DTNBP1,HIBCH,AHCYL1,TBXA2R,TXN2,FBXL19,YEATS2,PARD3,CLK2 |
| 3.240e-02 | -3.43 | GAL_LEUKEMIC_STEM_CELL_UP | MSigDB lists | GAL_LEUKEMIC_STEM_CELL_UP | 127 | 24 | 17758 | 2279 |
TNIK,NF1,WDFY3,MYO10,ZMYM5,ZBED4,ZFP36L1,RCAN1,EVPL,RNASEH2B,TMEM187,UBR4,SLC9A5,PPP1R9A,ARIH2,PEX1,MTUS1,DST,GPATCH1,MED20,ITGB4,PDLIM5,TSPAN5,LPP |
| 3.246e-02 | -3.43 | DIS3L (DIS3 like exosome 3'-5' exoribonuclease) | protein interactions | 115752 | 18 | 6 | 16036 | 2270 |
EXOSC2,EXOSC4,SKIV2L2,ZNF598,HSPA1A,GIGYF2 |
| 3.246e-02 | -3.43 | TRIM15 (tripartite motif containing 15) | protein interactions | 89870 | 18 | 6 | 16036 | 2270 |
TRIM15,SNW1,PXN,ACD,EHMT1,TAF9B |
| 3.246e-02 | -3.43 | NOL10 (nucleolar protein 10) | protein interactions | 79954 | 18 | 6 | 16036 | 2270 |
WDR36,MPHOSPH10,RBM19,DDX18,SIRT7,NOL6 |
| 3.246e-02 | -3.43 | ALS2CR11 (amyotrophic lateral sclerosis 2 chromosome region candidate 11) | protein interactions | 151254 | 18 | 6 | 16036 | 2270 |
VIM,MCM6,BRCA1,TFIP11,DNAJA3,CCDC85B |
| 3.246e-02 | -3.43 | ZNF830 (zinc finger protein 830) | protein interactions | 91603 | 18 | 6 | 16036 | 2270 |
SF3A3,SNW1,THOC5,PPIL2,SF3A1,FRA10AC1 |
| 3.246e-02 | -3.43 | ROBO2 (roundabout guidance receptor 2) | protein interactions | 6092 | 18 | 6 | 16036 | 2270 |
MYCBP2,TRIM13,OLFM2,RPS6KA5,MYC,RDH11 |
| 3.246e-02 | -3.43 | CCDC106 (coiled-coil domain containing 106) | protein interactions | 29903 | 18 | 6 | 16036 | 2270 |
TERF2IP,ATF4,COPS6,UTP14A,CAMK1,TERF2 |
| 3.246e-02 | -3.43 | CRBN (cereblon) | protein interactions | 51185 | 18 | 6 | 16036 | 2270 |
CUL4A,COPS6,COPS4,COPS5,COPS3,KDM1A |
| 3.248e-02 | -3.43 | Xpo1 | pfam domains | PF08389 | 6 | 3 | 16629 | 2165 |
TNPO3,XPO6,XPO5 |
| 3.248e-02 | -3.43 | DUSP | pfam domains | PF06337 | 6 | 3 | 16629 | 2165 |
USP20,USP11,USP15 |
| 3.248e-02 | -3.43 | eIF2A | pfam domains | PF08662 | 6 | 3 | 16629 | 2165 |
WDHD1,EIF2A,WDR5B |
| 3.248e-02 | -3.43 | Sec23_helical | pfam domains | PF04815 | 6 | 3 | 16629 | 2165 |
SEC24A,SEC24D,SEC24C |
| 3.248e-02 | -3.43 | Plectin | pfam domains | PF00681 | 6 | 3 | 16629 | 2165 |
DST,EVPL,DSP |
| 3.248e-02 | -3.43 | Sec23_trunk | pfam domains | PF04811 | 6 | 3 | 16629 | 2165 |
SEC24A,SEC24D,SEC24C |
| 3.248e-02 | -3.43 | Sec23_BS | pfam domains | PF08033 | 6 | 3 | 16629 | 2165 |
SEC24A,SEC24D,SEC24C |
| 3.248e-02 | -3.43 | tRNA_SAD | pfam domains | PF07973 | 6 | 3 | 16629 | 2165 |
AARS,TARS,AARS2 |
| 3.248e-02 | -3.43 | MCM_N | pfam domains | PF14551 | 6 | 3 | 16629 | 2165 |
MCM6,MCM2,MCM5 |
| 3.248e-02 | -3.43 | zf-Sec23_Sec24 | pfam domains | PF04810 | 6 | 3 | 16629 | 2165 |
SEC24A,SEC24D,SEC24C |
| 3.249e-02 | -3.43 | apoptotic process | biological process | GO:0006915 | 1059 | 158 | 16441 | 2138 |
POLB,CUL4A,NF1,TNFRSF21,TMEM109,CSNK2A1,CHAC1,PRKCA,NLE1,BIRC2,CIAPIN1,MRPS30,NEK6,PMAIP1,ATG3,FNIP2,YARS,AVEN,TIMM50,ATF4,PPARG,C5AR1,MCL1,SHISA5,CAV1,BRCA1,SAP30BP,DDX3X,ZNF622,BRCA2,SH3RF1,ARL6IP5,TNFRSF1A,FIS1,PPP3CC,CLU,ZC3H8,TNFRSF10D,ZMAT3,MTCH1,MEF2C,IFT57,FOXO1,SLK,PAX2,TRIO,DPF2,CDIP1,ZFP36L1,PDCD7,TGFBR2,PDCD5,RHBDD1,DDIT4,PRKCE,MYC,ANP32B,PRF1,PEA15,KRT20,CRADD,STPG1,PSMA1,RYR2,OBSCN,LIG4,SRA1,HERPUD1,MYBBP1A,KPNA1,HK2,RRAGA,PTRH2,DPEP1,BRSK2,ARHGAP10,MAP2K4,SART1,MAP2K5,BIRC6,RIPK1,SEMA6A,BLOC1S2,BRE,PPID,DNAJB6,SHF,BCAP29,RMDN3,FHIT,PEG10,KMT2A,CASP10,PERP,HTRA2,CASP8AP2,PRAME,PDK1,DDX41,PARP2,LGALS1,VIM,MEF2D,AKAP13,DSP,SNCA,SMAD3,ZC3H12A,HIPK2,DNAJA3,KLF4,TRAF3,RPS6KB1,RNF130,BAG1,MAPT,MAP1S,RTN4,MLH1,GAS6,ZNF346,OPA1,TGFB2,NOL3,FOXO3,PHLDA2,PSMF1,MFSD10,ABL1,SNW1,CTNNBL1,DSG2,TRIAP1,NISCH,S100A14,CD44,SPTAN1,ARHGEF12,PTK2,IL6R,CAAP1,UBE2K,RHOT2,UBC,MFN2,TRIB3,GADD45A,CUL2,CSRNP1,TMEM219,AEN,ATM,APAF1,IGBP1,RABEP1,KIF1B,DDIT3,STK4 |
| 3.249e-02 | -3.43 | PKM (pyruvate kinase, muscle) | protein interactions | 5315 | 151 | 30 | 16036 | 2270 |
SLC3A2,CUL7,OLFM2,FN1,PRDX6,CDK4,RAP1B,LDHA,IKBKAP,RAB10,ISG15,POLE2,ANXA7,PPID,HIF1A,TRAP1,UCHL5,HERC1,COPS5,DNAJA3,BANF1,CUL2,H2AFX,ME1,FUS,AGL,PDLIM5,SRP14,IPO11,LYPLA2 |
| 3.253e-02 | -3.43 | TK1 (thymidine kinase 1, soluble) | protein interactions | 7083 | 163 | 32 | 16036 | 2270 |
FN1,ATP6V1A,KIF5A,CENPB,FLAD1,WIZ,WDR60,UPF2,CPSF3L,PTPRK,KDM6B,DEAF1,TUBA1A,KLHL23,CDK4,JMJD1C,EIF4A2,WDR18,GPCPD1,METTL23,SUMO3,ODC1,AGAP1,TMSB4X,RPA1,DDAH2,TTC38,HSPBAP1,WDR73,TRMT2A,PTPN4,COPS6 |
| 3.258e-02 | -3.42 | BIOSYNTHETIC_PROCESS | MSigDB lists | BIOSYNTHETIC_PROCESS | 461 | 73 | 17758 | 2279 |
MVK,EIF3C,DPH1,MRPL10,CERS5,GPR143,PIGH,PLOD1,COX10,AARS,PABPC4,PAIP2,IDI1,ETF1,ME1,CMPK1,YARS,CSGALNACT2,ATF4,GCNT2,KRT7,MTIF2,EIF3J,CPOX,BRCA1,SERP1,EIF3H,HSD3B7,WARS,PYCR1,DDAH2,HPRT1,ALAD,COPS5,PEMT,LARGE,ATG7,EIF2B3,CHST11,ALG8,TRAK1,FARS2,DPM3,IGF2BP2,TGFB2,BMP6,PEX7,PI4KB,PIGG,PTGS1,GMDS,PNPLA3,ALDH18A1,COQ3,LPCAT1,SAMD4A,RPS6KB2,FADS1,ALG6,TSTA3,PPAT,EIF4A2,EIF2A,ABCF1,RARS,ALG5,RPL28,FDPS,FNTB,UMPS,ADK,DHCR7,PDSS2 |
| 3.267e-02 | -3.42 | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP | MSigDB lists | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP | 186 | 33 | 17758 | 2279 |
FBXO45,SNX27,CHST11,CELSR3,ATF7IP,GRINA,GIGYF2,KCTD11,SIPA1L3,JAZF1,AP1M1,CORO1A,PCOLCE2,NAA35,CSGALNACT2,VPS13B,DDX41,ZNF414,GLTSCR2,BMS1,SATB2,EVI5,POLG2,CCDC28B,SH3GL1,IREB2,G6PD,INTS5,CCDC146,SDCCAG8,TBPL1,RIOK3,RNF114 |
| 3.267e-02 | -3.42 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 186 | 33 | 17758 | 2279 |
ADAM19,C16orf45,BHLHE40,SLC6A8,YARS2,PCDH7,EIF2S2,SLC39A7,ME1,RNF2,PTGS1,PNPLA4,SAMD4A,NUDC,SAP30,RBCK1,FAM127A,FGF2,TFPI,ATXN1,NUDT15,CRYBG3,TARS,DKK1,NME7,KLF4,LARGE,SIL1,SLC16A1,COPS6,PDLIM5,FNBP1L,RBP1 |
| 3.267e-02 | -3.42 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDM_DN | 186 | 33 | 17758 | 2279 |
EFNB2,MCM6,MCM10,PAFAH1B1,TMEM183A,RSL1D1,PRKCA,SLC6A8,TTC1,MET,HN1,TMLHE,TIMM50,SAP30,RFC3,SKAP2,RAP1B,RNH1,MAP7D1,FKBP3,TCF7L2,ISG15,TIMM44,RARS,GTF2A1,FAM114A2,AGTPBP1,SRD5A3,SOCS4,USP20,ZNF18,SLC25A26,KAT6A |
| 3.267e-02 | -3.42 | GSE17721_POLYIC_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDM_DN | 186 | 33 | 17758 | 2279 |
SRM,HERC2,DNAJC2,ADAM19,POLR1A,CENPB,TTI1,PIBF1,RHBDD1,NOP56,POLR3D,PEX7,COPS3,IGF2BP1,LYRM5,LSM10,TSHZ1,STAG1,WLS,CAV1,UBE2K,CLNS1A,HERPUD1,KIF16B,KPNA1,SYNCRIP,TP53BP1,DNAJA3,NCBP2,BPNT1,GPAM,HEATR1,PREPL |
| 3.271e-02 | -3.42 | tube closure | biological process | GO:0060606 | 88 | 18 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SKI,APAF1,BMP4,PRKACB,MTHFD1 |
| 3.271e-02 | -3.42 | organic acid transmembrane transport | biological process | GO:1903825 | 88 | 18 | 16441 | 2138 |
SLC6A16,SLC38A6,SLC38A1,PRKAB2,SLC25A12,SLC6A8,CPT1A,SLC1A1,MPC1,SLC25A20,SLC7A1,SLC38A5,SLC7A11,SLC38A2,SLC16A1,SLC27A5,SLC25A26,SLC43A1 |
| 3.273e-02 | -3.42 | MOOTHA_PGC | MSigDB lists | MOOTHA_PGC | 405 | 65 | 17758 | 2279 |
PTCD2,NDUFA5,SUCLG1,PDK4,UROD,NDUFB5,LPIN1,FDX1,MAP2K3,NDUFB3,ME1,NDUFA6,LONP1,VPS13B,SKIV2L,ACADS,UPP1,HSPA5,OSBPL1A,TIMM44,HSDL2,DNAJA3,TIMM17A,HSPB8,SLC25A11,PUS1,NRP1,TXN2,ZNF589,SLC12A7,VIPR1,HSD17B10,FARS2,ID2,PLA2G12A,JMJD6,RTN4,ETFB,SLC25A20,DDIT4,TTC1,SNW1,SCN1B,COPS3,NDRG4,IFRD1,TIMM8B,NAA38,WDR61,IDH3G,EIF4A2,LDHA,ADSL,TBRG4,MARS,RANGAP1,CPT1A,ABCF1,UBC,MTHFD2,NME7,KIDINS220,NSF,TBL1X,NDUFS5 |
| 3.276e-02 | -3.42 | OXFORD_RALA_OR_RALB_TARGETS_UP | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_UP | 47 | 11 | 17758 | 2279 |
FARSA,EXOSC2,ASNS,MCM5,H2AFX,EXOSC4,MCM2,DKC1,ERI3,HN1,PGD |
| 3.276e-02 | -3.42 | NIKOLSKY_BREAST_CANCER_16Q24_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_16Q24_AMPLICON | 47 | 11 | 17758 | 2279 |
CTU2,BANP,ZCCHC14,SPATA2L,ZC3H18,ANKRD11,APRT,DPEP1,KLHDC4,CENPBD1,CPNE7 |
| 3.277e-02 | -3.42 | DDX21 (DEAD (Asp-Glu-Ala-Asp) box helicase 21) | protein interactions | 9188 | 104 | 22 | 16036 | 2270 |
CUL7,CUL4A,FN1,SIRT7,NFIA,RSL1D1,CSNK2A1,APTX,SON,NOP56,DOT1L,DDX50,CTNNBL1,KPNA3,HNRNPR,H2AFX,SRRM2,ZC3H3,FTSJ3,TERF2,TOP1,SRPK2 |
| 3.277e-02 | -3.42 | SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1) | protein interactions | 6602 | 104 | 22 | 16036 | 2270 |
DPF3,ARID2,DPF2,RPS29,SMARCD3,SMARCA4,ARID1A,ARID1B,KDM1A,SMARCB1,SMARCC1,TP53BP1,VPS37B,CCDC85B,UPF2,CORO1A,NCOR1,TBL1X,ANP32B,BRCC3,BRD9,CARM1 |
| 3.295e-02 | -3.41 | Metabolism of non-coding RNA | REACTOME pathways | R-HSA-194441 | 50 | 12 | 8202 | 1117 |
GEMIN5,RANBP2,NUP133,NCBP2,NUP43,GEMIN4,PRMT5,NUP160,NUP214,POM121,CLNS1A,SEH1L |
| 3.295e-02 | -3.41 | snRNP Assembly | REACTOME pathways | R-HSA-191859 | 50 | 12 | 8202 | 1117 |
GEMIN5,RANBP2,NUP133,NCBP2,NUP43,GEMIN4,PRMT5,NUP160,NUP214,POM121,CLNS1A,SEH1L |
| 3.304e-02 | -3.41 | negative regulation of protein ubiquitination | biological process | GO:0031397 | 132 | 25 | 16441 | 2138 |
UBXN1,TEX14,SMAD7,NXN,PSMA1,CAV1,SOX4,PSMF1,HSPA1A,UBR5,MAD2L2,UBC,UBE2E1,ISG15,HSPA1B,ABL1,ANAPC1,KLHL22,CDC16,ANAPC11,ANAPC10,MAD1L1,ATM,PRMT3,ANAPC4 |
| 3.307e-02 | -3.41 | BLOC-1 complex | cellular component | GO:0031083 | 15 | 5 | 17570 | 2233 |
SNAP25,BCAS4,BLOC1S4,DTNBP1,BLOC1S2 |
| 3.310e-02 | -3.41 | positive regulation of cell cycle | biological process | GO:0045787 | 311 | 52 | 16441 | 2138 |
HMGA2,CUL4A,PAFAH1B1,ANKRD17,ATRX,TCF3,PLRG1,PBX1,ID2,CSPP1,PPP1R1C,CCNL2,SIRT2,PRKCA,TGFB2,GDPD5,PSMF1,PRKCE,ASNS,ANAPC11,TRIAP1,WIZ,RDX,LSM10,DMRT1,C6orf89,SRPK2,BRD4,MSX1,CRADD,CDK4,SMARCD3,PSMA1,BRCA1,SOX4,PLCB1,UBC,FGFR1,ANXA1,DDX3X,MSX2,BRCA2,MYBBP1A,GATA6,CCNT1,NSMCE2,TBX3,RAD51B,FNTB,SVIL,ATM,RPS6KB1 |
| 3.310e-02 | -3.41 | peptidyl-lysine acetylation | biological process | GO:0018394 | 113 | 22 | 16441 | 2138 |
KAT8,WDR75,EP400,BRD4,TRIM16,TAF1,TCF3,ELP3,ATAT1,CHD5,TADA3,SRCAP,TRRAP,BRCA2,KANSL1,PER1,MED24,POLE3,TAF12,KMT2A,YEATS2,KAT6A |
| 3.313e-02 | -3.41 | XPNPEP1 (X-prolyl aminopeptidase (aminopeptidase P) 1, soluble) | protein interactions | 7511 | 70 | 16 | 16036 | 2270 |
DMGDH,GARS,ATP6V1A,VTA1,ADSL,MARS,MTHFD1L,NOL3,UBC,CIAPIN1,WARS,RNF40,DCTPP1,ASNS,UCHL5,MTHFD1 |
| 3.317e-02 | -3.41 | histone demethylase activity (H3-K4 specific) | molecular function | GO:0032453 | 6 | 3 | 16491 | 2164 |
KDM5C,KDM5B,KDM1A |
| 3.317e-02 | -3.41 | MAP-kinase scaffold activity | molecular function | GO:0005078 | 6 | 3 | 16491 | 2164 |
SPAG9,DUSP19,MAPK8IP3 |
| 3.317e-02 | -3.41 | C3HC4-type RING finger domain binding | molecular function | GO:0055131 | 6 | 3 | 16491 | 2164 |
KCNH2,HSPA1A,HSPA1B |
| 3.317e-02 | -3.41 | histone methyltransferase activity (H3-K36 specific) | molecular function | GO:0046975 | 6 | 3 | 16491 | 2164 |
NSD1,ASH1L,SETD2 |
| 3.317e-02 | -3.41 | histone methyltransferase activity (H3-K9 specific) | molecular function | GO:0046974 | 6 | 3 | 16491 | 2164 |
SUV39H2,EHMT2,EHMT1 |
| 3.318e-02 | -3.41 | RPL14 (ribosomal protein L14) | protein interactions | 9045 | 218 | 41 | 16036 | 2270 |
NIFK,CUL7,FN1,URB2,TCF3,SIRT7,URB1,NOP56,DDX56,RPS16,NVL,SCAF1,PAK1IP1,DDX31,RNF2,NOC3L,ZCCHC7,CDK12,PABPC1,FTSJ3,HNRNPM,ZNF629,RPS6KB2,DDX24,GLTSCR2,GNL3,MINA,DKC1,RBM28,C8orf33,PUM3,GZF1,ZFP62,MYBBP1A,RPL28,COPS5,CEBPZ,CUL2,FUS,SRP14,ZBTB24 |
| 3.324e-02 | -3.40 | PPP6R3 (protein phosphatase 6, regulatory subunit 3) | protein interactions | 55291 | 59 | 14 | 16036 | 2270 |
TERF2IP,USP7,USP49,SIRT7,USP10,ENAH,RNF2,BRCA1,AP1B1,TPM1,USP36,ECH1,RPS6KB2,CDC37 |
| 3.324e-02 | -3.40 | KLHL20 (kelch-like family member 20) | protein interactions | 27252 | 59 | 14 | 16036 | 2270 |
CTU2,UBAP2,EIF2S2,HELZ,PRIM2,MIOS,NARS,PCMT1,ADSL,IPP,SATB2,ARHGEF12,CEP126,COPS6 |
| 3.327e-02 | -3.40 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1443 | 208 | 17775 | 2278 |
ARHGAP26,POLB,THOC5,NF1,PRKAB2,HECTD3,CSNK2A1,RNF43,HLTF,PRKCA,LPAR3,UBR5,BIRC2,MAP2K3,WNT2B,GIPR,SMARCB1,ABL2,EXOC1,RAP1A,PMAIP1,JAZF1,XRCC2,ANAPC11,NCKIPSD,MAD1L1,RELB,JOSD1,RAN,ETV1,ZMYM2,OGG1,CDK6,PRKACB,CDC37,DBN1,RBCK1,NRAS,PPARG,CDK4,KSR2,CAV1,BRCA1,SGK2,MLLT10,SH3GL1,SPOP,RHOU,TCF7L1,BRCA2,SUFU,RAD18,SH3RF1,PER1,SOCS4,TNFRSF1A,RAD51B,DIRAS1,RUNX1,CCNB1IP1,MAGI1,NRP1,COPS6,FIP1L1,ZNF598,USP15,LPP,MEF2C,CARS,FBXO45,FOXO1,CELSR1,LAMTOR3,MAPK8IP3,PIK3R4,PCSK7,TGFBR2,CDC73,PRKCE,ELL,UBE3A,USPL1,ATIC,MYC,GTF2H1,WNT16,PEA15,MSI2,SIK3,GTF2H3,PDE4A,USP49,PRDM16,TLE3,RAP1B,LIG4,USP10,ARID1A,TRIM37,USP46,TCF7L2,IRS1,SPAG9,PALB2,SQLE,DDX10,PRKAR2A,MAP2K4,TCF12,USP7,SPRED2,DLL4,ABCA3,CYLD,NTSR1,DDR2,SMARCA4,RIPK1,PBX1,PPP2R2A,FOSL2,LTB4R,RADIL,FLNB,SBDS,JAG1,SHC1,KDM2A,SOCS1,UCHL5,IKBKB,SOCS6,RNF2,TTC3,MSH4,MET,KMT2A,CDK12,CASP10,MAML3,PMS1,BRD4,PDK1,STAMBP,PARP2,MARCH6,MEF2D,NUP214,STK10,ERC1,EIF3H,FGFR1,USP36,EXO1,RANBP2,RBBP8,COPS5,ACP1,RPS6KB1,TRAF3,FUS,USP11,BRCC3,SEPT5,MUTYH,SMG1,TRIM36,BCKDK,BRAF,XPC,TCF3,MLH1,TGFB2,CSNK1A1,FOXO3,NEDD4,MAD2L2,ABL1,LTN1,FBXL19,RPS6KB2,TOP1,FGF9,PXN,APEX1,ADAMTSL3,FGF2,FZD3,TEX14,RAP1GDS1,ARHGEF12,MEN1,KLF6,PIK3CB,DKK1,ZRANB3,HERC1,SET,MSH3,DNAJC12,USP20,ATM,RBPJ,BMP4,NFKBIB,RABEP1,DDIT3,STK4 |
| 3.329e-02 | -3.40 | stomach-carcinoma-undifferentiated_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-undifferentiated_adenocarcinoma | 53 | 12 | 17775 | 2278 |
ABL1,BRAF,NRAS,NF1,ATM,MLH1,BRCA1,ARID1A,KMT2C,MET,FGFR1,SMARCB1 |
| 3.329e-02 | -3.40 | undifferentiated_adenocarcinoma | COSMIC cancer mutations | undifferentiated_adenocarcinoma | 53 | 12 | 17775 | 2278 |
ABL1,BRAF,NRAS,NF1,ATM,ARID1A,MLH1,BRCA1,KMT2C,MET,FGFR1,SMARCB1 |
| 3.334e-02 | -3.40 | Znf_C3HC4_RING-type | interpro domains | IPR018957 | 59 | 13 | 18293 | 2341 |
PCGF3,TRIM13,RAD18,SH3RF1,RNF138,TRIM15,RNF2,BRCA1,BMI1,MID1,RING1,TRIM36,RNF114 |
| 3.340e-02 | -3.40 | human chr13q12.3 | chromosome location | human chr13q12.3 | 19 | 5 | 26250 | 2590 |
SLC7A1,BRCA2,USPL1,KATNAL1,PDS5B |
| 3.340e-02 | -3.40 | human chr7q31 | chromosome location | human chr7q31 | 19 | 5 | 26250 | 2590 |
IMMP2L,WNT16,MET,EXOC4,COG5 |
| 3.340e-02 | -3.40 | human chr2q14.2 | chromosome location | human chr2q14.2 | 19 | 5 | 26250 | 2590 |
PTPN4,TMEM177,INSIG2,CFAP221,C2orf76 |
| 3.341e-02 | -3.40 | pancreas-carcinoma-adenocarcinoma | COSMIC cancer mutations | pancreas-carcinoma-adenocarcinoma | 533 | 83 | 17775 | 2278 |
KCTD7,RAB11FIP4,BCAS4,PCNT,TRIM16,NF1,PSTPIP2,TNFRSF21,OSBPL9,FANCD2,BCOR,PLXNB1,FRRS1,PRKD3,SLX4,MMP7,MPHOSPH10,SREBF2,ZFHX3,NSRP1,NUP133,ZFYVE28,UBR1,PDS5B,MYH15,ANO8,SSBP1,CDK6,LYST,SEH1L,LAMA4,FLNC,FAM111B,EIF3J,GRHL3,NLN,WDHD1,ZSCAN2,UBR4,BRCA2,NSMCE2,ITGA2,C3orf35,BRD9,PTPN14,ANKRD17,SUPT6H,PRSS3,NKD2,DNAJC22,SLC1A1,PRKCH,NEBL,ABCA5,ASAP1,USPL1,PDE10A,LTN1,N4BP2,DNMBP,ERICH1,SYNGAP1,PRDM16,ELP3,ZC3H18,PLAC8L1,LDHA,PTPN12,TTYH2,SUPT5H,RHOT2,KLF6,CPT1A,ACOXL,SMPDL3B,SLC23A2,ZNF708,LRP1B,ATM,KIAA0196,POLR1C,MAP2K4,C6orf223 |
| 3.344e-02 | -3.40 | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | 193 | 34 | 17758 | 2279 |
IMMP2L,KHDRBS1,PPHLN1,GYG1,KDM1A,NOP56,CAD,FARSA,NISCH,LONP1,HTRA2,SLC25A1,NIPSNAP1,MCEE,CHD9,TIMM8B,SIGMAR1,JMJD1C,MEX3B,MTHFD1L,PDE2A,POLR3G,POP1,TPD52L2,ETFDH,INSIG1,KIDINS220,SUFU,CDK9,TBL1X,XPO6,DMTF1,SLC25A26,SMG1 |
| 3.344e-02 | -3.40 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDM_DN | 193 | 34 | 17758 | 2279 |
ASCC1,MCM10,CAMK1,GYG1,XPO7,RSRC1,DECR1,RAP1A,ARHGAP18,NOP16,GLTP,CORO1A,RAN,ANP32B,NT5M,LYPLA2,ELOF1,ZBED4,MINA,GMFB,PSMA1,TOR1AIP2,C19orf70,MGAT2,GNG2,TOE1,GTF2A1,SERF2,ASTN2,ARNTL,BPNT1,ZNF18,PTP4A2,BAG1 |
| 3.344e-02 | -3.40 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP | 193 | 34 | 17758 | 2279 |
KCTD7,NCOR2,MCM6,UBN1,PLRG1,C16orf45,SLC6A8,PABPC4,FLNB,TTC1,ABL1,ASNS,SYN2,ATIC,TOMM34,PABPC1,PMS1,FAM172A,CDK4,TRA2A,MARCKSL1,IMPDH2,MCM2,GPNMB,STK10,STOML2,UBTF,SLC39A14,TPD52L2,KPNA3,GADD45A,TRAP1,USP20,DDIT3 |
| 3.344e-02 | -3.40 | GSE17721_CTRL_VS_CPG_1H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_1H_BMDM_UP | 193 | 34 | 17758 | 2279 |
ZCCHC8,TMEM183A,CLINT1,SLC39A11,TTC1,NPRL2,ENTPD5,NCKIPSD,TNPO3,EXOSC4,TMEM14C,TIMM50,NRAS,ZNF124,TUBA1A,CLYBL,PPP1R21,SUMO3,RNH1,MCM2,EIF5B,SLC50A1,STOML2,HLA-DMA,PES1,HPRT1,IREB2,ELP2,ADAT2,HIC2,SVIL,ZFP90,NCOR1,SLC25A26 |
| 3.344e-02 | -3.40 | GSE17721_LPS_VS_CPG_16H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_16H_BMDM_UP | 193 | 34 | 17758 | 2279 |
FAM208B,AUH,CCDC53,TRAK1,C1orf52,SSBP2,DNAH1,MRPS11,IQGAP2,SLC30A7,PTPN2,ATXN7L1,NUP133,AMOT,LAMA4,MSX1,AEBP2,IFNGR2,TEX19,TOP3A,METTL23,NXN,LRRC8A,TPRA1,PEAK1,FOXRED1,TOE1,PMEPA1,ZBTB12,ZCCHC6,DNAJC12,ZC3H8,BMI1,DOCK6 |
| 3.344e-02 | -3.40 | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | MSigDB lists | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | 193 | 34 | 17758 | 2279 |
VMA21,TCF12,ADAM19,FAM122B,MLH1,AP1B1,GBF1,CMTM3,FLNB,LYPLAL1,DNAJB6,SAMD11,KDELC1,HIRIP3,MTHFD1,FADS1,TRIM13,ATF4,LIMA1,HSPA5,EYA3,HERPUD1,ARIH2,ZRANB3,PLIN2,EPRS,FAM135A,DNAJC1,MKL2,HIC2,GPAM,MB21D2,IPO4,RBP1 |
| 3.344e-02 | -3.40 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 193 | 34 | 17758 | 2279 |
TCF12,MCM6,ACTG1,NF1,CSNK2A1,SMARCA4,RNASEH2B,ETFB,NEDD4,IGF2BP3,PTPN2,MCAM,DNAJB6,ATIC,DSG2,YARS,GARS,ZC4H2,POLA1,ABCF2,LDHA,CUX1,WDHD1,MARCKSL1,ARHGAP32,SOX4,SNCA,CHAF1A,TP53BP1,PSAP,RWDD2B,EIF2B3,ADK,YEATS2 |
| 3.346e-02 | -3.40 | positive regulation of protein binding | biological process | GO:0032092 | 70 | 15 | 16441 | 2138 |
ABL2,ABL1,FKBP1A,TRIB3,HIPK2,PACS1,RAN,BMP4,CAV1,MEN1,NRP1,HERPUD1,TCF7L2,MEF2C,STK4 |
| 3.351e-02 | -3.40 | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP | 77 | 16 | 17758 | 2279 |
PFKFB4,TUBA1A,KCNMA1,C11orf80,LDHA,PSMA1,BHLHE40,ABHD6,FOXC1,CHAF1A,PAIP2,ASNS,CEP290,ZNF330,SQLE,TBXA2R |
| 3.355e-02 | -3.39 | human chr5q13.2 | chromosome location | human chr5q13.2 | 32 | 7 | 26250 | 2590 |
GUSBP3,PTCD2,GTF2H2C,MARVELD2,AK6,UTP15,MRPS27 |
| 3.359e-02 | -3.39 | WANG_LMO4_TARGETS_UP | MSigDB lists | WANG_LMO4_TARGETS_UP | 336 | 55 | 17758 | 2279 |
SERINC5,PIGM,EPM2AIP1,ACTG1,TTC27,BTBD2,PRKCSH,RFX1,TCF3,MRI1,SLC2A1,MRPL10,PPHLN1,ENAH,CSPP1,BCOR,CSNK1A1,UBTD2,DDIT4,SUB1,NEK6,NEBL,ZNF326,PDS5B,TTC3,NRIP1,LPCAT1,OGG1,SERBP1,SSFA2,GDPD1,NFIA,C11orf80,PCMT1,PACRGL,NLN,PHACTR2,ARHGEF12,COTL1,ARRDC4,FOXRED1,RAB10,LYRM7,USP36,RHOU,GTF2A1,DNAJC1,HNRNPR,HIPK2,H2AFX,ZNF430,DMTF1,MIPOL1,N4BP2L2,NIT1 |
| 3.361e-02 | -3.39 | chr3p22 | MSigDB lists | chr3p22 | 53 | 12 | 17758 | 2279 |
VIPR1,PFKFB4,XYLB,OXSR1,EPM2AIP1,CMTM8,TRAK1,CSRNP1,C3orf35,SLC4A7,MLH1,TGFBR2 |
| 3.361e-02 | -3.39 | IKEDA_MIR1_TARGETS_UP | MSigDB lists | IKEDA_MIR1_TARGETS_UP | 53 | 12 | 17758 | 2279 |
EFNB2,DDX3X,BDNF,ARHGAP21,JAG1,SYNCRIP,ATP6V1A,CRIM1,HNRNPR,ARRDC3,RSBN1,PRKACB |
| 3.363e-02 | -3.39 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | MSigDB lists | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | 25 | 7 | 17758 | 2279 |
SMAD3,MEN1,CCNT1,CDK9,MYC,E2F4,SMAD7 |
| 3.363e-02 | -3.39 | chr10p13 | MSigDB lists | chr10p13 | 25 | 7 | 17758 | 2279 |
CCDC3,VIM,MCM10,SUV39H2,ARL5B,BMI1,NSUN6 |
| 3.363e-02 | -3.39 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | 25 | 7 | 17758 | 2279 |
ABL2,PTP4A1,FOSL2,KLF6,KIAA0232,ZSWIM6,CSRNP1 |
| 3.363e-02 | -3.39 | MODULE_371 | MSigDB lists | MODULE_371 | 25 | 7 | 17758 | 2279 |
ADAM9,SSBP1,MMP7,KHDRBS1,GMFB,RPA1,MMP14 |
| 3.365e-02 | -3.39 | SERPINB5 (serpin peptidase inhibitor, clade B (ovalbumin), member 5) | protein interactions | 5268 | 43 | 11 | 16036 | 2270 |
EIF2S2,PRDX6,NARS,ITPA,UCHL5,ZRANB2,EIF2A,C11orf54,PPIL3,ISG15,SF3A1 |
| 3.365e-02 | -3.39 | ALAS1 (5'-aminolevulinate synthase 1) | protein interactions | 211 | 43 | 11 | 16036 | 2270 |
EP400,TMSB10,STAMBP,OXLD1,DUSP19,RAP1B,USP20,C8orf33,PIK3CB,TMSB4X,CDC73 |
| 3.365e-02 | -3.39 | MYO1C (myosin IC) | protein interactions | 4641 | 43 | 11 | 16036 | 2270 |
RRN3,SHC1,NEK6,HNRNPR,KHDRBS1,DNAJA3,SIRT7,USP20,POLR1B,RPA1,RPS6KB2 |
| 3.365e-02 | -3.39 | SMU1 (smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)) | protein interactions | 55234 | 43 | 11 | 16036 | 2270 |
RANBP2,CUL7,KDM4B,FAM172A,LUC7L3,SIRT7,TFPI,ZC3H18,PHGDH,BMI1,RABEP1 |
| 3.365e-02 | -3.39 | DFFA (DNA fragmentation factor, 45kDa, alpha polypeptide) | protein interactions | 1676 | 43 | 11 | 16036 | 2270 |
NAP1L5,TUBA1A,TOM1L2,TSPYL4,ATG3,HERC1,FERMT2,SEPT5,BZW2,MAT2A,USP15 |
| 3.366e-02 | -3.39 | GCM_GSPT1 | MSigDB lists | GCM_GSPT1 | 160 | 29 | 17758 | 2279 |
KDM3B,CHD9,EPM2AIP1,BAZ2A,AARS2,HECTD3,FAN1,ATG2B,EHBP1,FOXO3,POGZ,VPS53,TAF9B,COMMD9,APBB3,KIDINS220,NUP133,CLEC16A,DCTN4,SOCS4,VPS52,FNTB,ASB3,RAN,TTC17,TBCK,BRD9,XPO6,COG5 |
| 3.366e-02 | -3.39 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | 160 | 29 | 17758 | 2279 |
FLNC,AOC3,SPRED2,NOSTRIN,ZFYVE1,KATNAL1,VSNL1,DDR2,C11orf80,MYH9,MSRB3,FERMT2,RTN4,RCAN1,CAV1,LAMA2,TTC28,NDUFV1,AHNAK,PTRF,KIDINS220,NME7,CNIH3,TTC3,RUNX1,SH3PXD2A,PTPN14,PERP,NAV3 |
| 3.368e-02 | -3.39 | oxidation-reduction process | biological process | GO:0055114 | 1017 | 152 | 16441 | 2138 |
IMMP2L,CYP24A1,GNB3,PRDX6,PRKAB2,PLOD1,GYG1,HMOX2,PRKCA,COX10,FRRS1,PCYOX1L,RAP1A,PHKA1,ATP5G2,SUCLG2,ME1,KDM5C,NDUFA6,FXN,PRKACB,ACADS,SESN2,ABCC4,PPARG,ALDH1L2,GNG7,MINA,MSRB3,MTHFD1L,FOXRED1,DLST,MGST1,PYCR1,MSRA,HSDL2,BDH2,TXN2,AOC3,OXNAD1,PAX2,HSD17B10,PID1,PHGDH,NDUFS7,ETFB,P3H1,MLX,HR,MYC,ALKBH8,ALDH18A1,AGL,FDFT1,MTHFD1,HSD17B14,HMGCR,FADS1,BDNF,TSTA3,PCCA,AOC2,JMJD1C,RAPGEF4,RDH10,IDH3G,TYW1,TBXAS1,SNAP25,IMPDH2,CPT1A,CYB5B,ACOXL,TCF7L2,PGD,RDH11,CAT,MYBBP1A,MTHFD2,GSTO2,ALKBH3,D2HGDH,SURF1,HK2,SQLE,PEX13,DHCR7,PRKAR2A,CPT1C,NDUFA5,SUCLG1,NDUFAF2,SLC2A1,NDUFB5,FDX1,KDM1A,NDUFB3,DECR1,DUS4L,KDM2A,CBR4,PYCRL,GLYR1,MTHFD2L,GNG5,TMLHE,MCEE,KDM3B,CPOX,POLG2,HSD3B7,SNCA,ATP5D,GNG2,KDM4B,DUS3L,DCXR,G6PD,PAM,ALKBH1,DMGDH,SLC25A12,JMJD6,ENOX1,ADH5,PEX7,NDUFV1,PTGS1,HSD17B12,MICAL3,PFKFB4,KDM6B,APEX1,KDM5B,KDM5A,LDHA,NXN,TBRG4,ADSL,MMAA,ECH1,UBC,RETSAT,ETFDH,PXDN,STX1A,ACOX1,COQ9,SRD5A3,NDUFAF5,NDUFS5,KDM4C |
| 3.376e-02 | -3.39 | MAPK signaling pathway | WikiPathways | WP382 | 163 | 29 | 4455 | 564 |
BDNF,BRAF,MINK1,MAP2K5,ATF4,NRAS,MAP3K13,NF1,HSPA5,RAP1B,LAMTOR3,MAPK8IP3,TGFB2,TGFBR2,HSPA1A,HSPA1B,PRKCH,RAP1A,GADD45A,MYC,IKBKB,PPP3CC,MAP3K14,MAP3K12,ZAK,MAP2K4,DDIT3,MAPT,MEF2C |
| 3.383e-02 | -3.39 | negative regulation of oxidative stress-induced cell death | biological process | GO:1903202 | 30 | 8 | 16441 | 2138 |
ATF4,TRAP1,HIF1A,PSAP,NOL3,MET,HTRA2,PYCR1 |
| 3.383e-02 | -3.39 | glutamate secretion | biological process | GO:0014047 | 30 | 8 | 16441 | 2138 |
GLS,BDNF,STX1A,NF1,SLC38A2,SNAP25,SYT1,SLC1A1 |
| 3.383e-02 | -3.39 | transcription elongation from RNA polymerase I promoter | biological process | GO:0006362 | 30 | 8 | 16441 | 2138 |
UBTF,GTF2H3,POLR1A,GTF2H1,POLR1B,POLR1C,ZNRD1,POLR1E |
| 3.383e-02 | -3.39 | positive regulation of histone methylation | biological process | GO:0031062 | 30 | 8 | 16441 | 2138 |
PAF1,SNW1,WDR61,PAXBP1,CTR9,BRCA1,KMT2A,MYB |
| 3.389e-02 | -3.38 | KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | MSigDB lists | KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | 134 | 25 | 17758 | 2279 |
HERC2,CUL4A,CUL7,BIRC6,ANAPC13,RCHY1,BRCA1,UBE2K,TRIM37,UBR5,BIRC2,NEDD4,UBE2E1,ANAPC1,UBE3A,CDC16,SOCS1,HERC1,CUL2,PPIL2,ANAPC11,ANAPC10,MID1,ANAPC4,PRPF19 |
| 3.389e-02 | -3.38 | JOHNSTONE_PARVB_TARGETS_2_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_UP | 134 | 25 | 17758 | 2279 |
PPP1R9B,TNIK,MINK1,ACTG1,DLGAP4,WWC1,ZNFX1,GRINA,COTL1,PLEK2,OASL,DDX60,ISG15,SMAD3,FKBP1A,ECM1,PTRF,GATA6,G6PD,GREB1,PCOLCE2,USP11,BRD9,SLC25A1,SPTAN1 |
| 3.389e-02 | -3.38 | WHITFIELD_CELL_CYCLE_S | MSigDB lists | WHITFIELD_CELL_CYCLE_S | 147 | 27 | 17758 | 2279 |
DMXL2,MYCBP2,INSIG2,PRIM2,POLA1,ANKRD18A,ABCC2,EFHC1,BRCA1,NUP160,SAP30BP,RMI1,LYRM7,CCDC150,EXO1,CDH24,RBBP8,SHC1,RAD18,INTS7,COQ9,SLC38A2,HSPB8,BIVM,KDELC1,BMI1,TMCC1 |
| 3.389e-02 | -3.38 | MORF_RUNX1 | MSigDB lists | MORF_RUNX1 | 147 | 27 | 17758 | 2279 |
EP400,CHD9,ATRX,SLC2A1,KIAA0586,SULT4A1,NFX1,KLHL18,BRCA1,TTI1,ERC1,PSMF1,PIK3CB,MGA,HTR7,TAF2,CACNB1,RBBP8,SLC30A3,TBC1D22A,NCKIPSD,MSH3,FNTB,SYNJ2,RUNX1,ZNF710,SMG1 |
| 3.394e-02 | -3.38 | cell-substrate junction assembly | biological process | GO:0007044 | 41 | 10 | 16441 | 2138 |
DST,COL17A1,PXN,LAMC1,FN1,TRIP6,FERMT2,ITGB4,LAMA5,PTPRK |
| 3.397e-02 | -3.38 | DHC_fam | interpro domains | IPR026983 | 15 | 5 | 18293 | 2341 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 3.397e-02 | -3.38 | MIF4-like | interpro domains | IPR016021 | 15 | 5 | 18293 | 2341 |
UPF2,MIF4GD,BZW2,CTIF,NOM1 |
| 3.397e-02 | -3.38 | Dynein_HC_stalk | interpro domains | IPR024743 | 15 | 5 | 18293 | 2341 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 3.397e-02 | -3.38 | ATP_grasp_subdomain_1 | interpro domains | IPR013815 | 15 | 5 | 18293 | 2341 |
SUCLG2,CAD,GART,SYN2,PCCA |
| 3.397e-02 | -3.38 | Dynein_heavy_dom | interpro domains | IPR004273 | 15 | 5 | 18293 | 2341 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 3.397e-02 | -3.38 | mitotic cell cycle | biological process | GO:0000278 | 802 | 122 | 16441 | 2138 |
CHMP2A,CUL7,CUL4A,PCNT,BIRC6,PAFAH1B1,PPP2R2A,CSNK2A1,SMARCA4,SIRT2,NUP43,PRKCA,NUP160,PIBF1,BIRC2,LPIN1,SBDS,SMARCB1,ANAPC1,NEK6,NUP133,XRCC2,ANAPC11,ANAPC10,MAD1L1,PDS5B,RNF2,CEP63,RAN,CEP135,CDK6,SEH1L,RFC4,RFC3,BRD4,TUBA1A,STAMBP,CDK4,ASUN,KIF15,ARHGEF10,HDAC8,MCM2,SOX4,TTC28,NUP214,TAF2,RHOU,TCF7L1,RANBP2,TRRAP,CDC16,RBBP8,MISP,E2F4,NSMCE2,RPS6KB1,NOLC1,CHMP4C,HMGA2,DCTN3,TTN,MCM6,ESCO1,MCM10,XPC,KHDRBS1,SIRT7,DBF4,ID2,CEP126,CSNK1A1,PSMF1,GIGYF2,POGZ,MAD2L2,POM121,SFI1,TADA3,ABL1,CEP164,CEP290,MCM5,BANF1,TRIAP1,TIMELESS,FBXO31,DIS3L2,NUDC,MYB,STAG1,PRIM2,GINS3,ANAPC13,APEX1,CRADD,PPAT,POLA1,FOXN3,HAUS6,TEX14,PSMA1,RANGAP1,HIST1H4J,MEN1,PLCB1,UBE2E1,UBC,CENPP,RPA1,DYNC1H1,KLHL22,POLE2,GADD45A,SDCCAG8,CUL2,ORC5,SET,ATM,PPP1R12B,BRSK2,ANAPC4 |
| 3.401e-02 | -3.38 | ACATATC,MIR-190 | MSigDB lists | ACATATC,MIR-190 | 59 | 13 | 17758 | 2279 |
TSHZ1,CHD7,GPHN,WDFY3,ASAP1,ACTR3,MEX3B,NFASC,SYNJ1,SAMD4A,TNRC6A,NAV3,TRIM36 |
| 3.401e-02 | -3.38 | MODULE_323 | MSigDB lists | MODULE_323 | 59 | 13 | 17758 | 2279 |
ZFAND3,SPAG9,NSF,NUP133,KHDRBS1,VTA1,HNRNPH3,JMJD1C,ZRANB2,RBPJ,TTC17,HSD17B12,TAF9B |
| 3.401e-02 | -3.38 | Height(PMID:18391952) | GWAS genes | Height(PMID:18391952) | 15 | 6 | 2389 | 419 |
SCMH1,HMGA2,CEP63,ADAMTSL3,UQCC1,CDK6 |
| 3.405e-02 | -3.38 | regulation of cell cycle process | biological process | GO:0010564 | 540 | 85 | 16441 | 2138 |
CHMP2A,THOC5,CUL7,CUL4A,BIRC6,ATRX,PLRG1,CSNK2A1,SMARCA4,PBX1,CSPP1,CCNL2,SIRT2,PDE3A,SBDS,TOM1L1,ANAPC1,NEK6,ANAPC11,ANAPC10,MAD1L1,WIZ,LSM10,CTC1,PRPF19,BRD4,TXLNG,CDK4,HDAC8,BRCA1,SOX4,DDX3X,MSX2,CAMK2D,CDC16,BRCA2,TOM1L2,GATA6,CCNT1,NSMCE2,RAD51B,CHMP4C,HMGA2,XPC,ANKRD17,TCF3,PIK3R4,PID1,ID2,PPP1R1C,RNASEH2B,GIGYF2,CDC73,PSMF1,MAD2L2,PRKCE,TRIAP1,RDX,FBXO31,PRMT5,DMRT1,CAV2,TERF2,PPP1R9B,MSX1,CRADD,FOXN3,TEX14,PSMA1,SMARCD3,TPRA1,MEN1,TRIM37,PLCB1,UBE2E1,ZNF655,UBC,ANXA1,KLHL22,MYBBP1A,CDK9,ATM,SVIL,BMP4,ANAPC4 |
| 3.407e-02 | -3.38 | lung-right_upper_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-adenocarcinoma | 10869 | 1433 | 17775 | 2278 |
ARHGAP26,ADAM19,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,SLC6A8,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,ABCC2,SLC9A5,SLC7A1,AHNAK,SSU72,RUNX1,ZNF532,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PITPNM1,RSPRY1,CHN1,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,SAMD3,ANGPT2,MYB,NOM1,RABEPK,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,USP10,MAP7D1,ST6GALNAC3,TRIM37,USP46,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,RPL28,EHMT2,BPNT1,KIAA0196,PDLIM5,RAB11FIP4,C16orf45,MAB21L3,DDR2,NUP43,LCLAT1,MCM9,RPGRIP1L,ZBED2,CD96,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,MSH4,MGLL,ZC3H3,DENND1A,LYST,KMT2D,ZNF480,SLCO6A1,PCNXL2,KCNH3,DSP,MAT2A,SLC39A14,FBXL5,ARHGAP21,ELP2,ASTN2,ARL13B,POLR3E,HOXA3,RPS6KB1,CEP170,CATSPERG,MAPT,RAB30,MORC2,HMGA2,ATG2B,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,TAF3,UNC13A,ACOT11,ANXA5,LTN1,C15orf41,SAMD4A,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,PPIP5K2,UBC,CCDC150,OXSR1,NSD1,SRCAP,HERC1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,TRIM16,WDR13,FAM13A,SCAF8,FRRS1,MAP2K3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,TRIML2,ZMYM2,SLC25A23,VPS13B,DSC3,FMNL3,RBCK1,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,LAMA2,KCNH2,DLST,CRYBG3,LSG1,CXADR,BSN,DYRK1B,LSS,CHD3,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,FOXO1,CLK1,ITFG1,NKD2,MAPK8IP3,FAN1,C1orf52,LYRM2,ARID1B,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,WNT16,PNPLA3,CWF19L2,SNX29,USP49,SETD2,OBSCN,MAPK1IP1L,METTL22,ACOXL,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,DDX10,SH3PXD2A,BCCIP,USP7,MPI,OLFM2,SUCLG1,ARID2,OSBPL9,NTSR1,LAGE3,RIPK1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,PLXNB1,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,VIM,CA5B,ZNF251,TJAP1,EXO1,KLF4,ATG7,INTS9,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,ADH5,SURF2,POLR1B,CPNE7,C12orf4,LRRIQ1,FOXN3,SMARCAD1,ABCF2,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,CDH24,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,USP20,RBM26,RBPJ,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,CSGALNACT2,SPAG6,ZNF646,GDAP1,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,TMEM206,PLCXD2,GNAI1,OSBPL1A,DOT1L,TRRAP,LSM14A,CCNT1,LUC7L3,HIC2,XPNPEP1,NRP1,WDR66,BLMH,BMI1,SPOCK3,SPOCK2,NMD3,CADM4,CDC42EP2,JUP,PRPF31,ST6GAL1,DLGAP4,TATDN3,PRPF39,MTUS1,TECTA,HR,USPL1,SCAF1,MYC,PIGG,CAV2,FDFT1,IFNGR2,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,MTR,ATP9B,ASCC3,MTHFD2,ALKBH3,VCAN,SPEN,MED15,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,BIRC6,KIAA0232,TMEM104,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,MRPS27,SHF,TTC3,CDK12,CASP8AP2,GON4L,PCMT1,PREX1,GNL1,SATB2,MARCH6,ERC1,HSD3B7,SNCA,ZBTB25,BAZ1A,CAMK2D,SMARCC1,G6PD,MBTD1,FTSJ1,LARGE,IFT140,SLC4A7,MID1,SSH2,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PSAT1,ZFYVE1,TMEM126B,AGPAT4,PACS1,BMS1,KLF6,SLC23A2,INF2,RETSAT,DDX50,COQ9,ATM,SVIL,APAF1,ADK,IPO4,IMMP2L,ZNF76,LETM1,EIF3C,ATRX,RARS2,PPIL1,PCYOX1L,DST,MYH3,GPATCH1,ZEB1,KIAA0922,HCFC2,YARS,CARM1,CEP128,DTNB,TNK2,FBXW4,SESN2,SKAP2,ZNF195,TFPI,VWCE,MINA,KSR2,COTL1,MTHFD1L,KMT2C,ST3GAL5,YTHDF2,TIMM44,CCDC3,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,DCAF5,MTCH1,RHOBTB1,ZCCHC8,VTA1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,PRF1,AKAP11,HSD17B14,ZNF629,ZNF234,ELOVL6,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,CORIN,HERPUD1,POP1,SYCP2L,BICD1,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,IFITM2,TBCK,FNBP1L,PDE9A,N4BP2L2,DMXL2,TNXB,SMARCA4,COBLL1,TMEM177,SPATS2,ARSJ,DHX35,ZC3H13,MPHOSPH10,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,PRAME,GRHL3,ATXN1,MRRF,METTL15,DKC1,EDEM2,UBR4,ARMC4,KPNA3,DUS3L,HNRNPR,CEBPZ,RNF130,NFRKB,BRD9,SMG1,TMEM33,SUPT6H,DYM,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,FAM49A,SEC24C,STC2,DCTN4,LDLRAD3,FBL,PKNOX1,MICAL3,TOP1,KDM6B,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,TMEM187,EIF5B,NAALADL2,CTIF,ZNF221,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NIT1,GNB3,ASCC1,CACNA1H,CSPP1,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,NSRP1,SYN2,RABGAP1L,FAAH2,PDS5B,ZNF148,HRG,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,PACRGL,RFX2,AKAP12,MSRB3,PLEKHM3,MCL1,C10orf76,RBM28,DDX3X,BRCA2,TMEM139,FIS1,RBP1,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,SIRT7,NHS,RSF1,CLINT1,YARS2,ABCA7,EIF2S2,SLC38A5,INTS7,MCM5,CACNB2,ZNF326,NOC3L,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,TOMM34,SERBP1,HMGCR,FADS1,TIMM8B,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,EVI5,ABCF1,NCDN,ZNF655,VPS13C,LRP1B,TASP1,GTF2A1,LEMD3,SURF1,ZNF160,GPN1,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,ACTR3,MYH9,AGAP6,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,KRT7,FAM111B,ARHGEF10,ADAM32,ATP6V0A1,FGFR1,PDE8B,HLA-DMA,TAF2,GNG2,IQCH,CDC16,PEMT,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,ZNF786,SERINC5,INSIG2,XPC,SESTD1,C1orf226,ID2,SF3A3,JMJD6,AKT1S1,RSRC1,KRI1,TADA3,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,ULBP1,DIS3L2,DDHD1,FBXO17,FGF9,ERICH1,CLYBL,ARHGAP39,R3HDM2,FAM126B,ZNF467,PDE3B,KISS1R,RARS,TOE1,TRIB3,BAZ2B,PXDN,STX1A,SLCO5A1,PTPN4,SLC25A19,PSAP,GPAM,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,UBAP2L,MPST,CDC37,SF3A1,PTPRK,TMPO,FLNC,CHD9,ZNF124,ABCC4,HARS,BAZ2A,SKIV2L2,NOL6,BRCA1,ZNF91,PEX1,KIF16B,GLS,MSRA,ZNF622,TP53BP1,PER1,TECPR2,CCDC146,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,SEPHS2,SARS,OXNAD1,AOC3,MCM6,LRRC28,ITPRIP,HSD17B10,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,LAMC1,CRADD,UTP15,WDR25,MEX3B,ZNFX1,SUPT5H,NR2F1,PWP1,ATXN7,SPAG9,ITPRIPL1,FAM135A,SYNCRIP,PALB2,DNAH17,ZNF430,PPP1R12B,ARHGAP12,PRKAR2A,KCTD7,NDUFA5,CYLD,LPCAT2,GPR143,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,METTL16,UBR1,FSIP2,DNAJB6,ARMC5,HIRIP3,HIBCH,RNF2,ZFP37,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SKIV2L,WDR36,PCGF3,NARS,CPOX,AKAP13,ENC1,NUP214,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,ZNF333,CLEC16A,ABHD3,ITGA2,ZNF436,TSSC1,PRRT3,ZNF18,NFASC,PPIL3,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,ZNF346,CSNK1A1,BZW2,ZNF594,IQGAP2,SACS,ANXA7,CWC27,PRICKLE2,HIST2H3D,GREB1,SELT,DDX31,CD44,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZNF654,ZMYM5,TEX14,DHX34,RAP1GDS1,PEAR1,GPNMB,RHOT2,CHCHD6,TMEM175,ARMC3,ZRANB3,POLR3G,GPC2,SRBD1,MSH3,GLG1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,MYCBP2,PRDX6,PLRG1,ENAH,ADAMTS6,UBR5,AARS,MGA,GIPR,RPS16,VPS52,ME1,CEP135,FUT11,SEH1L,TBC1D8,DDN,DPF3,SLC38A6,ATG9A,NR6A1,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,SEMA3F,FOXRED1,SKIL,ZNF81,VPS13D,SEMA3C,DNAH2,CCNB1IP1,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,ASAP1,COPS3,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,DDX28,SYNGAP1,KIAA0586,TTYH2,PLCB1,DAGLA,ZNF425,EPRS,KIDINS220,SRRD,PMEPA1,UBAP1,ZZEF1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MAP2K4,RTTN,PTCD2,AMOTL1,TRPM2,LIN28B,URB2,HFM1,NDUFB5,OLA1,KLHL18,AP1B1,FOSL2,SLC25A44,LTB4R,PDE3A,PAIP2,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,KDM2A,GLYR1,NBEA,KMT2A,PLEKHA4,ATP6AP1L,NAA35,RFC4,ZCCHC14,RFC3,MPP6,MTIF2,WDPCP,DLG4,KIAA1586,MED16,GALK2,PNN,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,ZNF236,ALKBH1,TRMT2A,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,FOXO3,NEDD4,MAD2L2,ZNF483,ZNF239,LRP2BP,TRIAP1,NISCH,PMPCA,HARS2,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,WDFY3,C19orf43,FZD3,KCNMA1,TBRG4,OASL,FBXO21,ZDHHC11,HELZ,RNF138,MYOM2,BRWD3,SLC43A1,LRRC41,SLC37A3,MVK,PHF3,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,ZNF107,SIRT2,SLC29A1,BCOR,STK33,SNAPC4,CUTC,AHCYL2,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,YLPM1,LONRF2,IPP,HYAL1,POLR3B,PCOLCE2,SLC27A5,CCDC121,PRKACB,TRIP13,LONP1,ELOF1,LAMA4,GPM6A,ZNF680,CMIP,SLC38A1,GPCPD1,CAV1,TCTN1,SERGEF,CDHR3,CHAF1A,TAF9B,PAF1,GEMIN5,TMEM132B,EPN2,GATA6,SUFU,TRMT5,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,VIPR1,SLC12A7,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,TOX4,CEP164,SIPA1L3,ATXN2,SEMA3D,NRIP1,N4BP2,CPSF3L,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,INTS5,RRAGA,EXOC4,HK2,ZFP90,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,CSTA,GBF1,VPS18,FARSA,BRE,CAMTA2,RPS6KL1,ZNF142,CPSF3,MET,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,MCEE,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,R3HDM1,ATP8B2,RAB10,TPK1,RAD54B,WARS,PLIN2,ZC3H12A,HYAL3,ADNP,SRFBP1,DISP1,SCARB1,HEATR1,USP11,KLHL24,TNIK,SULT1C2,DBF4,NSUN6,CLSTN2,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,DSG2,TANK,KDELC1,CLDND1,TTC17,AMOT,DMRT1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,PREPL,ZAK,MMP16,ARHGAP27,SLC16A10 |
| 3.407e-02 | -3.38 | right_upper_lobe | COSMIC cancer mutations | right_upper_lobe | 10869 | 1433 | 17775 | 2278 |
ARHGAP26,ADAM19,THOC5,ACTG1,DCP1B,AARS2,MRPL10,NAT10,TUBE1,SBF2,CCNL2,SLC6A8,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,SRRM2,FTSJ3,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,LIMA1,EXOC6B,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,ABCC2,SLC9A5,SLC7A1,AHNAK,SSU72,RUNX1,ZNF532,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PDCD7,PITPNM1,RSPRY1,CHN1,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,MRPL21,CCDC88C,SAMD3,ANGPT2,MYB,NOM1,RABEPK,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,USP10,MAP7D1,ST6GALNAC3,TRIM37,USP46,IRS1,DYNC1H1,TSR1,KPNA1,GSTO2,NME7,RPL28,EHMT2,BPNT1,KIAA0196,PDLIM5,RAB11FIP4,C16orf45,MAB21L3,DDR2,NUP43,LCLAT1,MCM9,RPGRIP1L,ZBED2,CD96,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,MSH4,MGLL,ZC3H3,DENND1A,LYST,KMT2D,ZNF480,SLCO6A1,PCNXL2,KCNH3,DSP,MAT2A,SLC39A14,FBXL5,ARHGAP21,ELP2,ASTN2,ARL13B,POLR3E,HOXA3,RPS6KB1,CEP170,CATSPERG,MAPT,RAB30,MORC2,HMGA2,ATG2B,TRIM22,RNASEH2B,PSMF1,TTLL11,SNW1,TAF3,UNC13A,ACOT11,ANXA5,LTN1,C15orf41,SAMD4A,RPL22L1,SPTAN1,VPS37A,DDX24,ZC4H2,ZC3H18,LDHA,NXN,RSBN1,PPIP5K2,UBC,CCDC150,OXSR1,NSD1,SRCAP,HERC1,SRD5A3,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,TRIM16,WDR13,FAM13A,SCAF8,FRRS1,MAP2K3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,TRIML2,ZMYM2,SLC25A23,VPS13B,DSC3,FMNL3,RBCK1,MIOS,PPARG,CDK4,ANK2,HSPA5,TSN,LAMA2,KCNH2,DLST,CRYBG3,LSG1,CXADR,BSN,DYRK1B,LSS,CHD3,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,PRPF4,TSEN2,MAGI1,BEND6,USP15,FOXO1,CLK1,ITFG1,NKD2,MAPK8IP3,FAN1,C1orf52,LYRM2,ARID1B,RNFT2,ZNF358,CEP290,MBD2,VPS72,NDRG4,WNT16,PNPLA3,CWF19L2,SNX29,USP49,SETD2,OBSCN,MAPK1IP1L,METTL22,ACOXL,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,DDX10,SH3PXD2A,BCCIP,USP7,MPI,OLFM2,SUCLG1,ARID2,OSBPL9,NTSR1,LAGE3,RIPK1,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,PLXNB1,NRF1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,VIM,CA5B,ZNF251,TJAP1,EXO1,KLF4,ATG7,INTS9,EIF2B3,FAHD1,MUTYH,PARD3,ZNF507,DMGDH,ESCO1,AUH,RFX1,APRT,VARS,RBM19,FOXP1,POGZ,ADH5,SURF2,POLR1B,CPNE7,C12orf4,LRRIQ1,FOXN3,SMARCAD1,ABCF2,TOP3A,FERMT2,ARHGEF12,RANGAP1,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,CDH24,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,BCAS3,USP20,RBM26,RBPJ,XPO6,KIF1B,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,ZFYVE28,SUCLG2,CHD2,CSGALNACT2,SPAG6,ZNF646,GDAP1,OSBP2,VSNL1,EFHC1,HIST1H2BL,ZDHHC14,SON,DENND4A,DDX60,TMEM206,PLCXD2,GNAI1,OSBPL1A,DOT1L,TRRAP,LSM14A,CCNT1,LUC7L3,HIC2,XPNPEP1,NRP1,WDR66,BLMH,BMI1,SPOCK3,SPOCK2,NMD3,CADM4,CDC42EP2,JUP,PRPF31,ST6GAL1,DLGAP4,TATDN3,PRPF39,MTUS1,TECTA,HR,USPL1,SCAF1,MYC,PIGG,CAV2,FDFT1,IFNGR2,RREB1,PRIM2,PCCA,RAPGEF4,RAP1GAP2,RDH10,RAP1B,ARID1A,TPRA1,EHBP1,MTR,ATP9B,ASCC3,MTHFD2,ALKBH3,VCAN,SPEN,MED15,ZCCHC6,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,BIRC6,KIAA0232,TMEM104,PTPRG,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,MRPS27,SHF,TTC3,CDK12,CASP8AP2,GON4L,PCMT1,PREX1,GNL1,SATB2,MARCH6,ERC1,HSD3B7,SNCA,ZBTB25,BAZ1A,CAMK2D,SMARCC1,G6PD,MBTD1,FTSJ1,LARGE,IFT140,SLC4A7,MID1,SSH2,BRAF,B4GALT5,FARS2,KIF5C,RCAN1,DNAJC22,OPA1,GIGYF2,FAM8A1,ABL1,NEBL,DYNC2H1,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PSAT1,ZFYVE1,TMEM126B,AGPAT4,PACS1,BMS1,KLF6,SLC23A2,INF2,RETSAT,DDX50,COQ9,ATM,SVIL,APAF1,ADK,IPO4,IMMP2L,ZNF76,LETM1,EIF3C,ATRX,RARS2,PPIL1,PCYOX1L,DST,MYH3,GPATCH1,ZEB1,KIAA0922,HCFC2,YARS,CARM1,CEP128,DTNB,TNK2,FBXW4,SESN2,SKAP2,ZNF195,TFPI,VWCE,MINA,KSR2,COTL1,MTHFD1L,KMT2C,ST3GAL5,YTHDF2,TIMM44,CCDC3,CC2D1B,FAM114A2,CTAGE5,CSMD3,ASB3,DCAF5,MTCH1,RHOBTB1,ZCCHC8,VTA1,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,PRF1,AKAP11,HSD17B14,ZNF629,ZNF234,ELOVL6,TRA2A,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,CORIN,HERPUD1,POP1,SYCP2L,BICD1,FAT1,FDPS,TMEM117,CDKAL1,SLC16A1,PFDN2,TBL1X,IFITM2,TBCK,FNBP1L,PDE9A,N4BP2L2,DMXL2,TNXB,SMARCA4,COBLL1,TMEM177,SPATS2,ARSJ,DHX35,ZC3H13,MPHOSPH10,PPFIBP1,SNTG2,ADCK4,ITGAX,TMEM120B,C6orf89,MAML3,NARS2,PRAME,GRHL3,ATXN1,MRRF,METTL15,DKC1,EDEM2,UBR4,ARMC4,KPNA3,DUS3L,HNRNPR,CEBPZ,RNF130,NFRKB,BRD9,SMG1,TMEM33,SUPT6H,DYM,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,FAM49A,SEC24C,STC2,DCTN4,LDLRAD3,FBL,PKNOX1,MICAL3,TOP1,KDM6B,DNMBP,FGF2,CRIM1,ZNF821,PSPC1,KDM5A,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,TMEM187,EIF5B,NAALADL2,CTIF,ZNF221,DAGLB,SERINC1,WDR35,AGTPBP1,VPS37B,ANKRD30BL,POLR1C,NIT1,GNB3,ASCC1,CACNA1H,CSPP1,NUP160,SYNJ1,NOS1AP,AMBRA1,PABPC4,PCDH7,NSRP1,SYN2,RABGAP1L,FAAH2,PDS5B,ZNF148,HRG,FXN,AVEN,CNTNAP3B,CDK6,PTPRM,PACRGL,RFX2,AKAP12,MSRB3,PLEKHM3,MCL1,C10orf76,RBM28,DDX3X,BRCA2,TMEM139,FIS1,RBP1,MEF2C,HERC2,CARS,EP400,CLDN15,TRIP6,SIRT7,NHS,RSF1,CLINT1,YARS2,ABCA7,EIF2S2,SLC38A5,INTS7,MCM5,CACNB2,ZNF326,NOC3L,PRMT5,CALN1,AGL,MAP3K12,ZNF518B,TOMM34,SERBP1,HMGCR,FADS1,TIMM8B,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EPS15L1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,EVI5,ABCF1,NCDN,ZNF655,VPS13C,LRP1B,TASP1,GTF2A1,LEMD3,SURF1,ZNF160,GPN1,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,NPAS2,ATP6V1A,ACTR3,MYH9,AGAP6,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,ABCA12,ZKSCAN1,FMNL1,GSTA4,CEP63,TMEM136,KRT7,FAM111B,ARHGEF10,ADAM32,ATP6V0A1,FGFR1,PDE8B,HLA-DMA,TAF2,GNG2,IQCH,CDC16,PEMT,HIPK2,WDR7,PAM,FUS,BRCC3,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,ZNF786,SERINC5,INSIG2,XPC,SESTD1,C1orf226,ID2,SF3A3,JMJD6,AKT1S1,RSRC1,KRI1,TADA3,NPRL2,SUV39H2,ACAP3,ARHGAP1,HNRNPM,ULBP1,DIS3L2,DDHD1,FBXO17,FGF9,ERICH1,CLYBL,ARHGAP39,R3HDM2,FAM126B,ZNF467,PDE3B,KISS1R,RARS,TOE1,TRIB3,BAZ2B,PXDN,STX1A,SLCO5A1,PTPN4,SLC25A19,PSAP,GPAM,NUDT22,DOCK6,CORO2B,KDM4C,ANAPC4,BCAS4,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,PHKA1,DHX33,MARVELD2,TRMU,XRCC2,UBAP2L,MPST,CDC37,SF3A1,PTPRK,TMPO,FLNC,CHD9,ZNF124,ABCC4,HARS,BAZ2A,SKIV2L2,NOL6,BRCA1,ZNF91,PEX1,KIF16B,GLS,MSRA,ZNF622,TP53BP1,PER1,TECPR2,CCDC146,RAD51B,SGSM2,DLX2,RNF214,CHMP4C,XYLB,SEPHS2,SARS,OXNAD1,AOC3,MCM6,LRRC28,ITPRIP,HSD17B10,BARX2,ZFP36L1,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,LAMC1,CRADD,UTP15,WDR25,MEX3B,ZNFX1,SUPT5H,NR2F1,PWP1,ATXN7,SPAG9,ITPRIPL1,FAM135A,SYNCRIP,PALB2,DNAH17,ZNF430,PPP1R12B,ARHGAP12,PRKAR2A,KCTD7,NDUFA5,CYLD,LPCAT2,GPR143,RNF24,LPCAT3,ZNF83,RPAIN,PELP1,KDM1A,CAD,METTL16,UBR1,FSIP2,DNAJB6,ARMC5,HIRIP3,HIBCH,RNF2,ZFP37,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,SKIV2L,WDR36,PCGF3,NARS,CPOX,AKAP13,ENC1,NUP214,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,ZNF333,CLEC16A,ABHD3,ITGA2,ZNF436,TSSC1,PRRT3,ZNF18,NFASC,PPIL3,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,ARFIP2,MAP1S,ZNF346,CSNK1A1,BZW2,ZNF594,IQGAP2,SACS,ANXA7,CWC27,PRICKLE2,HIST2H3D,GREB1,SELT,DDX31,CD44,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,ZNF654,ZMYM5,TEX14,DHX34,RAP1GDS1,PEAR1,GPNMB,RHOT2,CHCHD6,TMEM175,ARMC3,ZRANB3,POLR3G,GPC2,SRBD1,MSH3,GLG1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,MYCBP2,PRDX6,PLRG1,ENAH,ADAMTS6,UBR5,AARS,MGA,GIPR,RPS16,VPS52,ME1,CEP135,FUT11,SEH1L,TBC1D8,DDN,DPF3,SLC38A6,ATG9A,NR6A1,ALDH1L2,NOL8,EYA3,CUX1,TCEB3,SEMA3F,FOXRED1,SKIL,ZNF81,VPS13D,SEMA3C,DNAH2,CCNB1IP1,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,PRKCE,NAV1,PI4KB,ASAP1,COPS3,SLC16A9,GTF3C3,IGF2BP1,LPCAT1,PRPS1,TERF2,ADARB1,SCAF11,DDX28,SYNGAP1,KIAA0586,TTYH2,PLCB1,DAGLA,ZNF425,EPRS,KIDINS220,SRRD,PMEPA1,UBAP1,ZZEF1,ZBTB12,D2HGDH,PURB,PEX13,UMPS,IQSEC2,MAP2K4,RTTN,PTCD2,AMOTL1,TRPM2,LIN28B,URB2,HFM1,NDUFB5,OLA1,KLHL18,AP1B1,FOSL2,SLC25A44,LTB4R,PDE3A,PAIP2,PHC2,CHD7,FLAD1,ZNF827,TMEM184A,KDM2A,GLYR1,NBEA,KMT2A,PLEKHA4,ATP6AP1L,NAA35,RFC4,ZCCHC14,RFC3,MPP6,MTIF2,WDPCP,DLG4,KIAA1586,MED16,GALK2,PNN,TBC1D16,POLG2,STK10,DHX57,VDR,HTR7,ZNF236,ALKBH1,TRMT2A,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,UTP14A,TTC27,C10orf2,TCF3,ZNF280C,NFX1,SLC25A12,RTN4,MYNN,MON2,LIAS,MLH1,IKBKAP,FOXO3,NEDD4,MAD2L2,ZNF483,ZNF239,LRP2BP,TRIAP1,NISCH,PMPCA,HARS2,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,WDFY3,C19orf43,FZD3,KCNMA1,TBRG4,OASL,FBXO21,ZDHHC11,HELZ,RNF138,MYOM2,BRWD3,SLC43A1,LRRC41,SLC37A3,MVK,PHF3,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,PLOD1,ZNF107,SIRT2,SLC29A1,BCOR,STK33,SNAPC4,CUTC,AHCYL2,MRPS30,SMARCB1,WNT2B,RTN1,ZNF804A,SRPRB,ANAPC1,THADA,YLPM1,LONRF2,IPP,HYAL1,POLR3B,PCOLCE2,SLC27A5,CCDC121,PRKACB,TRIP13,LONP1,ELOF1,LAMA4,GPM6A,ZNF680,CMIP,SLC38A1,GPCPD1,CAV1,TCTN1,SERGEF,CDHR3,CHAF1A,TAF9B,PAF1,GEMIN5,TMEM132B,EPN2,GATA6,SUFU,TRMT5,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,DMTF1,TNRC6A,VIPR1,SLC12A7,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,MED13L,XPO7,C11orf54,PHGDH,RHBDD1,ETFB,TOX4,CEP164,SIPA1L3,ATXN2,SEMA3D,NRIP1,N4BP2,CPSF3L,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,PRDM1,DNAH14,ISG15,UBAP2,ATAD5,MYBBP1A,INTS5,RRAGA,EXOC4,HK2,ZFP90,PDSS2,C12orf45,C7orf26,ZBTB24,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,CSTA,GBF1,VPS18,FARSA,BRE,CAMTA2,RPS6KL1,ZNF142,CPSF3,MET,TSPAN14,ZNF460,TMEM14C,HTRA2,MOSPD1,TMLHE,MCEE,PHLDB2,COL5A2,PTBP2,FAM172A,TFCP2,PARP2,SFSWAP,R3HDM1,ATP8B2,RAB10,TPK1,RAD54B,WARS,PLIN2,ZC3H12A,HYAL3,ADNP,SRFBP1,DISP1,SCARB1,HEATR1,USP11,KLHL24,TNIK,SULT1C2,DBF4,NSUN6,CLSTN2,PPP1R1C,SFI1,HDDC2,MAN1A1,MRPS11,IL17RE,PRKCH,GART,DSG2,TANK,KDELC1,CLDND1,TTC17,AMOT,DMRT1,ANKMY2,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,RERE,MFN2,ZNF708,PREPL,ZAK,MMP16,ARHGAP27,SLC16A10 |
| 3.408e-02 | -3.38 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | MSigDB lists | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | 65 | 14 | 17758 | 2279 |
RANBP2,KPNA1,EIF4E3,KPNA3,NUP133,EIF4A2,NUP43,NUP214,ISG15,NEDD4,SEH1L,POM121,FLNB,UBE2E1 |
| 3.412e-02 | -3.38 | YYCATTCAWW_UNKNOWN | MSigDB lists | YYCATTCAWW_UNKNOWN | 180 | 32 | 17758 | 2279 |
USP7,ID1,PDE4B,DDR2,SMARCA4,ATF7IP,AP1B1,DNAJC22,GDPD5,NEDD4,IGF2BP3,CHD2,CORO1A,PPA1,ANGPT2,ZNF646,ZBTB17,GPM6A,FAM172A,TUBA1A,ELOVL6,NFIA,GRHL3,USP10,UBE2E1,ADNP,VCAN,TRMT2A,RUNX1,RBPJ,RAB30,GALE |
| 3.412e-02 | -3.38 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | 180 | 32 | 17758 | 2279 |
HERC2,SERINC5,C17orf80,PDE4B,NAT10,PCSK7,ST7L,PSMF1,PCYOX1L,HR,THADA,USPL1,XRCC2,VGF,KIAA0922,WNT16,TRIM14,TIMM50,ZNF646,RPS6KB2,SIK3,CAMKK2,ERICH1,GLTSCR2,RNMT,ABCC2,ZC3H12A,PES1,INF2,ZNF266,LMBR1L,DNAH17 |
| 3.415e-02 | -3.38 | rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | rosette-forming_glioneuronal_tumour | 15 | 5 | 17775 | 2278 |
BRAF,NRAS,MET,KIAA1549,FGFR1 |
| 3.415e-02 | -3.38 | skin-hip-malignant_melanoma | COSMIC cancer mutations | skin-hip-malignant_melanoma | 15 | 5 | 17775 | 2278 |
MYCBP2,ZNF827,BRAF,NF1,PLXNB1 |
| 3.415e-02 | -3.38 | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | 15 | 5 | 17775 | 2278 |
BRAF,NRAS,MET,KIAA1549,FGFR1 |
| 3.416e-02 | -3.38 | Interactions of Rev with host cellular proteins | REACTOME pathways | R-HSA-177243 | 34 | 9 | 8202 | 1117 |
RANBP2,NUP133,RANGAP1,NUP43,RAN,NUP160,NUP214,SEH1L,POM121 |
| 3.416e-02 | -3.38 | Interactions of Vpr with host cellular proteins | REACTOME pathways | R-HSA-176033 | 34 | 9 | 8202 | 1117 |
RANBP2,KPNA1,NUP133,BANF1,NUP43,NUP160,NUP214,POM121,SEH1L |
| 3.423e-02 | -3.37 | HAN_SATB1_TARGETS_DN | MSigDB lists | HAN_SATB1_TARGETS_DN | 420 | 67 | 17758 | 2279 |
GGT1,BCAS4,TNFRSF21,TMEM132A,ST3GAL6,CSTA,ZNF804A,DNAJB6,BCAP29,NDUFA6,SERPINH1,OGG1,DENND1A,AUP1,RBCK1,CAMSAP2,DENND4A,MGST1,MAT2A,CXADR,GNAI1,LSS,HYAL3,ATG7,TPM1,ECHDC1,TMEM158,LAMA5,EPM2AIP1,INSIG2,SULT1C2,CELSR1,STXBP6,PDE4B,RBM19,TGFB2,BHLHE40,NOL3,SLC1A1,NEDD4,DDIT4,FKBP1A,SLC7A11,MCAM,PDE10A,HMGCR,TTPAL,ADARB1,BDNF,ADSL,RANGAP1,RABAC1,GPNMB,TCF7L2,NR2F1,VPS13C,PXDN,TTC38,SLC16A1,ATM,SQLE,ZNF430,ZRANB2,TBL1X,DDX10,N4BP2L2,HRH1 |
| 3.430e-02 | -3.37 | submandibular | COSMIC cancer mutations | submandibular | 36 | 9 | 17775 | 2278 |
UBTF,SYCP2L,LRP1B,BRAF,NRAS,PRDM16,SPEN,CHD2,ZNF507 |
| 3.430e-02 | -3.37 | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | 36 | 9 | 17775 | 2278 |
BRAF,NRAS,CLCN6,BCOR,RNF130,MET,KIAA1549,FGFR1,GNAI1 |
| 3.432e-02 | -3.37 | LIG4 (ligase IV, DNA, ATP-dependent) | protein interactions | 3981 | 122 | 25 | 16036 | 2270 |
NOMO3,THOC5,ACTG1,DDX19A,AGO2,LDHA,PALLD,NEU1,WARS,GUSBP3,SRSF2,TP53BP1,APLF,ANAPC10,HIC2,ATM,IPP,ETF1,CLU,FIP1L1,XRCC4,ATP6V0D1,MICAL3,TOP1,FAM214A |
| 3.434e-02 | -3.37 | SIGNAL_SEQUENCE_BINDING | MSigDB lists | SIGNAL_SEQUENCE_BINDING | 15 | 5 | 17758 | 2279 |
PEX7,BRE,KPNA1,KPNA3,TOMM34 |
| 3.434e-02 | -3.37 | PID_CIRCADIAN_PATHWAY | MSigDB lists | PID_CIRCADIAN_PATHWAY | 15 | 5 | 17758 | 2279 |
TIMELESS,BHLHE40,NPAS2,PER1,ARNTL |
| 3.434e-02 | -3.37 | KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS | MSigDB lists | KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS | 15 | 5 | 17758 | 2279 |
MVK,IDI1,PDSS2,FDPS,HMGCR |
| 3.434e-02 | -3.37 | SH3_DOMAIN_BINDING | MSigDB lists | SH3_DOMAIN_BINDING | 15 | 5 | 17758 | 2279 |
PTPN12,ADAM9,EVL,ARHGAP27,MAPT |
| 3.437e-02 | -3.37 | protein transporter activity | molecular function | GO:0008565 | 100 | 20 | 16491 | 2164 |
RANBP6,AP4S1,XPO5,AP4B1,MCL1,XPO7,AP1B1,TIMM10,TMCO6,TIMM44,EIF4ENIF1,RAP1A,KPNA1,KPNA3,TIMM17A,TNPO3,AP2S1,XPO6,IPO4,IPO11 |
| 3.443e-02 | -3.37 | CCTGCTG,MIR-214 | MSigDB lists | CCTGCTG,MIR-214 | 227 | 39 | 17758 | 2279 |
TRPM2,MINK1,LUZP1,ZHX3,PAFAH1B1,KCNJ14,PCDH7,PHC2,RNF40,ATXN7L1,ARMC5,DNAJB6,SEC24C,JAZF1,NCKIPSD,RAPGEFL1,NRIP1,IPO11,LSM12,BAZ2A,SIGMAR1,SFSWAP,RAP1GAP2,MAPK1IP1L,MARCH6,USP46,PHF6,RAD54B,MLLT10,ZFAND3,SMARCC1,KPNA3,SNX24,PURB,IQSEC2,NRP1,MB21D2,MID1,MAPT |
| 3.455e-02 | -3.37 | NUFIP1 (nuclear fragile X mental retardation protein interacting protein 1) | protein interactions | 26747 | 93 | 20 | 16036 | 2270 |
SNU13,GPM6A,DNM3,ANK2,VSNL1,ATP6V0A1,BRCA1,SNAP25,HIST1H2BL,PDE2A,SYT1,KLF6,SNCA,GNG2,GLS,STX1A,CCNT1,CDK9,NDRG4,MAPT |
| 3.457e-02 | -3.36 | circulatory system development | biological process | GO:0072359 | 774 | 118 | 16441 | 2138 |
IMMP2L,ADAM19,PTCD2,DLL4,CUL7,MAP2K5,ID1,LUZP1,MMRN2,NF1,MFGE8,MYH9,BCOR,PRKCA,RPGRIP1L,CHD7,CAD,JAG1,ECM1,SHC1,MMP14,CCDC40,HRG,SRPK2,FMNL3,PPARG,SIRT6,ANK2,WDPCP,COL4A3BP,CAV1,MEF2D,SOX4,DSP,FLVCR1,FGFR1,CXADR,WARS,SMAD3,ZC3H12A,MSX2,CAMK2D,GATA6,MKL2,ARL13B,ATG7,HOXA3,SLC4A7,SEMA3C,ANXA2,NRP1,TPM1,LAMA5,PTPN14,MEF2C,TNNC1,EFNB2,TTN,IFT57,EGR1,FOXO1,FN1,ANKRD17,SMAD7,ID2,RTN4,ZFP36L1,JMJD6,SEMA3E,TGFB2,TGFBR2,NEDD4,RBM20,FKBP1A,MCAM,NEBL,DSG2,NDRG4,ANP32B,WNT16,ERRFI1,AMOT,SOX6,PKNOX1,ANGPT2,MTHFD1,KDM6B,FGF9,MSX1,WARS2,FGF2,RB1CC1,SETD2,RYR2,SMARCD3,NXN,PRDM1,ARID1A,PTK2,PDE3B,ANGPTL4,FOXC1,PIK3CB,TCF7L2,HIF1A,VCAN,LEMD3,TBX3,BCAS3,ATM,RBPJ,BMP4,NR2F2,DHCR7,PDLIM5,DDIT3,STK4,KAT6A |
| 3.457e-02 | -3.36 | cardiovascular system development | biological process | GO:0072358 | 774 | 118 | 16441 | 2138 |
IMMP2L,ADAM19,PTCD2,DLL4,CUL7,MAP2K5,ID1,LUZP1,MMRN2,NF1,MFGE8,MYH9,BCOR,PRKCA,RPGRIP1L,CHD7,CAD,JAG1,ECM1,SHC1,MMP14,CCDC40,HRG,SRPK2,FMNL3,PPARG,SIRT6,ANK2,WDPCP,COL4A3BP,CAV1,MEF2D,SOX4,DSP,FLVCR1,FGFR1,CXADR,WARS,SMAD3,ZC3H12A,MSX2,CAMK2D,GATA6,MKL2,ARL13B,ATG7,HOXA3,SLC4A7,SEMA3C,ANXA2,NRP1,TPM1,LAMA5,PTPN14,MEF2C,TNNC1,EFNB2,TTN,IFT57,EGR1,FOXO1,FN1,ANKRD17,SMAD7,ID2,RTN4,ZFP36L1,JMJD6,SEMA3E,TGFB2,TGFBR2,NEDD4,RBM20,FKBP1A,MCAM,NEBL,DSG2,NDRG4,ANP32B,WNT16,ERRFI1,AMOT,SOX6,PKNOX1,ANGPT2,MTHFD1,KDM6B,FGF9,MSX1,WARS2,FGF2,RB1CC1,SETD2,SMARCD3,RYR2,NXN,PRDM1,ARID1A,PTK2,PDE3B,ANGPTL4,FOXC1,PIK3CB,TCF7L2,HIF1A,VCAN,LEMD3,TBX3,BCAS3,ATM,RBPJ,BMP4,NR2F2,DHCR7,PDLIM5,DDIT3,STK4,KAT6A |
| 3.458e-02 | -3.36 | HUMMEL_BURKITTS_LYMPHOMA_UP | MSigDB lists | HUMMEL_BURKITTS_LYMPHOMA_UP | 36 | 9 | 17758 | 2279 |
SERINC5,RFC3,PTBP2,TUBA1A,TCF3,RAP1GAP2,SMARCA4,SSBP2,RNASEH2B |
| 3.458e-02 | -3.36 | chr3p14 | MSigDB lists | chr3p14 | 36 | 9 | 17758 | 2279 |
EIF4E3,ARL6IP5,PRICKLE2,SUCLG2,FHIT,MAGI1,FOXP1,SLC25A26,FLNB |
| 3.458e-02 | -3.36 | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN | MSigDB lists | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN | 36 | 9 | 17758 | 2279 |
VPS52,VPS13D,NCOR1,POLR1C,PDE3B,CAV2,ARIH2,LYST,OSBPL1A |
| 3.458e-02 | -3.36 | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP | 36 | 9 | 17758 | 2279 |
SARS,PI4KB,SOCS1,PRIM2,ATP6V1A,PTPRA,ATP6V0A1,MAPT,SAP30 |
| 3.468e-02 | -3.36 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | 167 | 30 | 17758 | 2279 |
PTP4A1,C9orf78,IL11RA,RBM33,ITPRIP,TSPYL4,PTPRM,ARRDC3,RAP1GAP2,CUX1,MEF2D,SOX4,ENC1,TIGD1,TTC28,FAM8A1,ARIH2,PLCXD2,TMEM132B,SKIL,ARHGAP21,ZDHHC11,AHNAK,CNST,GADD45A,KLF4,MAD1L1,SOX6,SNX29,KAT6A |
| 3.476e-02 | -3.36 | REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION | MSigDB lists | REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION | 115 | 22 | 17758 | 2279 |
GTF2H3,POLR1A,POU2F1,HIST1H4J,HIST1H2BL,SNAPC4,POLR3A,UBTF,POLR3D,RRN3,PTRF,EHMT2,MBD2,POLR3E,H2AFX,GTF2H1,HIST2H3D,POLR3B,GTF3C3,POLR1B,POLR1C,SNAPC5 |
| 3.476e-02 | -3.36 | RUNX1 (runt-related transcription factor 1) | protein interactions | 861 | 76 | 17 | 16036 | 2270 |
TCF12,NCOR2,TCF3,SMARCA4,SMARCB1,HLA-DMA,VDR,SMAD3,SMARCC1,MYC,HIPK2,SPEN,NCOR1,RUNX1,KMT2A,CDK6,KAT6A |
| 3.476e-02 | -3.36 | MGMT (O-6-methylguanine-DNA methyltransferase) | protein interactions | 4255 | 76 | 17 | 16036 | 2270 |
DDX24,MYO7A,CSNK2A1,VIM,MCM2,PRKCA,EIF3H,ANXA1,PRKCH,BRCA2,SET,PTPN4,PRPF4,ANXA2,FBL,CDK12,TOP1 |
| 3.476e-02 | -3.36 | ATF7IP (activating transcription factor 7 interacting protein) | protein interactions | 55729 | 76 | 17 | 16036 | 2270 |
LAMA4,NOMO3,LAMC1,KRT7,ACTG1,MRI1,AP1B1,POLR2A,FLNB,TADA3,MCAM,SREBF2,GTF2H1,TTC3,SENP3,DMTF1,LAMA5 |
| 3.476e-02 | -3.36 | cardiac chamber morphogenesis | biological process | GO:0003206 | 101 | 20 | 16441 | 2138 |
TNNC1,PTCD2,DLL4,SMAD7,ID2,RYR2,SMARCD3,SOX4,DSP,FOXC1,FKBP1A,MSX2,JAG1,GATA6,HIF1A,TBX3,SEMA3C,RBPJ,TPM1,MEF2C |
| 3.481e-02 | -3.36 | GRADE_COLON_AND_RECTAL_CANCER_DN | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_DN | 96 | 19 | 17758 | 2279 |
SESN2,AOC2,PDK4,FAN1,MEF2D,RERE,SNCA,MSRA,SLC30A3,NAV1,UBAP1,GPR87,CFD,CYB5D1,HIC2,GREB1,SLC16A9,CDK12,PRKACB |
| 3.481e-02 | -3.36 | REACTOME_RNA_POL_II_TRANSCRIPTION | MSigDB lists | REACTOME_RNA_POL_II_TRANSCRIPTION | 96 | 19 | 17758 | 2279 |
GTF2H3,TAF1,RNMT,TCEB3,NFX1,SUPT5H,POLR2A,ELL,SRSF2,SUPT4H1,GTF2A1,CCNT1,CDK9,TAF4,GTF2H1,NCBP2,TAF12,CPSF3,LSM10 |
| 3.481e-02 | -3.36 | NAKAMURA_ADIPOGENESIS_LATE_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_UP | 96 | 19 | 17758 | 2279 |
ACSL5,FOXO1,PPARG,PTPRA,TNFRSF21,DYM,GMFB,NFIA,GAS6,TGFB2,LPIN1,PLIN2,ABL1,CCDC50,INSIG1,E2F4,MYC,PDE10A,MYB |
| 3.482e-02 | -3.36 | organic acid catabolic process | biological process | GO:0016054 | 211 | 37 | 16441 | 2138 |
XYLB,BCKDK,SDSL,AUH,HSD17B10,SLC25A21,LPIN1,ETFB,PCYOX1L,DECR1,PEX7,LPIN2,PHYKPL,HIBCH,PPM1K,TMLHE,MCEE,ACADS,SESN2,PPAT,ALDH1L2,PCCA,CPT1A,DLST,MMAA,ACOXL,ECH1,GLS,ETFDH,DDAH2,DCXR,ACOX1,BDH2,PEX13,DTD1,GCSH,CPT1C |
| 3.482e-02 | -3.36 | carboxylic acid catabolic process | biological process | GO:0046395 | 211 | 37 | 16441 | 2138 |
XYLB,BCKDK,SDSL,AUH,HSD17B10,SLC25A21,LPIN1,ETFB,PCYOX1L,DECR1,PEX7,LPIN2,PHYKPL,HIBCH,PPM1K,TMLHE,MCEE,ACADS,SESN2,PPAT,ALDH1L2,PCCA,CPT1A,DLST,MMAA,ACOXL,ECH1,GLS,ETFDH,DDAH2,DCXR,ACOX1,BDH2,PEX13,DTD1,GCSH,CPT1C |
| 3.483e-02 | -3.36 | MORF_RAC1 | MSigDB lists | MORF_RAC1 | 207 | 36 | 17758 | 2279 |
SEPHS2,SARS,PHF3,ANKRD17,XPC,KHDRBS1,CENPB,RTN4,XPO7,SSR4,UBR5,ATXN2,CFDP1,SEC24C,BANF1,UBAP2L,RAN,AHCYL1,ATP6V0D1,SNAPC5,NIPSNAP1,RBCK1,TSTA3,IDH3G,ATOX1,GMFB,ATG12,SERP1,RPA1,PWP1,YIF1A,COPS5,GLG1,NCBP2,XPO6,AP2S1 |
| 3.486e-02 | -3.36 | NDUFA10 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa) | protein interactions | 4705 | 38 | 10 | 16036 | 2270 |
RSPRY1,DECR1,BCKDK,NDUFV1,MTIF2,MPV17,ABCC2,RNF2,NDUFAF5,BRCC3 |
| 3.486e-02 | -3.36 | REST (RE1-silencing transcription factor) | protein interactions | 5978 | 38 | 10 | 16036 | 2270 |
SUB1,FBXW4,EHMT2,TEX14,SMARCA4,RNF2,NCOR1,KDM5C,UBC,TERF2 |
| 3.486e-02 | -3.36 | METTL1 (methyltransferase like 1) | protein interactions | 4234 | 38 | 10 | 16036 | 2270 |
SNU13,TPD52L2,UBE3A,APEX1,ACTR3,C15orf40,PDLIM5,AARS,IPO11,TOM1L1 |
| 3.486e-02 | -3.36 | HTATSF1 (HIV-1 Tat specific factor 1) | protein interactions | 27336 | 38 | 10 | 16036 | 2270 |
POP1,DYNC1H1,SUPT4H1,CCNT1,CDK9,ZNF512B,CSNK2A1,SUPT5H,PELP1,POLR2A |
| 3.488e-02 | -3.36 | MANN_RESPONSE_TO_AMIFOSTINE_UP | MSigDB lists | MANN_RESPONSE_TO_AMIFOSTINE_UP | 20 | 6 | 17758 | 2279 |
CAT,RFC4,ZFP36L1,XPC,MYC,CPOX |
| 3.488e-02 | -3.36 | CHEOK_RESPONSE_TO_MERCAPTOPURINE_DN | MSigDB lists | CHEOK_RESPONSE_TO_MERCAPTOPURINE_DN | 20 | 6 | 17758 | 2279 |
VAPB,NFASC,RBBP8,PRF1,SPOCK2,SOCS6 |
| 3.488e-02 | -3.36 | TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS | 20 | 6 | 17758 | 2279 |
UMPS,APRT,HPRT1,PPAT,SIRT6,UPP1 |
| 3.488e-02 | -3.36 | STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 20 | 6 | 17758 | 2279 |
MED24,MED16,ARID1A,UBR5,RBFOX2,PPARGC1B |
| 3.493e-02 | -3.35 | V$MYOD_Q6 | MSigDB lists | V$MYOD_Q6 | 234 | 40 | 17758 | 2279 |
SSH2,TTN,RHOBTB1,MAP3K13,TNFRSF21,TMEM109,HES6,CCNL2,FAM49A,MTUS1,ABL2,NRF1,HR,IKZF5,SREBF2,JAZF1,NCKIPSD,CELF1,IGF2BP1,HN1,DPF3,ALG6,AP4S1,LIMA1,ANK2,PSMC3IP,WWC1,KCNH2,PLCB1,ST3GAL5,EXOC6,SPOP,HTR7,ARL4A,RBM26,RBPJ,ITGB4,MAGI1,MID1,USP15 |
| 3.495e-02 | -3.35 | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | 187 | 33 | 17758 | 2279 |
XPC,APRT,HMOX2,RPS6KA5,PELP1,MFHAS1,PAG1,ATXN7L1,CD96,CNST,ATIC,PVRL3,FAAH2,MAP3K14,PNMA1,TMEM200A,RABEPK,CCDC57,EVL,GON4L,PCNXL2,ADSL,PHACTR2,ZNFX1,SLC35F2,MTHFD1L,ATP8B2,USP46,STOML2,TAF9B,RUNX1,NFRKB,MB21D2 |
| 3.495e-02 | -3.35 | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN | MSigDB lists | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN | 187 | 33 | 17758 | 2279 |
HM13,SHQ1,SUCLG1,CCDC53,ALG8,HMOX2,AARS,EEA1,TADA3,FAM192A,DECR1,RPS16,PPID,METTL8,TMPO,FAM120B,PMS1,TIMM8B,STAMBP,EIF3J,MTIF2,PPP1R21,PITPNB,CYB5B,ECH1,MRPL36,SPOP,MGAT2,SRCAP,TMCO1,ZBTB8OS,EIF2S1,MID1 |
| 3.495e-02 | -3.35 | GSE13306_RA_VS_UNTREATED_TCONV_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_TCONV_UP | 187 | 33 | 17758 | 2279 |
SDSL,CUL4A,BTBD2,FAM189B,VTA1,CERS5,LETMD1,ISG20L2,MFHAS1,DCTPP1,ZNF239,SUV39H2,ZSWIM7,ASAP1,GPATCH1,PRF1,FBXW4,ELOVL6,PARP2,TTYH2,SHISA5,PDE2A,LSG1,DDX49,PES1,APBB3,RANBP2,EEFSEC,PPP1R12B,TBL1X,PUS1,BRD9,PTPN14 |
| 3.495e-02 | -3.35 | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_DN | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_DN | 187 | 33 | 17758 | 2279 |
ARHGAP26,CLDN15,PRKCSH,SIRT7,CORO6,DENND3,MFHAS1,MTUS1,CHD7,HVCN1,ACD,TBC1D22A,IKBKB,MGLL,COQ3,ACTR3B,DENND1A,ZBTB17,C21orf58,CRADD,MYO10,ARHGEF10,ENC1,ANGPTL4,CCDC150,ANXA1,SH3GL1,INSIG1,INTS5,LARGE,TMEM219,NAPA,LPP |
| 3.495e-02 | -3.35 | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDM_DN | 187 | 33 | 17758 | 2279 |
CARS,BANP,INSIG2,ATP6V1A,SLK,CCNL2,SLC6A8,CDC73,DENR,NAMPT,NRF1,HVCN1,CWC27,LTN1,LYRM5,PTBP2,SMARCAD1,GPCPD1,ARHGEF12,PTK2,UBR4,HSD3B7,MGST1,SPOP,ARHGAP21,ALKBH3,EHMT2,SERF2,HNRNPH3,DUSP19,SOCS4,TRMT2A,APAF1 |
| 3.495e-02 | -3.35 | AAANWWTGC_UNKNOWN | MSigDB lists | AAANWWTGC_UNKNOWN | 187 | 33 | 17758 | 2279 |
FN1,ZHX3,DLGAP4,PPP2R2A,FOXP1,MBNL1,ATXN7L1,ZNF827,NEK6,CHD2,IGF2BP1,MGLL,MAML3,NRAS,SESN2,ANK2,FOXN3,PRDM16,GRHL3,POU2F1,SATB2,SOX4,RAB10,SKIL,SPAG9,SIX5,LUC7L3,HOXA3,PPP3CC,NR2F2,MID1,DDIT3,MEF2C |
| 3.495e-02 | -3.35 | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | 187 | 33 | 17758 | 2279 |
SEC24D,WDR74,RHOBTB1,SLC48A1,CAMK1,DBF4,OLA1,TIMM10,NOP56,CAD,FARSA,SUV39H2,NOP16,C16orf58,FNIP2,PRADC1,PTPRK,FADS1,PFKFB4,TIMM8B,CLYBL,PSPC1,FZD3,METTL15,CLNS1A,BSN,ZRANB3,PALB2,CUL2,EIF2S1,NR2F2,IPO4,GCSH |
| 3.501e-02 | -3.35 | IRF8 (interferon regulatory factor 8) | protein interactions | 3394 | 23 | 7 | 16036 | 2270 |
ZBTB17,COPS6,COPS4,MID1,COPS5,CDK4,TOP1 |
| 3.501e-02 | -3.35 | CPNE2 (copine II) | protein interactions | 221184 | 23 | 7 | 16036 | 2270 |
TERF2IP,SKIL,RDX,BCOR,ANXA7,COPS5,S100A16 |
| 3.501e-02 | -3.35 | CTDSP2 (CTD small phosphatase 2) | protein interactions | 10106 | 23 | 7 | 16036 | 2270 |
UBTF,ANKRD13A,MAP7D1,ZC3H3,POM121,POLR2A,SLC25A20 |
| 3.501e-02 | -3.35 | UPF3A (UPF3 regulator of nonsense transcripts homolog A (yeast)) | protein interactions | 65110 | 23 | 7 | 16036 | 2270 |
UPF2,EXOSC2,FUS,EXOSC4,IFITM2,PARN,SMG1 |
| 3.501e-02 | -3.35 | ZBTB3 (zinc finger and BTB domain containing 3) | protein interactions | 79842 | 23 | 7 | 16036 | 2270 |
SMAD3,SKIL,SUPT5H,EIF5B,PPARG,ZMYM2,PKNOX1 |
| 3.501e-02 | -3.35 | NUP88 (nucleoporin 88kDa) | protein interactions | 4927 | 23 | 7 | 16036 | 2270 |
FLNC,RNF2,NUP214,DDX19A,SET,SIRT7,CUL2 |
| 3.501e-02 | -3.35 | MRPS21 (mitochondrial ribosomal protein S21) | protein interactions | 54460 | 23 | 7 | 16036 | 2270 |
SHMT2,TRMT10B,RNF2,HNRNPR,TRA2A,ZC3H3,USP42 |
| 3.501e-02 | -3.35 | ACOT13 (acyl-CoA thioesterase 13) | protein interactions | 55856 | 23 | 7 | 16036 | 2270 |
SNU13,CMPK1,FN1,NDUFAF2,NUP214,ATIC,SBDS |
| 3.501e-02 | -3.35 | USPL1 (ubiquitin specific peptidase like 1) | protein interactions | 10208 | 23 | 7 | 16036 | 2270 |
SUMO3,SHMT2,ELL,RANGAP1,POLR2A,PGD,ANXA1 |
| 3.501e-02 | -3.35 | PDE12 (phosphodiesterase 12) | protein interactions | 201626 | 23 | 7 | 16036 | 2270 |
DCTPP1,XPNPEP1,ADSL,APEX1,PDLIM5,COPS5,UBC |
| 3.501e-02 | -3.35 | ARMT1 (acidic residue methyltransferase 1) | protein interactions | 79624 | 23 | 7 | 16036 | 2270 |
SEC31A,PPP3CC,RWDD2B,UCHL5,G6PD,ATIC,NKD2 |
| 3.511e-02 | -3.35 | nuclear matrix | cellular component | GO:0016363 | 97 | 19 | 17570 | 2233 |
NCOR2,AKAP8L,POLA1,PSPC1,SMARCAD1,ATXN1,SATB2,MEN1,ENC1,SCAF8,CAD,SNW1,ATXN7,HLCS,PHF5A,ZNF326,OGG1,HNRNPM,MYB |
| 3.520e-02 | -3.35 | BOYLAN_MULTIPLE_MYELOMA_C_D_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_UP | 128 | 24 | 17758 | 2279 |
XYLB,ARNTL2,SF3A3,AKAP12,SLC29A1,PTK2,SOX4,CHCHD6,GABPB2,TMEM206,GLS,EPRS,C6orf48,IDI1,PDLIM1,RAD51B,SLC16A1,DIRAS1,SCARB1,BPNT1,NOLC1,PABPC1,PRKACB,MTHFD1 |
| 3.526e-02 | -3.35 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | 275 | 46 | 17758 | 2279 |
TNIK,NOSTRIN,MCM6,SULT1C2,NPAS2,PSTPIP2,SLK,MFGE8,FOSL2,ST3GAL6,FOXP1,BZW2,FRRS1,IDI1,ARHGAP18,SDCBP2,WIZ,S100A14,CD44,GMDS,CDK6,PABPC1,FMNL2,SLC40A1,KRT7,STAG1,UPP1,KCNMA1,RDH10,HOMER2,COTL1,PDE2A,ENC1,KLF6,DDX60,SMPDL3B,DCBLD2,CXADR,ARL4A,HK2,SLC4A7,ABCC3,ARC,CLU,TESC,MID1 |
| 3.529e-02 | -3.34 | EPB41 (erythrocyte membrane protein band 4.1) | protein interactions | 2035 | 54 | 13 | 16036 | 2270 |
SMAD3,DYNC1H1,FN1,SF3A3,MYH9,VARS,RWDD2B,CD44,MACROD1,TPM1,CLNS1A,SPTAN1,SF3A1 |
| 3.529e-02 | -3.34 | BORCS6 (BLOC-1 related complex subunit 6) | protein interactions | 54785 | 54 | 13 | 16036 | 2270 |
RNF40,CCDC57,LUZP1,DTNBP1,LAMTOR3,ATP6V0A1,SELT,SPATS2,CEP135,TRIM37,PIBF1,BORCS5,BLOC1S2 |
| 3.530e-02 | -3.34 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing | 90 | 18 | 17775 | 2278 |
CYP24A1,RFC4,BRAF,NRAS,C1QTNF7,TRPM6,MEN1,EIF5B,NOP56,LRP1B,SIPA1L3,MED15,VPS13D,GREB1L,ZFP37,KDM5C,PDE9A,SOX6 |
| 3.538e-02 | -3.34 | myeloid cell differentiation | biological process | GO:0030099 | 198 | 35 | 16441 | 2138 |
THOC5,KMT2E,PAFAH1B1,ID2,MYH9,JMJD6,FOXP1,TGFBR2,PIP4K2A,KDM1A,PTPN2,TSPAN2,RELB,MFAP2,SOX6,PKNOX1,MYB,KAT8,PPARG,PDE2A,FLVCR1,EXOC6,BATF3,L3MBTL3,HIPK2,G6PD,RUNX1,ANXA2,BMP4,NCOR1,RBPJ,SH3PXD2A,TESC,MEF2C,KAT6A |
| 3.538e-02 | -3.34 | PCNA-Dependent Long Patch Base Excision Repair | REACTOME pathways | R-HSA-5651801 | 19 | 6 | 8202 | 1117 |
RFC4,POLB,RFC3,APEX1,POLE2,RPA1 |
| 3.538e-02 | -3.34 | dioxygenase activity | molecular function | GO:0051213 | 88 | 18 | 16491 | 2164 |
KDM6B,KDM3B,KDM5B,KDM5A,JMJD1C,MINA,PLOD1,JMJD6,P3H1,ALKBH3,KDM2A,KDM4B,ALKBH8,ALKBH1,PTGS1,KDM5C,KDM4C,TMLHE |
| 3.539e-02 | -3.34 | SDRFAMILY | prints domains | PR00080 | 40 | 8 | 4759 | 462 |
DCXR,CBR4,RDH10,HSD17B10,BDH2,HSD17B12,RDH11,HSD17B14 |
| 3.540e-02 | -3.34 | PHGDH (phosphoglycerate dehydrogenase) | protein interactions | 26227 | 99 | 21 | 16036 | 2270 |
USP7,CUL7,PSAT1,FN1,UTP14A,TRA2A,NECAP1,SON,PABPC4,UBC,ISG15,ADH5,ASNS,ADNP,CUL2,RNF2,FUS,BMI1,PABPC1,RPS6KB2,MTHFD1 |
| 3.546e-02 | -3.34 | CORO1C (coronin, actin binding protein, 1C) | protein interactions | 23603 | 65 | 15 | 16036 | 2270 |
SNU13,GARS,CUL7,SHC1,FN1,ACTG1,FMNL1,RAB7A,ACTR3,TPM4,ETF1,CYB5B,TARS,RPA1,NUDC |
| 3.546e-02 | -3.34 | MED17 (mediator complex subunit 17) | protein interactions | 9440 | 65 | 15 | 16036 | 2270 |
TRRAP,BRD4,USP49,TFIP11,MED27,MED15,MED24,SMARCA4,GPN1,MED18,MED16,BRCA1,MED20,WDR33,ZC3H13 |
| 3.547e-02 | -3.34 | ADP binding | molecular function | GO:0043531 | 30 | 8 | 16491 | 2164 |
MYO7A,MYH9,ME1,APAF1,PRPS1,LONP1,MIEF1,ATP5D |
| 3.547e-02 | -3.34 | neutral amino acid transmembrane transporter activity | molecular function | GO:0015175 | 30 | 8 | 16491 | 2164 |
SERINC5,SLC3A2,SERINC1,SLC38A5,SLC7A11,SLC38A1,SLC1A1,SLC43A1 |
| 3.550e-02 | -3.34 | ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | 351 | 57 | 17758 | 2279 |
SCAMP3,TRIP6,NF1,PAFAH1B1,KIF5A,KHDRBS1,TRAK1,VPS45,VTI1A,MAP1S,MYH9,SMG7,MON2,XPO7,OPA1,NUP160,GBF1,RPAIN,EEA1,DOPEY1,PEX7,NUP133,NCKIPSD,UPF2,TOMM34,LYST,SLC25A1,CDC37,RABEPK,USE1,ATXN1,RHOT2,SYT1,NUP214,SERGEF,NOP58,RERE,MFN2,TIMM44,PEX1,TAMM41,SMAD3,RANBP2,MYBBP1A,KPNA1,KPNA3,DNAJC1,TIMM17A,SNAP23,STX18,NCBP2,PEX13,SEPT5,NAPA,XPO6,KIF1B,SMG1 |
| 3.552e-02 | -3.34 | negative regulation of cell cycle process | biological process | GO:0010948 | 238 | 41 | 16441 | 2138 |
HMGA2,CHMP2A,THOC5,CSNK2A1,SMARCA4,GIGYF2,CDC73,PSMF1,MAD2L2,TOM1L1,ANAPC1,ANAPC11,TRIAP1,ANAPC10,MAD1L1,FBXO31,DMRT1,TERF2,PRPF19,BRD4,CRADD,FOXN3,CDK4,TEX14,PSMA1,BRCA1,MEN1,SOX4,TPRA1,TRIM37,UBE2E1,ZNF655,UBC,KLHL22,CDC16,TOM1L2,CDK9,ATM,BMP4,ANAPC4,CHMP4C |
| 3.552e-02 | -3.34 | cardiac ventricle development | biological process | GO:0003231 | 95 | 19 | 16441 | 2138 |
TNNC1,PTCD2,DLL4,LUZP1,SMAD7,ID2,RYR2,SMARCD3,SOX4,DSP,FOXC1,FKBP1A,JAG1,HIF1A,TBX3,SEMA3C,RBPJ,TPM1,MEF2C |
| 3.552e-02 | -3.34 | negative regulation of translation | biological process | GO:0017148 | 95 | 19 | 16441 | 2138 |
ATF4,AGO2,IGF2BP2,ENC1,GIGYF2,PAIP2,IGF2BP3,DDX3X,EPRS,EIF4ENIF1,IREB2,SYNCRIP,EIF2S1,IGF2BP1,CELF1,EIF2B3,SAMD4A,AGO3,TNRC6A |
| 3.552e-02 | -3.34 | NEP/NS2 Interacts with the Cellular Export Machinery | REACTOME pathways | R-HSA-168333 | 29 | 8 | 8202 | 1117 |
RANBP2,NUP133,NUP43,RAN,NUP160,NUP214,POM121,SEH1L |
| 3.552e-02 | -3.34 | Transport of Ribonucleoproteins into the Host Nucleus | REACTOME pathways | R-HSA-168271 | 29 | 8 | 8202 | 1117 |
RANBP2,KPNA1,NUP133,NUP43,NUP160,NUP214,POM121,SEH1L |
| 3.552e-02 | -3.34 | Extension of Telomeres | REACTOME pathways | R-HSA-180786 | 29 | 8 | 8202 | 1117 |
RFC4,RFC3,APEX1,POLE2,PRIM2,POLA1,DKC1,RPA1 |
| 3.563e-02 | -3.33 | collagen binding | molecular function | GO:0005518 | 64 | 14 | 16491 | 2164 |
SMAD3,RELL2,P3H1,FN1,ITGA2,C1QTNF1,DDR2,TNXB,SMAD7,ADAM9,PCOLCE2,CD44,SERPINH1,HSD17B12 |
| 3.564e-02 | -3.33 | regulation of blood vessel endothelial cell migration | biological process | GO:0043535 | 47 | 11 | 16441 | 2138 |
DLL4,AMOTL1,MAP2K5,MMRN2,FGF2,NF1,KLF4,PRKCA,HRG,AMOT,ANGPT2 |
| 3.564e-02 | -3.33 | face development | biological process | GO:0060324 | 47 | 11 | 16441 | 2138 |
CHD7,MSX1,ARID5B,CSRNP1,ANKRD11,MYH3,TGFB2,TCF7L2,DKK1,KAT6A,SKI |
| 3.564e-02 | -3.33 | negative regulation of DNA binding | biological process | GO:0043392 | 47 | 11 | 16441 | 2138 |
HMGA2,ZNF675,MSX2,ID1,MSX1,ID2,ZFP90,RSF1,MAD2L2,KDM1A,DDIT3 |
| 3.564e-02 | -3.33 | human chr16q22.1 | chromosome location | human chr16q22.1 | 100 | 16 | 26250 | 2590 |
DDX28,TANGO6,DDX19A,NOL3,CYB5B,SLC9A5,VAC14,ACD,HAS3,E2F4,RLTPR,ZFP90,PLEKHG4,ATP6V0D1,UTP4,TERF2 |
| 3.569e-02 | -3.33 | PPA1 (pyrophosphatase (inorganic) 1) | protein interactions | 5464 | 33 | 9 | 16036 | 2270 |
DDAH2,NAV1,FN1,ITPA,TLE3,RDX,C11orf54,CLNS1A,PABPC4 |
| 3.569e-02 | -3.33 | MSI2 (musashi RNA binding protein 2) | protein interactions | 124540 | 33 | 9 | 16036 | 2270 |
FKBP1A,RBFOX2,RAB7A,H2AFX,RNF2,BMI1,PABPC1,PABPC4,RPA1 |
| 3.569e-02 | -3.33 | TRIM9 (tripartite motif containing 9) | protein interactions | 114088 | 33 | 9 | 16036 | 2270 |
EXOC1,PCGF3,EVL,SPG21,CUL2,DTNBP1,SNAP25,CWF19L2,GFM2 |
| 3.569e-02 | -3.33 | HIRIP3 (HIRA interacting protein 3) | protein interactions | 8479 | 33 | 9 | 16036 | 2270 |
CARS,GARS,GART,SET,CSNK2A1,XPO7,TROVE2,PRMT3,SRPK2 |
| 3.569e-02 | -3.33 | PPP4R3A (protein phosphatase 4, regulatory subunit 3A) | protein interactions | 55671 | 33 | 9 | 16036 | 2270 |
FKBP1A,ALKBH3,EHMT2,HNRNPR,EHMT1,BRCC3,IGBP1,POLR2A,SF3A1 |
| 3.569e-02 | -3.33 | RFC3 (replication factor C subunit 3) | protein interactions | 5983 | 33 | 9 | 16036 | 2270 |
RFC4,BRD4,MYC,SMARCAD1,FAN1,PURB,USP20,UBC,RPA1 |
| 3.569e-02 | -3.33 | FIP1L1 (factor interacting with PAPOLA and CPSF1) | protein interactions | 81608 | 33 | 9 | 16036 | 2270 |
CUL7,COPS5,LIG4,CSNK2A1,RNF2,WDR33,CPSF3,SRRM2,CLK2 |
| 3.569e-02 | -3.33 | S100A16 (S100 calcium binding protein A16) | protein interactions | 140576 | 33 | 9 | 16036 | 2270 |
SUCLG1,UCHL5,UBXN1,VAPB,SUCLG2,RTN4,TMEM177,S100A14,MPST |
| 3.572e-02 | -3.33 | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | 194 | 34 | 17758 | 2279 |
SUCLG1,DYM,WDR13,IQGAP2,ANXA5,CD44,FBL,ITGAX,CDC37,KLRD1,RREB1,APEX1,PDK1,ITPA,LDHA,CUX1,PACS1,CCNDBP1,IMPDH2,IL6R,RABAC1,C8orf33,KLF6,MAT2A,RERE,ANXA1,PWP1,YIF1A,COPS5,NSMCE1,ARL6IP5,ORC5,EIF2S1,GALNT10 |
| 3.572e-02 | -3.33 | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDM_DN | 194 | 34 | 17758 | 2279 |
PDE4B,ZFP36L1,RNF141,UBR1,PVRL3,XRCC2,IPP,CTR9,POLR1B,FBXO31,ERRFI1,AGL,ANGPT2,TOP1,DDHD1,EIF4E3,COL17A1,ARID5B,ATF7IP2,TEX14,PRDM1,ODC1,DSP,LSG1,NOP58,UBC,GADD45A,LSM14A,CEBPZ,FTSJ1,SVIL,PREPL,DOCK6,TMEM33 |
| 3.572e-02 | -3.33 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 194 | 34 | 17758 | 2279 |
MCM10,ATP6V1A,CAMK1,KLHL18,SMARCA4,SPATS2,PHGDH,UBR5,BIRC2,LPIN1,DDIT4,DCTPP1,SH2B3,BANF1,ANP32B,ALDH18A1,TRIP13,HN1,TERF2,MYB,SCAF11,CDK4,HSPA5,ATOX1,KIF15,MARCH6,BRCA2,MTHFD2,RBBP8,TRMT5,ZNF160,H2AFX,XPNPEP1,AP2S1 |
| 3.572e-02 | -3.33 | GSE27786_LIN_NEG_VS_NKCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NKCELL_UP | 194 | 34 | 17758 | 2279 |
PCNT,SUCLG1,LRRC28,RHOBTB1,MRI1,DDX19A,TNXB,NKD2,AP1B1,FRRS1,NOP56,FARSA,NOP16,COPS3,ANP32B,TIMM8B,GARS,TRIM13,CLYBL,NOL8,ADSL,ANGPTL4,CCDC150,CLNS1A,PES1,PWP1,ARHGAP21,INTS9,H2AFX,SETD6,TXN2,IPO4,HS2ST1,MORC2 |
| 3.572e-02 | -3.33 | GSE22886_NAIVE_BCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_DN | 194 | 34 | 17758 | 2279 |
SEPHS2,NCOR2,FEZ2,ANKRD17,ITFG1,MAP1S,RTN4,CCDC47,SLC25A44,SYNJ1,ABHD6,MAN1A1,SLC7A11,DNAJB6,HN1,TOP1,PEA15,RREB1,LGALS1,TPM4,CUX1,ATXN1,MAP7D1,NEU1,TPK1,PGD,GLS,RARS,TMCO1,MTHFD2,MPV17,TNFRSF1A,NRP1,NAPA |
| 3.572e-02 | -3.33 | GSE7852_TREG_VS_TCONV_FAT_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_DN | 194 | 34 | 17758 | 2279 |
ARHGAP26,ST6GAL1,RPS29,LETMD1,JMJD6,ST3GAL6,INPP1,HSPA1A,PAG1,CD96,CNST,ENTPD5,ASAP1,MCM5,CPNE7,KIAA0922,LYST,TRIM13,KIAA1143,TSPYL4,HAUS6,BMS1,MCM2,ENC1,PHF6,RERE,HSPA1B,EXOC6,BTBD11,TRIB3,C20orf196,NFRKB,GALNT10,TESC |
| 3.573e-02 | -3.33 | MODULE_480 | MSigDB lists | MODULE_480 | 90 | 18 | 17758 | 2279 |
MIF4GD,FERMT2,FOSL2,ENOX1,SYT1,FLVCR1,CHCHD6,BMP6,FAM49A,HSPA1A,MAD2L2,HSPA1B,ABCA7,YTHDF2,SRPRB,SIL1,ZEB1,SPOCK2 |
| 3.573e-02 | -3.33 | G-protein_beta_WD-40_rep | interpro domains | IPR020472 | 84 | 17 | 18293 | 2341 |
GNB3,WDR61,PAFAH1B1,WDR18,PLRG1,WDR37,NLE1,PWP1,GEMIN5,PEX7,WDR5B,PAK1IP1,PRPF4,APAF1,TBL1X,SEH1L,PRPF19 |
| 3.574e-02 | -3.33 | Processing of DNA double-strand break ends | REACTOME pathways | R-HSA-5693607 | 97 | 20 | 8202 | 1117 |
HERC2,RFC4,RFC3,SIRT6,TOP3A,BRCA1,HIST1H2BL,HIST1H4J,RMI1,UBC,RPA1,EXO1,RBBP8,BRE,TP53BP1,H2AFX,TIMELESS,ATRIP,ATM,BRCC3 |
| 3.577e-02 | -3.33 | H2AFX (H2A histone family, member X) | protein interactions | 3014 | 213 | 40 | 16036 | 2270 |
PRDX6,XPC,PRKCSH,SIRT7,HSD17B10,FANCD2,PLOD1,CSNK2A1,SMARCA4,FOXO3,HSPA1A,P3H1,EIF2S2,SURF2,ANXA5,HIBCH,RNF2,SSBP1,PABPC1,TERF2,MSI2,KAT8,EYA3,HSPA5,BRCA1,SUPT5H,POLR2A,UBC,BRCA2,SYNCRIP,TP53BP1,TRAP1,HNRNPR,HNRNPH3,H2AFX,ATM,ANXA2,CLU,BMI1,STK4 |
| 3.583e-02 | -3.33 | regulation of transcription from RNA polymerase I promoter | biological process | GO:0006356 | 25 | 7 | 16441 | 2138 |
SMARCA4,UBTF,HEATR1,ATF4,DHX33,UTP15,SMARCB1 |
| 3.583e-02 | -3.33 | maturation of 5.8S rRNA | biological process | GO:0000460 | 25 | 7 | 16441 | 2138 |
PES1,EXOSC2,EXOSC4,ERI3,SKIV2L2,ERI1,FTSJ3 |
| 3.583e-02 | -3.33 | mitochondrial genome maintenance | biological process | GO:0000002 | 25 | 7 | 16441 | 2138 |
SESN2,OPA1,POLG2,DNAJA3,C10orf2,LONP1,MPV17 |
| 3.583e-02 | -3.33 | nuclear-transcribed mRNA poly(A) tail shortening | biological process | GO:0000289 | 25 | 7 | 16441 | 2138 |
CNOT6,MLH1,CNOT4,TNKS1BP1,PARN,PABPC1,EIF4A2 |
| 3.583e-02 | -3.33 | blood vessel endothelial cell migration | biological process | GO:0043534 | 25 | 7 | 16441 | 2138 |
EFNB2,MYH9,ID1,NRP1,FGF2,AMOT,LEMD3 |
| 3.583e-02 | -3.33 | porphyrin-containing compound biosynthetic process | biological process | GO:0006779 | 25 | 7 | 16441 | 2138 |
HMBS,ALAD,FXN,COX10,TMEM14C,CPOX,UROD |
| 3.587e-02 | -3.33 | CHMP5 (charged multivesicular body protein 5) | protein interactions | 51510 | 28 | 8 | 16036 | 2270 |
PXN,STAMBP,VTA1,SMARCA4,ZNF142,ZNF91,ISG15,SNCA |
| 3.587e-02 | -3.33 | MRPS14 (mitochondrial ribosomal protein S14) | protein interactions | 63931 | 28 | 8 | 16036 | 2270 |
DDX56,TRA2A,USP42,MPV17,MRPS10,TRMT10B,ZC3H3,MRPS11 |
| 3.587e-02 | -3.33 | WAPL (WAPL cohesin release factor) | protein interactions | 23063 | 28 | 8 | 16036 | 2270 |
STAG1,SIRT6,NSMCE2,PDS5B,USP10,BRCA1,USP15,RPA1 |
| 3.587e-02 | -3.33 | CD55 (CD55 molecule, decay accelerating factor for complement (Cromer blood group)) | protein interactions | 1604 | 28 | 8 | 16036 | 2270 |
INF2,S100A10,SLC2A1,MPV17,ADGRE5,PTRH2,NDUFS7,TIMM50 |
| 3.587e-02 | -3.33 | EEA1 (early endosome antigen 1) | protein interactions | 8411 | 28 | 8 | 16036 | 2270 |
TNK2,NSF,RNF2,MARS,PXK,BMI1,EEA1,RABEP1 |
| 3.611e-02 | -3.32 | Nucleotide-bd_a/b_plait | interpro domains | IPR012677 | 242 | 41 | 18293 | 2341 |
NIFK,RBM33,RBFOX2,PPARGC1B,IGF2BP2,PABPC1L,RBM19,ENOX1,SYNJ1,PARN,SAFB2,HNRNPA3,SCAF8,HNRNPLL,PABPC4,IGF2BP3,RBM20,SRSF2,CELF1,IGF2BP1,SYNJ2,CNOT4,PABPC1,HNRNPM,MSI2,PTBP2,SETD1B,PSPC1,TRA2A,NOL8,RBM28,SYNCRIP,HNRNPR,LEMD3,SPEN,HNRNPH3,TRMT2A,NCBP2,RBM26,FUS,TNRC6A |
| 3.611e-02 | -3.32 | PRPF31 (pre-mRNA processing factor 31) | protein interactions | 26121 | 105 | 22 | 16036 | 2270 |
SART1,SNU13,CCDC57,PRPF31,ZNF587,TFIP11,C1QTNF1,SF3A3,CHAF1A,PHC2,KPNA1,CTNNBL1,PHF5A,COPS5,UPF2,PRPF4,FBL,MIPOL1,PNMA1,AGO3,SF3A1,USP15 |
| 3.611e-02 | -3.32 | NUDT21 (nudix hydrolase 21) | protein interactions | 11051 | 105 | 22 | 16036 | 2270 |
DBN1,CUL7,FN1,SKIV2L2,TRA2A,JMJD1C,ATXN1,VIM,SIRT2,CEP126,PSMF1,NEDD4,RPA1,PYCR1,FLAD1,SHC1,EEFSEC,RNF2,FUS,XRCC4,CARM1,SRPK2 |
| 3.612e-02 | -3.32 | establishment of tissue polarity | biological process | GO:0007164 | 15 | 5 | 16441 | 2138 |
CELSR1,PAFAH1B1,FZD3,RPGRIP1L,GRHL3 |
| 3.612e-02 | -3.32 | negative regulation of histone methylation | biological process | GO:0031061 | 15 | 5 | 16441 | 2138 |
BCOR,BRCA1,SUPT6H,KDM1A,SMARCB1 |
| 3.612e-02 | -3.32 | specification of organ identity | biological process | GO:0010092 | 15 | 5 | 16441 | 2138 |
SMARCD3,RBPJ,BMP4,PAX2,MEF2C |
| 3.612e-02 | -3.32 | establishment of planar polarity | biological process | GO:0001736 | 15 | 5 | 16441 | 2138 |
CELSR1,PAFAH1B1,FZD3,RPGRIP1L,GRHL3 |
| 3.612e-02 | -3.32 | cellular response to antibiotic | biological process | GO:0071236 | 15 | 5 | 16441 | 2138 |
HMBS,EGR1,HSPA5,RAB10,MEF2C |
| 3.612e-02 | -3.32 | hyaluronan catabolic process | biological process | GO:0030214 | 15 | 5 | 16441 | 2138 |
HYAL1,HYAL3,CD44,FGF2,CEMIP |
| 3.612e-02 | -3.32 | negative regulation of anoikis | biological process | GO:2000811 | 15 | 5 | 16441 | 2138 |
PTRH2,MCL1,PTK2,CAV1,PDK4 |
| 3.612e-02 | -3.32 | inner cell mass cell proliferation | biological process | GO:0001833 | 15 | 5 | 16441 | 2138 |
BRCA2,BRD4,PALB2,SBDS,PRPF19 |
| 3.612e-02 | -3.32 | regulation of translational fidelity | biological process | GO:0006450 | 15 | 5 | 16441 | 2138 |
DTD1,VARS,GATC,LARS2,AARS |
| 3.613e-02 | -3.32 | Glutamate Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-210500 | 24 | 7 | 8202 | 1117 |
GLS,SNAP25,SYT1,STX1A,ARL6IP5,SLC1A1,SLC38A2 |
| 3.613e-02 | -3.32 | Pyrimidine metabolism | REACTOME pathways | R-HSA-73848 | 24 | 7 | 8202 | 1117 |
CAD,UMPS,NT5C,NT5C3A,NT5M,UPP1,NT5E |
| 3.614e-02 | -3.32 | IARS (isoleucyl-tRNA synthetase) | protein interactions | 3376 | 82 | 18 | 16036 | 2270 |
GARS,CUL7,CUL4A,FN1,NARS,MARS,AARS,UBC,CIAPIN1,SNCA,IGF2BP3,CAD,EPRS,RARS,ASNS,SHC1,SYNCRIP,COPS5 |
| 3.615e-02 | -3.32 | bone-ilium-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-ilium-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 84 | 17 | 17775 | 2278 |
ABCA3,EVL,BRAF,KMT2D,OPA1,SRA1,PDE3A,DHX57,MGA,GZF1,TOE1,GRIN2C,CTR9,TIMELESS,MDN1,CEP135,ZNF646 |
| 3.617e-02 | -3.32 | Type 2 diabetes(PMID:17463249) | GWAS genes | Type 2 diabetes(PMID:17463249) | 8 | 4 | 2389 | 419 |
CDKAL1,IGF2BP2,PPARG,TCF7L2 |
| 3.622e-02 | -3.32 | ITGA4 (integrin alpha 4) | protein interactions | 3676 | 511 | 87 | 16036 | 2270 |
SRM,CHMP2A,PRDX6,ACTG1,SLC2A1,NAT10,MYH9,RSL1D1,PPIL1,AARS,HSPA1A,HNRNPA3,UBL5,PABPC4,FLNB,CAD,DECR1,RPS16,ASNS,UBAP2L,RAN,VCL,YARS,LONP1,PTPRK,SNU13,LGALS1,PCMT1,VIM,HIST1H2BL,MCM2,NUP214,UBR4,RAB10,PYCR1,ARPC3,DDX3X,HNRNPR,ACP1,FUS,HEATR1,ANXA2,AP2S1,MCM6,FN1,ANKRD17,HSD17B10,APRT,VARS,IGF2BP2,CSNK1A1,MBNL1,MCM5,SEC24C,HIST2H3D,ANP32B,IGF2BP1,FBL,TOMM34,PABPC1,LYPLA2,HNRNPM,NUDC,TOP1,HBG2,PXN,XPO5,RAP1B,LDHA,PSMA1,MARS,HIST1H4J,PTK2,TARS,UBC,HSPA1B,ANXA1,DYNC1H1,SEC31A,EPRS,SYNCRIP,RPL28,VCAN,HNRNPH3,HK2,EIF2S1,NAPA |
| 3.624e-02 | -3.32 | cervix-carcinoma | COSMIC cancer mutations | cervix-carcinoma | 42 | 10 | 17775 | 2278 |
ABL1,SRSF2,BRAF,NRAS,NF1,ATM,RUNX1,MET,FGFR1,SMARCB1 |
| 3.628e-02 | -3.32 | Dynein_heavy | pfam domains | PF03028 | 15 | 5 | 16629 | 2165 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 3.628e-02 | -3.32 | MT | pfam domains | PF12777 | 15 | 5 | 16629 | 2165 |
DYNC1H1,DNAH2,DYNC2H1,DNAH1,DNAH14 |
| 3.643e-02 | -3.31 | embryonic organ development | biological process | GO:0048568 | 423 | 68 | 16441 | 2138 |
THOC5,BIRC6,MKS1,MYO7A,PBX1,SLC39A1,CHD7,DNAJB6,MMP14,VPS52,ZEB1,HYAL1,CCDC40,KMT2A,SOBP,WDPCP,GRHL3,SATB2,MTHFD1L,FLVCR1,FGFR1,SMAD3,EPN2,INSIG1,HIPK2,ARL13B,MKL2,HOXA3,DLX2,RUNX1,NRP1,MEF2C,CHST11,INSIG2,IFT57,CELSR1,PAX2,ID2,ZFP36L1,TGFB2,TGFBR2,SH2B3,CEP290,NDRG4,WNT16,MFAP2,MTHFD1,MYB,TSHZ1,FGF9,MSX1,RDH10,SETD2,FZD3,RYR2,PRDM1,ARID1A,FOXC1,TCF7L2,PALB2,HIF1A,TBX3,BMP4,RBPJ,NR2F2,MMP16,KAT6A,STK4 |
| 3.655e-02 | -3.31 | RUAN_RESPONSE_TO_TNF_TROGLITAZONE_DN | MSigDB lists | RUAN_RESPONSE_TO_TNF_TROGLITAZONE_DN | 42 | 10 | 17758 | 2279 |
AOC3,ALAD,PPARG,PEMT,HIPK2,CFD,IDH3G,HK2,GPAM,NRIP1 |
| 3.656e-02 | -3.31 | V$POU6F1_01 | MSigDB lists | V$POU6F1_01 | 228 | 39 | 17758 | 2279 |
COMMD10,RHOBTB1,RBFOX2,GTF2IRD1,ID2,RTN4,FOXP1,MBNL1,PCDH7,ZNF827,TSPAN2,NEK6,PRICKLE2,JOSD1,CHD2,ETV1,SOBP,WARS2,MPP6,FAM172A,NR6A1,FOXN3,KCNMA1,CUX1,POU2F1,SOX4,NR2F1,RERE,STOML2,BAZ1A,SKIL,CAMK2D,GRIK4,NSD1,SPAG9,TRAF3,NFRKB,USP11,IPO4 |
| 3.660e-02 | -3.31 | DNA replication initiation | REACTOME pathways | R-HSA-68952 | 6 | 3 | 8202 | 1117 |
POLE2,PRIM2,POLA1 |
| 3.660e-02 | -3.31 | Telomere C-strand synthesis initiation | REACTOME pathways | R-HSA-174430 | 6 | 3 | 8202 | 1117 |
POLE2,PRIM2,POLA1 |
| 3.660e-02 | -3.31 | Synthesis of wybutosine at G37 of tRNA(Phe) | REACTOME pathways | R-HSA-6782861 | 6 | 3 | 8202 | 1117 |
TRMT5,TRMT12,TYW1 |
| 3.660e-02 | -3.31 | DNA Damage Reversal | REACTOME pathways | R-HSA-73942 | 6 | 3 | 8202 | 1117 |
ASCC3,ASCC1,ALKBH3 |
| 3.672e-02 | -3.30 | artery morphogenesis | biological process | GO:0048844 | 53 | 12 | 16441 | 2138 |
CHD7,DLL4,JAG1,NF1,SMAD7,PRDM1,BMP4,RBPJ,SOX4,NRP1,FOXC1,KAT6A |
| 3.674e-02 | -3.30 | HDAC6 (histone deacetylase 6) | protein interactions | 10013 | 195 | 37 | 16036 | 2270 |
USP7,CYLD,DDX19A,SMAD7,SIRT2,BCOR,PRKCA,SEC16A,EEA1,GBF1,KDM1A,CAD,DNAJB6,RELB,SHMT2,POLR1B,SRRM2,PPA1,TIMM50,SF3A1,PXN,TUBA1A,DDX41,HSPA5,CAV1,UBE2E1,ISG15,UBC,DYNC1H1,KPNA1,SMARCC1,HIF1A,FAT1,ATM,FNTB,MAPT,DDIT3 |
| 3.674e-02 | -3.30 | NOTCH1 (notch 1) | protein interactions | 4851 | 195 | 37 | 16036 | 2270 |
TCF12,USP7,SART1,DLL4,RFX1,PPP2R2A,SMARCA4,HLTF,KDM1A,RING1,RNF40,ANAPC1,SNW1,JAG1,MCM5,NBEA,WIZ,RNF2,MAML3,PRPF19,GATAD2B,RFC4,TRAPPC9,ZBED4,XPO5,ARIH2,SMAD3,ASCC3,SMARCC1,RLTPR,RUNX1,MDN1,RBPJ,USP11,MEF2C,USP15,LRCH1 |
| 3.676e-02 | -3.30 | human chr9p22.1 | chromosome location | human chr9p22.1 | 8 | 3 | 26250 | 2590 |
PLIN2,HAUS6,RRAGA |
| 3.676e-02 | -3.30 | human chr14q21 | chromosome location | human chr14q21 | 8 | 3 | 26250 | 2590 |
MGAT2,DDHD1,GNG2 |
| 3.678e-02 | -3.30 | establishment of protein localization to plasma membrane | biological process | GO:0090002 | 83 | 17 | 16441 | 2138 |
JUP,ANK2,NKD2,PACS1,GAS6,RAB10,S100A10,NSF,IKBKB,TNFRSF1A,RDX,NFASC,ANXA2,TSPAN14,LAMA5,TSPAN5,TESC |
| 3.692e-02 | -3.30 | RB1 (retinoblastoma 1) | protein interactions | 5925 | 232 | 43 | 16036 | 2270 |
USP7,HMGA2,TAF1,PAX2,TCF3,ID2,SMARCA4,PLA2G12A,PELP1,KDM1A,RING1,SMARCB1,SKI,ABL1,RNF40,SNW1,KDM2A,MYC,GTF2H1,CDK6,CASP10,TMPO,KDM5B,PPARG,POLA1,CDK4,KDM5A,CUX1,BRCA1,ENC1,UBR4,DYRK1B,SKIL,VDR,UBTF,CDC16,RBBP8,ARID3B,TRAP1,HIF1A,CDK9,E2F4,BAG1 |
| 3.693e-02 | -3.30 | rRNA transcription | biological process | GO:0009303 | 20 | 6 | 16441 | 2138 |
NIFK,GTF3C3,POLR1B,POLR1E,NPM3,SIRT7 |
| 3.693e-02 | -3.30 | mitochondrial fission | biological process | GO:0000266 | 20 | 6 | 16441 | 2138 |
FIS1,GDAP1,OPA1,COX10,ATG3,MIEF1 |
| 3.693e-02 | -3.30 | mitochondrion morphogenesis | biological process | GO:0070584 | 20 | 6 | 16441 | 2138 |
PID1,NUBPL,FIS1,SSBP1,POLG2,COL4A3BP |
| 3.693e-02 | -3.30 | regulation of anoikis | biological process | GO:2000209 | 20 | 6 | 16441 | 2138 |
PTRH2,MCL1,PTK2,MYBBP1A,CAV1,PDK4 |
| 3.693e-02 | -3.30 | L-glutamate transport | biological process | GO:0015813 | 20 | 6 | 16441 | 2138 |
SLC25A12,SLC7A11,SLC1A1,ARL6IP5,NTSR1,PRAF2 |
| 3.693e-02 | -3.30 | positive regulation of cardiac muscle tissue growth | biological process | GO:0055023 | 20 | 6 | 16441 | 2138 |
FGF9,RBPJ,GATA6,FGF2,FGFR1,MEF2C |
| 3.693e-02 | -3.30 | regulation of vesicle fusion | biological process | GO:0031338 | 20 | 6 | 16441 | 2138 |
VPS18,CORO1A,ANXA2,STXBP6,C2CD5,ANXA1 |
| 3.704e-02 | -3.30 | LNS2 | smart domains | SM00775 | 6 | 3 | 9131 | 1249 |
PITPNM1,LPIN2,LPIN1 |
| 3.704e-02 | -3.30 | tRNA_SAD | smart domains | SM00863 | 6 | 3 | 9131 | 1249 |
AARS,TARS,AARS2 |
| 3.704e-02 | -3.30 | DUSP | smart domains | SM00695 | 6 | 3 | 9131 | 1249 |
USP20,USP11,USP15 |
| 3.710e-02 | -3.29 | V$CART1_01 | MSigDB lists | V$CART1_01 | 208 | 36 | 17758 | 2279 |
PRPF38B,DLL4,MAP2K5,MKS1,RCHY1,PBX1,RCAN1,UBR5,POGZ,MTUS1,IKZF5,CEP290,PVRL3,ZNF148,CHD2,SLC16A9,YARS,OGG1,NRAS,WARS2,WDPCP,TCEB3,MSRB3,POU2F1,PRDM1,SOX4,MBNL2,HSD3B7,STOML2,KIAA0355,HOXA3,TMEM117,TRAF3,MID1,TNRC6A,MEF2C |
| 3.710e-02 | -3.29 | V$LEF1_Q2 | MSigDB lists | V$LEF1_Q2 | 208 | 36 | 17758 | 2279 |
CGN,SCAMP3,DDR2,SMG7,RSF1,TIMM10,GBF1,AMPD3,NAV1,TSPAN2,CACNB2,FGGY,UBAP2L,SLC16A9,AHCYL1,YARS,SOX6,ACSL5,NARS2,AP4B1,FRA10AC1,ARID1A,C10orf76,TCF7L2,NCDN,RERE,MFN2,DKK1,AHNAK,ATAD5,GADD45A,HNRNPR,BMI1,SPOCK2,RAB30,ATXN7L2 |
| 3.713e-02 | -3.29 | VAPB (VAMP (vesicle-associated membrane protein)-associated protein B and C) | protein interactions | 9217 | 117 | 24 | 16036 | 2270 |
CTU2,OSBP2,RB1CC1,OSBPL9,ARHGEF12,SSR4,LSG1,PITPNM1,UBC,S100A16,OSBPL1A,TTC1,INSIG1,STX1A,RASSF3,CEBPZ,USP20,VAPB,RMDN3,VCL,AKAP11,MPST,PRKACB,STK4 |
| 3.716e-02 | -3.29 | SRC (SRC proto-oncogene, non-receptor tyrosine kinase) | protein interactions | 6714 | 326 | 58 | 16036 | 2270 |
EFNB2,CDCP1,JUP,TRIP6,FOXO1,KHDRBS1,PTPRA,PPARGC1B,MAPK8IP3,DDR2,CSNK2A1,CCNL2,PRKCA,PELP1,NEDD4,SMARCB1,TOM1L1,PTPN2,PRKCH,PRKCE,ABL1,SHC1,ANXA7,ASAP1,IKBKB,ANKRD11,ARHGAP1,FHIT,MET,CD44,VCL,CAV2,CDC37,SPTAN1,RPS6KB2,TNK2,ARHGAP17,PXN,EVL,SKAP2,DLG4,CAV1,ARHGAP32,IL6R,PTK2,FGFR1,POLR2A,SNCA,ANXA1,VDR,HIF1A,E2F4,TNFRSF1A,RPS6KB1,TRAF3,ANXA2,SH3PXD2A,MAPT |
| 3.721e-02 | -3.29 | - | gene3d domains | 1.25.10.10 | 210 | 39 | 9988 | 1398 |
RTTN,JUP,NF1,PIK3R4,MON2,AP1B1,TTI1,ARID1B,TMCO6,CTNNBL1,ARMC6,INTS7,ARMC5,PDS5B,TNPO3,IPO11,SPAG6,RANBP6,IFRD1,C1orf228,WDFY3,TANGO6,AP4B1,XPO5,PACRGL,RAP1GDS1,SYMPK,ARMC3,VAC14,PUM3,ARMC4,TRRAP,KPNA1,KPNA3,AGTPBP1,SIL1,HEATR1,XPO6,IPO4 |
| 3.722e-02 | -3.29 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | 168 | 30 | 17758 | 2279 |
ACSL5,INSIG2,PDK1,GPHN,CCDC53,RHOBTB1,SPRYD7,PDK4,CORIN,PTPRG,ABHD6,FAM8A1,GNAI1,IRS1,NUBPL,CTNNBL1,HSDL2,DCXR,TBX3,DNAJC12,DPP4,SLC16A1,GPAM,BMP4,TBCK,TSPAN5,CDK6,SLC16A10,RBP1,MTHFD1 |
| 3.723e-02 | -3.29 | multi-organism transport | biological process | GO:0044766 | 36 | 9 | 16441 | 2138 |
THOC5,VPS37A,KPNA1,KPNA3,VPS37B,CAV1,RAN,CAV2,UBC |
| 3.723e-02 | -3.29 | regulation of gluconeogenesis | biological process | GO:0006111 | 36 | 9 | 16441 | 2138 |
PTPN2,RANBP2,SESN2,FOXO1,NLN,SUPT20H,SOGA1,TCF7L2,CLK2 |
| 3.723e-02 | -3.29 | oocyte differentiation | biological process | GO:0009994 | 36 | 9 | 16441 | 2138 |
BRCA2,KMT2D,ATM,KIAA0196,PABPC1L,DMRT1,FOXO3,PDE3A,TRIP13 |
| 3.723e-02 | -3.29 | DNA damage response, detection of DNA damage | biological process | GO:0042769 | 36 | 9 | 16441 | 2138 |
HMGA2,RFC4,CUL4A,RFC3,RAD18,SOX4,UBC,RPA1,MRPS11 |
| 3.723e-02 | -3.29 | multi-organism localization | biological process | GO:1902579 | 36 | 9 | 16441 | 2138 |
THOC5,VPS37A,KPNA1,KPNA3,VPS37B,CAV1,RAN,CAV2,UBC |
| 3.723e-02 | -3.29 | negative regulation of endothelial cell migration | biological process | GO:0010596 | 36 | 9 | 16441 | 2138 |
DLL4,MAP2K5,MMRN2,FGF2,PTPRM,KLF4,NR2F2,HRG,ANGPT2 |
| 3.731e-02 | -3.29 | post-translational protein modification | biological process | GO:0043687 | 382 | 62 | 16441 | 2138 |
HERC2,PIGM,MPI,ESCO1,PIGN,DPH1,SEC24D,PRKCSH,XPC,B4GALT5,ST6GAL1,ALG8,PIGH,DPM3,GAS6,NUP43,ST3GAL6,ARSJ,NUP160,SEC16A,RHBDD1,RING1,POM121,MAN1A1,PHC2,NUP133,CNIH3,SEC24C,PIGG,DPH6,RNF2,SEH1L,SEC24A,TRAPPC9,ALG6,STAG1,ATG12,SCMH1,SUMO3,ST6GALNAC3,BRCA1,TRAPPC6B,EDEM2,NUP214,ST3GAL5,NEU1,RPA1,MGAT2,SEC31A,RANBP2,ALG5,NSF,NSMCE1,AGTPBP1,NSMCE2,SRD5A3,ATG7,CTAGE5,GALNT10,XRCC4,BMI1,NAPA |
| 3.731e-02 | -3.29 | GNF2_PA2G4 | MSigDB lists | GNF2_PA2G4 | 78 | 16 | 17758 | 2279 |
CDK4,OLA1,MLH1,DKC1,TARS,CLNS1A,CAD,MTHFD2,NOP16,MCM5,FDPS,BANF1,EIF2S1,RAN,SSBP1,SERBP1 |
| 3.732e-02 | -3.29 | mitochondrial membrane organization | biological process | GO:0007006 | 59 | 13 | 16441 | 2138 |
LETM1,PMAIP1,HK2,OPA1,NOL3,TIMM10,RHOT2,CHCHD6,C19orf70,TIMM50,BLOC1S2,MFN2,SNCA |
| 3.734e-02 | -3.29 | INTS6 (integrator complex subunit 6) | protein interactions | 26512 | 49 | 12 | 16036 | 2270 |
DDX24,INTS7,INTS5,ASUN,INTS9,INTS12,SHMT2,BMI1,C7orf26,POLR2A,CPSF3L,RPA1 |
| 3.734e-02 | -3.29 | STOM (stomatin) | protein interactions | 2040 | 49 | 12 | 16036 | 2270 |
EPRS,FN1,TRIP6,ATP6V1A,FMNL1,ATIC,CUL2,SLC2A1,SVIL,UBC,SBDS,HNRNPM |
| 3.735e-02 | -3.29 | Chromo/shadow_dom | interpro domains | IPR000953 | 31 | 8 | 18293 | 2341 |
CHD7,KAT8,CHD9,SMARCC1,SUV39H2,CHD3,CHD2,CHD5 |
| 3.735e-02 | -3.29 | GNL3 (guanine nucleotide binding protein-like 3 (nucleolar)) | protein interactions | 26354 | 71 | 16 | 16036 | 2270 |
BCCIP,SNU13,NIFK,CUL7,DDX24,SIRT7,DKC1,NOP58,PUM3,NOP56,DOT1L,PES1,COPS5,RNF2,FBL,FTSJ3 |
| 3.735e-02 | -3.29 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDM_UP | 188 | 33 | 17758 | 2279 |
FEZ2,PPARGC1B,SIRT7,DBF4,NECAP1,FAM8A1,MGA,FKBP1A,ANAPC1,NPRL2,GATC,PHF5A,ATG3,UCHL5,MAP3K14,CASP8AP2,RREB1,POLK,ANKMY2,POLR3A,USP36,MGAT2,SERF2,CDK9,SPEN,ACOX1,DNAJA3,INTS5,ARNTL,ORC5,BRCC3,ZC3H8,SYNPO |
| 3.735e-02 | -3.29 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_UP | 188 | 33 | 17758 | 2279 |
ADAM19,C9orf78,MCM10,PRDX6,XPC,VPS45,CHCHD10,GBF1,NOP56,ADH5,TBC1D22A,DCTN4,ARHGAP1,ANP32B,POLE3,KIAA0922,ALDH18A1,TIMM50,GNL3,TMEM126A,ELP3,PSMG1,MEF2D,IMPDH2,CLNS1A,HERPUD1,PAF1,LSS,CTAGE5,GPAM,ZMAT3,TMEM141,NR2C2AP |
| 3.735e-02 | -3.29 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | 188 | 33 | 17758 | 2279 |
NCOR2,SNX27,RAB11FIP4,CENPB,CMTM3,GIT2,PHC2,GLTP,ARHGAP1,CORO1A,PFKFB4,PPP1R9B,RANBP6,SETD1B,ATG9A,LGALS1,POU2F1,MAP7D1,COTL1,ZNF467,ENC1,SH3GL1,DAGLB,ARL6IP5,INTS9,TNFRSF1A,TMEM101,PSAP,PTP4A2,TNFRSF10D,ARHGAP27,MTCH1,TNRC6A |
| 3.735e-02 | -3.29 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | 188 | 33 | 17758 | 2279 |
OXNAD1,MCM6,FAM189B,ST6GAL1,FANCD2,XPO7,RPS6KA5,SPIRE1,FKBP1A,DECR1,ATG3,PDS5B,CCDC112,ERRFI1,LYRM5,NT5M,NARS,GNG7,TEX14,ATP6V0A1,RNH1,CA5B,C1orf174,ANXA1,HLA-DMA,EHMT2,L3MBTL3,HSPBAP1,KLF4,SNAP23,RNF138,NAPA,ECHDC1 |
| 3.735e-02 | -3.29 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | 188 | 33 | 17758 | 2279 |
DMXL2,ADAM19,NPAS2,ZFP36L1,RCAN1,MLH1,DDIT4,WNT2B,KDM5C,MAP3K14,MGLL,MYB,ZBTB17,WDR61,EXOC6B,TFPI,LDHA,MARCKSL1,BRCA1,KLF6,SYT1,ISG15,RDH11,PLIN2,HTR7,CACNB1,FSCN1,ACOX1,COQ9,IFT140,EIF2S1,PPP3CC,RPS6KB1 |
| 3.735e-02 | -3.29 | GSE17721_CTRL_VS_LPS_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_8H_BMDM_UP | 188 | 33 | 17758 | 2279 |
UBN1,OPHN1,C14orf159,FRRS1,FAM50A,ATG3,SOCS6,METTL8,CORO1A,TMEM14C,KLRD1,ZNF124,CDK4,ELOVL6,ANKMY2,ELP3,RNH1,TTYH2,EIF3H,NEU1,SUPT4H1,ELP2,DCXR,NSF,D2HGDH,FDPS,ORC5,H2AFX,DUSP19,MED20,BRCC3,MTMR1,TMEM141 |
| 3.735e-02 | -3.29 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 188 | 33 | 17758 | 2279 |
FEZ2,RHOBTB1,RNF24,RCAN1,MLH1,TUBB6,SLC6A8,PDCD5,PABPC4,SRPRB,PEX7,JAG1,KDELC1,POLR3B,DYNC2H1,TRIP13,HMGCR,ARNTL2,IFRD1,NARS,EIF3J,TFPI,KIF15,TCEB3,ATXN1,RAP1GDS1,CAMSAP2,AGAP1,CRYBG3,FKBP3,PGD,XPNPEP1,SIL1 |
| 3.735e-02 | -3.29 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP | 188 | 33 | 17758 | 2279 |
ZNF254,LETM1,TRIP6,TNFRSF21,HSD17B10,TMEM177,DPM3,SLC29A1,PRKCA,RMI1,NUBPL,GART,COPS3,DNAJB6,MYC,EXOSC4,POLE3,KIAA0922,SLC27A5,PRMT5,SEH1L,MYB,NARS2,RBCK1,RAP1GAP2,UBE2E1,STOML2,PGD,CAT,BAZ2B,DNAJC12,RNF130,ADK |
| 3.735e-02 | -3.29 | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | 188 | 33 | 17758 | 2279 |
BCCIP,GGT1,AUH,CDC42EP2,ATRX,ARL15,RNASEH2B,C1orf50,MCM9,SPG21,THADA,ABCA5,ZDHHC6,SUCLG2,SELT,ANP32B,MET,MAP3K12,MGLL,LYST,HTRA2,FDFT1,VPS13B,CRIM1,MINA,ABCC2,TMEM187,POLG2,TBC1D2,TRMT2A,PUS1,KIF1B,LPP |
| 3.735e-02 | -3.29 | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | 188 | 33 | 17758 | 2279 |
DNAJA4,ZNF516,CUL4A,ATP6V1A,PLRG1,TUBE1,SCAF8,AHCYL2,MAN1A1,NAV1,RDX,PRPS1,SEH1L,HSD17B12,LYST,CSGALNACT2,HMGCR,C21orf58,EVL,PTBP2,SKIV2L2,PRDM1,PPIP5K2,TAF9B,TAF2,LSS,ATAD5,SRBD1,ASB3,PPP3CC,DLX2,BMI1,CEP170 |
| 3.735e-02 | -3.29 | GSE7852_LN_VS_THYMUS_TCONV_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_DN | 188 | 33 | 17758 | 2279 |
EPM2AIP1,MCM10,ARID2,C10orf2,TUBE1,BTBD9,SFI1,NEDD4,IGF2BP3,CEP290,ZFYVE28,USPL1,TIMELESS,VCL,CDK6,EIF4E3,C2orf76,RAP1GAP2,ZBED4,ARHGEF10,LIG4,SLC35D1,SOX4,TRIM37,CENPP,IFT81,ATAD5,SRP68,VCAN,IFT140,CCNB1IP1,DMTF1,SLC16A10 |
| 3.735e-02 | -3.29 | catabolic process | biological process | GO:0009056 | 1809 | 260 | 16441 | 2138 |
GGT1,CUL4A,PRDX6,DCP1B,GYG1,NT5C3A,HMOX2,ABHD6,SYNJ1,UBR5,LPIN1,PABPC4,AMBRA1,TOM1L1,MMP7,RPS16,PMAIP1,RNF111,PPM1K,ACADS,DPF3,ATG9A,UPP1,ALDH1L2,TCEB3,PLCXD2,SPOP,DDAH2,BDH2,XPNPEP1,FIS1,DROSHA,PIK3R4,TATDN3,PLA2G12A,CCDC47,PARN,UBE3A,COPS3,CNOT4,MAP3K12,AGL,PABPC1,USE1,EXOSC2,COL17A1,WDR61,PCCA,EIF4A2,USP10,PLCB1,CPT1A,USP46,ARIH2,IRS1,CAT,DAGLA,KPNA1,RPL28,FGFBP1,UBAP1,VCAN,ZCCHC6,DPEP1,PEX13,CNOT6,C18orf25,CPT1C,GALE,SDSL,TRERF1,LIN28B,PAFAH1B1,PDE3A,DECR1,ERI1,UCHL5,LPIN2,SOCS6,MMP14,TTC3,NT5C,PNPLA4,MGLL,PDK1,MARCH6,NUDT15,PDE8B,FBXL5,CDC16,DCXR,ATG2B,MLH1,RNASEH2B,INPP1,PSMF1,NEDD4,DCTPP1,ANXA5,PHYKPL,UPF2,NLGN3,EXOSC4,NT5M,FBXL19,LYPLA2,DIS3L2,PFKFB4,DDHD1,VPS37A,USP42,LDHA,MRPS10,UBE2K,PDE3B,MMAA,UBC,ECH1,ETFDH,FBXO21,PXDN,COL26A1,ACOX1,SRD5A3,ATM,ANAPC4,DDIT3,CYP24A1,CUL7,HECTD3,SLC25A21,RCHY1,RNF43,SIRT2,BIRC2,PCYOX1L,EDC3,AMPD3,ANAPC1,PHKA1,ATG3,ANAPC11,ANAPC10,HYAL1,OGG1,MPST,PRKACB,LONP1,CDC37,FBXW4,SESN2,RBCK1,TRIM13,ITPA,SKIV2L2,GPCPD1,HSPA5,ATG12,DLST,KIF16B,GLS,HPRT1,ADAM9,NOCT,CHMP4C,USP15,LDAH,FBXO45,XYLB,UBXN1,HSD17B10,SMG7,ZFP36L1,RHBDD1,ETFB,RNF40,PDE10A,PNPLA3,LRSAM1,HSD17B14,NT5E,PDE4A,USP49,PPAT,OBSCN,PSMA1,RNH1,ACOXL,UBE2E1,ISG15,HERPUD1,POP1,HK2,DTD1,TBL1X,BRSK2,PDE9A,AGO3,USP7,CYLD,PAPD4,CEMIP,RPS29,NTSR1,RIPK1,PPP2R2A,RNF24,TNKS1BP1,DENND3,LYPLAL1,UBR1,HIBCH,ETF1,AUP1,HTRA2,TMLHE,PRPF19,MCEE,SKIV2L,COL5A2,RAB7A,ENC1,EDEM2,UBR4,USP36,HYAL3,ARNTL,ATG7,USP11,MUTYH,SMG1,DMGDH,BCKDK,HM13,AUH,PDE4B,TKFC,ADH5,PEX7,ERI3,CD44,FBXO31,FGF2,DHX34,EXOG,PDE2A,NAPEPLD,SMPDL3B,NEU1,CTIF,MFN2,GPC2,DAGLB,CUL2,USP20,EIF2S1,NCBP2,TATDN1,MMP16,GCSH |
| 3.739e-02 | -3.29 | C2H2 zinc finger domain binding | molecular function | GO:0070742 | 15 | 5 | 16491 | 2164 |
HMGA2,EHMT2,SRRM2,MBD2,EHMT1 |
| 3.739e-02 | -3.29 | proteasome binding | molecular function | GO:0070628 | 15 | 5 | 16491 | 2164 |
PSMG1,SACS,ID1,UCHL5,PSMF1 |
| 3.740e-02 | -3.29 | central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV | 48 | 11 | 17775 | 2278 |
FBXL5,BRAF,TP53BP1,DCP1B,TMEM117,INTS12,SLC16A1,LPCAT1,C6orf163,AMBRA1,PARD3 |
| 3.743e-02 | -3.29 | MYEOV2 (myeloma overexpressed 2) | protein interactions | 150678 | 14 | 5 | 16036 | 2270 |
CUL4A,COPS6,COPS5,COPS3,CUL2 |
| 3.743e-02 | -3.29 | GFI1 (growth factor independent 1 transcription repressor) | protein interactions | 2672 | 14 | 5 | 16036 | 2270 |
ZBTB17,EHMT2,KDM1A,ARIH2,CHAF1A |
| 3.743e-02 | -3.29 | MRPS6 (mitochondrial ribosomal protein S6) | protein interactions | 64968 | 14 | 5 | 16036 | 2270 |
CEP126,SREBF2,SRRM2,TRA2A,SRPK2 |
| 3.743e-02 | -3.29 | FTO (fat mass and obesity associated) | protein interactions | 79068 | 14 | 5 | 16036 | 2270 |
TKFC,BCCIP,CNDP2,ZMAT3,LDHA |
| 3.743e-02 | -3.29 | CAV2 (caveolin 2) | protein interactions | 858 | 14 | 5 | 16036 | 2270 |
CSNK2A1,MALL,PTGS1,CAV1,KCNMA1 |
| 3.743e-02 | -3.29 | PHIP (pleckstrin homology domain interacting protein) | protein interactions | 55023 | 14 | 5 | 16036 | 2270 |
IRS1,RNF2,CUL7,CUL4A,SIRT7 |
| 3.743e-02 | -3.29 | SELE (selectin E) | protein interactions | 6401 | 14 | 5 | 16036 | 2270 |
PTK2,PXN,CD44,VCL,GLG1 |
| 3.743e-02 | -3.29 | TRDMT1 (tRNA aspartic acid methyltransferase 1) | protein interactions | 1787 | 14 | 5 | 16036 | 2270 |
NFRKB,COPS6,DDX24,UTP14A,STX1A |
| 3.743e-02 | -3.29 | TRIM36 (tripartite motif containing 36) | protein interactions | 55521 | 14 | 5 | 16036 | 2270 |
ZMAT2,ZNF587,UBC,EIF4A2,TRIM36 |
| 3.743e-02 | -3.29 | Anapc1 (anaphase promoting complex subunit 1) | protein interactions | 17222 | 14 | 5 | 16036 | 2270 |
ANAPC1,CFAP97,CDC16,ANAPC4,ANAPC10 |
| 3.743e-02 | -3.29 | STON2 (stonin 2) | protein interactions | 85439 | 14 | 5 | 16036 | 2270 |
ABL1,FN1,COPS4,SYT1,EPS15L1 |
| 3.743e-02 | -3.29 | PLCB2 (phospholipase C, beta 2) | protein interactions | 5330 | 14 | 5 | 16036 | 2270 |
WDR36,WDR26,TBXA2R,MAP2K3,SNCA |
| 3.743e-02 | -3.29 | POLR3K (polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa) | protein interactions | 51728 | 14 | 5 | 16036 | 2270 |
CRCP,POLR3D,POLR3B,POLR1C,POLR3A |
| 3.743e-02 | -3.29 | RBM33 (RNA binding motif protein 33) | protein interactions | 155435 | 14 | 5 | 16036 | 2270 |
TRMT2A,CSNK2A1,EME1,TOMM34,TERF2 |
| 3.743e-02 | -3.29 | NUP37 (nucleoporin 37kDa) | protein interactions | 79023 | 14 | 5 | 16036 | 2270 |
NUP43,NUP160,NUP133,UBC,SEH1L |
| 3.743e-02 | -3.29 | ELP4 (elongator acetyltransferase complex subunit 4) | protein interactions | 26610 | 14 | 5 | 16036 | 2270 |
SHMT2,ELP2,IKBKAP,SRP68,ELP3 |
| 3.743e-02 | -3.29 | FNBP1L (formin binding protein 1-like) | protein interactions | 54874 | 14 | 5 | 16036 | 2270 |
ACP1,SGSM2,SHMT2,ATG3,SF3A1 |
| 3.743e-02 | -3.29 | RPA4 (replication protein A4) | protein interactions | 29935 | 14 | 5 | 16036 | 2270 |
XPC,PARP2,MUTYH,MSH3,RPA1 |
| 3.743e-02 | -3.29 | MRPS18C (mitochondrial ribosomal protein S18C) | protein interactions | 51023 | 14 | 5 | 16036 | 2270 |
LIG4,SHMT2,TRMT10B,TRA2A,MRPS11 |
| 3.743e-02 | -3.29 | DLC1 (DLC1 Rho GTPase activating protein) | protein interactions | 10395 | 14 | 5 | 16036 | 2270 |
WWC1,CAV1,CUL4A,S100A10,CUL2 |
| 3.747e-02 | -3.28 | chromosome, telomeric region | cellular component | GO:0000781 | 130 | 24 | 17570 | 2233 |
HMBOX1,THOC5,MCM6,SIRT6,ATRX,NAT10,HIST1H4J,MCM2,TNKS1BP1,CDC73,RPA1,TOX4,TERF2IP,SLX4,ACD,TP53BP1,MCM5,NSMCE2,NSMCE1,ORC5,H2AFX,ATM,CTC1,TERF2 |
| 3.748e-02 | -3.28 | zf-CCCH | pfam domains | PF00642 | 36 | 9 | 16629 | 2165 |
TOE1,HELZ,ZFP36L1,ZC3H8,MBNL2,ZC3H3,MBNL1,DHX57,ZC3H13 |
| 3.750e-02 | -3.28 | tube formation | biological process | GO:0035148 | 140 | 26 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,LUZP1,PAX2,FZD3,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SOX4,TCTN1,SKI,HIF1A,SDCCAG8,BCAS3,BMP4,APAF1,PRKACB,STK4,HS2ST1,MTHFD1 |
| 3.751e-02 | -3.28 | V$AMEF2_Q6 | MSigDB lists | V$AMEF2_Q6 | 242 | 41 | 17758 | 2279 |
TNNC1,TTN,PRPF38B,LUZP1,RHOBTB1,DLGAP4,ZFP36L1,BZW2,BIRC2,NEDD4,PABPC4,MTUS1,RTN1,JAZF1,CHD2,TMEM136,TSPAN14,ETV1,SPTAN1,BDNF,FGF9,TLE3,ANKMY2,JMJD1C,PACS1,TBC1D16,MBNL2,SLC50A1,RAD54B,DKK1,HTR7,IFT81,PDLIM1,KPNA3,GTF2A1,LUC7L3,ZNF436,CCDC85B,MID1,C18orf25,C6orf223 |
| 3.754e-02 | -3.28 | Regulation of HSF1-mediated heat shock response | REACTOME pathways | R-HSA-3371453 | 68 | 15 | 8202 | 1117 |
RANBP2,DNAJC2,NUP133,DNAJB6,HSPA5,ATM,NUP43,NUP160,NUP214,HSPA1A,POM121,BAG1,SEH1L,HSPA1B,RPA1 |
| 3.756e-02 | -3.28 | regulation of cell-substrate adhesion | biological process | GO:0010810 | 166 | 30 | 16441 | 2138 |
UNC13D,RELL2,PHLDB2,MINK1,GCNT2,BRAF,FN1,RREB1,NF1,WDPCP,LGALS1,PREX1,SEMA3E,PTK2,MEN1,ONECUT2,RAC3,PIK3CB,PRKCE,SMAD3,COL26A1,S100A10,MMP14,BCAS3,HRG,PLEKHA2,SPOCK2,CDK6,HSD17B12,ANGPT2 |
| 3.758e-02 | -3.28 | CAGGTA_V$AREB6_01 | MSigDB lists | CAGGTA_V$AREB6_01 | 736 | 111 | 17758 | 2279 |
PTP4A1,TCF12,CYLD,RBFOX2,PPARGC1B,HFM1,PPP2R2A,PBX1,RNF43,FAM122B,ST7L,ZNF827,JAG1,SRSF2,RPS6KL1,FSIP2,MMP14,NBEA,ZEB1,CORO1A,FHIT,MGLL,CDK6,PRKACB,MAML3,SRPK2,ACSL5,SOBP,DTNB,GPM6A,SLC3A2,SLC38A1,ENHO,MED27,WDPCP,VSNL1,NFIA,MSRB3,SEMA3F,FKBP3,BTBD11,STOML2,MLLT10,SLC30A3,LUC7L3,ARNTL,HOXA3,CTAGE5,CSMD3,BMI1,TMEM33,HMGA2,PRPF38B,ESCO1,CHST11,JUP,SCAMP3,FN1,PDE4B,LAMTOR3,CCDC7,DNAJC22,TGFB2,KCNJ14,ENOX1,FOXP1,MBNL1,BMP6,FAM49A,BZW2,PTPN2,TECTA,ATXN7L1,ELL,LRP2BP,CACNB2,BUD31,NDRG4,CCDC112,GREB1,RAPGEFL1,S100A14,ERRFI1,LYPLA2,MYB,RABEPK,BDNF,FGF9,MSX1,PXN,VPS37A,RB1CC1,TRA2A,FOXN3,AOC2,ANKMY2,ZC3H18,RYR2,WWC1,PACS1,ST6GALNAC3,PLCB1,NAALADL2,MGAT2,IRS1,CACNB1,CDH24,FDPS,BMP4,MBD6,FNBP1L |
| 3.758e-02 | -3.28 | human chr12q23.3 | chromosome location | human chr12q23.3 | 26 | 6 | 26250 | 2590 |
PWP1,POLR3B,HCFC2,ALDH1L2,C12orf45,BTBD11 |
| 3.759e-02 | -3.28 | negative regulation of biological process | biological process | GO:0048519 | 4447 | 613 | 16441 | 2138 |
THOC5,CHAC1,NUP160,ABHD6,CIAPIN1,AMBRA1,SKI,TOM1L1,SREBF2,ZFHX3,PMAIP1,MAD1L1,PDS5B,ZNF148,FNIP2,KDM5C,HRG,ZNRD1,FXN,AVEN,CDK6,HMBOX1,NRAS,LIMA1,PTPRM,EHMT1,NFIA,C5AR1,MCL1,PYCR1,DDX3X,BRCA2,SUPT4H1,RAD18,RUNX1,TPM1,MEF2C,BANP,TRIP6,KHDRBS1,SIRT7,RSF1,CDC73,ABCA7,CNST,ANP32B,PRMT5,PABPC1,ANGPT2,MYB,HMGCR,PEA15,ZNF675,GATAD2B,GTF2H3,BDNF,IFRD1,WDR61,RB1CC1,PRDM16,EPS15L1,ARID5B,EIF4A2,IDH3G,RYR2,TRIM37,ONECUT2,ZNF655,IRS1,EHMT2,TRAP1,FGFBP1,LEMD3,CDK9,CCDC85B,CNOT6,ARHGAP10,SGSM3,SPRED2,DNM3,MAP2K5,PAFAH1B1,NPAS2,C16orf45,PDK4,MYH9,GRINA,NUP43,STAM,HSPA1A,RPGRIP1L,ACD,ERI1,WAC,MMP14,PEG10,PXK,KMT2D,STAMBP,LGALS1,FGFR1,PDE8B,CDC16,ELP2,ASTN2,PEMT,HIPK2,RPS6KB1,YEATS2,BAG1,MAPT,HMGA2,SHQ1,INSIG2,XPC,ID2,GAS6,AKT1S1,IP6K2,TRIM22,BHLHE40,RNASEH2B,TGFB2,PSMF1,POM121,SNW1,NPRL2,SUV39H2,TAF3,CFDP1,ANXA5,PTGS1,SAMD4A,SOX6,DIS3L2,SPTAN1,FGF9,NXN,IL6R,PDE3B,FOXC1,UBC,ANXA1,OXSR1,TRIB3,NSD1,PXDN,HERC1,GPAM,PSAP,BMP4,IGBP1,ANAPC4,AAMDC,PPARGC1B,POLR1A,CSNK2A1,RNF43,NLE1,BIRC2,ABL2,ECM1,SRSF2,XRCC2,ZNF85,RAN,PTPRK,RBCK1,ATF4,AEBP2,GCNT2,PPARG,BAZ2A,CDK4,HSPA5,TSN,GMFB,ATG12,BRCA1,KCNH2,ZNF91,TCF7L1,TOM1L2,INSIG1,PER1,SOCS4,TNFRSF1A,DPP4,DLX2,BEND6,USP15,CHMP4C,FOXO1,NKD2,LAMTOR3,SMAD7,HES6,BARX2,TRIM15,ZIC2,RNF40,MLX,ABCA5,MBD2,VPS72,SAMD11,NDRG4,GTF2H1,VAPB,CTR9,TIMELESS,WNT16,LRSAM1,NT5E,NAA38,PAXBP1,CRADD,RNH1,SUPT5H,TCF7L2,NR2F1,ATXN7,SYNCRIP,PALB2,IRAK2,TESC,PRKAR2A,USP7,SART1,ID1,CYLD,UPK3B,NDUFAF2,RBFOX2,NTSR1,RIPK1,PAG1,SEMA6A,PLXNB1,KDM1A,ZBTB21,JAG1,NUP133,GRIN2C,UBR1,DNAJB6,IKBKB,RNF2,CORO1A,PRMT3,CTC1,PRPF19,KAT8,EVL,KIRREL2,RAB7A,C1QTNF1,VIM,ENC1,NUP214,SMAD3,RANBP2,RBBP8,SIX5,KLF4,ATG7,EIF2B3,AP2S1,PKIB,PARD3,NIFK,AGO2,FOXP1,HIST2H2AB,IQGAP2,PTPN2,SACS,ANXA7,TMEM161A,HIST2H3D,POLR1B,FBXO31,CD44,FOXN3,TEX14,DHX34,RANGAP1,HIST1H4J,GPNMB,ZRANB3,MKX,DKK1,SET,TBX3,MSH3,BCAS3,GLG1,EIF2S1,FNTB,RBM26,RBPJ,NR2F2,MYCBP2,CUL4A,TNFRSF21,PRKAB2,TMEM109,PRKCA,UBR5,AARS,GIPR,ZFYVE28,PAK1IP1,MEIS3,SEH1L,NR6A1,ATG9A,CUX1,VSNL1,SEMA3F,HSH2D,SON,SAP30BP,GNAI1,GZF1,DOT1L,SPOP,SKIL,DDAH2,TRRAP,SH3RF1,CCNT1,ARL6IP5,HIC2,SEMA3C,TNFRSF10D,NRP1,BMI1,SPOCK3,PTPN14,EFNB2,IFT57,EGR1,DROSHA,ZHX3,ANKRD17,OPHN1,PID1,PDCD5,TGFBR2,CHD5,IGF2BP3,FKBP1A,PRKCE,HR,ASAP1,MYC,IGF2BP1,LPCAT1,CAV2,TERF2,ADARB1,SYNGAP1,RREB1,RAP1GAP2,RAP1B,ARID1A,NELFA,TPRA1,PLCB1,ANGPTL4,CAT,ZNF425,EPRS,HIF1A,PMEPA1,SPEN,PURB,DPEP1,NCOR1,SMYD3,ZNF254,LIN28B,BIRC6,PTPRG,RING1,PDE3A,PAIP2,TERF2IP,ASNS,PPID,UCHL5,SOCS6,TTC3,SERPINH1,KMT2A,NAA35,CASP8AP2,SAP30,BRD4,DLG4,SATB2,DCBLD2,SNCA,VDR,MSX2,CAMK2D,SMARCC1,G6PD,DNAJA3,H2AFX,TRAF3,ANXA2,SETD6,MID1,NCOR2,NOSTRIN,BRAF,TCF3,NFX1,RTN4,MLH1,OPA1,NOL3,RPS6KA5,FOXO3,GIGYF2,MAD2L2,NEDD4,ABL1,RGS17,TRIAP1,NISCH,RDX,NLGN3,CELF1,YBX3,ERRFI1,CLK2,SLC40A1,APEX1,ZFYVE1,FZD3,KCNMA1,TBRG4,PTK2,OASL,POLR2A,KLHL22,IREB2,ATM,DDIT3,STK4,KAT6A,MVK,UBN1,KMT2E,NF1,ATRX,BCOR,SIRT2,SMARCB1,DST,ANAPC1,RAP1A,YLPM1,JAZF1,GPR87,ANAPC11,ANAPC10,HYAL1,ZEB1,RELB,KIAA0922,SLC35C2,HCFC2,OGG1,CARM1,TRIM14,PRKACB,SRPK2,ZBTB17,TNK2,DEAF1,TRIM13,SIRT6,TFPI,ARRDC3,MINA,HDAC8,CAV1,SOX4,SERGEF,TAF9B,UBTF,PAF1,EIF4ENIF1,SUFU,GATA6,DNAJC1,CC2D1B,CLU,ZC3H8,NOCT,TNRC6A,CHST11,FN1,STXBP6,PAX2,UBXN1,RHBDD1,DDIT4,ELL,P3H1,ATXN2,SEMA3D,NRIP1,POLR1E,XPO5,PSMA1,WWC1,LIG4,PRDM1,ISG15,UBE2E1,HERPUD1,MYBBP1A,BICD1,HK2,RRAGA,PTRH2,ZFP90,TBL1X,IFITM2,AGO3,N4BP2L2,ZNF706,CHMP2A,DLL4,FEZ2,ASH1L,PCNT,MMRN2,PBX1,SMARCA4,ST7L,CSTA,PIBF1,SBDS,KCTD11,RRN3,MPHOSPH10,LYPLAL1,SOCS1,FHIT,MET,VCL,HTRA2,TMLHE,MOSPD1,PRAME,PHLDB2,COL5A2,PTBP2,SFSWAP,POU2F1,ATXN1,WARS,BATF3,ZC3H12A,IKZF4,ADNP,ARNTL,DUSP19,DNAJC2,DNAJA4,SUPT6H,H2AFJ,PDE4B,TKFC,CHCHD10,IGF2BP2,ATF7IP,SEMA3E,PPP1R1C,SOGA1,BMP6,SFI1,PRKCH,STC2,UTS2,AMOT,DMRT1,PPP1R9B,MSX1,KDM5B,FGF2,CRIM1,KDM5A,PSPC1,SCMH1,PHACTR2,MEN1,PDE2A,HSPA1B,MFN2,RERE,GADD45A,CUL2,NCBP2,POLR1C,NFKBIB,ZAK |
| 3.762e-02 | -3.28 | HMG_box_dom | interpro domains | IPR009071 | 54 | 12 | 18293 | 2341 |
TOX4,UBTF,TCF7L1,PMS1,KMT2D,CHD3,WDHD1,CCDC124,KMT2C,SOX4,SOX6,TCF7L2 |
| 3.764e-02 | -3.28 | zf-C3HC4 | pfam domains | PF00097 | 59 | 13 | 16629 | 2165 |
PCGF3,TRIM13,RAD18,SH3RF1,RNF138,RNF2,TRIM15,BRCA1,BMI1,MID1,RING1,RNF114,TRIM36 |
| 3.765e-02 | -3.28 | regulation of epithelial cell migration | biological process | GO:0010632 | 153 | 28 | 16441 | 2138 |
DLL4,AMOTL1,EVL,MAP2K5,RREB1,MMRN2,FGF2,NF1,PTPRM,PTK2,PTPRG,PRKCA,TGFB2,FOXP1,PRKCE,HIF1A,KLF4,BCAS3,HYAL1,ADAM9,SCARB1,BMP4,HRG,NR2F2,MET,NRP1,AMOT,ANGPT2 |
| 3.774e-02 | -3.28 | REACTOME_METABOLISM_OF_NON_CODING_RNA | MSigDB lists | REACTOME_METABOLISM_OF_NON_CODING_RNA | 48 | 11 | 17758 | 2279 |
GEMIN5,RANBP2,NUP133,NCBP2,GEMIN4,NUP43,PRMT5,NUP214,POM121,CLNS1A,SEH1L |
| 3.774e-02 | -3.28 | GNF2_DENR | MSigDB lists | GNF2_DENR | 48 | 11 | 17758 | 2279 |
MPHOSPH10,DDX50,SYNCRIP,BCAS2,RWDD1,HNRNPR,KHDRBS1,HNRNPH3,MRPS10,MAPK1IP1L,DENR |
| 3.778e-02 | -3.28 | striated muscle tissue development | biological process | GO:0014706 | 266 | 45 | 16441 | 2138 |
TNNC1,PTCD2,TTN,DLL4,EGR1,NF1,SMAD7,ID2,TGFB2,MBNL1,FLNB,SKI,FKBP1A,SNW1,NEBL,DSG2,NDRG4,CAV2,SOX6,SAP30,KDM6B,IFRD1,SIRT6,GPCPD1,RYR2,MEF2D,ARID1A,CAV1,DSP,FOXC1,CXADR,SKIL,CAMK2D,GATA6,LEMD3,MKL2,TBX3,ATG7,SVIL,SEMA3C,RBPJ,TPM1,NR2F2,PDLIM5,MEF2C |
| 3.790e-02 | -3.27 | GNF2_MSH6 | MSigDB lists | GNF2_MSH6 | 31 | 8 | 17758 | 2279 |
RFC4,RFC3,MTHFD2,GNL3,MRPS27,ADSL,RAN,MLH1 |
| 3.790e-02 | -3.27 | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | 31 | 8 | 17758 | 2279 |
PTP4A1,ID1,AHNAK,FN1,MYC,ITGA2,SEMA3C,RDX |
| 3.790e-02 | -3.27 | CARBON_OXYGEN_LYASE_ACTIVITY | MSigDB lists | CARBON_OXYGEN_LYASE_ACTIVITY | 31 | 8 | 17758 | 2279 |
AUH,ALAD,APEX1,CA11,CA5B,GMDS,OGG1,ECH1 |
| 3.790e-02 | -3.27 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 31 | 8 | 17758 | 2279 |
SLC7A1,SLC3A2,SLC38A5,SLC7A11,SLC38A1,SLC38A2,SLC16A10,SLC43A1 |
| 3.790e-02 | -3.27 | GRADE_COLON_VS_RECTAL_CANCER_UP | MSigDB lists | GRADE_COLON_VS_RECTAL_CANCER_UP | 31 | 8 | 17758 | 2279 |
ALG5,INSIG2,DDX50,RAD18,LAGE3,UMPS,RNASEH2B,ZAK |
| 3.790e-02 | -3.27 | SRPK3 (SRSF protein kinase 3) | protein interactions | 26576 | 60 | 14 | 16036 | 2270 |
SNU13,MYBBP1A,PHF5A,HNRNPR,GNL3,RSL1D1,NOC3L,YBX3,SON,SRRM2,PDCD11,FTSJ3,HNRNPM,NOP56 |
| 3.790e-02 | -3.27 | RBM4 (RNA binding motif protein 4) | protein interactions | 5936 | 60 | 14 | 16036 | 2270 |
TRIB3,CUL7,PTBP2,FN1,PRPF31,LRP2BP,COPS5,HNRNPH3,AGO2,CUL2,COPS6,PABPC1,HNRNPM,RPA1 |
| 3.790e-02 | -3.27 | SPACA1 (sperm acrosome associated 1) | protein interactions | 81833 | 60 | 14 | 16036 | 2270 |
DNM3,DAGLB,INTS7,C17orf80,TMEM126B,FAM171A2,AP1M1,LTN1,KIAA1586,SLC25A26,GBF1,MAD2L2,LMBRD2,VPS13B |
| 3.792e-02 | -3.27 | ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | MSigDB lists | ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | 72 | 15 | 17758 | 2279 |
PTRF,EGR1,INSIG1,CPOX,HSPA5,ID2,RTN4,MCL1,KLF6,HSPA1A,HERPUD1,HSPA1B,DDIT4,MYB,MEF2C |
| 3.792e-02 | -3.27 | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | 72 | 15 | 17758 | 2279 |
AHNAK,FAM189B,WLS,ELOVL6,ANKRD33B,DSG2,MAPK8IP3,SQLE,GTF2H1,ANXA2,MDN1,ST3GAL6,TBXA2R,PKIB,ANXA1 |
| 3.792e-02 | -3.27 | SHFM1 (split hand/foot malformation (ectrodactyly) type 1) | protein interactions | 7979 | 135 | 27 | 16036 | 2270 |
USP7,EIF3C,RBM33,PSMG1,BRCA1,MARCH6,LENG8,UBR5,UBR4,PSMF1,UBC,TAF2,UBE3A,BRCA2,INTS7,UBR1,INTS5,UCHL5,ATXN2,CUL2,INTS9,LTN1,MDN1,BAG1,CPSF3L,TOP1,USP15 |
| 3.794e-02 | -3.27 | maxilla | COSMIC cancer mutations | maxilla | 66 | 14 | 17775 | 2278 |
RBM20,BRAF,NRAS,SUFU,SPEN,TBXAS1,SYNPO,SLC26A11,CDC73,SOX6,MGA,MTHFD1,FAM184A,SMARCB1 |
| 3.797e-02 | -3.27 | RPS7 (ribosomal protein S7) | protein interactions | 6201 | 159 | 31 | 16036 | 2270 |
SNU13,FN1,DDX24,DDX18,GNL3,SIRT7,RPS29,NOL6,LAMTOR3,RSL1D1,WDR26,BRCA1,EIF2A,NOP58,RPA1,NOP56,DDX3X,TSR1,MPHOSPH10,RPS16,NEK6,GADD45A,COPS5,BUD31,ETF1,RNF2,UPF2,FBL,SRRM2,HNRNPM,RPS6KB2 |
| 3.806e-02 | -3.27 | tissue morphogenesis | biological process | GO:0048729 | 564 | 88 | 16441 | 2138 |
PTCD2,DLL4,LUZP1,PAFAH1B1,MKS1,PBX1,ENAH,RPGRIP1L,SKI,JAG1,MMP14,VPS52,CCDC40,MET,VCL,PRKACB,DEAF1,SIRT6,PTPRM,WLS,GRHL3,MTHFD1L,MEGF11,SOX4,TCTN1,DSP,RAB10,FGFR1,GZF1,VDR,SMAD3,MSX2,TCF7L1,HIPK2,KLF4,ITGA2,ARL13B,SLC4A7,SEMA3C,RUNX1,TPM1,NRP1,LAMA5,PARD3,MEF2C,EFNB2,HMGA2,TNNC1,TTN,IFT57,CELSR1,PAX2,SMAD7,ZIC2,TRIM15,LIAS,SEMA3E,TGFB2,TGFBR2,FKBP1A,CEP290,MYC,PVRL3,NDRG4,TIMELESS,WNT16,CD44,MTHFD1,KDM6B,MSX1,PXN,FGF2,FZD3,RDH10,SETD2,RYR2,ARID1A,FOXC1,DKK1,HIF1A,TBX3,ARHGAP12,RBPJ,BMP4,APAF1,ITGB4,STK4,HS2ST1 |
| 3.808e-02 | -3.27 | human chr17q21 | chromosome location | human chr17q21 | 47 | 9 | 26250 | 2590 |
AOC3,NBR2,JUP,NSF,FMNL1,AOC2,ATP6V0A1,BRCA1,MAP3K14 |
| 3.810e-02 | -3.27 | RIBONUCLEOPROTEIN_COMPLEX | MSigDB lists | RIBONUCLEOPROTEIN_COMPLEX | 142 | 26 | 17758 | 2279 |
APEX1,PRPF31,MRPL10,NOL6,PSMA1,MRPS10,SF3A3,DKC1,PDCD7,SRA1,SERP1,MRPS11,POP1,RPP30,SNW1,PHF5A,BCAS2,HNRNPR,ATXN2,SRP68,EIF2S1,GEMIN4,TROVE2,SRP14,HNRNPM,SF3A1 |
| 3.811e-02 | -3.27 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | 195 | 34 | 17758 | 2279 |
FEZ2,RHOBTB1,PRKAB2,ATF7IP,PITPNM1,PIP4K2A,IGSF1,ABCA7,ZNF608,NISCH,TRIAP1,GPR87,GLTP,ERRFI1,ITGAX,PRKACB,FAM120B,KLRD1,TLE3,PPP1R21,C1QTNF1,PREX1,ENC1,PDE3B,ARIH2,POLR2A,BTBD11,ZNF708,SRCAP,FAM135A,ZBTB12,IRAK2,NFRKB,WDR33 |
| 3.811e-02 | -3.27 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | 195 | 34 | 17758 | 2279 |
IMMP2L,MIF4GD,HM13,TMEM109,SLC9B2,AHCYL2,ECM1,ERI1,MCM5,PYCRL,KDELC1,POLE3,HTRA2,MTHFD1,EIF4E3,LAMC1,WLS,ARHGEF12,PRDM1,BRCA1,SLC35D1,ARRDC4,ODC1,HSD3B7,IKZF4,PMEPA1,DNAJC1,SNAP23,RAD51B,PTRH2,KLHDC4,MAGI1,TMEM158,GCSH |
| 3.812e-02 | -3.27 | Host Interactions with Influenza Factors | REACTOME pathways | R-HSA-168253 | 40 | 10 | 8202 | 1117 |
RANBP2,KPNA1,KPNA3,NUP133,NUP43,NUP160,NUP214,ISG15,POM121,SEH1L |
| 3.817e-02 | -3.27 | AGCATTA,MIR-155 | MSigDB lists | AGCATTA,MIR-155 | 129 | 24 | 17758 | 2279 |
ANTXR2,SSH2,RREB1,MYO10,ARID2,CUX1,WWC1,SMARCA4,ARL5B,CDC73,SKI,CHD7,PTPN2,LRP1B,FAM135A,SOCS1,HIF1A,ZNF236,BCAP29,MAP3K14,TSPAN14,ZMYM2,ZNF518B,MYB |
| 3.820e-02 | -3.26 | blood vessel development | biological process | GO:0001568 | 438 | 70 | 16441 | 2138 |
DLL4,CUL7,ID1,LUZP1,MMRN2,NF1,MFGE8,MYH9,PRKCA,CHD7,JAG1,ECM1,SHC1,MMP14,HRG,SRPK2,FMNL3,CAV1,SOX4,FLVCR1,FGFR1,WARS,ZC3H12A,GATA6,MKL2,HOXA3,SEMA3C,ANXA2,NRP1,LAMA5,MEF2C,EFNB2,FOXO1,FN1,EGR1,ANKRD17,SMAD7,JMJD6,ZFP36L1,SEMA3E,TGFB2,TGFBR2,NEDD4,MCAM,AMOT,ANGPT2,PKNOX1,FGF9,WARS2,FGF2,SETD2,PRDM1,PTK2,ARID1A,PDE3B,PIK3CB,FOXC1,ANGPTL4,TCF7L2,HIF1A,LEMD3,TBX3,BCAS3,BMP4,RBPJ,NR2F2,DHCR7,DDIT3,STK4,KAT6A |
| 3.826e-02 | -3.26 | PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase) | protein interactions | 5110 | 94 | 20 | 16036 | 2270 |
SEC24A,KLHL24,YDJC,CUL7,FN1,TPM4,KLHL18,C11orf54,UBC,TRAP1,CHD3,TP53BP1,PYCRL,COPS5,CUL2,SVIL,ZRANB2,PFDN2,TERF2,RPS6KB2 |
| 3.826e-02 | -3.26 | SKAP1 (src kinase associated phosphoprotein 1) | protein interactions | 8631 | 94 | 20 | 16036 | 2270 |
MYCBP2,SKAP2,SUPT6H,SUGCT,POLA1,POLR1A,ELP3,UTP15,PPHLN1,PUSL1,POLR3A,PER1,SETD5,ZNHIT6,ATXN2,CUL2,POLR1B,POLR3B,MTMR1,POLR1E |
| 3.833e-02 | -3.26 | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | 66 | 14 | 17758 | 2279 |
SUB1,SLC3A2,ATF4,PDK1,PAM,ACP1,PRDM1,CAV1,SPATS2,BMI1,BMP6,DDIT3,PABPC4,NAMPT |
| 3.833e-02 | -3.26 | RAMASWAMY_METASTASIS_UP | MSigDB lists | RAMASWAMY_METASTASIS_UP | 66 | 14 | 17758 | 2279 |
FAM98A,MSX2,PCNT,UBN1,ITPA,SPEN,GPN1,UPF2,CHD2,WDR37,TRIM37,POM121,TMPO,VPS13B |
| 3.833e-02 | -3.26 | AGGAGTG,MIR-483 | MSigDB lists | AGGAGTG,MIR-483 | 66 | 14 | 17758 | 2279 |
UTP14A,RB1CC1,SFSWAP,SETD2,RIOK3,HIC2,R3HDM1,FAM126B,PDCD7,SLC6A8,SON,USP46,AMBRA1,RAB10 |
| 3.834e-02 | -3.26 | GALE_APL_WITH_FLT3_MUTATED_UP | MSigDB lists | GALE_APL_WITH_FLT3_MUTATED_UP | 54 | 12 | 17758 | 2279 |
TCF12,CHD9,RFC3,CDC16,LARS2,LUC7L3,GEMIN4,HEATR1,NOLC1,CSNK1A1,MTMR1,PSMF1 |
| 3.834e-02 | -3.26 | HALLMARK_TGF_BETA_SIGNALING | MSigDB lists | HALLMARK_TGF_BETA_SIGNALING | 54 | 12 | 17758 | 2279 |
SMAD3,FKBP1A,SKIL,NCOR2,ID1,IFNGR2,PMEPA1,CDK9,HIPK2,SMAD7,ID2,SKI |
| 3.834e-02 | -3.26 | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | 54 | 12 | 17758 | 2279 |
TTN,DNMBP,SYT17,CELSR1,C11orf80,ATXN1,MARS,SPATS2L,PNMA1,SPOCK2,WARS,LPP |
| 3.838e-02 | -3.26 | SWEET_LUNG_CANCER_KRAS_UP | MSigDB lists | SWEET_LUNG_CANCER_KRAS_UP | 472 | 74 | 17758 | 2279 |
ADAM19,LPCAT3,GRINA,HSPA1A,NOP56,TOM1L1,SPG21,SHC1,ZDHHC6,SLC38A2,RELB,ME1,ITGAX,ACSL5,GARS,KRT7,PPARG,CMIP,MTIF2,WLS,GNL3,CPOX,HSPA5,ATOX1,ATP6V0A1,COTL1,OSBPL1A,PLIN2,HLA-DMA,SH3RF1,G6PD,MBTD1,CTAGE5,CLU,TROVE2,HM13,BRAF,ST6GAL1,UBXN1,ID2,APRT,SSR4,BHLHE40,PHLDA2,MAN1A1,TANK,PTGS1,CLDND1,CD44,ERRFI1,LPCAT1,PABPC1,ATP6V0D1,PSAT1,APEX1,LAMC1,TSTA3,LDHA,TPM4,NR2F1,HSPA1B,RDH11,GADD45A,EHMT2,RPL28,DSC2,HIF1A,HK2,SLC16A1,PSAP,BMP4,PFDN2,CNDP2,POLR1C |
| 3.840e-02 | -3.26 | histone methyltransferase activity (H3-K4 specific) | molecular function | GO:0042800 | 20 | 6 | 16491 | 2164 |
ASH1L,KMT2D,SETD1B,KMT2C,KMT2A,KMT2E |
| 3.843e-02 | -3.26 | CTTTAAR_UNKNOWN | MSigDB lists | CTTTAAR_UNKNOWN | 918 | 136 | 17758 | 2279 |
IMMP2L,DPH1,MFGE8,SLC25A21,ADAMTS6,BIRC2,GABPB2,AHCYL2,SMARCB1,SRSF2,NSRP1,JAZF1,CHD2,KDM5C,SLC25A23,CDC37,SRPK2,DPF3,GPM6A,ARRDC3,CUX1,TCEB3,GMFB,VSNL1,SON,STOML2,GNAI1,C1orf122,TCF7L1,TRRAP,GATA6,TP53BP1,ARL6IP5,LUC7L3,CTAGE5,RIOK1,COPS6,FIP1L1,MAGI1,MEF2C,FOXO1,LRRC28,STXBP6,OPHN1,ZFP36L1,ZIC2,XPO7,ABCA7,NAMPT,PRKCE,TECTA,PDE10A,TIMELESS,CALN1,CNOT4,SERBP1,MSI2,KRT20,SIK3,BDNF,IFT43,USP49,PRDM16,EIF4A2,RDH10,JMJD1C,PTPN12,PRDM1,MBNL2,ONECUT2,ITPRIPL1,GTF2A1,PMEPA1,HMBS,MB21D2,GALE,NR2C2AP,FEZ2,MAP2K5,TRERF1,OSBPL9,C1QTNF7,PBX1,CSTA,LCLAT1,RPS6KL1,IKBKB,VGF,NBEA,ETF1,ADCK4,PXK,SOBP,WDPCP,POU2F1,ATP6V0A1,MEF2D,ERC1,UBR4,FKBP3,USP36,MSX2,LMBR1L,HOXA3,H2AFX,MAP3K13,KLC4,RCAN1,JMJD6,RTN4,IP6K2,TGFB2,PIP4K2A,PHLDA2,NEDD4,HAS3,NLGN3,TTC17,ERRFI1,ZNF710,AMOT,TOP1,TSHZ1,FGF9,AGPAT4,FOXN3,NXN,PDE3B,NAALADL2,RERE,ARID3B,TBX3,BCAS3,NR2F2,KIF1B,KAT6A |
| 3.850e-02 | -3.26 | TACAATC,MIR-508 | MSigDB lists | TACAATC,MIR-508 | 60 | 13 | 17758 | 2279 |
HMGA2,BDNF,SUB1,ADNP,KLF4,EIF3J,LAMTOR3,PURB,MAPK1IP1L,RSBN1,ARHGEF12,BMI1,SMG1 |
| 3.850e-02 | -3.26 | MAGNESIUM_ION_BINDING | MSigDB lists | MAGNESIUM_ION_BINDING | 60 | 13 | 17758 | 2279 |
ABL2,ABL1,OXSR1,SIK3,HPRT1,MTHFD2,NEK6,BRSK2,ZAK,TESC,PRKACB,STK4,SRPK2 |
| 3.850e-02 | -3.26 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS | 60 | 13 | 17758 | 2279 |
TOX4,GEMIN5,PRKCE,SPG21,ALAD,HARS,MTIF2,FAM114A2,CLEC16A,CUX1,TCEB3,MYO7A,VPS52 |
| 3.858e-02 | -3.25 | transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0007178 | 226 | 39 | 16441 | 2138 |
CGN,NCOR2,ID1,EGR1,SMAD7,TGFB2,TGFBR2,BMP6,SKI,FKBP1A,SNW1,SUB1,UCHL5,MYC,RNF111,PTPRK,MSX1,PXN,GCNT2,FERMT2,RYR2,VIM,PTK2,MEN1,UBC,BTBD11,SMAD3,SKIL,MSX2,PMEPA1,CCNT1,HIPK2,E2F4,CDK9,ADAM9,BMP4,NCOR1,PARD3,USP15 |
| 3.873e-02 | -3.25 | Circadian rhythm pathway | Pathway Interaction DB | circadianpathway | 14 | 5 | 2227 | 319 |
TIMELESS,BHLHE40,NPAS2,PER1,ARNTL |
| 3.880e-02 | -3.25 | CHICAS_RB1_TARGETS_GROWING | MSigDB lists | CHICAS_RB1_TARGETS_GROWING | 229 | 39 | 17758 | 2279 |
MCM6,EGR1,CCDC53,ATRX,STXBP6,ADAMTS6,PHGDH,DDIT4,PCDH7,ANKRD13A,ASNS,PTRF,TIMELESS,SHMT2,TTC3,PCK2,TMPO,DPF3,RFC4,PSAT1,THSD4,ALDH1L2,KCNMA1,ARID5B,PEAR1,CAV1,MCM2,CORIN,HPRT1,RBBP8,SMARCC1,POLE2,ARL4A,RNF138,CLU,NR2F2,NRP1,TSPAN5,RBP1 |
| 3.882e-02 | -3.25 | regulation of mitotic nuclear division | biological process | GO:0007088 | 134 | 25 | 16441 | 2138 |
PPP1R9B,CHMP2A,CUL7,TEX14,CSNK2A1,SIRT2,MAD2L2,UBE2E1,TOM1L1,ANAPC1,KLHL22,CDC16,NEK6,TOM1L2,NSMCE2,ANAPC11,ANAPC10,MAD1L1,ATM,BMP4,PRMT5,CAV2,DMRT1,ANAPC4,CHMP4C |
| 3.882e-02 | -3.25 | neutral lipid metabolic process | biological process | GO:0006638 | 134 | 25 | 16441 | 2138 |
ACSL5,INSIG2,ELOVL6,AGPAT4,GPAT3,TNXB,CAV1,ABHD6,LCLAT1,CPT1A,LPIN1,SNCA,DAGLA,CAT,INSIG1,LPIN2,ACOT11,GPAM,PNPLA3,SLC27A5,MGLL,LPCAT1,PRKACB,HSD17B12,SLC25A1 |
| 3.893e-02 | -3.25 | AIMP2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2) | protein interactions | 7965 | 77 | 17 | 16036 | 2270 |
DEAF1,FN1,TFIP11,PCMT1,MARS,CEP126,BLOC1S4,BIRC2,CIAPIN1,ZC3H12A,TERF2IP,EPRS,RARS,BCAS2,CHD3,TANK,TRMT2A |
| 3.893e-02 | -3.25 | TOLLIP (toll interacting protein) | protein interactions | 54472 | 77 | 17 | 16036 | 2270 |
TRIP6,RBFOX2,SMAD7,ATXN1,RCAN1,CAV1,BHLHE40,BIRC2,UBC,HERPUD1,TOM1L1,ANKRD13A,TOM1L2,TBX3,IRAK2,PEG10,N4BP2 |
| 3.893e-02 | -3.25 | SRSF11 (serine/arginine-rich splicing factor 11) | protein interactions | 9295 | 77 | 17 | 16036 | 2270 |
SART1,SNU13,UTP14A,TFPI,CSNK2A1,PHGDH,SON,TOX4,SRSF2,GATC,TANK,ZRANB2,SRRM2,CDK6,PRPF19,TOP1,TERF2 |
| 3.893e-02 | -3.25 | NCOA2 (nuclear receptor coactivator 2) | protein interactions | 10499 | 77 | 17 | 16036 | 2270 |
PPARG,KIF5A,CDK4,WDHD1,BRCA1,UBR5,CAD,VDR,SNW1,SRCAP,CCNT1,HIF1A,ANKRD11,DLX2,ETV1,CARM1,MEF2C |
| 3.894e-02 | -3.25 | Infectious disease | REACTOME pathways | R-HSA-5663205 | 347 | 59 | 8202 | 1117 |
CHMP2A,TAF1,GTF2H2C,VTA1,AK6,RPS29,NUP43,AP1B1,NUP160,PSMF1,HSPA1A,MAP2K3,POM121,ELL,RPS16,NUP133,TAF3,BANF1,AP1M1,GTF2H1,RAN,SEH1L,ANTXR2,GTF2H3,VPS37A,RNMT,TCEB3,LIG4,PSMA1,PACS1,RANGAP1,SNAP25,NELFA,SUPT5H,SYT1,NUP214,ISG15,POLR2A,UBC,HSPA1B,TAF9B,TAF2,RANBP2,KPNA1,SUPT4H1,KPNA3,GTF2A1,RPL28,CCNT1,STX1A,CDK9,VPS37B,TAF4,NCBP2,TAF12,XRCC4,MAP2K4,AP2S1,CHMP4C |
| 3.896e-02 | -3.25 | POT1 (protection of telomeres 1) | protein interactions | 25913 | 202 | 38 | 16036 | 2270 |
SARS,MVK,SULT1C2,TRIM16,KHDRBS1,RTN4,ZFP36L1,NOL3,C15orf57,HSPA1A,SBDS,TERF2IP,ZBED2,CNST,BCAS2,ACD,TMSB10,PHYKPL,CORO1A,TOMM34,TERF2,NUDC,SPTAN1,DBN1,EVL,ANKMY2,LDHA,SULT4A1,PCMT1,NCDN,YTHDF2,DDX3X,AHNAK,HLCS,ARID3B,HOXA3,ZNF32,ANXA2 |
| 3.901e-02 | -3.24 | negative regulation of cellular catabolic process | biological process | GO:0031330 | 160 | 29 | 16441 | 2138 |
FEZ2,SIRT6,UBXN1,OPHN1,TEX14,DHX34,CSNK2A1,SIRT2,PSMF1,MAD2L2,UBE2E1,DDIT4,ANAPC1,KLHL22,CDC16,SMARCC1,HERC1,WAC,ANAPC11,ANAPC10,ATG7,RRAGA,MAD1L1,ATM,FHIT,ANXA2,MET,PABPC1,ANAPC4 |
| 3.901e-02 | -3.24 | Cysteine and methionine metabolism | KEGG pathways | hsa00270 | 37 | 9 | 6908 | 881 |
SRM,SDSL,MRI1,LDHA,AHCYL1,MTR,MAT2A,AHCYL2,MPST |
| 3.901e-02 | -3.24 | Cysteine and methionine metabolism | KEGG pathways | ko00270 | 37 | 9 | 6908 | 881 |
SRM,SDSL,MRI1,LDHA,AHCYL1,MTR,MAT2A,AHCYL2,MPST |
| 3.903e-02 | -3.24 | human chr1p13.2 | chromosome location | human chr1p13.2 | 40 | 8 | 26250 | 2590 |
SLC16A1-AS1,NRAS,BCAS2,TSPAN2,AP4B1,RSBN1,ST7L,AHCYL1 |
| 3.905e-02 | -3.24 | POLR2E (polymerase (RNA) II (DNA directed) polypeptide E, 25kDa) | protein interactions | 5434 | 100 | 21 | 16036 | 2270 |
CUL7,POLR1A,TCEB3,BRCA1,TTI1,SUPT5H,POLR2A,NEDD4,POLR3A,RPA1,POLR3D,INTS5,MYC,COPS5,RNF2,POLR1B,POLR3B,USP11,POLR1C,ZNRD1,SMG1 |
| 3.905e-02 | -3.24 | CAPN1 (calpain 1, (mu/I) large subunit) | protein interactions | 823 | 100 | 21 | 16036 | 2270 |
BCCIP,FN1,GINS3,SKIV2L2,ATP6V1A,SIRT7,RAP1GDS1,VIM,EIF2A,BZW2,GLS,SYNCRIP,PALB2,HNRNPR,HIF1A,G6PD,FNTB,PRMT5,CNDP2,NIT1,SPTAN1 |
| 3.905e-02 | -3.24 | morphogenesis of embryonic epithelium | biological process | GO:0016331 | 147 | 27 | 16441 | 2138 |
DEAF1,IFT57,CELSR1,LUZP1,PAX2,FZD3,RDH10,SETD2,GRHL3,MKS1,ENAH,ZIC2,LIAS,MTHFD1L,ARID1A,SOX4,TCTN1,SKI,HIF1A,WNT16,BMP4,APAF1,LAMA5,PRKACB,STK4,HS2ST1,MTHFD1 |
| 3.906e-02 | -3.24 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_DN | 182 | 32 | 17758 | 2279 |
NOMO3,AOC3,CELSR3,C10orf2,TMEM177,SSBP2,ABHD6,SLC39A1,DST,PUS3,RPS16,VPS52,PNPLA4,PLEKHA4,ZNF646,RABEPK,SRPK2,LRRC20,TIMM8B,GLS,KLHL22,BICD1,WDR5B,DNAJA3,LARGE,RRAGA,ALKBH1,PTRH2,UMPS,DLX2,MED20,ZAK |
| 3.906e-02 | -3.24 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 182 | 32 | 17758 | 2279 |
ITPRIP,RIPK1,ZFP36L1,URB1,CIAPIN1,DOPEY1,SH2B3,PUS3,SURF2,ALKBH8,MTHFD2L,ZNF3,SNAPC5,METTL1,ZNF234,DDX28,GON4L,AGPAT4,NOL6,UTP15,TCEB3,ENC1,GZF1,ANXA1,FBXO21,SYNCRIP,HSPBAP1,ZZEF1,SRFBP1,TBL1X,ZC3H8,ZSWIM6 |
| 3.906e-02 | -3.24 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | 182 | 32 | 17758 | 2279 |
JUP,LRRC28,PAFAH1B1,SIRT7,SLC25A12,PABPC1L,SAFB2,FAM8A1,SFI1,ANXA10,TOX4,AP1M1,TMEM120B,ACADS,TNK2,AKAP8L,LAMC1,ZFYVE1,FGF2,PPP1R21,MARCH6,LENG8,HELZ,GLG1,VPS13D,IFT140,CNOT6,ABCC3,NFRKB,PSAP,PTPN14,TMCC1 |
| 3.906e-02 | -3.24 | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP | MSigDB lists | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP | 182 | 32 | 17758 | 2279 |
MYCBP2,TTN,CLDN15,PCNT,ST6GAL1,C14orf159,IP6K2,FOXO3,FAM8A1,CLCN6,NIPSNAP1,SIK3,ZCCHC14,AKAP8L,BAZ2A,GLTSCR2,PSPC1,PTPRM,ATXN1,C11orf49,AKAP13,ARIH2,APBB3,LMBR1L,HSPBAP1,ATM,ARHGAP12,WDR33,IGBP1,KIF1B,LRRC37A,N4BP2L2 |
| 3.907e-02 | -3.24 | GGGTGGRR_V$PAX4_03 | MSigDB lists | GGGTGGRR_V$PAX4_03 | 1241 | 180 | 17758 | 2279 |
ARHGAP26,PPARGC1B,WDR13,TRPM6,CSNK2A1,SBF2,SMARCB1,TOM1L1,SRSF2,SREBF2,S100A10,AP1M1,HYAL1,ZEB1,CDK6,FLNC,FMNL3,HMBOX1,TXLNG,BAZ2A,ANK2,CDK4,ARRDC3,C11orf80,ATG12,HDAC8,ZDHHC14,KRTCAP2,KCNH2,SLC9A5,YTHDF2,SPOP,MLLT10,SKIL,DDAH2,EIF4ENIF1,AHNAK,GATA6,TP53BP1,TMEM139,RAD51B,BLMH,ZNF532,EFNB2,TNNC1,TTN,JUP,ZIC2,EVPL,XPO7,KCNJ14,PITPNM1,DDIT4,MTUS1,PRKCE,UBE3A,HR,SLC38A5,TNPO3,IGF2BP1,CNOT4,RABEPK,COL17A1,STAG1,ELOVL6,JMJD1C,KIAA0586,PTPN12,MEX3B,PRDM1,IMPDH2,CPT1A,NR2F1,NCDN,IRS1,DYNC1H1,SPAG9,SYNCRIP,EHMT2,HIF1A,SPEN,VCAN,HK2,TBCK,CYLD,DLL4,TRERF1,PAFAH1B1,ATP6V1A,ZBTB37,C1QTNF7,MAB21L3,TNXB,PBX1,RADIL,TNKS1BP1,SEMA6A,IGSF1,ZNF827,ESAM,SHC1,SOCS1,FMNL1,WAC,CLCN6,CORO1A,VCL,PLEKHA4,CDK12,KDM3B,RTN4RL2,BRD4,SFSWAP,GRHL3,R3HDM1,POU2F1,ATXN1,TOR1AIP2,VIM,MEF2D,ATP8B2,POLG2,STK10,RAB10,HSD3B7,S100A16,FGFR1,SLC39A14,MSX2,ELP2,ADNP,HNRNPR,ITGA2,H2AFX,ZNF436,INTS9,ZBTB11,RAB30,MAPT,BAG1,CA11,RFX1,KLC4,ARFIP2,RTN4,HIST2H2AB,POGZ,MBNL1,NEDD4,IQGAP2,PTRF,ANXA7,DCTN4,COPS7B,DDX31,RAPGEFL1,NLGN3,S100A14,ZNF710,AMOT,SPTAN1,RPS6KB2,PPP1R9B,PXN,AP4S1,ZFYVE1,ZNF821,CRIM1,C19orf43,FOXN3,AGPAT4,FERMT2,ARHGEF12,ARHGAP32,CACNB1,GPC2,TBX3,BMP4,BRWD3,C6orf223 |
| 3.917e-02 | -3.24 | transition metal ion transmembrane transporter activity | molecular function | GO:0046915 | 36 | 9 | 16491 | 2164 |
SLC39A14,SLC40A1,TRPM2,SLC30A3,ATOX1,SLC39A7,SLC39A1,SLC39A11,SLC30A7 |
| 3.921e-02 | -3.24 | SMID_BREAST_CANCER_BASAL_UP | MSigDB lists | SMID_BREAST_CANCER_BASAL_UP | 615 | 94 | 17758 | 2279 |
DNM3,TNFRSF21,MFGE8,CHAC1,PRKCA,ST3GAL6,PRKD3,ASNS,MMP7,S100A10,MMP14,HYAL1,PAK1IP1,PCOLCE2,MET,SERPINH1,PEG10,TRIP13,PERP,DBN1,DSC3,MALL,PRAME,MPP6,ZNF124,PDK1,NR6A1,UPP1,TSN,COTL1,DKC1,MCM2,ODC1,WARS,CHAF1A,TIMM44,CXADR,MLLT10,PLIN2,GLS,EXO1,TCF7L1,GATA6,ACP1,VASH2,ECHDC1,TMEM158,CEP170,ZNF532,MID1,PTPN14,RBP1,KLHL24,CHST11,AK2,MCM10,STXBP6,RCAN1,IGF2BP2,PHGDH,DDIT4,IGF2BP3,GART,MYC,MCM5,DSG2,MFAP2,FBXO31,CD44,GMDS,DMRT1,ARNTL2,IFRD1,FGF9,PSAT1,SIGMAR1,MYO10,NXN,KLF6,ANGPTL4,FOXC1,SMPDL3B,DKK1,EPRS,PXDN,DSC2,SYNCRIP,FGFBP1,FSCN1,FAT1,DNAH17,CDKAL1,SLC16A1,PDE9A |
| 3.923e-02 | -3.24 | Unfolded Protein Response (UPR) | REACTOME pathways | R-HSA-381119 | 86 | 18 | 8202 | 1117 |
ZBTB17,EXOSC2,ATF4,CUL7,HSPA5,PARN,SERP1,HERPUD1,SEC31A,YIF1A,SRPRB,ASNS,SHC1,EIF2S1,EXOSC4,ATP6V0D1,DDIT3,MBTPS2 |
| 3.923e-02 | -3.24 | cyclin-dependent protein kinase holoenzyme complex | cellular component | GO:0000307 | 26 | 7 | 17570 | 2233 |
BCCIP,CCNL2,CCNT1,CDK4,KDM5A,CDK12,CDK6 |
| 3.924e-02 | -3.24 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | 110 | 21 | 17758 | 2279 |
SKIV2L,USP7,EP400,CHMP2A,CUL7,ATRX,PSPC1,LYRM7,ZNF804A,ELL,NAV1,DNAJC1,SETD5,HIPK2,TMEM219,VAPB,DISP1,USP11,SMYD3,CTC1,RNF114 |
| 3.924e-02 | -3.24 | MARKEY_RB1_CHRONIC_LOF_UP | MSigDB lists | MARKEY_RB1_CHRONIC_LOF_UP | 110 | 21 | 17758 | 2279 |
FADS1,RFC3,EGR1,POLA1,ELOVL6,SLK,WDHD1,SCMH1,SEMA3F,MCM2,FOXP1,TRIM37,LSS,BRCA2,IDI1,VCAN,KLF4,SQLE,ANP32B,ANGPT2,FDFT1 |
| 3.928e-02 | -3.24 | V$P300_01 | MSigDB lists | V$P300_01 | 236 | 40 | 17758 | 2279 |
CA11,SUPT6H,FOXP1,DDIT4,SHC1,SREBF2,ARMC6,INTS7,CACNB2,IKBKB,ARHGAP1,NLGN3,ZMYM2,FBXL19,PRKACB,SRPK2,MAML3,DPF3,PTBP2,SKAP2,CRIM1,PREX1,RFX2,AKAP12,KCNH3,TMEM206,S100A16,FGFR1,NR2F1,RERE,CAMK2D,DDAH2,SYNCRIP,FDPS,TNFRSF1A,CSMD3,FNBP1L,DMTF1,ZMAT3,TNRC6A |
| 3.932e-02 | -3.24 | COPS8 (COP9 signalosome subunit 8) | protein interactions | 10920 | 44 | 11 | 16036 | 2270 |
FBXW4,CUL4A,COPS4,COPS5,COPS3,CUL2,VIM,COPS7B,COPS6,DDIT3,AMBRA1 |
| 3.932e-02 | -3.24 | LAGE3 (L antigen family, member 3) | protein interactions | 8270 | 44 | 11 | 16036 | 2270 |
SEPHS2,PRAME,TOM1L2,MCM5,CUL2,EIF4A2,NUP43,AHCYL1,PDE9A,RNF214,RNF114 |
| 3.932e-02 | -3.24 | PCGF2 (polycomb group ring finger 2) | protein interactions | 7703 | 44 | 11 | 16036 | 2270 |
PHC2,USP7,RBCK1,HIF1A,SCMH1,RNF2,RANGAP1,USP11,ABHD6,RING1,TMPO |
| 3.932e-02 | -3.24 | MED13 (mediator complex subunit 13) | protein interactions | 9969 | 44 | 11 | 16036 | 2270 |
VDR,RANBP2,TRRAP,HIF1A,MED27,MED15,MED13L,MED24,MED18,MED16,ZC3H13 |
| 3.932e-02 | -3.24 | ACTR1A (ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)) | protein interactions | 10121 | 44 | 11 | 16036 | 2270 |
CAD,DCTN3,KPNA3,NUP133,COPS5,DCTN4,SF3A3,MYH9,UBR5,UBC,SF3A1 |
| 3.938e-02 | -3.23 | - | gene3d domains | 1.10.600.10 | 6 | 3 | 9988 | 1398 |
PDSS2,FDPS,FDFT1 |
| 3.938e-02 | -3.23 | - | gene3d domains | 3.90.1290.10 | 6 | 3 | 9988 | 1398 |
DST,EVPL,DSP |
| 3.938e-02 | -3.23 | - | gene3d domains | 3.30.310.10 | 6 | 3 | 9988 | 1398 |
AP1B1,AP4B1,TBPL1 |
| 3.939e-02 | -3.23 | GAGACTG,MIR-452 | MSigDB lists | GAGACTG,MIR-452 | 91 | 18 | 17758 | 2279 |
TCF12,SNX27,VPS37A,UTP15,RSBN1,FAM126B,UBE2K,FOXO3,GIGYF2,DHX57,PLXNB1,PAIP2,SYNCRIP,TAF4,BCAS3,PRICKLE2,CELF1,SLC25A23 |
| 3.941e-02 | -3.23 | positive regulation of mitotic cell cycle | biological process | GO:0045931 | 115 | 22 | 16441 | 2138 |
CUL4A,BRD4,PAFAH1B1,ANKRD17,CDK4,PLRG1,PBX1,SMARCD3,PPP1R1C,PRKCA,PLCB1,ANXA1,DDX3X,ASNS,BRCA2,NSMCE2,ANAPC11,RAD51B,RPS6KB1,RDX,LSM10,DMRT1 |
| 3.953e-02 | -3.23 | regulation of telomere maintenance | biological process | GO:0032204 | 42 | 10 | 16441 | 2138 |
TERF2IP,SLX4,ACD,YLPM1,ATRX,MYC,DKC1,CTC1,PKIB,TERF2 |
| 3.968e-02 | -3.23 | V$MEIS1BHOXA9_01 | MSigDB lists | V$MEIS1BHOXA9_01 | 136 | 25 | 17758 | 2279 |
CYLD,NRAS,TCF3,ZC3H18,ATG12,NECAP1,GBF1,MBNL1,RAB10,IRS1,EIF4ENIF1,ZFHX3,PDLIM1,ADNP,UBR1,CNIH3,COPS3,SAMD11,BUD31,HOXA3,CSMD3,TBL1X,NRP1,NR2F2,AMOT |
| 3.969e-02 | -3.23 | NCOA1 (nuclear receptor coactivator 1) | protein interactions | 8648 | 106 | 22 | 16036 | 2270 |
ASCC1,FOXO1,PPARG,NR6A1,TEAD1,HSPA5,WDHD1,SMARCA4,BRCA1,ARID1A,UBR5,NR2F1,CXADR,SMAD3,VDR,SNW1,SMARCC1,HIF1A,COPS5,ANKRD11,NCOR1,CARM1 |
| 3.979e-02 | -3.22 | Azathioprine Action Pathway | SMPDB pathways | SMP00427 | 47 | 12 | 978 | 148 |
HPRT1,GART,ABCC4,ENTPD5,ITPA,PPAT,PDE10A,ATIC,ADSL,APRT,SLC29A1,ADK |
| 3.979e-02 | -3.22 | Mercaptopurine Action Pathway | SMPDB pathways | SMP00428 | 47 | 12 | 978 | 148 |
HPRT1,GART,ENTPD5,ABCC4,PPAT,ITPA,PDE10A,ATIC,ADSL,APRT,SLC29A1,ADK |
| 3.979e-02 | -3.22 | Thioguanine Action Pathway | SMPDB pathways | SMP00430 | 47 | 12 | 978 | 148 |
HPRT1,GART,ABCC4,ENTPD5,ITPA,PPAT,PDE10A,ATIC,ADSL,APRT,SLC29A1,ADK |
| 3.980e-02 | -3.22 | skin-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-head_neck-carcinoma-squamous_cell_carcinoma | 14911 | 1940 | 17775 | 2278 |
ARHGAP26,GGT1,ADAM19,CDCP1,THOC5,DPH1,ACTG1,CNTNAP3,DCP1B,AARS2,MRPL10,NAT10,MKS1,TUBE1,SBF2,CCNL2,HMOX2,ABHD6,LPAR3,CIAPIN1,SKI,ZNF37A,PDZD2,MMP7,IKZF5,ZFHX3,THAP4,LETM2,AP1M1,MAD1L1,KDM5C,MSANTD2,SRRM2,PPM1K,CCDC57,HMBOX1,NRAS,KLHL23,RNMT,LIMA1,EHMT1,AP4B1,NFIA,KIF15,C11orf80,C5AR1,WDHD1,ABCC2,SLC9A5,ZNF197,PYCR1,SLC7A1,AHNAK,LRRC40,BDH2,DIRAS1,RIOK1,RUNX1,TPM1,VASH2,SLC25A26,ZNF532,P2RY11,BANP,EPM2AIP1,TMEM63C,FAM189B,TRIO,PIK3R4,BTBD9,PARN,CDC73,PITPNM1,RSPRY1,CHN1,RBM20,UBE3A,CNST,DHX37,APLF,MED24,WDR60,GEMIN4,CCDC88C,PABPC1,PPA1,SAMD3,ANGPT2,MYB,NOM1,RABEPK,LRRC20,KLRD1,GATAD2B,ZNF675,IFRD1,STAG1,ALG6,WDR61,KCNQ3,ZNF587,ARID5B,TYW1,IDH3G,ATAT1,USP10,MAP7D1,ST6GALNAC3,SNAP25,ARRDC4,TRIM37,SRA1,USP46,RDH11,IRS1,DYNC1H1,TSR1,C2orf82,GSTO2,NME7,PDLIM1,EHMT2,TRAP1,FGFBP1,BPNT1,KIAA0196,PDLIM5,ARHGAP10,SGSM3,GALE,SDSL,RAB11FIP4,GTF2H2C,PAFAH1B1,C16orf45,MAB21L3,VTI1A,DDR2,CD99L2,FAM122B,ISG20L2,GRINA,NUP43,ST3GAL6,LCLAT1,MCM9,RPGRIP1L,ZBED2,CD96,ESAM,SPG21,ACD,TBC1D22A,SETD5,WAC,CLCN6,MMP14,C16orf58,INTS12,MSH4,PEG10,MGLL,TRMT12,ZC3H3,DENND1A,LYST,PMS1,KMT2D,ZNF480,SLCO6A1,FAM171A2,PCNXL2,CCNDBP1,MEF2D,KCNH3,GSTCD,NUDT15,DSP,VPS53,MAT2A,SLC39A14,ZFAND3,FBXL5,ARHGAP21,ELP2,KDM4B,ASTN2,METTL6,ARL13B,POLR3E,CAMKMT,HOXA3,RPS6KB1,CENPBD1,CEP170,METTL2B,CATSPERG,BAG1,MAPT,RAB30,MORC2,COMMD10,SHQ1,XRRA1,ATG2B,IP6K2,TRIM22,RNASEH2B,ZNF691,PSMF1,TTLL11,SNW1,POLR3D,PSMG4,TAF3,UNC13A,ACOT11,ANXA5,LTN1,RAPGEFL1,ZNF710,FBXL19,ACTR3B,C15orf41,SAMD4A,RPL22L1,SPTAN1,TTPAL,VPS37A,DDX24,ZC4H2,ZC3H18,NXN,RSBN1,CCDC113,PPIP5K2,UBC,CCDC150,ANXA1,NSD1,SRCAP,HERC1,ACOX1,AEN,BMP4,SORCS2,MTMR1,GPATCH4,CYP24A1,CUL7,RBM33,TRIM16,WDR13,SLC25A21,FAM13A,NLE1,SCAF8,FRRS1,MAP2K3,AMPD3,ECM1,SRSF2,COPS4,NCKIPSD,ANKRD11,HKR1,METTL8,TRIML2,ZNF3,ZMYM2,SLC25A23,FAM184A,VPS13B,DBN1,DSC3,FMNL3,RBCK1,ATF4,MIOS,PPARG,CDK4,ANK2,TSN,LAMA2,KCNH2,KRTCAP2,ODC1,DLST,CRYBG3,LSG1,CXADR,BSN,DYRK1B,TCF7L1,LSS,INSIG1,CHD3,E2F4,AHNAK2,DPP4,C3orf35,ADAM9,PPP3CC,MAGI1,BEND6,USP15,CTU2,FOXO1,CLK1,PRSS3,NKD2,SMAD7,LAMTOR3,MAPK8IP3,FAN1,ZIC2,C1orf52,ARID1B,SPIRE1,RNFT2,ZNF358,CEP290,VPS72,NDRG4,VAPB,CTR9,WNT16,PNPLA3,LRSAM1,CWF19L2,SNX29,WARS2,IFT43,USP49,SETD2,HAUS6,OBSCN,MAPK1IP1L,METTL22,CYB5B,ACOXL,TCF7L2,TBC1D2,PRPF40B,GRIK4,TTC38,SNX24,CASS4,SIL1,DTD1,GGT7,DDX10,SH3PXD2A,USP7,MPI,SART1,OLFM2,PAPD4,UPK3B,ARID2,SLC48A1,OSBPL9,NTSR1,SLC2A1,RPS29,RIPK1,SSBP2,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF121,PAG1,DDX60L,URB1,FDX1,PLXNB1,ANKRD13A,ZNF608,NRF1,IDI1,JAG1,NUP133,GRIN2C,FGGY,ANKRD24,CCDC40,MYH15,BCAP29,AHCYL1,IPO11,PRPF19,KDM3B,SOBP,ARHGAP17,AKAP8L,SSFA2,TEX19,KIRREL2,RAB7A,VIM,CA5B,NHSL1,EIF3H,ZNF251,TJAP1,EXO1,LMBR1L,KLF4,ATG7,MED20,EIF2B3,MUTYH,PARD3,ZNF507,DMGDH,HM13,ESCO1,AUH,RFX1,APRT,VARS,RBM19,POGZ,SLC25A20,ADH5,TTC1,TMEM161A,POLR1B,CPNE7,C12orf4,AP4S1,LRRIQ1,MON1A,FOXN3,SMARCAD1,C22orf34,ABCF2,KRTCAP3,TOP3A,FERMT2,ARHGEF12,RANGAP1,YIPF3,PALLD,EXOG,C8orf33,SMPDL3B,POLR3A,DKK1,CDH24,CACNB1,NOL10,DSC2,L3MBTL3,TAF4,TBX3,CSRNP1,BCAS3,USP20,TMEM219,RBM26,ZNF32,RBPJ,TAF12,NR2F2,XPO6,KIF1B,C6orf223,LMBRD2,ZNF292,CUL4A,LUZP1,PRKCSH,GYG1,PRKCA,NBEAL1,GABPB2,LPIN1,EXOC1,S100A10,ZFYVE28,SUCLG2,CHD2,SPAG6,CSGALNACT2,ZNF646,ACADS,GDAP1,FAM127A,OSBP2,C2orf76,VSNL1,EFHC1,CAMSAP2,ZDHHC14,SON,DENND4A,DDX60,CLNS1A,TMEM206,PLCXD2,GZF1,GNAI1,OSBPL1A,SPOP,DOT1L,DDAH2,TRRAP,SH3RF1,LSM14A,CCNT1,NSMCE1,HSPBAP1,ARL6IP5,LUC7L3,HIC2,XPNPEP1,NRP1,TNFRSF10D,WDR66,BLMH,SPOCK3,SPOCK2,NMD3,PRPF38B,C9orf78,JUP,LARS2,PRPF31,ST6GAL1,DLGAP4,CENPB,TATDN3,DPM3,PRPF39,SSR4,C1orf50,NDUFS7,MTUS1,FAM192A,TECTA,HR,SLC7A11,NOVA2,LDOC1L,USPL1,SCAF1,MYC,PIGG,CNOT4,RTFDC1,FDFT1,EXOSC2,IFNGR2,RREB1,PRIM2,PCCA,RAPGEF4,RDH10,RAP1GAP2,RAP1B,ARID1A,TPRA1,EHBP1,ANGPTL4,SLC26A11,MTR,ATP9B,CAT,ASCC3,C6orf141,MTHFD2,HIF1A,VCAN,SPEN,SRP68,MED15,BIVM,ZCCHC6,SQLE,DPEP1,C7orf50,NCOR1,CNDP2,DHCR7,SMYD3,CPT1C,HS2ST1,VMA21,SYT17,BIRC6,UROD,KIAA0232,TMEM104,PTPRG,CORO6,PABPC1L,HNRNPA3,FLNB,IGSF1,RING1,NOP56,DECR1,SLX4,ASNS,ARMC6,PPID,LPIN2,SOCS6,DTNBP1,TTC3,CMPK1,CDK12,CASP8AP2,GON4L,C1orf228,PREX1,LRRC8A,GNL1,SATB2,MARCH6,MEGF11,SETD7,ERC1,HSD3B7,BAZ1A,MSX2,DNTTIP1,CAMK2D,SMARCC1,WDR5B,DCXR,G6PD,MBTD1,LARGE,FTSJ1,IFT140,SLC4A7,TRAF3,TBXA2R,XRCC4,MID1,SSH2,NOSTRIN,BRAF,B4GALT5,FARS2,KIF5C,DNAJC22,OPA1,GIGYF2,FAM8A1,SFR1,ABL1,ATXN7L1,NEBL,ELP5,SDCBP2,DYNC2H1,CELF1,ERRFI1,MS4A15,NAV3,CLK2,TMC7,FER1L5,SLC40A1,PXN,TTLL5,PSAT1,ZFYVE1,AGPAT4,ADSL,PACS1,BMS1,GUF1,SLC23A2,ZFP62,INF2,RETSAT,DDX50,IREB2,ZNF155,COQ9,ORC5,ATM,SVIL,APAF1,NDUFS5,ADK,DDIT3,IPO4,IMMP2L,PIGM,ZNF76,LETM1,ATRX,RARS2,SLC52A3,PPIL1,SLC30A7,PCYOX1L,DST,CNIH3,JAZF1,ANAPC11,SLC39A7,MYH3,ZEB1,GPATCH1,B3GNTL1,KIAA0922,SLC35C2,HCFC2,YARS,CARM1,CEP128,SRPK2,DTNB,DEAF1,TNK2,FBXW4,SESN2,SKAP2,ZNF195,SIRT6,ITPA,ARRDC3,TFPI,VWCE,MINA,KSR2,MTHFD1L,SGK2,KMT2C,ST3GAL5,ARPC3,YTHDF2,TIMM44,CCDC3,EIF4ENIF1,HLCS,CC2D1B,FAM114A2,CTAGE5,CSMD3,CLU,EME1,ZC3H8,DCAF5,DCTN3,FBXO45,RHOBTB1,ZCCHC8,VTA1,STXBP6,PCSK7,SMG7,QSER1,EVPL,NAMPT,RNF141,ELL,HVCN1,ZNF354A,WDR27,ISPD,ZCCHC7,PRF1,LRP3,AKAP11,HSD17B14,ZNF629,MTHFD1,ZNF234,HBG2,PPAT,ELOVL6,TRA2A,XPO5,ELP3,JMJD1C,ZBED4,ZFP14,LIG4,EIF2A,CORIN,SYT1,AGAP1,HERPUD1,UBE2E1,EXOC6,POP1,SYCP2L,APBB3,BICD1,FSCN1,KIAA0355,KIAA0754,FAT1,FDPS,TMEM117,SLC16A1,TBL1X,IFITM2,TBCK,FNBP1L,PDE9A,N4BP2L2,NR2C2AP,DMXL2,TCF12,CHMP2A,PSTPIP2,TMEM183A,TNXB,PIGH,SMARCA4,COBLL1,TBCCD1,TMEM177,SPATS2,ARSJ,PIBF1,DHX35,SBDS,RIOK2,ZC3H13,RRN3,KCTD11,MPHOSPH10,SOCS1,NVL,PPFIBP1,CBR4,SNTG2,ADCK4,ITGAX,VCL,TMEM120B,C6orf89,AUP1,MAML3,NARS2,NPW,RTN4RL2,ANTXR2,PRAME,METTL2A,GRHL3,ATXN1,POU2F1,MRRF,EDEM2,UBR4,S100A16,BATF3,ARMC4,ALAD,KPNA3,DUS3L,IKZF4,HNRNPR,ZNF557,CEBPZ,ARNTL,FKBP5,TMEM101,NFRKB,ARC,RNF130,BRD9,SMG1,TMEM33,TMCC1,DNAJC2,BCKDK,SUPT6H,ARL15,DYM,KLC4,CMTM8,PDE4B,VPS45,WDR26,ATF7IP,IGF2BP2,MED18,SEMA3E,SOGA1,ENOX1,PIP4K2A,BMP6,GFM2,FAM49A,MFHAS1,PEX7,SCN1B,SEC24C,DCTN4,STC2,TMEM99,LDLRAD3,FBL,ERI3,PKNOX1,MICAL3,TOP1,RPS6KB2,KDM6B,SLC6A16,ARNTL2,DNMBP,CRIM1,PSPC1,KDM5A,SULT4A1,SCFD2,ASAP3,SCMH1,ZNF324B,PDE2A,EIF5B,TMEM187,NAALADL2,ZNF221,CTIF,DAGLB,GADD45A,WDR35,AGTPBP1,ANKRD30BL,VPS37B,POLR1C,NFKBIB,ZSWIM6,NIT1,GNB3,ASCC1,WDR74,CACNA1H,CSPP1,HLTF,CHAC1,NUP160,SYNJ1,PABPC4,AMBRA1,NOS1AP,TOM1L1,PCDH7,C1orf159,SREBF2,NEK6,NSRP1,SYN2,PMAIP1,FAAH2,RABGAP1L,RASSF3,C12orf76,PDS5B,WIZ,ZNF148,FNIP2,LYRM5,HRG,FXN,AVEN,CNTNAP3B,CDK6,WLS,PTPRM,GNL3,PACRGL,RFX2,MSRB3,AKAP12,PLEKHM3,MCL1,C10orf76,RBM28,STOML2,DDX3X,BRCA2,ZNF266,TMEM139,FIS1,RBP1,MEF2C,TNNC1,HERC2,CARS,EP400,CLDN15,TRIP6,KHDRBS1,SIRT7,NHS,RSF1,KCNJ14,CLINT1,SLC1A1,YARS2,ABCA7,SLC39A11,SH2B3,DDX56,C6orf48,KIAA1671,SLC38A5,INTS7,MCM5,CACNB2,ALKBH8,ZNF326,NOC3L,PRMT5,CALN1,COQ3,AGL,MAP3K12,ZNF518B,TOMM34,FMNL2,SERBP1,HMGCR,FADS1,BDNF,COL17A1,RB1CC1,MYO10,PRDM16,EIF4A2,EPS15L1,STPG1,ZNF512B,RYR2,SMARCD3,IMPDH2,CPT1A,ONECUT2,MBNL2,EVI5,ABCF1,ZNF655,NCDN,VPS13C,LRP1B,TASP1,CLASRP,LEMD3,ZNF160,GPN1,CNOT6,WDR33,MB21D2,COG5,SPRED2,ABCA3,ZNF516,DNM3,TRERF1,DDX18,ATP6V1A,NPAS2,ACTR3,PDK4,MYH9,TUBB6,SAFB2,EEA1,STAM,RPP30,PRKD3,ABCA12,ERI1,ZKSCAN1,PYCRL,FMNL1,ATRIP,GSTA4,CEP63,MTHFD2L,PERP,GARS,KRT7,STAMBP,FAM111B,ARHGEF10,LGALS1,ADAM32,ATP6V0A1,TTC28,FGFR1,PDE8B,GNG2,TAF2,PES1,IQCH,CDC16,HIPK2,PEMT,WDR7,PAM,FUS,ZBTB11,ANKS1A,LAMA5,YEATS2,TRIM36,LRCH1,SERINC5,ZNF786,INSIG2,XPC,SESTD1,TRAK1,C1orf226,SF3A3,WDR37,JMJD6,AKT1S1,TGFB2,RSRC1,MBNL1,POM121,KRI1,TADA3,NPRL2,SUV39H2,GATC,PVRL3,ACAP3,ARHGAP1,LYPLA2,HNRNPM,SOX6,ULBP1,DIS3L2,DDHD1,C21orf58,FAM98A,FGF9,ERICH1,POLK,CLYBL,ARHGAP39,FRA10AC1,R3HDM2,FAM126B,ZNF467,UBE2K,PDE3B,DDX49,CASC1,RPA1,KISS1R,ETFDH,RARS,TOE1,BAZ2B,PXDN,NME1-NME2,POLE2,ARID3B,PLPPR2,SLCO5A1,SLC25A19,PTPN4,PSAP,GPAM,IGBP1,DOCK6,CORO2B,KDM4C,ANAPC4,SRM,BCAS4,FAM227A,GPBP1L1,POLR1A,TFIP11,PPARGC1B,MFGE8,HECTD3,CSNK2A1,RNF43,TTI1,TMEM132A,SEC16A,COX10,GIT2,BIRC2,ABL2,ARHGAP18,DHX33,PHKA1,MARVELD2,TRMU,XRCC2,UBAP2L,ZNF85,ETV1,MPST,SF3A1,PTPRK,CDC37,TMPO,FLNC,CHD9,ZNF124,SLC3A2,GCNT2,ABCC4,HARS,BAZ2A,ZNF414,SKIV2L2,KATNAL1,MED27,GDPD1,NOL6,COL4A3BP,ATG12,BRCA1,FLVCR1,ZNF91,MGST1,CCDC28B,KIF16B,PEX1,GLS,ZNF622,MSRA,TOM1L2,TP53BP1,EEFSEC,PER1,TECPR2,CCDC146,SOCS4,TNFRSF1A,RAD51B,SGSM2,RNF214,CHMP4C,XYLB,SEPHS2,SARS,AOC3,OXNAD1,MCM6,LRRC28,ITPRIP,MEX3A,HES6,TRIM15,BARX2,RLF,DNAH1,DOPEY1,RNF40,KIAA1958,ABCA5,PDE10A,SAMD11,PPIL2,GTF2H1,TIMELESS,SYNJ2,GMDS,ALDH18A1,NT5E,TRAPPC9,CAMKK2,LAMC1,CRADD,TLE3,HOMER2,UTP15,BCS1L,WDR25,RNH1,MEX3B,ZNFX1,SUPT5H,NR2F1,VAC14,PGD,PWP1,NAP1L5,ATXN7,FAM135A,ITPRIPL1,SPAG9,SYNCRIP,PALB2,DNAH17,PPP1R12B,ZNF430,ARHGAP12,HMBS,NAPA,PRKAR2A,TESC,RNF114,KCTD7,NDUFA5,CYLD,LPCAT2,RBFOX2,GPR143,RSL1D1,LPCAT3,ZNF83,PELP1,KDM1A,CAD,METTL16,DUS4L,UBR1,ARMC5,FSIP2,DNAJB6,ZDHHC6,CYB5D1,ZFP37,ETF1,HIBCH,ANO8,CORO1A,AKNAD1,PRMT3,CTC1,CASP10,TMEM200A,KAT8,SEC24A,SKIV2L,WDR36,PCGF3,EVL,NARS,GLTSCR2,THSD4,C1QTNF1,SLC35F2,AKAP13,ENC1,NUP214,ARL5B,USP36,TMEM186,BTBD11,SMAD3,RANBP2,RBBP8,SLC30A3,SIX5,ZNF333,CLEC16A,ABHD3,ITGA2,TSSC1,ZNF436,PRRT3,NFASC,ZNF18,PUS1,ZNF589,PPIL3,AP2S1,PKIB,ATXN7L2,UNC13D,MIF4GD,MAP3K13,FAM46B,C14orf159,MAP1S,ARFIP2,ZNF346,CSNK1A1,RMI1,BZW2,ZNF594,IQGAP2,PTPN2,FAM50A,NDUFV1,SACS,ZNF561,ANXA7,CWC27,IFIT5,PRICKLE2,GREB1,SELT,DDX31,CD44,FBXO31,HSD17B12,FAM71E1,ADAMTSL3,GINS3,ZNF654,TEX14,DHX34,PEAR1,RAP1GDS1,C11orf49,HIST1H4J,GPNMB,RHOT2,CHCHD6,TMEM175,PIK3CB,ARMC3,NEU1,MKX,CENPP,ZRANB3,C20orf196,TMEM237,SRBD1,GPC2,ADAT2,SET,GLG1,MSH3,EIF2S1,DNAJC12,ITGB4,RPS6KC1,MIPOL1,POLB,MYCBP2,CGN,PRKAB2,TNFRSF21,PLRG1,TMEM109,ENAH,ADAMTS6,IKBIP,AARS,UBR5,RAC3,MGA,GIPR,RNF111,VPS52,PAK1IP1,ME1,PRADC1,MEIS3,CEP135,FUT11,SEH1L,TBC1D8,DDN,SLC38A6,DPF3,SETD1B,ENHO,NR6A1,ATG9A,ALDH1L2,NOL8,GNG7,CUX1,TCEB3,SEMA3F,FOXRED1,SH3GL1,SKIL,HSDL2,VPS13D,SEMA3C,GREB1L,DNAH2,CCNB1IP1,FAM118A,ZNF598,SYNPO,PTPN14,EFNB2,WDR75,IFT57,DROSHA,CELSR1,ANKRD17,ZHX3,OPHN1,GTF2IRD1,PID1,CCDC47,TGFBR2,CD226,IGF2BP3,ANXA10,NAV1,PI4KB,ZNF586,TSPAN2,ENTPD5,ASAP1,COPS3,VWDE,SLC16A9,IGF2BP1,SAMD13,GTF3C3,LPCAT1,PRPS1,TERF2,ADARB1,USE1,SCAF11,SIK3,DDX28,SYNGAP1,AOC2,KIAA0586,PTPN12,TTYH2,PLCB1,ARIH2,LYRM7,DAGLA,ZNF425,EPRS,KIDINS220,UBAP1,PMEPA1,SRRD,ZZEF1,D2HGDH,ZBTB12,RIOK3,PURB,PEX13,UMPS,MACROD1,IQSEC2,MAP2K4,RTTN,TBKBP1,PTCD2,AMOTL1,TRPM2,RWDD1,LIN28B,ZBTB37,URB2,RIBC2,HFM1,SPRYD7,NDUFB5,OLA1,C1QTNF7,KLHL18,SPATS2L,TM4SF19,AP1B1,SLC25A44,FOSL2,LTB4R,TRIM66,PDE3A,PAIP2,PHC2,CHD7,FLAD1,TERF2IP,ZNF827,PUS3,TMEM184A,SHC1,KDM2A,UCHL5,GLYR1,VGF,NBEA,PNPLA4,SERPINH1,KMT2A,PLEKHA4,ATP6AP1L,ZCCHC14,RFC4,MPP6,RFC3,PDK1,SFXN4,WDPCP,DLG4,KIAA1586,PNN,MED16,GALK2,TBC1D16,POLG2,STK10,DHX57,CPED1,DCBLD2,VDR,HTR7,YIPF2,DNAJA3,ZNF236,ACP1,ALKBH1,ANXA2,MDN1,KLHDC4,PDCD11,NOLC1,TROVE2,NCOR2,SCAMP3,CA11,UTP14A,TTC27,C10orf2,TCF3,NFX1,SLC25A12,RTN4,MON2,LIAS,MLH1,IKBKAP,GDPD5,FOXO3,TMCO6,NEDD4,MAD2L2,ZNF239,ZNF483,DCTPP1,COMMD9,RGS17,PTRF,LRP2BP,NISCH,PMPCA,HARS2,UPF2,COPS7B,RDX,NLGN3,EXOSC4,LARP4B,NT5M,PLEKHG4,MBTPS2,FAM120B,TSHZ1,PFKFB4,WDFY3,FZD3,KCNMA1,WDR18,TBRG4,APTX,OASL,MMAA,NOP58,ECH1,YIF1A,KLHL22,FBXO21,ZDHHC11,HELZ,HNRNPH3,STX18,MYOM2,PGAM5,BRWD3,SLC43A1,LRRC41,SLC37A3,PHF3,FEM1C,UBN1,NF1,KIF5A,PTPRA,FANCD2,TRPM6,ZNF107,PLOD1,RCHY1,ANKRD18A,SIRT2,SLC29A1,BCOR,STK33,CUTC,SNAPC4,AHCYL2,EDC3,MRPS30,SMARCB1,RTN1,ZNF804A,SRPRB,ANAPC1,RAP1A,THADA,YLPM1,LONRF2,ZNHIT6,GPR87,RELB,HYAL1,IPP,JOSD1,PCOLCE2,POLR3B,SLC27A5,NDUFA6,TRIM14,PRKACB,TRIP13,LONP1,TIMM50,LAMA4,ZBTB17,GPM6A,TRIM13,ZNF680,SLC38A1,CMIP,LVRN,GPCPD1,CAV1,ZSCAN2,TCTN1,SERGEF,CDHR3,CHAF1A,UBTF,TMEM132B,RHOU,GEMIN5,PAF1,EPN2,SUFU,GATA6,TRMT5,DNAJC1,RLTPR,MKL2,ABCC3,GALNT10,COPS6,TNRC6A,VIPR1,SLC12A7,AK2,PIGN,CHST11,FN1,SEC24D,TAF1,DPF2,PAX2,ALG8,MED13L,XPO7,C11orf54,PHGDH,CMTM3,RHBDD1,ETFB,DDIT4,CEP164,TOX4,SIPA1L3,MCAM,ATXN2,SEMA3D,CCDC112,NRIP1,N4BP2,CPSF3L,VOPP1,RANBP6,KRT20,PDE4A,TSTA3,TBXAS1,WBSCR22,WWC1,C11orf65,ZSCAN16-AS1,PRDM1,DNAH14,UBAP2,ATAD5,MYBBP1A,EP400NL,INTS5,SDCCAG8,EXOC4,HK2,KIAA1328,ZFP90,TMEM182,PDSS2,C12orf45,C7orf26,ZBTB24,ZNF706,ASH1L,PCNT,CELSR3,SLC5A5,MMRN2,MYO7A,ST7L,SLC9B2,UBTD2,GBF1,SLC39A1,ZSCAN5A,VPS18,FARSA,BRE,LYPLAL1,CAMTA2,CCDC50,RPS6KL1,SLC38A2,ZNF142,MET,CPSF3,TSPAN14,TMEM14C,HTRA2,MOSPD1,TMLHE,HN1,ACSL5,PHLDB2,COL5A2,FAM172A,PTBP2,TFCP2,SFSWAP,PARP2,NLN,R3HDM1,TOR1AIP2,ATP8B2,C1orf174,PUSL1,RAB10,TPK1,WARS,RAD54B,PLIN2,ZC3H12A,HYAL3,ADNP,COPS5,SRFBP1,SLC25A11,SCARB1,DISP1,HEATR1,USP11,TSPAN5,KLHL24,YDJC,TNIK,DNAJA4,SULT1C2,SH2D3A,C17orf80,DBF4,NSUN6,H2AFJ,CLSTN2,LETMD1,CCDC7,PPP1R1C,MFSD10,HDDC2,SFI1,MAN1A1,IL17RE,PRKCH,GART,CTNNBL1,HAS3,DSG2,TANK,KDELC1,SHMT2,TTC17,AMOT,DMRT1,SLC25A1,PAQR6,MSX1,TEAD1,ANKMY2,PSMC3IP,PPP1R21,MARS,PHACTR2,ARHGAP32,MEN1,LENG8,ZNF407,NAPEPLD,SYMPK,TARS,MFN2,RERE,ZNF708,ALG5,ZNF330,CUL2,NCBP2,ZRANB2,MBD6,PREPL,MMP16,ZAK,ARHGAP27,SLC16A10,HRH1 |
| 3.985e-02 | -3.22 | - | gene3d domains | 3.30.1370.50 | 10 | 4 | 9988 | 1398 |
R3HDM1,NFX1,R3HDM2,PARN |
| 3.987e-02 | -3.22 | GSE22886_DC_VS_MONOCYTE_DN | MSigDB lists | GSE22886_DC_VS_MONOCYTE_DN | 189 | 33 | 17758 | 2279 |
ARHGAP26,MYCBP2,PID1,CSTA,RPS6KA5,MAP2K3,PTPN2,PMAIP1,CORO1A,KIAA0922,CCDC88C,OGG1,LYST,USE1,SIK3,CAMKK2,GLTSCR2,RAP1GAP2,MCL1,IL6R,AKAP13,KLF6,NUP214,STK10,TCF7L2,AGTPBP1,VCAN,KLF4,CFD,IFITM2,PTP4A2,TESC,N4BP2L2 |
| 3.987e-02 | -3.22 | GSE17721_LPS_VS_PAM3CSK4_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_24H_BMDM_DN | 189 | 33 | 17758 | 2279 |
SLC12A7,LUZP1,ST6GAL1,ACTR3,MYO7A,NDUFB5,CHCHD10,CLINT1,PAG1,ABL1,KCTD11,MMP7,SREBF2,ZFHX3,TSPAN14,HSD17B12,PTPRK,HMGCR,MTHFD1,PEA15,ANAPC13,CLYBL,RAB7A,LGALS1,PSMG1,MAT2A,MGAT2,GNG2,LSS,SVIL,ADAM9,BLMH,SPOCK2 |
| 3.987e-02 | -3.22 | GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_DN | MSigDB lists | GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_DN | 189 | 33 | 17758 | 2279 |
SEPHS2,RAB11FIP4,TRIP6,TRIM16,SEC24D,TRPM6,RTN4,RPAIN,SEMA6A,SLC39A1,TMCO6,SKI,RGS17,SYN2,SHMT2,ZNRD1,PRMT3,RPS6KB2,SETD1B,TSTA3,TOP3A,PLEKHM3,PRDM1,TRAPPC6B,SAP30BP,WARS,YIPF2,TIMM17A,SDCCAG8,TSSC1,WDR33,USP11,RNF214 |
| 3.987e-02 | -3.22 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDM_UP | 189 | 33 | 17758 | 2279 |
SEPHS2,SRM,CLDN15,TCF3,SIRT2,SLC6A8,KCNJ14,PTRF,GATC,FMNL1,BUD31,COPS7B,TMEM120B,SERBP1,PCSK6,SPTAN1,LRRC20,PEA15,ARHGEF12,TPRA1,EVI5,STK10,HLA-DMA,FSCN1,SIX5,CDK9,TBX3,SQLE,RPS6KB1,POLR1C,IFITM2,BLMH,RAB30 |
| 3.987e-02 | -3.22 | GSE17721_PAM3CSK4_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_8H_BMDM_DN | 189 | 33 | 17758 | 2279 |
FAM208B,ANKRD17,PCSK7,UBL5,TOX4,FKBP1A,PEX7,DNAJB6,MBD2,CBR4,UPF2,SELT,TLCD1,DDHD1,SLC40A1,GCNT2,TRA2A,RAP1B,RSBN1,BRCA1,KLF6,POLR3A,UBC,WARS,SPOP,ZFP62,TNFRSF1A,RNF138,PEX13,XPO6,RNF214,RNF114,STK4 |
| 3.987e-02 | -3.22 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | 189 | 33 | 17758 | 2279 |
ZNF516,ARFIP2,KIF5C,CCDC47,RLF,FAM8A1,NUBPL,GTF3C3,FUT11,LONP1,NIPSNAP1,SKAP2,CLYBL,PCCA,AGPAT4,TFPI,ELP3,SLC35G1,METTL15,RSBN1,EIF2A,CHCHD6,PLCXD2,FAM135A,FAM114A2,HIPK2,GLG1,ADAM9,PEX13,MYOM2,CLU,RBPJ,RBP1 |
| 3.987e-02 | -3.22 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | 189 | 33 | 17758 | 2279 |
ADAM19,MCM10,C16orf45,IP6K2,PHGDH,CD226,CDC73,ZBED2,KDELC1,PPCDC,METTL8,CTR9,COQ3,MPST,TMPO,RFC3,LGALS1,TPM4,WDHD1,RAP1GDS1,BRCA1,DKC1,NR2F1,SLC39A14,HPRT1,TRIB3,NME7,H2AFX,DPP4,GPN1,DNAJC12,BBIP1,BMI1 |
| 3.987e-02 | -3.22 | GSE14308_TH2_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_TH2_VS_NATURAL_TREG_DN | 189 | 33 | 17758 | 2279 |
UNC13D,HERC2,VIPR1,USP7,MYCBP2,PPP2R2A,HES6,SMARCA4,OPA1,PABPC1L,SNAPC4,PITPNM1,MCM9,EDC3,CEP164,KIAA1958,UBR1,SERPINH1,FUT11,HTRA2,FMNL3,PPP1R21,GNG7,PREX1,CAMSAP2,ZSCAN2,ATXN7,HSPBAP1,DHCR7,BRD9,CATSPERG,TSPAN5,ZNF598 |
| 3.989e-02 | -3.22 | GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN | MSigDB lists | GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN | 169 | 30 | 17758 | 2279 |
SLC38A6,MYCBP2,SERINC5,AUH,PTBP2,FAM172A,KCNQ3,FAM46B,ZNF107,NFX1,TMEM123,QSER1,SSBP2,SEC16A,PEX7,KDM2A,FAM206A,WDR27,LARGE,GEMIN4,CEP135,NRIP1,ZMYM2,XRCC4,N4BP2,ACTR3B,SNX29,C12orf4,FAM184A,ZSWIM6 |
| 3.989e-02 | -3.22 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | 169 | 30 | 17758 | 2279 |
VIPR1,PTP4A1,CHD9,IL11RA,PCNT,ITPRIP,TSPYL4,PTPRM,ARRDC3,RAP1GAP2,CUX1,PDE4B,MEF2D,SOX4,ENC1,TIGD1,ST3GAL5,FAM8A1,SLC26A11,ANXA1,SKIL,FBXL5,ARHGAP21,ZDHHC11,CNST,GADD45A,DPEP1,SOX6,SNX29,KAT6A |
| 3.995e-02 | -3.22 | negative regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001243 | 90 | 18 | 16441 | 2138 |
MCL1,GRINA,OPA1,NOL3,HSPA1A,HERPUD1,KDM1A,TAF9B,DDX3X,RRN3,HIF1A,TRAP1,TMEM161A,TRIAP1,CLU,CD44,YBX3,HTRA2 |
| 3.998e-02 | -3.22 | HSPA9 (heat shock 70kDa protein 9 (mortalin)) | protein interactions | 3313 | 184 | 35 | 16036 | 2270 |
CUL7,DNAJA4,BRAF,CUL4A,FN1,CCDC58,SIRT7,HSD17B10,BZW2,SHC1,ZSWIM7,ATG3,SHMT2,VCL,RPS6KB2,GINS3,ITPA,RAB7A,LDHA,RAP1GDS1,FERMT2,TIMM44,AHNAK,GTF2A1,DNAJC1,DNAJA3,COPS5,G6PD,CUL2,H2AFX,TBPL1,GPN1,FUS,COPS6,AGO3 |
| 4.004e-02 | -3.22 | PTPase_domain | interpro domains | IPR000242 | 37 | 9 | 18293 | 2341 |
PTPN2,PTPRA,PTPRM,PTPN4,PTPN12,PTP4A2,PTPRG,PTPN14,PTPRK |
| 4.006e-02 | -3.22 | bone-pelvis-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-pelvis-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 674 | 102 | 17775 | 2278 |
FEZ2,SYT17,PHF3,ATP6V1A,CELSR3,PSTPIP2,CACNA1H,CHAC1,PTPRG,RADIL,LPIN1,MGA,CAD,ANAPC1,PDZD2,NUP133,UBR1,WAC,MYH15,CEP63,PCOLCE2,FUT11,DEAF1,PTPRM,ANK2,EHMT1,VWCE,PCNXL2,AKAP12,KIAA1586,SON,STK10,SERGEF,PDE8B,GZF1,CHAF1A,TRRAP,SUPT4H1,ZNF266,HSPBAP1,ZNF236,ABCC3,USP11,SETD6,LAMA5,ZNF589,PRPF38B,AOC3,SSH2,BRAF,PIGN,CLK1,KHDRBS1,DPF2,TRIO,NSUN6,OPHN1,RTN4,VARS,RBM19,PHGDH,RSRC1,ARID1B,MFHAS1,NEDD4,IQGAP2,DOPEY1,POLR3D,KIAA1958,CNST,CEP290,SCAF1,CACNB2,GREB1,NRIP1,MTHFD1,HMGCR,RREB1,GINS3,PSPC1,SETD2,TEX14,OBSCN,LENG8,PALLD,EHBP1,CHCHD6,MYBBP1A,NME7,EHMT2,TRAP1,KIAA0355,HERC1,VCAN,ZNF330,FAT1,BCAS3,ZCCHC6,NCOR1,WDR33,ITGB4,PRKAR2A |
| 4.010e-02 | -3.22 | EIF2S2 (eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa) | protein interactions | 8894 | 66 | 15 | 16036 | 2270 |
DDX56,SUB1,H2AFX,EIF2S1,CSNK2A1,ETF1,RNF2,CEP126,FBL,EIF2B3,ZCCHC7,NOP58,RPA1,NOP56,RPS6KB2 |
| 4.016e-02 | -3.21 | embryonic skeletal system development | biological process | GO:0048706 | 128 | 24 | 16441 | 2138 |
DEAF1,FGF9,CHST11,SETD2,RDH10,MKS1,PBX1,SATB2,MTHFD1L,SLC35D1,TGFBR2,FLVCR1,SLC39A1,SMAD3,MBTD1,MMP14,HOXA3,ZEB1,HYAL1,DLX2,BMP4,MMP16,MTHFD1,MEF2C |
| 4.019e-02 | -3.21 | HAX1 (HCLS1 associated protein X-1) | protein interactions | 10456 | 112 | 23 | 16036 | 2270 |
GPM6A,CUL4A,ABCC4,ANK2,HSPA5,VSNL1,HIST1H2BL,SYT1,UBC,RPA1,SNCA,IQGAP2,GNG2,SHC1,STX1A,SYN2,NDRG4,SVIL,PPP3CC,CLU,ZNRD1,HTRA2,MAPT |
| 4.019e-02 | -3.21 | CREB1 (cAMP responsive element binding protein 1) | protein interactions | 1385 | 112 | 23 | 16036 | 2270 |
DEAF1,POU2F1,SMARCA4,ATF7IP,VIM,HDAC8,BRCA1,TRIM22,RPS6KA5,SRA1,POGZ,TOX4,ABL1,GTF2A1,SREBF2,CHD3,TAF4,ZNF436,ATM,RNF111,NCOR1,ZMYM2,CARM1 |
| 4.022e-02 | -3.21 | cell cycle checkpoint | biological process | GO:0000075 | 220 | 38 | 16441 | 2138 |
HMGA2,XPC,CSNK2A1,PSMF1,GIGYF2,MAD2L2,ANAPC1,BRE,NEK6,INTS7,WAC,ANAPC11,TRIAP1,ANAPC10,MAD1L1,ATRIP,CEP63,FBXO31,PRPF19,PEA15,CRADD,FOXN3,TEX14,PSMA1,BRCA1,SOX4,UBE2E1,UBC,KLHL22,RBBP8,CDC16,TRRAP,TP53BP1,H2AFX,ATM,BRCC3,ZAK,ANAPC4 |
| 4.035e-02 | -3.21 | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | 37 | 9 | 17775 | 2278 |
BRAF,NRAS,CLCN6,RNF130,BCOR,MET,KIAA1549,FGFR1,GNAI1 |
| 4.043e-02 | -3.21 | RASSF1 (Ras association (RalGDS/AF-6) domain family member 1) | protein interactions | 11186 | 55 | 13 | 16036 | 2270 |
SNX27,CUL4A,ID1,SUV39H2,ITPRIP,TNFRSF1A,MAP1S,ATM,C8orf33,HIST2H2AB,XPO6,KDM1A,STK4 |
| 4.043e-02 | -3.21 | NINL (ninein-like) | protein interactions | 22981 | 55 | 13 | 16036 | 2270 |
SYT17,MCM10,ZFHX3,UTP14A,TSPYL4,KANSL1,RIBC2,CCDC146,TCEB3,MAD1L1,BRCA1,LRSAM1,ZNF646 |
| 4.043e-02 | -3.21 | NUP98 (nucleoporin 98kDa) | protein interactions | 4928 | 55 | 13 | 16036 | 2270 |
PAF1,USP7,CUL7,NUP133,SIRT7,XPO5,NFX1,CSNK2A1,HDAC8,NUP43,CDC73,SEH1L,CDC37 |
| 4.043e-02 | -3.21 | SNX6 (sorting nexin 6) | protein interactions | 58533 | 55 | 13 | 16036 | 2270 |
TNIK,DNM3,GTF2A1,TSN,CAMKMT,ATG7,VAPB,SHMT2,BRCA1,IMPDH2,CCNL2,TGFBR2,USP46 |
| 4.043e-02 | -3.21 | MED15 (mediator complex subunit 15) | protein interactions | 51586 | 55 | 13 | 16036 | 2270 |
SMAD3,TRRAP,HIF1A,SEC24C,MED27,UBAP2L,MED24,ATXN1,MED18,MED16,MED20,IGBP1,ZC3H13 |
| 4.043e-02 | -3.21 | SNRPB2 (small nuclear ribonucleoprotein polypeptide B) | protein interactions | 6629 | 55 | 13 | 16036 | 2270 |
HMBOX1,MCM6,PHF5A,ELP2,LIN28B,PRPF31,SF3A3,PRPF4,RNF2,ZNF346,SRRM2,PNMA1,SF3A1 |
| 4.043e-02 | -3.21 | MRPS22 (mitochondrial ribosomal protein S22) | protein interactions | 56945 | 55 | 13 | 16036 | 2270 |
FAM192A,COPS5,TRA2A,MYC,TMEM126A,MRPS27,SHMT2,TRMT10B,RNF2,ZC3H3,UBC,RPS6KB2,MRPS11 |
| 4.043e-02 | -3.21 | COPS7A (COP9 signalosome subunit 7A) | protein interactions | 50813 | 55 | 13 | 16036 | 2270 |
FBXW4,CUL4A,COPS4,COPS5,COPS3,CUL2,IKBKB,CSNK2A1,COPS7B,COPS6,PRMT5,DDIT3,TOM1L1 |
| 4.045e-02 | -3.21 | V$SREBP1_02 | MSigDB lists | V$SREBP1_02 | 85 | 17 | 17758 | 2279 |
UNC13D,SIK3,NF1,BAZ2A,ZFYVE1,WDR13,DLGAP4,ZFP36L1,TOM1L1,ATXN7L1,SREBF2,HYAL1,CORO1A,C6orf223,ZNF532,SEH1L,MEF2C |
| 4.049e-02 | -3.21 | V$EGR1_01 | MSigDB lists | V$EGR1_01 | 257 | 43 | 17758 | 2279 |
DLL4,EGR1,PAFAH1B1,PPARGC1B,PBX1,RNF24,FAM122B,ISG20L2,RSPRY1,FAM192A,ZNF827,ELL,HR,KDM2A,SREBF2,VGF,RELB,SHF,RAPGEFL1,IGF2BP1,ERRFI1,MGLL,ZMYM2,SLC25A23,LYPLA2,MYB,GPHN,GLTSCR2,ZNF414,TLE3,TPM4,FRA10AC1,AKAP12,ATG12,EHBP1,UBTF,SDCCAG8,TBX3,CSMD3,RUNX1,BRWD3,ANKS1A,MEF2C |
| 4.054e-02 | -3.21 | PAC | interpro domains | IPR001610 | 26 | 7 | 18293 | 2341 |
ARNTL2,KCNH3,KCNH2,HIF1A,NPAS2,PER1,ARNTL |
| 4.057e-02 | -3.20 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902235 | 31 | 8 | 16441 | 2138 |
PTPN2,PMAIP1,GRINA,OPA1,HSPA1A,DDIT3,HERPUD1,SPOP |
| 4.057e-02 | -3.20 | regulation of oligodendrocyte differentiation | biological process | GO:0048713 | 31 | 8 | 16441 | 2138 |
PPARG,NF1,TNFRSF21,ID2,BMP4,DLX2,PRMT5,TCF7L2 |
| 4.058e-02 | -3.20 | Body mass index(PMID:22344221) | GWAS genes | Body mass index(PMID:22344221) | 5 | 3 | 2389 | 419 |
CDKAL1,BDNF,GIPR |
| 4.058e-02 | -3.20 | Normalized brain volume(PMID:19010793) | GWAS genes | Normalized brain volume(PMID:19010793) | 5 | 3 | 2389 | 419 |
SVIL,BICD1,FOXO3 |
| 4.058e-02 | -3.20 | Type 2 diabetes(PMID:19401414) | GWAS genes | Type 2 diabetes(PMID:19401414) | 5 | 3 | 2389 | 419 |
CDKAL1,IGF2BP2,TCF7L2 |
| 4.058e-02 | -3.20 | Two-hour glucose challenge(PMID:20081857) | GWAS genes | Two-hour glucose challenge(PMID:20081857) | 5 | 3 | 2389 | 419 |
VPS13C,TCF7L2,GIPR |
| 4.058e-02 | -3.20 | Height(PMID:22021425) | GWAS genes | Height(PMID:22021425) | 5 | 3 | 2389 | 419 |
SERPINH1,PRKCA,DYM |
| 4.060e-02 | -3.20 | RMDN1 (regulator of microtubule dynamics 1) | protein interactions | 51115 | 6 | 3 | 16036 | 2270 |
SHC1,ECHDC1,H2AFX |
| 4.060e-02 | -3.20 | SIPA1 (signal-induced proliferation-associated 1) | protein interactions | 6494 | 6 | 3 | 16036 | 2270 |
BRD4,FN1,FMNL1 |
| 4.060e-02 | -3.20 | RYR3 (ryanodine receptor 3) | protein interactions | 6263 | 6 | 3 | 16036 | 2270 |
RYR2,FKBP1A,BMI1 |
| 4.060e-02 | -3.20 | UEVLD (UEV and lactate/malate dehyrogenase domains) | protein interactions | 55293 | 6 | 3 | 16036 | 2270 |
LRSAM1,UBC,RNF114 |
| 4.060e-02 | -3.20 | DMBT1 (deleted in malignant brain tumors 1) | protein interactions | 1755 | 6 | 3 | 16036 | 2270 |
ICE2,COPS6,CDK6 |
| 4.060e-02 | -3.20 | VPS54 (vacuolar protein sorting 54 homolog (S. cerevisiae)) | protein interactions | 51542 | 6 | 3 | 16036 | 2270 |
VPS52,VPS53,TSSC1 |
| 4.060e-02 | -3.20 | Ppard (peroxisome proliferator activator receptor delta) | protein interactions | 19015 | 6 | 3 | 16036 | 2270 |
NCOR2,NCOR1,GADD45A |
| 4.060e-02 | -3.20 | Grap2 (GRB2-related adaptor protein 2) | protein interactions | 17444 | 6 | 3 | 16036 | 2270 |
ABL1,SHC1,KHDRBS1 |
| 4.060e-02 | -3.20 | TTC39B (tetratricopeptide repeat domain 39B) | protein interactions | 158219 | 6 | 3 | 16036 | 2270 |
VAPB,PREPL,MTIF2 |
| 4.060e-02 | -3.20 | PAPD5 (PAP associated domain containing 5) | protein interactions | 64282 | 6 | 3 | 16036 | 2270 |
NIFK,ZCCHC7,ZC3H3 |
| 4.060e-02 | -3.20 | IFT46 (intraflagellar transport 46) | protein interactions | 56912 | 6 | 3 | 16036 | 2270 |
IFT81,IFT57,ARL13B |
| 4.060e-02 | -3.20 | WDR75 (WD repeat domain 75) | protein interactions | 84128 | 6 | 3 | 16036 | 2270 |
CUL7,FBL,SIRT7 |
| 4.060e-02 | -3.20 | PSTPIP2 (proline-serine-threonine phosphatase interacting protein 2) | protein interactions | 9050 | 6 | 3 | 16036 | 2270 |
PTPN12,SHC1,PSTPIP2 |
| 4.060e-02 | -3.20 | NDUFAF7 (NADH dehydrogenase (ubiquinone) complex I, assembly factor 7) | protein interactions | 55471 | 6 | 3 | 16036 | 2270 |
FNTB,ST3GAL5,OXLD1 |
| 4.060e-02 | -3.20 | CAPRIN2 (caprin family member 2) | protein interactions | 65981 | 6 | 3 | 16036 | 2270 |
COPS6,FAM8A1,AUP1 |
| 4.060e-02 | -3.20 | STK32C (serine/threonine kinase 32C) | protein interactions | 282974 | 6 | 3 | 16036 | 2270 |
MCM5,FDFT1,CDC37 |
| 4.060e-02 | -3.20 | MYLK4 (myosin light chain kinase family member 4) | protein interactions | 340156 | 6 | 3 | 16036 | 2270 |
SUPT20H,COPS5,CDC37 |
| 4.060e-02 | -3.20 | Mapk14 (mitogen-activated protein kinase 14) | protein interactions | 26416 | 6 | 3 | 16036 | 2270 |
SUPT20H,GADD45A,MAP2K3 |
| 4.060e-02 | -3.20 | ZNF350 (zinc finger protein 350) | protein interactions | 59348 | 6 | 3 | 16036 | 2270 |
ATF7IP,BRCA1,RBBP8 |
| 4.060e-02 | -3.20 | ZNF135 (zinc finger protein 135) | protein interactions | 7694 | 6 | 3 | 16036 | 2270 |
ANXA7,GADD45A,RAP1B |
| 4.060e-02 | -3.20 | BTG3 (BTG family, member 3) | protein interactions | 10950 | 6 | 3 | 16036 | 2270 |
ATXN1,BANP,CUL2 |
| 4.060e-02 | -3.20 | NOL7 (nucleolar protein 7) | protein interactions | 51406 | 6 | 3 | 16036 | 2270 |
RNF2,CUL7,C8orf33 |
| 4.060e-02 | -3.20 | NR6A1 (nuclear receptor subfamily 6, group A, member 1) | protein interactions | 2649 | 6 | 3 | 16036 | 2270 |
NSD1,NCOR1,NR6A1 |
| 4.060e-02 | -3.20 | ANXA8L1 (annexin A8-like 1) | protein interactions | 728113 | 6 | 3 | 16036 | 2270 |
TERF2IP,ACD,UCHL5 |
| 4.060e-02 | -3.20 | HESX1 (HESX homeobox 1) | protein interactions | 8820 | 6 | 3 | 16036 | 2270 |
NCOR1,NPAS2,KDM1A |
| 4.060e-02 | -3.20 | TRPM8 (transient receptor potential cation channel, subfamily M, member 8) | protein interactions | 79054 | 6 | 3 | 16036 | 2270 |
SF3A3,USP10,ZC3H18 |
| 4.063e-02 | -3.20 | HALLMARK_HYPOXIA | MSigDB lists | HALLMARK_HYPOXIA | 196 | 34 | 17758 | 2279 |
KLHL24,ZNF292,KIF5A,SLC2A1,MYH9,JMJD6,BHLHE40,FOSL2,PRKCA,FOXO3,DDIT4,AMPD3,PTRF,STC2,ERRFI1,SLC25A1,SAP30,GCNT2,PDK1,HSPA5,LDHA,AKAP12,CAV1,KLF6,ANGPTL4,PLIN2,PAM,HK2,LARGE,XPNPEP1,ANXA2,SCARB1,RBPJ,DDIT3 |
| 4.063e-02 | -3.20 | V$CEBP_C | MSigDB lists | V$CEBP_C | 196 | 34 | 17758 | 2279 |
SARS,PRDX6,DDR2,NFX1,RLF,FOXP1,FOXO3,MAP2K3,FSIP2,STC2,ETF1,CHD2,ETV1,ACSL5,SCAF11,BDNF,TUBA1A,CRIM1,JMJD1C,KCNMA1,PTPN12,SOX4,DENND4A,MBNL2,ERC1,FKBP3,RERE,SLC39A14,SUPT4H1,AHNAK,ATAD5,IKZF4,PER1,HOXA3 |
| 4.063e-02 | -3.20 | Transport of Mature mRNA Derived from an Intronless Transcript | REACTOME pathways | R-HSA-159231 | 35 | 9 | 8202 | 1117 |
RANBP2,NUP133,NCBP2,NUP43,CPSF3,NUP160,NUP214,SEH1L,POM121 |
| 4.063e-02 | -3.20 | Base Excision Repair | REACTOME pathways | R-HSA-73884 | 35 | 9 | 8202 | 1117 |
RFC4,POLB,RFC3,APEX1,POLE2,PARP2,MUTYH,OGG1,RPA1 |
| 4.063e-02 | -3.20 | Resolution of Abasic Sites (AP sites) | REACTOME pathways | R-HSA-73933 | 35 | 9 | 8202 | 1117 |
RFC4,POLB,RFC3,APEX1,POLE2,PARP2,MUTYH,OGG1,RPA1 |
| 4.067e-02 | -3.20 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN | 37 | 9 | 17758 | 2279 |
DCTN3,DNAJA4,LUZP1,RPL28,UROD,PQBP1,PNPLA4,ZNF91,ARIH2 |
| 4.067e-02 | -3.20 | KYNG_DNA_DAMAGE_BY_4NQO | MSigDB lists | KYNG_DNA_DAMAGE_BY_4NQO | 37 | 9 | 17758 | 2279 |
ID1,IFNGR2,ATOX1,HSPB8,ANKRD11,PCK2,PPA1,TMEM158,ARPC3 |
| 4.067e-02 | -3.20 | NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON | 37 | 9 | 17758 | 2279 |
FLAD1,SCAMP3,SHC1,FAM189B,FDPS,DPM3,KRTCAP2,SLC50A1,CLK2 |
| 4.069e-02 | -3.20 | FILAMIN_REPEAT | prosite domains | PS50194 | 11 | 4 | 11866 | 1504 |
FLNC,MYCBP2,FLNB,KDELC1 |
| 4.069e-02 | -3.20 | MBD | prosite domains | PS50982 | 11 | 4 | 11866 | 1504 |
MBD6,BAZ2B,BAZ2A,MBD2 |
| 4.069e-02 | -3.20 | R3H | prosite domains | PS51061 | 11 | 4 | 11866 | 1504 |
R3HDM1,NFX1,R3HDM2,PARN |
| 4.069e-02 | -3.20 | WH1 | prosite domains | PS50229 | 11 | 4 | 11866 | 1504 |
ENAH,SPRED2,EVL,HOMER2 |
| 4.069e-02 | -3.20 | GBD_FH3 | prosite domains | PS51232 | 11 | 4 | 11866 | 1504 |
INF2,FMNL3,FMNL1,FMNL2 |
| 4.073e-02 | -3.20 | palate development | biological process | GO:0060021 | 84 | 17 | 16441 | 2138 |
TSHZ1,MSX1,INSIG2,PRDM16,ARID5B,WDPCP,SATB2,BCOR,TGFBR2,SKI,CHD7,INSIG1,TBX3,CSRNP1,PAK1IP1,ANP32B,MEF2C |
| 4.073e-02 | -3.20 | telomere maintenance | biological process | GO:0000723 | 84 | 17 | 16441 | 2138 |
RFC4,RFC3,PRIM2,APEX1,POLA1,HIST1H4J,DKC1,TNKS1BP1,RPA1,TERF2IP,SLX4,ACD,POLE2,NSMCE2,ATM,CTC1,TERF2 |
| 4.075e-02 | -3.20 | SMAD1 (SMAD family member 1) | protein interactions | 4086 | 166 | 32 | 16036 | 2270 |
HMGA2,ZNF76,TRIP6,XPC,BTBD2,RFX1,UBXN1,FOXO3,MGA,NEDD4,SKI,ZEB1,MED24,RAN,KDM6B,KMT2D,ELP3,ZNF512B,MEN1,NUP214,UBC,ZNF251,SKIL,SMAD3,HIPK2,LEMD3,CDK9,MKL2,MED15,RUNX1,RAB30,USP15 |
| 4.082e-02 | -3.20 | mixed_carcinoma | COSMIC cancer mutations | mixed_carcinoma | 26 | 7 | 17775 | 2278 |
ATM,RNF43,BRCA2,BRAF,BRCA1,MLH1,MAP2K4 |
| 4.082e-02 | -3.20 | Laminin_EGF | pfam domains | PF00053 | 31 | 8 | 16629 | 2165 |
LAMA4,LAMC1,CELSR1,CELSR3,PEAR1,MEGF11,LAMA2,LAMA5 |
| 4.084e-02 | -3.20 | ENZYME_BINDING | MSigDB lists | ENZYME_BINDING | 176 | 31 | 17758 | 2279 |
DMXL2,TRIP6,CDC42EP2,AKAP8L,MAP3K13,PREX1,MAPK8IP3,ARFIP2,AKAP12,SMG7,BCOR,SIRT2,BRCA1,IL6R,COTL1,SUPT5H,FOXO3,NOS1AP,IRS1,RANBP2,TRIB3,SOCS1,HIF1A,ATG3,VAPB,ADAM9,MAP3K12,PDLIM5,AKAP11,MAPT,SGSM3 |
| 4.084e-02 | -3.20 | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | 176 | 31 | 17758 | 2279 |
HERC2,EVL,BCAS4,FBXW4,RBCK1,TAF1,DDX18,RB1CC1,SFXN4,ZC4H2,ATF7IP2,ZNF107,METTL15,POP5,PRKCA,PHGDH,TTC28,C8orf33,EHBP1,ERC1,TMEM132B,KLHL22,ZFHX3,PPCDC,CDKAL1,LARP4B,ZC3H8,ZNF518B,RABEP1,CASP10,SGSM3 |
| 4.085e-02 | -3.20 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | 347 | 56 | 17758 | 2279 |
DNAJA4,RWDD1,XPC,GPBP1L1,ITFG1,SESTD1,STXBP6,PAX2,MRI1,IP6K2,SPATS2L,POM121,NRF1,LYPLAL1,CACNB2,PPFIBP1,VAPB,SAMD13,MET,GMDS,CDK6,SPAG6,PTPRK,MSI2,CCDC57,NAA38,KRT7,WDFY3,CUX1,NFIA,AKAP12,SCMH1,PHACTR2,SATB2,CYB5B,ODC1,NAPEPLD,FOXC1,ZNF655,TPK1,CXADR,EPN2,IQCH,DNAJC1,ASTN2,FAT1,KLF4,TMEM139,EXOC4,CTAGE5,IFT140,SENP3,PDSS2,KIF1B,DMTF1,HRH1 |
| 4.086e-02 | -3.20 | BSG (basigin (Ok blood group)) | protein interactions | 682 | 124 | 25 | 16036 | 2270 |
SLC3A2,DNM3,LARS2,TBRG4,METTL15,CAV1,XPO7,TTC28,SYMPK,VAC14,VPS53,NOP56,EXOC1,MYBBP1A,INTS5,PPIL2,EXOC4,PDS5B,VPS52,ATM,INTS12,SLC16A1,MDN1,IPO11,COG5 |
| 4.094e-02 | -3.20 | RNA catabolic process | biological process | GO:0006401 | 227 | 39 | 16441 | 2138 |
DROSHA,LIN28B,PAPD4,DCP1B,RPS29,PPP2R2A,SMG7,ZFP36L1,MLH1,RNASEH2B,TNKS1BP1,PARN,PABPC4,EDC3,RPS16,ERI1,UPF2,ETF1,EXOSC4,CNOT4,PABPC1,DIS3L2,SKIV2L,EXOSC2,WDR61,SKIV2L2,EIF4A2,DHX34,RNH1,CTIF,POP1,RPL28,ZCCHC6,ATM,CNOT6,NCBP2,NOCT,SMG1,AGO3 |
| 4.100e-02 | -3.19 | histone H3 acetylation | biological process | GO:0043966 | 48 | 11 | 16441 | 2138 |
TADA3,BRD4,BRCA2,TRIM16,PER1,TCF3,ELP3,TAF12,POLE3,YEATS2,KAT6A |
| 4.107e-02 | -3.19 | TBP (TATA box binding protein) | protein interactions | 6908 | 154 | 30 | 16036 | 2270 |
TCF12,ZNF76,MSX1,ATF4,TAF1,TEAD1,KDM5A,POU2F1,SETD7,MCM2,SNAPC4,POLR2A,TAF9B,MKX,TAF2,UBTF,ATXN7,SUB1,RRN3,COL26A1,GTF2A1,TAF3,MYC,TAF4,TBPL1,ICE2,GTF3C3,TAF12,CPSF3,NFKBIB |
| 4.107e-02 | -3.19 | mismatch repair complex | cellular component | GO:0032300 | 11 | 4 | 17570 | 2233 |
PMS1,MSH4,MLH1,MSH3 |
| 4.107e-02 | -3.19 | CD40 receptor complex | cellular component | GO:0035631 | 11 | 4 | 17570 | 2233 |
TRAF3,BIRC2,HTRA2,IKBKB |
| 4.107e-02 | -3.19 | IkappaB kinase complex | cellular component | GO:0008385 | 11 | 4 | 17570 | 2233 |
MAP3K13,ERC1,DNAJA3,IKBKB |
| 4.107e-02 | -3.19 | MCM complex | cellular component | GO:0042555 | 11 | 4 | 17570 | 2233 |
MCM6,MCM2,MCM5,MCM9 |
| 4.108e-02 | -3.19 | KAUFFMANN_DNA_REPLICATION_GENES | MSigDB lists | KAUFFMANN_DNA_REPLICATION_GENES | 143 | 26 | 17758 | 2279 |
RFC4,POLB,RFC3,MCM6,PRIM2,POLA1,ABCF2,NFIA,LIG4,BRCA1,SUPT5H,MCM2,POLG2,MCM9,CHAF1A,RPA1,MYBBP1A,POLE2,TOM1L2,MCM5,SET,ORC5,SSBP1,POLE3,WDR33,NT5M |
| 4.109e-02 | -3.19 | CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | MSigDB lists | CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | 26 | 7 | 17758 | 2279 |
HIRIP3,HDAC8,ARID1A,RSF1,SUV39H2,SET,CHAF1A |
| 4.109e-02 | -3.19 | NIKOLSKY_BREAST_CANCER_5P15_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_5P15_AMPLICON | 26 | 7 | 17758 | 2279 |
SLC12A7,ZDHHC11,BRD9,LPCAT1,TRIP13,NKD2,MRPL36 |
| 4.109e-02 | -3.19 | CHOW_RASSF1_TARGETS_UP | MSigDB lists | CHOW_RASSF1_TARGETS_UP | 26 | 7 | 17758 | 2279 |
ID2,RFC4,INSIG1,PARP2,MBNL1,MID1,PEX1 |
| 4.113e-02 | -3.19 | MITOCARRIER | prints domains | PR00926 | 27 | 6 | 4759 | 462 |
SLC25A19,SLC25A12,SLC25A44,SLC25A23,SLC25A1,SLC25A21 |
| 4.114e-02 | -3.19 | CEBPZ (CCAAT/enhancer binding protein (C/EBP), zeta) | protein interactions | 10153 | 39 | 10 | 16036 | 2270 |
PES1,DDX56,UBE3A,SIRT7,LAMTOR3,VAPB,RNF2,HMOX2,NOLC1,PUM3 |
| 4.114e-02 | -3.19 | TUBB1 (tubulin, beta 1 class VI) | protein interactions | 81027 | 39 | 10 | 16036 | 2270 |
SNW1,CUL4A,COPS5,CUL2,SSBP1,COPS6,FBL,ZMYM2,NOP56,SNCA |
| 4.114e-02 | -3.19 | BUD31 (BUD31 homolog) | protein interactions | 8896 | 39 | 10 | 16036 | 2270 |
SNW1,CTNNBL1,UTP14A,TRA2A,ZC3H18,ZNF326,RELB,BMI1,SON,PRPF19 |
| 4.114e-02 | -3.19 | DNAJB6 (DnaJ (Hsp40) homolog, subfamily B, member 6) | protein interactions | 10049 | 39 | 10 | 16036 | 2270 |
MYC,CUL2,HSPB8,ALKBH1,FKBP5,SIRT2,C12orf45,HSPA1A,BAG1,UBC |
| 4.114e-02 | -3.19 | KHDRBS3 (KH domain containing, RNA binding, signal transduction associated 3) | protein interactions | 10656 | 39 | 10 | 16036 | 2270 |
PTBP2,SYNCRIP,HNRNPR,PRPF31,KHDRBS1,ATXN2,SGSM2,FUS,BMI1,PSMF1 |
| 4.114e-02 | -3.19 | KRT6A (keratin 6A, type II) | protein interactions | 3853 | 39 | 10 | 16036 | 2270 |
SHC1,CCDC53,TFIP11,COPS5,CUL2,CCDC85B,EMC8,DSP,KDM1A,RPS6KB2 |
| 4.114e-02 | -3.19 | MLF1 (myeloid leukemia factor 1) | protein interactions | 4291 | 39 | 10 | 16036 | 2270 |
BRCA2,DNAJB6,HERC1,COPS3,HAUS6,RIPK1,ATG2B,CRYBG3,AKAP11,PRKACB |
| 4.114e-02 | -3.19 | JUND (jun D proto-oncogene) | protein interactions | 3727 | 39 | 10 | 16036 | 2270 |
SMAD3,PPARG,COPS5,ACTR3,SLC25A12,BRCA1,FOSL2,MEN1,TPM1,DDIT3 |
| 4.117e-02 | -3.19 | SIRT1 (sirtuin 1) | protein interactions | 23411 | 209 | 39 | 16036 | 2270 |
SART1,NCOR2,MCM10,FOXO1,SMAD7,NAT10,CSNK2A1,SIRT2,ZNF346,FOXO3,HIST2H2AB,SKI,SNW1,RAP1A,ZNHIT6,ZEB1,CDK6,KAT8,BRD4,APEX1,HSPA5,TPM4,SETD7,DOT1L,TAF2,VDR,IRS1,DYNC1H1,POP1,KPNA3,GTF2A1,CHD3,ARNTL,ATG7,NCOR1,MAPT,RBP1,STK4,MEF2C |
| 4.120e-02 | -3.19 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | 117 | 22 | 17758 | 2279 |
LAMA4,SEPHS2,EFNB2,HMGA2,ADAM19,PHLDB2,EVL,UTP14A,PSPC1,PDK4,ENAH,SLC6A8,PPID,VCAN,SLC38A2,H2AFX,SLC16A1,DPEP1,NRP1,ERRFI1,SYNPO,TOP1 |
| 4.120e-02 | -3.19 | PRKACA (protein kinase, cAMP-dependent, catalytic, alpha) | protein interactions | 5566 | 240 | 44 | 16036 | 2270 |
BRAF,PDE4B,PDE3A,CAD,RAP1A,ANXA7,SYN2,PHKA1,CACNB2,VAPB,TRMT10A,ETV1,AKAP11,PRKACB,HMGCR,PPP1R9B,SIK3,CAMKK2,AKAP8L,USP49,RAP1B,GMFB,PTPN12,RYR2,POU2F1,HDAC8,RSBN1,VIM,CAV1,MEF2D,SNAP25,AKAP13,KCNH2,PDE3B,DSP,SH3GL1,ARPC3,DYRK1B,DNAJA3,USP20,TBXA2R,NOLC1,PRKAR2A,MAPT |
| 4.124e-02 | -3.19 | - | gene3d domains | 3.40.20.10 | 24 | 7 | 9988 | 1398 |
SVIL,SEC24A,DBN1,COTL1,SEC24D,SEC24C,GMFB |
| 4.138e-02 | -3.18 | KRT78 (keratin 78, type II) | protein interactions | 196374 | 10 | 4 | 16036 | 2270 |
SIRT2,UCHL5,COPS5,CUL2 |
| 4.138e-02 | -3.18 | ADPRHL2 (ADP-ribosylhydrolase like 2) | protein interactions | 54936 | 10 | 4 | 16036 | 2270 |
NCBP2,IMPDH2,ERC1,FRA10AC1 |
| 4.138e-02 | -3.18 | HSP82 (Hsp90 family chaperone HSP82) | protein interactions | 855836 | 10 | 4 | 16036 | 2270 |
CSNK2A1,CDK4,UBC,CDC37 |
| 4.138e-02 | -3.18 | GLI2 (GLI family zinc finger 2) | protein interactions | 2736 | 10 | 4 | 16036 | 2270 |
ZIC2,SUFU,SPOP,SKI |
| 4.138e-02 | -3.18 | Anapc13 (anaphase promoting complex subunit 13) | protein interactions | 69010 | 10 | 4 | 16036 | 2270 |
ANAPC1,CDC16,ANAPC13,ANAPC4 |
| 4.138e-02 | -3.18 | CALR3 (calreticulin 3) | protein interactions | 125972 | 10 | 4 | 16036 | 2270 |
TMEM132A,SRRM2,UBR5,FAT1 |
| 4.138e-02 | -3.18 | BMP2K (BMP2 inducible kinase) | protein interactions | 55589 | 10 | 4 | 16036 | 2270 |
ABL1,FN1,KDM5B,TERF2 |
| 4.138e-02 | -3.18 | TP53I3 (tumor protein p53 inducible protein 3) | protein interactions | 9540 | 10 | 4 | 16036 | 2270 |
HMBS,TP53BP1,UBR1,H2AFX |
| 4.138e-02 | -3.18 | PPIP5K1 (diphosphoinositol pentakisphosphate kinase 1) | protein interactions | 9677 | 10 | 4 | 16036 | 2270 |
MIF4GD,CYLD,VAC14,WBSCR22 |
| 4.138e-02 | -3.18 | CLUAP1 (clusterin associated protein 1) | protein interactions | 23059 | 10 | 4 | 16036 | 2270 |
SHMT2,CRACR2A,IFT57,CLU |
| 4.138e-02 | -3.18 | PDCD2 (programmed cell death 2) | protein interactions | 5134 | 10 | 4 | 16036 | 2270 |
FKBP5,NCOR1,NFKBIB,USP49 |
| 4.138e-02 | -3.18 | Nup107 (nucleoporin 107) | protein interactions | 103468 | 10 | 4 | 16036 | 2270 |
NUP43,NUP160,NUP133,SEH1L |
| 4.138e-02 | -3.18 | LSM11 (LSM11, U7 small nuclear RNA associated) | protein interactions | 134353 | 10 | 4 | 16036 | 2270 |
PRMT5,LSM10,CLNS1A,TOP3A |
| 4.138e-02 | -3.18 | MYF5 (myogenic factor 5) | protein interactions | 4617 | 10 | 4 | 16036 | 2270 |
ID2,CSNK2A1,ID1,TCF3 |
| 4.138e-02 | -3.18 | RAB40A (RAB40A, member RAS oncogene family) | protein interactions | 142684 | 10 | 4 | 16036 | 2270 |
FAM192A,COPS6,ARIH2,LYRM7 |
| 4.138e-02 | -3.18 | BCS1L (BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone) | protein interactions | 617 | 10 | 4 | 16036 | 2270 |
FUS,DDX24,RBFOX2,MRPL10 |
| 4.138e-02 | -3.18 | PAXBP1 (PAX3 and PAX7 binding protein 1) | protein interactions | 94104 | 10 | 4 | 16036 | 2270 |
BMI1,TFIP11,RSRC1,TERF2 |
| 4.138e-02 | -3.18 | PTPRM (protein tyrosine phosphatase, receptor type, M) | protein interactions | 5797 | 10 | 4 | 16036 | 2270 |
PTPRM,PTPRA,PPFIBP1,PTPRK |
| 4.138e-02 | -3.18 | DLX5 (distal-less homeobox 5) | protein interactions | 1749 | 10 | 4 | 16036 | 2270 |
MSX2,MSX1,DLX2,SPEN |
| 4.138e-02 | -3.18 | TNNT2 (troponin T type 2 (cardiac)) | protein interactions | 7139 | 10 | 4 | 16036 | 2270 |
TNNC1,TPM1,PRKCA,KDM1A |
| 4.138e-02 | -3.18 | Bmi1 (Bmi1 polycomb ring finger oncogene) | protein interactions | 12151 | 10 | 4 | 16036 | 2270 |
PHC2,SCMH1,RNF2,RING1 |
| 4.139e-02 | -3.18 | RNA polymerase II transcription factor binding | molecular function | GO:0001085 | 102 | 20 | 16491 | 2164 |
ATF4,BHLHE40,NOP58,MAD2L2,KDM1A,TCF7L2,SPOP,MKX,SMAD3,RBBP8,GATA6,TP53BP1,HIPK2,ZNHIT6,SPEN,KLF4,TBX3,NCOR1,RBPJ,FBL |
| 4.140e-02 | -3.18 | FA58C_3 | prosite domains | PS50022 | 21 | 6 | 11866 | 1504 |
NRP1,CNTNAP3,CNTNAP3B,MFGE8,DCBLD2,DDR2 |
| 4.142e-02 | -3.18 | CTCCAAG,MIR-432 | MSigDB lists | CTCCAAG,MIR-432 | 79 | 16 | 17758 | 2279 |
DCTN3,HMGA2,PDE4A,FN1,LUZP1,HOMER2,FAM126B,ARL5B,TOX4,KIAA0355,ALKBH8,FNTB,ABCC3,KDM5C,POLE3,PDLIM5 |
| 4.156e-02 | -3.18 | skin-extremity-malignant_melanoma | COSMIC cancer mutations | skin-extremity-malignant_melanoma | 1967 | 277 | 17775 | 2278 |
GGT1,CDCP1,DPH1,TNFRSF21,HLTF,SYNJ1,UBR5,PABPC4,AMBRA1,GIPR,EXOC1,PDZD2,RABGAP1L,ZNF148,HRG,SLC38A6,NRAS,OSBP2,NR6A1,C11orf80,DENND4A,AHNAK,TRRAP,CCNT1,LRRC40,VPS13D,GREB1L,ZNF598,ZNF532,NMD3,PTPN14,HERC2,EP400,CLDN15,DROSHA,CELSR1,ANKRD17,KCNJ14,SLC1A1,ABCA7,TECTA,SH2B3,RBM20,DHX37,SCAF1,CACNB2,VWDE,PIGG,GTF3C3,NOC3L,MAP3K12,PPA1,SAMD3,GATAD2B,COL17A1,STAG1,RREB1,MYO10,PRDM16,ARID5B,RYR2,PTPN12,SNAP25,ARID1A,PLCB1,CPT1A,ANGPTL4,SLC26A11,ATP9B,DYNC1H1,ZNF425,EPRS,LRP1B,ZZEF1,MED15,PURB,TRPM2,TRERF1,SPATA2L,RIBC2,HFM1,VTI1A,MAB21L3,PTPRG,TRIM66,PDE3A,RING1,CHD7,NUBPL,ESAM,ZBED2,ABCA12,ZKSCAN1,KMT2A,LYST,ZCCHC14,MPP6,GARS,KMT2D,RFC3,SFXN4,EIF3J,WDPCP,SLCO6A1,KIAA1586,PNN,POLG2,DSP,TAF2,PES1,KDM4B,ZNF236,POLR3E,CBWD1,KLHDC4,LAMA5,CEP170,CATSPERG,NCOR2,NOSTRIN,SSH2,BRAF,C10orf2,WDR37,BHLHE40,POM121,NEDD4,NEBL,TAF3,RDX,NAV3,MBTPS2,TMC7,FAM98A,TSHZ1,CLYBL,KCNMA1,PACS1,R3HDM2,KLF6,YIF1A,ETFDH,SRCAP,TOE1,BAZ2B,IREB2,HELZ,ATM,MYOM2,APAF1,SORCS2,BRWD3,ANAPC4,ZNF76,CUL7,TRPM6,RNF43,BCOR,STK33,TTI1,SNAPC4,GIT2,ANAPC1,ARHGAP18,MYH3,HKR1,ANKRD11,GPATCH1,POLR3B,ETV1,ZNF3,FMNL3,TXLNG,KATNAL1,ANK2,KMT2C,TMEM132B,TP53BP1,AHNAK2,CSMD3,SGSM2,NOMO3,FAN1,MAPK8IP3,MED13L,SMG7,PCSK7,QSER1,ARID1B,ZNF358,SIPA1L3,ATXN2,SEMA3D,HSD17B14,CAMKK2,TSTA3,ZBED4,OBSCN,WWC1,PRDM1,SYT1,PGD,BICD1,KIAA0754,DNAH17,CASS4,ZFP90,GGT7,N4BP2L2,SART1,UPK3B,PSTPIP2,MYO7A,DENND3,PLXNB1,ZNF608,UBR1,NVL,ARMC5,SNTG2,MYH15,HIBCH,RNF2,AKNAD1,IPO11,CTC1,SEC24A,NARS2,PHLDB2,PRAME,FAM172A,SFSWAP,THSD4,METTL15,POU2F1,NUP214,ARMC4,RANBP2,KPNA3,SRFBP1,FKBP5,HEATR1,SMG1,PARD3,MAP3K13,RFX1,CLSTN2,IGF2BP2,FAM49A,POGZ,PTPN2,SACS,FBXO31,MICAL3,ARNTL2,ADAMTSL3,FGF2,LRRIQ1,KDM5A,DHX34,TOP3A,TEX14,PEAR1,MARS,PDE2A,EIF5B,NAALADL2,PIK3CB,ARMC3,ZNF221,CENPP,MKX,CDH24,SRBD1,VPS37B,TBX3,XPO6 |
| 4.158e-02 | -3.18 | Ovarian Infertility Genes | WikiPathways | WP34 | 32 | 8 | 4455 | 564 |
SMAD3,VDR,EGR1,CDK4,ATM,NCOR1,MLH1,NRIP1 |
| 4.161e-02 | -3.18 | SH3KBP1 (SH3-domain kinase binding protein 1) | protein interactions | 30011 | 203 | 38 | 16036 | 2270 |
SEC24D,KHDRBS1,CSNK1A1,SYNJ1,BIRC2,POM121,PABPC4,NEDD4,ABL1,ASAP1,MCM5,ATXN2,MYC,PPFIBP1,SEC24C,SYNJ2,SERPINH1,MET,SRRM2,PABPC1,DDN,DDX28,PHLDB2,ARHGAP17,CLYBL,PTK2,IMPDH2,ERC1,UBC,SH3GL1,RPA1,CDC16,TTC38,VPS37B,TNFRSF1A,SYNPO,ARHGAP27,ANAPC4 |
| 4.164e-02 | -3.18 | KH_dom_type_1 | interpro domains | IPR004088 | 43 | 10 | 18293 | 2341 |
EXOSC2,ASCC1,NOVA2,ANKRD17,KHDRBS1,MEX3A,IGF2BP2,MEX3B,IGF2BP1,IGF2BP3 |
| 4.171e-02 | -3.18 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN | 183 | 32 | 17758 | 2279 |
CARS,FBXO45,ZNF706,MIF4GD,FAM208B,CUL4A,TUBE1,RCAN1,PHGDH,NUP160,SCAF8,DDIT4,TERF2IP,ANXA7,COPS4,POLR1E,NAA35,IPO11,PCCA,MTHFD1L,PPIP5K2,ZNF251,TCF7L2,KIF16B,PAF1,ASCC3,RARS,TASP1,BAZ2B,LUC7L3,CUL2,METTL2B |
| 4.171e-02 | -3.18 | GSE2706_UNSTIM_VS_8H_LPS_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_DC_UP | 183 | 32 | 17758 | 2279 |
KCTD7,MCM6,STX8,AARS2,PLA2G12A,ACOT11,VCL,LRP3,MAML3,MSI2,FADS1,KIAA1143,DDX41,SFXN4,NFIA,IMPDH2,CASC1,LYRM7,STOML2,RPA1,YIF1A,ITPRIPL1,ELP2,HSPBAP1,MKL2,TMEM117,PTPN4,DNAJC12,DTD1,TPM1,ZNF589,ECHDC1 |
| 4.171e-02 | -3.18 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 183 | 32 | 17758 | 2279 |
TCF12,COMMD10,AK2,CCDC53,NDUFB5,JMJD6,MLH1,CD226,GFM2,DDIT4,TBC1D22A,SHMT2,CPSF3,VCL,MPST,HN1,MCEE,POU2F1,IMPDH2,GALK2,CLNS1A,HPRT1,SRBD1,MPV17,DTD1,TMEM101,APAF1,BRCC3,IFITM2,COPS6,TATDN1,TXN2 |
| 4.175e-02 | -3.18 | symbiosis, encompassing mutualism through parasitism | biological process | GO:0044403 | 737 | 112 | 16441 | 2138 |
USP7,CHMP2A,THOC5,CUL7,RAB11FIP4,CUL4A,UBN1,MFGE8,RPS29,SMARCA4,NUP43,AP1B1,NUP160,GBF1,HSPA1A,SMARCB1,VPS18,RPS16,SHC1,NUP133,PPID,AP1M1,RAN,HCFC2,SEH1L,CARM1,RBCK1,BRD4,KRT7,RNMT,RAB7A,NFIA,TCEB3,VIM,CAV1,NUP214,UBR4,CXADR,CDHR3,TAF9B,DDX3X,TAF2,SMAD3,RANBP2,SUPT4H1,KPNA3,CCNT1,HIPK2,ITGA2,ATG7,TNFRSF1A,H2AFX,DPP4,SCARB1,COPS6,XRCC4,AP2S1,CHMP4C,EFNB2,HMGA2,TAF1,SUPT6H,ANKRD17,VTA1,NFX1,ATF7IP,GAS6,TRIM22,PSMF1,POM121,NEDD4,ELL,SNW1,UBE3A,TAF3,BANF1,GTF2H1,VAPB,LRSAM1,CAV2,TOP1,GTF2H3,VPS37A,POLA1,EIF4A2,LIG4,PSMA1,PACS1,NELFA,SUPT5H,VAC14,UBC,ISG15,POLR2A,HSPA1B,SRCAP,BICD1,KPNA1,SYNCRIP,GTF2A1,RPL28,CDK9,SPEN,VPS37B,SET,CUL2,TAF4,FDPS,RRAGA,NCBP2,TAF12,SLC52A2 |
| 4.175e-02 | -3.18 | interspecies interaction between organisms | biological process | GO:0044419 | 737 | 112 | 16441 | 2138 |
USP7,CHMP2A,THOC5,CUL7,RAB11FIP4,CUL4A,UBN1,MFGE8,RPS29,SMARCA4,NUP43,AP1B1,NUP160,GBF1,HSPA1A,SMARCB1,VPS18,RPS16,SHC1,NUP133,PPID,AP1M1,RAN,HCFC2,SEH1L,CARM1,RBCK1,BRD4,KRT7,RNMT,RAB7A,NFIA,TCEB3,VIM,CAV1,NUP214,UBR4,CXADR,CDHR3,TAF9B,DDX3X,TAF2,SMAD3,RANBP2,SUPT4H1,KPNA3,CCNT1,HIPK2,ITGA2,ATG7,TNFRSF1A,H2AFX,DPP4,SCARB1,COPS6,XRCC4,AP2S1,CHMP4C,EFNB2,HMGA2,TAF1,SUPT6H,ANKRD17,VTA1,NFX1,ATF7IP,GAS6,TRIM22,PSMF1,POM121,NEDD4,ELL,SNW1,UBE3A,TAF3,BANF1,GTF2H1,VAPB,LRSAM1,CAV2,TOP1,GTF2H3,VPS37A,POLA1,EIF4A2,LIG4,PSMA1,PACS1,NELFA,SUPT5H,VAC14,UBC,ISG15,POLR2A,HSPA1B,SRCAP,BICD1,KPNA1,SYNCRIP,GTF2A1,RPL28,CDK9,SPEN,VPS37B,SET,CUL2,TAF4,FDPS,RRAGA,NCBP2,TAF12,SLC52A2 |
| 4.181e-02 | -3.17 | YCATTAA_UNKNOWN | MSigDB lists | YCATTAA_UNKNOWN | 531 | 82 | 17758 | 2279 |
TRERF1,NF1,PRKCSH,MFGE8,C1QTNF7,TUBE1,NECAP1,BCOR,GBF1,UBR5,PCDH7,RTN1,ZNF827,PRKD3,SRSF2,ARHGAP18,ABCA12,ZFHX3,JAZF1,CYB5D1,C15orf40,PAK1IP1,ZEB1,ETF1,ZBTB17,SOBP,MPP6,NRAS,SFSWAP,NPM3,SATB2,MARCH6,SOX4,KCNH2,HSD3B7,PLIN2,TAF2,BAZ1A,MSRA,TCF7L1,RBBP8,AHNAK,HOXA3,HSPB8,LARGE,CSMD3,C3orf35,RUNX1,NRP1,ZNF532,RAB30,LRCH1,RHOBTB1,DPF2,IP6K2,ENOX1,CHD5,ATXN7L1,MCAM,NEBL,TIMELESS,NLGN3,C15orf41,RPS6KB2,TSHZ1,MSI2,IL11RA,AP4S1,FOXN3,POLA1,KCNMA1,PRDM1,PTK2,KLF6,MBNL2,DDX49,NR2F1,NSD1,POLE2,PMEPA1,VPS37B,NR2F2 |
| 4.183e-02 | -3.17 | cardiac muscle tissue morphogenesis | biological process | GO:0055008 | 54 | 12 | 16441 | 2138 |
FKBP1A,TNNC1,PTCD2,TTN,DLL4,SIRT6,SMAD7,RYR2,RBPJ,TPM1,DSP,FOXC1 |
| 4.183e-02 | -3.17 | endocrine pancreas development | biological process | GO:0031018 | 54 | 12 | 16441 | 2138 |
GATA6,FOXO1,BMP4,IL6R,MEN1,SOX4,ONECUT2,PDE3B,CDK6,BMP6,ANXA1,GIPR |
| 4.188e-02 | -3.17 | RPS2 (ribosomal protein S2) | protein interactions | 6187 | 259 | 47 | 16036 | 2270 |
NIFK,CUL7,CUL4A,FN1,DDX18,SIRT7,RPS29,NAT10,TIMM10,PELP1,NOP56,MRPS11,KRI1,MPHOSPH10,RPS16,ANXA7,RNF2,FBL,SRRM2,PRMT3,ATP6V0D1,HNRNPM,NOM1,RPS6KB2,SNU13,MRPS10,RHOT2,CLNS1A,DHX57,NAP1L5,DDX3X,TOE1,ASCC3,TSR1,NOL10,MYBBP1A,GADD45A,RAD18,RPL28,HNRNPR,COPS5,CUL2,H2AFX,PURB,PTRH2,RIOK1,COPS6 |
| 4.188e-02 | -3.17 | dicarboxylic acid transport | biological process | GO:0006835 | 72 | 15 | 16441 | 2138 |
GLS,BDNF,SLC7A11,STX1A,NF1,ARL6IP5,NTSR1,SLC38A2,PRAF2,SLC25A12,SLC25A11,SNAP25,SYT1,SLC26A11,SLC1A1 |
| 4.188e-02 | -3.17 | somatic stem cell population maintenance | biological process | GO:0035019 | 72 | 15 | 16441 | 2138 |
TCF7L1,BRAF,CUL4A,FGF2,PRDM16,KLF4,VPS72,LIG4,PBX1,RBPJ,SOX4,POLR2A,TCF7L2,KAT6A,SKI |
| 4.192e-02 | -3.17 | costamere | cellular component | GO:0043034 | 21 | 6 | 17570 | 2233 |
FLNC,SVIL,AHNAK,VCL,ANK2,AHNAK2 |
| 4.192e-02 | -3.17 | centriolar satellite | cellular component | GO:0034451 | 21 | 6 | 17570 | 2233 |
CCDC113,PCNT,PIBF1,CEP290,SDCCAG8,PAX2 |
| 4.193e-02 | -3.17 | POP4 (POP4 homolog, ribonuclease P/MRP subunit) | protein interactions | 10775 | 19 | 6 | 16036 | 2270 |
C18orf21,RPP30,POP1,CBWD1,POP5,PRKCSH |
| 4.193e-02 | -3.17 | NPHP1 (nephronophthisis 1 (juvenile)) | protein interactions | 4867 | 19 | 6 | 16036 | 2270 |
CEP164,FLNC,TNK2,ARHGAP32,KHDRBS1,FLNB |
| 4.193e-02 | -3.17 | NUBP1 (nucleotide binding protein 1) | protein interactions | 4682 | 19 | 6 | 16036 | 2270 |
DCTPP1,XPNPEP1,PDLIM1,NOL3,ARIH2,HK2 |
| 4.193e-02 | -3.17 | PRRC2B (proline-rich coiled-coil 2B) | protein interactions | 84726 | 19 | 6 | 16036 | 2270 |
ATXN1,USP11,EHMT2,SIRT7,EIF3H,RERE |
| 4.193e-02 | -3.17 | ISY1-RAB43 (ISY1-RAB43 readthrough) | protein interactions | 100534599 | 19 | 6 | 16036 | 2270 |
SF3A3,CPSF3,PLRG1,BUD31,SF3A1,PRPF19 |
| 4.193e-02 | -3.17 | ZC3H14 (zinc finger CCCH-type containing 14) | protein interactions | 79882 | 19 | 6 | 16036 | 2270 |
KRT20,RNF2,CUL7,UBAP2,SIRT7,DDIT3 |
| 4.193e-02 | -3.17 | SPTBN2 (spectrin, beta, non-erythrocytic 2) | protein interactions | 6712 | 19 | 6 | 16036 | 2270 |
KDM5C,MLH1,MINK1,CELSR3,SIRT7,SPTAN1 |
| 4.193e-02 | -3.17 | HSPB8 (heat shock 22kDa protein 8) | protein interactions | 26353 | 19 | 6 | 16036 | 2270 |
CSNK2A1,PRKCA,DNAJB6,CIAPIN1,SNCA,HSPB8 |
| 4.193e-02 | -3.17 | ALAD (aminolevulinate dehydratase) | protein interactions | 210 | 19 | 6 | 16036 | 2270 |
GPN1,P3H1,SURF2,ALAD,LPP,TOM1L1 |
| 4.193e-02 | -3.17 | TAF1C (TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa) | protein interactions | 9013 | 19 | 6 | 16036 | 2270 |
UBTF,RRN3,TAF12,POLR1E,MYC,H2AFX |
| 4.193e-02 | -3.17 | TMEFF1 (transmembrane protein with EGF-like and two follistatin-like domains 1) | protein interactions | 8577 | 19 | 6 | 16036 | 2270 |
EXOC1,CLDND1,INTS7,FGF2,BCS1L,SLC39A11 |
| 4.193e-02 | -3.17 | LYPLA1 (lysophospholipase I) | protein interactions | 10434 | 19 | 6 | 16036 | 2270 |
APRT,ANXA2,ASNS,FN1,PRDX6,TTC38 |
| 4.193e-02 | -3.17 | KCTD10 (potassium channel tetramerization domain containing 10) | protein interactions | 83892 | 19 | 6 | 16036 | 2270 |
RNF2,COPS6,FMNL1,COPS5,UBXN1,UBC |
| 4.193e-02 | -3.17 | IWS1 (IWS1 homolog (S. cerevisiae)) | protein interactions | 55677 | 19 | 6 | 16036 | 2270 |
CTR9,CSNK2A1,SHMT2,SUPT6H,SETD2,POLR2A |
| 4.193e-02 | -3.17 | Cdc20 (cell division cycle 20) | protein interactions | 107995 | 19 | 6 | 16036 | 2270 |
ANAPC1,CDC16,ANAPC13,ANAPC4,ANAPC10,NUDC |
| 4.194e-02 | -3.17 | BAG1 (BCL2-associated athanogene) | protein interactions | 573 | 72 | 16 | 16036 | 2270 |
XPO5,RANGAP1,HSPA1A,HSPA1B,SH3GL1,TOM1L1,ABL1,VDR,DNAJB6,LTN1,ANP32B,CD44,MET,PEG10,PPIL3,MAPT |
| 4.194e-02 | -3.17 | SNX2 (sorting nexin 2) | protein interactions | 6643 | 72 | 16 | 16036 | 2270 |
DNM3,LAMC1,PPAT,ASUN,TSN,RTN4,IMPDH2,ERC1,USP46,C1orf122,RNF40,ATG7,VAPB,HIRIP3,RDX,MET |
| 4.195e-02 | -3.17 | small_intestine | COSMIC cancer mutations | small_intestine | 258 | 43 | 17775 | 2278 |
DMXL2,TNIK,BRAF,PHF3,BIRC6,KIAA0232,NHS,TRPM6,MLH1,PLXNB1,PCDH7,SMARCB1,ABL1,NDUFV1,NUP133,NVL,MARVELD2,PDS5B,MAD1L1,VPS52,MET,MICAL3,TRAPPC9,NRAS,COL5A2,SYNGAP1,SETD2,PREX1,ADAM32,MEGF11,MEN1,CORIN,DDX60,C1orf174,FGFR1,OSBPL1A,SRCAP,ASCC3,SERINC1,DNAH17,ATM,SVIL,MAP2K4 |
| 4.196e-02 | -3.17 | MODULE_207 | MSigDB lists | MODULE_207 | 210 | 36 | 17758 | 2279 |
PPDPF,IFT57,MAP3K13,ARID2,RBFOX2,CD99L2,LYRM2,MGA,TOX4,ANKRD13A,PDZD2,DUS4L,ABCA5,SNTG2,VAPB,RAN,FMNL2,ACTR3B,CSGALNACT2,DDHD1,SIK3,RBCK1,SMARCAD1,TYW1,NLN,MRRF,MTHFD1L,ZNF655,MRPL36,PDE8B,NSD1,INSIG1,POLE2,SVIL,SPOCK3,DDIT3 |
| 4.196e-02 | -3.17 | VANOEVELEN_MYOGENESIS_SIN3A_TARGETS | MSigDB lists | VANOEVELEN_MYOGENESIS_SIN3A_TARGETS | 210 | 36 | 17758 | 2279 |
CTU2,MINK1,C17orf80,ATP6V1A,SUPT6H,URB2,ST6GAL1,OLA1,PPP2R2A,LPCAT3,PIBF1,ABHD6,ETFB,TERF2IP,PHF5A,SURF2,NOP16,VPS52,ANXA5,SUCLG2,FHIT,TOMM34,GNG5,MINA,NLN,TMEM206,SH3GL1,GEMIN5,BAZ1A,FAM114A2,HIPK2,MBTD1,SORCS2,NMD3,HS2ST1,RNF114 |
| 4.197e-02 | -3.17 | signal transduction by p53 class mediator | biological process | GO:0072331 | 135 | 25 | 16441 | 2138 |
CRADD,ATRX,TMEM109,CDIP1,USP10,PSMA1,SHISA5,BRCA1,ZNF346,SOX4,FOXO3,PSMF1,UBC,DDIT4,SNW1,BRCA2,MYBBP1A,PMAIP1,HIPK2,TRIAP1,ATM,AEN,FHIT,ZMAT3,PERP |
| 4.197e-02 | -3.17 | STEIN_ESRRA_TARGETS_DN | MSigDB lists | STEIN_ESRRA_TARGETS_DN | 98 | 19 | 17758 | 2279 |
PEA15,EXOSC2,SIGMAR1,ZHX3,RBFOX2,TRIO,NOL6,ATG2B,TUBB6,TGFBR2,VDR,KIDINS220,SMARCC1,INTS12,NR2F2,CAV2,MID1,LRRC41,MORC2 |
| 4.199e-02 | -3.17 | central nervous system development | biological process | GO:0007417 | 859 | 129 | 16441 | 2138 |
IMMP2L,MYCBP2,NF1,ATRX,SIRT2,SEC16A,AARS,RAC3,WNT2B,SKI,ABL2,ZFHX3,ZEB1,ZNF148,RAN,CDK6,MPST,HSPA5,PSMG1,C5AR1,SEMA3F,EFHC1,SOX4,TCTN1,SH3GL1,HPRT1,TCF7L1,BRCA2,DLX2,CLU,RUNX1,NRP1,FBXO45,CELSR1,EGR1,PAX2,MAPK8IP3,ZIC2,PHGDH,TGFBR2,CHD5,PITPNM1,DDIT4,UBE3A,SLC7A11,TSPAN2,CEP290,ATIC,ATXN2,NDRG4,ANP32B,IGF2BP1,ATP6V0D1,NT5E,KCNQ3,SETD2,ELP3,LIG4,ATAT1,ARID1A,PLCB1,TCF7L2,NR2F1,NME7,HIF1A,VCAN,ZNF430,PEX13,HMBS,NCOR1,NAPA,ID1,DLL4,PCNT,PAFAH1B1,NPAS2,RBFOX2,C16orf45,RPGRIP1L,KDM1A,CHD7,UCHL5,SNTG2,HTRA2,GRHL3,VIM,SATB2,FGFR1,ARMC4,G6PD,ARL13B,H2AFX,ATG7,SLC4A7,EIF2B3,MAPT,ID2,MAP1S,RCAN1,RTN4,GDPD5,GIGYF2,GART,SCN1B,DYNC2H1,NLGN3,SOX6,KDM6B,FGF9,MSX1,TRNP1,ZC4H2,FZD3,LDHA,PTK2,MEN1,FOXC1,DKK1,RERE,AGTPBP1,HERC1,TBX3,ATM,BMP4,APAF1,RBPJ,MYRF,NR2F2,STK4 |
| 4.200e-02 | -3.17 | central_nervous_system-brain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_I | 43 | 10 | 17775 | 2278 |
BRAF,NRAS,NF1,ATRX,KLF4,ATM,BCOR,MET,KIAA1549,FGFR1 |
| 4.200e-02 | -3.17 | R3H_dom | interpro domains | IPR001374 | 11 | 4 | 18293 | 2341 |
R3HDM1,NFX1,R3HDM2,PARN |
| 4.200e-02 | -3.17 | WH1/EVH1_dom | interpro domains | IPR000697 | 11 | 4 | 18293 | 2341 |
ENAH,SPRED2,EVL,HOMER2 |
| 4.200e-02 | -3.17 | Single_hybrid_motif | interpro domains | IPR011053 | 11 | 4 | 18293 | 2341 |
DLST,PCCA,FAM206A,GCSH |
| 4.200e-02 | -3.17 | Methyl_CpG_DNA-bd | interpro domains | IPR001739 | 11 | 4 | 18293 | 2341 |
MBD6,BAZ2B,BAZ2A,MBD2 |
| 4.200e-02 | -3.17 | Filamin/ABP280_repeat-like | interpro domains | IPR017868 | 11 | 4 | 18293 | 2341 |
FLNC,MYCBP2,FLNB,KDELC1 |
| 4.200e-02 | -3.17 | DNA-bd_dom | interpro domains | IPR016177 | 11 | 4 | 18293 | 2341 |
MBD6,BAZ2B,BAZ2A,MBD2 |
| 4.200e-02 | -3.17 | GBD/FH3_dom | interpro domains | IPR014768 | 11 | 4 | 18293 | 2341 |
INF2,FMNL3,FMNL1,FMNL2 |
| 4.205e-02 | -3.17 | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | 299 | 49 | 17758 | 2279 |
BTBD2,CLK1,UROD,TMEM109,RSL1D1,GRINA,SLC6A8,PHLDA2,FAM8A1,NDUFS7,FKBP1A,RNF40,NPRL2,NDUFV1,ZKSCAN1,PMAIP1,MCM5,TRIAP1,SHMT2,SERPINH1,OGG1,TERF2,RPS6KB2,FADS1,TRIM13,IL11RA,SIGMAR1,PSMC3IP,WBSCR22,SMARCD3,GNL1,RABAC1,CYB5B,ISG15,POLR2A,MAT2A,NCDN,NEU1,GLS,SLC30A3,ZNF330,PQBP1,CCDC85B,NCBP2,PRPF4,IFITM2,TNFRSF10D,AP2S1,BAG1 |
| 4.206e-02 | -3.17 | regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001242 | 148 | 27 | 16441 | 2138 |
MSX1,CYLD,MCL1,GRINA,CAV1,NOL3,OPA1,HSPA1A,HERPUD1,KDM1A,SPOP,TAF9B,PTPN2,DDX3X,SKIL,RRN3,PMAIP1,TMEM161A,HIF1A,TRAP1,TRIAP1,FIS1,CLU,YBX3,CD44,HTRA2,DDIT3 |
| 4.206e-02 | -3.17 | circadian rhythm | biological process | GO:0007623 | 148 | 27 | 16441 | 2138 |
ARNTL2,ATF4,EGR1,NPAS2,CDK4,KDM5A,KCNMA1,ID2,BTBD9,BHLHE40,CPT1A,UBC,NAMPT,HTR7,MYBBP1A,ZFHX3,PER1,ARNTL,RELB,TIMELESS,NCOR1,PRMT5,NRIP1,NOCT,PRF1,KMT2A,TOP1 |
| 4.225e-02 | -3.16 | TSR1 (TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)) | protein interactions | 55720 | 95 | 20 | 16036 | 2270 |
DDX18,SIRT7,RPS29,LAMTOR3,NAT10,WDR26,TMEM177,RBM19,CYB5B,POLR3A,RPA1,RIOK2,POLR3D,SUB1,RPS16,POLR1B,POLR3B,POLR1C,FTSJ3,SERBP1 |
| 4.225e-02 | -3.16 | HSF1 (heat shock transcription factor 1) | protein interactions | 3297 | 95 | 20 | 16036 | 2270 |
TAF1,ANKMY2,CSNK2A1,SUMO3,SMARCA4,SYMPK,AARS,HSPA1A,SMARCB1,SUB1,UBE3A,KPNA3,SURF2,CHD3,PPID,FKBP5,DTD1,LRSAM1,CDK6,IPO11 |
| 4.225e-02 | -3.16 | human chr7q22.3 | chromosome location | human chr7q22.3 | 14 | 4 | 26250 | 2590 |
ATXN7L1,BCAP29,NAMPT,CDHR3 |
| 4.225e-02 | -3.16 | human chr4q23 | chromosome location | human chr4q23 | 14 | 4 | 26250 | 2590 |
ADH5,TRMT10A,TSPAN5,LAMTOR3 |
| 4.227e-02 | -3.16 | PROTEIN_C_TERMINUS_BINDING | MSigDB lists | PROTEIN_C_TERMINUS_BINDING | 73 | 15 | 17758 | 2279 |
DST,ABL1,USP7,SMARCC1,ATXN2,SDCBP2,HIC2,DLG4,LIG4,ATXN1,EFHC1,MAGI1,XRCC4,PABPC1,PEX1 |
| 4.230e-02 | -3.16 | SRPK1 (SRSF protein kinase 1) | protein interactions | 6732 | 228 | 42 | 16036 | 2270 |
ARHGAP26,SART1,NOL4L,DROSHA,CLK1,SIRT7,NAT10,SF3A3,PPIL1,SPATS2,RSRC1,MRPS11,SRSF2,ECM1,NSRP1,NOP16,IFIT5,HIRIP3,AHCYL1,YBX3,SRRM2,PABPC1,HNRNPM,SRPK2,RPS6KB2,SCAF11,LAMC1,APEX1,PNN,PTK2,SON,FKBP3,VDR,CAMK2D,CACNB1,ALKBH3,COPS5,LUC7L3,ARHGAP12,ZRANB2,FUS,C18orf25 |
| 4.230e-02 | -3.16 | CAGCTG_V$AP4_Q5 | MSigDB lists | CAGCTG_V$AP4_Q5 | 1429 | 205 | 17758 | 2279 |
GNB3,CUL7,DPH1,TMEM109,CACNA1H,CHAC1,UBR5,GABPB2,WNT2B,PHKA1,ANAPC10,MYH3,METTL8,RNF111,SLC35C2,YARS,HCFC2,ETV1,ZMYM2,OGG1,SPAG6,ZNF646,FLNC,BAZ2A,ANK2,EYA3,HSPA5,KSR2,HSH2D,KRTCAP2,KCNH2,SOX4,SGK2,STOML2,YTHDF2,SPOP,UBTF,EPN2,EIF4ENIF1,TP53BP1,DNAJC1,LUC7L3,ARL6IP5,RAD51B,CSMD3,XPNPEP1,GREB1L,FIS1,RUNX1,MAGI1,SPOCK2,DMTF1,SLC25A26,ZMAT3,MEF2C,TNNC1,PIGN,CLDN15,EGR1,STXBP6,PAX2,DPF2,C16orf52,HES6,ZFP36L1,BARX2,PRPF39,TGFBR2,DDIT4,SH2B3,ELL,NAV1,MCAM,SLC7A11,PI4KB,CACNB2,PDE10A,MYC,ATP6V0D1,USP49,PPAT,RDH10,JMJD1C,WDR25,OBSCN,RABAC1,ARID1A,SUPT5H,MBNL2,ONECUT2,NCDN,EXOC6,NAP1L5,APBB3,SERF2,RPL28,HIF1A,CCDC85B,TMEM182,MACROD1,BRSK2,TCF12,DLL4,SYT17,ID1,MAP2K5,TRERF1,MMRN2,ATP6V1A,RBFOX2,MYO7A,CD99L2,TMEM104,TNKS1BP1,PDE3A,DENR,VPS18,SPG21,TMEM184A,JAG1,KDM2A,ARMC5,VGF,NBEA,ETF1,MGLL,PLEKHA4,MOSPD1,HN1,SOBP,BRD4,TUBA1A,KIRREL2,MTIF2,C1QTNF1,WDPCP,LGALS1,GRHL3,MEF2D,HSD3B7,BTBD11,ZBTB25,ZFAND3,SIX5,HOXA3,PAM,TRAF3,RPS6KB1,LAMA5,MID1,RAB30,LRCH1,ATXN7L2,HMGA2,ESCO1,MAP3K13,CA11,VPS45,CLSTN2,ATF7IP,RCAN1,TGFB2,FOXP1,MBNL1,BMP6,RSRC1,GIGYF2,NEDD4,MAN1A1,ABL1,PEX7,FAM50A,SUV39H2,PVRL3,PRICKLE2,NLGN3,LDLRAD3,ZNF710,AMOT,PNMA1,C12orf4,NAV3,SPTAN1,FAM98A,PPP1R9B,IL11RA,ZFYVE1,KCNMA1,PTK2,UBE2K,NAPEPLD,INF2,CACNB1,SET,TBX3,SRD5A3,BCAS3,EIF2S1,SVIL,DOCK6,NUDT22,KIF1B,KDM4C,CORO2B,CTXN1 |
| 4.234e-02 | -3.16 | BCAT_BILD_ET_AL_DN | MSigDB lists | BCAT_BILD_ET_AL_DN | 43 | 10 | 17758 | 2279 |
PRPF38B,LSS,ASH1L,RAP1A,SHC1,CLK1,ZNF236,IRAK2,ATP9B,ZSWIM6 |
| 4.234e-02 | -3.16 | REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | MSigDB lists | REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | 43 | 10 | 17758 | 2279 |
EXOSC2,DCP1B,EIF4A2,CNOT6,EXOSC4,PARN,TNKS1BP1,CNOT4,PABPC1,EDC3 |
| 4.234e-02 | -3.16 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | MSigDB lists | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | 43 | 10 | 17758 | 2279 |
SNW1,NCOR2,HIF1A,TLE3,MYC,HDAC8,TBL1X,NCOR1,RBPJ,MAML3 |
| 4.234e-02 | -3.16 | MODULE_158 | MSigDB lists | MODULE_158 | 43 | 10 | 17758 | 2279 |
RFC4,RFC3,MCM6,BRCA2,POLE2,PRIM2,POLA1,SSBP1,CHAF1A,RPA1 |
| 4.234e-02 | -3.16 | BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP | 43 | 10 | 17758 | 2279 |
RFC4,SHC1,UBAP2L,ENAH,ISG20L2,LARP4B,PEG10,PLCB1,PNMA1,TMPO |
| 4.239e-02 | -3.16 | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | MSigDB lists | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | 11 | 4 | 17758 | 2279 |
ATF4,DDIT3,HSPA5,MBTPS2 |
| 4.239e-02 | -3.16 | ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | ENDOTHELIAL_CELL_MIGRATION | 11 | 4 | 17758 | 2279 |
MYH9,AMOT,NF1,PRSS3 |
| 4.239e-02 | -3.16 | PURINE_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | PURINE_NUCLEOTIDE_METABOLIC_PROCESS | 11 | 4 | 17758 | 2279 |
HPRT1,AMPD3,PPAT,OLA1 |
| 4.239e-02 | -3.16 | PID_INTEGRIN4_PATHWAY | MSigDB lists | PID_INTEGRIN4_PATHWAY | 11 | 4 | 17758 | 2279 |
LAMA2,ITGB4,LAMC1,LAMA5 |
| 4.239e-02 | -3.16 | REACTOME_PYRIMIDINE_CATABOLISM | MSigDB lists | REACTOME_PYRIMIDINE_CATABOLISM | 11 | 4 | 17758 | 2279 |
NT5C,NT5M,UPP1,NT5E |
| 4.239e-02 | -3.16 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | MSigDB lists | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | 11 | 4 | 17758 | 2279 |
SNAP25,STX1A,SYN2,SYT1 |
| 4.239e-02 | -3.16 | MUNSHI_MULTIPLE_MYELOMA_DN | MSigDB lists | MUNSHI_MULTIPLE_MYELOMA_DN | 11 | 4 | 17758 | 2279 |
SKIL,SMARCA4,NPRL2,DKC1 |
| 4.239e-02 | -3.16 | STEGMEIER_PRE-MITOTIC_CELL_CYCLE_REGULATORS | MSigDB lists | STEGMEIER_PRE-MITOTIC_CELL_CYCLE_REGULATORS | 11 | 4 | 17758 | 2279 |
LTN1,CYLD,RAD18,RING1 |
| 4.239e-02 | -3.16 | ENDONUCLEASE_ACTIVITY_GO_0016893 | MSigDB lists | ENDONUCLEASE_ACTIVITY_GO_0016893 | 11 | 4 | 17758 | 2279 |
RPP30,POP1,EXO1,APEX1 |
| 4.239e-02 | -3.16 | FATTY_ACID_BETA_OXIDATION | MSigDB lists | FATTY_ACID_BETA_OXIDATION | 11 | 4 | 17758 | 2279 |
ACADS,CPT1A,ECH1,BDH2 |
| 4.240e-02 | -3.16 | extremity | COSMIC cancer mutations | extremity | 1968 | 277 | 17775 | 2278 |
GGT1,CDCP1,DPH1,TNFRSF21,HLTF,SYNJ1,UBR5,PABPC4,AMBRA1,GIPR,EXOC1,PDZD2,RABGAP1L,ZNF148,HRG,SLC38A6,NRAS,OSBP2,NR6A1,C11orf80,DENND4A,AHNAK,TRRAP,CCNT1,LRRC40,VPS13D,GREB1L,ZNF598,ZNF532,NMD3,PTPN14,HERC2,EP400,CLDN15,DROSHA,CELSR1,ANKRD17,KCNJ14,SLC1A1,ABCA7,TECTA,SH2B3,RBM20,DHX37,SCAF1,CACNB2,VWDE,PIGG,GTF3C3,NOC3L,MAP3K12,PPA1,SAMD3,GATAD2B,COL17A1,STAG1,RREB1,MYO10,PRDM16,ARID5B,RYR2,PTPN12,SNAP25,ARID1A,PLCB1,CPT1A,ANGPTL4,SLC26A11,ATP9B,DYNC1H1,ZNF425,EPRS,LRP1B,ZZEF1,MED15,PURB,TRPM2,TRERF1,SPATA2L,RIBC2,HFM1,VTI1A,MAB21L3,PTPRG,TRIM66,PDE3A,RING1,CHD7,NUBPL,ESAM,ZBED2,ABCA12,ZKSCAN1,KMT2A,LYST,ZCCHC14,MPP6,GARS,KMT2D,RFC3,SFXN4,EIF3J,WDPCP,SLCO6A1,KIAA1586,PNN,POLG2,DSP,TAF2,PES1,KDM4B,ZNF236,POLR3E,CBWD1,KLHDC4,LAMA5,CEP170,CATSPERG,NCOR2,NOSTRIN,SSH2,BRAF,C10orf2,WDR37,BHLHE40,POM121,NEDD4,NEBL,TAF3,RDX,NAV3,MBTPS2,TMC7,FAM98A,TSHZ1,CLYBL,KCNMA1,PACS1,R3HDM2,KLF6,YIF1A,ETFDH,SRCAP,TOE1,BAZ2B,IREB2,HELZ,ATM,MYOM2,APAF1,SORCS2,BRWD3,ANAPC4,ZNF76,CUL7,TRPM6,RNF43,BCOR,STK33,TTI1,SNAPC4,GIT2,ANAPC1,ARHGAP18,MYH3,HKR1,ANKRD11,GPATCH1,POLR3B,ETV1,ZNF3,FMNL3,TXLNG,KATNAL1,ANK2,KMT2C,TMEM132B,TP53BP1,AHNAK2,CSMD3,SGSM2,NOMO3,FAN1,MAPK8IP3,MED13L,SMG7,PCSK7,QSER1,ARID1B,ZNF358,SIPA1L3,ATXN2,SEMA3D,HSD17B14,CAMKK2,TSTA3,ZBED4,OBSCN,WWC1,PRDM1,SYT1,PGD,BICD1,KIAA0754,DNAH17,CASS4,ZFP90,GGT7,N4BP2L2,SART1,UPK3B,PSTPIP2,MYO7A,DENND3,PLXNB1,ZNF608,UBR1,NVL,ARMC5,SNTG2,MYH15,HIBCH,RNF2,AKNAD1,IPO11,CTC1,SEC24A,NARS2,PHLDB2,PRAME,FAM172A,SFSWAP,THSD4,METTL15,POU2F1,NUP214,ARMC4,RANBP2,KPNA3,SRFBP1,FKBP5,HEATR1,SMG1,PARD3,MAP3K13,RFX1,CLSTN2,IGF2BP2,FAM49A,POGZ,PTPN2,SACS,FBXO31,MICAL3,ARNTL2,ADAMTSL3,FGF2,LRRIQ1,KDM5A,DHX34,TOP3A,TEX14,PEAR1,MARS,PDE2A,EIF5B,NAALADL2,PIK3CB,ARMC3,ZNF221,CENPP,MKX,CDH24,SRBD1,VPS37B,TBX3,XPO6 |
| 4.250e-02 | -3.16 | snRNA binding | molecular function | GO:0017069 | 31 | 8 | 16491 | 2164 |
GEMIN5,SNU13,CCNT1,PRPF31,CDK9,PRPF4,NCBP2,TROVE2 |
| 4.252e-02 | -3.16 | central_nervous_system-spinal_cord-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-spinal_cord-glioma-ependymoma | 67 | 14 | 17775 | 2278 |
EXO1,DST,ARNTL2,ANKRD13A,TRIB3,FMNL3,ADAMTSL3,MCM5,CCDC40,PRICKLE2,PLEKHM3,BCOR,C12orf4,CTC1 |
| 4.252e-02 | -3.16 | GSE27786_BCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_DN | 190 | 33 | 17758 | 2279 |
VIPR1,SARS,HM13,LUZP1,CCDC53,SLK,ARL15,NAT10,RNF24,ST3GAL6,MBNL1,FAM8A1,ABCA7,ARHGAP18,SCAF1,IGF2BP1,PABPC1,SLC25A1,TMLHE,HN1,DNMBP,CRIM1,PCCA,MAP7D1,ATP8B2,RETSAT,TASP1,PDLIM1,SRBD1,CHD3,INTS5,PAM,CNDP2 |
| 4.252e-02 | -3.16 | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN | MSigDB lists | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN | 190 | 33 | 17758 | 2279 |
PIGM,PIGN,JUP,SLC2A1,MGA,FAM192A,SUB1,TSPAN2,GPR87,IKBKB,MAD1L1,VAPB,CORO1A,NDUFA6,ZNRD1,SKIV2L,ZC4H2,TYW1,TSN,BCS1L,DLG4,EIF2A,POLG2,TCF7L2,RERE,HIF1A,MBTD1,INTS9,APAF1,BRD9,YEATS2,ECHDC1,SMG1 |
| 4.252e-02 | -3.16 | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDM_UP | 190 | 33 | 17758 | 2279 |
MYCBP2,SUPT6H,TNFRSF21,RTN4,OPA1,EEA1,MGA,PRKCH,UBR1,FTSJ3,CPSF3L,HNRNPM,LAMA4,VOPP1,PXN,GPCPD1,COTL1,PITPNB,KCNH2,MCM2,CPT1A,OSBPL1A,DDX3X,RARS,NSF,UBAP1,LUC7L3,SQLE,ZRANB2,FIS1,TAF12,BMI1,USP15 |
| 4.252e-02 | -3.16 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDM_DN | 190 | 33 | 17758 | 2279 |
SEC24D,SLC2A1,SEC16A,CMTM3,RSRC1,MAP2K3,ABL1,POLR3D,ARHGAP18,NISCH,ARHGAP1,MAP3K14,CPSF3L,PKNOX1,VPS37A,RREB1,RNMT,MEF2D,FAM126B,CAV1,METTL22,TJAP1,MGAT2,SMARCC1,ZNF330,CEBPZ,H2AFX,SVIL,USP20,DPP4,DNAJC12,CNOT6,ECHDC1 |
| 4.252e-02 | -3.16 | GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN | 190 | 33 | 17758 | 2279 |
PLRG1,RCAN1,C11orf54,MCM9,FDX1,KIAA1958,CD96,DECR1,NDUFV1,SCAF1,MARVELD2,KDELC1,ANP32B,FBXO31,ALDH18A1,DENND1A,FTSJ3,LONP1,CHD9,PRIM2,METTL15,SLC35D1,PDE2A,TRIM37,TBC1D2,WARS,RETSAT,ANXA2,DHCR7,RPS6KC1,SMYD3,MIPOL1,GCSH |
| 4.252e-02 | -3.16 | GSE17721_CTRL_VS_LPS_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_24H_BMDM_UP | 190 | 33 | 17758 | 2279 |
ASCC1,XPC,NECAP1,SSBP2,CLINT1,MFHAS1,PAG1,SPG21,UBR1,MARVELD2,RASSF3,CLCN6,SOCS6,CORO1A,MEIS3,ZNF124,LIMA1,USP42,ARID1A,GALK2,CPT1A,EIF3H,MLLT10,MRPL36,ANXA1,MGAT2,DDX3X,HLA-DMA,SVIL,DLX2,MACROD1,TSPAN5,SYNPO |
| 4.252e-02 | -3.16 | GSE1460_DP_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_DN | 190 | 33 | 17758 | 2279 |
ZNF516,KIF5A,ST6GAL1,PDE4B,SMAD7,PLOD1,ZFP36L1,PRKCA,INPP1,BMP6,SRPRB,LPIN2,RNF2,B3GNTL1,CD44,VCL,ADARB1,EVL,SIRT6,GNG7,MINA,ASAP3,ZNF512B,TPM4,CAMSAP2,COTL1,DDX60,STK10,SMAD3,ARL6IP5,PAM,TRAF3,GALNT10 |
| 4.252e-02 | -3.16 | GSE27786_LIN_NEG_VS_MONO_MAC_DN | MSigDB lists | GSE27786_LIN_NEG_VS_MONO_MAC_DN | 190 | 33 | 17758 | 2279 |
SLC37A3,BCKDK,AK2,CELSR3,PAFAH1B1,MYO7A,WDR26,CHAC1,TNKS1BP1,RAC3,SLC25A20,ATG3,TTC17,NDUFA6,HRG,ATP6V0D1,FMNL2,VPS13B,MCEE,ADAMTSL3,PPP1R21,ATOX1,RAP1GDS1,STK10,CXADR,ARID3B,PAM,NCOR1,NDUFS5,PDLIM5,PRKAR2A,SPOCK2,TRIM36 |
| 4.252e-02 | -3.16 | GSE17721_LPS_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDM_UP | 190 | 33 | 17758 | 2279 |
DCTN3,POLB,PAPD4,SEC24D,GRINA,TGFBR2,BIRC2,HSPA1A,UBL5,AHCYL2,PHC2,SLC38A5,TIMELESS,CMPK1,NRIP1,SEH1L,SF3A1,TSHZ1,BRD4,ANAPC13,RREB1,UPP1,WDPCP,C8orf33,HSPA1B,KIF16B,TRRAP,GALNT10,TBXA2R,PDLIM5,BMI1,DCAF5,TROVE2 |
| 4.252e-02 | -3.16 | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 190 | 33 | 17758 | 2279 |
PCNT,TAF1,PID1,DPM3,SSR4,PIBF1,AMBRA1,PRKCH,ABL1,RPS16,MYC,BANF1,ACOT11,TNPO3,RAN,YARS,TMEM120B,AKAP11,SERBP1,CASP8AP2,NAA38,HARS,ARID5B,MINA,CPT1A,MAT2A,STOML2,ZNF266,PTPN4,VPS13D,EIF2B3,TXN2,MORC2 |
| 4.252e-02 | -3.16 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | 190 | 33 | 17758 | 2279 |
TNIK,EGR1,UTP14A,NAT10,SLC25A12,KLHL18,FAM49A,PABPC4,SLC30A7,KRI1,POLR3D,NOP16,CCDC88C,RPL22L1,TRIM14,NT5E,RABEPK,PEA15,FOXN3,USP42,ARHGEF10,LRRC8A,RNH1,PTPN12,AKAP13,RERE,WARS,HLCS,ARL6IP5,POLR3E,TBL1X,POLR1C,KIF1B |
| 4.252e-02 | -3.16 | GSE17721_LPS_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDM_DN | 190 | 33 | 17758 | 2279 |
EPM2AIP1,EGR1,POLR1A,MFGE8,IGF2BP2,SLC9B2,TIMM10,FOXP1,CMTM3,NEDD4,RAP1A,MPHOSPH10,MYC,ZDHHC6,MET,PCK2,TSPAN14,PEA15,TFPI,ADSL,SCMH1,TBRG4,GALK2,ENC1,PWP1,FBXO21,LSM14A,FDPS,H2AFX,BPNT1,NRP1,NAPA,DDIT3 |
| 4.252e-02 | -3.16 | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDM_DN | 190 | 33 | 17758 | 2279 |
AK2,FN1,PAFAH1B1,DPF2,SPRYD7,TRPM6,PDE4B,MYNN,CLINT1,HSPA1A,SBDS,CD96,SHC1,UCHL5,IKBKB,ETF1,POLR1B,WNT16,TMEM120B,MARCKSL1,TOR1AIP2,CAV1,ZDHHC14,HSPA1B,TJAP1,IFT81,RAD18,PDLIM1,SERINC1,SNAP23,SEMA3C,ADK,USP15 |
| 4.252e-02 | -3.16 | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_DN | 190 | 33 | 17758 | 2279 |
NCOR2,NOMO3,KIF5A,RIBC2,CCNL2,SLC6A8,PRKD3,PHKA1,SCN1B,SEC24C,TTC3,CELF1,FBXO31,PRF1,CDC37,FGF9,GARS,CAMKK2,AKAP8L,IFNGR2,NR6A1,ZNF512B,TCEB3,KIAA0586,MARCKSL1,HIST1H2BL,ABCF1,SH3GL1,EHMT2,SYNGR2,HSPB8,COPS6,NAPA |
| 4.252e-02 | -3.16 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP | 190 | 33 | 17758 | 2279 |
SSH2,DNAJA4,ANKRD17,GPBP1L1,PRKAB2,RFX1,CSPP1,IQGAP2,CD96,SIPA1L3,KIAA0922,MEIS3,NT5E,KLRD1,ANTXR2,TCEB3,LRRC8A,CAMSAP2,PACS1,KRTCAP2,PEAK1,TMEM206,ARMC3,RERE,BTBD11,CHD3,STX1A,MBTD1,SLC4A7,MYOM2,GALNT10,TESC,TSPAN5 |
| 4.252e-02 | -3.16 | GSE11924_TFH_VS_TH17_CD4_TCELL_DN | MSigDB lists | GSE11924_TFH_VS_TH17_CD4_TCELL_DN | 190 | 33 | 17758 | 2279 |
BCCIP,ZNF706,PTCD2,NDUFA5,DNAJC2,WDR74,NAT10,MED18,APRT,NOP56,COMMD9,CTNNBL1,GMDS,HCFC2,POLR1E,SEH1L,RABEPK,SOBP,PDK1,SLC35D1,DKC1,YTHDF2,YIF1A,RETSAT,TMEM237,FAM206A,CSMD3,EME1,HEATR1,GGT7,LAMA5,HS2ST1,LPP |
| 4.261e-02 | -3.16 | ribonucleoside triphosphate metabolic process | biological process | GO:0009199 | 181 | 32 | 16441 | 2138 |
NDUFA5,AK2,ATP6V1A,NDUFB5,OLA1,CHCHD10,COX10,HSPA1A,NDUFS7,NDUFB3,CAD,AMPD3,NDUFV1,ENTPD5,ATP5G2,MYH3,NDUFA6,FXN,PFKFB4,BDNF,ITPA,LDHA,ATP6V0A1,SNCA,STOML2,ATP5D,HSPA1B,NME7,COQ9,SURF1,HK2,NDUFS5 |
| 4.265e-02 | -3.15 | CDC45 (cell division cycle 45) | protein interactions | 8318 | 34 | 9 | 16036 | 2270 |
MCM6,BRCA2,MCM10,POLA1,CDK4,ORC5,PDS5B,DTD1,RPS6KB2 |
| 4.265e-02 | -3.15 | API5 (apoptosis inhibitor 5) | protein interactions | 8539 | 34 | 9 | 16036 | 2270 |
OXSR1,NAA38,FGF2,MCM5,ADSL,XPNPEP1,MLH1,IMPDH2,TTI1 |
| 4.265e-02 | -3.15 | CSDE1 (cold shock domain containing E1, RNA binding) | protein interactions | 7812 | 34 | 9 | 16036 | 2270 |
SYNCRIP,JUP,COPS5,SEC24C,SIRT7,PCSK7,SUPT5H,PABPC1,PDE3A |
| 4.265e-02 | -3.15 | CLEC11A (C-type lectin domain family 11, member A) | protein interactions | 6320 | 34 | 9 | 16036 | 2270 |
MYCBP2,LAMC1,BIRC6,MAD1L1,BCOR,IKBIP,NUP214,BIRC2,VWA8 |
| 4.273e-02 | -3.15 | FA58C_2 | prosite domains | PS01286 | 16 | 5 | 11866 | 1504 |
NRP1,CNTNAP3,CNTNAP3B,MFGE8,DDR2 |
| 4.273e-02 | -3.15 | PI3_4_KINASE_3 | prosite domains | PS50290 | 16 | 5 | 11866 | 1504 |
ATM,TRRAP,PI4KB,PIK3CB,SMG1 |
| 4.276e-02 | -3.15 | V$BACH2_01 | MSigDB lists | V$BACH2_01 | 258 | 43 | 17758 | 2279 |
RELL2,SEC24D,FAM46B,TNXB,RTN4,LPCAT3,SPATS2,PHLDA2,ZNF827,ELL,MMP7,ADCK4,CDK6,MYB,PEA15,PPP1R9B,ATF4,TXLNG,BAZ2A,EIF3J,DLG4,PRDM1,NCDN,BTBD11,VDR,DYNC1H1,NOL10,DSC2,GADD45A,POLR3E,CSRNP1,HSPB8,MPV17,CSMD3,DIRAS1,ITGB4,BLMH,SYNPO,PRKAR2A,DDIT3,RAB30,TNRC6A,LPP |
| 4.281e-02 | -3.15 | aldosterone_producing | COSMIC cancer mutations | aldosterone_producing | 92 | 18 | 17775 | 2278 |
CYP24A1,RFC4,BRAF,NRAS,C1QTNF7,TRPM6,MEN1,EIF5B,NOP56,LRP1B,SIPA1L3,MED15,VPS13D,GREB1L,ZFP37,KDM5C,PDE9A,SOX6 |
| 4.286e-02 | -3.15 | Termination of translesion DNA synthesis | REACTOME pathways | R-HSA-5656169 | 30 | 8 | 8202 | 1117 |
RFC4,RFC3,POLE2,POLK,USP10,ISG15,UBC,RPA1 |
| 4.286e-02 | -3.15 | Pausing and recovery of Tat-mediated HIV elongation | REACTOME pathways | R-HSA-167238 | 30 | 8 | 8202 | 1117 |
ELL,SUPT4H1,CCNT1,CDK9,TCEB3,SUPT5H,NELFA,POLR2A |
| 4.286e-02 | -3.15 | Tat-mediated HIV elongation arrest and recovery | REACTOME pathways | R-HSA-167243 | 30 | 8 | 8202 | 1117 |
ELL,SUPT4H1,CCNT1,CDK9,TCEB3,SUPT5H,NELFA,POLR2A |
| 4.289e-02 | -3.15 | microtubule-based transport | biological process | GO:0010970 | 97 | 19 | 16441 | 2138 |
IFT57,PAFAH1B1,IFT43,MAP1S,OPA1,RHOT2,BLOC1S4,BLOC1S2,IFT81,ARHGAP21,BICD1,NME7,WDR35,HIF1A,DTNBP1,IFT140,DYNC2H1,KIF1B,MAPT |
| 4.295e-02 | -3.15 | actin cytoskeleton organization | biological process | GO:0030036 | 399 | 64 | 16441 | 2138 |
ARHGAP26,ACTG1,NF1,PAFAH1B1,PPARGC1B,ACTR3,TNXB,MYH9,COBLL1,ENAH,PLEK2,CORO6,RAC3,PPP1R9A,FLNB,ABL2,SHC1,DNAJB6,FMNL1,IKBKB,DTNBP1,MYH3,CORO1A,RAN,DBN1,FMNL3,EVL,LIMA1,PREX1,TMSB4X,CXADR,ARPC3,RHOU,TPM1,TTN,TNIK,SSH2,MINK1,CDC42EP2,OPHN1,ARFIP2,MON2,SPIRE1,MAD2L2,IQGAP2,ABL1,NEBL,TMSB10,NISCH,TTC17,AMOT,ACTR3B,FMNL2,MICAL3,PPP1R9B,OBSCN,PALLD,ANXA1,INF2,FSCN1,FAT1,IQSEC2,BRSK2,CORO2B |
| 4.295e-02 | -3.15 | ZHANG_RESPONSE_TO_CANTHARIDIN_DN | MSigDB lists | ZHANG_RESPONSE_TO_CANTHARIDIN_DN | 67 | 14 | 17758 | 2279 |
FARSA,ABCA3,ABCC4,NOP16,TRAP1,ATP5G2,SLK,MYC,CDK4,HARS2,AKAP13,MYB,NOP56,MTHFD1 |
| 4.298e-02 | -3.15 | Depolymerisation of the Nuclear Lamina | REACTOME pathways | R-HSA-4419969 | 15 | 5 | 8202 | 1117 |
PRKCA,LEMD3,LPIN2,LPIN1,TMPO |
| 4.302e-02 | -3.15 | DBN1 (drebrin 1) | protein interactions | 1627 | 61 | 14 | 16036 | 2270 |
USP7,DNMBP,JUP,FN1,ACD,NUP133,HOMER2,TPM4,TPM1,SUPT5H,BMI1,ZNF598,SPTAN1,MTHFD1 |
| 4.302e-02 | -3.15 | UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) | protein interactions | 7386 | 61 | 14 | 16036 | 2270 |
USP7,TSR1,NDUFV1,BCS1L,LGALS1,MPV17,RELB,XPNPEP1,VAPB,ABCC2,PHGDH,CYB5B,MPST,LYRM7 |
| 4.302e-02 | -3.15 | BANF1 (barrier to autointegration factor 1) | protein interactions | 8815 | 61 | 14 | 16036 | 2270 |
DNAJC2,SUB1,CUL4A,EHMT2,XPC,LUC7L3,BANF1,DPF2,SET,APTX,FBL,SOX4,HSPA1B,TMPO |
| 4.302e-02 | -3.15 | YEATS4 (YEATS domain containing 4) | protein interactions | 8089 | 61 | 14 | 16036 | 2270 |
UBTF,EP400,SRCAP,TRRAP,VPS72,JAZF1,MYC,MBTD1,VIM,FUS,FOSL2,KDM1A,MLLT10,SMARCB1 |
| 4.302e-02 | -3.15 | RUNX1T1 (runt-related transcription factor 1; translocated to, 1 (cyclin D-related)) | protein interactions | 862 | 61 | 14 | 16036 | 2270 |
VDR,TCF12,NCOR2,ID1,KPNA1,SPEN,TCF3,HDAC8,BRCA1,RBPJ,RUNX1,NCOR1,PRKAR2A,TAF9B |
| 4.302e-02 | -3.15 | UIMC1 (ubiquitin interaction motif containing 1) | protein interactions | 51720 | 61 | 14 | 16036 | 2270 |
SKIL,RFC4,BRE,RBBP8,SSU72,NR6A1,GLTSCR2,PYCRL,SHMT2,BRCA1,BRCC3,AMOT,DLST,UBC |
| 4.303e-02 | -3.15 | embryonic organ morphogenesis | biological process | GO:0048562 | 282 | 47 | 16441 | 2138 |
CHST11,IFT57,INSIG2,CELSR1,PAX2,MYO7A,ID2,TGFBR2,SLC39A1,CHD7,CEP290,MMP14,NDRG4,HYAL1,ZEB1,CCDC40,WNT16,MFAP2,MTHFD1,TSHZ1,SOBP,FGF9,MSX1,FZD3,WDPCP,SETD2,RDH10,GRHL3,RYR2,SATB2,ARID1A,MTHFD1L,FLVCR1,TCF7L2,FGFR1,SMAD3,INSIG1,HIF1A,HIPK2,TBX3,ARL13B,HOXA3,BMP4,DLX2,NRP1,MMP16,MEF2C |
| 4.303e-02 | -3.15 | ZFR (zinc finger RNA binding protein) | protein interactions | 51663 | 50 | 12 | 16036 | 2270 |
ADARB1,CUL7,UBAP2,S100A10,COPS5,TRA2A,SIRT7,PCED1B,RNF2,SERPINH1,BMI1,RPA1 |
| 4.303e-02 | -3.15 | DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha) | protein interactions | 1788 | 50 | 12 | 16036 | 2270 |
TERF2IP,PAF1,ZBTB17,USP7,EHMT2,MYC,EHMT1,CTR9,PRMT5,NRIP1,CDC73,POLR2A |
| 4.303e-02 | -3.15 | TXNDC9 (thioredoxin domain containing 9) | protein interactions | 10190 | 50 | 12 | 16036 | 2270 |
PEX7,SPAG9,FBXW4,ZCCHC8,CHD3,WDHD1,CEP126,IKBKAP,NUP214,PNMA1,VPS53,BAG1 |
| 4.303e-02 | -3.15 | RAB5B (RAB5B, member RAS oncogene family) | protein interactions | 5869 | 50 | 12 | 16036 | 2270 |
RAP1A,CUL7,RAB7A,LAGE3,RAP1B,SHMT2,RABAC1,DSP,REEP5,EEA1,CIAPIN1,SGSM3 |
| 4.303e-02 | -3.15 | POLR2L (polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa) | protein interactions | 5441 | 50 | 12 | 16036 | 2270 |
PHC2,BANP,POLR3D,L3MBTL3,INTS5,POLR1A,TCEB3,CCDC85B,POLR1B,POLR1C,NFKBIB,POLR2A |
| 4.308e-02 | -3.14 | V$SOX9_B1 | MSigDB lists | V$SOX9_B1 | 224 | 38 | 17758 | 2279 |
POLB,FN1,RHOBTB1,RBFOX2,PBX1,RTN4,NECAP1,ZIC2,SPATS2,FAM49A,PRKCH,NAV1,UBE3A,TSPAN2,FSIP2,SEC24C,CYB5D1,PDS5B,ETV1,TOP1,ZNF646,RREB1,ZFYVE1,TEAD1,ABCF2,PTPN12,SOX4,ZSCAN2,EHBP1,FGFR1,RERE,BSN,SLC39A14,ZBTB8OS,PER1,CCDC85B,PDE9A,KAT6A |
| 4.317e-02 | -3.14 | DAG/PE-bd | interpro domains | IPR020454 | 21 | 6 | 18293 | 2341 |
PRKCH,PRKCE,CHN1,PRKD3,BRAF,PRKCA |
| 4.321e-02 | -3.14 | XY body | cellular component | GO:0001741 | 16 | 5 | 17570 | 2233 |
SMARCC1,RAD18,BIRC2,H2AFX,SMARCB1 |
| 4.321e-02 | -3.14 | eukaryotic translation initiation factor 3 complex | cellular component | GO:0005852 | 16 | 5 | 17570 | 2233 |
DDX3X,EIF3C,EIF3J,COPS5,EIF3H |
| 4.322e-02 | -3.14 | FRASOR_TAMOXIFEN_RESPONSE_UP | MSigDB lists | FRASOR_TAMOXIFEN_RESPONSE_UP | 49 | 11 | 17758 | 2279 |
EFNB2,LSS,SOCS1,STAG1,RDX,PTPRG,BHLHE40,CD44,PRPS1,RAB30,SLC25A1 |
| 4.322e-02 | -3.14 | APPIERTO_RESPONSE_TO_FENRETINIDE_DN | MSigDB lists | APPIERTO_RESPONSE_TO_FENRETINIDE_DN | 49 | 11 | 17758 | 2279 |
ASNS,PSAT1,SIGMAR1,FMNL1,BANF1,SET,LDHA,C11orf49,CCNDBP1,IFITM2,CYB5B |
| 4.322e-02 | -3.14 | NUCLEAR_MEMBRANE | MSigDB lists | NUCLEAR_MEMBRANE | 49 | 11 | 17758 | 2279 |
RANBP2,RETSAT,KPNA1,KPNA3,NUP133,LEMD3,RANGAP1,XPO7,NUP214,DHCR7,NUP160 |
| 4.322e-02 | -3.14 | GCTGAGT,MIR-512-5P | MSigDB lists | GCTGAGT,MIR-512-5P | 49 | 11 | 17758 | 2279 |
CHD9,BAZ2A,ATRX,USP20,MBD6,FNBP1L,PDSS2,UBR5,RAB10,PHF6,SRPK2 |
| 4.322e-02 | -3.14 | CGGAARNGGCNG_UNKNOWN | MSigDB lists | CGGAARNGGCNG_UNKNOWN | 49 | 11 | 17758 | 2279 |
CHMP2A,EGR1,GTF2A1,PAX2,GLYR1,XPO5,CTR9,UMPS,IGF2BP2,MARCH6,CDC37 |
| 4.322e-02 | -3.14 | CHEN_NEUROBLASTOMA_COPY_NUMBER_GAINS | MSigDB lists | CHEN_NEUROBLASTOMA_COPY_NUMBER_GAINS | 49 | 11 | 17758 | 2279 |
RNF141,ZFHX3,TSSC1,NKD2,ACP1,GALK2,ODC1,BRD9,GABPB2,TRIP13,TNRC6A |
| 4.322e-02 | -3.14 | GERHOLD_ADIPOGENESIS_UP | MSigDB lists | GERHOLD_ADIPOGENESIS_UP | 49 | 11 | 17758 | 2279 |
PLIN2,ACADS,ANAPC1,GADD45A,PPARG,CFD,LDHA,MCL1,GPAM,PPA1,DDIT3 |
| 4.325e-02 | -3.14 | cytoskeleton organization | biological process | GO:0007010 | 860 | 129 | 16441 | 2138 |
ARHGAP26,CGN,CUL7,ACTG1,NF1,PPARGC1B,TUBE1,ENAH,RAC3,BIRC2,DST,ABL2,NEK6,NCKIPSD,XRCC2,MYH3,RAN,CEP135,SEH1L,DBN1,FMNL3,LIMA1,KATNAL1,CAMSAP2,BRCA1,CAV1,SON,TMSB4X,CXADR,ARPC3,RHOU,BRCA2,CHD3,TPM1,TTN,JUP,CDC42EP2,OPHN1,DNAH1,SPIRE1,NAV1,FMNL2,KRT20,HAUS6,OBSCN,MAP7D1,DYNC1H1,ATXN7,BICD1,FSCN1,FAT1,SDCCAG8,SLC16A1,KIAA0196,NCOR1,IQSEC2,BRSK2,ARHGAP10,PCNT,PAFAH1B1,PSTPIP2,ACTR3,TNXB,TBCCD1,COBLL1,MYH9,PLEK2,CORO6,PIBF1,SEMA6A,PPP1R9A,FLNB,BLOC1S2,SHC1,FMNL1,DNAJB6,IKBKB,DTNBP1,CCDC40,CEP63,CORO1A,PHLDB2,EVL,WDPCP,ASUN,PREX1,ARHGEF10,VIM,DSP,ARMC4,ARC,MID1,LAMA5,MAPT,PARD3,TNIK,SSH2,KIZ,MINK1,MAP1S,ARFIP2,MON2,MLH1,CEP126,CSNK1A1,MAD2L2,IQGAP2,ABL1,NEBL,TMSB10,NISCH,TTC17,AMOT,ACTR3B,MICAL3,PPP1R9B,TTLL5,PXN,TEX14,PTK2,PALLD,ANXA1,INF2,GADD45A,BCAS3,SVIL,BRWD3,ZAK,CORO2B |
| 4.339e-02 | -3.14 | CAGGTCC,MIR-492 | MSigDB lists | CAGGTCC,MIR-492 | 61 | 13 | 17758 | 2279 |
DBN1,SERF2,SMARCC1,SMARCAD1,PURB,MYH9,PCNXL2,C11orf49,AKAP13,SH3PXD2A,MAT2A,AMBRA1,NCDN |
| 4.344e-02 | -3.14 | skin-back-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,ZCCHC8,LSM14A,ERC1,PPFIBP1 |
| 4.344e-02 | -3.14 | skin-buttock-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,LSM14A,ZCCHC8,ERC1,PPFIBP1 |
| 4.344e-02 | -3.14 | skin-chest-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-chest-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,LSM14A,ZCCHC8,ERC1,PPFIBP1 |
| 4.344e-02 | -3.14 | skin-upper_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,LSM14A,ZCCHC8,ERC1,PPFIBP1 |
| 4.344e-02 | -3.14 | skin-leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-leg-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,LSM14A,ZCCHC8,ERC1,PPFIBP1 |
| 4.344e-02 | -3.14 | skin-breast-malignant_melanoma | COSMIC cancer mutations | skin-breast-malignant_melanoma | 21 | 6 | 17775 | 2278 |
MGAT2,TMEM63C,BRAF,NRAS,KRTCAP2,NF1 |
| 4.344e-02 | -3.14 | skin-foot-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-foot-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,LSM14A,ZCCHC8,ERC1,PPFIBP1 |
| 4.344e-02 | -3.14 | skin-shoulder-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-Spitz | 21 | 6 | 17775 | 2278 |
BRAF,NRAS,LSM14A,ZCCHC8,ERC1,PPFIBP1 |
| 4.346e-02 | -3.14 | RBM8A (RNA binding motif protein 8A) | protein interactions | 9939 | 78 | 17 | 16036 | 2270 |
SEPHS2,DPH1,SLK,SMG7,ZFP36L1,TTI1,CIAPIN1,TOE1,RPS16,RNF2,UPF2,NCBP2,SRRM2,PABPC1,HNRNPM,SMG1,SRPK2 |
| 4.346e-02 | -3.14 | COPB1 (coatomer protein complex subunit beta 1) | protein interactions | 1315 | 78 | 17 | 16036 | 2270 |
RANBP6,ADAM19,ID1,FN1,TLE3,SIRT7,TRIM37,UBC,CAD,PRKCE,VPS18,KPNA3,FMNL1,TANK,SHMT2,RNF2,HSD17B12 |
| 4.352e-02 | -3.13 | ELVIDGE_HYPOXIA_BY_DMOG_DN | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_DN | 55 | 12 | 17758 | 2279 |
SRM,SOBP,URB2,PYCRL,LPCAT3,SLC29A1,PUS1,CORO1A,SLC25A44,ODC1,NAPA,TAF9B |
| 4.352e-02 | -3.13 | PID_TGFBR_PATHWAY | MSigDB lists | PID_TGFBR_PATHWAY | 55 | 12 | 17758 | 2279 |
SMAD3,FKBP1A,SKIL,SHC1,SMAD7,PPP2R2A,RNF111,RPS6KB1,CAV1,EIF2A,TGFB2,TGFBR2 |
| 4.352e-02 | -3.13 | SNRPB (small nuclear ribonucleoprotein polypeptides B and B1) | protein interactions | 6628 | 107 | 22 | 16036 | 2270 |
SKIV2L,BANP,PRAME,CUL7,CUL4A,FN1,TFIP11,LGALS1,SF3A3,GIGYF2,CLNS1A,RPA1,GEMIN5,DYNC1H1,L3MBTL3,COPS5,CUL2,GEMIN4,PRMT5,PNMA1,SRPK2,RPS6KB2 |
| 4.352e-02 | -3.13 | PIAS1 (protein inhibitor of activated STAT 1) | protein interactions | 8554 | 107 | 22 | 16036 | 2270 |
ZNF76,MSX1,PPARG,PPARGC1B,SMAD7,CSNK2A1,SUMO3,ATXN1,SATB2,PRDM1,BRCA1,PTK2,SPOP,SKIL,ATXN7,SUFU,SREBF2,NCOR1,NR2F2,SERBP1,CASP8AP2,MYB |
| 4.352e-02 | -3.13 | NDRG1 (N-myc downstream regulated 1) | protein interactions | 10397 | 107 | 22 | 16036 | 2270 |
ACTG1,TLE3,HSPA5,LDHA,PPP2R2A,MLH1,DLST,TARS,CLNS1A,PGD,NAMPT,ZNF155,SPAG9,RPS16,GART,G6PD,CUL2,ANXA5,SHMT2,CNDP2,IGBP1,PABPC1 |
| 4.354e-02 | -3.13 | Height(PMID:18391951) | GWAS genes | Height(PMID:18391951) | 28 | 9 | 2389 | 419 |
HMGA2,DNM3,LIN28B,L3MBTL3,TNXB,UQCC1,ADGRG6,CDK6,PDE3A |
| 4.357e-02 | -3.13 | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_UP | 157 | 28 | 17758 | 2279 |
USE1,SERINC5,PRPF38B,MAP2K5,COL5A2,CNTNAP3,GLTSCR2,GPBP1L1,TCF3,DDX19A,RAPGEF4,ZNF280C,RSL1D1,NUP43,SLC26A11,CASC1,RSPRY1,IFT81,RPS16,KDM4B,LUC7L3,ZNF81,ASB3,ZNF85,ANP32B,EME1,ANGPT2,NOM1 |
| 4.358e-02 | -3.13 | CSTA (cystatin A (stefin A)) | protein interactions | 1475 | 24 | 7 | 16036 | 2270 |
EVPL,CSTA,DSP,UCHL5,TCF3,CUL2,METTL23 |
| 4.358e-02 | -3.13 | C20orf24 (chromosome 20 open reading frame 24) | protein interactions | 55969 | 24 | 7 | 16036 | 2270 |
DYNC1H1,SLC25A12,DDX3X,TNPO3,XPO7,SSR4,IPO11 |
| 4.358e-02 | -3.13 | TNRC6A (trinucleotide repeat containing 6A) | protein interactions | 27327 | 24 | 7 | 16036 | 2270 |
CNOT6,UBR5,PABPC1,TRIP13,AGO3,AGO2,UBC |
| 4.358e-02 | -3.13 | SNX12 (sorting nexin 12) | protein interactions | 29934 | 24 | 7 | 16036 | 2270 |
RTN4,APRT,NME1-NME2,AHCYL1,IGBP1,PPIL3,CLNS1A |
| 4.358e-02 | -3.13 | PHF20L1 (PHD finger protein 20-like 1) | protein interactions | 51105 | 24 | 7 | 16036 | 2270 |
KAT8,GATAD2B,CHD3,MBD2,CASP10,KDM1A,UBC |
| 4.358e-02 | -3.13 | OTUD6B (OTU domain containing 6B) | protein interactions | 51633 | 24 | 7 | 16036 | 2270 |
MYH9,ASCC3,PTK2,APEX1,CHD3,SEC24C,HDDC2 |
| 4.358e-02 | -3.13 | DDX19A (DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A) | protein interactions | 55308 | 24 | 7 | 16036 | 2270 |
LIG4,MIF4GD,NUP214,SMARCAD1,PABPC1,CTIF,SPTAN1 |
| 4.358e-02 | -3.13 | RWDD2B (RWD domain containing 2B) | protein interactions | 10069 | 24 | 7 | 16036 | 2270 |
PHC2,KIAA1958,BRCA1,PDLIM5,DCAF5,DENR,SRPK2 |
| 4.358e-02 | -3.13 | TADA2B (transcriptional adaptor 2B) | protein interactions | 93624 | 24 | 7 | 16036 | 2270 |
TERF2IP,TADA3,TRRAP,SUPT20H,TAF12,TERF2,TAF9B |
| 4.358e-02 | -3.13 | SEH1L (SEH1-like nucleoporin) | protein interactions | 81929 | 24 | 7 | 16036 | 2270 |
ATP6V0A1,NUP43,NUP160,NUP133,COPS5,DCTN4,RPA1 |
| 4.358e-02 | -3.13 | TOM1L2 (target of myb1 like 2 membrane trafficking protein) | protein interactions | 146691 | 24 | 7 | 16036 | 2270 |
SERPINH1,AHCYL1,IGBP1,AGL,UBC,NEDD4,LAGE3 |
| 4.360e-02 | -3.13 | RNF168 (ring finger protein 168, E3 ubiquitin protein ligase) | protein interactions | 165918 | 29 | 8 | 16036 | 2270 |
HERC2,TP53BP1,JMJD1C,H2AFX,UBR5,UBE2E1,UBC,KDM1A |
| 4.360e-02 | -3.13 | SWAP70 (SWAP switching B-cell complex 70kDa subunit) | protein interactions | 23075 | 29 | 8 | 16036 | 2270 |
GART,CELSR3,SET,ASUN,RAPGEF4,ZRANB2,JMJD6,SUPT5H |
| 4.360e-02 | -3.13 | HTR6 (5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled) | protein interactions | 3362 | 29 | 8 | 16036 | 2270 |
RANBP6,NSF,NF1,COPS5,ATM,TTI1,NCDN,SMG1 |
| 4.360e-02 | -3.13 | NUCB1 (nucleobindin 1) | protein interactions | 4924 | 29 | 8 | 16036 | 2270 |
METTL1,MYC,SET,KLC4,XPNPEP1,PTGS1,WARS,GNAI1 |
| 4.360e-02 | -3.13 | USP42 (ubiquitin specific peptidase 42) | protein interactions | 84132 | 29 | 8 | 16036 | 2270 |
HERC2,KPNA3,PLRG1,WDR18,BMS1,AHCYL1,AMOT,SRRM2 |
| 4.360e-02 | -3.13 | ARPC5 (actin related protein 2/3 complex subunit 5) | protein interactions | 10092 | 29 | 8 | 16036 | 2270 |
METTL1,ACTR3,ANP32B,ACTR3B,EIF3H,ARPC3,TOM1L1,SH3GL1 |
| 4.360e-02 | -3.13 | NSD1 (nuclear receptor binding SET domain protein 1) | protein interactions | 64324 | 29 | 8 | 16036 | 2270 |
VDR,PPARG,NR6A1,ATRX,TNFRSF21,SIRT7,NR2F2,NR2F1 |
| 4.360e-02 | -3.13 | KMT2B (lysine (K)-specific methyltransferase 2B) | protein interactions | 9757 | 29 | 8 | 16036 | 2270 |
SMAD3,ANXA7,ZNF512B,RAP1B,ATXN1,NREP,ANXA1,SMARCB1 |
| 4.360e-02 | -3.13 | ORC6 (origin recognition complex subunit 6) | protein interactions | 23594 | 29 | 8 | 16036 | 2270 |
MCM6,MCM5,PSPC1,ORC5,DBF4,MCM2,RPA1,TERF2 |
| 4.360e-02 | -3.13 | TNFRSF1B (tumor necrosis factor receptor superfamily, member 1B) | protein interactions | 7133 | 29 | 8 | 16036 | 2270 |
TNFRSF1A,FANCD2,RIPK1,TRAF3,ASB3,CAV1,TRIM37,CSNK1A1 |
| 4.360e-02 | -3.13 | RAB8B (RAB8B, member RAS oncogene family) | protein interactions | 51762 | 29 | 8 | 16036 | 2270 |
RAP1A,PXN,TUBA1A,JUP,RAB7A,HSD17B10,RAP1B,VIM |
| 4.360e-02 | -3.13 | LAPTM5 (lysosomal protein transmembrane 5) | protein interactions | 7805 | 29 | 8 | 16036 | 2270 |
ANKRD13A,EPN2,TOM1L2,KRT7,HERC1,DISP1,NEDD4,UBC |
| 4.364e-02 | -3.13 | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 177 | 31 | 17758 | 2279 |
MCEE,VOPP1,SEC24A,FAM98A,ARNTL2,DMGDH,GARS,GNG7,TPM4,KIF15,C11orf80,COBLL1,MARS,EFHC1,CCDC113,CAV1,SPATS2,MCM2,CLINT1,MAN1A1,SRPRB,SLC39A14,SUB1,ALG5,CCDC167,CBWD1,HIBCH,ASB3,TRIP13,CEP128,MTHFD1 |
| 4.369e-02 | -3.13 | BIOCARTA_NOS1_PATHWAY | MSigDB lists | BIOCARTA_NOS1_PATHWAY | 21 | 6 | 17758 | 2279 |
DLG4,PPP3CC,PRKCA,GRIN2C,PRKAR2A,PRKACB |
| 4.369e-02 | -3.13 | chr18q22 | MSigDB lists | chr18q22 | 21 | 6 | 17758 | 2279 |
TSHZ1,RTTN,CNDP2,CD226,ZNF236,SOCS6 |
| 4.369e-02 | -3.13 | INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | INTRACELLULAR_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 21 | 6 | 17758 | 2279 |
MED24,MED16,ARID1A,UBR5,RBFOX2,PPARGC1B |
| 4.369e-02 | -3.13 | CELL_DIVISION | MSigDB lists | CELL_DIVISION | 21 | 6 | 17758 | 2279 |
MYH9,DCTN3,BRCA2,SEPT5,TGFB2,PARD3 |
| 4.369e-02 | -3.13 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | MSigDB lists | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | 21 | 6 | 17758 | 2279 |
ANAPC1,CDC16,ANAPC4,UBE2E1,ANAPC11,ANAPC10 |
| 4.369e-02 | -3.13 | COFACTOR_BIOSYNTHETIC_PROCESS | MSigDB lists | COFACTOR_BIOSYNTHETIC_PROCESS | 21 | 6 | 17758 | 2279 |
ME1,ALAD,COX10,COQ3,PDSS2,CPOX |
| 4.369e-02 | -3.13 | FOURNIER_ACINAR_DEVELOPMENT_EARLY_UP | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_EARLY_UP | 21 | 6 | 17758 | 2279 |
PID1,SUCLG2,SRCAP,FOSL2,MACROD1,EGR1 |
| 4.369e-02 | -3.13 | MITOCHONDRIAL_TRANSPORT | MSigDB lists | MITOCHONDRIAL_TRANSPORT | 21 | 6 | 17758 | 2279 |
TAMM41,TIMM17A,TOMM34,MFN2,SLC25A1,TIMM44 |
| 4.369e-02 | -3.13 | FERRARI_RESPONSE_TO_FENRETINIDE_UP | MSigDB lists | FERRARI_RESPONSE_TO_FENRETINIDE_UP | 21 | 6 | 17758 | 2279 |
SEMA3C,BHLHE40,NRIP1,HERPUD1,DDIT3,DDIT4 |
| 4.369e-02 | -3.13 | SPLICEOSOME_ASSEMBLY | MSigDB lists | SPLICEOSOME_ASSEMBLY | 21 | 6 | 17758 | 2279 |
SCAF11,SF3A3,CELF1,SFSWAP,SF3A1,SRPK2 |
| 4.371e-02 | -3.13 | muscle hypertrophy | biological process | GO:0014896 | 26 | 7 | 16441 | 2138 |
RYR2,CAMK2D,TTN,CAMTA2,GATA6,PDLIM5,MEF2C |
| 4.373e-02 | -3.13 | positive regulation of DNA repair | biological process | GO:0045739 | 37 | 9 | 16441 | 2138 |
BRE,APEX1,TMEM161A,NPAS2,EYA3,H2AFX,BRCA1,BRCC3,SPIDR |
| 4.373e-02 | -3.13 | porphyrin-containing compound metabolic process | biological process | GO:0006778 | 37 | 9 | 16441 | 2138 |
ALAD,CPOX,UROD,BDH2,HMBS,HMOX2,COX10,FXN,TMEM14C |
| 4.395e-02 | -3.12 | regulation of binding | biological process | GO:0051098 | 262 | 44 | 16441 | 2138 |
HMGA2,ID1,CAMK1,ID2,RSF1,SIRT2,CSNK1A1,MAD2L2,KDM1A,SKI,ABL2,FKBP1A,ABL1,S100A10,ACD,RAN,CARM1,ZNF675,BRD4,MSX1,HSPA5,TEX14,SMARCD3,PACS1,CAV1,MEN1,HERPUD1,TCF7L2,DOT1L,SMAD3,TRIB3,MSX2,NSD1,SPAG9,ADNP,CDK9,HIPK2,ZFP90,ANXA2,BMP4,NRP1,DDIT3,STK4,MEF2C |
| 4.397e-02 | -3.12 | regulation of receptor activity | biological process | GO:0010469 | 91 | 18 | 16441 | 2138 |
KLHL24,MINK1,PPARGC1B,DLG4,MED16,SRA1,PRKCE,BICD1,SHC1,CNIH3,ZFYVE28,BUD31,SOCS4,NLGN3,ANXA2,ARC,ERRFI1,MEF2C |
| 4.397e-02 | -3.12 | regulation of macroautophagy | biological process | GO:0016241 | 91 | 18 | 16441 | 2138 |
ZBTB17,WDR75,TRIM13,FEZ2,WDFY3,RAB7A,SUPT5H,PIP4K2A,POLR3A,AMBRA1,USP36,RPL28,SREBF2,HIF1A,WAC,ATG7,LRSAM1,HTRA2 |
| 4.399e-02 | -3.12 | VHL (von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase) | protein interactions | 7428 | 285 | 51 | 16036 | 2270 |
FN1,SLC2A1,CSNK2A1,APRT,PDCD5,UBR5,HSPA1A,HNRNPA3,HNRNPLL,PRKCH,P3H1,SOCS1,ATXN2,MYC,VAPB,MSH4,CD44,PRMT3,HNRNPM,SLC3A2,TUBA1A,KIRREL2,RB1CC1,HSPA5,JMJD1C,TCEB3,ZNF512B,PCMT1,IMPDH2,HIST1H2BL,SON,TARS,POLR2A,ZNF197,UBC,DDX3X,IREB2,MYBBP1A,HNRNPR,HIF1A,FSCN1,KLF4,DNAJA3,COPS5,CUL2,USP20,ATM,CLU,PTPN14,PARD3,LPP |
| 4.401e-02 | -3.12 | Y_phosphatase | pfam domains | PF00102 | 37 | 9 | 16629 | 2165 |
PTPN2,PTPRA,PTPRM,PTPN4,PTPN12,PTP4A2,PTPRG,PTPN14,PTPRK |
| 4.410e-02 | -3.12 | DM10 | prosite domains | PS51336 | 3 | 2 | 11866 | 1504 |
EFHC1,NME7 |
| 4.410e-02 | -3.12 | GHMP_KINASES_ATP | prosite domains | PS00627 | 3 | 2 | 11866 | 1504 |
MVK,GALK2 |
| 4.410e-02 | -3.12 | GART | prosite domains | PS00373 | 3 | 2 | 11866 | 1504 |
GART,ALDH1L2 |
| 4.410e-02 | -3.12 | SAM_MT_TRM10 | prosite domains | PS51675 | 3 | 2 | 11866 | 1504 |
TRMT10B,TRMT10A |
| 4.410e-02 | -3.12 | DFDF | prosite domains | PS51512 | 3 | 2 | 11866 | 1504 |
LSM14A,EDC3 |
| 4.410e-02 | -3.12 | ADOHCYASE_2 | prosite domains | PS00739 | 3 | 2 | 11866 | 1504 |
AHCYL1,AHCYL2 |
| 4.410e-02 | -3.12 | COPPER_AMINE_OXID_2 | prosite domains | PS01165 | 3 | 2 | 11866 | 1504 |
AOC3,AOC2 |
| 4.410e-02 | -3.12 | CAVEOLIN | prosite domains | PS01210 | 3 | 2 | 11866 | 1504 |
CAV1,CAV2 |
| 4.410e-02 | -3.12 | P5CR | prosite domains | PS00521 | 3 | 2 | 11866 | 1504 |
PYCRL,PYCR1 |
| 4.410e-02 | -3.12 | RNA_POL_BETA | prosite domains | PS01166 | 3 | 2 | 11866 | 1504 |
POLR3B,POLR1B |
| 4.410e-02 | -3.12 | COPPER_AMINE_OXID_1 | prosite domains | PS01164 | 3 | 2 | 11866 | 1504 |
AOC3,AOC2 |
| 4.410e-02 | -3.12 | ADOHCYASE_1 | prosite domains | PS00738 | 3 | 2 | 11866 | 1504 |
AHCYL1,AHCYL2 |
| 4.410e-02 | -3.12 | AA_TRNA_LIGASE_II_ALA | prosite domains | PS50860 | 3 | 2 | 11866 | 1504 |
AARS,AARS2 |
| 4.410e-02 | -3.12 | regulation of catabolic process | biological process | GO:0009894 | 703 | 107 | 16441 | 2138 |
USP7,MYCBP2,FEZ2,RCHY1,CSNK2A1,SIRT2,AMBRA1,ABL2,TMEM150C,ANAPC1,NEK6,SREBF2,GRIN2C,UCHL5,WAC,ANAPC11,ANAPC10,MAD1L1,FHIT,MET,HTRA2,KAT8,ZBTB17,TRIM13,SIRT6,RAB7A,SUMO3,CAV1,EDEM2,ODC1,USP36,SNCA,FBXL5,SMAD3,ZC3H12A,CDC16,SMARCC1,NSMCE2,SOCS4,ATG7,ADAM9,SCARB1,CLU,ANXA2,USP11,UQCC2,MAPT,USP15,BANP,WDR75,FOXO1,TAF1,UBXN1,AGO2,NKD2,OPHN1,SMAD7,TRIM22,SOGA1,PIP4K2A,PSMF1,RHBDD1,MAD2L2,NEDD4,DDIT4,PRKCE,ABL1,RNF40,UBE3A,ENTPD5,RDX,LRSAM1,LPCAT1,PABPC1,WDFY3,USP49,RB1CC1,USP42,DHX34,TEX14,PSMA1,USP10,PTK2,SUPT5H,UBE2K,CPT1A,PDE3B,PIK3CB,HERPUD1,POLR3A,UBC,ARIH2,UBE2E1,IRS1,TRIB3,KLHL22,RPL28,NSF,HIF1A,HERC1,RRAGA,USP20,ATM,APAF1,NCOR1,BRSK2,ANAPC4 |
| 4.416e-02 | -3.12 | epithelial tube morphogenesis | biological process | GO:0060562 | 303 | 50 | 16441 | 2138 |
EFNB2,IFT57,DLL4,CELSR1,LUZP1,PAX2,MKS1,PBX1,ENAH,ZIC2,LIAS,SEMA3E,TGFBR2,SKI,MYC,MMP14,NDRG4,TIMELESS,CCDC40,MET,CD44,PRKACB,MTHFD1,DEAF1,PXN,FGF2,FZD3,SETD2,RDH10,GRHL3,RYR2,ARID1A,MTHFD1L,SOX4,TCTN1,GZF1,VDR,SMAD3,MSX2,HIF1A,TBX3,ARL13B,RBPJ,BMP4,APAF1,NRP1,LAMA5,STK4,HS2ST1,MEF2C |
| 4.422e-02 | -3.12 | positive regulation of cell size | biological process | GO:0045793 | 11 | 4 | 16441 | 2138 |
TMEM123,AMOT,RB1CC1,CDK4 |
| 4.422e-02 | -3.12 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902237 | 11 | 4 | 16441 | 2138 |
PTPN2,PMAIP1,DDIT3,SPOP |
| 4.422e-02 | -3.12 | positive regulation of neurotransmitter secretion | biological process | GO:0001956 | 11 | 4 | 16441 | 2138 |
STX1A,UNC13A,SNCA,DTNBP1 |
| 4.422e-02 | -3.12 | cellular response to epinephrine stimulus | biological process | GO:0071872 | 11 | 4 | 16441 | 2138 |
RYR2,SIRT2,PDE4B,SNCA |
| 4.422e-02 | -3.12 | bundle of His cell to Purkinje myocyte communication | biological process | GO:0086069 | 11 | 4 | 16441 | 2138 |
DSC2,JUP,DSP,DSG2 |
| 4.422e-02 | -3.12 | negative regulation of JAK-STAT cascade | biological process | GO:0046426 | 11 | 4 | 16441 | 2138 |
PTPN2,CAV1,SOCS1,PIBF1 |
| 4.422e-02 | -3.12 | tetrahydrofolate interconversion | biological process | GO:0035999 | 11 | 4 | 16441 | 2138 |
SHMT2,MTHFD1L,MTHFD2L,MTHFD1 |
| 4.422e-02 | -3.12 | RNA interference | biological process | GO:0016246 | 11 | 4 | 16441 | 2138 |
CELF1,DROSHA,AGO3,AGO2 |
| 4.422e-02 | -3.12 | establishment of mitochondrion localization | biological process | GO:0051654 | 11 | 4 | 16441 | 2138 |
MAP1S,RHOT2,KIF1B,MAPT |
| 4.424e-02 | -3.12 | MODULE_206 | MSigDB lists | MODULE_206 | 144 | 26 | 17758 | 2279 |
VIPR1,WDR36,CLDN15,PRDX6,TRIO,R3HDM1,USP10,SLC25A12,ADAMTS6,ARID1A,MCM2,ST3GAL6,MBNL1,RPAIN,ZNF251,LPIN1,PWP1,SEC24C,CUL2,ANKRD11,PIGG,KDELC1,RAN,TOMM34,SLC16A10,HMGCR |
| 4.431e-02 | -3.12 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1433 | 205 | 17775 | 2278 |
ARHGAP26,POLB,THOC5,NF1,PRKAB2,HECTD3,CSNK2A1,HLTF,PRKCA,LPAR3,UBR5,BIRC2,MAP2K3,WNT2B,GIPR,SMARCB1,ABL2,EXOC1,RAP1A,PMAIP1,JAZF1,XRCC2,ANAPC11,NCKIPSD,MAD1L1,RELB,JOSD1,RAN,ETV1,ZMYM2,OGG1,CDK6,PRKACB,CDC37,DBN1,RBCK1,NRAS,PPARG,CDK4,KSR2,CAV1,BRCA1,SGK2,MLLT10,SH3GL1,SPOP,RHOU,TCF7L1,BRCA2,SUFU,RAD18,SH3RF1,PER1,SOCS4,TNFRSF1A,RAD51B,DIRAS1,RUNX1,CCNB1IP1,MAGI1,NRP1,COPS6,FIP1L1,ZNF598,USP15,LPP,MEF2C,CARS,FBXO45,FOXO1,CELSR1,LAMTOR3,MAPK8IP3,PIK3R4,PCSK7,TGFBR2,CDC73,PRKCE,ELL,UBE3A,USPL1,ATIC,MYC,GTF2H1,WNT16,PEA15,MSI2,SIK3,GTF2H3,PDE4A,USP49,PRDM16,TLE3,RAP1B,LIG4,USP10,TRIM37,USP46,TCF7L2,IRS1,SPAG9,PALB2,SQLE,DDX10,PRKAR2A,MAP2K4,TCF12,USP7,SPRED2,DLL4,ABCA3,CYLD,NTSR1,DDR2,RIPK1,PBX1,PPP2R2A,FOSL2,LTB4R,RADIL,FLNB,SBDS,JAG1,SHC1,KDM2A,SOCS1,UCHL5,IKBKB,SOCS6,RNF2,TTC3,MSH4,MET,KMT2A,CDK12,CASP10,MAML3,PMS1,BRD4,PDK1,STAMBP,PARP2,MARCH6,MEF2D,NUP214,STK10,ERC1,EIF3H,FGFR1,USP36,EXO1,RANBP2,RBBP8,COPS5,ACP1,RPS6KB1,TRAF3,FUS,USP11,BRCC3,SEPT5,MUTYH,SMG1,TRIM36,BCKDK,BRAF,XPC,TCF3,MLH1,TGFB2,CSNK1A1,FOXO3,NEDD4,MAD2L2,ABL1,LTN1,FBXL19,RPS6KB2,TOP1,FGF9,PXN,APEX1,ADAMTSL3,FGF2,FZD3,TEX14,RAP1GDS1,ARHGEF12,MEN1,KLF6,PIK3CB,DKK1,ZRANB3,HERC1,SET,MSH3,DNAJC12,USP20,ATM,RBPJ,BMP4,NFKBIB,RABEP1,DDIT3,STK4 |
| 4.434e-02 | -3.12 | laminin-10 complex | cellular component | GO:0043259 | 3 | 2 | 17570 | 2233 |
LAMC1,LAMA5 |
| 4.434e-02 | -3.12 | Ski complex | cellular component | GO:0055087 | 3 | 2 | 17570 | 2233 |
SKIV2L,WDR61 |
| 4.434e-02 | -3.12 | NatC complex | cellular component | GO:0031417 | 3 | 2 | 17570 | 2233 |
NAA38,NAA35 |
| 4.434e-02 | -3.12 | catenin-TCF7L2 complex | cellular component | GO:0071664 | 3 | 2 | 17570 | 2233 |
JUP,TCF7L2 |
| 4.434e-02 | -3.12 | synaptobrevin 2-SNAP-25-syntaxin-1a complex | cellular component | GO:0070044 | 3 | 2 | 17570 | 2233 |
NAPA,STX1A |
| 4.434e-02 | -3.12 | Atg12-Atg5-Atg16 complex | cellular component | GO:0034274 | 3 | 2 | 17570 | 2233 |
ATG12,WDFY3 |
| 4.434e-02 | -3.12 | tubulin complex | cellular component | GO:0045298 | 3 | 2 | 17570 | 2233 |
BICD1,MAPT |
| 4.434e-02 | -3.12 | extrinsic component of vacuolar membrane | cellular component | GO:0000306 | 3 | 2 | 17570 | 2233 |
WDFY3,RAB7A |
| 4.434e-02 | -3.12 | laminin-11 complex | cellular component | GO:0043260 | 3 | 2 | 17570 | 2233 |
LAMC1,LAMA5 |
| 4.436e-02 | -3.12 | purine ribonucleoside triphosphate metabolic process | biological process | GO:0009205 | 175 | 31 | 16441 | 2138 |
PFKFB4,BDNF,NDUFA5,AK2,ATP6V1A,ITPA,NDUFB5,LDHA,OLA1,ATP6V0A1,CHCHD10,COX10,HSPA1A,NDUFS7,HSPA1B,ATP5D,STOML2,SNCA,NDUFB3,AMPD3,NDUFV1,ENTPD5,NME7,ATP5G2,COQ9,HK2,SURF1,MYH3,NDUFS5,NDUFA6,FXN |
| 4.436e-02 | -3.12 | positive regulation of protein ubiquitination | biological process | GO:0031398 | 175 | 31 | 16441 | 2138 |
ARRDC3,HSPA5,SMAD7,RCHY1,PSMA1,SUMO3,PTK2,DCUN1D5,CAV1,BRCA1,ARRDC4,BIRC2,PSMF1,UBC,KDM1A,UBE2E1,RNF40,FKBP1A,TRIB3,ANAPC1,CDC16,UBE3A,CDK9,DNAJA3,ANAPC11,ANAPC10,RNF111,CTR9,CLU,BMI1,ANAPC4 |
| 4.439e-02 | -3.11 | Filamin | pfam domains | PF00630 | 11 | 4 | 16629 | 2165 |
FLNC,MYCBP2,FLNB,KDELC1 |
| 4.439e-02 | -3.11 | WH1 | pfam domains | PF00568 | 11 | 4 | 16629 | 2165 |
ENAH,SPRED2,EVL,HOMER2 |
| 4.439e-02 | -3.11 | R3H | pfam domains | PF01424 | 11 | 4 | 16629 | 2165 |
R3HDM1,NFX1,R3HDM2,PARN |
| 4.443e-02 | -3.11 | V$CEBPB_02 | MSigDB lists | V$CEBPB_02 | 245 | 41 | 17758 | 2279 |
SEPHS2,CYP24A1,TCF12,LUZP1,DDR2,H2AFJ,SLC25A12,SBF2,TMEM104,IP6K2,FOXP1,SYNJ1,MBNL1,ARID1B,PCDH7,NEK6,SLC7A11,CACNB2,CHD2,TOP1,SOBP,BDNF,MPP6,TXLNG,PPARG,SMARCAD1,EIF4A2,ARRDC3,PTPN12,ONECUT2,PDE3B,DENND4A,C1orf122,BAZ1A,SYNCRIP,KPNA3,HNRNPR,PER1,VCAN,STX18,CSMD3 |
| 4.444e-02 | -3.11 | MCM7 (minichromosome maintenance complex component 7) | protein interactions | 4176 | 149 | 29 | 16036 | 2270 |
RANBP6,MCM6,CUL7,MCM10,FN1,GINS3,TRIM16,DBF4,MCM2,POLR2A,RPA1,CAD,UBE3A,NEK6,HIF1A,CEP290,MCM5,MYC,COPS5,ORC5,TIMELESS,ATRIP,RNF2,CCDC88C,MIPOL1,TOMM34,PNMA1,TERF2,SF3A1 |
| 4.446e-02 | -3.11 | PTBP1 (polypyrimidine tract binding protein 1) | protein interactions | 5725 | 125 | 25 | 16036 | 2270 |
HMGA2,SLC3A2,CUL7,FN1,RBFOX2,SMARCAD1,HSPA5,HSD17B10,TMEM177,RANGAP1,ABCF1,HNRNPA3,UBC,ISG15,RPA1,STOML2,EPRS,COPS5,RNF2,FUS,YBX3,BMI1,ZMYM2,SRPK2,SPTAN1 |
| 4.448e-02 | -3.11 | NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | 633 | 96 | 17758 | 2279 |
ZNF254,CUL4A,ID1,BIRC6,NF1,RBFOX2,SIRT2,BCOR,HSPA1A,CIAPIN1,PAIP2,TERF2IP,BRE,ASNS,SOCS1,JAZF1,PDS5B,ZEB1,ZNF148,PEG10,VCL,AVEN,CDK6,ZBTB17,KAT8,NR6A1,LIMA1,CUX1,POU2F1,ATXN1,MCL1,HDAC8,BRCA1,SON,ERC1,SNCA,WARS,DCBLD2,SMAD3,VDR,DDAH2,SUPT4H1,BRCA2,DNAJC1,PER1,KLF4,TNFRSF10D,BAG1,BRAF,FOXO1,ZHX3,KHDRBS1,NFX1,ID2,RTN4,ATF7IP,AKT1S1,RSF1,IP6K2,TGFB2,NOL3,OPA1,SNW1,MYC,VPS72,TRIAP1,TIMELESS,ANXA5,NRIP1,TERF2,PEA15,ZNF675,PPP1R9B,KDM5B,FOXN3,ARID5B,TBRG4,PRDM1,SUPT5H,GPNMB,MEN1,FOXC1,ANGPTL4,HSPA1B,ANXA1,MFN2,NSD1,GADD45A,FGFBP1,SET,TBX3,CUL2,BMP4,RBPJ,ZAK,KAT6A |
| 4.449e-02 | -3.11 | ATF4 activates genes | REACTOME pathways | R-HSA-380994 | 25 | 7 | 8202 | 1117 |
EXOSC2,EXOSC4,ASNS,ATF4,PARN,HERPUD1,DDIT3 |
| 4.451e-02 | -3.11 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | 184 | 32 | 17758 | 2279 |
ZNF76,FEZ2,BCOR,MLH1,PRKCA,SEC16A,UBR5,SFI1,LPIN1,PRKCE,TTLL11,ZNF827,ELL,SIPA1L3,ZSWIM7,DHX33,PPCDC,CLCN6,CPNE7,MAP3K14,FBXW4,RREB1,CRIM1,PLEKHM3,METTL22,DDX60,GUF1,SLC26A11,BTBD11,RERE,SGSM2,MDN1 |
| 4.451e-02 | -3.11 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 184 | 32 | 17758 | 2279 |
ZNF706,SCAMP3,WDR13,TRIO,TMEM109,CENPB,DPM3,SSR4,IQGAP2,ATXN7L1,SUB1,DECR1,ABCA5,PCK2,CTC1,RPS6KB2,LAMC1,RAP1GAP2,GNG7,C11orf80,WBSCR22,RNH1,RAP1GDS1,VIM,SERP1,CTIF,YIF1A,RETSAT,EPRS,FTSJ1,SIL1,EIF2B3 |
| 4.451e-02 | -3.11 | GSE14308_TH17_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE14308_TH17_VS_NAIVE_CD4_TCELL_DN | 184 | 32 | 17758 | 2279 |
ESCO1,ADAMTS6,CCNL2,RPAIN,GIGYF2,MFHAS1,ABCA7,CAD,CHD7,ERI1,ATG3,TRIAP1,FAM120B,FMNL3,DEAF1,ATF4,EVL,TFCP2,PARP2,PTPN12,POLR2A,VAC14,C1orf174,FBXL5,DYNC1H1,POLE2,ZZEF1,TBXA2R,XPO6,ZNF598,PDSS2,ZNF507 |
| 4.451e-02 | -3.11 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | 184 | 32 | 17758 | 2279 |
SLC12A7,BCKDK,PGPEP1,SMARCA4,PLA2G12A,APRT,POP5,PHC2,TBC1D22A,NUP133,AP1M1,TTC3,FBXO31,LYRM5,MPST,TRIM14,TMLHE,DDX41,AP4B1,MINA,NFIA,MEF2D,SPOP,RPA1,EPRS,KDM4B,SMARCC1,YIPF2,HSPBAP1,H2AFX,DTD1,ECHDC1 |
| 4.451e-02 | -3.11 | GSE2706_2H_VS_8H_LPS_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_LPS_STIM_DC_UP | 184 | 32 | 17758 | 2279 |
SLC12A7,AK2,MIF4GD,EGR1,PAX2,PIP4K2A,JAG1,HVCN1,ZSWIM7,ANO8,PTGS1,PRADC1,ERI3,VCL,KLRD1,MSI2,FADS1,ERICH1,GNG7,EFHC1,TPRA1,ARL5B,MAT2A,ZC3H12A,DCXR,PEMT,BCAS3,CCDC85B,PTPN4,DNAJC12,C7orf50,ADK |
| 4.451e-02 | -3.11 | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | 184 | 32 | 17758 | 2279 |
VIPR1,MPI,LYRM4,WDR74,RPS29,RSL1D1,LPCAT3,PRKCA,PABPC4,SMARCB1,CAD,THAP4,MYC,ANP32B,PABPC1,ADARB1,MPP6,OSBP2,MINA,SCMH1,VIM,IMPDH2,ODC1,EIF3H,DPP4,FKBP5,TNFRSF10D,CCNB1IP1,ADK,SRP14,IPO4,SLC16A10 |
| 4.451e-02 | -3.11 | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 184 | 32 | 17758 | 2279 |
SUCLG1,PPARGC1B,PDK4,TMEM109,LETMD1,CSNK2A1,PRKCE,SH2B3,UBE3A,MLX,JAG1,PTRF,RASSF3,KDM5C,AHCYL1,TMEM14C,PPA1,PRKACB,SEH1L,LAMA4,PDK1,CUX1,ATP6V0A1,ECH1,PYCR1,ATP5D,ETFDH,FSCN1,HIPK2,BPNT1,GPAM,PTPN14 |
| 4.451e-02 | -3.11 | organelle outer membrane | cellular component | GO:0031968 | 179 | 31 | 17570 | 2233 |
ACSL5,GDAP1,SIGMAR1,TMEM109,LETMD1,MCL1,OPA1,RHOT2,CYB5B,CPT1A,LPIN1,MGST1,AMBRA1,MFN2,MIEF1,SNCA,DDX3X,RETSAT,PI4KB,PMAIP1,ATP5G2,HK2,RMDN3,FIS1,RPS6KB1,GPAM,PGAM5,DHCR7,TOMM34,NAV3,CPT1C |
| 4.455e-02 | -3.11 | CEP76 (centrosomal protein 76kDa) | protein interactions | 79959 | 143 | 28 | 16036 | 2270 |
BANP,KIAA1143,SUPT6H,WDFY3,HSPA5,CSNK2A1,PLCB1,ZMAT2,RADIL,CUTC,HSPA1A,GIGYF2,POM121,MRPS11,CAMK2D,RPS16,EP400NL,CEP290,PPFIBP1,MRPS27,ZNF85,KLHDC4,YBX3,UQCC2,AMOT,ZBTB24,PRPF19,SPTAN1 |
| 4.455e-02 | -3.11 | kinase activity | molecular function | GO:0016301 | 775 | 118 | 16491 | 2164 |
MVK,MAP2K5,PRKAB2,PDK4,TRPM6,DDR2,RIPK1,CSNK2A1,STK33,PRKCA,MAP2K3,RIOK2,CAD,ABL2,PRKD3,SHC1,NEK6,PHKA1,FGGY,RPS6KL1,IKBKB,ADCK4,CMPK1,PXK,MET,CDK6,CDK12,PRKACB,SRPK2,TNK2,PDK1,PI4KAP2,CDK4,COL4A3BP,DLG4,KSR2,GALK2,AKAP13,KCNH3,KCNH2,SGK2,STK10,FGFR1,TPK1,DYRK1B,CAMK2D,TRRAP,HIPK2,HSPB8,RPS6KB1,RIOK1,NRP1,SMG1,SEPHS2,HMGA2,XYLB,TNIK,BCKDK,TTN,MINK1,BRAF,AK2,CLK1,MAP3K13,TAF1,CAMK1,SLK,AK6,TRIO,PIK3R4,TKFC,IP6K2,TGFB2,CSNK1A1,RPS6KA5,TGFBR2,PIP4K2A,PRKCH,ABL1,PRKCE,NPRL2,PI4KB,GTF2H1,MAP3K14,ALDH18A1,MAP3K12,PRPS1,N4BP2,CLK2,RPS6KB2,PFKFB4,GTF2H3,SIK3,CAMKK2,CRIM1,TEX14,TBRG4,OBSCN,PTK2,PPIP5K2,PEAK1,PIK3CB,OXSR1,TRIB3,NME7,CDK9,IRAK2,RIOK3,HK2,ATM,CASS4,TBCK,ADK,BRSK2,RPS6KC1,ZAK,MAP2K4,STK4 |
| 4.456e-02 | -3.11 | USP15 (ubiquitin specific peptidase 15) | protein interactions | 9958 | 131 | 26 | 16036 | 2270 |
USP7,CCDC57,RBCK1,FN1,PRPF31,SMAD7,USP10,ADSL,STK33,STAM,BIRC2,UBC,ZC3H13,SMAD3,RNF40,SHC1,COPS5,MAD1L1,USP20,JOSD1,SENP3,PRPF4,USP11,ZMYM2,TERF2,USP15 |
| 4.461e-02 | -3.11 | BIOCARTA_MAPK_PATHWAY | MSigDB lists | BIOCARTA_MAPK_PATHWAY | 86 | 17 | 17758 | 2279 |
MAP2K5,BRAF,MAP3K13,RIPK1,MEF2D,TGFB2,RPS6KA5,MAP2K3,SHC1,MYC,IKBKB,RPS6KB1,MAP3K14,MAP3K12,MAP2K4,RPS6KB2,MEF2C |
| 4.465e-02 | -3.11 | glycerophospholipid biosynthetic process | biological process | GO:0046474 | 195 | 34 | 16441 | 2138 |
PIGM,PIGN,LPCAT2,GPAT3,PIGH,PIK3R4,PLA2G12A,DPM3,LPCAT3,LCLAT1,SYNJ1,PIP4K2A,LPIN1,PI4KB,LPIN2,PIGG,SYNJ2,CPNE7,PNPLA3,MGLL,LPCAT1,FGF2,AGPAT4,GPCPD1,PITPNB,PIK3CB,VAC14,TAMM41,ALG5,PEMT,ABHD3,ATM,GPAM,MTMR1 |
| 4.466e-02 | -3.11 | LEE_LIVER_CANCER_SURVIVAL_DN | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_DN | 164 | 29 | 17758 | 2279 |
NAA38,MCM6,RWDD1,KHDRBS1,CDK4,ACTR3,PBX1,MCM2,PDCD5,ODC1,BZW2,PHLDA2,MFSD10,HDDC2,NOP56,DCTPP1,MTHFD2,ARHGAP18,NSF,HIF1A,DSG2,SET,NCBP2,RAN,SERPINH1,FBL,VCL,ZNF532,HN1 |
| 4.466e-02 | -3.11 | V$EVI1_05 | MSigDB lists | V$EVI1_05 | 164 | 29 | 17758 | 2279 |
MAP2K5,NRAS,NF1,UBXN1,SATB2,UBE2K,ENOX1,MBNL2,ONECUT2,MBNL1,NCDN,STOML2,RTN1,MSX2,SRSF2,SUFU,NEK6,DNAJC1,JAZF1,LUC7L3,HOXA3,RRAGA,CSMD3,CHD2,NRP1,FUT11,MGLL,MID1,SRPK2 |
| 4.468e-02 | -3.11 | protein binding, bridging | molecular function | GO:0030674 | 154 | 28 | 16491 | 2164 |
SH2D3A,CRADD,SKAP2,ANK2,KHDRBS1,CUX1,WWC1,HSH2D,CAV1,EVPL,TRIM22,MEN1,DSP,CSTA,STAM,PAG1,ANXA1,IRS1,VPS18,CHN1,BICD1,SHC1,STX1A,FSCN1,ARHGAP1,AP2S1,NMD3,CAV2 |
| 4.471e-02 | -3.11 | RCC1 (regulator of chromosome condensation 1) | protein interactions | 1104 | 84 | 18 | 16036 | 2270 |
CUL7,FN1,RANGAP1,CSNK1A1,RPA1,FLAD1,DDAH2,RANBP2,NAV1,KPNA3,LUC7L3,GLYR1,TRMT2A,WIZ,SHMT2,RNF2,RAN,HNRNPM |
| 4.473e-02 | -3.11 | acute_leukaemic_transformation_of_primary_myelofibrosis | COSMIC cancer mutations | acute_leukaemic_transformation_of_primary_myelofibrosis | 32 | 8 | 17775 | 2278 |
SH2B3,SRSF2,NRAS,NF1,CUX1,RUNX1,PHF6,FGFR1 |
| 4.473e-02 | -3.11 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_primary_myelofibrosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_primary_myelofibrosis | 32 | 8 | 17775 | 2278 |
SH2B3,SRSF2,NRAS,NF1,CUX1,RUNX1,PHF6,FGFR1 |
| 4.473e-02 | -3.11 | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | MSigDB lists | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | 118 | 22 | 17758 | 2279 |
EFNB2,PSAT1,TRIM16,ZNF512B,ID2,GPNMB,PHGDH,DDIT4,DCBLD2,IGF2BP3,DKK1,TRIB3,JAG1,ASNS,SACS,INSIG1,SLC7A11,VCAN,STC2,CAV2,TMEM158,DDIT3 |
| 4.473e-02 | -3.11 | NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN | MSigDB lists | NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN | 118 | 22 | 17758 | 2279 |
ARHGAP26,AOC3,SLC40A1,RPS29,FERMT2,C5AR1,ZFP36L1,VARS,SBDS,DENR,UBTF,CAT,RPS16,EHMT2,SREBF2,SET,CFD,MMP14,SELT,AHCYL1,SH3PXD2A,AP2S1 |
| 4.476e-02 | -3.11 | non_seminoma | COSMIC cancer mutations | non_seminoma | 505 | 78 | 17775 | 2278 |
NF1,PDK4,DDR2,TRPM6,MKS1,CSNK2A1,RIPK1,STK33,PRKCA,UBR5,MAP2K3,RIOK2,ABL2,PRKD3,NEK6,RPS6KL1,IKBKB,ADCK4,MET,CDK6,CDK12,PRKACB,SRPK2,TNK2,NRAS,BRD4,PDK1,CDK4,ALDH1L2,NOL8,TFPI,KSR2,SGK2,STK10,FGFR1,DYRK1B,CAMK2D,TRRAP,HIPK2,RPS6KB1,RIOK1,MDN1,PDCD11,SMG1,BCKDK,TNIK,BRAF,SEC24D,MAP3K13,SUPT6H,CLK1,TAF1,CAMK1,TRIO,PIK3R4,TGFBR2,CSNK1A1,PRKCE,PRKCH,ABL1,MAP3K12,RPS6KB2,CLK2,SIK3,CAMKK2,TEX14,OBSCN,OXSR1,TRIB3,KIDINS220,TMEM237,RIOK3,ATM,TBCK,RPS6KC1,MAP2K4,ZAK,STK4 |
| 4.481e-02 | -3.11 | MICROTUBULE_BASED_MOVEMENT | MSigDB lists | MICROTUBULE_BASED_MOVEMENT | 16 | 5 | 17758 | 2279 |
MAP1S,OPA1,RHOT2,KIF1B,KIF5A |
| 4.481e-02 | -3.11 | PID_DNA_PK_PATHWAY | MSigDB lists | PID_DNA_PK_PATHWAY | 16 | 5 | 17758 | 2279 |
LIG4,CSNK2A1,APTX,XRCC4,APLF |
| 4.481e-02 | -3.11 | HISTONE_ACETYLTRANSFERASE_ACTIVITY | MSigDB lists | HISTONE_ACETYLTRANSFERASE_ACTIVITY | 16 | 5 | 17758 | 2279 |
KAT8,SRCAP,BRCA2,TAF1,KAT6A |
| 4.481e-02 | -3.11 | GALE_APL_WITH_FLT3_MUTATED_DN | MSigDB lists | GALE_APL_WITH_FLT3_MUTATED_DN | 16 | 5 | 17758 | 2279 |
RABAC1,NDUFV1,OASL,ST3GAL5,PQBP1 |
| 4.481e-02 | -3.11 | REACTOME_RAP1_SIGNALLING | MSigDB lists | REACTOME_RAP1_SIGNALLING | 16 | 5 | 17758 | 2279 |
RAP1A,PRKACB,RAPGEF4,RAP1GAP2,RAP1B |
| 4.491e-02 | -3.10 | ATP metabolic process | biological process | GO:0046034 | 162 | 29 | 16441 | 2138 |
PFKFB4,BDNF,NDUFA5,AK2,ATP6V1A,NDUFB5,LDHA,OLA1,ATP6V0A1,CHCHD10,COX10,HSPA1A,NDUFS7,HSPA1B,ATP5D,STOML2,SNCA,NDUFB3,AMPD3,NDUFV1,ENTPD5,ATP5G2,COQ9,HK2,SURF1,MYH3,NDUFS5,NDUFA6,FXN |
| 4.493e-02 | -3.10 | Endogenous_retrovirus_rcpt | interpro domains | IPR009357 | 3 | 2 | 18293 | 2341 |
SLC52A2,SLC52A3 |
| 4.493e-02 | -3.10 | Arp3_met | interpro domains | IPR015623 | 3 | 2 | 18293 | 2341 |
ACTR3B,ACTR3 |
| 4.493e-02 | -3.10 | DNA_mismatch_repair_fam | interpro domains | IPR002099 | 3 | 2 | 18293 | 2341 |
PMS1,MLH1 |
| 4.493e-02 | -3.10 | Angiomotin | interpro domains | IPR009114 | 3 | 2 | 18293 | 2341 |
AMOTL1,AMOT |
| 4.493e-02 | -3.10 | TatD_family | interpro domains | IPR001130 | 3 | 2 | 18293 | 2341 |
TATDN1,TATDN3 |
| 4.493e-02 | -3.10 | ACE1_Sec16_Sec31 | interpro domains | IPR024298 | 3 | 2 | 18293 | 2341 |
SEC31A,SEC16A |
| 4.493e-02 | -3.10 | S-Ado-L-homoCys_hydrolase_CS | interpro domains | IPR020082 | 3 | 2 | 18293 | 2341 |
AHCYL1,AHCYL2 |
| 4.493e-02 | -3.10 | Caveolin_CS | interpro domains | IPR018361 | 3 | 2 | 18293 | 2341 |
CAV1,CAV2 |
| 4.493e-02 | -3.10 | CPH_domain | interpro domains | IPR021097 | 3 | 2 | 18293 | 2341 |
HERC2,CUL7 |
| 4.493e-02 | -3.10 | PLipase/COase/thioEstase | interpro domains | IPR003140 | 3 | 2 | 18293 | 2341 |
LYPLAL1,LYPLA2 |
| 4.493e-02 | -3.10 | RNA_pol_bsu_CS | interpro domains | IPR007121 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | Cu_amine_oxidase_N2 | interpro domains | IPR015800 | 3 | 2 | 18293 | 2341 |
AOC3,AOC2 |
| 4.493e-02 | -3.10 | VPS13 | interpro domains | IPR026847 | 3 | 2 | 18293 | 2341 |
VPS13D,VPS13C |
| 4.493e-02 | -3.10 | FGF1-bd | interpro domains | IPR010510 | 3 | 2 | 18293 | 2341 |
FGFBP1,FGFBP3 |
| 4.493e-02 | -3.10 | Rubredoxin-type_fold | interpro domains | IPR004039 | 3 | 2 | 18293 | 2341 |
RCHY1,MCM6 |
| 4.493e-02 | -3.10 | Lipin_mid | interpro domains | IPR031703 | 3 | 2 | 18293 | 2341 |
LPIN2,LPIN1 |
| 4.493e-02 | -3.10 | Methyltransf_12 | interpro domains | IPR013217 | 3 | 2 | 18293 | 2341 |
METTL6,METTL8 |
| 4.493e-02 | -3.10 | GART_AS | interpro domains | IPR001555 | 3 | 2 | 18293 | 2341 |
GART,ALDH1L2 |
| 4.493e-02 | -3.10 | GCFC_dom | interpro domains | IPR022783 | 3 | 2 | 18293 | 2341 |
PAXBP1,TFIP11 |
| 4.493e-02 | -3.10 | Cu_amine_oxidase | interpro domains | IPR000269 | 3 | 2 | 18293 | 2341 |
AOC3,AOC2 |
| 4.493e-02 | -3.10 | Ado_hCys_hydrolase_NAD-bd | interpro domains | IPR015878 | 3 | 2 | 18293 | 2341 |
AHCYL1,AHCYL2 |
| 4.493e-02 | -3.10 | TBD | interpro domains | IPR024581 | 3 | 2 | 18293 | 2341 |
TBKBP1,TANK |
| 4.493e-02 | -3.10 | RMMBL | interpro domains | IPR011108 | 3 | 2 | 18293 | 2341 |
CPSF3,CPSF3L |
| 4.493e-02 | -3.10 | AP_complex_bsu_1_2_4 | interpro domains | IPR016342 | 3 | 2 | 18293 | 2341 |
AP1B1,AP4B1 |
| 4.493e-02 | -3.10 | Cu_amine_oxidase_N-reg | interpro domains | IPR016182 | 3 | 2 | 18293 | 2341 |
AOC3,AOC2 |
| 4.493e-02 | -3.10 | CPT_N | interpro domains | IPR032476 | 3 | 2 | 18293 | 2341 |
CPT1A,CPT1C |
| 4.493e-02 | -3.10 | RFX1_trans_act | interpro domains | IPR007668 | 3 | 2 | 18293 | 2341 |
RFX1,RFX2 |
| 4.493e-02 | -3.10 | GHMP_knse_ATP-bd_CS | interpro domains | IPR006203 | 3 | 2 | 18293 | 2341 |
MVK,GALK2 |
| 4.493e-02 | -3.10 | MT_TRM10-typ | interpro domains | IPR028564 | 3 | 2 | 18293 | 2341 |
TRMT10B,TRMT10A |
| 4.493e-02 | -3.10 | 6PGDH_NADP-bd | interpro domains | IPR006115 | 3 | 2 | 18293 | 2341 |
GLYR1,PGD |
| 4.493e-02 | -3.10 | P5CR_dimer | interpro domains | IPR029036 | 3 | 2 | 18293 | 2341 |
PYCRL,PYCR1 |
| 4.493e-02 | -3.10 | AT_hook-like | interpro domains | IPR020478 | 3 | 2 | 18293 | 2341 |
HMGA2,SRCAP |
| 4.493e-02 | -3.10 | AKAP95 | interpro domains | IPR007071 | 3 | 2 | 18293 | 2341 |
AKAP8L,ZNF326 |
| 4.493e-02 | -3.10 | ITPRIP_fam | interpro domains | IPR026250 | 3 | 2 | 18293 | 2341 |
ITPRIPL1,ITPRIP |
| 4.493e-02 | -3.10 | rRNA-MeTfrase_E | interpro domains | IPR015507 | 3 | 2 | 18293 | 2341 |
FTSJ3,FTSJ1 |
| 4.493e-02 | -3.10 | VPS13_mid_rpt | interpro domains | IPR031642 | 3 | 2 | 18293 | 2341 |
VPS13D,VPS13C |
| 4.493e-02 | -3.10 | DUF1087 | interpro domains | IPR009463 | 3 | 2 | 18293 | 2341 |
CHD3,CHD5 |
| 4.493e-02 | -3.10 | Caveolin | interpro domains | IPR001612 | 3 | 2 | 18293 | 2341 |
CAV1,CAV2 |
| 4.493e-02 | -3.10 | Cu_amine_oxidase_N3 | interpro domains | IPR015802 | 3 | 2 | 18293 | 2341 |
AOC3,AOC2 |
| 4.493e-02 | -3.10 | Adenosylhomocysteinase | interpro domains | IPR000043 | 3 | 2 | 18293 | 2341 |
AHCYL1,AHCYL2 |
| 4.493e-02 | -3.10 | VPS13_N2 | interpro domains | IPR031646 | 3 | 2 | 18293 | 2341 |
VPS13D,VPS13C |
| 4.493e-02 | -3.10 | Requiem/DPF_N_dom | interpro domains | IPR025750 | 3 | 2 | 18293 | 2341 |
DPF3,DPF2 |
| 4.493e-02 | -3.10 | Uncharacterised_DM10 | interpro domains | IPR006602 | 3 | 2 | 18293 | 2341 |
EFHC1,NME7 |
| 4.493e-02 | -3.10 | FAM122 | interpro domains | IPR026716 | 3 | 2 | 18293 | 2341 |
FAM122B,FAM122C |
| 4.493e-02 | -3.10 | RNA_pol_Rpb2_7 | interpro domains | IPR007641 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | CHD_N | interpro domains | IPR012958 | 3 | 2 | 18293 | 2341 |
CHD3,CHD5 |
| 4.493e-02 | -3.10 | Tex_RuvX-like_dom | interpro domains | IPR023097 | 3 | 2 | 18293 | 2341 |
SRBD1,SUPT6H |
| 4.493e-02 | -3.10 | Beta-propeller_rpt_TECPR | interpro domains | IPR006624 | 3 | 2 | 18293 | 2341 |
HERC2,TECPR2 |
| 4.493e-02 | -3.10 | DALR_anticod-bd | interpro domains | IPR008909 | 3 | 2 | 18293 | 2341 |
RARS,RARS2 |
| 4.493e-02 | -3.10 | Ala-tRNA-synth_IIc_core | interpro domains | IPR018165 | 3 | 2 | 18293 | 2341 |
AARS,AARS2 |
| 4.493e-02 | -3.10 | Lipin_N | interpro domains | IPR007651 | 3 | 2 | 18293 | 2341 |
LPIN2,LPIN1 |
| 4.493e-02 | -3.10 | tRNA_MeTrfase_TRMD/TRM10 | interpro domains | IPR016009 | 3 | 2 | 18293 | 2341 |
TRMT10B,TRMT10A |
| 4.493e-02 | -3.10 | FOXO-TAD | interpro domains | IPR032067 | 3 | 2 | 18293 | 2341 |
FOXO1,FOXO3 |
| 4.493e-02 | -3.10 | VASP_tetra | interpro domains | IPR014885 | 3 | 2 | 18293 | 2341 |
ENAH,EVL |
| 4.493e-02 | -3.10 | FDF_dom | interpro domains | IPR019050 | 3 | 2 | 18293 | 2341 |
LSM14A,EDC3 |
| 4.493e-02 | -3.10 | LNS2 | interpro domains | IPR013209 | 3 | 2 | 18293 | 2341 |
LPIN2,LPIN1 |
| 4.493e-02 | -3.10 | CDC48_domain_2-like | interpro domains | IPR029067 | 3 | 2 | 18293 | 2341 |
NSF,PEX1 |
| 4.493e-02 | -3.10 | RNA_pol_bsu_protrusion | interpro domains | IPR007644 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | DUF1086 | interpro domains | IPR009462 | 3 | 2 | 18293 | 2341 |
CHD3,CHD5 |
| 4.493e-02 | -3.10 | Angiomotin_C | interpro domains | IPR024646 | 3 | 2 | 18293 | 2341 |
AMOTL1,AMOT |
| 4.493e-02 | -3.10 | DNA-dir_RNA_pol_su2 | interpro domains | IPR015712 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | Lsm14_N | interpro domains | IPR025609 | 3 | 2 | 18293 | 2341 |
LSM14A,EDC3 |
| 4.493e-02 | -3.10 | RNA_pol_Rpb2_3 | interpro domains | IPR007645 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | HTH_base_excis_C | interpro domains | IPR023170 | 3 | 2 | 18293 | 2341 |
OGG1,MUTYH |
| 4.493e-02 | -3.10 | tRNA_m1G_MeTrfase_euk | interpro domains | IPR007356 | 3 | 2 | 18293 | 2341 |
TRMT10B,TRMT10A |
| 4.493e-02 | -3.10 | HhH-GPD_domain | interpro domains | IPR003265 | 3 | 2 | 18293 | 2341 |
OGG1,MUTYH |
| 4.493e-02 | -3.10 | DFDF | interpro domains | IPR025762 | 3 | 2 | 18293 | 2341 |
LSM14A,EDC3 |
| 4.493e-02 | -3.10 | NHS_fam | interpro domains | IPR024845 | 3 | 2 | 18293 | 2341 |
NHSL1,NHS |
| 4.493e-02 | -3.10 | TOM1 | interpro domains | IPR014645 | 3 | 2 | 18293 | 2341 |
TOM1L2,TOM1L1 |
| 4.493e-02 | -3.10 | CHD_C2 | interpro domains | IPR012957 | 3 | 2 | 18293 | 2341 |
CHD3,CHD5 |
| 4.493e-02 | -3.10 | RNA_pol_Rpb2_2 | interpro domains | IPR007642 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | RNA_pol_RPB2_OB-fold | interpro domains | IPR014724 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | B-adaptin_app_sub_C | interpro domains | IPR015151 | 3 | 2 | 18293 | 2341 |
AP1B1,AP4B1 |
| 4.493e-02 | -3.10 | DNA-dir_RNA_pol_su2_6 | interpro domains | IPR007120 | 3 | 2 | 18293 | 2341 |
POLR3B,POLR1B |
| 4.493e-02 | -3.10 | MGS-like_dom | interpro domains | IPR011607 | 3 | 2 | 18293 | 2341 |
CAD,ATIC |
| 4.493e-02 | -3.10 | CCAAT-binding_factor | interpro domains | IPR005612 | 3 | 2 | 18293 | 2341 |
NOC3L,CEBPZ |
| 4.493e-02 | -3.10 | Uncharacterised_SERF | interpro domains | IPR007513 | 3 | 2 | 18293 | 2341 |
ZNF706,SERF2 |
| 4.493e-02 | -3.10 | Ala-tRNA-synth_IIc_N | interpro domains | IPR018164 | 3 | 2 | 18293 | 2341 |
AARS,AARS2 |
| 4.493e-02 | -3.10 | Cu_amine_oxidase_C | interpro domains | IPR015798 | 3 | 2 | 18293 | 2341 |
AOC3,AOC2 |
| 4.505e-02 | -3.10 | ABE_VEGFA_TARGETS_2HR | MSigDB lists | ABE_VEGFA_TARGETS_2HR | 32 | 8 | 17758 | 2279 |
CARS,ZCCHC14,UPP1,CUX1,RCAN1,MCM2,XPO7,HERPUD1 |
| 4.505e-02 | -3.10 | FARDIN_HYPOXIA_11 | MSigDB lists | FARDIN_HYPOXIA_11 | 32 | 8 | 17758 | 2279 |
PFKFB4,PDK1,PLOD1,BHLHE40,FUT11,ANGPTL4,MAPT,DDIT4 |
| 4.505e-02 | -3.10 | KASLER_HDAC7_TARGETS_2_DN | MSigDB lists | KASLER_HDAC7_TARGETS_2_DN | 32 | 8 | 17758 | 2279 |
KLHL24,SESN2,CUL7,STC2,IFITM2,BHLHE40,SEMA6A,PYCR1 |
| 4.505e-02 | -3.10 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | MSigDB lists | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | 32 | 8 | 17758 | 2279 |
RANBP2,KPNA1,NUP133,BANF1,NUP43,NUP214,SEH1L,POM121 |
| 4.505e-02 | -3.10 | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | MSigDB lists | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | 32 | 8 | 17758 | 2279 |
RANBP2,NUP133,NCBP2,NUP43,CPSF3,NUP214,POM121,SEH1L |
| 4.505e-02 | -3.10 | skin-upper_leg-benign_melanocytic_nevus-compound | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-compound | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | ER-HER-positive_carcinoma | COSMIC cancer mutations | ER-HER-positive_carcinoma | 3 | 2 | 17775 | 2278 |
ARID1A,GPBP1L1 |
| 4.505e-02 | -3.10 | skin-face-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-face-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-leg-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-leg-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-flank-benign_melanocytic_nevus-junctional | COSMIC cancer mutations | skin-flank-benign_melanocytic_nevus-junctional | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-arm-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-arm-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | kidney-other-adenoma | COSMIC cancer mutations | kidney-other-adenoma | 3 | 2 | 17775 | 2278 |
BRAF,MET |
| 4.505e-02 | -3.10 | skin-upper_back-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-upper_back-malignant_melanoma-superficial_spreading | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-upper_back-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-upper_back-malignant_melanoma-lentigo_maligna | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-shoulder-benign_melanocytic_nevus-melanocytic_tumour | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-melanocytic_tumour | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-abdomen-benign_melanocytic_nevus-intradermal | COSMIC cancer mutations | skin-abdomen-benign_melanocytic_nevus-intradermal | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-neck-benign_melanocytic_nevus-intradermal | COSMIC cancer mutations | skin-neck-benign_melanocytic_nevus-intradermal | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-acral-malignant_melanoma-nodular | COSMIC cancer mutations | skin-acral-malignant_melanoma-nodular | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-back-benign_melanocytic_nevus-compound | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-compound | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-ankle-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-ankle-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-intermittently_sun_exposed_site-malignant_melanoma | COSMIC cancer mutations | skin-intermittently_sun_exposed_site-malignant_melanoma | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | central_nervous_system-occipital_lobe-other-ganglioglioma-dysembryoplastic_neuroepithelial_tumour | COSMIC cancer mutations | central_nervous_system-occipital_lobe-other-ganglioglioma-dysembryoplastic_neuroepithelial_tumour | 3 | 2 | 17775 | 2278 |
BRAF,KIAA1549 |
| 4.505e-02 | -3.10 | skin-face-benign_melanocytic_nevus-intradermal | COSMIC cancer mutations | skin-face-benign_melanocytic_nevus-intradermal | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-forearm-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-forearm-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | haematopoietic_and_lymphoid_tissue-other-Rosai-Dorfman_disease | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-Rosai-Dorfman_disease | 3 | 2 | 17775 | 2278 |
BRAF,MET |
| 4.505e-02 | -3.10 | central_nervous_system-frontal_lobe-other-papillary_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-frontal_lobe-other-papillary_glioneuronal_tumour | 3 | 2 | 17775 | 2278 |
BRAF,FGFR1 |
| 4.505e-02 | -3.10 | bone-mandible-cemento-ossifying_fibroma | COSMIC cancer mutations | bone-mandible-cemento-ossifying_fibroma | 3 | 2 | 17775 | 2278 |
FUS,CDC73 |
| 4.505e-02 | -3.10 | skin-face-adnexal_tumour-other | COSMIC cancer mutations | skin-face-adnexal_tumour-other | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-breast-benign_melanocytic_nevus-compound | COSMIC cancer mutations | skin-breast-benign_melanocytic_nevus-compound | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | NS-other-Krukenberg_tumour | COSMIC cancer mutations | NS-other-Krukenberg_tumour | 3 | 2 | 17775 | 2278 |
RNF43,NRAS |
| 4.505e-02 | -3.10 | skin-neck-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-neck-malignant_melanoma-lentigo_maligna | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-intermittently_sun_exposed_site-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-intermittently_sun_exposed_site-malignant_melanoma-superficial_spreading | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | cervical | COSMIC cancer mutations | cervical | 3 | 2 | 17775 | 2278 |
BRAF,KIAA1549 |
| 4.505e-02 | -3.10 | skin-arm-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-arm-malignant_melanoma-lentigo_maligna | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-neck-benign_melanocytic_nevus | COSMIC cancer mutations | skin-neck-benign_melanocytic_nevus | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-upper_arm-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-upper_arm-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-leg-benign_melanocytic_nevus-junctional | COSMIC cancer mutations | skin-leg-benign_melanocytic_nevus-junctional | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-benign_melanocytic_nevus-melanocytic_tumour | COSMIC cancer mutations | skin-benign_melanocytic_nevus-melanocytic_tumour | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-breast-benign_melanocytic_nevus-intradermal | COSMIC cancer mutations | skin-breast-benign_melanocytic_nevus-intradermal | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-other-sarcoma | COSMIC cancer mutations | skin-other-sarcoma | 3 | 2 | 17775 | 2278 |
BRAF,MLH1 |
| 4.505e-02 | -3.10 | skin-neck-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-neck-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-lower_back-benign_melanocytic_nevus | COSMIC cancer mutations | skin-lower_back-benign_melanocytic_nevus | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-upper_arm-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-upper_arm-malignant_melanoma-lentigo_maligna | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-back-benign_melanocytic_nevus-dysplastic | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-dysplastic | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-buttock-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-buttock-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-buttock-benign_melanocytic_nevus-junctional | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-junctional | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-elbow-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-elbow-malignant_melanoma-superficial_spreading | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | breast-carcinoma-ER-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-HER-positive_carcinoma | 3 | 2 | 17775 | 2278 |
ARID1A,GPBP1L1 |
| 4.505e-02 | -3.10 | skin-buttock-benign_melanocytic_nevus-intradermal | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-intradermal | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-upper_back-benign_melanocytic_nevus | COSMIC cancer mutations | skin-upper_back-benign_melanocytic_nevus | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-elbow-benign_melanocytic_nevus | COSMIC cancer mutations | skin-elbow-benign_melanocytic_nevus | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-shoulder-benign_melanocytic_nevus-compound | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-compound | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | small_intestine-duodenum-carcinoid-endocrine_tumour | COSMIC cancer mutations | small_intestine-duodenum-carcinoid-endocrine_tumour | 3 | 2 | 17775 | 2278 |
BRAF,MEN1 |
| 4.505e-02 | -3.10 | skin-upper_leg-benign_melanocytic_nevus-dysplastic | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-dysplastic | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-foot-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-foot-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-anorectal-malignant_melanoma | COSMIC cancer mutations | skin-anorectal-malignant_melanoma | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | Rosai-Dorfman_disease | COSMIC cancer mutations | Rosai-Dorfman_disease | 3 | 2 | 17775 | 2278 |
BRAF,MET |
| 4.505e-02 | -3.10 | genital_tract-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | genital_tract-germ_cell_tumour-non_seminoma | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-lower_extremity-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-lower_extremity-malignant_melanoma-superficial_spreading | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-genital-malignant_melanoma-nodular | COSMIC cancer mutations | skin-genital-malignant_melanoma-nodular | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-elbow-malignant_melanoma | COSMIC cancer mutations | skin-elbow-malignant_melanoma | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-back-benign_melanocytic_nevus-lentiginous_nevus | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-lentiginous_nevus | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-upper_extremity-malignant_melanoma-nodular | COSMIC cancer mutations | skin-upper_extremity-malignant_melanoma-nodular | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-back-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-back-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | intermittently_sun_exposed_site | COSMIC cancer mutations | intermittently_sun_exposed_site | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-lower_back-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-lower_back-malignant_melanoma-superficial_spreading | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | central_nervous_system-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-glioma-oligodendroglioma_Grade_III | 3 | 2 | 17775 | 2278 |
BRAF,KIAA1549 |
| 4.505e-02 | -3.10 | skin-head_neck-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-head_neck-malignant_melanoma-lentigo_maligna | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-hand-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-hand-benign_melanocytic_nevus-Spitz | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-elbow-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-elbow-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-back-benign_melanocytic_nevus-junctional | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-junctional | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-buttock-benign_melanocytic_nevus-dysplastic | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-dysplastic | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | gastrointestinal_tract_(site_indeterminate)-carcinoid-endocrine_tumour-gastrinoma | COSMIC cancer mutations | gastrointestinal_tract_(site_indeterminate)-carcinoid-endocrine_tumour-gastrinoma | 3 | 2 | 17775 | 2278 |
BRAF,MEN1 |
| 4.505e-02 | -3.10 | skin-upper_leg-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-upper_leg-malignant_melanoma-spitzoid | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.505e-02 | -3.10 | skin-abdomen-benign_melanocytic_nevus-compound | COSMIC cancer mutations | skin-abdomen-benign_melanocytic_nevus-compound | 3 | 2 | 17775 | 2278 |
BRAF,NRAS |
| 4.513e-02 | -3.10 | V$HOXA4_Q2 | MSigDB lists | V$HOXA4_Q2 | 259 | 43 | 17758 | 2279 |
TNNC1,COMMD10,HMGA2,CGN,SSH2,CYLD,NPAS2,ACTR3,ZFP36L1,RNF43,CORO6,POGZ,RSRC1,PHC2,TECTA,ZNF827,FSIP2,MMP14,MED24,BDNF,COL17A1,SESN2,MON1A,ZNF654,WDPCP,FRA10AC1,POU2F1,ARID1A,MBNL2,SLC9A5,NR2F1,STOML2,CAMK2D,IFT81,NSD1,SPAG9,SYNCRIP,PER1,LUC7L3,H2AFX,BMP4,NRP1,MEF2C |
| 4.516e-02 | -3.10 | TAF1 (TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa) | protein interactions | 6872 | 67 | 15 | 16036 | 2270 |
TAF2,UBTF,RANBP2,SUB1,MSX1,GTF2A1,TAF1,CCNT1,TAF3,TAF4,TBPL1,CSNK2A1,TAF12,MEN1,TAF9B |
| 4.524e-02 | -3.10 | appendage morphogenesis | biological process | GO:0035107 | 149 | 27 | 16441 | 2138 |
FGF9,MSX1,CHST11,FBXW4,PCNT,ATRX,WDPCP,RDH10,MKS1,PBX1,SOX4,FLVCR1,MBNL1,FGFR1,RPGRIP1L,SKI,DKK1,CHD7,MSX2,ZNF358,ACD,TBX3,MYH3,IFT140,SEMA3C,BMP4,DYNC2H1 |
| 4.524e-02 | -3.10 | limb morphogenesis | biological process | GO:0035108 | 149 | 27 | 16441 | 2138 |
FGF9,MSX1,CHST11,FBXW4,PCNT,ATRX,WDPCP,RDH10,MKS1,PBX1,SOX4,FLVCR1,MBNL1,FGFR1,RPGRIP1L,SKI,DKK1,CHD7,MSX2,ZNF358,ACD,TBX3,MYH3,IFT140,SEMA3C,BMP4,DYNC2H1 |
| 4.530e-02 | -3.09 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP | 191 | 33 | 17758 | 2279 |
THOC5,DBF4,OLA1,JMJD6,PDCD5,KDM1A,SHMT2,POLE3,PRMT3,NUDC,MYB,FAM98A,TIMM8B,RFC4,GINS3,EIF3J,GNL3,KIF15,TPM4,PSMG1,RAP1GDS1,MCM2,RBM28,BATF3,RAD54B,EXO1,SLC39A14,VDR,RBBP8,TRAP1,EIF2S1,PFDN2,C18orf25 |
| 4.530e-02 | -3.09 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | 191 | 33 | 17758 | 2279 |
SEPHS2,TCF12,FEZ2,ATP6V1A,TFIP11,RSF1,HLTF,NUP43,INPP1,BIRC2,LPIN1,NRF1,NUP133,SEC24C,CTR9,HARS2,YARS,CDK12,KLRD1,TIMM8B,STAMBP,PSPC1,ATG12,ARHGEF12,C1orf174,BAZ2B,KPNA3,POLE2,HIPK2,ZCCHC6,TNFRSF1A,TBL1X,MED20 |
| 4.530e-02 | -3.09 | GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN | 191 | 33 | 17758 | 2279 |
SEPHS2,MIF4GD,CCDC58,DDX19A,PRAF2,PRPF39,PIP4K2A,PHLDA2,SMARCB1,PTPN2,MPHOSPH10,COPS3,MCM5,TANK,CELF1,PRMT3,TXLNG,HSPA5,WDHD1,TBRG4,POLR3A,ISG15,TSR1,COQ9,KLF4,DNAJA3,SYNGR2,TBPL1,MSH3,FKBP5,RBM26,BPNT1,FIP1L1 |
| 4.530e-02 | -3.09 | GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_DN | 191 | 33 | 17758 | 2279 |
XYLB,USP7,ARHGAP26,SARS,AK2,OLA1,AARS,PSMF1,FKBP1A,PCOLCE2,WNT16,SLC25A23,YARS,AVEN,SEC24A,ATG9A,FOXN3,LDHA,BCS1L,RAP1GDS1,PRDM1,MBNL2,HLA-DMA,POLE2,NSMCE1,FDPS,TSSC1,PPP3CC,MBD6,NDUFS5,COPS6,TBCK,MTCH1 |
| 4.530e-02 | -3.09 | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP | 191 | 33 | 17758 | 2279 |
RTTN,FBXO45,BCKDK,ABCA3,CUL4A,TRIO,OLA1,NUP43,ZMAT2,FNIP2,HRG,C15orf41,NUDC,PCSK6,NARS2,DDHD1,FBXW4,DDX24,RNMT,LSM12,SLC35D1,GSTCD,TTC28,C1orf174,YTHDF2,RETSAT,NME7,HSPBAP1,LUC7L3,WDR7,EIF2B3,POLR1C,SGSM3 |
| 4.530e-02 | -3.09 | GSE3982_MAST_CELL_VS_TH2_DN | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_DN | 191 | 33 | 17758 | 2279 |
DDX18,RIBC2,ARFIP2,QSER1,URB1,RSRC1,PITPNM1,ETFB,DCTPP1,SACS,ARMC6,PPFIBP1,TIMELESS,ZEB1,GSTA4,RAN,COQ3,TRIP13,CTC1,HN1,PDK1,POU2F1,GNL1,ZDHHC14,CRYBG3,RPA1,FBXO21,FKBP5,BLMH,ECHDC1,MUTYH,KIF1B,P2RY11 |
| 4.530e-02 | -3.09 | GSE360_L_DONOVANI_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_DC_DN | 191 | 33 | 17758 | 2279 |
CYP24A1,ARHGAP26,MCM6,ID1,FOXO1,KIAA0232,LAGE3,ID2,EVPL,NUP160,IGF2BP3,NOP56,GART,MCM5,RABGAP1L,RAN,KIAA0922,FBL,FADS1,ANK2,MARCKSL1,SLC35D1,OASL,MTR,FOXC1,CTIF,RPA1,SLC7A1,FDPS,SQLE,DHCR7,MMP16,C18orf25 |
| 4.530e-02 | -3.09 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 191 | 33 | 17758 | 2279 |
PLRG1,FARSA,NOP16,ETF1,SSBP1,FXN,PPA1,LONP1,IPO11,HMGCR,FAM98A,WDR61,ITPA,POLA1,CPOX,LGALS1,MARCKSL1,MRPS10,PSMA1,C1orf174,TARS,MRPL36,EXO1,CDC16,MTHFD2,KPNA3,COPS5,CUL2,SQLE,NCBP2,ZRANB2,NDUFS5,GCSH |
| 4.553e-02 | -3.09 | aminoacyl-tRNA editing activity | molecular function | GO:0002161 | 11 | 4 | 16491 | 2164 |
VARS,DTD1,LARS2,AARS |
| 4.553e-02 | -3.09 | 1-acylglycerol-3-phosphate O-acyltransferase activity | molecular function | GO:0003841 | 11 | 4 | 16491 | 2164 |
LCLAT1,LPCAT2,AGPAT4,GPAT3 |
| 4.553e-02 | -3.09 | lysophosphatidic acid acyltransferase activity | molecular function | GO:0042171 | 11 | 4 | 16491 | 2164 |
LCLAT1,LPCAT2,AGPAT4,GPAT3 |
| 4.558e-02 | -3.09 | regulation of cellular protein metabolic process | biological process | GO:0032268 | 2389 | 337 | 16441 | 2138 |
PRKAB2,CHAC1,CCNL2,PRKCA,LPAR3,AARS,UBR5,NOS1AP,SKI,TOM1L1,NEK6,PMAIP1,ZFYVE28,MAD1L1,RNF111,FNIP2,HRG,EIF4E3,NRAS,C5AR1,DCUN1D5,DDX3X,CCNT1,LSM14A,SH3RF1,ARL6IP5,FIS1,DIRAS1,NRP1,TNFRSF10D,BMI1,SPOCK3,MEF2C,IFT57,EGR1,LARS2,SLK,KHDRBS1,OPHN1,PID1,TGFBR2,PDCD5,ABCA7,IGF2BP3,PRKCE,FKBP1A,CNST,UBE3A,MYC,ANP32B,IGF2BP1,CCDC88C,PRMT5,MAP3K12,CAV2,PABPC1,MYB,HMGCR,ADARB1,PEA15,ZNF675,BDNF,SYNGAP1,WDR61,RB1CC1,EIF4A2,RAP1B,USP10,ARRDC4,PLCB1,ABCF1,ARIH2,IRS1,EPRS,KIDINS220,TRAP1,PMEPA1,CDK9,DPEP1,CNOT6,NCOR1,SMYD3,SPRED2,MAP2K5,BIRC6,PAFAH1B1,DDR2,MYH9,HSPA1A,PAIP2,TERF2IP,SHC1,UCHL5,WAC,SOCS6,MMP14,DTNBP1,SERPINH1,KMT2A,CDK12,PERP,CASP8AP2,BRD4,EIF3J,MTIF2,DLG4,SETD7,STK10,SERP1,FGFR1,SNCA,FBXL5,CAMK2D,CDC16,SMARCC1,NSMCE2,HIPK2,G6PD,DNAJA3,RPS6KB1,ANXA2,MID1,BRAF,GAS6,AKT1S1,IKBKAP,TGFB2,NOL3,RPS6KA5,GIGYF2,FOXO3,PSMF1,MAD2L2,TADA3,ABL1,SNW1,GATC,TRIAP1,RDX,CELF1,YBX3,ERRFI1,LARP4B,MAP3K14,SAMD4A,SPTAN1,FGF9,PXN,ZFYVE1,USP42,NXN,PTK2,IL6R,UBE2K,GUF1,UBC,OXSR1,TRIB3,KLHL22,NSD1,IREB2,ATM,APAF1,PSAP,BMP4,IGBP1,UQCC1,ANAPC4,STK4,EIF3C,UBN1,NF1,PPARGC1B,PTPRA,RCHY1,CSNK2A1,BCOR,SIRT2,NLE1,BIRC2,MAP2K3,SMARCB1,ABL2,ANAPC1,ECM1,RAP1A,ANAPC11,ANAPC10,PCOLCE2,PRKACB,CDC37,TNK2,ATF4,GCNT2,SESN2,PPARG,CDK4,TFPI,HSPA5,ARRDC3,GMFB,SUMO3,BRCA1,CAV1,SOX4,PAF1,ZNF622,EIF4ENIF1,DNAJC1,PER1,EEFSEC,SOCS4,TNFRSF1A,ADAM9,CLU,UQCC2,MTCH1,TNRC6A,USP15,TTN,FN1,FOXO1,TAF1,PAX2,UBXN1,NKD2,SMAD7,LAMTOR3,MAPK8IP3,ZFP36L1,RHBDD1,DDIT4,RNF40,ELL,P3H1,ATXN2,NDRG4,GTF2H1,CTR9,VAPB,WNT16,CAMKK2,CRADD,PAXBP1,USP49,ELP3,WWC1,PSMA1,EIF2A,HERPUD1,ISG15,UBE2E1,SPAG9,SYNCRIP,IRAK2,DTD1,PRKAR2A,TESC,AGO3,BCCIP,USP7,ZNF706,ASH1L,CELSR3,CEMIP,TNXB,PPP2R2A,RIPK1,CSTA,PIBF1,KDM1A,MPHOSPH10,SOCS1,GRIN2C,DNAJB6,IKBKB,ETF1,FHIT,PRMT3,CASP10,HTRA2,KIRREL2,C1QTNF1,AKAP13,ENC1,USP36,EIF3H,PUM3,SMAD3,ADNP,COPS5,KLF4,ATG7,DUSP19,USP11,EIF2B3,PARD3,PKIB,TNIK,NIFK,MINK1,MIF4GD,MAP3K13,SUPT6H,CAMK1,AGO2,IGF2BP2,VARS,PPP1R1C,BMP6,SFI1,ANKRD54,PTPN2,SELT,FBXO31,CD44,RPS6KB2,FGF2,CRIM1,KDM5A,TEX14,MEN1,EIF5B,SYMPK,PIK3CB,CTIF,HSPA1B,DKK1,GADD45A,SET,GLG1,EIF2S1,USP20,NCBP2,RBM26,NR2F2,ZAK |
| 4.563e-02 | -3.09 | ZMYM2 (zinc finger, MYM-type 2) | protein interactions | 7750 | 45 | 11 | 16036 | 2270 |
SMAD3,UBTF,SKIL,RAD18,SREBF2,NUP133,HNRNPH3,ZNF512B,FUS,KDM1A,USP15 |
| 4.563e-02 | -3.09 | INTS1 (integrator complex subunit 1) | protein interactions | 26173 | 45 | 11 | 16036 | 2270 |
DEAF1,INTS7,INTS5,ASUN,SIRT7,INTS9,INTS12,C7orf26,POLR2A,CPSF3L,RPA1 |
| 4.567e-02 | -3.09 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP | 171 | 30 | 17758 | 2279 |
SLC37A3,PPARG,MYO7A,KIAA0586,RNF24,SSBP2,AP1B1,TMEM187,SLC26A11,ETFB,PYCR1,OSBPL1A,TADA3,CAMK2D,ACD,SOCS1,LRP2BP,MCM5,C12orf76,PTPN4,SLC25A11,MED20,MAP3K14,LRSAM1,VCL,ZNF589,PDE9A,C6orf89,RAB30,RPS6KB2 |
| 4.567e-02 | -3.09 | MORF_HAT1 | MSigDB lists | MORF_HAT1 | 171 | 30 | 17758 | 2279 |
RFC4,IFRD1,PRPF31,KHDRBS1,ALG8,R3HDM1,SMG7,RTN4,XPO7,TARS,HDDC2,POM121,UBE2E1,RPA1,NDUFB3,NDUFV1,HNRNPR,COPS5,BANF1,SET,CEBPZ,UBAP2L,GPN1,SSBP1,POLE3,AP2S1,GNG5,HNRNPM,MTHFD1,NUDC |
| 4.572e-02 | -3.09 | EPB41L3 (erythrocyte membrane protein band 4.1-like 3) | protein interactions | 23136 | 90 | 19 | 16036 | 2270 |
SIRT7,ZC3H18,WWC1,CSNK2A1,PLA2G12A,WDR26,PNN,DKC1,PIP4K2A,CLNS1A,TAF2,DDAH2,CWC27,UNC13A,ASB3,ZRANB2,PRMT5,CD44,SRRM2 |
| 4.572e-02 | -3.09 | NCK1 (NCK adaptor protein 1) | protein interactions | 4690 | 90 | 19 | 16036 | 2270 |
TNK2,TNIK,PXN,MINK1,TUBA1A,KHDRBS1,HSPA5,ARHGAP32,PTK2,FGFR1,PHC2,ABL1,RHOU,EIF2S2,SOCS1,NCKIPSD,SYNJ2,SYNPO,CAV2 |
| 4.584e-02 | -3.08 | NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 80 | 16 | 17758 | 2279 |
ZNF254,NR6A1,CUX1,NFX1,HDAC8,PRDM1,MEN1,SUPT5H,SMAD3,NSD1,SUPT4H1,VPS72,JAZF1,ZEB1,ZNF148,NRIP1 |
| 4.585e-02 | -3.08 | apical junction complex | cellular component | GO:0043296 | 126 | 23 | 17570 | 2233 |
ARHGAP17,CGN,AMOTL1,CLDN15,ASH1L,JUP,UBN1,CDK4,NHS,SYMPK,RPGRIP1L,CXADR,TJAP1,ESAM,MPP7,PVRL3,MARVELD2,YBX3,MAGI1,VCL,AMOT,SYNPO,PARD3 |
| 4.588e-02 | -3.08 | ear | COSMIC cancer mutations | ear | 642 | 97 | 17775 | 2278 |
BIRC6,UPK3B,SLC5A5,CELSR3,NF1,DDR2,TBCCD1,FOSL2,STK33,SAFB2,DENND3,SYNJ1,UBR5,VPS18,ZNF804A,RPS16,ABCA12,ACD,ZEB1,CCDC40,KDM5C,MEIS3,MET,SRRM2,PLEKHA4,LYST,PTPRK,LAMA4,GDAP1,NRAS,ANK2,SFSWAP,SLCO6A1,TOR1AIP2,LAMA2,KCNH3,KMT2C,DDX60,UBR4,FGFR1,RAD54B,TMEM132B,AHNAK,BRCA2,TRRAP,WDR5B,SUFU,SIX5,CHD3,ITGA2,LARGE,TSSC1,VPS13D,ZBTB11,SMG1,TNRC6A,MEF2C,CADM4,AOC3,BRAF,MAP3K13,ZHX3,PIK3R4,IGF2BP2,EVPL,FOXO3,NDUFV1,STC2,PRICKLE2,PTGS1,SYNJ2,CNOT4,NT5E,SCAF11,SIK3,DNMBP,AGPAT4,PSPC1,UTP15,ARID1A,LENG8,PALLD,EHBP1,CPT1A,PIK3CB,NCDN,ATP9B,LRP1B,MYBBP1A,POLE2,VCAN,MED15,TBX3,EXOC4,ATM,BPNT1,GCSH |
| 4.593e-02 | -3.08 | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | MSigDB lists | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | 99 | 19 | 17758 | 2279 |
BCCIP,RFC4,CDK4,FANCD2,SMARCA4,CSNK2A1,MLH1,MAP2K3,RPA1,SMAD3,ABL1,BRCA2,RBBP8,TP53BP1,MYC,E2F4,H2AFX,ATM,TERF2 |
| 4.593e-02 | -3.08 | ACTWSNACTNY_UNKNOWN | MSigDB lists | ACTWSNACTNY_UNKNOWN | 99 | 19 | 17758 | 2279 |
BCKDK,HMBOX1,MPP6,FOXO1,ZCCHC8,CA11,POLK,ZC4H2,COL4A3BP,TOP3A,ZNF691,AHCYL2,ARMC5,INTS9,HIRIP3,FNTB,FHIT,CNOT4,ANKS1A |
| 4.602e-02 | -3.08 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 198 | 34 | 17758 | 2279 |
SERINC5,ID1,SEC24D,PAFAH1B1,SLK,WDR26,FAM49A,POM121,RSPRY1,RNF141,PRKD3,ZKSCAN1,NISCH,PAK1IP1,ZEB1,FNIP2,ZMYM2,PLEKHA2,PRPS1,NT5E,MYB,TNK2,PXN,GCNT2,ARHGAP39,ZNF251,ZNF655,CDC16,STX1A,BDH2,SVIL,IFT140,ADAM9,FNBP1L |
| 4.605e-02 | -3.08 | PcG protein complex | cellular component | GO:0031519 | 44 | 10 | 17570 | 2233 |
PHC2,PCGF3,AEBP2,UBAP2L,CSNK2A1,RNF2,BCOR,BMI1,TRIM37,RING1 |
| 4.609e-02 | -3.08 | NUP153 (nucleoporin 153kDa) | protein interactions | 9972 | 56 | 13 | 16036 | 2270 |
SMAD3,RANBP2,PRKCSH,MYC,SIRT7,XPO5,NFX1,USP20,BRCA1,RAN,FIP1L1,XPO7,USP11 |
| 4.609e-02 | -3.08 | ACLY (ATP citrate lyase) | protein interactions | 47 | 56 | 13 | 16036 | 2270 |
MCM6,CUL7,SHC1,FN1,SIRT6,CUL2,SIRT7,SIRT2,MCM2,UBR4,UBC,ISG15,TERF2 |
| 4.609e-02 | -3.08 | SURF2 (surfeit 2) | protein interactions | 6835 | 56 | 13 | 16036 | 2270 |
POP1,P3H1,LIN28B,ALAD,DDX18,ANKMY2,H2AFX,MINA,GPN1,FTSJ3,PABPC4,TOM1L1,LPP |
| 4.612e-02 | -3.08 | APOPTOSIS_GO | MSigDB lists | APOPTOSIS_GO | 427 | 67 | 17758 | 2279 |
CUL4A,BIRC6,NF1,RIPK1,IKBIP,PRKCA,HSPA1A,CIAPIN1,MRPS30,BRE,ASNS,PMAIP1,DNAJB6,YARS,AVEN,CASP10,CASP8AP2,DDX41,LGALS1,ATG12,MCL1,BRCA1,SON,SAP30BP,ERC1,SNCA,SMAD3,DDAH2,LUC7L3,FIS1,TRAF3,TNFRSF10D,MTCH1,BAG1,BRAF,IFT57,FOXO1,DPF2,MAP1S,RTN4,IP6K2,AKT1S1,TGFB2,NOL3,PDCD7,OPA1,ZNF346,PDCD5,PHLDA2,FOXO3,ABL1,PRKCE,TRIAP1,ANXA5,PEA15,CRADD,RHOT2,SRA1,ANGPTL4,HSPA1B,ANXA1,GADD45A,CUL2,TBX3,APAF1,ZAK,STK4 |
| 4.618e-02 | -3.08 | GOZGIT_ESR1_TARGETS_UP | MSigDB lists | GOZGIT_ESR1_TARGETS_UP | 138 | 25 | 17758 | 2279 |
ACSL5,LAMC1,MMRN2,PPARG,FERMT2,WWC1,FAM13A,GDPD5,FAM49A,TCF7L2,GNAI1,IGF2BP3,OSBPL1A,PTPN2,DST,SUB1,ECM1,DSC2,VWDE,TMEM139,DUSP19,SORCS2,PEG10,CEP170,NT5E |
| 4.618e-02 | -3.08 | GACAATC,MIR-219 | MSigDB lists | GACAATC,MIR-219 | 138 | 25 | 17758 | 2279 |
SYNGAP1,SLK,HOMER2,PHACTR2,AKAP13,MEF2D,TGFBR2,DCBLD2,CHD7,ZNF827,UBE3A,SHC1,INSIG1,NEK6,HAS3,ARID3B,UBR1,LARP4B,NRIP1,KIF1B,FMNL2,PKNOX1,MAPT,SOX6,LPP |
| 4.619e-02 | -3.07 | histone H3 deacetylation | biological process | GO:0070932 | 21 | 6 | 16441 | 2138 |
HDAC8,SIRT2,SIRT6,PER1,SMARCAD1,SIRT7 |
| 4.619e-02 | -3.07 | histone deubiquitination | biological process | GO:0016578 | 21 | 6 | 16441 | 2138 |
USP7,ATXN7,TRRAP,BRCC3,USP49,USP15 |
| 4.619e-02 | -3.07 | ncRNA 3'-end processing | biological process | GO:0043628 | 21 | 6 | 16441 | 2138 |
EXOSC2,EXOSC4,FBL,DKC1,ERI3,ERI1 |
| 4.619e-02 | -3.07 | zinc II ion transmembrane transport | biological process | GO:0071577 | 21 | 6 | 16441 | 2138 |
SLC39A14,SLC30A3,SLC39A1,SLC39A7,SLC39A11,SLC30A7 |
| 4.619e-02 | -3.07 | cerebral cortex neuron differentiation | biological process | GO:0021895 | 21 | 6 | 16441 | 2138 |
HPRT1,DLX2,GDPD5,PAFAH1B1,CHD5,RAC3 |
| 4.619e-02 | -3.07 | ncRNA catabolic process | biological process | GO:0034661 | 21 | 6 | 16441 | 2138 |
POP1,EXOSC2,EXOSC4,DROSHA,LIN28B,DIS3L2 |
| 4.632e-02 | -3.07 | negative regulation of tyrosine phosphorylation of Stat5 protein | biological process | GO:0042524 | 3 | 2 | 16441 | 2138 |
PTPN2,CAV1 |
| 4.632e-02 | -3.07 | regulation of tyrosine phosphorylation of Stat6 protein | biological process | GO:0042525 | 3 | 2 | 16441 | 2138 |
PTPN2,PIBF1 |
| 4.632e-02 | -3.07 | ferrous iron transmembrane transport | biological process | GO:1903874 | 3 | 2 | 16441 | 2138 |
SLC39A14,SLC40A1 |
| 4.632e-02 | -3.07 | negative regulation of protein import into nucleus, translocation | biological process | GO:0033159 | 3 | 2 | 16441 | 2138 |
GAS6,PDE2A |
| 4.632e-02 | -3.07 | positive regulation of nucleobase-containing compound transport | biological process | GO:0032241 | 3 | 2 | 16441 | 2138 |
NCBP2,KHDRBS1 |
| 4.632e-02 | -3.07 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological process | GO:1903026 | 3 | 2 | 16441 | 2138 |
ID1,DDIT3 |
| 4.632e-02 | -3.07 | farnesyl diphosphate metabolic process | biological process | GO:0045338 | 3 | 2 | 16441 | 2138 |
FDPS,FDFT1 |
| 4.632e-02 | -3.07 | negative regulation of mitochondrial membrane permeability | biological process | GO:0035795 | 3 | 2 | 16441 | 2138 |
NOL3,HK2 |
| 4.632e-02 | -3.07 | embryonic nail plate morphogenesis | biological process | GO:0035880 | 3 | 2 | 16441 | 2138 |
MSX2,MSX1 |
| 4.632e-02 | -3.07 | pentose-phosphate shunt, oxidative branch | biological process | GO:0009051 | 3 | 2 | 16441 | 2138 |
G6PD,PGD |
| 4.632e-02 | -3.07 | adenine salvage | biological process | GO:0006168 | 3 | 2 | 16441 | 2138 |
APRT,HPRT1 |
| 4.632e-02 | -3.07 | regulation of hyaluranon cable assembly | biological process | GO:1900104 | 3 | 2 | 16441 | 2138 |
HYAL1,HAS3 |
| 4.632e-02 | -3.07 | vitamin D receptor signaling pathway | biological process | GO:0070561 | 3 | 2 | 16441 | 2138 |
VDR,CYP24A1 |
| 4.632e-02 | -3.07 | positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | GO:0070434 | 3 | 2 | 16441 | 2138 |
HSPA1A,HSPA1B |
| 4.632e-02 | -3.07 | blastocyst hatching | biological process | GO:0001835 | 3 | 2 | 16441 | 2138 |
RBBP8,SMARCB1 |
| 4.632e-02 | -3.07 | positive regulation of nucleotide-binding oligomerization domain containing signaling pathway | biological process | GO:0070426 | 3 | 2 | 16441 | 2138 |
HSPA1A,HSPA1B |
| 4.632e-02 | -3.07 | blood vessel endothelial cell fate commitment | biological process | GO:0060846 | 3 | 2 | 16441 | 2138 |
RBPJ,NRP1 |
| 4.632e-02 | -3.07 | hypoxia-inducible factor-1alpha signaling pathway | biological process | GO:0097411 | 3 | 2 | 16441 | 2138 |
PDK1,HIF1A |
| 4.632e-02 | -3.07 | regulation of membrane repolarization during action potential | biological process | GO:0098903 | 3 | 2 | 16441 | 2138 |
CAV1,NOS1AP |
| 4.632e-02 | -3.07 | regulation of cellular response to drug | biological process | GO:2001038 | 3 | 2 | 16441 | 2138 |
HMGA2,KMT2A |
| 4.632e-02 | -3.07 | cellular response to cycloheximide | biological process | GO:0071409 | 3 | 2 | 16441 | 2138 |
KLF6,KLF4 |
| 4.632e-02 | -3.07 | nitric oxide homeostasis | biological process | GO:0033484 | 3 | 2 | 16441 | 2138 |
CAV1,ADNP |
| 4.632e-02 | -3.07 | riboflavin transport | biological process | GO:0032218 | 3 | 2 | 16441 | 2138 |
SLC52A2,SLC52A3 |
| 4.632e-02 | -3.07 | protein localization to endoplasmic reticulum exit site | biological process | GO:0070973 | 3 | 2 | 16441 | 2138 |
BCAP29,GBF1 |
| 4.632e-02 | -3.07 | 'de novo' UMP biosynthetic process | biological process | GO:0044205 | 3 | 2 | 16441 | 2138 |
CAD,UMPS |
| 4.632e-02 | -3.07 | trunk neural crest cell migration | biological process | GO:0036484 | 3 | 2 | 16441 | 2138 |
SEMA3F,NRP1 |
| 4.632e-02 | -3.07 | histone H2A phosphorylation | biological process | GO:1990164 | 3 | 2 | 16441 | 2138 |
HMGA2,RPS6KA5 |
| 4.632e-02 | -3.07 | positive regulation of mesenchymal cell apoptotic process | biological process | GO:2001055 | 3 | 2 | 16441 | 2138 |
MSX2,MSX1 |
| 4.632e-02 | -3.07 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay | biological process | GO:0031086 | 3 | 2 | 16441 | 2138 |
DCP1B,EDC3 |
| 4.632e-02 | -3.07 | asparaginyl-tRNA aminoacylation | biological process | GO:0006421 | 3 | 2 | 16441 | 2138 |
NARS2,NARS |
| 4.632e-02 | -3.07 | endocytosis involved in viral entry into host cell | biological process | GO:0075509 | 3 | 2 | 16441 | 2138 |
CAV1,CAV2 |
| 4.632e-02 | -3.07 | GDP-L-fucose metabolic process | biological process | GO:0046368 | 3 | 2 | 16441 | 2138 |
GMDS,TSTA3 |
| 4.632e-02 | -3.07 | regulation of gluconeogenesis involved in cellular glucose homeostasis | biological process | GO:0090526 | 3 | 2 | 16441 | 2138 |
RANBP2,SESN2 |
| 4.632e-02 | -3.07 | regulation of AV node cell action potential | biological process | GO:0098904 | 3 | 2 | 16441 | 2138 |
RYR2,ANK2 |
| 4.632e-02 | -3.07 | blood vessel endothelial cell fate specification | biological process | GO:0097101 | 3 | 2 | 16441 | 2138 |
RBPJ,NRP1 |
| 4.632e-02 | -3.07 | vestibulocochlear nerve morphogenesis | biological process | GO:0021648 | 3 | 2 | 16441 | 2138 |
NRP1,PAX2 |
| 4.632e-02 | -3.07 | histone H3-K36 dimethylation | biological process | GO:0097676 | 3 | 2 | 16441 | 2138 |
ASH1L,SETD2 |
| 4.632e-02 | -3.07 | negative regulation of cellular respiration | biological process | GO:1901856 | 3 | 2 | 16441 | 2138 |
TRAP1,SNCA |
| 4.632e-02 | -3.07 | receptor-mediated endocytosis of virus by host cell | biological process | GO:0019065 | 3 | 2 | 16441 | 2138 |
CAV1,CAV2 |
| 4.632e-02 | -3.07 | regulation of atrial cardiac muscle cell action potential | biological process | GO:0098910 | 3 | 2 | 16441 | 2138 |
RYR2,ANK2 |
| 4.632e-02 | -3.07 | ventral trunk neural crest cell migration | biological process | GO:0036486 | 3 | 2 | 16441 | 2138 |
SEMA3F,NRP1 |
| 4.632e-02 | -3.07 | positive regulation of transcription during mitosis | biological process | GO:0045897 | 3 | 2 | 16441 | 2138 |
TCF7L1,SIRT7 |
| 4.632e-02 | -3.07 | germ cell proliferation | biological process | GO:0036093 | 3 | 2 | 16441 | 2138 |
EIF2S2,DMRT1 |
| 4.632e-02 | -3.07 | mitotic sister chromatid separation | biological process | GO:0051306 | 3 | 2 | 16441 | 2138 |
TEX14,DIS3L2 |
| 4.632e-02 | -3.07 | positive regulation of glucose mediated signaling pathway | biological process | GO:1902661 | 3 | 2 | 16441 | 2138 |
SMARCA4,SMARCB1 |
| 4.632e-02 | -3.07 | trunk segmentation | biological process | GO:0035290 | 3 | 2 | 16441 | 2138 |
SEMA3F,NRP1 |
| 4.632e-02 | -3.07 | optic cup formation involved in camera-type eye development | biological process | GO:0003408 | 3 | 2 | 16441 | 2138 |
ARID1A,WNT16 |
| 4.632e-02 | -3.07 | regulation of mitochondrial DNA replication | biological process | GO:0090296 | 3 | 2 | 16441 | 2138 |
PID1,STOML2 |
| 4.632e-02 | -3.07 | organism emergence from protective structure | biological process | GO:0071684 | 3 | 2 | 16441 | 2138 |
RBBP8,SMARCB1 |
| 4.632e-02 | -3.07 | hatching | biological process | GO:0035188 | 3 | 2 | 16441 | 2138 |
RBBP8,SMARCB1 |
| 4.632e-02 | -3.07 | positive regulation of hyaluranon cable assembly | biological process | GO:1900106 | 3 | 2 | 16441 | 2138 |
HYAL1,HAS3 |
| 4.632e-02 | -3.07 | depurination | biological process | GO:0045007 | 3 | 2 | 16441 | 2138 |
OGG1,MUTYH |
| 4.632e-02 | -3.07 | deadenylation-independent decapping of nuclear-transcribed mRNA | biological process | GO:0031087 | 3 | 2 | 16441 | 2138 |
DCP1B,EDC3 |
| 4.632e-02 | -3.07 | glutamine catabolic process | biological process | GO:0006543 | 3 | 2 | 16441 | 2138 |
GLS,PPAT |
| 4.632e-02 | -3.07 | maintenance of Golgi location | biological process | GO:0051684 | 3 | 2 | 16441 | 2138 |
TBCCD1,ARHGAP21 |
| 4.632e-02 | -3.07 | alanyl-tRNA aminoacylation | biological process | GO:0006419 | 3 | 2 | 16441 | 2138 |
AARS,AARS2 |
| 4.632e-02 | -3.07 | D-xylose metabolic process | biological process | GO:0042732 | 3 | 2 | 16441 | 2138 |
XYLB,DCXR |
| 4.632e-02 | -3.07 | arginyl-tRNA aminoacylation | biological process | GO:0006420 | 3 | 2 | 16441 | 2138 |
RARS,RARS2 |
| 4.632e-02 | -3.07 | positive regulation of catagen | biological process | GO:0051795 | 3 | 2 | 16441 | 2138 |
MSX2,TGFB2 |
| 4.638e-02 | -3.07 | protein modification by small protein conjugation | biological process | GO:0032446 | 726 | 110 | 16441 | 2138 |
MYCBP2,CUL7,CUL4A,FEM1C,BIRC6,HECTD3,RCHY1,KLHL18,RNF24,RNF43,BCOR,HLTF,NUP43,NUP160,BIRC2,UBR5,RING1,PHC2,ANAPC1,KCTD11,SOCS1,NUP133,UBR1,ATG3,WAC,ANAPC11,ANAPC10,SOCS6,TRIML2,RNF111,IPP,TTC3,RNF2,SEH1L,PRPF19,TRIM13,RBCK1,KLHL23,MED27,TCEB3,SUMO3,MARCH6,DCUN1D5,BRCA1,ENC1,NUP214,UBR4,SPOP,PAF1,FBXL5,RANBP2,UBE3D,CDC16,RAD18,SH3RF1,NSMCE1,NSMCE2,SOCS4,ATG7,TRAF3,ASB3,RNF130,MED20,CCNB1IP1,XRCC4,BLMH,BMI1,DCAF5,TRIM36,KLHL24,FBXO45,CTU2,HERC2,XPC,TRIM22,CDC73,PSMF1,NEDD4,POM121,RNF40,RNF141,UBE3A,PPIL2,MED24,CTR9,LTN1,FBXO31,CNOT4,LRSAM1,FBXL19,MARCH9,STAG1,ANAPC13,PSMA1,SCMH1,UBE2K,TRIM37,UBC,ARIH2,UBE2E1,RPA1,FBXO21,KLHL22,HERC1,CUL2,RNF138,C18orf25,ANAPC4,LRRC41,RNF114 |
| 4.642e-02 | -3.07 | FDF | pfam domains | PF09532 | 3 | 2 | 16629 | 2165 |
LSM14A,EDC3 |
| 4.642e-02 | -3.07 | TatD_DNase | pfam domains | PF01026 | 3 | 2 | 16629 | 2165 |
TATDN1,TATDN3 |
| 4.642e-02 | -3.07 | RNA_pol_Rpb2_3 | pfam domains | PF04565 | 3 | 2 | 16629 | 2165 |
POLR1B,POLR3B |
| 4.642e-02 | -3.07 | DUF1087 | pfam domains | PF06465 | 3 | 2 | 16629 | 2165 |
CHD3,CHD5 |
| 4.642e-02 | -3.07 | DALR_1 | pfam domains | PF05746 | 3 | 2 | 16629 | 2165 |
RARS,RARS2 |
| 4.642e-02 | -3.07 | Sec16_C | pfam domains | PF12931 | 3 | 2 | 16629 | 2165 |
SEC31A,SEC16A |
| 4.642e-02 | -3.07 | CPT_N | pfam domains | PF16484 | 3 | 2 | 16629 | 2165 |
CPT1A,CPT1C |
| 4.642e-02 | -3.07 | AIRS | pfam domains | PF00586 | 3 | 2 | 16629 | 2165 |
SEPHS2,GART |
| 4.642e-02 | -3.07 | CHDNT | pfam domains | PF08073 | 3 | 2 | 16629 | 2165 |
CHD3,CHD5 |
| 4.642e-02 | -3.07 | VPS13 | pfam domains | PF16908 | 3 | 2 | 16629 | 2165 |
VPS13D,VPS13C |
| 4.642e-02 | -3.07 | P5CR_dimer | pfam domains | PF14748 | 3 | 2 | 16629 | 2165 |
PYCRL,PYCR1 |
| 4.642e-02 | -3.07 | 4F5 | pfam domains | PF04419 | 3 | 2 | 16629 | 2165 |
ZNF706,SERF2 |
| 4.642e-02 | -3.07 | FGF-BP1 | pfam domains | PF06473 | 3 | 2 | 16629 | 2165 |
FGFBP1,FGFBP3 |
| 4.642e-02 | -3.07 | tRNA_m1G_MT | pfam domains | PF01746 | 3 | 2 | 16629 | 2165 |
TRMT10B,TRMT10A |
| 4.642e-02 | -3.07 | TBD | pfam domains | PF12845 | 3 | 2 | 16629 | 2165 |
TBKBP1,TANK |
| 4.642e-02 | -3.07 | Abhydrolase_2 | pfam domains | PF02230 | 3 | 2 | 16629 | 2165 |
LYPLAL1,LYPLA2 |
| 4.642e-02 | -3.07 | RFX1_trans_act | pfam domains | PF04589 | 3 | 2 | 16629 | 2165 |
RFX1,RFX2 |
| 4.642e-02 | -3.07 | RNA_pol_Rpb2_2 | pfam domains | PF04561 | 3 | 2 | 16629 | 2165 |
POLR1B,POLR3B |
| 4.642e-02 | -3.07 | RNA_pol_Rpb2_1 | pfam domains | PF04563 | 3 | 2 | 16629 | 2165 |
POLR1B,POLR3B |
| 4.642e-02 | -3.07 | RMMBL | pfam domains | PF07521 | 3 | 2 | 16629 | 2165 |
CPSF3,CPSF3L |
| 4.642e-02 | -3.07 | Methyltransf_12 | pfam domains | PF08242 | 3 | 2 | 16629 | 2165 |
METTL6,METTL8 |
| 4.642e-02 | -3.07 | LNS2 | pfam domains | PF08235 | 3 | 2 | 16629 | 2165 |
LPIN2,LPIN1 |
| 4.642e-02 | -3.07 | MGS | pfam domains | PF02142 | 3 | 2 | 16629 | 2165 |
CAD,ATIC |
| 4.642e-02 | -3.07 | B2-adapt-app_C | pfam domains | PF09066 | 3 | 2 | 16629 | 2165 |
AP1B1,AP4B1 |
| 4.642e-02 | -3.07 | VPS13_mid_rpt | pfam domains | PF16910 | 3 | 2 | 16629 | 2165 |
VPS13D,VPS13C |
| 4.642e-02 | -3.07 | PHD_4 | pfam domains | PF16866 | 3 | 2 | 16629 | 2165 |
KDM2A,FBXL19 |
| 4.642e-02 | -3.07 | FOXO-TAD | pfam domains | PF16676 | 3 | 2 | 16629 | 2165 |
FOXO1,FOXO3 |
| 4.642e-02 | -3.07 | BRCT_2 | pfam domains | PF16589 | 3 | 2 | 16629 | 2165 |
PES1,TERF2IP |
| 4.642e-02 | -3.07 | tRNA-synt_2c | pfam domains | PF01411 | 3 | 2 | 16629 | 2165 |
AARS,AARS2 |
| 4.642e-02 | -3.07 | AdoHcyase | pfam domains | PF05221 | 3 | 2 | 16629 | 2165 |
AHCYL1,AHCYL2 |
| 4.642e-02 | -3.07 | NHS | pfam domains | PF15273 | 3 | 2 | 16629 | 2165 |
NHSL1,NHS |
| 4.642e-02 | -3.07 | GCFC | pfam domains | PF07842 | 3 | 2 | 16629 | 2165 |
PAXBP1,TFIP11 |
| 4.642e-02 | -3.07 | LSM14 | pfam domains | PF12701 | 3 | 2 | 16629 | 2165 |
LSM14A,EDC3 |
| 4.642e-02 | -3.07 | Cul7 | pfam domains | PF11515 | 3 | 2 | 16629 | 2165 |
HERC2,CUL7 |
| 4.642e-02 | -3.07 | CHDCT2 | pfam domains | PF08074 | 3 | 2 | 16629 | 2165 |
CHD3,CHD5 |
| 4.642e-02 | -3.07 | DUF1011 | pfam domains | PF06237 | 3 | 2 | 16629 | 2165 |
SLC52A2,SLC52A3 |
| 4.642e-02 | -3.07 | Cu_amine_oxidN2 | pfam domains | PF02727 | 3 | 2 | 16629 | 2165 |
AOC3,AOC2 |
| 4.642e-02 | -3.07 | RNA_pol_Rpb2_6 | pfam domains | PF00562 | 3 | 2 | 16629 | 2165 |
POLR1B,POLR3B |
| 4.642e-02 | -3.07 | CBF | pfam domains | PF03914 | 3 | 2 | 16629 | 2165 |
NOC3L,CEBPZ |
| 4.642e-02 | -3.07 | DUF1086 | pfam domains | PF06461 | 3 | 2 | 16629 | 2165 |
CHD3,CHD5 |
| 4.642e-02 | -3.07 | Lipin_N | pfam domains | PF04571 | 3 | 2 | 16629 | 2165 |
LPIN2,LPIN1 |
| 4.642e-02 | -3.07 | HhH-GPD | pfam domains | PF00730 | 3 | 2 | 16629 | 2165 |
MUTYH,OGG1 |
| 4.642e-02 | -3.07 | Angiomotin_C | pfam domains | PF12240 | 3 | 2 | 16629 | 2165 |
AMOTL1,AMOT |
| 4.642e-02 | -3.07 | Lipin_mid | pfam domains | PF16876 | 3 | 2 | 16629 | 2165 |
LPIN2,LPIN1 |
| 4.642e-02 | -3.07 | AKAP95 | pfam domains | PF04988 | 3 | 2 | 16629 | 2165 |
AKAP8L,ZNF326 |
| 4.642e-02 | -3.07 | VASP_tetra | pfam domains | PF08776 | 3 | 2 | 16629 | 2165 |
ENAH,EVL |
| 4.642e-02 | -3.07 | NAD_binding_2 | pfam domains | PF03446 | 3 | 2 | 16629 | 2165 |
GLYR1,PGD |
| 4.642e-02 | -3.07 | Caveolin | pfam domains | PF01146 | 3 | 2 | 16629 | 2165 |
CAV1,CAV2 |
| 4.642e-02 | -3.07 | RNA_pol_Rpb2_7 | pfam domains | PF04560 | 3 | 2 | 16629 | 2165 |
POLR3B,POLR1B |
| 4.642e-02 | -3.07 | Cu_amine_oxid | pfam domains | PF01179 | 3 | 2 | 16629 | 2165 |
AOC3,AOC2 |
| 4.642e-02 | -3.07 | PRMT5 | pfam domains | PF05185 | 3 | 2 | 16629 | 2165 |
PRMT5,CARM1 |
| 4.642e-02 | -3.07 | Requiem_N | pfam domains | PF14051 | 3 | 2 | 16629 | 2165 |
DPF3,DPF2 |
| 4.642e-02 | -3.07 | Cu_amine_oxidN3 | pfam domains | PF02728 | 3 | 2 | 16629 | 2165 |
AOC3,AOC2 |
| 4.642e-02 | -3.07 | AdoHcyase_NAD | pfam domains | PF00670 | 3 | 2 | 16629 | 2165 |
AHCYL1,AHCYL2 |
| 4.643e-02 | -3.07 | MAPK signaling pathway | KEGG pathways | ko04010 | 255 | 42 | 6908 | 881 |
BRAF,MAP2K5,MAP3K13,NF1,LAMTOR3,MAPK8IP3,CACNA1H,TGFB2,PRKCA,RPS6KA5,TGFBR2,HSPA1A,RAC3,FLNB,MAP2K3,RAP1A,CACNB2,MYC,IKBKB,RELB,MAP3K14,MAP3K12,PRKACB,FLNC,FGF9,BDNF,NRAS,ATF4,FGF2,RAP1B,FGFR1,HSPA1B,CACNB1,GADD45A,TNFRSF1A,PPP3CC,ZAK,MAP2K4,DDIT3,MAPT,STK4,MEF2C |
| 4.643e-02 | -3.07 | MAPK signaling pathway | KEGG pathways | hsa04010 | 255 | 42 | 6908 | 881 |
BRAF,MAP2K5,MAP3K13,NF1,LAMTOR3,MAPK8IP3,CACNA1H,TGFB2,PRKCA,RPS6KA5,TGFBR2,HSPA1A,RAC3,MAP2K3,FLNB,RAP1A,MYC,CACNB2,IKBKB,RELB,MAP3K14,MAP3K12,PRKACB,FLNC,BDNF,FGF9,NRAS,ATF4,FGF2,RAP1B,FGFR1,HSPA1B,CACNB1,GADD45A,TNFRSF1A,PPP3CC,ZAK,MAP2K4,MAPT,DDIT3,MEF2C,STK4 |
| 4.654e-02 | -3.07 | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | 125 | 23 | 17758 | 2279 |
IFNGR2,PTPRA,GPCPD1,PDE4B,SOX4,TGFB2,KLF6,RAB10,ANXA1,CXADR,SPOP,RHOU,TRIB3,DSC2,KLF4,HIPK2,VPS37B,RELB,TRAF3,RBPJ,APAF1,NFKBIB,MGLL |
| 4.658e-02 | -3.07 | internal protein amino acid acetylation | biological process | GO:0006475 | 117 | 22 | 16441 | 2138 |
KAT8,WDR75,EP400,BRD4,TRIM16,TAF1,TCF3,ELP3,ATAT1,CHD5,TADA3,SRCAP,TRRAP,BRCA2,KANSL1,PER1,MED24,POLE3,TAF12,KMT2A,YEATS2,KAT6A |
| 4.659e-02 | -3.07 | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 178 | 31 | 17758 | 2279 |
ACSL5,TRIM13,IFT57,GARS,LYRM4,USP49,UPP1,EYA3,DENND4A,STK10,TCF7L2,ZFAND3,SPAG9,NME7,NEK6,UBAP1,CC2D1B,FMNL1,RRAGA,PMPCA,ANKRD11,BBIP1,WIZ,ETF1,CD44,ITGAX,MGLL,MB21D2,ZNF598,SLC16A10,HRH1 |
| 4.662e-02 | -3.07 | nuclear envelope organization | biological process | GO:0006998 | 73 | 15 | 16441 | 2138 |
RANBP2,NEK6,PAFAH1B1,NUP133,BANF1,ASUN,PPP2R2A,TOR1AIP2,NUP43,PRKCA,NUP160,NUP214,POM121,SEH1L,LPIN1 |
| 4.666e-02 | -3.06 | RPL8 (ribosomal protein L8) | protein interactions | 6132 | 174 | 33 | 16036 | 2270 |
CUL7,EIF3C,FN1,LIN28B,DDX18,ARL15,SIRT7,RPS29,ATF7IP,PABPC4,NOP56,RPS16,GLYR1,HIRIP3,UPF2,FTSJ3,RPS6KB2,DDX24,HSPA5,MINA,C11orf49,DKC1,RBM28,PUM3,ARIH2,POP1,PES1,RPL28,COPS5,CUL2,C7orf50,COPS6,TXN2 |
| 4.668e-02 | -3.06 | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | 205 | 35 | 17758 | 2279 |
FEZ2,FN1,MFGE8,VARS,SSR4,MMP7,ASNS,MCAM,PTRF,ARHGAP1,SERPINH1,MGLL,RPL22L1,TMEM200A,SLC40A1,ANTXR2,MIOS,TFPI,VSNL1,MTHFD1L,SETD7,GPNMB,SYMPK,NR2F1,ANXA1,PXDN,FSCN1,PAM,ABCC3,ANXA2,VASH2,TPM1,ZMAT3,RBP1,PKIB |
| 4.676e-02 | -3.06 | Menarche (age at onset)(PMID:21102462) | GWAS genes | Menarche (age at onset)(PMID:21102462) | 20 | 7 | 2389 | 419 |
ZNF483,KDM3B,LRP1B,IQCH,OLFM2,EEFSEC,TRIM66 |
| 4.681e-02 | -3.06 | response to abiotic stimulus | biological process | GO:0009628 | 1116 | 164 | 16441 | 2138 |
POLB,NF1,TMEM109,FANCD2,PLOD1,SLC29A1,SIRT2,IKBIP,HMOX2,PRKCA,NUP160,BIRC2,ABL2,MMP7,PMAIP1,XRCC2,RELB,HYAL1,ETV1,OGG1,LONP1,SEH1L,PTPRK,DEAF1,TRIM13,ATF4,PPARG,CDK4,EYA3,ABCC2,CAV1,BRCA1,DDX3X,BRCA2,RAD18,GATA6,TP53BP1,PER1,TNFRSF1A,RAD51B,DPP4,TXN2,RBP1,TTN,FOXO1,EGR1,JUP,DNAH1,PITPNM1,RHBDD1,DDIT4,PRKCE,HVCN1,INTS7,COPS3,MYC,NDRG4,TIMELESS,ANGPT2,HMGCR,BDNF,SYNGAP1,CRADD,RDH10,RYR2,LIG4,ANGPTL4,RDH11,CAT,PDLIM1,HIF1A,HMBS,MAP2K4,ZNF516,SLC2A1,NTSR1,NUP43,HSPA1A,RPAIN,KDM1A,BRE,ASNS,SHC1,PPID,NUP133,DNAJB6,VGF,MMP14,CLCN6,KMT2A,SPIDR,HTRA2,CASP8AP2,PDK1,LRRC8A,ATXN1,NUP214,PDE8B,SMAD3,CAMK2D,RANBP2,HYAL3,ALAD,HIPK2,DNAJA3,ATG7,H2AFX,RPS6KB1,EIF2B3,BRCC3,XRCC4,TROVE2,BAG1,DNAJC2,BRAF,DNAJA4,XPC,XRRA1,ID2,AKT1S1,NOL3,TGFB2,BHLHE40,BMP6,POM121,NEDD4,SUV39H2,ANXA7,TMEM161A,STC2,TRIAP1,ACOT11,NLGN3,YBX3,MAP3K14,ERRFI1,UTS2,CLK2,KCNMA1,LDHA,ADSL,IL6R,MEN1,PDE2A,NAPEPLD,UBC,ZRANB3,ANXA1,RPA1,HSPA1B,OXSR1,GADD45A,GPC2,STX1A,CUL2,EIF2S1,FNTB,AEN,ATM,RBPJ,APAF1,BMP4,ZAK,HRH1 |
| 4.684e-02 | -3.06 | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | MSigDB lists | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | 329 | 53 | 17758 | 2279 |
AK2,MINK1,FEM1C,KLHL18,WDR37,RPS6KA5,GABPB2,ANKRD54,MTUS1,SIPA1L3,ZKSCAN1,JAZF1,JOSD1,RAPGEFL1,IGF2BP1,MAP3K14,ETV1,HN1,DDHD1,GATAD2B,AEBP2,CRIM1,RB1CC1,C19orf43,ZNF654,ANK2,RAB7A,KCNMA1,USP42,ZNF512B,ARHGEF10,ATXN1,ZNFX1,RSBN1,MCL1,MBNL2,NAPEPLD,USP46,PHF6,SPOP,HNRNPH3,ZNF436,HIC2,PURB,ADAM9,CNOT6,RUNX1,IQSEC2,ZBTB11,DMTF1,RABEP1,MEF2C,TRIM36 |
| 4.688e-02 | -3.06 | cardiac conduction | biological process | GO:0061337 | 49 | 11 | 16441 | 2138 |
CAMK2D,DSC2,JUP,SCN1B,ANK2,DSG2,RYR2,CAV1,KCNH2,DSP,CXADR |
| 4.688e-02 | -3.06 | regulation of neurotransmitter secretion | biological process | GO:0046928 | 49 | 11 | 16441 | 2138 |
BRAF,RAP1A,STX1A,NF1,UNC13A,RAP1B,DTNBP1,SEPT5,NAPA,MEF2C,SNCA |
| 4.688e-02 | -3.06 | negative regulation of epithelial cell migration | biological process | GO:0010633 | 49 | 11 | 16441 | 2138 |
DLL4,EVL,MAP2K5,MMRN2,FGF2,PTPRM,KLF4,NR2F2,HRG,PTPRG,ANGPT2 |
| 4.692e-02 | -3.06 | PDE4DIP (phosphodiesterase 4D interacting protein) | protein interactions | 9659 | 73 | 16 | 16036 | 2270 |
TNIK,MIF4GD,PRPF31,TFIP11,KLC4,ZNF512B,LAMTOR3,KDM1A,VAC14,SNCA,CCDC146,ANKRD11,AEN,RNF2,CEP170,PRKACB |
| 4.692e-02 | -3.06 | TARS (threonyl-tRNA synthetase) | protein interactions | 6897 | 73 | 16 | 16036 | 2270 |
SNU13,SARS,GARS,CUL7,FN1,HARS,BRCA1,ISG15,TPD52L2,FARSA,AHNAK,SET,RNF2,FUS,TOMM34,NUDC |
| 4.694e-02 | -3.06 | skeletal system development | biological process | GO:0001501 | 471 | 74 | 16441 | 2138 |
PAFAH1B1,PPARGC1B,DDR2,MKS1,PBX1,PRKCA,NLE1,SLC39A1,PLXNB1,SBDS,WNT2B,SKI,CHD7,ACD,ANKRD11,MMP14,ZEB1,HYAL1,SERPINH1,CTC1,CARM1,DEAF1,FBXW4,COL5A2,SATB2,MEF2D,MTHFD1L,SOX4,SLC35D1,FLVCR1,SERP1,FGFR1,SMAD3,VDR,MSX2,HYAL3,SUFU,INSIG1,MBTD1,HOXA3,IFT140,DLX2,RUNX1,ANXA2,MEF2C,HMGA2,CHST11,INSIG2,DYM,BARX2,TGFB2,TGFBR2,FOXP1,PIP4K2A,BMP6,PEX7,P3H1,CD44,SOX6,MTHFD1,FGF9,MSX1,FGF2,RDH10,ARID5B,SETD2,FOXC1,HIF1A,VCAN,TBX3,GLG1,CSRNP1,BMP4,MMP16 |
| 4.696e-02 | -3.06 | CROMER_METASTASIS_UP | MSigDB lists | CROMER_METASTASIS_UP | 74 | 15 | 17758 | 2279 |
FADS1,TCF12,CELSR1,SERINC1,ATRX,PPID,MFGE8,TMEM109,ID2,FERMT2,TMEM123,KDM5C,BMI1,REEP5,PTPRK |
| 4.697e-02 | -3.06 | cystic_tumour | COSMIC cancer mutations | cystic_tumour | 93 | 18 | 17775 | 2278 |
ID1,TTLL5,BRAF,ITFG1,C22orf34,ARFIP2,R3HDM1,RNF43,MON2,SYNJ1,CHAF1A,VCAN,PER1,ANP32B,NFASC,NRP1,VPS13B,MTHFD1 |
| 4.697e-02 | -3.06 | pancreas-other-cystic_tumour | COSMIC cancer mutations | pancreas-other-cystic_tumour | 93 | 18 | 17775 | 2278 |
ID1,TTLL5,BRAF,ITFG1,C22orf34,ARFIP2,R3HDM1,RNF43,MON2,SYNJ1,CHAF1A,VCAN,PER1,ANP32B,NFASC,NRP1,VPS13B,MTHFD1 |
| 4.701e-02 | -3.06 | DNA damage checkpoint | biological process | GO:0000077 | 143 | 26 | 16441 | 2138 |
PEA15,HMGA2,CRADD,XPC,FOXN3,PSMA1,BRCA1,SOX4,PSMF1,GIGYF2,UBC,BRE,RBBP8,NEK6,TP53BP1,INTS7,WAC,TRIAP1,H2AFX,ATRIP,ATM,CEP63,FBXO31,BRCC3,ZAK,PRPF19 |
| 4.707e-02 | -3.06 | glycine metabolic process | biological process | GO:0006544 | 16 | 5 | 16441 | 2138 |
DMGDH,SHMT2,GART,PHGDH,GCSH |
| 4.707e-02 | -3.06 | mitochondrial DNA metabolic process | biological process | GO:0032042 | 16 | 5 | 16441 | 2138 |
SESN2,POLG2,DNAJA3,C10orf2,LONP1 |
| 4.707e-02 | -3.06 | negative regulation of DNA recombination | biological process | GO:0045910 | 16 | 5 | 16441 | 2138 |
TERF2IP,MLH1,RAD18,ZRANB3,MSH3 |
| 4.707e-02 | -3.06 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902043 | 16 | 5 | 16441 | 2138 |
PEA15,SKIL,PMAIP1,NF1,STK4 |
| 4.707e-02 | -3.06 | positive regulation of G2/M transition of mitotic cell cycle | biological process | GO:0010971 | 16 | 5 | 16441 | 2138 |
PBX1,SMARCD3,BRD4,CDK4,RAD51B |
| 4.708e-02 | -3.06 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | 38 | 9 | 17775 | 2278 |
BRAF,NRAS,CLCN6,BCOR,RNF130,MET,KIAA1549,FGFR1,GNAI1 |
| 4.712e-02 | -3.05 | trialkylsulfonium hydrolase activity | molecular function | GO:0016802 | 3 | 2 | 16491 | 2164 |
AHCYL1,AHCYL2 |
| 4.712e-02 | -3.05 | arginine-tRNA ligase activity | molecular function | GO:0004814 | 3 | 2 | 16491 | 2164 |
RARS,RARS2 |
| 4.712e-02 | -3.05 | ferrous iron transmembrane transporter activity | molecular function | GO:0015093 | 3 | 2 | 16491 | 2164 |
SLC39A14,SLC40A1 |
| 4.712e-02 | -3.05 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | molecular function | GO:0004118 | 3 | 2 | 16491 | 2164 |
PDE2A,PDE10A |
| 4.712e-02 | -3.05 | vitamin D response element binding | molecular function | GO:0070644 | 3 | 2 | 16491 | 2164 |
VDR,TCF3 |
| 4.712e-02 | -3.05 | calcium-independent protein kinase C activity | molecular function | GO:0004699 | 3 | 2 | 16491 | 2164 |
PRKCH,PRKCE |
| 4.712e-02 | -3.05 | heteroduplex DNA loop binding | molecular function | GO:0000404 | 3 | 2 | 16491 | 2164 |
XPC,MSH3 |
| 4.712e-02 | -3.05 | Atg8 ligase activity | molecular function | GO:0019776 | 3 | 2 | 16491 | 2164 |
ATG12,ATG3 |
| 4.712e-02 | -3.05 | riboflavin transporter activity | molecular function | GO:0032217 | 3 | 2 | 16491 | 2164 |
SLC52A2,SLC52A3 |
| 4.712e-02 | -3.05 | adenosylhomocysteinase activity | molecular function | GO:0004013 | 3 | 2 | 16491 | 2164 |
AHCYL1,AHCYL2 |
| 4.712e-02 | -3.05 | amidine-lyase activity | molecular function | GO:0016842 | 3 | 2 | 16491 | 2164 |
ADSL,PAM |
| 4.712e-02 | -3.05 | mannose-ethanolamine phosphotransferase activity | molecular function | GO:0051377 | 3 | 2 | 16491 | 2164 |
PIGN,PIGG |
| 4.712e-02 | -3.05 | H3 histone acetyltransferase activity | molecular function | GO:0010484 | 3 | 2 | 16491 | 2164 |
BRCA2,ELP3 |
| 4.712e-02 | -3.05 | tRNA (cytosine) methyltransferase activity | molecular function | GO:0016427 | 3 | 2 | 16491 | 2164 |
METTL2B,METTL2A |
| 4.712e-02 | -3.05 | 1-alkylglycerophosphocholine O-acetyltransferase activity | molecular function | GO:0047192 | 3 | 2 | 16491 | 2164 |
LPCAT1,LPCAT2 |
| 4.712e-02 | -3.05 | endoplasmic reticulum signal peptide binding | molecular function | GO:0030942 | 3 | 2 | 16491 | 2164 |
SRP14,SRP68 |
| 4.712e-02 | -3.05 | histone demethylase activity (H3-dimethyl-K4 specific) | molecular function | GO:0034648 | 3 | 2 | 16491 | 2164 |
KDM5B,KDM1A |
| 4.712e-02 | -3.05 | alanine-tRNA ligase activity | molecular function | GO:0004813 | 3 | 2 | 16491 | 2164 |
AARS,AARS2 |
| 4.712e-02 | -3.05 | succinate-CoA ligase activity | molecular function | GO:0004774 | 3 | 2 | 16491 | 2164 |
SUCLG2,SUCLG1 |
| 4.712e-02 | -3.05 | DNA translocase activity | molecular function | GO:0015616 | 3 | 2 | 16491 | 2164 |
ATRX,RAD54B |
| 4.712e-02 | -3.05 | phosphogluconate dehydrogenase (decarboxylating) activity | molecular function | GO:0004616 | 3 | 2 | 16491 | 2164 |
GLYR1,PGD |
| 4.715e-02 | -3.05 | GTF2I (general transcription factor IIi) | protein interactions | 2969 | 102 | 21 | 16036 | 2270 |
ZBTB17,METTL1,USP7,PGPEP1,AP4S1,SIRT6,SIRT7,LGALS1,ADSL,BRCA1,MAD2L2,KDM1A,POLR2A,CHAF1A,RPA1,WARS,RPL28,MYC,RNF2,SRRM2,RPS6KB2 |
| 4.739e-02 | -3.05 | NOTCH1 Intracellular Domain Regulates Transcription | REACTOME pathways | R-HSA-2122947 | 47 | 11 | 8202 | 1117 |
SNW1,NCOR2,HIF1A,TLE3,MYC,HDAC8,TBL1X,NCOR1,RBPJ,UBC,MAML3 |
| 4.743e-02 | -3.05 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 185 | 32 | 17758 | 2279 |
ADAM19,GDPD5,REEP5,CD226,MFHAS1,IQGAP2,ARHGAP18,PVRL3,CLDND1,VCL,HN1,TMEM200A,SAP30,PEA15,ANTXR2,LDHA,PREX1,LGALS1,TPM4,ATXN1,TTYH2,PHACTR2,COTL1,CRYBG3,USP46,ANXA1,RHOU,PAM,CLU,ANXA2,ZNF532,KIF1B |
| 4.743e-02 | -3.05 | TGASTMAGC_V$NFE2_01 | MSigDB lists | TGASTMAGC_V$NFE2_01 | 185 | 32 | 17758 | 2279 |
RELL2,CLDN15,MMRN2,SEC24D,FAM46B,TNXB,SPATS2,PHLDA2,TTC1,ADCK4,CD44,PEA15,PPP1R9B,FGF9,TEX19,MYO10,RB1CC1,BAZ2A,WDFY3,PRDM1,ARHGAP32,ANGPTL4,NCDN,MFN2,DYNC1H1,VDR,LRP1B,GADD45A,DIRAS1,BLMH,SYNPO,RABEP1 |
| 4.743e-02 | -3.05 | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN | 185 | 32 | 17758 | 2279 |
NCOR2,ASCC1,MAP2K5,TTC27,GPBP1L1,WDR74,POLR1A,SIRT2,C1orf50,GBF1,PRKCE,GATC,PPIL2,ALKBH8,METTL8,MED24,PCK2,FBL,YARS,TRIM14,ELOF1,NIPSNAP1,FAM127A,STAMBP,ZNF467,SEC31A,DCXR,DUSP19,SLCO5A1,MED20,PDCD11,USP15 |
| 4.743e-02 | -3.05 | GSE3982_CTRL_VS_LPS_4H_MAC_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_4H_MAC_UP | 185 | 32 | 17758 | 2279 |
MPI,ASH1L,PCSK7,GIT2,MGA,PHC2,CAD,NUP133,NVL,MRPS27,PRMT5,VCL,BRD4,RFC3,PDE4A,ZNF821,GLTSCR2,ZC4H2,MINA,R3HDM1,IRS1,ADNP,ARNTL,ORC5,HIC2,RBM26,POLR1C,WDR33,BLMH,DOCK6,PRKAR2A,PDSS2 |
| 4.744e-02 | -3.05 | GCM_HDAC1 | MSigDB lists | GCM_HDAC1 | 38 | 9 | 17758 | 2279 |
SCAF11,SRSF2,APEX1,SIGMAR1,TIMM17A,SET,ANP32B,MEN1,HNRNPM |
| 4.747e-02 | -3.05 | artery development | biological process | GO:0060840 | 61 | 13 | 16441 | 2138 |
CHD7,DLL4,JAG1,LUZP1,NF1,SMAD7,PRDM1,BMP4,RBPJ,NRP1,SOX4,FOXC1,KAT6A |
| 4.747e-02 | -3.05 | positive regulation of cellular carbohydrate metabolic process | biological process | GO:0010676 | 61 | 13 | 16441 | 2138 |
PTPN2,IRS1,PRKCE,EPM2AIP1,FOXO1,ENTPD5,PMAIP1,HIF1A,NTSR1,SUPT20H,TCF7L2,HRH1,SNCA |
| 4.751e-02 | -3.05 | GUO_TARGETS_OF_IRS1_AND_IRS2 | MSigDB lists | GUO_TARGETS_OF_IRS1_AND_IRS2 | 93 | 18 | 17758 | 2279 |
MVK,PPARGC1B,RCAN1,IL6R,DKC1,SGK2,CPT1A,SYT1,FLNB,LSS,ATXN2,FDPS,SQLE,SCARB1,DHCR7,FDFT1,LPP,HMGCR |
| 4.758e-02 | -3.05 | spindle | COSMIC cancer mutations | spindle | 393 | 62 | 17775 | 2278 |
XYLB,CGN,AMOTL1,BRAF,PCNT,ARID2,NF1,OSBPL9,NTSR1,LIAS,PTPRG,SYNJ1,UBR5,SMARCB1,IL17RE,ABCA5,SEC24C,ZNHIT6,RNF2,NLGN3,PABPC1,KIAA1549,MPST,HSD17B14,VOPP1,DDHD1,KDM3B,RANBP6,SLC38A6,TNK2,EVL,TRAPPC9,NRAS,MIOS,ZFYVE1,KCNMA1,VWCE,MCL1,KCNH3,EXOG,GPNMB,FLVCR1,MAK16,FGFR1,ANXA1,DCBLD2,RETSAT,SPAG9,MYBBP1A,SUFU,CTAGE5,VPS13D,MYOM2,ANXA2,FUS,MTMR1,PPIL3,NUDT22,ANAPC4,SMG1,USP15,COG5 |
| 4.767e-02 | -3.04 | - | gene3d domains | 1.25.40.180 | 15 | 5 | 9988 | 1398 |
UPF2,MIF4GD,BZW2,CTIF,NOM1 |
| 4.767e-02 | -3.04 | - | gene3d domains | 3.30.1490.20 | 15 | 5 | 9988 | 1398 |
CAD,SUCLG2,GART,SYN2,PCCA |
| 4.779e-02 | -3.04 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | 165 | 29 | 17758 | 2279 |
VIPR1,CARS,OXNAD1,PDK1,FOXO1,SFXN4,TCF3,GNG7,RFX2,KRTCAP3,MRRF,OBSCN,IL6R,PRKCA,FOXP1,SERP1,FLNB,IRS1,C6orf48,TSEN2,TNFRSF10D,TBXA2R,PLEKHG4,CEP170,PDE9A,SLC16A10,NT5E,FAM184A,MYB |
| 4.783e-02 | -3.04 | MORF_FDXR | MSigDB lists | MORF_FDXR | 219 | 37 | 17758 | 2279 |
ATRX,PRKCSH,FAM189B,SLC2A1,KLHL18,CSNK2A1,TTI1,PARN,PITPNM1,JAG1,TBC1D22A,MYC,PPIL2,NCKIPSD,CEP135,RPS6KB2,KAT8,GTF2H3,SIK3,MSX1,SETD1B,LSM12,SFSWAP,EIF5B,PIK3CB,RERE,MFN2,TAF2,HTR7,RANBP2,SLC30A3,RBBP8,CHD3,CRCP,SLC25A11,NFRKB,MUTYH |
| 4.787e-02 | -3.04 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 | 267 | 44 | 17758 | 2279 |
DMXL2,CHST11,CDC42EP2,NF1,STXBP6,ST6GAL1,MED13L,CSNK2A1,ZFP36L1,SPATS2L,SSR4,KCNJ14,NLE1,RPAIN,SLC1A1,PTPN2,ABCA12,NEBL,MBD2,MMP14,CEP135,SEC24A,ARHGAP17,DTNB,TRAPPC9,PDK1,CRADD,EPS15L1,DLG4,ATP6V0A1,PRDM1,RABAC1,HERPUD1,ZBTB25,MGAT2,MSX2,DNAJC1,CAMKMT,BBIP1,VPS13D,ABCC3,ITGB4,SLC43A1,LRRC41 |
| 4.788e-02 | -3.04 | Transport of Mature mRNAs Derived from Intronless Transcripts | REACTOME pathways | R-HSA-159234 | 36 | 9 | 8202 | 1117 |
RANBP2,NUP133,NCBP2,NUP43,CPSF3,NUP160,NUP214,SEH1L,POM121 |
| 4.791e-02 | -3.04 | Spermidine and Spermine Biosynthesis | SMPDB pathways | SMP00445 | 6 | 3 | 978 | 148 |
SRM,ODC1,MAT2A |
| 4.794e-02 | -3.04 | GTATGAT,MIR-154,MIR-487 | MSigDB lists | GTATGAT,MIR-154,MIR-487 | 68 | 14 | 17758 | 2279 |
SPRED2,GPM6A,KPNA3,CLK1,ARID2,TEAD1,KCNMA1,SMAD7,CSMD3,SEMA3C,ARID1A,BMI1,ETV1,TOP1 |
| 4.794e-02 | -3.04 | chr1q22 | MSigDB lists | chr1q22 | 68 | 14 | 17758 | 2279 |
FLAD1,TMCO1,PIGM,ASH1L,GON4L,FDPS,MEX3A,POU2F1,DPM3,SLC25A44,KRTCAP2,SLC50A1,GPATCH4,SKI |
| 4.794e-02 | -3.04 | PID_TELOMERASE_PATHWAY | MSigDB lists | PID_TELOMERASE_PATHWAY | 68 | 14 | 17758 | 2279 |
TERF2IP,SMAD3,ABL1,UBE3A,ACD,PARP2,MYC,ATM,ZNFX1,RPS6KB1,DKC1,NR2F2,TERF2,SAP30 |
| 4.794e-02 | -3.04 | LIU_COMMON_CANCER_GENES | MSigDB lists | LIU_COMMON_CANCER_GENES | 68 | 14 | 17758 | 2279 |
SPG21,SYNCRIP,NSMCE2,ZNF160,DLGAP4,ATP6V0A1,NLN,ATF7IP,POLR1B,ERC1,SERP1,FGFR1,RDH11,NOP56 |
| 4.794e-02 | -3.04 | ROSS_AML_OF_FAB_M7_TYPE | MSigDB lists | ROSS_AML_OF_FAB_M7_TYPE | 68 | 14 | 17758 | 2279 |
TNIK,DNM3,CTNNBL1,ABCC4,STXBP6,VPS37B,UROD,SQLE,RDX,PTGS1,HLTF,TPM1,KCNH2,PDLIM5 |
| 4.795e-02 | -3.04 | NIF3L1 (NIF3 NGG1 interacting factor 3-like 1) | protein interactions | 60491 | 114 | 23 | 16036 | 2270 |
METTL1,SYT17,DDX19A,ACTR3,LAMTOR3,RANGAP1,VIM,RABAC1,NOL3,ENOX1,CUTC,AARS,RAD54B,SH3GL1,TOM1L1,DCTPP1,TPD52L2,ORC5,VPS37B,CCDC85B,TRIP13,BAG1,LPP |
| 4.795e-02 | -3.04 | UBE2E1 (ubiquitin conjugating enzyme E2E 1) | protein interactions | 7324 | 114 | 23 | 16036 | 2270 |
USP7,ATXN1,RNF43,BRCA1,TRIM37,CBWD5,RING1,NEDD4,ARIH2,UBE2E1,RNF40,PAF1,ZNF827,UBE3A,RNF111,CTR9,RNF2,RNF130,CNOT4,LRSAM1,MID1,IPO11,RNF114 |
| 4.796e-02 | -3.04 | PRE_SET | prosite domains | PS50867 | 7 | 3 | 11866 | 1504 |
SUV39H2,EHMT2,EHMT1 |
| 4.796e-02 | -3.04 | GP_PDE | prosite domains | PS51704 | 7 | 3 | 11866 | 1504 |
GDPD5,GDPD1,GPCPD1 |
| 4.796e-02 | -3.04 | SIRTUIN | prosite domains | PS50305 | 7 | 3 | 11866 | 1504 |
SIRT2,SIRT6,SIRT7 |
| 4.796e-02 | -3.04 | G_CP | prosite domains | PS51721 | 7 | 3 | 11866 | 1504 |
GNL1,LSG1,GNL3 |
| 4.796e-02 | -3.04 | DUSP | prosite domains | PS51283 | 7 | 3 | 11866 | 1504 |
USP20,USP11,USP15 |
| 4.796e-02 | -3.04 | ZF_UBR | prosite domains | PS51157 | 7 | 3 | 11866 | 1504 |
UBR1,UBR4,UBR5 |
| 4.796e-02 | -3.04 | CUT | prosite domains | PS51042 | 7 | 3 | 11866 | 1504 |
SATB2,ONECUT2,CUX1 |
| 4.798e-02 | -3.04 | zinc ion transmembrane transporter activity | molecular function | GO:0005385 | 21 | 6 | 16491 | 2164 |
SLC39A14,SLC30A3,SLC39A1,SLC39A7,SLC30A7,SLC39A11 |
| 4.805e-02 | -3.04 | PROGRAMMED_CELL_DEATH | MSigDB lists | PROGRAMMED_CELL_DEATH | 428 | 67 | 17758 | 2279 |
CUL4A,BIRC6,NF1,RIPK1,IKBIP,PRKCA,HSPA1A,CIAPIN1,MRPS30,BRE,ASNS,PMAIP1,DNAJB6,YARS,AVEN,CASP10,CASP8AP2,DDX41,LGALS1,ATG12,MCL1,BRCA1,SON,SAP30BP,ERC1,SNCA,SMAD3,DDAH2,LUC7L3,FIS1,TRAF3,TNFRSF10D,MTCH1,BAG1,BRAF,IFT57,FOXO1,DPF2,MAP1S,RTN4,IP6K2,AKT1S1,TGFB2,NOL3,PDCD7,OPA1,ZNF346,PDCD5,PHLDA2,FOXO3,ABL1,PRKCE,TRIAP1,ANXA5,PEA15,CRADD,RHOT2,SRA1,ANGPTL4,HSPA1B,ANXA1,GADD45A,CUL2,TBX3,APAF1,ZAK,STK4 |
| 4.807e-02 | -3.04 | response to oxygen levels | biological process | GO:0070482 | 291 | 48 | 16441 | 2138 |
POLB,FOXO1,EGR1,NF1,PLOD1,SLC29A1,SIRT2,HMOX2,NOL3,TGFB2,BIRC2,DDIT4,PRKCE,SHC1,SUV39H2,PMAIP1,STC2,MMP14,UTS2,LONP1,ANGPT2,BDNF,PDK1,PPARG,CDK4,KCNMA1,LDHA,RYR2,ADSL,CAV1,ANGPTL4,UBC,CAT,SMAD3,CAMK2D,ALAD,GATA6,PDLIM1,HIF1A,HIPK2,CUL2,ATG7,DPP4,ATM,RBPJ,APAF1,HMBS,TXN2 |
| 4.811e-02 | -3.03 | mitotic cell cycle process | biological process | GO:1903047 | 720 | 109 | 16441 | 2138 |
CHMP2A,CUL7,CUL4A,PCNT,BIRC6,PAFAH1B1,PPP2R2A,CSNK2A1,SMARCA4,SIRT2,NUP43,PRKCA,NUP160,PIBF1,BIRC2,LPIN1,SBDS,SMARCB1,ANAPC1,NEK6,NUP133,ANAPC11,ANAPC10,MAD1L1,PDS5B,CEP63,RAN,CEP135,CDK6,SEH1L,BRD4,TUBA1A,STAMBP,CDK4,ASUN,KIF15,ARHGEF10,MCM2,SOX4,TTC28,NUP214,TAF2,RHOU,TCF7L1,RANBP2,TRRAP,CDC16,RBBP8,MISP,E2F4,NSMCE2,RPS6KB1,NOLC1,CHMP4C,HMGA2,DCTN3,TTN,MCM6,MCM10,XPC,KHDRBS1,SIRT7,DBF4,ID2,CEP126,CSNK1A1,PSMF1,GIGYF2,POGZ,MAD2L2,POM121,SFI1,TADA3,ABL1,CEP164,CEP290,MCM5,BANF1,TRIAP1,TIMELESS,FBXO31,NUDC,DIS3L2,MYB,STAG1,ANAPC13,CRADD,PRIM2,PPAT,POLA1,FOXN3,HAUS6,TEX14,PSMA1,PLCB1,UBE2E1,UBC,RPA1,DYNC1H1,KLHL22,POLE2,GADD45A,SDCCAG8,CUL2,ORC5,ATM,PPP1R12B,BRSK2,ANAPC4 |
| 4.814e-02 | -3.03 | histone H3-K4 methylation | biological process | GO:0051568 | 32 | 8 | 16441 | 2138 |
KMT2D,ASH1L,SETD1B,WDR61,KMT2E,CTR9,KMT2C,KMT2A |
| 4.814e-02 | -3.03 | negative regulation of response to oxidative stress | biological process | GO:1902883 | 32 | 8 | 16441 | 2138 |
ATF4,TRAP1,HIF1A,PSAP,NOL3,MET,HTRA2,PYCR1 |
| 4.814e-02 | -3.03 | negative regulation of cellular response to oxidative stress | biological process | GO:1900408 | 32 | 8 | 16441 | 2138 |
ATF4,TRAP1,HIF1A,PSAP,NOL3,MET,HTRA2,PYCR1 |
| 4.815e-02 | -3.03 | CARS (cysteinyl-tRNA synthetase) | protein interactions | 833 | 40 | 10 | 16036 | 2270 |
TTC1,GARS,GART,SEC24D,PPAT,HIRIP3,JMJD6,XPO7,TROVE2,SBDS |
| 4.815e-02 | -3.03 | CCNL2 (cyclin L2) | protein interactions | 81669 | 40 | 10 | 16036 | 2270 |
SRSF2,IREB2,ABCF2,JMJD6,AP1B1,PRKCA,PTPRG,POLR2A,PRKACB,SMPDL3B |
| 4.815e-02 | -3.03 | H1FX (H1 histone family, member X) | protein interactions | 8971 | 40 | 10 | 16036 | 2270 |
CUL7,SIRT7,RSL1D1,SHMT2,RNF2,EXOSC4,BMI1,DOT1L,NOP56,TOP1 |
| 4.815e-02 | -3.03 | S100A4 (S100 calcium binding protein A4) | protein interactions | 6275 | 40 | 10 | 16036 | 2270 |
SMAD3,TOM1L2,ZZEF1,PPFIBP1,H2AFX,PSMA1,MYH9,ANXA2,IGBP1,TRIP13 |
| 4.815e-02 | -3.03 | USP34 (ubiquitin specific peptidase 34) | protein interactions | 9736 | 40 | 10 | 16036 | 2270 |
SEC24A,ELP2,SIRT7,UBXN1,LAGE3,ATM,ZRANB2,AHCYL1,CSNK1A1,STAM |
| 4.815e-02 | -3.03 | SARNP (SAP domain containing ribonucleoprotein) | protein interactions | 84324 | 40 | 10 | 16036 | 2270 |
SRPRB,SRCAP,FN1,WDR61,MRRF,FUS,SRRM2,YARS,SBDS,TIMM44 |
| 4.815e-02 | -3.03 | ENAH (enabled homolog (Drosophila)) | protein interactions | 55740 | 40 | 10 | 16036 | 2270 |
TERF2IP,ABL1,DYRK1B,EVL,DNMBP,GPHN,COPS4,FAT1,ENAH,XPO6 |
| 4.815e-02 | -3.03 | nucleoside biosynthetic process | biological process | GO:0009163 | 111 | 21 | 16441 | 2138 |
AK2,UPP1,ATP6V0A1,ADSL,APRT,CHCHD10,IMPDH2,MAT2A,ATP5D,STOML2,CAD,HPRT1,NME7,ATP5G2,SURF1,PPCDC,UMPS,CMPK1,ADK,PRPS1,NT5E |
| 4.815e-02 | -3.03 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090101 | 111 | 21 | 16441 | 2138 |
CHST11,PRDM16,HSPA5,SMAD7,CAV1,TGFBR2,ONECUT2,UBC,TCF7L2,SKI,DKK1,SKIL,SMAD3,PMEPA1,LEMD3,HIPK2,UCHL5,GLG1,PEG10,CAV2,USP15 |
| 4.817e-02 | -3.03 | RAN (RAN, member RAS oncogene family) | protein interactions | 5901 | 120 | 24 | 16036 | 2270 |
SKIV2L,RANBP6,EXOSC2,CUL7,FN1,ACTG1,XPO5,RANGAP1,CEP126,XPO7,SON,MAD2L2,ISG15,SMARCB1,ABL1,RANBP2,KPNA1,IKBKB,RNF2,FUS,RAN,AGL,XPO6,IPO11 |
| 4.820e-02 | -3.03 | GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN | MSigDB lists | GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN | 192 | 33 | 17758 | 2279 |
UNC13D,TRIM16,SEC24D,TRPM6,TRAK1,TBCCD1,RTN4,SPATS2L,SEMA6A,STC2,ZNF142,TMLHE,RPS6KB2,TLCD1,ZNF414,TSTA3,TMEM126A,WDHD1,TRAPPC6B,RBM28,SLC26A11,SLC9A5,SAP30BP,PUSL1,S100A16,YIPF2,ZNF557,TIMM17A,TBX3,WDR33,RNF214,TMEM158,TRIM36 |
| 4.820e-02 | -3.03 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | 192 | 33 | 17758 | 2279 |
WDR75,PRPF31,LPCAT3,IKBKAP,ANKRD54,ABCA7,PEX7,IDI1,LDOC1L,DCTN4,SLC39A7,PTGS1,EXOSC4,CMPK1,FDFT1,TRIM13,TUBA1A,PCCA,PPP1R21,JMJD1C,SUMO3,ATP6V0A1,TTYH2,DLST,ODC1,S100A16,MLLT10,PGD,KPNA1,ELP2,TRMT5,SQLE,HEATR1 |
| 4.820e-02 | -3.03 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | 192 | 33 | 17758 | 2279 |
KLHL24,FBXO45,ZCCHC8,SLK,HES6,RTN4,RSF1,EDC3,PAIP2,CEP290,WDR27,DCTN4,CELF1,ERRFI1,TMPO,TOP1,TTPAL,KDM3B,PCGF3,EIF4E3,RB1CC1,POLA1,PPP1R21,GDPD1,TCEB3,HIST1H2BL,CCDC28B,IFT81,EHMT2,HNRNPR,BRD9,CEP170,PTPN14 |
| 4.820e-02 | -3.03 | GSE5960_TH1_VS_ANERGIC_TH1_DN | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_DN | 192 | 33 | 17758 | 2279 |
ID1,SLC48A1,ITFG1,TMEM109,DLGAP4,SLC29A1,PRKCA,LCLAT1,REEP5,PITPNM1,SLC25A20,ECM1,NEK6,ZSWIM7,ANXA7,ANXA5,NDUFA6,AHCYL1,SRPK2,DPF3,AP4S1,APEX1,TMEM126A,RNH1,BRCA1,TPRA1,CPT1A,ECH1,ATP5D,SMARCC1,TSSC1,ACP1,PTP4A2 |
| 4.820e-02 | -3.03 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | 192 | 33 | 17758 | 2279 |
SIRT7,ID2,FOSL2,MFHAS1,PAIP2,PRKCH,CHD7,KIAA1958,ECM1,HVCN1,NEK6,DCTN4,INTS12,MGLL,PTPRK,PFKFB4,RFC3,SKAP2,LAMC1,MYO10,GLTSCR2,UPP1,MINA,ARHGEF10,RNH1,VIM,SLC39A14,SH3RF1,NSF,IRAK2,CRCP,ANXA2,DDIT3 |
| 4.820e-02 | -3.03 | GSE27786_LSK_VS_LIN_NEG_CELL_UP | MSigDB lists | GSE27786_LSK_VS_LIN_NEG_CELL_UP | 192 | 33 | 17758 | 2279 |
ZNF292,TRIP6,DPF2,MFGE8,PDK4,HES6,KCNJ14,FOXO3,SLC25A20,ANAPC10,VAPB,GLTP,TSPAN14,ZNRD1,MBTPS2,MSI2,ANTXR2,EIF4E3,FAM127A,AKAP8L,GLTSCR2,ELOVL6,MINA,TBXAS1,MEF2D,MBNL2,SEC31A,PAF1,ATXN7,LARGE,TNFRSF1A,DPP4,CTXN1 |
| 4.820e-02 | -3.03 | GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN | 192 | 33 | 17758 | 2279 |
HERC2,DCTN3,MYCBP2,DNAJA4,PRDX6,GPBP1L1,ZNF280C,NUP160,MBNL1,EEA1,FAM8A1,CDC73,SBDS,ANKRD13A,ELL,UBE3A,ENTPD5,METTL8,SSFA2,TMEM216,TCEB3,FAM126B,GPNMB,DSP,KLF6,SERP1,HERPUD1,SLC23A2,OXSR1,EPN2,USP20,TSPAN5,BAG1 |
| 4.820e-02 | -3.03 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 33 | 17758 | 2279 |
DCTN3,NCOR2,SERINC5,SPRED2,TCF3,SLC6A8,LPIN1,FARSA,NDUFV1,SHC1,DUS4L,SREBF2,ATXN2,VPS72,HRG,TOMM34,RPS6KB2,DTNB,GARS,TSTA3,CDK4,PCCA,MAK16,BSN,UBTF,KDM4B,TRAP1,E2F4,HIC2,SGSM2,TPM1,AP2S1,MEF2C |
| 4.820e-02 | -3.03 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | 192 | 33 | 17758 | 2279 |
IFT57,MIF4GD,RWDD1,ALG8,TUBE1,CHCHD10,LCLAT1,REEP5,MAN1A1,SRSF2,SHMT2,ETF1,AVEN,N4BP2,PPA1,TRIP13,HMGCR,MYB,SEC24A,DDN,AGPAT4,MTHFD1L,IMPDH2,SLC35D1,PDE2A,FOXC1,IKZF4,HIF1A,STX1A,HIPK2,FNTB,TBXA2R,CNDP2 |
| 4.820e-02 | -3.03 | GSE17721_CTRL_VS_CPG_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_0.5H_BMDM_UP | 192 | 33 | 17758 | 2279 |
CUL4A,DPF2,PPP2R2A,C11orf54,ZNF346,NLE1,FAM8A1,WNT2B,PRKCE,RTN1,IKBKB,SLC38A2,PTGS1,ZNF518B,SNAPC5,LYST,LYPLA2,MTHFD1,HMBOX1,PXN,PARP2,PPP1R21,SOX4,RAB10,ARPC3,HLCS,SERINC1,ZNF436,FNTB,TRAF3,ABCC3,GALNT10,MED20 |
| 4.823e-02 | -3.03 | REVINTRACTNG | prints domains | PR00405 | 28 | 6 | 4759 | 462 |
AGAP6,AGAP1,ASAP1,GIT2,ACAP3,ASAP3 |
| 4.828e-02 | -3.03 | NCK2 (NCK adaptor protein 2) | protein interactions | 8440 | 126 | 25 | 16036 | 2270 |
EFNB2,TNK2,TNIK,MINK1,TRIP6,KHDRBS1,ARHGAP32,PTK2,NHSL1,PEAK1,TTC28,SEMA6A,GIT2,FGFR1,UBC,EIF3H,ABL2,CHN1,IRS1,ASAP1,VPS37B,NCKIPSD,RBM26,SYNPO,SRPK2 |
| 4.831e-02 | -3.03 | chromaffin granule | cellular component | GO:0042583 | 7 | 3 | 17570 | 2233 |
CLU,ANXA7,SYT1 |
| 4.831e-02 | -3.03 | micro-ribonucleoprotein complex | cellular component | GO:0035068 | 7 | 3 | 17570 | 2233 |
AGO3,AGO2,TNRC6A |
| 4.831e-02 | -3.03 | BRCA1-A complex | cellular component | GO:0070531 | 7 | 3 | 17570 | 2233 |
BRE,BRCA1,BRCC3 |
| 4.831e-02 | -3.03 | DNA recombinase mediator complex | cellular component | GO:0033061 | 7 | 3 | 17570 | 2233 |
XRCC2,SFR1,RAD51B |
| 4.831e-02 | -3.03 | LIM_MAMMARY_LUMINAL_MATURE_UP | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_UP | 106 | 20 | 17758 | 2279 |
VOPP1,SLC40A1,ANKMY2,HES6,SCMH1,HIST1H4J,ABCA7,PHKA1,HIPK2,G6PD,TBX3,LPIN2,ACOT11,DNAJC12,MEIS3,SLC25A23,LAMA5,ZFHX2,MYB,GALE |
| 4.833e-02 | -3.03 | V$TEL2_Q6 | MSigDB lists | V$TEL2_Q6 | 226 | 38 | 17758 | 2279 |
TCF12,HM13,ITFG1,PIK3R4,ARFIP2,PPIL1,ST7L,CLINT1,TIMM10,SLC39A11,SLC30A7,SHC1,SEC24C,IKBKB,HIRIP3,CTR9,ARHGAP1,CHD2,AGL,OGG1,PNMA1,PRKACB,LYPLA2,CSGALNACT2,ZNF646,ACSL5,IL11RA,FOXN3,PTK2,DDX50,SUPT4H1,PALB2,CCDC85B,GGT7,DMTF1,ZMAT3,DDIT3,TNRC6A |
| 4.833e-02 | -3.03 | V$EVI1_04 | MSigDB lists | V$EVI1_04 | 226 | 38 | 17758 | 2279 |
SEPHS2,DNAJA4,MAP2K5,LUZP1,ADAMTS6,NECAP1,CHAC1,TGFB2,UBR5,MBNL1,SEMA6A,POGZ,NEDD4,WNT2B,MTUS1,FAM50A,ATP5G2,SAMD11,RAPGEFL1,FUT11,SOBP,SLC40A1,BDNF,NRAS,ARRDC3,PRDM1,ONECUT2,NR2F1,RERE,STOML2,KIAA0355,LUC7L3,CSMD3,RPS6KB1,NR2F2,TPM1,MID1,IPO4 |
| 4.833e-02 | -3.03 | V$AP2ALPHA_01 | MSigDB lists | V$AP2ALPHA_01 | 226 | 38 | 17758 | 2279 |
DLL4,TRERF1,CENPB,SMAD7,ZFP36L1,PTPRG,PABPC4,PHC2,ESAM,MLX,HR,KDM2A,SLC39A7,MMP14,RELB,RAPGEFL1,IGF2BP1,KIAA0922,C6orf89,PABPC1,KDM3B,DPF3,USP49,PRDM16,GNL1,ARID1A,S100A16,YTHDF2,UBTF,ZFAND3,AHNAK,SPAG9,HIF1A,CDK9,HOXA3,CSMD3,EIF2S1,SMG1 |
| 4.835e-02 | -3.03 | MCM6 (minichromosome maintenance complex component 6) | protein interactions | 4175 | 79 | 17 | 16036 | 2270 |
USP7,PMS1,MCM6,MCM10,FN1,USP49,POLK,SIRT7,DBF4,PSMA1,MCM2,RPA1,KPNA3,TP53BP1,MCM5,SRRM2,SF3A1 |
| 4.838e-02 | -3.03 | lipid catabolic process | biological process | GO:0016042 | 257 | 43 | 16441 | 2138 |
LDAH,CYP24A1,TRERF1,PRDX6,PAFAH1B1,PLA2G12A,SIRT2,ABHD6,LPIN1,ETFB,DECR1,PEX7,LPIN2,PNPLA4,PNPLA3,MGLL,PRKACB,HSD17B14,MCEE,ACADS,DDHD1,SESN2,RAB7A,PCCA,GPCPD1,CPT1A,PLCB1,ACOXL,NAPEPLD,MMAA,NEU1,PLCXD2,ECH1,SMPDL3B,IRS1,DAGLA,ETFDH,DAGLB,ACOX1,SRD5A3,BDH2,PEX13,CPT1C |
| 4.839e-02 | -3.03 | cytoplasmic transport | biological process | GO:0016482 | 756 | 114 | 16441 | 2138 |
IMMP2L,THOC5,DDX19A,RPS29,VTI1A,DENND3,NUP160,SEC16A,EEA1,RPAIN,GBF1,VPS18,SRPRB,EXOC1,RPS16,SRSF2,NSRP1,NUP133,CNIH3,NCKIPSD,AP1M1,BCAP29,CORO1A,RAN,AHCYL1,CPSF3,ZC3H3,IPO11,AUP1,LYST,TIMM50,SEC24A,GDAP1,RAB7A,NOL6,ATXN1,AKAP13,NUP214,LSG1,RAB10,KIF16B,PEX1,TIMM44,RANBP2,RBSN,KPNA3,TIMM17A,CTAGE5,VPS13D,SGSM2,FIS1,NMD3,SMG1,HM13,STX8,SEC24D,STXBP6,CAMK1,TRAK1,PIK3R4,SMG7,MON2,TGFB2,NOL3,SSR4,XPO7,TIMM10,RSRC1,RHBDD1,TMCO6,ANKRD54,NEDD4,PRKCE,PEX7,MLX,SEC24C,PMPCA,TNPO3,VAPB,UPF2,TOMM34,USE1,TIMM8B,FGF9,RANBP6,TRAPPC9,FGF2,XPO5,RYR2,PACS1,TRAPPC6B,PDE2A,NOP58,HERPUD1,TCF7L2,RERE,MFN2,SEC31A,VPS13C,KPNA1,MYBBP1A,KIDINS220,RPL28,NSF,SRP68,SET,NCBP2,PEX13,NAPA,XPO6,SRP14,DDIT3,IPO4,SGSM3 |
| 4.842e-02 | -3.03 | rhythmic process | biological process | GO:0048511 | 298 | 49 | 16441 | 2138 |
IMMP2L,ID1,EGR1,NPAS2,CSNK2A1,ID2,BTBD9,BHLHE40,TGFB2,ENOX1,FOXO3,NAMPT,MMP7,UBE3A,SUV39H2,ZFHX3,VGF,MMP14,RELB,TIMELESS,KDM5C,MSH4,PRMT5,NRIP1,KMT2A,PRF1,TOP1,ARNTL2,ATF4,KDM5B,PPARG,PSPC1,KDM5A,CDK4,KCNMA1,CPT1A,FOXC1,UBC,ANXA1,HTR7,MYBBP1A,SRRD,ADNP,PER1,TAF4,ARNTL,NCOR1,BMP4,NOCT |
| 4.848e-02 | -3.03 | V$CDPCR1_01 | MSigDB lists | V$CDPCR1_01 | 119 | 22 | 17758 | 2279 |
RTN4RL2,PIGN,PHF3,EGR1,GINS3,DPH1,WDPCP,RLF,SON,MBNL1,TCF7L2,ATXN7L1,ZNF827,GRIK4,GART,TMEM237,CUL2,TBX3,CSMD3,ETV1,C15orf41,ATXN7L2 |
| 4.850e-02 | -3.03 | CHANDRAN_METASTASIS_DN | MSigDB lists | CHANDRAN_METASTASIS_DN | 288 | 47 | 17758 | 2279 |
FAM208B,PDE4B,DDR2,RNF43,TUBB6,IQGAP2,PCDH7,TMEM150C,CNST,TSPAN2,PRICKLE2,GSTA4,PCOLCE2,CAV2,CPSF3L,HSD17B14,ANTXR2,THSD4,EIF3J,FOXN3,PSPC1,NFIA,C11orf80,ASAP3,ARHGEF10,KLF6,SMPDL3B,MLLT10,SMAD3,FAM135A,GSTO2,ALKBH3,PMEPA1,KLF4,HSPB8,AHNAK2,PPP1R12B,DPP4,SEMA3C,RWDD2B,BMP4,ZAK,ECHDC1,SPOCK3,ZNF532,ARHGAP27,NR2C2AP |
| 4.852e-02 | -3.03 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 500 | 77 | 17775 | 2278 |
PDK4,DDR2,TRPM6,MKS1,CSNK2A1,RIPK1,STK33,PRKCA,UBR5,MAP2K3,RIOK2,ABL2,PRKD3,NEK6,RPS6KL1,IKBKB,ADCK4,MET,CDK6,CDK12,PRKACB,SRPK2,TNK2,NRAS,BRD4,PDK1,CDK4,ALDH1L2,NOL8,TFPI,KSR2,SGK2,STK10,FGFR1,DYRK1B,CAMK2D,TRRAP,HIPK2,RPS6KB1,RIOK1,MDN1,PDCD11,SMG1,BCKDK,TNIK,BRAF,SEC24D,MAP3K13,SUPT6H,CLK1,TAF1,CAMK1,TRIO,PIK3R4,TGFBR2,CSNK1A1,PRKCE,PRKCH,ABL1,MAP3K12,RPS6KB2,CLK2,SIK3,CAMKK2,TEX14,OBSCN,OXSR1,TRIB3,KIDINS220,TMEM237,RIOK3,ATM,TBCK,RPS6KC1,MAP2K4,ZAK,STK4 |
| 4.853e-02 | -3.03 | microtubule organizing center part | cellular component | GO:0044450 | 140 | 25 | 17570 | 2233 |
HERC2,CEP83,PCNT,CEP295,PAX2,PDE4B,MKS1,TUBE1,CCDC113,BRCA1,SIRT2,PIBF1,HSPA1A,SFI1,HSPA1B,BLOC1S2,CEP164,CEP290,SDCCAG8,CCDC146,CEP63,RAN,CEP135,CEP170,CEP128 |
| 4.860e-02 | -3.02 | QKI (QKI, KH domain containing, RNA binding) | protein interactions | 9444 | 62 | 14 | 16036 | 2270 |
PTBP2,SERF2,FN1,RBFOX2,MED27,MED15,RNF138,MED24,ATXN1,MED16,HNRNPLL,PSMF1,CARM1,POLR2A |
| 4.860e-02 | -3.02 | TNNT1 (troponin T type 1 (skeletal, slow)) | protein interactions | 7138 | 62 | 14 | 16036 | 2270 |
SEC31A,TNNC1,SNW1,OSBP2,CHD3,TFIP11,TRA2A,CCDC85B,TBPL1,VIM,MARS,TPM1,PNMA1,BLOC1S2 |
| 4.860e-02 | -3.02 | RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) | protein interactions | 58490 | 62 | 14 | 16036 | 2270 |
SRM,SURF2,DUS3L,ALAD,SUPT6H,ACTR3,RANGAP1,BRCA1,BAG1,POLR2A,TERF2,RPA1,TOM1L1,LPP |
| 4.860e-02 | -3.02 | SREBF2 (sterol regulatory element binding transcription factor 2) | protein interactions | 6721 | 62 | 14 | 16036 | 2270 |
SMAD3,TTC1,INSIG2,TRRAP,EGR1,SREBF2,INSIG1,COPS5,HSPA5,ATXN1,ATF7IP,ITGB4,ZMYM2,CASP8AP2 |
| 4.868e-02 | -3.02 | glucosyltransferase activity | molecular function | GO:0046527 | 16 | 5 | 16491 | 2164 |
GYG1,ALG5,ALG6,ALG8,KDELC1 |
| 4.869e-02 | -3.02 | Cyanoamino acid metabolism | KEGG pathways | ko00460 | 7 | 3 | 6908 | 881 |
GGT1,SHMT2,GGT7 |
| 4.869e-02 | -3.02 | Cyanoamino acid metabolism | KEGG pathways | hsa00460 | 7 | 3 | 6908 | 881 |
GGT1,SHMT2,GGT7 |
| 4.870e-02 | -3.02 | GENTILE_RESPONSE_CLUSTER_D3 | MSigDB lists | GENTILE_RESPONSE_CLUSTER_D3 | 62 | 13 | 17758 | 2279 |
RFC4,TRIM13,POLE2,ADNP,LSM14A,MBD2,RIPK1,MCL1,SLC25A44,BMI1,HERPUD1,POM121,DKK1 |
| 4.870e-02 | -3.02 | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP | MSigDB lists | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP | 62 | 13 | 17758 | 2279 |
KLHL24,USE1,KDM6B,SERF2,C12orf76,H2AFJ,TMEM219,SLC9B2,TIGD1,TBCK,C15orf57,MAML3,NT5E |
| 4.870e-02 | -3.02 | INTERPHASE_OF_MITOTIC_CELL_CYCLE | MSigDB lists | INTERPHASE_OF_MITOTIC_CELL_CYCLE | 62 | 13 | 17758 | 2279 |
ABL1,CUL4A,TAF1,POLA1,KHDRBS1,FOXN3,CDK4,CUL2,DBF4,ANAPC10,TBRG4,CDK6,ANAPC4 |
| 4.873e-02 | -3.02 | SAGIV_CD24_TARGETS_DN | MSigDB lists | SAGIV_CD24_TARGETS_DN | 44 | 10 | 17758 | 2279 |
KLHL22,ECM1,MCAM,UROD,HSPB8,RELB,CAV1,CHAC1,OASL,OGG1 |
| 4.873e-02 | -3.02 | ABRAMSON_INTERACT_WITH_AIRE | MSigDB lists | ABRAMSON_INTERACT_WITH_AIRE | 44 | 10 | 17758 | 2279 |
GEMIN5,RANBP2,MYBBP1A,MCM6,SRSF2,MCM5,MCM2,PABPC1,POLR2A,NOP56 |
| 4.873e-02 | -3.02 | NAKAMURA_METASTASIS | MSigDB lists | NAKAMURA_METASTASIS | 44 | 10 | 17758 | 2279 |
DDX24,ACD,PDE10A,SDCCAG8,AKAP13,TUBB6,ETV1,SMYD3,PLEKHG4,CMTM3 |
| 4.873e-02 | -3.02 | salivary_gland-maxilla-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-maxilla-carcinoma-adenoid_cystic_carcinoma | 56 | 12 | 17775 | 2278 |
RBM20,BRAF,NRAS,SUFU,SPEN,TBXAS1,SLC26A11,SYNPO,SOX6,MGA,FAM184A,MTHFD1 |
| 4.877e-02 | -3.02 | V$MIF1_01 | MSigDB lists | V$MIF1_01 | 172 | 30 | 17758 | 2279 |
CARS,BDNF,HM13,WARS2,PRKCSH,MRPL10,TMEM109,RFX2,PLA2G12A,ARID1A,TBC1D16,BMP6,NCDN,IFT81,SOCS1,DNAJC1,TP53BP1,KIAA0355,ARL4A,ARL13B,TBPL1,AP1M1,SDCBP2,CSMD3,DDX31,ADCK4,CD44,ERRFI1,ADK,SPTAN1 |
| 4.877e-02 | -3.02 | GSE10325_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_DN | 172 | 30 | 17758 | 2279 |
ARHGAP17,ADAM19,DNMBP,LAMC1,SKAP2,IFNGR2,TCF3,GNG7,TRAK1,TUBB6,TCTN1,DENND3,HLA-DMA,RNF141,DDAH2,PDLIM1,SYNGR2,CLCN6,LARGE,TIMELESS,SHMT2,NT5C,SCARB1,MAP3K14,ADK,SYNPO,RAB30,MICAL3,PTPRK,MEF2C |
| 4.889e-02 | -3.02 | Transl_B-barrel | interpro domains | IPR009000 | 27 | 7 | 18293 | 2341 |
EIF5B,GUF1,GFM2,MTIF2,AARS,EEFSEC,AARS2 |
| 4.889e-02 | -3.02 | RNA-helicase_DEAD-box_CS | interpro domains | IPR000629 | 27 | 7 | 18293 | 2341 |
DDX3X,DDX31,DDX24,DDX10,DDX18,DDX49,EIF4A2 |
| 4.894e-02 | -3.02 | protein homodimerization activity | molecular function | GO:0042803 | 707 | 108 | 16491 | 2164 |
SRM,TCF12,MYCBP2,ID1,RAB11FIP4,PAFAH1B1,NTSR1,MYO7A,RCHY1,MYH9,PLOD1,SBF2,EEA1,GABPB2,DST,NRF1,ASNS,S100A10,TBC1D22A,IKBKB,GSTA4,CORO1A,KMT2A,MGLL,CARM1,NR6A1,CPOX,LGALS1,MCL1,MTHFD1L,KCNH2,ODC1,STK10,FGFR1,S100A16,MGST1,SMAD3,DNTTIP1,CAMK2D,HPRT1,IKZF4,HLCS,G6PD,ATG7,XPNPEP1,DPP4,RUNX1,MID1,EMSY,CHMP4C,CADM4,TNNC1,CARS,AOC3,HM13,DROSHA,JUP,ZHX3,MAP3K13,SLK,TCF3,TGFB2,BHLHE40,TIMM10,CD226,YARS2,NAMPT,ADH5,RNF40,PEX7,MLX,PVRL3,ATIC,STC2,SDCBP2,VAPB,TIMELESS,TENM3,HARS2,RDX,MAP3K12,PRPS1,CAV2,DMRT1,TERF2,HMGCR,HOMER2,IL6R,PDE2A,PLCB1,TRIM37,TARS,ANXA1,CAT,TPD52L2,COQ9,IRAK2,RRAGA,MSH3,SLC16A1,BMP4,NR2F2,RABEP1,TESC,DDIT3,STK4,LRRC41,GALE |
| 4.898e-02 | -3.02 | ISG15 (ISG15 ubiquitin-like modifier) | protein interactions | 9636 | 187 | 35 | 16036 | 2270 |
PRDX6,CLK1,PAFAH1B1,MYH9,FARS2,PLOD1,CSNK2A1,NUP43,PHGDH,AARS,HSPA1A,FLNB,NEDD4,ATXN2,IFIT5,ATIC,UBAP2L,ANXA5,RAN,UTP4,SERBP1,ARID5B,ABCF2,LDHA,VIM,PALLD,TARS,RDH11,PGD,WARS,TAF2,EPRS,AHNAK,ANXA2,WDR33 |
| 4.903e-02 | -3.02 | regulation of cellular protein catabolic process | biological process | GO:1903362 | 312 | 51 | 16441 | 2138 |
USP7,TAF1,UBXN1,NKD2,OPHN1,SMAD7,RCHY1,CSNK2A1,SIRT2,PSMF1,MAD2L2,RNF40,ANAPC1,UBE3A,NEK6,UCHL5,WAC,ANAPC11,ANAPC10,MAD1L1,RDX,FHIT,USP49,USP42,TEX14,SUMO3,PSMA1,USP10,CAV1,PTK2,UBE2K,HERPUD1,ARIH2,USP36,UBE2E1,UBC,FBXL5,TRIB3,KLHL22,CDC16,SMARCC1,NSMCE2,SOCS4,ATM,USP20,ANXA2,CLU,USP11,UQCC2,ANAPC4,USP15 |
| 4.907e-02 | -3.01 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN | 87 | 17 | 17758 | 2279 |
EIF3C,DDX24,NOL6,LDHA,IMPDH2,SPATS2,CA5B,PHLDA2,HPRT1,SRSF2,SMARCC1,SYNCRIP,MBD2,MYC,TRIAP1,BUD31,NOLC1 |
| 4.907e-02 | -3.01 | BRUINS_UVC_RESPONSE_MIDDLE | MSigDB lists | BRUINS_UVC_RESPONSE_MIDDLE | 87 | 17 | 17758 | 2279 |
FBXO17,CHST11,TRIM13,DDX41,SEC24D,IFT43,SLC25A12,PTK2,SAP30BP,LPIN1,ZNF622,CCNT1,NSMCE2,WDR73,POLR1E,DDIT3,SAP30 |
| 4.917e-02 | -3.01 | BIOCARTA_PPARA_PATHWAY | MSigDB lists | BIOCARTA_PPARA_PATHWAY | 56 | 12 | 17758 | 2279 |
NCOR2,FAT1,MYC,ACOX1,ME1,NCOR1,PRKCA,NRIP1,SRA1,PRKAR2A,PRKACB,NR2F1 |
| 4.917e-02 | -3.01 | LUCAS_HNF4A_TARGETS_UP | MSigDB lists | LUCAS_HNF4A_TARGETS_UP | 56 | 12 | 17758 | 2279 |
ATXN7L1,ETFDH,DDAH2,CAMKK2,DSC2,PRKCSH,ACOX1,SLC35D1,DNAJC22,BIRC2,MAN1A1,SLC25A20 |
| 4.918e-02 | -3.01 | positive regulation of transcription from RNA polymerase II promoter | biological process | GO:0045944 | 1009 | 149 | 16441 | 2138 |
ZNF292,AAMDC,ATRX,PPARGC1B,HLTF,CCNL2,SIRT2,GABPB2,LPIN1,SKI,SMARCB1,SREBF2,RELB,ZEB1,RNF111,ZNF148,MEIS3,ETV1,DDN,ATF4,PPARG,NR6A1,GNL3,HSPA5,NFIA,CUX1,SUPT20H,BRCA1,SOX4,MLLT10,DDX3X,PAF1,TCF7L1,SUPT4H1,INSIG1,GATA6,TP53BP1,CCNT1,PER1,E2F4,MKL2,TNFRSF1A,RUNX1,DLX2,MEF2C,FOXO1,EGR1,JUP,TAF1,PAX2,SMAD7,PID1,BARX2,RLF,CDC73,NAMPT,ELL,SUB1,MYC,BUD31,GTF2H1,CTR9,NRIP1,MYB,WDR61,PAXBP1,STAG1,EIF2A,SUPT5H,ONECUT2,TCF7L2,ATXN7,HIF1A,CDK9,TBL1X,SMYD3,TCF12,ASH1L,MAP2K5,NPAS2,RIPK1,PBX1,SMARCA4,FOSL2,PELP1,KDM1A,BLOC1S2,NRF1,JAG1,CAMTA2,LPIN2,IKBKB,MET,KMT2A,MAML3,MOSPD1,KMT2D,BRD4,DDX41,GRHL3,ATXN1,SATB2,MEF2D,VDR,SMAD3,TAF2,SMARCC1,IKZF4,SIX5,COPS5,HIPK2,KLF4,CEBPZ,ARNTL,PUS1,HMGA2,INSIG2,SUPT6H,CAMK1,TCF3,AGO2,ID2,RPS6KA5,FOXO3,BMP6,SNW1,TRIAP1,DMRT1,SOX6,PKNOX1,MBTPS2,ARNTL2,KDM6B,SLC40A1,MSX1,FGF2,ZNF821,MEN1,KLF6,FOXC1,UBC,RERE,ARID3B,CSRNP1,BCAS3,RBPJ,BMP4,IGBP1,DDIT3 |
| 4.918e-02 | -3.01 | Desmosomal_cadherin | interpro domains | IPR009122 | 7 | 3 | 18293 | 2341 |
DSC3,DSC2,DSG2 |
| 4.918e-02 | -3.01 | Pre-SET_dom | interpro domains | IPR007728 | 7 | 3 | 18293 | 2341 |
SUV39H2,EHMT2,EHMT1 |
| 4.918e-02 | -3.01 | Nuc_translocat | interpro domains | IPR001067 | 7 | 3 | 18293 | 2341 |
ARNTL2,NPAS2,ARNTL |
| 4.918e-02 | -3.01 | GP_PDE_dom | interpro domains | IPR030395 | 7 | 3 | 18293 | 2341 |
GDPD5,GPCPD1,GDPD1 |
| 4.918e-02 | -3.01 | Znf_UBR | interpro domains | IPR003126 | 7 | 3 | 18293 | 2341 |
UBR1,UBR4,UBR5 |
| 4.918e-02 | -3.01 | Sirtuin | interpro domains | IPR003000 | 7 | 3 | 18293 | 2341 |
SIRT2,SIRT6,SIRT7 |
| 4.918e-02 | -3.01 | Ssirtuin_cat_dom | interpro domains | IPR026590 | 7 | 3 | 18293 | 2341 |
SIRT2,SIRT6,SIRT7 |
| 4.918e-02 | -3.01 | Di19_Zn_binding_dom | interpro domains | IPR008598 | 7 | 3 | 18293 | 2341 |
ZEB1,RNF138,RNF114 |
| 4.918e-02 | -3.01 | Thr/Ala-tRNA-synth_IIc_edit | interpro domains | IPR018163 | 7 | 3 | 18293 | 2341 |
AARS,TARS,AARS2 |
| 4.918e-02 | -3.01 | CUT_dom | interpro domains | IPR003350 | 7 | 3 | 18293 | 2341 |
SATB2,ONECUT2,CUX1 |
| 4.918e-02 | -3.01 | G_CP_dom | interpro domains | IPR030378 | 7 | 3 | 18293 | 2341 |
GNL1,LSG1,GNL3 |
| 4.918e-02 | -3.01 | Elp3/MiaB/NifB | interpro domains | IPR006638 | 7 | 3 | 18293 | 2341 |
CDKAL1,LIAS,ELP3 |
| 4.918e-02 | -3.01 | Pept_C19_DUSP | interpro domains | IPR006615 | 7 | 3 | 18293 | 2341 |
USP20,USP11,USP15 |
| 4.918e-02 | -3.01 | Plectin_repeat | interpro domains | IPR001101 | 7 | 3 | 18293 | 2341 |
DST,EVPL,DSP |
| 4.918e-02 | -3.01 | MODULE_123 | MSigDB lists | MODULE_123 | 240 | 40 | 17758 | 2279 |
ZNF254,HMGA2,ZNF516,CUL4A,EGR1,PAX2,RCAN1,HLTF,FOSL2,RLF,TOX4,ELL,NRF1,ZFHX3,MYC,GTF2H1,CHD2,KDM5C,ETV1,ZNF646,MSX1,ZNF124,ZNF195,PPARG,TLE3,FOXN3,KDM5A,TCEB3,RFX2,TBRG4,C5AR1,POU2F1,MEF2D,BRCA1,SOX4,MEN1,KLF6,PER1,TAF4,ZBTB24 |
| 4.918e-02 | -3.01 | V$IRF7_01 | MSigDB lists | V$IRF7_01 | 240 | 40 | 17758 | 2279 |
SLC12A7,TCF12,COMMD10,DLL4,MAP2K5,C16orf52,PPP2R2A,ZFP36L1,PLEK2,PABPC4,FAM50A,SOCS1,NOVA2,ATP5G2,UPF2,SOBP,HMBOX1,MSX1,EVL,RBCK1,PRDM16,AGPAT4,RDH10,ARRDC3,OASL,ZDHHC14,SOX4,CPT1A,DDX60,ANGPTL4,UBR4,ISG15,YTHDF2,EXOC6,KPNA3,GATA6,CUL2,INTS9,RPS6KB1,NRP1 |
| 4.923e-02 | -3.01 | MENSSEN_MYC_TARGETS | MSigDB lists | MENSSEN_MYC_TARGETS | 50 | 11 | 17758 | 2279 |
SRM,EPRS,APEX1,NSF,TRAP1,CDK4,LDHA,BRCA1,SCARB1,MGST1,NOP56 |
| 4.923e-02 | -3.01 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | 50 | 11 | 17758 | 2279 |
FLNC,SH2B3,BDNF,ARHGAP17,TRIO,ZEB1,TRAF3,MB21D2,TTC28,MMP16,CMTM3 |
| 4.929e-02 | -3.01 | MOB1A (MOB kinase activator 1A) | protein interactions | 55233 | 51 | 12 | 16036 | 2270 |
DST,TRIP6,CCDC85B,TSSC1,FAM118A,AMOT,DOCK6,CMTM3,PTPN14,IPO11,STK4,LRCH1 |
| 4.929e-02 | -3.01 | MED6 (mediator complex subunit 6) | protein interactions | 10001 | 51 | 12 | 16036 | 2270 |
SMAD3,VDR,EHMT2,MED27,MED15,MED13L,MED24,SMARCA4,MED18,MED16,MED20,ZC3H13 |
| 4.929e-02 | -3.01 | TBL1XR1 (transducin (beta)-like 1 X-linked receptor 1) | protein interactions | 79718 | 51 | 12 | 16036 | 2270 |
SNU13,SMARCC1,SIRT6,SMARCD3,RNF2,TBL1X,NCOR1,EIF2A,ABCF1,KDM1A,SKI,SMARCB1 |
| 4.937e-02 | -3.01 | peritoneum-carcinoma-peritoneal_serous_surface_carcinoma | COSMIC cancer mutations | peritoneum-carcinoma-peritoneal_serous_surface_carcinoma | 7 | 3 | 17775 | 2278 |
BRCA2,BRAF,BRCA1 |
| 4.937e-02 | -3.01 | adenoma-hyperplasia_NS | COSMIC cancer mutations | adenoma-hyperplasia_NS | 7 | 3 | 17775 | 2278 |
BRAF,MEN1,CDC73 |
| 4.937e-02 | -3.01 | peritoneal_serous_surface_carcinoma | COSMIC cancer mutations | peritoneal_serous_surface_carcinoma | 7 | 3 | 17775 | 2278 |
BRCA2,BRAF,BRCA1 |
| 4.937e-02 | -3.01 | skin-lower_extremity-malignant_melanoma | COSMIC cancer mutations | skin-lower_extremity-malignant_melanoma | 7 | 3 | 17775 | 2278 |
BRAF,NRAS,MET |
| 4.937e-02 | -3.01 | parathyroid-adenoma-hyperplasia_NS | COSMIC cancer mutations | parathyroid-adenoma-hyperplasia_NS | 7 | 3 | 17775 | 2278 |
BRAF,MEN1,CDC73 |
| 4.937e-02 | -3.01 | nasal_cavity | COSMIC cancer mutations | nasal_cavity | 7 | 3 | 17775 | 2278 |
BRAF,NRAS,SPEN |
| 4.937e-02 | -3.01 | salivary_gland-nasal_cavity-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-nasal_cavity-carcinoma-adenoid_cystic_carcinoma | 7 | 3 | 17775 | 2278 |
BRAF,NRAS,SPEN |
| 4.937e-02 | -3.01 | ovary-adenoma | COSMIC cancer mutations | ovary-adenoma | 7 | 3 | 17775 | 2278 |
BRCA2,BRAF,BRCA1 |
| 4.937e-02 | -3.01 | skin-upper_extremity-malignant_melanoma | COSMIC cancer mutations | skin-upper_extremity-malignant_melanoma | 7 | 3 | 17775 | 2278 |
BRAF,NRAS,MET |
| 4.942e-02 | -3.01 | MEVGALKINASE | prints domains | PR00959 | 4 | 2 | 4759 | 462 |
MVK,GALK2 |
| 4.942e-02 | -3.01 | LCACHANNELB | prints domains | PR01626 | 4 | 2 | 4759 | 462 |
CACNB1,CACNB2 |
| 4.942e-02 | -3.01 | TROPOMYOSIN | prints domains | PR00194 | 4 | 2 | 4759 | 462 |
TPM1,TPM4 |
| 4.942e-02 | -3.01 | TRNASYNTHASP | prints domains | PR01042 | 4 | 2 | 4759 | 462 |
NARS2,NARS |
| 4.944e-02 | -3.01 | G Protein Signaling Pathways | WikiPathways | WP35 | 95 | 18 | 4455 | 564 |
GNB3,NRAS,PDE4A,GNG7,PDE4B,AKAP12,AKAP13,PRKCA,PDE8B,GNAI1,PRKCH,PRKCE,PRKD3,PPP3CC,AKAP11,PRKAR2A,GNG5,PRKACB |
| 4.950e-02 | -3.01 | NUMA1 (nuclear mitotic apparatus protein 1) | protein interactions | 4926 | 85 | 18 | 16036 | 2270 |
CCDC57,CUL7,BRD4,SMARCAD1,SIRT7,ZC3H18,BRCA1,CDC73,EIF3H,RPA1,GNAI1,TERF2IP,TP53BP1,BANF1,RNF2,BMI1,CDK6,TERF2 |
| 4.950e-02 | -3.01 | MATR3 (matrin 3) | protein interactions | 9782 | 85 | 18 | 16036 | 2270 |
CUL7,PTBP2,FN1,UTP14A,SIRT6,TNFRSF21,SMARCAD1,NFX1,SF3A3,UBC,RPA1,STOML2,SUB1,RANBP2,SNAP23,COPS5,CDK9,H2AFX |
| 4.953e-02 | -3.01 | telomere organization | biological process | GO:0032200 | 86 | 17 | 16441 | 2138 |
RFC4,RFC3,PRIM2,APEX1,POLA1,HIST1H4J,DKC1,TNKS1BP1,RPA1,TERF2IP,SLX4,ACD,POLE2,NSMCE2,ATM,CTC1,TERF2 |
| 4.953e-02 | -3.01 | HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_UP | MSigDB lists | HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_UP | 27 | 7 | 17758 | 2279 |
FKBP1A,DSC3,ARHGAP32,KDM4B,ABHD3,TCEB3,ZNF512B |
| 4.953e-02 | -3.01 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | MSigDB lists | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | 27 | 7 | 17758 | 2279 |
RANBP2,RAN,NUP43,NUP214,NUP133,SEH1L,POM121 |
| 4.953e-02 | -3.01 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | MSigDB lists | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | 27 | 7 | 17758 | 2279 |
RANBP2,NUP43,KPNA1,NUP214,NUP133,POM121,SEH1L |
| 4.953e-02 | -3.01 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | MSigDB lists | REACTOME_ELONGATION_ARREST_AND_RECOVERY | 27 | 7 | 17758 | 2279 |
ELL,SUPT4H1,SUPT5H,CCNT1,CDK9,POLR2A,TCEB3 |
| 4.953e-02 | -3.01 | REACTOME_EXTENSION_OF_TELOMERES | MSigDB lists | REACTOME_EXTENSION_OF_TELOMERES | 27 | 7 | 17758 | 2279 |
RFC4,RFC3,POLE2,DKC1,PRIM2,POLA1,RPA1 |
| 4.955e-02 | -3.00 | PETRETTO_LEFT_VENTRICLE_MASS_QTL_CIS_DN | MSigDB lists | PETRETTO_LEFT_VENTRICLE_MASS_QTL_CIS_DN | 7 | 3 | 17758 | 2279 |
NSD1,ZNF346,AGTPBP1 |
| 4.955e-02 | -3.00 | chr1p | MSigDB lists | chr1p | 7 | 3 | 17758 | 2279 |
SF3A3,ZBTB17,AP4B1 |
| 4.955e-02 | -3.00 | TERAMOTO_OPN_TARGETS_CLUSTER_5 | MSigDB lists | TERAMOTO_OPN_TARGETS_CLUSTER_5 | 7 | 3 | 17758 | 2279 |
GON4L,CCDC53,GIGYF2 |
| 4.978e-02 | -3.00 | STK40 (serine/threonine kinase 40) | protein interactions | 83931 | 15 | 5 | 16036 | 2270 |
TRIB3,COPS6,ZNF397,FOSL2,ETV1 |
| 4.978e-02 | -3.00 | SFR1 (SWI5-dependent homologous recombination repair protein 1) | protein interactions | 119392 | 15 | 5 | 16036 | 2270 |
RNF40,EXOC1,HMBOX1,TFIP11,DTNBP1 |
| 4.978e-02 | -3.00 | NLE1 (notchless homolog 1 (Drosophila)) | protein interactions | 54475 | 15 | 5 | 16036 | 2270 |
NIFK,SKIV2L2,HNRNPH3,SIRT7,MTHFD1 |
| 4.978e-02 | -3.00 | OAS3 (2'-5'-oligoadenylate synthetase 3) | protein interactions | 4940 | 15 | 5 | 16036 | 2270 |
ZNF622,GNL3,FTSJ3,PABPC4,TOP1 |
| 4.978e-02 | -3.00 | FLG (filaggrin) | protein interactions | 2312 | 15 | 5 | 16036 | 2270 |
CSNK2A1,MCL1,UCHL5,CUL2,PCSK6 |
| 4.978e-02 | -3.00 | Mad2l2 (MAD2 mitotic arrest deficient-like 2) | protein interactions | 71890 | 15 | 5 | 16036 | 2270 |
C20orf196,EHMT2,POGZ,MAD2L2,EHMT1 |
| 4.978e-02 | -3.00 | HIST1H2BJ (histone cluster 1, H2bj) | protein interactions | 8970 | 15 | 5 | 16036 | 2270 |
JMJD6,FN1,APLF,E2F4,SIRT7 |
| 4.978e-02 | -3.00 | FAM114A1 (family with sequence similarity 114, member A1) | protein interactions | 92689 | 15 | 5 | 16036 | 2270 |
AKT1S1,SPG21,SEC24D,PPAT,TARS |
| 4.978e-02 | -3.00 | ZCCHC3 (zinc finger, CCHC domain containing 3) | protein interactions | 85364 | 15 | 5 | 16036 | 2270 |
NIFK,LIN28B,BMI1,TRA2A,SIRT7 |
| 4.978e-02 | -3.00 | DDX10 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 10) | protein interactions | 1662 | 15 | 5 | 16036 | 2270 |
PWP1,SRFBP1,DDX56,SIRT7,PUM3 |
| 4.978e-02 | -3.00 | CCDC130 (coiled-coil domain containing 130) | protein interactions | 81576 | 15 | 5 | 16036 | 2270 |
JUP,UBR1,ZZEF1,HECTD3,MINA |
| 4.978e-02 | -3.00 | FAM50B (family with sequence similarity 50, member B) | protein interactions | 26240 | 15 | 5 | 16036 | 2270 |
CCDC57,KPNA3,TRIM37,TFIP11,CCDC85B |
| 4.978e-02 | -3.00 | KDM4B (lysine (K)-specific demethylase 4B) | protein interactions | 23030 | 15 | 5 | 16036 | 2270 |
DDX3X,SNU13,KMT2D,KMT2C,ZNF414 |
| 4.978e-02 | -3.00 | TRUB2 (TruB pseudouridine (psi) synthase family member 2) | protein interactions | 26995 | 15 | 5 | 16036 | 2270 |
LIN28B,TRA2A,ZC3H3,YARS2,MRPS30 |
| 4.978e-02 | -3.00 | HIST1H4C (histone cluster 1, H4c) | protein interactions | 8364 | 15 | 5 | 16036 | 2270 |
CUL7,FN1,UCHL5,COPS5,CUL2 |
| 4.978e-02 | -3.00 | SLAMF7 (SLAM family member 7) | protein interactions | 57823 | 15 | 5 | 16036 | 2270 |
YIF1A,PTCD2,DAGLB,LEMD3,LGALS1 |
| 4.978e-02 | -3.00 | HIST1H4K (histone cluster 1, H4k) | protein interactions | 8362 | 15 | 5 | 16036 | 2270 |
CUL7,FN1,UCHL5,COPS5,CUL2 |
| 4.978e-02 | -3.00 | SFI1 (SFI1 centrin binding protein) | protein interactions | 9814 | 15 | 5 | 16036 | 2270 |
CCDC57,RADIL,MAD2L2,GCSH,SFI1 |
| 4.978e-02 | -3.00 | QPCTL (glutaminyl-peptide cyclotransferase-like) | protein interactions | 54814 | 15 | 5 | 16036 | 2270 |
RNF2,E2F4,POLR1E,MYC,AGO3 |
| 4.978e-02 | -3.00 | CCNT2 (cyclin T2) | protein interactions | 905 | 15 | 5 | 16036 | 2270 |
BRD4,SUPT5H,CDK9,CDK6,TERF2 |
| 4.978e-02 | -3.00 | MKRN2 (makorin ring finger protein 2) | protein interactions | 23609 | 15 | 5 | 16036 | 2270 |
HIBCH,NIFK,RBCK1,UBE2K,TRA2A |
| 4.987e-02 | -3.00 | V$HNF4ALPHA_Q6 | MSigDB lists | V$HNF4ALPHA_Q6 | 254 | 42 | 17758 | 2279 |
SSH2,RHOBTB1,PID1,RTN4,DNAJC22,SEMA6A,GBF1,MAP2K3,PCDH7,ZNF804A,ESAM,GART,NEK6,VGF,TIMELESS,SHF,S100A14,KDM5C,VCL,RREB1,ZFYVE1,RAPGEF4,SETD2,PRDM1,UBE2K,SON,NR2F1,NCDN,S100A16,STOML2,PMEPA1,TP53BP1,HNRNPR,ZBTB12,CSRNP1,FKBP5,TPM1,NR2F2,NRP1,BRWD3,ZAK,ATXN7L2 |